diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..478fe0bec4075ef6f93fceb585d005522cabe3cd --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tyrosine-protein kinase, active site [IPR008266]"} \ No newline at end of file diff --git a/interpro_active_site/advanced/plot_0.png b/interpro_active_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1636fb62d77064f8788e2197baed4c8580a2e31c --- /dev/null +++ b/interpro_active_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:40c073babeada976c8c2e013bbbf6b10f2ca69bee811034f3abc53ccfa52615e +size 181981 diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..478fe0bec4075ef6f93fceb585d005522cabe3cd --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tyrosine-protein kinase, active site [IPR008266]"} \ No newline at end of file diff --git a/interpro_active_site/basic/plot_0.png b/interpro_active_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..8dd2d958d27be112d8401d8b05746eea402a95e0 --- /dev/null +++ b/interpro_active_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ec4bcba05ee3a62a6e22dc49f3cfbc32b5836caef5a1cb56e3262e2c7b7fa2e5 +size 142432 diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..25984660aaac6b38f60129e303b19c31651090af --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c2c06a8e07f8d0b8c18423a50199c0a4f64864cfb63838d00f35bb385b51bdac +size 91003 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2109cf98d67a0a24d693e3ed8d04352ab258ce21 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Cysteine peptidase, cysteine active site [IPR000169] 3 7 2.454565576623616 0.0141054934786972 1.9927184466019416 4.106796116504855 -0.4055096631049736 0.4078826502023353 1.2157723137108922 1.0442874781746152 1.1544656254210668 0.3023405414752508 0.0001491979893058 1.7811480551971096e-05 0.0001343549216781 9.549361773523036e-05 0.0013678067399173 +Tyrosine-protein kinase, active site [IPR008266] 5 8 2.1863750752917324 0.0287881755976573 1.966019417475728 4.424757281553398 -0.1200516463743167 0.6230089636210521 1.361328120641804 1.7240921881171525 0.7701660211075021 0.2916799688715877 0.0547124941924187 1.0 1.0 0.3670688568616856 0.1125319425951153 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ae944a531bb31c32ccd6698befd9f49e5a6cc7b7 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 60, + "title": "Average number of proteins per term", + "value": 3.0833333333333335 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5b49e0c60b9c86c1b13e6d925a94c4e418ef4b1d --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..05bfba6ec2452c01dc5125e898aff2df1b6f9a6c --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,9 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cysteine peptidase, cysteine active site [IPR000169] 0.903234098546114 2.4545655766236156 0.0141054934786972 0.5735905685847447 0.0846329608721836 7 P07711,P53634,P07858 3 +Cysteine peptidase, histidine active site [IPR025660] 0.9588820209621014 2.207245971045987 0.027296879674961 0.8099715863867478 0.0959605853255244 4 P07711,P53634,P07858 3 +Tyrosine-protein kinase, active site [IPR008266] 0.8198355662143418 2.1863750752917324 0.0287881755976573 0.8266843919311778 0.0959605853255244 8 P29317,P23458,Q15375,P00533,P07947 5 +Cysteine peptidase, asparagine active site [IPR025661] 0.990059108006448 1.733471643888205 0.083011873261201 0.9944814784239084 0.19382837455086 3 P07711,P07858 2 +Serine carboxypeptidase, serine active site [IPR018202] 0.9793121977431484 1.6930116933471524 0.090453241457068 0.996615443041714 0.19382837455086 3 Q9HB40,P10619 2 +Protein-tyrosine phosphatase, active site [IPR016130] 0.649750985339087 1.4964508307385205 0.1345362119096613 0.9998282352366452 0.2522553973306151 9 Q9NYA4,P10586,Q13614 3 +Peptidase S16, active site [IPR008268] 0.5401557883427216 0.1970549451724033 0.8437845406012432 1.0 0.9040548649299034 2 P36776 1 +Adenosine/AMP deaminase active site [IPR006650] 0.4023636852000979 0.0638263690741692 0.949108481577531 1.0 0.981967429044786 2 Q01433 1 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d4fa16a9491492a164493d4fea06c5b9a403e38a --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 18 (GH18) active site [IPR001579]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["AAK1", "ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "AMPD2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP8", "CDC42BPB", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK7", "CDK9", "CHEK1", "CHEK2", "CHUK", "CIT", "CKB", "CKMT1A*", "CLK2", "CLK3", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTBS", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "DLD", "DNMT1", "DUSP3", "EGFR", "EIF2AK2", "EPHA2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "JAK1", "LDHA", "LDHB", "LONP1", "LONP2", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MARK2", "MDH1", "MDH2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "NME3", "NME4", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKACB", "PRKCA", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "WNK2", "YES1"], "leading_proteins": ["AMPD2", "CTSA", "CTSB", "CTSC", "CTSL", "EGFR", "EPHA2", "EPHA7", "JAK1", "LONP1", "MTMR2", "MTMR4", "PTPRF", "SCPEP1", "YES1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..231e881f172ea5bcda422ccd15300d44886aef2d --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f5fddddb63b5157daeff4a56437c1a4765fc698c2744679e352fd14874c21774 +size 139785 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..af03fc7fccdbdfff3d585d41b6924d885036562f --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5805e5271e00b3af251530e2a0db284e6df01c4208d19ae3a9ba8895cfb44f2a +size 83477 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e9a6b5eca6cfad8bd2c177b32ee71147865d7460 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 34, + "title": "Average number of proteins per term", + "value": 4.9411764705882355 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2a0143a6b5baadeb44006775cf21192dfc99c9c9 --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..382c01e3c3824f51d7e5b5b76bed886772ef50b5 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Beta tubulin, autoregulation binding site [IPR013838] 0.7337477658983325 1.3110557913124314 0.1898389151782589 0.9992211983391336 0.6043633634168663 4 P07437,Q9BVA1 2 +EF-Hand 1, calcium-binding site [IPR018247] 0.4261648524050421 1.0967180668063998 0.2727646561647563 0.9999801870457402 0.6286426971532272 39 Q14257,Q9H4M9,P43304,Q15293,P80303,O43852,Q9NWM8,P0DP25,P31949,Q9H223,Q9Y680,Q02818 12 +Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917] 0.6604888530754729 0.4989861126623894 0.6177891674696956 0.9999999999999936 0.7764261781645709 2 O75600 1 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d6e48a2b9222882c1c1831a4152dadf683f5d944 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Aryldialkylphosphatase, zinc-binding site [IPR017947]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Legume lectin, beta chain, Mn/Ca-binding site [IPR019825]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARAF", "ARG2", "AURKA", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC42BPB", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK7", "CDK9", "CETN2", "CHEK1", "CHUK", "CIT", "CLK2", "CLK3", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EGFR", "EHD1", "EHD4", "EIF2AK2", "EPHA2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "HK1", "HK2", "HMBS", "IDE", "IGF1R", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "ITSN2", "JAK1", "LETM1", "LRP2", "MACF1", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PDP1", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKAA2", "PRKACA", "PRKACB", "PRKCA", "PRKCD", "PRKCSH", "PSAT1", "PTER", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK3", "STK4", "TKT", "TTK", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "USP32", "VRK1", "YES1"], "leading_proteins": ["CALM3", "CALU", "EHD1", "EHD4", "FKBP14", "FKBP7", "GCAT", "GPD2", "NUCB1", "NUCB2", "RCN1", "RCN2", "S100A11", "TUBB", "TUBB2B"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ca3344629b73cdf3f937fdbab8c27cd57dd63685 --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "EGF-like calcium-binding, conserved site [IPR018097]", "1": "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "2": "Guanylate kinase, conserved site [IPR020590]"} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/plot_0.png b/interpro_conserved_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..728d079965764bb0692549e226480499fc30c510 --- /dev/null +++ b/interpro_conserved_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:025b47a7730b4499b316deb0a1b84807ba0cff5e6aa79d54c870b1e2db1710a6 +size 196441 diff --git a/interpro_conserved_site/advanced/plot_1.png b/interpro_conserved_site/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..4761b66f0be089b72af79f03ef8f106d1d1049f6 --- /dev/null +++ b/interpro_conserved_site/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4ff644bba7ebd5625cafc3dae2aae74bde658db6d13249ea949eb28d585cdb81 +size 194372 diff --git a/interpro_conserved_site/advanced/plot_2.png b/interpro_conserved_site/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..cca9f83169c7d1a98b7b054ed58e6b104f4b3af4 --- /dev/null +++ b/interpro_conserved_site/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f1979c6595256e3b952a60d50a525bb494f9199f0d4007d11d9da321d33937ab +size 189849 diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ca3344629b73cdf3f937fdbab8c27cd57dd63685 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EGF-like calcium-binding, conserved site [IPR018097]", "1": "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "2": "Guanylate kinase, conserved site [IPR020590]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..67ff4f39b9ec2cc59d628366ffe3a38a77ae12be --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c1cbb2ebf8a9f351cca5a063b17358af99dec4cace382eb13a831a5424151fb5 +size 145335 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..fc15d6a94b88e787c510f7e06b9d32fd3d553354 --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0547752bc973966fd183cb5eab210795e8ba61fd7330bb8c886e95861d621455 +size 144037 diff --git a/interpro_conserved_site/basic/plot_2.png b/interpro_conserved_site/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..bebb8795cc0c75fbe552b5902e5aa730a18cee31 --- /dev/null +++ b/interpro_conserved_site/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4a7561f6fb3fa09188a1387c5b3c3a27bdc099aeb92db9b1bbac65d2c00b1861 +size 140156 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..a0d8ea99f1e258debd4072fe62206da06592c338 --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2174e1465396c20ba0724bb00564c40f3bfc32e29820da639dc0f7e8e40f1dff +size 103756 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a658197d7e4ee3cfd7246f9ffeba007a84b02c0f --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +EGF-like calcium-binding, conserved site [IPR018097] 8 9 2.77416866159014 0.0055342977658552 1.1703703703703705 2.466666666666667 -0.1373915694631231 0.3902853831950666 1.067180945982341 1.5160051467387146 1.437469353479462 0.3143260829565273 4.383365728727184e-07 0.1665759675679584 0.0004155585626268 1.6510644959116593e-07 5.0413761780603096e-05 +Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415] 5 6 2.5516565782471137 0.0107212137866889 1.062730627306273 1.845018450184502 -0.374757291558179 0.2572252390798428 0.9906082579891434 1.2202031996221276 1.9499632968198624 0.2932843562524823 3.587650196088784e-06 0.0802348466038066 4.180168207037102e-07 1.837861939916845e-06 9.825976589410204e-05 +Syntaxin/epimorphin, conserved site [IPR006012] 3 5 2.010155874905289 0.0444146938838556 2.592233009708738 5.847087378640777 0.9961908981999794 0.2839139128702306 1.4759357288864456 1.4239341993278547 1.138258151200134 0.2914162845337057 0.0003096916980164 1.0 1.0 0.0033170374819039 0.0027426851014433 +Cadherin conserved site [IPR020894] 3 5 1.9858496000853636 0.0470500264025308 1.555825242718447 3.0558252427184467 -0.2693089236279177 0.4378099575304214 1.0377767725547085 1.0517161419538543 1.2797396443463749 0.3315735399503712 0.0118457633601407 1.0 0.1596960736798767 0.0086586519898169 0.0096830476876922 +Guanylate kinase, conserved site [IPR020590] 5 6 1.975273626263949 0.0482371045197085 2.3980582524271843 5.25 0.6064346340666176 0.4240795168052628 1.6195996498310523 1.4740884957165508 0.9685287933135084 0.3034897017004088 1.0 1.0 1.0 1.0 0.0139360561882317 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..00dc09fef0a26fd433f0e43a7cfe557f361dba43 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 296, + "title": "Average number of proteins per term", + "value": 2.918918918918919 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8baaa59a7b2af18f66688455f26b45f06b61ea44 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bca2e7821d5679200276ecf2ed9e8fffb35b380d --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,39 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EGF-like calcium-binding, conserved site [IPR018097] 0.9418729817007612 2.77416866159014 0.0055342977658552 0.8065433734762143 0.1905708099392817 9 P48960,P01130,Q14517,P14543,O94813,Q07954,P98164,P98155 8 +Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415] 0.9688088195751524 2.5516565782471137 0.0107212137866889 0.958853385737268 0.1905708099392817 6 P01130,Q9NPF0,Q92673,P98164,P98155 5 +Sulfatase, conserved site [IPR024607] 0.9478634775597896 2.1648146177806 0.0304018849114293 0.9998925610601078 0.249971053716197 4 P34059,P15289,P15586 3 +Syntaxin/epimorphin, conserved site [IPR006012] 0.8572790385922817 2.0101558749052892 0.0444146938838556 0.9999985553552512 0.2683010079514546 5 O43752,Q86Y82,Q9P2W9 3 +Cadherin conserved site [IPR020894] 0.8512243100370585 1.9858496000853632 0.0470500264025308 0.9999993621033842 0.274580441112187 5 Q14574,Q14517,O60245 3 +Guanylate kinase, conserved site [IPR020590] 0.8238773863941808 1.975273626263949 0.0482371045197085 0.9999995589215278 0.274580441112187 6 Q9NZW5,Q00013,Q12959,Q14168,O14936 5 +Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744] 0.9863013698630148 1.7608645874052056 0.0782613249216437 0.9999999999665872 0.3073515761827814 2 P05067 1 +Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745] 0.9863013698630148 1.7608645874052056 0.0782613249216437 0.9999999999665872 0.3073515761827814 2 P05067 1 +Proteinase inhibitor I2, Kunitz, conserved site [IPR020901] 0.9863013698630148 1.7608645874052056 0.0782613249216437 0.9999999999665872 0.3073515761827814 2 P05067 1 +C-type lectin, conserved site [IPR018378] 0.9830781627719598 1.7477195835080035 0.0805125960413475 0.9999999999837986 0.3073515761827814 2 Q5KU26 1 +Tetraspanin, conserved site [IPR018503] 0.9779747515444532 1.7268958823386922 0.0841863640804914 0.9999999999950466 0.3073515761827814 2 O60637 1 +Lysosome-associated membrane glycoprotein, conserved site [IPR018134] 0.9766317485898496 1.7214138791954725 0.0851757475008034 0.9999999999964028 0.3073515761827814 2 P13473 1 +Glycoside hydrolase, family 29, conserved site [IPR018526] 0.9755573462261644 1.7170276793812491 0.0859741147122581 0.999999999997222 0.3073515761827814 2 Q9BTY2 1 +Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.9642665233745292 1.6362598125345986 0.1017852230537614 0.999999999999984 0.3221279139440353 3 P55899,P04439 2 +Thioredoxin, conserved site [IPR017937] 0.6363200309104422 1.6327618353728484 0.102519096655739 0.9999999999999876 0.3221279139440353 12 O43396,O95881,Q8IXB1,Q9H1E5 4 +Tyrosine-protein kinase, receptor class V, conserved site [IPR001426] 0.946011281224822 1.5962427046369323 0.1104346165715912 0.9999999999999992 0.3301883485372829 2 Q15375 1 +EGF-like, conserved site [IPR013032] 0.940102068224554 1.5720600910264726 0.1159366158503294 1.0 0.3331770707931797 2 O94813 1 +Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184] 0.9223744292237442 1.499501559236722 0.1337435645095293 1.0 0.3665564360631543 2 P17301 1 +Sugar transporter, conserved site [IPR005829] 0.9167338168144048 1.476419275703749 0.1398313712263577 1.0 0.3728836566036205 2 Q7L0J3 1 +Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.770835457675008 1.4617644998814583 0.1438057553600191 1.0 0.3740914456661736 4 Q8N4Q0,Q8WWV3 2 +Glycoside hydrolase, family 35, conserved site [IPR019801] 0.8957829707225484 1.390759900093303 0.1642982467232392 1.0 0.40526900858399 2 P16278 1 +Tubulin, conserved site [IPR017975] 0.7337477658983322 1.3110557913124314 0.1898389151782589 1.0 0.4568481210793873 4 P07437,Q9BVA1 2 +Dynamin, GTPase region, conserved site [IPR019762] 0.7565824825362668 0.8591042208626387 0.3902830188367772 1.0 0.6526766868682827 3 Q05193,O00429 2 +Calreticulin/calnexin, conserved site [IPR018124] 0.6874369710235905 0.6203579261243112 0.5350221660092507 1.0 0.7763066722487167 3 O14967 1 +DnaJ domain, conserved site [IPR018253] 0.4222442065958056 0.5479556643518221 0.583722345888432 1.0 0.8225936352563066 13 Q99543,Q9NVH1,Q96KC8 3 +Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.4590189225130934 0.3960639171520987 0.6920578762548311 1.0 0.8843331714779885 5 P48735 1 +ABC transporter-like, conserved site [IPR017871] 0.3560563368061407 0.2361390969098127 0.813324736694278 1.0 0.9417097676352492 14 P08183,Q03519,P33527,O14678 4 +Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.556809024979853 0.228327232509213 0.8193918551623964 1.0 0.9417097676352492 2 P29692 1 +Aminotransferase, class IV, conserved site [IPR018300] 0.5549288208433996 0.2246153461193461 0.822278525450798 1.0 0.9417097676352492 2 O15382 1 +Mrp, conserved site [IPR000808] 0.5490196078431401 0.2132492100464517 0.8311325868244754 1.0 0.9417097676352492 2 Q8TB37 1 +Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.5338527673293838 0.2092828887825556 0.8342274087881723 1.0 0.9417097676352492 3 Q9BXS5,Q96CW1 2 +Procollagen-lysine 5-dioxygenase, conserved site [IPR001006] 0.5314347125201415 0.2047099708791874 0.8377987297491756 1.0 0.9417097676352492 3 Q02809,O00469 2 +Serpin, conserved site [IPR023795] 0.5118216012896196 0.170145617457151 0.8648956189617467 1.0 0.9517067033928516 3 P50454,P30740 2 +Oxysterol-binding protein, conserved site [IPR018494] 0.359651445991032 0.1647770986164277 0.8691194302795286 1.0 0.9528124124545944 8 Q9BXW6 1 +Ubiquitin conserved site [IPR019954] 0.4758079859254815 0.1183845519376372 0.9057629654682882 1.0 0.9820726658557264 3 P46379 1 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.4723267060719944 0.1141686218170487 0.9091041253969938 1.0 0.9820978872901832 3 O15347,P26583 2 +Heat shock protein Hsp90, conserved site [IPR019805] 0.4591617409994527 0.0994327826005489 0.9207946549767818 1.0 0.9911098831750088 3 P14625,P08238 2 +Dynein light chain, type 1/2, conserved site [IPR019763] 0.4512489927477829 0.088853822111738 0.92919808294478 1.0 0.9955124257838426 2 P63167 1 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6acd1267a0e25680fac5a89b44d97de4c42a5fa0 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3'5'-cyclic nucleotide phosphodiesterase, conserved site [IPR023174]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AF4 interaction motif [IPR043639]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Adenylyl cyclase class-4/guanylyl cyclase, conserved site [IPR018297]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-2-macroglobulin, conserved site [IPR019742]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site [IPR020611]", "Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site [IPR014783]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GPCR, family 2, secretin-like, conserved site [IPR017983]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kank N-terminal motif [IPR021939]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADCY3", "ADGRE5", "ADH5", "ADK", "ADSL", "AFF4", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARSA", "ATAD1", "ATAD2", "ATM", "ATP5C1", "ATP5O", "ATP7A", "BAG6", "BAK1", "BARD1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT1", "BCAT2", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX4", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD320", "CDC40", "CDH2", "CDKAL1", "CDX2", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CHD5", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DBI", "DCAF13", "DCAF7", "DCP2", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX35", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DMD", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FAT1", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FOXK2", "FTL", "FUCA1", "FUCA2", "GAA", "GALK1", "GALNS", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IGF1R", "ILVBL", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IQGAP3", "ISCA2", "ITGA2", "ITGAV", "IVD", "KANK2", "KATNA1", "KDM2A", "KDM5A", "KDM5B", "KDSR", "KIF11", "KIF14", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRP2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGA", "MGST2", "MID1", "MIF", "MKRN2", "MOCS1", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NF2", "NID1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSD3", "NSF", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PAM", "PBRM1", "PCDH7", "PCK2", "PCNA", "PDE8A", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF2", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RELA", "RIDA", "RIOK2", "RNF14", "RNF20", "RNF31", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCAP", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SGSH", "SHPRH", "SLC1A5", "SLC27A2", "SLC27A4", "SLC2A1", "SLC4A2", "SLC5A6", "SLIT2", "SMARCA4", "SMG1", "SMU1", "SNRNP40", "SNU13", "SORD", "SORL1", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STX12", "STX18", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE1", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TM7SF2", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TRAF2", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM32", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP32", "USP33", "USP34", "USP36", "USP38", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VLDLR", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR48", "WDR5", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCC1", "ABCD4", "ADGRE5", "AP1M1", "AP2M1", "APP", "ARSA", "BAG6", "BCAT2", "CASK", "CD320", "CLGN", "COLEC12", "DLG1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNM1", "DNM1L", "DSC3", "DYNLL1", "EEF1D", "EPHA7", "FAT1", "FCGRT", "FUCA2", "GALNS", "GLB1", "GNS", "HLA-A", "HMGB2", "HMGB3", "HSP90AB1", "HSP90B1", "IDH2", "ITGA2", "LAMP2", "LDLR", "LRP1", "LRP2", "MPP1", "MPP2", "MPP6", "NID1", "NUBPL", "OSBPL1A", "PCDH7", "PLOD1", "PLOD2", "RTN4IP1", "SERPINB1", "SERPINH1", "SLIT2", "SORL1", "STX12", "STX18", "STX6", "SV2A", "TAP2", "TMX4", "TSPAN3", "TUBB", "TUBB2B", "TXNDC12", "TXNL1", "VLDLR", "ZADH2"]} \ No newline at end of file diff --git a/interpro_domain/advanced/idx2term.json b/interpro_domain/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..893c8329514d1dc64dfc5f0d81fd8ae799d1d67f --- /dev/null +++ b/interpro_domain/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Immunoglobulin-like domain [IPR007110]", "1": "EGF-like domain [IPR000742]", "2": "Immunoglobulin subtype [IPR003599]", "3": "Immunoglobulin subtype 2 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0000000000000000000000000000000000000000..e9a933399429fa888389e98fba69b1090e4be4d5 --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,18 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Immunoglobulin-like domain [IPR007110] 21 26 3.3588400659198303 0.000782703520896 4.480582524271845 12.427184466019416 0.4075261998509777 0.4433674298264088 2.6479725987944898 3.173316973839475 1.1756568118942026 0.3233613924696422 5.28041372537348e-05 0.4279811411777856 0.2961867551178612 0.0003915145463048 1.7983454885691126e-06 +EGF-like domain [IPR000742] 11 14 3.065689218138707 0.0021716891599412 1.812807881773399 3.940886699507389 -0.2515571357977262 0.397990648527913 1.5407225921455587 2.4527963737747185 1.3250723622342764 0.3076599741691995 8.074842210268027e-07 0.312708212996757 0.0060698672163979 1.850392099010424e-06 6.405197101049468e-05 +Immunoglobulin subtype [IPR003599] 16 21 2.9643317713191406 0.0030334104971692 2.9684466019417477 8.483009708737864 0.1381371967634491 0.4928258967784709 2.271921156707309 2.9216637549507847 1.0756254869730633 0.312999744433737 0.0160063591153178 1.0 1.0 0.0851257395407892 0.000224943106111 +Immunoglobulin subtype 2 [IPR003598] 14 19 2.7812414753082204 0.0054151441463126 2.8106796116504853 8.04126213592233 0.1764352420775828 0.5005828106358552 2.0581551085254395 2.677802743524345 1.0491539805619012 0.3137632145774063 0.0366493043441931 1.0 1.0 0.0814773755217055 8.917551346587106e-05 +EGF-like calcium-binding domain [IPR001881] 8 9 2.77416866159014 0.0055342977658552 1.1703703703703705 2.466666666666667 -0.1373915694631231 0.3902853831950666 1.067180945982341 1.5160051467387146 1.437469353479462 0.3143260829565273 1.395195336704849e-06 0.1868885334554594 0.0006788789579845 5.32603095196751e-07 0.0001455639700759 +Fibronectin type III [IPR003961] 7 13 2.7304331784133704 0.0063251154261654 2.2257281553398056 5.589805825242719 -0.3209057323720775 0.5133796044193292 1.3812257831232946 2.0501463270450144 0.914078257814304 0.3019356379166223 0.0029914489537413 0.295480255529908 0.1487873266068847 0.0015612560180347 0.0209555118054096 +Target SNARE coiled-coil homology domain [IPR000727] 8 11 2.4521145073852963 0.0142019459975824 3.5024271844660193 8.266990291262136 0.5942034778060385 0.4012381903331891 1.9023475359698396 2.183694577914796 1.0582363712887182 0.3038263160802639 0.0042428886577654 1.0 1.0 0.0215683584236732 1.493712328300715e-05 +Immunoglobulin V-set domain [IPR013106] 8 9 2.438113943816722 0.0147641194198608 1.8814814814814815 3.639506172839506 -0.1240957684542258 0.411362008796823 1.3951513136318474 1.5958030613003984 1.3078070990153907 0.3212718057023477 0.0020491830728424 1.0 1.0 0.0479498850625808 0.0001705037636277 +MHC class I-like antigen recognition-like [IPR011161] 4 5 2.4316198207856634 0.0150314756163449 1.6286407766990292 3.3519417475728157 0.7088257141352072 0.3792248400111384 0.978137271268229 0.8617667089672962 1.1217132539816763 0.2987888107271844 2.296556417175484e-05 0.066549445548378 0.0077184558590264 1.31526437712885e-05 0.0003637398802397 +Tyrosine-protein kinase, catalytic domain [IPR020635] 4 7 2.236668091595155 0.0253080409545809 1.4549878345498783 3.347931873479318 -0.1073075978789242 0.5843186680309347 1.167188560646926 1.5977826348276636 0.9800932582276456 0.3173028330603973 0.0305551934453896 1.0 1.0 0.2871762535363917 0.0601700233302374 +Immunoglobulin C1-set [IPR003597] 3 5 2.201991540247724 0.0276659060507333 1.5364077669902914 3.2645631067961167 0.6739064474228705 0.388919959347808 0.9507966556146606 0.908645932409072 1.1616974926444357 0.3094128568625329 0.0014768241824232 0.0892490045576324 0.014058804472369 0.000963248429344 0.0017273216459823 +CBS domain [IPR000644] 3 7 2.1946581986029696 0.0281881253935281 2.308252427184466 5.975728155339806 0.471037738888513 0.4502961978559324 1.3346138143177957 1.192367801747502 0.984645289709199 0.3089170588327933 0.0036004577965194 0.0573151884822011 0.1094892401774078 0.0025975272437437 0.0019736987849612 +Cadherin-like [IPR002126] 4 6 2.152377400728627 0.0313676421525568 1.5898058252427183 3.1310679611650487 -0.2612861714701764 0.4372142450358497 1.076759324040342 1.1605597181786682 1.2840907797021492 0.3325457904266107 0.002185329286291 1.0 0.0170518298819148 0.0014320459890063 0.0027898710574492 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 5 10 2.116251098265392 0.0343234574091513 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.1184088205118859 1.0 1.0 0.4160065505344545 0.0034687949642114 +CD80-like, immunoglobulin C2-set [IPR013162] 4 5 2.019767713890178 0.0434074875656562 1.0759878419452888 2.048632218844985 -0.1756221563179299 0.3952566282953844 0.8976502658898853 1.0213851440359738 1.5016782300234648 0.3371068272453545 0.2400848710653836 1.0 1.0 1.0 0.0009048869233579 +Immunoglobulin I-set [IPR013098] 7 11 1.990793067947068 0.0465036417873312 1.483009708737864 3.5436893203883497 -0.0396549694488073 0.564695829059301 1.2056512037685103 1.5596657535194778 0.9626777574921488 0.3192014691096427 0.1659533218790633 1.0 1.0 0.1300529274831162 0.0387569851109487 +Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 5 13 1.9711360289442437 0.0487083186436616 2.966019417475728 7.271844660194175 -0.1579772346511897 0.6203489297954423 2.027435770979738 2.327314276770509 0.7245114158691095 0.2792938885446872 0.1305593967839345 1.0 1.0 0.5217398143434403 0.269520772440518 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1df9ec8bbea6e44f9b6156959af034cbe78c8bd3 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 2967, + "title": "Average number of proteins per term", + "value": 2.2949106841927875 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0134f6898375cb3f8b5a03463275372a9b2d4748 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..82563a99c8f4d74f68c04374817f9f9b83e134fe --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,302 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Immunoglobulin-like domain [IPR007110] 0.8121169233628129 3.3588400659198303 0.000782703520896 0.9020394713085722 0.2126069400692648 26 P01889,Q13740,Q13308,Q9Y624,P35613,P55899,O94898,Q7KYR7,Q5ZPR3,P13591,P04439,Q9BY67,Q08722,P10586,Q92859,Q96J84,P10321,P43121,P78310,Q92692,Q9Y6N7 21 +EGF-like domain [IPR000742] 0.9037939235570642 3.065689218138707 0.0021716891599412 0.998420123210726 0.2126069400692648 14 Q04721,Q14517,P01130,P48960,Q08431,P14543,O94813,O75882,Q07954,P98164,P98155 11 +Immunoglobulin subtype [IPR003599] 0.7842901359694869 2.9643317713191406 0.0030334104971692 0.9998782824250112 0.2126069400692648 21 P35613,P13591,Q92859,Q96J84,Q9BY67,Q13740,P43121,P10586,O94898,Q13308,Q92692,P78310,Q7KYR7,Q5ZPR3,Q9Y624,Q9Y6N7 16 +Immunoglobulin subtype 2 [IPR003598] 0.7720143973100798 2.7812414753082204 0.0054151441463126 0.9999998992266806 0.2126069400692648 19 P35613,P13591,Q92859,Q96J84,Q9BY67,Q13740,P43121,P10586,O94898,Q13308,P78310,Q5ZPR3,Q9Y624,Q9Y6N7 14 +EGF-like calcium-binding domain [IPR001881] 0.9418729817007612 2.77416866159014 0.0055342977658552 0.999999929373974 0.2126069400692648 9 P48960,P01130,Q14517,P14543,O94813,Q07954,P98164,P98155 8 +Fibronectin type III [IPR003961] 0.8494893826869905 2.7304331784133704 0.0063251154261654 0.999999993333824 0.2126069400692648 13 Q92859,P29317,P15260,P10586,Q92673,Q15375,Q9Y6N7 7 +Target SNARE coiled-coil homology domain [IPR000727] 0.8256146723532733 2.4521145073852963 0.0142019459975824 1.0 0.2126069400692648 11 O43752,Q86Y82,O00161,Q9UNK0,O15400,O95721,Q5SQN1,Q9UEU0 8 +Immunoglobulin V-set domain [IPR013106] 0.860602798708303 2.438113943816722 0.0147641194198608 1.0 0.2126069400692648 9 Q9BY67,P43121,Q92692,P78310,Q7KYR7,Q5ZPR3,Q9Y624,Q9Y6N7 8 +MHC class I-like antigen recognition-like [IPR011161] 0.9647849462365604 2.4316198207856634 0.0150314756163449 1.0 0.2126069400692648 5 P10321,P55899,Q9UNN8,P04439 4 +Tyrosine-protein kinase, catalytic domain [IPR020635] 0.8498547721114708 2.236668091595155 0.0253080409545809 1.0 0.2210641895559799 7 P23458,Q15375,P29317,P00533 4 +Peptidase C1A, papain C-terminal [IPR000668] 0.9588820209621014 2.207245971045987 0.027296879674961 1.0 0.2214831740106085 4 P07711,P53634,P07858 3 +Immunoglobulin C1-set [IPR003597] 0.9056005040115792 2.201991540247724 0.0276659060507333 1.0 0.2214831740106085 5 P10321,P55899,P04439 3 +CBS domain [IPR000644] 0.839724497917176 2.1946581986029696 0.0281881253935281 1.0 0.2214831740106085 7 P51798,P51790,Q8NE01 3 +Sulfatase, N-terminal [IPR000917] 0.9478634775597896 2.1648146177806 0.0304018849114293 1.0 0.2255059813305273 4 P34059,P15289,P15586 3 +Cadherin-like [IPR002126] 0.8673972088785544 2.152377400728627 0.0313676421525568 1.0 0.2302754460030595 6 Q14574,Q14517,Q9BQT9,O60245 4 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.7690897818269417 2.116251098265392 0.0343234574091513 1.0 0.2384957801708477 10 Q9H7F0,Q04656,P98194,Q9HD20,Q9NQ11 5 +CD80-like, immunoglobulin C2-set [IPR013162] 0.8596774193548427 2.019767713890178 0.0434074875656562 1.0 0.2579189260964564 5 Q9BY67,P43121,Q92692,Q96J84 4 +Immunoglobulin I-set [IPR013098] 0.7251458506724541 1.990793067947068 0.0465036417873312 1.0 0.2597870563970735 11 P13591,Q92859,Q96J84,P10586,O94898,Q13308,Q9Y6N7 7 +Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 0.6907295085554557 1.9711360289442432 0.0487083186436616 1.0 0.2646702048284577 13 P29317,P23458,Q15375,P00533,P07947 5 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.8949207202364886 1.958525817832468 0.0501683445988636 1.0 0.2646702048284577 4 Q96CP7,Q15629,Q96G23 3 +PSI domain [IPR016201] 0.8868583714055335 1.9267744418702557 0.0540077459514312 1.0 0.2718654819222417 4 O75882,P51805,P05556 3 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.7718201378625772 1.907660477598544 0.0564351130354094 1.0 0.2763979921572478 7 Q9NZW5,Q00013,Q12959,Q14168,O14936 5 +Guanylate kinase-like domain [IPR008144] 0.7718201378625772 1.907660477598544 0.0564351130354094 1.0 0.2763979921572478 7 Q9NZW5,Q00013,Q12959,Q14168,O14936 5 +Cyclic nucleotide-binding domain [IPR000595] 0.8284723275051984 1.8939951790537757 0.0582256497753497 1.0 0.2763979921572478 5 P10644 1 +L27 domain [IPR004172] 0.8236559139785015 1.8744474356041063 0.0608687806135297 1.0 0.2841351823257951 5 Q12959,Q14168,O14936,Q9NZW5 4 +Major facilitator superfamily domain [IPR020846] 0.8233242405385486 1.8731000182763344 0.0610545748481783 1.0 0.2841351823257951 5 Q8NHS3,Q7L0J3 2 +Dynamin, N-terminal [IPR045063] 0.7394264100912417 1.8369086548517048 0.0662233814019945 1.0 0.2932608546562953 8 Q9H4M9,O00429,Q05193,O95140,Q9H223,Q8IWA4 6 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.7394264100912417 1.8369086548517048 0.0662233814019945 1.0 0.2932608546562953 8 Q9H4M9,O00429,Q05193,O95140,Q9H223,Q8IWA4 6 +MRH domain [IPR044865] 0.8078729026098206 1.81014692148064 0.0702730062335428 1.0 0.3052708777378061 5 P11717 1 +BTB/POZ domain [IPR000210] 0.7481181156889343 1.8053164481381545 0.0710251772190799 1.0 0.3080872818845179 7 Q96CX2,Q14145,Q9P2R3,Q08380 4 +Cysteine-rich flanking region, C-terminal [IPR000483] 0.853533996237558 1.7946598988037057 0.0727079033882796 1.0 0.3135528333619557 4 O94898,O94813,Q13641 3 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.7421513487746999 1.779382196023427 0.0751771233550455 1.0 0.320936007186216 7 Q8WUJ1,O43169 2 +MD-2-related lipid-recognition domain [IPR003172] 0.9889873757722272 1.7718144992092664 0.0764253549276403 1.0 0.3220140696320572 2 P17900 1 +Glycoside hydrolase family 20, catalytic domain [IPR015883] 0.9871071716357774 1.7641499753585472 0.0777067323945877 1.0 0.3220140696320572 2 P06865 1 +Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019] 0.9871071716357774 1.7641499753585472 0.0777067323945877 1.0 0.3220140696320572 2 P06865 1 +Pancreatic trypsin inhibitor Kunitz domain [IPR002223] 0.9863013698630148 1.7608645874052056 0.0782613249216437 1.0 0.3220140696320572 2 P05067 1 +Amyloidogenic glycoprotein, E2 domain [IPR024329] 0.9863013698630148 1.7608645874052056 0.0782613249216437 1.0 0.3220140696320572 2 P05067 1 +Amyloidogenic glycoprotein, heparin-binding [IPR015849] 0.9863013698630148 1.7608645874052056 0.0782613249216437 1.0 0.3220140696320572 2 P05067 1 +Beta-amyloid precursor protein C-terminal [IPR019543] 0.9863013698630148 1.7608645874052056 0.0782613249216437 1.0 0.3220140696320572 2 P05067 1 +Amyloidogenic glycoprotein, extracellular [IPR008154] 0.9863013698630148 1.7608645874052056 0.0782613249216437 1.0 0.3220140696320572 2 P05067 1 +Amyloidogenic glycoprotein, copper-binding [IPR011178] 0.9863013698630148 1.7608645874052056 0.0782613249216437 1.0 0.3220140696320572 2 P05067 1 +Glycoside hydrolase family 2, catalytic domain [IPR006103] 0.9857641686811708 1.7586741344443233 0.078632873120743 1.0 0.3222427272779622 2 O00462 1 +Choline/carnitine acyltransferase domain [IPR039551] 0.8438251024199097 1.7559189614788706 0.0791022468105016 1.0 0.3234611538635827 4 P23786 1 +CD209-like, C-type lectin-like domain [IPR033989] 0.9830781627719598 1.7477195835080035 0.0805125960413475 1.0 0.3272340718557234 2 Q5KU26 1 +BRICHOS domain [IPR007084] 0.9803921568627472 1.736761335826979 0.0824293062957131 1.0 0.3292122980734859 2 Q9Y287 1 +Alpha-L-fucosidase, C-terminal [IPR031919] 0.9755573462261644 1.7170276793812491 0.0859741147122581 1.0 0.3316718473195928 2 Q9BTY2 1 +Sortilin, C-terminal [IPR031777] 0.965350523771155 1.675334403808314 0.0938686388999014 1.0 0.3450630992726206 2 Q92673 1 +VPS10 [IPR006581] 0.965350523771155 1.675334403808314 0.0938686388999014 1.0 0.3450630992726206 2 Q92673 1 +Sortilin, N-terminal [IPR031778] 0.965350523771155 1.675334403808314 0.0938686388999014 1.0 0.3450630992726206 2 Q92673 1 +PA domain [IPR003137] 0.9650819231802328 1.6742366649445746 0.0940840962997893 1.0 0.3450630992726206 2 P02786 1 +L27 domain, C-terminal [IPR014775] 0.8234345606019775 1.6742220247308048 0.0940869724676609 1.0 0.3450630992726206 4 Q14168,O14936,Q9NZW5 3 +Ricin B, lectin domain [IPR000772] 0.7514365967501228 1.673196001168356 0.0942887173190705 1.0 0.3453760793650398 6 Q9UBG0,Q86SF2,Q10472 3 +C-type lectin-like [IPR001304] 0.9682966147232664 1.6514724918407195 0.0986421332070595 1.0 0.3530583535791798 3 Q5KU26,Q9UBG0 2 +Peptidase M14, carboxypeptidase A [IPR000834] 0.9594413107708883 1.651178491111977 0.0987021337109419 1.0 0.3530583535791798 2 O75976 1 +Complement Clr-like EGF domain [IPR026823] 0.9680279419666844 1.6504585568959214 0.0988491829699973 1.0 0.3530583535791798 3 P14543,P98164 2 +Papain-like cysteine endopeptidase [IPR039417] 0.958366908407204 1.6467853137210229 0.0996021810816949 1.0 0.3530583535791798 2 P07711 1 +Cathepsin propeptide inhibitor domain (I29) [IPR013201] 0.958366908407204 1.6467853137210229 0.0996021810816949 1.0 0.3530583535791798 2 P07711 1 +Laminin G domain [IPR001791] 0.957023905452594 1.6412933694807037 0.1007365318125834 1.0 0.3530583535791798 2 O94813 1 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.9642665233745296 1.6362598125345986 0.1017852230537614 1.0 0.3530583535791798 3 P10321,P04439 2 +MHC class I, alpha chain, C-terminal [IPR010579] 0.9642665233745296 1.6362598125345986 0.1017852230537614 1.0 0.3530583535791798 3 P10321,P04439 2 +Sphingomyelin phosphodiesterase, C-terminal domain [IPR045473] 0.954875100725223 1.632505223417715 0.1025730990062128 1.0 0.3530583535791798 2 Q92485 1 +Acid sphingomyelinase/endopolyphosphatase, metallophosphatase domain [IPR041805] 0.954875100725223 1.632505223417715 0.1025730990062128 1.0 0.3530583535791798 2 Q92485 1 +Calcineurin-like phosphoesterase domain, ApaH type [IPR004843] 0.7391448016307662 1.6211124906712076 0.1049935156611372 1.0 0.3539936661234027 6 Q92485,Q6ZT21 2 +Fibronectin type II domain [IPR000562] 0.9572036664611172 1.6095812648840755 0.1074893009815431 1.0 0.3554878556648331 3 P11717 1 +Band 7 domain [IPR001107] 0.6868267767213094 1.6010159423610726 0.1093733881664045 1.0 0.3568678897380813 8 O75955,P27105 2 +Ephrin receptor, transmembrane domain [IPR027936] 0.946011281224822 1.5962427046369323 0.1104346165715912 1.0 0.3584896141880867 2 Q15375 1 +Ephrin receptor ligand binding domain [IPR001090] 0.946011281224822 1.5962427046369323 0.1104346165715912 1.0 0.3584896141880867 2 Q15375 1 +Coagulation factor 5/8 C-terminal domain [IPR000421] 0.9425194735428456 1.5819535237830955 0.1136601807760944 1.0 0.3618951622884394 2 Q08431 1 +CUB domain [IPR000859] 0.9427727028479302 1.5550104782518424 0.1199435738252825 1.0 0.3707006078537638 3 O75882,Q6UXD5 2 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.7213715762301782 1.545428978409839 0.1222425354446881 1.0 0.3751502782224259 6 Q9H7F0,P98194 2 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.7213715762301782 1.545428978409839 0.1222425354446881 1.0 0.3751502782224259 6 Q9H7F0,P98194 2 +Marvel domain [IPR008253] 0.9328498522696792 1.542377015544917 0.1229820035692523 1.0 0.3757853806281893 2 Q16625 1 +Calcium binding and coiled-coil domain-like [IPR012852] 0.929089443996784 1.5269852441190803 0.1267646806575459 1.0 0.3775673700056873 2 Q86VP1 1 +Syntaxin, N-terminal domain [IPR006011] 0.9264034380875644 1.5159913741687352 0.1295215335481558 1.0 0.3825594983631521 2 Q86Y82 1 +CALCOCO1/2, zinc finger UBZ1-type [IPR041641] 0.9293390650188058 1.5041558487307325 0.1325412429524348 1.0 0.3866763695573984 3 Q86VP1,Q13137 2 +SKICH domain [IPR041611] 0.9293390650188058 1.5041558487307325 0.1325412429524348 1.0 0.3866763695573984 3 Q86VP1,Q13137 2 +Integrin alpha-2 [IPR013649] 0.9223744292237442 1.499501559236722 0.1337435645095293 1.0 0.3882751036201305 2 P17301 1 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.916465216223475 1.4753202550216746 0.1401264633814545 1.0 0.3937075917166435 2 Q14011 1 +VHS domain [IPR002014] 0.7738401946459968 1.4739527996954251 0.1404943001075151 1.0 0.3943676333197706 4 Q92783,O14964 2 +Sterile alpha motif domain [IPR001660] 0.618128876478619 1.470704667069113 0.1413710035145559 1.0 0.3957054409695163 11 Q15375 1 +Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.9086757990867588 1.4434559992599192 0.1488920589132942 1.0 0.405792272583646 2 P51114 1 +CNNM, transmembrane domain [IPR002550] 0.9078699973139994 1.4401606526138335 0.1498219524995192 1.0 0.4060918710049523 2 Q8NE01 1 +Ion transporter-like, CBS domain [IPR044751] 0.9078699973139994 1.4401606526138335 0.1498219524995192 1.0 0.4060918710049523 2 Q8NE01 1 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.9059897931775444 1.4324723351227864 0.152008689979594 1.0 0.4103361241825574 2 O60506 1 +FAD dependent oxidoreductase [IPR006076] 0.7633247369326244 1.4312791371656428 0.1523502307261595 1.0 0.4103361241825574 4 Q9H9P8,P43304 2 +Immunoglobulin [IPR013151] 0.9014235831318864 1.4138060446395375 0.1574188582979272 1.0 0.416647415316637 2 P78310 1 +N-acetylgalactosaminyltransferase [IPR045885] 0.7554071214722979 1.3991171176630364 0.1617778653636872 1.0 0.4214357856080341 4 Q86SF2,Q10472 2 +Fragile X-related 1 protein, C-terminal core [IPR022034] 0.9013970983342282 1.3983082084378828 0.1620205339866283 1.0 0.4214357856080341 3 P51116,P51114 2 +Fxr1, tudor domain [IPR041560] 0.9013970983342282 1.3983082084378828 0.1620205339866283 1.0 0.4214357856080341 3 P51116,P51114 2 +Agenet-like domain [IPR008395] 0.9013970983342282 1.3983082084378828 0.1620205339866283 1.0 0.4214357856080341 3 P51116,P51114 2 +Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.9013970983342282 1.3983082084378828 0.1620205339866283 1.0 0.4214357856080341 3 P51116,P51114 2 +Glycosyl hydrolase, family 13, catalytic domain [IPR006047] 0.8960515713134621 1.3918569920269126 0.1639657076523673 1.0 0.4222970960109147 2 P08195 1 +Glycoside hydrolase 35, catalytic domain [IPR031330] 0.8957829707225484 1.390759900093303 0.1642982467232392 1.0 0.4227865550978758 2 P16278 1 +Protein-tyrosine phosphatase, catalytic [IPR003595] 0.639087017742809 1.3825891490500013 0.1667908780931704 1.0 0.4262433551269909 8 P10586,Q9ULE6,Q13614 3 +CARG-binding factor, N-terminal [IPR012956] 0.8906795594950287 1.3699224711289617 0.1707111042944014 1.0 0.4303312204260738 2 Q99729 1 +EH domain-containing protein, N-terminal [IPR031692] 0.8882621541767436 1.3600573527177795 0.1738117753584835 1.0 0.4337254310249123 2 Q9H223 1 +Domain of unknown function DUF5600 [IPR040990] 0.8882621541767436 1.3600573527177795 0.1738117753584835 1.0 0.4337254310249123 2 Q9H223 1 +Glycoside hydrolase family 38, central domain [IPR015341] 0.8871877518130655 1.355674027729966 0.1752029066189044 1.0 0.4342748737997406 2 O00754 1 +Glycoside hydrolase family 38, N-terminal domain [IPR000602] 0.8871877518130655 1.355674027729966 0.1752029066189044 1.0 0.4342748737997406 2 O00754 1 +Glycosyl hydrolase family 38, C-terminal [IPR011682] 0.8871877518130655 1.355674027729966 0.1752029066189044 1.0 0.4342748737997406 2 O00754 1 +Pre-SET domain [IPR007728] 0.889947223778415 1.3549496746694143 0.175433591466954 1.0 0.4343530068775518 3 Q96KQ7 1 +Plexin, cytoplasmic RasGAP domain [IPR013548] 0.8863819500402939 1.35238702588104 0.1762515376629552 1.0 0.4349951765281995 2 P51805 1 +Plexin, TIG domain 1 [IPR041019] 0.8863819500402939 1.35238702588104 0.1762515376629552 1.0 0.4349951765281995 2 P51805 1 +Sema domain [IPR001627] 0.8863819500402939 1.35238702588104 0.1762515376629552 1.0 0.4349951765281995 2 P51805 1 +Fatty acid hydroxylase [IPR006694] 0.8858447488584453 1.3501959305635027 0.1769531431949118 1.0 0.4353399468153428 2 Q15800 1 +BTB/Kelch-associated [IPR011705] 0.8836959441310919 1.3414335217202118 0.1797797400215097 1.0 0.438080353767581 2 Q08380 1 +Zinc finger, CHHC-type [IPR012996] 0.8828586781300367 1.328123206506777 0.1841374081923628 1.0 0.445988318454482 3 P31943,P52597 2 +Tyrosine-specific protein phosphatases domain [IPR000387] 0.61174947033124 1.3169111853837836 0.1878683967270276 1.0 0.450761056263268 9 Q9NYA4,P10586,Q13614 3 +Chromo domain subgroup [IPR017984] 0.7350174684224499 1.3162195198305058 0.1881003739134412 1.0 0.450761056263268 4 O00257,P83916,Q13185 3 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.7337477658983322 1.3110557913124314 0.1898389151782589 1.0 0.4516770243317446 4 P07437,Q9BVA1 2 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.7337477658983322 1.3110557913124314 0.1898389151782589 1.0 0.4516770243317446 4 P07437,Q9BVA1 2 +FAD linked oxidase, N-terminal [IPR006094] 0.8745635240397671 1.304232107226634 0.1921544558000518 1.0 0.4542806935129513 2 Q15392 1 +FAD-binding domain, PCMH-type [IPR016166] 0.8745635240397671 1.304232107226634 0.1921544558000518 1.0 0.4542806935129513 2 Q15392 1 +GRAM domain [IPR004182] 0.719838376926805 1.2544959575383003 0.2096617941478382 1.0 0.4809388224494622 4 Q969T9,Q13614 2 +Leucine-rich repeat N-terminal domain [IPR000372] 0.8533046749059621 1.2165322975394766 0.2237822154132955 1.0 0.4973014062543372 3 O94813,Q13641 2 +RBM1CTR [IPR012604] 0.850389470856844 1.206151858356609 0.2277589424087995 1.0 0.4994993374373643 2 P38159 1 +EH domain [IPR000261] 0.6425437262817197 1.2057496595560464 0.2279140310029888 1.0 0.4994993374373643 6 Q9H223 1 +SLC12A transporter, C-terminal [IPR018491] 0.8495432563138079 1.2023721714693427 0.2292193660914638 1.0 0.4997654204649418 3 Q9BXP2,P55011 2 +Amino acid permease/ SLC12A domain [IPR004841] 0.8495432563138079 1.2023721714693427 0.2292193660914638 1.0 0.4997654204649418 3 Q9BXP2,P55011 2 +Glycosyltransferase 2-like [IPR001173] 0.6395370642186188 1.1927171471553413 0.2329801678267098 1.0 0.5030383403726727 6 Q86SF2,Q9Y673,Q10472 3 +MIT domain [IPR007330] 0.6977591196329185 1.1648335254310522 0.2440863854689512 1.0 0.5132643688423273 4 Q6PHR2 1 +NAD(P)-binding domain [IPR016040] 0.8364726650196426 1.1532696947038823 0.2487997049338 1.0 0.5198989934041757 3 Q8NBZ7 1 +Dynamin, GTPase domain [IPR001401] 0.6938541709332182 1.1490041466681908 0.2505542708015198 1.0 0.5220467145141217 4 Q05193,O00429 2 +Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520] 0.8321246306742057 1.1325663192787887 0.2573964193220364 1.0 0.5299758335381554 2 Q9HCL2 1 +GPAT/DHAPAT, acyltransferase domain [IPR041728] 0.8321246306742057 1.1325663192787887 0.2573964193220364 1.0 0.5299758335381554 2 Q9HCL2 1 +PDZ domain [IPR001478] 0.4484093455049501 1.0923307451075013 0.274687751262259 1.0 0.5484512503331913 28 O14641,Q9NZW5,Q00013,Q07157,Q14168,Q12959,Q13425,O14936,Q5T2T1,O00560,Q8WWI1,Q8NEN9,Q96L92 13 +Myotubularin-like phosphatase domain [IPR010569] 0.8160256996698135 1.0768559151656834 0.2815446406042596 1.0 0.5569569760722894 3 Q9NYA4 1 +Laminin-type EGF domain [IPR002049] 0.8122341227495089 1.0627512242197312 0.2878947842836559 1.0 0.5642446131211662 3 O75882 1 +PTB/PI domain [IPR006020] 0.6718624025799469 1.0601175952090207 0.2890911039841843 1.0 0.5648901650520737 4 O00213,Q92625,Q9Y3P9 3 +SH2 domain [IPR000980] 0.5167177267309578 1.057267408848824 0.2903895629663762 1.0 0.5648901650520737 13 P23458,P07947,O00459,P62993 4 +Prenylcysteine lyase [IPR010795] 0.8127853881278733 1.0553183086056928 0.2912797703895109 1.0 0.5648901650520737 2 Q9UHG3 1 +IPT domain [IPR002909] 0.6692567702595228 1.049623013420768 0.2938914720200203 1.0 0.5659148284278223 4 P51805 1 +Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.8052645715820757 1.0255032247535787 0.305125804609357 1.0 0.578841599920692 2 Q9Y282 1 +Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.8052645715820757 1.0255032247535787 0.305125804609357 1.0 0.578841599920692 2 Q9Y282 1 +Zinc finger C2H2 AKAP95-type [IPR034736] 0.800727648982962 1.0200945868852287 0.3076836037639818 1.0 0.5810930950781249 3 O43823 1 +ABC transporter type 1, transmembrane domain [IPR011527] 0.5382932662962332 1.0139017142767068 0.3106296533057051 1.0 0.5825788408573609 10 P08183,Q03519,P33527,O14678 4 +EF-hand domain [IPR002048] 0.4110942617092107 0.9910286254653116 0.3216716027429036 1.0 0.5901775819360302 47 Q14257,Q9H4M9,P43304,Q15293,P80303,O75071,O43852,Q9NWM8,P0DP25,P31949,Q9H223,Q9Y680,Q02818 13 +Thioredoxin domain [IPR013766] 0.4370859032405911 0.9752656033131876 0.3294285278298166 1.0 0.597806998208603 26 Q9H1E5,O95881,O14530,O43396,Q8IXB1,Q6ZRP7,Q96JJ7,P30048,Q9P2K2,Q9Y2G8,Q14554 11 +Sam68, tyrosine-rich domain [IPR032335] 0.7835079237174446 0.9401191018005248 0.3471564717111881 1.0 0.6166976055860589 2 Q07666 1 +KHDRBS, Qua1 domain [IPR032571] 0.7835079237174446 0.9401191018005248 0.3471564717111881 1.0 0.6166976055860589 2 Q07666 1 +Band 3 cytoplasmic domain [IPR013769] 0.7816277195810032 0.9328081777224108 0.3509190181693884 1.0 0.6204867264055873 2 Q9Y6M7 1 +Bicarbonate transporter, C-terminal [IPR011531] 0.7816277195810032 0.9328081777224108 0.3509190181693884 1.0 0.6204867264055873 2 Q9Y6M7 1 +Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain [IPR045583] 0.7770615095353421 0.9151028190410894 0.3601376551976436 1.0 0.6265570282590474 2 Q93100 1 +GH15-like domain [IPR011613] 0.7770615095353421 0.9151028190410894 0.3601376551976436 1.0 0.6265570282590474 2 Q93100 1 +Zinc finger, RanBP2-type [IPR001876] 0.5275251829757202 0.9140222645859628 0.3607051467654256 1.0 0.6268016072515948 9 P35637,Q92804,Q01844,P52756,P98175 5 +Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.776255707762576 0.9119858459594296 0.3617761685224332 1.0 0.6277133871380464 2 O15460 1 +OCRE domain [IPR041591] 0.7676651341089749 0.8990506078608207 0.3686257050195261 1.0 0.6333019495037255 3 P52756 1 +Hemimethylated DNA-binding domain [IPR011722] 0.7722266988987343 0.8964358474569616 0.3700200288803956 1.0 0.6345950437503663 2 Q9Y2S7 1 +Fzo/mitofusin HR2 domain [IPR006884] 0.771689497716892 0.8943669858335862 0.3711255704013494 1.0 0.6357561012591245 2 Q8IWA4 1 +von Willebrand factor, type A [IPR002035] 0.5318469767518865 0.8842335501032871 0.3765701508120258 1.0 0.6408568767066898 8 O43405 1 +Tyrosine-specific protein phosphatase, PTPase domain [IPR000242] 0.5812099198133567 0.8645925430999971 0.3872624667852904 1.0 0.6491569146621223 5 P10586 1 +HD/PDEase domain [IPR003607] 0.7636314799892572 0.8634657833607358 0.3878814243660646 1.0 0.6495656673116196 2 Q9Y3Z3 1 +GTPase effector domain [IPR020850] 0.7565824825362668 0.8591042208626387 0.3902830188367772 1.0 0.6495656673116196 3 Q05193,O00429 2 +Dynamin stalk domain [IPR000375] 0.7565824825362668 0.8591042208626387 0.3902830188367772 1.0 0.6495656673116196 3 Q05193,O00429 2 +Dynamin GTPase effector [IPR003130] 0.7565824825362668 0.8591042208626387 0.3902830188367772 1.0 0.6495656673116196 3 Q05193,O00429 2 +K Homology domain, type 1 [IPR004088] 0.4159346429971978 0.799611459803002 0.4239359457769875 1.0 0.6795342793734857 24 Q06787,P51114,P51116,Q9Y6M1 4 +Intermediate filament head, DNA-binding domain [IPR006821] 0.6019847783576815 0.7835424301203369 0.4333086475468581 1.0 0.6878687839869064 4 P08670 1 +Chromo shadow domain [IPR008251] 0.7348199892530853 0.7818166759513563 0.434322319273996 1.0 0.6880055105637726 3 P83916,Q13185 2 +ALIX V-shaped domain [IPR025304] 0.7408004297609463 0.7773990205808647 0.4369233901251683 1.0 0.6902831195427979 2 Q9H3S7 1 +Calcium uniporter protein, C-terminal [IPR006769] 0.7378458232608179 0.7664392554525533 0.4434149827559097 1.0 0.6946210421524732 2 Q9NWR8 1 +Alcohol dehydrogenase, N-terminal [IPR013154] 0.5354228558208769 0.7456738782905207 0.4558644424621889 1.0 0.7059236956082018 6 Q8N4Q0,Q8WWV3 2 +F-BAR domain [IPR031160] 0.7195056421278834 0.7284983311173754 0.4663085898937262 1.0 0.7161167630510795 3 Q9UKS6,Q96RU3 2 +FCH domain [IPR001060] 0.7195056421278834 0.7284983311173754 0.4663085898937262 1.0 0.7161167630510795 3 Q9UKS6,Q96RU3 2 +Protein OS9-like domain [IPR012913] 0.7257587966693577 0.7220792137243564 0.4702457771044828 1.0 0.7191851652932991 2 Q13438 1 +Reticulon [IPR003388] 0.716012896292311 0.716477610377774 0.473696487660064 1.0 0.7215480196195369 3 O95197,Q9NQC3 2 +K Homology domain [IPR004087] 0.4038281680124459 0.7144447071260613 0.4749522353612927 1.0 0.7215480196195369 24 Q06787,P51114,P51116,Q9Y6M1 4 +Sec23, C-terminal [IPR037550] 0.7233413913510618 0.7133035213373993 0.4756579589627923 1.0 0.722131278675587 2 Q15436 1 +SARAH domain [IPR011524] 0.7166263765780273 0.6891051586073745 0.4907570939600307 1.0 0.7325362209585069 2 Q13188 1 +Mst1 SARAH domain [IPR024205] 0.7166263765780273 0.6891051586073745 0.4907570939600307 1.0 0.7325362209585069 2 Q13188 1 +Cyclin-like [IPR013763] 0.7074046823621374 0.6870908019769695 0.492025510111568 1.0 0.7325362209585069 3 P14635 1 +Extracellular Endonuclease, subunit A [IPR020821] 0.7066093498119238 0.6843935068879754 0.4937267150504083 1.0 0.7325362209585069 3 P22413,O94919 2 +DNA/RNA non-specific endonuclease [IPR001604] 0.7066093498119238 0.6843935068879754 0.4937267150504083 1.0 0.7325362209585069 3 P22413,O94919 2 +FYVE zinc finger [IPR000306] 0.5158073896424604 0.6642025863844526 0.5065606583301738 1.0 0.7440423134978346 6 Q9NYA4,O14964 2 +Zinc finger, FYVE-related [IPR017455] 0.5158073896424604 0.6642025863844526 0.5065606583301738 1.0 0.7440423134978346 6 Q9NYA4,O14964 2 +Far upstream element-binding protein, C-terminal [IPR015096] 0.7088369594413104 0.6613792898059685 0.5083691040336231 1.0 0.7448592764202598 2 Q92945 1 +Zinc finger, TFIIB-type [IPR013137] 0.7053451517593334 0.6490762307314517 0.5162891045890199 1.0 0.7505229326802041 2 Q00403 1 +BRO1 domain [IPR004328] 0.6910263299301396 0.6321960261729059 0.5272587936613027 1.0 0.7506641583518998 3 Q9H3S7,Q8WUM4 2 +GAT domain [IPR004152] 0.6886919151222309 0.5915494690165872 0.5541523196753775 1.0 0.7717767080925662 2 Q6ZVM7 1 +Ribosomal protein L10e/L16 [IPR016180] 0.678485092667203 0.5573014966847618 0.5773214532871758 1.0 0.7872334874619422 2 Q9NX20 1 +Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141] 0.6782164920762799 0.5564112661192306 0.5779297389436691 1.0 0.7872899611780836 2 P20020 1 +RAVE complex protein Rav1 C-terminal [IPR022033] 0.6757990867579879 0.5484253838834969 0.5833998507727256 1.0 0.7903869211153776 2 Q9Y485 1 +Mu homology domain [IPR028565] 0.5339962375705477 0.5326562416847807 0.5942715621971666 1.0 0.8018207026098196 4 Q9BXS5,P48444,Q96CW1 3 +Phox homology [IPR001683] 0.4161182505937015 0.515885604366018 0.6059343089968561 1.0 0.8082547439431005 13 Q9H3E2,Q9Y2I1 2 +Stromalin conservative domain [IPR020839] 0.6655922643029781 0.5152416552018569 0.6063841640792809 1.0 0.8082547439431005 2 Q8WVM7 1 +STAG [IPR013721] 0.6655922643029781 0.5152416552018569 0.6063841640792809 1.0 0.8082547439431005 2 Q8WVM7 1 +PTBP1, RNA recognition motif 2-like [IPR021790] 0.5286213383499148 0.5140579133665141 0.6072115011143606 1.0 0.8082547439431005 4 Q8WVV9,Q9UKA9,P14866 3 +U2A'/phosphoprotein 32 family A, C-terminal [IPR003603] 0.5284002739267886 0.51329775886361 0.6077430514381561 1.0 0.8082547439431005 4 P39687 1 +Zinc finger, GRF-type [IPR010666] 0.6642492613483926 0.5109416265733676 0.6093919319854115 1.0 0.8082547439431005 2 Q13472 1 +DnaJ domain [IPR001623] 0.3822811097424614 0.5073797646395914 0.6118883811099785 1.0 0.8101172810144159 21 Q9NZJ4,Q9NVH1,Q99543,Q9UDY4,Q96KC8,Q8IXB1 6 +DOCKER domain [IPR027357] 0.6392712764531 0.4694183941861012 0.6387706029922637 1.0 0.8226098175147762 3 Q14185 1 +C2 DOCK-type domain [IPR027007] 0.6392712764531 0.4694183941861012 0.6387706029922637 1.0 0.8226098175147762 3 Q14185 1 +SET domain [IPR001214] 0.4189435206977188 0.4682262523025461 0.6396228004740778 1.0 0.8226098175147762 11 Q96KQ7 1 +Ras-associating (RA) domain [IPR000159] 0.5059606457177602 0.4382525526909168 0.6612032166072119 1.0 0.8348970780820649 4 Q96L92 1 +MYST, zinc finger domain [IPR040706] 0.6325543916196557 0.4143319404916768 0.6786310251262506 1.0 0.8407090820666329 2 O95251 1 +Histone acetyltransferase domain, MYST-type [IPR002717] 0.6325543916196557 0.4143319404916768 0.6786310251262506 1.0 0.8407090820666329 2 O95251 1 +Isopropylmalate dehydrogenase-like domain [IPR024084] 0.4590189225130934 0.3960639171520987 0.6920578762548311 1.0 0.846387353193769 5 P48735 1 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.4576451011578594 0.3914050655672591 0.6954978486100787 1.0 0.8485779685537437 5 Q32P28 1 +Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481] 0.6226161697555677 0.3861169601333463 0.6994100496303934 1.0 0.8500657061526792 2 Q9UID3 1 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.4087474012851558 0.34361855995522 0.7311331649165425 1.0 0.8607469188019389 8 Q32P28 1 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.4087474012851558 0.34361855995522 0.7311331649165425 1.0 0.8607469188019389 8 Q32P28 1 +LEM domain [IPR003887] 0.4187386202958775 0.2972823092147841 0.7662509866629734 1.0 0.8754203609661311 6 Q86XL3 1 +Gelsolin-like domain [IPR007123] 0.4170475934390929 0.2916796774881581 0.7705315488954279 1.0 0.8782816387140739 6 Q15436,Q15437,Q13045,P53992,O95486 5 +Dedicator of cytokinesis C, C2 domain [IPR037808] 0.5852806876175033 0.2900882673997162 0.7717487113335781 1.0 0.8789936378221598 2 Q96HP0 1 +Dedicator of cytokinesis C/D, N-terminal [IPR021816] 0.5852806876175033 0.2900882673997162 0.7717487113335781 1.0 0.8789936378221598 2 Q96HP0 1 +Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422] 0.5815202793446103 0.2813425260466373 0.7784476958885285 1.0 0.879868309981434 2 O75146 1 +GINS subunit, domain A [IPR021151] 0.5734622616169728 0.2631986278031016 0.7923974883839351 1.0 0.8905261543869815 2 Q9BRT9 1 +Sec23/Sec24, trunk domain [IPR006896] 0.4169354838709632 0.2629244404651678 0.7926088180995154 1.0 0.8905261543869815 5 Q15436,P53992,O95486,Q15437 4 +Zinc finger, Sec23/Sec24-type [IPR006895] 0.4169354838709632 0.2629244404651678 0.7926088180995154 1.0 0.8905261543869815 5 Q15436,P53992,O95486,Q15437 4 +Sec23/Sec24 beta-sandwich [IPR012990] 0.4169354838709632 0.2629244404651678 0.7926088180995154 1.0 0.8905261543869815 5 Q15436,P53992,O95486,Q15437 4 +Sec23/Sec24, helical domain [IPR006900] 0.4169354838709632 0.2629244404651678 0.7926088180995154 1.0 0.8905261543869815 5 Q15436,P53992,O95486,Q15437 4 +Vps4 oligomerisation, C-terminal [IPR015415] 0.4410104810534841 0.2500396299512268 0.8025567015087591 1.0 0.8976347441543171 4 O75449,O75351,Q9UN37 3 +ELMO domain [IPR006816] 0.5662100456620947 0.2475740805600588 0.8044639672046325 1.0 0.8983346869562235 2 Q96JJ3 1 +Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468] 0.4364418167159484 0.2387252931251744 0.8113186026394346 1.0 0.9032262441221274 4 Q8NEN9,A0FGR8,Q8IWB9 3 +ABC transporter-like, ATP-binding domain [IPR003439] 0.3560563368061407 0.2361390969098127 0.813324736694278 1.0 0.9043502671493376 14 P08183,Q03519,P33527,O14678 4 +Survival motor neuron [IPR010304] 0.5605694332527488 0.235888751948048 0.8135189966368663 1.0 0.9043502671493376 2 O75940 1 +Elongation factor 1 beta central acidic region, eukaryote [IPR018940] 0.556809024979853 0.228327232509213 0.8193918551623964 1.0 0.9080161558545964 2 P29692 1 +Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038] 0.556809024979853 0.228327232509213 0.8193918551623964 1.0 0.9080161558545964 2 P29692 1 +Tim44-like domain [IPR007379] 0.551705613752341 0.2183591886754339 0.827149260995331 1.0 0.9106314869659172 2 O43615 1 +Potassium channel tetramerisation-type BTB domain [IPR003131] 0.5506312113886533 0.2163038993711014 0.8287508697541912 1.0 0.912056316973548 2 Q96CX2 1 +Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861] 0.5314347125201415 0.2047099708791874 0.8377987297491756 1.0 0.9175748081382936 3 Q02809,O00469 2 +Rho GTPase-activating protein domain [IPR000198] 0.3750148201826331 0.2038580285597472 0.8384644446263043 1.0 0.9176407256386 7 O00459 1 +RNA recognition motif domain, eukaryote [IPR003954] 0.3481964541142734 0.1985350730318923 0.8426264465408748 1.0 0.9201592443455192 14 Q14011,Q01085,P31483,P38159 4 +Lon, substrate-binding domain [IPR003111] 0.5401557883427216 0.1970549451724033 0.8437845406012432 1.0 0.9207461316527724 2 P36776 1 +Peptidase S16, Lon proteolytic domain [IPR008269] 0.5401557883427216 0.1970549451724033 0.8437845406012432 1.0 0.9207461316527724 2 P36776 1 +Rab-GTPase-TBC domain [IPR000195] 0.3897849462365527 0.1891213035616661 0.8499977449458789 1.0 0.9256377219976636 5 O60343,Q66K14,Q9Y3P9,Q8TC07 4 +Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 0.3592392964573513 0.1865261211935815 0.8520321965366933 1.0 0.9267669290508638 10 Q8TCG2 1 +Sorting nexin, N-terminal [IPR005329] 0.5326349717969374 0.1841192111079033 0.8539199358294454 1.0 0.9277116256338208 2 O60749 1 +Translation initiation factor IF- 2, domain 3 [IPR023115] 0.5310233682513993 0.1814432040179253 0.856019709715784 1.0 0.9279541391036652 2 P46199 1 +Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798] 0.5283373623421814 0.1770582341001018 0.8594626478903526 1.0 0.9310060884595386 2 Q9UKA9 1 +Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164] 0.5280687617512749 0.1766248892760859 0.8598030426296801 1.0 0.931034900540971 2 Q5JTZ9 1 +Serpin domain [IPR023796] 0.5118216012896196 0.170145617457151 0.8648956189617467 1.0 0.9355250825590604 3 P50454,P30740 2 +Histidine kinase domain [IPR005467] 0.5099408919935428 0.1670685346563512 0.8673161237208702 1.0 0.9364362951527736 3 Q15120,O14874 2 +Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955] 0.5099408919935428 0.1670685346563512 0.8673161237208702 1.0 0.9364362951527736 3 Q15120,O14874 2 +Band 4.1 domain [IPR019749] 0.3425680170246101 0.1585946210448066 0.8739882669429804 1.0 0.941926330555693 13 P23458 1 +FERM central domain [IPR019748] 0.3425680170246101 0.1585946210448066 0.8739882669429804 1.0 0.941926330555693 13 P23458 1 +FERM domain [IPR000299] 0.3430591302289504 0.1508351265491304 0.8801057762783575 1.0 0.9461137094992343 12 P23458 1 +Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585] 0.5089981197958615 0.1482291041711955 0.8821619637161828 1.0 0.9466092391847792 2 Q13243 1 +Histone deacetylase domain [IPR023801] 0.5073865162503334 0.1460412512113769 0.8838888237521298 1.0 0.9466294253691568 2 Q13547 1 +Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.4940891993551753 0.1427807333467066 0.8864633537265438 1.0 0.9481387060225868 3 Q1KMD3,Q9BUJ2 2 +PABP, RNA recognition motif 2 [IPR045305] 0.4966424926134737 0.1322790181263314 0.8947636026390644 1.0 0.95392152678049 2 Q13310 1 +Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253] 0.4891216760676804 0.1234806771447236 0.901726474589791 1.0 0.9606543806491598 2 O75351 1 +SH3 domain [IPR001452] 0.3119120465050368 0.1201302971779183 0.9043799324983954 1.0 0.9620994118762062 42 Q5T2T1,P46108,P07947,Q14168,Q14247,P62993,Q9NZW5,Q6XZF7,O14936,O00459,Q96PC5,Q14185,Q9UKS6,Q00013,Q14847,Q9UQB8,Q12959,Q96RU3,Q92783 19 +ISWI, HAND domain [IPR015194] 0.4848240666129484 0.1187538584140525 0.9054703655608474 1.0 0.962569177577583 2 P28370 1 +SLIDE domain [IPR015195] 0.4848240666129484 0.1187538584140525 0.9054703655608474 1.0 0.962569177577583 2 P28370 1 +Asparagine synthase [IPR001962] 0.4837496642492523 0.1176057582766634 0.9063800421687476 1.0 0.962980484684474 2 Q9NWL6 1 +Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036] 0.4832124630674049 0.1170367070222447 0.9068309653550456 1.0 0.962980484684474 2 Q96C36 1 +Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939] 0.4832124630674049 0.1170367070222447 0.9068309653550456 1.0 0.962980484684474 2 Q96C36 1 +Exosome complex component, N-terminal domain [IPR025721] 0.4807950577491298 0.1145169738517694 0.9088279917250416 1.0 0.9644108195451354 2 Q9Y3B2 1 +SCP2 sterol-binding domain [IPR003033] 0.4717893605588301 0.1135299236595602 0.9096104407882062 1.0 0.9648960235318584 3 Q6YN16,P51659 2 +NOPS [IPR012975] 0.4658785599140144 0.1067148435967984 0.9150152063672228 1.0 0.9699357332231332 3 Q8WXF1,P23246 2 +RNA recognition motif domain [IPR000504] 0.3527898690600058 0.1058018117558128 0.91573959928698 1.0 0.9703569253873108 121 P23588,P52597,P62995,Q9BWF3,Q92879,Q13595,O14979,Q9UHX1,Q9UKA9,P22626,P07910,P52756,Q9Y6M1,Q14011,P31943,Q8WUA2,Q14103,O75494,Q01085,Q96E39,Q8IUH3,P43243,P55795,P98179,Q99729,P31483,Q9GZT3,P38159,P31942,O60506,Q13242,Q15056,O43390,P35637,Q13151,P51991,Q92804,Q01844,Q16629,Q07955,Q8IXT5,P98175 42 +Phosphatidylinositol-specific phospholipase C, X domain [IPR000909] 0.4582326081117376 0.0941025166633922 0.9250277212466356 1.0 0.9763186850517732 2 P16885 1 +Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711] 0.4582326081117376 0.0941025166633922 0.9250277212466356 1.0 0.9763186850517732 2 P16885 1 +PLC-gamma, N-terminal SH2 domain [IPR035024] 0.4582326081117376 0.0941025166633922 0.9250277212466356 1.0 0.9763186850517732 2 P16885 1 +PLC-gamma, C-terminal SH2 domain [IPR035023] 0.4582326081117376 0.0941025166633922 0.9250277212466356 1.0 0.9763186850517732 2 P16885 1 +DFDF domain [IPR025762] 0.4515175933387064 0.0890469072089108 0.929044631595828 1.0 0.9788620106338144 2 Q9BX40 1 +FDF domain [IPR019050] 0.4515175933387064 0.0890469072089108 0.929044631595828 1.0 0.9788620106338144 2 Q9BX40 1 +Lsm14-like, N-terminal [IPR025609] 0.4515175933387064 0.0890469072089108 0.929044631595828 1.0 0.9788620106338144 2 Q9BX40 1 +HDGF-related, PWWP domain [IPR035496] 0.4451907576571636 0.0858122959426336 0.9316156317876 1.0 0.9795380208699672 3 Q7Z4V5,P51858 2 +Major sperm protein (MSP) domain [IPR000535] 0.4449220849005816 0.0855699933057838 0.9318082528148466 1.0 0.9795380208699672 3 Q8NHP6,Q9P0L0 2 +Lens epithelium-derived growth factor, integrase-binding domain [IPR021567] 0.4450711791565963 0.0846009253048734 0.9325786634203536 1.0 0.9795380208699672 2 Q7Z4V5 1 +CELF1/2, RNA recognition motif 3 [IPR034199] 0.4445339779747467 0.084247850213531 0.9328593744177962 1.0 0.9795380208699672 2 Q92879 1 +CELF1/2, RNA recognition motif 2 [IPR034198] 0.4445339779747467 0.084247850213531 0.9328593744177962 1.0 0.9795380208699672 2 Q92879 1 +CELF1/2, RNA recognition motif 1 [IPR034196] 0.4445339779747467 0.084247850213531 0.9328593744177962 1.0 0.9795380208699672 2 Q92879 1 +LEM-like domain [IPR013146] 0.4423851732473766 0.0828617367506128 0.933961479020596 1.0 0.9795380208699672 2 P42166 1 +Methyltransferase domain [IPR025714] 0.4383561643835633 0.0803737168493582 0.9359400301781068 1.0 0.9795380208699672 2 Q8NEC7 1 +Extended synaptotagmin, C-terminal C2 domain [IPR037752] 0.4362073596561882 0.0791046169019795 0.9369494112669252 1.0 0.9795380208699672 2 A0FGR8 1 +Extended synaptotagmin, C2A domain [IPR037733] 0.4362073596561882 0.0791046169019795 0.9369494112669252 1.0 0.9795380208699672 2 A0FGR8 1 +Extended synaptotagmin, C2B domain [IPR037749] 0.4362073596561882 0.0791046169019795 0.9369494112669252 1.0 0.9795380208699672 2 A0FGR8 1 +Synaptotagmin, SMP domain [IPR039010] 0.4362073596561882 0.0791046169019795 0.9369494112669252 1.0 0.9795380208699672 2 A0FGR8 1 +F-box domain [IPR001810] 0.3356602482098735 0.0755692432672763 0.9397618067882972 1.0 0.9815685932732698 5 Q6PIJ6 1 +Zinc finger, CCHC-type [IPR001878] 0.3301276956852618 0.0754154286850028 0.9398841838521604 1.0 0.9815685932732698 8 Q9NUD5,Q9BWF3 2 +Ribosomal protein/NADH dehydrogenase domain [IPR007741] 0.4177861364857497 0.0646581178487519 0.948446210120832 1.0 0.9870139667996288 3 P82663,Q8N983 2 +Zinc finger, MYM-type [IPR010507] 0.4047810905183952 0.064655408691964 0.9484483672016552 1.0 0.9870139667996288 2 Q9UBW7 1 +Ribosomal L28e/Mak16 [IPR029004] 0.4012892828364246 0.0634692506726276 0.9493928442684209 1.0 0.9870139667996288 2 Q9BXY0 1 +Myb domain [IPR017930] 0.3250093621514209 0.0615601737442765 0.9509130935054162 1.0 0.9870139667996288 8 Q99543 1 +EF hand associated, type-1 [IPR013566] 0.394574268063392 0.0613890038530319 0.9510494094976488 1.0 0.9870139667996288 2 Q8IXI2 1 +EF hand associated, type-2 [IPR013567] 0.394574268063392 0.0613890038530319 0.9510494094976488 1.0 0.9870139667996288 2 Q8IXI2 1 +MIRO domain [IPR020860] 0.394574268063392 0.0613890038530319 0.9510494094976488 1.0 0.9870139667996288 2 Q8IXI2 1 +HECT domain [IPR000569] 0.3201051925099364 0.0613427325442857 0.9510862592113714 1.0 0.9870139667996288 12 Q96J02,P46934,Q05086 3 +Sirtuin family, catalytic core domain [IPR026590] 0.3679828095621854 0.0553684348569279 0.9558449425821962 1.0 0.987407381525636 2 Q8IXJ6 1 +Legume-like lectin [IPR005052] 0.362073596561917 0.0544288501840356 0.9565934937937908 1.0 0.987407381525636 2 Q12907 1 +Septin-type guanine nucleotide-binding (G) domain [IPR030379] 0.3997850617947254 0.0543280602535536 0.956673793711276 1.0 0.987407381525636 3 Q15019,Q9UHD8 2 +ABC-transporter extension domain [IPR032781] 0.3607305936073033 0.0542321379921421 0.956750215937181 1.0 0.987407381525636 2 Q9NUQ8 1 +Zinc finger, UBP-type [IPR001607] 0.3204301075268745 0.0520998292956599 0.9584491489853928 1.0 0.987407381525636 5 Q7Z569,Q9UPT9,Q53GS9,Q8TEY7 4 +Translation initiation factor IF2/IF5 domain [IPR002735] 0.3421971528337348 0.052067236340335 0.9584751191527734 1.0 0.987407381525636 2 P55010 1 +bMERB domain [IPR022735] 0.3352135374697879 0.0514772047444819 0.9589452657425596 1.0 0.987407381525636 2 Q8N3F8 1 +NudC N-terminal domain [IPR025934] 0.3322589309696452 0.0512583274923306 0.9591196742692564 1.0 0.987407381525636 2 Q8IVD9 1 +CAP Gly-rich domain [IPR000938] 0.3113917248790862 0.0314808360223109 0.9748860752085118 1.0 0.9984629848244776 3 Q14203,Q99426 2 +DNA mismatch repair protein MutS, connector domain [IPR007860] 0.3036002149381971 0.0308395320380509 0.975397513395033 1.0 0.9984629848244776 3 P20585,P52701 2 +DNA mismatch repair protein MutS-like, N-terminal [IPR007695] 0.3036002149381971 0.0308395320380509 0.975397513395033 1.0 0.9984629848244776 3 P20585,P52701 2 +DNA mismatch repair protein MutS, C-terminal [IPR000432] 0.3036002149381971 0.0308395320380509 0.975397513395033 1.0 0.9984629848244776 3 P20585,P52701 2 +DNA mismatch repair protein MutS, core [IPR007696] 0.3036002149381971 0.0308395320380509 0.975397513395033 1.0 0.9984629848244776 3 P20585,P52701 2 +Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.3006448146157836 0.0306281094837772 0.9755661245354504 1.0 0.9984629848244776 3 O60884,P31689 2 +TGS [IPR004095] 0.3112076230429733 0.030540791637716 0.975635761519548 1.0 0.9984629848244776 7 Q9NTK5 1 +FAD-binding domain, ferredoxin reductase-type [IPR017927] 0.2931219774314795 0.0301597396425912 0.9759396570243032 1.0 0.9984629848244776 3 Q9UHQ9,P16435 2 +Oxidoreductase FAD/NAD(P)-binding [IPR001433] 0.2931219774314795 0.0301597396425912 0.9759396570243032 1.0 0.9984629848244776 3 Q9UHQ9,P16435 2 +Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709] 0.2931219774314795 0.0301597396425912 0.9759396570243032 1.0 0.9984629848244776 3 Q9UHQ9,P16435 2 +RNA-binding S4 domain [IPR002942] 0.2743148844707045 0.029345540586673 0.9765890063905068 1.0 0.9984629848244776 3 Q9NV31,P46781 2 +Zinc finger, LIM-type [IPR001781] 0.3081896551724071 0.0205319518331201 0.983619023567551 1.0 1.0 13 Q9UGI8,Q96HC4,Q9NR12,Q16527,Q14847,Q7RTP6,Q8WWI1,Q13642,P49023,Q15942,Q9UHB6,Q8N3F8 12 +SANT domain [IPR017884] 0.3069750883262792 0.0119337537393321 0.9904784681401652 1.0 1.0 10 Q99543 1 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..10dafa6c52cd30e4fbfc67329f1619aedaf9b655 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, SH3 domain [IPR035723]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "16S/18S rRNA aminocarboxypropyltransferase Tsr3, C-terminal [IPR007177]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3'5'-cyclic nucleotide phosphodiesterase, catalytic domain [IPR002073]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-3' exoribonuclease 1, SH3-like domain [IPR041385]", "5'-AMP-activated protein kinase alpha 1 catalytic subunit, C-terminal [IPR039137]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA C-terminal domain [IPR032423]", "AAA lid domain [IPR041083]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADD domain [IPR025766]", "ADNP, zinc finger domain [IPR045762]", "AF4/FMR2, C-terminal homology domain [IPR043640]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARF GTPase-activating protein GIT1, C-terminal [IPR022018]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARIP4, DEXH-box helicase domain [IPR044573]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ASCH domain [IPR007374]", "ATM, catalytic domain [IPR044107]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "ATRX, ADD domain [IPR041430]", "AWS domain [IPR006560]", "Abl Interactor 1, SH3 domain [IPR035725]", "Abl-interactor, homeo-domain homologous domain [IPR012849]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acid ceramidase, N-terminal [IPR029130]", "Acid sphingomyelinase/endopolyphosphatase, metallophosphatase domain [IPR041805]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adenomatous polyposis coli protein basic domain [IPR009234]", "Adenomatous polyposis coli, N-terminal dimerisation domain [IPR032038]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase, N-terminal [IPR032628]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Adenylyl cyclase class-3/4/guanylyl cyclase [IPR001054]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanine racemase, N-terminal [IPR001608]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin [IPR001599]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-2-macroglobulin, TED domain [IPR041813]", "Alpha-2-macroglobulin, bait region domain [IPR011625]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-amylase/branching enzyme, C-terminal all beta [IPR006048]", "Alpha-dystroglycan N-terminal domain 2 [IPR041631]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha-macroglobulin, receptor-binding [IPR009048]", "Alpha-macroglobulin-like, TED domain [IPR011626]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Alpha/beta hydrolase fold-3 [IPR013094]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, amyloid-beta peptide [IPR013803]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4 long domain [IPR024790]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 1 [IPR041880]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 2 [IPR041882]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arf GTPase-activating protein GIT1/2, coiled-coil domain [IPR032352]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Attractin-like, C-type lectin-like domain [IPR034011]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "Autophagy protein ATG17-like domain [IPR045326]", "Autophagy-related protein 11, C-terminal [IPR019460]", "Autophagy-related, C-terminal [IPR015412]", "B(0)AT2, solute-binding domain [IPR042934]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BARD1, Zinc finger, RING-type [IPR039503]", "BAT2, N-terminal [IPR009738]", "BAZ2A/BAZ2B, bromodomain [IPR037374]", "BCAS3 domain [IPR022175]", "BCL-6 corepressor, PCGF1 binding domain [IPR032365]", "BCL-6 corepressor, non-ankyrin-repeat domain [IPR031628]", "BCL10, CARD domain [IPR042143]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BEN domain [IPR018379]", "BET1, SNARE domain [IPR039899]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BR140-related, PWWD domain [IPR035502]", "BRAP2, RNA recognition motif [IPR034932]", "BRCA1, serine-rich domain [IPR025994]", "BRCA1-associated 2 [IPR011422]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BRPF2, PHD domain [IPR042009]", "BRPF2, ePHD domain [IPR042004]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Bcr-Abl oncoprotein oligomerisation [IPR015123]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-lactamase-related [IPR001466]", "Beta-mannosidase, Ig-fold domain [IPR041625]", "Beta-trefoil DNA-binding domain [IPR015350]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Bud22 domain [IPR015158]", "Butyrophilin subfamily 1/2, SPRY/PRY domain [IPR037958]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CALCOCO1/2, zinc finger UBZ1-type [IPR041641]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARD domain [IPR001315]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCD97-like, C-terminal [IPR040233]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CCZ1/INTU, second Longin domain [IPR043988]", "CCZ1/INTU/HPS4, third Longin domain [IPR043989]", "CCZ1/INTU/HSP4, first Longin domain [IPR043987]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CKK domain [IPR014797]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COMM domain [IPR017920]", "COMPASS complex Set1 subunit, N-SET domain [IPR024657]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CUB domain [IPR000859]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, N-terminal [IPR013164]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-binding protein cabin-1, MEF2-binding domain [IPR015134]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium binding and coiled-coil domain-like [IPR012852]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calmodulin-regulated spectrin-associated protein, CH domain [IPR022613]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Calsyntenin, C-terminal [IPR045588]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carboxypeptidase E, carboxypeptidase domain [IPR034232]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cathepsin propeptide inhibitor domain (I29) [IPR013201]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cation/H+ exchanger [IPR006153]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Caudal-like activation domain [IPR006820]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cdc6, C-terminal [IPR015163]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein Cenp-F, N-terminal [IPR018463]", "Centromere protein Cenp-F, leucine-rich repeat-containing domain [IPR019513]", "Centrosomal CEP44 domain [IPR029157]", "Centrosomal protein of 290kDa, coiled-coil region [IPR032321]", "Centrosomin, N-terminal motif 1 [IPR012943]", "Chaperone DnaJ, C-terminal [IPR002939]", "Checkpoint kinase 1, catalytic domain [IPR034670]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron Rho-interacting kinase, catalytic domain [IPR037708]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain [IPR041715]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class V myosin, motor domain [IPR036103]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Classical Protein Kinase C alpha, catalytic domain [IPR034663]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coagulation factor 5/8 C-terminal domain [IPR000421]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Collectrin domain [IPR031588]", "Complement Clr-like EGF domain [IPR026823]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Conserved oligomeric Golgi complex, subunit 4 [IPR013167]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Copper type II ascorbate-dependent monooxygenase, C-terminal [IPR024548]", "Copper type II, ascorbate-dependent monooxygenase, N-terminal [IPR000323]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DEP domain [IPR000591]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DG-type SEA domain [IPR030398]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIX domain [IPR001158]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mismatch repair protein family, N-terminal [IPR002099]", "DNA mismatch repair protein, S5 domain 2-like [IPR013507]", "DNA mitochondrial polymerase, exonuclease domain [IPR041336]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor Dna2, N-terminal [IPR014808]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase 3-like, TOPRIM domain [IPR034144]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IA, DNA-binding domain [IPR003602]", "DNA topoisomerase, type IA, central [IPR013497]", "DNA topoisomerase, type IA, domain 2 [IPR003601]", "DNA topoisomerase, type IA, zn finger [IPR013498]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-binding protein SMUBP-2, R3H domain [IPR034072]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family A, palm domain [IPR001098]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase III subunit RPC5, C-terminal [IPR045576]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding domain, Est1-type [IPR018834]", "DNA/RNA-binding protein Alba-like [IPR002775]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DTX3L, RING-HC finger [IPR042843]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Death effector domain [IPR001875]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dedicator of cytokinesis, N-terminal domain [IPR032376]", "Dehydrogenase, E1 component [IPR001017]", "Deltex, C-terminal [IPR039396]", "Deoxycytidylate deaminase domain [IPR035105]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "DhaK domain [IPR004006]", "DhaL domain [IPR004007]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dienelactone hydrolase [IPR002925]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Dishevelled C-terminal [IPR024580]", "Dishevelled protein domain [IPR003351]", "Disks large homologue 1, N-terminal PEST domain [IPR019590]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homolog subfamily C member 16, TRX domain [IPR043361]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DM14 [IPR006608]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4171 [IPR025228]", "Domain of unknown function DUF4195 [IPR025243]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4211 [IPR025451]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4477 [IPR027951]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF4757 [IPR031865]", "Domain of unknown function DUF4976 [IPR032506]", "Domain of unknown function DUF5050 [IPR032485]", "Domain of unknown function DUF5595 [IPR040967]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Domain of unknown function DUF775 [IPR008493]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-binding protein, first C-terminal SH3 domain [IPR035820]", "Dynamin-binding protein, first N-terminal SH3 domain [IPR035817]", "Dynamin-binding protein, second N-terminal SH3 domain [IPR035818]", "Dynamin-binding protein, third N-terminal SH3 domain [IPR035819]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "Dystroglycan, C-terminal [IPR008465]", "Dystroglycan-type cadherin-like [IPR006644]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase RNF149, RING finger, H2 subclass [IPR042712]", "E3 ubiquitin-protein ligase RNF31, PUB domain [IPR040641]", "E3 ubiquitin-protein ligase RNF31, UBA-like domain [IPR032065]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB-1 binding [IPR009232]", "EB1, C-terminal [IPR004953]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF domain [IPR024731]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELK domain [IPR005539]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERCC4 domain [IPR006166]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXOG, C-terminal [IPR041003]", "EXPERA domain [IPR033118]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin B2, SH3 domain [IPR035640]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enhancer of polycomb-like, N-terminal [IPR019542]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin type-A receptor 2, ligand binding domain [IPR034263]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst complex component Sec3, C-terminal [IPR019160]", "Exocyst complex component Sec3, PIP2-binding N-terminal domain [IPR028258]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease Xrn1, D2/D3 domain [IPR041106]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exostosin, GT47 domain [IPR040911]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain [IPR002938]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM192A/Fyv6, N-terminal [IPR019331]", "FAM3C (ILEI) domain [IPR039475]", "FAM69, protein-kinase domain [IPR022049]", "FAM83, N-terminal [IPR012461]", "FAM91, C-terminal domain [IPR028097]", "FAM91, N-terminal domain [IPR028091]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM F1 lobe ubiquitin-like domain [IPR041155]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FLYWCH-type zinc finger-containing protein, N-terminal [IPR029279]", "FMP27, C-terminal [IPR019443]", "FMP27, GFWDK domain [IPR019441]", "FMP27, N-terminal [IPR019439]", "FRAS1-related extracellular matrix protein, N-terminal domain [IPR045658]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Fanconi anaemia group A protein, N-terminal domain [IPR031729]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "FeS cluster biogenesis [IPR000361]", "Ferritin-like diiron domain [IPR009040]", "Ferritin/DPS protein domain [IPR008331]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Ferrodoxin-fold anticodon-binding domain [IPR005121]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein [IPR003382]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Focadhesin/RST, DUF3730 [IPR022542]", "Follistatin-like, N-terminal [IPR003645]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formin-binding protein 1, F-BAR domain [IPR037449]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Freud, C2 domain [IPR037772]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Furin-like cysteine-rich domain [IPR006211]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein, beta subunit [IPR001632]", "G2 and S phase-expressed protein 1, N-terminal [IPR032768]", "G2 nidogen/fibulin G2F [IPR006605]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GH15-like domain [IPR011613]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GIT, Spa2 homology (SHD) domain [IPR013724]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPCR, family 2-like [IPR017981]", "GPI ethanolamine phosphate transferase 2, C-terminal [IPR045687]", "GPI ethanolamine phosphate transferase 2, N-terminal [IPR037674]", "GPI ethanolamine phosphate transferase 3, N-terminal [IPR037675]", "GPR domain [IPR000965]", "GPS motif [IPR000203]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galactosyltransferase, C-terminal [IPR027791]", "Galactosyltransferase, N-terminal [IPR027995]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-butyrobetaine hydroxylase-like, N-terminal [IPR010376]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gelsolin-like domain [IPR007123]", "Germinal-centre associated nuclear protein, CID domain [IPR031910]", "Germinal-centre associated nuclear protein, MCM3AP domain [IPR031907]", "Germinal-centre associated nuclear protein, nucleoporin homology domain [IPR031908]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 13, N-terminal [IPR004193]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase 64 domain [IPR015338]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Groucho/TLE, N-terminal Q-rich domain [IPR005617]", "Growth factor receptor domain 4 [IPR032778]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase, subfamily IIID [IPR011943]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HEPN domain [IPR007842]", "HERC2, APC10 domain [IPR037976]", "HERC2, zinc finger, ZZ-type [IPR041987]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HOOK, N-terminal [IPR043936]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Heavy metal-associated domain, HMA [IPR006121]", "Heavy metal-associated domain, copper ion-binding [IPR006122]", "Helical and beta-bridge domain [IPR010643]", "Helicase Helix-turn-helix domain [IPR029491]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histidyl-anticodon-binding [IPR033656]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase complex subunit SAP30 zinc-finger [IPR025717]", "Histone deacetylase complex subunit SAP30, Sin3 binding domain [IPR025718]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homeobox domain, metazoa [IPR020479]", "Homocysteine-binding domain [IPR003726]", "Hook, C-terminal [IPR008636]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "ITPR-interacting domain [IPR029325]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Impact, N-terminal [IPR001498]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol 1,3,4-trisphosphate 5/6-kinase, ATP-grasp domain [IPR040464]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Inositol-tetrakisphosphate 1-kinase, N-terminal [IPR041429]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrator complex subunit 5, C-terminal [IPR029444]", "Integrator complex subunit 5, N-terminal [IPR029445]", "Integrin alpha-2 [IPR013649]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon gamma receptor, poxvirus/mammal [IPR021126]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intersectin-2, fifth SH3 domain [IPR035741]", "Intersectin-2, first SH3 domain [IPR035737]", "Intersectin-2, fourth SH3 domain [IPR035740]", "Intersectin-2, second SH3 domain [IPR035738]", "Intersectin-2, third SH3 domain [IPR035739]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JAK, FERM F2 lobe domain [IPR041046]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "Jak1, pleckstrin homology-like domain [IPR041381]", "JmjC domain [IPR003347]", "JmjN domain [IPR003349]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KAP family P-loop domain [IPR011646]", "KASH domain [IPR012315]", "KELK-motif containing domain [IPR031597]", "KHDRBS, Qua1 domain [IPR032571]", "KIND domain [IPR011019]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kin17, KOW domain [IPR041995]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Cenp-F/LEK1, Rb protein-binding domain [IPR018302]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L1 transposable element, RRM domain [IPR043636]", "L1 transposable element, dsRBD-like domain [IPR035300]", "L1 transposable element, trimerization domain [IPR035301]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "L27-1 [IPR015143]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LCCL domain [IPR004043]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIM interaction domain [IPR041363]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV [IPR000034]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Liprin-alpha, SAM domain repeat 1 [IPR037620]", "Liprin-alpha, SAM domain repeat 2 [IPR037621]", "Liprin-alpha, SAM domain repeat 3 [IPR037622]", "Listerin, zinc finger, RING-type [IPR039804]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "LysM domain [IPR018392]", "Lysine-specific demethylase-like domain [IPR013637]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MAGE homology domain [IPR002190]", "MAM domain [IPR000998]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MCM3AP, RNA recognition motif [IPR034265]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MGA, conserved domain [IPR032060]", "MGRN1/RNF157, modified RING finger, C3HC5-type [IPR045195]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MMS22-like, C-terminal [IPR029424]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MTMR14, PH-GRAM domain [IPR039803]", "MTMR4, PH-GRAM domain [IPR035997]", "MTMR6, PH-GRAM domain [IPR035998]", "MYST, zinc finger domain [IPR040706]", "Mab-21 domain [IPR024810]", "Macro domain [IPR002589]", "Macroglobulin domain MG3 [IPR041555]", "Macroglobulin domain [IPR002890]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "Mannosidase Ig/CBM-like domain [IPR041447]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Mediator complex, subunit Med12 [IPR019035]", "Mediator complex, subunit Med12, LCEWAV-domain [IPR021990]", "Mediator complex, subunit Med12, catenin-binding [IPR021989]", "Mediator complex, subunit Med25, NR box [IPR021406]", "Mediator complex, subunit Med25, PTOV domain [IPR021394]", "Mediator complex, subunit Med25, synapsin 1 [IPR021397]", "Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain [IPR021419]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mff-like domain [IPR039433]", "MgsA AAA+ ATPase C-terminal [IPR021886]", "Mib-herc2 [IPR010606]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondria fission protein Fis1, cytosolic domain [IPR033745]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "Mitogen-activated protein kinase kinase kinase, N-terminal [IPR045801]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdenum cofactor synthesis C-terminal [IPR010505]", "Molybdopterin cofactor biosynthesis C (MoaC) domain [IPR002820]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mot1, ATP-binding domain [IPR044078]", "Mot1, central domain [IPR022707]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Mvd1, C-terminal [IPR041431]", "Myb domain [IPR017930]", "Myc-type, basic helix-loop-helix (bHLH) domain [IPR011598]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin 5a, cargo-binding domain [IPR037988]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotonic dystrophy protein kinase, coiled coil [IPR014930]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-CoR, GPS2-interacting domain [IPR031557]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "NACHT nucleoside triphosphatase [IPR007111]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NFRKB winged helix-like domain [IPR025220]", "NFkappaB IPT domain [IPR033926]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIDO domain [IPR003886]", "NIF system FeS cluster assembly, NifU, C-terminal [IPR001075]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Na-Ca exchanger/integrin-beta4 [IPR003644]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neogenin, C-terminal [IPR010560]", "Neurexin/syndecan/glycophorin C [IPR003585]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Neuropilin, C-terminal [IPR022579]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Notch domain [IPR000800]", "Notch, C-terminal [IPR024600]", "Notch, NOD domain [IPR010660]", "Notch, NODP domain [IPR011656]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear coactivator [IPR022174]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear hormone receptor, ligand-binding domain [IPR000536]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nucleolar 27S pre-rRNA processing, Urb2/Npa2, C-terminal [IPR018849]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NudC domain-containing protein 3, p23 domain [IPR037905]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OST-HTH/LOTUS domain [IPR025605]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, C-terminal [IPR032630]", "P-type ATPase, N-terminal [IPR032631]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAN2 domain [IPR028881]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAS domain [IPR000014]", "PAS fold [IPR013767]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PCNA-associated factor, histone-like domain [IPR031444]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PDZ-associated domain of NMDA receptors [IPR019583]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K p85 subunit, C-terminal SH2 domain [IPR035020]", "PI3K p85 subunit, N-terminal SH2 domain [IPR035022]", "PI3K regulatory subunit p85-related , inter-SH2 domain [IPR032498]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PINIT domain [IPR023321]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PKHA4-7, PH domain [IPR040392]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKAA1, UBA-like autoinhibitory domain [IPR028797]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUB domain [IPR018997]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Palmitoyltransferase, DHHC domain [IPR001594]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Papain-like cysteine endopeptidase [IPR039417]", "Par3/HAL, N-terminal [IPR021922]", "Patatin-like phospholipase domain [IPR002641]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C1A, propeptide [IPR012599]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase like 2, U-box domain [IPR026951]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentrin/AKAP-450 centrosomal targeting domain [IPR019528]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 3-kinase regulatory subunit beta, SH3 domain [IPR035586]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D-like domain [IPR025202]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain [IPR045583]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Phox-associated domain [IPR003114]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, TIG domain 2 [IPR041362]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Plus-3 domain [IPR004343]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-mRNA-splicing factor SLU7 domain [IPR021715]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein MMS22-like, N-terminal [IPR029425]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein OS9-like domain [IPR012913]", "Protein RED, C-terminal [IPR012492]", "Protein SirB1, N-terminal [IPR032698]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein disulfide-isomerase A5, N-terminal TRX-like b domain [IPR041865]", "Protein furry, C-terminal [IPR045842]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Protocadherin [IPR013585]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAD51 interacting motif [IPR031419]", "RAP domain [IPR013584]", "RAVE complex protein Rav1 C-terminal [IPR022033]", "RBB1NT [IPR012603]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15B, RNA recognition motif 1 [IPR034475]", "RBM15B, RNA recognition motif 2 [IPR034535]", "RBM15B, RNA recognition motif 3 [IPR034536]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM8, RNA recognition motif [IPR033744]", "RBP-J/Cbf11/Cbf12, DNA binding [IPR015351]", "RBP-Jkappa, IPT domain [IPR038007]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RGS domain [IPR016137]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING finger protein 219, RING finger [IPR035691]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIO kinase [IPR000687]", "RIO2 kinase winged helix domain, N-terminal [IPR015285]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 2-O ribose methyltransferase, substrate binding [IPR013123]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II elongation factor ELL, N-terminal [IPR019464]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNF31, C-terminal [IPR041031]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rabaptin coiled-coil domain [IPR018514]", "Rabaptin, GTPase-Rab5 binding domain [IPR015390]", "Rad18, zinc finger UBZ4-type [IPR006642]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raf-like Ras-binding [IPR003116]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Rap1 Myb domain [IPR015010]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "RecQ mediated genome instability protein, DUF1767 [IPR033472]", "RecQ mediated genome instability protein, N-terminal [IPR013894]", "Receptor L-domain [IPR000494]", "Recq-mediated genome instability protein 1, C-terminal OB-fold domain [IPR032199]", "Redoxin [IPR013740]", "Regulator of G protein signalling-like domain [IPR015212]", "Rel homology dimerisation domain [IPR032397]", "Rel homology domain (RHD), DNA-binding domain [IPR011539]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Rhs repeat-associated core [IPR022385]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease H2 subunit B, wHTH domain [IPR019024]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal RNA-processing protein 7, C-terminal domain [IPR024326]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Rnh202, triple barrel domain [IPR041195]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rrp7, RRM-like N-terminal domain [IPR040447]", "Rrp7A, RNA recognition motif [IPR034890]", "Rubisco LSMT, substrate-binding domain [IPR015353]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SAM-dependent methyltransferase TRM5/TYW2-type [IPR030382]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SCAF4, RNA recognition motif [IPR034369]", "SCAF8, RNA recognition motif [IPR034370]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEPARIN core domain [IPR030397]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD2/Set2, SET domain [IPR044437]", "SETD3, SET domain [IPR044428]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGF29 tudor-like domain [IPR010750]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SH3PXD2, PX domain [IPR037961]", "SH3PXD2B, SH3 domain 1 [IPR035477]", "SH3PXD2B, SH3 domain 2 [IPR035478]", "SH3PXD2B, SH3 domain 3 [IPR035479]", "SH3PXD2B, SH3 domain 4 [IPR035480]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKICH domain [IPR041611]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMAP1-like, ArfGAP domain [IPR044732]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMG1, PIKK catalytic domain [IPR039414]", "SMYD3, SET domain [IPR044420]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX25, PX domain [IPR037899]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAR protein, homodimerisation region [IPR032377]", "STARD11, START domain [IPR041952]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Scaffold protein Nfu/NifU, N-terminal [IPR014824]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Sequestosome-1, PB1 domain [IPR034866]", "Sequestosome-1, UBA domain [IPR033741]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase MRCK beta, catalytic domain [IPR042718]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-protein kinase Rio2 [IPR030484]", "Serine/threonine-protein kinase SMG1, N-terminal [IPR035175]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set1A, RNA recognition motif [IPR034467]", "Set2 Rpb1 interacting domain [IPR013257]", "Siah interacting protein, N-terminal [IPR015120]", "Sialate O-acetylesterase domain [IPR005181]", "Sialidase [IPR011040]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Signal transduction histidine kinase-related protein, C-terminal [IPR004358]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein LSm5 [IPR033871]", "Sm-like protein Lsm3 [IPR034105]", "Sm-like protein Lsm4 [IPR034101]", "Sm-like protein Lsm8 [IPR034103]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Somatomedin B domain [IPR001212]", "Somatomedin B, chordata [IPR020436]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin 4, PX domain [IPR034902]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, C-terminal [IPR013937]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-4, BAR domain [IPR037430]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Sperm-specific antigen 2, C-terminal [IPR029326]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Sphingomyelin phosphodiesterase, C-terminal domain [IPR045473]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Strawberry notch, AAA domain [IPR039187]", "Strawberry notch, helicase C domain [IPR026937]", "Strictosidine synthase, conserved region [IPR018119]", "Stromal interaction molecule 1, SAM domain [IPR037609]", "Stromal interaction molecule, Orai1-activating region [IPR032393]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Sushi/SCR/CCP domain [IPR000436]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synaptotagmin-like, mitochondrial and lipid-binding domain [IPR040885]", "Syndetin, C-terminal [IPR019514]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "Syntrophin, split Pleckstrin homology (PH) domain [IPR041428]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA element modulatory factor 1, TATA binding [IPR022091]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TDRD7, third LOTUS domain [IPR037978]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TFIIH p62 subunit, N-terminal [IPR013876]", "TGS [IPR004095]", "THADA/TRM732, DUF2428 [IPR019442]", "THAP-type zinc finger [IPR006612]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TNF receptor-associated factor 2, MATH domain [IPR037305]", "TNF receptor-associated factor, BIRC3 binding domain [IPR032070]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TROVE domain [IPR008858]", "TSG101 and ALIX binding domain of CEP55 [IPR022008]", "TUG ubiquitin-like domain [IPR021569]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "TauD/TfdA-like domain [IPR003819]", "Tectonic domain [IPR011677]", "Telomerase activating protein Est1, N-terminal [IPR019458]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Telomere-length maintenance and DNA damage repair [IPR021668]", "Teneurin intracellular, N-terminal [IPR009471]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tfc3, extended winged-helix domain [IPR035625]", "Thg1 C-terminal domain [IPR025845]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Thyroglobulin type-1 [IPR000716]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Toll-interacting protein, C2 domain [IPR037301]", "Toll-interacting protein, CUE domain [IPR041799]", "Toll/interleukin-1 receptor homology (TIR) domain [IPR000157]", "TopBP1, first BRCT domain [IPR044737]", "Topoisomerase I C-terminal domain [IPR025834]", "Tox-GHH domain [IPR028916]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor 20, ePHD domain [IPR041972]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "Tubulin epsilon and delta complex protein 1 domain [IPR027996]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC1, UBA domain 1 [IPR041926]", "UBAC1, UBA domain 2 [IPR041927]", "UBAC2, UBA domain [IPR041928]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-N-acetylglucosamine 2-epimerase domain [IPR003331]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UDP-glucuronate decarboxylase N-terminal [IPR021761]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UMA domain [IPR023340]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "UVR domain [IPR001943]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal [IPR032197]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 38 [IPR033840]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Upstream-binding protein 1, SAM domain [IPR037600]", "Uracil-DNA glycosylase-like [IPR005122]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VASt domain [IPR031968]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein 14, C-terminal Fig4-binding domain [IPR021841]", "Vacuolar protein sorting protein 11, C-terminal [IPR024763]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar protein sorting-associated protein 54, N-terminal [IPR019515]", "Vacuolar protein sorting-associated, VPS28, C-terminal [IPR017899]", "Vacuolar protein sorting-associated, VPS28, N-terminal [IPR017898]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 [IPR019452]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 [IPR019453]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Very large inducible GTPASE (VLIG)-type guanine nucleotide-binding (G) domain [IPR030383]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vesicle transport v-SNARE, N-terminal [IPR007705]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vps72/YL1, C-terminal [IPR013272]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASP family, EVH1 domain [IPR033927]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WRNIP1, ubiquitin-binding domain [IPR040539]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, D1 domain [IPR040992]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YegS/DAGK, C-terminal domain [IPR045540]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "YrdC-like domain [IPR006070]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, AN1-type [IPR000058]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C2HC5-type [IPR009349]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, C5HC2-type [IPR004198]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FCS-type [IPR012313]", "Zinc finger, FLYWCH-type [IPR007588]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, TRAF-type [IPR001293]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc finger, nuclear hormone receptor-type [IPR001628]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zinc-ribbon domain [IPR026870]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "bMERB domain [IPR022735]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA decapping enzyme 2 , NUDIX hydrolase domain [IPR044099]", "mRNA decapping protein 2, Box A domain [IPR007722]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "mRNA-decapping enzyme, C-terminal [IPR031953]", "p115RhoGEF, RGS domain [IPR037887]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNAHis guanylyltransferase catalytic domain [IPR024956]", "tRNase Z endonuclease [IPR027794]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAK1", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACE2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAR", "ADAT3", "ADCY3", "ADD1", "ADD2", "ADD3", "ADGRE5", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFF4", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "APIP", "APLP2", "APMAP", "APP", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARID4B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6", "ARL8B", "ARMC10", "ARMCX3", "ARMT1", "ARSA", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASNSD1", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG7", "ATIC", "ATL2", "ATL3", "ATM", "ATP11C", "ATP13A1", "ATP13A2", "ATP13A3", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATP7A", "ATRN", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B4GALT3", "BAG2", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANP", "BAP1", "BAP18", "BARD1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS3", "BCKDHB", "BCKDK", "BCL10", "BCOR", "BCR", "BCS1L", "BEND3", "BET1", "BIRC6", "BLM", "BLVRA", "BMS1", "BOP1", "BPHL", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BTN2A1", "BUB1B", "BUD23", "BZW1", "BZW2", "C1orf35", "C2CD2", "C2CD5", "C3orf58", "CABIN1", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CBL", "CBX1", "CBX2", "CBX3", "CBX4", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC97", "CCNB1", "CCNK", "CCZ1B", "CD109", "CD276", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDK7", "CDK9", "CDKAL1", "CDKN2AIP", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPV", "CEP170", "CEP290", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHTF18", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLIC1", "CLINT1", "CLK2", "CLK3", "CLPB", "CLPX", "CLSTN3", "CLTC", "CLUH", "CMBL", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNPY2", "COA3", "COASY", "COCH", "COG4", "COIL", "COL4A3BP", "COLEC12", "COMMD8", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX6C", "CPD", "CPE", "CPNE1", "CPNE3", "CPNE8", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRAT", "CRK", "CRKL", "CROT", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTBS", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSB", "CTSC", "CTSF", "CTSL", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC22", "CWC27", "CWF19L1", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "DAG1", "DAGLB", "DARS", "DARS2", "DAXX", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCP1A", "DCP1B", "DCP2", "DCTD", "DCTN1", "DCUN1D5", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMAP1", "DMD", "DMXL1", "DMXL2", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC2H1", "EARS2", "EBP", "ECE1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP3", "EMC1", "EMC7", "EMC8", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERI1", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM192A", "FAM208A", "FAM3C", "FAM49B", "FAM83D", "FAM8A1", "FAM91A1", "FANCA", "FANCI", "FAR1", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FAT1", "FBXO21", "FBXO22", "FBXO38", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FNBP1", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FREM2", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALE", "GALK1", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDE1", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GIT1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNE", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPS1", "GPT2", "GRAMD1A", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGXB4", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPRT1", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "IAH1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPACT", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISOC1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPK1", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAK1", "KARS", "KAT5", "KAT7", "KATNA1", "KCTD10", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0100", "KIAA0319L", "KIAA0391", "KIAA1147", "KIAA1468", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "KIN", "KIRREL1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "L2HGDH", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDB1", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN2", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRIG1", "LRIG2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LRRC8C", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYPLA2", "LYSMD3", "LZIC", "M6PR", "MACF1", "MACROD1", "MAGED1", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANBA", "MANF", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBD3", "MBLAC2", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MED12", "MED25", "MEPCE", "METAP2", "METTL13", "METTL7B", "MFAP1", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD8", "MGA", "MGRN1", "MIA2", "MIA3", "MICAL3", "MICALL1", "MICU1", "MICU2", "MID1", "MINDY3", "MIPEP", "MKI67", "MKL2", "MKRN2", "MLEC", "MMAB", "MMS19", "MMS22L", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPHOSPH8", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRM3", "MRPL11", "MRPL12", "MRPL15", "MRPL16", "MRPL24", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL58", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVD", "MVK", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA40", "NAA50", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCEH1", "NCKIPSD", "NCL", "NCLN", "NCOA4", "NCOR1", "NCSTN", "NDC80", "NDUFA10", "NDUFA2", "NDUFA8", "NDUFA9", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFE", "NEMF", "NENF", "NEO1", "NEPRO", "NES", "NEU1", "NF1", "NF2", "NFATC2IP", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NID1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME4", "NMT1", "NNT", "NOA1", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "OBSL1", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK2", "PALD1", "PALLD", "PAM", "PAN2", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDXK", "PDZD8", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4K2B", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGG", "PIGO", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PINX1", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLAA", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLEKHA7", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNA3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP4R1", "PPP4R3A", "PPP5C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKACA", "PRKACB", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPN1", "PTPN11", "PTPN13", "PTPN23", "PTPRF", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PXN", "PYCR1", "PYCR2", "QARS", "QKI", "QRICH1", "QRSL1", "QSER1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB31", "RAB32", "RAB33B", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RAD54L2", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1CC1", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "RELA", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOK2", "RIOX1", "RIPK1", "RMI1", "RMND1", "RNASEH2A", "RNASEH2B", "RNF14", "RNF149", "RNF20", "RNF213", "RNF219", "RNF31", "RNF40", "RNMT", "RNPEP", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP25L", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRP12", "RRP7A", "RSF1", "RSL24D1", "RTCA", "RTF1", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP30", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SBNO1", "SC5D", "SCAF11", "SCAF4", "SCAF8", "SCAP", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SCYL1", "SCYL2", "SDAD1", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SENP6", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGSH", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SIAE", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A2", "SLC27A4", "SLC2A1", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG6", "SMN1*", "SMNDC1", "SMPDL3A", "SMPDL3B", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX25", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORL1", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPECC1L", "SPEN", "SPHK2", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSFA2", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STK3", "STK4", "STOM", "STOML2", "STRBP", "STRIP1", "STUB1", "STX12", "STX18", "STX5", "STX6", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYDE1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6L", "TAGLN2", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TAX1BP1", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCTN3", "TDRD7", "TDRKH", "TECR", "TEDC1", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX2", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THADA", "THAP11", "THG1L", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM205", "TMEM97", "TMF1", "TMLHE", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOM1L2", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TPBG", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIO", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT5", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSR1", "TSR3", "TST", "TSTA3", "TTC4", "TTF2", "TTK", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP1", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UGDH", "UGGT1", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "URB1", "URB2", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP32", "USP33", "USP34", "USP36", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "UXS1", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VLDLR", "VPS11", "VPS13A", "VPS13C", "VPS18", "VPS28", "VPS29", "VPS37B", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "VTI1B", "WAPL", "WARS", "WASF2", "WASL", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WNK1", "WNK2", "WRN", "WRNIP1", "WWP2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YAP1", "YARS", "YBX1", "YES1", "YIPF4", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCCHC9", "ZDHHC13", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF131", "ZNF277", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512", "ZNF598", "ZNF622", "ZNF638", "ZNF644", "ZNF687", "ZNF830", "ZPR1", "ZYX"], "leading_proteins": ["AARS2", "ABCB1", "ABCC1", "ABCD4", "ABCF3", "ADGRE5", "AKAP8", "ALCAM", "ALG5", "ANKFY1", "ANKLE2", "ANKS1A", "ANP32A", "AP1M1", "AP2M1", "APBB1", "APP", "ARCN1", "ARSA", "ASNSD1", "ATP13A1", "ATP13A2", "ATP13A3", "ATP2B1", "ATP2C1", "ATP7A", "ATRN", "BAIAP2", "BCKDK", "BRAP", "BSG", "BTN2A1", "CADM1", "CALCOCO2", "CALM3", "CALU", "CASK", "CBX1", "CBX3", "CBX4", "CCNB1", "CD276", "CD47", "CELF1", "CERS2", "CIRBP", "CLCN3", "CLCN7", "CLSTN3", "CNNM3", "COCH", "COLEC12", "CPD", "CPT2", "CRK", "CSRP2", "CTSB", "CTSC", "CTSL", "CTTN", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "DCTN1", "DHCR24", "DLG1", "DMXL1", "DNAJA1", "DNAJA2", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNM1", "DNM1L", "DNMBP", "DOCK1", "DOCK6", "DSC3", "DVL2", "EEF1D", "EFCAB14", "EGFR", "EHD1", "EHD4", "EHMT2", "EIF4B", "EIF4H", "EIF5", "ELMO2", "ENDOD1", "ENPP1", "EPHA2", "EPHA7", "ERGIC3", "ESYT2", "EWSR1", "EXOSC1", "F11R", "FAT1", "FBXO38", "FCGRT", "FHL1", "FKBP14", "FKBP7", "FLII", "FLOT1", "FMR1", "FNBP1", "FUCA2", "FUS", "FXR1", "FXR2", "GALNS", "GALNT1", "GALNT7", "GINS4", "GLB1", "GM2A", "GNS", "GPAM", "GPD2", "GRB2", "GSTCD", "GTF2B", "HDAC1", "HDGF", "HDGFL2", "HEXA", "HGS", "HIP1R", "HLA-A", "HLA-B", "HLA-C", "HNRNPA0", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPL", "HNRNPLL", "HNRNPR", "HNRNPUL1", "HNRNPUL2", "HSD17B4", "HSDL2", "IDH2", "IFNGR1", "IGF2BP2", "IGF2R", "IMP3", "ITCH", "ITGA2", "ITGB1", "ITM2B", "JAK1", "KAT7", "KATNA1", "KCTD12", "KEAP1", "KHDRBS1", "KHSRP", "KIRREL1", "L2HGDH", "LASP1", "LDLR", "LGALS3BP", "LIMA1", "LMAN2", "LMO7", "LONP1", "LRIG2", "LRP1", "LRP2", "LSM14B", "MAK16", "MAN2B1", "MANBA", "MATR3", "MCAM", "MCUB", "MFGE8", "MFN1", "MFN2", "MFSD8", "MIA2", "MICAL3", "MICALL1", "MOSPD2", "MPP1", "MPP2", "MPP6", "MPP7", "MRC2", "MRPL16", "MRPL43", "MRPS25", "MSH3", "MSH6", "MSMO1", "MTIF2", "MTMR2", "MTMR4", "NCAM1", "NECTIN2", "NEDD4", "NEO1", "NID1", "NISCH", "NOTCH2", "NUCB1", "NUCB2", "NUDCD3", "OCLN", "OLA1", "OS9", "P3H1", "P4HA2", "PABPC4", "PACSIN3", "PALD1", "PCDH7", "PCYOX1", "PDCD6IP", "PDIA5", "PDK3", "PDLIM5", "PDLIM7", "PDZD8", "PHKB", "PI4K2B", "PIK3R2", "PLCG2", "PLOD1", "PLOD2", "PLXNA3", "POLDIP2", "POR", "PPIL4", "PRDX3", "PRKAR1A", "PROCR", "PSPC1", "PTBP2", "PTK7", "PTPN23", "PTPRF", "PUF60", "PXN", "PYCR2", "QSOX2", "RABGAP1", "RBM10", "RBM12B", "RBM3", "RBM4", "RBM45", "RBM5", "RBMX", "RBMXL1", "RCN1", "RCN2", "RHOT1", "ROBO1", "RPS9", "RTN3", "RTN4", "RTN4IP1", "S100A11", "SACS", "SAMHD1", "SDCBP", "SEC23A", "SEC23B", "SEC24A", "SEC24C", "SEPT2", "SEPT9", "SERPINB1", "SERPINH1", "SEZ6L2", "SFPQ", "SIRT2", "SLC12A2", "SLC12A9", "SLC3A2", "SLC4A7", "SLIRP", "SLIT2", "SMARCA1", "SMNDC1", "SMPDL3B", "SNAP23", "SNAP29", "SNAP47", "SNTB2", "SNX2", "SNX25", "SNX27", "SORL1", "SRSF1", "SRSF10", "SRSF5", "SRSF7", "SRSF9", "STAG1", "STAM", "STK3", "STOM", "STX12", "STX6", "STX7", "STX8", "SV2A", "SYNCRIP", "TAF15", "TAP2", "TAX1BP1", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TES", "TEX2", "TFRC", "TIA1", "TIAL1", "TIMM44", "TJP1", "TLCD1", "TMPO", "TMPPE", "TMX3", "TMX4", "TOM1L2", "TOP3A", "TPBG", "TRA2A", "TRA2B", "TRAM1", "TUBB", "TUBB2B", "TXNDC12", "TXNDC16", "TXNDC9", "TXNL1", "UBE3A", "ULK3", "USP22", "USP33", "USP39", "UXS1", "VAPA", "VIM", "VLDLR", "VPS4A", "VPS4B", "VPS51", "VTI1B", "WBP2", "YES1", "ZADH2", "ZCCHC3", "ZMYM2", "ZYX"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ff8d3a033867d468eb862b4d6470624bf1e78d0e --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "P-type ATPase [IPR001757]", "1": "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..eed0ab41ac2f90aa90fa494aaf9285c193725191 --- /dev/null +++ b/interpro_family/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d996b0d8f180f625358c231defe54aebb8f06f169db72ab6b12c440876c19b8f +size 191487 diff --git a/interpro_family/advanced/plot_1.png b/interpro_family/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..b654f97b51de1f7341a9edf69bb8f9ab0ed5514f --- /dev/null +++ b/interpro_family/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0f83319ddd4af9fbf7bc3625178b176d68e4a72a601964a044b229c3b1b6fe36 +size 187980 diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ff8d3a033867d468eb862b4d6470624bf1e78d0e --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "P-type ATPase [IPR001757]", "1": "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..4e669dead5f0e71eb2bd34bd89bbd19cd03a55a6 --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4b5be3e73815a9e41bba45416a1756a928efae0fd0c38e50b8cc5f9a04e1f264 +size 131035 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..aa461ca91a81dd4c34ef760af89c4b99ced28905 --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:218f65688cc3dd7b66328291b6888feb20de2ee389a86b2ef833e57865e804b2 +size 138636 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..aa307fc4f9b023ea93b8cf05f6239797fd5185da --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:526e43524925cc9626d989d8490c94b628d3fffcee596c24f83367b37f97e0a7 +size 362282 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1de0036811e2fe1d92cac05bbfb0de3dfe38d88b --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +P-type ATPase [IPR001757] 5 10 2.116251098265392 0.0343234574091513 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.1184088205118859 1.0 1.0 0.4160065505344545 0.0034687949642114 +Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019] 5 6 2.0741771769645085 0.0380628590425813 2.2815533980582523 4.327669902912621 -0.2210829368206083 0.5388631009388022 1.380639191550687 1.1285833579715243 0.9314689024130508 0.3098435129808265 1.0 1.0 1.0 1.0 0.0019736987849612 +Syntaxin [IPR045242] 3 5 1.9986855684239968 0.0456423854450704 2.674757281553398 5.815533980582524 0.7134969984167514 0.3462495636510407 1.4434464182805606 1.4295601388514203 1.142372356309129 0.3001529293380739 0.0004243821515525 1.0 1.0 0.0041470760753771 0.0036942631899424 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..eeeac50d325e839099b374dcdc84c123b5317db2 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 2825, + "title": "Average number of proteins per term", + "value": 1.2892035398230088 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c29cea3b0d667c993290d775110237c8cd90e441 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d57a551a9c00ad78046a26b1488442df1254d108 --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,155 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase [IPR001757] 0.7690897818269417 2.116251098265392 0.0343234574091513 1.0 0.1845540087731126 10 Q9H7F0,Q04656,P98194,Q9HD20,Q9NQ11 5 +Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019] 0.8480774401720848 2.0741771769645085 0.0380628590425813 1.0 0.189591643231076 6 P08754,P09471,Q14344,P04899,P63096 5 +Syntaxin [IPR045242] 0.8544199442969387 1.9986855684239968 0.0456423854450704 1.0 0.201265038632972 5 Q86Y82,O43752,Q9UNK0 3 +G-protein alpha subunit, group I [IPR001408] 0.8785272776135451 1.8938757861912028 0.058241499185172 1.0 0.2231497439394084 4 P04899,P08754,P63096 3 +Eukaryotic porin/Tom40 [IPR027246] 0.8590988006541573 1.816815865669004 0.0692453126408971 1.0 0.2395260254644102 4 P21796 1 +Palmitoyl protein thioesterase [IPR002472] 0.9903303787268344 1.7772879526804426 0.0755208747883267 1.0 0.2498391386481813 2 Q9UMR5 1 +Beta-hexosaminidase [IPR025705] 0.9871071716357774 1.7641499753585472 0.0777067323945877 1.0 0.2498520487806714 2 P06865 1 +Amyloidogenic glycoprotein [IPR008155] 0.9863013698630148 1.7608645874052056 0.0782613249216437 1.0 0.250666942067623 2 P05067 1 +Acyltransferase ChoActase/COT/CPT [IPR000542] 0.8438251024199097 1.7559189614788706 0.0791022468105016 1.0 0.2519631455474564 4 P23786 1 +Integral membrane protein 2 [IPR040145] 0.9803921568627472 1.736761335826979 0.0824293062957131 1.0 0.2573458628146425 2 Q9Y287 1 +Tetraspanin/Peripherin [IPR018499] 0.9779747515444532 1.7268958823386922 0.0841863640804914 1.0 0.2589276953271113 2 O60637 1 +Tetraspanin, animals [IPR000301] 0.9779747515444532 1.7268958823386922 0.0841863640804914 1.0 0.2589276953271113 2 O60637 1 +Lysosome-associated membrane glycoprotein [IPR002000] 0.9766317485898496 1.7214138791954725 0.0851757475008034 1.0 0.2601313369619133 2 P13473 1 +Alpha-L-fucosidase, metazoa-type [IPR016286] 0.9755573462261644 1.7170276793812491 0.0859741147122581 1.0 0.2608774157487961 2 Q9BTY2 1 +Glycoside hydrolase, family 29 [IPR000933] 0.9755573462261644 1.7170276793812491 0.0859741147122581 1.0 0.2608774157487961 2 Q9BTY2 1 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.9793121977431484 1.6930116933471524 0.090453241457068 1.0 0.2672912208328631 3 Q9HB40,P10619 2 +CD36 family [IPR002159] 0.9591727101799656 1.6500802290276508 0.0989265279224544 1.0 0.2800893846825392 2 Q14108 1 +Acid sphingomyelinase-like phosphodiesterase, predicted [IPR017064] 0.954875100725223 1.632505223417715 0.1025730990062128 1.0 0.2871171125659111 2 Q92485 1 +Chloride channel, voltage gated [IPR001807] 0.9500402900886432 1.6127277104972766 0.1068036774892533 1.0 0.2924737911802598 2 P51790 1 +Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550] 0.9486972871340318 1.6072330476189025 0.1080032550654339 1.0 0.292530388839742 2 Q96KQ7 1 +Ephrin receptor type-A /type-B [IPR016257] 0.946011281224822 1.5962427046369323 0.1104346165715912 1.0 0.2957135467438344 2 Q15375 1 +Sulfotransferase [IPR005331] 0.9449368788611356 1.5918462246970269 0.1114192609086308 1.0 0.2969428415725303 2 Q7LGA3 1 +Chondroitin N-acetylgalactosaminyltransferase [IPR008428] 0.9374160623153422 1.561066724121997 0.1185080083912932 1.0 0.3046270461377648 2 Q8N6G5 1 +Nucleosome assembly protein (NAP) [IPR002164] 0.788392054607378 1.532906467712931 0.1252989020695742 1.0 0.3143600340555482 4 Q99733,P55209 2 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.9352498656636208 1.5265370258069928 0.1268761767220521 1.0 0.3157931270835217 3 Q8NBN3,Q5VW38 2 +Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756] 0.9285522428149336 1.5247864429993183 0.1273123724227263 1.0 0.3161682193978458 2 Q8TCG2 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.9258662369057208 1.5137926506597938 0.1300784372018213 1.0 0.3198186119191865 2 Q93050 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.9258662369057208 1.5137926506597938 0.1300784372018213 1.0 0.3198186119191865 2 Q93050 1 +Integrin alpha chain [IPR000413] 0.9223744292237442 1.499501559236722 0.1337435645095293 1.0 0.3239859166243556 2 P17301 1 +Major facilitator, sugar transporter-like [IPR005828] 0.9167338168144048 1.476419275703749 0.1398313712263577 1.0 0.331627806825688 2 Q7L0J3 1 +P-type ATPase, subfamily V [IPR006544] 0.9156367544330996 1.4522526682102046 0.1464313629604778 1.0 0.3412790334411406 3 Q9HD20,Q9H7F0 2 +Ancient conserved domain protein family [IPR045095] 0.9078699973139994 1.4401606526138335 0.1498219524995192 1.0 0.3450601115036233 2 Q8NE01 1 +Flotillin family [IPR027705] 0.9070641955412286 1.4368655145961755 0.1507562103939372 1.0 0.3462490198072136 2 O75955 1 +HnRNP R/Q splicing factor [IPR006535] 0.9059897931775444 1.4324723351227864 0.152008689979594 1.0 0.3477121855808528 2 O60506 1 +Desmosomal cadherin [IPR009122] 0.90491539081387 1.4280795587069943 0.1532689603959385 1.0 0.3488999299907545 2 Q14574 1 +Fragile X mental retardation syndrome-related protein [IPR040148] 0.9013970983342282 1.3983082084378828 0.1620205339866283 1.0 0.359136403242984 3 P51116,P51114 2 +Nonaspanin (TM9SF) [IPR004240] 0.9000537345513153 1.3932199236139695 0.1635532967124171 1.0 0.3618152413567568 3 Q99805,Q9HD45 2 +Glycoside hydrolase, family 35 [IPR001944] 0.8957829707225484 1.390759900093303 0.1642982467232392 1.0 0.3623282958572606 2 P16278 1 +Beta-galactosidase 1-like [IPR026283] 0.8957829707225484 1.390759900093303 0.1642982467232392 1.0 0.3623282958572606 2 P16278 1 +Plexin family [IPR031148] 0.8863819500402939 1.35238702588104 0.1762515376629552 1.0 0.374909109954083 2 P51805 1 +Cytochrome P450 [IPR001128] 0.8775181305398974 1.3162605218719745 0.188086616379342 1.0 0.3888827411784414 2 Q16850 1 +Tubulin [IPR000217] 0.7337477658983322 1.3110557913124314 0.1898389151782589 1.0 0.3900326802753319 4 P07437,Q9BVA1 2 +Beta tubulin [IPR002453] 0.7337477658983325 1.3110557913124314 0.1898389151782589 1.0 0.3900326802753319 4 P07437,Q9BVA1 2 +Major facilitator superfamily [IPR011701] 0.6824614272031432 1.2884642921387082 0.1975843910655601 1.0 0.399553260386691 5 Q7L0J3 1 +TAF15/EWS/TLS family [IPR034870] 0.8675443310048346 1.2702354259280062 0.2040007821627409 1.0 0.4072035175577112 3 P35637,Q92804 2 +Porin, eukaryotic type [IPR001925] 0.8672049954493299 1.2689541042105188 0.2044574337328311 1.0 0.4076162669691234 3 P21796 1 +Nucleobindin [IPR040250] 0.8544184797206699 1.2224508459637988 0.2215371812651454 1.0 0.4274880717718824 2 P80303 1 +SLC12A transporter family [IPR004842] 0.8495432563138079 1.2023721714693427 0.2292193660914638 1.0 0.4340111992013307 3 Q9BXP2,P55011 2 +cAMP-dependent protein kinase catalytic subunit [IPR044109] 0.848240666129476 1.1974681227794273 0.2311241451756216 1.0 0.4355926720469772 2 P22694 1 +NSF attachment protein [IPR000744] 0.8468976631748553 1.1920441206048644 0.2332439457757464 1.0 0.4383992992790976 2 Q99747 1 +Isocitrate dehydrogenase NADP-dependent [IPR004790] 0.8431372549019742 1.1768710869361834 0.2392469638577772 1.0 0.4438710123247233 2 P48735 1 +E3 ubiquitin-protein ligase, SMURF1 type [IPR024928] 0.8417942519473641 1.1714573802019237 0.2414149795198614 1.0 0.4449574438143835 2 Q96J02 1 +Dynamin [IPR022812] 0.6938541709332182 1.1490041466681908 0.2505542708015198 1.0 0.4566553645253506 4 Q05193,O00429 2 +Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284] 0.8321246306742057 1.1325663192787887 0.2573964193220364 1.0 0.4628547960437637 2 Q9HCL2 1 +Purine-rich element binding protein family [IPR006628] 0.8286328229922217 1.1185629023108592 0.2633266573417832 1.0 0.4693361558299921 2 Q96QR8 1 +Myotubularin family [IPR030564] 0.8160256996698135 1.0768559151656834 0.2815446406042596 1.0 0.4891535115049407 3 Q9NYA4 1 +Mitochondrial carrier UCP-like [IPR002030] 0.8178887993553761 1.0756263183412091 0.2820944121366571 1.0 0.4896376946462025 2 Q9H2D1 1 +Prenylcysteine oxidase [IPR017046] 0.8127853881278733 1.0553183086056928 0.2912797703895109 1.0 0.4998050032086718 2 Q9UHG3 1 +Endoplasmic reticulum vesicle transporter [IPR045888] 0.8052645715820757 1.0255032247535787 0.305125804609357 1.0 0.5130835702508533 2 Q9Y282 1 +A-kinase anchoring protein 95 (AKAP95) [IPR007071] 0.800727648982962 1.0200945868852287 0.3076836037639818 1.0 0.5142249468453771 3 O43823 1 +Cleft lip and palate transmembrane 1 [IPR008429] 0.8036529680365296 1.0191327545548157 0.3081399458755496 1.0 0.5142249468453771 2 Q96KA5 1 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.8036529680365296 1.0191327545548157 0.3081399458755496 1.0 0.5142249468453771 2 Q96KA5 1 +TB2/DP1/HVA22-related protein [IPR004345] 0.7952411272658837 0.9998407024227348 0.3173876047034649 1.0 0.5235859259293627 3 Q9H6H4 1 +H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504] 0.7867311308084852 0.9526789793223778 0.3407527470515701 1.0 0.5460161715375413 2 Q96HR8 1 +Membrane bound O-acyl transferase, MBOAT [IPR004299] 0.7840451248992717 0.942210078399516 0.3460850950049503 1.0 0.5520555580965469 2 P35610 1 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.7781764059695659 0.937252878371066 0.3486284955244754 1.0 0.5539232282658284 3 Q99436 1 +Bicarbonate transporter, eukaryotic [IPR003020] 0.7816277195810032 0.9328081777224108 0.3509190181693884 1.0 0.5558929737966662 2 Q9Y6M7 1 +Type 1 protein exporter [IPR039421] 0.5793801873661143 0.9325567503595223 0.3510488726560186 1.0 0.5558929737966662 6 P08183,Q03519 2 +Snf7 family [IPR005024] 0.6389168166586036 0.9282545475800964 0.3532755452787284 1.0 0.5573749012933984 4 Q9Y3E7 1 +Phosphorylase kinase alpha/beta subunit [IPR008734] 0.7770615095353421 0.9151028190410894 0.3601376551976436 1.0 0.5641622275636334 2 Q93100 1 +Prolyl 4-hydroxylase [IPR045054] 0.776255707762576 0.9119858459594296 0.3617761685224332 1.0 0.5657238957191677 2 O15460 1 +Plakophilin/Delta catenin [IPR028435] 0.7694047458809881 0.9053528312794084 0.3652784960243811 1.0 0.5682333432097338 3 O00192 1 +Sec1-like protein [IPR001619] 0.5466246166490057 0.9036166991848412 0.3661986833488844 1.0 0.5690381080641355 7 O00186,Q15833,Q8WU76,Q9H267 4 +Tropomodulin [IPR004934] 0.7730325006715024 0.8995411341439368 0.36836449598756 1.0 0.571460571754452 2 P28289 1 +Mitofusin family [IPR027094] 0.771689497716892 0.8943669858335862 0.3711255704013494 1.0 0.5738531671504171 2 Q8IWA4 1 +C-terminal binding protein [IPR043322] 0.7582594681708508 0.8430086508972064 0.3992236055904063 1.0 0.597671799572283 2 P56545 1 +Sodium/potassium-transporting ATPase subunit beta [IPR000402] 0.7477840451249188 0.8034741050929465 0.4217007579441336 1.0 0.6169366344858507 2 P05026 1 +Vacuolar protein-sorting protein Bro1-like [IPR045251] 0.7408004297609463 0.7773990205808647 0.4369233901251683 1.0 0.6310371048586915 2 Q9H3S7 1 +MCU family [IPR039055] 0.7378458232608179 0.7664392554525533 0.4434149827559097 1.0 0.6368313809280352 2 Q9NWR8 1 +SNX17/27/31 [IPR037831] 0.7338168143969951 0.7515659897029988 0.452312102551085 1.0 0.6437187353686726 2 Q96L92 1 +Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591] 0.5910106418055818 0.7414464578957757 0.4584227845427366 1.0 0.6481703535201356 4 Q5H8A4,Q9Y6X5 2 +Protein OS-9-like [IPR045149] 0.7257587966693577 0.7220792137243564 0.4702457771044828 1.0 0.6594125983659783 2 Q13438 1 +Protein transport protein Sec23 [IPR037364] 0.7233413913510618 0.7133035213373993 0.4756579589627923 1.0 0.6629174810408921 2 Q15436 1 +Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081] 0.6945213797616147 0.643791716091918 0.5197105062405956 1.0 0.6931927196079709 3 P39687 1 +Calreticulin/calnexin [IPR001580] 0.6874369710235905 0.6203579261243112 0.5350221660092507 1.0 0.7033213676017371 3 O14967 1 +Vacuolar protein sorting-associated protein 33 [IPR027121] 0.6935267257587953 0.6080476116651178 0.5431558965491436 1.0 0.7077561843871452 2 Q9H267 1 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.6889605157131512 0.5924614991359014 0.5535415949090854 1.0 0.715767134644237 2 O75880 1 +Copper chaperone SCO1/SenC [IPR003782] 0.6889605157131512 0.5924614991359014 0.5535415949090854 1.0 0.715767134644237 2 O75880 1 +Target of Myb protein 1 [IPR014645] 0.6886919151222309 0.5915494690165872 0.5541523196753775 1.0 0.7157708968883062 2 Q6ZVM7 1 +Small GTPase, Ras-type [IPR020849] 0.5427660427345204 0.5634620636117044 0.5731202856322342 1.0 0.7266871627867282 4 P11233 1 +P-type ATPase, subfamily IIB [IPR006408] 0.6782164920762799 0.5564112661192306 0.5779297389436691 1.0 0.7298397463191171 2 P20020 1 +Cohesin subunit Scc3/SA [IPR039662] 0.6655922643029781 0.5152416552018569 0.6063841640792809 1.0 0.7472327672842882 2 Q8WVM7 1 +HnRNP-L/PTB [IPR006536] 0.5286213383499148 0.5140579133665141 0.6072115011143606 1.0 0.7473012561325261 4 Q8WVV9,Q9UKA9,P14866 3 +Prefoldin beta-like [IPR002777] 0.52841580063353 0.5133511366534671 0.6077057193812472 1.0 0.7473960197004891 4 O15212 1 +Ribosomal protein L22/L17 [IPR001063] 0.6591458501208867 0.4947468790873141 0.6207788057941561 1.0 0.7555795460441581 2 Q9NWU5 1 +Dedicator of cytokinesis [IPR026791] 0.6392712764531 0.4694183941861012 0.6387706029922637 1.0 0.7680923511715193 3 Q14185 1 +FAM105 [IPR023235] 0.6438356164383511 0.4476034728148418 0.6544393963719164 1.0 0.7781108142889999 2 Q9NUU6 1 +UBAP2/protein lingerer [IPR022166] 0.5876980929358073 0.2958031269152497 0.7673804348768551 1.0 0.8366845729552743 2 Q14157 1 +Dephospho-CoA kinase [IPR001977] 0.5860864893902715 0.2919851989756625 0.7702979406215176 1.0 0.8385709758211125 2 Q13057 1 +Glycosyl transferase, family 8 [IPR002495] 0.5704199067563834 0.2865625153214089 0.7744473195801012 1.0 0.8417137848523342 3 Q68CQ7 1 +Protein disulphide isomerase [IPR005792] 0.5701235894680197 0.2858766665928357 0.7749725856286447 1.0 0.8417137848523342 3 P30101,P13667 2 +Sla2 family [IPR030224] 0.5815202793446103 0.2813425260466373 0.7784476958885285 1.0 0.8432605451349695 2 O75146 1 +Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100] 0.5793714746172394 0.2764242126962946 0.7822222618830041 1.0 0.8456861422960148 2 P00390 1 +Tropomyosin [IPR000533] 0.5591080064481377 0.2610572520382129 0.7940483567703112 1.0 0.8540120467736584 3 P67936,P06753 2 +Peptidase C69, dipeptidase A [IPR005322] 0.555197421434325 0.2251428001537594 0.8218681858708856 1.0 0.873612950131066 2 Q0VDG4 1 +Aminotransferase class IV [IPR001544] 0.5549288208433996 0.2246153461193461 0.822278525450798 1.0 0.873612950131066 2 O15382 1 +Branched-chain amino acid aminotransferase II [IPR005786] 0.5549288208433996 0.2246153461193461 0.822278525450798 1.0 0.873612950131066 2 O15382 1 +Branched-chain aminotransferase [IPR033939] 0.5549288208433996 0.2246153461193461 0.822278525450798 1.0 0.873612950131066 2 O15382 1 +Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756] 0.5490196078431401 0.2132492100464517 0.8311325868244754 1.0 0.880041063635361 2 Q8TB37 1 +Mrp/NBP35 ATP-binding protein [IPR019591] 0.5490196078431401 0.2132492100464517 0.8311325868244754 1.0 0.880041063635361 2 Q8TB37 1 +Ribosomal protein S18 [IPR001648] 0.5484824066612924 0.212238515598865 0.8319209600203483 1.0 0.8805457894557827 2 Q9NVS2 1 +Clathrin adaptor, mu subunit [IPR001392] 0.5338527673293838 0.2092828887825556 0.8342274087881723 1.0 0.8826563407590212 3 Q9BXS5,Q96CW1 2 +Small GTPase Rho [IPR003578] 0.3948924731182723 0.2021974597516911 0.8397623589424368 1.0 0.8855276834686017 5 Q8IXI2,P63000,P84095,P60953 4 +SCAMP [IPR007273] 0.5281736722337755 0.1986507108743518 0.842535982508622 1.0 0.887119958019543 3 O15127 1 +Exocyst complex component EXOC6/Sec15 [IPR007225] 0.540424388933657 0.1975305941130606 0.8434123424108331 1.0 0.887119958019543 2 Q9Y2D4 1 +Lon protease, bacterial/eukaryotic-type [IPR004815] 0.5401557883427216 0.1970549451724033 0.8437845406012432 1.0 0.887119958019543 2 P36776 1 +Lon protease [IPR027065] 0.5401557883427216 0.1970549451724033 0.8437845406012432 1.0 0.887119958019543 2 P36776 1 +Heterogeneous nuclear ribonucleoprotein C [IPR017347] 0.5372011818425844 0.1918850118553001 0.8478322780885863 1.0 0.889389597326497 2 P07910 1 +Ras GTPase GNL1-like [IPR043358] 0.5366639806607594 0.1909572717369712 0.8485590692930394 1.0 0.8897625085843741 2 P36915 1 +Translation initiation factor IF- 2 [IPR015760] 0.5310233682513993 0.1814432040179253 0.856019709715784 1.0 0.8949872982779754 2 P46199 1 +Alanine-tRNA ligase, class IIc [IPR002318] 0.5280687617512749 0.1766248892760859 0.8598030426296801 1.0 0.8979458763138064 2 Q5JTZ9 1 +Alanine-tRNA ligase, eukaryota/bacteria [IPR023033] 0.5280687617512749 0.1766248892760859 0.8598030426296801 1.0 0.8979458763138064 2 Q5JTZ9 1 +Serpin family [IPR000215] 0.5118216012896196 0.170145617457151 0.8648956189617467 1.0 0.9025970164635888 3 P50454,P30740 2 +PDK/BCKDK protein kinase [IPR039028] 0.5099408919935428 0.1670685346563512 0.8673161237208702 1.0 0.9047887922863584 3 Q15120,O14874 2 +Oxysterol-binding protein [IPR000648] 0.359651445991032 0.1647770986164277 0.8691194302795286 1.0 0.9063353231966292 8 Q9BXW6 1 +H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415] 0.5079237174321652 0.1467669193124365 0.8833159964395918 1.0 0.9176721525541224 2 Q9NX24 1 +Histone deacetylase family [IPR000286] 0.5073865162503334 0.1460412512113769 0.8838888237521298 1.0 0.9176721525541224 2 Q13547 1 +Histone deacetylase [IPR003084] 0.5073865162503334 0.1460412512113769 0.8838888237521298 1.0 0.9176721525541224 2 Q13547 1 +Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515] 0.4966424926134737 0.1322790181263314 0.8947636026390644 1.0 0.9269186569326576 2 Q13310 1 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.4958366908407211 0.1313038530858197 0.8955349438609244 1.0 0.9270378220619684 2 O60884 1 +U3 snoRNP protein/Ribosome production factor 1 [IPR044281] 0.4896588772495137 0.1240867740889748 0.9012465699705672 1.0 0.931925900500312 2 Q9H9Y2 1 +Vacuolar protein sorting-associated protein 4 [IPR031255] 0.4891216760676804 0.1234806771447236 0.901726474589791 1.0 0.931986955731974 2 O75351 1 +Purine 5'-nucleotidase [IPR016695] 0.4888530754767545 0.123178905881137 0.90196542901636 1.0 0.931986955731974 2 P49902 1 +Pyrroline-5-carboxylate reductase [IPR000304] 0.4832124630674049 0.1170367070222447 0.9068309653550456 1.0 0.9356455358393002 2 Q96C36 1 +Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699] 0.4807950577491138 0.1145169738517531 0.9088279917250546 1.0 0.9373636643385468 2 Q9NQT5 1 +Peptidyl-tRNA hydrolase, PTH2 [IPR002833] 0.4738114423851722 0.1076088767512811 0.9143059552546612 1.0 0.9419818831489488 2 Q9Y3E5 1 +Calponin/LIMCH1 [IPR001997] 0.467633628793985 0.1019458388391624 0.918799665340229 1.0 0.9462665164368016 2 Q15417 1 +Protein-tyrosine phosphatase-like, PTPLA [IPR007482] 0.4638732205210742 0.0986985273709526 0.9213776381453372 1.0 0.9485757389798022 2 Q6Y1H2 1 +GDP dissociation inhibitor [IPR018203] 0.4578183772165409 0.0980344753441987 0.9219049178437712 1.0 0.94877282073175 3 P50395,P24386 2 +Phosphoinositide phospholipase C family [IPR001192] 0.4582326081117376 0.0941025166633922 0.9250277212466356 1.0 0.950947348079238 2 P16885 1 +Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279] 0.4582326081117376 0.0941025166633922 0.9250277212466356 1.0 0.950947348079238 2 P16885 1 +Tumour protein D52 [IPR007327] 0.4568896051571284 0.0930557879394577 0.925859241081022 1.0 0.9514559316310977 2 P55327 1 +Dynein light chain, type 1/2 [IPR001372] 0.4512489927477829 0.088853822111738 0.92919808294478 1.0 0.9541928696179582 2 P63167 1 +Paraneoplastic encephalomyelitis antigen [IPR002343] 0.4445339779747502 0.0842478502135332 0.9328593744177944 1.0 0.9569091259006062 2 Q15717 1 +Translin family [IPR002848] 0.4286865431103887 0.07496756061599 0.9402405221159296 1.0 0.962527339923451 2 Q99598 1 +Mitochondrial Rho GTPase [IPR021181] 0.394574268063392 0.0613890038530319 0.9510494094976488 1.0 0.9699330620328008 2 Q8IXI2 1 +Sirtuin family [IPR003000] 0.3679828095621854 0.0553684348569279 0.9558449425821962 1.0 0.9735738572738428 2 Q8IXJ6 1 +Septin [IPR016491] 0.3997850617947254 0.0543280602535536 0.956673793711276 1.0 0.9737390221296311 3 Q15019,Q9UHD8 2 +Translation initiation factor IF2/IF5 [IPR045196] 0.3421971528337348 0.052067236340335 0.9584751191527734 1.0 0.9739900041750305 2 P55010 1 +THRAP3/BCLAF1 family [IPR029199] 0.33279613215149 0.0512968494504872 0.9590889785756238 1.0 0.9742633457303622 2 Q9NYF8 1 +NudC family [IPR037898] 0.3323481998925204 0.0339467064843996 0.972919648243432 1.0 0.9872478470860974 3 Q8IVD9,Q8WVJ2 2 +KH domain-containing BBP-like [IPR045071] 0.294759858807132 0.0324551802834517 0.9741090581354928 1.0 0.98794117665501 4 Q07666 1 +DNA mismatch repair MutS family [IPR045076] 0.3036002149381971 0.0308395320380509 0.975397513395033 1.0 0.9881332832678098 3 P20585,P52701 2 +Chaperone DnaJ [IPR012724] 0.3006448146157836 0.0306281094837772 0.9755661245354504 1.0 0.9881332832678098 3 O60884,P31689 2 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6ed9bdb1aec34eb7a86a3e78543268b7914eb722 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "-alpha-acetyltransferase 35, NatC auxiliary subunit [IPR007244]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1,4-alpha-glucan-branching enzyme [IPR037439]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [IPR028381]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "16S/18S rRNA aminocarboxypropyltransferase Tsr3 [IPR022968]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 [IPR039210]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S18b, mitochondrial [IPR040054]", "28S ribosomal protein S24, mitochondrial [IPR026146]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3'5'-cyclic nucleotide phosphodiesterase [IPR023088]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-keto-steroid reductase [IPR042829]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease 1 [IPR016494]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "50S ribosomal protein uL4 [IPR013005]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchor protein 9/Pericentrin [IPR028745]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABI family [IPR028457]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 10 [IPR042951]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6 [IPR041839]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 6-interacting protein 6 [IPR029383]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AF4/FMR2 family [IPR007797]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AMP deaminase 2 [IPR029749]", "AMP deaminase [IPR006329]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1 complex subunit sigma [IPR044733]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "AT-rich interactive domain-containing protein 4B [IPR028853]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit ATP5MJ, mitochondrial [IPR012574]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP synthase-coupling factor 6, mitochondrial [IPR008387]", "ATP-binding cassette sub-family C member 4 [IPR030240]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase ARIP4-like [IPR044574]", "ATPase PAAT-like [IPR028043]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Abl interactor 1 [IPR028456]", "Abr/Bcr [IPR037769]", "Acetyl-coenzyme A transporter 1-like [IPR024371]", "Acid ceramidase-like [IPR016699]", "Acid sphingomyelinase-like phosphodiesterase, predicted [IPR017064]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-histidine N-methyltransferase SETD3 [IPR025785]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 2/3 complex subunit 5 [IPR006789]", "Actin-related protein 3 [IPR015623]", "Activating signal cointegrator 1-like [IPR039128]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active zone protein ELKS [IPR019323]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A diphosphatase NUDT19 [IPR039121]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenomatous polyposis coli (APC) family [IPR026818]", "Adenomatous polyposis coli [IPR026836]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase [IPR030672]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "Adenylyltransferase and sulfurtransferase MOCS3/Uba4 [IPR028885]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-1,2-mannosyltransferase ALG9-like [IPR039484]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-catulin 1 [IPR030045]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase ALAT1/2-like [IPR045088]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid beta precursor protein binding family B member 1/2/3 [IPR039576]", "Amyloid-beta precursor protein [IPR028866]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 4 [IPR024789]", "Anaphase-promoting complex subunit 4, metazoa [IPR017169]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Anion exchange protein 2 [IPR002978]", "Anion exchange protein [IPR001717]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Ankyrin repeat and SAM domain-containing protein 1A [IPR033637]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A3 [IPR002390]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-10 [IPR031291]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Antigen peptide transporter 2 [IPR005293]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAK [IPR026308]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Apyrase [IPR009283]", "ArfGAP ACAP1/2/3-like [IPR045258]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arv1 protein [IPR007290]", "Arylacetamide deacetylase [IPR017157]", "Arylesterase [IPR002640]", "Ashwin [IPR024887]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Asparaginyl endopeptidase [IPR043577]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase B [IPR028772]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 11 [IPR040040]", "Autophagy-related protein 9 [IPR007241]", "B-cell lymphoma/leukemia 10/E10 [IPR033238]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BEN domain-containing protein 3 [IPR033583]", "BET1-like protein [IPR039897]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRCA1-associated [IPR031099]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "BTB-kelch protein [IPR017096]", "BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1/2/3 [IPR045068]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-galactosyltransferase [IPR003859]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-2-syntrophin [IPR028550]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-adducin [IPR027773]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bicaudal-D protein [IPR018477]", "Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [IPR013109]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "Bis(5'-adenosyl)-triphosphatase ENPP4 [IPR029879]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bromodomain adjacent to zinc finger domain protein 2A [IPR028940]", "Bud22/Serum response factor-binding protein 1 [IPR037393]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 2-like [IPR039934]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CASP8-associated protein 2 [IPR039674]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 10 [IPR039740]", "CCR4-NOT transcription complex subunit 11 [IPR019312]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD34/Podocalyxin [IPR013836]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDC50/LEM3 family [IPR005045]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK2-associated and cullin domain-containing protein 1 [IPR042652]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-alcohol phosphatidyltransferase class-II family [IPR016270]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CGG triplet repeat-binding protein 1 [IPR033375]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome complex subunit 7B [IPR027530]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calmodulin-regulated spectrin-associated protein [IPR032940]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calsyntenin [IPR026914]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Carboxymethylenebutenolidase homolog [IPR042946]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-8 [IPR033170]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cation/H+ exchanger, CPA1 family [IPR018422]", "Cationic amino acid transport permease [IPR004755]", "Ccdc97-like [IPR018613]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle control protein 50A [IPR030351]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein Cdc6/18 [IPR016314]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Cellular repressor of E1A-stimulated genes (CREG) [IPR014631]", "Centrin 2 [IPR037629]", "Centromere protein Cenp-F [IPR043513]", "Centromere protein I [IPR012485]", "Centromere protein U [IPR025214]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 290kDa [IPR026201]", "Centrosomal protein of 44kDa [IPR033603]", "Centrosomal protein of 55kDa [IPR038926]", "Ceramide glucosyltransferase [IPR025993]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Ceroid-lipofuscinosis neuronal protein 6 [IPR029255]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Choline/ethanolamine phosphotransferase [IPR014472]", "Chondroitin N-acetylgalactosaminyltransferase [IPR008428]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin complexes subunit BAP18 [IPR037931]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homolog 2 [IPR042796]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 5 [IPR028727]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cilia- and flagella-associated protein 298 [IPR021298]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Citron Rho-interacting kinase [IPR017405]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Cochlin [IPR030743]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil and C2 domain-containing protein 1 [IPR039725]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 127 [IPR034607]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 137 [IPR026680]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Condensin-2 complex subunit G2 [IPR024741]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Conserved oligomeric Golgi complex subunit 8 [IPR007255]", "Conserved oligomeric Golgi complex subunit 8, Metazoal and Viridiplantae [IPR016632]", "Conserved oligomeric Golgi complex, subunit 3 [IPR007265]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin 7 [IPR027331]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclin-dependent kinase 7 [IPR037770]", "Cyclin/Cyclin-like subunit Ssn8 [IPR043198]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine oxygenase/2-aminoethanethiol dioxygenase [IPR012864]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoplasmic tRNA 2-thiolation protein 2 [IPR019407]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 16 [IPR028216]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutL/Mlh/Pms [IPR038973]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase delta subunit 3 [IPR019038]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair protein XPF [IPR006167]", "DNA repair protein XRCC4 [IPR010585]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication ATP-dependent helicase/nuclease Dna2 [IPR026851]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IA [IPR000380]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed DNA-polymerase, family A, mitochondria [IPR002297]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase III subunit Rpc5 [IPR006886]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "DUF5568 family [IPR040419]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deltex family [IPR039398]", "Deoxycytidylate deaminase [IPR016473]", "Deoxycytidylate deaminase-related [IPR015517]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxyribonuclease II [IPR004947]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 4 [IPR030612]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone kinase [IPR012734]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dimethylarginine dimethylaminohydrolase [IPR033199]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphosphomevalonate decarboxylase [IPR029765]", "Diphosphomevalonate/phosphomevalonate decarboxylase [IPR005935]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Dishevelled family [IPR008339]", "Dishevelled-2 [IPR008341]", "Dishevelled-related protein [IPR015506]", "Disks large 1-like [IPR016313]", "Divalent ion tolerance protein, CutA [IPR004323]", "Divergent protein kinase domain 2A/B [IPR020519]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dymeclin [IPR019142]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1 [IPR027741]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-binding protein [IPR035469]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase CBX4 [IPR043531]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 SUMO-protein ligase PIAS1 [IPR027227]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase HECTD3 [IPR042469]", "E3 ubiquitin-protein ligase MGRN1/RNF157-like [IPR045194]", "E3 ubiquitin-protein ligase Praja-2 [IPR030639]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RNF14 [IPR031128]", "E3 ubiquitin-protein ligase RNF213 [IPR031248]", "E3 ubiquitin-protein ligase RNF31-like [IPR026254]", "E3 ubiquitin-protein ligase UBR7 [IPR040204]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand calcium-binding domain-containing protein 14 [IPR042352]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "Ecd family [IPR010770]", "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [IPR029890]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongator complex protein 4 [IPR008728]", "Elongin B [IPR039049]", "Emerin [IPR035004]", "Emopamil-binding protein [IPR007905]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endothelial protein C receptor [IPR015669]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Ephrin receptor type-A /type-B [IPR016257]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Est1/Ebs1-like [IPR045153]", "Esterase-like [IPR000801]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Eukaryotic translation initiation factor 4E binding protein [IPR018862]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exostosin-2 [IPR027673]", "Exostosin-like [IPR004263]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "F-box only protein 38 [IPR042354]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM105 [IPR023235]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM91 [IPR039199]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FLYWCH-type zinc finger-containing protein 1/2 [IPR040312]", "FMP27 [IPR045167]", "FUN14 [IPR007014]", "Fanconi anaemia group A protein [IPR003516]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 2 [IPR030305]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "FeS cluster insertion protein [IPR016092]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferritin [IPR001519]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Focadhesin [IPR021392]", "Focadhesin/RST1 [IPR045163]", "Forkhead box protein C1 [IPR033067]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Formin-binding protein 1 [IPR028532]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein alpha subunit, group Q [IPR000654]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "G2 and S phase-expressed protein 1 [IPR026659]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase 2-like [IPR045130]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GOLM1/CASC4 family [IPR026139]", "GOSR2/Membrin/Bos1 [IPR027027]", "GPCR, family 2, ADGRE2/ADGRE5 [IPR003056]", "GPCR, family 2, secretin-like [IPR000832]", "GPI ethanolamine phosphate transferase 2 [IPR039527]", "GPI ethanolamine phosphate transferase 3 [IPR039524]", "GPI mannosyltransferase [IPR005599]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI transamidase subunit PIG-U [IPR009600]", "GPI-anchor transamidase [IPR028361]", "GPN-loop GTPase 1 [IPR030230]", "GPN-loop GTPase [IPR004130]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GRIP1-associated protein 1 [IPR026204]", "GTP cyclohydrolase 1 type 2/Nif3 [IPR002678]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "Galactokinase [IPR000705]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-glutamyltranspeptidase [IPR000101]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gem-associated protein 4 [IPR033265]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine 6-phosphate N-acetyltransferase [IPR039143]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl hydrolase family 99 [IPR026071]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 43 [IPR005027]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi membrane protein 1 [IPR026143]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Groucho/transducin-like enhancer [IPR009146]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor Ect2 [IPR026817]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "Guided entry of tail-anchored proteins factor CAMLG [IPR016719]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "H/ACA ribonucleoprotein complex, subunit Nop10 [IPR007264]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like [IPR011949]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HEXIM [IPR024872]", "HMG domain-containing protein 4 [IPR042477]", "HMG-CoA lyase [IPR043594]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 12A [IPR026685]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase SMUBP-2/Hcs1-like [IPR004483]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histidine-tRNA ligase [IPR015807]", "Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit [IPR004516]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone PARylation factor 1 [IPR019361]", "Histone acetyltransferase KAT5/Tip60 [IPR037995]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex subunit SAP30/SAP30-like [IPR024145]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone transcription regulator 3/CABIN1 [IPR033053]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1 [IPR038035]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase SETD1A [IPR037841]", "Histone-lysine N-methyltransferase SETD2, animal [IPR042294]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Set1-like [IPR044570]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Huntingtin-interacting protein 1 [IPR030554]", "Huntingtin-interacting protein 1-related protein [IPR030555]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "IQ calmodulin-binding motif-containing protein 1 [IPR028765]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Immunity-related GTPase family Q protein [IPR040070]", "Impact family [IPR023582]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inactive ubiquitin thioesterase OTULINL [IPR023236]", "Inclusion body clearance protein Iml2/Tetratricopeptide repeat protein 39 [IPR019412]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Innexin [IPR000990]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 1,4,5-trisphosphate receptor-interacting protein [IPR024797]", "Inositol 1,4,5-trisphosphate receptor-interacting protein family [IPR026250]", "Inositol 3,4-bisphosphate 4-phosphatase [IPR039034]", "Inositol monophosphatase-like [IPR000760]", "Inositol-tetrakisphosphate 1-kinase [IPR008656]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 10 [IPR026164]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 5 [IPR040316]", "Integrator complex subunit 7 [IPR033060]", "Integrator complex subunit 8 [IPR038751]", "Integrator complex subunit 9 [IPR027074]", "Integrin alpha chain [IPR000413]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon gamma receptor alpha subunit [IPR008355]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intersectin-2 [IPR027029]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isoamyl acetate-hydrolyzing esterase Iah1-like [IPR045136]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "Junctional protein associated with coronary artery disease [IPR028221]", "K/Cl co-transporter 4 [IPR030354]", "K/Cl co-transporter [IPR000076]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Katanin p60 subunit A1 [IPR028596]", "Kelch-like ECH-associated protein 1 [IPR030563]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-associated protein 3 [IPR008658]", "Kinesin-like protein KIF15/KIN-12E [IPR044986]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore Mis14/Nsl1 [IPR013950]", "Kinetochore protein Ndc80 [IPR005550]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LAR-interacting protein, Liprin [IPR029515]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LIM domain only protein 7 [IPR029978]", "LIM domain-binding protein 1 [IPR030167]", "LIM-domain binding protein/SEUSS [IPR029005]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "Las1 [IPR007174]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Lethal(3)malignant brain tumour-like protein 2 [IPR038038]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat-containing 41 [IPR026137]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte elastase inhibitor (serpin B1) [IPR015557]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Liprin-alpha-1 [IPR030438]", "Lon protease [IPR027065]", "Lon protease homologue 2, peroxisomal [IPR027501]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lupus La protein [IPR002344]", "LysM and putative peptidoglycan-binding domain-containing protein 1-4 [IPR045030]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "MAX gene-associated protein [IPR037935]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "MICAL-like protein [IPR028563]", "MICAL3 [IPR029941]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MKRN-like [IPR045072]", "MOB kinase activator family [IPR005301]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "Macrophage migration inhibitory factor [IPR001398]", "Mad1/Cdc20-bound-Mad2 binding protein [IPR009511]", "Magnesium transporter protein 1 [IPR006844]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannose-P-dolichol utilization defect 1 protein [IPR016817]", "Med25/PTOV1 [IPR045105]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med21 [IPR021384]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med27 [IPR021627]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D1 [IPR030083]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Menin [IPR007747]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylmalonic aciduria and homocystinuria type D protein [IPR019362]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribulose-1-phosphate dehydratase [IPR017714]", "Methylthioribulose-1-phosphate dehydratase, eukaryotes [IPR027514]", "Methylthiotransferase [IPR005839]", "Methyltransferase Ppm1/Ppm2/Tcmp [IPR007213]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate kinase [IPR006205]", "Mevalonate/galactokinase [IPR006206]", "Mff/Tango-11 [IPR008518]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondria fission 1 protein [IPR016543]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial fission regulator 1 [IPR007972]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial outer membrane transport complex protein, metaxin [IPR017410]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase kinase kinase 7 [IPR017421]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdenum cofactor biosynthesis C [IPR023045]", "Molybdenum cofactor biosynthesis protein A [IPR013483]", "Molybdenum cofactor sulfurase [IPR028886]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myocardin-like [IPR043451]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 14 [IPR039802]", "Myotubularin-related protein 4 [IPR030590]", "Myotubularin-related protein 6 [IPR030581]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 [IPR033202]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylgalactosamine-6-sulfatase [IPR035626]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetylglucosaminyltransferase II [IPR007754]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NF-kappa-B inhibitor-like protein 1 [IPR038753]", "NF-kappa-B/Dorsal [IPR000451]", "NIF3-like protein 1, animal [IPR017222]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Na+/H+ exchanger [IPR004709]", "Na+/H+ exchanger, isoform 6/7/9 [IPR002090]", "Nck-associated protein 1 [IPR019137]", "Nectin-2 [IPR033318]", "Negative elongation factor E [IPR033102]", "Neogenin [IPR033024]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neural Wiskott-Aldrich syndrome protein [IPR030214]", "Neural cell adhesion [IPR009138]", "Neural cell adhesion molecule 1 [IPR033019]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neurogenic locus Notch 2 [IPR022336]", "Neuropilin [IPR014648]", "Neuropilin-1 [IPR027146]", "Neuroplastin [IPR027112]", "Neutral amino acid SLC6 transporter [IPR002438]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Non-specific endonuclease [IPR040255]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Not2/Not3/Not5 [IPR040168]", "Notch [IPR008297]", "Nuclear MIS12/MIND complex subunit PMF1/Nnf1 [IPR007128]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear factor related to kappa-B-binding protein [IPR024867]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear hormone receptor [IPR001723]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear receptor coactivator 4 [IPR039947]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar and spindle-associated protein 1 [IPR026756]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside phosphatase GDA1/CD39 [IPR000407]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC domain-containing protein 3 [IPR027761]", "NudC family [IPR037898]", "Nurim-like [IPR033580]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "OPI10 family [IPR031318]", "ORC ubiquitin ligase 1 [IPR039209]", "Occludin [IPR002958]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 1 [IPR020793]", "Origin recognition complex, subunit 2 [IPR007220]", "Origin recognition complex, subunit 3 [IPR020795]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Osteopetrosis-associated transmembrane protein 1 precursor [IPR019172]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IB [IPR027256]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "P-type ATPase, subfamily IV [IPR006539]", "PA2G4 family [IPR004545]", "PAN2-PAN3 deadenylation complex catalytic subunit PAN2 [IPR030843]", "PAT complex subunit CCDC47 [IPR012879]", "PCNA-associated factor [IPR040444]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PDZ domain-containing protein 8 [IPR039275]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PSME3-interacting protein [IPR039845]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Palmitoyltransferase ZDHHC13 [IPR030290]", "Pannexin [IPR039099]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic antigen Ma [IPR026523]", "Paraneoplastic antigen Ma1 [IPR026528]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Pat1-like [IPR039900]", "Paxillin [IPR001904]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C50, separase [IPR005314]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M2, peptidyl-dipeptidase A [IPR001548]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1A, Tysnd1 [IPR017345]", "Peptidase S1C [IPR001940]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Peptidylglycine alpha-hydroxylating monooxygenase/peptidyl-hydroxyglycine alpha-amidating lyase [IPR000720]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal/glyoxysomal leader peptide-processing protease [IPR039245]", "Peroxisome membrane protein, Pex16 [IPR013919]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phenylalanyl-tRNA synthetase, class IIc, mitochondrial [IPR004530]", "Phosducin-like [IPR045037]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphatidylserine lipase ABHD16A [IPR026604]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phospholipid-transporting ATPase IG [IPR030363]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylase kinase alpha/beta subunit [IPR008734]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotriesterase [IPR001559]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Podocalyxin [IPR017403]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polycomb protein EED [IPR037352]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SLU7 [IPR039974]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Pre-rRNA-processing protein TSR2 [IPR019398]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prefoldin, subunit 4 [IPR016661]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable E3 ubiquitin-protein ligase makorin-2 [IPR026293]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Progesterone-induced-blocking factor 1 [IPR026205]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Proline/serine-rich coiled-coil protein 1/G2 and S phase-expressed protein 1 [IPR026657]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein TESPA1-like [IPR043444]", "Protein AATF/Bfr2 [IPR039223]", "Protein BANP [IPR042343]", "Protein BRAWNIN [IPR027858]", "Protein C10 [IPR026317]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein FAM234 [IPR045232]", "Protein FAM3C [IPR039219]", "Protein FAM8A1 [IPR039871]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein ITPRID2 [IPR026648]", "Protein LCHN/Anr2 [IPR018626]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein MMS22-like [IPR042320]", "Protein Mon2-like [IPR026829]", "Protein NDRG3 [IPR030692]", "Protein Njmu-R1 [IPR028280]", "Protein OS-9-like [IPR045149]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SMG8 [IPR028802]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein Spindly, chordates [IPR028593]", "Protein TFG [IPR033512]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein diaphanous homologue 2 [IPR027644]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C, alpha/beta/gamma types [IPR014375]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kinase Mps1 family [IPR027084]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF1356, TMEM106 [IPR009790]", "Protein of unknown function DUF1387 [IPR009816]", "Protein of unknown function DUF167 [IPR003746]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF3827 [IPR024606]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF719 [IPR007998]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein strawberry notch [IPR026741]", "Protein suppressor of sable-like [IPR045124]", "Protein translocase SEC61 complex, gamma subunit [IPR008158]", "Protein translocase complex, SecE/Sec61-gamma subunit [IPR001901]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein unc-119 homologue A-like [IPR032977]", "Protein virilizer [IPR026736]", "Protein wntless [IPR009551]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Purine-rich element-binding protein beta [IPR030499]", "Putative RNA methyltransferase [IPR003750]", "Putative peptidyl-tRNA hydrolase PTRHD1 [IPR042237]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate homeostasis protein [IPR011078]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAB11-binding protein RELCH [IPR040362]", "RAD3/XPD family [IPR001945]", "RAD51-associated protein 1 [IPR026632]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cap guanine-N2 methyltransferase [IPR019012]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II elongation factor ELL [IPR031184]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "ROK family [IPR000600]", "RPA-related protein RADX [IPR040893]", "RSBN1/Dpy-21 [IPR026306]", "RZZ complex, subunit Zw10 [IPR009361]", "RZZ complex, subunit Zwilch [IPR018630]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab protein geranylgeranyltransferase component A [IPR001738]", "Rab11-family interacting protein class I [IPR037789]", "Rab12 [IPR041830]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab3 [IPR037872]", "Rab33A/B [IPR041822]", "Rab35 [IPR041815]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rabaptin [IPR003914]", "Rabaptin-5 [IPR029880]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "Ral GTPase-activating protein subunit beta [IPR039930]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein [IPR039360]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Rab29/Rab38/Rab32 [IPR030697]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulon-4-interacting protein 1 [IPR037397]", "Reticulophagy receptor 1/3 [IPR043384]", "Reticulophagy regulator 3 [IPR033361]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho GDP/GTP exchange factor Kalirin/TRIO [IPR028570]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2 subunit B [IPR040456]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA small subunit methyltransferase H [IPR002903]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein 7 [IPR040446]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L16 [IPR000114]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e [IPR023438]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27/L41, mitochondrial [IPR019189]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein Rsm22-like [IPR015324]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S26e [IPR000892]", "Ribosomal protein S27/S33, mitochondrial [IPR013219]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Root UVB sensitive family [IPR006968]", "Roundabout homologue 1 [IPR032986]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAGA-associated factor 29 [IPR037802]", "SAP30-binding protein [IPR012479]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SCAR/WAVE family [IPR028288]", "SERRATE/Ars2 [IPR039727]", "SH3 and PX domain-containing protein 2B [IPR030512]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SPRY domain-containing protein 7 [IPR035766]", "STEEP-like [IPR029704]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BAF60B [IPR030090]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sdc1/DPY30 [IPR037856]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenium-binding protein [IPR008826]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 2-like [IPR034893]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase ATM/Tel1 [IPR015519]", "Serine/threonine-protein kinase Atg1-like [IPR045269]", "Serine/threonine-protein kinase MRCK beta [IPR033232]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase SMG1 [IPR031559]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shootin-1 [IPR024849]", "Short transient receptor potential channel 4-associated protein [IPR022162]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sialate O-acetylesterase [IPR039329]", "Sialidase family [IPR026856]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sirtuin, class I [IPR017328]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sla2 family [IPR030224]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium/solute symporter [IPR001734]", "Sodium:dicarboxylate symporter [IPR001991]", "Sodium:neurotransmitter symporter [IPR000175]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 12 member 9 [IPR030345]", "Solute carrier family 25 member 44 [IPR042164]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-25 [IPR034905]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-4 [IPR034783]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermatogenesis-defective protein 39 [IPR040057]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterile alpha and TIR motif-containing protein 1 [IPR039184]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol regulatory element-binding protein cleavage-activating protein [IPR030225]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Stromal interaction molecule 1 [IPR030463]", "Stromal interaction molecule [IPR037608]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of hairless-like [IPR040159]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptic vesicle protein SV2 [IPR022308]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syndetin [IPR040047]", "Syntaxin [IPR045242]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "Syntrophin [IPR015482]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA element modulatory factor 1 DNA binding [IPR022092]", "TATA-binding protein-associated factor Mot1 [IPR044972]", "TB2/DP1/HVA22-related protein [IPR004345]", "TE2IP/Rap1 [IPR039595]", "TFIIH subunit Tfb1/GTF2H1 [IPR027079]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TIP41-like protein [IPR007303]", "TMEM115/Pdh1/Rbl19 [IPR013861]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM206 protein [IPR029366]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TNF receptor-associated factor 2 [IPR027133]", "TNF receptor-associated factor TRAF [IPR043211]", "TNF receptor-associated factor TRAF, metazoa [IPR012227]", "TOX high mobility group box family member 4 [IPR037985]", "TPMT family [IPR008854]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP III complex, Trs85 [IPR024420]", "TREX component Tex1/THOC3 [IPR040132]", "TRIC channel [IPR007866]", "Tankyrase 1-binding protein-like [IPR040006]", "Target of Myb protein 1 [IPR014645]", "Target of Myb1-like 2 [IPR027429]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Tectonic [IPR040354]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Teneurin-3/4 [IPR027691]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 21A/21B [IPR040364]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "The WD repeat Cdc20/Fizzy family [IPR033010]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thiopurine S-methyltransferase [IPR025835]", "Thioredoxin domain-containing protein 16 [IPR040090]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor RelA (p65) [IPR030495]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription factor, T-box [IPR001699]", "Transcription factor, enhancer of yellow 2 [IPR018783]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription initiation factor TAFII31 [IPR003162]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor NocA-like [IPR022129]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery associated TMA7 [IPR015157]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Translocon-associated protein subunit gamma [IPR009779]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 11 [IPR026120]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein 98 [IPR029668]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transmembrane protein TqsA-like [IPR002549]", "Transposase, L1 [IPR004244]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Trimethyllysine dioxygenase [IPR012776]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "TspO/MBR-related protein [IPR004307]", "Tti2 family [IPR018870]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin epsilon and delta complex protein 1 [IPR043535]", "Tubulin polyglutamylase TTLL4 [IPR027748]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine protein kinase, EGF/ERB/XmrK receptor [IPR016245]", "Tyrosine-protein kinase, insulin-like receptor [IPR016246]", "Tyrosine-protein kinase, non-receptor Jak/Tyk2 [IPR016251]", "Tyrosine-protein kinase, non-receptor Jak1 [IPR020776]", "Tyrosine-protein phosphatase non-receptor type 13 [IPR012153]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm1/8 [IPR044642]", "U6 snRNA-associated Sm-like protein Lsm3 [IPR040002]", "UAA transporter [IPR013657]", "UAP56-interacting factor [IPR009782]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing [IPR020004]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 4-epimerase [IPR005886]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-glucuronic acid decarboxylase [IPR044516]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "UbiA prenyltransferase domain containing protein 1 [IPR026046]", "UbiA prenyltransferase family [IPR000537]", "UbiE/COQ5 methyltransferase [IPR004033]", "Ubiquilin-1/2 [IPR028430]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin domain-containing protein UBFD1 [IPR039120]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin thioesterase otulin [IPR023237]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-associated protein 1 [IPR038870]", "Ubiquitin-fold modifier-conjugating enzyme 1 [IPR014806]", "Ubiquitin-like modifier Hub1/Ubl5 [IPR039732]", "Ubiquitin-like modifier-activating enzyme Atg7 [IPR006285]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Ubiquitously expressed transcript protein UXT [IPR003994]", "Uncharacterised conserved protein UCP013899, metal binding [IPR016617]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family, TMEM59 [IPR022065]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Uracil-DNA glycosylase family 1 [IPR002043]", "Ureohydrolase [IPR006035]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar fusion protein Ccz1 [IPR013176]", "Vacuolar import/degradation protein Vid24 [IPR018618]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated Vps28 [IPR007143]", "Vacuolar protein sorting-associated protein 11 [IPR016528]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Vacuole morphology and inheritance protein 14 [IPR026825]", "Valine-tRNA ligase [IPR002303]", "Vam6/VPS39/TRAP1 family [IPR032914]", "Vang-like protein [IPR009539]", "Very low-density lipoprotein receptor [IPR032931]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle transport protein, Use1 [IPR019150]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "Vps72/YL1 family [IPR008895]", "WASH complex subunit 3 [IPR019309]", "WASH complex, subunit strumpellin [IPR019393]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat-containing protein 11 [IPR039694]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR48/Bun107 [IPR021772]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XAP5 protein [IPR007005]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger CCHC domain-containing protein 9 [IPR042246]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger protein 131 [IPR027758]", "Zinc finger protein 277 [IPR040048]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc finger protein 830-like [IPR040050]", "Zinc transporter Msc2-like [IPR045316]", "Zinc/iron permease [IPR003689]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA export factor GLE1-like [IPR012476]", "mRNA export factor Gle2/RAE1 [IPR037631]", "mRNA-decapping enzyme subunit 1 [IPR010334]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (guanine(37)-N(1))-methyltransferase, eukaryotic [IPR025792]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA (uracil-5-)-methyltransferase, metazoa [IPR025823]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-specific 2-thiouridylase [IPR004506]", "tRNAHis guanylyltransferase Thg1 [IPR007537]"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABHD12", "ABHD16A", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACADM", "ACAP2", "ACAT1", "ACAT2", "ACBD5", "ACE2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADCY3", "ADD1", "ADD2", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFF4", "AFG3L2", "AGAP3", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG9", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANKLE2", "ANKS1A", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEX1", "API5", "APIP", "APLP2", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFIP1", "ARFIP2", "ARG2", "ARHGDIA", "ARID1A", "ARID3B", "ARID4B", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL6IP6", "ARL8B", "ARMC1", "ARMC6", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATM", "ATP11C", "ATP13A1", "ATP13A2", "ATP13A3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATXN2L", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG4", "BAG5", "BAIAP2", "BAK1", "BANF1", "BANP", "BAP18", "BASP1", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT1", "BCAT2", "BCCIP", "BCKDK", "BCL10", "BCL2L13", "BCLAF1", "BCR", "BEND3", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRIP1", "BRIX1", "BROX", "BSG", "BTAF1", "BTF3", "BUB1B", "BUD23", "BUD31", "BYSL", "C10orf88", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C15orf40", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C21orf59", "C2CD2", "C2CD5", "C2orf49", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf33", "CAB39", "CABIN1", "CACUL1", "CAD", "CALD1", "CALR", "CALU", "CAMLG", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASP8", "CASP8AP2", "CAST", "CBL", "CBR1", "CBX2", "CBX3", "CBX4", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC137", "CCDC138", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCDC97", "CCNB1", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC20", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK5RAP3", "CDK6", "CDK7", "CDKAL1", "CDS2", "CEBPZ", "CELF2", "CENPF", "CENPI", "CENPU", "CEP170", "CEP290", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD5", "CHD8", "CHERP", "CHM", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CIAPIN1", "CIP2A", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COCH", "COG3", "COG7", "COG8", "COIL", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CREG1", "CRNKL1", "CROT", "CRTAP", "CS", "CSGALNACT2", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC27", "CWF19L1", "CXorf56", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF16", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDX54", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHTKD1", "DHX29", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DMD", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNASE2", "DNM1", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EED", "EEF1A2", "EEF1E1", "EEF1G", "EFCAB14", "EFHD1", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4ENIF1", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENPP4", "ENTPD7", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAH", "FAM105A", "FAM114A2", "FAM120A", "FAM120B", "FAM162A", "FAM177A1", "FAM192A", "FAM213A", "FAM234B", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARS2", "FARSA", "FARSB", "FAU", "FBL", "FBXO38", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIS1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FN3KRP", "FNBP1", "FOCAD", "FOXC1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALE", "GALK1", "GALNS", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GGT7", "GHDC", "GHITM", "GID4", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GM2A", "GMFB", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRIPAP1", "GRPEL1", "GRSF1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDHD2", "HDHD3", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP2", "IGHMBP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS10", "INTS13", "INTS14", "INTS3", "INTS5", "INTS7", "INTS8", "INTS9", "IPO4", "IPO5", "IQCB1", "IRGQ", "IRS4", "ISCA2", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "JAGN1", "JAK1", "JCAD", "JPT2", "JUP", "KARS", "KAT5", "KATNA1", "KCTD10", "KDELR1", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KIAA0100", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA1549", "KIAA2013", "KIF14", "KIF15", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFAP3", "KIFBP", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "L3MBTL2", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDB1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMF2", "LMO7", "LNPEP", "LONP1", "LONP2", "LRPAP1", "LRPPRC", "LRRC41", "LRRC47", "LSG1", "LSM12", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYSMD3", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAD2L1BP", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP3K7", "MAP4", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED27", "MEN1", "MEPCE", "MESD", "METAP2", "METTL15", "METTL17", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGA", "MGAT2", "MGEA5", "MGRN1", "MGST2", "MGST3", "MICAL3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKL2", "MKRN2", "MLEC", "MMAB", "MMADHC", "MMGT1", "MMS19", "MMS22L", "MOB4", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MON2", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPST", "MPV17", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTFR1", "MTFR1L", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MTX3", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYO18A", "NAA15", "NAA25", "NAA35", "NAA40", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCLN", "NCOA4", "NCSTN", "NDC1", "NDC80", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF3", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NEO1", "NES", "NEU1", "NF1", "NF2", "NFKBIL1", "NFRKB", "NFS1", "NHP2", "NIF3L1", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NME3", "NME4", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRM", "NRP1", "NSA2", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT19", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUSAP1", "NUTF2", "NXF1", "OAT", "OCIAD1", "OCLN", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC1", "ORC2", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSTM1", "OTUB1", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAK2", "PAM", "PAN2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PBDC1", "PBRM1", "PC", "PCBD1", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDP1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PELO", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGS1", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4K2B", "PI4KA", "PI4KB", "PIAS1", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGO", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PJA2", "PKM", "PKMYT1", "PKP2", "PLA2G15", "PLBD2", "PLCG1", "PLCG2", "PLEC", "PLIN3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNA3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNMA1", "PNN", "PNO1", "PNP", "PNPT1", "PODXL", "POFUT1", "POFUT2", "POLA1", "POLD1", "POLD2", "POLD3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIE", "PPIH", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R12A", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKACB", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN23", "PTRH2", "PTRHD1", "PUF60", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB31", "RAB32", "RAB33B", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1CC1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM45", "RBM5", "RBM6", "RBM8A", "RBPJ", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF20", "RNF213", "RNF219", "RNF31", "RNF40", "RNMT", "RNPEP", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTFDC1", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARS", "SARS2", "SART1", "SBDS", "SBNO1", "SCAF1", "SCAMP2", "SCAMP3", "SCAMP4", "SCAP", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SCRN3", "SDAD1", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SELENOI", "SENP3", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHTN1", "SIAE", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A6", "SLFN11", "SLK", "SLTM", "SLU7", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMG1", "SMG6", "SMG8", "SMPD4", "SMPDL3A", "SMPDL3B", "SMU1", "SMYD3", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX25", "SNX27", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATS2L", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPOUT1", "SPR", "SPRYD7", "SPTBN1", "SPTBN2", "SQLE", "SRFBP1", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF2", "SRSF6", "SSB", "SSBP1", "SSFA2", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX12", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SV2A", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARS", "TARS2", "TARSL2", "TBCA", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCTN3", "TECR", "TEDC1", "TEFM", "TENM3", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFRC", "TGFBRAP1", "TGS1", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIPRL", "TJP1", "TK1", "TKFC", "TLE3", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM11", "TMEM115", "TMEM126B", "TMEM14C", "TMEM160", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM206", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", 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sha256:8901dd3d89306c62e0a6a7aa1bf8732ae0e3eebd1e737aa61a6349a29b8706d4 +size 137994 diff --git a/interpro_homologous_superfamily/consensus.joblib b/interpro_homologous_superfamily/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..9cf2500b0daf6f14899905ddfa07dcaee763bfa5 --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:21098187340f4f2c768b11072b2552a8453b7ed239c2e9ff52cf460b249eb16b +size 151590 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bd5ac1f4853cbc10b11691efff4f558a3a8f1863 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,20 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Immunoglobulin-like fold [IPR013783] 30 54 3.9522626841529065 7.741569015951022e-05 9.024271844660197 30.70631067961165 -0.0882371106398617 0.5574652875269992 4.075666983819175 5.992200349595445 1.1066442573771362 0.3307702752839019 7.388623737702107e-07 0.0240926187715494 0.0058728569982275 2.04133132272489e-06 1.2329150350718624e-07 +Immunoglobulin-like domain superfamily [IPR036179] 21 26 3.3588400659198303 0.000782703520896 4.480582524271845 12.427184466019416 0.4075261998509777 0.4433674298264088 2.6479725987944898 3.173316973839475 1.1756568118942026 0.3233613924696422 6.280250851536739e-05 0.433640456963297 0.303304644259416 0.0004506920536562 2.3620282017804656e-06 +Glycoside hydrolase superfamily [IPR017853] 13 20 3.2998933440341736 0.0009672157939459 7.094660194174757 15.565533980582524 0.5992585613623983 0.1928722204186086 2.565315823223627 1.245604487832095 1.9386029676344616 0.2695693578719223 5.90474262884942e-16 2.717687438751005e-13 2.494047808341458e-16 1.1698442022244783e-16 2.467477594082836e-15 +Six-bladed beta-propeller, TolB-like [IPR011042] 8 13 2.805311104546793 0.005026803560062 1.3446601941747574 5.393203883495145 0.4812306698455429 0.3983263887517446 1.462357994456035 1.8263849452238317 1.127948748997717 0.299664609287172 1.31519826470158e-07 0.0060718409625537 7.906884127520583e-08 1.0652118507020126e-06 9.317475755418402e-07 +Growth factor receptor cysteine-rich domain superfamily [IPR009030] 8 10 2.792571418271624 0.0052290922981086 1.2203856749311297 2.6942148760330578 -0.1665405502801967 0.33863481843602 1.1834128472166114 1.8370669604533123 1.6157864534436548 0.3193113842408702 9.081461175905364e-06 1.0 0.0135419734012732 3.079730523933523e-05 0.0007807071254252 +Fibronectin type III superfamily [IPR036116] 7 13 2.7304331784133704 0.0063251154261654 2.2257281553398056 5.589805825242719 -0.3209057323720775 0.5133796044193292 1.3812257831232946 2.0501463270450144 0.914078257814304 0.3019356379166223 0.0029914489537413 0.295480255529908 0.1487873266068847 0.0015612560180347 0.0209555118054096 +LDL receptor-like superfamily [IPR036055] 5 7 2.691282807131367 0.0071177828138457 1.1577669902912622 2.2135922330097086 -0.4618571585064355 0.3784040995227052 0.963842866820141 1.321226889644718 1.4657719604998898 0.3224476960770873 7.513679532313761e-06 0.0892490045576324 7.736227987690746e-07 3.86876847347757e-06 0.0001982586929064 +Galactose-binding-like domain superfamily [IPR008979] 8 15 2.660876125457103 0.0077937624717672 3.0266990291262137 10.45388349514563 0.2272915730277323 0.4946686484554474 2.0113188873716883 2.8129916124420524 1.0072294248002038 0.3052099564304033 0.0004120846541894 0.0257915242502586 0.0128487417044244 0.0002044748778434 0.0006739327093711 +Glycosyl hydrolase, all-beta [IPR013780] 7 9 2.544548072693044 0.0109419249278588 3.628640776699029 7.919902912621359 0.108448733903935 0.2677010542317815 1.6191976609214136 0.9906808437954988 1.5895506376095985 0.2857304479214345 5.45149776962306e-07 3.066034551708988e-05 8.963260011249366e-08 2.7642156361586266e-07 2.981341174074578e-08 +MHC classes I/II-like antigen recognition protein [IPR011162] 4 5 2.4316198207856634 0.0150314756163449 1.6286407766990292 3.3519417475728157 0.7088257141352072 0.3792248400111384 0.978137271268229 0.8617667089672962 1.1217132539816763 0.2987888107271844 8.990896706297777e-05 0.0847528009868792 0.0126574737404708 5.200397996359343e-05 0.0013249366583681 +MHC class I-like antigen recognition-like superfamily [IPR037055] 4 5 2.4316198207856634 0.0150314756163449 1.6286407766990292 3.3519417475728157 0.7088257141352072 0.3792248400111384 0.978137271268229 0.8617667089672962 1.1217132539816763 0.2987888107271844 2.296556417175484e-05 0.066549445548378 0.0077184558590264 1.31526437712885e-05 0.0003637398802397 +Cadherin-like superfamily [IPR015919] 5 7 2.3348398821966825 0.0195517868797094 1.645631067961165 3.320388349514563 -0.2402178645885725 0.4384898024191497 1.130192585962622 1.2673157339720058 1.2853782186760632 0.3326205753213853 0.0002528400215674 1.0 0.018640880521655 0.0001476913167928 0.0004815297744428 +Concanavalin A-like lectin/glucanase domain superfamily [IPR013320] 4 23 2.321746990974646 0.0202465630717489 5.711165048543689 19.21359223300971 -0.0041595701530016 0.6524236587681258 3.3863764180320586 2.6278954828298513 0.7433396251766937 0.2888580034848961 0.1074717588223361 1.0 0.5943645192903619 0.0740089890485984 0.4717961115976056 +P-type ATPase, A domain superfamily [IPR008250] 5 10 2.116251098265392 0.0343234574091513 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.1184088205118859 1.0 1.0 0.4160065505344545 0.0034687949642114 +P-type ATPase, cytoplasmic domain N [IPR023299] 5 10 2.116251098265392 0.0343234574091513 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.1184088205118859 1.0 1.0 0.4160065505344545 0.0034687949642114 +P-type ATPase, transmembrane domain superfamily [IPR023298] 5 10 2.116251098265392 0.0343234574091513 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.1274683960400928 1.0 1.0 0.4301270919610729 0.0042587077964903 +Alkaline-phosphatase-like, core domain superfamily [IPR017850] 4 8 2.090814384902944 0.0365447061090404 0.95873786407767 2.0315533980582523 0.0900580629775284 0.2707709981894722 0.8039624920145911 1.102281180346787 1.8219170106420324 0.2906549867188161 4.7922469779520365e-05 0.0027067874988798 0.000440337804097 2.7582058036655703e-05 0.000732082482726 +G protein alpha subunit, helical insertion [IPR011025] 5 6 2.0741771769645085 0.0380628590425813 2.2815533980582523 4.327669902912621 -0.2210829368206083 0.5388631009388022 1.380639191550687 1.1285833579715243 0.9314689024130508 0.3098435129808265 1.0 1.0 1.0 1.0 0.0019736987849612 +Nucleotide-diphospho-sugar transferases [IPR029044] 10 28 2.071034127213109 0.0383556069268384 4.893203883495145 18.29126213592233 0.2837763525003371 0.6444920492816484 3.019074060325863 3.0707864587063165 0.6759252525033544 0.2939298573185309 0.2070438818871735 1.0 0.107004894081217 0.1641182363781922 0.0212959388086313 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f9813d2f6010b3a460ca9b7fc012ff876f079f72 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 1053, + "title": "Average number of proteins per term", + "value": 5.253561253561253 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..72ae539f70a6df5cf0d57b3f333890a1db0bfce8 --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a9abd38e8bc38eda422711e027b83fd3112584fd --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,176 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Immunoglobulin-like fold [IPR013783] 0.7753330377520482 3.9522626841529065 7.741569015951022e-05 0.0782874549622639 0.0815187217379653 54 Q04446,P01889,P15260,Q14118,P51805,Q9Y624,P35613,O15031,P55899,O00462,Q8IZA0,Q92673,O94898,P08236,Q7KYR7,P13591,P04439,Q9BY67,P29317,Q08722,P10586,Q92692,Q92859,Q96J84,P10321,P43121,Q15375,P78310,Q6YHK3,Q9Y6N7 30 +Immunoglobulin-like domain superfamily [IPR036179] 0.8121169233628129 3.3588400659198303 0.000782703520896 0.5615500105707836 0.2333414033824314 26 P01889,Q13740,Q13308,Q9Y624,P35613,P55899,O94898,Q7KYR7,Q5ZPR3,P13591,P04439,Q9BY67,Q08722,P10586,Q92859,Q96J84,P10321,P43121,P78310,Q92692,Q9Y6N7 21 +Glycoside hydrolase superfamily [IPR017853] 0.8615806825290702 3.2998933440341736 0.0009672157939459 0.6390338502202029 0.2333414033824314 20 P16278,Q5SRI9,P54802,P06865,O00462,Q9BTY2,P10253,P04062,P07686,P04066,P06280,P08236,Q01459 13 +Six-bladed beta-propeller, TolB-like [IPR011042] 0.8660023119718481 2.805311104546793 0.005026803560062 0.9950411077550592 0.2333414033824314 13 P01130,Q9P273,P14543,Q92673,Q07954,P19021,P98164,P98155 8 +Growth factor receptor cysteine-rich domain superfamily [IPR009030] 0.9252013186985212 2.792571418271624 0.0052290922981086 0.9959968786207236 0.2333414033824314 10 Q04721,P01130,P29317,P14543,Q15375,Q07954,P98164,P48960 8 +Fibronectin type III superfamily [IPR036116] 0.8494893826869905 2.7304331784133704 0.0063251154261654 0.9987461036778854 0.2333414033824314 13 Q92859,P29317,P15260,P10586,Q92673,Q15375,Q9Y6N7 7 +LDL receptor-like superfamily [IPR036055] 0.962886844561319 2.691282807131367 0.0071177828138457 0.9994588567554212 0.2333414033824314 7 P01130,Q9NPF0,Q92673,P98164,P98155 5 +Galactose-binding-like domain superfamily [IPR008979] 0.7971173052368119 2.660876125457103 0.0077937624717672 0.999735846471846 0.2333414033824314 15 O43396,P16278,Q08431,P29317,O00462,Q15375,P08236,O14786 8 +Glycosyl hydrolase, all-beta [IPR013780] 0.885962979339545 2.544548072693044 0.0109419249278588 0.999990698604995 0.2333414033824314 9 O00754,Q04446,Q9BTY2,P10253,P08195,P06280,P04066 7 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.9647849462365604 2.4316198207856634 0.0150314756163449 0.999999881494884 0.2333414033824314 5 P10321,P55899,Q9UNN8,P04439 4 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.9647849462365604 2.4316198207856634 0.0150314756163449 0.999999881494884 0.2333414033824314 5 P10321,P55899,Q9UNN8,P04439 4 +Cadherin-like superfamily [IPR015919] 0.8737284113321125 2.3348398821966825 0.0195517868797094 0.9999999990663884 0.2397385164428271 7 Q14517,Q14574,Q14118,Q9BQT9,O60245 5 +Concanavalin A-like lectin/glucanase domain superfamily [IPR013320] 0.6490870084550735 2.321746990974646 0.0202465630717489 0.999999999557426 0.2440117772932225 23 Q14517,O94813,Q9BQT9,Q7KYR7 4 +P-type ATPase, A domain superfamily [IPR008250] 0.7690897818269417 2.116251098265392 0.0343234574091513 1.0 0.2853469583645326 10 Q9H7F0,Q04656,P98194,Q9HD20,Q9NQ11 5 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.7690897818269417 2.116251098265392 0.0343234574091513 1.0 0.2853469583645326 10 Q9H7F0,Q04656,P98194,Q9HD20,Q9NQ11 5 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.7690897818269417 2.116251098265392 0.0343234574091513 1.0 0.2853469583645326 10 Q9H7F0,Q04656,P98194,Q9HD20,Q9NQ11 5 +Alkaline-phosphatase-like, core domain superfamily [IPR017850] 0.7975255818960855 2.0908143849029437 0.0365447061090404 1.0 0.2853633191103342 8 Q9Y6X5,P34059,P15289,P15586 4 +G protein alpha subunit, helical insertion [IPR011025] 0.8480774401720848 2.0741771769645085 0.0380628590425813 1.0 0.2853633191103342 6 P08754,P09471,Q14344,P04899,P63096 5 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.5877104535228963 2.071034127213109 0.0383556069268384 1.0 0.2853633191103342 28 Q86SF2,Q10472,O60512,Q8N6G5,Q16739,Q68CQ7,O94766,Q9Y673,Q10469,Q10471 10 +SNARE [IPR010989] 0.8078754883362151 1.9093055307853064 0.0562226892532771 1.0 0.3355594154284079 6 O15400,Q86Y82,O43752 3 +Galactose mutarotase-like domain superfamily [IPR011013] 0.8800335452543651 1.8998304866902609 0.0574553687225132 1.0 0.3355594154284079 4 O00754,P10253 2 +Cyclic nucleotide-binding-like [IPR018490] 0.8284723275051984 1.8939951790537757 0.0582256497753497 1.0 0.3355594154284079 5 P10644 1 +L27 domain superfamily [IPR036892] 0.8236559139785015 1.8744474356041063 0.0608687806135297 1.0 0.337357980514777 5 Q12959,Q14168,O14936,Q9NZW5 4 +Immunoglobulin E-set [IPR014756] 0.6009559954633437 1.87210420551033 0.0611921882985018 1.0 0.337357980514777 20 Q04446,P61916,A6NIH7,Q6YHK3,P51805 5 +Papain-like cysteine peptidase superfamily [IPR038765] 0.5333234290394728 1.824534920825497 0.0680712419679263 1.0 0.3551674070944858 32 P07711,P53634,P07858 3 +Porin domain superfamily [IPR023614] 0.8590988006541573 1.816815865669004 0.0692453126408971 1.0 0.3551674070944858 4 P21796 1 +Ricin B-like lectins [IPR035992] 0.8091278672550977 1.8152731512728195 0.0694819428883799 1.0 0.3551674070944858 5 Q9UBG0,Q86SF2,Q10472 3 +Mannose-6-phosphate receptor binding domain superfamily [IPR009011] 0.8078729026098206 1.81014692148064 0.0702730062335428 1.0 0.3574757273619352 5 P11717 1 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.7421513487746999 1.779382196023427 0.0751771233550455 1.0 0.3594776727619573 7 Q8WUJ1,O43169 2 +SKP1/BTB/POZ domain superfamily [IPR011333] 0.7237671270854271 1.7672561658473862 0.0771853372636166 1.0 0.3594776727619573 8 Q96CX2,Q14145,Q9P2R3,Q08380 4 +E2 domain superfamily [IPR036176] 0.9863013698630148 1.7608645874052056 0.0782613249216437 1.0 0.3594776727619573 2 P05067 1 +Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454] 0.9863013698630148 1.7608645874052056 0.0782613249216437 1.0 0.3594776727619573 2 P05067 1 +Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880] 0.9863013698630148 1.7608645874052056 0.0782613249216437 1.0 0.3594776727619573 2 P05067 1 +Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669] 0.9863013698630148 1.7608645874052056 0.0782613249216437 1.0 0.3594776727619573 2 P05067 1 +Beta-Galactosidase/glucuronidase domain superfamily [IPR036156] 0.9857641686811708 1.7586741344443233 0.078632873120743 1.0 0.3594776727619573 2 O00462 1 +Choline/Carnitine o-acyltransferase, domain 2 [IPR042231] 0.8438251024199097 1.7559189614788706 0.0791022468105016 1.0 0.3594776727619573 4 P23786 1 +Metallo-dependent phosphatase-like [IPR029052] 0.7342471795261034 1.744924275255686 0.0809980511603907 1.0 0.3598897006373178 7 Q92485,Q6ZT21 2 +Tetraspanin, EC2 domain superfamily [IPR008952] 0.9779747515444532 1.7268958823386922 0.0841863640804914 1.0 0.3598897006373178 2 O60637 1 +Beta-hexosaminidase-like, domain 2 [IPR029018] 0.9873723804406233 1.72336321131586 0.0848228633216057 1.0 0.3598897006373178 3 P06865,P54802 2 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.7816161275151877 1.702383520841261 0.0886834971678638 1.0 0.3647801660850024 5 P07437,Q9BUK6,Q9BVA1 3 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.5518088676510949 1.6611750112797263 0.0966783027350053 1.0 0.3885582167174069 22 Q6NUM9,P43304,Q9UHG3,Q8NB78,O95831,Q9H9P8,Q14534,P50336,Q8NBM8 9 +C-type lectin-like/link domain superfamily [IPR016186] 0.9682966147232664 1.6514724918407195 0.0986421332070595 1.0 0.3919628915737119 3 Q5KU26,Q9UBG0 2 +C-type lectin fold [IPR016187] 0.9682966147232664 1.6514724918407195 0.0986421332070595 1.0 0.3919628915737119 3 Q5KU26,Q9UBG0 2 +Chloride channel, core [IPR014743] 0.9500402900886432 1.6127277104972766 0.1068036774892533 1.0 0.4029080843477011 2 P51790 1 +Fibronectin type II domain superfamily [IPR036943] 0.9572036664611172 1.6095812648840755 0.1074893009815431 1.0 0.4029080843477011 3 P11717 1 +Kringle-like fold [IPR013806] 0.9572036664611172 1.6095812648840755 0.1074893009815431 1.0 0.4029080843477011 3 P11717 1 +Band 7/SPFH domain superfamily [IPR036013] 0.6868267767213094 1.6010159423610726 0.1093733881664045 1.0 0.4055287948564224 8 O75955,P27105 2 +Spermadhesin, CUB domain superfamily [IPR035914] 0.9427727028479302 1.5550104782518424 0.1199435738252825 1.0 0.4161645590444831 3 O75882,Q6UXD5 2 +NAP-like superfamily [IPR037231] 0.788392054607378 1.532906467712931 0.1252989020695742 1.0 0.4233753921392794 4 Q99733,P55209 2 +Sterile alpha motif/pointed domain superfamily [IPR013761] 0.5924426884531773 1.5257207335062293 0.1270794287057224 1.0 0.4239762549002693 14 Q15375,P29317 2 +Carboxypeptidase-like, regulatory domain superfamily [IPR008969] 0.9304137560451352 1.508225655879908 0.1314967831184021 1.0 0.4319142342065197 3 P16870,O75976 2 +Integrin alpha, N-terminal [IPR028994] 0.9223744292237442 1.499501559236722 0.1337435645095293 1.0 0.4333291490108749 2 P17301 1 +Ankyrin repeat-containing domain superfamily [IPR036770] 0.4854241501309699 1.4695797486334143 0.1416756083951651 1.0 0.4440012370241336 32 Q9H9B1,Q04721,Q86XL3,Q8IUH4,Q96KQ7,Q9ULH0 6 +Alpha/Beta hydrolase fold [IPR029058] 0.4956878030671172 1.460249155827844 0.1442216101224969 1.0 0.4498361973783746 29 Q9UMR5,P50897,P42785,Q9HB40,Q9H3G5,Q8NCC3,P10619 7 +Protein-tyrosine phosphatase-like [IPR029021] 0.5875669970712973 1.438209942908572 0.1503744949110068 1.0 0.4537087196025507 13 Q9NYA4,P10586,Q9ULE6,Q13614 4 +Integrin domain superfamily [IPR032695] 0.9065018807092956 1.4176455478012568 0.1562942751043121 1.0 0.463599638548847 3 P17301,P06756 2 +Glycoside hydrolase families 57/38, central domain superfamily [IPR028995] 0.8871877518130655 1.355674027729966 0.1752029066189044 1.0 0.4932851889564342 2 O00754 1 +Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291] 0.8871877518130655 1.355674027729966 0.1752029066189044 1.0 0.4932851889564342 2 O00754 1 +Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330] 0.8871877518130655 1.355674027729966 0.1752029066189044 1.0 0.4932851889564342 2 O00754 1 +Glycoside hydrolase family 38, central domain superfamily [IPR037094] 0.8871877518130655 1.355674027729966 0.1752029066189044 1.0 0.4932851889564342 2 O00754 1 +Sema domain superfamily [IPR036352] 0.8863819500402939 1.35238702588104 0.1762515376629552 1.0 0.4949143177575782 2 P51805 1 +Galactose oxidase/kelch, beta-propeller [IPR011043] 0.8815471394037184 1.332674399600133 0.1826386779549884 1.0 0.5034516436822064 2 O75882 1 +Cytochrome P450 superfamily [IPR036396] 0.8775181305398974 1.3162605218719745 0.188086616379342 1.0 0.5060036523617187 2 Q16850 1 +Tubulin/FtsZ, C-terminal [IPR008280] 0.7337477658983322 1.3110557913124314 0.1898389151782589 1.0 0.5060036523617187 4 P07437,Q9BVA1 2 +Tubulin, C-terminal [IPR023123] 0.7337477658983322 1.3110557913124314 0.1898389151782589 1.0 0.5060036523617187 4 P07437,Q9BVA1 2 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.7337477658983322 1.3110557913124314 0.1898389151782589 1.0 0.5060036523617187 4 P07437,Q9BVA1 2 +FAD-binding, type PCMH-like superfamily [IPR036318] 0.8745635240397671 1.304232107226634 0.1921544558000518 1.0 0.5071143908708136 2 Q15392 1 +FAD-binding, type PCMH, subdomain 2 [IPR016169] 0.8745635240397671 1.304232107226634 0.1921544558000518 1.0 0.5071143908708136 2 Q15392 1 +RmlC-like jelly roll fold [IPR014710] 0.5808294726272113 1.2239016124359183 0.2209893452803981 1.0 0.5450885614540663 10 Q6P4Q7,P10644,Q96SZ5 3 +MFS transporter superfamily [IPR036259] 0.562575400246544 1.1908049810829204 0.2337301530036173 1.0 0.5533218337630053 11 Q16625,Q8NHS3,Q7L0J3,P41440 4 +MIT domain superfamily [IPR036181] 0.6977591196329185 1.1648335254310522 0.2440863854689512 1.0 0.56935225889371 4 Q6PHR2 1 +Catenin binding domain superfamily [IPR027397] 0.8259000537345479 1.1136891007656504 0.2654125867228785 1.0 0.59727013216617 3 Q14574,Q14126 2 +SH2 domain superfamily [IPR036860] 0.511975678806118 1.0816471677773205 0.2794093372073103 1.0 0.6104794657973601 14 P23458,P07947,O00459,P62993 4 +Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407] 0.8028471662637818 1.0159500628809055 0.3096531671609597 1.0 0.6418942035320294 2 Q9UEU0 1 +SH3-like domain superfamily [IPR036028] 0.4164070815912661 1.0146451044670304 0.3102750305956907 1.0 0.6418942035320294 38 Q5T2T1,P46108,P07947,Q14168,Q14247,P62993,Q9NZW5,Q6XZF7,O14936,O00459,Q96PC5,Q14185,Q9UKS6,Q00013,Q14847,Q9UQB8,Q12959,Q96RU3,Q92783 19 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.5382932662962332 1.0139017142767068 0.3106296533057051 1.0 0.6418942035320294 10 P08183,Q03519,P33527,O14678 4 +Peptidase S1, PA clan [IPR009003] 0.7872094541369032 0.970302050084246 0.3318959557162921 1.0 0.6569294010700294 3 Q2T9J0 1 +HAD-like superfamily [IPR036412] 0.4367176460941365 0.9583814991766064 0.3378704208779539 1.0 0.6625280320009045 25 Q9H7F0,Q04656,P98194,P34913,Q9HD20,Q9NQ11 6 +HAD superfamily [IPR023214] 0.4367176460941364 0.958381499176606 0.3378704208779541 1.0 0.6625280320009045 25 Q9H7F0,Q04656,P98194,P34913,Q9HD20,Q9NQ11 6 +H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664] 0.7867311308084852 0.9526789793223778 0.3407527470515701 1.0 0.665296605700941 2 Q96HR8 1 +PDZ superfamily [IPR036034] 0.4251395201760495 0.9385636733656164 0.3479548111123667 1.0 0.6710557071452786 29 O14641,Q9NZW5,Q00013,Q07157,Q14168,Q12959,Q13425,O14936,Q5T2T1,O00560,Q8WWI1,Q8NEN9,Q96L92 13 +Phosphotransferase/anion transporter [IPR016152] 0.7816277195810032 0.9328081777224108 0.3509190181693884 1.0 0.674302419949573 2 Q9Y6M7 1 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.5275251829757202 0.9140222645859628 0.3607051467654256 1.0 0.6868399991753946 9 P35637,Q92804,Q01844,P52756,P98175 5 +Sec1-like superfamily [IPR036045] 0.5466246166490057 0.9036166991848412 0.3661986833488844 1.0 0.6898161244478984 7 O00186,Q15833,Q8WU76,Q9H267 4 +Sec1-like, domain 2 [IPR027482] 0.5466246166490057 0.9036166991848412 0.3661986833488844 1.0 0.6898161244478984 7 O00186,Q15833,Q8WU76,Q9H267 4 +Hemimethylated DNA-binding domain superfamily [IPR036623] 0.7722266988987343 0.8964358474569616 0.3700200288803956 1.0 0.6943597409237198 2 Q9Y2S7 1 +Kelch-type beta propeller [IPR015915] 0.6237378350279966 0.8682850334082659 0.3852383134045478 1.0 0.7059634920648385 4 O75882 1 +Homeobox-like domain superfamily [IPR009057] 0.4386240702148665 0.849988989284749 0.3953312078988817 1.0 0.7093919667058003 20 Q8NB78,Q99543,Q96G23 3 +Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039] 0.7571850658071464 0.8389316736932592 0.4015076525917371 1.0 0.7141681725998298 2 P13984 1 +Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702] 0.7477840451249188 0.8034741050929465 0.4217007579441336 1.0 0.7327572576157966 2 P05026 1 +F-box-like domain superfamily [IPR036047] 0.5946601309435491 0.7553910494475742 0.4500143820827325 1.0 0.7509748721602493 4 Q6PIJ6,Q13309 2 +Cyclin-like superfamily [IPR036915] 0.7074046823621374 0.6870908019769695 0.492025510111568 1.0 0.7808060861796124 3 P14635 1 +His-Me finger superfamily [IPR044925] 0.7066093498119238 0.6843935068879754 0.4937267150504083 1.0 0.7808060861796124 3 P22413,O94919 2 +DNA/RNA non-specific endonuclease superfamily [IPR044929] 0.7066093498119238 0.6843935068879754 0.4937267150504083 1.0 0.7808060861796124 3 P22413,O94919 2 +EF-hand domain pair [IPR011992] 0.3698964094830028 0.6749134313214035 0.4997307666072779 1.0 0.7852764083566922 56 Q14257,Q9H4M9,P43304,Q15293,P80303,O75071,O43852,Q9NWM8,P0DP25,Q9H8M7,P31949,Q9H223,Q9Y680,Q02818 14 +K Homology domain, type 1 superfamily [IPR036612] 0.3915953419252438 0.6466423577520102 0.5178634372557611 1.0 0.7922684289194147 26 Q06787,P51114,P51116,Q9Y6M1 4 +Chloramphenicol acetyltransferase-like domain superfamily [IPR023213] 0.479166340248164 0.6434279682533428 0.519946440382431 1.0 0.7922684289194147 8 P23786 1 +Ferritin-like superfamily [IPR009078] 0.6914915792241421 0.6337357385757111 0.5262532972797329 1.0 0.7922684289194147 3 P02792 1 +BRO1 domain superfamily [IPR038499] 0.6910263299301396 0.6321960261729059 0.5272587936613027 1.0 0.7922684289194147 3 Q9H3S7,Q8WUM4 2 +Calreticulin/calnexin, P domain superfamily [IPR009033] 0.6874369710235905 0.6203579261243112 0.5350221660092507 1.0 0.7993449873061937 3 O14967 1 +Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155] 0.6935267257587953 0.6080476116651178 0.5431558965491436 1.0 0.8089719364444813 2 Q9H267 1 +GAT domain superfamily [IPR038425] 0.6886919151222309 0.5915494690165872 0.5541523196753775 1.0 0.8195539222165344 2 Q6ZVM7 1 +Ribosomal protein L10e/L16 superfamily [IPR036920] 0.678485092667203 0.5573014966847618 0.5773214532871758 1.0 0.8297912274774657 2 Q9NX20 1 +Sec1-like, domain 1 [IPR043154] 0.4877993844718706 0.5510478667548351 0.5816008618479429 1.0 0.8319140345264429 6 O00186,Q15833,Q9H267 3 +Sec1-like, domain 3a [IPR043127] 0.4877993844718706 0.5510478667548351 0.5816008618479429 1.0 0.8319140345264429 6 O00186,Q15833,Q9H267 3 +Zinc finger, CCHC-type superfamily [IPR036875] 0.4997914822142386 0.5420972215097819 0.5877515327006106 1.0 0.8363545458564094 5 Q9NUD5 1 +AP-2 complex subunit mu, C-terminal superfamily [IPR036168] 0.5339962375705477 0.5326562416847807 0.5942715621971666 1.0 0.8417226437671129 4 Q9BXS5,P48444,Q96CW1 3 +PX domain superfamily [IPR036871] 0.4161182505937015 0.515885604366018 0.6059343089968561 1.0 0.8425650849365812 13 Q9H3E2,Q9Y2I1 2 +Chaperone J-domain superfamily [IPR036869] 0.3822811097424614 0.5073797646395914 0.6118883811099785 1.0 0.8425650849365812 21 Q9NZJ4,Q9NVH1,Q99543,Q9UDY4,Q96KC8,Q8IXB1 6 +Ribosomal protein L22/L17 superfamily [IPR036394] 0.6591458501208867 0.4947468790873141 0.6207788057941561 1.0 0.8445511528938091 2 Q9NWU5 1 +Dedicator of cytokinesis, C-terminal, lobe C [IPR043162] 0.6392712764531 0.4694183941861012 0.6387706029922637 1.0 0.8592586941759267 3 Q14185 1 +Dedicator of cytokinesis, C-terminal, lobe A [IPR043161] 0.6392712764531 0.4694183941861012 0.6387706029922637 1.0 0.8592586941759267 3 Q14185 1 +Leucine-rich repeat domain superfamily [IPR032675] 0.3499849764920331 0.466550219202023 0.6408217100128852 1.0 0.8597574478963544 35 Q8IWT6,Q6PIJ6,O94813,O94898,P39687,Q13641,Q9Y2I1 7 +DNA repair protein XRCC4-like, C-terminal [IPR014751] 0.6478646253021709 0.4597935640011018 0.6456644032867405 1.0 0.8599617169937754 2 Q13426 1 +Rho GTPase activation protein [IPR008936] 0.3813663556757393 0.3630444987675087 0.7165716435443583 1.0 0.8846254339087597 14 O15031,P51805,O00459,Q9H0H5 4 +von Willebrand factor A-like domain superfamily [IPR036465] 0.3580873220909575 0.3116250133143056 0.7553255223255391 1.0 0.9030979684446656 18 P17301,O43405 2 +LEM/LEM-like domain superfamily [IPR011015] 0.4187386202958775 0.2972823092147841 0.7662509866629734 1.0 0.9030979684446656 6 Q86XL3 1 +GINS, helical bundle-like domain superfamily [IPR036224] 0.5734622616169728 0.2631986278031016 0.7923974883839351 1.0 0.9151503130030588 2 Q9BRT9 1 +Sec23/Sec24 helical domain superfamily [IPR036175] 0.4169354838709632 0.2629244404651678 0.7926088180995154 1.0 0.9151503130030588 5 Q15436,P53992,O95486,Q15437 4 +Gelsolin-like domain superfamily [IPR036180] 0.4169354838709632 0.2629244404651678 0.7926088180995154 1.0 0.9151503130030588 5 Q15436,P53992,O95486,Q15437 4 +Ribosomal protein L37ae/L37e [IPR011331] 0.5688960515713101 0.2532824956986939 0.8000499216103938 1.0 0.9217205333213836 2 P61513 1 +Six-hairpin glycosidase-like superfamily [IPR012341] 0.4345285642564991 0.2340703362757444 0.8149303745017402 1.0 0.933755913330068 4 P33908 1 +Translation elongation factor EF1B/ribosomal protein S6 [IPR014717] 0.556809024979853 0.228327232509213 0.8193918551623964 1.0 0.9350532260255836 2 P29692 1 +Translation elongation factor eEF-1beta-like superfamily [IPR036219] 0.556809024979853 0.228327232509213 0.8193918551623964 1.0 0.9350532260255836 2 P29692 1 +Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132] 0.5549288208433996 0.2246153461193461 0.822278525450798 1.0 0.9350532260255836 2 O15382 1 +Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131] 0.5549288208433996 0.2246153461193461 0.822278525450798 1.0 0.9350532260255836 2 O15382 1 +Aminotransferase-like, PLP-dependent enzymes [IPR036038] 0.5549288208433996 0.2246153461193461 0.822278525450798 1.0 0.9350532260255836 2 O15382 1 +EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044] 0.540569586243949 0.2223411439115487 0.8240483253566078 1.0 0.9355911502376338 3 Q9Y2D4,Q6NUQ1 2 +Ribosomal protein S18 superfamily [IPR036870] 0.5484824066612924 0.212238515598865 0.8319209600203483 1.0 0.9419492160230396 2 Q9NVS2 1 +Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045] 0.540424388933657 0.1975305941130606 0.8434123424108331 1.0 0.9498459325133448 2 Q9Y2D4 1 +Zinc finger, Sec23/Sec24-type superfamily [IPR036174] 0.4168234345605995 0.1933835687466664 0.8466585827917912 1.0 0.9498459325133448 4 Q15436,P53992,Q15437 3 +Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151] 0.5369325812516659 0.1914206709142572 0.8481960264457289 1.0 0.9498459325133448 2 Q6P6C2 1 +Rab-GTPase-TBC domain superfamily [IPR035969] 0.3897849462365527 0.1891213035616661 0.8499977449458789 1.0 0.9501567148917308 5 O60343,Q66K14,Q9Y3P9,Q8TC07 4 +GTP-binding protein, orthogonal bundle domain superfamily [IPR023179] 0.5334407735696951 0.1854698951210855 0.8528604908135846 1.0 0.95186824700366 2 Q9NVN8 1 +Translation initiation factor IF-2, domain 3 superfamily [IPR036925] 0.5310233682513993 0.1814432040179253 0.856019709715784 1.0 0.9538505336833022 2 P46199 1 +Beta-lactamase/transpeptidase-like [IPR012338] 0.5302175664786308 0.1801178705424862 0.8570600333823413 1.0 0.9540002274329866 2 P83111 1 +Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162] 0.5280687617512749 0.1766248892760859 0.8598030426296801 1.0 0.9560428763347976 2 Q5JTZ9 1 +Serpin superfamily, domain 1 [IPR042178] 0.5118216012896196 0.170145617457151 0.8648956189617467 1.0 0.9586685123860202 3 P50454,P30740 2 +Serpin superfamily [IPR036186] 0.5118216012896196 0.170145617457151 0.8648956189617467 1.0 0.9586685123860202 3 P50454,P30740 2 +Serpin superfamily, domain 2 [IPR042185] 0.5118216012896196 0.170145617457151 0.8648956189617467 1.0 0.9586685123860202 3 P50454,P30740 2 +Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784] 0.5099408919935428 0.1670685346563512 0.8673161237208702 1.0 0.9603217622303682 3 Q15120,O14874 2 +Oxysterol-binding protein superfamily [IPR037239] 0.359651445991032 0.1647770986164277 0.8691194302795286 1.0 0.9603217622303682 8 Q9BXW6 1 +Ribonuclease III, endonuclease domain superfamily [IPR036389] 0.5181305398871898 0.1612464625733829 0.8718992880323386 1.0 0.9613716757047672 2 Q9H9J2 1 +FERM superfamily, second domain [IPR035963] 0.3425680170246101 0.1585946210448066 0.8739882669429804 1.0 0.9626147385285592 13 P23458 1 +Histone deacetylase domain superfamily [IPR037138] 0.5073865162503334 0.1460412512113769 0.8838888237521298 1.0 0.9674185429008648 2 Q13547 1 +RmlC-like cupin domain superfamily [IPR011051] 0.3639542675704988 0.1291031251118311 0.8972760492238627 1.0 0.9780866250856391 5 Q96SZ5 1 +ISWI, HAND domain superfamily [IPR036306] 0.4848240666129484 0.1187538584140525 0.9054703655608474 1.0 0.9819118442459852 2 P28370 1 +SCP2 sterol-binding domain superfamily [IPR036527] 0.4717893605588301 0.1135299236595602 0.9096104407882062 1.0 0.9843985551387268 3 Q6YN16,P51659 2 +Peptidyl-tRNA hydrolase II domain superfamily [IPR023476] 0.4738114423851722 0.1076088767512811 0.9143059552546612 1.0 0.98846424115314 2 Q9Y3E5 1 +ESCRT assembly domain [IPR037202] 0.4561467474425349 0.0963212028013462 0.9232654719792868 1.0 0.9971267097376296 3 Q9UK41 1 +Bcl-2-like superfamily [IPR036834] 0.3592692421003434 0.0922279449862124 0.9265169357717136 1.0 0.9987684500273604 4 Q9HB09,Q07820 2 +Dynein light chain superfamily [IPR037177] 0.4512489927477829 0.088853822111738 0.92919808294478 1.0 0.998988130805323 2 P63167 1 +PapD-like superfamily [IPR008962] 0.4449220849005816 0.0855699933057838 0.9318082528148466 1.0 0.998988130805323 3 Q8NHP6,Q9P0L0 2 +p53-like tetramerisation domain superfamily [IPR036674] 0.4443847393874151 0.0850875610992401 0.932191779247784 1.0 0.998988130805323 3 Q13043,Q13188 2 +HIV integrase-binding domain superfamily [IPR036218] 0.4450711791565963 0.0846009253048734 0.9325786634203536 1.0 0.998988130805323 2 Q7Z4V5 1 +Translin, N-terminal [IPR016068] 0.4286865431103887 0.07496756061599 0.9402405221159296 1.0 1.0 2 Q99598 1 +Translin, C-terminal [IPR016069] 0.4286865431103887 0.07496756061599 0.9402405221159296 1.0 1.0 2 Q99598 1 +Translin superfamily [IPR036081] 0.4286865431103887 0.07496756061599 0.9402405221159296 1.0 1.0 2 Q99598 1 +HECT, E3 ligase catalytic domain [IPR035983] 0.3201051925099364 0.0613427325442857 0.9510862592113714 1.0 1.0 12 Q96J02,P46934,Q05086 3 +Sirtuin, catalytic core small domain superfamily [IPR026591] 0.3679828095621854 0.0553684348569279 0.9558449425821962 1.0 1.0 2 Q8IXJ6 1 +Translation initiation factor IF2/IF5, N-terminal [IPR016189] 0.3421971528337348 0.052067236340335 0.9584751191527734 1.0 1.0 2 P55010 1 +Translation initiation factor IF2/IF5, zinc-binding [IPR016190] 0.3421971528337348 0.052067236340335 0.9584751191527734 1.0 1.0 2 P55010 1 +Zinc-binding ribosomal protein [IPR011332] 0.3850080601826849 0.0476618729455268 0.9619857205315828 1.0 1.0 3 P61513,P61927 2 +Ureohydrolase domain superfamily [IPR023696] 0.3833960236431913 0.0470237801272283 0.9624942746893694 1.0 1.0 3 Q13547,Q92769 2 +Glutamine synthetase/guanido kinase, catalytic domain [IPR014746] 0.3071754904595486 0.0401735213183373 0.9679547875099488 1.0 1.0 4 O75879,P12532,P48506 3 +CAP Gly-rich domain superfamily [IPR036859] 0.3113917248790862 0.0314808360223109 0.9748860752085118 1.0 1.0 3 Q14203,Q99426 2 +DNA mismatch repair protein MutS, core domain superfamily [IPR036187] 0.3036002149381971 0.0308395320380509 0.975397513395033 1.0 1.0 3 P20585,P52701 2 +DNA mismatch repair protein MutS, N-terminal [IPR016151] 0.3036002149381971 0.0308395320380509 0.975397513395033 1.0 1.0 3 P20585,P52701 2 +MutS, connector domain superfamily [IPR036678] 0.3036002149381971 0.0308395320380509 0.975397513395033 1.0 1.0 3 P20585,P52701 2 +Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410] 0.3006448146157836 0.0306281094837772 0.9755661245354504 1.0 1.0 3 O60884,P31689 2 +TGS-like [IPR012676] 0.3112076230429733 0.030540791637716 0.975635761519548 1.0 1.0 7 Q9NTK5 1 +Riboflavin synthase-like beta-barrel [IPR017938] 0.2931219774314795 0.0301597396425912 0.9759396570243032 1.0 1.0 3 Q9UHQ9,P16435 2 +Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261] 0.2931219774314795 0.0301597396425912 0.9759396570243032 1.0 1.0 3 Q9UHQ9,P16435 2 +HotDog domain superfamily [IPR029069] 0.3105673568163422 0.02470784713651 0.9802879958826938 1.0 1.0 6 P51659,Q8WUY1,Q9Y305,Q9NPJ3,O14734 5 +Prefoldin [IPR009053] 0.3069958470938164 0.0217386968226788 0.9826563954578836 1.0 1.0 7 O15212 1 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b72c4f43222241b5a1b5764d2059b78dd2cc8e82 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily [IPR036971]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "AN1-like Zinc finger [IPR035896]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "APC, N-terminal coiled-coil domain superfamily [IPR036149]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP synthase-coupling factor 6 superfamily, mitochondrial [IPR036204]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Actin-related protein 2/3 complex subunit 5 superfamily [IPR036743]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenomatous polyposis coli protein [IPR026831]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Alba-like domain superfamily [IPR036882]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-dystroglycan domain 2 [IPR027468]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha-macroglobulin, receptor-binding domain superfamily [IPR036595]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Amyloidogenic glycoprotein, amyloid-beta peptide superfamily [IPR037071]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "Apyrase superfamily [IPR036258]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Bcr-Abl oncoprotein oligomerisation domain superfamily [IPR036481]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Beta-trefoil domain superfamily [IPR036358]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CH domain superfamily [IPR036872]", "CKK domain superfamily [IPR038209]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "CalX-like domain superfamily [IPR038081]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Copper type II, ascorbate-dependent monooxygenase, N-terminal domain superfamily [IPR036939]", "Copper type II, ascorbate-dependent monooxygenase-like, C-terminal [IPR014784]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DHBP synthase RibB-like alpha/beta domain superfamily [IPR017945]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DIX domain superfamily [IPR038207]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase delta subunit 3 superfamily [IPR041913]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IA, central region, subdomain 1 [IPR013824]", "DNA topoisomerase, type IA, central region, subdomain 2 [IPR013825]", "DNA topoisomerase, type IA, central region, subdomain 3 [IPR013826]", "DNA topoisomerase, type IA, core domain [IPR023405]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Dedicator of cytokinesis, N-terminal, subdomain 1 [IPR042455]", "Deltex, C-terminal domain superfamily [IPR039399]", "Deoxyhypusine synthase superfamily [IPR036982]", "DhaL domain superfamily [IPR036117]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 2 [IPR042264]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FCS-type zinc finger superfamily [IPR038603]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FMN-binding split barrel [IPR012349]", "FTO, C-terminal domain superfamily [IPR038413]", "Fe-S cluster assembly domain superfamily [IPR034904]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like [IPR012347]", "Ferritin-like superfamily [IPR009078]", "Ferrodoxin-fold anticodon-binding domain superfamily [IPR036690]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavin prenyltransferase-like [IPR036551]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GBBH-like, N-terminal domain superfamily [IPR038492]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GLE1-like superfamily [IPR038506]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP cyclohydrolase 1 type 2/Nif3 superfamily [IPR036069]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-glutamyltranspeptidase, large subunit, C-terminal domain [IPR043138]", "Gamma-glutamyltranspeptidase, small subunit [IPR043137]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "Green fluorescent protein [IPR009017]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "H/ACA ribonucleoprotein complex, subunit Nop10 superfamily [IPR036756]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like, capping domain superfamily [IPR044924]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-loop-helix DNA-binding domain superfamily [IPR036638]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "HesB-like domain superfamily [IPR035903]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Impact, N-terminal domain superfamily [IPR036956]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin alpha, N-terminal [IPR028994]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L1 transposable element, C-terminal domain [IPR042566]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LCCL domain superfamily [IPR036609]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LOTUS-like domain [IPR041966]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "LysM domain superfamily [IPR036779]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex subunit 25, PTOV domain superfamily [IPR038196]", "Mediator complex, subunit Med7/Med21-like [IPR037212]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily [IPR036522]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NFRKB winged helix-like domain superfamily [IPR038106]", "NOB1 zinc finger-like superfamily [IPR036283]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Ndc80 domain superfamily [IPR038273]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Notch-like domain superfamily [IPR035993]", "Nuclear hormone receptor-like domain superfamily [IPR035500]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide cyclase [IPR029787]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAS domain superfamily [IPR035965]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PCGF Ub-like fold discriminator superfamily [IPR038227]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHM/PNGase F domain superfamily [IPR008977]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PINIT domain superfamily [IPR038654]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PLP-binding barrel [IPR029066]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRC-barrel-like superfamily [IPR011033]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PUB-like domain superfamily [IPR036339]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein translocase SecE domain superfamily [IPR023391]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RBP-J/Cbf11, DNA binding domain superfamily [IPR037095]", "RGS domain superfamily [IPR036305]", "RGS, subdomain 2 [IPR044926]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "RUN domain superfamily [IPR037213]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "RecQ mediated genome instability protein, N-terminal, subdomain 2 [IPR042470]", "RecQ-mediated genome instability protein 1, N-terminal, subdomain 1 superfamily [IPR044881]", "Receptor L-domain superfamily [IPR036941]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rel homology domain (RHD), DNA-binding domain superfamily [IPR037059]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S26e superfamily [IPR038551]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rubisco LSMT, substrate-binding domain superfamily [IPR036464]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily [IPR023397]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAP30, C-terminal domain superfamily [IPR038291]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scaffold protein Nfu/NifU, N-terminal domain superfamily [IPR036498]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Secretoglobin superfamily [IPR035960]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Set2 Rpb1 interacting domain superfamily [IPR038190]", "Seven-hairpin glycosidases [IPR036026]", "Sialidase superfamily [IPR036278]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/glucose symporter superfamily [IPR038377]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Sodium:neurotransmitter symporter superfamily [IPR037272]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Somatomedin B-like domain superfamily [IPR036024]", "Spermadhesin, CUB domain superfamily [IPR035914]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "Sushi/SCR/CCP superfamily [IPR035976]", "T-box superfamily [IPR036960]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Taurine dioxygenase TauD-like superfamily [IPR042098]", "Tautomerase/MIF superfamily [IPR014347]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Thyroglobulin type-1 superfamily [IPR036857]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Toll/interleukin-1 receptor homology (TIR) domain superfamily [IPR035897]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription factor EnY2 superfamily [IPR038212]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "UbiA prenyltransferase superfamily [IPR044878]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-associated protein 1, C-terminal [IPR042575]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 [IPR042522]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 [IPR042523]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Uracil-DNA glycosylase-like domain superfamily [IPR036895]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS28, C-terminal domain superfamily [IPR037206]", "VPS28, N-terminal domain superfamily [IPR038358]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "Wiscott-Aldrich syndrome protein, C-terminal [IPR011026]", "XPC-binding domain superfamily [IPR036353]", "XRCC4, N-terminal domain superfamily [IPR009089]", "XRCC4-like, N-terminal domain superfamily [IPR038051]", "YEATS superfamily [IPR038704]", "YggU-like superfamily [IPR036591]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "mRNA decapping protein 2, Box A domain superfamily [IPR036189]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "tRNAHis guanylyltransferase Thg1 superfamily [IPR038469]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADAT3", "ADCY3", "ADD1", "ADD2", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP13", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG5", "ALKBH5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKRD52", "ANKS1A", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APP", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARID4B", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARVCF", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASNSD1", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATM", "ATP11C", "ATP13A1", "ATP13A2", "ATP13A3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5J", "ATP5O", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATRN", "ATRX", "ATXN10", "AURKA", "AURKB", "B3GAT3", "B4GALT3", "BABAM1", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP1", "BAP18", "BARD1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAS3", "BCAT1", "BCAT2", "BCKDHB", "BCKDK", "BCL10", "BCL2L12", "BCL2L13", "BCOR", "BCR", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIP1", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C15orf40", "C1QBP", "C2CD2", "C2CD5", "CAB39", "CABIN1", "CACUL1", "CACYBP", "CAD", "CADM1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CASP8AP2", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX4", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCNB1", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD276", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK7", "CDK9", "CDKAL1", "CDKN2A", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP170", "CERS2", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHORDC1", "CHRAC1", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIT", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLK2", "CLK3", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT10", "CNOT2", "CNOT9", "CNP", "COA7", "COASY", "COCH", "COG8", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPE", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CREG1", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTBS", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMD", "DMXL1", "DMXL2", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENPP4", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERH", "ERI1", "ERLEC1", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM120A", "FAM120B", "FAM234B", "FAR1", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FAT1", "FBL", "FBXO21", "FBXO22", "FBXO38", "FCGRT", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FIS1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FREM2", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALE", "GALK1", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLC", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GGT7", "GIGYF2", "GINS3", "GINS4", "GIT1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLE1", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLPH3", "GOPC", "GORASP2", "GOSR2", "GOT1", "GOT2", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPS1", "GPT2", "GPX8", "GRAMD1A", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GXYLT1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS4", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAK1", "JUP", "KANK2", "KARS", "KAT5", "KAT7", "KATNA1", "KCTD10", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM5A", "KDM5B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFAP3", "KIFBP", "KIFC1", "KIN", "KIRREL1", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L1RE1", "L2HGDH", "L3MBTL2", "LACTB", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LCMT2", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN2", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LRBA", "LRCH2", "LRIG1", "LRIG2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRR1", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYPLA2", "LYSMD3", "LZIC", "M6PR", "MACF1", "MACROD1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MANEA", "MANF", "MAP1A", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBLAC2", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED16", "MED21", "MED25", "MEPCE", "METAP2", "METTL13", "METTL15", "METTL17", "METTL7B", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGA", "MGAT2", "MGEA5", "MGRN1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKL2", "MKRN2", "MMAB", "MMS19", "MOB4", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPG", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL4", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCKIPSD", "NCL", "NCOA5", "NCOR1", "NDC80", "NDRG3", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAF3", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEK9", "NELFE", "NENF", "NEO1", "NEU1", "NF1", "NF2", "NFATC2IP", "NFKBIL1", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NID1", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NME1", "NME2", "NME3", "NME4", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "OAT", "OBSL1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC1", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B3", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PAM", "PAN2", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGG", "PIGO", "PIK3C2A", "PIK3R2", "PIK3R4", "PIP4K2C", "PIR", "PITHD1", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLEC", "PLEKHA5", "PLEKHA7", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNA3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKACA", "PRKACB", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB31", "RAB32", "RAB33B", "RAB35", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54B", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RELA", "REPS1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RMI1", "RNASEH2A", "RNASET2", "RNF14", "RNF149", "RNF20", "RNF213", "RNF219", "RNF31", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP12", "RRP7A", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SBNO1", "SCAF11", "SCAF4", "SCAF8", "SCAP", "SCCPDH", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL1", "SCYL2", "SDAD1", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61G", "SEC63", "SEH1L", "SEL1L", "SELENOI", "SENP3", "SENP6", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGSH", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SIAE", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG6", "SMPDL3A", "SMPDL3B", "SMU1", "SMYD3", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNX1", "SNX17", "SNX2", "SNX25", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORL1", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPECC1L", "SPEN", "SPHK2", "SPOUT1", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STIM1", "STIP1", "STK26", "STK3", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STUB1", "STX12", "STX5", "STX6", "STX7", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SV2A", "SYAP1", "SYDE1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNJ2BP", "TAB1", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRD7", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFRC", "TGS1", "THADA", "THEM6", "THG1L", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM115", "TMEM14C", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOM1L2", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPMT", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC4", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIO", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2B", "TRMT5", "TRMU", "TROVE2", "TRPC4AP", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC38", "TTC39C", "TTC4", "TTF2", "TTI2", "TTK", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP1", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBIAD1", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP32", "USP33", "USP34", "USP36", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIPAS39", "VIRMA", "VKORC1L1", "VLDLR", "VPS11", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "VTI1B", "WAPL", "WARS", "WASL", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR70", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WNK2", "WRN", "WRNIP1", "WWP2", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "YAP1", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCCHC9", "ZDHHC13", "ZFR", "ZFYVE16", "ZMYND8", "ZNF131", "ZNF277", "ZNF280C", "ZNF281", "ZNF512", "ZNF622", "ZNF638", "ZNF644", "ZNF687", "ZNF830", "ZPR1"], "leading_proteins": ["AARS2", "ABCB1", "ABCC1", "ABCD4", "ACOT13", "ACOT8", "ACOT9", "ADGRE5", "ADO", "AIFM1", "ALCAM", "ALG5", "ALKBH5", "ANKFY1", "ANKLE2", "ANP32A", "AP1M1", "AP2M1", "APP", "ARCN1", "ARSA", "ATP13A1", "ATP13A2", "ATP13A3", "ATP1B1", "ATP2C1", "ATP7A", "ATRN", "B3GAT3", "B4GALT3", "BAIAP2", "BCAT2", "BCKDK", "BCL2L12", "BSG", "BTN2A1", "CADM1", "CALM3", "CALU", "CASK", "CCNB1", "CD109", "CD276", "CD320", "CD47", "CERS2", "CKMT1A*", "CLCN3", "CLGN", "CLSTN3", "CNNM4", "COCH", "COLEC12", "CPD", "CPE", "CPT2", "CPVL", "CRK", "CSGALNACT2", "CTBS", "CTSA", "CTSB", "CTSC", "CTSL", "CTTN", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYP51A1", "DAG1", "DCTN1", "DHCR24", "DLG1", "DNAJA1", "DNAJA2", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNMBP", "DOCK1", "DSC3", "DSG2", "DVL2", "DYNLL1", "EEF1D", "EFCAB14", "EHD1", "EHD4", "EHMT1", "EHMT2", "EIF5", "ENDOD1", "ENPP1", "ENPP4", "EPHA2", "EPHA7", "EPHX2", "EWSR1", "EXOC6B", "F11R", "FAT1", "FBXO38", "FCGRT", "FKBP14", "FKBP7", "FLOT1", "FMR1", "FNBP1", "FTL", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "GAA", "GALNS", "GALNT1", "GALNT2", "GALNT7", "GATB", "GBA", "GBE1", "GCLC", "GINS4", "GLA", "GLB1", "GLT8D1", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNL3L", "GNS", "GPD2", "GRB2", "GTF2F2", "GUSB", "HDAC1", "HDAC2", "HDGFL2", "HEXA", "HEXB", "HLA-A", "HLA-B", "HLA-C", "HSD17B4", "HSDL2", "IFNGR1", "IGF2BP2", "IGF2R", "ITCH", "ITGA2", "ITGAV", "JAK1", "KCTD12", "KDM1B", "KEAP1", "KIAA0319L", "KIDINS220", "KIRREL1", "L2HGDH", "LACTB", "LASP1", "LDLR", "LGALS3BP", "LMO7", "LRIG2", "LRP1", "LRP2", "LRRC8A", "MAN1A1", "MAN2B1", "MANBA", "MANEA", "MCAM", "MCL1", "MFGE8", "MFSD8", "MGAT2", "MIA2", "MINDY3", "MOSPD2", "MPP1", "MPP2", "MPP6", "MPP7", "MRC2", "MRPL16", "MRPL22", "MRPL44", "MRPS18A", "MSH3", "MSH6", "MSTO1", "MTIF2", "MTMR2", "MTMR4", "NAF1", "NAGLU", "NAP1L1", "NAP1L4", "NCAM1", "NECTIN2", "NEDD4", "NEO1", "NID1", "NISCH", "NOTCH2", "NPC2", "NRP1", "NUCB1", "NUCB2", "OCLN", "OLA1", "OSBPL1A", "PACSIN3", "PALD1", "PAM", "PCDH7", "PCYOX1", "PCYOX1L", "PDCD6IP", "PDK3", "PDZD8", "PFDN6", "PIK3R2", "PLA2G15", "PLXNA3", "PLXNB2", "POLDIP2", "POR", "PPOX", "PPT1", "PPT2", "PRCP", "PRKAR1A", "PROCR", "PTK7", "PTPN23", "PTPRF", "PTRH2", "RABGAP1", "RACGAP1", "RBM10", "RBM5", "RCN1", "RCN2", "RETSAT", "RINT1", "ROBO1", "RPL37", "RPL37A", "S100A11", "SACS", "SCFD2", "SCPEP1", "SDCBP", "SEC23A", "SEC23B", "SEC24A", "SEC24C", "SERPINB1", "SERPINH1", "SEZ6L2", "SIRT2", "SKP2", "SLC19A1", "SLC3A2", "SLC4A7", "SLIT2", "SMARCA1", "SMPDL3B", "SNTB2", "SNX25", "SNX27", "SORL1", "SQLE", "STAM", "STK3", "STK4", "STOM", "STX12", "STX6", "STX7", "STXBP2", "STXBP3", "SV2A", "TAF15", "TAP2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TENM3", "THEM6", "TJP1", "TMPPE", "TOM1L2", "TPBG", "TSNAX", "TSPAN3", "TUBB", 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176517 diff --git a/interpro_ptm/advanced/plot_1.png b/interpro_ptm/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..8d5064e911edeb15acb8a94970946a727d6d7c7e --- /dev/null +++ b/interpro_ptm/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0b92ee27540718f8f70f917c189c946f61e7fa108a8ef47dbe5b4acdf0c78ae7 +size 177349 diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..bdb151d562a7ff0b9e324f7f5c60c414d13b4f0c --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "1": "P-type ATPase, phosphorylation site [IPR018303]"} \ No newline at end of file diff --git a/interpro_ptm/basic/plot_0.png b/interpro_ptm/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..da91a96df00503b4be87e32ee615aca75ba69760 --- /dev/null +++ b/interpro_ptm/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5450acb3eafc8478044a321d754cd70eae3fc31143d29535940f2e0eb73be72f +size 147981 diff --git a/interpro_ptm/basic/plot_1.png b/interpro_ptm/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..0330ac768eac0406eaf98f4cc8858fef124e557a --- /dev/null +++ b/interpro_ptm/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7cec2237b448249f58fc6a69e6258015b7f62ed88d37fd388dc027fa39fb3c5f +size 140117 diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..147c43d83e1a4051068b7bf7c7967c289627093f --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:38684df238cd32ab0ef8dc1e2fe22e331db4136b5db90c9b0db8603d8cb528fa +size 83555 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8bb6570e0c6613ef69e8c60e55310eeaa5e2bf2b --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +EGF-type aspartate/asparagine hydroxylation site [IPR000152] 8 9 2.77416866159014 0.0055342977658552 1.1703703703703705 2.466666666666667 -0.1373915694631231 0.3902853831950666 1.067180945982341 1.5160051467387146 1.437469353479462 0.3143260829565273 4.383365728727184e-07 0.1665759675679584 0.0004155585626268 1.6510644959116593e-07 5.0413761780603096e-05 +P-type ATPase, phosphorylation site [IPR018303] 5 10 2.116251098265392 0.0343234574091513 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.1184088205118859 1.0 1.0 0.4160065505344545 0.0034687949642114 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0369448957ef3ccae054891a5c819dd3fd0155fe --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 5.25 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..13e6381e68e4aa24768d5427ced8fdfcc3d5f386 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..22d9b085b6ba1de2c98169b6cec24b3c68c2cb0e --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EGF-type aspartate/asparagine hydroxylation site [IPR000152] 0.9418729817007612 2.77416866159014 0.0055342977658552 0.0219540974426405 0.0221371910634209 9 P48960,P01130,Q14517,P14543,O94813,Q07954,P98164,P98155 8 +P-type ATPase, phosphorylation site [IPR018303] 0.7690897818269417 2.116251098265392 0.0343234574091513 0.13038558916995 0.0457646098788684 10 Q9H7F0,Q04656,P98194,Q9HD20,Q9NQ11 5 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5e220603031a864b8c877bb539d88c133e31b4fb --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ADGRE5", "ATP11C", "ATP13A1", "ATP13A2", "ATP13A3", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP7A", "EIF5A", "FASN", "FAT1", "LDLR", "LRP1", "LRP2", "NID1", "NOTCH2", "SLIT2", "VLDLR"], "leading_proteins": ["ADGRE5", "ATP13A1", "ATP13A2", "ATP13A3", "ATP2C1", "ATP7A", "FAT1", "LDLR", "LRP1", "LRP2", "NID1", "SLIT2", "VLDLR"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..2b6078b9a58c6bb89aaa38fdd9b62cb0eaa17295 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "1": "LDLR class B repeat [IPR000033]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..d06a641c37dbeaa9dc1b157d30b8333f8fb8b51d --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:901d990891d67fbf22743cdeb1054e0b2313482530153074514855c990ad5348 +size 188312 diff --git a/interpro_repeat/advanced/plot_1.png b/interpro_repeat/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..7b88228552578bf40a58add2e3668b3428186405 --- /dev/null +++ b/interpro_repeat/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7ccbc44c310e323dc087dec72ba6a84baeb8b2a7d8a0fc607cd78953bf62a5be +size 178015 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..750557f5335f35799d124df9801f3dc2ee085ada --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "1": "LDLR class B repeat [IPR000033]", "2": "Ankyrin repeat [IPR002110]", "3": "Leucine-rich repeat [IPR001611]", "4": "HEAT repeat [IPR000357]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..91cb06188ba92c2e7a48af376206fc446e84150e --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1d36a53a11174cebcbc7defd2b0f0f9a455474bfc7cf9462fdcb5625309b41b6 +size 145462 diff --git a/interpro_repeat/basic/plot_1.png b/interpro_repeat/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..679d5b02e657d03090971437d12338b7069d4ba8 --- /dev/null +++ b/interpro_repeat/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:840f67f9f6706a0a4ef7ee5174306e43c0aa6d347e2ae9c1a25e3699f4a5e541 +size 136560 diff --git a/interpro_repeat/basic/plot_2.png b/interpro_repeat/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..12e162e56cbcb817f09beceb1124f91ea3d54d08 --- /dev/null +++ b/interpro_repeat/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1bc705f8104ea831fc9b2406b4db88276d22412398b555f35b2d28a4dfdceb0e +size 137533 diff --git a/interpro_repeat/basic/plot_3.png b/interpro_repeat/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..f34675d44e9bcb807a981b6ff83466f0cac2aab6 --- /dev/null +++ b/interpro_repeat/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:68883f6d9af3ccdd808a64f639431f9dd325d4fdd7842008151efe5b40c5b849 +size 144211 diff --git a/interpro_repeat/basic/plot_4.png b/interpro_repeat/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..bfc2855748b43ebc049d0f653ba224dead3cfbea --- /dev/null +++ b/interpro_repeat/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a507d0d8987573b9a5b447927b3821e339dc8a65d452162c262a9579859b5f55 +size 138290 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..626049735a0455f1314b766b125618900f21d9a4 --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b27df585ffe99010e385b715847c730ffb568a372c13d281732118946ceba333 +size 89245 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4029ea0c9dd8539bf48507220e036c722d9a25f3 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Low-density lipoprotein (LDL) receptor class A repeat [IPR002172] 5 7 2.691282807131367 0.0071177828138457 1.1577669902912622 2.2135922330097086 -0.4618571585064355 0.3784040995227052 0.963842866820141 1.321226889644718 1.4657719604998898 0.3224476960770873 7.513679532313761e-06 0.0892490045576324 7.736227987690746e-07 3.86876847347757e-06 0.0001982586929064 +LDLR class B repeat [IPR000033] 5 6 2.5516565782471137 0.0107212137866889 0.9836734693877552 1.697959183673469 -0.549615492605431 0.2178830578377484 0.912352182889183 1.204835461019448 2.0954686485482377 0.2766983586353521 1.5365616255530653e-07 0.0526645480715484 3.2670379567832186e-08 7.751339245084413e-08 4.709357290896995e-06 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..68f65ea7906f56d834970b86c97f52a5ac6782a5 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 88, + "title": "Average number of proteins per term", + "value": 5.704545454545454 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1037958259389291ad98324917e86bb8408d5872 --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..579e0feafb59ebbf490d6d03f97eb1eea4210202 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,19 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Low-density lipoprotein (LDL) receptor class A repeat [IPR002172] 0.962886844561319 2.691282807131367 0.0071177828138457 0.4666645479477654 0.1072906435224935 7 P01130,Q9NPF0,Q92673,P98164,P98155 5 +LDLR class B repeat [IPR000033] 0.9688088195751524 2.5516565782471137 0.0107212137866889 0.6127019819656415 0.1072906435224935 6 P01130,P14543,Q92673,P98164,P98155 5 +Collagen triple helix repeat [IPR008160] 0.9503088906795656 1.613826599080019 0.1065650433197804 0.9999506213985226 0.3233697866255406 2 Q5KU26 1 +Integrin alpha beta-propellor [IPR013519] 0.9223744292237442 1.499501559236722 0.1337435645095293 0.9999967424603118 0.3392183469847723 2 P17301 1 +FG-GAP repeat [IPR013517] 0.9223744292237442 1.499501559236722 0.1337435645095293 0.9999967424603118 0.3392183469847723 2 P17301 1 +Plexin repeat [IPR002165] 0.8866200967221907 1.3423562523664412 0.1794805122384823 0.9999999724689218 0.4049816686406782 3 O75882,P51805 2 +Ankyrin repeat [IPR002110] 0.4580719489652397 1.2080632043322483 0.2270229517749016 0.999999999855901 0.4499855983692804 30 Q9H9B1,Q04721,Q8IUH4,Q96KQ7,Q9ULH0 5 +Leucine-rich repeat, typical subtype [IPR003591] 0.4993832117925682 1.1780012824327366 0.2387960949685645 0.9999999999626672 0.4499855983692804 18 Q8IWT6,O94898,O94813,Q13641 4 +NHL repeat [IPR001258] 0.8057660330336376 1.038744223734725 0.2989237077838789 0.9999999999999732 0.5261057256996268 3 P19021 1 +Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547] 0.6237974782290316 0.8685194552242992 0.3851100264556646 1.0 0.5654539599127565 4 Q9H270 1 +Leucine-rich repeat [IPR001611] 0.4135174211134833 0.8339631026306905 0.4043017762211387 1.0 0.5654539599127565 28 Q8IWT6,O94813,O94898,P39687,Q13641,Q9Y2I1 6 +Sel1-like repeat [IPR006597] 0.7316680096696174 0.7436683913297223 0.4570771165701059 1.0 0.618812096279528 2 Q96BR5 1 +Kelch repeat type 1 [IPR006652] 0.6830713714889933 0.6060587837116844 0.5444757190360925 1.0 0.7046156363996491 3 O75882 1 +Importin repeat 4 [IPR041653] 0.570776255707752 0.2573333840040773 0.7969214232641673 1.0 0.8944140386732072 2 O00410 1 +Importin repeat 6 [IPR041389] 0.570776255707752 0.2573333840040773 0.7969214232641673 1.0 0.8944140386732072 2 O00410 1 +Tetratricopeptide repeat 2 [IPR013105] 0.3722117710292886 0.1107897273548415 0.9117830915843504 1.0 0.9703512341876964 4 Q14318,Q02790,Q13325 3 +HEAT repeat [IPR000357] 0.3267885960193715 0.0660663028506972 0.947325038645999 1.0 0.9703512341876964 7 P30153,O00410,Q8TEX9,Q8TF05,Q6PJG6,O60518 6 +HEAT repeat associated with sister chromatid cohesion protein [IPR026003] 0.4053182917002449 0.0648445164029215 0.948297797047067 1.0 0.9703512341876964 2 Q96HW7 1 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ba1eaadffcc7392b9141375aeb5ae42bedb6613e --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Adenomatous polyposis coli (APC) repeat [IPR041257]", "Adenomatous polyposis coli protein repeat [IPR009223]", "Adenomatous polyposis coli protein, 15 residue repeat [IPR009240]", "Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Beta-propeller repeat TECPR [IPR006624]", "BspA type Leucine rich repeat region [IPR026906]", "CSPG repeat [IPR039005]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "FG-GAP repeat [IPR013517]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Fis1, C-terminal tetratricopeptide repeat [IPR028061]", "Fis1, N-terminal tetratricopeptide repeat [IPR028058]", "Furin-like repeat [IPR006212]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "Integrin alpha beta-propellor [IPR013519]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PQ-loop repeat [IPR006603]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "RPEL repeat [IPR004018]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "SAMP [IPR009224]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "YD repeat [IPR006530]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACAP2", "ACTN1", "ACTN2", "ACTN4", "AGAP3", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKRD17", "ANKRD52", "ANKS1A", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "APC", "ARMC1", "ARMC6", "ARMCX3", "ARPC1A", "ARVCF", "ASPH", "ATRN", "BARD1", "BCOR", "BIRC6", "BOP1", "BRAT1", "BUB3", "CABIN1", "CAST", "CD320", "CDC16", "CDC20", "CDC23", "CDC27", "CDC40", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "CNOT10", "COA7", "COLEC12", "COPA", "COPB2", "CORO1B", "CORO1C", "CORO7", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DDX5", "DMD", "DMXL1", "DMXL2", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DYNC1I2", "EDC4", "EED", "EGFR", "EHMT1", "EHMT2", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "ERBIN", "FIS1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FREM2", "GCN1", "GEMIN5", "GIT1", "GLG1", "GLS", "GMPPA", "GMPPB", "GRWD1", "GTF2I", "GTF3C3", "HCFC1", "HECTD1", "HERC2", "HERC5", "HTT", "HUWE1", "IFIT5", "IGF1R", "IGF2R", "ILK", "INTS4", "IPO4", "IPO5", "ITGA2", "ITGAV", "JUP", "KANK2", "KAT7", "KDELC2", "KDM2A", "KEAP1", "KIAA1468", "KIDINS220", "KIFAP3", "KLC1", "KLC2", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "L3MBTL2", "LARP1", "LASP1", "LDLR", "LLGL1", "LRBA", "LRCH2", "LRIG1", "LRIG2", "LRP1", "LRP2", "LRPPRC", "LRR1", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MED16", "MKI67", "MKL2", "MPDU1", "MPHOSPH8", "MRPS27", "MTCH1", "MTCH2", "MTPN", "MYCBP2", "NAA15", "NASP", "NEK9", "NFKBIL1", "NHLRC2", "NID1", "NIPBL", "NISCH", "NLE1", "NLRX1", "NOL10", "NOP2", "NOP9", "NOTCH2", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "OSBPL1A", "P4HA1", "P4HA2", "PAAF1", "PAFAH1B1", "PAK1IP1", "PAM", "PDCD11", "PHIP", "PIK3R4", "PKP2", "PLAA", "PLEC", "PLRG1", "PLXNA3", "PLXNB2", "POLR2A", "PPID", "PPP1R12A", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RABGGTA", "RACK1", "RAE1", "RAI14", "RANBP2", "RANBP6", "RANGAP1", "RAP1GDS1", "RBBP5", "RBBP7", "RCC1", "RCC2", "RNH1", "RPAP3", "RRP9", "RSU1", "SART3", "SCAP", "SCARA3", 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1.1567920478867002 0.2845186374336156 4.051822262152646 3.607380814764068 1.4117439861533438 0.3149022278800241 2.4756215083911576e-05 0.0054233896663051 0.0052630916622981 0.0003558175935407 4.823645240111472e-08 +Regulation of cellular ph 13 26 3.287748210104698 0.0010099211946736 6.885922330097087 20.844660194174757 1.215766922704761 0.2375185297794358 2.9319293283093293 2.765976649626597 1.4143296516981956 0.2875299337708636 5.4448869864970815e-06 0.0017444833819082 0.0012207780133745 0.0001580597168237 4.616436336655448e-08 +Regulation of ph 13 26 3.287748210104698 0.0010099211946736 6.890776699029126 20.859223300970875 1.2151699598837196 0.2373503364294603 2.930458126920059 2.7746402510870145 1.4154672965603718 0.2873526492076106 9.081461175905364e-06 0.002071073147083 0.0015259573241502 0.0002314913891327 1.057373985799136e-07 +Liposaccharide metabolic process 10 23 3.26173492440852 0.0011073263659049 7.393203883495145 16.839805825242717 0.7162233803449398 0.1804705798886219 2.8837934205508033 2.921890590438037 1.8930166841377585 0.2403675114219934 3.44828231602676e-07 8.705688215216705e-06 7.040990558691579e-08 1.0791522063333229e-07 1.6982026956110522e-05 +Lysosomal transport 18 55 3.2540223880476176 0.0011378331225364 10.274271844660197 41.317961165048544 0.2711798693300527 0.4597127484771267 4.560810075793522 6.516846556965687 1.3243780303643906 0.3539546843782676 7.320083571756481e-07 0.0920994578831573 6.586638622768749e-06 1.803206711865558e-07 4.810278927076593e-07 +Carbohydrate derivative catabolic process 18 45 3.222288280180403 0.0012717111273319 9.92233009708738 34.20388349514563 -0.0123085756499559 0.2707665028006943 3.843893961107642 3.291233496452993 1.7787241070250257 0.2878972939517332 1.7873199679067222e-10 1.4451182755582802e-10 4.226875355168847e-16 2.4335802837686488e-11 1.035092669377061e-07 +Membrane lipid catabolic process 10 15 3.204343417002162 0.0013537090220323 5.854368932038835 11.361650485436892 0.500872843713425 0.1363587272813367 1.9603237645724247 0.9867004907377388 2.113024793917032 0.2289617793743788 6.350921680403909e-13 3.752953969462557e-10 6.242696615504472e-12 1.7908617750984817e-13 1.2973700654308505e-11 +Glycoprotein metabolic process 32 79 3.198447131423542 0.0013816986514332 18.59223300970874 59.577669902912625 0.8707431654759812 0.409720724299967 7.543964208858723 9.989377193127202 1.488085349392555 0.3835029669336279 1.1657753305049909e-05 0.0244399028075208 0.0060138761514709 8.677028130186875e-06 4.33681740768938e-06 +Antigen processing and presentation of peptide antigen 6 15 3.0859794959815754 0.002028828120469 4.050970873786408 11.99271844660194 0.9279525789651738 0.3302951212632576 1.9792182503824105 1.8740552023113428 1.0022067378347963 0.2823588878170496 2.8361404923871904e-05 0.0005966319628977 0.0002983067426918 1.3471769237547282e-05 0.0010317596261269 +Steroid metabolic process 22 83 3.053088338657746 0.0022649925083986 17.82766990291262 66.9247572815534 0.9974586731388552 0.3270410156332073 6.090491666967852 5.93996409793671 1.7133199907504504 0.3720334828404655 2.062342632018485e-05 0.0009563326986827 0.0001231487220962 5.19150225262203e-06 1.6376522244390616e-06 +Locomotory behavior 10 33 3.0452970085018984 0.0023245063269718 7.186893203883495 29.01456310679612 0.367578136549174 0.4129867938447028 2.855164467106169 2.964970497634466 1.254834886476281 0.3178953925587394 0.0041409754910179 6.3715997232867216e-06 0.0002948437912435 0.0020435025432918 0.0060704277742298 +Aminoglycan metabolic process 14 23 3.0390029988116587 0.0023736249164387 6.650485436893204 15.218446601941748 0.5538240398360251 0.1973407167351751 2.4739761552565955 2.4752855115427597 1.8355272359461776 0.2521795038965069 6.247928766005316e-11 1.2114709611692025e-05 6.424128499740477e-09 1.2099105430722547e-11 3.315094584142779e-09 +Taxis 29 79 3.026144581717357 0.0024769383197373 15.383495145631068 66.66504854368932 0.0159573551720752 0.6551887547826701 6.206676597495536 8.676742809046639 0.9038937835622892 0.3260534579455081 0.0142481533584885 0.3799377951400663 0.4781211350912649 0.0291492250803966 0.0027078351590228 +Positive regulation of cell adhesion 19 73 3.0150839857561844 0.0025690810592147 13.563106796116504 59.87864077669903 0.0297399042219727 0.7281141229464008 5.285389098319387 7.343832370136682 0.6806550249535446 0.2973683386009694 0.0061082833265976 1.0 0.3468352540469536 0.0375167640954456 0.004299575879678 +Negative regulation of response to external stimulus 19 57 3.013773565031045 0.0025802030281298 9.381067961165048 47.019417475728154 0.8063071074275461 0.4700507256615295 4.127569023520378 6.3589713134688575 0.9364755672970396 0.3491987458588393 0.0007492863442588 1.0 0.2266894976786812 0.0008822013660265 0.0002238273590635 +Cell cell adhesion via plasma membrane adhesion molecules 16 26 3.003732022240464 0.0026669011167816 4.393203883495145 13.847087378640778 -0.0813937198729435 0.5364725215394986 2.8139307454137743 4.13819718991933 1.0044807738527848 0.3140901937753358 0.0003246661894764 1.0 0.1827953867238 0.0133560961650828 1.3097936609855934e-06 +Inorganic anion transport 21 35 2.9747326974675694 0.0029324395145062 9.900485436893204 25.351941747572816 1.3590123122148194 0.2025490755989976 4.608697956226863 4.352203003870329 1.5972877171217004 0.2769639658120273 2.120824321368871e-06 0.0448936661684744 0.0043038530101662 5.422071643948876e-06 2.210969503227436e-05 +Regulation of nervous system development 19 81 2.9665607192642525 0.0030115089008919 12.805825242718448 63.61407766990291 0.2155377588210499 0.7082353007711337 6.12064507741093 7.878266520790482 0.7102203562190534 0.3141420063295854 0.0075348754391429 0.7089333658227114 0.0320816058630327 0.0071099173978038 0.0175471016088091 +Regulation of neuron projection development 28 85 2.957827954972628 0.0030981498838005 13.592233009708735 69.32038834951456 0.4627708713262993 0.6269884749906404 5.824182751460114 9.346058399998094 0.798447623110489 0.3496779713708587 0.0337155547005604 0.7421235934024417 0.2655243330236689 0.0321566031153202 0.0032800146428074 +Glycosphingolipid metabolic process 9 13 2.953253668890224 0.0031444345426419 4.764563106796117 9.184466019417476 0.4485135251287195 0.1553285492394019 1.7516723087054535 1.7320372023153958 1.93068386398988 0.2217231968869004 9.590089351330133e-09 4.9441120883675e-07 2.125047575949681e-08 3.165881378788034e-09 2.265366164990622e-07 +Anion transmembrane transport 22 53 2.9423604400704395 0.0032572056444812 18.02912621359223 42.29854368932039 1.9137296804814252 0.1915609440243116 8.771596162415214 5.032004157423188 1.8922368499585025 0.2935375719655638 3.1272459397715324e-07 0.4251307382490726 0.292624050209727 1.5523970851403116e-05 6.507757149586294e-06 +Protein maturation 15 81 2.937334386636137 0.003310469375688 16.635922330097088 69.29611650485437 0.7279397561088901 0.5092233260742579 5.6828366082703345 6.923625268615643 1.0037762420957868 0.3621314209884535 0.0001105534487643 0.0029218389647841 0.000130057928254 0.0003603471232448 0.0087650767653077 +Ph reduction 9 16 2.932467698025257 0.0033627990253148 4.422330097087379 12.509708737864075 1.1966830084586066 0.1930048880851129 1.91475781321527 1.7851607614701208 1.4167744165903868 0.2497649393583847 8.496955950432245e-05 0.0003334624710947 0.0001376480525375 0.0004897389809093 3.8798819052939275e-07 +Behavior 21 90 2.928704137765622 0.0034037824160542 16.990291262135923 75.04126213592232 0.2909440827671418 0.5405324846032677 5.526186812971979 8.403983472903677 1.109438409605415 0.3578193814797769 0.0003883245399884 5.423336329724208e-06 0.0002583499753073 0.0002876879171492 0.0029823381337073 +Lysosomal protein catabolic process 9 12 2.923349736175981 0.0034628732070134 2.6941747572815533 6.587378640776699 0.838918419522322 0.2080383809566978 1.5899151374262637 1.8707342212441815 1.5239608036504366 0.2420459791980847 2.6926394344892427e-10 0.0034296220851759 5.743981992304903e-07 9.636718304236476e-11 2.0084950438579113e-09 +Protein catabolic process in the vacuole 9 12 2.923349736175981 0.0034628732070134 2.70873786407767 6.618932038834951 0.8383076008345888 0.2101105309103242 1.6017652153393662 1.88837291272598 1.5176899437744062 0.242508547144668 8.86882899872894e-10 0.0042324529563037 1.0236679094826864e-06 3.1912664189315936e-10 7.765261151663103e-09 +Protein processing 14 56 2.914735197118405 0.0035599045533165 12.08252427184466 45.980582524271846 0.9011703887478908 0.3916089016010577 4.43430858840224 4.931040148104543 1.176660792763282 0.3507158233798557 2.31155254091584e-05 0.00056713534557 5.466395454929528e-05 0.000131832282396 0.0011039474506412 +Membrane fusion 26 50 2.895030693480858 0.0037912146024934 11.592233009708735 41.140776699029125 0.24764888033976 0.6429045305046197 5.404397514006145 5.499742922380336 0.8586283816511532 0.3399356769366213 0.0322113287242023 0.4251307382490726 0.6629984443692342 0.1339560302608873 1.565031588603768e-06 +Biological process involved in symbiotic interaction 26 93 2.8736255540087603 0.0040578975110432 16.524271844660195 76.43932038834951 -0.5010535102907213 0.5207152694072219 8.300596142112324 6.579514214979575 1.032159450203337 0.3396665187616686 3.530098972713164e-07 0.0572072173024992 0.0003163340143811 6.480268316031559e-06 3.3018758657205725e-08 +Sphingolipid biosynthetic process 10 20 2.867786801744504 0.0041335397128627 6.543689320388349 16.33252427184466 1.3108583596388097 0.2293036031089034 3.2058099533310203 2.4273143169149307 1.5209865792019848 0.2861850290041513 0.0050448117271522 0.2523879312119707 0.1100932826860655 0.0028705350867404 0.0001042804519188 +Homophilic cell adhesion via plasma membrane adhesion molecules 11 17 2.864865245610919 0.0041718673201105 2.9805825242718447 8.54368932038835 0.0091284588498221 0.5023151287276502 2.0959071651987573 2.502529590250657 1.0648724046913465 0.3160038827031496 0.0002808348072404 1.0 0.0775813155228076 0.0057706709278987 2.0654961033646662e-06 +Neuromuscular process controlling balance 4 13 2.864460448360388 0.0041772031712397 3.8810679611650487 11.723300970873789 0.1269749302219408 0.3318237886495486 1.6788029789058698 1.2889149409291965 1.4027465363164735 0.2954189115293261 0.0004772945250733 1.1398977026944441e-07 3.3768958612978955e-06 0.0002808583984775 0.0062087405568419 +Adult behavior 6 21 2.8452536676687967 0.0044376067864169 4.924757281553398 19.364077669902912 0.6031935344655648 0.4116465050786389 2.137657889318908 2.190772988063693 1.071812274679601 0.3090358289458393 0.0017964561645034 0.0039147102095996 0.0244837275894334 0.000923573561466 0.0370324845913321 +Neurotransmitter transport 17 30 2.839592299596586 0.0045171225068547 6.665048543689321 26.191747572815533 0.4855466408473005 0.5442577786721134 3.0345009262529348 3.012857536994118 0.8354081034116676 0.3113132472759617 0.0628187610578438 0.4018208263035032 0.2640710535308501 0.2425189278137309 0.0001365085595556 +Organic anion transport 20 57 2.8368220199555263 0.0045565003975955 18.575242718446603 46.57281553398058 1.6158560948583975 0.2692356013040078 9.46386426798458 5.9518324529926545 1.7470285445738305 0.3371920110610632 3.442119945985178e-05 0.5097893650742695 0.1608702453512187 0.0025274832620095 0.0001991196582959 +Sterol metabolic process 18 49 2.8362463791053387 0.0045647217075179 11.932038834951456 38.44660194174757 1.1656335789111734 0.2523239777622673 4.346099994655023 4.0619669904912925 1.6676089351046874 0.3062687621764124 2.7568914183769032e-06 0.0082661149627475 0.00132313066272 8.225702041634887e-07 1.6071276191986543e-08 +Phagocytosis 14 48 2.830914378545676 0.004641514430181 8.633495145631068 38.567961165048544 0.0319038557979206 0.6898951952307567 4.3297508187988205 5.612290839266196 0.7929688055011034 0.2962152733283993 0.0133508466178197 0.1106003446312499 0.0253675472895287 0.0069434839747996 0.0004618518718121 +Carbohydrate derivative transport 6 20 2.826978798333873 0.0046989438875153 7.924757281553398 17.024271844660195 1.3665639952580566 0.1869571280171947 4.210097511648942 2.624454303682939 1.5541767319140831 0.2467993156006303 0.0002137935107596 0.0014522342124754 0.0096938597365547 0.0048028453089964 0.0014700047331845 +Cognition 12 43 2.82466815882689 0.0047329605556352 8.381067961165048 35.51456310679612 0.106014143429431 0.585314562092836 3.4293041589801794 4.867395144092575 0.9639094447868622 0.3250247192097197 0.0023779172182811 0.0007775724955623 0.0030750491535246 0.0032384967658702 0.0132360942172494 +Immune response regulating signaling pathway 21 68 2.8222239659668897 0.0047691858197072 11.87135922330097 55.80339805825243 0.3432268025292578 0.6206637713853932 5.259337982730306 7.360527636927723 0.8133581401956841 0.3313585351560056 0.0149695404434828 0.6598101029121848 0.1559477440516821 0.0798372387870115 0.004299575879678 +Multi multicellular organism process 12 36 2.8188278717640225 0.0048199357399696 5.817961165048544 26.4004854368932 0.4199141861061661 0.4886319217993659 2.805744405393114 2.878999920293513 0.979235550100524 0.3132681877599969 0.0080705963926172 0.0007736613442574 0.0089732445190698 0.0166326939811153 0.0002080630135516 +Regulation of neurogenesis 16 71 2.818753351861874 0.0048210547950209 10.95873786407767 57.16747572815534 0.1854107959782945 0.7186584202849315 5.787561684481048 6.504935425520193 0.6629162769918895 0.3069356590994738 0.030172178974667 1.0 0.1487603916010043 0.033678439255046 0.0296219264687003 +Positive regulation of response to external stimulus 15 69 2.8160068065322017 0.0048624636493141 14.03640776699029 59.237864077669904 -0.0988246792844902 0.6482245236244654 5.442206033708916 6.922365840945858 0.8603956617533591 0.3163763423285246 0.0037401667753005 0.0587615611733179 0.0301417198148606 0.01231279423043 0.0067646720627671 +Endosome organization 16 34 2.8112529385374456 0.0049348974108827 7.677184466019417 28.553398058252423 0.1938836583639464 0.5716653902061297 4.453117576534254 5.135972800603594 0.9660014731386156 0.3290604174592388 0.003779912184133 0.0508992589190798 0.034172513126223 0.0087565646797269 0.0091692804635719 +Transition metal ion homeostasis 11 29 2.810443947082413 0.0049473205737828 6.640776699029126 24.57281553398058 0.9239194315613378 0.3015424973151205 2.934079531592402 2.8081087224394015 1.2471169312381896 0.2974369333820005 0.0002954663685265 0.326192706464958 0.0415809882988902 0.0006639209739305 0.000435127860448 +Chloride transport 10 17 2.7930050109741966 0.0052220882988058 4.33252427184466 12.12621359223301 1.0302584084066435 0.2341882174183942 2.3624510960969567 2.26059366569241 1.2797232968088257 0.2563105728143979 2.305048454012345e-05 0.0112943240362007 0.0002651548018521 1.0920782304657888e-05 0.000136080650842 +Lipid localization 27 97 2.7813071019711075 0.0054140494824141 20.1504854368932 74.27912621359224 1.3966421040883936 0.3001252105784707 7.306180038477171 9.39465098860316 1.572418240819249 0.3627304234720817 5.488605428850614e-07 0.0043835120706257 0.0012667041047781 1.5594387716379484e-06 2.7912291857060794e-06 +Neuromuscular process 6 30 2.7809910502395176 0.0054193231153747 6.682038834951456 25.487864077669904 0.5107907507501308 0.3958015985368521 2.5973040014911133 3.0533044809467955 1.2106508695866462 0.3144907539964949 0.0019640886363368 1.6486743933969312e-05 0.0004161253072624 0.0010122977413289 0.0397726884021936 +Amyloid precursor protein metabolic process 5 22 2.7712146702049822 0.005584759438401 5.91747572815534 20.04368932038835 1.2306110398413417 0.2828388345239639 2.574706211328507 3.0661056512526157 1.0127867956133585 0.2841981221806073 0.0035505349025018 0.0296703391700837 0.0001760490995981 0.0020006005653745 0.0162593146466844 +Myeloid leukocyte activation 11 30 2.7643987229346108 0.0057027807149727 4.716019417475728 20.271844660194176 0.1798033859540577 0.5943364469586639 2.7981331640053257 4.1435273532735195 0.8470668099682189 0.3042600455440743 0.0109064797036338 0.0096654361174513 0.0109207585727969 0.0662267021572276 0.0040151312183697 +Receptor metabolic process 13 42 2.757095285957986 0.0058317354804788 8.254854368932039 34.48300970873787 0.1190654259323194 0.6256821363336791 3.854212262351103 4.138641335837385 0.844404065510763 0.3109475309665375 0.0018635560606041 0.3988427362229673 0.003083637252505 0.0121750159919798 0.0004242425877207 +Positive regulation of synaptic transmission 8 19 2.749169692263538 0.0059746446323984 4.813106796116505 17.475728155339805 0.4358203865992658 0.5836764637458288 2.251541663478826 2.30909834121491 0.7613404062503117 0.3040027846338212 0.002758861919529 0.0048225524960019 0.0045315560193572 0.0266777247012389 0.0063938995667289 +Organophosphate ester transport 13 35 2.7437944920014306 0.0060733545766429 10.29126213592233 27.364077669902912 1.4948680330369015 0.1889391065154625 4.84293313185659 4.31957284765524 1.6451867819665518 0.2532208690981375 4.976304311689448e-05 0.3228460923172884 0.0402942577421927 0.0028924350901622 0.000386465762899 +Neuron projection guidance 16 34 2.734564673828981 0.0062462823416997 5.662621359223301 23.189320388349515 0.4437647002001748 0.5678522712486597 2.931294310088859 4.519975354803488 0.8912373776728286 0.311775964869191 0.0034278545878901 0.4847391385004878 0.3700525131557232 0.0014801972688608 0.005370450483445 +Leukocyte mediated cytotoxicity 11 17 2.730822811757093 0.0063176427722164 4.351941747572815 13.985436893203884 0.4021439577883799 0.5004679143122512 2.4135380942775657 1.8380502421368885 0.9762325275008988 0.3133102965191064 0.0014048647062956 0.2027885470531376 0.0096938597365547 0.0244406528674846 0.0014700047331845 +Cellular transition metal ion homeostasis 9 25 2.71712692035895 0.0065851349855956 5.893203883495145 20.42233009708738 0.9608801516152976 0.3243056832171095 2.800529150274697 2.6932649561537056 1.130076157725316 0.3011842711337114 0.0017964561645034 0.2742474624411909 0.0244837275894334 0.000923573561466 0.0010543547733166 +Vacuolar acidification 7 12 2.701195449329614 0.0069090723795797 3.4757281553398056 8.922330097087379 1.27407749822917 0.1611429668415415 1.4148632661931722 1.303016071016461 1.4195929612668792 0.2212670077717619 8.990896706297777e-05 0.0034296220851759 0.0006327439593496 0.0007750266814789 8.168214498131902e-07 +Iron ion homeostasis 9 21 2.6964227193592256 0.0070088658860085 4.468446601941747 17.140776699029125 1.0306963602610326 0.26770320823289 2.1032740346004313 1.762496954108992 1.1437451534606062 0.2692749918411525 6.037340698506789e-05 1.0 0.08610744549237 0.0002044748778434 0.0001381754354709 +Vitamin transport 7 12 2.693422020998824 0.0070722686865876 3.587378640776699 7.597087378640777 1.658661901456128 0.1256251915839625 1.8073839707699664 1.6422194495621811 1.0713624000848283 0.1994200282768667 3.3253048315786296e-05 1.0 0.0219975904219434 0.0002291586350063 1.0603271259838752e-05 +Carbohydrate catabolic process 9 58 2.685989139050688 0.0072315439446002 13.45631067961165 48.04854368932039 -0.4023701280258725 0.4815028531235779 7.512483719225854 3.3199270104758867 1.2356914704034725 0.3542406229670218 0.0001450748338168 1.2672401863175347e-05 6.869934310483315e-08 0.0002513544626297 0.0019355006972274 +Regulation of cellular response to growth factor stimulus 12 43 2.6833581322133915 0.0072886891820522 8.58252427184466 34.092233009708735 -0.0280079791968073 0.708743254851605 4.725523080605279 5.242307157545806 0.6640460187580217 0.2879428696977954 0.0116222448818301 1.0 0.1991829736874783 0.0053640916418316 0.046828773631568 +Positive regulation of cell cell adhesion 12 35 2.6823988404780743 0.0073096255059343 6.548543689320389 29.79126213592233 0.2392641305343646 0.6381877105722645 3.259798197270223 3.572429669961151 0.7925488926612984 0.3104905639319101 0.0020608776223533 1.0 0.3386746096836965 0.0315515858294127 0.0074425863400354 +Ceramide catabolic process 6 8 2.6756084126278776 0.0074593743517845 3.8592233009708736 6.531553398058253 0.1286784152295923 0.1423502941444668 1.429436503356119 0.7012295128365029 2.0219843992394857 0.2259194528389771 6.965404926161271e-09 1.7826192739143463e-09 5.957935356591728e-10 3.124224143496927e-09 3.850375245202498e-07 +Glycolipid catabolic process 6 8 2.673025079648906 0.0075170630351357 3.6310679611650487 6.451456310679611 0.1059933679561382 0.1697430158083476 1.434595381284437 0.7664524352299261 1.9023109688101565 0.2365791262889882 6.965404926161271e-09 2.460833692014816e-07 5.957935356591728e-10 3.124224143496927e-09 3.850375245202498e-07 +Transmembrane receptor protein serine threonine kinase signaling pathway 12 55 2.6692245435014588 0.0076026605188839 10.631067961165048 46.15291262135922 0.2006852178393374 0.6675090539046344 4.897969246836294 6.113284616160956 0.8079382077361186 0.3228563247928272 0.0194445396057651 0.6276501385631038 0.0426118271714143 0.0088309447179168 0.1032544858652068 +Selective autophagy 7 36 2.6628599334826006 0.0077479657521755 7.861650485436893 28.031553398058257 0.6116968756419903 0.5194450063363468 3.450451665126401 4.3159755745103565 0.9002253779314615 0.3454803983634653 0.1076023680550785 0.2813938178053637 0.1355867800667393 0.0780890051531907 0.0151785573456272 +Negative regulation of nervous system development 8 25 2.65533104098618 0.0079230612998346 4.225728155339806 17.99514563106796 0.4680685636974716 0.419713233745777 2.1977522064718618 2.960086545598349 1.0442754970945465 0.2873726818408866 0.0188297521607297 1.0 0.0390282143216565 0.0112163349420639 0.0127721185030957 +Sterol transport 7 30 2.655254972922238 0.0079248483149418 5.516990291262136 23.23058252427185 0.3564989162781894 0.4550431454343515 2.7566693478017315 3.339632072416373 1.1016145306573315 0.3225081354886266 0.0023355066279001 0.2849410889163232 0.1388614812827933 0.0012097891796545 0.016498993555687 +Organelle membrane fusion 19 36 2.653895654507464 0.0079568427746055 9.026699029126211 29.49271844660194 0.2503440438263548 0.5991935201964022 4.297974887399588 5.110663265938685 0.9179616425810708 0.3357137012753883 0.1982323088275875 1.0 1.0 0.3372567641751061 5.207839142730271e-05 +Regulation of neurotransmitter levels 17 32 2.650268548985917 0.0080427813197705 7.553398058252427 29.356796116504853 0.4081983986281809 0.5631164036271649 3.3846545630909723 3.260736921174588 0.8122711518314254 0.3121999516985374 0.3537933556261314 0.4222664170554933 0.2890592178487741 0.7527754475985721 0.0002848525743509 +Secondary alcohol metabolic process 18 53 2.6439396831124777 0.0081947257562393 12.097087378640778 42.24514563106796 1.5200936296432006 0.2566232504859334 4.463475425703621 3.883072640851752 1.3223501002339118 0.3210874999447533 3.541802689472899e-06 0.0088103554061084 0.0014681571022129 1.062553975624555e-06 2.4110350665302625e-08 +Aminoglycan catabolic process 6 7 2.6353415809722542 0.0084052650854808 2.6893203883495147 4.728155339805825 0.5164809724591738 0.1764823388548578 1.1619294817897845 0.7656988020633148 1.69808407883546 0.2279588459746903 6.965404926161271e-09 2.3666612945957126e-05 5.957935356591728e-10 3.124224143496927e-09 3.850375245202498e-07 +Establishment of protein localization to vacuole 8 24 2.634617239852144 0.0084232208817085 4.521844660194175 17.024271844660195 0.4258363140243343 0.4350316278309467 2.7059819557420526 3.223757863278806 1.1181009658786627 0.3126979331758455 0.0001007941332615 0.1828652209005429 0.0006187487433082 4.874947185003326e-05 0.0001194204141374 +Inflammatory response 24 90 2.632589786084998 0.0084736622639851 13.228155339805824 68.3883495145631 0.4116983048649594 0.5194837377797665 5.6022172704029956 8.769134982645609 1.0984550499812151 0.3566163019943059 0.000574041361918 0.1563552271275125 0.0518557866804092 0.0004211639326705 0.0004656914603106 +Immune effector process 25 88 2.622989370408232 0.0087161991892166 15.24757281553398 71.95145631067962 0.1132149302474773 0.7134571835986485 5.865968077599497 7.248540048217676 0.7436652301031837 0.3039621470392462 0.0030455587856886 0.3443282275566168 0.0098035647057395 0.0170967794167786 0.0004084383858722 +Leukocyte proliferation 10 40 2.620392645514009 0.0087828578312267 8.162621359223301 37.15291262135922 0.2981832216609602 0.6690469371584539 3.79131108330846 4.341425682138302 0.7402794541786957 0.3092217445894261 0.012051058270894 1.0 0.1449031461986719 0.0178098913666631 0.033785544222617 +Substrate dependent cell migration 4 12 2.6187948711407563 0.0088240991429102 2.6820388349514563 7.679611650485437 0.0145263325428846 0.5776845741025021 1.936709179276483 1.6411787868327152 0.8851225401144215 0.3126566461447275 0.0014768241824232 1.0 1.0 0.000963248429344 0.0017273216459823 +Glycoprotein biosynthetic process 26 68 2.612492386396969 0.0089884694343862 16.72087378640777 51.87378640776699 1.042113998842759 0.381483262234126 6.756316800759528 8.908847583990125 1.5232206853916193 0.3819786061588057 0.000646734960114 0.2388207944228527 0.1101988716805679 0.0006890981682653 0.0001277500966594 +Protein localization to vacuole 9 28 2.612381873670404 0.0089913758641946 5.20873786407767 20.24757281553398 0.5437651170857908 0.3970016112497027 2.9079938968471533 3.678442701839641 1.178287503307516 0.309681546976434 0.0008196932585148 0.2449590299452383 0.0021465314893355 0.0004129808075874 0.0003597488401456 +Negative regulation of cell development 8 29 2.604285996292936 0.0092065896277586 4.842233009708738 22.570388349514563 0.359297279383123 0.4985276743183016 2.6202836250687755 3.2526907225500694 0.942582430028218 0.3017948582790589 0.0419445349051341 1.0 0.061711249787699 0.0259421126964872 0.0380178364674074 +Positive regulation of cell projection organization 23 81 2.603885202552112 0.0092173624307279 16.111650485436893 64.17961165048544 -0.1586970883128776 0.6547877415164793 8.489694506275146 8.165566576734744 0.7232357301008159 0.2944737374040439 0.0970719212760154 0.6829262542482903 0.3836456925968915 0.1069148524062087 0.0040881425358938 +Organic acid transmembrane transport 13 38 2.59953110506743 0.0093351217856134 12.37621359223301 29.983009708737864 1.9038035525846064 0.1759244630123113 6.520447095353999 3.550222565141749 1.416714921004232 0.2641413901650407 0.0002954663685265 1.0 0.5396055987962411 0.0006639209739305 2.5823112105880053e-05 +Gliogenesis 15 62 2.5991114558617565 0.0093465420832627 10.57766990291262 53.11407766990291 0.3128888864166735 0.6283481078716698 4.440686381801957 5.34345583548812 0.8423545321673526 0.3276548637936928 0.0141938414657159 0.0468986791976777 0.0212485029161671 0.006634350885771 0.0293012600206786 +Antigen processing and presentation of exogenous antigen 4 10 2.596316552848565 0.0094229208075067 2.0800970873786406 7.682038834951456 0.7846141280949802 0.3912377722563422 1.42818099743969 1.069601013737802 0.957994485343778 0.3040877622263243 0.0004772945250733 0.0002365528693072 8.694316847855437e-05 0.0002808583984775 0.0062087405568419 +Vitamin transmembrane transport 4 8 2.595132466178626 0.0094554469168635 2.9344660194174756 6.094660194174757 1.6910321805591797 0.1136175735100163 1.344920850275403 0.8913122381585616 1.0580472895861666 0.1862049292817703 3.368893008845366e-05 1.0 0.1349531130589082 0.000366006536683 0.0005240184523993 +Negative regulation of proteolysis 15 75 2.594454510515085 0.0094741149765689 13.856796116504857 64.19174757281553 0.1536213676829086 0.6668102754358496 6.420263538974692 5.397287151567414 0.8488834550270293 0.3356070904310471 0.0131186334136305 0.0455091327223478 0.0009593316805766 0.0061008858404362 0.0055857571938446 +Antigen processing and presentation of exogenous peptide antigen 4 7 2.592146952495279 0.0095379020580772 1.6067961165048543 4.686893203883495 0.987028524507588 0.2895214995402835 1.1019631322504793 1.05964046762731 1.0509935492639806 0.2645206747413269 0.0001556173554096 0.0001192904084611 3.4550328168080166e-05 9.045491853019026e-05 0.0022125190482932 +T cell activation 18 60 2.580970210332913 0.0098523083028279 11.87135922330097 56.20145631067961 0.3819132128629459 0.6116920144187052 4.9576316669096165 6.2667792486255545 0.7788461990309965 0.3330306669624288 0.0457786608079689 0.6781061210555969 0.375786201091113 0.0496104418903072 0.014845775848694 +Positive regulation of erk1 and erk2 cascade 6 21 2.580681679313126 0.009860545663529 4.29126213592233 16.58252427184466 -0.1278800773081511 0.5315513689884632 2.473671332922706 2.654083762495622 0.9131516716025438 0.2897967566182475 0.0114817371357263 0.2919842266274133 0.4925597827158772 0.0884683246757208 0.0520396071305295 +Cellular iron ion homeostasis 7 17 2.580274648945571 0.0098721765327636 3.66504854368932 13.521844660194176 0.8677978780626455 0.311898632686956 1.8823249793116483 1.671290558583202 1.0630934740559084 0.2702936919112085 0.0005732293183858 1.0 0.0538434207197609 0.0003104448575285 0.000466746230466 +Oligosaccharide metabolic process 6 10 2.5801471440303394 0.0098758224917625 3.0606796116504853 6.179611650485437 -0.0148577354153068 0.2267163537664357 1.4017006052191363 1.1242135739548185 1.7186048285621385 0.2671195008920222 1.6685827108004414e-06 7.272754869097421e-08 1.318928736769531e-09 7.702698179517416e-07 7.472262677160969e-05 +Positive regulation of neuron projection development 12 36 2.578025610575619 0.0099366633072042 5.320388349514563 27.266990291262136 0.1818751734009192 0.6001217862699426 3.530624940508957 3.8010700677703793 0.7786093307846155 0.2947257126705323 0.0419445349051341 0.3713777336871285 0.061711249787699 0.076709375362345 0.0153293256152411 +Antigen processing and presentation of peptide antigen via mhc class i 3 11 2.5760748391828754 0.0099929014807227 3.5533980582524274 10.33980582524272 0.9522781165124746 0.321717188118692 1.7458864571217907 1.7766194475253527 0.972074824811495 0.2764762653101907 0.0026147713450664 0.1026081339138497 0.018640880521655 0.0017174581383874 0.0198699646710478 +Smooth muscle cell migration 9 15 2.5736379993788754 0.0100635505239716 3.7305825242718447 10.385922330097088 -0.3189264558769314 0.4706229844860156 2.237746927414025 1.9306158466576009 1.0411294498318489 0.3050809049980993 0.0223579622998359 1.0 0.3209553841799009 0.0153023562212604 0.0027819419936207 +Carboxylic acid transport 15 41 2.568071241818671 0.0102266136150432 12.351941747572816 33.69417475728155 1.517249458545343 0.2522623764771551 6.23371050940395 4.11174791553619 1.419876490432768 0.3135855212793009 0.0001223594229179 0.4047844567784328 0.0801526286479979 0.0009591833312121 0.0016287622546058 +Protein localization to lysosome 7 19 2.5672639696496424 0.0102504547203372 3.5364077669902914 14.37621359223301 0.6191344010889903 0.3619681772746835 2.0811532251007954 2.18038858944462 1.1869570048706093 0.3022181269423334 0.0004273875299793 0.1665759675679584 0.0004155585626268 0.0002303056568621 0.0003189699178862 +Regulation of chemotaxis 10 29 2.560351958383468 0.0104566203851539 6.492718446601942 26.155339805825243 -0.0174824940836626 0.6237203663336152 3.3301280462202696 3.729330821967613 0.837371285025588 0.3037004773473938 0.0247723014963049 0.3361355940595682 0.552858073626208 0.0499487852123864 0.0021102307461638 +Regulation of pattern recognition receptor signaling pathway 11 25 2.5488969533161314 0.0108064225818147 4.691747572815534 19.70873786407767 0.80673262224624 0.4173389113947272 2.517825740704142 3.173406084005513 0.919675411949683 0.3119180769844089 0.0064357653378577 1.0 0.1194965359594502 0.0622490701590107 0.0007210912957504 +T cell proliferation 8 25 2.5436598980508256 0.010969783610321 6.194174757281553 24.145631067961165 0.2896787294882859 0.6336134652888596 2.9709213778788497 2.668251916718813 0.7427908859202356 0.3020071268550194 0.0383824497634568 1.0 0.2213471409258044 0.0236289755936298 0.0337599745575505 +Regulation of multicellular organism growth 4 16 2.5422957633226426 0.0110126941104997 3.679611650485437 14.067961165048544 0.6235984614772049 0.4457844002979414 1.844506891943582 1.9756386993416857 0.857961107337238 0.2839539709235323 0.002338672529899 0.012648542478749 0.0443091130960601 0.0014099836558107 0.0061413176576109 +Endocytosis 39 145 2.537550167534183 0.0111631367219009 25.6626213592233 116.14077669902912 0.4088637809343856 0.6347066552957155 9.675324480764845 15.608206311139906 1.1645342915127963 0.3689266363473043 2.296820255565157e-07 0.0014325991735347 1.7835163384612016e-07 2.827407332672318e-07 2.867716137340057e-07 +Lymphocyte mediated immunity 11 40 2.535130826202903 0.0112405337992318 8.46116504854369 33.900485436893206 0.1249025253075231 0.6066761672404548 3.501171316061164 3.2683091078637587 0.9080275598841054 0.325794744424275 0.0031120647280036 0.4222664170554933 0.0042512940113116 0.0177743724451021 0.0026925096908203 +Membrane lipid biosynthetic process 10 29 2.527368780564885 0.0114920759642249 8.866504854368932 23.050970873786408 1.3229385051208649 0.2431293012321725 4.229937732502716 3.4850337476777224 1.635527795490498 0.2996124846932806 0.0234951052412779 0.3328373805982222 0.1862598674919939 0.0141287190006936 0.0019118289206985 +Transition metal ion transport 7 16 2.523596029558276 0.0116161329313098 4.70873786407767 14.08980582524272 0.8861898222657586 0.2678437025860737 2.4756329698054333 2.718007722894407 1.3738160036140448 0.271065502827487 0.0751884104816538 1.0 0.4353012614103685 0.1700362094205073 0.0072152122103698 +Positive regulation of leukocyte proliferation 5 17 2.519112947579482 0.0117650910130335 3.861650485436894 14.71359223300971 0.6007881424807215 0.4761380762722816 1.9750347653754128 2.1890082226375087 0.9342511129724644 0.3127219346815347 0.0046345111551306 1.0 0.0181443698350236 0.0127222619547071 0.0212959388086313 +Cell recognition 8 26 2.506398645301908 0.0121968020183806 5.29126213592233 22.859223300970875 0.9056944851933356 0.3618031966115522 2.859598274322472 2.538937048941188 0.9847101891513528 0.3060121099700091 0.001233886009584 0.0358926009784828 0.1163398228410075 0.0006279861154086 0.0025023010526467 +Regulation of leukocyte proliferation 7 26 2.505883469947757 0.012214586825169 5.752427184466019 23.393203883495147 0.3932260927985178 0.5806940436166351 2.797687833832017 3.7032853987829895 0.8370636232955005 0.3221548844899082 0.0168528140178334 1.0 0.0681614338573012 0.031009617990344 0.047600053859417 +Ceramide biosynthetic process 7 13 2.500762876293752 0.0123926122909161 4.033980582524272 10.24757281553398 1.048715387316577 0.2344614502118888 2.237979905601341 2.0281678881596505 1.4071730245015133 0.2685344998940062 0.002338672529899 0.1583124314184509 0.0443091130960601 0.0014099836558107 0.0002117782770131 +Protein targeting to vacuole 6 20 2.500718192191622 0.012394175865843 3.9441747572815538 15.055825242718448 0.398430957984614 0.4200771820268876 2.3315668402653484 2.59373592845287 1.1496285974512008 0.311969859629291 0.0002646566168432 0.1541506060207377 0.0002983067426918 0.0001415457384854 0.0010317596261269 +Regulation of transmembrane receptor protein serine threonine kinase signaling pathway 9 34 2.496872613875002 0.0125293957092473 7.216019417475728 27.59223300970874 -0.0519383977494633 0.6701209774741869 3.707043372113383 4.2275951832081935 0.7338177625451779 0.2919617735055492 0.0131605356098593 1.0 0.1494094536407435 0.0064629825009123 0.0742777556581311 +Myeloid leukocyte migration 8 26 2.4946349407257262 0.0126086774710334 6.196601941747573 24.973300970873787 0.137730749742602 0.6535999513618568 3.1092858273424677 2.579185876047506 0.7446488106428547 0.2967340100846558 0.0407656399904217 0.2919842266274133 0.4925597827158772 0.2385176558358965 0.0063938995667289 +Vascular transport 9 17 2.493867529503001 0.0126359692894506 4.774271844660194 13.094660194174756 0.7274519419599351 0.3186647470404632 2.3913310677559982 2.1617303908189505 1.2183781465172474 0.2807075669512824 0.0021778436913593 1.0 0.0832345551471358 0.0068683859678987 0.0025531684631581 +T cell mediated cytotoxicity 5 8 2.492699328803647 0.0126776149758411 2.3155339805825244 6.371359223300971 0.523676216262352 0.4362981633701682 1.467264629016786 1.0863026706760155 1.002848585470677 0.3105377797682886 0.0001997614514391 0.0981765691424607 0.0170518298819148 0.0133829456596615 0.0003649926190301 +Toll like receptor signaling pathway 9 21 2.491256164229624 0.0127292306896389 3.6529126213592233 14.475728155339803 0.4591583663944621 0.4629288770135975 2.064121680704246 2.5201890058346033 0.9793418922124256 0.3026110620517385 0.0029914489537413 0.295480255529908 0.1487873266068847 0.02815445047553 0.002098592752678 +Muscle cell migration 9 17 2.485171778628843 0.0129488934146255 4.245145631067961 12.262135922330096 -0.2586179539693797 0.4687277297546733 2.50641908492515 2.0548836692490595 1.0581449707808777 0.3025519655210263 0.0457760313357196 1.0 0.3837329617110586 0.03203241935523 0.0098371476265694 +Regulation of lysosomal protein catabolic process 5 7 2.4840175918104617 0.0129909390204121 1.1820388349514563 3.344660194174758 0.359320837781623 0.3612070071329659 1.1335003430162958 1.3137235419699895 1.333216779855555 0.3035682445298419 1.6161281182728312e-06 1.0 0.0031504918831051 9.14133433735114e-07 9.308926617220138e-07 +Regulation of protein catabolic process in the vacuole 5 7 2.4840175918104617 0.0129909390204121 1.2014563106796117 3.3762135922330097 0.3553822840909967 0.3561494889357127 1.140898051797836 1.3189129213804007 1.3434272672921512 0.3030873575434169 5.666738695554048e-06 1.0 0.0047533286028597 3.221304592468962e-06 4.709357290896995e-06 +Protein targeting to lysosome 6 15 2.4831128436322607 0.0130239822726492 2.861650485436894 11.133495145631068 0.4665494631806399 0.3733123029661771 1.8767316131355816 1.7651272451933906 1.2080503341010538 0.3026029882111192 1.435624811949055e-05 0.0981765691424607 4.236608354872846e-05 7.429749655930552e-06 3.857148929638639e-05 +Adaptive immune response 14 52 2.483093677621792 0.0130246830578677 10.065533980582524 42.351941747572816 0.273358349465438 0.6058955707869721 3.753713560137982 4.529827909513841 0.8726173227089915 0.3277958822259462 0.014755565606306 0.1955208267630179 0.0217463504945621 0.0478203719562379 0.0147417162663287 +Pattern recognition receptor signaling pathway 13 40 2.4825389036451924 0.0130449822508054 6.783980582524272 30.48543689320388 0.3893983283533752 0.5277852242642479 3.0860531364168065 4.421623999132768 0.9404779897396882 0.3335139395352661 0.0084216349869502 0.410668613679594 0.0837371519329494 0.0446619282438801 0.0019355006972274 +Glycoside catabolic process 4 6 2.4797361092946506 0.0131479649343186 2.995145631067961 5.604368932038835 0.914408298188202 0.1915126053981477 1.4021397407455505 0.554137429771367 1.5051386650706404 0.245673751384095 7.345286898667587e-07 0.000647621121882 5.454643878372586e-07 4.144367191242097e-07 1.2976991690069218e-05 +Adult locomotory behavior 4 16 2.478427456093485 0.0131962943100287 3.95873786407767 14.822815533980584 0.7389907423501648 0.3383620981823156 1.833016072372531 1.4878680371825237 1.1254592435779416 0.2897204029443448 0.0042473390043545 0.0009649225463882 0.0065760397653667 0.0025916473916576 0.0425821240391988 +Regulation of toll like receptor signaling pathway 8 13 2.4752020562882877 0.0133160815773147 2.587378640776699 9.50485436893204 0.9772136844316576 0.3297728067967737 1.666236944633112 1.8466647258935645 0.9012634534298872 0.2761306672489575 0.005255517230189 1.0 0.3339976348230559 0.0801176308941427 0.0007880746078161 +Mucopolysaccharide metabolic process 6 12 2.4741938409051136 0.0133537220922659 3.400485436893204 8.912621359223301 0.5894446998893683 0.2689339883290864 1.6227448151896249 1.7256308603927724 1.433353391777711 0.275728271795533 0.0001854924478643 0.0204019662414969 0.0091243340822671 9.063996119237736e-05 0.0054986690042778 +Glycosaminoglycan catabolic process 5 6 2.472709620498952 0.0134093048099233 2.6432038834951457 4.665048543689321 0.5167433573606753 0.1777854895826483 1.1305026922003756 0.6751064263980151 1.6910244329591049 0.2288538535307848 1.5365616255530653e-07 1.7811480551971096e-05 3.2670379567832186e-08 7.751339245084413e-08 4.709357290896995e-06 +Oligosaccharide catabolic process 4 5 2.472702082243988 0.0134095876318685 1.2014563106796117 2.3567961165048543 -0.2432795754240238 0.3143165980698041 0.9220585957066318 0.7767104064700684 1.6605983377562186 0.3028711577291625 2.816833245233132e-07 3.8308667598491466e-06 1.5310397798969763e-09 1.5853493324517234e-07 5.068595405713639e-06 +Protein localization to plasma membrane 21 84 2.463088592711363 0.0137745875400847 17.50485436893204 74.02427184466019 0.04078352472809 0.7298603923114082 6.16421521774153 8.588736878541509 0.688616631852129 0.3019343547464078 0.014001811778823 0.2844506340284701 0.6160018336713062 0.1489575669341382 0.000731487664247 +Organelle fusion 29 53 2.46084095453957 0.01386117973486 14.74514563106796 45.383495145631066 0.6448767361523368 0.5292766623385164 6.293825046556003 6.576179389035289 1.1045479661060835 0.3741954647136961 0.2057989022494195 1.0 0.6759110170121503 0.3069279042634235 0.0001412805767695 +Positive regulation of cell killing 5 8 2.457883308349128 0.0139758577652118 2.344660194174758 6.594660194174757 0.4156629456801037 0.4127481983530973 1.3626949423444794 0.9467730739010484 1.1172564974004802 0.3098028662961327 0.0001997614514391 1.0 0.0170518298819148 0.0133829456596615 0.0003649926190301 +Regulation of plasma lipoprotein particle levels 10 18 2.457872058778425 0.0139762955434781 3.0485436893203883 14.031553398058252 0.231208625789076 0.3303314046534408 1.822878555656895 1.834532430195746 1.3070593144112836 0.2560846117575656 0.0013368135220046 0.141543756104335 0.0354914601129098 0.0062346640440273 0.0032807303767948 +Regulation of glycoprotein metabolic process 4 13 2.4496793514260675 0.0142983481074159 3.592233009708738 10.70631067961165 0.6804974065630551 0.4353046559123504 2.03935499608955 1.985055569049905 0.9883671343018048 0.3255557758909779 0.0008261995010786 0.0082126449787597 0.0023694947377154 0.0004897389809093 0.0018986041281287 +Regulation of cell cell adhesion 16 54 2.446761150290522 0.0144146328518763 10.83495145631068 47.220873786407765 -0.0080303092203977 0.6913778743619202 4.947976123233631 6.572393810594877 0.7304846165102299 0.2977646221448794 0.0033484140681752 1.0 0.5818185424731477 0.056003069988558 0.0187965220808016 +Proteoglycan metabolic process 8 14 2.443486516497736 0.0145461131365991 3.0558252427184467 7.347087378640777 0.90943742591388 0.2775323863615319 1.813993622553226 2.3052106999156825 1.19959130355936 0.2714444012698452 1.6584739270054477e-05 1.0 0.3404254693467198 7.157456841530554e-06 0.0001763163996527 +Amyloid beta clearance 4 13 2.4404921727121565 0.014667263797834 2.0509708737864076 9.781553398058252 0.4002973882884584 0.4992490702724125 1.5887419548660706 1.7210432359369072 0.9239665506826532 0.3028953012168623 0.0003159858167221 0.1070183553885475 0.0013262573806951 0.0001850299811141 0.0042587077964903 +Adenylate cyclase modulating g protein coupled receptor signaling pathway 11 21 2.439942538532089 0.0146895982687991 3.8470873786407767 14.407766990291265 -0.2469480880259968 0.5211274524439671 2.574787438137035 2.966436498410936 0.8841726615837232 0.2720064638366494 0.0457760313357196 0.2183837422916212 0.3837329617110586 0.1193188519501932 0.0005793873081042 +Cerebellar cortex development 5 17 2.4365402818094037 0.0148285177755989 3.2014563106796117 12.951456310679612 0.4913835354280507 0.4216383686135529 1.7737836843231067 1.855867843348426 1.0191189701346923 0.2901119129344551 0.0680331793156344 0.012648542478749 0.0443091130960601 0.051542815486873 0.0255449311307142 +Positive regulation of inflammatory response 5 17 2.4305987641979176 0.0150738971416248 3.71116504854369 12.604368932038836 -0.2371758915201458 0.5181114568213592 2.0280967216986476 2.002736075028172 0.9629686677278052 0.3077182349956747 0.0429933331736 0.0239365913087713 0.0115248505447769 0.0300192966842153 0.0300212330028383 +Regulation of cell killing 5 10 2.430171809117195 0.0150916669556091 2.844660194174758 8.366504854368932 0.4041102541319114 0.4507662844932221 1.5842506516490529 1.3031494402288128 1.0522249449787806 0.3118972087461248 0.0011462155823435 1.0 0.0334071197556988 0.0348798008289802 0.0027564644815256 +Exocytic process 10 22 2.427180399268127 0.0152166873327217 5.145631067961165 17.480582524271846 -0.0174643815126957 0.6521122547557453 3.1311394588058663 2.638790479489809 0.7355951712189045 0.2888686915626579 0.7798416055862798 1.0 0.4129317333780675 0.7399484418736413 0.0162593146466844 +Hormone metabolic process 9 34 2.4188987687357875 0.0155675719020114 8.95631067961165 28.65776699029126 1.130508313948193 0.2963365150575847 3.9674689274001818 2.5345884681715156 1.346801337886388 0.3240077568826507 0.0476669074689622 0.0118439766153403 0.0140771202758893 0.0296866330747937 0.0187677828675979 +Negative regulation of peptidase activity 6 43 2.413662076385372 0.0157931020813022 8.29368932038835 36.58252427184466 -0.063782348021029 0.6095822183297694 4.3448059583944065 3.473266199713329 0.8447550419032326 0.3073217557628559 0.0168528140178334 0.0832345551470191 0.0024838215389039 0.0094008643755842 0.102131488895314 +Regulation of response to wounding 9 26 2.4133915988558337 0.0158048284704981 4.351941747572815 17.910194174757283 0.1916937563108336 0.6528179381928949 2.677653137862285 2.7171145748351506 0.6975187302586715 0.2828152410982211 0.0451515119740483 1.0 0.502334803954571 0.0296820907724347 0.0023342102598497 +Myeloid leukocyte differentiation 7 36 2.4099285633882195 0.015955644337172 6.978155339805825 29.5873786407767 0.2011011027578964 0.6062202255251892 3.5082438965963396 4.0029886798733605 0.8431092642014025 0.3149214169729679 0.010406169380635 0.4222664170554933 0.091109134162985 0.0053453327540323 0.1697423450826114 +Import across plasma membrane 14 28 2.4089153303469573 0.0160000094459549 6.601941747572815 18.643203883495147 0.5666543433877399 0.4743790616320767 3.944616106748078 3.664494750162088 1.0498181035479843 0.3397186310535848 0.0043871587170468 1.0 0.5213291194813008 0.0099323103632579 0.0010151666938761 +Regulation of leukocyte mediated cytotoxicity 5 9 2.404385231853914 0.0161996920083706 2.5825242718446604 7.334951456310679 0.4511695306521209 0.4227043221453989 1.4499700153890709 1.2995300672557608 1.082342679990832 0.3098039206468536 0.0003903891768526 1.0 0.0219975904219434 0.0193169154759243 0.0007997701188881 +Glial cell development 5 26 2.400506274760663 0.0163724100497348 5.114077669902913 20.08495145631068 0.342527471970151 0.5482793913252476 2.6656928412824445 3.2664916525364203 0.9072377099594536 0.3081373734674846 0.0069558849956157 0.0380696669646128 0.0225654450263633 0.0039966852967412 0.0319321530393264 +Collagen metabolic process 6 14 2.3970642935079525 0.016527023495644 2.587378640776699 9.830097087378642 0.5446744382123272 0.4689909171837226 1.5071467037844224 1.48463554754042 0.8983431921228839 0.2959543118042154 0.0104036547903649 0.0106429023881486 0.0034893000144238 0.0069928111010265 0.0007020625110616 +Regulation of leukocyte migration 8 28 2.394052758590916 0.0166633517045493 6.080097087378641 26.6504854368932 0.4712165673240142 0.5560717407414059 2.980664549328318 3.842679935245632 0.8934424673809059 0.3310773445531978 0.0474461528933714 0.0496758524768897 0.1554832015057707 0.0994768290011166 0.0084030412621332 +Regulation of lysosomal lumen ph 5 7 2.3910270079936464 0.0168013168899925 2.3567961165048543 5.58252427184466 1.1719038900849827 0.159040563248536 1.2351555175791742 1.4280428037740598 1.4707016211600112 0.2132438131163355 0.0005664524138943 0.0023758658868836 0.0003602808960722 0.000366006536683 4.318273591764818e-05 +Peptide catabolic process 3 12 2.3869056390013808 0.0169908516803984 3.871359223300971 10.351941747572816 1.5413280472635258 0.1625248535751528 1.454973091229298 0.9501768442987896 1.1353491763523988 0.2229381591694359 0.0014768241824232 0.0038211367015083 0.0007461625149634 0.000963248429344 0.0118045746321095 +Cellular response to thyroid hormone stimulus 1 6 2.386184846442014 0.0170241917856663 1.5364077669902914 3.783980582524272 -0.0182361511381738 0.5426463854639296 1.1260958885596448 1.037844891609742 0.986387597890034 0.3162311735237332 0.0341781603031309 0.0012601973854463 0.0047533286028597 0.0276231155809849 0.0964811850177102 +Regulation of protein localization to plasma membrane 8 33 2.3833027371350592 0.0171580774917912 7.063106796116505 27.233009708737864 -0.027006311500756 0.7397788460473858 3.625810663724337 3.2477143075102393 0.5807274162281139 0.2593507041587613 0.004074968927174 0.0521335433076176 0.162236447621752 0.0345747530672156 0.0031709677504383 +Negative regulation of glycoprotein metabolic process 2 5 2.3810165435712136 0.0172649365660857 1.1237864077669903 2.9150485436893203 0.4709960836391295 0.3904285331302831 0.8655865248767802 1.0928126832857985 1.3043889305991798 0.3156095962580754 0.0014601836592373 0.0008300469730069 6.936272072908627e-05 0.0010464818333657 0.0076273123324074 +Astrocyte differentiation 3 16 2.379957004186568 0.0173146581824383 3.094660194174758 11.42233009708738 0.0584209125016935 0.5547337588992057 2.207285076469246 1.943694412377063 0.913626470884625 0.299483644308788 0.0188291495256045 0.0148056693212618 0.005693097574516 0.0128293519549119 0.0351185939844577 +Cytosolic transport 24 72 2.376889554650108 0.0174593149115762 15.3252427184466 64.33980582524272 0.1744021984538085 0.6762754968826091 7.447619264441359 7.422157064915613 0.8339042857759891 0.3289347094763193 0.0613999778372133 0.538277640080983 0.0632048376565007 0.0351743267040848 0.0086209630771813 +Glycoside metabolic process 4 9 2.3759455752391885 0.017504044398813 3.283980582524272 8.611650485436893 0.5062828222010527 0.3204164092287125 1.4990079825210394 0.6824144700308834 1.298018080705215 0.2868097664691992 3.368893008845366e-05 0.0023758658868836 1.0100053103379697e-05 1.934192081629664e-05 0.0005240184523993 +Apoptotic cell clearance 3 10 2.375167784369345 0.0175409746739154 1.4150485436893203 8.16747572815534 0.7343377868729896 0.4133364508748849 1.6160802235364573 1.40166698151907 0.89060803593971 0.2988103853625464 0.0159045536144147 1.0 1.0 0.0116756742779249 0.0142025885279179 +Membrane docking 15 35 2.37000286725952 0.0177879473139939 7.973300970873787 28.83252427184466 0.3013065671948621 0.638505559524285 3.967313754164099 3.197937811998676 0.8147042438070861 0.3288047187933706 0.1120369345362934 1.0 1.0 0.2256891642594976 0.016498993555687 +Microglial cell activation 3 5 2.368976551025481 0.0178373843226882 1.1582914572864322 2.597989949748744 0.0723242975485896 0.3616043522536503 0.973296267122896 1.100112365160666 1.5501663225319051 0.3208745890680372 0.0003096916980164 3.066034551708988e-05 5.369271916582234e-06 0.0001991597833083 0.0027426851014433 +Leukocyte migration 14 51 2.3674857623169947 0.017909409105236 10.118932038834952 46.80582524271845 0.3575882448711393 0.6313812887885496 4.534434682359551 5.391125848207169 0.8213013384586727 0.3308801783294869 0.0325307976298464 0.145012854682081 0.3803883597337516 0.1138666570015389 0.0025684370412001 +T cell mediated immunity 6 14 2.3649276283341543 0.0180335945781724 3.0145631067961167 10.46116504854369 0.1197287002677679 0.5708409161470714 1.5856705277946497 1.582963486610934 0.8689627261999604 0.297636200564505 0.0064222178805025 0.1948770046367652 0.0666692325567911 0.0893115916137597 0.0048404074215544 +Associative learning 5 15 2.357172595648062 0.0184146857281299 3.2985436893203883 11.640776699029129 0.5833637693792252 0.3608696253992166 1.7586672512213413 1.9907766398439397 1.1416749351319833 0.2853176800833586 0.0030051438102713 0.0007667347448651 0.0052800410185589 0.001820540651884 0.0081074498059467 +Autophagosome maturation 6 21 2.356990290612658 0.018423728570005 4.742718446601942 17.16747572815534 0.0817445188148652 0.5991875967567871 2.8484061951846895 3.5558799160779064 0.838769675601762 0.2978968014658341 0.1593580878422053 0.2222355866483168 0.08610744549237 0.124643595331372 0.0109403402937121 +Regulation of long term synaptic potentiation 3 7 2.356820894248121 0.0184321345889317 2.191747572815534 6.026699029126213 0.6105178624452509 0.3860292464291884 1.2788913032023987 1.4948993461258857 1.1199694698848182 0.3107967468650517 0.0036403935965265 0.0002088865488349 0.0015052123544451 0.0024022577840735 0.0267540631687978 +Cell activation involved in immune response 13 46 2.3562392593042034 0.018461022832545 7.424757281553398 37.133495145631066 0.2013804059718359 0.6332706700932498 3.985004499798946 3.76547221312819 0.8111784803604789 0.3140247982994989 0.0628752477074632 0.4743715197669595 0.0363983757034302 0.0378423114252983 0.010225908301837 +Regulation of t cell proliferation 6 18 2.3540597183178296 0.0185696275197553 4.548543689320389 17.20873786407767 0.3678090213411445 0.5562508690900512 2.4712075613347495 2.4125725220194325 0.8250230708720367 0.3041137280888924 0.0407656399904217 1.0 0.1454623761357323 0.0266777247012389 0.0520396071305295 +Neurotransmitter secretion 11 22 2.349886227505125 0.0187791501164338 4.878640776699029 19.800970873786408 0.4739837619437216 0.5379742436571602 2.5178643472114657 2.5013004441236206 0.8040908235944773 0.3018218439933647 0.6554129606378716 0.3328373805982222 0.1862598674919939 0.592458577023541 0.0173345468362617 +Regulation of cell activation 19 75 2.3478901061993445 0.0188800907761474 13.849514563106796 65.59223300970874 0.0117954500841862 0.6466994765328734 5.255295503804918 8.314435794837985 0.810235540435219 0.3149538466828337 0.0266488842024114 0.730136381958832 0.0408976472683376 0.053902604248962 0.0306017146609725 +Natural killer cell mediated immunity 8 12 2.3456199741602477 0.0189954641134735 3.0266990291262137 9.79611650485437 0.3581391067116419 0.5074304089326694 1.9300298746867943 1.587935236879548 0.9456543485669218 0.3100992296137194 0.0092969246962044 1.0 0.0354914601129098 0.0379489226270714 0.0032807303767948 +Regulation of nervous system process 8 16 2.343351974942931 0.0191113441732106 2.6941747572815533 11.186893203883496 0.709685710886722 0.4267375683332639 1.6891041598029932 2.2483053074671338 0.9287991925104498 0.3050882814355576 0.0516359319424872 0.0267403422938185 0.0890100643743446 0.0362911702166911 0.0121306067054488 +Positive regulation of cell junction assembly 6 16 2.3432921226721923 0.0191144105875384 3.063106796116505 10.70631067961165 0.202527500453485 0.5734869063143083 2.267520363799425 1.8098058096179055 0.8320845471156263 0.2984713165760313 0.0017593449405271 1.0 0.371655018795122 0.0280832529132891 0.0078773866774108 +Mononuclear cell migration 7 24 2.337113777294397 0.0194332688290692 6.058252427184466 23.645631067961165 0.0105016163762546 0.6303901682999394 3.102067092594892 2.7844323365283423 0.8660601863335294 0.3059427019687199 0.0086986300631638 0.0414278249847813 0.1323300889211223 0.0050344975307554 0.0139364810386785 +Sphingoid metabolic process 4 6 2.335532744622022 0.0195156073805695 2.337378640776699 5.174757281553398 0.8258730035764346 0.2192038420096116 1.196784089801513 0.5941001920342514 1.4738240163378542 0.2563928956394505 0.0284648775398106 0.0479914252810258 0.0921025797166938 0.0229613270793894 5.383729574080712e-05 +Membrane biogenesis 8 25 2.329997415147351 0.019806287735882 5.650485436893204 23.37378640776699 0.4076887649308771 0.5488195500053573 2.840274627307328 3.3798506649680777 0.8254499092994252 0.3113415949903997 0.0352357879630262 1.0 0.3593428278464597 0.6756630435254583 0.0003026550720459 +Iron ion transport 5 12 2.3266535136087643 0.0199837138923915 2.8762135922330097 9.3252427184466 0.6984692822717036 0.3339124009240178 1.7603279794274296 1.4434464182805606 1.1549328537786283 0.2828654848729625 0.058960012286042 1.0 0.2732850813359189 0.0444854600227105 0.0045472220952188 +Endosomal transport 25 86 2.3195522019632286 0.0203651140958811 18.62621359223301 73.93932038834951 0.1186519085167339 0.644720288610979 8.11663114827185 10.15480695988343 0.8992829354823526 0.3430729564402452 0.0979120954793953 0.2607027479133809 0.1297043702732698 0.056003069988558 0.0092052942082856 +Chloride transmembrane transport 7 8 2.31673034572165 0.0205184254434094 1.9271844660194175 5.497572815533981 1.0121969151812915 0.2503571453769561 1.6864793094247907 1.5080669592016671 1.1003731395705292 0.2453144412674818 0.0009463420108467 0.0802348466038066 0.1515272625734178 0.0006143549700213 0.0009961752813945 +Vesicle docking 9 19 2.31533056631864 0.0205948481914395 5.046116504854369 16.300970873786408 0.2955335573812314 0.5566344803804099 2.726231700974349 2.3037957343391864 0.8857805503827542 0.3078464388536641 0.032846548252385 1.0 1.0 0.0940672040532474 0.0205399046658008 +Regulation of protein localization to membrane 11 52 2.315061412212048 0.0206095714215883 10.677184466019416 43.199029126213595 -0.0710500739564337 0.7469779660824316 4.398826391910286 5.302884270062466 0.5665828398548924 0.262748836690835 0.0067955967516098 0.1250660932411784 0.3386746096836965 0.0315515858294127 0.0074425863400354 +Negative regulation of hydrolase activity 12 69 2.3102284731063483 0.0208755084740512 13.71359223300971 61.55582524271845 -0.0365477234421551 0.6686475173700427 6.008126350326953 6.2538756952931465 0.8021313488618124 0.3189731412355006 0.0178164293671684 0.204463696732403 0.0243497840139476 0.0084543321510107 0.0717391220215889 +Organic acid transport 18 57 2.3085764370700947 0.0209670967304222 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 0.0012132415179287 1.0 0.3803883597337516 0.0058885527356408 0.0009439226313989 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 6 18 2.304876164290464 0.0211735098962488 3.70873786407767 13.225728155339803 0.1207945387582695 0.6056782907647003 2.351950514476632 2.015719343011274 0.8095159596863328 0.2961773927622835 0.0059445020950885 1.0 0.0207328276809773 0.0033989983353886 0.0273247630743773 +Response to thyroid hormone 2 9 2.304516697371848 0.0211936561429642 1.7087378640776698 6.662621359223301 0.3704077449468085 0.4940041388056373 1.616847393661985 1.1235609662945203 0.8929316466794897 0.2904037257022112 0.0137899394557154 0.0038211367015083 0.014058804472369 0.0101015401572799 0.0615084186624239 +Intracellular lipid transport 5 18 2.3032304616560646 0.0212658797811409 3.2475728155339807 12.529126213592232 1.0333463606041455 0.2805251274605093 1.854375285913986 2.478377603832177 1.0146678848168829 0.2521579143644115 0.0017867527116645 0.1499686155438198 0.0398064357050217 0.0010720436073174 0.0045472220952188 +Positive regulation of long term synaptic potentiation 2 5 2.2982303797813755 0.0215486804930991 1.0946601941747574 3.1432038834951457 0.4266913694171521 0.4125553626995947 0.8292414542136507 1.102238422917561 1.2242523524253524 0.3132175218460173 0.0045876876261238 3.066034551708988e-05 0.0002296483500821 0.0033170374819039 0.0224777557227792 +Regulated exocytosis 15 41 2.296293980426708 0.0216590780582017 9.385922330097088 34.342233009708735 0.5889869251407832 0.528096964379338 3.868480531815476 4.573760415025692 0.9122431884356956 0.3457208176316948 0.6462154389270542 1.0 0.3281099840481742 0.7977158209973941 0.0060852485432391 +Amyloid precursor protein catabolic process 3 17 2.293444607602351 0.0218224209692434 4.62621359223301 16.47087378640777 1.203006467000838 0.2754962460876 2.1329801006381106 2.1803683249886516 0.947433834000198 0.2709877848980267 0.0305551934453896 0.1948770046367652 0.0085749794431607 0.0211003003498726 0.0601700233302374 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 12 40 2.286423695066671 0.0222294834277083 7.757281553398058 32.31310679611651 0.1415333879820327 0.6037463529133537 3.504410589660101 3.044416034085123 0.8740255675036868 0.3157880382593289 0.0161129054975261 0.4475497772550058 0.028278569718715 0.0701527069806367 0.0052957140448635 +Mating 1 5 2.284921864266143 0.0223174097478828 1.296116504854369 4.12378640776699 -0.0749270475296282 0.3679325751810022 0.937194981329158 1.089097440971999 1.345984464291908 0.2988095708193542 0.0536294646385174 0.0020655426456597 0.0077184558590264 0.0435926191526008 0.1453218662998846 +Axon development 29 95 2.284814015583896 0.0223237354880632 15.014563106796116 75.88349514563107 0.4221802741874887 0.6742105443551618 6.65661081388802 8.797672872875632 0.8036898770047755 0.340363217999487 0.0060571280440104 0.7681010821672454 0.5381411976223549 0.011560027252802 0.0082201294947124 +Sodium ion transport 11 30 2.284792481459077 0.0223249987340432 7.286407766990291 24.194174757281555 0.366064924510469 0.599746317765829 3.595508215659048 3.4684661348618055 0.8333080580344709 0.3307550501478689 0.0457085230346741 1.0 1.0 0.0822680536417182 0.017564228185315 +Cholesterol efflux 4 9 2.283878997535129 0.0223786432736592 2.5485436893203883 7.621359223300971 0.5111997846274834 0.3340620166024763 1.4780178328121285 1.039197831548229 1.1947983633918562 0.2643278716774433 0.0006938370115112 0.1244478155008913 0.2297987482657219 0.0004102788019959 0.0087126791211197 +Astrocyte development 3 9 2.282555990343445 0.0224565358376349 1.662621359223301 5.529126213592233 0.4384947546692366 0.3812983981533123 1.2148997810479618 1.4027110413850483 1.1577934925672642 0.2956958593053811 0.0011910371662417 0.0034296220851759 0.0006327439593496 0.0007750266814789 0.0096830476876922 +Positive regulation of mononuclear cell migration 4 9 2.2797204745960062 0.0226242721804934 2.8762135922330097 9.45873786407767 0.0886382248774921 0.5417098390792167 1.6300328286079158 1.7054300369397768 0.9929662660604948 0.3187573347288022 0.0322196793383797 0.007105321595433 0.0255840399150975 0.0239571113561098 0.0073870683046854 +Toll like receptor 3 signaling pathway 4 6 2.277510693827315 0.0227557467703467 1.5024271844660195 3.9733009708737863 0.6601209002896212 0.3693199456727258 1.102730033258955 0.8543241106954446 1.0886679509585764 0.2940947508268549 0.0007392957286029 0.0756950383436983 0.1432798584585485 0.0557098434243155 0.000732082482726 +Interleukin 6 production 4 17 2.27698383024924 0.0227871912298571 3.5364077669902914 13.567961165048544 0.0983164115113158 0.5887576448929882 2.0997306134978513 1.8754268688059847 0.8127720777562529 0.2844444787780972 0.0486569865865319 0.2222355866483168 0.3896854720293997 0.0341229578056568 0.099423410284734 +Lipoprotein metabolic process 7 29 2.2729353882738863 0.0230300738484474 5.504854368932039 19.114077669902912 1.0723975558987071 0.2794846862458811 2.648039342123219 3.7213756556771336 1.2556798055308762 0.2951644225033464 0.0274640329570685 0.3426841548479852 0.0483217377147592 0.0166326939811153 0.0531143503184548 +Positive regulation of t cell proliferation 3 11 2.2716808715954424 0.0231057923443571 2.7475728155339807 9.599514563106796 0.5532192709084727 0.4333591055805664 1.6218678348817797 1.3191273068698348 0.9842106594117432 0.3010582825504118 0.0156685252191865 1.0 0.0466281418945222 0.0106277501006418 0.0285239329034339 +Negative chemotaxis 4 5 2.270575616283947 0.0231726809576111 1.2627737226277371 2.7493917274939172 -0.0970013366332108 0.4702470366204203 0.8900920397967278 1.0266371388759516 1.207803474245195 0.3249890709501151 0.0232832774509756 1.0 1.0 0.0172025832638257 0.0042587077964903 +Positive regulation of defense response 9 47 2.2691893670162444 0.0232568125986443 9.526699029126211 39.58495145631068 -0.1121342674830764 0.6770564562992223 4.421018397009686 4.724452682902362 0.7158331323425442 0.2962190784221967 0.051193766701347 0.1234363306283571 0.0313813077886078 0.0793927108250854 0.0780804267632476 +Negative regulation of defense response 8 37 2.2672370988869037 0.0233757456557375 6.924757281553398 32.34466019417476 0.3561607180123788 0.5888237141063734 3.4481835219839927 4.979340389024908 0.80507298525878 0.3146610297306706 0.0860306269033879 1.0 0.0948939281427919 0.0555655068618841 0.0970573207370123 +Positive regulation of cell activation 14 46 2.265680931674825 0.0234709258610261 9.66504854368932 41.58980582524272 -0.0344461667002542 0.6127678592935748 3.990819774604169 3.7854079772897897 0.9017662407322792 0.3302397387818446 0.010258856837804 0.5405770542226526 0.0175330930338341 0.036323739412291 0.0091219588623111 +Regulation of natural killer cell mediated immunity 4 7 2.263529002002885 0.0236030988855959 1.9053398058252424 5.33252427184466 0.1935470825099924 0.4776968923010209 1.19191069217632 1.22419398365008 1.049644639210895 0.3147111439809284 0.0007392957286029 1.0 0.0100519320580488 0.0061570039439817 0.000732082482726 +Long term synaptic potentiation 4 10 2.2633931701922614 0.0236114633979789 3.012135922330097 9.730582524271844 0.4069972937780292 0.4936148854997918 1.5319726166057843 1.7661148877091215 0.9317897164603502 0.2968501206773379 0.0305551934453896 0.0012757726476668 0.0085749794431607 0.0211003003498726 0.0601700233302374 +Regulation of protein localization to cell periphery 11 40 2.260974119488135 0.0237608597270089 8.485436893203884 32.80582524271845 -0.2028012575093506 0.7132607088787091 3.8632298918746537 3.663141663005445 0.5553366011709684 0.2589917776096804 0.0036335926609047 0.0760657989123155 0.2248900268904883 0.0247674911995091 0.0017021800757447 +Cellular response to amyloid beta 2 8 2.2583602851809803 0.0239232066246135 1.8713592233009708 5.91747572815534 0.2206633711995859 0.4678383207618323 1.2867717931543454 1.328545973894273 1.1144604515178314 0.3257294628423651 0.0232832774509756 0.0055832614279084 0.0202898922491691 0.0172025832638257 0.097693310147501 +Response to amyloid beta 2 8 2.2583602851809803 0.0239232066246135 1.8713592233009708 5.91747572815534 0.2206633711995859 0.4678383207618323 1.2867717931543454 1.328545973894273 1.1144604515178314 0.3257294628423651 0.0232832774509756 0.0055832614279084 0.0202898922491691 0.0172025832638257 0.097693310147501 +Lysosomal lumen acidification 5 6 2.258100272922556 0.0239394086367419 1.9077669902912624 4.094660194174757 1.0430284513288333 0.1731957374320673 1.0102570393282595 1.1504623937719378 1.495459416196642 0.2154807950267566 0.0001491979893058 0.0012601973854463 0.0001343549216781 9.549361773523036e-05 4.709357290896995e-06 +Macrophage activation 4 11 2.256555258522769 0.0240358787490433 2.2135922330097086 6.866504854368932 -0.063381422560026 0.4721182263981376 1.4457872208921387 1.8783757746913443 1.04840992449182 0.2953484668101589 0.0030051438102713 0.0007667347448651 0.0004155585626268 0.0116952906397438 0.0081074498059467 +Regulation of phagocytosis 6 21 2.249848694764777 0.0244585516961173 3.3179611650485437 14.968446601941748 0.3209190136413688 0.5915166201342027 2.2957046675959747 2.326811751466005 0.7840787087563237 0.2941325518261171 0.0283612865760576 1.0 0.3404254693467198 0.0195417527514502 0.0042432632735376 +Cardiac septum morphogenesis 4 8 2.247613574412452 0.0246008412350877 2.3155339805825244 5.975728155339806 -0.0276682686733583 0.5118419399844633 1.791959240258615 1.7021953853726592 1.009048346837495 0.3171630722153564 0.0161902722620554 1.0 0.4129317333780675 0.0102355224712358 0.1264250298394598 +Diol metabolic process 3 8 2.247038749084807 0.0246375508049816 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.0682786800017594 0.0756950383436983 0.1432798584585485 0.0557098434243155 0.0062187451165004 +Diol biosynthetic process 3 8 2.247038749084807 0.0246375508049816 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.0467857032007149 0.0619434524836269 0.1180585699575878 0.0379575415698398 0.0027426851014433 +Cellular ion homeostasis 38 106 2.246337351260606 0.0246824078371179 24.48543689320388 87.34708737864078 0.921352068115914 0.4223079442129951 9.212290310790763 8.933596252465952 1.5207794649628892 0.4002972861975121 0.0004433762902237 0.0105180668116997 0.0012172861714086 0.0025406668575644 0.0001392054796729 +Intestinal absorption 3 9 2.2439087607163395 0.0248382723647258 1.7354368932038835 8.587378640776699 0.5171971357504386 0.4141116500991276 1.4895775622567284 1.230532256111229 1.0157231952918233 0.2848944302917708 0.0005664524138943 1.0 0.0088504827764808 0.000366006536683 0.0048470794580564 +Ganglioside metabolic process 3 5 2.2437720842242523 0.0248470694063993 1.7718446601941749 3.2524271844660193 -0.1775376367083389 0.2846388467168437 0.9835459402825288 0.5697631359658722 1.612139414180225 0.2969406455967822 0.0003096916980164 3.066034551708988e-05 5.369271916582234e-06 0.0001991597833083 0.0002434795729679 +Membrane protein proteolysis 6 13 2.2428299962094256 0.0249077793634788 4.138349514563107 11.781553398058252 1.0093176076341577 0.3069750059979975 2.078037067185485 1.3902746514167437 1.0484204695389652 0.2877212872591311 0.2950983042674144 1.0 1.0 0.2511786735203468 0.0027819419936207 +Regulation of leukocyte chemotaxis 5 15 2.242749847548492 0.0249129502208134 4.288834951456311 15.735436893203884 0.121603520762296 0.6602233173792045 2.8123464966854943 2.274896040172022 0.7256331739166136 0.2891116210268169 0.0827445671958278 0.1706778675257841 0.3076603852203092 0.2332121755087385 0.0092437434518958 +Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii 2 5 2.242599368697318 0.0249226609997852 0.8009708737864077 2.279126213592233 0.1909668631601846 0.5076301158126488 0.7433844339420834 0.8018493270518035 1.1946165141997842 0.3310763071132189 0.0070123051135818 0.0023758658868836 0.0088504827764808 0.0050923434600555 0.033288888151673 +Aminoglycan biosynthetic process 6 12 2.2423130331896064 0.0249411480034702 3.0800970873786406 8.300970873786408 0.6387272076133388 0.2830924102482349 1.486473637192798 1.7113836533227735 1.3163721030030058 0.2655273000426038 0.0008611754029795 0.1868885334554594 0.0614247268920475 0.0004698927732866 0.003703553796165 +Antigen processing and presentation of endogenous antigen 2 8 2.240893974164877 0.0250329436729881 2.6529126213592233 6.463592233009709 1.0779744166035472 0.2832041157954688 1.4492771087670022 1.3990755299770097 1.00991421519493 0.2818848392729987 0.0070123051135818 1.0 0.1349531130589082 0.0050923434600555 0.033288888151673 +Antigen processing and presentation of endogenous peptide antigen 2 8 2.240893974164877 0.0250329436729881 2.638349514563106 6.390776699029126 1.097011591019633 0.2766562869747734 1.460743657586565 1.3760123823390067 1.0015631459591094 0.2785574288267012 0.0057231345736884 1.0 0.1265462710440741 0.0041470760753771 0.0276005264132961 +Negative regulation of chemotaxis 4 7 2.2387192582913924 0.0251741886632101 1.8033980582524272 5.155339805825243 -0.0632726487639227 0.4544165494926578 1.311890397237956 0.9952048289283428 1.0730906602614034 0.2945723505476881 0.0030987261931693 1.0 1.0 0.0172025832638257 0.0042587077964903 +Regulation of peptidyl tyrosine phosphorylation 9 34 2.237856775026408 0.0252303965957134 6.378640776699029 27.87135922330097 0.1802199323220069 0.6349333342581757 3.0857219100090787 4.315860914587658 0.7372095149693096 0.2961615496176262 0.1133523751571227 0.453019277017924 0.6943670866160305 0.3398339233179994 0.071689953730443 +Digestive system process 3 14 2.236178383475106 0.025340088602054 2.3640776699029127 11.53883495145631 0.3658311834032546 0.4870903581227657 2.0273544083065516 1.5921368074181557 0.9303375732228962 0.2866214695259424 0.0073200005110444 1.0 0.031373049189738 0.0048864602536943 0.0495301536946375 +Triglyceride metabolic process 3 14 2.234064899086796 0.0254788031554131 3.4805825242718447 10.771844660194176 0.9779567044833 0.270555786798488 1.9834538010888536 2.3392770219831345 1.099054194056709 0.249087443977639 0.0457760313357196 1.0 0.0832345551471358 0.03203241935523 0.0931745181672324 +Sphingosine biosynthetic process 3 5 2.23310591380545 0.0255419607208771 1.91747572815534 4.20873786407767 0.5236437336099039 0.253544361366954 0.9618880285708752 0.5531212048069467 1.4879043514061585 0.274550754534842 0.0101908497095879 0.0290719737908623 0.0563150378970086 0.0081566962170519 7.554554853381166e-05 +Leukocyte mediated immunity 12 59 2.224970928220769 0.0260831898385305 10.5873786407767 48.439320388349515 0.1870678619616392 0.6863169751438244 4.6094706140801085 4.980906020077718 0.7184127170430001 0.2997698808543378 0.0249348983053132 0.5359669486531639 0.016676938082001 0.0812926464798529 0.0081420814083846 +Regulation of t cell mediated cytotoxicity 3 5 2.223863935000564 0.0261576002002175 1.674757281553398 4.135922330097087 0.7411503285093088 0.380666699308082 1.1042915794952284 0.779575982450709 0.9911557427348976 0.2979075232652237 0.0005664524138943 1.0 0.1349531130589082 0.0495157384890535 0.0048470794580564 +Positive regulation of t cell mediated cytotoxicity 3 5 2.223863935000564 0.0261576002002175 1.674757281553398 4.135922330097087 0.7411503285093088 0.380666699308082 1.1042915794952284 0.779575982450709 0.9911557427348976 0.2979075232652237 0.0004243821515525 1.0 0.1265462710440741 0.0435926191526008 0.0036942631899424 +Viral life cycle 26 110 2.223586552767009 0.0261762741247246 19.410194174757283 93.29611650485435 -0.3045293626460413 0.6588462721769274 10.482263936948428 7.880459085859297 0.7518829773930114 0.3155541175306531 7.782450281980006e-05 0.286276536411848 0.0176798363979001 0.0007406380996077 1.7673906628699926e-06 +Digestion 3 15 2.223172384847503 0.0262041781802793 2.6092233009708736 12.58252427184466 0.3381234209976164 0.4686867807613236 2.030163888989284 1.6251916800745976 0.9856074720843446 0.2928277273344397 0.0115921930080417 1.0 0.0398064357050217 0.0078094686864188 0.073496580957787 +Positive regulation of leukocyte migration 5 16 2.2226176080975657 0.0262415958631114 4.097087378640777 15.49757281553398 0.0425334182634543 0.6319024426123137 2.2673904555241178 2.3008006061290747 0.8386767808878971 0.3052449059936994 0.1216860072209825 0.0204019662414969 0.0693457394610891 0.0940672040532474 0.0205399046658008 +Learning 6 23 2.21805634354456 0.0265509909595258 4.589805825242719 18.93446601941747 0.4051379104506336 0.500788863717711 2.588096905713564 2.8673042134954594 0.95936751956091 0.3128033021759736 0.0366493043441931 0.0044455523824174 0.0275216398495969 0.0238750792658836 0.0456420212494776 +Neuron recognition 3 8 2.216741506095075 0.026640760727403 1.9368932038834952 6.189320388349515 0.7447638338644241 0.3705616592284931 1.1064234596616862 1.175429078554095 1.011644937344681 0.2892876339238009 0.0390334633726749 0.1287528218161406 0.2372212797486779 0.0291459656321865 0.0443313868612348 +Regulation of amyloid beta clearance 2 6 2.216559456909426 0.0266532106682988 1.1771844660194175 4.669902912621359 0.8976798268240034 0.3552262661555679 1.056723198112258 1.1917055536064145 0.9128228527254058 0.2874114892997187 0.0020444031671849 0.0479914252810258 0.0921025797166938 0.0014684283121974 0.0105083517934163 +Intracellular sterol transport 3 12 2.2112323798231004 0.0270197492070607 2.0558252427184467 8.070388349514563 0.0137684001556507 0.4375742254192777 1.5763082249183784 1.941472978156742 1.1294096262834266 0.2971146481185643 0.0030987261931693 0.1070183553885475 0.0202898922491691 0.0020400745925255 0.0231565450655555 +Glial cell differentiation 6 46 2.209312267299751 0.027152928520465 9.114077669902912 39.55582524271845 0.0390069906662089 0.6900510842485431 4.944752624574786 4.36438476947918 0.7800237575091793 0.3056622158259627 0.0530371774122747 0.1250660932411784 0.1188989579434368 0.0315515858294127 0.0814040187978287 +Inorganic anion transmembrane transport 8 12 2.208265764227729 0.0272257523946595 3.4101941747572817 8.983009708737864 1.1245392058053427 0.2357455210082705 2.3748669786284156 1.7214248641786654 1.1968417731555627 0.2697184972505711 0.0073200005110444 0.1330370821365251 0.2445730022705269 0.0048864602536943 0.0118390941536887 +Glycosylceramide metabolic process 3 6 2.2075354123455653 0.027276675801539 1.6019417475728157 3.6237864077669903 0.6319353949505291 0.2725232617281626 0.981279191145714 1.1370705133968653 1.4246462713481394 0.2720167900467778 0.0001491979893058 0.0526645480715484 0.0047533286028597 9.549361773523036e-05 0.0013678067399173 +Regulation of biological process involved in symbiotic interaction 2 10 2.20232338734754 0.0276424733096161 2.3179611650485437 8.444174757281553 0.3422289691572587 0.5292477508521571 1.7867820286507592 1.14242547654536 0.8689534085392282 0.2992860869727938 0.1748262021619164 0.1287528218161406 0.2372212797486779 0.4957890007184933 0.151991389222775 +Sodium ion transmembrane transport 8 24 2.201245882232614 0.027718621751158 6.230582524271845 19.861650485436893 0.3704792335969762 0.5741696766418313 3.3118992073574036 3.0326356242212613 0.8979196459015502 0.333569210239074 0.0451515119740483 1.0 1.0 0.0957389801741353 0.0076864406441385 +Membrane invagination 7 17 2.197999883999896 0.0279491142046401 3.6941747572815538 12.16019417475728 0.0473496567323534 0.6174394728479946 2.548303271138053 2.060626721793156 0.8509677037136445 0.3077347987860288 0.087927706130726 0.1747599807978781 0.0538434207197609 0.0671599559498881 0.0104893431674361 +Neutral lipid biosynthetic process 3 8 2.1974798056127924 0.0279861971816066 2.1067961165048543 6.288834951456311 1.1186547336258812 0.1821371148552785 1.2515048910859687 1.3298556757746482 1.2887117600293918 0.213034599641239 0.005642344939503 1.0 0.0274603336438859 0.0037492480554313 0.0394546172777071 +Macromolecule depalmitoylation 1 7 2.195559824749122 0.0281234644766519 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0402937008043179 0.0015075035399645 0.0056684159955205 0.032628233248221 0.1121927202905578 +Regulation of cell junction assembly 10 42 2.189387433983678 0.028568692207936 9.259708737864075 32.94660194174757 -0.3358679076618157 0.5702437255549974 5.326525298900453 4.3036519947638725 0.8636914149992402 0.3111741135209888 0.0035091168343609 0.4279811411777856 0.2961867551178612 0.0194178363725262 0.0208459013040808 +Transforming growth factor beta receptor signaling pathway 6 27 2.187722985981113 0.0286897866735678 6.740291262135922 24.87864077669903 -0.0956469866681699 0.6387114391471552 3.777556089888507 3.581889464108928 0.7561955554325939 0.2952697884954297 0.2106257496636304 1.0 0.3104106640045259 0.15252756528958 0.3389287188110964 +Aorta development 2 10 2.185080500610741 0.0288829446987359 2.308252427184466 6.759708737864078 -0.0774176458664225 0.5304235266925468 1.8287429643020912 1.3840379619847545 0.941147128750552 0.3090353654428162 0.0827445671958278 1.0 0.3076603852203092 0.0630731351339203 0.2791706593827793 +Neural precursor cell proliferation 15 32 2.184486854923913 0.0289264921639695 6.497572815533981 26.52912621359223 0.1279415310538213 0.6708322467655592 3.563228318607038 3.8738137819311658 0.7332829771904489 0.3012792661031277 0.2208975442381702 1.0 0.2107495506364678 0.3637482043753135 0.0661503253872111 +Plasma lipoprotein particle clearance 7 14 2.1834382815785984 0.0290035493922948 2.8033980582524274 11.597087378640778 0.2841472336869506 0.2922439265613805 1.7215617505529983 1.5431625772865891 1.3638326625090953 0.2354738993646769 0.0018071258891623 0.0937235599037543 0.0155240337321844 0.0011814468070448 0.0022125190482932 +Organic hydroxy compound transport 7 40 2.181307380968601 0.029160688863536 7.145631067961165 30.32766990291262 0.3121985122058121 0.5028073494895335 3.2773354290298986 4.4061862301676955 1.0194405540894098 0.3270691777029814 0.0283370053152825 0.4164957533300368 0.2819243430606499 0.0162315127467065 0.1582264017157612 +Cell cell adhesion 47 124 2.18033398979958 0.0292327132951761 23.050970873786408 98.0509708737864 -0.1429190746646203 0.6601701095788187 9.456585727444704 13.145925723777465 0.869400746956233 0.3243063932634235 0.0004461415884791 1.0 0.5298070105758321 0.0297206715721578 1.6923012410264684e-05 +Regulation of mononuclear cell migration 5 17 2.1753664353471853 0.0296026676592882 4.548543689320389 16.800970873786408 -0.0451470857329185 0.6235913245378032 2.5976226650972936 2.65933034660148 0.8401157368959713 0.2924888202464074 0.0305551934453896 0.0195557545343205 0.0666692325567911 0.0211003003498726 0.0185344065780108 +Embryonic digit morphogenesis 2 6 2.17509232931046 0.0296231981729964 1.4684466019417477 6.54126213592233 0.5989020645284063 0.4429704011231127 1.569266266788618 1.559731853735315 0.934963282113679 0.3039103680308826 0.1099537277713604 1.0 0.3404254693467198 0.0846608217542885 0.3464086329062056 +Phospholipid transport 6 20 2.1730052752086597 0.0297799202546784 4.038834951456311 13.844660194174756 0.8595089147672731 0.22382450694892 1.931709490395295 2.5542930986961077 1.4491821424024287 0.2459407475876757 0.0024132782296447 0.2222355866483168 0.0128487417044244 0.0074685925596388 0.0109403402937121 +Positive regulation of chemotaxis 6 19 2.169529555453951 0.0300425030079218 4.817961165048544 17.016990291262136 -0.0747669348721738 0.5950152021464032 2.720538160362209 2.4538858959203873 0.8730469970494442 0.3017299719942363 0.0486569865865319 0.2222355866483168 0.3896854720293997 0.0341229578056568 0.0109403402937121 +Amyloid precursor protein biosynthetic process 2 5 2.169457737062527 0.0300479496424426 1.529126213592233 4.050970873786408 0.5724883308647799 0.4003128139433519 1.0007891127244537 1.1319816926742772 1.117383900072293 0.3129811194531851 0.0014601836592373 0.0432957136582515 0.0031504918831051 0.0010464818333657 0.0076273123324074 +Amyloid beta metabolic process 2 15 2.1684982474459416 0.0301207978201276 3.6771844660194177 13.24514563106796 0.6724101183977472 0.416551332754989 1.8088680779022668 1.8049556184618043 1.0101286409291856 0.3102485572243311 0.0986900198440846 0.1828652209005429 0.0588586045542952 0.0756846958642696 0.3194770492897782 +Nervous system process 37 123 2.1661657115443744 0.030298526275762 23.060679611650485 100.46844660194176 0.466210961761844 0.5050785047376438 7.1617042179301365 12.55034423055404 1.1784062094355452 0.368401069133876 0.0017201543032802 0.000145551864262 0.0005393819255308 0.0009239154417879 0.0014948262995437 +Neuron death 15 79 2.163459076153865 0.0305058880587252 14.20388349514563 73.25242718446601 0.8007457732231772 0.4829929240620625 5.370919943079612 7.537889337352574 0.9625497526284538 0.3667297831171348 0.0776482963921504 0.0938642261720824 0.0615495803785245 0.041648628319696 0.0705706835163868 +Zymogen activation 2 11 2.1615075935732726 0.0306561510154812 1.7402912621359223 8.048543689320388 0.2681171507749159 0.4816463680963982 1.616969451297242 1.3644490390373976 0.9797969023910962 0.2836022963171947 0.0505053913877401 0.0100088432903632 0.0031841845740684 0.0379489226270714 0.188221571487594 +Import into cell 15 38 2.1613458667634493 0.0306686323519871 8.441747572815533 26.468446601941743 0.278986899549401 0.5712036628248293 4.717145431684204 4.63434566286081 0.9247855241772484 0.3264760057770247 0.005648810581868 1.0 0.6211264656767345 0.0337698983302116 0.0010334461262557 +Amyloid beta formation 2 13 2.1556785198115977 0.0311087765859088 3.4466019417475726 11.150485436893204 0.7369482521385301 0.3719348072839057 1.602353580483856 1.6769930201386472 1.043709172018907 0.2948415726419107 0.063420859184832 0.1541506060207377 0.0420348553288257 0.0479498850625808 0.2263767375285751 +Neuropeptide signaling pathway 2 6 2.1534616696127973 0.0312824134073213 1.0849514563106797 3.1189320388349513 -0.0985724577330871 0.419688363037091 0.853358156505566 0.8690642357540188 1.297775726458379 0.3194504309420363 0.0045876876261238 1.0 0.1180585699575878 0.0033170374819039 0.0224777557227792 +Cell chemotaxis 13 41 2.1510898529302973 0.0314691082628957 9.135922330097088 37.060679611650485 -0.0784030605852576 0.6324652441331359 4.405531703007072 4.1435067372718635 0.8456116765533065 0.3122963338427361 0.0283370053152825 0.4164957533300368 0.6529810462024153 0.1233346492847209 0.0163296761215923 +Response to copper ion 3 9 2.148805169156629 0.0316498474770499 2.1237864077669903 6.650485436893204 -0.2406927634580937 0.4658860369394658 1.241169677348988 1.3861922271332412 1.0686867810452498 0.3023504783512977 0.0181910910024147 0.0046633751497463 0.0010099703116007 0.0133829456596615 0.0168879338153791 +Entry of bacterium into host cell 1 5 2.147953175153193 0.0317174754508875 1.3106796116504855 3.8276699029126218 0.2836426884969484 0.4711320987549692 0.9682245408111568 0.8656954148140601 1.0435307337239907 0.3123167717473686 0.1748212797296205 0.0338360956076009 0.0653907127050202 0.1571881112173651 0.0418361746391697 +Glycerophospholipid catabolic process 2 10 2.147635178570941 0.0317427485204486 2.216019417475728 7.563106796116505 0.8419758607208171 0.2558936783676348 1.405411068501889 1.391164232085279 1.2384126210044872 0.2497846504551273 0.008459922663953 1.0 0.0100519320580488 0.0061570039439817 0.0395358442373242 +Synaptic vesicle exocytosis 10 18 2.1451146264220653 0.0319436832756414 4.618932038834951 16.711165048543688 0.2860328341556032 0.6404005401290624 2.47961217317585 2.1079073508917427 0.6807802949393439 0.2890621858043471 0.8282728933132675 1.0 0.4620800234731917 0.7915335109512663 0.0116770517604269 +Cardiac septum development 4 15 2.1407244195020967 0.032296268064994 4.37378640776699 12.021844660194176 -0.249514902723942 0.5691557187351993 2.985578968913915 2.2752378506082436 0.8491564007523815 0.3060454816696332 0.0682549083787072 1.0 0.5440657264544094 0.0457838139336303 0.355900849926696 +Regulation of gliogenesis 3 17 2.140193763840428 0.0323391109448685 2.5776699029126213 12.766990291262136 0.4275984781816435 0.4940387299474685 2.0387713813482975 2.058389810399436 0.9188590751221472 0.30630744557224 0.0457760313357196 1.0 0.0832345551471358 0.03203241935523 0.0931745181672324 +Response to ph 3 8 2.1327077058524195 0.0329487113895357 1.7621359223300972 5.140776699029126 0.3480088533355521 0.3739523760080299 1.2528504590681426 1.153124661134805 1.2011912824917792 0.2945428652003891 0.0018071258891623 0.0042324529563037 0.0155240337321844 0.0011814468070448 0.0142025885279179 +Ensheathment of neurons 12 31 2.1289155663412824 0.0332612466536612 7.109223300970874 25.317961165048544 0.4295341143396002 0.5630321678871352 3.545161118750975 3.535996271146197 0.857834731365342 0.3150461050621543 0.0899977952309678 0.0691107257825923 0.2072288126229632 0.0613062198602933 0.1338805748544562 +Glucose import 4 15 2.119584159196792 0.0340411295323814 3.4563106796116503 11.364077669902912 0.3176045676169922 0.5089134846135845 1.8514056534885703 2.196305563870774 0.9183417404528994 0.3012736273802708 0.1216860072209825 1.0 0.3530974878629287 0.0940672040532474 0.0651237881613715 +Membrane protein ectodomain proteolysis 5 11 2.1192374452452176 0.034070405228374 3.2815533980582523 9.42233009708738 0.914660566901433 0.3175120830558543 1.6482852268027584 1.2623319489295757 0.9882621955102872 0.2679281534911034 0.2044070346705839 1.0 1.0 0.1713585638073601 0.0032807303767948 +Proteoglycan biosynthetic process 6 12 2.11801179331318 0.0341740689171889 2.6432038834951457 6.677184466019417 0.8965384350791714 0.2873226841395866 1.6239641738792057 1.992745053805788 1.1569297556833695 0.2755887487741971 0.0003122463304368 1.0 0.2872333566147377 0.000167417985794 0.0012367549633919 +Positive regulation of autophagy 6 34 2.117818906611825 0.0341904074928187 7.036407766990291 30.483009708737864 0.6693528554580194 0.4628135853102879 3.235293043364778 5.784747493453153 0.9361869896860724 0.333658419297932 0.5882790470433267 0.4251307382490726 0.292624050209727 0.5099520664807343 0.2996131458018038 +Response to hepatocyte growth factor 2 9 2.1173086182614123 0.0342336639490852 1.83252427184466 5.682038834951456 0.22147406836211 0.5067944222688716 1.3469168089334904 1.8521485079710065 1.0288209560233612 0.3181783420506056 0.0070123051135818 0.0711332726649859 0.0088504827764808 0.0050923434600555 0.033288888151673 +Transepithelial transport 6 7 2.115915488724396 0.0343519958738256 1.6553398058252426 4.774271844660194 0.6732735902855568 0.3468688130957016 1.1752486335033188 1.0771313051019258 1.1029852758785914 0.2818815040837556 0.0100699756610546 1.0 0.1515272625734178 0.0621585272883563 0.046330877355434 +Regulation of response to biotic stimulus 11 75 2.115139318897019 0.0344180749390115 14.20388349514563 65.80582524271844 0.169421492657069 0.7394499822244347 5.9534753223315775 7.172030697018415 0.6318689594517273 0.297582268231637 0.078952575413169 1.0 0.1149430460895222 0.1855120677088796 0.0856244339288375 +Dendrite morphogenesis 8 35 2.1149218683342617 0.0344366070132824 6.922330097087379 29.33495145631068 0.0392542367033255 0.6458754200465586 4.7683000988594975 4.1552916021158355 0.7624317858280742 0.2897540445961646 0.3290849849597505 0.410668613679594 0.2747845331601694 0.2583585694619627 0.0746496231499551 +Positive regulation of nervous system development 12 50 2.1144848164019354 0.0344738802512429 9.114077669902912 40.93446601941748 0.0707478234609245 0.7143448967467 5.857042551516769 4.481144580762786 0.6285439247773889 0.2777025287698339 0.0577893909690714 1.0 0.4375150159471063 0.0791591001065906 0.0704491755328268 +Cell volume homeostasis 6 8 2.114216246523702 0.0344968018743849 2.1723300970873787 5.337378640776699 0.2512935818542527 0.4530452279045648 1.556979714955685 1.7832175899581115 1.0955975152904005 0.3216113819420377 0.0760398405796242 0.0802348466038066 0.1515272625734178 0.0621585272883563 0.046330877355434 +Platelet derived growth factor receptor signaling pathway 4 12 2.1128167200044907 0.0346164580259011 2.1480582524271843 8.762135922330097 0.1166335759993331 0.644523758102582 1.9396028811105843 1.875162983458992 0.6908623357609962 0.2665500176607754 0.2445684315621151 1.0 1.0 0.2064377407436189 0.0873197005539923 +Retrograde transport endosome to golgi 12 36 2.1109858318644927 0.0347735296776026 8.844660194174757 34.00485436893204 0.6408100896550543 0.5235396612667444 4.365036019054001 3.8497226893137166 0.9745365654790862 0.3516062635557995 0.1871814364624166 0.3361355940595682 0.1897338295109766 0.1403572550086468 0.018640278593319 +Vascular process in circulatory system 10 39 2.1101372029343266 0.0348465396336075 8.218446601941748 31.361650485436893 0.5302527350177477 0.4259259059419516 3.6564678051714665 4.365329555745678 1.181021277396986 0.3310828049268227 0.0008334102743841 0.4222664170554933 0.0219950308691545 0.0014236280399173 0.0026925096908203 +Carbohydrate transmembrane transport 5 18 2.109463572631552 0.0349045871151363 4.012135922330097 14.080097087378642 0.1345934828511105 0.552100805518534 2.094224211847023 2.682357315361447 0.8764783529730497 0.2919122713750917 0.2283839235532806 1.0 0.4461675288226883 0.1820516573570916 0.0739124968095968 +Cytokine production 28 119 2.108399190452925 0.0349964744145661 18.97087378640777 96.13106796116504 0.0824735848580317 0.7508975178485808 7.48909409104055 11.178920255675855 0.680456448776925 0.3062861740716413 0.0083331699966868 0.2194362352690881 0.0978323244448722 0.0290196546140146 0.001371711483292 +Memory 3 11 2.104218776503795 0.035359367381651 2.405339805825242 8.388349514563107 -0.0748247495242427 0.5692325656366838 1.5821426515864156 1.7093859097696993 0.8297311978516596 0.280650564703965 0.0751884104816538 0.0337662417977069 0.018985818871393 0.053649406266927 0.1563988211713662 +Negative regulation of cytokine production 7 34 2.101533774834329 0.0355941363667782 5.587378640776699 27.0995145631068 0.3493721415420291 0.6285719352614387 3.172184314104491 4.02869558466082 0.7014733327898341 0.3026625991309797 0.5697630540552265 1.0 0.6529810462024153 0.4917785346424383 0.1582264017157612 +Cellular response to estradiol stimulus 3 7 2.100060093996672 0.03572355515904 1.1213592233009708 4.177184466019417 0.7109195420244362 0.4441673256339644 0.9974871812629288 1.2188502599841993 0.9080939600374738 0.309991306495748 0.1184088205118859 1.0 1.0 0.4160065505344545 0.0198699646710478 +Negative regulation of developmental growth 4 14 2.099337949329714 0.0357871203633892 2.6067961165048543 10.118932038834952 0.4177621670448362 0.5151603515616955 2.0822300468824904 1.7258544598953018 0.8590834947670382 0.302034516552393 0.1793772759069759 0.2336798458054532 0.4072036678679048 0.1411134338084059 0.1193828224832026 +Neuron maturation 1 6 2.098287273806415 0.035879776038729 1.6966019417475728 5.737864077669903 0.3884050692002241 0.3270287101850628 1.1310653568868725 1.188220216330287 1.2760249805885358 0.2674215567147113 0.146042597995461 0.0065792573185243 0.0237627189197599 0.1211421538065826 0.3433653057642475 +Receptor recycling 2 9 2.097339262805965 0.0359635535514117 1.83252427184466 7.075242718446602 0.2017018942761934 0.4536082228606722 1.6905248328776263 1.154000508707628 1.0635166063679875 0.2938337757297349 0.0322196793383797 1.0 0.0019068669696529 0.0239571113561098 0.1292339698967795 +Basement membrane organization 3 9 2.082961780161456 0.037254707481471 2.2645631067961167 5.400485436893204 -0.278184580989995 0.5743466516087928 1.4830454606149273 1.6031824409930098 0.8421059852254648 0.3008346693238882 0.1008235479946778 1.0 0.1758008751515455 0.0828772873031817 0.0142025885279179 +Amino acid transport 9 24 2.0809307880375827 0.0374402415900976 7.771844660194175 19.75 0.8410032854505353 0.3449280742441291 4.117377746800764 3.003739578643708 1.287399790463736 0.3206698223659758 0.0107340621172042 1.0 0.4876012483283494 0.0062576945030878 0.0179003220004013 +Osteoclast differentiation 5 14 2.080298109718248 0.0374981980808217 3.3567961165048543 10.419902912621358 -0.2065192558639911 0.557799022178809 2.186982100064913 1.6118167974780178 0.8796946296005602 0.3082817729760667 0.0019601597157597 1.0 0.0803922289273931 0.0010882828125207 0.0300212330028383 +Positive regulation of exocytosis 7 19 2.0750214551038866 0.0379845463592425 4.851941747572815 15.635922330097088 -0.0489330116866824 0.6595888829829153 3.377527261825379 2.269140993489897 0.7216650970542056 0.2925829677358729 0.3648464431627546 1.0 0.3655284832956332 0.3140672800286707 0.007013421835749 +Cell adhesion mediated by integrin 4 10 2.067267085897309 0.038708993881962 1.9757281553398056 6.682038834951456 -0.0050385565942661 0.5033340977925423 1.5546339137276437 2.1482365128161987 0.9546905404384666 0.2919374090244441 0.3451343629390367 1.0 1.0 0.2961580697833918 0.0651237881613715 +Cell morphogenesis involved in neuron differentiation 26 113 2.066420509267945 0.0387887910348461 19.59223300970874 91.78155339805824 0.0633940435481119 0.7404601122693133 9.411763856852913 11.295279945325175 0.755341800166473 0.30636858572397 0.0184225633411235 0.5314988326551623 0.2646670816945575 0.0279739905883354 0.0158697387329274 +Regulation of exocytosis 17 46 2.0640664045708186 0.0390114207444469 8.864077669902912 39.16019417475728 0.1036096249992311 0.7254597910393834 4.068702576271896 4.34423711125452 0.6304811118238788 0.2835648818538584 0.8336118134806658 1.0 0.6821824234140106 0.7822764725934116 0.0045904522439485 +Negative regulation of neuron projection development 10 24 2.056017960497279 0.0397807850329299 4.944174757281553 19.932038834951456 0.8070712719008988 0.4165241941447024 2.3357271686464363 2.7475042016888107 0.8484003015222881 0.3001902418041021 0.176339660272296 1.0 0.5440657264544094 0.1316996895499912 0.0160968519491793 +Response to mitochondrial depolarisation 1 9 2.05318789472686 0.0400543579950265 2.4635922330097086 7.439320388349515 0.5975404704267634 0.4417505348750569 1.531588016779825 1.096644274293901 0.8946129564546079 0.2998729921389195 0.0682786800017594 0.0756950383436983 0.1432798584585485 0.0557098434243155 0.1801322612125274 +Membrane raft organization 4 10 2.052589514168265 0.0401124053774888 2.533980582524272 8.924757281553399 0.544342121241576 0.3623081632411893 1.688427394821621 0.9935074131191508 1.097645488795839 0.2730349650970456 0.0009463420108467 0.0802348466038066 0.1515272625734178 0.0621585272883563 0.0009961752813945 +Leukocyte chemotaxis 9 27 2.051436477520626 0.0402244597768568 7.004854368932039 27.12621359223301 -0.0186974105931124 0.6948953376593175 3.940698243800774 2.645493004324857 0.6892497455842508 0.2851334438258616 0.1353775558521509 0.3024216363859021 0.5071521873221705 0.5291696351238756 0.0243632047080926 +Cytokine production involved in inflammatory response 1 8 2.049526519573122 0.0404106573721789 1.6844660194174756 6.915048543689321 0.5526695518877155 0.4572127495678942 1.5208746385948606 1.410799796429201 0.9262620288568464 0.3010153054171438 0.1274683960400928 0.1070183553885475 0.0202898922491691 0.1053546389470493 0.307235981321659 +Transcytosis 2 10 2.0491599083767595 0.0404464809665501 2.6893203883495147 7.381067961165049 -0.0963525316297316 0.5283427390922439 1.9769503149641223 1.1774296611822574 0.947888091156137 0.3079267096508385 0.0057231345736884 0.066549445548378 0.0077184558590264 0.0041470760753771 0.0276005264132961 +Defense response to gram positive bacterium 1 5 2.0475970430043944 0.0405994993359095 1.7427184466019416 4.492718446601942 0.047001436601032 0.591255631744899 1.20750902561483 0.9070625738948188 0.8367827300037257 0.3041101438807402 0.0923316485580286 1.0 0.1677870330809631 0.0757571260003459 0.2341882727805034 +Vacuolar localization 6 20 2.0419545425702923 0.0411560406636068 4.296116504854369 16.303398058252426 0.3731056291223962 0.5807241341119216 3.025728583689353 3.010932846899764 0.7579993017458981 0.3016155436945166 0.7673521509156922 1.0 0.4014202890149608 0.726859415108312 0.1125319425951153 +Nerve development 4 11 2.0412783172445885 0.0412231710119377 1.5679611650485437 7.463592233009709 0.9323166733630548 0.322181793723066 1.371606215406715 1.1303984643014222 0.9327393846140116 0.2711478939504144 0.1157633766244994 1.0 0.3467918934582977 0.0893115916137597 0.0601700233302374 +Negative regulation of growth 7 36 2.040328386584928 0.0413176293242727 5.817961165048544 30.390776699029125 0.1801984393176988 0.6389493459236367 3.663433547604644 3.7005919729330703 0.7775873943572781 0.3097525958014036 0.2919903684517038 0.1382881174102461 0.3665925032588032 0.2182630701805741 0.3163953022874241 +Synapse assembly 6 24 2.0396632285392284 0.0413838797528096 5.468446601941747 17.45873786407767 -0.3282763699124831 0.545572046602979 2.899861817023056 3.166227481604147 0.8429479411025542 0.2967774114004993 0.0599411916866013 0.3194831905047319 0.1724639155075248 0.039939538046367 0.0830471761800712 +Carbohydrate transport 5 21 2.03709568123573 0.0416404546139936 4.725728155339806 17.317961165048544 0.1347863377600586 0.585526017516962 2.279077100704329 2.835860465716908 0.8210424195743269 0.2894489471893008 0.3241427499496668 1.0 0.5119234098565739 0.2645177746775517 0.148254160067468 +Myotube differentiation 5 16 2.0350355007742977 0.041847301020188 3.917475728155339 15.429611650485436 0.7362493461217297 0.4654023872843359 2.2583148277114424 1.8108081242298664 0.8490361901889097 0.3242501735929494 0.0751884104816538 0.2523879312119707 0.4353012614103685 0.4184251288308143 0.0649170986110887 +Glycosyl compound catabolic process 5 11 2.03314458211975 0.042037917989258 3.216019417475728 9.74271844660194 -0.2866012386822237 0.2471021044870933 1.8641835401772064 0.9067280280460008 1.4904201092322935 0.2120144867281597 3.3253048315786296e-05 0.0060718409625537 2.722163485266692e-06 1.734109635655837e-05 0.0007997701188881 +Connective tissue development 8 28 2.029687690215577 0.0423882949535727 6.759708737864078 24.91747572815534 0.897701915164713 0.400129048313066 2.7453452066208146 3.8608044632925673 0.8993390896039578 0.3237981500894625 0.2658618425221968 1.0 0.3491903780040699 0.1968043466135108 0.4269877292365965 +Positive regulation of regulated secretory pathway 2 6 2.028961447520285 0.0424622172034094 1.75 5.075242718446602 -0.0873412593365057 0.4894396427643672 1.261115625689898 1.239193556004507 0.9961975074951256 0.3010295207633872 0.4535801711975754 1.0 0.191600110602388 0.4160065505344545 0.0879711233989737 +Regulation of triglyceride metabolic process 3 5 2.028768822786297 0.0424818422315289 1.3228155339805825 3.3592233009708736 1.131256217881094 0.2247764815137437 0.8562527499503464 1.0621865059572388 1.262109616098846 0.2273835312839994 0.0181910910024147 1.0 0.0170518298819148 0.0133829456596615 0.0168879338153791 +Response to manganese ion 3 7 2.0265007047329933 0.0427135005826633 1.6237864077669903 4.803398058252427 0.1657661936697436 0.3714959689201358 1.1370705133968653 0.8633239594876049 1.253188844081787 0.2928478007224994 0.0467857032007149 0.0619434524836269 0.0066572828402184 0.0379575415698398 0.0027426851014433 +Appendage development 4 18 2.0223124628172897 0.0431440819178521 3.283980582524272 15.37621359223301 0.1480909574057644 0.5969421392568955 2.39526954512383 3.7053775187314058 0.7995041457403814 0.2918586249779653 0.24536738460704 0.4584356988059179 0.335158199257754 0.1802028808367961 0.7242744689694 +Positive regulation of protein localization to membrane 10 33 2.021834364243134 0.0431934663465141 6.842233009708738 28.00242718446602 0.1550235383369629 0.7260641052542587 2.930731520743132 3.909472431326232 0.6015798181817977 0.2778032269137012 0.0626445912019631 0.3228460923172884 0.5351022899588459 0.1232731888960198 0.0368737838171199 +Regulation of synapse assembly 4 11 2.0211553028312386 0.0432636910108916 2.5606796116504853 7.859223300970874 -0.0792788242373662 0.5395185567400329 1.7274785273339432 1.5932464806786577 0.9385185942947613 0.3087264731082229 0.0262642634944141 0.1868885334554594 0.0614247268920475 0.0180565405233996 0.0509303706641057 +Positive regulation of leukocyte degranulation 2 5 2.0154716225199074 0.0438552565102621 1.5485436893203883 4.104368932038835 -0.0678844104640752 0.4557274155100288 1.1016637089887702 1.0866713849368663 1.100796270919578 0.3060033725800987 0.3002039676429321 1.0 0.1180585699575878 0.2721697661507766 0.0224777557227792 +Tumor necrosis factor superfamily cytokine production 6 23 2.015062954549513 0.0438980531917632 4.737864077669903 18.82766990291262 -0.1176808859552237 0.5397692657842946 2.2618025505427357 2.5773304861280857 0.8990343722058798 0.2969480078341584 0.121144668130456 0.046072228335376 0.1454623761357323 0.2385176558358965 0.0520396071305295 +Positive regulation of tumor necrosis factor superfamily cytokine production 3 16 2.0137739286987424 0.0440332741391262 3.313106796116505 13.021844660194176 -0.0749323239771777 0.5255818975341178 2.0112603058084755 1.6301195665080102 0.950576324381458 0.3044652530020598 0.1216860072209825 0.0204019662414969 0.0693457394610891 0.2961580697833918 0.1723337140806459 +Activated t cell proliferation 2 6 2.013603912965786 0.0440511352914945 1.587378640776699 5.587378640776699 0.4688890095939692 0.5024755089693376 1.250101324953533 1.06790600034048 0.8869207895451094 0.3068875467389154 0.0760398405796242 1.0 1.0 0.0621585272883563 0.046330877355434 +Positive regulation of endocytosis 7 25 2.0120226206274494 0.0442175525215655 4.560679611650485 19.640776699029125 0.3893750024867851 0.549188937881148 2.507020729109805 3.151065065533248 0.827344309517849 0.2971633472740571 0.0258855535741053 0.2633971592089756 0.1194965359594502 0.1881433143308717 0.0096996341230332 +Regulation of monocyte chemotaxis 2 5 2.010946788616151 0.0443310775174798 1.7985436893203883 4.563106796116505 0.2419118279045856 0.5315408384178865 1.2640272423687977 0.9943520397152368 0.9572879176135618 0.3175690600743351 0.0140138067082515 0.0338360956076009 0.0653907127050202 0.0112385866308786 0.0034179138545613 +Multivesicular body sorting pathway 6 11 2.0047339367581527 0.0449914984232073 3.6359223300970873 9.78640776699029 -0.1810336664398455 0.5162255419819344 2.4322810568679056 2.708850956333514 0.9408987448883844 0.3036130638017798 0.2748990391139122 1.0 1.0 0.2332121755087385 0.1102038070082231 +Endosome transport via multivesicular body sorting pathway 6 11 2.0047339367581527 0.0449914984232073 3.6359223300970873 9.771844660194176 -0.1823654481708407 0.5154199047141006 2.436269405325817 2.7049726763413044 0.9417366796599927 0.303713653465761 0.2044070346705839 1.0 1.0 0.1713585638073601 0.0608861307148366 +Golgi to vacuole transport 2 8 2.0014287559774564 0.0453462043348906 2.1990291262135924 6.684466019417476 -0.1721194290132491 0.5176214279350251 1.5293881729690744 1.066912547853689 0.9858058434549826 0.3169991723772594 0.084064100232846 1.0 0.1596960736798767 0.0688460117016781 0.053660443290246 +Response to transforming growth factor beta 7 37 2.0001375410618567 0.0454854139892411 8.410194174757281 32.536407766990294 -0.094101059672419 0.6394779055878194 4.225924723432897 4.710671082480533 0.7756039910569711 0.2958728495226654 0.3885594529895906 1.0 0.4276292777269929 0.3004301267885648 0.4497105929007091 +Autophagosome organization 12 33 1.9995965787420316 0.0455438436810833 7.182038834951456 26.570388349514563 0.1959965762708488 0.6424664291527115 3.9411160656788633 4.6942845691516135 0.7864117658771023 0.3125757506363847 0.244207867391811 1.0 1.0 0.390070601507347 0.0358455322365338 +Nucleotide transport 5 15 1.9989173271843 0.0456172996426726 6.189320388349515 13.405339805825244 1.3859091987706234 0.2148450774807873 3.399469193898354 2.266957807297256 1.34942986946681 0.2785977875693559 0.0049092326538637 1.0 1.0 0.1292409073430241 0.0073870683046854 +Blood vessel endothelial cell migration 7 27 1.9979489999581208 0.0457221895484227 4.536407766990291 22.449029126213592 0.7681724367497832 0.3963490094539818 2.4704338498615206 2.406468634828595 1.0319905271466427 0.3120666413936225 0.0114817371357263 1.0 1.0 0.0067097031977977 0.0193850216691963 +Neutrophil migration 4 15 1.992940044384697 0.0462680127124957 3.9854368932038833 14.512135922330096 0.1269410215729747 0.6697286325425675 2.633757984288598 1.4934641755532814 0.6743180167806408 0.2758469704910942 0.2647856458513017 1.0 1.0 0.5955662992954859 0.0317140083874149 +Mitophagy 3 17 1.9913290490293287 0.0464447238560887 4.174757281553398 14.737864077669904 0.7026339988268726 0.4220360300693995 2.5842209186951752 2.0501535109396865 0.9566781806577936 0.318538155650451 0.2044070346705839 0.141543756104335 0.2590666885683055 0.1713585638073601 0.0608861307148366 +Pinocytosis 2 7 1.9911802685246665 0.0464610723076774 1.8713592233009708 7.33252427184466 0.5840579949486326 0.3745201042297812 1.4960968950914608 1.2320991783672317 1.0871891924456092 0.2933375341256155 0.084064100232846 0.0847528009868792 0.0126574737404708 0.0688460117016781 0.053660443290246 +Positive regulation of b cell proliferation 2 5 1.9893289219187609 0.0466649093661493 1.220873786407767 3.754854368932039 0.4952339660039194 0.414488467152393 0.8574353345892436 0.8393251612839969 1.1392298980155808 0.3110872661020623 0.0100699756610546 1.0 0.0113213926532688 0.0621585272883563 0.046330877355434 +Cellular carbohydrate metabolic process 15 73 1.9883422340394925 0.0467738528277561 12.298543689320388 60.53398058252427 -0.0198217634236293 0.5474782336568482 5.253819490464295 6.177496797185298 1.0012857082474305 0.3337612932793398 0.0032657422523174 0.2170623616565413 0.0283208578149016 0.0038858990698922 0.0125975887228785 +Regulation of platelet derived growth factor receptor signaling pathway 2 6 1.987993124611484 0.0468124503746374 1.3990147783251232 3.251231527093596 -0.1781565980011137 0.558471899847691 1.0187401737702908 1.2017786328420872 0.9944214655407514 0.3259840779299563 0.3555827334248693 1.0 1.0 0.3236592382947187 0.1801322612125274 +Regulation of regulated secretory pathway 9 21 1.9869801270848235 0.0469245991444944 5.135922330097087 19.024271844660195 0.5532028818011353 0.482650154445206 2.517120190261048 2.8085156919839167 0.8466655843360735 0.3050640843792452 0.8545030385529222 1.0 0.4925597827158772 0.8201241756611954 0.0520396071305295 +Regulation of peptidase activity 15 91 1.9822629784412729 0.0474498152530422 17.567961165048544 78.76456310679612 0.2681055370567821 0.6519293611165848 6.220288033667961 7.048060158198876 0.8199709838080707 0.3419859398793775 0.0187607037560061 0.0967862116473507 0.0207490083431537 0.008095305808829 0.0774921093266688 +Substrate dependent cell migration cell extension 1 5 1.9792040173555137 0.0477930408043705 1.8155339805825244 3.978155339805826 -0.1308291345820093 0.5523649123802062 1.19868514385056 1.0154192281413887 0.9433949764827182 0.3182538260559882 0.0183539828864478 1.0 1.0 0.0147480216610697 0.0540238893245918 +Neutrophil chemotaxis 4 12 1.97827915441412 0.0478972234091279 3.7354368932038833 12.029126213592232 0.126500981349104 0.6965845074264393 2.7939613373766283 1.20037462339776 0.6642847589220878 0.2867326917339619 0.1748262021619164 1.0 1.0 0.4957890007184933 0.0101939997718642 +Synaptic vesicle priming 4 5 1.971194138058884 0.048701674171304 1.0849514563106797 3.1844660194174756 0.0755713739453349 0.5281836204259941 0.9578833601353 1.061209904984661 1.0910263621026473 0.3164301016581804 0.3555827334248693 1.0 0.1432798584585485 0.3236592382947187 0.0062187451165004 +Negative regulation of cell projection organization 9 34 1.971041901226559 0.0487190832692863 6.281553398058253 29.016990291262136 0.4941593335808462 0.5349350626710885 3.4357274091046452 3.2317001852406393 0.8729841284160588 0.3226134265261706 0.2057989022494195 1.0 0.6759110170121503 0.148729549223989 0.0545502657151787 +Cell killing 7 23 1.9696121918633367 0.0488828332927413 4.980582524271845 19.76941747572815 -0.3950147221290557 0.4789316173282891 2.7323327723965236 1.9774791863658472 1.053232503854796 0.3163253937429116 0.0050448117271522 0.2523879312119707 0.018985818871393 0.053649406266927 0.0072152122103698 +Heterotypic cell cell adhesion 7 12 1.9690398475790043 0.0489485154235349 3.283980582524272 9.87135922330097 -0.1157334657886514 0.491655693009559 2.2510915754754093 1.39536510762595 1.0517413970520408 0.3057914387152954 0.0073200005110444 1.0 1.0 0.5079876539292768 4.992667659276478e-05 +Regulation of metallopeptidase activity 1 5 1.9647125098552745 0.0494475212249949 1.1237864077669903 3.3106796116504853 -0.0060651105555091 0.6037729146711031 0.968793280528811 0.619726313122614 0.9066188864895364 0.3211850264984928 0.0341781603031309 1.0 0.1008375048293403 0.0276231155809849 0.0964811850177102 +Peptidyl tyrosine modification 11 49 1.9639261003675677 0.0495386625376443 8.70388349514563 37.73543689320388 -0.0239454267802142 0.6861916771215885 4.618418641018608 5.785435895284358 0.6551498843976254 0.2777474877708394 0.1469724180673337 0.6124177022714303 0.8446675734226833 0.4907559923624083 0.2160484329940452 +Regulation of jnk cascade 6 21 1.962898027888304 0.0496580239841171 3.745145631067961 12.730582524271844 0.0342722637181126 0.5856074037040684 2.335999552831812 2.800439745372428 0.865405433051665 0.3027772361459041 0.3909340927467986 0.3361355940595682 0.552858073626208 0.5990875991193605 0.1068343844982337 +Collagen catabolic process 2 5 1.960810272833469 0.0499011592510041 1.2233009708737863 2.6820388349514563 -0.38176458327297 0.467635042954794 0.7874259260579268 0.8115475558370256 1.1646709697932778 0.3198741910958743 0.0020444031671849 0.0010343090391069 9.839858993160587e-05 0.0014684283121974 0.0009048869233579 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..16d8a2fea1335fb5f4dde7390656da33522495be --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 6702, + "title": "Average number of proteins per term", + "value": 21.67397791703969 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f4918a53b3d1eed152c8c9c293db90c087bc1b57 --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..cd7295d35581ec432d801cb598e62252a319f9f2 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,2370 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Sphingolipid metabolic process 0.8282404665798735 3.961437612640996 7.449984887153427e-05 0.3930546875992525 0.2249415445643765 39 Q92485,P27544,Q9NWW5,P04062,P07602,P06280,P17900,P16278,P50897,Q9NRA0,P06865,Q92484,Q99805,Q13510,P07686,O15269,Q06136,Q96G23,Q9H2C2,Q16739,Q8NCC3,Q99519,O60512 23 +Entry into host 0.8127215615570306 3.936663064296303 8.262248463064559e-05 0.4252147399793514 0.2249415445643765 43 P07711,P07858,Q9BTY2,P00533,Q14118,Q8WTV0,Q9Y624,P17301,P35613,P06756,Q96J02,Q14108,P01130,P13591,P29317,P02786,O14786,P11279,P08195,P78310,O15118,Q92692 22 +Membrane lipid metabolic process 0.7795130671302725 3.8749971102101606 0.0001066259648421 0.5106343492659953 0.2249415445643765 50 Q92485,P27544,Q9NWW5,P04062,P07602,P06280,P17900,P16278,P50897,Q9NRA0,P06865,Q92484,Q99805,Q13510,P07686,O15269,Q06136,Q96G23,Q9H2C2,Q16739,Q8NCC3,P04066,Q99519,O60512 24 +Vacuole organization 0.72066992947463 3.8185224219626206 0.0001342533838044 0.5933598276445337 0.2249415445643765 62 O14773,Q7Z3C6,Q9NWW5,P04062,Q9Y3E7,O75503,P11117,P50897,P54802,P53365,P10253,P07686,Q14108,Q9NQ11,Q96KQ7,Q9NUM4,Q86Y82,O75787,Q8N511,Q6PHR2,Q8TDY2,Q8NHS3 22 +Receptor mediated endocytosis 0.6423024407871796 3.6023559583853157 0.0003153461444944 0.8792198302441591 0.3318217100196115 72 P07711,O75955,P05067,Q5VW38,P98155,P06756,P50897,Q92673,P11717,Q14108,P98164,P01130,P02786,P46934,P05556,P20645,O00560,P41440,Q07954 19 +Biological process involved in interaction with host 0.6621952274051087 3.5539253789779512 0.0003795268824413 0.9214540887538372 0.3318217100196115 67 P07711,P07858,Q9BTY2,P00533,Q14118,Q8WTV0,Q9Y624,P17301,P35613,P06756,Q96J02,Q14108,P01130,P13591,P29317,P02786,O14786,P11279,P08195,P78310,O15118,Q92692 22 +Lytic vacuole organization 0.8311840751323113 3.504437361905192 0.0004575731966374 0.9534560097941612 0.3318217100196115 27 O14773,P50897,P54802,Q9NUM4,O75787,Q8N511,P10253,Q9NWW5,P04062,P07686,Q8NHS3,Q14108,O75503,P11117 14 +Vacuolar transport 0.6607256535412688 3.503577462977548 0.0004590531193688 0.9539155814094864 0.3318217100196115 66 Q99523,P13473,P07602,Q9UEU0,Q92673,P51809,P11717,Q13772,Q14108,Q9NQ11,Q9NUM4,P11279,P46934,P20645,O60291,Q9BRG1,Q9UNK0,Q92783,Q07954,Q9NZ43,O15118 21 +Anion transport 0.6414547106255295 3.499929227582592 0.0004653816970987 0.9558302060890784 0.3318217100196115 87 P14174,Q8TB61,Q96QD8,Q4KMQ2,Q9C0H2,P07602,P55011,O43865,Q96NB2,Q8IWT6,Q9UHG3,P33527,P51790,P11166,P51798,Q86WC4,P98164,Q9H813,Q9H2D1,Q08722,Q9H0H5,Q15043,Q7L0J3,P05556,P21796,Q99808,P45880,Q9H2J7,Q9BXP2,Q9Y619,P08195,P30825,P41440,Q9Y277,Q92581,Q9Y6M7 36 +Ceramide metabolic process 0.8342511257539149 3.4408380156088216 0.0005799155944379 0.979508020189186 0.3318217100196115 25 Q96G23,Q9NRA0,P06865,P27544,Q99805,Q13510,O60512,Q9NWW5,P04062,P07686,O15269,P06280,Q16739,Q8NCC3,P17900,Q99519 16 +Cellular monovalent inorganic cation homeostasis 0.7773934100257809 3.3322633063191844 0.0008614271192932 0.9968981997629092 0.3318217100196115 30 Q93050,P50897,Q9NUM4,Q15904,P51790,O75787,Q8N511,Q05086,Q9Y487,Q92544,Q92581,P05026,O75503,Q9Y6M7 14 +Antigen processing and presentation 0.7999100711148893 3.33085421751478 0.0008657993184728 0.9969878477460014 0.3318217100196115 27 Q99538,Q9UIQ6,P07711,P04439,P01889,P10321,P04062 7 +Monovalent inorganic cation homeostasis 0.7334543695003257 3.322223726325954 0.0008930305850614 0.9974907340224798 0.3318217100196115 35 Q93050,P50897,Q9NUM4,Q15904,P51790,O75787,Q8N511,Q9BXP2,Q05086,P04899,Q9Y487,Q92544,Q92581,P05026,O75503,Q9Y6M7 16 +Regulation of cellular ph 0.7992824304285147 3.287748210104698 0.0010099211946736 0.998854497611878 0.3318217100196115 26 Q93050,P50897,Q9NUM4,Q15904,P51790,O75787,Q8N511,Q05086,Q9Y487,Q92544,Q92581,O75503,Q9Y6M7 13 +Regulation of ph 0.7992824304285147 3.287748210104698 0.0010099211946736 0.998854497611878 0.3318217100196115 26 Q93050,P50897,Q9NUM4,Q15904,P51790,O75787,Q8N511,Q05086,Q9Y487,Q92544,Q92581,O75503,Q9Y6M7 13 +Liposaccharide metabolic process 0.8141921703165427 3.26173492440852 0.0011073263659049 0.999404085430764 0.3318217100196115 23 P16278,P06865,O60512,P04062,P07686,P06280,Q16739,P17900,P04066,Q99519 10 +Lysosomal transport 0.6730554498547819 3.2540223880476176 0.0011378331225364 0.9995143873657604 0.3318217100196115 55 Q99523,Q9NUM4,P11279,P20645,O60291,O15118,P13473,Q92673,Q9UNK0,P07602,P51809,P46934,P11717,Q13772,Q07954,Q9NZ43,Q14108,Q9NQ11 18 +Carbohydrate derivative catabolic process 0.6979815691078223 3.222288280180403 0.0012717111273319 0.9998022351731574 0.3318217100196115 45 P07711,P16278,Q9H773,P54802,P06865,O00462,Q9BTY2,P13051,P04062,P07686,P04066,P06280,P15586,P08236,Q9Y6X5,P17900,Q01459,Q99519 18 +Membrane lipid catabolic process 0.9125259892643972 3.204343417002162 0.0013537090220323 0.9998859306789418 0.3318217100196115 15 Q92485,P50897,P06865,Q13510,P04062,P07686,P06280,P17900,P04066,Q99519 10 +Glycoprotein metabolic process 0.5939749107457781 3.198447131423542 0.0013816986514332 0.9999054656809958 0.3318217100196115 79 Q9BXS4,P33908,Q86SF2,P07711,O43505,Q9Y287,Q9NX62,Q7LGA3,P35610,Q2TAA5,Q16706,Q99805,O00462,Q10469,Q9Y2G5,P51688,Q8WVQ1,Q9NQX7,Q86YN1,Q8NCH0,Q04656,O94766,Q8N6G5,Q9H0U4,O00754,Q9P2E5,Q92542,Q10472,O60512,Q9Y673,O15118,Q9H9S5 32 +Antigen processing and presentation of peptide antigen 0.8866903837341105 3.0859794959815754 0.002028828120469 0.9999987730976072 0.3318217100196115 15 Q99538,Q9UIQ6,P07711,P04439,P01889,P10321 6 +Steroid metabolic process 0.5845431762064612 3.053088338657746 0.0022649925083986 0.9999997488453782 0.3318217100196115 83 Q9BQE5,Q9NWW5,P04062,Q8WTV0,P05067,P98155,Q99538,Q9BXW6,O95470,P61916,O75845,P56937,Q13510,Q16850,P38571,P98164,P01130,Q15392,Q15800,Q9H2C2,P34913,O15118 22 +Locomotory behavior 0.7066765036024114 3.0452970085018984 0.0023245063269718 0.9999998316088128 0.3318217100196115 33 P50897,P54802,P51790,Q04656,P10253,O75844,P07686,P05067,O15118,Q05086 10 +Aminoglycan metabolic process 0.7732656918108874 3.0390029988116587 0.0023736249164387 0.9999998789356932 0.3318217100196115 23 P16278,O43505,P51688,P54802,P06865,Q8NCH0,Q9NX62,P04066,P07686,Q7LGA3,P15586,P08236,Q01459,Q8N6G5 14 +Taxis 0.574997654746943 3.026144581717357 0.0024769383197373 0.999999939524878 0.3318217100196115 79 P14174,Q13740,Q4KMQ2,Q14118,P55011,P05067,P51805,Q99538,P17301,P35613,P06756,P11233,O15031,P33176,Q07021,P33527,Q13641,P13591,Q9BVA1,P29317,O14786,P42892,Q04721,Q92859,Q00013,O94813,Q15375,P78310,Q9Y6N7 29 +Positive regulation of cell adhesion 0.5702203405033286 3.0150839857561844 0.0025690810592147 0.9999999674385384 0.3318217100196115 73 P23458,O75955,Q14118,P07947,Q9Y624,P17301,P06756,Q07021,P04439,P14543,Q08722,P02786,O95819,O14786,Q14254,O00592,P30825,P41440,Q9HCL2 19 +Negative regulation of response to external stimulus 0.6346172100240406 3.0137735650310455 0.0025802030281298 0.9999999697832144 0.3318217100196115 57 Q92485,P14174,P01889,P80303,P04062,P07947,P51805,Q07021,Q96J02,O94898,P01130,Q96G23,P04439,O43657,O14936,O14786,O94813,Q6YHK3,Q9Y6N7 19 +Cell cell adhesion via plasma membrane adhesion molecules 0.7491339820590136 3.003732022240464 0.0026669011167816 0.9999999831252476 0.3318217100196115 26 P35613,Q14517,Q14126,Q9P273,O15031,Q9BY67,Q14574,O00192,P98194,P10586,Q9BQT9,P78310,Q92692,Q9Y6N7,O60245,P05556 16 +Inorganic anion transport 0.6798521641850372 2.9747326974675694 0.0029324395145062 0.9999999971674316 0.3318217100196115 35 Q4KMQ2,Q9C0H2,P55011,P08183,Q8IWT6,Q9UHG3,P33527,P51790,Q9Y666,P51798,Q86WC4,Q9H813,P22413,Q9H0H5,Q15043,P21796,O43681,P45880,Q9BXP2,Q9Y277,Q9Y6M7 21 +Regulation of nervous system development 0.5718146894645123 2.9665607192642525 0.0030115089008919 0.9999999983352396 0.3318217100196115 81 Q9P265,P55209,Q14118,P51805,Q16706,P53634,O15031,Q92673,Q06481,Q9BQT9,Q13641,P98164,P01130,Q96G23,O14786,O94813,Q15375,Q13049,Q9Y6N7 19 +Regulation of neuron projection development 0.5773952775115507 2.9578279549726276 0.0030981498838005 0.9999999990701816 0.3318217100196115 85 Q9P265,Q9P273,Q9UL15,Q13308,P51805,Q9ULH0,P98155,Q9H4M9,Q32P28,O15031,O94898,Q14012,Q14108,Q96G23,Q9NUM4,Q6PIJ6,Q9NQX7,P10586,Q9NV96,O14786,P46934,Q9UQB8,O94813,Q15375,Q8WWV3,Q05086,Q9Y6N7,P08670 28 +Glycosphingolipid metabolic process 0.8991075963802375 2.953253668890224 0.0031444345426419 0.9999999993188255 0.3318217100196115 13 P16278,P06865,O60512,P04062,P07686,P06280,Q16739,P17900,Q99519 9 +Anion transmembrane transport 0.63770766781031 2.9423604400704395 0.0032572056444812 0.9999999996808696 0.3318217100196115 53 Q8TB61,Q4KMQ2,P55011,Q96NB2,Q8IWT6,Q9UHG3,P33527,P51790,P51798,P98164,Q9H2D1,P05556,P21796,P45880,Q9BXP2,Q9Y619,P08195,P30825,P41440,Q9Y277,Q92581,Q9Y6M7 22 +Protein maturation 0.5686469755136087 2.937334386636137 0.003310469375688 0.999999999776938 0.3318217100196115 81 Q9BXS4,Q99538,P42892,P07711,Q92896,Q86UY6,Q15392,Q92542,O75844,Q92673,P16870,O75976,Q2T9J0,O75503,Q9H9S5 15 +Ph reduction 0.8325786982170398 2.932467698025257 0.0033627990253148 0.9999999998431072 0.3318217100196115 16 Q93050,P50897,Q9NUM4,P51790,Q8N511,O75787,Q05086,Q9Y487,O75503 9 +Behavior 0.5822658687681039 2.928704137765622 0.0034037824160542 0.9999999998809004 0.3318217100196115 90 P04062,P00533,P05067,P17900,P98155,Q99538,P50897,P54802,P51790,P10253,P07686,O60266,Q96KQ7,Q13641,P01130,Q04656,O75844,P05556,Q92542,O15118,Q05086 21 +Lysosomal protein catabolic process 0.9117568066209876 2.9233497361759815 0.0034628732070134 0.9999999999199568 0.3318217100196115 12 P01130,O14773,Q9NUM4,Q8N511,P04062,P13473,Q07954,Q8NHS3,P98164 9 +Protein catabolic process in the vacuole 0.9117568066209876 2.9233497361759815 0.0034628732070134 0.9999999999199568 0.3318217100196115 12 P01130,O14773,Q9NUM4,Q8N511,P04062,P13473,Q07954,Q8NHS3,P98164 9 +Protein processing 0.6250857872861757 2.914735197118405 0.0035599045533165 0.999999999958322 0.3318217100196115 56 Q9BXS4,Q99538,P42892,P07711,Q92896,Q15392,Q92542,P22694,O75844,O75503,O75976,Q2T9J0,P16870,Q9H9S5 14 +Membrane fusion 0.63956706443911 2.895030693480858 0.0037912146024934 0.9999999999912064 0.3318217100196115 50 P07711,Q9P2R3,P51149,O15400,Q9Y3E7,Q8WUH2,Q9H270,Q9UEU0,Q99747,Q13190,O95249,O95721,P51809,P54920,Q9NQ11,Q9P2W9,P08754,Q86Y82,O00429,Q5SQN1,O43752,P31751,O00161,Q9UNK0,Q9NZ43,Q92692 26 +Biological process involved in symbiotic interaction 0.5810354229845441 2.8736255540087603 0.0040578975110432 0.9999999999985382 0.3318217100196115 93 P07711,P07858,Q9BTY2,Q14118,P00533,Q8WTV0,Q9Y624,P17301,P35613,P06756,Q96J02,P11717,Q14108,P01130,P13591,P29317,P02786,O14786,P11279,P05556,P27105,Q06787,P08195,P78310,O15118,Q92692 26 +Sphingolipid biosynthetic process 0.777637374029765 2.867786801744504 0.0041335397128627 0.9999999999991214 0.3318217100196115 20 Q96G23,Q9NRA0,P27544,Q99805,Q13510,O60512,P04062,O15269,Q16739,Q06136 10 +Homophilic cell adhesion via plasma membrane adhesion molecules 0.8088647945663162 2.864865245610919 0.0041718673201105 0.9999999999993212 0.3318217100196115 17 P35613,Q14517,Q14126,Q9P273,Q9BY67,Q14574,Q9BQT9,Q92692,Q9Y6N7,O60245,P05556 11 +Neuromuscular process controlling balance 0.8791613852006054 2.8644604483603877 0.0041772031712397 0.9999999999993452 0.3318217100196115 13 O14773,P17900,P05067,P10253 4 +Adult behavior 0.7621472251153001 2.8452536676687967 0.0044376067864169 0.9999999999998864 0.3318217100196115 21 P50897,Q92542,P51790,O15118,P05067,Q96KQ7 6 +Neurotransmitter transport 0.6958011645435274 2.839592299596586 0.0045171225068547 0.9999999999999336 0.3318217100196115 30 Q4J6C6,P05556,Q99808,P50897,Q9H2J7,Q96QD8,O00161,O75955,Q06787,O14936,Q7L0J3,O95721,Q5SQN1,Q15833,P0DP25,P41440,P56545 17 +Organic anion transport 0.6120280181459357 2.8368220199555263 0.0045565003975955 0.999999999999949 0.3318217100196115 57 P14174,Q8TB61,Q96QD8,P07602,P55011,Q96NB2,Q8IWT6,P11166,P98164,Q9H2D1,Q08722,P05556,Q7L0J3,Q99808,Q9H2J7,Q9Y619,P08195,P30825,P41440,Q9Y6M7 20 +Sterol metabolic process 0.6341320502464469 2.8362463791053387 0.0045647217075179 0.9999999999999518 0.3318217100196115 49 Q9BQE5,P01130,Q9BXW6,Q15392,P61916,P56937,O75845,Q9NWW5,P04062,Q15800,Q9H2C2,Q16850,P34913,P38571,Q8WTV0,O15118,P05067,P98155 18 +Phagocytosis 0.6357793995813997 2.8309143785456756 0.004641514430181 0.9999999999999712 0.3318217100196115 48 P17301,P01130,P06756,Q07954,Q08431,P51790,Q08722,Q4KMQ2,Q5KU26,Q06481,P51809,Q92544,Q8WTV0,P05556 14 +Carbohydrate derivative transport 0.7699478061187791 2.826978798333873 0.0046989438875153 0.9999999999999803 0.3318217100196115 20 P61916,Q08722,P07602,P41440,Q8WTV0,P98155 6 +Cognition 0.645386040197052 2.82466815882689 0.0047329605556352 0.9999999999999843 0.3318217100196115 43 Q99538,P01130,P50897,Q92542,P00533,O60266,P05067,P17900,Q96KQ7,Q13641,P05556,P98155 12 +Immune response regulating signaling pathway 0.5706882660196231 2.8222239659668897 0.0047691858197072 0.9999999999999878 0.3318217100196115 68 Q92485,Q9NUD5,Q5KU26,O75955,P07947,Q07021,Q96J02,Q07666,Q06481,Q7KYR7,Q6AZY7,Q5ZPR3,Q9UBC1,P04439,Q08722,O43164,O43657,Q14254,Q9NPR9,P41440,Q92692 21 +Multi multicellular organism process 0.6553603787035107 2.8188278717640225 0.0048199357399696 0.9999999999999912 0.3318217100196115 36 P17301,Q9BQE5,P35613,Q9UIQ6,Q9NRA0,P07858,Q07021,Q96QD8,P07686,P11166,P41440,P19021 12 +Regulation of neurogenesis 0.5577151403535283 2.818753351861874 0.0048210547950209 0.9999999999999916 0.3318217100196115 71 P01130,Q96G23,Q9P265,Q16706,O15031,P55209,O94813,Q15375,Q14118,Q92673,Q06481,O14786,Q9Y6N7,P51805,P98164,Q13049 16 +Positive regulation of response to external stimulus 0.5658790927505711 2.8160068065322017 0.0048624636493141 0.9999999999999934 0.3318217100196115 69 Q99538,P17301,P01130,P14174,O43405,P53634,Q07021,Q08722,O94813,P51809,O14786,P11279,P05067,Q13641,Q92692 15 +Endosome organization 0.6630012737336054 2.8112529385374456 0.0049348974108827 0.999999999999996 0.3318217100196115 34 Q9UK41,Q9H9H4,O43752,Q8TCG2,Q13501,Q12768,Q9BTU6,P51790,P51149,Q9BRG1,Q96ED9,Q9H270,Q9Y3E7,Q92783,Q14108,O14964 16 +Transition metal ion homeostasis 0.6976676567840794 2.810443947082413 0.0049473205737828 0.9999999999999964 0.3318217100196115 29 P02792,P30519,Q92859,Q15904,Q8N511,P02786,Q15043,Q9Y487,Q13772,P05067,Q9NQ11 11 +Chloride transport 0.7945445755469255 2.7930050109741966 0.0052220882988058 0.9999999999999994 0.3318217100196115 17 Q8IWT6,Q9UHG3,P51790,Q4KMQ2,Q9BXP2,Q9C0H2,P55011,P51798,Q86WC4,Q9H813 10 +Lipid localization 0.5773056891915904 2.7813071019711075 0.0054140494824141 1.0 0.3318217100196115 97 Q9BQE5,P14174,Q7Z3C6,P23786,Q4KMQ2,P04062,P07602,Q8WTV0,P17900,P98155,P06756,Q9BXW6,P61916,P07686,P11166,O15260,Q14108,P01130,Q86Y82,Q9H2C2,Q9NV96,Q16739,P35790,P31751,O14678,Q07954,O15118 27 +Neuromuscular process 0.6864254988863633 2.7809910502395176 0.0054193231153747 1.0 0.3318217100196115 30 O14773,P10253,P04062,P07686,P05067,P17900 6 +Amyloid precursor protein metabolic process 0.7372373487992567 2.7712146702049822 0.005584759438401 1.0 0.3318217100196115 22 Q15392,Q9NQX7,P15260,Q9Y287,Q92673 5 +Myeloid leukocyte activation 0.6837833437291759 2.7643987229346108 0.0057027807149727 1.0 0.3318217100196115 30 Q04721,P01130,P14174,Q9NRA0,P53634,P15260,O00161,O43164,P51809,P05067,Q92692 11 +Receptor metabolic process 0.6376702863205543 2.757095285957986 0.0058317354804788 1.0 0.3318217100196115 42 Q99538,P01130,P42892,O75955,Q92673,Q96J02,P02786,Q9H3E2,O00560,P41440,Q07954,P46934,P05556 13 +Positive regulation of synaptic transmission 0.7659138337386329 2.749169692263538 0.0059746446323984 1.0 0.3318217100196115 19 Q99538,Q13501,Q92542,Q14168,O75955,Q9BQT9,P41440,P05067 8 +Organophosphate ester transport 0.6454750753673485 2.7437944920014306 0.0060733545766429 1.0 0.3318217100196115 35 Q8IWT6,P01130,Q99808,Q9H2D1,Q7Z3C6,Q8TB61,P61916,Q08722,Q4KMQ2,Q9NV96,P41440,Q8WTV0,Q14108 13 +Neuron projection guidance 0.6515203378123271 2.734564673828981 0.0062462823416997 1.0 0.3318217100196115 34 P42892,P35613,Q04721,P13591,Q92859,O15031,P33176,P29317,O94813,Q13740,Q15375,Q14118,O14786,P05067,P51805,Q9Y6N7 16 +Leukocyte mediated cytotoxicity 0.7822602720501817 2.730822811757093 0.0063176427722164 1.0 0.3318217100196115 17 P04439,P01889,Q9BY67,P33176,P53634,P07437,O15400,P51809,Q15833,P11279,Q92692 11 +Cellular transition metal ion homeostasis 0.7058001913738364 2.71712692035895 0.0065851349855956 1.0 0.3318217100196115 25 P02792,Q15904,Q8N511,P02786,Q15043,Q9Y487,Q13772,P05067,Q9NQ11 9 +Vacuolar acidification 0.8610726305720303 2.701195449329614 0.0069090723795797 1.0 0.3318217100196115 12 Q93050,P50897,Q9NUM4,O75787,Q8N511,Q9Y487,O75503 7 +Iron ion homeostasis 0.7349430250403822 2.6964227193592256 0.0070088658860085 1.0 0.3318217100196115 21 P02792,P30519,Q92859,Q15904,Q8N511,P02786,Q9Y487,Q13772,Q15043 9 +Vitamin transport 0.8593256848315135 2.693422020998824 0.0070722686865876 1.0 0.3318217100196115 12 Q9NPF0,Q9H2D1,P04062,P11166,Q8WTV0,P41440,P98164 7 +Carbohydrate catabolic process 0.5901309428485325 2.6859891390506876 0.0072315439446002 1.0 0.3318217100196115 58 P16278,O00462,P10253,P07686,P08236,P05067,P17900,Q14108,Q01459 9 +Regulation of cellular response to growth factor stimulus 0.6256674295110862 2.6833581322133915 0.0072886891820522 1.0 0.3318217100196115 43 Q04721,Q92896,Q92859,Q9NYA4,O94813,Q9H3E2,Q92673,O14936,O00560,Q6YHK3,Q9Y6N7,P98164 12 +Positive regulation of cell cell adhesion 0.6364996660461814 2.6823988404780743 0.0073096255059343 1.0 0.3318217100196115 35 P04439,Q9HCL2,Q08722,P23458,O75955,P02786,O00592,P30825,P41440,P07947,Q14254,Q9Y624 12 +Ceramide catabolic process 0.9382561785812508 2.6756084126278776 0.0074593743517845 1.0 0.3318217100196115 8 P06865,Q13510,P07686,P06280,P17900,Q99519 6 +Glycolipid catabolic process 0.9376114377500144 2.673025079648906 0.0075170630351357 1.0 0.3318217100196115 8 P06865,P07686,P06280,P17900,P04066,Q99519 6 +Transmembrane receptor protein serine threonine kinase signaling pathway 0.59677055466546 2.6692245435014588 0.0076026605188839 1.0 0.3318217100196115 55 Q04721,Q9UIQ6,Q92896,Q92859,Q9NYA4,Q9H3E2,Q92673,Q06481,O00560,Q6YHK3,Q07954,P98164 12 +Selective autophagy 0.6326190657720994 2.6628599334826006 0.0077479657521755 1.0 0.3318217100196115 36 P21796,P53365,Q13501,Q9Y6I9,O15269,Q13137,Q8TDY2 7 +Negative regulation of nervous system development 0.6953674644719502 2.6553310409861797 0.0079230612998346 1.0 0.3318217100196115 25 P01130,Q96G23,Q9P265,Q15375,Q92673,Q06481,O14786,P51805 8 +Sterol transport 0.6665394304626042 2.655254972922238 0.0079248483149418 1.0 0.3318217100196115 30 P01130,Q07954,Q86Y82,P61916,Q9H2C2,Q8WTV0,O15118 7 +Organelle membrane fusion 0.6313252430009183 2.6538956545074637 0.0079568427746055 1.0 0.3318217100196115 36 Q9P2R3,P51149,Q8WUH2,O15400,Q9Y3E7,Q9H270,Q9UEU0,Q13190,O95249,O95721,P51809,Q9NQ11,P08754,Q86Y82,Q5SQN1,O43752,P31751,O00161,Q9UNK0 19 +Regulation of neurotransmitter levels 0.6528029302426698 2.650268548985917 0.0080427813197705 1.0 0.3318217100196115 32 Q4J6C6,P05556,Q99808,P50897,P21964,O00161,O75955,Q06787,O14936,Q7L0J3,O95721,Q8NCG7,Q5SQN1,Q15833,P0DP25,P41440,P56545 17 +Secondary alcohol metabolic process 0.5989015512752185 2.6439396831124777 0.0081947257562393 1.0 0.3318217100196115 53 Q9BQE5,P01130,Q9BXW6,Q15392,P61916,P56937,O75845,Q9NWW5,P04062,Q15800,Q9H2C2,Q16850,P34913,P48735,Q8WTV0,O15118,P05067,P98155 18 +Aminoglycan catabolic process 0.9486282947821464 2.6353415809722542 0.0084052650854808 1.0 0.3318217100196115 7 P16278,P54802,P04066,P08236,P15586,Q01459 6 +Establishment of protein localization to vacuole 0.6969805175488174 2.634617239852144 0.0084232208817085 1.0 0.3318217100196115 24 Q99523,P20645,Q9BRG1,P13473,Q92673,Q13772,Q14108,P46934 8 +Inflammatory response 0.5505431749194001 2.632589786084998 0.0084736622639851 1.0 0.3318217100196115 90 Q92485,Q9BQE5,P14174,P42785,Q4KMQ2,P04062,Q8NCG7,P05067,Q9Y624,P48960,P17301,Q8IV08,P53634,Q96J02,Q06481,P51809,P38571,P01130,P29317,Q08722,P02786,P05556,Q04721,O75882 24 +Immune effector process 0.5463834360714926 2.622989370408232 0.0087161991892166 1.0 0.3318217100196115 88 P14174,P01889,O15400,P05067,P07947,Q9NQZ7,Q9NRA0,P53634,Q07021,Q9Y2Y6,Q06481,P51809,P04439,Q9BY67,Q6PIJ6,Q08722,P13051,Q04656,P02786,P11279,Q9UQ84,Q04721,O00161,Q07954,Q92692 25 +Leukocyte proliferation 0.6216003499372628 2.620392645514009 0.0087828578312267 1.0 0.3318217100196115 40 Q9NPF0,P14174,P04439,Q92542,P04062,P10644,Q96J02,P02786,P30825,Q9HCL2 10 +Substrate dependent cell migration 0.8426443903940414 2.6187948711407563 0.0088240991429102 1.0 0.3318217100196115 12 O00560,O94813,Q9Y6N7,O14786 4 +Glycoprotein biosynthetic process 0.5471621131378898 2.612492386396969 0.0089884694343862 1.0 0.3318217100196115 68 P33908,Q86SF2,Q9BXS4,O43505,Q9Y287,Q7LGA3,P35610,Q2TAA5,Q16706,Q99805,Q10469,Q9Y2G5,Q8WVQ1,Q9NQX7,Q86YN1,Q8NCH0,Q04656,O94766,Q8N6G5,Q9P2E5,Q10472,Q92542,O60512,Q9Y673,O15118,Q9H9S5 26 +Protein localization to vacuole 0.6717851113917886 2.612381873670404 0.0089913758641946 1.0 0.3318217100196115 28 Q99523,P20645,Q9BRG1,P13473,Q92673,P46934,Q13772,Q14108,Q9NQ11 9 +Negative regulation of cell development 0.6646293791277833 2.604285996292936 0.0092065896277586 1.0 0.3318217100196115 29 P01130,Q96G23,Q9P265,Q15375,Q92673,Q06481,O14786,P51805 8 +Positive regulation of cell projection organization 0.5332183810059291 2.603885202552112 0.0092173624307279 1.0 0.3318217100196115 81 Q9P273,Q9Y6W5,Q16625,Q13308,P51805,Q9ULH0,P98155,P17301,Q9H4M9,P11233,Q32P28,O15031,Q14108,O14641,Q9NUM4,Q6PIJ6,Q04656,Q9NV96,O14786,Q9UQB8,O94813,Q06787,Q9Y6N7 23 +Organic acid transmembrane transport 0.6212737795124827 2.59953110506743 0.0093351217856134 1.0 0.3318217100196115 38 P05556,Q9H2D1,P31751,Q96QD8,P23786,Q9H2J7,O14678,Q9Y619,P08195,P30825,P11166,P41440,P98164 13 +Gliogenesis 0.5669898106695695 2.5991114558617565 0.0093465420832627 1.0 0.3318217100196115 62 P01130,Q96G23,Q07954,Q7Z4L5,P15260,Q92542,P31751,Q9Y2Y6,P04062,Q14118,P07686,P07942,P05067,P98164,P08670 15 +Antigen processing and presentation of exogenous antigen 0.8784999264427735 2.5963165528485654 0.0094229208075067 1.0 0.3318217100196115 10 Q99538,Q9UIQ6,P07711,P04439 4 +Vitamin transmembrane transport 0.9182711144045224 2.595132466178626 0.0094554469168635 1.0 0.3318217100196115 8 P04062,Q8WTV0,Q9H2D1,P98164 4 +Negative regulation of proteolysis 0.5224866509052795 2.594454510515085 0.0094741149765689 1.0 0.3318217100196115 75 Q9BXS4,Q07954,Q92896,P07858,Q9UL15,Q15392,Q96K76,Q96KC8,Q92673,O94898,Q06481,O00560,Q6YHK3,P05067,Q9H2J4 15 +Antigen processing and presentation of exogenous peptide antigen 0.9376876583484484 2.592146952495279 0.0095379020580772 1.0 0.3318217100196115 7 Q99538,Q9UIQ6,P07711,P04439 4 +T cell activation 0.5712434920556707 2.580970210332913 0.0098523083028279 1.0 0.3318217100196115 60 Q9NQZ7,P07711,P04439,Q9BY67,Q92542,Q9HCL2,Q08722,Q04656,Q9Y2Y6,P04062,Q96J02,P24390,P10644,P02786,P30825,P78310,P07947,Q14254 18 +Positive regulation of erk1 and erk2 cascade 0.7141430504695994 2.580681679313126 0.009860545663529 1.0 0.3318217100196115 21 Q04721,P14174,P00533,O14786,P05067,Q13641 6 +Cellular iron ion homeostasis 0.7529256318850983 2.580274648945571 0.0098721765327636 1.0 0.3318217100196115 17 P02792,Q15904,Q8N511,P02786,Q9Y487,Q13772,Q15043 7 +Oligosaccharide metabolic process 0.8747049643432455 2.5801471440303394 0.0098758224917625 1.0 0.3318217100196115 10 O00462,P10253,P07686,P06280,P17900,Q01459 6 +Positive regulation of neuron projection development 0.6204319031877525 2.578025610575619 0.0099366633072042 1.0 0.3318217100196115 36 Q9H4M9,Q9P273,Q9NUM4,Q32P28,O15031,Q6PIJ6,Q9UQB8,Q13308,Q9NV96,Q14108,Q9ULH0,P98155 12 +Antigen processing and presentation of peptide antigen via mhc class i 0.8536251891988833 2.5760748391828754 0.0099929014807227 1.0 0.3318217100196115 11 P10321,Q9UIQ6,P04439 3 +Smooth muscle cell migration 0.7793405569161143 2.5736379993788754 0.0100635505239716 1.0 0.3318217100196115 15 P17301,O94813,Q04656,Q13685,Q14344,Q92673,O14786,P31949,Q07954 9 +Carboxylic acid transport 0.6128933117854056 2.568071241818671 0.0102266136150432 1.0 0.3318217100196115 41 Q8IWT6,P05556,P14174,Q9H2D1,Q9H2J7,Q96QD8,Q9Y619,P07602,P08195,P55011,P30825,Q7L0J3,P41440,P98164,Q96NB2 15 +Protein localization to lysosome 0.7317854330163178 2.5672639696496424 0.0102504547203372 1.0 0.3318217100196115 19 Q99523,P20645,P13473,Q92673,Q13772,Q14108,Q9NQ11 7 +Regulation of chemotaxis 0.6576983812636791 2.560351958383468 0.0104566203851539 1.0 0.3318217100196115 29 Q99538,P17301,P14174,Q07021,Q00013,O94813,O14786,P51805,Q13641,Q9Y6N7 10 +Regulation of pattern recognition receptor signaling pathway 0.6775891089812147 2.5488969533161314 0.0108064225818147 1.0 0.3318217100196115 25 Q92485,Q9NUD5,Q07021,O75955,O43164,O43657,Q06481,Q9NPR9,P41440,Q14254,Q9UBC1 11 +T cell proliferation 0.676720498280077 2.5436598980508256 0.010969783610321 1.0 0.3318217100196115 25 P04439,Q9BY67,Q92542,Q96J02,P10644,P02786,P30825,Q9HCL2 8 +Regulation of multicellular organism growth 0.7543141071449168 2.5422957633226426 0.0110126941104997 1.0 0.3318217100196115 16 Q99538,P05067,Q9HCL2,O75882 4 +Endocytosis 0.6196175691422293 2.537550167534183 0.0111631367219009 1.0 0.3318217100196115 145 Q99523,P07711,Q9Y6W5,Q4KMQ2,Q5KU26,O75955,Q08380,P05067,Q8WTV0,Q5VW38,Q9H223,P98155,P17301,P06756,P50897,P51790,Q92673,Q06481,P51809,P11717,O15260,Q6AZY7,Q14108,P98164,Q9UBG0,P01130,Q9NPF0,P02786,P46934,P05556,Q9UKS6,Q08431,P20645,Q06787,O00560,P41440,Q07954,O15118,Q05086 39 +Lymphocyte mediated immunity 0.6097178743109228 2.535130826202903 0.0112405337992318 1.0 0.3318217100196115 40 P04439,P53634,P01889,Q07021,P13051,P02786,O15400,P51809,P11279,Q9UQ84,Q92692 11 +Membrane lipid biosynthetic process 0.6525199886242438 2.5273687805648852 0.0114920759642249 1.0 0.3318217100196115 29 Q96G23,Q9NRA0,P27544,Q99805,Q13510,O60512,P04062,O15269,Q16739,Q06136 10 +Transition metal ion transport 0.7506617041844486 2.523596029558276 0.0116161329313098 1.0 0.3318217100196115 16 P02792,O15173,Q04656,P02786,Q8N4V1,Q9HD20,Q15043 7 +Positive regulation of leukocyte proliferation 0.7411702243529785 2.519112947579482 0.0117650910130335 1.0 0.3318217100196115 17 Q9NPF0,P04439,P02786,P30825,Q9HCL2 5 +Cell recognition 0.6655354155939426 2.506398645301908 0.0121968020183806 1.0 0.3318217100196115 26 P35613,P45880,Q08431,Q5KU26,O14786,Q8WTV0,Q9Y6N7,P05067 8 +Regulation of leukocyte proliferation 0.6654515128755855 2.5058834699477575 0.012214586825169 1.0 0.3318217100196115 26 Q9NPF0,P14174,P04439,P02786,P10644,P30825,Q9HCL2 7 +Ceramide biosynthetic process 0.7998336247083836 2.5007628762937517 0.0123926122909161 1.0 0.3318217100196115 13 Q96G23,Q9NRA0,Q13510,O60512,P04062,O15269,Q16739 7 +Protein targeting to vacuole 0.7098985284572538 2.500718192191622 0.012394175865843 1.0 0.3318217100196115 20 Q99523,P20645,P13473,Q92673,Q13772,Q14108 6 +Regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.6166209184551089 2.496872613875002 0.0125293957092473 1.0 0.3318217100196115 34 Q04721,Q92896,Q92859,Q9NYA4,Q92673,O00560,Q6YHK3,Q07954,P98164 9 +Myeloid leukocyte migration 0.6636209063763389 2.4946349407257262 0.0126086774710334 1.0 0.3318217100196115 26 Q99538,P35613,P14174,Q07021,Q00013,Q08722,O94813,P78310 8 +Vascular transport 0.7363449454606854 2.493867529503001 0.0126359692894506 1.0 0.3318217100196115 17 Q99808,Q96QD8,P02786,P30825,P11166,P55011,Q07954,P41440,P98164 9 +T cell mediated cytotoxicity 0.8931282256983354 2.492699328803647 0.0126776149758411 1.0 0.3318217100196115 8 P04439,P01889,P53634,O15400,Q92692 5 +Toll like receptor signaling pathway 0.6982817677696682 2.4912561642296236 0.0127292306896389 1.0 0.3318217100196115 21 Q92485,Q5KU26,O75955,Q9NPR9,Q06481,P41440,Q6AZY7,Q14254,Q9UBC1 9 +Muscle cell migration 0.7346865092762053 2.485171778628843 0.0129488934146255 1.0 0.3318217100196115 17 P17301,O94813,Q04656,Q13685,Q14344,Q92673,O14786,P31949,Q07954 9 +Regulation of lysosomal protein catabolic process 0.9105596970339728 2.4840175918104617 0.0129909390204121 1.0 0.3318217100196115 7 P01130,P04062,Q07954,Q8NHS3,P98164 5 +Regulation of protein catabolic process in the vacuole 0.9105596970339728 2.4840175918104617 0.0129909390204121 1.0 0.3318217100196115 7 P01130,P04062,Q07954,Q8NHS3,P98164 5 +Protein targeting to lysosome 0.7611051358723759 2.4831128436322607 0.0130239822726492 1.0 0.3318217100196115 15 Q99523,P20645,P13473,Q92673,Q13772,Q14108 6 +Adaptive immune response 0.5809047637185897 2.4830936776217913 0.0130246830578677 1.0 0.3318217100196115 52 Q9NQZ7,P07711,P04439,P53634,P01889,Q9BY67,Q07021,P10321,P13051,Q9Y2Y6,P02786,O15400,Q9UQ84,Q92692 14 +Pattern recognition receptor signaling pathway 0.602449631061327 2.4825389036451924 0.0130449822508054 1.0 0.3318217100196115 40 Q92485,Q07021,Q5KU26,O75955,Q96J02,O43164,Q06481,O43657,Q9NPR9,P41440,Q6AZY7,Q14254,Q9UBC1 13 +Glycoside catabolic process 0.950184116702664 2.4797361092946506 0.0131479649343186 1.0 0.3318217100196115 6 P04066,P06280,P08236,Q9BTY2 4 +Adult locomotory behavior 0.7418757216299483 2.478427456093485 0.0131962943100287 1.0 0.3318217100196115 16 O15118,P05067,P51790,P50897 4 +Regulation of toll like receptor signaling pathway 0.7943981943381113 2.4752020562882873 0.0133160815773147 1.0 0.3318217100196115 13 Q92485,O43164,O75955,Q9NPR9,Q06481,P41440,Q14254,Q9UBC1 8 +Mucopolysaccharide metabolic process 0.8107791460643062 2.4741938409051136 0.0133537220922659 1.0 0.3318217100196115 12 P16278,O43505,Q8NCH0,Q9NX62,P15586,Q8N6G5 6 +Glycosaminoglycan catabolic process 0.9483732186071462 2.472709620498952 0.0134093048099233 1.0 0.3318217100196115 6 P16278,P54802,P08236,P15586,P04066 5 +Oligosaccharide catabolic process 0.975537634408603 2.472702082243988 0.0134095876318685 1.0 0.3318217100196115 5 P07686,P17900,Q01459,O00462 4 +Protein localization to plasma membrane 0.5234187314031382 2.463088592711363 0.0137745875400847 1.0 0.3318217100196115 84 Q9BXS4,Q13501,Q15904,O75955,P00533,O15400,Q9H223,Q9UEU0,Q9Y624,P35613,Q9H4M9,Q13641,Q4J6C6,P29317,Q14254,P05556,P31751,Q9UNK0,P41440,Q07954,P05026 21 +Organelle fusion 0.5757561008306418 2.46084095453957 0.01386117973486 1.0 0.3318217100196115 53 Q9P2R3,P51149,Q8WUH2,O15400,Q9Y3E7,Q9H270,Q9UEU0,Q9NWX6,Q8IWA4,P04083,Q13190,O95249,Q99536,O95721,P51809,Q9NQ11,P08754,Q8N2A8,Q86Y82,Q9GZY8,P02786,O95140,Q5SQN1,O14653,O43752,P31751,O00161,Q9UNK0,Q9Y3D6 29 +Positive regulation of cell killing 0.884656447019532 2.457883308349128 0.0139758577652118 1.0 0.3318217100196115 8 P04439,P01889,O15400,P11279,Q92692 5 +Regulation of plasma lipoprotein particle levels 0.7207410710984697 2.457872058778425 0.0139762955434781 1.0 0.3318217100196115 18 P01130,Q9H4M9,P17252,P61978,P22694,P38571,P17612,Q8WTV0,P35610,P98155 10 +Regulation of glycoprotein metabolic process 0.7889887197774264 2.4496793514260675 0.0142983481074159 1.0 0.3318217100196115 13 Q9BXS4,Q9NQX7,Q92542,Q9Y287 4 +Regulation of cell cell adhesion 0.5715859507656796 2.446761150290522 0.0144146328518763 1.0 0.3318217100196115 54 P04439,Q9P273,P41440,Q9HCL2,Q08722,P23458,O75955,Q96J02,P10644,P02786,O00592,Q15375,P30825,P07947,Q14254,Q9Y624 16 +Proteoglycan metabolic process 0.7707117938491311 2.443486516497736 0.0145461131365991 1.0 0.3318217100196115 14 P51688,Q8WVQ1,Q9P2E5,Q99805,Q8NCH0,Q9NX62,Q7LGA3,Q8N6G5 8 +Amyloid beta clearance 0.7870458677577195 2.4404921727121565 0.014667263797834 1.0 0.3318217100196115 13 P01130,P15260,P98164,Q07954 4 +Adenylate cyclase modulating g protein coupled receptor signaling pathway 0.6892616473323144 2.4399425385320894 0.0146895982687991 1.0 0.3318217100196115 21 P08754,P09471,Q9Y6W5,P22694,Q14344,P07602,P04899,O60266,P63096,P29992,P48960 11 +Cerebellar cortex development 0.725445671070159 2.4365402818094033 0.0148285177755989 1.0 0.3318217100196115 17 P54802,Q7Z4L5,Q04656,Q5KU26,P04062 5 +Positive regulation of inflammatory response 0.7243206241633058 2.4305987641979176 0.0150738971416248 1.0 0.3318217100196115 17 P17301,P01130,P53634,Q08722,P05067 5 +Regulation of cell killing 0.8398796485048698 2.430171809117195 0.0150916669556091 1.0 0.3318217100196115 10 P04439,P01889,O15400,P11279,Q92692 5 +Exocytic process 0.6770043874511116 2.427180399268127 0.0152166873327217 1.0 0.3318217100196115 22 O00161,Q8WU76,Q9H270,P51809,O95721,Q5SQN1,Q15833,Q7L0J3,Q9UEU0,P56545 10 +Hormone metabolic process 0.6053941174712618 2.4188987687357875 0.0155675719020114 1.0 0.3318217100196115 34 P42892,P07711,O95470,P07858,Q9HB40,P56937,O75787,O75844,P16870 9 +Negative regulation of peptidase activity 0.5889539344129229 2.4136620763853713 0.0157931020813022 1.0 0.3318217100196115 43 Q15392,P07858,Q92673,Q06481,Q6YHK3,P05067 6 +Regulation of response to wounding 0.650475848935232 2.4133915988558337 0.0158048284704981 1.0 0.3318217100196115 26 Q96G23,Q16625,Q04656,P10586,O94898,O14936,Q9Y6X5,Q6YHK3,P05556 9 +Myeloid leukocyte differentiation 0.5966560937433619 2.4099285633882195 0.015955644337172 1.0 0.3318217100196115 36 P29317,Q15904,P04062,P02786,Q6YHK3,P05067,Q86WC4 7 +Import across plasma membrane 0.6395197311621312 2.4089153303469573 0.0160000094459549 1.0 0.3318217100196115 28 Q8IWT6,P05556,P31751,Q9BXP2,Q9Y666,P08195,P55011,P11166,P30825,P05026,Q92581,P41440,Q15043,P98164 14 +Regulation of leukocyte mediated cytotoxicity 0.8526377116764619 2.404385231853914 0.0161996920083706 1.0 0.3318217100196115 9 P04439,P01889,O15400,P11279,Q92692 5 +Glial cell development 0.6484033170189079 2.400506274760663 0.0163724100497348 1.0 0.3318217100196115 26 P01130,Q07954,P15260,Q92542,P05067 5 +Collagen metabolic process 0.7612067269165093 2.3970642935079525 0.016527023495644 1.0 0.3318217100196115 14 Q9UBG0,P17301,P07711,P07858,Q32P28,Q92791 6 +Regulation of leukocyte migration 0.6371948972661461 2.394052758590916 0.0166633517045493 1.0 0.3318217100196115 28 Q99538,P17301,P14174,Q07021,Q00013,Q08722,O94813,P05067 8 +Regulation of lysosomal lumen ph 0.8875211459633746 2.3910270079936464 0.0168013168899925 1.0 0.3318217100196115 7 P50897,Q9NUM4,O75787,Q8N511,O75503 5 +Peptide catabolic process 0.7918299472558326 2.3869056390013808 0.0169908516803984 1.0 0.3318217100196115 12 P42892,Q9UIQ6,O14773 3 +Cellular response to thyroid hormone stimulus 0.9261987134787736 2.386184846442014 0.0170241917856663 1.0 0.3318217100196115 6 P07711 1 +Regulation of protein localization to plasma membrane 0.6066744091620393 2.3833027371350592 0.0171580774917912 1.0 0.3318217100196115 33 Q9BXS4,Q13501,P29317,Q9UNK0,P00533,O15400,Q07954,Q9UEU0 8 +Negative regulation of glycoprotein metabolic process 0.9516101543909972 2.3810165435712136 0.0172649365660857 1.0 0.3318217100196115 5 Q9BXS4,Q9Y287 2 +Astrocyte differentiation 0.722897729264905 2.3799570041865676 0.0173146581824383 1.0 0.3318217100196115 16 P01130,P15260,P05067 3 +Cytosolic transport 0.5065213168016672 2.376889554650108 0.0174593149115762 1.0 0.3318217100196115 72 Q99523,Q9P2R3,Q13614,Q9H270,Q9Y3E7,Q9UEU0,O75503,Q9BVK6,O75494,P33176,Q13190,O95249,Q96ED9,Q92673,O15260,Q4J6C6,Q8NBN3,P11279,Q93009,O43752,P51151,Q9UNK0,A4D1P6,Q9H3S7 24 +Glycoside metabolic process 0.8459480228498433 2.3759455752391885 0.017504044398813 1.0 0.3318217100196115 9 P04066,P06280,P08236,Q9BTY2 4 +Apoptotic cell clearance 0.827273833748492 2.375167784369345 0.0175409746739154 1.0 0.3318217100196115 10 Q8WTV0,Q08431,Q07954 3 +Membrane docking 0.5918703973225163 2.3700028672595197 0.0177879473139939 1.0 0.3318217100196115 35 Q9Y5Y5,O43752,Q86Y82,P51149,Q13190,Q9UNK0,Q9H270,O15400,Q8WU76,O95721,Q15833,Q8NEN9,Q9UEU0,O43865,P56545 15 +Microglial cell activation 0.9484867219443192 2.368976551025481 0.0178373843226882 1.0 0.3318217100196115 5 P05067,P15260,P53634 3 +Leukocyte migration 0.5685537058262846 2.3674857623169947 0.017909409105236 1.0 0.3318217100196115 51 Q99538,P35613,P17301,P14174,Q07021,Q00013,Q08722,Q4KMQ2,O94813,P04062,P78310,P05067,Q9Y624,P05556 14 +T cell mediated immunity 0.7546597064421062 2.3649276283341543 0.0180335945781724 1.0 0.3318217100196115 14 P04439,P01889,Q9BY67,P53634,O15400,Q92692 6 +Associative learning 0.7360866738280134 2.357172595648062 0.0184146857281299 1.0 0.3318217100196115 15 Q99538,P50897,O60266,P05067,Q13641 5 +Autophagosome maturation 0.6748036829055584 2.356990290612658 0.018423728570005 1.0 0.3318217100196115 21 P13473,Q9Y3E7,P51809,Q13137,Q9UEU0,Q8NHS3 6 +Regulation of long term synaptic potentiation 0.8791129573467628 2.3568208942481212 0.0184321345889317 1.0 0.3318217100196115 7 Q99538,Q13501,P05067 3 +Cell activation involved in immune response 0.5766236564233999 2.3562392593042034 0.018461022832545 1.0 0.3318217100196115 46 Q9NQZ7,Q04721,Q07954,Q9NRA0,Q04656,P13051,Q9Y2Y6,P02786,O00161,P51809,P11279,P05067,Q9UQ84 13 +Regulation of t cell proliferation 0.7015166446011755 2.3540597183178296 0.0185696275197553 1.0 0.3318217100196115 18 P04439,P10644,Q96J02,P02786,P30825,Q9HCL2 6 +Neurotransmitter secretion 0.6638306047989448 2.3498862275051255 0.0187791501164338 1.0 0.3318217100196115 22 Q4J6C6,P50897,O00161,Q06787,O14936,Q7L0J3,O95721,Q5SQN1,Q15833,P0DP25,P56545 11 +Regulation of cell activation 0.4972830537695569 2.3478901061993445 0.0188800907761474 1.0 0.3318217100196115 75 P14174,P07947,Q9Y624,Q9NRA0,P53634,Q96J02,P10644,P51809,Q5ZPR3,P01130,Q9NPF0,P04439,Q08722,P02786,P11279,Q14254,P30825,Q9HCL2,Q92692 19 +Natural killer cell mediated immunity 0.7829409434757492 2.3456199741602473 0.0189954641134735 1.0 0.3318217100196115 12 P04439,P01889,Q9BY67,P33176,P07437,P51809,P11279,Q92692 8 +Regulation of nervous system process 0.7159037174380368 2.343351974942931 0.0191113441732106 1.0 0.3318217100196115 16 P17301,P53634,Q9UQB8,Q9Y2Y6,P04062,Q06787,Q14118,P05067 8 +Positive regulation of cell junction assembly 0.7158923083718107 2.3432921226721923 0.0191144105875384 1.0 0.3318217100196115 16 P29317,O75955,Q9BQT9,P41440,O14786,Q13641 6 +Mononuclear cell migration 0.6473750502083366 2.337113777294397 0.0194332688290692 1.0 0.3318217100196115 24 Q99538,Q07021,Q08722,O94813,P04062,P05067,Q9Y624 7 +Sphingoid metabolic process 0.9133234749075688 2.335532744622022 0.0195156073805695 1.0 0.3318217100196115 6 P04062,O15269,Q13510,Q9NRA0 4 +Membrane biogenesis 0.6417673975891194 2.329997415147351 0.019806287735882 1.0 0.3318217100196115 25 Q86XL3,Q9Y5Y5,Q9H6H4,O75955,Q16739,P41440,Q96CP7,Q14254 8 +Iron ion transport 0.7788730380902109 2.3266535136087643 0.0199837138923915 1.0 0.3318217100196115 12 P02792,O15173,Q04656,P02786,Q15043 5 +Endosomal transport 0.511886118459334 2.3195522019632286 0.0203651140958811 1.0 0.3318217100196115 86 Q99523,Q9P2R3,Q13501,Q15904,Q9Y3E7,Q9H223,Q9UEU0,O75503,Q9H4M9,Q9BVK6,Q13190,O95249,Q92673,O15260,Q4J6C6,Q9C005,Q8NBN3,Q96L92,Q93009,O43752,P51151,Q9BRG1,Q92783,Q9H3S7,O14964 25 +Chloride transmembrane transport 0.8506860371267138 2.31673034572165 0.0205184254434094 1.0 0.3318217100196115 8 Q8IWT6,Q9UHG3,P51790,Q4KMQ2,Q9BXP2,P55011,P51798 7 +Vesicle docking 0.6858140755133402 2.31533056631864 0.0205948481914395 1.0 0.3318217100196115 19 O43752,Q86Y82,Q13190,Q9UNK0,Q9H270,O15400,Q15833,Q9UEU0,P56545 9 +Regulation of protein localization to membrane 0.5598750672807338 2.3150614122120476 0.0206095714215883 1.0 0.3318217100196115 52 Q9BXS4,P27105,Q13501,P29317,Q9UNK0,Q14118,O15400,P00533,Q07954,Q9UEU0,P05556 11 +Negative regulation of hydrolase activity 0.5107069009526938 2.3102284731063483 0.0208755084740512 1.0 0.3318217100196115 69 Q07954,Q99523,Q9NRA0,P07858,Q15392,Q92673,P04899,Q06481,Q6YHK3,P05067,Q15043,Q9Y624 12 +Organic acid transport 0.5472908389205418 2.3085764370700947 0.0209670967304222 1.0 0.3318217100196115 57 Q8IWT6,P05556,P14174,Q9H2D1,P31751,Q96QD8,P23786,Q9H2J7,O14678,Q9Y619,P08195,P55011,P11166,P30825,Q7L0J3,P41440,P98164,Q96NB2 18 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.6924968779013811 2.3048761642904636 0.0211735098962488 1.0 0.3318217100196115 18 Q92896,Q9NYA4,Q92673,Q6YHK3,Q07954,P98164 6 +Response to thyroid hormone 0.8292514580488197 2.304516697371848 0.0211936561429642 1.0 0.3318217100196115 9 P07711,P07858 2 +Intracellular lipid transport 0.6921960430572806 2.3032304616560646 0.0212658797811409 1.0 0.3318217100196115 18 P01130,P61916,P23786,Q9H2C2,O15118 5 +Positive regulation of long term synaptic potentiation 0.9302195554778432 2.2982303797813755 0.0215486804930991 1.0 0.3318217100196115 5 Q13501,P05067 2 +Regulated exocytosis 0.5759205833255727 2.296293980426708 0.0216590780582017 1.0 0.3318217100196115 41 Q4J6C6,Q9NRA0,Q15833,O00161,Q06787,O14936,P04899,P51809,O95721,Q5SQN1,P11279,P0DP25,Q7L0J3,O43760,P56545 15 +Amyloid precursor protein catabolic process 0.6985857682396623 2.293444607602351 0.0218224209692434 1.0 0.3318217100196115 17 Q92673,P15260,Q15392 3 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.5757514797712727 2.286423695066671 0.0222294834277083 1.0 0.3318217100196115 40 Q9NQZ7,P04439,P53634,P01889,Q9BY67,Q07021,P13051,Q9Y2Y6,P02786,O15400,Q9UQ84,Q92692 12 +Mating 0.926799419871936 2.284921864266143 0.0223174097478828 1.0 0.3318217100196115 5 P05067 1 +Axon development 0.5222062629224586 2.284814015583896 0.0223237354880632 1.0 0.3318217100196115 95 Q9P265,Q13740,O75955,Q14118,P05067,P51805,P35613,O15031,P33176,O94898,Q06481,Q96G23,Q8N0X7,P13591,Q9BVA1,P29317,P10586,O14786,P05556,Q13049,P42892,Q04721,Q92859,Q9UQB8,O94813,Q15375,P41440,Q92581,Q9Y6N7 29 +Sodium ion transport 0.6097310417224626 2.284792481459077 0.0223249987340432 1.0 0.3318217100196115 30 P27105,Q9H2J7,Q96QD8,Q4KMQ2,P08195,P55011,Q6P4Q7,P05026,Q92581,P46934,Q9Y6M7 11 +Cholesterol efflux 0.8244550990104194 2.283878997535129 0.0223786432736592 1.0 0.3318217100196115 9 Q8WTV0,P61916,O15118,Q07954 4 +Astrocyte development 0.8241480422258151 2.282555990343445 0.0224565358376349 1.0 0.3318217100196115 9 P01130,P15260,P05067 3 +Positive regulation of mononuclear cell migration 0.8234901174005381 2.2797204745960062 0.0226242721804934 1.0 0.3318217100196115 9 Q99538,P05067,Q07021,Q08722 4 +Toll like receptor 3 signaling pathway 0.8986689849407002 2.277510693827315 0.0227557467703467 1.0 0.3318217100196115 6 Q5KU26,O75955,Q6AZY7,P41440 4 +Interleukin 6 production 0.6955271865854773 2.2769838302492396 0.0227871912298571 1.0 0.3318217100196115 17 P04062,Q08722,P05067,P01889 4 +Lipoprotein metabolic process 0.6132819367001648 2.2729353882738863 0.0230300738484474 1.0 0.3318217100196115 29 Q9BQE5,P06756,P01130,P50897,Q8IUH4,P04062,Q16739 7 +Positive regulation of t cell proliferation 0.7856295283179832 2.2716808715954424 0.0231057923443571 1.0 0.3318217100196115 11 P02786,P04439,P30825 3 +Negative chemotaxis 0.9231182795698964 2.270575616283947 0.0231726809576111 1.0 0.3318217100196115 5 Q15375,P51805,O94813,Q9Y6N7 4 +Ganglioside catabolic process 0.975275463585056 2.2700456410064085 0.0232048139685543 1.0 0.3318217100196115 4 P06865,P07686,P17900 3 +Positive regulation of defense response 0.5636968886359639 2.2691893670162444 0.0232568125986443 1.0 0.3318217100196115 47 P17301,P01130,O43405,P53634,Q08722,P51809,P11279,P05067,Q92692 9 +Negative regulation of defense response 0.5760632226260027 2.2672370988869033 0.0233757456557375 1.0 0.3318217100196115 37 Q92485,P01130,P04439,P01889,Q07021,P04062,Q96J02,O43657 8 +Positive regulation of cell activation 0.5648902469557622 2.2656809316748254 0.0234709258610261 1.0 0.3318217100196115 46 Q9NPF0,P14174,P04439,Q9NRA0,P53634,Q9HCL2,Q08722,P02786,P51809,P30825,P11279,P07947,Q14254,Q92692 14 +Regulation of natural killer cell mediated immunity 0.8563587511016204 2.2635290020028855 0.0236030988855959 1.0 0.3318217100196115 7 P11279,P04439,Q92692,P01889 4 +Long term synaptic potentiation 0.8019257338014816 2.2633931701922614 0.0236114633979789 1.0 0.3318217100196115 10 Q99538,Q13501,Q92542,P05067 4 +Regulation of protein localization to cell periphery 0.572333053256936 2.260974119488135 0.0237608597270089 1.0 0.3318217100196115 40 Q9BXS4,Q13501,P29317,Q9UNK0,Q14118,O15400,P00533,P63096,Q07954,Q9UEU0,P05556 11 +Cellular response to amyloid beta 0.8368112477829229 2.2583602851809803 0.0239232066246135 1.0 0.3318217100196115 8 Q99538,P05067 2 +Response to amyloid beta 0.8368112477829229 2.2583602851809803 0.0239232066246135 1.0 0.3318217100196115 8 Q99538,P05067 2 +Lysosomal lumen acidification 0.8937886528636593 2.258100272922556 0.0239394086367419 1.0 0.3318217100196115 6 P50897,Q9NUM4,O75787,Q8N511,O75503 5 +Macrophage activation 0.7823188806430121 2.2565552585227695 0.0240358787490433 1.0 0.3318217100196115 11 P01130,P15260,P05067,P53634 4 +Regulation of phagocytosis 0.6563523819789958 2.249848694764777 0.0244585516961173 1.0 0.3318217100196115 21 P17301,P06756,Q08431,Q08722,Q06481,Q8WTV0 6 +Cardiac septum morphogenesis 0.834267507669569 2.247613574412452 0.0246008412350877 1.0 0.3318217100196115 8 P98164,O94813,Q9Y6N7,O14786 4 +Diol metabolic process 0.8341315407409843 2.247038749084807 0.0246375508049816 1.0 0.3318217100196115 8 P04062,Q13510,Q9NRA0 3 +Diol biosynthetic process 0.8341315407409843 2.247038749084807 0.0246375508049816 1.0 0.3318217100196115 8 P04062,Q13510,Q9NRA0 3 +Cellular ion homeostasis 0.5346825208738851 2.246337351260606 0.0246824078371179 1.0 0.3318217100196115 106 Q93050,Q15904,P51149,Q9NWW5,Q14344,Q9Y487,P55011,P05067,O75503,P06756,P50897,P51790,Q9H7F0,P07686,P17612,Q13772,P0DP25,Q9NQ11,P02792,Q9NUM4,Q9NWR8,P22413,O75787,Q04656,P98194,P02786,Q15043,Q7L0J3,P17252,Q8N511,Q8NEN9,Q92544,Q9HD20,Q92581,Q9Y3D6,P05026,Q05086,Q9Y6M7 38 +Intestinal absorption 0.8152006129942923 2.2439087607163395 0.0248382723647258 1.0 0.3318217100196115 9 P01130,Q8WTV0,Q16739 3 +Ganglioside metabolic process 0.9162563715729516 2.2437720842242523 0.0248470694063993 1.0 0.3318217100196115 5 P06865,P07686,P17900 3 +Astrocyte activation 0.9682880945982228 2.243327086954002 0.0248757298946156 1.0 0.3318217100196115 4 P01130,P15260,P05067 3 +Membrane protein proteolysis 0.7457933562253324 2.2428299962094256 0.0249077793634788 1.0 0.3318217100196115 13 O43847,P38159,Q16740,Q92542,Q14118,O94898 6 +Regulation of leukocyte chemotaxis 0.7137021802797009 2.242749847548492 0.0249129502208134 1.0 0.3318217100196115 15 Q99538,P14174,Q07021,Q00013,O94813 5 +Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii 0.9159566111746372 2.242599368697318 0.0249226609997852 1.0 0.3318217100196115 5 Q99538,P07711 2 +Aminoglycan biosynthetic process 0.7609017926841827 2.2423130331896064 0.0249411480034702 1.0 0.3318217100196115 12 O43505,P06865,Q9P2E5,Q8NCH0,Q7LGA3,Q8N6G5 6 +Antigen processing and presentation of endogenous antigen 0.8326786743484376 2.240893974164877 0.0250329436729881 1.0 0.3318217100196115 8 P10321,P04439 2 +Antigen processing and presentation of endogenous peptide antigen 0.8326786743484376 2.240893974164877 0.0250329436729881 1.0 0.3318217100196115 8 P10321,P04439 2 +Negative regulation of chemotaxis 0.8503506931559519 2.2387192582913924 0.0251741886632101 1.0 0.3318217100196115 7 P14174,O94813,Q9Y6N7,O14786 4 +Regulation of peptidyl tyrosine phosphorylation 0.5797393433593949 2.237856775026408 0.0252303965957134 1.0 0.3318217100196115 34 P14174,Q9H223,Q9BRG1,Q15375,P00533,O14786,P07947,Q9H2J4,P05067 9 +Digestive system process 0.7286972079191567 2.236178383475106 0.025340088602054 1.0 0.3318217100196115 14 P01130,Q8WTV0,Q16739 3 +Triglyceride metabolic process 0.7282745363410614 2.234064899086796 0.0254788031554131 1.0 0.3318217100196115 14 P01130,Q92673,Q9HCL2 3 +Sphingosine biosynthetic process 0.913531391978318 2.23310591380545 0.0255419607208771 1.0 0.3318217100196115 5 P04062,Q13510,Q9NRA0 3 +Leukocyte mediated immunity 0.5322774451547593 2.224970928220769 0.0260831898385305 1.0 0.3318217100196115 59 P04439,Q9NRA0,P53634,P01889,Q07021,P13051,P02786,O15400,P51809,P11279,Q9UQ84,Q92692 12 +Regulation of t cell mediated cytotoxicity 0.9111728431377382 2.223863935000564 0.0261576002002175 1.0 0.3318217100196115 5 P04439,Q92692,P01889 3 +Positive regulation of t cell mediated cytotoxicity 0.9111728431377382 2.223863935000564 0.0261576002002175 1.0 0.3318217100196115 5 P04439,Q92692,P01889 3 +Viral life cycle 0.538177109830526 2.223586552767009 0.0261762741247246 1.0 0.3318217100196115 110 P07711,P07858,Q14118,P00533,Q8WTV0,Q9Y624,P17301,P35613,P06756,Q96J02,Q14108,P56545,P01130,P13591,P29317,P02786,O14786,P11279,P46934,P05556,P27105,Q06787,P08195,P78310,O15118,Q92692 26 +Digestion 0.7099045851823356 2.223172384847503 0.0262041781802793 1.0 0.3318217100196115 15 P01130,Q8WTV0,Q16739 3 +Positive regulation of leukocyte migration 0.6930646020456032 2.2226176080975657 0.0262415958631114 1.0 0.3318217100196115 16 Q99538,P17301,Q07021,Q08722,P05067 5 +Mating behavior 0.9620179716374552 2.219289750293622 0.0264670184745066 1.0 0.3326439811898302 4 P05067 1 +Reproductive behavior 0.9620179716374552 2.219289750293622 0.0264670184745066 1.0 0.3326439811898302 4 P05067 1 +Learning 0.6320506066306296 2.2180563435445597 0.0265509909595258 1.0 0.3326439811898302 23 Q99538,P50897,O60266,P05067,Q13641,P05556 6 +Neuron recognition 0.8269785827517985 2.216741506095075 0.026640760727403 1.0 0.3326439811898302 8 P05067,Q9Y6N7,O14786 3 +Regulation of amyloid beta clearance 0.8833808304551599 2.216559456909426 0.0266532106682988 1.0 0.3326439811898302 6 Q07954,P15260 2 +Intracellular sterol transport 0.7543271486832828 2.2112323798231004 0.0270197492070607 1.0 0.3359672712165512 12 P01130,P61916,O15118 3 +Glial cell differentiation 0.5576500226632619 2.209312267299751 0.027152928520465 1.0 0.3360349770699964 46 P01130,Q07954,P15260,Q92542,P04062,P05067 6 +Inorganic anion transmembrane transport 0.7537009429192448 2.208265764227729 0.0272257523946595 1.0 0.3360349770699964 12 Q8IWT6,Q9UHG3,P51790,Q4KMQ2,Q9BXP2,Q9Y666,P55011,P51798 8 +Glycosylceramide metabolic process 0.8811264653883127 2.2075354123455653 0.027276675801539 1.0 0.3360446345991076 6 Q16739,P06280,O60512 3 +Regulation of biological process involved in symbiotic interaction 0.7882252845580288 2.20232338734754 0.0276424733096161 1.0 0.3368361020382676 10 Q92692,Q9BTY2 2 +Sodium ion transmembrane transport 0.6253307069878995 2.201245882232614 0.027718621751158 1.0 0.3371510035866807 24 P27105,Q9H2J7,P08195,Q6P4Q7,P05026,Q92581,P46934,Q9Y6M7 8 +Membrane invagination 0.6809390856497256 2.197999883999896 0.0279491142046401 1.0 0.3389990268390669 17 P17301,Q08431,P51790,Q4KMQ2,Q06481,P51809,O14964 7 +Neutral lipid biosynthetic process 0.8224446692032412 2.1974798056127924 0.0279861971816066 1.0 0.3389990268390669 8 Q8NCC3,P01130,Q9HCL2 3 +Macromolecule depalmitoylation 0.8399413848805009 2.195559824749122 0.0281234644766519 1.0 0.3389990268390669 7 Q9UMR5 1 +Regulation of cell junction assembly 0.5605533440506654 2.189387433983678 0.028568692207936 1.0 0.3431314967340271 42 P29317,O75955,Q9Y4F1,Q15375,Q9BQT9,Q13641,P05067,O14786,P41440,Q9Y624 10 +Transforming growth factor beta receptor signaling pathway 0.610107054000373 2.187722985981113 0.0286897866735678 1.0 0.3439694996176233 27 Q92896,Q9NYA4,Q9H3E2,Q06481,O00560,Q6YHK3 6 +Aorta development 0.7843756924747357 2.185080500610741 0.0288829446987359 1.0 0.3454433924917443 10 Q07954,P98164 2 +Neural precursor cell proliferation 0.5839313735970153 2.184486854923913 0.0289264921639695 1.0 0.3454433924917443 32 O95456,Q13418,Q8NEM2,O15031,P19022,Q15058,P55209,Q9UKA9,O75306,P04899,Q06481,Q8NCG7,P35222,Q9H0H5,P98164 15 +Plasma lipoprotein particle clearance 0.7181832284373407 2.1834382815785984 0.0290035493922948 1.0 0.3454433924917443 14 P01130,Q9H4M9,P61978,P38571,Q8WTV0,P35610,P98155 7 +Organic hydroxy compound transport 0.5616994327466251 2.181307380968601 0.029160688863536 1.0 0.3454433924917443 40 P01130,Q07954,Q86Y82,P61916,Q9H2C2,Q8WTV0,O15118 7 +Cell cell adhesion 0.553549540423797 2.18033398979958 0.0292327132951761 1.0 0.3454433924917443 124 Q9P273,Q13740,P23458,O75955,P00533,P07947,Q9Y624,P17301,Q14517,P35613,P06756,O15031,Q14168,P10644,Q96J02,Q9BQT9,O60716,Q5ZPR3,P04439,Q9BY67,Q14574,Q08722,P98194,P02786,P10586,Q92692,P07942,P61225,P31949,P41440,Q14254,O60245,P05556,Q14126,P17252,Q92859,Q96J84,Q9UQB8,O00192,Q6IQ23,O00592,Q15375,Q12959,P30825,P78310,Q9HCL2,Q9Y6N7 47 +Regulation of mononuclear cell migration 0.6767853171799122 2.1753664353471853 0.0296026676592882 1.0 0.3454500873270151 17 Q99538,Q07021,O94813,Q08722,P05067 5 +Embryonic digit morphogenesis 0.8730407428874403 2.17509232931046 0.0296231981729964 1.0 0.3454500873270151 6 P42892,Q9NX62 2 +Phospholipid transport 0.6520453590420232 2.1730052752086593 0.0297799202546784 1.0 0.3462049689246365 20 P01130,Q7Z3C6,P61916,Q9NV96,Q8WTV0,Q14108 6 +Positive regulation of chemotaxis 0.6598716201203326 2.169529555453951 0.0300425030079218 1.0 0.3468549604647691 19 Q99538,P17301,Q07021,O94813,O14786,Q13641 6 +Amyloid precursor protein biosynthetic process 0.8973364435329021 2.169457737062527 0.0300479496424426 1.0 0.3468549604647691 5 Q9NQX7,Q9Y287 2 +Vitamin d metabolic process 0.948919437857496 2.1688886824015716 0.0300911361872913 1.0 0.3468549604647691 4 Q99538,P98164 2 +Amyloid beta metabolic process 0.6993482498219787 2.1684982474459416 0.0301207978201276 1.0 0.3468549604647691 15 Q92673,P15260 2 +Nervous system process 0.5507050139600548 2.1661657115443744 0.030298526275762 1.0 0.34830312710147 123 O14773,Q13614,Q9NWW5,P04062,Q14118,P00533,P18887,Q9H6K4,P05067,P17900,P98155,Q99538,P17301,P50897,O43405,P53634,P10253,Q14168,P07686,Q9Y2Y6,O94898,O60266,Q14108,Q96KQ7,Q13641,P98164,P01130,O75844,O43164,Q6P4Q7,P05556,Q9Y6M9,Q99808,Q9UQB8,Q92542,Q06787,Q05086 37 +Neuron death 0.4852295143653928 2.163459076153865 0.0305058880587252 1.0 0.3500864071396857 79 Q99538,Q04446,P50897,Q9NR28,Q15392,O95831,Q9UL15,Q92542,P31751,Q15375,Q92673,P04062,O14786,P05067,Q9NQ11 15 +Zymogen activation 0.7616574353717368 2.1615075935732726 0.0306561510154812 1.0 0.3501553220153625 11 Q99538,P07711 2 +Import into cell 0.5608854948432758 2.1613458667634493 0.0306686323519871 1.0 0.3501553220153625 38 Q8IWT6,P05556,Q99808,P31751,Q9BXP2,O75955,P08195,P55011,P11166,P30825,P05026,Q92581,P41440,Q15043,P98164 15 +Amyloid beta formation 0.7279293944700855 2.1556785198115977 0.0311087765859088 1.0 0.354129238336245 13 Q92673,P15260 2 +Neuropeptide signaling pathway 0.8676662678674131 2.1534616696127973 0.0312824134073213 1.0 0.3547457439185573 6 Q99523,Q92673 2 +Cell chemotaxis 0.556657322789763 2.1510898529302973 0.0314691082628957 1.0 0.3552921838355208 41 Q99538,P35613,P14174,Q07021,P29317,P33527,Q00013,Q4KMQ2,O94813,P55011,O14786,P78310,Q13641 13 +Response to copper ion 0.7933629900580429 2.148805169156629 0.0316498474770499 1.0 0.3556577467516846 9 P02786,P19021,P05067 3 +Entry of bacterium into host cell 0.8918898315313868 2.1479531751531935 0.0317174754508875 1.0 0.3556577467516846 5 Q9BTY2 1 +Glycerophospholipid catabolic process 0.7760437698297925 2.147635178570941 0.0317427485204486 1.0 0.3556577467516846 10 Q8NCC3,P01130 2 +Synaptic vesicle exocytosis 0.663580727900396 2.1451146264220653 0.0319436832756414 1.0 0.3556577467516846 18 Q4J6C6,O00161,Q06787,O14936,Q7L0J3,O95721,Q5SQN1,P0DP25,P54920,P56545 10 +Cardiac septum development 0.6940132679046929 2.1407244195020967 0.032296268064994 1.0 0.3576513556972093 15 Q9Y6N7,O94813,P98164,O14786 4 +Regulation of gliogenesis 0.6703535080798628 2.1401937638404274 0.0323391109448685 1.0 0.3576513556972093 17 P01130,Q14118,P98164 3 +Response to ph 0.8072750086066965 2.1327077058524195 0.0329487113895357 1.0 0.3631945127182044 8 Q99538,P04062,P19021 3 +Ensheathment of neurons 0.5813832901673082 2.1289155663412824 0.0332612466536612 1.0 0.3648394027378686 31 P53634,Q15058,Q92542,P31751,P42345,Q13614,Q9Y2Y6,P07686,Q14118,Q12959,O15228,O75882 12 +Glucose import 0.6899648073349686 2.119584159196792 0.0340411295323814 1.0 0.3687361501788327 15 Q99523,Q16625,Q06481,P11166 4 +Membrane protein ectodomain proteolysis 0.7525464145686803 2.1192374452452176 0.034070405228374 1.0 0.3687361501788327 11 O43847,P38159,Q92542,Q14118,O94898 5 +Proteoglycan biosynthetic process 0.7347597627622457 2.1180117933131797 0.0341740689171889 1.0 0.3687361501788327 12 Q8WVQ1,Q9P2E5,Q99805,Q8NCH0,Q7LGA3,Q8N6G5 6 +Positive regulation of autophagy 0.563039582777868 2.117818906611825 0.0341904074928187 1.0 0.3687361501788327 34 Q9BXS4,P21796,P27544,O15269,Q13137,Q13049 6 +Response to hepatocyte growth factor 0.786186277547317 2.1173086182614123 0.0342336639490852 1.0 0.3687361501788327 9 Q99538,Q06481 2 +Antigen processing and presentation of exogenous peptide antigen via mhc class ii 0.935396123520903 2.1165917690820626 0.0342945092826845 1.0 0.3687361501788327 4 Q99538,P07711 2 +Transepithelial transport 0.8208714362560681 2.115915488724396 0.0343519958738256 1.0 0.3687361501788327 7 P33527,Q86WC4,P55011,P78310,P51798,O43865 6 +Regulation of response to biotic stimulus 0.4741197499633098 2.115139318897019 0.0344180749390115 1.0 0.3687361501788327 75 P14174,O43405,P04439,P01889,Q07021,O75844,Q96J02,O43657,Q06481,P11279,Q92692 11 +Dendrite morphogenesis 0.5566779739435372 2.1149218683342617 0.0344366070132824 1.0 0.3687361501788327 35 Q9NUM4,Q9Y4F1,O14786,Q9ULH0,P46934,Q13641,P05556,P98155 8 +Positive regulation of nervous system development 0.5390613178232234 2.1144848164019354 0.0344738802512429 1.0 0.3687361501788327 50 Q16706,O15031,P55209,O94813,Q14118,Q9BQT9,O14786,Q9Y6N7,P51805,Q13641,P98164,Q13049 12 +Cell volume homeostasis 0.8029657291283404 2.114216246523702 0.0344968018743849 1.0 0.3687361501788327 8 Q8IWT6,P51790,Q4KMQ2,Q9BXP2,Q9Y666,P55011 6 +Platelet derived growth factor receptor signaling pathway 0.7336759144801925 2.1128167200044907 0.0346164580259011 1.0 0.3694259581044423 12 Q07954,O94898,O95470,O14786 4 +Retrograde transport endosome to golgi 0.5555627908463179 2.1109858318644927 0.0347735296776026 1.0 0.3705122351340106 36 Q4J6C6,Q9BVK6,O43752,Q9P2R3,P51151,Q13190,O95249,Q8NBN3,O15260,Q9UEU0,O75503,Q93009 12 +Vascular process in circulatory system 0.5532021500572775 2.1101372029343266 0.0348465396336075 1.0 0.3705313926167805 39 P42892,Q9HB40,Q16625,Q96QD8,O94813,P02786,P30825,P41440,Q07954,P98164 10 +Carbohydrate transmembrane transport 0.6572062591894933 2.109463572631552 0.0349045871151363 1.0 0.3705313926167805 18 Q99523,Q16625,P31751,Q06481,P11166 5 +Cytokine production 0.5392135035966544 2.108399190452925 0.0349964744145661 1.0 0.3705313926167805 119 P14174,P01889,P15260,O43823,P04062,O75955,Q9Y6M1,P05067,Q9Y624,Q8IV08,P06756,Q9NRA0,Q07021,Q96J02,Q92673,Q06481,Q7KYR7,Q5ZPR3,Q96RD7,P04439,P31483,Q9BY67,P29317,O75787,Q08722,Q13049,P41440,Q9HCL2 28 +Memory 0.7493205728639506 2.104218776503795 0.035359367381651 1.0 0.3737830917852132 11 Q99538,P01130,P98155 3 +Negative regulation of cytokine production 0.5607926440643903 2.1015337748343295 0.0355941363667782 1.0 0.3750816068084082 34 P31483,Q07021,P29317,O43823,P04062,Q96J02,Q06481 7 +Cellular response to estradiol stimulus 0.8170961585841567 2.1000600939966714 0.03572355515904 1.0 0.3755928530058244 7 P17301,O95831,P00533 3 +Negative regulation of developmental growth 0.7015596107812577 2.099337949329714 0.0357871203633892 1.0 0.3755928530058244 14 Q99538,Q15375,P51805,O14786 4 +Neuron maturation 0.8540161421077628 2.098287273806415 0.035879776038729 1.0 0.3757285297055658 6 P05067 1 +Receptor recycling 0.7816501776434565 2.097339262805965 0.0359635535514117 1.0 0.3760183087387859 9 P01130,Q92673 2 +Basement membrane organization 0.7783909883472394 2.082961780161456 0.037254707481471 1.0 0.3854492692295514 9 Q14118,P14543,P05556 3 +Amino acid transport 0.6061172194584947 2.0809307880375827 0.0374402415900976 1.0 0.3854492692295514 24 Q9H2J7,Q96QD8,Q9Y619,P08195,P55011,P30825,Q7L0J3,P05556,Q96NB2 9 +Osteoclast differentiation 0.6978199993659512 2.080298109718248 0.0374981980808217 1.0 0.3854492692295514 14 P29317,Q15904,P02786,Q6YHK3,Q86WC4 5 +Positive regulation of exocytosis 0.6433055194335348 2.0750214551038866 0.0379845463592425 1.0 0.3892544796630633 19 Q9NRA0,P51151,Q92783,P51809,O00560,P11279,Q9NQ11 7 +Cell adhesion mediated by integrin 0.758288633268275 2.067267085897309 0.038708993881962 1.0 0.3942669863174917 10 P17301,P29317,P06756,O00592 4 +Cell morphogenesis involved in neuron differentiation 0.5264825515694784 2.0664205092679455 0.0387887910348461 1.0 0.3944802390220617 113 Q9P265,O75955,Q14118,P05067,P51805,Q9ULH0,P98155,P35613,Q06481,Q13641,P13591,Q9NUM4,P29317,Q9Y4F1,O14786,P46934,P05556,P42892,Q04721,Q92859,O94813,Q15375,P41440,Q92581,Q05086,Q9Y6N7 26 +Regulation of exocytosis 0.5392139155245221 2.0640664045708186 0.0390114207444469 1.0 0.3947319038869248 46 Q4J6C6,P11233,Q9NRA0,Q15833,P51151,P51149,Q06787,O14936,Q9Y3E7,P04899,P51809,Q92783,P11279,P0DP25,O00560,Q9NQ11,O14964 17 +Negative regulation of neuron projection development 0.6021740823043629 2.056017960497279 0.0397807850329299 1.0 0.3991179959441562 24 Q96G23,Q9P265,Q9UL15,Q9NQX7,Q15375,O94898,O14786,P51805,Q05086,P08670 10 +Response to mitochondrial depolarisation 0.7716593196761807 2.0531878947268596 0.0400543579950265 1.0 0.4004022384605893 9 Q13501 1 +Membrane raft organization 0.7550645099567971 2.0525895141682655 0.0401124053774888 1.0 0.4004022384605893 10 O75955,O15118,P50897,P41440 4 +Leukocyte chemotaxis 0.5892340799804014 2.051436477520626 0.0402244597768568 1.0 0.4004022384605893 27 Q99538,P35613,P14174,Q07021,Q00013,O94813,Q4KMQ2,P55011,P78310 9 +Pulmonary valve development 0.9185868677056784 2.051223736143862 0.0402451633910594 1.0 0.4004022384605893 4 O94813,Q9Y6N7 2 +Regulation of pinocytosis 0.9182789472867772 2.0500225844319133 0.0403622269823829 1.0 0.4004022384605893 4 P50897 1 +Positive regulation of pinocytosis 0.9182789472867772 2.0500225844319133 0.0403622269823829 1.0 0.4004022384605893 4 P50897 1 +Cytokine production involved in inflammatory response 0.7879637981230825 2.049526519573122 0.0404106573721789 1.0 0.4004022384605893 8 Q8IV08 1 +Transcytosis 0.7543119641716471 2.0491599083767595 0.0404464809665501 1.0 0.4004022384605893 10 P55899,P98164 2 +Defense response to gram positive bacterium 0.8666346312007209 2.0475970430043944 0.0405994993359095 1.0 0.4013242544974423 5 P04439 1 +Vacuolar localization 0.6295653822576269 2.0419545425702923 0.0411560406636068 1.0 0.4036362841891224 20 Q9NUM4,Q9NRA0,Q86YV9,O00161,P51809,Q15833 6 +Nerve development 0.7358653339093486 2.0412783172445885 0.0412231710119377 1.0 0.4036362841891224 11 P42892,Q14118,P51805,O14786 4 +Negative regulation of growth 0.5460653125147701 2.040328386584928 0.0413176293242727 1.0 0.4036362841891224 36 Q99538,P50897,Q9NRA0,O94813,Q15375,O14786,P51805 7 +Synapse assembly 0.5995919824953685 2.0396632285392284 0.0413838797528096 1.0 0.4036362841891224 24 Q15375,Q9Y4F1,Q9BQT9,O00560,P05067,Q13641 6 +Carbohydrate transport 0.6204352476086398 2.03709568123573 0.0416404546139936 1.0 0.4036362841891224 21 Q99523,Q16625,P31751,Q06481,P11166 5 +Myotube differentiation 0.6582579969758476 2.0350355007742977 0.041847301020188 1.0 0.4036362841891224 16 Q99523,Q8IV08,O75955,P41440,P05556 5 +Glycosyl compound catabolic process 0.7341339480518949 2.03314458211975 0.042037917989258 1.0 0.4036362841891224 11 Q9BTY2,P06280,P08236,Q9Y6X5,P04066 5 +Salivary gland development 0.9136025948380432 2.0317646277754924 0.0421774897285063 1.0 0.4043970474398417 4 Q14118,O14786 2 +Connective tissue development 0.5815164816898588 2.029687690215577 0.0423882949535727 1.0 0.4049975912314467 28 Q92896,O15173,Q04656,Q9NX62,O75844,Q92673,Q15043,P35610 8 +Positive regulation of regulated secretory pathway 0.836982075073098 2.028961447520285 0.0424622172034094 1.0 0.4049975912314467 6 P11279,Q9NRA0 2 +Regulation of triglyceride metabolic process 0.8619255127126584 2.028768822786297 0.0424818422315289 1.0 0.4049975912314467 5 P01130,Q92673,Q8WTV0 3 +Response to manganese ion 0.7996707509245404 2.0265007047329933 0.0427135005826633 1.0 0.4060508949007227 7 P02786,Q9NQ11,P05067 3 +Appendage development 0.6417405381461109 2.0223124628172897 0.0431440819178521 1.0 0.4088737449920022 18 P42892,P19021,Q5SZK8,Q9NX62 4 +Positive regulation of protein localization to membrane 0.5554228486862575 2.021834364243134 0.0431934663465141 1.0 0.4088737449920022 33 P27105,Q13501,P29317,P33176,P31751,P98194,Q12959,P00533,Q07954,P05556 10 +Regulation of synapse assembly 0.7315849171203092 2.0211553028312386 0.0432636910108916 1.0 0.4089608704583864 11 Q15375,Q9BQT9,P05067,Q13641 4 +Positive regulation of leukocyte degranulation 0.8586051571017153 2.0154716225199074 0.0438552565102621 1.0 0.4125546266999527 5 P11279,Q9NRA0 2 +Tumor necrosis factor superfamily cytokine production 0.599325453129105 2.015062954549513 0.0438980531917632 1.0 0.4125546266999527 23 P14174,Q9NRA0,P15260,O43823,Q08722,P05067 6 +Positive regulation of tumor necrosis factor superfamily cytokine production 0.6543632707989859 2.0137739286987424 0.0440332741391262 1.0 0.4125546266999527 16 P05067,P15260,P14174 3 +Activated t cell proliferation 0.8332258130369823 2.013603912965786 0.0440511352914945 1.0 0.4125546266999527 6 P10644,Q9HCL2 2 +Positive regulation of endocytosis 0.5914421964387946 2.0120226206274494 0.0442175525215655 1.0 0.4133138591346337 25 P17301,P50897,O75955,Q06787,Q06481,P41440,Q07954 7 +Regulation of monocyte chemotaxis 0.8574763029400498 2.010946788616151 0.0443310775174798 1.0 0.4137978851283429 5 Q99538,O94813 2 +Multivesicular body sorting pathway 0.7280994811738909 2.0047339367581527 0.0449914984232073 1.0 0.4170581223130509 11 Q9UK41,Q99523,Q9BRG1,Q92783,Q9Y3E7,Q9H3S7 6 +Endosome transport via multivesicular body sorting pathway 0.7280994811738909 2.0047339367581527 0.0449914984232073 1.0 0.4170581223130509 11 Q9UK41,Q99523,Q9BRG1,Q92783,Q9Y3E7,Q9H3S7 6 +Golgi to vacuole transport 0.7768823512614584 2.0014287559774564 0.0453462043348906 1.0 0.4191865675206031 8 P11279,Q99523 2 +Response to transforming growth factor beta 0.5401211836649142 2.0001375410618567 0.0454854139892411 1.0 0.4198553512388177 37 Q92896,Q9NYA4,Q9H3E2,Q06481,O00560,Q6YHK3,P05556 7 +Autophagosome organization 0.552342447848443 1.9995965787420311 0.0455438436810833 1.0 0.4198553512388177 33 Q7Z3C6,P53365,Q86Y82,P51149,P04062,P60520,Q9NQ11,Q6PHR2,Q8TDY2,Q96KQ7,Q9H0U4,P16615 12 +Nucleotide transport 0.667056546971422 1.9989173271843 0.0456172996426726 1.0 0.419954865666473 15 Q99808,Q9H2D1,Q8TB61,Q08722,P41440 5 +Blood vessel endothelial cell migration 0.5811360467813225 1.9979489999581208 0.0457221895484227 1.0 0.4203430923916728 27 P42785,P29317,O94813,O14786,Q8WTV0,Q9Y6N7,P05556 7 +Phagocytosis recognition 0.904608802344184 1.9965652782395165 0.0458724278771778 1.0 0.4211465912778709 4 Q5KU26,Q08431 2 +Neutrophil migration 0.6659304810470456 1.992940044384697 0.0462680127124957 1.0 0.422712390251151 15 P35613,Q07021,O94813,P78310 4 +Mitophagy 0.6434379828573676 1.9913290490293292 0.0464447238560887 1.0 0.4227647230503173 17 P53365,Q13501,P21796 3 +Pinocytosis 0.7913551185484826 1.9911802685246665 0.0464610723076774 1.0 0.4227647230503173 7 Q06481,P50897 2 +Positive regulation of b cell proliferation 0.8520901181944207 1.9893289219187609 0.0466649093661493 1.0 0.4232046313557952 5 P02786,Q9NPF0 2 +Cellular carbohydrate metabolic process 0.4637341626170689 1.9883422340394925 0.0467738528277561 1.0 0.4233968183681783 73 P43304,O43505,Q04446,P16278,P31751,Q9NX62,P10253,O75844,Q8TDY2,Q7LGA3,Q93100,P08236,P48735,Q14108,Q8N6G5 15 +Regulation of platelet derived growth factor receptor signaling pathway 0.8269753709030319 1.9879931246114837 0.0468124503746374 1.0 0.4233968183681783 6 Q07954,O94898 2 +Regulation of regulated secretory pathway 0.6121100155794353 1.9869801270848233 0.0469245991444944 1.0 0.4238391690921855 21 Q4J6C6,Q9NRA0,Q15833,Q06787,O14936,P04899,P51809,P11279,P0DP25 9 +Regulation of peptidase activity 0.4858479080271664 1.9822629784412729 0.0474498152530422 1.0 0.4262850694717013 91 Q99538,Q07954,O43847,Q9NR28,P07858,Q15392,O95831,Q92542,Q15375,Q92673,Q06481,Q6YHK3,P05067,Q9NQ11,Q9Y6N7 15 +Substrate dependent cell migration cell extension 0.849571423362126 1.979204017355514 0.0477930408043705 1.0 0.4282205340519936 5 O00560 1 +Neutrophil chemotaxis 0.7058443848025435 1.9782791544141196 0.0478972234091279 1.0 0.4285810297569766 12 P35613,Q07021,O94813,P78310 4 +Glycosphingolipid biosynthetic process 0.8997292546859336 1.977421903623258 0.0479939601128123 1.0 0.4288740275680909 4 Q16739,O60512 2 +Regulation of entry of bacterium into host cell 0.898760996761661 1.9736194310374533 0.0484250325988986 1.0 0.4313118600452684 4 Q9BTY2 1 +Protein localization to membrane raft 0.898683149690942 1.973313660994534 0.0484598374536089 1.0 0.4313118600452684 4 O75955,Q14254,P41440 3 +Synaptic vesicle priming 0.8475806451613009 1.971194138058884 0.048701674171304 1.0 0.4320694749021072 5 Q7L0J3,O95721,O00161,Q5SQN1 4 +Negative regulation of cell projection organization 0.5429457886193574 1.971041901226559 0.0487190832692863 1.0 0.4320694749021072 34 Q96G23,Q9P265,Q9NQX7,O94813,Q15375,O94898,O14786,P51805,Q05086 9 +Cell killing 0.5921084527856423 1.9696121918633367 0.0488828332927413 1.0 0.4320694749021072 23 P04439,P53634,P01889,O15400,P51809,P11279,Q92692 7 +Heterotypic cell cell adhesion 0.7039495102775614 1.9690398475790043 0.0489485154235349 1.0 0.4320694749021072 12 P06756,Q08722,O75955,P78310,P41440,Q14254,P05556 7 +Response to leptin 0.8967735859744426 1.965810678674817 0.0493204838180014 1.0 0.4320694749021072 4 P98164 1 +Regulation of metallopeptidase activity 0.8459708423516386 1.9647125098552745 0.0494475212249949 1.0 0.4320694749021072 5 Q92673 1 +Peptidyl tyrosine modification 0.5223257898193628 1.9639261003675672 0.0495386625376443 1.0 0.4323022348011623 49 P14174,Q9H223,P29317,Q9BRG1,P23458,Q15375,P00533,O14786,P07947,Q9H2J4,P05067 11 +Regulation of jnk cascade 0.6081273164397006 1.962898027888304 0.0496580239841171 1.0 0.4327803338641781 21 Q96J02,P00533,O95819,O00560,P05067,Q8TDY2 6 +Collagen catabolic process 0.8450021584781047 1.960810272833469 0.0499011592510041 1.0 0.4337711664075612 5 P07711,P07858 2 +Camera type eye morphogenesis 0.6596316054244072 1.95942565324145 0.0500629588260115 1.0 0.4342542266914408 15 Q04721,Q14517,Q9P273,P54802,P29317 5 +Leukocyte differentiation 0.4573414292600551 1.9590701788488467 0.0501045686244379 1.0 0.4342542266914408 74 Q9NQZ7,Q04721,P07711,P01889,P29317,Q15904,Q04656,P04062,P24390,P02786,Q6YHK3,P05067,Q86WC4,P05556 14 +Negative regulation of axonogenesis 0.7670824820878217 1.95867282579852 0.0501511148103812 1.0 0.4342542266914408 8 P51805,Q15375,Q9P265,O14786 4 +Golgi to lysosome transport 0.844284306211015 1.957917526694521 0.0502396909530387 1.0 0.4344598822803425 5 P11279 1 +Polysaccharide metabolic process 0.5866286569870236 1.95706353227297 0.0503399992896747 1.0 0.4344766020029061 24 O43505,P31751,P10253,Q7LGA3,Q93100,Q8TDY2,Q8N6G5 7 +Gland morphogenesis 0.6590209006339799 1.9561691304777389 0.050445233676422 1.0 0.4344766020029061 15 Q04721,P29317,O14786,Q14118 4 +Embryonic appendage morphogenesis 0.7177313937817342 1.9556963414197588 0.0505009359833279 1.0 0.4344766020029061 11 P42892,Q5SZK8,Q9NX62 3 +Regulation of cell shape 0.5406340944360982 1.9539899163435657 0.0507024097177912 1.0 0.435245891008441 34 O43405,O15031,Q9UQB8,Q8WWQ0,O75844,Q14344,Q14118,P07686,Q12959,P46108,P51805,Q9Y624 12 +Regulation of immune effector process 0.5157572571737863 1.9514893807960525 0.0509988582205711 1.0 0.4370771710924141 52 P14174,P04439,Q9NRA0,P01889,Q07021,Q08722,P02786,O15400,Q06481,P51809,P11279,Q92692 12 +Eye morphogenesis 0.6215701351102965 1.9493453855775853 0.0512541919652553 1.0 0.4379974275417155 19 Q04721,Q14517,Q9P273,P54802,P29317 5 +Regulation of phosphatidylcholine metabolic process 0.8417707783403992 1.9477823004580632 0.0514410174967947 1.0 0.4379974275417155 5 P01130 1 +Negative regulation of toll like receptor signaling pathway 0.8417127540986404 1.9475482135470972 0.05146904541628 1.0 0.4379974275417155 5 Q92485,Q9NPR9 2 +Positive regulation of leukocyte cell cell adhesion 0.5813007534180236 1.9464253245900571 0.0516036700108224 1.0 0.4379974275417155 25 P04439,Q9HCL2,Q08722,P02786,P30825,P07947,Q14254 7 +Glutamate receptor signaling pathway 0.8916957807041017 1.945835540444608 0.051674497944925 1.0 0.4379974275417155 4 Q06787,Q92542,P05067 3 +Regulation of endocytosis 0.5027159980564149 1.9448598644771184 0.051791846715635 1.0 0.4379974275417155 58 P17301,Q07954,P06756,P50897,Q9UKS6,O75955,Q06787,Q06481,O00560,P41440,Q9H223,P05067 12 +Triglyceride biosynthetic process 0.7803447405943804 1.9442000929321517 0.0518713265957939 1.0 0.4379974275417155 7 P01130,Q9HCL2 2 +Deoxyribose phosphate catabolic process 0.7801385994497523 1.9433181982382377 0.0519777240429351 1.0 0.4379974275417155 7 Q9H773 1 +Regulation of neural precursor cell proliferation 0.6414611144566897 1.9429479389687017 0.0520224488846707 1.0 0.4379974275417155 16 Q13418,Q8NEM2,P19022,Q9UKA9,P55209,P04899,Q06481,P35222,P98164 9 +Protein localization to cell periphery 0.4908646941127166 1.9421837572464145 0.0521148587088244 1.0 0.4379974275417155 97 Q9BXS4,Q13501,Q15904,O75955,Q14118,P00533,O15400,P63096,Q9H223,Q9UEU0,Q9Y624,P35613,Q9H4M9,Q13641,Q4J6C6,P29317,Q14254,P05556,P31751,Q9UNK0,P41440,Q07954,P05026 23 +Positive regulation of mast cell activation 0.890468168493185 1.9410012225898452 0.0522581290779169 1.0 0.4379974275417155 4 Q9NRA0,Q92692 2 +Cerebellar purkinje cell layer development 0.7301323171740718 1.938221793644127 0.0525961689676881 1.0 0.4379974275417155 10 Q04656,P04062,P54802,Q7Z4L5 4 +Bone remodeling 0.7140204162843521 1.9380760028887265 0.05261395067919 1.0 0.4379974275417155 11 Q04721,O14773,P29317,P02786 4 +O glycan processing 0.7787453814567608 1.9373556387875543 0.0527018853521452 1.0 0.4379974275417155 7 Q86SF2,Q10472,O43505,Q10471 4 +Regulation of epidermal growth factor activated receptor activity 0.838174527131329 1.9332639838208312 0.0532036862053113 1.0 0.438815569565758 5 P05067 1 +Vesicle organization 0.5045594218948525 1.9332233705674315 0.0532086869535131 1.0 0.438815569565758 107 Q99523,O14964,Q9P2R3,Q13501,Q9BTU6,P51149,Q9H270,Q8WUH2,O15400,Q9Y3E7,Q9UEU0,Q9BVK6,P51790,Q13190,O95249,Q96ED9,P51809,O95721,Q14108,Q9NQ11,Q9UK41,Q9H9H4,Q9H4A6,P08754,Q86Y82,Q9NR31,Q5SQN1,O15027,O14653,O43752,Q8TCG2,Q12768,P31751,Q9BRG1,O00161,Q9UNK0,Q92783,O00560,Q92692 39 +Regulation of membrane lipid distribution 0.7287661082740289 1.9319106425242545 0.0533705359779668 1.0 0.438815569565758 10 Q7Z3C6,P33527,Q4KMQ2,Q9H2C2,Q9NV96,Q96CP7 6 +Negative regulation of response to cytokine stimulus 0.8376781015911037 1.9312582899545732 0.0534511187264143 1.0 0.438815569565758 5 O94813 1 +Neuron projection arborization 0.7439287127340778 1.9294323404012763 0.0536772120707542 1.0 0.438815569565758 9 Q13641,P98164,O14786 3 +Positive regulation of small gtpase mediated signal transduction 0.7281686345079517 1.9291492000184056 0.0537123425829308 1.0 0.438815569565758 10 Q04721,P06756,Q9Y624,Q9Y6N7 4 +Semaphorin plexin signaling pathway involved in neuron projection guidance 0.8868583714055301 1.9267744418702413 0.0540077459514329 1.0 0.438815569565758 4 P42892,P51805,O14786 3 +Regulation of wound healing 0.6248820964329628 1.9262534348790743 0.0540727366500239 1.0 0.438815569565758 18 Q16625,Q4KMQ2,O14936,P46108,Q9Y6X5,Q6YHK3,P55011,P05556 8 +Specification of animal organ identity 0.886440458177598 1.9251262805813716 0.0542135618621975 1.0 0.438815569565758 4 P98164 1 +Lymphocyte activation involved in immune response 0.5518591813788724 1.9225632974526463 0.0545349170913951 1.0 0.4408842151345358 31 Q9NQZ7,Q04721,P13051,Q04656,P02786,P51809,P11279,Q9UQ84 8 +Regulation of toll like receptor 3 signaling pathway 0.8844257019200259 1.9171773250044053 0.05521540771665 1.0 0.4432066217200517 4 O75955,P41440 2 +Positive regulation of lymphocyte mediated immunity 0.6005817471620186 1.9170816695152864 0.0552275569853117 1.0 0.4432066217200517 21 P04439,P01889,P02786,O15400,P11279,Q92692 6 +Lymphocyte activation 0.5043113315015647 1.9162692430342383 0.0553308336801205 1.0 0.4432066217200517 108 P07711,P14174,P04062,P07947,Q9NQZ7,Q9Y2Y6,P10644,P24390,Q96J02,P51809,Q9NPF0,P04439,Q9BY67,Q08722,P13051,Q04656,P02786,P11279,Q9UQ84,Q14254,P05556,Q04721,Q92542,P30825,P78310,Q9HCL2 26 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.7571803718205661 1.9152618851720191 0.0554591137752162 1.0 0.4432066217200517 8 P67809,O60506 2 +Crd mediated mrna stabilization 0.7571803718205661 1.9152618851720191 0.0554591137752162 1.0 0.4432066217200517 8 P67809,O60506 2 +Positive regulation of smooth muscle cell migration 0.8092696341171227 1.915070676549796 0.0554834908420058 1.0 0.4432066217200517 6 P17301,P31949,Q04656,O14786 4 +Motor neuron axon guidance 0.7568954861223964 1.9140098529747152 0.0556188968054531 1.0 0.4432316841737779 8 P51805,O94813,O14786 3 +Positive regulation of t cell mediated immunity 0.7398894410043066 1.9112586212952252 0.0559713537941819 1.0 0.4455107044282748 9 O15400,P04439,Q92692,P01889 4 +Regulation of t cell mediated immunity 0.7239890193769265 1.9098072058249205 0.0561580411677513 1.0 0.4464664198176389 10 O15400,P04439,Q92692,P01889 4 +Chondroitin sulfate proteoglycan metabolic process 0.8077559381766094 1.908811004053096 0.0562864768108379 1.0 0.4469573075666305 6 Q9P2E5,Q8N6G5,Q9NX62 3 +Chaperone mediated autophagy 0.7553400135841187 1.907170734828496 0.0564984818476863 1.0 0.4478211747302373 8 P13473,P10619 2 +Erk1 and erk2 cascade 0.5195776863027772 1.9066168199566789 0.0565702253833921 1.0 0.4478211747302373 46 Q04721,P06756,P14174,P29317,Q15375,P00533,O14786,P05067,Q13641 9 +Synaptic transmission gabaergic 0.8071780295234785 1.9064201003430723 0.0565957229180111 1.0 0.4478211747302373 6 P51790,Q9BQT9 2 +Olfactory lobe development 0.8810184122640399 1.9037223771990817 0.0569463505029026 1.0 0.4500641993755348 4 O94813 1 +Regulation of phospholipase a2 activity 0.8304160698214714 1.9018739484789375 0.0571876357455105 1.0 0.4501770566227532 5 Q07954,P50897 2 +Semi lunar valve development 0.805950587520762 1.9013400566373588 0.0572574855549055 1.0 0.4501770566227532 6 O94813,Q9Y6N7 2 +Signaling receptor ligand precursor processing 0.7703422689638667 1.9013111564493976 0.0572612686300733 1.0 0.4501770566227532 7 P42892,P07711,P16870 3 +Positive regulation of gliogenesis 0.7220980157032034 1.9010422178854585 0.0572964830347968 1.0 0.4501770566227532 10 P98164 1 +Neuron apoptotic process 0.5113309293046224 1.8996254900972156 0.0574822846657572 1.0 0.4511080466392329 51 Q99538,Q04446,P50897,Q9NR28,O95831,Q92542,P31751,P04062,Q15375,O14786,P05067 11 +Autophagy of mitochondrion 0.5243299719467054 1.8952002076073589 0.0580658826743871 1.0 0.4546233010324099 40 P21796,Q7Z3C6,P53365,Q13501,P04062,Q8TDY2,Q9NQ11 7 +Regulation of leukocyte mediated immunity 0.5262158942681152 1.894480337662352 0.0581612818023582 1.0 0.4548388688907875 37 P04439,Q9NRA0,P01889,Q6PIJ6,Q9BY67,P02786,O15400,P51809,P11279,Q92692 10 +Low density lipoprotein particle clearance 0.6879517411664388 1.8906331822409397 0.0586733275630038 1.0 0.4572426061944785 12 P01130,Q9H4M9,P61978,P38571,Q8WTV0,P35610 6 +Regulation of neutrophil migration 0.7512724959021164 1.889262414202178 0.0588566751956347 1.0 0.4581387191186342 8 Q07021,O94813,Q00013 3 +Regulation of protein folding 0.8268933114641159 1.8875905309905745 0.059080942265246 1.0 0.458818626954437 5 Q9H2J4,Q9UL15 2 +Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules 0.8263440860215142 1.885361924549377 0.0593809909226248 1.0 0.4590759432447032 5 Q9BY67,Q9P273,Q13740,P78310 4 +Cellular response to exogenous dsrna 0.7665068983126672 1.884813325177245 0.0594550452839997 1.0 0.4590759432447032 7 Q5KU26,O75955,P41440 3 +Neuroinflammatory response 0.8261841998810899 1.8847130639297187 0.0594685876332017 1.0 0.4590759432447032 5 P01130,P53634 2 +Humoral immune response 0.6734067649163481 1.8837886848936451 0.059593564700521 1.0 0.4590759432447032 13 Q04721,Q9UQ84,P04439 3 +Regulation of lymphocyte mediated immunity 0.5713250638921286 1.8813971202138675 0.059917918321612 1.0 0.4597981376997265 25 P04439,P01889,P02786,O15400,P11279,Q92692 6 +Alpha beta t cell activation 0.616882068990209 1.880282404547894 0.0600696000322129 1.0 0.4597981376997265 18 Q9NQZ7,P07711,P04439,Q04656,Q96J02 5 +Syncytium formation 0.7323808653964673 1.877376990258263 0.0604664428562342 1.0 0.4597981376997265 9 Q9H4M9,O75955,Q6YHK3,P41440,P05556 5 +Regulation of cellular response to transforming growth factor beta stimulus 0.6293339896238983 1.8758274928244087 0.0606789715129176 1.0 0.4597981376997265 16 Q9NYA4,Q92896,O00560,Q6YHK3 4 +Cell adhesion molecule production 0.8737931777102805 1.8751418317233255 0.0607732139727519 1.0 0.4597981376997265 4 Q5KU26,P41440 2 +Hindbrain morphogenesis 0.6716451900082321 1.8748561871350344 0.060812510900952 1.0 0.4597981376997265 13 Q7Z4L5,Q15058,Q04656,P04062,P18887 5 +Response to nerve growth factor 0.6579153063756437 1.874358577964455 0.0608810186747421 1.0 0.4597981376997265 14 Q9H4M9,Q99523,P05067,Q9ULH0,Q05086 5 +Cd4 positive alpha beta t cell differentiation 0.7478824529463478 1.8743101772320077 0.0608876856009472 1.0 0.4597981376997265 8 Q9NQZ7,P07711,Q04656 3 +Extracellular vesicle biogenesis 0.6999619163697632 1.8709972620094704 0.0613454605242957 1.0 0.4597981376997265 11 Q92783,Q9Y3E7,O00560,Q9NQ11,O14964 5 +Morphogenesis of an epithelium 0.4550490428615943 1.87011598404223 0.0614677132932155 1.0 0.4597981376997265 78 P22694,Q14344,Q14118,P00533,Q13308,Q8TAA9,Q14517,P11233,O15031,Q5SZK8,P67870,P17612,P98164,O14641,P62993,P29317,Q04656,O14786,Q04721,P17252,O94813,O00592,Q15375 23 +Regulation of synapse structure or activity 0.5217702767546275 1.8696158928246067 0.0615371766849763 1.0 0.4597981376997265 39 P50897,Q15375,Q14118,Q9Y4F1,Q9BQT9,P05067,P46934,Q13641 8 +Detection of biotic stimulus 0.7979959919819719 1.868355462589952 0.0617125406261713 1.0 0.4597981376997265 6 P04439,P01889 2 +Amino acid transmembrane transport 0.6146995831831613 1.8676978705687937 0.0618041956317538 1.0 0.4597981376997265 18 Q9H2J7,Q96QD8,Q9Y619,P08195,P30825,P05556 6 +Lipoprotein catabolic process 0.7624736423464404 1.867433194105242 0.061841117954982 1.0 0.4597981376997265 7 P50897 1 +Interferon gamma production 0.7463205992588583 1.8674132807590245 0.0618438966017766 1.0 0.4597981376997265 8 Q07021,P04439,Q08722 3 +Positive regulation of natural killer cell mediated immunity 0.8717475518151842 1.867038091927584 0.061896268608713 1.0 0.4597981376997265 4 P11279,Q92692 2 +Positive regulation of natural killer cell mediated cytotoxicity 0.8717475518151842 1.867038091927584 0.061896268608713 1.0 0.4597981376997265 4 P11279,Q92692 2 +Lipoprotein localization 0.7976645672998116 1.866978828894571 0.0619045443961425 1.0 0.4597981376997265 6 Q07954,A6NIH7 2 +Protein lipid complex subunit organization 0.7623559493195665 1.866925553670592 0.0619119847974574 1.0 0.4597981376997265 7 Q8WTV0,P35610,P17612,P22694 4 +Positive regulation of immune effector process 0.5170028116091216 1.866832854602151 0.0619249328849098 1.0 0.4597981376997265 44 P14174,P04439,Q9NRA0,P01889,P02786,O15400,Q06481,P51809,P11279,Q92692 10 +Positive regulation of wound healing 0.7297475578377292 1.8654642353743187 0.0621163607957055 1.0 0.4597981376997265 9 P05556,Q16625,Q9Y6X5 3 +Positive regulation of neural precursor cell proliferation 0.7971370022067447 1.8647871047696385 0.0622112515223056 1.0 0.4597981376997265 6 P55209,P98164 2 +Pathway restricted smad protein phosphorylation 0.8212737162440495 1.8647661077669608 0.0622141958851725 1.0 0.4597981376997265 5 Q9H3E2,O00560,Q07954 3 +Chemokine production 0.6986442541181006 1.86468379016508 0.0622257402109298 1.0 0.4597981376997265 11 P05067,P29317,P14174 3 +Regulation of er to golgi vesicle mediated transport 0.7962318207051863 1.8610255050343152 0.0627405750142044 1.0 0.4625823253522536 6 Q92673 1 +Negative regulation of mrna catabolic process 0.5639365388702492 1.8571250415501035 0.0632933662596579 1.0 0.4651229612634077 26 P35637,Q14011,Q9NRA8,Q13151,Q92804,O60506,Q06787,P67809,P07910,Q14103,Q99729,P98175 12 +Retinal ganglion cell axon guidance 0.8192675058009264 1.8566061700846035 0.063367205472534 1.0 0.4651555433482182 5 Q15375,O94813 2 +Receptor internalization 0.5636388188495044 1.855145496415578 0.0635754523602201 1.0 0.465481489264445 26 P02786,O75955,O00560,P41440,Q07954,P46934,P05556 7 +Sterol homeostasis 0.6676419602559056 1.8545226422986163 0.0636644238788894 1.0 0.465481489264445 13 P01130,Q9H4M9,P61916,P34913,Q8WTV0,O15118 6 +Phosphatidylcholine metabolic process 0.6539038592104693 1.8533770590558447 0.0638283331295173 1.0 0.465481489264445 14 Q8NCC3,P01130,Q8WTV0 3 +Fucose metabolic process 0.8679332122802397 1.8519137178105711 0.0640382137763879 1.0 0.4658939061976248 4 P04066,Q9BTY2 2 +Circulatory system process 0.4685656788274462 1.851529380185588 0.0640934320373336 1.0 0.4658939061976248 88 P42785,Q9HB40,Q16625,Q96QD8,Q14344,P55011,P07947,Q9UIQ6,P33527,P10253,P04899,P17612,P11166,P0DP25,P29992,P98164,O75787,O00429,O75844,P02786,P41440,P42892,Q14126,Q99808,P17252,O94813,P30825,P78310,Q07954,P05026 30 +Regulation of neutrophil chemotaxis 0.7576754616515267 1.8467155720288944 0.0647883736168761 1.0 0.4695006433950378 7 Q07021,O94813,Q00013 3 +Regulation of exosomal secretion 0.7103209575862429 1.8462591318805328 0.0648545887132876 1.0 0.4695006433950378 10 Q92783,Q9Y3E7,O00560,Q9NQ11,O14964 5 +Positive regulation of macroautophagy 0.5809005635023926 1.845515677375113 0.0649625600857064 1.0 0.4695006433950378 22 P27544,O15269,P21796,Q13137 4 +Leukocyte cell cell adhesion 0.5153046372452947 1.8449669243720297 0.0650423501816099 1.0 0.4695006433950378 43 P04439,Q9HCL2,Q08722,P10644,Q96J02,P02786,P30825,P07947,Q14254,Q9Y624,P05556 11 +Regulation of ras protein signal transduction 0.5191857253582648 1.8447082460061064 0.0650799907063548 1.0 0.4695006433950378 38 Q04721,Q13501,O75955,O95819,O14786,P41440,Q9Y624,Q9Y6N7 8 +Negative regulation of cell killing 0.8659917877783432 1.8442088281431248 0.0651527122859265 1.0 0.4695198685379353 4 P04439 1 +Positive regulation of phagocytosis 0.6654459620953375 1.8433484143153616 0.0652781566552411 1.0 0.469918588510662 13 P17301,Q08431,Q06481,Q08722 4 +Cytochrome complex assembly 0.7240634077294354 1.8396966181913823 0.0658127903348679 1.0 0.4712364538720995 9 Q6DKK2,Q9Y2R0,Q69YU5,P53701 4 +Positive regulation of response to wounding 0.6773618420885659 1.8383371962956812 0.0660127332796733 1.0 0.4712399478873487 12 Q04656,Q16625,P05556,Q9Y6X5 4 +Positive regulation of synapse assembly 0.8629170254206256 1.8319966910898304 0.0669519135930318 1.0 0.4732062934705126 4 Q9BQT9 1 +Regulation of steroid metabolic process 0.6014724750604644 1.8314390929190971 0.067035030824514 1.0 0.4732062934705126 19 P01130,P34913,Q9H2C2,Q13510 4 +Acute inflammatory response 0.8129123320464697 1.8307178389822876 0.0671426690457113 1.0 0.4732062934705126 5 P02786,Q9BQE5,P42785 3 +Sphingomyelin metabolic process 0.7380234440186865 1.8306888472809395 0.0671469986706143 1.0 0.4732062934705126 8 Q92485,Q92484 2 +Epithelial tube morphogenesis 0.5059995170462998 1.8287881873832932 0.0674313452656909 1.0 0.4744805795377509 49 Q04721,O14641,P11233,P17252,O15031,P29317,O94813,P22694,O00592,Q14344,Q14118,Q15375,Q13308,P67870,P17612,O14786,P98164 17 +Regulation of defense response 0.4969850811336963 1.8276706972147 0.0675989884555929 1.0 0.4748935226723104 109 Q92485,P01889,P04062,Q8NCG7,P05067,P17301,O43405,P53634,Q07021,Q96J02,Q06481,P51809,P01130,P04439,Q9BY67,Q08722,O75844,O43657,P11279,Q92692 20 +Ovulation cycle process 0.7879197781511744 1.8264191294456669 0.0677871525645321 1.0 0.4757167502486853 6 P19021,O94813 2 +Negative regulation of defense response to virus 0.7367966845298013 1.825246877155421 0.0679637826997463 1.0 0.4759595315085684 8 Q07021,O43657 2 +Cellular carbohydrate catabolic process 0.6001046643282515 1.8233553723373113 0.0682495848213486 1.0 0.4774621267982034 19 Q14108,P43304,P08236,P10253 4 +Positive regulation of locomotion 0.4862149130048985 1.820213858731924 0.0687264434213597 1.0 0.4789912519431934 102 P00533,Q8WTV0,P05067,Q99538,P17301,P06756,Q07021,P04899,Q13641,P29317,Q08722,Q04656,Q13685,O95819,O14786,P05556,P31751,O94813,O00592,P43121,O00560,Q13049 22 +Presynapse organization 0.7514026014972147 1.8195634556748956 0.0688255111341831 1.0 0.4789912519431934 7 P05067,Q9BQT9,O00560 3 +Genitalia development 0.7860795583865228 1.8187419210893396 0.0689508128427425 1.0 0.47936550588388 6 P98164 1 +Neuron projection extension involved in neuron projection guidance 0.8594463853802636 1.8181985433717336 0.0690337925737814 1.0 0.4794450547455781 4 P51805,O94813,O14786 3 +Negative regulation of lymphocyte mediated immunity 0.8590553383770544 1.8166429644237565 0.0692718002319525 1.0 0.4797326484109384 4 P04439 1 +Diacylglycerol metabolic process 0.8589299864338851 1.8161442778690484 0.0693482430916145 1.0 0.4797326484109384 4 Q8NCC3 1 +Dendritic cell differentiation 0.8588423198543638 1.815795503585771 0.0694017472991948 1.0 0.4797326484109384 4 P01889 1 +Regulation of receptor recycling 0.7501849859673271 1.814284245730643 0.0696339757507351 1.0 0.4801305611948838 7 P01130 1 +Collateral sprouting 0.8581307176274064 1.8129641153829752 0.0698373561753953 1.0 0.4805441078927099 4 P05067 1 +Regulation of blood pressure 0.5833872798410671 1.8117454267739337 0.0700255409887262 1.0 0.480642762101059 21 P42892,Q9UIQ6,Q9HB40 3 +Cartilage development 0.6319744000400556 1.810683169749543 0.070189909566104 1.0 0.480642762101059 15 O75844,Q92896,Q15043,Q9NX62 4 +Endothelial cell migration 0.5100050591971195 1.8105516961835209 0.0702102751562125 1.0 0.480642762101059 44 Q99538,P42785,P29317,O94813,Q13685,O14786,Q8WTV0,Q9Y6N7,P05556 9 +Angiogenesis involved in wound healing 0.8572964256920036 1.8096437951454143 0.0703510437248793 1.0 0.4811149949430012 4 P43121,Q14118,P42785 3 +Regulation of rho protein signal transduction 0.6108201848975612 1.8072880041433332 0.0707173854413394 1.0 0.4831273366237073 17 O75955,P41440,O14786,Q9Y624,Q9Y6N7 5 +Negative regulation of response to biotic stimulus 0.5742655991558874 1.8038108819573688 0.0712609593385857 1.0 0.4834501707373034 22 P04439,P01889,Q07021,Q96J02,O43657 5 +Negative regulation of axon extension 0.8061966151182135 1.8032961197691433 0.0713417217038485 1.0 0.4834501707373034 5 P51805,O14786 2 +Granulocyte chemotaxis 0.6160432522265876 1.801658235206862 0.0715991928598198 1.0 0.4847048389358714 16 P35613,Q07021,O94813,P78310 4 +Negative regulation of neuron apoptotic process 0.5516894189318216 1.8005407323148184 0.0717752979646553 1.0 0.4848855198321835 27 Q99538,P04062,P50897,O14786 4 +Ion homeostasis 0.5205070619416854 1.80016726966229 0.0718342302690657 1.0 0.4848855198321835 128 Q93050,P30519,Q15904,Q9Y487,P05067,O75503,P06756,P50897,P51790,Q9H7F0,P07686,P04899,Q13772,Q9NQ11,P02792,Q9NUM4,Q8NE01,O75787,Q04656,P02786,Q6P4Q7,Q15043,Q7L0J3,Q92859,Q8N511,Q9BXP2,Q92544,Q9HD20,Q92581,P05026,Q05086,Q9Y6M7 32 +Regulation of mast cell activation 0.7816195967114423 1.8001121553594892 0.0718429306465768 1.0 0.4848855198321835 6 P51809,Q9NRA0,Q92692 3 +Heart valve morphogenesis 0.781347550463709 1.7989747270114544 0.0720226786030395 1.0 0.484958992702544 6 O94813,Q9Y6N7 2 +Maternal process involved in female pregnancy 0.656299770796411 1.7966557555414118 0.0723902870471375 1.0 0.486619562477348 13 Q9BQE5,P19021,P07858 3 +Smad protein signal transduction 0.699556400955508 1.7958939709010873 0.0725113815069404 1.0 0.4868758790680353 10 Q9UIQ6 1 +Striated muscle cell differentiation 0.5059312868034302 1.7955022800262683 0.0725737098163186 1.0 0.4868758790680353 46 Q9H4M9,Q99523,Q8IV08,O75844,P10644,O75955,P67809,P78310,P41440,P05556,Q13049 11 +Innervation 0.8535339962375599 1.7946598988037112 0.0727079033882787 1.0 0.4869147612336141 4 P42892,O94898,O14786 3 +Cellular response to dsrna 0.7139297614692932 1.7935792726614337 0.0728803473156398 1.0 0.4869147612336141 9 Q5KU26,O75955,P41440 3 +Negative regulation of smooth muscle cell migration 0.7798949353418301 1.7928992740069645 0.0729890314650365 1.0 0.4869147612336141 6 O94813 1 +Retina homeostasis 0.803574364391379 1.7925711292432305 0.0730415262467949 1.0 0.4869147612336141 5 P51790 1 +Protein localization to synapse 0.6423064161478187 1.7924332766932958 0.073063588346933 1.0 0.4869147612336141 14 P33176,Q9UQB8,Q14168,Q14118,Q9BQT9 5 +Regulation of endothelial cell migration 0.518608416587994 1.7897875140963628 0.0734880771744708 1.0 0.4870926258233602 34 Q99538,P42785,P29317,O94813,Q13685,O14786,Q8WTV0 7 +Plasma membrane organization 0.5284939740887481 1.789374104607018 0.0735545868562557 1.0 0.4870926258233602 32 Q7Z3C6,Q9UKS6,P31751,Q4KMQ2,O75955,Q9H2C2,Q9Y3E7,Q16739,P41440,Q96CP7 10 +Cd4 positive alpha beta t cell activation 0.6981544827237268 1.789314359314527 0.0735642028012582 1.0 0.4870926258233602 10 Q9NQZ7,P07711,Q04656 3 +Jnk cascade 0.5499492090140117 1.7887312352993 0.0736581100215529 1.0 0.4870926258233602 27 Q96J02,P00533,O95819,O00560,P05067,Q8TDY2 6 +Negative regulation of leukocyte mediated immunity 0.7787428356371926 1.788078250464424 0.0737633840588614 1.0 0.4870926258233602 6 P04439 1 +Regulation of glucose transmembrane transport 0.6278063308282508 1.7880441987988156 0.0737688772322755 1.0 0.4870926258233602 15 P07947,Q16625,P31751,Q06481 4 +Adenylate cyclase activating g protein coupled receptor signaling pathway 0.7121202564267239 1.7853204239648155 0.07420935786944 1.0 0.4875050376291294 9 Q14344,P04899,O60266,P48960 4 +Metal ion homeostasis 0.4725918452246138 1.785275757921165 0.0742165990016288 1.0 0.4875050376291294 95 P30519,Q15904,Q14344,Q9Y487,P55011,P05067,P06756,Q9H7F0,P07686,Q9Y666,P04899,P17612,Q13772,P0DP25,Q9NQ11,P02792,Q9NWR8,Q8NE01,Q04656,P98194,P02786,Q6P4Q7,Q15043,Q7L0J3,P17252,Q92859,Q8N511,Q9BXP2,Q9HD20,Q8NEN9,P05026 31 +Synaptic transmission glutamatergic 0.7277587481883412 1.7850585484038115 0.0742518206243116 1.0 0.4875050376291294 8 P51790 1 +Monocyte chemotaxis 0.7432029870110991 1.7839579687549605 0.0744304952054133 1.0 0.4880950869536988 7 Q99538,O94813 2 +Negative regulation of smoothened signaling pathway 0.7115143229676115 1.78255324260935 0.074659056905834 1.0 0.488681446083851 9 P22413,O60291,P22694,P17612,Q6PHR2 5 +Regulation of leukocyte degranulation 0.7271873676071858 1.7825122112609844 0.0746657416875355 1.0 0.488681446083851 8 P11279,P51809,Q9NRA0 3 +Positive regulation of mapk cascade 0.4774256387655793 1.779059437313178 0.0752300179054425 1.0 0.4898682864114227 61 Q04721,Q9Y2Q5,P14174,O14641,P17252,Q86VI3,P19022,O43164,P00533,P04899,O00560,O14786,P05067,Q8TDY2,Q13641,Q9Y6N7 16 +Cell migration involved in sprouting angiogenesis 0.7104018586641803 1.77747073185856 0.0754908222017072 1.0 0.4901427862163691 9 O94813,Q9Y6N7,O14786 3 +Response to catecholamine 0.5990280069434557 1.7767915602899576 0.075602540991404 1.0 0.4901427862163691 18 P08754,P09471,Q92542,P17612,P05067,P29992 6 +Pyrimidine nucleotide catabolic process 0.8490255363960721 1.776683319690515 0.0756203582434684 1.0 0.4901427862163691 4 Q9H773,P13051 2 +Negative regulation of rna catabolic process 0.5166888069331037 1.7753278759066748 0.0758437652090464 1.0 0.4904986225306189 34 P35637,Q9NRA8,Q13151,Q14103,Q96HR8,Q9GZT3,Q08J23,Q92804,O60506,Q06787,P67809,P07910,Q14011,Q99729,P98175 15 +Positive regulation of leukocyte mediated immunity 0.5476337786135907 1.7729934102081193 0.0762297988283715 1.0 0.4904986225306189 27 P04439,P01889,P02786,O15400,P11279,Q92692 6 +Alcohol metabolic process 0.4757464115586945 1.772410829274904 0.0763263854647533 1.0 0.4904986225306189 98 Q9BQE5,P43304,Q9NX62,Q9NWW5,P04062,Q8WTV0,P05067,P98155,Q9BXW6,Q9NRA0,P61916,O75845,P56937,Q13510,O15269,Q16850,P01130,Q15392,Q15800,Q9H2C2,P48735,P34913,O15118 23 +Reticulophagy 0.7404024253185613 1.7717678731641804 0.0764330975925835 1.0 0.4904986225306189 7 Q9Y6I9 1 +Response to ischemia 0.6792093013341359 1.7710433074924057 0.0765535003233404 1.0 0.4904986225306189 11 O95831,Q13501 2 +Regulation of glucose import 0.6625917409354033 1.7648799219536095 0.0775839487810847 1.0 0.4962227054161406 12 Q16625,Q06481 2 +Modified amino acid transport 0.723163892724527 1.764562970273023 0.0776372434923313 1.0 0.4962227054161406 8 Q9H2D1,Q96QD8,P98164 3 +Positive regulation of protein localization to cell periphery 0.5676099841310478 1.7617748886289033 0.07810733907859 1.0 0.4962227054161406 22 Q13501,P33176,P29317,P98194,P00533,P63096,Q07954,P05556 8 +Regulation of b cell proliferation 0.7380323555027606 1.7614401206673795 0.0781639394641173 1.0 0.4962227054161406 7 P02786,Q9NPF0 2 +Negative regulation of immune effector process 0.7067713177218526 1.7608650314714775 0.0782612497435395 1.0 0.4962227054161406 9 P04439,P01889 2 +Diet induced thermogenesis 0.9863013698630136 1.7608645874052018 0.0782613249216443 1.0 0.4962227054161406 2 Q92673 1 +Regulation of cell development 0.4802325171308638 1.7588110675697444 0.0786096043173856 1.0 0.4972996808265024 102 Q9P265,P55209,Q14118,P51805,Q9Y624,Q16706,O15031,Q07021,Q92673,Q06481,P98164,P01130,Q96G23,O14786,Q04721,O94813,Q15375,Q13049,Q9Y6N7 19 +Negative regulation of cell growth 0.5241471694045631 1.757605863449811 0.0788145949934606 1.0 0.4972996808265024 32 Q8N0X7,Q9P265,P50897,Q9NRA0,P22413,O94813,Q15375,O14786,P51805 9 +Peptidyl proline hydroxylation 0.7213379473744859 1.7564063946432216 0.0790190417495808 1.0 0.4972996808265024 8 O75718,Q32P28 2 +Photoreceptor cell maintenance 0.8437128827610049 1.755470556161193 0.079178852716232 1.0 0.4972996808265024 4 P51790 1 +Regulation of calcium ion import 0.8432654024944795 1.7536823838106668 0.0794849457151367 1.0 0.4972996808265024 4 P21796,Q9NRA0 2 +Positive regulation of nervous system process 0.7704572856482007 1.7533435854035355 0.0795430482925734 1.0 0.4972996808265024 6 P04062,Q14118 2 +Iron ion transmembrane transport 0.7938113527561177 1.752554434868907 0.0796785183556751 1.0 0.4972996808265024 5 Q15043,Q04656 2 +Glial cell proliferation 0.7693897277195446 1.7488601614126735 0.0803151944148403 1.0 0.4972996808265024 6 P04062 1 +Phenol containing compound metabolic process 0.6745781256256437 1.7485875167616598 0.0803623456603064 1.0 0.4972996808265024 11 P21964,P07858 2 +Reactive nitrogen species metabolic process 0.5875053650568156 1.7485409628283397 0.0803703989582826 1.0 0.4972996808265024 19 O43169,P06280 2 +Leukocyte degranulation 0.6339067241757216 1.7480315035944325 0.080458572428844 1.0 0.4972996808265024 14 P11279,P51809,Q9NRA0,O00161 4 +Regulation of cell adhesion 0.5000211295761526 1.7445434679655616 0.0810643686704182 1.0 0.4972996808265024 117 Q9P273,P23458,O75955,Q14118,P07947,P51805,Q9Y624,P17301,P06756,O15031,Q07021,P10644,Q96J02,P04439,P29317,P14543,Q08722,P02786,O14936,O95819,O14786,Q14254,O00592,Q15375,P30825,P41440,Q9HCL2 27 +Apoptotic dna fragmentation 0.7916195649780255 1.743552386609499 0.0812371719388029 1.0 0.4972996808265024 5 O00115 1 +Mast cell activation 0.6884107668757456 1.7434562321829246 0.081253953160731 1.0 0.4972996808265024 10 Q92692,P51809,Q9NRA0,O00161 4 +Myeloid cell development 0.5996619896610643 1.7434195803562318 0.0812603505120583 1.0 0.4972996808265024 17 Q04721,P05067,Q15904 3 +Mammary gland development 0.5432804040373173 1.743327434299357 0.081276435846425 1.0 0.4972996808265024 27 P17301,P29317,P31751,Q04656,P19021,Q9Y6N7 6 +Potassium ion homeostasis 0.7680629431073739 1.7432855404668888 0.0812837498332081 1.0 0.4972996808265024 6 Q9BXP2,P05026,P55011 3 +Inflammatory cell apoptotic process 0.7678697259255376 1.7424734861673097 0.081425626964962 1.0 0.4974608495161126 6 P07711 1 +Cerebellar cortex formation 0.718118479490235 1.7420085756145405 0.0815069436959241 1.0 0.4975041317396025 8 P04062,Q04656 2 +Regulation of hormone levels 0.4492812557886584 1.7411491304947446 0.0816574413099922 1.0 0.4975208566816901 70 P42892,P07711,O95470,P07858,Q9HB40,P56937,O75787,O75844,P51809,P16870,Q15043,Q9UBM7 12 +Regulation of lysosome organization 0.98146655922643 1.7411450685048149 0.0816581531408324 1.0 0.4975208566816901 2 Q14108 1 +Positive regulation of chemokine production 0.7177678264790219 1.740439163490127 0.0817819337579985 1.0 0.4978224523579532 8 P05067,P14174,Q13049 3 +Cyclic nucleotide metabolic process 0.7904415454977216 1.738711325030023 0.0820855529764581 1.0 0.4987646201706459 5 O60266 1 +Neural tube patterning 0.7901363944150166 1.737456998918296 0.0823065378486089 1.0 0.4992021870238709 5 O75787,P17612,P22694 3 +Response to dsrna 0.6042520950337616 1.735328953148155 0.0826825562577695 1.0 0.5010293779742961 16 Q5KU26,P08195,P41440 3 +Cell cell adhesion mediated by cadherin 0.7315208426099674 1.733012068195966 0.0830935238193162 1.0 0.5021920021299449 7 O60716,O75955,Q6IQ23,P41440 4 +Cell matrix adhesion 0.4993527330358911 1.7324327295633466 0.0831965447712006 1.0 0.5021920021299449 45 P17301,P06756,Q9UM22,P14543,Q14118,O14936,O95819,O14786 8 +Mitochondrial respiratory chain complex assembly 0.5057719484031382 1.73158558049306 0.0833473753975941 1.0 0.5021920021299449 35 Q69YU5,O95831,Q6DKK2,O43676,P51970,O96000,Q9Y2R0,Q9Y6M9 8 +Regulation of innate immune response 0.4928302581858557 1.7301444254982234 0.0836044746333222 1.0 0.5021920021299449 50 P04439,O43405,P01889,Q06481,P11279,Q92692 6 +Cellular response to mechanical stimulus 0.5973377177854793 1.7300579384526071 0.083619924158022 1.0 0.5021920021299449 17 P17301,Q14118,Q96QD8,Q9Y624 4 +Granulocyte migration 0.5843635081980931 1.7297859433972074 0.083668526784884 1.0 0.5021920021299449 19 P35613,Q07021,O94813,P78310 4 +Neurotrophin signaling pathway 0.7307332877479735 1.729568458510374 0.0837074054794799 1.0 0.5021920021299449 7 Q99523 1 +Positive regulation of monocyte chemotaxis 0.8371543872753464 1.7292402715530326 0.0837661015254904 1.0 0.5021920021299449 4 Q99538 1 +Phospholipid dephosphorylation 0.7300926809487004 1.726766547534946 0.0842095986223905 1.0 0.5043545397383925 7 Q9NYA4,P34913 2 +Exocytosis 0.4594183089010092 1.7253277390541917 0.0844684256661112 1.0 0.5054530257270335 90 Q9H270,Q9Y3E7,Q9UEU0,P11233,Q9NRA0,Q8WU76,P04899,O95721,P51809,P0DP25,Q9NQ11,P56545,Q4J6C6,O14936,Q5SQN1,P11279,Q7L0J3,P51151,O00161,Q06787,Q92783,O00560,Q15833,O43760,O14964 25 +Ventricular septum development 0.6836341315757888 1.720894293038799 0.0852700073778904 1.0 0.5082487161552321 10 O94813,P98164 2 +Macroautophagy 0.5058227718908634 1.7199982279549717 0.0854327636947873 1.0 0.5082487161552321 123 Q93050,Q7Z3C6,Q13501,P27544,P51149,P13473,P04062,Q9Y3E7,Q9Y487,Q9Y2S7,Q9UEU0,P16615,P53365,Q9Y6I9,O15269,P60520,P51809,P17612,O95721,Q96KQ7,Q9NQ11,Q9UK41,Q9H9H4,P08754,Q86Y82,Q5MNZ6,Q13137,P46934,Q9H0U4,P21796,P17252,Q9BRG1,Q92783,Q6PHR2,Q8TDY2,O15118,Q8NHS3,O14964 38 +Membrane raft assembly 0.7620093780254834 1.7178156998594174 0.0858302369386365 1.0 0.5082487161552321 6 O75955,P41440 2 +Regulation of small gtpase mediated signal transduction 0.489897200738905 1.717750919312257 0.0858420573079761 1.0 0.5082487161552321 51 Q04721,P06756,Q13501,O94813,O75955,O95819,O14786,P41440,Q9Y624,Q9Y6N7 10 +Pyrimidine deoxyribonucleotide metabolic process 0.7279411957939713 1.7173508225752971 0.0859150912668833 1.0 0.5082487161552321 7 Q9H773 1 +Regulation of nitric oxide synthase activity 0.7125041923101737 1.7168514234015964 0.086006322404275 1.0 0.5082487161552321 8 Q8WTV0,P00533,P06280,P0DP25 4 +Heart formation 0.7846766799549689 1.714993422607704 0.0863464328457759 1.0 0.5082487161552321 5 P98164 1 +Gdp metabolic process 0.8331093791991294 1.7130394770445792 0.0867052771973884 1.0 0.5082487161552321 4 Q14168,Q00013,O14936 3 +Phosphatidylethanolamine metabolic process 0.8328164153402828 1.7118654491480294 0.0869214672299389 1.0 0.5082487161552321 4 Q8NCC3 1 +Walking behavior 0.8328001468769839 1.7118002520323286 0.0869334856205044 1.0 0.5082487161552321 4 O15118 1 +Inorganic ion import across plasma membrane 0.6397468657550396 1.711530744107273 0.0869831807564982 1.0 0.5082487161552321 13 Q9BXP2,Q9Y666,P55011,P05026,Q92581,Q15043 6 +Positive regulation of exosomal secretion 0.6955694310684919 1.709448597797977 0.0873678854684834 1.0 0.5090952426142892 9 Q92783,Q9NQ11,O00560,O14964 4 +Natural killer cell activation 0.6811421682643184 1.7091028242228092 0.0874319045432776 1.0 0.5090952426142892 10 P46379,P11279,P51809,Q96L92 4 +Macrophage differentiation 0.7099139921049056 1.7052239594748413 0.0881526631107514 1.0 0.5124016896515664 8 P05067 1 +Regulation of t cell activation 0.5018958079124922 1.7037822296093108 0.0884217790747983 1.0 0.5128527745101039 36 P04439,Q9HCL2,Q08722,P10644,Q96J02,P02786,P30825,P07947,Q14254 9 +Bone resorption 0.7095630696167186 1.7036476485997485 0.0884469339738589 1.0 0.5128527745101039 8 O14773 1 +Regulation of lipid metabolic process 0.4513881899552376 1.7034428977978997 0.0884852155615216 1.0 0.5128527745101039 68 P01130,Q96G23,Q2T9J0,Q9NRA0,Q9NYA4,P61916,P31751,Q13510,Q8NBJ4,O75844,Q92673,Q9H2C2,P07602,Q06481,P34913,Q8WTV0,Q9H6K4 17 +Regulation of nik nf kappab signaling 0.5863579420485104 1.7026060786464792 0.0886418117554124 1.0 0.5128527745101039 18 P05067,O43657 2 +Late endosome to vacuole transport 0.6937797847646091 1.7012092224534825 0.0889037066847138 1.0 0.5128527745101039 9 Q9UK41,Q9BRG1,Q92783,Q9Y3E7,Q9H3S7 5 +Sensory perception 0.4964144996664509 1.700220901609919 0.0890893821331546 1.0 0.5128527745101039 44 P17301,P50897,O43405,P07686,O94898,O60266,Q6P4Q7,Q9H6K4,Q14108,P98164 10 +Ovulation cycle 0.6789146662057548 1.6985506584470194 0.0894038800188783 1.0 0.5128527745101039 10 P19021,O94813 2 +Negative regulation of blood pressure 0.8294027009701181 1.6981787220345932 0.0894740352414922 1.0 0.5128527745101039 4 Q9HB40 1 +Regulation of neurotransmitter uptake 0.8287802635207849 1.6956818714585349 0.0899461435217914 1.0 0.5128527745101039 4 O75955,P41440 2 +Response to testosterone 0.6363902342002885 1.69417278351238 0.0902324549821467 1.0 0.5128527745101039 13 Q13772 1 +Glycosyl compound metabolic process 0.5104782915823318 1.6914874885228133 0.0907437353679174 1.0 0.5128527745101039 33 Q9BTY2,P06280,Q9Y6X5,P08236,P04066 5 +Regulation of extracellular matrix organization 0.7554361438723202 1.6900950477508896 0.0910097721768319 1.0 0.5128527745101039 6 Q07954 1 +Immune response regulating cell surface receptor signaling pathway 0.5102579910835476 1.6898370817392996 0.0910591274119032 1.0 0.5128527745101039 33 P04439,Q08722,Q07666,Q06481,Q7KYR7,P07947,Q5ZPR3,Q92692 8 +Positive regulation of jnk cascade 0.6766078753059628 1.687610931691795 0.0914859393886011 1.0 0.5136919085430199 10 P05067,Q8TDY2,O00560 3 +Metencephalon development 0.4997390128740003 1.687011800402799 0.0916010829380915 1.0 0.5136919085430199 36 P54802,Q7Z4L5,Q15058,Q92542,Q04656,Q5KU26,P04062,O15228,Q14103,P18887,O75882 11 +Forebrain cell migration 0.6469918616536334 1.6866510226458038 0.0916704748757761 1.0 0.5136919085430199 12 P00533,O94813,Q9Y6N7 3 +Diacylglycerol biosynthetic process 0.9672307279076026 1.6830178408010017 0.0923716377545318 1.0 0.5140728203133679 2 Q8NCC3 1 +Response to metal ion 0.4434534182621273 1.6817788834614882 0.0926117249302695 1.0 0.5140728203133679 70 Q99538,P35613,Q92542,Q04656,Q14168,P02786,P00533,O15118,O60888,Q9NQ11,P05067,P19021 12 +Dorsal ventral pattern formation 0.7195006346948505 1.6803310493064476 0.0928929231810631 1.0 0.5140728203133679 7 P17612,P17252,Q7Z4L5,P22694 4 +Axon midline choice point recognition 0.9664249261348412 1.6797250985386043 0.0930108141555383 1.0 0.5140728203133679 2 P05067 1 +Axon choice point recognition 0.9664249261348412 1.6797250985386043 0.0930108141555383 1.0 0.5140728203133679 2 P05067 1 +Olfactory bulb interneuron development 0.9664249261348372 1.6797250985385894 0.0930108141555412 1.0 0.5140728203133679 2 O94813 1 +Negative regulation of chemokine mediated signaling pathway 0.9664249261348372 1.6797250985385894 0.0930108141555412 1.0 0.5140728203133679 2 O94813 1 +Olfactory bulb interneuron differentiation 0.9664249261348372 1.6797250985385894 0.0930108141555412 1.0 0.5140728203133679 2 O94813 1 +Regulation of chemokine mediated signaling pathway 0.9664249261348372 1.6797250985385894 0.0930108141555412 1.0 0.5140728203133679 2 O94813 1 +Cerebral cortex tangential migration 0.9664249261348372 1.6797250985385894 0.0930108141555412 1.0 0.5140728203133679 2 O94813 1 +Roundabout signaling pathway 0.9664249261348372 1.6797250985385894 0.0930108141555412 1.0 0.5140728203133679 2 O94813 1 +Neuron projection regeneration 0.6205990993371456 1.6772413580563734 0.0934952946166045 1.0 0.5141886782381021 14 Q96G23,Q14118,P10586 3 +Animal organ formation 0.7035181004916317 1.676456592654467 0.0936487918084687 1.0 0.5141886782381021 8 P98164 1 +Acute phase response 0.9656191243620752 1.676432116779618 0.0936535824471673 1.0 0.5141886782381021 2 P02786 1 +Positive regulation of protein kinase b signaling 0.5679679024857937 1.6719996979351233 0.0945243816375716 1.0 0.5179905198160301 20 P00533,Q07021,Q13641,P98164 4 +Cellular response to inorganic substance 0.4885190275276687 1.6709683299487614 0.0947279334674136 1.0 0.5182584572233517 48 Q99538,O95831,Q92542,Q04656,Q14168,Q06787,P00533,P05067,Q9NQ11 9 +Detection of other organism 0.9640075208165482 1.6698454541840153 0.0949499445871422 1.0 0.5186263476960288 2 P04439 1 +Protection from natural killer cell mediated cytotoxicity 0.9640075208165482 1.6698454541840153 0.0949499445871422 1.0 0.5186263476960288 2 P04439 1 +Central nervous system neuron development 0.6058759821210224 1.6679832184883574 0.0953190581688265 1.0 0.5202185080191171 15 P51805,O94813,O14786 3 +Glomerular epithelial cell development 0.8215763832952796 1.666755921784726 0.0955629481788569 1.0 0.5207015273940643 4 O00592 1 +Late endosome to vacuole transport via multivesicular body sorting pathway 0.749743529661156 1.66603517142583 0.0957064093567703 1.0 0.5210595901779649 6 Q9UK41,Q92783,Q9H3S7,Q9BRG1 4 +Muscle cell cellular homeostasis 0.7158538900148108 1.6642974587988897 0.0960530000020929 1.0 0.5216752074667965 7 P13473,P10253 2 +Positive regulation of immune response 0.446050862082341 1.663423734988397 0.0962276452881467 1.0 0.5217780572177666 85 P01889,Q9NUD5,O15400,P07947,O43405,Q9NRA0,Q07021,Q07666,Q06481,P51809,Q7KYR7,Q5ZPR3,P04439,Q9BY67,Q6PIJ6,Q08722,P02786,P11279,Q92692 19 +Regulation of macrophage activation 0.7001549028002234 1.6612979833790191 0.0966536148461643 1.0 0.5236641282934463 8 P01130,P14174,P53634 3 +Coronary artery morphogenesis 0.8200085788029571 1.660453928225753 0.0968231689494316 1.0 0.5238916056077002 4 P98164 1 +Cerebellar purkinje cell layer formation 0.8198596348979271 1.65985510617485 0.0969436047264593 1.0 0.5238916056077002 4 P04062,Q04656 2 +Aortic valve morphogenesis 0.8197847949714794 1.6595542077263925 0.0970041669731545 1.0 0.5238916056077002 4 O94813 1 +Heart valve development 0.6847499813752992 1.6595337853570111 0.0970082785077821 1.0 0.5238916056077002 9 O94813,Q9Y6N7 2 +Microglia differentiation 0.9613215149073372 1.6588657040308497 0.0971428568763697 1.0 0.5241959958014732 2 P05067 1 +Chondroitin sulfate proteoglycan biosynthetic process 0.7707549619655909 1.6575354679815433 0.0974112642482627 1.0 0.524788971610326 5 Q9P2E5,Q8N6G5 2 +Negative regulation of cell differentiation 0.4513962077638156 1.6567675491314449 0.0975664801702691 1.0 0.524788971610326 89 P01130,Q99523,Q96G23,P06756,Q9P265,Q8N4Q0,Q15375,Q92673,P67809,Q06481,P00533,O14786,P05067,P51805,P05556 15 +Lens development in camera type eye 0.6555950788094506 1.6559831673262315 0.0977252276761448 1.0 0.524788971610326 11 Q14517,P29317,Q12959,P35222,P08670 5 +Positive regulation of protein catabolic process in the vacuole 0.9680279419666842 1.6504585568959214 0.0988491829699973 1.0 0.5280772216991445 3 P01130,P98164 2 +Regulation of amyloid fibril formation 0.6977201962939064 1.650310818638856 0.098879380677616 1.0 0.5280772216991445 8 P01130,P05067 2 +Positive regulation of triglyceride biosynthetic process 0.9591727101799656 1.6500802290276508 0.0989265279224544 1.0 0.5280772216991445 2 P01130 1 +High density lipoprotein particle clearance 0.9591727101799656 1.6500802290276508 0.0989265279224544 1.0 0.5280772216991445 2 P01130 1 +Regulation of triglyceride biosynthetic process 0.9591727101799656 1.6500802290276508 0.0989265279224544 1.0 0.5280772216991445 2 P01130 1 +Negative regulation of erbb signaling pathway 0.6686422502886427 1.6497421534253525 0.098995684607777 1.0 0.5280772216991445 10 Q99538,Q9BRG1 2 +Long term memory 0.8172863335589924 1.6495059422974945 0.0990440268092844 1.0 0.5280772216991445 4 P01130,Q96KQ7 2 +Negative regulation of keratinocyte proliferation 0.7686109532056473 1.6486647014440292 0.0992163454813213 1.0 0.5280856485096095 5 Q6YHK3 1 +Regulation of protein localization to synapse 0.8168067798555956 1.6475766099320444 0.0994395834704755 1.0 0.5280856485096095 4 Q9BQT9 1 +Polyol biosynthetic process 0.627234376685405 1.646663512523605 0.099627227934629 1.0 0.5282450012799715 13 P04062,Q13510,Q9NRA0 3 +Synaptic vesicle membrane organization 0.7679495322689979 1.6459269438646416 0.0997788009034974 1.0 0.5285708988026968 5 O43760,O95721,Q5SQN1 3 +Lymphocyte costimulation 0.8160897189998247 1.644691342799656 0.1000334790278349 1.0 0.5285708988026968 4 Q9NPF0 1 +Sphingomyelin catabolic process 0.8160122663686071 1.6443796648855038 0.1000978028772348 1.0 0.5285708988026968 4 Q92485 1 +Regulation of vacuole organization 0.6267338937152124 1.644059754124989 0.1001638601088241 1.0 0.5285708988026968 13 Q14108,Q9NUM4 2 +Purine nucleotide transport 0.6267334152842314 1.6440572647580909 0.1001643742655615 1.0 0.5285708988026968 13 Q8TB61,Q99808,Q08722,P41440 4 +Multicellular organism growth 0.5041136240607347 1.6436839475546887 0.1002415034581625 1.0 0.5285708988026968 33 Q99538,O75844,O75882,P05067,Q9HCL2 5 +Regulation of myelination 0.6013656812553707 1.643096672584076 0.1003629332146973 1.0 0.5285708988026968 15 P53634,Q15058,P42345,Q13614,Q12959,Q9Y2Y6,Q14118 7 +Regulation of heterotypic cell cell adhesion 0.8156507380872217 1.642924761778917 0.1003985010707002 1.0 0.5285708988026968 4 O75955,P41440 2 +Tangential migration from the subventricular zone to the olfactory bulb 0.965279882870798 1.6400857415626249 0.1009873406280617 1.0 0.5304209693489572 3 O94813 1 +Keratan sulfate metabolic process 0.9650725416442766 1.6393029658639846 0.1011501786692585 1.0 0.5305908193597583 3 P16278,P15586 2 +Regulation of phospholipid metabolic process 0.6373289799752438 1.6378694380265968 0.1014489325596339 1.0 0.5313974234917507 12 P01130,Q8WTV0 2 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.9642665233745296 1.6362598125345986 0.1017852230537614 1.0 0.5318103889348729 3 P10321,P04439 2 +Positive regulation of oxidoreductase activity 0.6657912979213965 1.6361541455572264 0.1018073304988722 1.0 0.5318103889348729 10 Q8WTV0,P08754,Q04656,P00374,Q9P0J1,P04899,P0DP25 7 +Negative regulation of response to wounding 0.6511004781898847 1.6339282715188557 0.1022739126284824 1.0 0.5329064905969012 11 Q96G23,O14936,O94898,P55011,Q6YHK3 5 +Negative regulation of lipid localization 0.7646808706705446 1.6323894088626971 0.1025974788514609 1.0 0.5329064905969012 5 P06756,P31751 2 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.9631907272855492 1.6321976339301971 0.1026378590705188 1.0 0.5329064905969012 3 Q9UIQ6 1 +Glycolipid transport 0.963020235092491 1.631553811098868 0.1027735151792106 1.0 0.5329064905969012 3 P07602 1 +Response to corticosteroid 0.5155275648543317 1.6310944455603404 0.1028703925276639 1.0 0.5329064905969012 30 P04062,P16278,P19021,O94813 4 +Cellular response to increased oxygen levels 0.7083154254849966 1.6310798200593322 0.1028734781478795 1.0 0.5329064905969012 7 Q15904,Q8N511 2 +Negative regulation of transforming growth factor beta receptor signaling pathway 0.6500466603527266 1.6287502009974826 0.1033659107445135 1.0 0.5329064905969012 11 Q9NYA4,Q92896,Q6YHK3 3 +Regulation of chaperone mediated autophagy 0.8119927060329513 1.6281969602379147 0.1034831291424422 1.0 0.5329064905969012 4 P10619 1 +Response to tumor cell 0.7076022045820152 1.627932020388025 0.1035393009214868 1.0 0.5329064905969012 7 Q04721,P04439,Q92692 3 +Hindbrain development 0.4883963413899352 1.6275197330297446 0.1036267610899335 1.0 0.5329064905969012 43 O95456,P54802,Q7Z4L5,Q15058,Q92542,Q04656,Q5KU26,P04062,O15228,Q14103,P18887,O75882,P05556 13 +Magnesium ion transport 0.8115394231764141 1.6263711306328488 0.1038707283884983 1.0 0.5329064905969012 4 Q6P4Q7,Q8IUH4 2 +Artery development 0.5981811511485569 1.6254861364086923 0.1040590154759464 1.0 0.5329064905969012 15 P98164,P01130,Q9Y6N7,Q07954 4 +Myoblast fusion 0.7069373485637536 1.6249969018935586 0.1041632189658903 1.0 0.5329064905969012 7 O75955,P05556,P41440 3 +Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.8110722923945075 1.6244893294716862 0.1042714158937569 1.0 0.5329064905969012 4 Q92783,Q9H3S7,Q9BRG1 3 +Negative regulation of neuron death 0.4871557956201343 1.6242827487817637 0.1043154773210222 1.0 0.5329064905969012 44 Q99538,P50897,P04062,Q92673,O14786,Q9NQ11 6 +Positive regulation of peptidyl serine phosphorylation 0.5532618905554956 1.6240953874389668 0.1043554522567946 1.0 0.5329064905969012 21 P02786,P05067,P14174 3 +Regulation of cell adhesion mediated by integrin 0.7065926910454857 1.6234750589569138 0.1044878907844517 1.0 0.5329064905969012 7 O00592 1 +Negative regulation of cellular response to growth factor stimulus 0.6105056668810267 1.6231920046786603 0.1045483664734931 1.0 0.5329064905969012 14 O94813,Q92673,O14936,P98164,P46934,O14964 6 +Cerebellar purkinje cell layer morphogenesis 0.7389550908491629 1.6203069317401744 0.1051663606315735 1.0 0.5329064905969012 6 Q04656,P04062,Q7Z4L5 3 +Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.7389286222164478 1.6201945353337734 0.1051904949395066 1.0 0.5329064905969012 6 O43657 1 +Positive regulation of toll like receptor signaling pathway 0.7389031642605907 1.6200864297325197 0.1052137120515614 1.0 0.5329064905969012 6 O43164,O75955,P41440 3 +Regulation of granulocyte chemotaxis 0.675955206342931 1.6187806574405117 0.1054944653103355 1.0 0.5329064905969012 9 Q07021,O94813,Q00013 3 +Phosphatidylcholine catabolic process 0.9594304137560448 1.617994701698154 0.1056637395012671 1.0 0.5329064905969012 3 P01130,Q8NCC3 2 +Detection of external biotic stimulus 0.9594304137560444 1.6179947016981528 0.1056637395012674 1.0 0.5329064905969012 3 P04439,P01889 2 +Positive regulation of rho protein signal transduction 0.809377759783106 1.617661409984195 0.10573558679671 1.0 0.5329064905969012 4 Q9Y6N7 1 +Regulation of collagen metabolic process 0.8092570951590051 1.6171751097398717 0.1058404874737402 1.0 0.5329064905969012 4 P17301,P05556 2 +Cellular response to calcium ion 0.6093645163971169 1.6170621840662829 0.1058648586744295 1.0 0.5329064905969012 14 Q99538 1 +Cellular response to lipoprotein particle stimulus 0.809102051974009 1.6165502389874238 0.1059754005986373 1.0 0.5329064905969012 4 P01130,O15118 2 +Cerebral cortex cell migration 0.6475153091065143 1.616301274478788 0.106029191422299 1.0 0.5329064905969012 11 P00533,O94813,Q9Y6N7 3 +Protein localization to early endosome 0.6901266518893209 1.6159717030467542 0.1061004313325864 1.0 0.5329064905969012 8 Q92673 1 +Positive regulation of protein binding 0.5211625545657439 1.6159504177629858 0.1061050336478914 1.0 0.5329064905969012 28 P05067,P41440,Q07954,O14786 4 +Regulation of actin cytoskeleton reorganization 0.6473999557785044 1.615733616414862 0.1061519195683173 1.0 0.5329064905969012 11 Q04721,Q9Y624,O14786 3 +Appendage morphogenesis 0.6088569017434684 1.6143342400934164 0.1064549470244016 1.0 0.5340277357466614 14 P42892,Q5SZK8,Q9NX62 3 +Anatomical structure homeostasis 0.4828546836665559 1.6133833988371766 0.1066612375902635 1.0 0.5346623891772225 47 O14773,Q16625,P51790,P10253,P13473,P02786,P38571,P11166,P78310,Q9Y624,P05556 11 +Synapse organization 0.4317324297972069 1.6076103109031512 0.1079205525730127 1.0 0.53680180982024 79 Q9Y6W5,Q13614,Q14118,P05067,Q99538,O15031,Q14012,Q9BQT9,Q13641,P56545,P10586,Q9Y4F1,O14786,P46934,Q9UQB8,Q12959,Q15375,O15228,P07437,O00560,Q05086 21 +Regulation of cholesterol metabolic process 0.659677918953247 1.6069566200396963 0.1080638845074475 1.0 0.5368748361519001 10 P01130,Q9H2C2,P34913 3 +Immune response to tumor cell 0.758445696700626 1.6065301370675211 0.1081574787582599 1.0 0.5369417945465618 5 P04439,Q92692 2 +Regulation of oxidoreductase activity 0.5570446016977131 1.6047512590679682 0.108548556331363 1.0 0.5384844000982941 20 Q9NRA0,P08754,Q04656,P0DP25,P00533,P04899,P06280,Q8WTV0 8 +Negative regulation of protein maturation 0.7347037026806111 1.6022412447709355 0.1091022727483441 1.0 0.5400320767794702 6 Q9BXS4 1 +Negative regulation of immune system process 0.4802218592989073 1.6007987392321426 0.1094215029502927 1.0 0.5412124817511896 48 P01130,P14174,P04439,P01889,Q08722,O94813,P10644,Q9HCL2 8 +Positive regulation of neurogenesis 0.480138644772594 1.6000923234934858 0.1095781037138712 1.0 0.5412440962672074 48 Q16706,O15031,P55209,O94813,Q14118,O14786,Q9Y6N7,P51805,P98164,Q13049 10 +Regulation of dna methylation 0.6580545210316397 1.5991895764612627 0.1097784857025929 1.0 0.5412440962672074 10 Q96KQ7,Q8NB78 2 +Dna catabolic process endonucleolytic 0.7010800349086788 1.5991067168850146 0.1097968924733501 1.0 0.5412440962672074 7 O00115 1 +Negative regulation of lipid transport 0.8046471502797633 1.5985867926216315 0.1099124462876259 1.0 0.5412440962672074 4 P06756,P31751 2 +Renal system process 0.5928240225171459 1.5957885476259226 0.1105360110563467 1.0 0.54141666628257 15 Q99538,Q96J84,P22694,P43121,P04899,Q7LG56,P17612 7 +Regulation of membrane invagination 0.7556051078743571 1.5947342140065277 0.1107716836409313 1.0 0.54141666628257 5 P17301,Q06481 2 +Regulation of fc gamma receptor signaling pathway involved in phagocytosis 0.9452054794520602 1.5929453616734015 0.1111724488557419 1.0 0.54141666628257 2 Q06481 1 +Regulation of cell projection organization 0.5156848578949352 1.5923087638902806 0.1113153447317474 1.0 0.54141666628257 140 Q9P265,Q9P273,Q9UL15,Q9Y6W5,Q16625,P51805,Q9ULH0,P98155,P17301,Q9H4M9,P11233,Q32P28,O15031,O94898,Q14108,Q96G23,O14641,Q9NUM4,Q6PIJ6,Q9NQX7,P29317,Q04656,P10586,Q9NV96,P51116,O14786,P46934,Q9UQB8,O94813,P51114,O00592,Q15375,Q06787,Q8WWV3,Q9Y277,Q05086,Q9Y6N7,P08670 38 +Positive regulation of stress activated protein kinase signaling cascade 0.5789872714172075 1.5915654019835697 0.1114823891674767 1.0 0.54141666628257 16 P05067,Q8TDY2,O00560 3 +Lipid translocation 0.6843280625002613 1.589678043045907 0.111907395422153 1.0 0.54141666628257 8 Q9NV96,P33527,Q4KMQ2,Q7Z3C6 4 +Chemical synaptic transmission postsynaptic 0.6417896817432525 1.5880874493334474 0.1122665659368682 1.0 0.54141666628257 11 Q14168,P05067,Q9UQB8,Q99808 4 +Regulation of postsynaptic membrane potential 0.6417896817432525 1.5880874493334474 0.1122665659368682 1.0 0.54141666628257 11 Q14168,P05067,Q9UQB8,Q99808 4 +Negative regulation of amyloid precursor protein biosynthetic process 0.9513168952572528 1.5873293812395493 0.1124380641578093 1.0 0.54141666628257 3 Q9Y287 1 +Transforming growth factor beta production 0.8017107845326639 1.5867373925522688 0.1125721337097125 1.0 0.54141666628257 4 P06756 1 +Coronary vasculature morphogenesis 0.7535461321879511 1.5861782845970611 0.1126988723489068 1.0 0.54141666628257 5 P98164 1 +Cerebellar cortex morphogenesis 0.6552084106298723 1.585558838460211 0.1128394197597362 1.0 0.54141666628257 10 Q04656,P04062,Q7Z4L5 3 +Regulation of erbb signaling pathway 0.5777712131789002 1.5845905102625182 0.1130594024630171 1.0 0.54141666628257 16 Q99538,Q9BRG1 2 +Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules 0.8011287288363331 1.5843877286192125 0.1131055127244748 1.0 0.54141666628257 4 P19022,O00192,P98194 3 +Adenylate cyclase inhibiting g protein coupled receptor signaling pathway 0.6681231729518045 1.5823572232904384 0.1135680442319657 1.0 0.54141666628257 9 P04899,P07602,P63096 3 +Axonogenesis involved in innervation 0.9425194735428462 1.5819535237830975 0.1136601807760939 1.0 0.54141666628257 2 P42892 1 +Regulation of retinal ganglion cell axon guidance 0.9425194735428456 1.5819535237830955 0.1136601807760944 1.0 0.54141666628257 2 O94813 1 +Branching involved in salivary gland morphogenesis 0.9425194735428444 1.5819535237830886 0.1136601807760959 1.0 0.54141666628257 2 Q14118 1 +Heart morphogenesis 0.4858199652237653 1.578031858680507 0.1145582909669484 1.0 0.54141666628257 36 O94813,P10253,O75844,O14786,P16870,Q9Y6N7,P98164 7 +Skin epidermis development 0.5650983162224067 1.5767683286502694 0.1148488416160755 1.0 0.54141666628257 18 Q08J23,Q04656,O75844,P00533,Q6YHK3 5 +Regulation of receptor mediated endocytosis 0.5034530109851065 1.5731416759506327 0.1156860166838109 1.0 0.54141666628257 31 P06756,P50897,O75955,O00560,P41440,P05067 6 +Renal system vasculature morphogenesis 0.94010206822455 1.5720600910264553 0.1159366158503334 1.0 0.54141666628257 2 O14786 1 +Renal system vasculature development 0.94010206822455 1.5720600910264553 0.1159366158503334 1.0 0.54141666628257 2 O14786 1 +Fertilization 0.4899538650432535 1.5714717207016995 0.1160731181130012 1.0 0.54141666628257 34 P45880,Q08431,P07686,O60266,Q96KQ7,Q92692 6 +Glucosylceramide metabolic process 0.7976850750037658 1.5704807231820377 0.1163033156032931 1.0 0.5416711752420225 4 Q16739 1 +Neutral amino acid transport 0.6944394747132037 1.569686054684297 0.1164881671043072 1.0 0.5417791089056675 7 P08195,Q9H2J7,Q96QD8 3 +N glycan processing 0.7971223832671259 1.5682074386170517 0.116832728976111 1.0 0.542628516699859 4 P33908 1 +Regulation of axonogenesis 0.5106459618381711 1.567845009108464 0.1169173079358045 1.0 0.5426452893253201 29 Q9P265,O94813,Q15375,O14786,P51805,Q9Y6N7 6 +Lymphocyte migration 0.6371375751469933 1.5651073512222138 0.1175577401849412 1.0 0.5443917597753203 11 P04062,P05067 2 +Negative regulation of amyloid beta clearance 0.9450168842028466 1.5635015134622736 0.117934679984756 1.0 0.5443917597753203 3 P15260 1 +Regulation of amyloid precursor protein catabolic process 0.5869407163639598 1.5630704857168922 0.1180360167786822 1.0 0.5443917597753203 15 Q92673,P15260 2 +Positive regulation of immune system process 0.495795288300378 1.5626286474299675 0.1181399660727977 1.0 0.5443917597753203 127 P14174,P01889,Q4KMQ2,O15400,P05067,P07947,Q99538,P17301,O43405,Q9NRA0,P53634,Q07021,Q96J02,Q07666,Q06481,P51809,Q7KYR7,Q5ZPR3,Q9NPF0,P04439,Q9BY67,Q08722,P02786,P11279,Q14254,Q04721,P30825,Q9HCL2,Q92692 29 +Regulation of mast cell activation involved in immune response 0.7478482798891077 1.562476660320545 0.1181757399865439 1.0 0.5443917597753203 5 P51809,Q9NRA0 2 +Regulation of neuron projection regeneration 0.7244272005158982 1.5584706669576591 0.1191217162137354 1.0 0.5450549720758217 6 Q96G23,P10586 2 +Cardiac chamber development 0.5227403696881211 1.5575937961606336 0.1193295702601606 1.0 0.5450549720758217 25 O94813,O75844,O14786,P16870,Q9Y6N7,P98164 6 +B cell proliferation 0.6490862386646434 1.5561797965665791 0.1196653441803781 1.0 0.5450549720758217 10 P02786,Q9NPF0 2 +Positive regulation of cellular response to insulin stimulus 0.6768974943691359 1.555896000344984 0.1197328246442879 1.0 0.5450549720758217 8 Q92673 1 +Detection of stimulus 0.5353900429965358 1.555465343451305 0.1198352822576207 1.0 0.5450549720758217 22 P17301,P04439,P01889,Q9BY67,P19022,P0DP25,Q8WTV0,P29992,P35222 9 +Outflow tract septum morphogenesis 0.9427727028479304 1.5550104782518424 0.1199435738252825 1.0 0.5450549720758217 3 P98164,Q9Y6N7 2 +Wound healing 0.4338934457530462 1.5547119153983016 0.1200146955226535 1.0 0.5450549720758217 69 P17301,Q04721,P42785,Q16625,Q86YV9,Q4KMQ2,P43121,Q14344,Q14118,O14936,Q9Y3E7,Q13308,Q9Y6X5,Q6YHK3,Q9UNN8,Q8WTV0,Q9Y624,P05556 18 +G protein coupled receptor signaling pathway 0.4594515840397686 1.5537865220960432 0.1202353465120371 1.0 0.5450549720758217 58 Q99523,Q9Y6W5,P22694,Q14344,P07602,Q8NCG7,P63096,P16870,O43865,P48960,Q9NRA0,Q92673,P04899,O60266,Q06481,P11717,P0DP25,P08754,P09471,Q15043,P42892,O60291 22 +Protein mannosylation 0.7935325949286411 1.553698946945454 0.1202562443915247 1.0 0.5450549720758217 4 O43505 1 +Protein o linked mannosylation 0.7935325949286411 1.553698946945454 0.1202562443915247 1.0 0.5450549720758217 4 O43505 1 +Lipid homeostasis 0.5007114538830734 1.5529421264261472 0.1204369614267808 1.0 0.5450549720758217 31 Q9H4M9,P01130,O15260,Q96CP7,P61916,Q9HCL2,Q86YV9,O15118,P34913,Q8WTV0,O15254,Q9NQ11 12 +Ornithine transport 0.935267257587971 1.5522716723868135 0.1205972330042051 1.0 0.5450549720758217 2 P30825 1 +T cell migration 0.6760908301714119 1.5522227726376008 0.120608928984234 1.0 0.5450549720758217 8 P05067 1 +Lamellipodium assembly 0.527508473431817 1.55174755382261 0.1207226394050335 1.0 0.5450549720758217 23 Q9H4A6,Q9Y6W5,P53365,P29317,Q16625,O94813,Q04656,Q12792,P47756,P05556 10 +Heart field specification 0.9416336316536436 1.5507001421674718 0.120973560444995 1.0 0.5450549720758217 3 P98164 1 +Adipose tissue development 0.6088046902552013 1.5503299879835282 0.1210623332012554 1.0 0.5450549720758217 13 Q92673,O15173,P35610 3 +Dendrite development 0.4644471416017829 1.5502897018060136 0.1210719979658925 1.0 0.5450549720758217 55 Q9NUM4,Q06787,Q9Y4F1,Q8WWV3,O14786,P05067,Q9ULH0,P46934,Q13641,P05556,P98155 11 +Positive regulation of mitophagy 0.7925472947345837 1.549715073534021 0.1212099185875117 1.0 0.5450549720758217 4 P21796 1 +Receptor catabolic process 0.6199512330239603 1.5495348231813568 0.1212532070715313 1.0 0.5450549720758217 12 Q99538,Q96J02,P46934,Q9H3E2 4 +Leucine transport 0.9344614558152078 1.5489734721423436 0.1213880972435237 1.0 0.5450549720758217 2 Q9H2J7 1 +Alanine transport 0.9344614558152068 1.548973472142339 0.1213880972435248 1.0 0.5450549720758217 2 Q96QD8 1 +Cell fate commitment 0.524357602763862 1.548872862634328 0.1214122856615582 1.0 0.5450549720758217 24 Q04721,P07711,O14786,Q96KQ7,P05556 5 +Rna stabilization 0.5115956685984626 1.5485723156197115 0.1214845652679388 1.0 0.5450549720758217 28 P35637,Q14011,Q9NRA8,Q13151,Q92804,Q96HR8,Q08J23,O60506,P67809,Q14103,P98175 11 +Cellular response to acid chemical 0.5842378348352238 1.5480034164232106 0.1216214739661909 1.0 0.5450549720758217 15 Q9Y2Q5,Q9UQB8,Q04656,P00533,Q14103,Q99729 6 +Collagen biosynthetic process 0.7442567667967209 1.547518838068213 0.1217381855212167 1.0 0.5450549720758217 5 P17301,Q92791 2 +Folate import across plasma membrane 0.9339242546333668 1.5467746600413204 0.121917592605504 1.0 0.5450549720758217 2 P98164 1 +Xenobiotic transmembrane transport 0.9339242546333596 1.5467746600412926 0.1219175926055107 1.0 0.5450549720758217 2 Q9NV96 1 +Regulation of phosphatidylinositol 3 kinase signaling 0.6193364825613479 1.546396036143758 0.1220089508831969 1.0 0.5450549720758217 12 P00533,P46934,Q8NDZ4 3 +Pulmonary valve morphogenesis 0.940354648038688 1.545859928589281 0.122138399962961 1.0 0.5450549720758217 3 O94813,Q9Y6N7 2 +Regulation of phospholipid catabolic process 0.7915668807149678 1.545750253386261 0.1221648954722156 1.0 0.5450549720758217 4 P01130 1 +Sensory perception of mechanical stimulus 0.5407481992043198 1.5450139862214167 0.1223428803835973 1.0 0.5450549720758217 21 P17301,O43405,P07686,Q14108,P98164 5 +Dendrite arborization 0.9396270512023426 1.54310619523164 0.1228050118348993 1.0 0.545168058640699 3 Q13641 1 +Negative regulation of mrna metabolic process 0.4721813394238528 1.5422708701909915 0.1230077845359265 1.0 0.545168058640699 49 P35637,Q9NRA8,Q13151,Q14103,P38159,Q92804,O75494,Q07021,O60506,P22626,P67809,Q06787,Q13242,Q14011,Q99729,Q99728 16 +Chondrocyte differentiation 0.645741132386958 1.5400941409218991 0.1235374077596047 1.0 0.545168058640699 10 Q92896,Q9NX62 2 +Cell substrate adhesion 0.435102232662476 1.539425427109385 0.1237004704550162 1.0 0.545168058640699 68 P17301,P06756,Q9UM22,Q07021,P14543,Q14118,O14936,O95819,O14786,O75882 10 +Regulation of water loss via skin 0.7199627994504525 1.53941216100515 0.1237037070303141 1.0 0.545168058640699 6 Q16739 1 +Membrane fusion involved in viral entry into host cell 0.9320440504969202 1.5390787717743313 0.12378506680802 1.0 0.545168058640699 2 P07711 1 +Mammary gland epithelium development 0.6318483598372481 1.5389199963752762 0.1238238287820667 1.0 0.545168058640699 11 P29317,Q9Y6N7 2 +Positive regulation of protein containing complex disassembly 0.6587611923450889 1.538661149193965 0.123887041675587 1.0 0.545168058640699 9 Q13137 1 +Aminophospholipid transport 0.938267784432668 1.5379614082542417 0.1240580509960318 1.0 0.5453386007775719 3 Q14108 1 +Positive regulation of cell development 0.4349458397324502 1.5378367491534046 0.1240885356887193 1.0 0.5453386007775719 68 Q16706,O15031,Q07021,Q9UQB8,P55209,O94813,Q14118,O14786,Q9Y6N7,P51805,Q9Y624,P98164,Q13049 13 +Positive regulation of cell substrate adhesion 0.5025305474875923 1.5369436269563053 0.1243071147548677 1.0 0.5456884056201929 30 Q53GQ0,Q14185,Q07021,P14543,Q14118,O95819,P46108,O14786 8 +Sprouting angiogenesis 0.5523428156062926 1.5364396908241127 0.1244305785026449 1.0 0.5456884056201929 19 P29317,O94813,P23458,O14786,Q9Y6N7 5 +Fatty acid transmembrane transport 0.6726146069448053 1.5363805851129315 0.1244450655961095 1.0 0.5456884056201929 8 P31751,P23786,P11166 3 +Response to axon injury 0.5458000529898261 1.53502595382448 0.1247774529673924 1.0 0.5460260524457292 20 Q96G23,Q14118,P10586 3 +Phosphatidylinositol 3 kinase signaling 0.5637407713724898 1.5347443137261445 0.1248466461592137 1.0 0.5460260524457292 17 Q8NDZ4,Q07021,P00533,P46934,Q05086 5 +Production of molecular mediator involved in inflammatory response 0.5940700407686769 1.5345404984434077 0.1248967380482397 1.0 0.5460260524457292 14 Q8IV08,Q06481,P51809 3 +Glycerol 3 phosphate metabolic process 0.9307010475423094 1.5335816978469128 0.125132593729399 1.0 0.5465365284758762 2 Q9HCL2 1 +Regulation of stress activated protein kinase signaling cascade 0.4799065962703284 1.5331281423923973 0.1252442848876434 1.0 0.5465365284758762 37 O75844,Q96J02,P00533,O95819,O00560,P05067,Q8TDY2 7 +Regulation of bmp signaling pathway 0.5814670055376191 1.532534389073348 0.1253906181688058 1.0 0.5465365284758762 15 Q04721,Q92673,P98164 3 +Negative regulation of leukocyte chemotaxis 0.9304324469513888 1.5324822850480244 0.1254034658064458 1.0 0.5465365284758762 2 O94813 1 +Regulation of cell cell adhesion mediated by cadherin 0.7881649359400087 1.5319873870908518 0.1255255472581482 1.0 0.5465365284758762 4 P41440 1 +Positive regulation of cell cell adhesion mediated by cadherin 0.7881649359400087 1.5319873870908518 0.1255255472581482 1.0 0.5465365284758762 4 P41440 1 +Defense response to bacterium 0.5244828782827863 1.531699036567061 0.125596720268309 1.0 0.5465365284758762 23 Q5KU26,P29317,P04439,O43405 4 +Sensory organ morphogenesis 0.4799817822750615 1.5307847174337947 0.1258226078666073 1.0 0.5468632411945542 35 Q04721,Q14517,Q96JA1,Q9P273,Q16706,P54802,O14641,Q8N584,P29317,O95140,Q13308,Q15555,P35222,Q8IZL8 14 +Positive regulation of interleukin 1 beta production 0.717742724256071 1.5299252461408253 0.1260352334784116 1.0 0.5471938072333129 6 P05067 1 +Amyloid fibril formation 0.6430864452238468 1.5273120964656517 0.1266834229521722 1.0 0.5484704784402187 10 P01130,P05067 2 +Regulation of axon guidance 0.7866466079754355 1.5258422671901093 0.1270491514888068 1.0 0.5486362198956077 4 O94813,O14786 2 +Positive regulation of cytokine production 0.4224411842139516 1.524499966684692 0.1273838651738821 1.0 0.5489409989145887 72 Q96RD7,P14174,P04439,Q9NRA0,Q9BY67,P15260,O75787,O75955,Q92673,P41440,P05067 11 +Mammary gland epithelial cell proliferation 0.6555303460393906 1.5235427981773024 0.1276229617526385 1.0 0.5489409989145887 9 Q9Y6N7 1 +Nucleotide transmembrane transport 0.642196165341889 1.523022270074534 0.1277531338891187 1.0 0.5489409989145887 10 Q8TB61,Q9H2D1,P41440 3 +L amino acid transport 0.5918909892493132 1.5227290029691547 0.1278265187284835 1.0 0.5489409989145887 14 P08195,Q9Y619,Q96QD8,P30825 4 +Folate transmembrane transport 0.9341751746372904 1.522468253613991 0.1278917941113837 1.0 0.5489409989145887 3 Q9H2D1,P98164 2 +Folic acid transport 0.9341751746372904 1.522468253613991 0.1278917941113837 1.0 0.5489409989145887 3 Q9H2D1,P98164 2 +Positive regulation of dendrite development 0.9338102574148592 1.521086622249086 0.1282381011218654 1.0 0.5489409989145887 3 P98155 1 +Protein kinase c signaling 0.7853052508683029 1.5204121094693797 0.1284074329005311 1.0 0.5489409989145887 4 O75955,P41440 2 +Regulation of autophagy 0.4698902599410871 1.5194197110646877 0.128656883565057 1.0 0.5489409989145887 111 Q9BXS4,Q93050,P27544,P04062,P07602,Q9Y487,Q07820,Q9NYA4,O15269,Q14145,P10619,Q9NNW5,Q96KQ7,Q9NQ11,P08754,O75844,Q13137,P46934,P21796,Q13049,O15118,Q8NHS3 22 +Positive regulation of leukocyte chemotaxis 0.6140387589782533 1.519308672177098 0.1286848178658619 1.0 0.5489409989145887 12 Q99538,Q07021,Q4KMQ2 3 +Autophagy of nucleus 0.7151504140212415 1.5188399276834816 0.1288027929115918 1.0 0.5489409989145887 6 Q8TDY2,Q7Z3C6 2 +Cardiac chamber morphogenesis 0.5789804484392579 1.5186325876131437 0.1288550036941869 1.0 0.5489409989145887 15 O94813,O14786,P16870,Q9Y6N7,P98164 5 +Regulation of vascular permeability 0.6686669124198948 1.5183648128327405 0.1289224570109794 1.0 0.5489409989145887 8 Q16625,O94813 2 +Regulation of synaptic transmission dopaminergic 0.926940639269406 1.5181901171227676 0.1289664781996626 1.0 0.5489409989145887 2 P41440 1 +Positive regulation of toll like receptor 3 signaling pathway 0.926940639269406 1.5181901171227676 0.1289664781996626 1.0 0.5489409989145887 2 P41440 1 +Positive regulation of heterotypic cell cell adhesion 0.926940639269406 1.5181901171227676 0.1289664781996626 1.0 0.5489409989145887 2 P41440 1 +Molting cycle 0.5493439523581082 1.5181316456618308 0.1289812149029565 1.0 0.5489409989145887 19 Q08J23,Q04656,O75844,P00533,Q6YHK3 5 +Mesonephric tubule morphogenesis 0.7847352862133803 1.5181043859030687 0.1289880856927974 1.0 0.5489409989145887 4 Q12959,Q9Y5V3,P35222 3 +Synaptic signaling 0.454241321101363 1.5177293146130226 0.1290826508402056 1.0 0.5489409989145887 100 Q13501,Q13614,O75955,Q14118,P55011,Q8NCG7,P05067,Q99538,P50897,P33176,P51790,Q14168,Q9Y666,P04899,Q9BQT9,P17612,O95721,P0DP25,P29992,P54920,Q13641,P56545,Q4J6C6,Q9Y4F1,O14936,Q5SQN1,Q7L0J3,P05556,Q99808,Q9UQB8,Q92542,O00161,Q06787,O00560,P41440,Q15833 36 +Regulation of protein kinase c activity 0.92667203867849 1.5170907433384406 0.129243775019697 1.0 0.5489409989145887 2 Q8NDZ4 1 +Intestinal lipid absorption 0.9327491117477692 1.5170688057427626 0.1292493130837393 1.0 0.5489409989145887 3 P01130 1 +Visual behavior 0.6819835781932156 1.5143124737070186 0.1299466063676679 1.0 0.5508552535585773 7 P05067 1 +Ventricular septum morphogenesis 0.7836574483785856 1.5137397616009625 0.1300918560604 1.0 0.5511223889486734 4 O94813 1 +Protein lipid complex assembly 0.7137673896643346 1.5129224296148718 0.1302993637797878 1.0 0.5515338723216945 6 P35610,P17612,P22694 3 +Endosome to lysosome transport 0.5130618969415023 1.5123026164147348 0.1304568957602365 1.0 0.5516227857319277 26 Q99523,P20645,O60291,P51149,Q96ED9,Q9UNK0,Q9H270,Q9Y3E7,P51809,Q96L92 10 +Regulation of protein maturation 0.5898245075940689 1.511515430851541 0.1306571801366733 1.0 0.5521213248902805 14 Q9BXS4,Q92896,P22694,Q9Y2Y6,P17612 5 +Urogenital system development 0.4582190020899856 1.5092230633952544 0.1312417882218095 1.0 0.5521939481536681 56 P14543,Q5SZK8,O94813,O75844,O00592,Q15375,P07602,O14786,P98164 9 +Positive regulation of cellular amide metabolic process 0.4372331413085373 1.5091250038198438 0.1312668408996673 1.0 0.5521939481536681 66 P17301,P98179,Q14103,Q9NRA0,O15031,Q07021,P15260,Q567V2,O60506,P51114,Q06787,P67809,P51116,Q14011,Q9Y2R0 15 +Ephrin receptor signaling pathway 0.6521043215972505 1.5074899621017503 0.1316851148730187 1.0 0.5521939481536681 9 Q15375,P29317 2 +Positive regulation of nf kappab transcription factor activity 0.4945372104862982 1.5072937046687171 0.1317353905203302 1.0 0.5521939481536681 31 P02786,O75955,P41440,P05067,Q14254 5 +Parasympathetic nervous system development 0.9242546333601932 1.5071966166265338 0.1317602672515878 1.0 0.5521939481536681 2 O14786 1 +Trigeminal nerve morphogenesis 0.9242546333601932 1.5071966166265338 0.1317602672515878 1.0 0.5521939481536681 2 O14786 1 +Facial nerve structural organization 0.9242546333601932 1.5071966166265338 0.1317602672515878 1.0 0.5521939481536681 2 O14786 1 +Facial nerve morphogenesis 0.9242546333601932 1.5071966166265338 0.1317602672515878 1.0 0.5521939481536681 2 O14786 1 +Cranial nerve structural organization 0.9242546333601932 1.5071966166265338 0.1317602672515878 1.0 0.5521939481536681 2 O14786 1 +Negative regulation of axon extension involved in axon guidance 0.9242546333601932 1.5071966166265338 0.1317602672515878 1.0 0.5521939481536681 2 O14786 1 +Trigeminal nerve development 0.9242546333601932 1.5071966166265338 0.1317602672515878 1.0 0.5521939481536681 2 O14786 1 +Cranial nerve morphogenesis 0.9242546333601932 1.5071966166265338 0.1317602672515878 1.0 0.5521939481536681 2 O14786 1 +Glycolipid biosynthetic process 0.600558445992202 1.506932096518894 0.1318280633354658 1.0 0.5521939481536681 13 Q16739,O60512 2 +Sterol import 0.9299953309877718 1.5066411230507002 0.1319026705936035 1.0 0.5521939481536681 3 P01130 1 +Regulation of presynapse organization 0.711627544399493 1.5037622044640258 0.1326426061319177 1.0 0.5521939481536681 6 P05067,Q9BQT9 2 +Transport of virus 0.6795739132925562 1.5035728605888774 0.1326913834510117 1.0 0.5521939481536681 7 P07711 1 +Prostate gland development 0.7115320927983295 1.5033534689463113 0.1327479188154081 1.0 0.5521939481536681 6 P07602 1 +Nucleoside triphosphate catabolic process 0.6651758207374736 1.5024111178870307 0.1329909668214459 1.0 0.5521939481536681 8 Q9NQZ7,Q92484,Q9H773 3 +Negative regulation of gliogenesis 0.6651382369781274 1.502239257303916 0.1330353296422382 1.0 0.5521939481536681 8 P01130,Q96G23,P30536,Q9Y2Y6,P35222 5 +Skin morphogenesis 0.9229116304055922 1.50170010776047 0.1331745760633726 1.0 0.5521939481536681 2 P04062 1 +Positive regulation of transmission of nerve impulse 0.9229116304055922 1.50170010776047 0.1331745760633726 1.0 0.5521939481536681 2 P04062 1 +Xenobiotic transport 0.7111370436724828 1.5016617050240275 0.1331844986595025 1.0 0.5521939481536681 6 P41440,Q9NV96,P33527,P11166 4 +Regulation of inflammatory response 0.4673406597751118 1.5005356419753006 0.1334757081481561 1.0 0.5521939481536681 49 Q92485,P17301,P01130,P53634,Q08722,P04062,P51809,Q8NCG7,P05067 9 +Regulation of cell size 0.4713053619345335 1.4997005464046531 0.133691988979772 1.0 0.552619833133662 45 Q8IWT6,Q8N0X7,Q9P265,Q86VI3,P51790,P42345,Q4KMQ2,Q04656,Q9BXP2,Q15375,Q9Y666,Q8TDY2,P55011,O14786,P51805 15 +Negative regulation of low density lipoprotein receptor activity 0.9223744292237538 1.4995015592367595 0.1337435645095195 1.0 0.552619833133662 2 P05067 1 +Extracellular matrix assembly 0.6641350070723083 1.4976509002825362 0.1342239748011646 1.0 0.5529050578946261 8 Q14118,Q04656 2 +Serine transport 0.779304909304622 1.496107019743919 0.1346257689204444 1.0 0.5529050578946261 4 Q96QD8,Q96NB2 2 +Toll like receptor 4 signaling pathway 0.9271896829661456 1.4960156531510331 0.1346495761380084 1.0 0.5529050578946261 3 Q06481,P41440 2 +Regulation of toll like receptor 4 signaling pathway 0.9271896829661456 1.4960156531510331 0.1346495761380084 1.0 0.5529050578946261 3 Q06481,P41440 2 +Positive regulation of cell adhesion molecule production 0.9271896829661456 1.4960156531510331 0.1346495761380084 1.0 0.5529050578946261 3 Q5KU26,P41440 2 +Cell fate determination 0.7792064716009457 1.4957081008560345 0.1347297383644981 1.0 0.5529050578946261 4 Q04721,Q07820 2 +Regulation of response to external stimulus 0.531003454330754 1.495488345119636 0.1347870393755224 1.0 0.5529050578946261 160 Q92485,P14174,P01889,P80303,Q4KMQ2,P04062,Q8NCG7,P05067,P51805,Q99538,P17301,O43405,P53634,Q07021,Q96J02,O94898,Q06481,P51809,Q13641,P01130,Q96G23,P04439,Q9BY67,Q08722,O75844,P10586,O43657,Q92692,O14936,Q9Y6X5,O14786,P11279,Q00013,O94813,Q6YHK3,Q9Y6N7 36 +Lipophagy 0.7317739299526312 1.4954287727428766 0.1348025760369768 1.0 0.5529050578946261 5 O15269,P51149 2 +Regulation of membrane protein ectodomain proteolysis 0.730727479261621 1.4910551954026496 0.1359470042139954 1.0 0.5551067898923481 5 O43847,O94898 2 +Regulation of defense response to virus 0.5448931596105208 1.4908984108574328 0.1359881686744704 1.0 0.5551067898923481 19 O75844,Q07021,O43657 3 +Humoral immune response mediated by circulating immunoglobulin 0.9202256244963748 1.4907077304649707 0.1360382456053228 1.0 0.5551067898923481 2 Q9UQ84 1 +Negative regulation of innate immune response 0.6220487515666988 1.4902365119489238 0.1361620591811629 1.0 0.5551067898923481 11 P04439 1 +Transmembrane receptor protein tyrosine kinase signaling pathway 0.4458191934814809 1.4893292097599418 0.1364006995705124 1.0 0.5551067898923481 96 Q99523,P00533,P07947,Q99538,O95470,Q92673,O94898,P04899,P11717,O14654,P29317,Q8WWQ0,O00459,O14786,P46934,Q15043,Q9UQB8,P31751,Q9BRG1,Q15375,Q07954,Q9Y6N7 22 +Response to bmp 0.5383220820417907 1.4883827157379144 0.1366499921709227 1.0 0.5551067898923481 20 Q04721,Q92673,P98164 3 +External encapsulating structure organization 0.4791072452926787 1.4874647686454925 0.1368921016251547 1.0 0.5551067898923481 34 Q07954,O75718,P14543,Q04656,O75955,Q14118,P41440,P05067,Q92791 9 +Regulation of coagulation 0.729758321539063 1.487003767396934 0.1370138159288445 1.0 0.5551067898923481 5 Q9UNN8,Q9Y6X5 2 +Keratinocyte proliferation 0.6476952893179894 1.4867997078787176 0.1370677187042324 1.0 0.5551067898923481 9 Q04721,Q6YHK3 2 +Regulation of keratinocyte proliferation 0.6476952893179894 1.4867997078787176 0.1370677187042324 1.0 0.5551067898923481 9 Q04721,Q6YHK3 2 +Response to growth factor 0.4884085441603382 1.4864505206231855 0.1371599952375364 1.0 0.5551067898923481 127 Q99523,P00533,P50402,Q9H223,P05067,P07947,Q9ULH0,Q99538,Q9NYA4,Q92673,Q06481,P98164,Q92896,P29317,Q04656,Q9H3E2,O14936,O14786,P46934,P05556,Q04721,Q92859,O94813,O00560,Q6YHK3,Q05086,Q9Y6N7 27 +Anatomical structure maturation 0.4733706553444742 1.485893138258265 0.1373073888709339 1.0 0.5551067898923481 39 O14965,Q8TEL6,P17252,Q08J23,O75787,P04062,Q14118,P17612,P05067,O75503 10 +Negative regulation of endocytosis 0.5965316030059187 1.4856760882478466 0.1373648183923204 1.0 0.5551067898923481 13 Q9UKS6,P06756,O00560,P05067 4 +T cell tolerance induction 0.918345420359931 1.4830136863826022 0.1380707745116995 1.0 0.5551067898923481 2 P01889 1 +Lymphocyte anergy 0.918345420359931 1.4830136863826022 0.1380707745116995 1.0 0.5551067898923481 2 P01889 1 +Positive regulation of nik nf kappab signaling 0.5960264244137488 1.483006560743476 0.1380726676739099 1.0 0.5551067898923481 13 P05067 1 +Negative regulation of neuron projection regeneration 0.9178082191780864 1.4808154966676257 0.1386557458804127 1.0 0.5564559089249868 2 Q96G23 1 +Regulation of vesicle mediated transport 0.5059387556798184 1.4798046329681318 0.1389253919232504 1.0 0.5564559089249868 141 Q9P2R3,Q4KMQ2,Q13614,O75955,Q9H270,Q9Y3E7,Q8WTV0,P05067,Q9H223,P17301,Q9H4M9,P06756,P50897,P11233,Q9NRA0,Q92673,Q06481,P04899,P51809,P0DP25,Q9NQ11,Q4J6C6,Q9P2W9,Q08722,P98194,Q9NR31,O14936,O14786,P11279,Q93009,P61978,Q08431,Q9UKS6,P31751,P51151,Q06787,Q92783,O00560,Q9H3S7,P41440,Q15833,Q07954,O14964 43 +Multivesicular body organization 0.5837291104974024 1.4783707161709103 0.1393085790964168 1.0 0.5564559089249868 14 Q9UK41,Q9H9H4,Q9BRG1,Q92783,Q9Y3E7,O14964 6 +Regulation of lipase activity 0.6059321439062053 1.477728971235951 0.1394803366524701 1.0 0.5564559089249868 12 Q07954,Q99523,P50897 3 +Response to thyroglobulin triiodothyronine 0.9167338168144068 1.4764192757037575 0.1398313712263554 1.0 0.5565022861989516 2 P16278 1 +B cell activation involved in immune response 0.5423668850273202 1.4754086393734092 0.1401027140718895 1.0 0.5571050854398023 19 P02786,Q9UQ84,P13051 3 +Regulation of lymphocyte activation 0.4527696252987923 1.475186452056393 0.1401624227888227 1.0 0.5571050854398023 57 Q9NPF0,P14174,P04439,Q9HCL2,Q08722,P10644,Q96J02,P02786,P30825,P11279,P07947,Q14254 12 +Semaphorin plexin signaling pathway 0.6451685580440802 1.4749268487603222 0.1402322111514393 1.0 0.5571050854398023 9 P42892,P51805,P13591,O14786 4 +Metal ion transport 0.4764187757345431 1.4731578807046617 0.1407084692779827 1.0 0.557875445986357 119 Q8TEL6,O15173,Q96QD8,Q4KMQ2,Q8N4V1,P55011,O43865,P06756,Q9NRA0,P33176,Q8IUH4,Q9Y666,P04899,P17612,P0DP25,P98164,Q96RD7,P02792,Q9NWR8,O00429,O00308,Q04656,O75844,P02786,P98194,O14936,Q6P4Q7,Q15043,P46934,P05556,P21796,P17252,P27105,Q9UKS6,Q9H2J7,Q9BXP2,Q06787,P08195,Q9HD20,Q92581,P05026,Q9Y6M7 42 +Positive regulation of homotypic cell cell adhesion 0.9209284288578627 1.4722992640656114 0.1409400819580792 1.0 0.5579950498563147 3 Q9Y624 1 +Regulation of carbohydrate catabolic process 0.553038439181778 1.4717016981070064 0.1411014488533966 1.0 0.5579950498563147 17 P05067 1 +Protein kinase b signaling 0.4856667364923273 1.4714117443294286 0.1411797992148549 1.0 0.5579950498563147 32 Q07021,P29317,Q14118,P00533,Q13641,P98164 6 +Response to wounding 0.4397844871731985 1.4712714423438402 0.1412177231613278 1.0 0.5579950498563147 93 O14965,P42785,Q16625,Q4KMQ2,Q14344,Q14118,Q13308,Q9Y3E7,P55011,Q8WTV0,Q9Y624,P17301,Q86YV9,O94898,Q96G23,Q04656,P00374,P10586,O14936,Q9Y6X5,P61225,P05556,Q04721,P43121,Q9UNN8,Q6YHK3 26 +Regulation of glucosylceramidase activity 0.9153908138597996 1.4709243185217284 0.1413115851707305 1.0 0.5579950498563147 2 Q14108 1 +Polyamine transport 0.9153908138597956 1.470924318521712 0.1413115851707349 1.0 0.5579950498563147 2 Q9H7F0 1 +Positive regulation of axonogenesis 0.535302162245094 1.4694855478251558 0.1417011389077158 1.0 0.5579950498563147 20 P51805,O94813,Q9Y6N7,O14786 4 +Bone cell development 0.657923012598491 1.4692037725882128 0.1417775273577342 1.0 0.5579950498563147 8 Q04721,Q15904 2 +Nuclear membrane reassembly 0.6176732389733779 1.468432217026571 0.1419868557370898 1.0 0.5579950498563147 11 Q86XL3,Q8IXJ6,Q6NUK4,Q9H6H4,Q9Y3E7,Q9NZZ3 6 +Chondroitin sulfate biosynthetic process 0.7723885265509118 1.4680648954922269 0.1420865959886468 1.0 0.5579950498563147 4 Q8N6G5 1 +Regulation of map kinase activity 0.5095527575401826 1.4677179858847422 0.1421808431079247 1.0 0.5579950498563147 25 O14641,P14174,P04062,P00533,Q92673,Q9Y6N7 6 +Regulation of animal organ morphogenesis 0.6172325777593086 1.466234044897726 0.1425845366758669 1.0 0.5579950498563147 11 O14641,Q13308,Q8TAA9,P35222,Q9Y6N7 5 +Glycoprotein catabolic process 0.7028539739539421 1.4661485857236616 0.1426078118877536 1.0 0.5579950498563147 6 P07711,P51688,O00462 3 +Anion homeostasis 0.7023890937880999 1.4641531522457396 0.1431521071662977 1.0 0.5585939702410243 6 Q9BXP2,Q9Y666,P55011 3 +Response to amine 0.6705822401677963 1.4634237148820977 0.1433514734761831 1.0 0.5585939702410243 7 P17301,P0DP25,Q7LG56 3 +Ras protein signal transduction 0.4257364940210427 1.462353403672494 0.1436443912600791 1.0 0.5585939702410243 84 Q9Y6W5,Q13501,Q14344,O75955,Q9Y624,Q9Y2I1,P11233,P62993,Q15392,O95819,P61225,O14786,P41440,Q7Z569,P05556,Q04721,Q15058,P51151,O00560,Q86VI3,Q9Y6N7 21 +Nerve growth factor signaling pathway 0.9178514365037715 1.4606428104682407 0.1441134912387107 1.0 0.5589401726168052 3 Q99523 1 +Dorsal ventral neural tube patterning 0.7699678949030659 1.4582444929602745 0.144773163913066 1.0 0.559426897502293 4 P17612,P22694 2 +Regulation of lipid catabolic process 0.5911903299172644 1.4574187767775808 0.1450008170750822 1.0 0.559426897502293 13 P01130,Q2T9J0,P31751,Q92673,Q8WTV0 5 +T cell differentiation involved in immune response 0.6691129310036825 1.45685223574566 0.1451571731955367 1.0 0.559426897502293 7 Q9NQZ7,P42345,Q04656,Q9Y2Y6 4 +Positive regulation of adaptive immune response 0.532876343118512 1.454281067429124 0.1458683972381711 1.0 0.5615221127456766 20 P02786,P04439,Q92692,P01889 4 +Regulation of macroautophagy 0.4426632254443153 1.45171545015517 0.1465807415391784 1.0 0.5623280802894595 61 Q93050,P21796,P27544,O15118,P04062,O15269,P46934,Q9Y487,Q9NQ11,Q13137,Q96KQ7 11 +Elastin metabolic process 0.9105560032232192 1.4511459097585495 0.1467392349256651 1.0 0.5623280802894595 2 P07711 1 +Regulation of hormone metabolic process 0.6992747212422898 1.4507790936698848 0.1468413829688213 1.0 0.5623280802894595 6 Q9UNE7,O75844,P16435 3 +Negative regulation of pathway restricted smad protein phosphorylation 0.909750201450451 1.4478501060673297 0.1476589760443998 1.0 0.5626598104997849 2 Q07954 1 +Substrate adhesion dependent cell spreading 0.5036189316863637 1.4468840130000442 0.1479294114192979 1.0 0.5626598104997849 26 P06756,Q14185,Q07021,Q15058,P07942,O14786,O75882 7 +Early endosome to golgi transport 0.6983635262978345 1.4468641864390328 0.1479349653661588 1.0 0.5626598104997849 6 O15260,Q9BVK6 2 +Inner ear receptor cell development 0.6528901365264862 1.4461119637632494 0.1481458006511857 1.0 0.5626598104997849 8 P54802 1 +Regulation of mitophagy 0.666648041974218 1.4458214394092936 0.1482272911315059 1.0 0.5626598104997849 7 P21796 1 +Positive regulation of calcium ion import 0.9092130002685996 1.445653009137933 0.1482745505719691 1.0 0.5626598104997849 2 Q9NRA0 1 +Commissural neuron axon guidance 0.913756045137022 1.4451276241553157 0.1484220410134611 1.0 0.5626598104997849 3 Q14118,O14786 2 +Polyol metabolic process 0.4970327131493323 1.4450967952487783 0.1484306990396329 1.0 0.5626598104997849 28 P43304,Q9NRA0,Q13510,Q9UNW1,Q13614,P04062,Q9NX62,O15269,P00374 9 +Vascular associated smooth muscle cell migration 0.7664411194661063 1.4439313869730916 0.148758276643369 1.0 0.5631060407871111 4 Q04656 1 +Regulation of monooxygenase activity 0.5992733994785986 1.4434609929046396 0.1488906531386762 1.0 0.5631060407871111 12 Q04656,P0DP25,P00533,P06280,Q8WTV0 5 +Fc receptor signaling pathway 0.652243479103423 1.4431421764423635 0.1489804243649295 1.0 0.5631060407871111 8 Q06481,Q08722 2 +Fc gamma receptor signaling pathway 0.7186659229851167 1.440575585456882 0.149704621947877 1.0 0.5649601255332297 5 Q06481,Q08722 2 +Mast cell activation involved in immune response 0.6375520049721264 1.439070268696339 0.150130614705467 1.0 0.5649601255332297 9 P51809,Q9NRA0,O00161 3 +Phospholipid homeostasis 0.9076013967230808 1.4390622497134409 0.1501328864871167 1.0 0.5649601255332297 2 Q9HCL2 1 +Cellular copper ion homeostasis 0.7183043449706339 1.4390604704169745 0.1501333905662014 1.0 0.5649601255332297 5 P05067 1 +Copper ion homeostasis 0.7183043449706339 1.4390604704169745 0.1501333905662014 1.0 0.5649601255332297 5 P05067 1 +Ear development 0.4889488079112863 1.437562300488167 0.1505582840543138 1.0 0.5653120588586708 30 P42892,O14641,P54802,Q5SZK8,Q13308,Q9Y6M7 6 +Regulation of microglial cell activation 0.9116914340681512 1.437305822310509 0.1506311152148871 1.0 0.5653120588586708 3 P53634 1 +Regulation of receptor internalization 0.5872764032251696 1.4366679997459793 0.1508123517690067 1.0 0.5653120588586708 13 Q06787,O00560,O75955,P41440 4 +Mesodermal cell differentiation 0.906258393768465 1.4335705929271036 0.1516948403981655 1.0 0.5676486992453965 2 P17301 1 +Regulation of neurotransmitter transport 0.5515860793001844 1.4332267977129134 0.1517930337895119 1.0 0.5676991698980518 16 Q4J6C6,Q06787,O75955,O14936,P41440,P0DP25,P05556,P16615 8 +Response to increased oxygen levels 0.6360812835953273 1.4321351940031557 0.1521051340453341 1.0 0.5685491401962237 9 Q15904,Q8N511 2 +Positive regulation of cell matrix adhesion 0.5861595645989693 1.4307399614594136 0.1525047557420384 1.0 0.5691315627774414 13 Q14118,O14786 2 +Protein transmembrane transport 0.4980316894442337 1.4291842820204976 0.1529512741315117 1.0 0.5697595752864756 27 Q9Y5Y5,Q3ZCQ8,Q99595,Q9NS69,O95831,P31751,Q15629,Q07820 8 +Glial cell migration 0.5858225363837476 1.4289504704162168 0.1530184697166494 1.0 0.5697595752864756 13 Q96G23,Q96N66,P30536,P07686,P07942,P35222,Q9NQC3 7 +Retina morphogenesis in camera type eye 0.7156760281742659 1.428044060864578 0.1532791768575081 1.0 0.570392583730716 5 P54802 1 +Phosphatidylglycerol metabolic process 0.5961896872941821 1.4275572670375327 0.1534193308788005 1.0 0.5705973116258165 12 Q8NCC3 1 +Regulation of lipid transport 0.5086218637964374 1.425934796854349 0.1538871640274803 1.0 0.571386023995664 23 Q07954,P06756,P14174,Q9H2C2,Q9NV96,O15260 6 +Dermatan sulfate proteoglycan metabolic process 0.908382590005372 1.4247703596864318 0.1542235929331998 1.0 0.5720013944871641 3 Q8N6G5,Q8NCH0 2 +Regulation of cellular response to insulin stimulus 0.5340003259028521 1.423946206216009 0.1544620447300946 1.0 0.5722524177894385 19 Q92673,Q06481 2 +Protein hydroxylation 0.5498514685033695 1.4231232675509886 0.1547004244286653 1.0 0.5726064545826562 16 P13674,O75718,Q96AY3,Q32P28,O00469,Q02809,O15460,Q92791,Q12797 9 +Amide transport 0.4641708999802624 1.422236544922551 0.1549575930153093 1.0 0.572722742205011 42 P16870,Q9H2D1,P07602,P98164 4 +Cobalamin metabolic process 0.6925890247783459 1.4220343754841316 0.1550162719128454 1.0 0.572722742205011 6 Q9NPF0,P33527,O14678 3 +Nik nf kappab signaling 0.5078892140022142 1.4210229553484015 0.1553100860893432 1.0 0.573169283776568 23 P05067,O43657 2 +Regulation of glial cell differentiation 0.5843242397919567 1.4209918068947682 0.1553191413172503 1.0 0.573169283776568 13 Q9Y2Y6,P01130,Q14118,P42345 4 +Olfactory behavior 0.9068580662185122 1.4189948920691722 0.1559005052443285 1.0 0.5741921149658802 3 O60266 1 +Chemosensory behavior 0.9068580662185122 1.4189948920691722 0.1559005052443285 1.0 0.5741921149658802 3 O60266 1 +Morphogenesis of a branching structure 0.5074561116820175 1.418118271263599 0.1561562377028698 1.0 0.5741921149658802 23 P29317,Q14118,O94813,Q15375 4 +Skin development 0.4566506090205024 1.4176618745918292 0.1562895060645499 1.0 0.5741921149658802 50 P17301,Q08J23,Q15392,P29317,Q13510,Q04656,O75844,P04062,P00533,Q16739,Q6YHK3 11 +Cellular response to low density lipoprotein particle stimulus 0.9065018807092944 1.4176455478012508 0.1562942751043139 1.0 0.5741921149658802 3 P01130,O15118 2 +Phosphatidylinositol dephosphorylation 0.6913814256331616 1.41683758770073 0.1565304173881263 1.0 0.5741921149658802 6 Q9NYA4 1 +Histamine production involved in inflammatory response 0.7596778445824348 1.4164679936613271 0.15663852869341 1.0 0.5741921149658802 4 P51809 1 +Histamine secretion 0.7596778445824348 1.4164679936613271 0.15663852869341 1.0 0.5741921149658802 4 P51809 1 +Histamine transport 0.7596778445824348 1.4164679936613271 0.15663852869341 1.0 0.5741921149658802 4 P51809 1 +Response to antibiotic 0.5831590519701201 1.4147988711066768 0.1571274752085085 1.0 0.5741921149658802 13 P23458,Q96KQ7 2 +Regulation of neuronal action potential 0.9011549825409696 1.4127082850454185 0.1577415145236052 1.0 0.5754946272929787 2 P04062 1 +Peroxisome fission 0.7112903225806533 1.4096503409932308 0.1586429546254415 1.0 0.5756497465618349 5 O14734,Q9Y3D6,O00429,Q9GZY8 4 +Fc receptor mediated stimulatory signaling pathway 0.6893903042579937 1.4082659070161208 0.1590523469326856 1.0 0.5757771256436683 6 Q06481,Q08722 2 +Proton transporting v type atpase complex assembly 0.8998119795863601 1.407219950496493 0.1593621775309492 1.0 0.5757771256436683 2 Q8N511 1 +Vacuolar proton transporting v type atpase complex assembly 0.8998119795863601 1.407219950496493 0.1593621775309492 1.0 0.5757771256436683 2 Q8N511 1 +Dendritic transport 0.6891214804885024 1.4071083442392696 0.1593952641947784 1.0 0.5757771256436683 6 P33176,Q14254 2 +Forebrain neuron differentiation 0.6574826003520194 1.4047347301396849 0.1601001742415069 1.0 0.5757771256436683 7 P51805,O14786 2 +Forebrain neuron development 0.6574826003520194 1.4047347301396849 0.1601001742415069 1.0 0.5757771256436683 7 P51805,O14786 2 +Forebrain generation of neurons 0.6574826003520194 1.4047347301396849 0.1601001742415069 1.0 0.5757771256436683 7 P51805,O14786 2 +Detection of mechanical stimulus 0.7567478685393468 1.4045648972448288 0.1601507010007101 1.0 0.5757771256436683 4 P17301,P19022 2 +Regulation of body fluid levels 0.4395538833357127 1.403052669672277 0.1606011335068564 1.0 0.5757771256436683 60 P17301,Q99808,P61225,Q86YV9,Q4KMQ2,P22694,Q04656,Q14344,P04062,Q9UNN8,P04899,Q16739,P17612,Q9Y6X5,P19021,Q9Y624 16 +Metal ion export 0.6043889504669088 1.4019908676454798 0.1609179737892834 1.0 0.5757771256436683 11 Q04656,P05026,Q4KMQ2,P0DP25 4 +Positive regulation of cold induced thermogenesis 0.5695463776084624 1.400865896928973 0.1612541784982688 1.0 0.5757771256436683 14 Q06481,P23786 2 +Pyramidal neuron differentiation 0.6876618458392973 1.4008219328589278 0.1612673282058463 1.0 0.5757771256436683 6 P04062,P51805 2 +Dendritic cell migration 0.7089114703046818 1.3996677776060444 0.1616128272393964 1.0 0.5757771256436683 5 Q07021 1 +Cell activation 0.5106129772929142 1.3993935344230473 0.1616950046836625 1.0 0.5757771256436683 151 P07711,P14174,P15260,Q14344,P04062,P46379,P05067,P07947,Q9Y624,Q9NQZ7,Q8IWT6,Q9NRA0,P53634,Q9Y2Y6,P10644,P24390,Q96J02,P51809,Q5ZPR3,P01130,Q9NPF0,P04439,Q9BY67,Q08722,P13051,Q04656,P02786,O43164,P61225,P11279,P12956,Q9UQ84,Q14254,Q96L92,P05556,Q04721,P17252,Q6PHR2,Q92542,O00161,P30825,P78310,Q15833,Q07954,Q9HCL2,Q92692 46 +Regulation of transmission of nerve impulse 0.9013970983342277 1.3983082084378815 0.1620205339866287 1.0 0.5757771256436683 3 P17301,P04062 2 +Signal release 0.4388738535093182 1.3965649896023278 0.1625444245597493 1.0 0.5757771256436683 60 Q4J6C6,Q8IWT6,P14174,P50897,Q15833,O00161,Q06787,O14936,Q7L0J3,O95721,P51809,Q5SQN1,P16870,P0DP25,P56545 15 +Cell cell adhesion mediated by integrin 0.7545975333104967 1.3958272917002137 0.1627665097906934 1.0 0.5757771256436683 4 O00592 1 +Modulation of excitatory postsynaptic potential 0.7077218143695151 1.3946741207298026 0.1631141323270957 1.0 0.5757771256436683 5 P05067,Q9UQB8 2 +Positive regulation of actin cytoskeleton reorganization 0.7076772760147269 1.394487150297335 0.1631705471286773 1.0 0.5757771256436683 5 Q9UQB8,O14786 2 +Respiratory gaseous exchange by respiratory system 0.6156492747862736 1.3943990630889285 0.1631971308802797 1.0 0.5757771256436683 10 Q7KZN9,P10253 2 +Actin cytoskeleton reorganization 0.4930789543904015 1.3941789372698217 0.1632635767102743 1.0 0.5757771256436683 27 Q04721,P11233,Q9UQB8,P98194,Q13308,P78310,O14786,Q9Y624 8 +Magnesium ion homeostasis 0.9001046993654318 1.3934129594739768 0.1634949490515203 1.0 0.5757771256436683 3 Q8NE01 1 +Extracellular exosome assembly 0.7539537813419178 1.3932112131442007 0.163555929938024 1.0 0.5757771256436683 4 O00560 1 +Dopamine receptor signaling pathway 0.6413751223660984 1.3931376738079468 0.1635781625803232 1.0 0.5757771256436683 8 Q92542,P08754,P09471 3 +Protein transmembrane import into intracellular organelle 0.5790881482905829 1.3931371926936222 0.1635783080398114 1.0 0.5757771256436683 13 O95831,Q9Y5Y5,Q99595,Q3ZCQ8 4 +Cellular response to copper ion 0.8996336509404714 1.3916288166718696 0.1640348279843793 1.0 0.5757771256436683 3 P05067 1 +Isoprenoid metabolic process 0.4861746338218754 1.3912113111203033 0.1641613582582175 1.0 0.5757771256436683 29 Q9HB40,P61916,P98164 3 +Modulation by host of viral genome replication 0.6274108347902534 1.3911788352172196 0.1641712035677516 1.0 0.5757771256436683 9 P27105 1 +Positive regulation of syncytium formation by plasma membrane fusion 0.6849469444341136 1.3891240791733297 0.1647950228289376 1.0 0.5757771256436683 6 Q9H4M9,O75955,P41440 3 +Regulation of syncytium formation by plasma membrane fusion 0.6849469444341136 1.3891240791733297 0.1647950228289376 1.0 0.5757771256436683 6 Q9H4M9,O75955,P41440 3 +Positive regulation of protein exit from endoplasmic reticulum 0.7063655024167472 1.3889798037773722 0.1648388914790777 1.0 0.5757771256436683 5 Q92673,Q9NV96,Q92544 3 +Protein retention in er lumen 0.7528144944157409 1.38858108543462 0.1649601722588722 1.0 0.5757771256436683 4 P24390 1 +Maintenance of protein localization in endoplasmic reticulum 0.7528144944157409 1.38858108543462 0.1649601722588722 1.0 0.5757771256436683 4 P24390 1 +Cellular response to starvation 0.4616458884971578 1.3882896217813958 0.1650488711683122 1.0 0.5757771256436683 38 Q96QD8,P04062,P13473,P11166,Q96KQ7 5 +Fatty acid derivative biosynthetic process 0.5335962139091074 1.3873210793126312 0.1653438781934175 1.0 0.5759535715448464 18 Q9UMR5,P19021,P50897 3 +Heparan sulfate proteoglycan metabolic process 0.6263148123450896 1.3859931278937565 0.1657490019129845 1.0 0.5770265991254665 9 Q99805,Q7LGA3,P51688 3 +Glycosylceramide biosynthetic process 0.8975702772710379 1.383813988939628 0.1664154185116571 1.0 0.5781835846890232 3 Q16739 1 +Negative regulation of cell volume 0.8933655654042565 1.3808877583009609 0.1673134744924751 1.0 0.5802933247419756 2 P51790 1 +Alpha beta t cell differentiation 0.5766972387155275 1.38039712306751 0.167464405499947 1.0 0.5802933247419756 13 Q9NQZ7,P07711,Q04656 3 +Homologous chromosome pairing at meiosis 0.6127351695534212 1.380201457137975 0.1675246254893776 1.0 0.5802933247419756 10 Q92791,Q96KQ7,Q9BTX1 3 +Positive regulation of mitochondrial translation 0.6384080571630757 1.3794576790896251 0.1677536860711717 1.0 0.5802933247419756 8 Q07021,Q9Y2R0 2 +Lipid storage 0.5209667266136689 1.379319967830989 0.1677961226648887 1.0 0.5802933247419756 20 Q9H4M9,P06756,P04062,P07686,Q8WTV0,P17900,P35610 7 +Regulation of fc receptor mediated stimulatory signaling pathway 0.8962825961472233 1.3789373894689247 0.1679140589116934 1.0 0.5803816517927639 3 Q06481 1 +Regulation of lamellipodium assembly 0.532077612749044 1.3781039027743416 0.1681712107770814 1.0 0.5807551192949159 18 Q9Y6W5,P29317,Q16625,O94813,Q04656,Q12792,P47756 7 +Positive regulation of myoblast fusion 0.7035878738077138 1.3773146965004142 0.1684149734103566 1.0 0.5807551192949159 5 O75955,P41440 2 +Regulation of myoblast fusion 0.7035878738077138 1.3773146965004142 0.1684149734103566 1.0 0.5807551192949159 5 O75955,P41440 2 +Interleukin 12 production 0.624258292043109 1.376257977139771 0.168741778136731 1.0 0.5807551192949159 9 Q08722,P01889 2 +Neuromuscular junction development 0.5992250370593353 1.376069625984726 0.1688000782077121 1.0 0.5807551192949159 11 P05067 1 +Calcium ion import 0.5649307764700925 1.3755318553678362 0.1689666167762851 1.0 0.5807551192949159 14 P21796,Q9NWR8,Q9NRA0,O75844,O14936,P16615 6 +Response to estradiol 0.5203625885610605 1.3755038166239018 0.1689753032863452 1.0 0.5807551192949159 20 P17301,O95831,P00533,P19021 4 +Branching involved in blood vessel morphogenesis 0.7491578719846811 1.3737180333746395 0.1695292361867828 1.0 0.5816870012068969 4 Q14344,O14786 2 +Response to zinc ion 0.6235822997769419 1.3730565707069715 0.1697347608143422 1.0 0.5816870012068969 9 Q9NQ11,P19021 2 +Positive regulation of interferon gamma production 0.7023655386106147 1.372179842632303 0.1700074588771916 1.0 0.5816870012068969 5 P04439 1 +Positive regulation of translational initiation 0.5984457053470402 1.3721532553367926 0.1700157337340051 1.0 0.5816870012068969 11 O15514,Q13217,Q07666,Q9P2X3,O00571 5 +Regulation of triglyceride catabolic process 0.8912167606768864 1.3721151974921328 0.1700275791352299 1.0 0.5816870012068969 2 Q92673 1 +Triglyceride catabolic process 0.8912167606768864 1.3721151974921328 0.1700275791352299 1.0 0.5816870012068969 2 Q92673 1 +Amyloid beta clearance by cellular catabolic process 0.8942340557258686 1.3711799848960489 0.1703188559303894 1.0 0.5820119623031742 3 P01130 1 +Response to forskolin 0.8909481600859604 1.371018813134374 0.1703690914584332 1.0 0.5820119623031742 2 O60266 1 +Insulin like growth factor receptor signaling pathway 0.7481517131099037 1.3696277451589434 0.1708031341219069 1.0 0.5820119623031742 4 P11717 1 +Organelle disassembly 0.4360518025180521 1.3695981273414113 0.1708123845050699 1.0 0.5820119623031742 60 P21796,Q7Z3C6,P53365,Q13501,P27544,P33176,Q5MNZ6,Q13190,O00429,Q9Y6I9,P04062,P60520,Q8TDY2,Q9Y3D6,Q9NQ11 15 +Endothelial cell chemotaxis 0.6803505287893495 1.3693044123587266 0.1709041393334298 1.0 0.5820119623031742 6 Q99538 1 +Negative regulation of natural killer cell mediated immunity 0.8927970602962116 1.3657389084520457 0.1720209273854824 1.0 0.5849235186897531 3 P04439 1 +Enzyme linked receptor protein signaling pathway 0.498553366720973 1.3647976204897274 0.1723166669071034 1.0 0.5853351756773479 144 Q99523,O14964,P00533,P07947,Q99538,Q9UIQ6,O95470,Q9NYA4,Q92673,O94898,Q06481,P04899,P67870,P11717,P98164,Q92896,O14654,P29317,Q8WWQ0,P10586,Q9H3E2,O00459,O14786,Q15043,P46934,P05556,Q04721,Q92859,Q9UQB8,P31751,Q9BRG1,Q15375,O00560,Q6YHK3,Q07954,Q9Y6N7 36 +Retrograde trans synaptic signaling 0.8914562063406757 1.360662297905804 0.173620434375274 1.0 0.5864940278140567 3 Q14118,Q9Y4F1 2 +Positive regulation of triglyceride metabolic process 0.8914562063406751 1.3606622979058032 0.1736204343752743 1.0 0.5864940278140567 3 P01130,Q8WTV0 2 +Positive regulation of cholesterol storage 0.8882621541767486 1.3600573527177997 0.1738117753584773 1.0 0.586844593678849 2 Q8WTV0 1 +Cellular response to external stimulus 0.4220509239244961 1.3563708336393463 0.1749812083841424 1.0 0.5884215045612256 66 P17301,Q9H773,O95831,Q96QD8,P04062,Q14118,P13473,P11166,Q96KQ7,Q9Y624 10 +Cell maturation 0.4840759057238567 1.352140406895758 0.1763304032241699 1.0 0.5905878872605631 28 P05067,O75503 2 +Branched chain amino acid transport 0.8887295023167023 1.3503401371789714 0.1769069032576644 1.0 0.5919271421032787 3 Q9H2J7 1 +Response to iron ion 0.6442732597326946 1.3453415721871074 0.1785149542508048 1.0 0.5943403991002952 7 P02786 1 +Protein import into mitochondrial matrix 0.6306726804884807 1.3437387786173995 0.1790328727844974 1.0 0.5944146899597942 8 Q99595,O14925,Q3ZCQ8 3 +Synaptonemal complex organization 0.6435261845134691 1.3419767321903078 0.1796035401147642 1.0 0.5944146899597942 7 Q92791,Q96KQ7 2 +Negative regulation of receptor mediated endocytosis 0.5923950759578261 1.3417093140245782 0.1796902658696721 1.0 0.5944146899597942 11 P05067,O00560 2 +Neurotransmitter uptake 0.6738718414272205 1.3413389651763032 0.1798104242294957 1.0 0.5945187287548499 6 O75955,P05556,P41440 3 +Regulation of protein autophosphorylation 0.5920335855801921 1.3398883884456878 0.1802816336871759 1.0 0.594819533996966 11 Q9P2X3,P22413,Q15375,P61225,P0DP25 5 +Extracellular matrix disassembly 0.6040489771558978 1.3377983792421009 0.1809621703772215 1.0 0.5954842344859756 10 Q07954,P41440 2 +Lamellipodium organization 0.4718462682175789 1.3377101045880586 0.1809909557815476 1.0 0.5954842344859756 31 P53365,P29317,Q16625,O94813,Q04656,P05556 6 +Vesicle mediated transport in synapse 0.455023041538949 1.3362741859712006 0.1814596707269045 1.0 0.5964407617516989 39 Q4J6C6,P19022,P51790,O00161,Q06787,O14936,Q7L0J3,O95721,Q5SQN1,P0DP25,P54920,P56545 12 +Negative regulation of inflammatory response 0.5196561531018081 1.3351540273065643 0.1818259397942996 1.0 0.5973516904418608 19 Q92485,P01130 2 +Regulation of receptor localization to synapse 0.69330894633017 1.3341094981434134 0.1821679734747698 1.0 0.5981821451386122 5 Q14118 1 +Sulfur compound transport 0.577085453275822 1.3285780171617825 0.1839872285535773 1.0 0.6010011469643332 12 Q70HW3,Q8IWT6,Q9UBX3,Q8TB61,P33527,Q9H0H5 6 +Microvillus assembly 0.6404076405017923 1.3279245783435738 0.1842030241858516 1.0 0.6011017337863455 7 O00592,O95819 2 +Negative regulation of bmp signaling pathway 0.6400899584643294 1.3264925557589031 0.1846765993023478 1.0 0.6011017337863455 7 Q92673 1 +Coronary vasculature development 0.6017285797159798 1.3264506415282382 0.1846904740517683 1.0 0.6011017337863455 10 P98164 1 +Positive regulation of focal adhesion assembly 0.6267838572215559 1.3257537818787328 0.1849212665778739 1.0 0.6011017337863455 8 O95819,O14786 2 +Basement membrane assembly 0.6702155170058808 1.3255423860351574 0.1849913208066786 1.0 0.6011017337863455 6 Q14118 1 +Negative regulation of metallopeptidase activity 0.8820966823249734 1.3252404508241489 0.1850914128209351 1.0 0.6011017337863455 3 Q92673 1 +Postsynaptic actin cytoskeleton organization 0.691179944427647 1.325154355239385 0.1851199609870213 1.0 0.6011017337863455 5 Q9Y4F1 1 +Cellular response to estrogen stimulus 0.6698346370668279 1.3238963140638964 0.1855374825470197 1.0 0.6019493416598384 6 Q969T9,Q13772,Q8IZL8 3 +Purine containing compound transmembrane transport 0.6011922592332368 1.323826630443249 0.1855606296432745 1.0 0.6019493416598384 10 Q8TB61,Q99808,P41440 3 +Regulation of camp mediated signaling 0.881588689271268 1.3233187497360546 0.185729398980492 1.0 0.6021032673756129 3 O60291 1 +Regulation of electron transfer activity 0.7367199354474492 1.3231432069888218 0.1857877584202876 1.0 0.6021032673756129 4 Q9NRA0 1 +Response to acid chemical 0.493118636229149 1.3215216109826904 0.1863275015613319 1.0 0.603269041286979 23 O95831,Q9UQB8,Q04656,P00533,Q14103,Q99729 6 +Long chain fatty acid transport 0.5546693886437727 1.3190253665109095 0.1871606322073864 1.0 0.6045062925560982 14 P31751,P14174,P23786,P11166 4 +Regulation of adaptive immune response 0.4875818057834581 1.3162196688584118 0.1881003239083305 1.0 0.6069563653508094 25 P02786,P04439,Q92692,P01889 4 +Camp metabolic process 0.8792566234978154 1.3144980032885971 0.1886786695925679 1.0 0.6080434041680198 3 O60266 1 +Positive regulation of cytoplasmic transport 0.6239539811326114 1.3126551242830962 0.189299185574113 1.0 0.6090653584818558 8 Q92673,Q9H270,Q13614 3 +Endocytic recycling 0.4683128603751792 1.3110542136796122 0.1898394481438283 1.0 0.6095832778231038 31 Q9H4M9,O43752,Q15904,Q92673,Q9H3S7,Q9H223,Q96L92 7 +Cardiac conduction system development 0.878251142066466 1.3106955794375732 0.1899606327675642 1.0 0.6095832778231038 3 Q04721 1 +Protein localization to cell junction 0.4866366760174219 1.309655621628027 0.1903123628432863 1.0 0.6095832778231038 25 Q9Y2Q5,P33176,Q9UQB8,P23458,Q14168,Q14118,Q12959,Q9BQT9,Q9Y624 9 +Morphogenesis of an epithelial sheet 0.6101958362288098 1.3095251088017996 0.1903565381823098 1.0 0.6095832778231038 9 Q04721,Q14118 2 +Positive regulation of interleukin 1 production 0.5982262767498765 1.3093074157674565 0.1904302386500664 1.0 0.6095832778231038 10 P05067 1 +Regulation of lipoprotein particle clearance 0.6362593509725638 1.309217558860588 0.1904606660342553 1.0 0.6095832778231038 7 P01130,P61978 2 +Export across plasma membrane 0.5852858645978803 1.3058570352152006 0.1916011798750356 1.0 0.6117728001536393 11 P33527,Q4KMQ2,Q12959,P0DP25,P05026 5 +Maintenance of blood brain barrier 0.6224227891692853 1.305563946730104 0.1917008876110721 1.0 0.6117996898901932 8 Q16625,Q9Y624,P05556 3 +Dendritic cell chemotaxis 0.7320798456393489 1.3042725780014308 0.1921406615524548 1.0 0.6120427542458734 4 Q07021 1 +B cell mediated immunity 0.5090599126237932 1.3038762906663066 0.1922757653195976 1.0 0.6120427542458734 20 P02786,Q9UQ84,P13051,Q92692 4 +Manganese ion transport 0.8764105319720565 1.30373608456752 0.192323581631514 1.0 0.6120427542458734 3 Q9HD20,Q15043 2 +Manganese ion transmembrane transport 0.8764105319720565 1.30373608456752 0.192323581631514 1.0 0.6120427542458734 3 Q9HD20,Q15043 2 +Regulation of epithelial cell migration 0.4413648642222461 1.3031447774714346 0.1925253389703756 1.0 0.6120427542458734 52 Q99538,P17301,P42785,P29317,O94813,Q13685,O14786,Q8WTV0 8 +Postsynaptic cytoskeleton organization 0.6648108984468181 1.3021760082748266 0.1928562246779304 1.0 0.6120427542458734 6 Q9Y4F1 1 +Tissue remodeling 0.4967375485635913 1.3021271656084246 0.1928729180792725 1.0 0.6120427542458734 22 Q04721,O14773,P29317,Q04656,P02786,P38571 6 +Positive regulation of mast cell activation involved in immune response 0.8752112930749323 1.29920248756909 0.1938744480494163 1.0 0.6135600215715511 3 Q9NRA0 1 +Cellular lipid catabolic process 0.4063080746703149 1.2990580888576064 0.193923994825673 1.0 0.6135600215715511 81 Q92485,P01130,Q8WTV0,Q2T9J0,P50897,P06865,Q92484,Q8NHP8,Q13510,P23786,P07686,Q92673,P04062,P06280,Q8NCC3,P17900,P04066,Q99519 18 +Neuron projection organization 0.4849956668693704 1.2982497890310287 0.1942015141871009 1.0 0.6135600215715511 25 Q99538,P05067,Q9UQB8,Q05086 4 +Plasma membrane raft organization 0.8747423521568725 1.2974298884600424 0.194483314193175 1.0 0.6135600215715511 3 P41440 1 +Plasma membrane raft assembly 0.8747423521568725 1.2974298884600424 0.194483314193175 1.0 0.6135600215715511 3 P41440 1 +Positive chemotaxis 0.6205528433603045 1.2969004910718471 0.1946654275343251 1.0 0.6135600215715511 8 P14174,O14786 2 +Tetrapyrrole metabolic process 0.489283913145628 1.2955456767918885 0.1951320549988777 1.0 0.6135600215715511 23 Q9NPF0,P30519,P33527,P30536,O14678,P22830,Q7KZN9,Q9H3L0 8 +Glycosylation 0.433373608960873 1.2946543963778614 0.1954394783260644 1.0 0.6135600215715511 57 P33908,Q86SF2,Q9BXS4,Q2TAA5,O43505,Q16706,Q10471,Q86YN1,Q10472,O60512,O15118,P04062,O94766,Q9H9S5,Q9Y673,Q10469,O75503,Q9Y2G5 18 +Regulation of lamellipodium organization 0.5015672491229913 1.2933811804969524 0.195879255793467 1.0 0.6140237475808306 21 P29317,Q16625,O94813,Q04656 4 +Glycosylceramide catabolic process 0.8734031415202721 1.2923682489900832 0.1962296469252376 1.0 0.6142784840332199 3 P06280 1 +Negative regulation of t cell proliferation 0.6624845050165497 1.292112498352924 0.1963181882114115 1.0 0.6142784840332199 6 Q96J02,P10644 2 +Response to oxygen levels 0.4059684127478578 1.2909726568254287 0.1967131591106667 1.0 0.6142784840332199 70 P17301,Q99808,P30519,O95831,Q15904,O75306,Q04656,Q8N511,P02786,Q9Y487,Q92544,P11166,P05026,P19021 14 +Negative regulation of map kinase activity 0.60596566632721 1.289398969022173 0.1972594196625716 1.0 0.6146293388945215 9 Q92673 1 +Positive regulation of glucose transmembrane transport 0.6617932798009902 1.2891217989129156 0.1973557462057749 1.0 0.6146293388945215 6 Q16625 1 +Positive regulation of glucose import 0.6825255023460512 1.288734026752799 0.1974905686952199 1.0 0.6146293388945215 5 Q16625 1 +Positive regulation of protein phosphorylation 0.4694589325299438 1.288689424883551 0.1975060804089157 1.0 0.6146293388945215 127 P14174,Q8NDZ4,Q13501,O75955,Q14118,P00533,P05067,Q9H223,P07947,P98155,P67870,Q14012,P0DP25,O14641,P02786,P14635,Q6PJG6,P51116,O14786,P61225,P12956,O00571,Q15058,P31751,P51114,Q12959,Q15375,Q06787,O00560,P41440,Q8TDY2,Q9Y6N7 32 +Regulation of receptor binding 0.7278694937731207 1.2871502067812106 0.1980419387446288 1.0 0.6146293388945215 4 P10586 1 +Response to l glutamate 0.6819807517483985 1.2864407767253987 0.1982892751194849 1.0 0.6146293388945215 5 O95831 1 +Mitochondrion endoplasmic reticulum membrane tethering 0.7275552485081047 1.2858723132205396 0.1984876277567138 1.0 0.6146293388945215 4 Q8NEN9,O43865 2 +Cell part morphogenesis 0.4983409846834606 1.2855911004863865 0.1985858042766699 1.0 0.6146293388945215 150 O14965,Q9P265,Q9Y6W5,Q13740,O75955,Q14118,P05067,P51805,Q9ULH0,P98155,P35613,O15031,P33176,Q06481,Q9P2X3,Q13641,P98164,Q8N0X7,P13591,Q9BVA1,O14641,Q9NUM4,P29317,Q04656,Q9Y4F1,Q92692,O95819,O14786,P46934,P05556,P42892,Q04721,Q92859,Q9UQB8,O94813,Q15375,P41440,Q92581,Q05086,Q9Y6N7 40 +Pyrimidine containing compound catabolic process 0.6046563616744479 1.2831651179823185 0.199434233884534 1.0 0.6159484956194228 9 Q9H773 1 +Osteoclast development 0.7268114240165071 1.2828475585069197 0.1995454884705667 1.0 0.6159797139512586 4 Q15904 1 +Dicarboxylic acid transport 0.510959849378335 1.2809969055957835 0.200194752991109 1.0 0.6166103659123544 19 Q8IWT6,P05556,Q9H2D1,Q9UBX3,P55011,P41440,P98164 7 +Polysaccharide biosynthetic process 0.5210294195281006 1.2809803718630437 0.2002005604633367 1.0 0.6166103659123544 17 P31751,Q7LGA3,O43505,Q8N6G5 4 +Branching morphogenesis of an epithelial tube 0.5160511089368273 1.280394906711348 0.2004062843480389 1.0 0.6169604582914824 18 P29317,O94813,Q14118 3 +Decidualization 0.8700251733234446 1.2796050264612864 0.2006840811889629 1.0 0.617532007405156 3 P07858 1 +Regulation of nitric oxide metabolic process 0.5671327782279648 1.2767282712668993 0.2016981967509195 1.0 0.6181665658267209 12 P06280 1 +Negative regulation of transmembrane transport 0.4861692289355401 1.2744055372971097 0.2025197309205224 1.0 0.6181665658267209 23 P21796,P31751,Q04656,Q06787,Q06481,P0DP25,P46934 7 +Cell differentiation in hindbrain 0.7245002514280683 1.2734496572825604 0.2028585259551412 1.0 0.6181665658267209 4 Q04656 1 +Regulation of protein exit from endoplasmic reticulum 0.6026109076021553 1.273422218895453 0.2028682571055795 1.0 0.6181665658267209 9 Q9NR31,Q92673,Q9NV96,Q92544 4 +Regulation of systemic arterial blood pressure 0.602600069168626 1.2733705802180793 0.2028865719225989 1.0 0.6181665658267209 9 P42892,P42785 2 +Artery morphogenesis 0.5908362108755002 1.2730761487896232 0.2029910216540646 1.0 0.6181665658267209 10 P98164,P01130,Q07954 3 +Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.5352619824405378 1.271361774549187 0.2035999749643198 1.0 0.6181665658267209 15 Q9UK41,Q9H9H4,Q9BRG1,Q92783,Q9Y3E7,Q9H3S7,P46934 7 +Vesicle fusion to plasma membrane 0.8678130037614171 1.2712499746657648 0.2036397329155583 1.0 0.6181665658267209 3 O95721,Q5SQN1 2 +Tissue migration 0.4090339988750663 1.2710909112854127 0.2036963083144303 1.0 0.6181665658267209 68 Q99538,P17301,P42785,P29317,O94813,Q13685,O95819,O14786,Q8WTV0,Q9Y6N7 10 +T cell mediated immune response to tumor cell 0.7237337919999749 1.2703331890810212 0.2039659707500409 1.0 0.6181665658267209 4 P04439 1 +Developmental growth involved in morphogenesis 0.4388423556664166 1.2698827674476514 0.2041263923936336 1.0 0.6181665658267209 51 O14965,Q9P265,Q92581,O94813,Q13740,Q15375,Q13308,Q9P2X3,P05067,O14786,P51805,P05556 12 +Cellular response to epinephrine stimulus 0.7235194118749221 1.269461525124196 0.2042765046260757 1.0 0.6181665658267209 4 P17252,P17612 2 +Response to epinephrine 0.7235194118749221 1.269461525124196 0.2042765046260757 1.0 0.6181665658267209 4 P17252,P17612 2 +3 phosphoadenosine 5 phosphosulfate biosynthetic process 0.8656997045393586 1.2681948795001283 0.2047283651825986 1.0 0.6181665658267209 2 Q8TB61 1 +Regulation of immune response 0.4828351726817598 1.2669489322671017 0.2051735505572449 1.0 0.6181665658267209 139 Q92485,P01889,Q9NUD5,Q5KU26,O75955,O00115,O15400,P07947,Q9NQZ7,O43405,Q9NRA0,Q07021,Q96J02,Q07666,Q06481,P51809,Q7KYR7,Q6AZY7,Q5ZPR3,Q9UBC1,P04439,Q9BY67,Q6PIJ6,Q08722,P02786,O43164,O43657,P11279,Q14254,Q9NPR9,P41440,Q15833,Q92692 33 +Organic hydroxy compound metabolic process 0.4738641896820948 1.2666739683350816 0.2052718917466491 1.0 0.6181665658267209 132 Q9BQE5,P43304,P07858,Q9NX62,Q9NWW5,P04062,Q8WTV0,P05067,P98155,Q99538,Q9BXW6,Q9NRA0,P61916,O75845,P56937,Q13510,O15269,Q16850,P38571,P98164,P01130,Q15392,P21964,Q04656,Q15800,Q9H2C2,P48735,P34913,O15118 29 +Myeloid cell differentiation 0.4062924099577444 1.2664355587618157 0.2053571869529629 1.0 0.6181665658267209 83 P29317,Q15904,P02786,O00115,P04062,Q6YHK3,P05067,Q86WC4 8 +Reactive oxygen species biosynthetic process 0.5774016542013619 1.2659997454806018 0.2055131733770505 1.0 0.6181665658267209 11 P51790 1 +Regulation of necrotic cell death 0.5552215052019454 1.2654106709284554 0.2057241519479848 1.0 0.6181665658267209 13 Q13510 1 +Monovalent inorganic anion homeostasis 0.722338073390783 1.2646583853763282 0.2059938137148145 1.0 0.6181665658267209 4 Q9BXP2,P55011 2 +Tolerance induction 0.865960682934978 1.2642562003778033 0.206138084892463 1.0 0.6181665658267209 3 P01889 1 +Regulation of tolerance induction 0.865960682934978 1.2642562003778033 0.206138084892463 1.0 0.6181665658267209 3 P01889 1 +Forebrain development 0.3927225084126774 1.264188906613834 0.2061622315722391 1.0 0.6181665658267209 74 P62995,Q9Y6N7,Q7Z4L5,Q96QD8,Q04656,O94813,P00533,P07942,P11166,P05067,O14786,P51805,P98164 13 +Cranial nerve development 0.721980495345523 1.2632045817028257 0.2065156667081775 1.0 0.6181665658267209 4 O14786 1 +Natural killer cell degranulation 0.8645147373242486 1.2587982174613743 0.208103224371174 1.0 0.6195863212695428 3 P11279 1 +Natural killer cell activation involved in immune response 0.8645147373242486 1.2587982174613743 0.208103224371174 1.0 0.6195863212695428 3 P11279 1 +Negative regulation of platelet derived growth factor receptor signaling pathway 0.8632822992210722 1.2583803078212883 0.2082542501318398 1.0 0.6195863212695428 2 Q07954 1 +Insulin receptor signaling pathway 0.4536730594458716 1.256175843909404 0.2090522227784108 1.0 0.6210407788390556 33 O14654,P62993,Q9UQB8,Q8WWQ0,P31751,Q92673,O00459,P04899,Q15043 9 +Maternal placenta development 0.6536166830083852 1.2537258562443845 0.2099416665058124 1.0 0.6220609688295116 6 P07858 1 +Forebrain regionalization 0.8619392962664503 1.252930530130285 0.2102309899132861 1.0 0.6220609688295116 2 Q7Z4L5 1 +Myeloid cell apoptotic process 0.6237089668642833 1.252528676319575 0.2103772858142067 1.0 0.6220875832167915 7 P07711 1 +Cell junction assembly 0.4151618497295887 1.252028873016348 0.2105593432495323 1.0 0.6222084296553639 90 P19022,Q16625,O75955,Q5T2T1,P05067,Q9Y624,P17301,O15031,Q9BQT9,P17612,O60716,Q13641,P29317,Q9Y4F1,O95819,O14786,P17252,O00192,Q12959,Q15375,O15228,O00560,P41440 23 +Developmental maturation 0.4356235177068388 1.2512999090992398 0.2108250786345133 1.0 0.6223453811821809 52 Q08J23,P51790,O75787,P04062,Q14118,P05067,O75503 7 +Positive regulation of peptidyl tyrosine phosphorylation 0.5058654930253011 1.2491642627828976 0.2116050000959424 1.0 0.623737250784187 19 P07947,P14174,Q9H223,O14786 4 +Organic cation transport 0.6227610896269069 1.2482422311886687 0.2119423626761625 1.0 0.623737250784187 7 Q9H7F0,Q96QD8 2 +Dna catabolic process 0.5967468756762633 1.2454642649410783 0.2129611432629432 1.0 0.6259936763808094 9 O00115 1 +Mitochondrion distribution 0.6716535359689753 1.2429545997862033 0.2138845638957289 1.0 0.6276735407374443 5 Q9BUK6 1 +Cellular response to manganese ion 0.8600606592300478 1.2419940023515863 0.2142387749352969 1.0 0.6278217182406474 3 P05067 1 +Somatic diversification of immunoglobulins involved in immune response 0.5186535675443033 1.239938375288567 0.2149981884332019 1.0 0.628732233302689 16 P02786,P13051 2 +Immunoglobulin production involved in immunoglobulin mediated immune response 0.5186535675443033 1.239938375288567 0.2149981884332019 1.0 0.628732233302689 16 P02786,P13051 2 +Regulation of phosphatidylinositol dephosphorylation 0.8587160891754092 1.2398594673548615 0.2150273781288048 1.0 0.628732233302689 2 Q9NYA4 1 +Negative regulation of myelination 0.8589468027941937 1.2377938000663828 0.2157925279225987 1.0 0.628732233302689 3 Q9Y2Y6,P53634 2 +Negative regulation of nervous system process 0.8589468027941937 1.2377938000663828 0.2157925279225987 1.0 0.628732233302689 3 Q9Y2Y6,P53634 2 +Multicellular organismal homeostasis 0.4007382832053635 1.2375933345183217 0.2158668871941715 1.0 0.628732233302689 81 O14773,P42785,Q13501,Q16625,P23786,P22694,P04062,Q9Y624,Q9UIQ6,P51790,Q06481,P38571,P11166,Q9H9B1,P02786,Q16739,P05556,O43847,P78310 19 +Central nervous system neuron differentiation 0.4807548201643204 1.2375703279239958 0.2158754222776553 1.0 0.628732233302689 23 P51805,O94813,Q04656,O14786 4 +Lipoprotein biosynthetic process 0.498647062630444 1.2375167681030714 0.2158952930675353 1.0 0.628732233302689 20 P04062,Q8IUH4,Q8TDY2,Q16739 4 +Cell morphogenesis involved in differentiation 0.4899792561393518 1.2371302915559814 0.2160387156045748 1.0 0.628732233302689 147 O75955,Q14118,P05067,P51805,Q9ULH0,P98155,Q14517,P35613,P06756,Q07021,Q06481,Q13641,P13591,Q9NUM4,P29317,Q9Y4F1,O14786,P46934,P05556,P42892,Q04721,Q92859,O94813,Q15375,P41440,O75882,Q92581,Q05086,Q9Y6N7 29 +Regulation of smoothened signaling pathway 0.5135865239006202 1.2362105084228077 0.2163803256076029 1.0 0.628732233302689 17 Q7Z4L5,P22413,Q8WWQ0,O60291,P22694,P17612,Q6PHR2 7 +Regulation of homotypic cell cell adhesion 0.6494351113017127 1.2356128259565455 0.2166025148474961 1.0 0.628732233302689 6 P23458,Q9Y624 2 +Planar cell polarity pathway involved in neural tube closure 0.8573730862207869 1.2344168194474756 0.2170476247614767 1.0 0.628732233302689 2 O14641 1 +Cochlea morphogenesis 0.8573730862207869 1.2344168194474756 0.2170476247614767 1.0 0.628732233302689 2 O14641 1 +Prostate gland growth 0.858051037554027 1.234416637509228 0.2170476925222626 1.0 0.628732233302689 3 P07602 1 +Fibroblast proliferation 0.5085084225423007 1.23414990261402 0.2171470512006492 1.0 0.628732233302689 18 P14174,O75844,P00533,P50402,Q13049 5 +Trans synaptic signaling by trans synaptic complex 0.8577716652396337 1.233363484168995 0.2174401822847973 1.0 0.628732233302689 3 Q14118 1 +Sodium ion import across plasma membrane 0.8568358850389619 1.232240376113565 0.2178593049129116 1.0 0.628732233302689 2 Q92581 1 +Gamma aminobutyric acid signaling pathway 0.8568358850389548 1.2322403761135363 0.2178593049129222 1.0 0.628732233302689 2 P04899 1 +Vascular wound healing 0.8568358850389477 1.232240376113508 0.2178593049129329 1.0 0.628732233302689 2 P43121 1 +Endosomal vesicle fusion 0.7141556479332782 1.231399151234954 0.21817361427047 1.0 0.628732233302689 4 Q9P2R3,Q9H270 2 +Mitotic nuclear membrane organization 0.6189546951930804 1.2310230452816289 0.21831424523136 1.0 0.628732233302689 7 Q6NUK4,Q86XL3,Q8IXJ6,Q9H6H4 4 +Alcohol biosynthetic process 0.4408581677402245 1.2308237349944673 0.2183887963684914 1.0 0.628732233302689 43 Q9NRA0,Q15392,O75845,P56937,Q13510,Q15800,P04062,O15269,Q9H2C2,Q16850 10 +Transepithelial chloride transport 0.8570660934981164 1.230703939219706 0.2184336142523149 1.0 0.628732233302689 3 P51798,Q86WC4 2 +Spontaneous synaptic transmission 0.857066093498116 1.2307039392197052 0.2184336142523151 1.0 0.628732233302689 3 P05067,P05556 2 +Regulation of spontaneous synaptic transmission 0.857066093498116 1.2307039392197052 0.2184336142523151 1.0 0.628732233302689 3 P05067,P05556 2 +Rho protein signal transduction 0.4641687636585631 1.229802561868302 0.218771048651428 1.0 0.628732233302689 29 O75955,P41440,O14786,Q9Y624,Q9Y6N7 5 +Regulation of mitochondrion organization 0.4361689226666836 1.227599964799852 0.2195971750460266 1.0 0.6292177285842113 49 O14965,P21796,P42858,P11233,Q9H4A6,Q8N2A8,Q9Y3D6,Q13501,P27544,O00429,Q9GZY8,Q99536,P30536,P02786,Q9UG56,Q14247,Q9NQ11 17 +Alpha beta t cell proliferation 0.8558328944312321 1.2260564849277238 0.2201774196550221 1.0 0.6303413355523103 3 P04439 1 +Mechanoreceptor differentiation 0.5811143180498973 1.2253030515895154 0.2204610590673952 1.0 0.6308195681871882 10 P54802 1 +Positive regulation of amyloid precursor protein biosynthetic process 0.8546870803115925 1.2235382051408237 0.2211264832741881 1.0 0.6318129657965582 2 Q92542 1 +Cholesterol storage 0.854916711445457 1.222604500493873 0.2214791124681245 1.0 0.6318129657965582 3 Q8WTV0,Q9H4M9 2 +Mannosylation 0.6040730994698407 1.220402785191442 0.2223122220550775 1.0 0.6334974433448449 8 O43505,Q9H9S5 2 +Fat soluble vitamin metabolic process 0.5914580029993672 1.2202173510650942 0.2223824910050136 1.0 0.6334974433448449 9 Q99538,P04062,P98164 3 +Regulation of system process 0.3941124752412547 1.2192059444911054 0.2227660362928964 1.0 0.633951363357876 72 Q13614,P04062,Q14118,P05067,P17301,P53634,P10253,Q9Y2Y6,P04899,P17612,P0DP25,O75844,P42892,Q14126,P17252,Q9UQB8,Q06787,P78310,P05026 19 +Glomerular epithelial cell differentiation 0.6659576859673779 1.2189655498169942 0.222857268288743 1.0 0.633951363357876 5 O00592 1 +Cytoplasm organization 0.7102929320075279 1.2157058242767729 0.2240970046869841 1.0 0.6362741507911739 4 Q9Y2W6,P33176,Q8N2A8 3 +Negative regulation of receptor internalization 0.6646244541553777 1.213350431939633 0.2249958689714293 1.0 0.6381389394187554 5 O00560,Q13614 2 +Protein kinase a signaling 0.5783194474185454 1.2115483679017875 0.2256853091355408 1.0 0.6388768690097628 10 O43164,P14174,P17612,P22694 4 +Glycerolipid biosynthetic process 0.4196421339600513 1.2114246922339371 0.2257326806647446 1.0 0.6388768690097628 60 Q8NCC3,P01130,Q8TCG2,Q9NYA4,Q9HCL2,Q9NX62,Q8WTV0,P35790 8 +Regulation of cation channel activity 0.4765751556947523 1.2090629357813123 0.2266386673334355 1.0 0.6406294173212504 23 P17252,P27105,P0DP25,Q06787,P17612,P05067,P05556 7 +Cobalamin transport 0.8511552928533017 1.2084393289275763 0.2268783196357537 1.0 0.6408868934099501 3 Q9NPF0,O14678 2 +Regulation of low density lipoprotein particle clearance 0.6429316268142934 1.2074309084583963 0.227266238240138 1.0 0.6415915453603223 6 P01130,P61978 2 +Positive regulation of monooxygenase activity 0.6423728109674517 1.2050088639515475 0.2281998800389701 1.0 0.6427337508757023 6 P0DP25,Q8WTV0,Q04656 3 +Positive regulation of protein serine threonine kinase activity 0.4391554285883502 1.2034472106277525 0.2288033078837772 1.0 0.6430589117553803 37 P14174,O14641,Q8NDZ4,P00533,P14635,Q14012,P0DP25,Q9Y6N7 8 +Negative regulation of amyloid precursor protein catabolic process 0.5878577763663583 1.2030160077920702 0.228970125999913 1.0 0.6431507897952293 9 Q92673 1 +Negative regulation of protein serine threonine kinase activity 0.4817248010123521 1.2021948077742262 0.2292880605306357 1.0 0.6433848987076798 22 P04062,Q92673 2 +Vesicle docking involved in exocytosis 0.5434263251407894 1.2018776330508287 0.2294109414697096 1.0 0.6433848987076798 13 Q15833,Q9H270,Q9UEU0,P56545 4 +Ammonium transmembrane transport 0.8493150684931496 1.2018091808467055 0.2294374676083788 1.0 0.6433848987076798 2 P55011 1 +Ameboidal type cell migration 0.4119641386618736 1.2012715370231428 0.2296458876217157 1.0 0.6437000162445584 91 Q99538,P17301,P05556,P42785,O95470,Q9Y6W5,P29317,Q07021,O94813,Q13685,Q06481,O95819,O14786,Q8WTV0,Q13641,Q9Y6N7 16 +Lactation 0.5331915401060603 1.2000097562869985 0.2301355513958298 1.0 0.6442641877422105 14 P19021,Q04656 2 +Protein localization to endosome 0.5227380937009782 1.1996491939180016 0.230275612419887 1.0 0.644387120850974 15 Q92673,Q9NV96 2 +Positive regulation of fatty acid metabolic process 0.7059712422743095 1.198155363794857 0.2308565387811847 1.0 0.6451965493824491 4 P31751 1 +Blood vessel morphogenesis 0.4215312999652584 1.1972707732801526 0.2312010322758728 1.0 0.6451965493824491 98 P42785,O14964,Q9Y6W5,P23458,Q14344,Q14118,P35613,P06756,O95470,Q9H2J4,P98164,P01130,P29317,Q13685,O14786,P05556,Q04721,Q08431,O94813,P43121,Q9H6E4,Q9BUP3,Q07954,Q9Y6N7 24 +Regulation of cytoplasmic transport 0.5113153853568414 1.1964861672807867 0.231506893444678 1.0 0.6451965493824491 16 Q13614,Q92673,Q9H270,Q9Y3E7,Q93009 5 +Cellular hormone metabolic process 0.5022726197273052 1.195802813571353 0.2317735177140358 1.0 0.6451965493824491 18 P42892,Q9HB40,O95470 3 +Regulation of bicellular tight junction assembly 0.5987737553273083 1.1957559912965965 0.2317917943496876 1.0 0.6451965493824491 8 P29317,Q9Y624,P17612 3 +Arf protein signal transduction 0.6603295242558618 1.1952625930989675 0.2319844499169483 1.0 0.6451965493824491 5 O95819 1 +Regulation of reactive oxygen species biosynthetic process 0.5860178190976284 1.1942205453714996 0.2323917083615918 1.0 0.6452237679648745 9 P51790 1 +Negative regulation of voltage gated calcium channel activity 0.8474348643567065 1.1942134089784842 0.2323944991915338 1.0 0.6452237679648745 2 Q06787 1 +Terpenoid metabolic process 0.4863058500167153 1.19387963148368 0.2325250561625294 1.0 0.6452237679648745 21 Q9HB40,P98164 2 +G protein coupled acetylcholine receptor signaling pathway 0.8471662637657893 1.1931287124118564 0.232818968173021 1.0 0.6453071648865125 2 P04899 1 +Deoxyribose phosphate metabolic process 0.5207191748364046 1.1880582985152572 0.2348104422319399 1.0 0.6489243916526456 15 Q9H773 1 +Positive regulation of translation 0.4189001863534418 1.1878344894496375 0.2348986234182808 1.0 0.6489243916526456 59 P17301,P98179,Q13217,Q14103,Q9Y2R0,O15031,Q07021,Q567V2,O60506,P51114,Q06787,P67809,Q07666,P51116,Q9P2X3,Q14011,O00571,P08670 18 +Cell fate specification 0.5845373358717932 1.187141411028897 0.2351718463314096 1.0 0.6494115014887134 9 Q96KQ7,O14786 2 +Cellular response to sterol 0.8455546602202682 1.1866227486400591 0.235376458695965 1.0 0.6494397215384489 2 Q14118 1 +Cellular response to cholesterol 0.8455546602202682 1.1866227486400591 0.235376458695965 1.0 0.6494397215384489 2 Q14118 1 +Negative regulation of collateral sprouting 0.8450174590384265 1.1844549488819465 0.236233019701348 1.0 0.6505354902343844 2 Q15375 1 +Cellular glucan metabolic process 0.5000290357555236 1.1819819357600354 0.2372128686068704 1.0 0.6523597231855747 18 Q8TDY2,P31751,Q93100,P10253 4 +Epithelial cell proliferation 0.4165097294548789 1.180973959606642 0.2376130681916783 1.0 0.6529244702831605 60 Q04721,P29317,Q92542,Q04656,P00533,Q6YHK3,O14786,Q8WTV0,Q9H2J4,Q9Y6N7 10 +Regulation of signaling receptor activity 0.4996942375572078 1.1799184710677846 0.2380326426657439 1.0 0.6533664950600637 18 P05067,Q9BRG1,O14786 3 +Melanocyte differentiation 0.8430951101558283 1.1781271000615634 0.2387459396532825 1.0 0.6544275204729241 3 P29992,Q86YV9 2 +Positive regulation of map kinase activity 0.5186068299573172 1.1759226395001698 0.2396257910870374 1.0 0.6556454109844904 15 P00533,P14174,Q9Y6N7 3 +Positive regulation of interleukin 6 production 0.5596336012745775 1.1758520017856997 0.2396540219935428 1.0 0.6556454109844904 11 P05067 1 +Cellular sodium ion homeostasis 0.7001344393607144 1.174467490933041 0.2402078258887541 1.0 0.6560199059113407 4 P05026,P55011 2 +Cellular potassium ion homeostasis 0.7001344393607144 1.174467490933041 0.2402078258887541 1.0 0.6560199059113407 4 P05026,P55011 2 +Positive regulation of nitric oxide synthase activity 0.8417517463729152 1.173081079152391 0.2407632932641283 1.0 0.6570014623192949 3 Q8WTV0,P0DP25 2 +Response to estrogen 0.527702831018705 1.169454065106041 0.2422207379999781 1.0 0.6599038154779892 14 Q13772 1 +Response to interferon gamma 0.4638373537972208 1.1668859552597337 0.2432564284659371 1.0 0.6606113075323574 26 Q08722,O60506,P23458,Q9UNK0,Q13137,P08670 6 +Regulation of fibroblast migration 0.5923454635341941 1.1658346502166934 0.2436813047607713 1.0 0.6606544850736831 8 Q06481 1 +Positive regulation of skeletal muscle tissue development 0.6978871007739397 1.1653525030840897 0.2438763348362118 1.0 0.6606544850736831 4 P41440 1 +Fatty acid transport 0.492113662541183 1.162871358016381 0.2448816997958374 1.0 0.6620399967856806 19 P31751,P14174,P23786,P11166 4 +Inositol phosphate metabolic process 0.5680639142595765 1.1610082305229836 0.2456385523500208 1.0 0.6627695824909241 10 Q9BW91,Q9NX62,Q13614,Q9UNW1,Q13572,Q96PE3 6 +Positive regulation of carbohydrate metabolic process 0.5909915809239149 1.1595299896544564 0.2462402195884701 1.0 0.6632010127616051 8 P05067 1 +Neuronal action potential 0.6515960377108321 1.1584920945573751 0.2466632759281792 1.0 0.6632010127616051 5 P04062 1 +Protein o linked glycosylation 0.4961818083537331 1.158254320914485 0.2467602664775678 1.0 0.6632010127616051 18 Q86SF2,O43505,Q10472,Q9H9S5,Q10471,Q9Y2G5 6 +Leukocyte apoptotic process 0.4685782140135833 1.154353501245898 0.248355270401116 1.0 0.6655245990516913 23 Q9HCL2,P24390,P07711 3 +Response to camp 0.5552418672926338 1.153511583788551 0.2487004657476377 1.0 0.665558495788819 11 P05067 1 +Tissue morphogenesis 0.4104634169803136 1.1534808754036212 0.2487130628600438 1.0 0.665558495788819 93 P22694,Q14118,P00533,Q8TAA9,P17301,Q14517,P11233,O15031,Q5SZK8,P10644,P67870,Q9Y2G5,P98164,P29317,Q04656,O14786,P05556,Q04721,O94813,O00592,Q15375,Q9Y6N7 22 +Developmental cell growth 0.4267393690244893 1.1518673343819013 0.2493755931796066 1.0 0.6658625362121651 50 O14965,Q9P265,Q92581,O94813,Q13740,Q15375,Q9P2X3,P05067,O14786,P51805,P05556 11 +Response to bacterium 0.3853539870772711 1.1517202760176437 0.2494360375658448 1.0 0.6658625362121651 73 Q04721,P04439,O43405,P01889,P29317,Q9BTY2,Q5KU26,Q8WTV0 8 +Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning 0.8358409457281011 1.1509010016297372 0.2497729656874634 1.0 0.6658625362121651 3 P17612,P22694 2 +High density lipoprotein particle assembly 0.8358409457281011 1.1509010016297372 0.2497729656874634 1.0 0.6658625362121651 3 P17612,P22694 2 +Smoothened signaling pathway involved in dorsal ventral neural tube patterning 0.8358409457281011 1.1509010016297372 0.2497729656874634 1.0 0.6658625362121651 3 P17612,P22694 2 +Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning 0.8358409457281011 1.1509010016297372 0.2497729656874634 1.0 0.6658625362121651 3 P17612,P22694 2 +Response to parathyroid hormone 0.8358409457281009 1.150901001629736 0.2497729656874638 1.0 0.6658625362121651 3 P17301,P17612 2 +Amino acid import 0.5765663396891765 1.1489988036398335 0.2505564739755304 1.0 0.667515714752047 9 P05556,P08195,P30825 3 +Positive regulation of lipopolysaccharide mediated signaling pathway 0.835616438356177 1.1465918988156163 0.2515503262074672 1.0 0.6676793212841968 2 P14174 1 +Cellular response to parathyroid hormone stimulus 0.8356164383561631 1.1465918988155614 0.2515503262074898 1.0 0.6676793212841968 2 P17612 1 +Anatomical structure arrangement 0.8344975819451885 1.1458654305192209 0.2518508369257914 1.0 0.6679478864569269 3 P51805,O14786 2 +Camp mediated signaling 0.6923573211571468 1.1429394612344896 0.2530637270984353 1.0 0.669358523120934 4 O60291 1 +Cyclic gmp amp transmembrane import across plasma membrane 0.8336497935380021 1.142688582004134 0.2531679121201589 1.0 0.669358523120934 3 P41440 1 +Response to lead ion 0.6476734536707175 1.1419842914107186 0.2534605492661801 1.0 0.669358523120934 5 P05067 1 +Response to ketone 0.4287964560361309 1.14167591493537 0.2535887557367156 1.0 0.669358523120934 46 P16278,Q13185,Q9NRA0,Q969T9,O95831,O43823,O94813,P04062,O60266,P63096,Q14103,Q13772,Q05086 13 +Small gtpase mediated signal transduction 0.4354742381662365 1.139254408113444 0.2545970583423265 1.0 0.6699410656518293 112 Q9Y6W5,Q13501,P80303,Q14344,O75955,Q9Y624,Q9Y2I1,Q02818,P06756,P11233,P53365,P62993,Q15392,O95819,P61225,O14786,P41440,Q7Z569,Q9H0H5,P05556,Q04721,Q14185,Q15058,P51151,O94813,O00560,Q86VI3,Q9Y6N7 28 +Receptor localization to synapse 0.5222593353458096 1.1391017396519367 0.2546607220051582 1.0 0.6699410656518293 14 Q14168,P33176,Q14118,O15400 4 +Regulation of membrane permeability 0.4882706357161351 1.1386693979899958 0.2548410711453719 1.0 0.6699410656518293 19 P45880 1 +Regulation of secretion 0.4271198573701809 1.1372343511946477 0.2554403303155039 1.0 0.6702364712787052 106 P14174,P51149,Q9Y3E7,P55011,P19021,Q8IWT6,P11233,Q9NRA0,Q32P28,Q16850,P04899,P51809,P0DP25,Q9NQ11,Q9Y2G5,Q4J6C6,O00429,O14936,P11279,Q7L0J3,P51151,Q96KC8,Q06787,O00213,Q92783,O00560,Q9H3S7,Q15833,O14964 29 +Response to cholesterol 0.832146723759396 1.13705832573029 0.255513903926752 1.0 0.6702364712787052 3 Q14118 1 +Response to sterol 0.832146723759396 1.13705832573029 0.255513903926752 1.0 0.6702364712787052 3 Q14118 1 +Interleukin 1 production 0.5217523044067707 1.136272309029148 0.2558426161522562 1.0 0.6704431525768985 14 P05067 1 +Potassium ion export across plasma membrane 0.8326618318560324 1.1347226854517012 0.2564915291944465 1.0 0.6711047731272114 2 Q4KMQ2 1 +Regulation of potassium ion export across plasma membrane 0.8326618318560324 1.1347226854517012 0.2564915291944465 1.0 0.6711047731272114 2 Q4KMQ2 1 +Positive regulation of g protein coupled receptor signaling pathway 0.645518893587107 1.1329197215457878 0.2572479672367205 1.0 0.67115043717172 5 Q15043 1 +Renal filtration 0.8309475044206566 1.132568184303985 0.257395635733388 1.0 0.67115043717172 3 Q96J84 1 +Response to cocaine 0.5970123107207159 1.1316216989195012 0.2577935134479949 1.0 0.6714455091753507 7 Q96KQ7 1 +Inositol phosphate catabolic process 0.6449541116153616 1.1305439499197438 0.258247090140882 1.0 0.6716084218692516 5 Q9NX62 1 +Branchiomotor neuron axon guidance 0.830283105545166 1.1300812835120695 0.2584419755298119 1.0 0.6716084218692516 3 O14786 1 +Regulation of homophilic cell adhesion 0.8313188289014368 1.129332754712444 0.2587574883636288 1.0 0.6720013530062626 2 Q9P273 1 +Positive regulation of pattern recognition receptor signaling pathway 0.5616284308511775 1.1292468454082436 0.2587937171156615 1.0 0.6720013530062626 10 Q9NUD5,O43164,O75955,P41440 4 +Plasma membrane phospholipid scrambling 0.8297042312928655 1.1279149532002748 0.2593558381370866 1.0 0.6727957664818378 3 Q7Z3C6 1 +Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway 0.6877794389265461 1.124403115630456 0.2608420509150533 1.0 0.6737438859523286 4 P04899 1 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.5606331388248156 1.1243320537978638 0.2608721850263045 1.0 0.6737438859523286 10 P67809,O60506 2 +Negative regulation of fatty acid transport 0.8297072253559048 1.1228692197765664 0.2614930418010943 1.0 0.6741955556537396 2 P31751 1 +Mitochondrial fusion 0.4988844503753045 1.1226149024261578 0.2616010834378546 1.0 0.6741955556537396 16 Q9NWX6,Q8N2A8,Q9GZY8,Q99536,P02786,O95140,Q9Y3D6,Q8IWA4 8 +Negative regulation of protein containing complex assembly 0.4289200098570342 1.1210882307383696 0.2622503078777609 1.0 0.6752214995761636 40 P45880,Q92673,O94813 3 +Cellular response to cold 0.8277807630306264 1.120719751593811 0.2624071719870517 1.0 0.675313297637776 3 P17252,P17612 2 +Integrin mediated signaling pathway 0.4799960563004308 1.1178666968161377 0.263623930473386 1.0 0.6763046116515651 20 P17301,P06756,Q08722,O14786 4 +Phosphatidylinositol phosphate biosynthetic process 0.5184535338918871 1.1178549795429538 0.2636289356180397 1.0 0.6763046116515651 14 Q9BTU6,Q8TCG2,Q9NX62 3 +Regulation of protein serine threonine kinase activity 0.3873821447671654 1.1178526231353232 0.2636299421878827 1.0 0.6763046116515651 71 P14174,O14641,Q8NDZ4,Q99640,P04062,P00533,Q92673,P10644,Q14012,P14635,P0DP25,Q9Y6N7,O14964 13 +Tor signaling 0.4628581903038517 1.1150957754491997 0.2648093816468695 1.0 0.6777926779289983 23 O75663,Q9Y2Q5,Q9H4A6,O75844,P04062,Q8NHS3 6 +Regulation of establishment of planar polarity 0.593182178277706 1.114257100191764 0.2651689054714543 1.0 0.6782571992676191 7 O14641,Q8TAA9 2 +Stress activated protein kinase signaling cascade 0.4260012222257546 1.1120482959697051 0.2661173855664904 1.0 0.6794302286285526 45 O75844,Q96J02,P00533,O95819,O00560,P05067,Q8TDY2 7 +3 phosphoadenosine 5 phosphosulfate metabolic process 0.6402182967100403 1.1106291416895933 0.2667280137210377 1.0 0.6797000562579447 5 Q8TB61,O43252 2 +Regulation of production of small rna involved in gene silencing by rna 0.5919170458869805 1.108521190885983 0.2676367925360727 1.0 0.6806400742734696 7 O75844 1 +Single fertilization 0.45313478950574 1.107889923709523 0.2679093577937053 1.0 0.6806400742734696 27 P07686,Q08431,P45880 3 +Ectodermal placode development 0.6835291753388106 1.1072104374492049 0.2682029559342922 1.0 0.6810260580706847 4 O14786 1 +Regulation of protein tyrosine kinase activity 0.5064772074660536 1.1060845924497054 0.2686899069047865 1.0 0.6810260580706847 15 P05067,O14641,Q9BRG1 3 +Activation of immune response 0.4185189202352282 1.1055185196870936 0.2689349741726139 1.0 0.6810260580706847 53 P04439,Q9NUD5,Q07021,Q08722,Q07666,Q06481,Q7KYR7,P07947,Q5ZPR3,Q92692 10 +Cardiac ventricle development 0.4828751988432733 1.1046334317186617 0.2693184586861061 1.0 0.6810260580706847 19 P16870,Q9Y6N7,O94813,P98164 4 +Epoxide metabolic process 0.825141015310243 1.1045827500925909 0.26934042900871 1.0 0.6810260580706847 2 P34913 1 +Regulation of postsynaptic membrane neurotransmitter receptor levels 0.5456337170478338 1.1045724275877025 0.2693449039322915 1.0 0.6810260580706847 11 Q15334,Q12959,Q14118,O60716,Q96RT1,Q14254 6 +Regulation of phospholipase activity 0.5563756685889565 1.10330157951203 0.2698962209210178 1.0 0.6813210480799571 10 Q07954,P50897 2 +Positive regulation of cytoplasmic translation 0.5561732118366625 1.1023012546217417 0.2703307241126169 1.0 0.6818805092219642 10 P67809,O60506 2 +Peptidyl lysine dimethylation 0.5903826205042068 1.1015643365916894 0.270651119998355 1.0 0.6822668547571455 7 Q96KQ7 1 +Transmission of nerve impulse 0.578532874418468 1.1014807195140393 0.2706874913159132 1.0 0.6822668547571455 8 P17301,P04062 2 +Negative regulation of wound healing 0.5781222265739276 1.0995666917476292 0.2715209611795837 1.0 0.6838532438277226 8 O14936,P55011,Q6YHK3 3 +Glutathione catabolic process 0.8235294117647215 1.0981385301658086 0.27214400286275 1.0 0.684910510176444 2 Q9UJ14 1 +Positive regulation of membrane protein ectodomain proteolysis 0.820428435764496 1.09326170432112 0.274278911897746 1.0 0.6876981921207235 3 O43847 1 +Positive regulation of autophagy of mitochondrion 0.6155820250761267 1.0888855814781482 0.2762043453047671 1.0 0.690423828224986 6 P21796 1 +Organic hydroxy compound biosynthetic process 0.4018136798920544 1.0883946992385676 0.2764209002345972 1.0 0.690423828224986 63 Q9BXW6,Q9NRA0,Q15392,O75845,P56937,Q13510,Q04656,Q15800,P04062,O15269,Q9H2C2,Q16850 12 +Response to retinoic acid 0.5127757990738147 1.086122158953575 0.2774249499273402 1.0 0.6909334873329744 14 P11717 1 +Positive regulation of mitochondrial fission 0.5630906242984273 1.0844339151941558 0.2781724530865064 1.0 0.6917741909724539 9 O14965,P11233,O00429,Q9GZY8,Q9Y3D6 5 +Calcium ion import into sarcoplasmic reticulum 0.8200376040827457 1.0841944177774678 0.2782786062163138 1.0 0.6917741909724539 2 O75844 1 +Negative regulation of receptor binding 0.8200376040827457 1.0841944177774678 0.2782786062163138 1.0 0.6917741909724539 2 P10586 1 +Xenobiotic transport across blood brain barrier 0.819769003491805 1.0831228593797444 0.2787538937464728 1.0 0.6923346667780189 2 P33527 1 +Sphingolipid translocation 0.819769003491805 1.0831228593797444 0.2787538937464728 1.0 0.6923346667780189 2 P33527 1 +Intermembrane lipid transfer 0.5744655593908747 1.0825221442127084 0.2790205811649402 1.0 0.6923346667780189 8 Q96CP6,P61916,Q9H1P3 3 +Negative regulation of glial cell differentiation 0.6772330882299595 1.081776567253039 0.279351821234586 1.0 0.6926491328001888 4 P01130 1 +Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.4920320080955292 1.0817716322489557 0.2793540146163698 1.0 0.6926491328001888 16 Q04721,O00560,Q92859 3 +Estrogen metabolic process 0.6133165236145082 1.079072836151883 0.2805552594490237 1.0 0.6941823936070585 6 P56937,O95470 2 +Regulation of dephosphorylation 0.4237562245370694 1.0785216509669882 0.2808010249281909 1.0 0.6941823936070585 35 O75663,P17301,Q86XL3,Q9NYA4,P42345,Q13614,P04062,P67870,P04899,P0DP25,P78318 11 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.5510433630894616 1.076948508647523 0.281503270098359 1.0 0.6948212972793193 10 Q07021,O43657 2 +T cell receptor signaling pathway 0.4511448343973582 1.0762411608918026 0.2818194156935163 1.0 0.6948212972793193 26 Q07666,P04439,Q92692,Q7KYR7 4 +Antigen receptor mediated signaling pathway 0.4511448343973582 1.0762411608918026 0.2818194156935163 1.0 0.6948212972793193 26 Q07666,P04439,Q92692,Q7KYR7 4 +Regulation of response to cytokine stimulus 0.4552981746238322 1.075779350247874 0.2820259495926023 1.0 0.6948212972793193 24 O94813,Q9Y6N7 2 +Regulation of endocytic recycling 0.6318049976072149 1.0752850256263644 0.2822471383261986 1.0 0.6948212972793193 5 Q92673 1 +Negative regulation of cell aging 0.6316646569430691 1.0746959055129417 0.2825108975061392 1.0 0.6948212972793193 5 P67809 1 +Regulation of microtubule based movement 0.6119101458924895 1.0729824744033165 0.2832789795068215 1.0 0.6959441791256298 6 P11279,Q7Z4L5 2 +Regeneration 0.4231187138901299 1.0707834380070225 0.2842668154980361 1.0 0.697175434920187 38 Q96G23,Q14118,P10586,P11717 4 +Response to alcohol 0.4200056101620529 1.0701328213824353 0.2845595274167094 1.0 0.697175434920187 47 P16278,Q9NRA0,O95831,O43823,O94813,Q14118,O60266,P63096,Q96KQ7 9 +Negative regulation of regulated secretory pathway 0.6304723313475775 1.0696914392755952 0.2847582209533759 1.0 0.697175434920187 5 P04899 1 +Peptidyl tyrosine dephosphorylation 0.4899443195811455 1.0693132956983615 0.2849285215257493 1.0 0.697175434920187 16 Q3ZCQ8,Q9NYA4,Q9ULE6,Q13614,P10586 5 +L alpha amino acid transmembrane transport 0.5275578811897568 1.0690767050598902 0.2850351074070241 1.0 0.697175434920187 12 Q9Y619,P08195,P30825 3 +Regulation of inclusion body assembly 0.5598182179858893 1.0687456833272546 0.2851842804669848 1.0 0.697175434920187 9 Q92673,Q9UL15 2 +Protein localization to postsynapse 0.583142644080469 1.0687419991029838 0.2851859410386868 1.0 0.697175434920187 7 Q12959,Q14118,Q15334 3 +Non canonical wnt signaling pathway 0.5831178978509197 1.0686298270313166 0.2852365029172117 1.0 0.697175434920187 7 O14641,Q8TAA9 2 +Positive regulation of fibroblast proliferation 0.5595094809605271 1.0672654659307663 0.2858519777835715 1.0 0.6974204011829717 9 P00533,P14174 2 +Regulation of post translational protein modification 0.8134452793748055 1.0672542656708477 0.2858570340270998 1.0 0.6974204011829717 3 Q32P28 1 +Cerebral cortex development 0.4392032071302055 1.0656503873277938 0.2865817126800598 1.0 0.6979842225445395 30 P62995,P19022,Q15058,Q96QD8,O94813,P00533,P07942,P11166,Q9Y6N7 9 +Divalent inorganic cation homeostasis 0.395751746148009 1.0655903571714678 0.2866088601078145 1.0 0.6979842225445395 65 P06756,P17252,Q9NWR8,Q8NE01,Q9HD20,Q9H7F0,P98194,P0DP25,Q14344,P07686,Q15043,P17612,P05026,Q6P4Q7,P05067,Q8NEN9,Q9NQ11,Q7L0J3 18 +Regulation of cell projection assembly 0.411769787679471 1.0647925435269312 0.2869698201551494 1.0 0.6983557497021826 55 P11233,P29317,Q16625,O94813,Q04656,P51114,O00592,Q06787,P51116,O14786 10 +Regulation of peptidyl serine phosphorylation 0.4471311954107133 1.0643251935650777 0.2871814088382989 1.0 0.6984773084128393 27 P02786,P05067,P14174 3 +Regulation of lipoprotein metabolic process 0.5821454309888915 1.0642218525990017 0.2872282097860019 1.0 0.6984773084128393 7 P04062,P06756 2 +Establishment of epithelial cell apical basal polarity 0.6095790916503863 1.062890018170262 0.2878318302223936 1.0 0.6991840979160864 6 Q14517 1 +Determination of adult lifespan 0.5577742628678712 1.0589458533799216 0.2896244399633636 1.0 0.7023685830841703 9 P04062 1 +Developmental induction 0.8103600115844529 1.055788028933882 0.2910650686356928 1.0 0.7034709031546957 3 Q9Y6N7 1 +Anterograde dendritic transport 0.8103425335614088 1.0557231171436476 0.2910947324523079 1.0 0.7034709031546957 3 Q14254 1 +Cellular modified amino acid metabolic process 0.4003014710652482 1.0551319721287629 0.291364971345496 1.0 0.7034709031546957 62 Q9UHG3,Q9H2D1,P07858,Q9UJ14,P23786,Q92820,Q8NCC3 7 +Positive regulation of b cell activation 0.5161274760695811 1.0540629223165332 0.291854110134758 1.0 0.703639448357348 13 P02786,Q9NPF0 2 +Cellular defense response 0.6703563256298473 1.054050517769736 0.2918597890142766 1.0 0.703639448357348 4 Q08380 1 +Positive regulation of cell size 0.6702050576256587 1.0534413189167726 0.2921387754482845 1.0 0.7040323887286597 4 Q04656 1 +Positive regulation of cyclin dependent protein kinase activity 0.6069686771024793 1.0515917490846862 0.2929868949124177 1.0 0.704788448553643 6 P00533 1 +B cell activation 0.4195783754420087 1.0485112705503756 0.294403112368967 1.0 0.7050222435827641 43 Q04721,Q9NPF0,P14174,P13051,P02786,Q9UQ84 6 +Carbohydrate metabolic process 0.4944474739888985 1.0466670070650774 0.2952531855499953 1.0 0.705701444206872 166 P33908,Q86SF2,P43304,O43505,Q04446,Q9HAT2,Q8IW92,Q9BRR6,Q9BTY2,Q9NX62,Q7LGA3,P06280,P05067,P17900,P16278,Q16706,P06865,O00462,P10253,Q92520,P07686,P08236,P11166,Q14108,Q01459,Q8NCH0,O75844,O94766,P48735,P04066,Q8N6G5,Q15043,Q99519,O00754,P31751,O60512,Q8NBZ7,Q93100,P08195,Q8TDY2 40 +Bile acid metabolic process 0.4959858866396843 1.0455031161132446 0.2957905011409552 1.0 0.7059050986264631 15 Q9H2C2,O15118 2 +Lipid catabolic process 0.4020155964473607 1.0447143049512215 0.296155031375191 1.0 0.7059050986264631 94 Q92485,Q8NHP8,P23786,P04062,P06280,Q8WTV0,P17900,P50897,P06865,Q92484,Q13510,P07686,Q92673,P38571,P01130,Q2T9J0,Q8NCC3,P04066,Q99519 19 +Negative regulation of amyloid fibril formation 0.5775767805905329 1.0435168963100707 0.2967089595301027 1.0 0.7059050986264631 7 P01130,O15212 2 +Cellular response to cadmium ion 0.5774436898571176 1.0429138431158105 0.2969881976526793 1.0 0.7059050986264631 7 P00533 1 +Heparan sulfate proteoglycan biosynthetic process 0.565564649911744 1.0410335464143428 0.2978599792519543 1.0 0.7059050986264631 8 Q99805,Q7LGA3 2 +Demethylation 0.4771173059349126 1.0402175099443591 0.2982388582744539 1.0 0.7059050986264631 18 Q9UPP1,Q8NB78 2 +Nuclear membrane organization 0.4575392686997164 1.039739464912985 0.2984609601014614 1.0 0.7059050986264631 22 Q86XL3,Q8IXJ6,P17252,Q6NUK4,Q9H6H4,Q9Y3E7,Q9NZZ3,P50402,O75531 9 +Microvillus organization 0.5431148062446274 1.0377462326518188 0.2993882146848725 1.0 0.7059050986264631 10 O00592,O95819 2 +Regulation of cell morphogenesis 0.3737805529970305 1.0344880377743924 0.3009080662026002 1.0 0.7079112068875394 75 O14641,O43405,O15031,Q14185,Q07021,Q9UQB8,Q8WWQ0,O75844,Q14344,Q14118,P07686,Q12959,P46108,O14786,Q8NEN9,P51805,Q9Y624 17 +Organic hydroxy compound catabolic process 0.4938461597352531 1.0331314371285705 0.3015423932636425 1.0 0.7088520237295448 15 Q8WTV0,P43304,Q9NX62 3 +Response to interleukin 1 0.4713793914655558 1.0319172082419843 0.3021109038337495 1.0 0.709647758370531 19 P05067,Q08722 2 +Regulation of lipid localization 0.4374010189289194 1.0306269566439537 0.3027157898959294 1.0 0.709734759218409 29 Q07954,P06756,O15260,P14174,P31751,Q9H2C2,Q9NV96,Q8WTV0 8 +Androgen metabolic process 0.6018537918684113 1.0294669286623988 0.3032603126359261 1.0 0.709734759218409 6 O95470 1 +Epidermis development 0.4040183783098995 1.0291526525693808 0.3034079473687574 1.0 0.709734759218409 58 Q8TEL6,Q08J23,P29317,Q13510,Q04656,O75844,Q14145,P00533,P67809,Q16739,Q6YHK3,Q14254,Q9Y6M7 13 +T cell activation involved in immune response 0.5515087499308287 1.0289042758635265 0.3035246589094456 1.0 0.709734759218409 9 Q9NQZ7,P42345,Q04656,Q9Y2Y6 4 +Energy reserve metabolic process 0.4660002116287857 1.0275284414574266 0.3041717000496704 1.0 0.709734759218409 20 Q8TDY2,P31751,Q93100,P10253 4 +Viral budding 0.5303442737159576 1.0265703796925971 0.3046228075414803 1.0 0.709734759218409 11 Q9UK41,Q9H9H4,Q9Y3E7,P46934 4 +Potassium ion import across plasma membrane 0.5509476047924413 1.0262138064760895 0.3047908149165947 1.0 0.709734759218409 9 Q9BXP2,Q9Y666,P05026,P55011 4 +Positive regulation of phosphatidylinositol 3 kinase signaling 0.6009195567191457 1.025427943113803 0.3051613089546938 1.0 0.709734759218409 6 P46934 1 +Positive regulation of signaling receptor activity 0.6007859273991998 1.0248502803239417 0.3054338376299199 1.0 0.709734759218409 6 O14786 1 +Protein exit from endoplasmic reticulum 0.4497402018599771 1.0247167225975653 0.3054968702156606 1.0 0.709734759218409 23 Q9BVK6,Q9NR31,Q92673,Q9NV96,Q92544,O15260 6 +Negative regulation of exocytosis 0.5505370671292137 1.024245464571617 0.3057193494263339 1.0 0.709734759218409 9 Q06787,P04899,P51149 3 +Cellular component disassembly involved in execution phase of apoptosis 0.5618923051781781 1.0239200690187875 0.3058730301794288 1.0 0.709734759218409 8 O00115 1 +T helper 1 cell differentiation 0.6627497640012332 1.0234573421515614 0.3060916592003928 1.0 0.709734759218409 4 Q9Y2Y6,P42345 2 +T helper 1 type immune response 0.6627497640012332 1.0234573421515614 0.3060916592003928 1.0 0.709734759218409 4 Q9Y2Y6,P42345 2 +Body morphogenesis 0.5401132868391743 1.0229025576469104 0.306353920098203 1.0 0.709734759218409 10 Q14118,O75787 2 +Respiratory chain complex iii assembly 0.8013837818036835 1.0225206254815602 0.3065345557742198 1.0 0.709734759218409 3 Q69YU5 1 +Response to dietary excess 0.6625089514292226 1.0224902282453707 0.306548935246635 1.0 0.709734759218409 4 Q92673 1 +Cranial ganglion development 0.8039215686274696 1.020194030573618 0.3076364481541609 1.0 0.709734759218409 2 O14786 1 +Ganglion development 0.8039215686274696 1.020194030573618 0.3076364481541609 1.0 0.709734759218409 2 O14786 1 +Dorsal root ganglion development 0.8039215686274696 1.020194030573618 0.3076364481541609 1.0 0.709734759218409 2 O14786 1 +Sympathetic ganglion development 0.8039215686274696 1.020194030573618 0.3076364481541609 1.0 0.709734759218409 2 O14786 1 +Morphogenesis of an epithelial fold 0.8039215686274673 1.0201940305736097 0.3076364481541649 1.0 0.709734759218409 2 P00533 1 +Canonical wnt signaling pathway involved in regulation of cell proliferation 0.8039215686274557 1.0201940305735635 0.3076364481541866 1.0 0.709734759218409 2 O14641 1 +Detection of muscle stretch 0.8039215686274498 1.0201940305735395 0.3076364481541982 1.0 0.709734759218409 2 P19022 1 +Synaptic vesicle clustering 0.8039215686274498 1.0201940305735395 0.3076364481541982 1.0 0.709734759218409 2 P19022 1 +Lung associated mesenchyme development 0.8039215686274466 1.0201940305735264 0.3076364481542044 1.0 0.709734759218409 2 Q13308 1 +Negative regulation of macroautophagy 0.5180532906216659 1.0189733206340046 0.3082156326660707 1.0 0.7099853080507709 12 O15118 1 +Pteridine containing compound metabolic process 0.4777393747415628 1.0188620943390765 0.3082684415175918 1.0 0.7099853080507709 17 Q92820,Q9H2D1 2 +Zinc ion homeostasis 0.6181608642197933 1.0180970912958085 0.3086318175208133 1.0 0.7101955506289718 5 Q15043 1 +Negative regulation of cell adhesion 0.4162354259957501 1.0167148807762465 0.3092890846349689 1.0 0.7107304002696218 35 O00592,P10644,Q96J02,O14936,O95819,P51805 6 +Positive regulation of neuron apoptotic process 0.5282947229371334 1.016107597964108 0.3095781513023574 1.0 0.7107304002696218 11 O95831,Q15375 2 +Cellular extravasation 0.5487579579677242 1.0157157375816914 0.3097647715887146 1.0 0.7107304002696218 9 P05556,Q08722,P46108,Q9Y624 4 +Embryonic hemopoiesis 0.5979382286724246 1.0125436413095052 0.3112781913000293 1.0 0.7137141423512817 6 Q9H6E4,Q13188 2 +Synaptic transmission dopaminergic 0.6161158499018532 1.0095431999457174 0.3127141944376528 1.0 0.7143793552550488 5 P41440 1 +Positive regulation of granulocyte chemotaxis 0.6160219504736337 1.0091505627897328 0.312902431850834 1.0 0.7143793552550488 5 Q07021 1 +Positive regulation of neutrophil migration 0.6160219504736337 1.0091505627897328 0.312902431850834 1.0 0.7143793552550488 5 Q07021 1 +Negative regulation of transport 0.3859826726618812 1.0083523989295655 0.3132853161251463 1.0 0.7143793552550488 85 Q13438,Q13614,P05067,P06756,Q06481,Q16850,P04899,P0DP25,P22413,Q08722,O00308,Q04656,P46934,Q99728,P21796,Q9UKS6,P31751,Q06787,O00560,Q9Y3D6 20 +Amino acid import across plasma membrane 0.569751234464969 1.008072500356232 0.3134196582578394 1.0 0.7143793552550488 7 P08195,P30825 2 +Regulation of sterol transport 0.5368735166389769 1.0068804899205863 0.3139922086807132 1.0 0.7143793552550488 10 Q07954 1 +Inclusion body assembly 0.5367821474068102 1.0064286384274117 0.3142094232172112 1.0 0.7143793552550488 10 Q92673,Q9UL15 2 +Water homeostasis 0.5156379779871664 1.0062345751122763 0.3143027438724433 1.0 0.7143793552550488 12 P04062,Q16739,P17612,P22694 4 +Negative regulation of tumor necrosis factor superfamily cytokine production 0.6147992893071532 1.004039082672939 0.315359775886755 1.0 0.7152423749553408 5 O43823,Q9UBC1 2 +Regulation of organic acid transport 0.5149074265706051 1.0023811977701556 0.3161595195611699 1.0 0.7162773396537638 12 P14174,P31751,P55011,Q7L0J3,P05556 5 +Neural plate development 0.7951156130614521 0.9993780536009896 0.3176115871029372 1.0 0.7175558925983639 3 O14641 1 +Polysaccharide catabolic process 0.5673139739638884 0.9970406331250818 0.3187447872973692 1.0 0.7184002711801696 7 P10253 1 +Cellular polysaccharide catabolic process 0.5673139739638884 0.9970406331250818 0.3187447872973692 1.0 0.7184002711801696 7 P10253 1 +Vasculogenesis 0.5346838885546211 0.9960523287865968 0.3192247204783591 1.0 0.7184002711801696 10 P29317,P06756 2 +Protein o linked glycosylation via serine 0.6558670343083743 0.9958535829500724 0.3193212910745089 1.0 0.7184002711801696 4 Q10472 1 +Digestive tract morphogenesis 0.6556175535053925 0.9948545435765542 0.3198070138217295 1.0 0.7186547502500417 4 P00533 1 +Positive regulation of morphogenesis of an epithelium 0.7974751544453405 0.9947767919791664 0.3198448361126971 1.0 0.7186547502500417 2 P35222 1 +Protein localization to phagophore assembly site 0.555303048201921 0.9932260460407012 0.3205998080507617 1.0 0.7193370986127235 8 P53365,O95140,Q5MNZ6,Q7Z3C6 4 +Polarized epithelial cell differentiation 0.5552414465439062 0.9929391930551552 0.3207395883559951 1.0 0.7194098799069208 8 Q14517 1 +Regulation of small molecule metabolic process 0.3905276267138541 0.992353462000398 0.3210251323222612 1.0 0.7198094469132804 64 P01130,Q9NPF0,Q2T9J0,Q9NRA0,P31751,Q92520,O75844,Q9H2C2,Q06481,P34913,P05067 11 +Positive regulation of glycoprotein metabolic process 0.5660294419723819 0.991228092772783 0.3215742158836994 1.0 0.7199567216474732 7 Q92542,Q9H0U4,P35610 3 +Regulation of dendrite development 0.4402780962512329 0.983678527111248 0.325273600928794 1.0 0.7228549225634097 25 Q8WWV3,P46934,Q9NUM4,P98155 4 +Neurotransmitter receptor localization to postsynaptic specialization membrane 0.7904352498656597 0.9821492880287188 0.3260263066389197 1.0 0.7228549225634097 3 Q12959,Q14118 2 +Histone lysine demethylation 0.5417465050089169 0.9821080402310884 0.3260466248587375 1.0 0.7228549225634097 9 Q8NB78 1 +Positive regulation of protein localization to cell surface 0.6523018297194303 0.9815875674973809 0.3263030748279667 1.0 0.7228549225634097 4 O94898 1 +Autonomic nervous system development 0.6522286099194519 0.9812948285857244 0.3264473722153096 1.0 0.7228549225634097 4 O14786 1 +Serotonin metabolic process 0.7939833467633781 0.9810574093246875 0.326564431787731 1.0 0.7228549225634097 2 Q04656 1 +Positive regulation of dephosphorylation 0.4713956772237779 0.980181729487132 0.3269964215191365 1.0 0.7230386067374639 17 P17301,Q86XL3,P42345,P04062,P0DP25 5 +Fatty acyl coa biosynthetic process 0.5019951915162795 0.9772769477950548 0.3284320623360663 1.0 0.7245546180663116 13 Q9UMR5 1 +Rna polyadenylation 0.4182821724308672 0.9761421664448676 0.3289940180993351 1.0 0.7245546180663116 33 Q5KU26 1 +Positive regulation of bmp signaling pathway 0.5515492940385107 0.9757505751414632 0.3291880828151821 1.0 0.7245546180663116 8 Q04721 1 +Vitamin metabolic process 0.4148061899696505 0.975502113793325 0.3293112536826734 1.0 0.7245546180663116 34 Q99538,Q9NPF0,Q9H2D1,Q8N0U8,P04062,P11166,P41440,P98164 8 +Phosphatidylethanolamine biosynthetic process 0.788493746692279 0.9750160887683712 0.329552279391591 1.0 0.7245546180663116 3 P35790 1 +Hormone biosynthetic process 0.5300460409233319 0.9731204856376436 0.3304934236840244 1.0 0.7245546180663116 10 Q53GQ0,P56937,Q9UBM7,P30536 4 +Homologous chromosome segregation 0.5012095956671313 0.9730062681915276 0.3305501867877991 1.0 0.7245546180663116 13 Q92791,Q96KQ7,Q9BTX1 3 +Regulation of bone mineralization 0.5887675025948751 0.9729650500922704 0.3305706726615471 1.0 0.7245546180663116 6 O75844,Q4KMQ2 2 +Adiponectin activated signaling pathway 0.787925816727871 0.972931033649556 0.3305875798472018 1.0 0.7245546180663116 3 Q06481 1 +Steroid hormone biosynthetic process 0.560927117845399 0.9681530647636784 0.3329679314152154 1.0 0.7265428706920071 7 Q53GQ0,P56937,Q9UBM7 3 +Epithelial tube formation 0.429037401522064 0.9678754872379424 0.3331065578913581 1.0 0.7265428706920071 29 O14641,P11233,O15031,P22694,O00592,Q13308,P17612,P98164 8 +Positive regulation of protein kinase activity 0.3823789517770377 0.9677371612889968 0.3331756538992148 1.0 0.7265428706920071 67 P14174,O14641,Q8NDZ4,Q15058,P12956,Q14118,P00533,P14635,Q14012,P0DP25,O00571,Q9Y6N7,P98155 13 +Positive regulation of neuron projection arborization 0.7902229384904741 0.9663226485707406 0.3338827563789264 1.0 0.7270603807031106 2 O14641 1 +Positive regulation of excitatory postsynaptic potential 0.7902229384904685 0.9663226485707176 0.3338827563789379 1.0 0.7270603807031106 2 Q9UQB8 1 +Positive regulation of neurotransmitter uptake 0.7899543378995585 0.96527179609944 0.334408694464678 1.0 0.7274284551451711 2 P05556 1 +Positive regulation of lipid catabolic process 0.6479791604249363 0.9643229675897766 0.3348840294209765 1.0 0.727659532416066 4 P31751 1 +Copper ion transport 0.7854845122504326 0.9639763804061572 0.335057767826119 1.0 0.727659532416066 3 Q04656 1 +Folic acid containing compound metabolic process 0.4909716267444654 0.9639763336627885 0.3350577912617098 1.0 0.727659532416066 14 Q92820,Q9H2D1 2 +Inositol lipid mediated signaling 0.4453150248808806 0.9571006441022474 0.3385164585527975 1.0 0.7327962872160365 22 Q8NDZ4,Q07021,P00533,P46934,Q05086 5 +Lens fiber cell development 0.7834497581945153 0.956523273368824 0.3388079319276205 1.0 0.7329504649092219 3 P29317,P08670 2 +Negative regulation of lipid metabolic process 0.4705995175943391 0.9536244270747384 0.3402737865247247 1.0 0.7335453130496509 16 Q92673 1 +Negative regulation of lipase activity 0.7815690488984376 0.9496429762555422 0.3422936936125813 1.0 0.7357370252213479 3 Q99523,P04083 2 +Positive regulation of collagen metabolic process 0.7813809504117031 0.948955305205502 0.3426433443680414 1.0 0.7357370252213479 3 P17301 1 +Response to uv a 0.7812803125333195 0.9485874168222588 0.3428304932920181 1.0 0.7357370252213479 3 P00533 1 +Intracellular protein transmembrane transport 0.4365402905719261 0.9444894655279502 0.3449195825906652 1.0 0.7383107769155665 24 Q9Y5Y5,Q99595,O95831,Q3ZCQ8,P31751,Q15629 6 +Establishment of endothelial intestinal barrier 0.5442194442221027 0.9416565987889176 0.3463684822595292 1.0 0.7404662099213285 8 Q9Y624,Q9H0U4 2 +Morphogenesis of a polarized epithelium 0.4683465647767598 0.9401308956168468 0.3471504228713318 1.0 0.7405067728983002 16 Q14517,O14641,Q8TAA9 3 +Alcohol catabolic process 0.4950543556937749 0.93954324824471 0.347451898399381 1.0 0.7405067728983002 13 Q8WTV0,Q9NX62 2 +Nonribosomal peptide biosynthetic process 0.5808071777292192 0.9386913718941634 0.347889224599754 1.0 0.7405067728983002 6 Q9UJ14 1 +Cell communication by electrical coupling involved in cardiac conduction 0.5543229879397787 0.9383232000776812 0.3480783405661252 1.0 0.7405067728983002 7 P0DP25,P05026,P17612 3 +Regulation of positive chemotaxis 0.7829707225356082 0.9380290722998073 0.3482294698578747 1.0 0.7405067728983002 2 P17301 1 +Negative regulation of leukocyte migration 0.5541341401132664 0.9374709092697 0.348516380900453 1.0 0.7405503990967995 7 O94813 1 +Renal water homeostasis 0.5983496215527607 0.9354837185110972 0.349539070183487 1.0 0.7413359121285665 5 P17612,P22694 2 +Arachidonic acid secretion 0.7821649207628455 0.9348958157217708 0.3498419936855654 1.0 0.7417402852517114 2 P14174 1 +Fibroblast migration 0.4764505868961472 0.932424206170166 0.3511173399037512 1.0 0.7433852166948701 15 P05556,Q06481,O95470 3 +Organophosphate catabolic process 0.4039193891492504 0.9323323678487774 0.3511647850233925 1.0 0.7433852166948701 48 Q92485,P01130,Q8NCC3,Q9H773,Q8NHP8,P13051,Q9NX62,Q8WTV0 8 +Positive regulation of endothelial cell migration 0.4329007842087345 0.9312350370413582 0.3517319976169122 1.0 0.7433977264984272 25 Q99538,Q8WTV0,O14786 3 +Regulation of cell maturation 0.7756582482536235 0.9280747670027568 0.3533687875267706 1.0 0.7437988758223695 3 O14965,Q15058 2 +Animal organ morphogenesis 0.4417936388956082 0.9257009809427992 0.3546013979588489 1.0 0.7439311945833281 132 Q9P273,Q7Z3C6,Q9NX62,P04062,Q14118,P00533,Q8TAA9,P16870,P19021,P17301,Q14517,P54802,P10253,P98164,Q92896,P29317,O75844,O14786,P53701,Q04721,O94813,O75882,Q9Y6N7 23 +Cellular carbohydrate biosynthetic process 0.4545511038447019 0.9251102516407652 0.3549085610188429 1.0 0.7439311945833281 19 P31751,Q7LGA3,O43505,Q8N6G5 4 +Lens fiber cell differentiation 0.5775291812121913 0.9246039382083427 0.3551719637694561 1.0 0.7439311945833281 6 P29317,P08670 2 +Positive regulation of protein catabolic process 0.3728070186252635 0.9244484630474262 0.3552528723823109 1.0 0.7439311945833281 81 O14965,P04062,Q9H270,P46379,Q9Y4X5,P53634,Q13190,Q96J02,Q92673,Q14145,P98164,P01130,O00308,P46934,O43847,Q9UKS6,Q06787,Q13049,Q07954 19 +Sperm capacitation 0.7734734298783421 0.9201246385945068 0.357507630248369 1.0 0.7457025766746433 3 P17612 1 +Regulation of cytoplasmic translation 0.4914083475104723 0.919723188354694 0.3577174318296516 1.0 0.7457025766746433 13 Q06787,P67809,O60506 3 +Tube formation 0.4170718747842029 0.9181244112726216 0.3585537360510913 1.0 0.7465135566991035 31 O14641,P11233,O15031,P22694,O00592,Q13308,P17612,P98164 8 +Response to dopamine 0.4908392571852565 0.9166298578736272 0.3593366328933527 1.0 0.7469307247392281 13 Q92542,P08754,P09471 3 +Regulation of superoxide metabolic process 0.5937603925212513 0.9164409813825484 0.3594356490835877 1.0 0.7469307247392281 5 P04899,P08754 2 +Regulation of action potential 0.4984703572413506 0.915679104564979 0.3598352276981313 1.0 0.7469307247392281 12 Q14126,Q12959,P04062,Q06787,P78310,P0DP25 6 +Myeloid cell activation involved in immune response 0.4822276129684891 0.9149340949770952 0.3602262296866707 1.0 0.7469307247392281 14 P51809,Q9NRA0,O00161 3 +Response to mechanical stimulus 0.4219090439237295 0.9142429326868468 0.360589209502286 1.0 0.7469307247392281 29 P17301,Q14118,Q96QD8,Q9Y624 4 +Purinergic nucleotide receptor signaling pathway 0.7717986034792459 0.9140386682323084 0.3606965276156244 1.0 0.7469307247392281 3 P04899 1 +Phospholipid catabolic process 0.4565988253373618 0.9125789240104908 0.3614640431065785 1.0 0.7469307247392281 18 Q92485,P01130,Q8NCC3,Q8NHP8,Q8WTV0 5 +Establishment of lymphocyte polarity 0.6347934740955484 0.9119054594004932 0.361818487397068 1.0 0.7469307247392281 4 Q14254,Q96L92 2 +Response to cold 0.4728770955988719 0.9117221081876968 0.3619150228151833 1.0 0.7469307247392281 15 Q14011,Q06481,P17252,P17612 4 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.4562114476042675 0.910165924610892 0.3627350117183205 1.0 0.7469307247392281 18 O95831,Q9Y6N7 2 +Positive regulation of mitochondrion organization 0.4298881143752031 0.909790477791108 0.3629330173195066 1.0 0.7469307247392281 25 O14965,P21796,P11233,Q8N2A8,P27544,O00429,Q9GZY8,Q9Y3D6 8 +Regulation of oocyte maturation 0.7754499059897983 0.9088711717887318 0.3634181325284498 1.0 0.7469307247392281 2 O14965 1 +Positive regulation of cell maturation 0.7754499059897983 0.9088711717887318 0.3634181325284498 1.0 0.7469307247392281 2 O14965 1 +Neutrophil degranulation 0.5917637895314645 0.9081693176369828 0.3637887719749126 1.0 0.7469307247392281 5 Q15833,P12429,P51809 3 +Neutrophil activation involved in immune response 0.5917637895314645 0.9081693176369828 0.3637887719749126 1.0 0.7469307247392281 5 Q15833,P12429,P51809 3 +Negative regulation of anoikis 0.7697284933460848 0.906526608992654 0.3646571874299802 1.0 0.7469307247392281 3 P05556 1 +Positive regulation of muscle tissue development 0.5912769897610659 0.9061538295697972 0.3648544368925024 1.0 0.7469307247392281 5 P41440 1 +Positive regulation of filopodium assembly 0.536195073944991 0.9043922898028104 0.3657874250808355 1.0 0.7469553086202801 8 P11233,O14786 2 +Regulation of fatty acid transport 0.5900019246169229 0.9008770943553538 0.367653671191535 1.0 0.7498523750230273 5 P31751,P14174 2 +Primary amino compound metabolic process 0.768034905939798 0.9003895116217866 0.3679130004333126 1.0 0.7500436713743773 3 Q04656 1 +Pointed end actin filament capping 0.7730325006715024 0.8995411341439368 0.36836449598756 1.0 0.7500436713743773 2 P28289 1 +Cell cell junction maintenance 0.5893385481401148 0.8981331639922895 0.3691145602293599 1.0 0.7500927176037508 5 Q6IQ23,Q96J84 2 +Biological adhesion 0.5365923686437654 0.8965342298254376 0.3699675071213959 1.0 0.7511427545372904 219 Q53GQ0,Q9P273,Q9UM22,P19022,Q13740,P23458,O75955,Q14118,P00533,Q13308,P46108,Q9Y2S7,Q08380,P05067,Q8WTV0,P51805,P07947,Q9Y624,P48960,P17301,Q14517,P35613,P06756,O15031,Q07021,Q5SZK8,Q14168,P10644,Q96J02,Q9BQT9,O60716,Q5ZPR3,Q13641,P13591,P04439,Q9BY67,Q14574,P29317,P14543,Q08722,P98194,P02786,P10586,O14936,Q92692,O95819,P07942,P61225,P31949,O14786,P41440,Q14254,O60245,P05556,Q14126,P17252,Q92859,Q96J84,Q14185,Q08431,Q15058,Q9UQB8,O00192,Q6IQ23,O00592,Q15375,Q12959,P43121,Q9H3S7,P30825,P78310,O75882,Q92544,Q9HCL2,P05026,Q9Y6N7 76 +Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.5339667039051071 0.8940578065828698 0.3712909629861891 1.0 0.7526896654366121 8 P14174,Q96K76 2 +Cyclic nucleotide mediated signaling 0.5880883746827579 0.892964693984659 0.3718760800642067 1.0 0.7532471710633933 5 O60291 1 +Positive regulation of cytokine production involved in immune response 0.478263655922888 0.892704316697849 0.3720155380811447 1.0 0.7532471710633933 14 P04439,P14174 2 +Regulation of systemic arterial blood pressure mediated by a chemical signal 0.5877693813902809 0.8916464695473915 0.3725824541712308 1.0 0.7534844924126702 5 P42892 1 +Response to ether 0.6295505566872523 0.8911784971764191 0.372833418244757 1.0 0.7535805591760636 4 Q14103 1 +Negative regulation of mrna splicing via spliceosome 0.4601247204183847 0.890875276966985 0.3729960849729103 1.0 0.7536387583625098 16 P38159,O75494,Q07021,P61978,P22626,Q16629,Q13242 7 +Negative regulation of cell activation 0.444647589893793 0.8891035376894327 0.3739474378315992 1.0 0.7537826859727139 20 P01130,P10644 2 +Regulation of oligodendrocyte differentiation 0.522253265752557 0.8888277868188865 0.3740956398730144 1.0 0.7537826859727139 9 Q9Y2Y6,Q14118,P42345 3 +Epithelial cell differentiation involved in kidney development 0.5327997326802025 0.8886484725145386 0.3741920316668485 1.0 0.7537826859727139 8 O00592 1 +Cell differentiation involved in kidney development 0.5327997326802025 0.8886484725145386 0.3741920316668485 1.0 0.7537826859727139 8 O00592 1 +Dendritic spine maintenance 0.6287942992527045 0.8881947020770354 0.3744360281014884 1.0 0.7539511759671428 4 Q13614 1 +Respiratory chain complex iv assembly 0.5679091020594952 0.8833648596946777 0.37703917058307 1.0 0.7565618327089028 6 Q9Y2R0 1 +Regulation of collateral sprouting 0.7631667187368587 0.8827931283883488 0.3773480538801892 1.0 0.7567655091721576 3 Q15375 1 +Regulation of lipopolysaccharide mediated signaling pathway 0.627330586876068 0.8824240632153707 0.3775475276859752 1.0 0.7569020432400257 4 P14174,Q9UBC1 2 +Axon extension 0.412394858021284 0.8817965379379678 0.3778868441877709 1.0 0.7572213682008279 31 O94813,O14786,Q92581,P51805,P05556 5 +Positive regulation of protein targeting to membrane 0.5115318403548353 0.8816929466955317 0.3779428762768413 1.0 0.7572213682008279 10 P31751,P27105 2 +Positive regulation of pathway restricted smad protein phosphorylation 0.7620094169246778 0.8786199880618516 0.3796073544703233 1.0 0.7588342978653508 3 O00560 1 +Regulation of synaptic vesicle exocytosis 0.5011171204184862 0.8774423717927635 0.3802464071047617 1.0 0.7594803034531618 11 Q4J6C6,P0DP25,O14936,Q06787 4 +Head morphogenesis 0.5661501691853806 0.8758433545723899 0.3811151973750979 1.0 0.7597685145570988 6 O75787,O95470 2 +Regulation of b cell activation 0.4504126611082349 0.8740400832119447 0.38209642535374 1.0 0.7602708720830762 18 P02786,Q9NPF0 2 +Cellular response to peptide 0.3754139100670519 0.8732308706098466 0.3825372516211323 1.0 0.7602708720830762 86 Q99538,Q07954,P62993,O14654,Q9UQB8,P33527,P31751,Q8WWQ0,Q92673,O00459,Q06481,P04899,P05067,Q15043,O43865,P08670 16 +Protein deglycosylation 0.5654237246465939 0.8727387760588463 0.3828054771812952 1.0 0.7602708720830762 6 P33908,O00754 2 +Retina development in camera type eye 0.4537778639264658 0.8726123916451908 0.3828743840231481 1.0 0.7602708720830762 17 P54802,O14786 2 +Muscle cell differentiation 0.3672461995995821 0.8720184730348401 0.3831982998950509 1.0 0.7602708720830762 70 Q9H4M9,Q99523,Q8IV08,O75844,P10644,O75955,P67809,P78310,P41440,P05556,Q13049 11 +Positive regulation of secretion 0.3924330251143605 0.8716843624512561 0.3833805934315364 1.0 0.760407439235915 54 Q8IWT6,P14174,Q9NRA0,P51151,O00429,O00213,P04899,P51809,P55011,Q92783,P11279,O00560,Q9H3S7,Q9NQ11,O14964 15 +Innate immune response 0.4414061590750527 0.867514310549832 0.385660274269475 1.0 0.7608758192976219 136 Q92485,P14174,P01889,O43823,O00584,Q5KU26,P23458,O43405,Q07021,Q96J02,Q06481,P51809,P04439,Q9BY67,Q08722,O60506,Q13137,P11279,P10321,Q9UNK0,Q13049,Q92692 22 +Dna modification 0.4044777693377373 0.8655786106059166 0.386721289499029 1.0 0.7612935630180634 33 Q9H9B1,Q8NB78,Q96KQ7,P13051 4 +Late endosome to lysosome transport 0.5635827046268743 0.8648757971052478 0.3871069629968651 1.0 0.7614883668931582 6 Q9Y3E7,Q9NZZ3 2 +Sensory organ development 0.3631437229348793 0.8635290495293914 0.387846654695229 1.0 0.7618937004986505 78 P42892,Q14517,Q04721,O14641,Q9P273,P54802,Q15293,Q16706,P29317,P08670,Q5SZK8,P00533,Q13308,O14786,Q9Y6M7 15 +Cyclic nucleotide catabolic process 0.7636314799892552 0.8634657833607278 0.3878814243660691 1.0 0.7618937004986505 2 P09543 1 +Sensory perception of light stimulus 0.4444424963907761 0.8608425178636346 0.3893247841780725 1.0 0.7632921418334094 19 Q6P4Q7,Q9H6K4,P50897 3 +Multicellular organism aging 0.4725674572488012 0.8607723045212616 0.3893634614563495 1.0 0.7632921418334094 14 O75844,P04062,Q14344 3 +Positive regulation of receptor clustering 0.7625570776255702 0.859364888212313 0.3901392349035768 1.0 0.7641909176586349 2 Q15334 1 +Cardiolipin biosynthetic process 0.7620198764437249 0.8573161945960717 0.3912701608156843 1.0 0.7645999645489043 2 Q32NB8 1 +Regulation of response to tumor cell 0.6202495080847932 0.854592685580893 0.3927766783083128 1.0 0.7654451419541994 4 Q92692 1 +Negative regulation of epithelial cell migration 0.496560642526672 0.8542432586971913 0.3929702190318034 1.0 0.7654451419541994 11 P67870,O94813 2 +Cytokine production involved in immune response 0.4629340577049562 0.854131471329315 0.393032148070084 1.0 0.7654451419541994 15 P04439,P14174 2 +Cellular modified amino acid catabolic process 0.5058790593562815 0.8538434680141825 0.3931917261510356 1.0 0.7654451419541994 10 Q8WUX2,Q9UHG3,Q9UJ14 3 +Negative regulation of mitochondrial fusion 0.7548803889179418 0.8530019643703982 0.3936582148602503 1.0 0.7657259838474425 3 P02786 1 +Vesicle mediated transport between endosomal compartments 0.424498993339053 0.8498374619473648 0.395415458731762 1.0 0.7670258768220749 23 Q13614,Q96ED9,Q92673,Q9H270,Q9Y3E7,Q9UNK0,A4D1P6,Q9H3S7 8 +I kappab kinase nf kappab signaling 0.3765792424986431 0.8486361134735735 0.3960838053996429 1.0 0.7676557732181629 64 Q9NRA0,Q8TB61,Q13501,Q8IUH4,Q8WVQ1,P02786,O43657,Q13049,Q9UBC1 9 +Estrogen biosynthetic process 0.7533401713597027 0.8474879526361458 0.396723199298969 1.0 0.767784834450387 3 P56937 1 +Cellular response to xenobiotic stimulus 0.4105647367407565 0.8471757220663143 0.3968971835781616 1.0 0.7678998049482793 30 P02786,O43169,Q8NC42 3 +Body fluid secretion 0.4495750050667436 0.8469446869160683 0.3970259529534918 1.0 0.7679272544572302 17 P19021,Q04656 2 +Viral process 0.4636002532287415 0.845265728571578 0.3979624912832282 1.0 0.7692548623587843 156 P07711,P07858,Q14118,P00533,Q9Y3E7,Q8WTV0,Q9Y624,P17301,P35613,P06756,Q96J02,P11717,Q14108,P56545,P01130,P13591,P29317,P02786,Q13137,P11279,O14786,P46934,P05556,P27105,Q06787,P08195,P78310,Q13049,O15118,Q92692 30 +Cellular component morphogenesis 0.4774304079820815 0.8441526804343406 0.398584092907942 1.0 0.7693099439588376 168 O14965,Q9P265,Q9Y6W5,P19022,Q13740,Q13614,O75955,Q14118,P05067,P51805,Q9ULH0,P98155,P35613,O15031,P33176,P10644,Q06481,Q9P2X3,Q13641,P98164,Q8N0X7,P13591,Q9BVA1,Q16527,Q9NUM4,O14641,P29317,O00429,Q04656,Q9Y4F1,Q92692,O95819,O14786,P46934,P05556,P42892,Q04721,Q92859,Q9UQB8,O94813,Q15375,O15228,O00213,P41440,Q92581,Q9Y3D6,Q05086,Q9Y6N7 48 +Response to auditory stimulus 0.7585280687617537 0.8440286600166217 0.3986533905117466 1.0 0.7693099439588376 2 Q8N2K0 1 +Positive regulation of epithelial cell migration 0.3959538688046988 0.8424151709876462 0.3995556040480896 1.0 0.7699483703674543 38 Q99538,P17301,Q13685,O14786,Q8WTV0 5 +Sulfur compound catabolic process 0.4941583551648472 0.8420223563938708 0.3997754396826563 1.0 0.7699483703674543 11 P16278,P15586 2 +Spindle assembly involved in female meiosis 0.7579908675799174 0.8419889469256193 0.399794140387756 1.0 0.7699483703674543 2 O14965 1 +Renal tubule development 0.5122629518858001 0.8411836645316727 0.4002450504496508 1.0 0.7705953255138064 9 Q04721,Q12959,Q9Y5V3,P35222,P35610 5 +Regulation of alpha beta t cell activation 0.5031231129608539 0.8402817629331524 0.4007504242281863 1.0 0.7709278278266622 10 P04439 1 +T cell extravasation 0.7513178565152163 0.8402596144737208 0.4007628397714251 1.0 0.7709278278266622 3 Q9Y624 1 +Regulation of mitochondrial gene expression 0.4840065323523226 0.8394887454527332 0.4011951021657478 1.0 0.7710953755993237 12 Q07021,Q9Y2R0 2 +Carnitine metabolic process 0.5216055340366901 0.8368689678082597 0.4026662252472186 1.0 0.772151370989087 8 P23786 1 +Positive regulation of protein dephosphorylation 0.4597992369782767 0.8359848934618781 0.4031634015980321 1.0 0.7726626015184476 15 P04062,Q86XL3,P42345,P0DP25 4 +Protein oxidation 0.7553048616706965 0.8318088622455178 0.4055168408042382 1.0 0.7735644708698072 2 P30048 1 +Lens morphogenesis in camera type eye 0.748802557978316 0.8312879473504886 0.4058109817171831 1.0 0.7735644708698072 3 P29317 1 +Outflow tract morphogenesis 0.4823858703873522 0.8309648413530868 0.4059934914567402 1.0 0.7735644708698072 12 P98164,Q9Y6N7 2 +Regulation of platelet activation 0.6141823628211682 0.830866846898825 0.4060488543163694 1.0 0.7735644708698072 4 Q9Y624 1 +Negative regulation of protein catabolic process 0.3929503468198205 0.8287818320889233 0.4072278704811398 1.0 0.7746923610458698 47 P00533,O94898,Q16850,O00560,Q8N9N5,P10619,Q9NQ11,Q9H2J4 8 +Positive regulation of lipid transport 0.5006699745161758 0.8282201320924398 0.4075458444745949 1.0 0.7748573757925491 10 Q07954,Q9NV96 2 +Neurotransmitter metabolic process 0.6129111871605925 0.8259108378075853 0.4088546722287123 1.0 0.7764647246463106 4 P21964 1 +Regulation of protein binding 0.3817967975616734 0.8251228814305167 0.4093018303744469 1.0 0.7765330068110287 59 O14965,Q07954,P17252,O75955,Q92673,P10586,Q96D46,P46108,Q9Y2S7,Q14012,P17612,P05067,O14786,P41440 14 +Oligodendrocyte differentiation 0.4256433681808189 0.8237052695738479 0.4101070445352548 1.0 0.7766277098257298 22 Q92542,P42345,Q9Y2Y6,Q14118,P35222 5 +Locomotory exploration behavior 0.7466185121098023 0.8235150302637992 0.4102151734979236 1.0 0.7766277098257298 3 Q05086 1 +Adhesion of symbiont to host 0.5704428930293814 0.8204253071190114 0.4119736934676195 1.0 0.7785197249872492 5 Q8WTV0 1 +Postsynapse organization 0.3934406651042857 0.8200140361698498 0.412208105580192 1.0 0.7786411284099344 39 Q99538,Q9Y6W5,Q9UQB8,Q13614,Q12959,Q15375,Q9Y4F1,O14786,Q05086 9 +Cytokine mediated signaling pathway 0.3868827798789191 0.8191411320730535 0.4127058967362806 1.0 0.7790801282382926 54 O94813,P15260,Q06481,Q16739 4 +Regulation of protein targeting to membrane 0.4896264953279668 0.8189903915284229 0.4127918956269882 1.0 0.7790801282382926 11 P27105 1 +Behavioral response to pain 0.7448632449094998 0.8172799661954357 0.4137684528736307 1.0 0.7790801282382926 3 P42345 1 +Response to pain 0.7448632449094998 0.8172799661954357 0.4137684528736307 1.0 0.7790801282382926 3 P42345 1 +Rap protein signal transduction 0.5696150820178489 0.8170431564777075 0.4139037656658506 1.0 0.7790801282382926 5 P61225 1 +Cobalt ion transport 0.7512758528068944 0.8165978180395154 0.4141583024393749 1.0 0.7790801282382926 2 Q8N4V1 1 +Regulation of alternative mrna splicing via spliceosome 0.401065631176009 0.814871124112613 0.4151460835017275 1.0 0.7793582777671086 32 P62995,P31483,P38159,Q9BWF3,Q92879,O75525,Q9UHX1,P51114,Q06787,Q07666,P51116,P52756,P98175 13 +Enamel mineralization 0.7439548629768897 0.8140574216191838 0.4156120563766863 1.0 0.7795779462178987 3 Q6P4Q7,P04920 2 +Amelogenesis 0.7439548629768897 0.8140574216191838 0.4156120563766863 1.0 0.7795779462178987 3 Q6P4Q7,P04920 2 +Positive regulation of smooth muscle cell proliferation 0.4973704793438397 0.8120133845412731 0.4167839514005587 1.0 0.7813387530871453 10 P17301,P04899 2 +Very low density lipoprotein particle assembly 0.7496642492613557 0.8105337712075529 0.4176334635804428 1.0 0.7820562930751964 2 P35610 1 +Tetrapyrrole catabolic process 0.6089009084576893 0.8103113955222464 0.4177612275396165 1.0 0.7820770242934386 4 P30519 1 +Pallium development 0.3915873947513171 0.8095810406664494 0.4181810083611073 1.0 0.7824868654905478 45 P62995,P19022,Q15058,Q96QD8,O94813,P00533,P07942,P11166,P18887,P51805,Q9Y6N7 11 +Type b pancreatic cell proliferation 0.7493956486704263 0.8095242491334694 0.4182136604278039 1.0 0.7824868654905478 2 O00255 1 +Sulfur compound biosynthetic process 0.3897177315052127 0.8092391089557416 0.4183776233316252 1.0 0.7825408742039796 49 Q9UMR5,O43505,P50897,Q9UJ14,Q9P2E5,Q8NCH0,Q8N6G5 7 +Positive regulation of coagulation 0.7425467977835238 0.8090679697947388 0.4184760509022773 1.0 0.7825408742039796 3 Q9Y6X5 1 +Tooth mineralization 0.6076741208987918 0.8055504738736422 0.4205020920762168 1.0 0.7840687533280656 4 Q6P4Q7,P04920 2 +Nephron morphogenesis 0.5659367264702385 0.802040007629177 0.4225298159771569 1.0 0.7868282374767729 5 Q12959,Q9Y5V3,P35222 3 +Regulation of protein kinase a signaling 0.6066455426231059 0.8015628812156811 0.4228058564068591 1.0 0.7869049846261509 4 P14174 1 +Hemostasis 0.4045182073309408 0.8008203918354031 0.4232356319964685 1.0 0.787049169156585 30 P17301,Q86YV9,Q4KMQ2,Q14344,Q9UNN8,Q9Y6X5,P61225,Q9Y624 8 +Folic acid metabolic process 0.5234862000200546 0.7999117209026051 0.42376194639047 1.0 0.7873665949904678 7 Q9H2D1,P41440 2 +Negative regulation of phosphorylation 0.3674897368880835 0.7993572777067028 0.4240832753312331 1.0 0.7873665949904678 85 Q86XL3,Q16625,O94813,Q9BRG1,P04062,Q92673,P10644,Q9H3E2,Q6YHK3,Q07954 10 +Phagosome lysosome fusion 0.745903840988446 0.7964309190894531 0.4257816129120002 1.0 0.7877586699085669 2 P51149 1 +Protein demethylation 0.4941306872435028 0.7961197790138732 0.4259624189140703 1.0 0.7877586699085669 10 Q8NB78 1 +Cellular response to extracellular stimulus 0.3842748830882987 0.794408047805579 0.4269579205794103 1.0 0.7883607008054273 54 Q9H773,O95831,Q96QD8,P04062,P13473,P11166,Q96KQ7 7 +Cell growth 0.4037486927706638 0.7929352823811363 0.4278155296881809 1.0 0.7885522384698338 112 O14965,Q9P265,Q13740,P00533,P05067,P51805,Q9Y2Q5,P50897,Q9NRA0,Q96J02,Q9BQT9,Q9P2X3,Q8N0X7,P22413,P02786,O14786,O00571,P05556,O94813,Q96K76,Q15375,O00560,Q13049,Q92581,Q6PJG6 25 +Detection of calcium ion 0.7437550362610854 0.788402106062904 0.4304615393103419 1.0 0.789532905434568 2 P0DP25 1 +Smoothened signaling pathway 0.411014403758549 0.7869896885729056 0.431287902397391 1.0 0.7903996504969414 26 Q6NUS6,P17252,Q7Z4L5,P22413,A0AVF1,Q8WWQ0,O60291,P22694,Q15019,P17612,Q6PHR2 11 +Regulation of trans synaptic signaling 0.3734267230325562 0.7835027900009384 0.4333319159541116 1.0 0.7926672241036038 62 Q13501,Q13614,O75955,P55011,P05067,Q99538,P33176,Q14168,P04899,Q9BQT9,P17612,P0DP25,Q4J6C6,O14936,P05556,Q9UQB8,Q92542,Q06787,P41440 19 +Mannose metabolic process 0.6010869500677709 0.7800804047649906 0.4353435496020499 1.0 0.7939244814783506 4 O00754 1 +Guanine nucleotide transport 0.6008919211984827 0.779328782089228 0.4357860641978188 1.0 0.7942956997313622 4 P41440 1 +Guanine nucleotide transmembrane transport 0.6008919211984827 0.779328782089228 0.4357860641978188 1.0 0.7942956997313622 4 P41440 1 +Response to acetylcholine 0.5599953371811112 0.7778984382292994 0.4366288890698313 1.0 0.7954027764463196 5 P04899 1 +Negative regulation of glial cell proliferation 0.7330304918121824 0.7755374644339875 0.4380221365325187 1.0 0.796880710069061 3 Q96G23 1 +Positive regulation of endocytic recycling 0.7328780165713127 0.775003014826423 0.4383378781196581 1.0 0.7972158640862818 3 Q92673 1 +Telencephalon development 0.3864220305815726 0.7742827697084447 0.4387635907019678 1.0 0.7975572511213963 48 P62995,P19022,Q15058,Q96QD8,O94813,P00533,P07942,P11166,P18887,P51805,Q9Y6N7 11 +Inflammasome complex assembly 0.5991032981973059 0.7724424771343137 0.4398524038888243 1.0 0.798669956885099 4 O00571,Q8IXJ6 2 +Ribonucleoside diphosphate catabolic process 0.7315644532666135 0.7704025432249751 0.4410611452761557 1.0 0.8004310305011632 3 Q9NQZ7 1 +Nucleoside diphosphate catabolic process 0.7315644532666135 0.7704025432249751 0.4410611452761557 1.0 0.8004310305011632 3 Q9NQZ7 1 +Regulation of phosphatidylinositol 3 kinase activity 0.5984548741985138 0.7699491009130103 0.4413300860814269 1.0 0.8004855850927531 4 O00459 1 +Energy homeostasis 0.4885322792728551 0.7687075237632836 0.4420669574480036 1.0 0.8016051809568507 10 Q13501 1 +Positive regulation of response to biotic stimulus 0.38708592796568 0.767340318984142 0.4428792023278598 1.0 0.8020575689048084 38 P14174,O43405,Q6PIJ6,Q9NUD5,Q9BY67,P11279,P12956,Q92692 8 +Male sex differentiation 0.4045342941548557 0.7671015699903948 0.443021128558805 1.0 0.8020575689048084 28 Q13772,P98164 2 +Response to potassium ion 0.5976884311074173 0.7670040576349103 0.4430791030281829 1.0 0.8020575689048084 4 Q14168,P55011 2 +Cellular response to potassium ion 0.5976884311074173 0.7670040576349103 0.4430791030281829 1.0 0.8020575689048084 4 Q14168,P55011 2 +Execution phase of apoptosis 0.447773674030522 0.7664697685411047 0.4433968333448397 1.0 0.8020575689048084 15 O00115 1 +Ear morphogenesis 0.4363665977552428 0.766354506667207 0.443465394187748 1.0 0.8020575689048084 17 O14641,Q96JA1,P54802,Q8N584,Q13308 5 +Negative regulation of multicellular organismal process 0.4194232595173583 0.765929327216604 0.4437183546604941 1.0 0.8020575689048084 126 Q9P265,P15260,O43823,P04062,P00533,P51805,Q99538,Q9UIQ6,P53634,Q07021,Q9Y2Y6,Q96J02,Q92673,Q06481,Q16850,P04899,P67870,P01130,Q96G23,P31483,P29317,O14786,O43847,O94813,Q15375,Q9UNN8,Q9Y6N7 27 +Cell surface receptor signaling pathway involved in heart development 0.7302685787774286 0.7658707048296275 0.4437532385074445 1.0 0.8020575689048084 3 Q04721 1 +Otolith development 0.7302525523911828 0.7658147003890569 0.4437865659816564 1.0 0.8020575689048084 3 Q8N584,Q96JA1 2 +Long chain fatty acid import across plasma membrane 0.730153830392779 0.7654697375840631 0.4439918801308324 1.0 0.8020575689048084 3 P11166 1 +Catechol containing compound metabolic process 0.5155803661836235 0.7647603884699194 0.4444142392383099 1.0 0.8025227849067574 7 P21964 1 +Regulation of lipophagy 0.7298910622210044 0.7645517408975357 0.4445385153466104 1.0 0.8025227849067574 3 O15269 1 +Regulation of protein dephosphorylation 0.4077121689727517 0.7631035131707337 0.4454016650283234 1.0 0.8033051558180365 26 O75663,Q86XL3,P42345,P04062,P67870,P04899,P0DP25 7 +Nadp metabolic process 0.4469729882014714 0.761848779849622 0.4461502629496685 1.0 0.8033573724239398 15 Q13423 1 +Positive regulation of biomineralization 0.7289091886082704 0.761123962451502 0.44658302915899 1.0 0.8033573724239398 3 Q4KMQ2,P04920 2 +Positive regulation by host of viral process 0.4952205419461646 0.7603297484549211 0.4470575041468407 1.0 0.8033573724239398 9 P11717 1 +Gland development 0.3679838472925808 0.7571805195943656 0.4489417193794938 1.0 0.8033573724239398 88 Q04721,P17301,Q9BY67,P29317,P31751,Q04656,O75844,Q14118,P00533,P07602,P11717,Q14103,O14786,Q8TDY2,P19021,Q05086,Q9Y6N7 17 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.4538630859466824 0.7561511703357207 0.4495585652091924 1.0 0.8033573724239398 14 Q07021,O43657 2 +Negative regulation of protein kinase b signaling 0.5038592799604119 0.7553131201121681 0.4500611282711384 1.0 0.8033573724239398 8 Q14118 1 +Negative regulation of developmental process 0.4100556340013742 0.7475317388763824 0.4547426516925734 1.0 0.8094861381812412 120 Q99523,P14174,P00533,P05067,P51805,Q99538,P06756,Q92673,O94898,Q06481,Q8N4Q0,P01130,Q96G23,P29317,P02786,P67809,O14786,P05556,Q15375,Q05086 20 +Erbb signaling pathway 0.4037287667348813 0.7468813659443609 0.4551351749395846 1.0 0.8098135211539677 27 Q99538,Q9BRG1 2 +Positive regulation of peptidase activity 0.384143820606633 0.7462451338001325 0.4555193482577886 1.0 0.8100589252080819 46 Q99538,P05067,Q92542,Q9Y6N7 4 +Regulation of gene silencing by rna 0.4226127209012496 0.7460629336547097 0.4556293989952054 1.0 0.8100589252080819 20 Q9NRA8,P51114,O75844,Q06787,P00533 5 +Sensory system development 0.3806692288359021 0.744462375606115 0.4565967950821843 1.0 0.811270339512407 52 Q04721,Q14517,Q9P273,P54802,P29317,Q5SZK8,P00533,O14786 8 +Negative regulation of leukocyte apoptotic process 0.5105801282569613 0.7426218135866577 0.4577106781070248 1.0 0.8126031694498757 7 Q9HCL2 1 +Negative regulation of lymphocyte apoptotic process 0.5105801282569613 0.7426218135866577 0.4577106781070248 1.0 0.8126031694498757 7 Q9HCL2 1 +Excitatory synapse assembly 0.7308622078968774 0.7407131602026489 0.4588673782042309 1.0 0.8140098382014588 2 O15031 1 +Regulation of fibroblast growth factor receptor signaling pathway 0.7308622078968532 0.7407131602025613 0.458867378204284 1.0 0.8140098382014588 2 P35222 1 +Positive regulation of fibroblast growth factor receptor signaling pathway 0.7308622078968532 0.7407131602025613 0.458867378204284 1.0 0.8140098382014588 2 P35222 1 +Response to calcium ion 0.4044726054374393 0.7396732871380568 0.4594982606546249 1.0 0.8142668807264137 26 Q99538,Q92542,Q14103,P46934,O43865 5 +Mapk cascade 0.4131029552836634 0.7387080366102268 0.4600843046677167 1.0 0.8146175381378259 123 Q8NC42,P14174,P19022,P04062,Q14118,P00533,P05067,P06756,Q9Y2Q5,Q96J02,Q92673,P04899,Q13641,O14641,P62993,P29317,O75787,O43164,O00459,O95819,O14786,Q7Z569,Q04721,P17252,Q12959,Q15375,O00560,Q86VI3,Q8TDY2,Q9Y6N7 30 +Pyramidal neuron development 0.5501103913647578 0.738009029155914 0.4605089623466296 1.0 0.8149458916828598 5 P51805 1 +Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.5900486726041319 0.7377802740070123 0.4606479821788376 1.0 0.8149458916828598 4 Q99729 1 +Regulation of fatty acid oxidation 0.5090526742821276 0.7358748025531671 0.4618068930129306 1.0 0.8149458916828598 7 Q2T9J0,Q06481 2 +Positive regulation of bone mineralization 0.7287134031695082 0.7328497721655042 0.4636500606329221 1.0 0.8149458916828598 2 Q4KMQ2 1 +Positive regulation of mitochondrial membrane potential 0.588394487975765 0.7314854290377615 0.4644827013860451 1.0 0.8154092053630467 4 P31751 1 +Negative regulation of cell cell adhesion 0.4274972051326465 0.73141962681329 0.4645228806440036 1.0 0.8154092053630467 18 O00592,P10644 2 +Autophagosome membrane docking 0.7200429876410483 0.73035247454643 0.4651747605569851 1.0 0.8157287568717376 3 O95721,P16615 2 +Somatic diversification of immune receptors via somatic mutation 0.5075343941110415 0.7291759921316681 0.465894014844312 1.0 0.816532868066574 7 P13051 1 +Bone morphogenesis 0.4802404456711536 0.7282480910751328 0.466461731879856 1.0 0.8173141247212536 10 O75844,Q92896,Q9NX62 3 +Epidermis morphogenesis 0.7192162077377613 0.727500145866688 0.4669196260073773 1.0 0.8176888773194259 3 Q04656 1 +Polyol catabolic process 0.4881852560076455 0.7271593741415565 0.4671283300491944 1.0 0.8178406656190442 9 P43304,Q9NX62 2 +Dopamine metabolic process 0.5308025177682621 0.7263485132590167 0.4676251459260303 1.0 0.8180526777067217 6 P21964 1 +Glomerulus development 0.4970239588616526 0.7241263840616254 0.4689881480425117 1.0 0.8195980621071484 8 O00592,P14543 2 +Positive regulation of kinase activity 0.3579785125120041 0.7229497733791951 0.4697107425557822 1.0 0.8201102657005117 83 P14174,O14641,Q8NDZ4,Q15058,P29317,P0DP25,Q12959,Q15375,Q14118,P00533,P14635,Q14012,P12956,O00571,Q9Y6N7,P98155 16 +Calcium ion regulated exocytosis 0.4872694526648984 0.7228521697231959 0.4697707117314629 1.0 0.8201102657005117 9 P04899,P51809 2 +Phototransduction visible light 0.7175394046776138 0.7217245764474474 0.470463828977417 1.0 0.8208926273904318 3 P29992 1 +Regulation of cell aging 0.4539744266076092 0.7169515718157579 0.4734039788739612 1.0 0.8235430393683632 13 O75844,P67809 2 +T cell differentiation 0.397680640078119 0.7160797608548826 0.4739421001173942 1.0 0.8240879071089098 28 Q9NQZ7,P07711,Q04656,P04062,P24390 5 +Endocrine process 0.5282332954429751 0.7156362025963804 0.4742160133733748 1.0 0.8240879071089098 6 P42892 1 +Regulation of autophagy of mitochondrion 0.4277523426404777 0.7139224797081272 0.4752751159946604 1.0 0.8252516544678735 17 P21796,P27544,O00429,P30536,Q14247,Q9NQ11 6 +Proton transporting two sector atpase complex assembly 0.5440846884723558 0.7138796378839324 0.4753016094070414 1.0 0.8252516544678735 5 Q8N511,Q92544 2 +Regulation of skeletal muscle tissue development 0.5433160024329741 0.7108124192061609 0.4772004836462491 1.0 0.8262252050094392 5 P41440 1 +Positive regulation of nlrp3 inflammasome complex assembly 0.7225355895783079 0.7103857321179629 0.4774649685170702 1.0 0.8262252050094392 2 O00571 1 +Response to yeast 0.7225355895782999 0.7103857321179334 0.4774649685170884 1.0 0.8262252050094392 2 P46108 1 +Inositol trisphosphate metabolic process 0.7225355895782981 0.7103857321179274 0.4774649685170922 1.0 0.8262252050094392 2 Q13572 1 +Positive regulation of store operated calcium channel activity 0.7225355895782977 0.710385732117926 0.4774649685170931 1.0 0.8262252050094392 2 Q13586 1 +Activation of store operated calcium channel activity 0.7225355895782977 0.710385732117926 0.4774649685170931 1.0 0.8262252050094392 2 Q13586 1 +Regulation of superoxide anion generation 0.5822090462304688 0.7080567631818107 0.4789100082224182 1.0 0.8274438966503345 4 P04899 1 +Cytoplasmic pattern recognition receptor signaling pathway 0.4166702726806484 0.7075619208687486 0.4792173470347527 1.0 0.8275482246397611 20 Q07021,O43657 2 +Mitochondrial transmembrane transport 0.3765747860196921 0.7061424005819852 0.4800995859374628 1.0 0.8282181274009977 52 P21796,Q9H2D1,Q99595,O95831,P23786 5 +Positive regulation of tor signaling 0.5258991508409318 0.7059260430204151 0.4802341309625313 1.0 0.8282370421283801 6 Q9Y2Q5,Q9H4A6,Q96EE3 3 +Neuroepithelial cell differentiation 0.5809746579929299 0.7034026180676546 0.4818048754321173 1.0 0.8301461110134282 4 P07437,P19022 2 +Regulation of amino acid transport 0.5015700060084002 0.702938510389054 0.4820940703198548 1.0 0.8301461110134282 7 P05556,Q7L0J3 2 +Roof of mouth development 0.5250776144154975 0.7025135309084 0.482358966400467 1.0 0.8301461110134282 6 Q12959,O95470 2 +Regulation of calcium ion dependent exocytosis 0.5409726530975139 0.701477801505236 0.4830048833031193 1.0 0.8301461110134282 5 P04899 1 +Negative regulation of lyase activity 0.7116296581206599 0.7014705547267153 0.4830094043006594 1.0 0.8301461110134282 3 P04899 1 +Negative regulation of adenylate cyclase activity 0.7116296581206599 0.7014705547267153 0.4830094043006594 1.0 0.8301461110134282 3 P04899 1 +Positive regulation of atpase coupled calcium transmembrane transporter activity 0.7198495836690846 0.7006870759988197 0.483498323281796 1.0 0.8303385001173347 2 P54652 1 +Protein import into peroxisome membrane 0.7109081139172437 0.699008746938197 0.4845465645001234 1.0 0.8306346985867972 3 Q9Y5Y5,P56589 2 +Protein localization to cytoplasmic stress granule 0.5006308563880689 0.6988190464771028 0.4846651239636552 1.0 0.8306346985867972 7 P67809,P31483 2 +Regulation of lymphocyte apoptotic process 0.4913063454534985 0.6981567844089087 0.4850791493555366 1.0 0.8306768081275976 8 Q9HCL2 1 +Negative regulation of transcription from rna polymerase ii promoter in response to stress 0.7106394411606612 0.6980927014359312 0.4851192221741893 1.0 0.8306768081275976 3 Q8IXJ6,Q9P2X3 2 +Pirna metabolic process 0.7101020956474964 0.6962616376571068 0.4862649930569909 1.0 0.8312464477980956 3 Q9Y2W6,Q8N2A8 2 +Cardiac muscle cell membrane repolarization 0.4996386525417744 0.6944705306192988 0.4873871755778105 1.0 0.8320093863276837 7 O75844 1 +Kidney epithelium development 0.4213538999972305 0.6933078916414839 0.488116351615095 1.0 0.8324060530596353 18 O00592,Q15375,O94813 3 +Phagolysosome assembly 0.708659709492647 0.6913533634563279 0.4893435042347005 1.0 0.8334935591650743 3 P51149 1 +Action potential 0.4016598947880938 0.6913133938187328 0.4893686165363811 1.0 0.8334935591650743 23 Q14126,Q12959,P04062,Q06787,P78310,P0DP25,P29992,P05026,P16615 9 +Regulation of filopodium assembly 0.4346826176013613 0.691087909127461 0.4895102980596171 1.0 0.8334935591650743 15 O14786,P51116,P11233,P51114 4 +Negative regulation of g protein coupled receptor signaling pathway 0.4896373649700883 0.690598210220407 0.4898180725382115 1.0 0.8334935591650743 8 O60291 1 +Regulation of cyclic nucleotide phosphodiesterase activity 0.53678913597956 0.6848740879528911 0.4934233785208963 1.0 0.8363063736062109 5 Q15043 1 +Regulation of potassium ion transmembrane transporter activity 0.4479029457418649 0.6843207404302911 0.493772652993103 1.0 0.8363063736062109 13 P05026,P05556,P46934,O00308 4 +Negative regulation of small gtpase mediated signal transduction 0.4540958791666541 0.6829798303405505 0.4946195876837109 1.0 0.8371061809737956 12 O94813 1 +Filopodium assembly 0.4251638234527329 0.6819707425112636 0.4952574512591234 1.0 0.8372535083782965 16 O14786,P51116,P11233,P51114 4 +Positive regulation of plasma membrane bounded cell projection assembly 0.3910109026043928 0.6809441101693482 0.4959068556787918 1.0 0.8379403132127013 29 P11233,Q16625,Q04656,Q06787,O14786 5 +Cellular component maintenance 0.4320401176485126 0.675924661541494 0.4990884790651435 1.0 0.8421582898206783 15 Q96J84,Q15334,Q13614,Q12959,Q6IQ23,Q14247,P56545 7 +Positive regulation of phosphatase activity 0.4859271817708337 0.6738333047245479 0.5004172983301141 1.0 0.8430834935507258 8 P17301,P0DP25,P42345 3 +Regionalization 0.3758873050431383 0.6723606314023196 0.5013541392093377 1.0 0.8433924299651058 38 Q04721,O14965,P62995,O14641,Q7Z4L5,O75787,P22694,P17612,O14786,Q9Y6N7,P98164 11 +Secondary metabolic process 0.4850306816026745 0.6697905076903177 0.5029913455209685 1.0 0.8445089259666946 8 P19021 1 +Primitive hemopoiesis 0.7022048210854692 0.669512630489126 0.5031685264356405 1.0 0.8445089259666946 3 Q13188 1 +Tight junction organization 0.4028701720102883 0.6693410845436795 0.50327792454655 1.0 0.8445089259666946 22 P17252,P29317,Q16625,Q12959,P17612,Q9Y624 6 +Regulation of anion transport 0.4380486532821512 0.6682304828362576 0.5039864802182592 1.0 0.8446405077326266 14 P14174,P55011,Q7L0J3,O43865,P05556 5 +Positive regulation of substrate adhesion dependent cell spreading 0.4227347009229833 0.6675427179198526 0.5044255329260738 1.0 0.8449537419821412 16 Q13418,Q14185,Q07021,P50570,P46108,O14786 6 +Hair follicle maturation 0.4932490498989033 0.6665612000604884 0.5050524596566193 1.0 0.8454734469132432 7 Q08J23 1 +Negative regulation of leukocyte proliferation 0.4842379784672236 0.6662185088958679 0.5052714440737069 1.0 0.8454734469132432 8 Q96J02,P10644 2 +Cardiac muscle tissue development 0.3743723426651299 0.665465696535407 0.5057526771836618 1.0 0.8454734469132432 36 Q04721,P05556,Q8NDZ4,O75844,P10644,P78310,P98164 7 +Cell communication by electrical coupling 0.4749160881502917 0.6650278413976144 0.5060326857316213 1.0 0.8454734469132432 9 P0DP25,P05026,P17612 3 +Cellular homeostasis 0.4637604835945962 0.6639533890786242 0.5067201439618427 1.0 0.8457250284534468 171 Q93050,P62995,Q15904,Q4KMQ2,Q9NWW5,P13473,Q14344,Q9Y487,P55011,P05067,Q07820,O75503,Q8IWT6,P06756,P50897,P51790,Q9H7F0,P10253,P07686,Q9Y666,P17612,Q13772,P0DP25,Q9NQ11,P02792,Q9NUM4,Q9NWR8,O75787,Q04656,P98194,P02786,O00459,Q15043,Q7L0J3,Q99808,Q8N511,Q9BXP2,Q92544,Q13049,Q9HD20,Q92581,P05026,Q05086,Q9Y6M7 44 +Camera type eye development 0.3753276110160524 0.6637604857678554 0.5068436197034702 1.0 0.8457250284534468 44 Q04721,Q14517,Q9P273,P54802,P29317,P00533,O14786 7 +Production of molecular mediator of immune response 0.3752933392376235 0.6627323310712685 0.5075019992880776 1.0 0.8463505086339824 41 P14174,P04439,P13051,P02786,Q9UQ84 5 +Negative regulation of fat cell differentiation 0.474223623523394 0.6618031408469941 0.5080973929660284 1.0 0.8468711085944596 9 Q8N4Q0,Q99523 2 +Non lytic viral release 0.4913739972510946 0.6584036073831797 0.5102788180011253 1.0 0.8480563611687132 7 Q9Y3E7,Q9NZZ3 2 +Skeletal system development 0.3649569858617555 0.6580006978129502 0.5105376827582242 1.0 0.8480563611687132 59 Q04721,Q92896,Q32P28,Q9Y6W5,Q7Z3C6,P29317,Q15904,Q04656,Q9NX62,O75844,P07686,Q15043 12 +Proton transmembrane transport 0.3744417674672832 0.6573690673756368 0.5109436361715654 1.0 0.8480563611687132 45 Q9NRA0,P51790,Q04656,Q13423,Q92581 5 +Regulation of insulin receptor signaling pathway 0.4182340273292574 0.6561856465179869 0.5117046830226708 1.0 0.8489381107632058 17 Q92673 1 +Regulation of tor signaling 0.4207068682901556 0.6555123056251413 0.512137966166242 1.0 0.8491708681954858 16 P04062 1 +Protein o linked glycosylation via threonine 0.6968190420693847 0.6514507927485395 0.5147555317514712 1.0 0.8526414863158711 3 Q10472 1 +Actin modification 0.6963158907970576 0.6497711676176325 0.5158400456729231 1.0 0.8531984171026482 3 Q13049 1 +Modulation by host of viral process 0.4412504093577398 0.648702466018139 0.5165307101399308 1.0 0.8537087100759102 13 P27105,P11717 2 +Positive regulation of cell population proliferation 0.4344511453322657 0.6481705301001902 0.5168746602856438 1.0 0.8537454541293431 147 P14174,P55209,P00533,Q99538,P17301,P06756,Q9NRA0,P43307,P04899,Q5ZPR3,Q9H2J4,P98164,Q9NPF0,P04439,P08754,Q8WWQ0,Q08722,Q04656,P02786,P14635,O14786,P05556,Q04721,P31751,O00560,P30825,Q9HCL2 27 +Keratinocyte differentiation 0.3915478909972472 0.6463000686922814 0.518085043407206 1.0 0.8537454541293431 26 Q16739,Q13510,Q6YHK3 3 +Negative regulation of intrinsic apoptotic signaling pathway 0.3714721915528706 0.6450902285136141 0.5188687157833587 1.0 0.8542024399852788 35 O95881,P14174,Q9UL15,P45880,Q96K76,Q7LG56,Q13049,Q07820 8 +Maintenance of location 0.3468641784653781 0.6437339976023018 0.5197479399232736 1.0 0.8551882231904105 80 P10253,P07686,P04062,Q92673,P24390,Q8WTV0,P17900 7 +Oogenesis 0.4066612817946106 0.6428849872001183 0.5202987315235843 1.0 0.8551882231904105 20 Q96RD7,O14965,Q8IXJ6,Q8N2A8,Q12768,P07686,P35222 7 +Establishment of planar polarity involved in neural tube closure 0.6938133438406247 0.6414372511983332 0.5212386370643296 1.0 0.8558195752488769 3 O14641 1 +Dna methylation 0.3986726121683763 0.6409834748041401 0.5215334195743897 1.0 0.8560658775379769 22 Q9H9B1,Q8NB78,Q96KQ7 3 +Negative regulation of calcium ion transport 0.461818749486353 0.639136843105379 0.5227339138113818 1.0 0.856971500437181 10 Q9UKS6,P21796,Q06787 3 +Positive regulation of production of molecular mediator of immune response 0.3900956727795152 0.6358269823548622 0.5248891986726738 1.0 0.8585289017889634 26 P02786,P14174,P04439 3 +Endothelial cell apoptotic process 0.5626788723354842 0.6353323903760686 0.5252116528401596 1.0 0.8585289017889634 4 O00255,Q4KMQ2 2 +Regulation of protein secretion 0.3716471687567079 0.6344166929818377 0.525808918340736 1.0 0.8592956280711076 46 Q8IWT6,Q32P28,O00429,Q96KC8,O00213,Q16850,P55011,Q9NQ11,P19021 9 +Regulation of store operated calcium channel activity 0.6915636754433048 0.6339744434230208 0.5260975008296633 1.0 0.8595576427499766 3 P16885,Q13586 2 +Regulation of protein lipidation 0.5082223607123193 0.6331460443332293 0.5266382764103716 1.0 0.8600218636701537 6 P04062 1 +Positive regulation of epithelial cell apoptotic process 0.5612279494790534 0.6300126798893804 0.5286862882445684 1.0 0.8620064771622701 4 P05198,Q4KMQ2 2 +Proximal tubule development 0.6903347014056762 0.6299093448852925 0.528753898480169 1.0 0.8620064771622701 3 Q04721 1 +Icosanoid transport 0.5609511134524132 0.6289990776156432 0.5293496600782239 1.0 0.8621138888030319 4 P14174,P33527 2 +Positive regulation of stress fiber assembly 0.4238327183441812 0.6289752992901125 0.5293652273489431 1.0 0.8621138888030319 15 Q08722 1 +Cellular component assembly involved in morphogenesis 0.3888479169240004 0.6268325937300098 0.5307689758501772 1.0 0.8625639369902736 26 Q16527,Q13614,P10644,Q14118,Q92692,P05556 6 +Aromatic amino acid transport 0.6890455277947289 0.6256541680678892 0.5315418010324509 1.0 0.8631152823994475 3 P30825 1 +Sodium ion export across plasma membrane 0.6883396023643146 0.6233280753982876 0.533068951903064 1.0 0.8642061237673767 3 P54709,P05026 2 +Regulation of developmental growth 0.3613952773652125 0.6225468625983096 0.5335823392746599 1.0 0.8644289022553453 59 Q99538,Q9P265,Q9HCL2,O75844,Q15375,O14786,O75882,P05067,P51805 9 +Morphogenesis of an endothelium 0.6880972565447128 0.6225301716427458 0.5335933107475923 1.0 0.8644289022553453 3 P67870 1 +Neuron development 0.5157918012970117 0.6217808912899709 0.5340859529213355 1.0 0.8645453479126282 225 O14965,Q9P265,Q9P273,Q9UL15,P08670,Q13740,Q13614,P04062,Q14118,O75955,Q13308,P05067,P51805,O75503,Q9ULH0,P98155,P35613,Q9H4M9,P50897,P54802,Q32P28,O15031,P33176,O94898,Q06481,Q14012,Q9P2X3,Q14108,Q13641,P98164,Q96G23,Q8N0X7,P13591,Q9BVA1,O14641,Q9NUM4,Q6PIJ6,Q9NQX7,P29317,Q04656,P10586,Q9Y4F1,Q9NV96,Q16739,O95819,O14786,P07942,P46934,P05556,Q13049,P42892,Q04721,Q92859,Q9UQB8,O94813,Q15375,Q06787,Q8WWV3,Q05086,P41440,Q92581,Q8NHS3,Q9Y6N7,Q9Y6M7 64 +Positive regulation of vascular associated smooth muscle cell proliferation 0.5589363973025506 0.6216360927209 0.5341811825882115 1.0 0.8645453479126282 4 P04899 1 +Necrotic cell death 0.4066459696287966 0.6212604940404011 0.5344282425055069 1.0 0.8645545450284284 19 Q13510 1 +Regulation of cysteine type endopeptidase activity 0.3659915558751754 0.6204480500540155 0.5349628461328784 1.0 0.8646660401208375 54 Q99538,Q9NR28,Q15392,O95831,Q15375,Q9Y6N7 6 +Amine transport 0.4738133068839784 0.6194980253998779 0.5355883223308822 1.0 0.8649428762076078 8 P05556,Q7L0J3 2 +Progesterone receptor signaling pathway 0.5044780525108115 0.6179203483264196 0.5366278449762487 1.0 0.865370504579119 6 P46934,Q05086 2 +Positive regulation of phosphoprotein phosphatase activity 0.5037139039045575 0.6148220337199143 0.5386722564600515 1.0 0.8676235190567807 6 Q8IV63,P0DP25,P42345 3 +Detection of abiotic stimulus 0.4486051349695764 0.6127777919674513 0.5400232770668754 1.0 0.8685471569239738 11 P17301,P19022,P29992,P35222,Q15555 5 +Regulation of embryonic development 0.4046506525385766 0.608706381709846 0.5427190762574305 1.0 0.8698376725114784 19 Q9H9B1,Q14118,Q9H0H5 3 +Skeletal muscle organ development 0.386184088006541 0.6076447479115396 0.5434231155575249 1.0 0.8698376725114784 26 O75955,Q14118,P41440,P51114 4 +Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.6824288017194998 0.6039634822200257 0.545867921151189 1.0 0.8715004085014464 3 Q13043,Q13188 2 +Neutrophil mediated immunity 0.4787549441647041 0.6039293912786056 0.5458905871216162 1.0 0.8715004085014464 7 P51809 1 +Atp synthesis coupled electron transport 0.366970584904944 0.6034404779486271 0.5462157011981117 1.0 0.8717820983521052 36 O43676,P51970,O75306,P14635,Q7KZN9,O96000,Q9Y6M9 7 +Placenta development 0.3765658479711403 0.6027525930611367 0.5466732883801906 1.0 0.8720648016890644 31 Q04721,P00533,P07858 3 +Defense response to symbiont 0.3465278436066431 0.6026153713978911 0.5467645921661368 1.0 0.8720648016890644 68 Q07021,P15260,O75844,Q96J02,O43657,Q13049,Q9HCL2 7 +Membrane repolarization 0.4692644604444093 0.5992722433566091 0.5489913542011204 1.0 0.8729157902386498 8 O75844 1 +Regulation of membrane potential 0.3525837992635603 0.5989111645303983 0.5492321259774562 1.0 0.8730520300587362 64 Q13614,P04062,P05067,Q8IWA4,P33176,Q14168,P0DP25,P29992,Q8N0X7,O00308,O75844,P46934,Q99808,Q14126,Q9UQB8,P31751,Q12959,Q06787,P78310,P05026 20 +Positive regulation of cysteine type endopeptidase activity 0.3712667207606537 0.5983543937515764 0.549603489587646 1.0 0.8730605800465522 33 Q99538,O95831,Q9Y6N7 3 +Regulation of smooth muscle contraction 0.5144810817561732 0.5978232456056156 0.5499578783461034 1.0 0.8731240478140405 5 P17301,Q14247 2 +Phosphatidylinositol biosynthetic process 0.3711030260301748 0.5970384167926843 0.55048173204938 1.0 0.8732138622946616 33 Q8TCG2,Q9NYA4,Q9BTU6,Q5H8A4,Q9NX62,O00459 6 +Axo dendritic protein transport 0.5516909016498297 0.5953612887139886 0.5516019959613416 1.0 0.8734432034006924 4 Q14168 1 +Protein localization to presynapse 0.5516909016498297 0.5953612887139886 0.5516019959613416 1.0 0.8734432034006924 4 Q14168 1 +Protein targeting 0.4049153396449213 0.5936732371155465 0.5527306865008021 1.0 0.8734432034006924 127 P33908,Q99523,Q9Y5Y5,P27105,Q99595,O95831,Q9NS69,P20645,Q8N4H5,P31751,P43307,P13473,Q92673,Q15629,O00560,Q13772,Q14108,P46934 18 +Regulation of dna damage response signal transduction by p53 class mediator 0.4446552025185 0.5932420020527761 0.5530192069602045 1.0 0.8734432034006924 11 O75844 1 +Calcium ion export across plasma membrane 0.6789967248120381 0.5928137276306592 0.5533058196471368 1.0 0.8734432034006924 3 P0DP25 1 +Positive regulation of epithelial cell proliferation 0.372807705246187 0.5911633570539384 0.5544109720108239 1.0 0.8734432034006924 32 Q04721,P17252,Q04656,P00533,P07942,O14786,Q9H2J4 7 +Regulation of glucocorticoid metabolic process 0.6881547139403839 0.5897270289030482 0.5553736712719122 1.0 0.8734432034006924 2 Q9UNE7 1 +Negative regulation of hormone metabolic process 0.6881547139403681 0.5897270289029944 0.5553736712719481 1.0 0.8734432034006924 2 O60678 1 +Cellular response to interferon gamma 0.3860471603690359 0.5834276744436383 0.5596054323184465 1.0 0.8755965860086616 23 Q08722,O60506,P23458,Q9UNK0,P08670 5 +Positive regulation of response to tumor cell 0.6760391091972748 0.583262556853473 0.5597165645505344 1.0 0.8755965860086616 3 Q92692 1 +Neural tube formation 0.3826865507029408 0.5824851230812271 0.5602399593919329 1.0 0.8755965860086616 26 O14641,P11233,O15031,P22694,Q13308,P17612,P98164 7 +Negative regulation of rna splicing 0.4003903813016381 0.5819552654089047 0.5605968134474157 1.0 0.8755965860086616 19 P38159,O75494,Q07021,P61978,P22626,Q16629,Q13242,P98175 8 +Bicarbonate transport 0.6755269613841708 0.5816141222186701 0.5608266283540166 1.0 0.8755965860086616 3 Q9Y6M7 1 +Cerebellar granular layer development 0.6857373086220989 0.5815529803065382 0.5608678221031311 1.0 0.8755965860086616 2 Q15058 1 +Cerebellar granular layer morphogenesis 0.6857373086220989 0.5815529803065382 0.5608678221031311 1.0 0.8755965860086616 2 Q15058 1 +Pyrimidine nucleotide metabolic process 0.3895682706584812 0.5796674484027597 0.56213889887971 1.0 0.8769680866601063 22 Q9H773 1 +Positive regulation of hydrolase activity 0.3804957793390979 0.578755999560163 0.5627538242933914 1.0 0.877055916179656 109 Q99538,P17301,P05556,Q9NR28,Q9NUM4,O95831,P29317,Q92542,P00533,P07602,O95819,P05067,Q9Y624,Q9Y6N7 14 +Regulation of sodium ion transport 0.399695991449716 0.5776024916294052 0.5635325243563281 1.0 0.8771958528302729 19 P05026,P46934,O43865,P27105 4 +Mitochondrial electron transport cytochrome c to oxygen 0.4725658956427925 0.5775118225676665 0.5635937544445173 1.0 0.8771958528302729 7 P20674,P00403,P10606,O14548,P13073,Q7KZN9 6 +Negative regulation of autophagy 0.3786350373067472 0.5746063541157683 0.5655575537343407 1.0 0.8780094336640146 28 O15118,Q07820,Q96KQ7,P10619 4 +Post golgi vesicle mediated transport 0.3627338279466471 0.5710472873775453 0.5679675889694611 1.0 0.8780555348346175 51 Q4J6C6,Q99523,O15127,P98194,Q92673,P11279,Q9UEU0 7 +Positive regulation of innate immune response 0.3702314911878926 0.5708131524398711 0.5681263064220508 1.0 0.8780555348346175 32 P11279,O43405,Q92692 3 +Multicellular organismal signaling 0.3763606508278028 0.5705058805656015 0.568334634772397 1.0 0.8780555348346175 29 P17301,Q14126,P17252,O75844,P04062,Q06787,P17612,P78310,P0DP25,P05026,P16615 11 +Stress fiber assembly 0.3722230478753595 0.5690046330906534 0.5693529957702312 1.0 0.8780555348346175 31 Q08722,Q9Y624,P05556,O14786 4 +Negative regulation of interleukin 1 production 0.6819769003491798 0.5689267484634715 0.5694058520359289 1.0 0.8780555348346175 2 P30740 1 +Negative regulation of interleukin 1 beta production 0.6819769003491798 0.5689267484634715 0.5694058520359289 1.0 0.8780555348346175 2 P30740 1 +Reproductive system development 0.3417183195421824 0.5682001427492454 0.5698990745507415 1.0 0.8780555348346175 81 Q04721,Q15392,P07858,O94813,P00533,P07602,Q13772,P98164 8 +Positive regulation of myeloid leukocyte differentiation 0.506569410509554 0.567634885805492 0.5702829138150012 1.0 0.8780555348346175 5 Q04721 1 +Kidney morphogenesis 0.4700803058937299 0.5669633263000561 0.5707390982198994 1.0 0.8780555348346175 7 Q12959,Q9Y5V3,P35222,O75844 4 +Neuron projection extension 0.3639724260912958 0.5664483892966489 0.5710890080331752 1.0 0.8780555348346175 40 O14965,Q9P265,O94813,Q13740,O14786,Q92581,P51805,P05556 8 +Post embryonic development 0.4006090504873625 0.5654536597684626 0.5717652352962228 1.0 0.8788923410447903 18 P11717 1 +Attachment of gpi anchor to protein 0.505913978494628 0.565151898463611 0.5719704509410644 1.0 0.8790061825744125 5 O43292,Q9H490,Q969N2,Q96S52 4 +Golgi localization 0.5425960763235748 0.5628598064247292 0.5735303516200478 1.0 0.8800136909317569 4 Q9Y678,P48444,P60953 3 +Positive regulation of neurotransmitter transport 0.5423586436253894 0.5620188266705433 0.5741031920642174 1.0 0.8804667261360148 4 P05556 1 +Regulation of receptor catabolic process 0.5049722644890309 0.5615893438029578 0.5743958424220366 1.0 0.8807140095887643 5 Q96J02 1 +Maintenance of protein location in cell 0.3791530978307841 0.5571121740228998 0.5774507903236015 1.0 0.8831755355428519 26 Q9H4A6,Q13438,P24390,Q12792,Q92673,Q99728 6 +Foam cell differentiation 0.6674643048251734 0.5558817598694511 0.5782916882395803 1.0 0.8839335946235716 3 P06756 1 +Ribonucleoside metabolic process 0.4442070951991481 0.5552921175078206 0.5786948695652971 1.0 0.8839335946235716 10 Q9Y6X5 1 +Purine ribonucleoside metabolic process 0.4442070951991481 0.5552921175078206 0.5786948695652971 1.0 0.8839335946235716 10 Q9Y6X5 1 +Positive regulation of receptor mediated endocytosis 0.4235077529549541 0.5545977974486163 0.5791697959037867 1.0 0.8839335946235716 13 P50897 1 +Mononuclear cell differentiation 0.3608932035694056 0.5539325046981433 0.5796250386914017 1.0 0.8839335946235716 51 Q9NQZ7,Q04721,P07711,P01889,Q04656,P04062,P24390,P05556 8 +Regulation of vascular endothelial growth factor receptor signaling pathway 0.5400550014696374 0.5538799336687418 0.5796610188556546 1.0 0.8839335946235716 4 P46934 1 +Negative regulation of vascular endothelial growth factor receptor signaling pathway 0.5400550014696374 0.5538799336687418 0.5796610188556546 1.0 0.8839335946235716 4 P46934 1 +Excretion 0.5025653374551164 0.5525107583372446 0.5805984655880909 1.0 0.8840515492499399 5 P04899 1 +Positive regulation of rna splicing 0.3804586957060661 0.5507974707545895 0.5817725181815665 1.0 0.8845736594944928 24 P98179,P62995,P38159,Q96QD8,Q96E39,Q14011 6 +Regulation of systemic arterial blood pressure by hormone 0.6646924528813871 0.5471327835623893 0.5842875108355747 1.0 0.8869524116919643 3 P42892 1 +Vasculature development 0.3903893211671077 0.5452304977332878 0.5855949986279263 1.0 0.8881325369550491 119 P42785,O14964,Q9Y6W5,P23458,Q14344,Q14118,Q13308,P35613,P06756,Q9NRA0,O95470,Q9H2J4,P98164,P01130,P29317,Q04656,Q13685,O14786,P05556,Q04721,Q08431,O94813,P43121,Q9H6E4,Q9BUP3,Q07954,Q9Y6N7 27 +Negative regulation of secretion 0.3879457453658297 0.5443120186892182 0.5862267777544792 1.0 0.8888232607498464 21 Q16850,P04899 2 +Regulation of transmembrane transport 0.3478162612909467 0.5428587380548394 0.5872270673572602 1.0 0.8898023525725429 87 Q16625,Q4KMQ2,P05067,P07947,O43865,Q9NRA0,Q06481,P17612,P0DP25,P22413,O00308,Q04656,O75844,P46934,P05556,P21796,P17252,P27105,P31751,Q06787,P05026 21 +Positive regulation of necrotic cell death 0.4854636643502615 0.5418181990516882 0.5879437529484486 1.0 0.8904856570080232 6 P30536,Q7Z3C6 2 +Positive regulation of actin filament bundle assembly 0.4004146934204688 0.5360402338347549 0.5919307442722759 1.0 0.8930159786754427 16 Q08722 1 +Cation transport 0.4583065399551193 0.5358744144070285 0.5920453482979153 1.0 0.8930159786754427 177 Q8TEL6,O15173,Q96QD8,Q4KMQ2,Q8N4V1,Q7KZN9,P55011,P05067,O43865,Q96NB2,P06756,Q9NRA0,P33176,Q8IUH4,P51790,Q9H7F0,Q9Y666,P04899,P51809,P17612,P0DP25,Q9NQ11,P98164,Q96RD7,P02792,Q9NWR8,O00429,O00308,Q04656,Q13423,P02786,O75844,O14936,P98194,Q6P4Q7,Q15043,P46934,P05556,P21796,Q99808,P17252,P08574,P27105,Q9UKS6,Q9H2J7,O00161,Q9BXP2,Q06787,Q9Y619,P08195,P30825,Q9HD20,Q92581,P05026,Q9Y6M7 55 +Embryonic organ morphogenesis 0.3732033982089616 0.5344453072980296 0.5930334796903791 1.0 0.8941530665657864 28 Q04721,O14641,Q96JA1,P54802,Q8N584,P29317,Q12959,Q13308,P35222 9 +Negative regulation of immune response 0.3827355072425927 0.5338735416356641 0.5934290287082447 1.0 0.8943961181098945 22 P04439 1 +Positive regulation of small molecule metabolic process 0.3978140238424816 0.5334407890048477 0.5937284884319487 1.0 0.8943961181098945 17 P05067 1 +Cation transmembrane transport 0.416449941006124 0.5317657837655804 0.5948882236589428 1.0 0.8955392800903491 141 Q8TEL6,Q4KMQ2,Q8N4V1,Q7KZN9,P55011,P05067,Q96NB2,P06756,Q9NRA0,Q8IUH4,P51790,Q9H7F0,Q9Y666,P17612,P0DP25,Q9NQ11,Q96RD7,Q9NWR8,O00308,Q04656,Q13423,P98194,Q6P4Q7,Q15043,P46934,P05556,P21796,P17252,P08574,P27105,Q9H2J7,Q9BXP2,Q06787,Q9Y619,P08195,P30825,Q9HD20,Q92581,P05026,Q9Y6M7 40 +Regulation of neuron projection arborization 0.5336110310683612 0.5313160263265067 0.595199801496745 1.0 0.8955435161944821 4 O14641 1 +Regulation of sodium ion transmembrane transport 0.399579849875786 0.5311687740981446 0.5953018294021655 1.0 0.8955435161944821 16 P46934,P27105 2 +Tube morphogenesis 0.4078683397189608 0.5310992792671537 0.5953499836495386 1.0 0.8955435161944821 134 P42785,O14964,Q9Y6W5,P22694,P23458,Q14344,Q14118,P00533,Q13308,P35613,P06756,P11233,O95470,O15031,P67870,Q9H2J4,P98164,P01130,O14641,P29317,Q13685,O14786,P05556,Q04721,Q08431,O94813,O00592,Q15375,P43121,Q9H6E4,Q9BUP3,Q07954,Q9Y6N7 33 +Embryonic morphogenesis 0.3589992846245387 0.5309902567914476 0.5954255309105658 1.0 0.8955435161944821 96 Q9NX62,P22694,Q14118,Q13308,P17301,P06756,Q96JA1,P11233,P54802,O15031,Q5SZK8,P10644,P17612,Q9Y2G5,P98164,O14641,P62993,P29317,P67809,P07942,P05556,P42892,Q04721,P17252 24 +Pigmentation 0.3821191783554986 0.5297542070904309 0.5962823588244082 1.0 0.896237158001533 22 O75787,Q86YV9,Q04656,Q8TAA9,O75882,P29992 6 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.4312971771497054 0.5277802004380681 0.597651900942352 1.0 0.8969317956897105 11 P14174,Q96K76,Q13049 3 +Inorganic ion transmembrane transport 0.4049118261366977 0.5257050150204448 0.599093178824019 1.0 0.8977616160455151 132 Q8TEL6,Q4KMQ2,Q8N4V1,Q7KZN9,P55011,Q8IWT6,P06756,Q9UHG3,Q9NRA0,Q8IUH4,P51790,Q9Y666,P17612,P0DP25,P51798,Q96RD7,Q9NWR8,O00308,Q04656,Q13423,P98194,Q6P4Q7,Q15043,P46934,P05556,P21796,P17252,P08574,P27105,Q9H2J7,Q9BXP2,Q06787,P08195,Q9HD20,Q92581,P05026,Q9Y6M7 37 +Positive regulation of protein export from nucleus 0.430319011160358 0.5230274404221308 0.6009551577195951 1.0 0.8988175556877317 11 P17612,Q14012,P50402 3 +Sulfate transport 0.6567138102691716 0.5222399570033601 0.6015032687913027 1.0 0.899137883415643 3 Q9H0H5 1 +Negative regulation of alpha beta t cell activation 0.530987913561025 0.5222194850311602 0.6015175208796617 1.0 0.899137883415643 4 Q96J02 1 +Positive regulation of dna binding transcription factor activity 0.3590928049761618 0.5220740198728887 0.6016187945669398 1.0 0.899137883415643 46 P02786,O75955,P41440,P05067,Q14254,Q13049 6 +Phosphatidylinositol metabolic process 0.357149872983623 0.5212916274257448 0.6021636326252395 1.0 0.8993761664302679 36 Q8TCG2,Q9NYA4,Q9BTU6,Q5H8A4,Q9NX62,O00459 6 +Schwann cell differentiation 0.421793088561418 0.5173991226791483 0.6048775719944968 1.0 0.9016658112782734 12 Q14118 1 +Positive regulation of neuron death 0.3900196291188113 0.5171972439910527 0.60501847572628 1.0 0.901675300048372 19 O95831,Q15375 2 +Bone development 0.363289872998969 0.5160867373807756 0.6057938305272204 1.0 0.9019084956123896 32 Q04721,Q92896,Q32P28,Q15904,Q9NX62,O75844 6 +Cellular response to alcohol 0.3799802522089182 0.5154744796471312 0.6062214985064625 1.0 0.9022643755252744 22 Q9NRA0,O95831,O43823,Q14118,O60266 5 +Regulation of platelet aggregation 0.6542794310283278 0.5147333008092493 0.6067393997448101 1.0 0.9024339673967416 3 Q9Y624 1 +Establishment of tissue polarity 0.4354134726965306 0.5140663368406013 0.607205612026898 1.0 0.9029270050597448 10 O14641,Q8TAA9 2 +Somatic diversification of immunoglobulins 0.3797308798963754 0.5138113212016622 0.607383911925794 1.0 0.9029917874282768 22 P02786,P13051 2 +Sterol biosynthetic process 0.3644974545448872 0.5091272817212684 0.6106630100538777 1.0 0.9060578909411308 31 Q15392,O75845,P56937,Q15800,Q9H2C2,Q16850 6 +Vascular associated smooth muscle cell proliferation 0.4341742329585658 0.5082960835013176 0.6112457162667151 1.0 0.9063205288538771 10 Q14344,Q9Y2S7,P04899,P08754 4 +Dna methylation or demethylation 0.372011917159975 0.5060017419270746 0.6128554268182786 1.0 0.907903861745381 26 Q9H9B1,Q8NB78,Q96KQ7 3 +Negative regulation of epithelial cell proliferation 0.3880829954418616 0.5051706489190889 0.6134389835286358 1.0 0.9083667847125316 19 Q9Y6N7,Q6YHK3 2 +Negative regulation of cellular amine metabolic process 0.6607574536663943 0.4998359049102696 0.617190626574424 1.0 0.9097238140407676 2 P23634 1 +Superoxide metabolic process 0.438738137823525 0.4996983597292367 0.617287487627199 1.0 0.9097238140407676 9 Q04656,P04899,P08754 3 +Positive regulation of intracellular protein transport 0.3386804013291074 0.4996214163063812 0.6173416750607896 1.0 0.9097238140407676 67 Q9Y282,P17252,P27105,P31751,Q9NR31,Q92673,Q9H270,O00459,Q14012,P50402,P17612,Q9NV96,Q92544,Q9Y3D6,Q92560,O94766 16 +Response to steroid hormone 0.3394994644081696 0.494735368982463 0.6207869316380745 1.0 0.9122596689419914 84 P16278,Q13185,Q969T9,O95831,Q9P1Z2,O15173,O94813,O15118,P04062,Q9H270,P46934,Q13772,P0DP25,P19021,Q05086 15 +Positive regulation of lamellipodium assembly 0.4054878459105061 0.4903012561231175 0.6239207382851988 1.0 0.9138567030253272 14 Q16625,Q04656 2 +Notch signaling pathway 0.3719203446988277 0.4866427169492498 0.6265115460796205 1.0 0.916356941857649 23 P05067,Q92542,Q9Y6N7 3 +Mitochondrial electron transport nadh to ubiquinone 0.3755076773242963 0.4857021087396986 0.627178388328266 1.0 0.9165738695041702 22 O43676,P51970,O96000,Q9Y6M9 4 +N terminal protein amino acid modification 0.4431166308155763 0.4853356361745178 0.6274382808110115 1.0 0.9166753741725526 8 Q86UY6 1 +Steroid biosynthetic process 0.3502854145898471 0.4848150358635014 0.62780755601927 1.0 0.9166753741725526 56 Q9BXW6,Q15392,O75845,P56937,Q13510,Q15800,Q9H2C2,Q16850 8 +Schwann cell development 0.4223140183610431 0.4843688634324896 0.6281241117960779 1.0 0.9167438582877424 11 Q14118 1 +Porphyrin containing compound metabolic process 0.3870438956707653 0.4829348710147132 0.6291419810463998 1.0 0.9178296815352572 18 P30519,P33527,P30536,P22830,Q7KZN9 5 +Peroxisomal transport 0.4420851177271461 0.4809346907479106 0.6305629162696711 1.0 0.9193022982030314 8 Q9Y5Y5 1 +Protein k48 linked ubiquitination 0.4141589193790602 0.4791099513918656 0.6318604106234766 1.0 0.9200276508766508 12 Q96J02,Q05086,Q13049 3 +Positive regulation of interferon beta production 0.4210666731053022 0.4783851042753698 0.6323761336193305 1.0 0.9203524891744056 11 O75955,P41440 2 +Protein polyufmylation 0.5173340499865609 0.4757497594356809 0.6342526663821058 1.0 0.9222741093714196 4 Q96HY6,Q9GZZ9,O94874 3 +Response to purine containing compound 0.380394091346029 0.4749987637658873 0.6347878544268788 1.0 0.9224784900239182 20 P05067,P35613 2 +Bergmann glial cell differentiation 0.4682504729056411 0.4749730999389266 0.6348061468203985 1.0 0.9224784900239182 6 Q7Z4L5 1 +Negative regulation of mapk cascade 0.352686227496706 0.47255889426344 0.6365279148191951 1.0 0.9232526108391476 39 P04062,Q14118,Q8NC42,Q92673 4 +Neurotransmitter reuptake 0.5154756717814902 0.4695446222641212 0.638680397292335 1.0 0.925499680573671 4 Q99808,P05556 2 +Monosaccharide metabolic process 0.330271329643216 0.4679918543298851 0.6397904148586684 1.0 0.9261003767365362 79 O00754,P16278,Q16706,P31751,Q9BRR6,Q92520,P10253,Q9BTY2,O75844,Q15043,Q8NBZ7,P11166,P04066 13 +Potassium ion transport 0.3621281328113588 0.4639329066855421 0.642695815743576 1.0 0.9287079252077288 29 P33176,O00308,Q4KMQ2,Q9BXP2,Q9Y666,P55011,P05026,Q92581,P46934,P05556 10 +T cell apoptotic process 0.4110303122352593 0.4635374622508399 0.6429791688271509 1.0 0.9287780445105432 12 Q9HCL2 1 +Regulation of myeloid leukocyte mediated immunity 0.4174665008566689 0.4611790585011013 0.6446701448619985 1.0 0.930265777092227 11 P51809,Q9NRA0 2 +Positive regulation of posttranscriptional gene silencing 0.3873832576606197 0.4605112125589911 0.6451493252093556 1.0 0.9306240578385412 16 Q9NRA8,P00533,Q06787,P51114 4 +Response to chemokine 0.477074599669222 0.4589801250625317 0.6462484385438878 1.0 0.9314316204561582 5 O94813 1 +Sarcomere organization 0.4233003890145082 0.4581285026795927 0.6468601225444264 1.0 0.9314365682508428 10 P10644,P05556 2 +Regulation of production of molecular mediator of immune response 0.3596574014320302 0.4577880798625035 0.6471047005183794 1.0 0.9314365682508428 30 P02786,P14174,P04439 3 +Detection of visible light 0.5113134421412631 0.4557562856163406 0.6485652421763874 1.0 0.9325613673463892 4 P29992 1 +Regulation of ion transport 0.3483178809709845 0.4555660747015891 0.6487020433555455 1.0 0.9325613673463892 93 P14174,Q4KMQ2,P55011,P05067,O43865,Q9NRA0,P33176,P04899,P51809,P17612,P0DP25,O00308,Q04656,O75844,O14936,P46934,Q7L0J3,P05556,P21796,P17252,P27105,Q9UKS6,Q06787,P05026 24 +Regulation of metal ion transport 0.3383865842944117 0.450533496763645 0.6523258068307671 1.0 0.9347632151763526 64 P21796,P17252,Q9NRA0,P27105,P33176,Q9UKS6,Q4KMQ2,Q04656,O00308,Q06787,O14936,P04899,P17612,P05026,P0DP25,P46934,O43865,P05556 18 +Positive regulation of b cell mediated immunity 0.4215500754267961 0.4501364418421483 0.6526120616705462 1.0 0.9348363273460758 10 P02786 1 +Peptidyl lysine hydroxylation 0.4418129334488515 0.449891823748542 0.6527884433849314 1.0 0.9348363273460758 7 Q92791,O00469,Q02809,Q96AY3 4 +Odontogenesis 0.3977819314672025 0.4491154264731298 0.6533483926686561 1.0 0.9348363273460758 14 Q6P4Q7,P35613,P19021 3 +Positive regulation of cellular protein catabolic process 0.3457247387230412 0.448453966490251 0.6538256015341055 1.0 0.9353125253962806 57 P01130,Q07954,P98164,P53634 4 +Regulation of leukocyte apoptotic process 0.4029361435147708 0.4477231087399 0.6543530418984833 1.0 0.9356676097298134 13 Q9HCL2 1 +Regulation of tube size 0.3971421351986419 0.4457163526807973 0.6558021507343379 1.0 0.9365845487590596 14 Q9HB40 1 +Cell migration involved in gastrulation 0.6308436324556622 0.4447391865129999 0.6565082469063921 1.0 0.9365845487590596 3 Q9HCM4,Q4VCS5 2 +Regulation of interleukin 1 mediated signaling pathway 0.6422240128928232 0.4427719863003026 0.6579306678754155 1.0 0.9377045661978316 2 Q86Y07 1 +Response to starvation 0.3489072653548694 0.4426537500241496 0.65801620036234 1.0 0.9377045661978316 51 Q96QD8,P04062,P13473,P11166,Q96KQ7 5 +Positive regulation of lipid localization 0.3905515702358192 0.4419869712247861 0.6584986339829833 1.0 0.9379931657712972 15 Q8WTV0,Q9NV96,P14174,Q07954 4 +Mrna 3 end processing 0.3493919461039012 0.4416573664321718 0.6587371650514391 1.0 0.9381335486984158 40 Q5KU26 1 +Negative regulation of ion transport 0.3720573342921118 0.4412366390501762 0.659041690905007 1.0 0.9383106849952756 21 Q9UKS6,P21796,P46934,Q04656 4 +Endothelial cell proliferation 0.3651817314322835 0.4408969905781159 0.6592875724395331 1.0 0.9383106849952756 23 Q8WTV0,P29317,O14786 3 +Cell surface receptor signaling pathway involved in cell cell signaling 0.3402056837454782 0.4401022728965779 0.6598630358211879 1.0 0.9387178994585088 88 Q9P1Z2,Q13614,P00533,Q13308,P50402,Q8TAA9,P16870,P05067,Q14168,P67870,O60716,Q13641,O14641,O75787,Q99808,Q7Z4L5,Q96C57,Q9UQB8,Q96K76,Q07954 20 +Cellular response to muramyl dipeptide 0.6276755708197507 0.4356120903211231 0.6631181972749798 1.0 0.9411112376753852 3 P08670 1 +Positive regulation of translation in response to stress 0.5040088745920626 0.4319360173318838 0.6657879164400609 1.0 0.9425666700425196 4 O00571,Q9P2X3 2 +Regulation of cardiac muscle cell action potential 0.4226718602553766 0.4289556125683026 0.6679555274933311 1.0 0.943326803001576 9 Q12959,P0DP25,Q14126,P78310 4 +Vesicle fusion with golgi apparatus 0.4560278262605808 0.4289104930923138 0.6679883636701303 1.0 0.943326803001576 6 Q9UEU0 1 +Hematopoietic stem cell homeostasis 0.5022843321687799 0.426384748897022 0.6698275126182012 1.0 0.9449874661778996 4 P55265,Q9NX40,Q14157 3 +Regulation of phosphoprotein phosphatase activity 0.3934737877291502 0.4262922904450057 0.6698948749345273 1.0 0.9449874661778996 14 O75663,Q8IV63,P42858,P42345,P67870,P04899,P0DP25 7 +Negative regulation of phosphoprotein phosphatase activity 0.4677345375996814 0.4260533077821156 0.6700690024759084 1.0 0.9450341865727144 5 P04899 1 +Negative regulation of protein polymerization 0.3584105877434499 0.4258340616788265 0.6702287651604597 1.0 0.9450606320440564 28 P45880 1 +Negative regulation of organic acid transport 0.623882965125431 0.4247967030096312 0.6709848813420787 1.0 0.945169632677688 3 P31751 1 +Negative regulation of ion transmembrane transport 0.3771609406406548 0.4235996337749202 0.671857822454625 1.0 0.9454707627420028 18 P21796,P46934,Q04656 3 +Developmental pigmentation 0.4156357111006772 0.423316830397082 0.6720641164030268 1.0 0.9454707627420028 10 P22413,P29992,O75787,Q86YV9 4 +Regulation of b cell mediated immunity 0.402542326205427 0.4216755696514265 0.6732618387744926 1.0 0.9461239577023371 12 P02786 1 +Interferon beta production 0.4025287967730555 0.4216093228000812 0.6733102003405165 1.0 0.9461239577023371 12 O75955,P41440 2 +Response to corticosterone 0.6225695909659272 0.4210799692010827 0.6736966878768793 1.0 0.9461239577023371 3 P0DP25 1 +Positive regulation of smooth muscle contraction 0.6219141539788157 0.4192307036197034 0.6750475349454681 1.0 0.9468749642537728 3 P17301 1 +Response to peptide 0.373612838263468 0.4161279594131168 0.6773163716883093 1.0 0.94827121851996 115 Q99523,Q14118,P63096,P05067,O43865,Q99538,P35613,P33527,Q92673,Q06481,P04899,P11166,P62993,O14654,P22413,Q8WWQ0,O00459,Q15043,Q9UQB8,P31751,Q07954,P08670 22 +Positive regulation of intracellular transport 0.3339895300227498 0.4156450011435758 0.6776697920265864 1.0 0.9483697945629948 85 Q13614,Q9H270,P50402,Q92560,Q9H4M9,Q92673,Q07666,Q14012,P17612,Q9P2W9,Q9NR31,O00459,Q9NV96,O94766,P46934,Q9Y282,P17252,P27105,P31751,Q9H3S7,Q92544,Q9Y3D6 22 +Regulation of potassium ion transport 0.375790332775197 0.4154333760743273 0.6778246778782684 1.0 0.9483885158956482 18 P33176,Q4KMQ2,O00308,P46934,P05026,P05556 6 +Apical junction assembly 0.3600570576274888 0.4148719197488198 0.6782356670077854 1.0 0.9487654853446414 25 P17252,P29317,Q16625,Q12959,P17612,Q9Y624 6 +Suppression of viral release by host 0.4519832231524714 0.4139539963896383 0.6789077981467639 1.0 0.9491114024154385 6 Q13049 1 +Cellular response to virus 0.3605445044978318 0.4133011528809215 0.6793859853040016 1.0 0.9492712217925022 24 Q9NUD5,Q07021,O43657,Q06787 4 +Regulation of biomineralization 0.4185232560723075 0.4110315901065947 0.6810493710193812 1.0 0.949530452376096 9 O75844,Q4KMQ2 2 +Regulation of neuron migration 0.4178425139831457 0.4081050996096352 0.6831965162461322 1.0 0.9517422296135823 9 O94898 1 +Defense response to other organism 0.4451077527556175 0.4080513262786013 0.6832359934098853 1.0 0.9517422296135823 176 Q92485,P14174,P01889,P15260,O43823,O00584,Q5KU26,P23458,Q9Y3E7,O43405,Q07021,Q96J02,Q06481,P51809,P04439,Q9BY67,P29317,Q08722,O60506,O75844,O43657,Q13137,P11279,Q04721,P10321,Q9UNK0,Q13049,Q9HCL2,Q92692 29 +Protein transport along microtubule 0.4624849979617199 0.4079017491475321 0.6833458085497699 1.0 0.9517422296135823 5 Q14168 1 +Negative regulation of mrna processing 0.3593705657733324 0.405285074490211 0.6852679763367138 1.0 0.9530329897092044 24 P38159,O75494,Q07021,P61978,P22626,Q16629,Q13242,Q99728 8 +Lipopolysaccharide mediated signaling pathway 0.405382707163578 0.4041921025451099 0.6860714607313625 1.0 0.953589480827991 11 Q8WTV0,P14174,Q9UBC1 3 +Glyoxylate metabolic process 0.6160485225979708 0.402848445773708 0.6870597193157546 1.0 0.9540161526564408 3 P48735 1 +Spindle midzone assembly 0.4487919802095115 0.4022598070467267 0.6874928313142643 1.0 0.9540161526564408 6 Q9H0H5,Q02241 2 +Cell cell signaling by wnt 0.3259615152804803 0.4020914248780557 0.6876167433894209 1.0 0.9540161526564408 80 Q07954,O14641,Q7Z4L5,Q96C57,Q9P1Z2,O75787,Q96K76,P00533,Q13308,Q9H3S7,P50402,Q13641,O60716,P05067,O00571,P67870,Q8TAA9,P16870 18 +Positive regulation of vasculature development 0.3592801066794024 0.4011211974733192 0.688330895001585 1.0 0.9545196892821484 23 P23458,Q9H2J4,O14786 3 +Export from cell 0.4321773343834458 0.4004146280565838 0.6888511518462317 1.0 0.9545217278928454 165 P14174,P51149,Q4KMQ2,Q9H270,Q9Y3E7,P55011,P16870,P19021,Q9UEU0,P16615,Q8IWT6,P50897,P11233,Q32P28,Q9NRA0,P33527,Q86YV9,Q8WU76,Q16850,P04899,P51809,O95721,P0DP25,P54920,Q9NQ11,P56545,Q4J6C6,O00429,O14936,Q5SQN1,P11279,Q7L0J3,Q96PC5,P20645,P51151,Q96KC8,O00161,Q12959,Q06787,O00213,Q92783,O00560,Q9H3S7,Q15833,Q9NZ43,O43760,P05026,O14964 48 +Exocrine system development 0.422746449069089 0.4000252081005183 0.6891379500915307 1.0 0.9545217278928454 8 Q14118,O14786 2 +Cartilage development involved in endochondral bone morphogenesis 0.45973317942928 0.3984935826689092 0.6902663877555899 1.0 0.9545414806860588 5 Q15643,O75844,P16435 3 +Negative regulation of protein dephosphorylation 0.422293275529613 0.398168689376626 0.6905058442128975 1.0 0.9545414806860588 8 P04899 1 +Histone h2a acetylation 0.4035249954951649 0.3955446691496161 0.6924409623419479 1.0 0.955868039055764 11 Q86UY6,Q9NRA0 2 +Response to light stimulus 0.3257984201577477 0.3938469895854324 0.6936940097408382 1.0 0.9574005875788916 69 P31751,Q96K76,P22830,Q06787,P00533,Q13049,Q14011,P05067,Q6AZY7,P46934,P05556 11 +Sodium ion homeostasis 0.4265946360452718 0.3895047170443576 0.6969028219271654 1.0 0.9603925189411312 7 P05026,P04899 2 +Regulation of morphogenesis of a branching structure 0.4904164361781715 0.3889701634532385 0.6972982179034097 1.0 0.9603971755833646 4 Q9Y5V3,P35222 2 +Negative regulation of cellular catabolic process 0.3556505294454488 0.388640433677558 0.6975421518116782 1.0 0.9605357512722144 103 Q96HR8,Q9UL15,Q13614,Q9Y2S7,Q14011,P46379,Q14103,Q07820,Q92530,Q92673,P60520,O94898,P10619,Q99729,Q96KQ7,Q9NQ11,Q9H2J4,Q9NNW5,Q9GZT3,Q08J23,O60506,P67809,Q93009,P35637,Q9NRA8,Q13151,Q92804,Q06787,O00560,O15118 30 +Establishment or maintenance of monopolar cell polarity 0.4077513657817118 0.3880418680287653 0.6979850502202907 1.0 0.960750833143641 10 Q14517 1 +Epidermal cell differentiation 0.3421273844734101 0.3871239977078111 0.6986644124568491 1.0 0.9610937792048037 38 P29317,Q16739,Q13510,Q6YHK3 4 +Regulation of immune system process 0.4832961774134807 0.3849572193638146 0.7002691115136579 1.0 0.9617645641290442 215 Q92485,P14174,Q9HAT2,P01889,Q4KMQ2,Q5KU26,O75955,O00115,O15400,P05067,P07947,Q99538,P17301,Q9NQZ7,O43405,Q9NRA0,P53634,Q07021,P10644,Q96J02,Q07666,Q06481,P51809,Q7KYR7,Q6AZY7,Q5ZPR3,Q9UBC1,Q96QR8,P01130,Q9NPF0,P04439,Q9BY67,Q6PIJ6,Q08722,P02786,O43657,P11279,Q14254,Q04721,Q00013,O94813,Q9NPR9,P30825,P41440,Q9HCL2,Q92692 46 +Negative regulation of phosphorus metabolic process 0.3486672245387845 0.3840297510904505 0.7009563968783614 1.0 0.9617645641290442 98 Q86XL3,Q16625,O94813,Q9BRG1,P04062,Q92673,P10644,P04899,Q9H3E2,Q6YHK3,Q07954 11 +Protein maturation by protein folding 0.4553763440860172 0.3837533916009548 0.7011612359781219 1.0 0.9617645641290442 5 O00170,P27797,O76024,Q96HE7 4 +Positive regulation of mrna splicing via spliceosome 0.3721660483992063 0.3828654467871903 0.7018195322941763 1.0 0.9617645641290442 17 P98179,P62995,P38159,Q96E39,Q14011 5 +Trna transcription 0.4551039003590846 0.382838098322994 0.7018398112011608 1.0 0.9617645641290442 5 Q12789 1 +Negative regulation of calcium ion transmembrane transport 0.4115708299328291 0.3813464785713181 0.7029461696229258 1.0 0.962243715035304 9 Q06787,P21796 2 +Mitotic spindle midzone assembly 0.4541396663383077 0.379604871216502 0.7042387443267066 1.0 0.9630295989548232 5 Q9H0H5,Q02241 2 +Epithelial cell development 0.3430498977318104 0.3791954439386085 0.7045427345989066 1.0 0.9632487570954452 45 O00592,Q14517,P29317,Q9Y624 4 +Heart development 0.3637602079797272 0.3778338734200751 0.7055540084089631 1.0 0.9636959403548692 110 P42892,Q04721,P05556,Q14126,Q8NDZ4,O94813,Q5SZK8,P10253,O75844,P10644,P00533,P78310,O14786,P16870,Q9Y6N7,P19021,P98164 17 +Regulation of vesicle fusion 0.4530743587839723 0.3760440041342447 0.7068841822530927 1.0 0.9646788412665908 5 P31751 1 +Tetrahydrobiopterin metabolic process 0.6060098292469355 0.3755286602048431 0.707267335662592 1.0 0.9648088100164242 3 P00374 1 +Lymphocyte apoptotic process 0.3703691128723738 0.3725265930661529 0.7095008160691505 1.0 0.9664785506698064 17 P24390,Q9HCL2 2 +Indole containing compound metabolic process 0.6047367927077112 0.3721306924534168 0.7097955454359042 1.0 0.9666596765266368 3 Q04656 1 +Cell junction maintenance 0.3981359362362058 0.3706460463297629 0.7109011810113435 1.0 0.9668979606953187 11 Q96J84,Q15334,Q6IQ23,Q12959,P56545 5 +Protein localization to extracellular region 0.3220702562711157 0.3705632354063059 0.7109628693384857 1.0 0.9668979606953187 70 Q8IWT6,Q9H4A6,Q96PC5,Q32P28,O00255,P20645,Q86YV9,Q15334,P20337,O00429,Q96KC8,O00213,Q16850,Q9H3S7,P55011,Q9NQ11,P19021 17 +Regulation of epithelial to mesenchymal transition 0.403178982234413 0.3678553241507908 0.7129811141340845 1.0 0.9682673610793586 10 O00560 1 +Protein targeting to membrane 0.3404545228287415 0.3627584322238468 0.7167853459376285 1.0 0.971072445618352 41 Q9Y5Y5,P27105,P31751,P43307,Q15629,O00560 6 +Positive regulation of lamellipodium organization 0.3684792824387765 0.3616890098589593 0.7175844406918093 1.0 0.9711023077423624 17 Q16625,Q04656 2 +Regulation of proton transport 0.4058616353311117 0.3573226324243195 0.7208502886512171 1.0 0.9727526316970984 9 Q9NRA0 1 +Positive regulation of binding 0.3328103801031488 0.3572182458766111 0.7209284275797505 1.0 0.9727526316970984 61 P17301,Q07954,O75955,O14786,P05067,P41440,O75503,P56545 8 +Regulation of mitochondrial fission 0.3948171485223723 0.355457360366554 0.7222469833614207 1.0 0.9733605717263925 11 O14965,P11233,O00429,Q9GZY8,Q9Y3D6 5 +Regulation of skeletal muscle cell differentiation 0.5967221923696862 0.351092525040395 0.7255189356033473 1.0 0.9759991783246956 3 P17844,Q9BYT8 2 +Postsynaptic signal transduction 0.4344183244591902 0.3508323883722515 0.7257140973064271 1.0 0.9760657997486804 6 P04899 1 +Calcium ion transport 0.3299175560222817 0.3498701473076018 0.7264361518017282 1.0 0.9768409087831424 63 Q96RD7,Q8TEL6,P06756,P21796,Q9NRA0,Q9NWR8,Q9UKS6,O00429,Q4KMQ2,P98194,O75844,Q06787,O14936,P04899,P08195,P17612,P0DP25,P05026 18 +Germ cell development 0.3396216917349397 0.3488570784310172 0.7271966096147167 1.0 0.9771335640347396 46 O14965,Q96RD7,Q9GZT3,Q92879,Q8N2A8,Q08J23,Q8IXJ6,P17252,Q01085,A0AVF1,P42345,Q12768,P07686,P17612,P35222,Q96KQ7,Q92692 17 +Response to insulin 0.3201152739598015 0.3488283769029622 0.7272181582693951 1.0 0.9771335640347396 70 Q99523,P62993,O14654,Q9UQB8,Q8WWQ0,P31751,Q92673,O00459,P04899,Q06481,P11166,Q15043 12 +Neural tube development 0.3356668027480234 0.348803312193319 0.7272369766346285 1.0 0.9771335640347396 35 O14641,P11233,O15031,P29317,O75787,P22694,Q13308,P17612,P98164 9 +Regulation of wnt signaling pathway 0.3361545071983747 0.3483368767407533 0.7275872023085665 1.0 0.9774081839791569 56 Q07954,Q7Z4L5,Q96C57,O75787,Q96K76,P00533,Q13308,P50402,O60716,P05067,O00571,Q13641 12 +Response to arsenic containing substance 0.3782964475786901 0.3472402800012272 0.7284108121673174 1.0 0.9781224730806172 14 Q96QD8,Q9BWF3 2 +5s class rrna transcription by rna polymerase iii 0.4758898120218958 0.3451644256568303 0.7299707613662711 1.0 0.9792054017467856 4 Q12789 1 +Regulation of rna splicing 0.3385310688993858 0.3444176322515201 0.7305322304885 1.0 0.9792054017467856 93 P52597,P62995,Q9BWF3,Q92879,Q13595,Q9UHX1,Q96QD8,Q9UKA9,P22626,P52756,Q14011,P31943,Q12849,Q5BKZ1,O75494,Q07021,Q96E39,Q07666,P55795,P98179,P31483,P38159,P31942,P51116,Q13242,P35637,P61978,P51114,Q16629,Q06787,Q07955,Q8IXT5,P98175 33 +Regulation of extent of cell growth 0.3497564829519388 0.3438539956754246 0.7309560906451629 1.0 0.9795776283751012 25 Q15375,P51805,O14786 3 +Regulation of glucan biosynthetic process 0.4752265759637747 0.3432196596875797 0.7314332156971035 1.0 0.9796293788173436 4 P31751 1 +Regulation of glycogen metabolic process 0.4752265759637747 0.3432196596875797 0.7314332156971035 1.0 0.9796293788173436 4 P31751 1 +Post translational protein modification 0.3817109680137182 0.3410395340651178 0.7330738199848241 1.0 0.9798765699417876 13 O75718,Q32P28 2 +Regulation of mitotic centrosome separation 0.5926921010209489 0.3407491607396547 0.7332924261089295 1.0 0.9798765699417876 3 P43487,O14757 2 +Peroxisome organization 0.3769449282642175 0.3403149760728395 0.7336193402395037 1.0 0.9798765699417876 14 Q9Y5Y5,Q9GZY8,O00429,O14678,Q9Y3D6,O14734,P56589 7 +Negative regulation of hormone secretion 0.4136632598171151 0.3399649127116933 0.7338829514214609 1.0 0.9798765699417876 7 P40939,Q6WKZ4,Q06124,Q8N183,Q16836,Q8N5M9 6 +Peptide antigen assembly with mhc protein complex 0.6048885307547747 0.3384883019633357 0.7349952410821514 1.0 0.979916780537156 2 P27797 1 +Embryonic brain development 0.4307924675991584 0.3382011384682533 0.7352116179816734 1.0 0.979916780537156 6 P62995,Q9BVA1 2 +Regulation of blood circulation 0.3385734652833297 0.3378908089167621 0.7354454740669065 1.0 0.979916780537156 33 P42892,Q14126,P17252,P10253,O75844,Q12959,P17612,P78310,P0DP25,P05026 10 +Positive regulation of vesicle fusion 0.47339870113332 0.3378856930291318 0.735449329469098 1.0 0.979916780537156 4 P31751 1 +Negative regulation of cell matrix adhesion 0.3960317978709871 0.336732368079878 0.7363186607010264 1.0 0.9800239867125936 10 O14936 1 +Regulation of osteoclast differentiation 0.440480789306565 0.3348789759491216 0.7377163821020734 1.0 0.9800239867125936 5 Q04721,P42345 2 +Cellular anion homeostasis 0.5896031898446759 0.3329303485588877 0.7391868601745921 1.0 0.9800239867125936 3 P55011 1 +Chaperone mediated protein complex assembly 0.3840781242098978 0.3328873753241461 0.7392192995172633 1.0 0.9800239867125936 12 O95456 1 +Dephosphorylation 0.3348341336332724 0.3327384360985928 0.7393317333361495 1.0 0.9800239867125936 91 O75663,Q86XL3,Q3ZCQ8,Q13614,Q9NX62,Q9UNW1,P04062,Q96PE3,P11117,P17301,Q9NYA4,P04899,P67870,P0DP25,Q16537,P78318,P42345,Q9ULE6,Q9P0J1,P10586,Q12959,Q9H3S7,P34913 23 +Establishment of planar polarity of embryonic epithelium 0.4712974216535326 0.3318010694852286 0.7400394766586504 1.0 0.980768157517555 4 O14641 1 +Positive regulation of nad p h oxidase activity 0.5877598555916539 0.328310006536229 0.7426772790039784 1.0 0.9811596932554038 3 P04899 1 +Regulation of nad p h oxidase activity 0.5877598555916539 0.328310006536229 0.7426772790039784 1.0 0.9811596932554038 3 P04899 1 +Positive regulation of i kappab kinase nf kappab signaling 0.33699809374787 0.3261176158576527 0.7443353694589252 1.0 0.9821885501306786 45 Q8TB61,Q8WVQ1,Q8IUH4,P02786,O43657,Q13049 6 +Cell morphogenesis 0.4745791325319441 0.3251089202308524 0.745098638001735 1.0 0.9822287710243172 212 O14965,Q9P265,Q9Y6W5,P19022,Q13740,Q14344,Q14118,O75955,P00533,P46108,P05067,P51805,Q9Y624,Q9ULH0,P98155,Q14517,P35613,P06756,O43405,O15031,P33176,Q07021,P07686,Q06481,P38571,Q9P2X3,Q13641,P98164,Q8N0X7,P13591,Q9BVA1,O14641,Q9NUM4,P29317,Q8WWQ0,Q04656,O75844,Q9Y4F1,O95819,P07942,O14786,P46934,P05556,P42892,Q04721,Q92581,Q92859,Q14185,Q15058,Q9UQB8,O94813,Q12959,Q15375,O00213,P41440,O75882,Q8NEN9,Q05086,Q9Y6N7 59 +Transmembrane transport 0.5092853044595775 0.318801297255383 0.7498771945018001 1.0 0.9825538787290464 250 Q3ZCQ8,Q9C0H2,P55011,P05067,O43865,Q8IWT6,P33527,P51790,Q9Y666,Q06481,P17612,P0DP25,P98164,Q9NWR8,Q03519,P22413,O14925,Q13423,Q7L0J3,P21796,P27105,Q99595,P45880,Q9H2J7,P30825,Q92581,Q8NHS3,Q99523,Q9NS69,Q16625,Q96QD8,P23786,P04062,Q15629,Q8WTV0,Q9UHG3,Q8IUH4,Q9H7F0,P51798,Q9H2D1,Q8NE01,O75844,Q9NV96,Q15043,O95831,Q9BXP2,Q9Y619,P08195,P41440,Q9HD20,Q8IXU6,Q9Y6M7,Q8TB61,P06756,Q9NRA0,P11166,Q9NQ11,Q96RD7,Q9Y5Y5,Q04656,Q6P4Q7,P46934,P05556,P31751,O14678,Q06787,P05026,Q8TEL6,Q4KMQ2,Q8N4V1,Q7KZN9,P07947,Q07820,Q96NB2,P98194,Q99808,Q9Y277 77 +Mrna modification 0.3809492729754169 0.318197427559106 0.7503351839531196 1.0 0.9825538787290464 12 Q08J23 1 +Process utilizing autophagic mechanism 0.4545827367193342 0.3171912138373263 0.7510985163216293 1.0 0.9825538787290464 193 Q9BXS4,Q93050,Q7Z3C6,Q13501,P27544,P51149,P13473,P04062,Q9H270,P07602,Q8WUH2,Q9Y2S7,Q9Y487,Q9Y3E7,Q07820,Q9UEU0,P16615,Q9NYA4,P53365,Q9Y6I9,O15269,P60520,Q14145,P51809,P17612,O95721,P10619,Q9NNW5,Q96KQ7,Q9NQ11,Q96CP6,Q9UK41,Q9H9H4,P08754,Q86Y82,Q5MNZ6,O00429,P42345,O75844,O00459,Q13137,P46934,O15027,Q9H0U4,P21796,P17252,Q9UNE7,Q9BRG1,P30536,Q92783,Q8TDY2,Q13049,Q6PHR2,Q9Y3D6,O15118,Q8NHS3,O14964 57 +Regulation of cell substrate adhesion 0.3354671222455833 0.3161137640619273 0.751916159813987 1.0 0.9825538787290464 50 Q07021,P14543,Q14118,O14936,O14786 5 +Fat cell differentiation 0.333805844280913 0.3160968752332692 0.751928978445993 1.0 0.9825538787290464 34 Q8N4Q0,Q99523,P31751,P56545 4 +Peptidyl proline modification 0.3315873338015816 0.3155678846088459 0.7523305172993666 1.0 0.9825538787290464 35 O75718,Q32P28,Q9BV86,O15460,Q9NWM8 5 +Aging 0.3184587290415473 0.3154192631791698 0.7524433428562256 1.0 0.9825538787290464 80 P53634,O75844,P02786,Q14118,P04062,P67809,P05067 7 +Mitochondrial electron transport ubiquinol to cytochrome c 0.5823580496575844 0.3149692298721056 0.7527850166727017 1.0 0.9825538787290464 3 P08574 1 +Cellular response to ketone 0.3454955396450207 0.3147972177582648 0.7529156243274864 1.0 0.9825538787290464 25 Q9NRA0,O95831,O43823,O60266,Q13772 5 +Cardiac muscle cell cardiac muscle cell adhesion 0.4327408620570727 0.3104737907574326 0.7562006873621399 1.0 0.984229181354887 5 P78310 1 +Dna ligation 0.3943473742887189 0.3099318983213571 0.7566127450086337 1.0 0.984229181354887 9 P18887,Q96JA1 2 +Regulation of hormone biosynthetic process 0.5797958087049893 0.3087462773699786 0.7575145381718378 1.0 0.984229181354887 3 P05023,P16435 2 +Regulation of steroid hormone biosynthetic process 0.5797958087049893 0.3087462773699786 0.7575145381718378 1.0 0.984229181354887 3 P05023,P16435 2 +Positive regulation of protein autophosphorylation 0.404833436402858 0.3071919505013558 0.7586972720902572 1.0 0.985042448188474 7 P0DP25,P61225 2 +Nucleoside phosphate catabolic process 0.3440072338520175 0.3046980736866552 0.7605961168700666 1.0 0.9856122089652706 25 Q9H773,P13051 2 +Negative regulation of apoptotic signaling pathway 0.3190825311258187 0.3038671780463975 0.7612290842363088 1.0 0.9860373642349712 68 O95881,P06756,P14174,P08754,Q9UL15,P45880,Q8WWQ0,Q96K76,P04899,Q7LG56,O14786,Q07820,Q8TDY2,Q13049 14 +Keratinization 0.5895782970722445 0.300297779923223 0.7639500265019643 1.0 0.9876529856512664 2 Q9Y3B8 1 +Mitochondrial fragmentation involved in apoptotic process 0.4193544054823538 0.2993311629276411 0.7646873793906817 1.0 0.987924970342725 6 Q9Y3D6,O00429 2 +Somatic diversification of immune receptors 0.3383211511923294 0.2981272528644293 0.7656060420187258 1.0 0.9886496519478808 30 P02786,P13051 2 +Homeostasis of number of cells 0.3211535600873134 0.2967033730132918 0.7666929816519612 1.0 0.9892961437906682 66 Q92542,P04062,O00115,P38571,Q9HCL2 5 +Regulation of substrate adhesion dependent cell spreading 0.3536477107169213 0.2964486654394479 0.7668874649124784 1.0 0.9892961437906682 19 Q13418,Q14185,Q07021,P50570,P46108,O14786 6 +Lipid import into cell 0.4015043757824861 0.2950750873334044 0.7679365202946475 1.0 0.9895617302470155 7 P11166 1 +Response to virus 0.3314751946727411 0.2945909057496901 0.7683064101968828 1.0 0.9896470788709352 91 P61916,P15260,Q07021,O75844,Q96J02,Q06787,O43657,Q13049,Q9HCL2 9 +Regulation of dna primase activity 0.5736163353035939 0.2940206852234479 0.7687420970935679 1.0 0.9896483931465794 3 P49643,Q9BRT9 2 +Myoblast differentiation 0.3858913477789011 0.293557593136733 0.7690959844059113 1.0 0.9897237495177452 10 Q14254,P05556 2 +Protein insertion into er membrane 0.3672916102144846 0.2914694786532572 0.7706922835173524 1.0 0.990979097328997 14 P46379,Q8N4V1,Q15629 3 +Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 0.4568664337543687 0.2914215155093646 0.7707289613034656 1.0 0.990979097328997 4 Q9UII2,P30419,O75146 3 +Protein dephosphorylation 0.3217989899063229 0.2902121660636388 0.7716539293752933 1.0 0.990979097328997 65 O75663,Q86XL3,Q3ZCQ8,Q9NYA4,Q9ULE6,P42345,Q9UNW1,Q13614,P04062,Q9P0J1,P10586,P67870,P04899,Q12959,Q9H3S7,P0DP25,Q16537 17 +Negative regulation of actin filament bundle assembly 0.3800181323740073 0.2892133182495154 0.772418140660017 1.0 0.9913340441791332 11 Q9Y624 1 +Nephron development 0.347865933570331 0.2884237882027307 0.7730223606999811 1.0 0.9914541725251282 21 O00592,P14543 2 +Regulation of muscle organ development 0.3888561854393059 0.287872374565882 0.7734444340891662 1.0 0.9914541725251282 9 P41440 1 +Response to sodium arsenite 0.570392262224602 0.2864984900542625 0.7744963497875799 1.0 0.9915566686845526 3 P09651,Q9UER7 2 +Cellular response to reactive nitrogen species 0.393600587830518 0.285012240779615 0.7756347639170178 1.0 0.9917016309371268 8 O95831,Q14103 2 +Ribonucleoprotein complex localization 0.3933767884140993 0.2841670749143614 0.7762823462117843 1.0 0.9923029342573676 8 Q96ST2,Q08J23 2 +Positive regulation of platelet derived growth factor receptor signaling pathway 0.5815202793446103 0.2813425260466373 0.7784476958885285 1.0 0.9932256769228424 2 O75146 1 +Response to platelet derived growth factor 0.3870499529369559 0.2806976846917294 0.7789422847362446 1.0 0.9932824617927968 9 Q04656 1 +Regulation of golgi organization 0.38276997812684 0.2805180650886506 0.7790800676771465 1.0 0.9932824617927968 10 Q9P2W9 1 +Ion transmembrane transport 0.4415976809671849 0.280461406967895 0.7791235305348749 1.0 0.9932824617927968 184 Q8TEL6,Q8TB61,Q4KMQ2,Q8N4V1,Q9C0H2,Q7KZN9,P55011,P05067,O43865,Q96NB2,Q8IWT6,P06756,Q9UHG3,Q9NRA0,Q8IUH4,P33527,P51790,Q9H7F0,Q9Y666,P17612,P0DP25,P51798,Q9NQ11,P98164,Q96RD7,Q9H2D1,Q9NWR8,O00308,Q04656,Q13423,O75844,P98194,Q6P4Q7,Q15043,P46934,P05556,P21796,P17252,P08574,P27105,P45880,Q9H2J7,Q9Y277,Q12959,Q9BXP2,Q9Y619,Q06787,P08195,P30825,P41440,Q9HD20,Q92581,P05026,Q9Y6M7 54 +Negative regulation of peptide secretion 0.4135520301156142 0.2802104397875645 0.7793160575928764 1.0 0.9933389535921372 6 P40939,Q06124,Q8N183,Q16836,Q8N5M9 5 +Exploration behavior 0.451040905278436 0.2758434673514839 0.7826682962661777 1.0 0.9949626179013512 4 Q05086 1 +Positive regulation of organic acid transport 0.3954161806481464 0.2732728241401735 0.7846435037529709 1.0 0.9959622655591688 7 P14174,P05556 2 +Phosphatidylinositol acyl chain remodeling 0.5644814615797873 0.2729986421391051 0.7848542593603804 1.0 0.9960298056205767 3 Q96N66,Q6UWP7 2 +Embryo implantation 0.3760916770711556 0.2720822918366062 0.7855587451637436 1.0 0.9961455037771172 11 P35613,Q07021,P47914 3 +Homotypic cell cell adhesion 0.3451449903979924 0.2716590280207462 0.7858842077378627 1.0 0.9961455037771172 21 Q14126,P23458,P78310,P61225,Q9Y624 5 +Positive regulation of phosphorus metabolic process 0.4200121038842528 0.2715142769836314 0.7859955205397298 1.0 0.9961455037771172 165 Q86XL3,P14174,Q8NDZ4,Q13501,P04062,Q14118,O75955,P00533,P05067,Q9H223,P07947,P98155,P17301,P67870,Q14012,P0DP25,O14641,P29317,P02786,P14635,Q6PJG6,P51116,O14786,P61225,P12956,O00571,Q15058,P31751,P51114,Q12959,Q15375,Q06787,O00560,P41440,Q8TDY2,Q9Y6N7 36 +Negative regulation of catabolic process 0.3617676388490612 0.271345168151946 0.7861255699011 1.0 0.9961455037771172 116 Q9UL15,P00533,Q14011,Q14103,Q07820,Q92673,O94898,Q16850,Q8N9N5,Q99729,P10619,Q96KQ7,Q9NQ11,Q9H2J4,Q08J23,O60506,P67809,P35637,Q92804,Q06787,O00560,O15118 22 +Myelin assembly 0.4100136123252671 0.2687576436358296 0.7881161898875442 1.0 0.9979132258882148 6 Q13614 1 +Myeloid leukocyte mediated immunity 0.3488616134290413 0.2684563309326441 0.7883480843566271 1.0 0.998018296440898 19 P51809,Q9NRA0,O00161 3 +Muscle tissue development 0.321887542960688 0.2674060571696374 0.7891565362516166 1.0 0.9980990952931372 63 Q04721,P05556,Q8NDZ4,O75844,O75955,P10644,P50402,P78310,P41440,P98164 10 +Superoxide anion generation 0.4092943697879405 0.2664493380385935 0.7898931718077471 1.0 0.9984654917871596 6 P04899 1 +Negative regulation of fibroblast proliferation 0.3933065176150626 0.265829136497124 0.7903708026214302 1.0 0.9988808446480908 7 P50402 1 +Regulation of arp2 3 complex mediated actin nucleation 0.3829706594897198 0.2646478733329686 0.79128073699874 1.0 0.9991416954400734 9 P53365 1 +Lymphocyte homeostasis 0.3789166757724057 0.2645935258136453 0.7913226080865279 1.0 0.9991416954400734 10 Q9HCL2 1 +Establishment of protein localization to membrane 0.3352489027832343 0.262492165282684 0.7929420248587302 1.0 1.0 96 Q4J6C6,Q9Y5Y5,P27105,Q9NS69,Q15904,P31751,P43307,P00533,Q15629,Q8N4V1,O00560,P05026,Q9HD20,O60725,O15118 15 +Respiratory electron transport chain 0.3296043067466195 0.2615140684303763 0.7936961018624404 1.0 1.0 49 P43304,O43676,P51970,P04062,P14635,Q7KZN9,O96000,Q9Y6M9 8 +Primary mirna processing 0.4163847218440254 0.2613255847801286 0.793841438072743 1.0 1.0 5 P22626 1 +Intracellular distribution of mitochondria 0.558814744180993 0.2604147095948121 0.7945438976636618 1.0 1.0 3 O00429 1 +Inner ear morphogenesis 0.3733172553125898 0.2600995541987111 0.794786981792901 1.0 1.0 11 Q8N584,O14641,Q96JA1,Q13308 4 +Maintenance of animal organ identity 0.5718506580714504 0.2596684515207523 0.7951195300841261 1.0 1.0 2 Q99959 1 +Er overload response 0.444504165546896 0.2588786063792441 0.7957289052686376 1.0 1.0 4 Q9UM00,O76024,Q96A33 3 +Neurofilament cytoskeleton organization 0.5702390545259111 0.2561713754681841 0.797818510388395 1.0 1.0 2 Q16352 1 +Positive regulation by symbiont of entry into host 0.5699704539349958 0.2555917539552592 0.7982660863515156 1.0 1.0 2 P19474 1 +Response to mineralocorticoid 0.3848514032087291 0.2524552531138492 0.8006891969608745 1.0 1.0 8 O95831 1 +Immunoglobulin production 0.3345492624500742 0.2487679913993033 0.8035402520247572 1.0 1.0 27 P02786,P13051 2 +Protein insertion into membrane 0.3313155512049759 0.2467661233232424 0.8050892294939176 1.0 1.0 30 Q9NS69,P00533,Q8N4V1,Q15629,P46379 5 +Negative regulation of insulin secretion involved in cellular response to glucose stimulus 0.5656728444802487 0.2464435180332173 0.8053389222629241 1.0 1.0 2 Q8N5M9 1 +Protein targeting to mitochondrion 0.3278961400716497 0.2462308372322516 0.8055035456064212 1.0 1.0 49 Q15388,Q3ZCQ8,Q96EP0,Q9NS69,Q99595,O95831,Q8N4H5,Q9GZY8,O14925,P30536,Q9H270,P55786,Q9Y3D6,Q92560 14 +Regulation of striated muscle cell differentiation 0.3695406734141622 0.2439571653705144 0.8072639947910858 1.0 1.0 11 P67809 1 +Positive regulation of fatty acid biosynthetic process 0.5643298415256435 0.2436333640963447 0.8075147859493432 1.0 1.0 2 P04083 1 +Striated muscle cell development 0.3575065578888778 0.2431807993381334 0.8078653403841543 1.0 1.0 14 Q16527,P28289,Q9NYL9,P10644,P05556 5 +Escrt complex disassembly 0.4009142242538275 0.2400579704919657 0.8102853162653141 1.0 1.0 6 Q8WUX9,Q9UN37,Q9UQN3,Q9NZZ3,O75351 5 +Positive regulation of anion transport 0.3813326064459819 0.2396511692930199 0.8106006930749339 1.0 1.0 8 P05556,P14174,P55011 3 +Convergent extension 0.5488820575388035 0.239219778845449 0.8109351665428466 1.0 1.0 3 O14641 1 +Midbody abscission 0.3762109795478977 0.2385410167750758 0.8114615065268469 1.0 1.0 9 Q8WUM4,Q8WUX9,O95235,Q9UN37,Q9UQN3,Q9NZZ3,Q9Y3E7,O75351 8 +Wnt protein secretion 0.5483610961848381 0.2381388071927572 0.8117734365837204 1.0 1.0 3 Q9H3S7,Q96QK1 2 +Phenol containing compound biosynthetic process 0.4080688535951141 0.2376818000013258 0.8121279006973177 1.0 1.0 5 Q04656 1 +Alternative mrna splicing via spliceosome 0.3260773551631151 0.2329600456604242 0.8157924311642106 1.0 1.0 44 P62995,P31483,P38159,Q9BWF3,P51114,Q06787,Q07666,Q07955,P51116,Q13242 10 +Regulation of heart rate by chemical signal 0.5589578297072185 0.2326256389827198 0.8160521163930985 1.0 1.0 2 P62258 1 +Chemical homeostasis 0.4665928125070442 0.2324387218118566 0.8161972766889845 1.0 1.0 213 Q93050,P62995,P42785,P30519,Q15904,P22694,Q9NWW5,Q14344,P04062,Q9Y487,P55011,P05067,Q8WTV0,O15254,O75503,P35610,Q8IWT6,P06756,Q9H4M9,P50897,P61916,P51790,Q9H7F0,Q86YV9,P07686,Q9Y666,Q06481,P04899,P17612,Q13772,P0DP25,O15260,Q9NQ11,P01130,P02792,Q9NUM4,Q9NWR8,Q8NE01,O75787,Q04656,P98194,P02786,O00459,Q16739,Q6P4Q7,Q96CP7,Q15043,Q7L0J3,Q99808,Q92859,Q8N511,Q9BXP2,P34913,Q92544,P05026,Q9HD20,Q92581,Q9HCL2,O15118,Q05086,Q9Y6M7 61 +Regulation of anoikis 0.4061573577641221 0.2323812177724061 0.8162419357243582 1.0 1.0 5 P05556 1 +Positive regulation of cell substrate junction organization 0.3665874276234303 0.2314741648860833 0.8169464539105968 1.0 1.0 11 O14786 1 +Positive regulation of canonical wnt signaling pathway 0.3361179682028409 0.2312427990950245 0.8171261820263269 1.0 1.0 22 Q7Z4L5,O75787,Q96K76,P00533,Q13308 5 +Cell communication involved in cardiac conduction 0.3586238228018382 0.2307353463687796 0.8175204119168629 1.0 1.0 13 Q14126,P17612,P78310,P0DP25,P05026 5 +Peripheral nervous system development 0.3506715335778939 0.230589129331049 0.8176340135849673 1.0 1.0 15 Q14118 1 +Positive regulation of early endosome to late endosome transport 0.3828744186844773 0.2299038422642872 0.8181664906001913 1.0 1.0 7 Q9H270,Q13614 2 +Gene silencing by rna 0.3259623497062221 0.2289725550809405 0.818890247358637 1.0 1.0 49 Q9NRA8,Q9BWF3,Q9UKZ1,Q01085,P51114,Q5KU26,P22626,P00533,O75844,Q06787 10 +Histone h3 k14 acetylation 0.3779720205514795 0.2275848727422914 0.8199689811726749 1.0 1.0 8 Q96ES7 1 +Monoubiquitinated protein deubiquitination 0.3731003373577718 0.2267410173405081 0.8206251304188183 1.0 1.0 9 Q96ES7,Q96K76,Q93009 3 +Negative regulation of dendrite morphogenesis 0.5560032232070844 0.2267307943403825 0.8206330801980439 1.0 1.0 2 Q9Y4G8 1 +Membrane depolarization during action potential 0.556003223207084 0.2267307943403817 0.8206330801980446 1.0 1.0 2 Q12955 1 +Establishment of golgi localization 0.5424502955400243 0.2260907321064424 0.82113085268865 1.0 1.0 3 Q9Y678,P60953 2 +Adherens junction maintenance 0.430688079826229 0.2248764053160298 0.8220754250424509 1.0 1.0 4 Q6IQ23 1 +Vesicle tethering 0.3951313188103758 0.2224039761808131 0.8239994167858247 1.0 1.0 6 O95772 1 +Hypotonic response 0.539890204752165 0.220996658379362 0.8250950348846793 1.0 1.0 3 P17301 1 +Phospholipid biosynthetic process 0.3036702515551798 0.2194658805556644 0.8262871553632385 1.0 1.0 73 Q8TCG2,Q9NRA0,Q9NYA4,O75874,Q9BTU6,Q5H8A4,Q86YN1,Q9HCL2,Q13614,Q9NX62,P07686,O15269,Q9UG56,O00459,O15228,Q96PE3,P35790 17 +C4 dicarboxylate transport 0.3711206864503636 0.2193039958748917 0.8264132494067247 1.0 1.0 9 Q8IWT6,P55011,Q9UBX3 3 +Positive regulation of cilium assembly 0.3999999999999931 0.2156569183061231 0.8292551851665109 1.0 1.0 5 P27695,Q9UHD8,P42858,Q15555 4 +Regulation of histone deacetylation 0.351761219327958 0.215469900354736 0.829400976949985 1.0 1.0 14 O43823,Q9NRA0 2 +Cell cell junction assembly 0.3198717112259671 0.2147995805869016 0.8299235799090012 1.0 1.0 36 P17252,P19022,Q16625,P29317,O00192,Q12959,O15228,P17612,O60716,Q9Y624 10 +Intraciliary transport 0.3782670136526265 0.2145252523046409 0.8301374768184735 1.0 1.0 7 Q7Z4L5 1 +Negative regulation by host of viral genome replication 0.549556809024968 0.2142636726830198 0.8303414451755429 1.0 1.0 2 O75909 1 +Regulation of hydrolase activity 0.445541298936808 0.2123998730768667 0.8317950847888609 1.0 1.0 194 Q99523,P07858,P00533,P07602,P05067,P51805,Q9Y624,Q99538,P17301,P50897,Q9NRA0,Q92673,Q06481,P04899,Q14108,Q9NQ11,Q9NUM4,Q15392,P29317,O95819,Q15043,P05556,O43847,Q9NR28,O95831,Q92542,P31751,Q15375,Q6YHK3,Q07954,Q9Y6N7 31 +Ether metabolic process 0.369230712457921 0.2122576523282636 0.8319060312011926 1.0 1.0 9 O15228,O00116,P07099,P34913 4 +Response to progesterone 0.3774960838657981 0.2119823589384711 0.8321207971010156 1.0 1.0 7 Q969T9,Q05086 2 +Voluntary musculoskeletal movement 0.4248425027485462 0.2112712806815624 0.832675591815506 1.0 1.0 4 P18887 1 +Lamellipodium morphogenesis 0.3770844540075324 0.2106282138904286 0.8331773946718091 1.0 1.0 7 Q9Y6W5,Q92766,Q9BR76,Q13596,Q8IZP0,O60749 6 +Calcium mediated signaling using intracellular calcium source 0.4241136478682462 0.2096081670290319 0.833973504878361 1.0 1.0 4 P17252,P17612 2 +Negative regulation of leukocyte cell cell adhesion 0.3566644983593474 0.2084493034548078 0.8348781630977855 1.0 1.0 12 P10644 1 +Regulation of lipid kinase activity 0.3902917398994192 0.2079933956174775 0.83523412412539 1.0 1.0 6 O00459 1 +Positive regulation of dopamine receptor signaling pathway 0.5457964007520791 0.2072415883621783 0.8358211894475409 1.0 1.0 2 Q96QK1 1 +Regulation of dopamine receptor signaling pathway 0.5457964007520791 0.2072415883621783 0.8358211894475409 1.0 1.0 2 Q96QK1 1 +Regulation of ossification 0.3558556826967739 0.2049394048593004 0.8376194679345699 1.0 1.0 12 O75844,Q4KMQ2 2 +Regulation of cation transmembrane transport 0.3191962389347449 0.2045433330012138 0.8379289328669568 1.0 1.0 59 P21796,P17252,Q9NRA0,P27105,Q4KMQ2,P0DP25,Q04656,O00308,Q06787,P17612,P05026,P05067,P46934,P05556 14 +Imp salvage 0.5300913487372318 0.2021988747220909 0.8397612528038387 1.0 1.0 3 P07741,Q01433 2 +Regulation of cell matrix adhesion 0.325128958793442 0.2019922878508649 0.8399227533204523 1.0 1.0 30 Q14118,O14936,O14786 3 +Regulation of fatty acid metabolic process 0.3370671708445375 0.2009023691364456 0.8407749151804453 1.0 1.0 19 Q2T9J0,Q06481 2 +Response to lithium ion 0.5417673918882583 0.1999229811687309 0.8415408168881946 1.0 1.0 2 P27797 1 +Regulation of actin filament bundle assembly 0.3255964500655841 0.1980175021098079 0.8430313701608965 1.0 1.0 29 Q08722,Q9Y624,O14786 3 +Ion transport 0.4877017299054109 0.1979009817168013 0.8431225360697745 1.0 1.0 239 Q8TEL6,P14174,Q8TB61,O15173,Q96QD8,Q4KMQ2,Q8N4V1,Q9C0H2,P07602,Q7KZN9,P55011,P05067,O43865,Q96NB2,Q8IWT6,P06756,Q9UHG3,Q9NRA0,P33176,Q8IUH4,P33527,P51790,Q9H7F0,Q9Y666,P04899,P51809,P17612,P11166,P0DP25,P51798,Q9NQ11,Q86WC4,P98164,Q9H813,Q96RD7,P02792,Q9H2D1,Q9NWR8,Q8NE01,P22413,O00429,O00308,Q08722,Q13423,P02786,O75844,Q04656,O14936,P98194,Q6P4Q7,Q9H0H5,Q15043,P46934,Q7L0J3,P05556,P21796,Q99808,P17252,P08574,O43681,P27105,P45880,Q9UKS6,Q9H2J7,Q9Y277,O00161,Q9BXP2,Q06787,Q9Y619,P08195,P30825,P41440,Q9HD20,Q92581,P05026,Q9Y6M7 76 +Positive regulation of mammary gland epithelial cell proliferation 0.4188812455372107 0.197887361831939 0.8431331924462475 1.0 1.0 4 Q86VI3 1 +Positive regulation of release of cytochrome c from mitochondria 0.3866630814735043 0.1974116912407626 0.8435053813569886 1.0 1.0 6 Q96A26,O00429,Q9GZY8,P04637,O14737 5 +Presynaptic modulation of chemical synaptic transmission 0.5274046211714041 0.197239846333883 0.843639850167831 1.0 1.0 3 Q9Y2X7,P35268 2 +Regulation of presynaptic cytosolic calcium ion concentration 0.5274046211714041 0.197239846333883 0.843639850167831 1.0 1.0 3 P20020,P23634 2 +Cardiocyte differentiation 0.3276921189620808 0.1959930139440291 0.8446156340217399 1.0 1.0 25 O75844,P00533,P78310 3 +Regulation of protein acetylation 0.3266794670379997 0.1949302148114966 0.8454475798915808 1.0 1.0 27 Q9P265,Q9NRA0,Q969T9,Q01105,O75844,Q14012,O00571 7 +Cellular response to gonadotropin stimulus 0.5260612573884915 0.194791963944612 0.8455558136302344 1.0 1.0 3 P48506,P16435 2 +Cellular response to follicle stimulating hormone stimulus 0.5260612573884915 0.194791963944612 0.8455558136302344 1.0 1.0 3 P48506,P16435 2 +Response to gonadotropin 0.5260612573884915 0.194791963944612 0.8455558136302344 1.0 1.0 3 P48506,P16435 2 +Response to follicle stimulating hormone 0.5260612573884915 0.194791963944612 0.8455558136302344 1.0 1.0 3 P48506,P16435 2 +Positive regulation of protein acetylation 0.3433961979763777 0.194296314753895 0.8459438710532499 1.0 1.0 15 Q969T9,Q9P265,Q14012,Q9NRA0 4 +Regulation of adenylate cyclase activity 0.3851017429711857 0.1929185007124516 0.8470227957266938 1.0 1.0 6 P04899 1 +Oxidative demethylation 0.5369325812516659 0.1914206709142572 0.8481960264457289 1.0 1.0 2 Q6P6C2 1 +Oxidative rna demethylation 0.5369325812516659 0.1914206709142572 0.8481960264457289 1.0 1.0 2 Q6P6C2 1 +Macromolecule deacylation 0.3208116786642359 0.1906919137463832 0.8487669743366042 1.0 1.0 43 Q9UMR5,P50897,Q9NRA0,O43823,Q9UBU8 5 +Granulocyte activation 0.3633444503339951 0.1906579598335394 0.8487935776103681 1.0 1.0 9 Q15833,P12429,P04083,P51809 4 +Skeletal muscle cell differentiation 0.3669588435316528 0.1892049879390173 0.8499321584638049 1.0 1.0 8 P50402 1 +Regulation of p38mapk cascade 0.3896449456642969 0.1887683464492907 0.8502743816543892 1.0 1.0 5 O43164 1 +Negative regulation of nf kappab transcription factor activity 0.3348930699801909 0.1886952348778735 0.850331686515295 1.0 1.0 19 Q96J02,Q86VP1 2 +Histone h3 k9 acetylation 0.3831894511825834 0.1874650425893199 0.8512960297516428 1.0 1.0 6 Q9NRA0 1 +Response to oxidative stress 0.3550181251324389 0.1836533792974059 0.8542853846345024 1.0 1.0 117 P30519,Q9UL15,O75306,P04062,P00533,P18887,P05067,Q07820,Q9NWX6,O43169,P33527,Q14145,Q9P2X3,Q6AZY7,Q9NQ11,Q15392,O75874,Q04656,P00374,Q9NR28,Q8N0U8,Q9UJ14,O95831,O75882,Q05086 25 +Cellular process involved in reproduction in multicellular organism 0.3169625146698641 0.1827968588176581 0.8549574133857063 1.0 1.0 59 Q96RD7,Q8NB78,Q08J23,O94813,P07686,P78310,Q96KQ7,Q92692 8 +Cellular response to ph 0.5192207219407292 0.1826550411004666 0.8550686941940207 1.0 1.0 3 Q9P2X3 1 +Positive regulation of megakaryocyte differentiation 0.5188070929607651 0.1819387570979009 0.8556307883015082 1.0 1.0 3 P26583,Q9GZP4 2 +Negative regulation of ire1 mediated unfolded protein response 0.530754767660488 0.1810004881450695 0.8563671928587782 1.0 1.0 2 Q96HY6 1 +Positive regulation of glial cell proliferation 0.5307547676604747 0.1810004881450477 0.8563671928587953 1.0 1.0 2 P30536 1 +Epithelial cell differentiation 0.3609633851083938 0.1808840345424409 0.8564586007241193 1.0 1.0 122 Q04721,O14773,P21796,Q14517,P17301,P07858,P31942,P29317,Q13510,O00592,P07602,Q16739,Q6YHK3,O14786,Q9Y624,Q9Y6M7 16 +Regulation of rig i signaling pathway 0.3642934356576329 0.1801957966099367 0.8569988582404497 1.0 1.0 8 Q07021 1 +Cellular response to nitrogen compound 0.4034771576214867 0.1801788363870374 0.8570121726341848 1.0 1.0 158 Q9NUD5,Q5KU26,O75955,P00533,Q14103,P05067,O43865,Q99538,Q9Y2Q5,P33527,Q92673,Q06481,P04899,P17612,Q9P2X3,P29992,Q99729,Q96KQ7,P62993,O14654,P08754,P09471,Q8WWQ0,Q04656,O00459,Q15043,O95831,Q9UQB8,Q92542,P31751,O94813,Q06787,P41440,Q07954,P08670 35 +Subpallium development 0.5299489658877115 0.1796779683820114 0.8574053906185126 1.0 1.0 2 Q02218 1 +Striatum development 0.5299489658877115 0.1796779683820114 0.8574053906185126 1.0 1.0 2 Q02218 1 +Modulation by host of symbiont process 0.3252045950949683 0.178958896816522 0.8579699761920789 1.0 1.0 24 P11717 1 +Regulation of hematopoietic stem cell proliferation 0.5288745635240264 0.1779277321061483 0.8587797312670482 1.0 1.0 2 O95251 1 +Icosanoid biosynthetic process 0.3495392457947771 0.1778896786679512 0.8588096167945678 1.0 1.0 12 P14174,Q9UJ14 2 +Viral protein processing 0.3595102511842001 0.1768789420771683 0.8596034795952272 1.0 1.0 9 Q10472,Q16706 2 +Skeletal system morphogenesis 0.324827511389334 0.1765576613229464 0.8598558528922295 1.0 1.0 24 O75844,Q92896,Q9NX62 3 +Meiotic spindle assembly 0.4080217021814216 0.1748013462187263 0.861235730495846 1.0 1.0 4 O14965,Q12768 2 +Response to nitric oxide 0.3589155908929085 0.1747629970676953 0.8612658648734675 1.0 1.0 9 O95831,Q14103 2 +Negative regulation of phosphatase activity 0.3653962105664137 0.1732548157508764 0.8624511383201605 1.0 1.0 7 P04899 1 +Response to human chorionic gonadotropin 0.5259199570239071 0.1731917965028789 0.862500671646073 1.0 1.0 2 P48506 1 +Negative regulation of protein autophosphorylation 0.5119637954122589 0.1703799556348879 0.8647113347466835 1.0 1.0 3 Q9P2X3 1 +Negative regulation of wnt signaling pathway 0.3236376755197658 0.1696403006669155 0.8652930265275729 1.0 1.0 25 Q07954,Q13641,P50402 3 +Regulation of growth 0.3780400024172505 0.1690695613073351 0.8657419267899202 1.0 1.0 137 O75629,P00533,P05067,P51805,Q99538,P50897,Q9NRA0,Q96J02,Q9BQT9,O75844,P02786,O14786,O94813,Q96K76,Q15375,O00560,Q13049,O75882,Q9HCL2 19 +2 oxoglutarate metabolic process 0.3543729343405153 0.1681360800863497 0.8664762255695495 1.0 1.0 10 P48735,Q9H9P8 2 +Regulation of sulfur metabolic process 0.509940891993544 0.1670685346563535 0.8673161237208684 1.0 1.0 3 Q15120,O75027 2 +T cell differentiation in thymus 0.3539040234164571 0.166384687909123 0.8678542232738278 1.0 1.0 10 P04062,P35222,O96005 3 +Cardiac epithelial to mesenchymal transition 0.5088662009672122 0.1653288616825014 0.8686851430571625 1.0 1.0 3 Q53EL6,Q9NQC3 2 +Endocardium development 0.5088662009672122 0.1653288616825014 0.8686851430571625 1.0 1.0 3 Q13043,Q13188 2 +Cardiac muscle cell action potential 0.3331978882016285 0.1649569100191299 0.868977898169077 1.0 1.0 16 Q14126,Q12959,P78310,P0DP25,P05026 5 +Transcription initiation from rna polymerase iii promoter 0.5080089267808253 0.1639508629538504 0.8697698259485092 1.0 1.0 3 Q12789 1 +Gmp salvage 0.402579951625915 0.1638704622982157 0.8698331203970953 1.0 1.0 4 P07741,P55263,P00492 3 +Negative regulation by host of viral transcription 0.4023112066648701 0.163341749441662 0.8702493639852407 1.0 1.0 4 Q13547,Q9H1E3,Q13148 3 +Tongue development 0.5075228371842999 0.1631733475338116 0.8703819505251551 1.0 1.0 3 Q13547,P35222 2 +Hair follicle placode formation 0.5075228371842999 0.1631733475338116 0.8703819505251551 1.0 1.0 3 Q13547,P35222 2 +Fungiform papilla morphogenesis 0.5075228371842999 0.1631733475338116 0.8703819505251551 1.0 1.0 3 Q13547,P35222 2 +Tongue morphogenesis 0.5075228371842999 0.1631733475338116 0.8703819505251551 1.0 1.0 3 Q13547,P35222 2 +Fungiform papilla development 0.5075228371842999 0.1631733475338116 0.8703819505251551 1.0 1.0 3 Q13547,P35222 2 +Response to amphetamine 0.5075228371842998 0.1631733475338113 0.8703819505251553 1.0 1.0 3 P0DP25,P00492 2 +Regulation of receptor clustering 0.5058354987059842 0.1604959221818284 0.8724904336170944 1.0 1.0 3 Q15334 1 +Cellular response to interleukin 1 0.3429750803238426 0.160370020628132 0.8725896040147718 1.0 1.0 13 Q08722 1 +Positive regulation of non motile cilium assembly 0.3998925020155808 0.1586305572099233 0.8739599524485597 1.0 1.0 4 P27695,Q9UHD8,Q15555 3 +C terminal protein lipidation 0.5162503357507298 0.1584797834259627 0.8740787498305373 1.0 1.0 2 O95352 1 +Cellular response to zinc ion 0.5040885016564547 0.1577590263895776 0.8746466864642912 1.0 1.0 3 Q9NQ11 1 +Protein quality control for misfolded or incompletely synthesized proteins 0.3446324204149606 0.1573364096634337 0.8749797268236486 1.0 1.0 12 P46379,Q16740 2 +Ubiquinone metabolic process 0.3598708983324358 0.1563390191110738 0.8757658016551715 1.0 1.0 7 Q9Y5Z9,P22570,Q5T2R2,Q16795,Q86YH6,Q8NI60 6 +Female meiosis i 0.5029309095098456 0.1559652162831745 0.8760604390293145 1.0 1.0 3 O14965 1 +Mitochondrion localization 0.3273402969073438 0.1546997186929715 0.8770580517746349 1.0 1.0 20 Q9BUK6,O00429,Q92692,Q6PJG6 4 +Regulation of actomyosin structure organization 0.3193359003421092 0.1542662215116234 0.8773998297870487 1.0 1.0 29 Q08722,Q9Y624,O14786 3 +Cellular response to ether 0.4999999999999902 0.1514936101164538 0.8795863510538591 1.0 1.0 3 Q9H4A6,P11802 2 +Protein refolding 0.3465326079308144 0.1502686508034552 0.8805526651542459 1.0 1.0 11 P48723 1 +Regulation of phosphatase activity 0.3290220912952741 0.1502038678144815 0.8806037744418109 1.0 1.0 18 O75663,P17301,P42345,P67870,P04899,P0DP25 6 +Hypoxia inducible factor 1alpha signaling pathway 0.5098039215686181 0.149335253924173 0.8812890985435013 1.0 1.0 2 Q15120 1 +Regulation of acyl coa biosynthetic process 0.5098039215686181 0.149335253924173 0.8812890985435013 1.0 1.0 2 Q15120 1 +Atrioventricular canal development 0.5087295192049338 0.1478622003922634 0.8824515199478147 1.0 1.0 2 Q06124 1 +Ventricular trabecula myocardium morphogenesis 0.5087295192049338 0.1478622003922634 0.8824515199478147 1.0 1.0 2 Q15648 1 +Trabecula morphogenesis 0.5087295192049338 0.1478622003922634 0.8824515199478147 1.0 1.0 2 Q15648 1 +Heart trabecula morphogenesis 0.5087295192049338 0.1478622003922634 0.8824515199478147 1.0 1.0 2 Q15648 1 +Regulation of behavior 0.3570306740877407 0.1478387368540428 0.882470037636454 1.0 1.0 7 P42345,Q7Z4L5 2 +Anoikis 0.3568699139356069 0.147361632655881 0.882846587561926 1.0 1.0 7 Q07820,P42345,P05556 3 +Tetrapyrrole biosynthetic process 0.3367745492672799 0.1457235047540313 0.8841396653284836 1.0 1.0 14 P22830 1 +Regulation of neuron differentiation 0.3195176097286019 0.143030581355045 0.88626602906553 1.0 1.0 24 P05067,Q8WUJ1,Q9NRA8,Q13049 4 +Hormone mediated signaling pathway 0.3157914663537654 0.1418812324833654 0.8871738186469207 1.0 1.0 52 P42785,Q9P1Z2,O15173,Q9H270,P67870,Q06481,Q13772,P46934,Q05086 9 +Cellular response to insulin stimulus 0.3133474333814378 0.1416316170765788 0.8873709918534334 1.0 1.0 58 O14654,P62993,Q9UQB8,Q8WWQ0,P31751,Q92673,O00459,P04899,Q06481,Q15043 10 +Localization within membrane 0.4547706753034084 0.1412989671019343 0.8876337655620707 1.0 1.0 210 Q9BXS4,Q13501,Q9NS69,Q15904,O75955,Q14118,Q15629,P07602,P00533,O15400,Q8N4V1,P16870,Q9H223,O60725,Q9UEU0,Q9Y624,P35613,Q9H4M9,Q9HD45,P11233,Q99805,Q86YV9,P43307,Q14168,Q92673,Q13641,Q4J6C6,Q9Y5Y5,P29317,Q14254,P05556,O43752,Q9HD20,P27105,P31751,Q9UNK0,Q9BTX1,O00560,Q92544,P41440,P05026,Q07954,O15118 43 +Negative regulation of lymphocyte activation 0.3322300382037489 0.1403590066049398 0.8883763451539706 1.0 1.0 15 P10644 1 +Cell cell junction organization 0.3156770913989004 0.1393277445275914 0.8891911667331427 1.0 1.0 51 Q14126,P17252,Q96J84,P19022,Q16625,P29317,O00192,Q6IQ23,Q12959,O15228,Q9H3S7,P17612,P78310,O60716,Q9Y624 15 +Regulation of actin nucleation 0.3463626172020834 0.1387330147098235 0.8896611283966189 1.0 1.0 10 P53365 1 +Entrainment of circadian clock 0.368403946252801 0.1386964934477128 0.8896899891417078 1.0 1.0 5 Q9BWF3 1 +Peroxisome proliferator activated receptor signaling pathway 0.3682795698924834 0.1384240583248764 0.8899052842478541 1.0 1.0 5 Q15120,Q96EK7,Q15648,O43707 4 +Positive regulation of leukocyte apoptotic process 0.3682795698924656 0.1384240583248374 0.889905284247885 1.0 1.0 5 P42771,P04083,Q9Y4G8,P04637 4 +Plus end directed organelle transport along microtubule 0.4893208674411017 0.1360477158224364 0.8917835598332635 1.0 1.0 3 P33176 1 +Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway 0.4892530897366917 0.1359539069354437 0.8918577194781101 1.0 1.0 3 O75351,Q8WUM4 2 +Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.3525422863531288 0.1346820723703434 0.8928632482050267 1.0 1.0 7 P14174 1 +Positive regulation of viral life cycle 0.3500186576844242 0.1339225862025512 0.8934637899616595 1.0 1.0 8 Q06787 1 +Regulation of protein kinase activity 0.354161685544047 0.1339047654412554 0.89347788194888 1.0 1.0 120 P14174,Q8NDZ4,O14964,P04062,Q14118,P00533,P05067,P98155,P10644,Q92673,Q14012,P0DP25,O14641,Q99640,P14635,P61225,P12956,O00571,Q15058,Q9BRG1,Q9Y6N7 21 +Oocyte maturation 0.3629400240690003 0.13320025147263 0.8940350119732656 1.0 1.0 6 O14965,Q12768 2 +Positive regulation of protein tyrosine kinase activity 0.3627448857319618 0.1327092414446606 0.8944233339010288 1.0 1.0 6 O14641,Q15334 2 +Regulation of perk mediated unfolded protein response 0.4961052914316274 0.1316280347505596 0.8952785099310356 1.0 1.0 2 P57088 1 +Negative regulation of establishment of protein localization to mitochondrion 0.4958366908407184 0.1313038530858166 0.8955349438609268 1.0 1.0 2 O95429 1 +Negative regulation of jun kinase activity 0.4958366908407179 0.1313038530858161 0.8955349438609272 1.0 1.0 2 Q53EL6 1 +Leukocyte homeostasis 0.3358743488063753 0.1298328953519358 0.8966986364513503 1.0 1.0 13 Q9HCL2 1 +Protein localization to axon 0.4846856528747896 0.1297540760709575 0.896760997641056 1.0 1.0 3 Q12955,Q9Y2J2 2 +Regulation of response to interferon gamma 0.4841483073616233 0.1290404194265363 0.8973256660991822 1.0 1.0 3 Q16543,Q15648 2 +Regulation of myoblast differentiation 0.3617266903173009 0.1244194075622208 0.9009832077286052 1.0 1.0 5 Q14254 1 +Phospholipid metabolic process 0.326581753554085 0.1221162702111784 0.9028069365511642 1.0 1.0 99 Q92485,P01130,Q8WTV0,Q8TCG2,Q9NRA0,Q9NYA4,Q92484,Q9BTU6,Q8NHP8,P35790,Q9NX62,P07686,Q8NCC3,Q9HCL2 14 +Neuroblast division 0.4785061794733924 0.1217456653017239 0.9031004465253668 1.0 1.0 3 Q96N67,P61026 2 +Asymmetric neuroblast division 0.4785061794733924 0.1217456653017239 0.9031004465253668 1.0 1.0 3 Q96N67,P61026 2 +Protein localization to cell cell junction 0.3427098961239264 0.1193928284340181 0.904964142736746 1.0 1.0 9 Q9Y624 1 +Base excision repair 0.3156262588829105 0.1188187082519421 0.9054189866410528 1.0 1.0 24 P18887,Q96K76,P13051 3 +Negative regulation of transforming growth factor beta production 0.4840182648401716 0.1178915321530589 0.9061536028210682 1.0 1.0 2 Q9Y5K6 1 +Regulation of mrna splicing via spliceosome 0.3040252625742637 0.1168271619018359 0.9069970190492233 1.0 1.0 66 P62995,Q9BWF3,Q92879,Q9UHX1,P98175,P22626,P52756,Q14011,O75494,Q07021,Q96E39,Q07666,P98179,P31483,P38159,P51116,Q13242,P61978,P51114,Q16629,Q06787,Q13595 22 +Positive regulation of low density lipoprotein receptor activity 0.4745261304337688 0.1168164268766745 0.9070055261121984 1.0 1.0 3 P61978 1 +Vesicle mediated transport to the plasma membrane 0.3107355088206351 0.1167386379652221 0.9070671709224832 1.0 1.0 58 Q4J6C6,Q9H4M9,O43752,Q9H4A6,Q15904,P51149,Q15334,P98194,O15027,Q92673,Q9H3S7,Q9H223,Q96L92 13 +Actin myosin filament sliding 0.4816008595218799 0.1153494546283367 0.9081681408072506 1.0 1.0 2 P09493 1 +Regulation of synaptic transmission glutamatergic 0.3748992206396115 0.1149454124629416 0.9084883896788344 1.0 1.0 4 Q00535,P19022,Q8NBU5 3 +Extrinsic apoptotic signaling pathway via death domain receptors 0.3228526852143055 0.1148732303334168 0.9085456037045314 1.0 1.0 17 Q99523 1 +Growth hormone secretion 0.4797206553854355 0.1134184966859207 0.9096987760951696 1.0 1.0 2 Q06124 1 +Neuron migration 0.314285326017899 0.1123674077288365 0.9105320964936948 1.0 1.0 27 Q9BVA1,Q92859,O15031,O94898,P46108,O14786 6 +Fibroblast growth factor receptor signaling pathway 0.3442711135018964 0.1113461736677531 0.9113418417278198 1.0 1.0 7 Q8NEM2,Q9Y639,Q06124,P61106,P46109,P35222 6 +Cellular response to leucine starvation 0.3719793622521929 0.1104352508090005 0.9120641979894122 1.0 1.0 4 Q9P2X3 1 +Neuroblast proliferation 0.3326481188512494 0.1089588705837563 0.913235112566476 1.0 1.0 12 O15031,Q9H0H5,Q8NCG7 3 +Response to dexamethasone 0.3394912178173342 0.1089466395682152 0.913244813753766 1.0 1.0 9 P04062 1 +Regulation of histone phosphorylation 0.3427350981233094 0.1071451025829656 0.9146738664003462 1.0 1.0 7 Q06787 1 +Inner ear receptor cell stereocilium organization 0.3526881720430035 0.1062345124015177 0.9153962889351852 1.0 1.0 5 Q15643,Q14160,O95487,Q9BW83 4 +Reactive oxygen species metabolic process 0.3118179397409437 0.1061200428360457 0.9154871090530632 1.0 1.0 47 P42785,Q9NRA0,P51790,Q13423,P04899 5 +Toll like receptor 9 signaling pathway 0.4721998388396461 0.1060916197019851 0.9155096601298702 1.0 1.0 2 Q9NQC3 1 +Positive regulation of toll like receptor 9 signaling pathway 0.4721998388396461 0.1060916197019851 0.9155096601298702 1.0 1.0 2 Q9NQC3 1 +Regulation of toll like receptor 9 signaling pathway 0.4721998388396461 0.1060916197019851 0.9155096601298702 1.0 1.0 2 Q9NQC3 1 +Negative regulation of alpha beta t cell differentiation 0.47219983883964 0.1060916197019795 0.9155096601298748 1.0 1.0 2 P04083 1 +Neutrophil homeostasis 0.47219983883964 0.1060916197019795 0.9155096601298748 1.0 1.0 2 P04083 1 +Negative regulation of cd4 positive alpha beta t cell differentiation 0.47219983883964 0.1060916197019795 0.9155096601298748 1.0 1.0 2 P04083 1 +Regulation of cd4 positive alpha beta t cell differentiation 0.47219983883964 0.1060916197019795 0.9155096601298748 1.0 1.0 2 P04083 1 +Neutrophil clearance 0.47219983883964 0.1060916197019795 0.9155096601298748 1.0 1.0 2 P04083 1 +Regulation of morphogenesis of an epithelium 0.4645410898497596 0.1052259086231666 0.916196552734539 1.0 1.0 3 P35222 1 +Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity 0.4711254364759611 0.1050958771641637 0.916299730734688 1.0 1.0 2 P42858 1 +Protein folding in endoplasmic reticulum 0.3364737550471124 0.1040135257067265 0.9171586148316168 1.0 1.0 10 P30101,P27797,P07237,Q13217,Q9P0L0,P14625,P27824,Q96HE7,Q8IXB1 9 +Positive regulation of torc1 signaling 0.4618484685652789 0.1022872249829602 0.9185286951074708 1.0 1.0 3 Q9P2J5,Q96EE3 2 +Nadh dehydrogenase complex assembly 0.3125907751716617 0.1013223883960314 0.9192945442792468 1.0 1.0 27 O43676,P51970,O96000,Q9Y6M9 4 +Positive regulation of calcium ion transport 0.3175543268370638 0.1003973403179471 0.9200288812183706 1.0 1.0 20 P42858,Q9NRA0,P16885,O76024,P54652,P30536,O14936,P20020,P0DP25,Q13586,P05026 11 +Dna ligation involved in dna repair 0.4562063406770454 0.0963817730750965 0.9232173677027168 1.0 1.0 3 Q96T60,Q13426 2 +Regulation of epithelial cell proliferation involved in lung morphogenesis 0.4601128122481757 0.0955984215788433 0.9238395188576248 1.0 1.0 2 P60953 1 +Positive regulation of epithelial cell proliferation involved in lung morphogenesis 0.4601128122481757 0.0955984215788433 0.9238395188576248 1.0 1.0 2 P60953 1 +Glycerophospholipid biosynthetic process 0.3101788197563729 0.0955659340345355 0.9238653220297448 1.0 1.0 54 Q8TCG2,Q9NYA4,Q9BTU6,Q5H8A4,Q9HCL2,Q13614,Q9NX62,Q9UG56,O15228,O00459,Q96PE3,P35790 12 +Epithelial cell proliferation involved in lung morphogenesis 0.454862976894132 0.0950254604262871 0.9242946039276588 1.0 1.0 3 Q13247,P60953 2 +Rhythmic process 0.3028233163214367 0.0935342170410065 0.925479167567389 1.0 1.0 65 Q13185,P54802,Q9BWF3,O95470,O00429,O94813,Q14103,P29992,P19021,Q05086 10 +Regulation of fertilization 0.4574268063389743 0.0934723146551323 0.9255283430874428 1.0 1.0 2 Q9NVM9 1 +Histone h3 k9 modification 0.31797483341534 0.0927987953078705 0.9260634080873672 1.0 1.0 18 Q9H9B1,Q96KQ7 2 +Isocitrate metabolic process 0.3448618485044033 0.0904112047062429 0.9279604530920184 1.0 1.0 6 P48735 1 +Regulation of polysaccharide metabolic process 0.3445761723006925 0.0897795246914615 0.928462419400921 1.0 1.0 6 P31751 1 +Regulation of peptidyl lysine acetylation 0.3108341360990568 0.089452548022793 0.9287222635292114 1.0 1.0 24 Q9P265,Q9NRA0,Q969T9,Q01105,O75844,Q14012 6 +Cellular response to carbohydrate stimulus 0.3103180560063847 0.0889736723637505 0.9291028335287423 1.0 1.0 28 P62995,Q99808,Q5KU26,P17612,Q15043 5 +Negative regulation of kinase activity 0.3100026497047545 0.0886029772406062 0.929397441898036 1.0 1.0 50 P04062,Q92673,P10644 3 +Regulation of transporter activity 0.3085373666307824 0.0869006879052832 0.9307504527210652 1.0 1.0 56 P17252,Q9NRA0,P27105,Q04656,P0DP25,O00308,Q06787,P17612,P05026,P05067,P46934,O43865,P05556 13 +Regulation of calcium ion transport 0.3034055688597858 0.0851477451297207 0.9321439329768484 1.0 1.0 36 P21796,Q9NRA0,Q9UKS6,Q06787,O14936,P04899,P17612,P0DP25,P05026 9 +Negative regulation of autophagy of mitochondrion 0.4443847393874168 0.0850875610992418 0.9321917792477828 1.0 1.0 3 Q9NQ88,P30536 2 +Positive regulation of striated muscle cell apoptotic process 0.4443847393874159 0.085087561099241 0.9321917792477834 1.0 1.0 3 P17655,Q9NQ88 2 +Positive regulation of execution phase of apoptosis 0.4443847393874152 0.0850875610992404 0.9321917792477838 1.0 1.0 3 Q8IXJ6,P63167 2 +Attachment of mitotic spindle microtubules to kinetochore 0.3329790250483169 0.0833520799497334 0.933571590516779 1.0 1.0 8 Q9BZD4,Q96DB5,Q96EE3 3 +B cell receptor signaling pathway 0.442922374429223 0.0832043591117341 0.9336890466909684 1.0 1.0 2 P16885 1 +T helper cell lineage commitment 0.4426537738382928 0.083032724041144 0.9338255194245104 1.0 1.0 2 P42345 1 +Positive regulation of metallopeptidase activity 0.4426537738382895 0.083032724041142 0.933825519424512 1.0 1.0 2 Q96HY6 1 +Morphogenesis of embryonic epithelium 0.3072429236986461 0.0823074079584182 0.934402263711624 1.0 1.0 31 O14641,P11233,O15031,P22694,Q13308,P17612,P98164 7 +Interleukin 23 production 0.4405049691109313 0.081682847157225 0.9348989187589556 1.0 1.0 2 P16885 1 +Engulfment of apoptotic cell 0.4405049691109182 0.0816828471572172 0.9348989187589618 1.0 1.0 2 P84095 1 +Positive regulation of centriole replication 0.4402363685199971 0.0815169921792569 0.9350308120444764 1.0 1.0 2 O75351 1 +Regulation of tooth mineralization 0.4388933655654027 0.0806972185167851 0.9356827489059788 1.0 1.0 2 P04920 1 +Negative regulation of ossification 0.4390112842557652 0.0804209945364345 0.935902429757674 1.0 1.0 3 P22413,Q06330 2 +Rrna pseudouridine synthesis 0.3320541265524592 0.0791119436801693 0.9369435836073828 1.0 1.0 7 Q9NPE3,Q96HR8 2 +Telencephalon glial cell migration 0.331432271951551 0.079027493074329 0.9370107551344952 1.0 1.0 8 P07942,P35222,Q96N66 3 +Cerebral cortex radially oriented cell migration 0.331432271951551 0.079027493074329 0.9370107551344952 1.0 1.0 8 P07942,P35222,Q96N66 3 +Endoplasmic reticulum plasma membrane tethering 0.4363245566899404 0.078193714189194 0.9376739620601398 1.0 1.0 3 A0FGR8,O95292 2 +Endoplasmic reticulum localization 0.4363245566899404 0.078193714189194 0.9376739620601398 1.0 1.0 3 A0FGR8,O95292 2 +Trna threonylcarbamoyladenosine metabolic process 0.3474872346143439 0.0773789403128371 0.9383220937403632 1.0 1.0 4 Q9Y606,Q7L0Y3,Q32P41 3 +Mitochondrial rna modification 0.3474872346143439 0.0773789403128371 0.9383220937403632 1.0 1.0 4 Q9Y606,Q7L0Y3,Q32P41 3 +Positive regulation of apoptotic signaling pathway 0.3012558797224305 0.0758179750549103 0.9395639152604592 1.0 1.0 35 P53634 1 +Positive regulation of muscle cell differentiation 0.3285297105362957 0.0748283385021977 0.940351294155704 1.0 1.0 9 Q14012,Q9BWF3,Q13049 3 +Regulation of nucleotide metabolic process 0.3115306112759357 0.0747899115639075 0.9403818687427836 1.0 1.0 21 P05067 1 +Ectoderm development 0.4312197743148738 0.0741520376869534 0.9408894091085672 1.0 1.0 3 Q9HCM4,P35222 2 +Fc epsilon receptor signaling pathway 0.43068242880171 0.0737408668302505 0.9412165802621107 1.0 1.0 3 P16885,P19174 2 +Regulation of postsynapse organization 0.3143553211774027 0.0730435004027668 0.9417715016245642 1.0 1.0 17 Q15375,Q9UQB8,Q05086 3 +Caveolin mediated endocytosis 0.3415748454716455 0.0706408820639895 0.9436835724853376 1.0 1.0 4 P28482,Q13432,Q9UNF0 3 +Trachea morphogenesis 0.3415748454716437 0.0706408820639875 0.9436835724853392 1.0 1.0 4 P28482,P35222,Q02750 3 +Trachea formation 0.3415748454716437 0.0706408820639875 0.9436835724853392 1.0 1.0 4 P28482,P35222,Q02750 3 +Trachea development 0.3415748454716437 0.0706408820639875 0.9436835724853392 1.0 1.0 4 P28482,P35222,Q02750 3 +Constitutive secretory pathway 0.4258463191832264 0.0701601277711351 0.9440662095148298 1.0 1.0 3 Q8TBQ9,Q9H082 2 +Negative regulation of cell substrate adhesion 0.3212786526228649 0.0701496099209211 0.9440745809189665 1.0 1.0 13 O14936 1 +Modification of postsynaptic actin cytoskeleton 0.341037355549585 0.0700514364233605 0.9441527198103484 1.0 1.0 4 P35080,Q7L576,Q9UQB8 3 +Pigment cell differentiation 0.32757925156807 0.0684535346526133 0.9454246072414448 1.0 1.0 8 P22413,P29992,Q86YV9 3 +Cell proliferation in forebrain 0.331182795698923 0.068284672754792 0.9455590250182452 1.0 1.0 5 Q96N67,Q15058,Q15154,Q9NZI8 4 +Cardiolipin acyl chain remodeling 0.4139135106097243 0.0681224780674716 0.9456881370085546 1.0 1.0 2 Q6UWP7 1 +Negative regulation of oligodendrocyte differentiation 0.4217271567180829 0.0672769701424022 0.9463612105063663 1.0 1.0 3 Q9Y2Y6 1 +Branched chain amino acid biosynthetic process 0.4193981730252435 0.0657130714743633 0.9476062653770329 1.0 1.0 3 O15382,P54687 2 +Genitalia morphogenesis 0.4053182917002369 0.0648445164029185 0.9482977970470694 1.0 1.0 2 P35222 1 +Protein processing involved in protein targeting to mitochondrion 0.4175174637291672 0.0644844597695298 0.9485844806641012 1.0 1.0 3 Q99797,Q10713 2 +Pons development 0.416711445459419 0.0639671778884169 0.9489963615142548 1.0 1.0 3 Q14160,O14949 2 +Cell junction organization 0.3832808640712757 0.0639276509467066 0.9490278350330597 1.0 1.0 150 Q9Y6W5,P19022,Q16625,Q13614,O75955,Q14118,Q5T2T1,P05067,Q9Y624,Q99538,P17301,Q9Y2Q5,O15031,Q9BQT9,P17612,Q14012,O60716,Q13641,P56545,P29317,P10586,Q9Y4F1,O95819,O14786,P41440,P46934,Q14126,P17252,Q96J84,Q9UQB8,O00192,Q6IQ23,Q12959,Q15375,O15228,P07437,O00560,Q9H3S7,P78310,Q05086 40 +Positive regulation of calcium ion transmembrane transporter activity 0.3229260205949307 0.0638416354759624 0.9490963255430702 1.0 1.0 11 P42858,P16885,P54652,P0DP25,Q13586,P05026 6 +Regulation of t cell differentiation in thymus 0.4023636852001026 0.0638263690741709 0.9491084815775296 1.0 1.0 2 O96005 1 +Regulation of receptor signaling pathway via stat 0.3238223418573334 0.0623233782415699 0.950305311518101 1.0 1.0 10 Q13043,Q00535,P30153,Q9NX40,Q8WXW3,P35240,Q6IA86,Q9H490,O14964 9 +Positive regulation of golgi to plasma membrane protein transport 0.4135893916905668 0.0620152774121614 0.9505506658033792 1.0 1.0 3 P98194 1 +Neuronal stem cell population maintenance 0.3312718472707651 0.0619245975489835 0.9506228790736108 1.0 1.0 6 Q9BXP5,Q9BXW9,P19022,Q15154,Q9NZI8 5 +Positive regulation of protein polyubiquitination 0.3331524078416251 0.0618376897607596 0.950692088817486 1.0 1.0 4 O00571 1 +Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization 0.3956486704270786 0.0617047472339578 0.950797959429847 1.0 1.0 2 O95140 1 +Negative regulation of cell size 0.3889336556540376 0.059832693256659 0.9522888867588976 1.0 1.0 2 P42345 1 +Male meiosis i 0.3840988450174627 0.0586274645261144 0.9532488347736652 1.0 1.0 2 P54652 1 +Negative regulation of defense response to bacterium 0.3832930432446988 0.0584375643530482 0.9534000938565754 1.0 1.0 2 Q8IXJ6 1 +Regulation of defense response to bacterium 0.3832930432446988 0.0584375643530482 0.9534000938565754 1.0 1.0 2 Q8IXJ6 1 +Negative regulation of type 2 immune response 0.383293043244696 0.0584375643530476 0.953400093856576 1.0 1.0 2 P04083 1 +Type 2 immune response 0.383293043244696 0.0584375643530476 0.953400093856576 1.0 1.0 2 P04083 1 +Response to oxygen radical 0.3241531015996407 0.0574958523827022 0.9541502099642236 1.0 1.0 5 Q04656 1 +Cellular response to oxygen radical 0.3241531015996407 0.0574958523827022 0.9541502099642236 1.0 1.0 5 Q04656 1 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.3225639302128852 0.0559762943623103 0.9553606919031707 1.0 1.0 7 P14174 1 +Purine deoxyribonucleoside triphosphate metabolic process 0.4024717893605513 0.0557081035878105 0.9555743438001992 1.0 1.0 3 Q9Y3Z3,P55263 2 +Positive regulation of heart rate 0.402471789360547 0.055708103587808 0.9555743438002012 1.0 1.0 3 P09493,P16615 2 +Cellular response to biotic stimulus 0.3033713750024035 0.05553536019263 0.9557119600462978 1.0 1.0 41 Q04721,P14174,O43823,O75844,Q8WTV0,Q9UBC1 6 +Negative regulation of histone h4 acetylation 0.3679828095621854 0.0553684348569279 0.9558449425821962 1.0 1.0 2 Q13363 1 +Peptidyl lysine deacetylation 0.3679828095621854 0.0553684348569279 0.9558449425821962 1.0 1.0 2 Q8IXJ6 1 +Macrophage cytokine production 0.3679828095621811 0.0553684348569273 0.9558449425821968 1.0 1.0 2 P16885 1 +Positive regulation of macrophage cytokine production 0.3679828095621811 0.0553684348569273 0.9558449425821968 1.0 1.0 2 P16885 1 +Negative regulation of protein exit from endoplasmic reticulum 0.4007411231186097 0.0548129371533412 0.956287493540492 1.0 1.0 3 Q13438 1 +Positive regulation of translation in response to endoplasmic reticulum stress 0.3975280014329106 0.0532101832692 0.9575644420357408 1.0 1.0 3 O00571 1 +Negative regulation of arp2 3 complex mediated actin nucleation 0.3965609887157318 0.0527426287287574 0.9579369734599104 1.0 1.0 3 P60983,O75146 2 +Negative regulation of actin nucleation 0.3965609887157318 0.0527426287287574 0.9579369734599104 1.0 1.0 3 P60983,O75146 2 +Cardiolipin metabolic process 0.3211403980634763 0.0526526084173038 0.958008699614214 1.0 1.0 7 Q9UJZ1,P40939,Q6UWP7,Q32NB8,Q96BW9,Q99623 6 +Mitotic nuclear membrane disassembly 0.3962923159591527 0.052613924466108 0.958039522218715 1.0 1.0 3 P53350,P17252 2 +Regulation of cellular ketone metabolic process 0.3041798096559291 0.0522247402656032 0.9583496199476882 1.0 1.0 23 Q2T9J0,Q06481 2 +Regulation of xenophagy 0.3413913510609775 0.051993612544484 0.958533782982676 1.0 1.0 2 Q96EP0 1 +Retina layer formation 0.3365565404243943 0.0515825064252886 0.9588613586316072 1.0 1.0 2 O75147 1 +Glucocorticoid metabolic process 0.3208814834721807 0.050613628085525 0.9596334031029672 1.0 1.0 4 Q9UNE7,P05023,Q04917 3 +Regulation of potassium ion import 0.3188183662806574 0.0498314524772514 0.9602567023579256 1.0 1.0 5 P05026 1 +Positive regulation of neuroblast proliferation 0.2790760139672353 0.0493446154783909 0.9606446647911716 1.0 1.0 2 P35222 1 +Regulation of adherens junction organization 0.3890381515314255 0.049331151016961 0.9606553948094668 1.0 1.0 3 P35611,Q9H3S7 2 +Renal vesicle development 0.2726295997851237 0.0492682664946987 0.96070550846222 1.0 1.0 2 P35222 1 +Mesenchymal to epithelial transition involved in metanephros morphogenesis 0.2726295997851237 0.0492682664946987 0.96070550846222 1.0 1.0 2 P35222 1 +Metanephric nephron morphogenesis 0.2726295997851237 0.0492682664946987 0.96070550846222 1.0 1.0 2 P35222 1 +Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 0.2726295997851237 0.0492682664946987 0.96070550846222 1.0 1.0 2 P35222 1 +Positive regulation of mesenchymal cell proliferation 0.2726295997851237 0.0492682664946987 0.96070550846222 1.0 1.0 2 P35222 1 +Metanephric renal vesicle morphogenesis 0.2726295997851237 0.0492682664946987 0.96070550846222 1.0 1.0 2 P35222 1 +Response to extracellular stimulus 0.3275733407877111 0.0489240158574627 0.9609798498894864 1.0 1.0 105 P17301,P01130,Q9H773,O95831,P80303,Q96QD8,P13473,Q92673,P02786,Q06481,P04062,P04899,P11166,Q96KQ7 14 +Regulation of ion transmembrane transport 0.2914302179054917 0.0485193620523366 0.9613023339268484 1.0 1.0 71 P21796,P17252,Q9NRA0,P27105,Q4KMQ2,P0DP25,Q04656,O00308,O75844,Q06787,P17612,P05026,P05067,P46934,O43865,P05556 16 +Positive regulation of mitophagy in response to mitochondrial depolarization 0.317119054017735 0.04753524297995 0.9620866422359522 1.0 1.0 4 Q16543,O95140,Q709C8 3 +Cellular response to organic cyclic compound 0.362995165002699 0.0471196413055256 0.9624178732252764 1.0 1.0 134 Q13185,Q9NUD5,Q9P1Z2,O15173,Q5KU26,O75955,Q14118,Q9H270,P00533,P63096,Q14103,P05067,P17301,Q969T9,O60266,P17612,Q9P2X3,Q13772,P29992,Q96KQ7,P08754,P09471,P46934,O95831,Q92542,P41440,O15118,Q05086 28 +Regulation of cd4 positive alpha beta t cell activation 0.3833960236431946 0.0470237801272294 0.9624942746893684 1.0 1.0 3 P04083,P09429 2 +Negative regulation of cd4 positive alpha beta t cell activation 0.3833960236431946 0.0470237801272294 0.9624942746893684 1.0 1.0 3 P04083,P09429 2 +Chemokine c c motif ligand 5 production 0.3833960236431932 0.0470237801272288 0.962494274689369 1.0 1.0 3 Q7Z434,O00571 2 +Regulation of transcription from rna polymerase ii promoter in response to hypoxia 0.3152378392905075 0.0460575150898749 0.9632644080958176 1.0 1.0 4 Q06330,Q8IXJ6,P04637 3 +Positive regulation of endothelial cell proliferation 0.3132188330228177 0.0448354050964057 0.9642385042713244 1.0 1.0 14 O14786 1 +Positive regulation of striated muscle cell differentiation 0.3134494912085062 0.0446900713900668 0.9643543476756458 1.0 1.0 4 Q13049 1 +Histone h4 deacetylation 0.3145161290322533 0.0439749201159056 0.9649243953711018 1.0 1.0 5 Q13547,Q9UKL0,Q92769,Q8IXJ6 4 +Pyrimidine containing compound metabolic process 0.2996672938138867 0.0435790484380445 0.965239952753028 1.0 1.0 33 Q9H773 1 +Trna thio modification 0.3737238044062267 0.0435324404811474 0.965277105264456 1.0 1.0 3 Q2VPK5,O95396 2 +Positive regulation of actin filament polymerization 0.3142950052285665 0.0431902882751911 0.9655498466998388 1.0 1.0 13 P62993,Q96J84,Q9UQB8,P42345,Q12959 5 +Steroid esterification 0.3705455058163101 0.0425049691044616 0.9660961505595678 1.0 1.0 3 P35610 1 +Cardiac cell development 0.3075732102489731 0.0420089446955729 0.9664915675772244 1.0 1.0 16 O75844 1 +Positive regulation of myeloid cell apoptotic process 0.3680816765179937 0.0417469466486868 0.966700428546626 1.0 1.0 3 P42771,P04083 2 +Regulation of unsaturated fatty acid biosynthetic process 0.3680816765179914 0.0417469466486859 0.9667004285466264 1.0 1.0 3 P04083,Q8WXW3 2 +Axoneme assembly 0.3669305931258362 0.0414040196529639 0.9669738083272096 1.0 1.0 3 A0AVF1 1 +Epigenetic maintenance of chromatin in transcription competent conformation 0.3155162644860549 0.0398997463713397 0.9681730533098688 1.0 1.0 7 Q9NRA0 1 +Intraciliary transport involved in cilium assembly 0.3557549086637616 0.0384244470517734 0.9693492694434178 1.0 1.0 3 A0AVF1 1 +Cochlea development 0.3185988557039055 0.0382584300219865 0.96948163453969 1.0 1.0 6 O14641 1 +Positive regulation of helicase activity 0.3036818059661296 0.0378423009749556 0.9698134172097648 1.0 1.0 4 Q04837,P20585,P52701 3 +Auditory receptor cell morphogenesis 0.3524986566362072 0.0376680443554095 0.9699523548161272 1.0 1.0 3 Q14160,O95487 2 +Skeletal muscle acetylcholine gated channel clustering 0.3007256113947836 0.0359688974014538 0.9713071591768208 1.0 1.0 4 P46109,Q14696,O15258 3 +Endoplasmic reticulum to golgi vesicle mediated transport 0.290083152017179 0.033856162511194 0.9729918503785588 1.0 1.0 71 Q9BVK6,Q9P2W9,Q9Y282,Q96PC5,Q8NHH9,Q13190,O15027,O95249,Q9UHQ4,Q92673,P24390,Q9NR31,P51809,Q969X5,Q9NZ43,Q9H0U4 16 +Negative regulation of locomotion 0.3036149465787557 0.0337029936825924 0.973113991716803 1.0 1.0 52 Q96G23,P14174,O94813,Q14118,O14786,Q07954,P51805,Q9Y6N7 8 +Mature ribosome assembly 0.3046556969866711 0.0316234561947973 0.974772337404164 1.0 1.0 5 Q07021 1 +Negative regulation of type i interferon mediated signaling pathway 0.3116603976356717 0.0315052816713872 0.9748665800726952 1.0 1.0 3 P55265,Q9Y3Z3 2 +Histone h3 deacetylation 0.314600699112661 0.0313730226477934 0.974972055365728 1.0 1.0 6 Q8IXJ6,P23246,Q92769,Q13547,Q96EB6 5 +Hemoglobin metabolic process 0.2987641053197095 0.0305019359498032 0.9756667494362156 1.0 1.0 3 Q86U70,Q9NRK6 2 +Hemoglobin biosynthetic process 0.2987641053197095 0.0305019359498032 0.9756667494362156 1.0 1.0 3 Q86U70,Q9NRK6 2 +Regulation of hemoglobin biosynthetic process 0.2987641053197095 0.0305019359498032 0.9756667494362156 1.0 1.0 3 Q86U70,Q9NRK6 2 +Erythrocyte maturation 0.2958087049972989 0.0303161242354078 0.9758149372030044 1.0 1.0 3 P11413,P18074 2 +Metanephric nephron development 0.2727028479312105 0.0292948459204504 0.97662943749948 1.0 1.0 3 P11047,P35222 2 +Serine family amino acid catabolic process 0.2595378828586678 0.0289660082688184 0.9768917006840564 1.0 1.0 3 P23378,P34897 2 +Positive regulation of cholesterol biosynthetic process 0.2514777001611917 0.0288259329431884 0.9770034179732072 1.0 1.0 3 Q12770,P16435 2 +Positive regulation of cholesterol metabolic process 0.2514777001611917 0.0288259329431884 0.9770034179732072 1.0 1.0 3 Q12770,P16435 2 +Positive regulation of alcohol biosynthetic process 0.2514777001611917 0.0288259329431884 0.9770034179732072 1.0 1.0 3 Q12770,P16435 2 +Regulation of mitotic cytokinesis 0.2447608812466313 0.0287363969520996 0.9770748277756338 1.0 1.0 3 P37198,Q9Y2S7 2 +Cardiac muscle cell differentiation 0.3046368346462031 0.0286707194603226 0.9771272092494628 1.0 1.0 19 O75844,P78310 2 +Regulation of early endosome to late endosome transport 0.3103554949705677 0.0284701136459485 0.9772872042185208 1.0 1.0 13 Q9H270,Q9Y3E7,Q13614 3 +Rna capping 0.3018817204301048 0.0284120077486164 0.9773335472697896 1.0 1.0 5 Q53F19,Q96RS0,Q09161,O43148 4 +Wound healing spreading of epidermal cells 0.3016129032257977 0.0281068321390566 0.9775769449685708 1.0 1.0 5 Q92766,Q96AC1,P42345,O75122 4 +Regulation of wound healing spreading of epidermal cells 0.3016129032257977 0.0281068321390566 0.9775769449685708 1.0 1.0 5 Q92766,Q96AC1,P42345,O75122 4 +Regulation of type i interferon mediated signaling pathway 0.3122476446837043 0.0270491892355623 0.9784205010299312 1.0 1.0 10 P08238,P55265,Q7Z434,Q9Y3Z3,P61086,Q06124,P18031,Q9NZI8,Q16543 9 +Ether biosynthetic process 0.2998589072569875 0.0261415909116133 0.9791444036364036 1.0 1.0 5 O00116 1 +Negative regulation of cell substrate junction organization 0.2978494623655876 0.0239451727435525 0.9808963419611384 1.0 1.0 5 P63167,Q9ULV4,Q9H6U6,O75122 4 +Positive regulation of neuron differentiation 0.3105143963467513 0.0229700084272097 0.981674196442597 1.0 1.0 11 Q8WUJ1,Q13049 2 +Muscle cell development 0.2965500572903303 0.021342428465004 0.9829724985165798 1.0 1.0 33 O75844,P10644,P05556,P78310 4 +Gastrulation 0.2975893713081241 0.0210970449409665 0.9831682421669784 1.0 1.0 39 P17301,P06756,O14641,P29317,P10644,Q14118,Q9Y2G5,P05556 8 +Negative regulation of stress activated protein kinase signaling cascade 0.3086788474171391 0.0209095554031564 0.9833178041818617 1.0 1.0 12 Q12959,O00255,P78318,Q96J02 4 +Snrna modification 0.2946236559139706 0.0205406935229842 0.9836120501788086 1.0 1.0 5 Q4G0J3,Q9NX24,Q7L2J0,Q9NPE3 4 +Layer formation in cerebral cortex 0.2645917316792054 0.019488708290105 0.9844512448130364 1.0 1.0 4 P35222 1 +Positive regulation of potassium ion transmembrane transporter activity 0.2915711776341304 0.0174549896064013 0.9860736404604586 1.0 1.0 5 P05026,P50570 2 +Gastrulation with mouth forming second 0.2576067096054301 0.0174525558699058 0.9860755820054804 1.0 1.0 4 P35222 1 +Positive regulation of steroid biosynthetic process 0.2515452835259293 0.0159265130821281 0.9872930183023552 1.0 1.0 4 Q12770,P08069,P16435 3 +Positive regulation of steroid metabolic process 0.2515452835259293 0.0159265130821281 0.9872930183023552 1.0 1.0 4 Q12770,P08069,P16435 3 +Establishment or maintenance of bipolar cell polarity 0.3018476124733844 0.0149962693839516 0.9880351566490572 1.0 1.0 19 Q14517,Q13418,Q14168,Q12959,Q13308,Q14160,Q96RT1 7 +Rna secondary structure unwinding 0.2424079548508407 0.0140029240379389 0.9888276482211862 1.0 1.0 4 Q13838,Q08211,O00571 3 +Ribonucleoprotein complex disassembly 0.2402579951625859 0.0136100685642987 0.9891410716625068 1.0 1.0 4 P33176,P55072,Q07866 3 +Sequestering of triglyceride 0.2238645525396395 0.0112484256008945 0.9910252441383788 1.0 1.0 4 Q9BZF1,P22413,Q9BXB4 3 +Centriole centriole cohesion 0.2849462365591351 0.0112012834365761 0.99106285577389 1.0 1.0 5 Q9BV73,Q14203,P35222,Q9C0F1 4 +Pattern specification process 0.3009433443885322 0.0105434029102191 0.9915877374557748 1.0 1.0 50 Q04721,O14965,P62995,O14641,Q9Y6N7,Q7Z4L5,O75787,P22694,P17612,O14786,Q9Y673,P98164 12 +Regulation of rna export from nucleus 0.3055026273184905 0.0078216692025938 0.9937592745366546 1.0 1.0 10 Q07666,Q08J23 2 +Regulation of protein export from nucleus 0.2999308683257639 0.0059483672231876 0.9952539176191456 1.0 1.0 17 P17612,Q99728,Q14012,P50402 4 +Protein import 0.3043458987174827 0.0053955403270908 0.9956950025635788 1.0 1.0 90 Q99595,Q13501,Q9NS69,P13473,Q06481 5 +Axo dendritic transport 0.2972616393232252 0.0050428614261916 0.9959763957794592 1.0 1.0 28 Q14168,P05067 2 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a56f985ab579dabc8415252770bb6e0400b7f444 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Acrosome reaction", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of janus kinase activity", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activation of store operated calcium channel activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine catabolic process", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in coronary vascular morphogenesis", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Arterial endothelial cell differentiation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular node development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon choice point recognition", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axon midline choice point recognition", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Bile acid signaling pathway", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brain renin angiotensin system", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in salivary gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bud elongation involved in lung branching", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Cadmium ion transmembrane transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into cytosol", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp biosynthetic process", "Camp catabolic process", "Camp mediated signaling", "Camp metabolic process", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in cardiac muscle cell fate commitment", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac cell fate commitment", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell fate commitment", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell myoblast differentiation", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac muscle tissue regeneration", "Cardiac myofibril assembly", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cholesterol", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nicotine", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to progesterone stimulus", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide 1 phosphate transport", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chiasma assembly", "Chitin metabolic process", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chorionic trophoblast cell differentiation", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen activated signaling pathway", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Commissural neuron axon guidance", "Common bile duct development", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Convergent extension involved in gastrulation", "Convergent extension involved in organogenesis", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion import", "Copper ion transmembrane transport", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial nerve morphogenesis", "Cranial nerve structural organization", "Cranial skeletal system development", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide biosynthetic process", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of light stimulus involved in sensory perception", "Detection of mechanical stimulus", "Detection of mechanical stimulus involved in sensory perception", "Detection of mechanical stimulus involved in sensory perception of pain", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of stimulus involved in sensory perception", "Detection of stimulus involved in sensory perception of pain", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Dichotomous subdivision of an epithelial terminal unit", "Dichotomous subdivision of terminal units involved in salivary gland branching", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Direct ossification", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal aorta development", "Dorsal aorta morphogenesis", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Drinking behavior", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Elastic fiber assembly", "Elastin catabolic process", "Elastin metabolic process", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardial cushion development", "Endocardial cushion formation", "Endocardial cushion morphogenesis", "Endocardium development", "Endocardium morphogenesis", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial to mesenchymal transition involved in endocardial cushion formation", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facial nerve morphogenesis", "Facial nerve structural organization", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin biosynthetic process", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain dorsal ventral pattern formation", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G1 to g0 transition involved in cell differentiation", "G2 mi transition of meiotic cell cycle", "Galactolipid biosynthetic process", "Galactolipid metabolic process", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastric acid secretion", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glomerulus morphogenesis", "Glomerulus vasculature morphogenesis", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Hard palate development", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Heparin biosynthetic process", "Heparin metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 demethylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus cell migration", "Hypothalamus development", "Hypothalamus gonadotrophin releasing hormone neuron differentiation", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid catabolic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Induction of positive chemotaxis", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell fate commitment", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate biosynthetic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Inositol trisphosphate biosynthetic process", "Inositol trisphosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 mediated signaling pathway", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal epithelial structure maintenance", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Iodide transport", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isg15 protein conjugation", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lacrimal gland development", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral mesoderm development", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens fiber cell morphogenesis", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene d4 metabolic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Ligand gated ion channel signaling pathway", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung growth", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteinizing hormone secretion", "Luteolysis", "Lymph vessel development", "Lymph vessel morphogenesis", "Lymphangiogenesis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage activation involved in immune response", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of animal organ identity", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Marginal zone b cell differentiation", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Melanosome assembly", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane fusion involved in viral entry into host cell", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Menaquinone metabolic process", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesendoderm development", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microtubule severing", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Motor neuron migration", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multinuclear osteoclast differentiation", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell fate commitment", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myd88 independent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immune response to tumor cell", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic process involved in development", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte activation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of atpase coupled calcium transmembrane transporter activity", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axon extension involved in axon guidance", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of behavior", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of camp mediated signaling", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cardiocyte differentiation", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular amine metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular extravasation", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular response to vascular endothelial growth factor stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of ceramide biosynthetic process", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of feeding behavior", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of g0 to g1 transition", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of granulocyte differentiation", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 beta production", "Negative regulation of interleukin 1 production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein metabolic process", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of long term synaptic potentiation", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage activation", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage derived foam cell differentiation", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microglial cell activation", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell activation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuroinflammatory response", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil activation", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nlrp3 inflammasome complex assembly", "Negative regulation of non canonical wnt signaling pathway", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of pathway restricted smad protein phosphorylation", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl cysteine s nitrosylation", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of smad protein signal transduction", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sphingolipid biosynthetic process", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of torc1 signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of triglyceride catabolic process", "Negative regulation of triglyceride metabolic process", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest cell migration involved in autonomic nervous system development", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Norepinephrine metabolic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Notochord development", "Notochord morphogenesis", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast development", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Osteoclast fusion", "Otic vesicle development", "Otic vesicle formation", "Otic vesicle morphogenesis", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Outflow tract septum morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parasympathetic nervous system development", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericardium development", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Peristalsis", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phasic smooth muscle contraction", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Piecemeal microautophagy of the nucleus", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyamine transmembrane transport", "Polyamine transport", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alkaline phosphatase activity", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagosome maturation", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axon extension involved in axon guidance", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of bicellular tight junction assembly", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardiac muscle contraction", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion mediated by integrin", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cell adhesion mediated by integrin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell proliferation involved in heart morphogenesis", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of enamel mineralization", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gap junction assembly", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 13 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 23 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term neuronal synaptic plasticity", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immune response to tumor cell", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide mediated signal transduction", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of osteoclast differentiation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phospholipid translocation", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of platelet derived growth factor receptor signaling pathway", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein kinase c signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein localization to synapse", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell population maintenance", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of store operated calcium channel activity", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 2 signaling pathway", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tooth mineralization", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Proline transmembrane transport", "Proline transport", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c activating g protein coupled receptor signaling pathway", "Protein kinase c signaling", "Protein linear polyubiquitination", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to non motile cilium", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to site of double strand break", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein palmitoylation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide catabolic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor mediated virion attachment to host cell", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reduction of food intake in response to dietary excess", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adiponectin secretion", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alkaline phosphatase activity", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte activation", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagic cell death", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of bile acid secretion", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of blood vessel remodeling", "Regulation of blood volume by renin angiotensin", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching involved in ureteric bud morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cdc42 protein signal transduction", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centromere complex assembly", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of development heterochronic", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of eating behavior", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of enamel mineralization", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endosome to plasma membrane protein transport", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gap junction assembly", "Regulation of gastric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of growth rate", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart morphogenesis", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homophilic cell adhesion", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of inflammatory response to wounding", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphangiogenesis", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage derived foam cell differentiation", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of melanocyte differentiation", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immune response to tumor cell", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter receptor localization to postsynaptic specialization membrane", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil activation", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil degranulation", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non canonical wnt signaling pathway", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast development", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl cysteine s nitrosylation", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigment cell differentiation", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of positive chemotaxis", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic cytosolic calcium ion concentration", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor activity", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of somitogenesis", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of store operated calcium entry", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle cycle", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 2 signaling pathway", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription from rna polymerase ii promoter involved in heart development", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type b pancreatic cell proliferation", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wnt signaling pathway involved in heart development", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system vasculature development", "Renal system vasculature morphogenesis", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cycloheximide", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoprotein", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to herbicide", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to inactivity", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 17", "Response to interleukin 2", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle inactivity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to stimulus involved in regulation of muscle adaptation", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin e", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Sebaceous gland development", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary heart field specification", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secondary palate development", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of chemical stimulus", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory perception of smell", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal complex assembly", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Store operated calcium entry", "Strand invasion", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfation", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic assembly at neuromuscular junction", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 2 signaling pathway", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Trans synaptic signaling modulating synaptic transmission", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription factor catabolic process", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Trigeminal ganglion development", "Trigeminal nerve development", "Trigeminal nerve morphogenesis", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type b pancreatic cell proliferation", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent glycoprotein erad pathway", "Ubiquitin dependent protein catabolic process via the c end degron rule pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urate transport", "Urea cycle", "Urea metabolic process", "Ureter development", "Urinary bladder smooth muscle contraction", "Urinary tract smooth muscle contraction", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Vestibulocochlear nerve development", "Vestibulocochlear nerve morphogenesis", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion import across plasma membrane", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACE2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADAT3", "ADCY3", "ADD1", "ADD2", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALG9", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APIP", "APLP2", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARID4B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASNSD1", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATM", "ATP11C", "ATP13A1", "ATP13A2", "ATP13A3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATRN", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BANP", "BAP1", "BAP18", "BARD1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT1", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BEND3", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BSG", "BTAF1", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf57", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C21orf59", "C2CD5", "C2orf49", "C3orf58", "C5orf51", "CAB39", "CABIN1", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CAMK1", "CAMK2G", "CAMLG", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CASP8AP2", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX4", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCNB1", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD109", "CD276", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK7", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPI", "CENPU", "CENPV", "CEP250", "CEP290", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLK2", "CLK3", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT9", "CNP", "CNPY2", "COA3", "COASY", "COCH", "COG3", "COG4", "COG7", "COG8", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPE", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CREG1", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTBS", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DMD", "DMXL1", "DMXL2", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNASE2", "DNM1", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4ENIF1", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENPP4", "ENTPD7", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM105A", "FAM120B", "FAM162A", "FAM192A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM83D", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FAT1", "FBL", "FBXO21", "FBXO22", "FBXO38", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1", "FNDC3A", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FREM2", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALE", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GGT7", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GIT1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRAMD1A", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK2", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JAK1", "JCAD", "JUP", "KANK2", "KARS", "KAT5", "KAT7", "KATNA1", "KCTD10", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFAP3", "KIFBP", "KIFC1", "KIN", "KIRREL1", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDB1", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN2", "LMAN2L", "LMF2", "LMNA", "LMNB1", "LMO7", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRIG1", "LRIG2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRR1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYSMD3", "LZTFL1", "M6PR", "MACF1", "MACROD1", "MAD2L1BP", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4", "MAP4K4", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBLAC2", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED27", "MEN1", "MEPCE", "MESD", "METAP2", "METTL13", "METTL15", "METTL17", "METTL7B", "MFAP1", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGA", "MGAT2", "MGEA5", "MGRN1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKL2", "MKRN2", "MLEC", "MMAB", "MMADHC", "MMGT1", "MMS19", "MMS22L", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRC2", "MRE11", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL20", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS24", "MRPS27", "MRPS28", "MRPS30", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTFR1", "MTFR1L", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA4", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NEO1", "NEPRO", "NES", "NEU1", "NF1", "NF2", "NFATC2IP", "NFKBIL1", "NFRKB", "NFS1", "NFU1", "NHP2", "NID1", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME4", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "OAT", "OBSL1", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC1", "ORC2", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSTM1", "OTUB1", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PAM", "PAN2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4K2B", "PI4KA", "PI4KB", "PIAS1", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGO", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLEKHA7", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNMA1", "PNN", "PNP", "PNPLA6", "PNPT1", "PODXL", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKACB", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB31", "RAB32", "RAB33B", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1CC1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMI1", "RMND1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF149", "RNF20", "RNF213", "RNF219", "RNF31", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCAMP4", "SCAP", "SCARA3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL1", "SCYL2", "SDAD1", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SELENOI", "SENP3", "SENP6", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGSH", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIAE", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG6", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMPDL3A", "SMPDL3B", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX25", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORL1", "SORT1", "SPAG9", "SPART", "SPATA5", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPHK2", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR3", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STK3", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYDE1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TAX1BP1", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TCTN3", "TDRD7", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX2", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "TGS1", "THADA", "THAP11", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIPRL", "TJP1", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM11", "TMEM115", "TMEM126B", "TMEM14C", "TMEM167A", "TMEM199", "TMEM201", "TMEM206", "TMEM214", "TMEM230", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMEM98", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIO", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2B", "TRMT5", "TRMT6", "TRMU", "TROVE2", "TRPC4AP", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TSR3", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC39C", "TTC4", "TTF2", "TTK", "TTLL12", "TTLL4", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP1", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "URGCP", "UROD", "USE1", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP32", "USP33", "USP34", "USP36", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAC14", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VLDLR", "VMP1", "VPS11", "VPS13A", "VPS13C", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "VTI1B", "WAPL", "WARS", "WASF2", "WASHC3", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR70", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WLS", "WNK1", "WNK2", "WRN", "WRNIP1", "WTAP", "WWP2", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF131", "ZNF277", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF598", "ZNF622", "ZNF638", "ZNF830", "ZPR1", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCD4", "ABHD12", "ABI1", "ACOT8", "ACOX3", "ACP2", "ACTN4", "ADAR", "ADCY3", "ADD1", "ADGRE5", "ADK", "ADPGK", "AGPS", "AHCYL1", "AIFM1", "AIP", "AKAP8", "AKT2", "ALCAM", "ALG11", "ALG5", "ALKBH5", "AMOT", "AMPD2", "ANK3", "ANKFY1", "ANKLE2", "ANO6", "ANXA1", "ANXA3", "APBB1", "APEX1", "APLP2", "APOL2", "APP", "APRT", "ARCN1", "ARFIP2", "ARIH1", "ARV1", "ARVCF", "ASAH1", "ASNA1", "ASPH", "ATAD1", "ATG7", "ATG9A", "ATL2", "ATP13A1", "ATP13A2", "ATP13A3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP7A", "ATPIF1", "ATRN", "AURKA", "B3GAT3", "B4GALT3", "B4GAT1", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BANP", "BAP1", "BARD1", "BCAP29", "BCAS3", "BCAT1", "BCAT2", "BRAP", "BRAT1", "BSG", "BTN2A1", "C12orf43", "C12orf73", "C1QBP", "C3orf58", "CADM1", "CALCOCO1", "CALCOCO2", "CALM3", "CALR", "CAMK1", "CANT1", "CANX", "CAPN2", "CAPZB", "CASK", "CBX3", "CCDC134", "CCDC47", "CCNB1", "CCNK", "CD109", "CD276", "CD2AP", "CD320", "CD47", "CDC37", "CDC42", "CDH2", "CDK4", "CDK5", "CDKN2A", "CELF1", "CEP250", "CEP44", "CERS1", "CERS2", "CHAC2", "CHEK1", "CHKA", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHPF2", "CHST14", "CIRBP", "CLASP2", "CLCN3", "CLCN7", "CLN5", "CLN6", "CLPP", "CLPTM1", "CLSTN3", "CNNM3", "CNNM4", "CNOT11", "CNP", "COA3", "COCH", "COLEC12", "COMT", "COPG1", "COQ8A", "CORO1B", "CORO1C", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2L", "CPD", "CPE", "CPT2", "CREG1", "CRK", "CRKL", "CRTAP", "CSGALNACT2", "CSNK2B", "CSRP2", "CTBP1", "CTBP2", "CTBS", "CTNNB1", "CTNND1", "CTSA", "CTSB", "CTSC", "CTSL", "CTTN", "CTU2", "CUTA", "CXADR", "CYB5B", "CYB5D2", "CYC1", "CYFIP1", "CYP51A1", "DAG1", "DAGLB", "DAXX", "DCTN1", "DCTPP1", "DDRGK1", "DDX39B", "DDX3X", "DDX5", "DHCR24", "DHCR7", "DHFR", "DHX9", "DIABLO", "DIP2B", "DLG1", "DNAJC1", "DNAJC10", "DNAJC3", "DNASE2", "DNM1L", "DNM2", "DOCK1", "DOCK7", "DOLPP1", "DPY30", "DSC3", "DSG2", "DVL2", "DYNLL1", "ECE1", "EGFR", "EHD1", "EHD4", "EHMT1", "EHMT2", "EIF2S1", "EIF4ENIF1", "ELP2", "EMD", "ENPP1", "ENPP4", "ENTPD7", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "ERBIN", "ERCC2", "ERGIC1", "ERGIC3", "ERO1A", "ESYT2", "EXO1", "F11R", "FAM120B", "FAM162A", "FAM3C", "FANCD2", "FARP1", "FAT1", "FBXO38", "FCGRT", "FDXR", "FECH", "FERMT2", "FIS1", "FKBP10", "FKBP14", "FKRP", "FLOT1", "FLOT2", "FMR1", "FREM2", "FTL", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G6PD", "GAA", "GABARAPL2", "GALNT1", "GALNT2", "GALNT7", "GBA", "GBE1", "GCLC", "GGH", "GGT7", "GINS4", "GIT1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GM2A", "GMFB", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNPAT", "GNS", "GOLM1", "GOLPH3", "GOSR1", "GOSR2", "GPAA1", "GPAM", "GPD2", "GPR107", "GPR108", "GRAMD1A", "GRB2", "GRSF1", "GTF3C1", "GUSB", "HADH", "HADHA", "HCCS", "HDAC1", "HDAC2", "HEXA", "HEXB", "HGS", "HIP1R", "HLA-A", "HLA-B", "HLA-C", "HMGB1", "HMGB2", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HOOK2", "HPRT1", "HPS6", "HS2ST1", "HSD17B12", "HSD17B7", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA2", "HTATIP2", "HTT", "ICMT", "IDH1", "IDH2", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2R", "ILK", "IMPACT", "IMPAD1", "INA", "INPP4A", "INTS13", "IQGAP3", "IRS4", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPK1", "IWS1", "JAGN1", "JAK1", "KAT7", "KDELR1", "KDM1B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KIDINS220", "KIF14", "KIF20A", "KIF23", "KIF5B", "KIRREL1", "KLC1", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LCLAT1", "LDB1", "LDLR", "LGALS3BP", "LGMN", "LIPA", "LLGL1", "LNPEP", "LRIG1", "LRIG2", "LRP1", "LRP2", "LRRC8A", "M6PR", "MAGED1", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MAP2K1", "MAP4K4", "MAPK1", "MAPRE2", "MAVS", "MBOAT7", "MCAM", "MCL1", "MCUB", "MED1", "MEN1", "MEPCE", "MESD", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD8", "MGAT2", "MGRN1", "MIA2", "MIF", "MINPP1", "MIPEP", "MMADHC", "MMGT1", "MOCS3", "MORF4L1", "MPP1", "MPP2", "MPP7", "MPV17L2", "MRC2", "MSH3", "MSH6", "MSMO1", "MSTO1", "MTMR2", "MTMR4", "MTOR", "NAA40", "NAF1", "NAGLU", "NAP1L1", "NAPA", "NAPG", "NCAM1", "NCBP1", "NCBP3", "NCOA4", "NCSTN", "NDC1", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS2", 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7.455308766626032 8.832436895439663 1.3320096182828691 0.3812427248674431 1.5026113775281769e-13 0.0185496530361188 2.876587777550066e-07 2.0421402838351183e-11 5.6314832815256263e-14 +Secretory granule membrane 29 86 3.914042266166319 9.07637374705228e-05 19.699029126213592 69.8495145631068 0.9295860214656708 0.3887665887416008 7.284889203542463 7.49087955205396 1.5950364553562375 0.3903287060113383 1.587407432956863e-11 0.0018512755404819 8.796288776465451e-06 5.8166865536755035e-11 2.9658409044240337e-11 +Azurophil granule lumen 18 47 3.834813310768189 0.000125659701722 12.118932038834952 41.25728155339806 -0.033426136567579 0.3776020138210581 4.31782609196223 3.0753988435553 1.7699755963815147 0.3570217435028845 1.872067837440252e-15 6.208634884992367e-15 3.7666589848112107e-19 2.2033049881987854e-16 6.268436777610976e-11 +Intrinsic component of plasma membrane 62 120 3.7396579434398247 0.0001842708353225 29.711165048543688 79.49271844660194 0.9914207279546418 0.2992612012372248 13.467745416506318 12.62980929789956 2.1277799030157807 0.3627370007757806 1.4926441583401598e-19 0.1948077385941288 3.59016865735144e-05 4.4027038072535976e-18 5.121091310295827e-15 +Late endosome 31 81 3.652283035641565 0.000259919175926 15.655339805825244 65.18203883495146 0.1482522199608934 0.3683478922291265 6.675389202214119 9.543379127098556 1.7080817701484334 0.368772234437858 2.4673851577893605e-10 6.057334666704489e-06 8.361279619655993e-09 2.1204073389972572e-08 5.046232034466e-11 +Endocytic vesicle 40 100 3.6490508916465902 0.0002632109621578 19.521844660194176 83.27669902912622 0.428513908443532 0.5353120905813061 7.647069906220736 7.607555057832984 1.324058617895936 0.3761698531660883 3.899313390079731e-11 0.0174923714516836 6.779613189106715e-08 6.606413934874046e-10 4.42069978134213e-13 +External side of plasma membrane 18 33 3.6280747552713377 0.0002855425911236 6.856796116504855 22.03640776699029 0.7617836494895279 0.3205100812766187 3.0547396608098576 3.343757364022431 1.3549821177336052 0.303342613906597 5.301931538243688e-06 0.0150293110048508 7.591474537533828e-06 4.749794342599983e-05 1.3828438050397356e-07 +Side of membrane 32 87 3.578148631271324 0.0003460366641341 17.526699029126213 71.19660194174757 0.4235531336200628 0.5236659753791312 6.9409272887607125 8.635706418493163 1.198097658489356 0.36822581052137 0.0001432228535188 0.0332787643733133 2.5382317150385407e-05 0.0003456814281795 1.2291887634355078e-07 +External encapsulating structure 18 47 3.5735698497155526 0.0003521472490262 8.740291262135923 33.067961165048544 0.2475250746714072 0.5329464629763961 4.007036034183376 4.3711590871852435 1.0928778643562622 0.3321243069645864 1.3295383825841155e-05 0.0001648060034143 0.0002139788138078 3.0700744680938387e-06 0.0001908123500498 +Endoplasmic reticulum lumen 29 74 3.5633582689384293 0.0003661404208381 18.07766990291262 59.737864077669904 0.9896277047863468 0.3946249358858228 7.513340007333169 6.273245958458151 1.4320597420402308 0.3846324865730224 0.0001954879991768 0.0092751908978721 0.0056874611143685 5.757957730692109e-05 6.541509913663304e-05 +Endocytic vesicle membrane 20 52 3.5503117730952245 0.0003847751770715 11.41019417475728 40.75728155339806 0.6528171904926832 0.3529092384633215 4.825015011915381 4.780047567333447 1.5638167276319088 0.3380752375601685 1.173382938888542e-09 0.1058856107488554 9.458270089211073e-09 1.1158269752884166e-08 6.249973078399626e-10 +Apical part of cell 32 78 3.45264016509163 0.0005551289849774 15.599514563106796 57.72330097087379 0.5629683512109013 0.5412025823450395 6.485031290002554 7.326381428218615 1.086566128273008 0.3654459232984969 2.5841784122052382e-05 0.0027380535511036 0.0029201377895696 0.0003090205302863 3.020332975832392e-05 +Recycling endosome 19 50 3.4480169037918245 0.0005647186936048 11.66504854368932 38.48300970873787 0.3314123370484901 0.5655153978404952 4.733627044629046 5.712973030267684 1.060328776827888 0.3489425897551162 3.718999957483052e-05 0.0339635306200824 0.0026854223739244 0.000196750889837 2.1454176130281165e-05 +Collagen containing extracellular matrix 15 41 3.4139774032585013 0.0006402188541585 7.388349514563107 28.936893203883496 0.1094979606259816 0.5901779878192949 3.847790968094583 3.6231320005554526 0.9701213079318116 0.3238613597958452 2.507037349136972e-05 0.0005859846268907 0.0022520035432667 6.821036261034731e-06 0.0004199119105533 +Membrane microdomain 25 78 3.3105557683906426 0.0009311089629151 14.75485436893204 63.49029126213592 0.5762129399877682 0.5023556315347317 6.545256989336744 6.436953608643344 1.167657055169838 0.3823949317010994 5.07903462218297e-06 0.0148017620517202 0.1165444039160723 0.0008371766481312 6.635161152971628e-07 +Early endosome membrane 22 62 3.291213114129943 0.0009975630879865 12.29611650485437 44.95873786407767 0.5277524243262064 0.5849546522697281 4.982462882428341 7.094079738701261 0.90392558948614 0.3412735259006035 1.1876133746973371e-06 0.1234363306283571 0.006774840164175 8.704466882901423e-06 2.222577067327621e-08 +Azurophil granule membrane 11 25 3.281739558354453 0.0010316884730321 7.856796116504855 21.259708737864077 1.0757479237162697 0.2373572682944545 3.393508570011604 2.63895903142419 1.639408148995933 0.2881313440808664 2.6962379570201922e-08 7.175289272542906e-05 4.639923651669692e-06 8.165847018318476e-09 1.6198865737319365e-07 +Transport vesicle 28 107 3.191652791958876 0.0014146126923764 26.046116504854368 92.34708737864078 0.9512017428916244 0.4458616213657612 9.46815354334768 9.09007867686459 1.424803887648301 0.3967491654773343 1.5318114772798964e-07 0.0385478696321071 0.0001964814237076 3.184550492179178e-07 1.1266402890704133e-06 +Early endosome 43 127 3.178854488008048 0.0014785829740631 24.66504854368932 96.93203883495146 0.530758374709677 0.5743319290889299 8.086272783051246 14.025470683081796 1.1449007118883376 0.3721207721610414 2.332145553872629e-11 0.0119845399878974 7.892719355135551e-05 8.271983065405536e-10 3.678643922276898e-12 +Pigment granule 17 64 3.158876141025051 0.001583787848385 17.058252427184467 60.37135922330097 0.3452760243889364 0.5728855837677844 7.454164461546019 2.3255555964379067 1.200064167427868 0.3798846852248331 1.168314537235293e-07 0.0718661948949039 0.0017072304004418 5.854128614215956e-05 4.3271487840397705e-08 +Phagocytic vesicle 20 47 3.128145154457642 0.001759132812855 11.54126213592233 41.59708737864078 0.3919256884663005 0.5681630099638236 4.854259100699266 4.0100348958770144 0.9938295058309184 0.3509625084864278 7.838205326676336e-05 0.086158736226278 0.0027125023591425 0.0001434833065057 5.382001706156264e-06 +Apical plasma membrane 26 62 3.0477292775497187 0.0023057755239608 13.313106796116504 44.91504854368932 0.8056122914935105 0.4638533528605782 6.08368206230376 5.803837594461636 1.1490032654706197 0.3657186109722784 9.548829296124164e-05 0.0421277892223037 0.0656047650092995 0.0015307386537109 7.483366058766559e-05 +Autophagosome 13 39 3.0458194398379024 0.0023204713933382 7.490291262135922 28.23058252427185 0.2382857558920592 0.551676712271876 3.4770262532301657 5.388565442188036 0.9533210099421008 0.3228297396792804 0.0036335926609047 0.0760657989123155 0.001973739432479 0.0071204993039649 0.0001424733812482 +Basolateral plasma membrane 27 53 3.020644743184535 0.0025223711636781 11.907766990291265 41.713592233009706 0.4173504135492652 0.5464661760255546 5.696723454799589 5.533263026209871 1.098008793343998 0.3512755123780914 6.280250851536739e-05 1.0 0.303304644259416 0.0211649125155811 4.920592800157797e-09 +Basal part of cell 23 62 3.009484180756325 0.0026169170619823 12.87378640776699 49.39563106796116 0.4231791430151931 0.5418083225496748 6.317535484281435 5.887808725837185 1.1575518486276402 0.3620095959132046 0.0001053197521425 1.0 0.3906542776432947 0.0200202272568271 1.2086601835448253e-08 +Recycling endosome membrane 12 31 2.9925893509240664 0.0027662168008117 6.888349514563107 22.509708737864077 0.1536767921278238 0.6101735952601732 3.1901182670006487 3.1100218387491214 0.9055004805495972 0.3161343906862945 0.0001622020398219 1.0 0.034172513126223 0.0003907769995998 4.796010676958018e-05 +Exocytic vesicle 10 43 2.984028798623421 0.0028447999497247 12.106796116504857 38.40533980582524 0.7408080162244459 0.4227017753873355 4.952517495270036 4.6543925000719675 1.3317240485888555 0.365166844745196 0.003812345445725 0.0288500723595301 0.009900871746126 0.0171137548039357 0.0321762433468636 +Vacuolar membrane 64 146 2.9025393385290097 0.0037015066822472 31.91504854368932 121.20631067961163 0.8693310080509177 0.3422944242486927 10.598363436017626 13.850227259030053 1.9844114292962869 0.3837860427998523 6.264080335841212e-22 5.142249452092758e-07 6.063404842609022e-13 3.9721936872183376e-18 1.3683149469108592e-22 +Coated vesicle membrane 15 64 2.8659559764171103 0.0041575205729917 12.470873786407768 56.310679611650485 0.4487003631021872 0.5093312281655428 5.273732877175169 4.573093801439982 1.1487677393522833 0.3682374685669872 3.4217270152610543e-06 1.0 0.00013490464849 5.01787287549476e-06 0.0001731590940626 +Snare complex 14 21 2.833550962757067 0.0046033967115544 6.20873786407767 15.79368932038835 0.8138466711937282 0.3737991711938105 3.1112263618988054 3.010283181947674 1.1802712183474584 0.3261149602927671 0.0058182884516871 1.0 1.0 0.0195417527514502 6.656073684714697e-08 +Clathrin coated endocytic vesicle membrane 8 17 2.8174398780998877 0.0048408176766663 3.796116504854369 13.682038834951456 0.0573666642471241 0.400612365903674 2.3816010903207343 1.646817383208435 1.3652035545006669 0.3297171871883064 3.248353470471016e-06 1.0 8.755679254602859e-07 1.6496543161655165e-05 3.120228094674925e-05 +Golgi associated vesicle 10 36 2.804034476786399 0.0050467508182643 6.745145631067961 30.33009708737864 0.696501539533066 0.3869218626415568 3.3093865809086713 3.3403631844705557 1.2881306559419168 0.3350067162782171 8.331987767950208e-05 0.0437266531990119 0.0040840095186766 3.408063785478731e-05 0.0003852385445581 +Clathrin coated endocytic vesicle 8 23 2.758117460717082 0.0058135304085431 4.774271844660194 18.74271844660194 -0.0983362729934113 0.4816370533307881 3.136849294900222 2.1033538609603957 1.2416005860349415 0.3436375292109884 2.3522929158622367e-05 1.0 4.066081157623494e-06 9.063996119237736e-05 4.480952963287816e-05 +Transport vesicle membrane 12 50 2.754414274446931 0.005879729089169 12.62135922330097 42.37378640776699 0.5402420874587609 0.5343084089707166 5.404271063272784 4.511161156897919 1.052801184280702 0.3556606283757049 0.0007373509349062 0.4717478376334574 0.03553181045856 0.0011084219389813 0.0096128498471313 +Endosome lumen 5 8 2.735405130230629 0.0062303542756982 1.604368932038835 3.8932038834951457 0.8845546079995737 0.2641736972645504 1.2526788149416888 1.4642180149570363 1.3478975321629194 0.2569719391794136 1.0491355633185285e-05 3.3882224489623025e-08 2.3487466603751172e-08 5.415752101895563e-06 0.0002717294391002 +Coated vesicle 23 100 2.721234604395445 0.0065038585778158 21.15776699029126 89.28398058252426 0.7996411773181966 0.4463095457932411 7.252509633536616 8.542551157088123 1.3406722753228342 0.3892656029628454 1.10137333792075e-07 0.258876638823261 2.197434324659721e-05 7.595520951156258e-08 4.313520949750249e-06 +Phagocytic vesicle membrane 11 28 2.697518736787787 0.0069858353318346 7.512135922330097 23.83009708737864 0.5348434256443761 0.4468744105904624 3.681144332021715 3.0024693704800938 1.1652764437248655 0.3385441964418395 0.001233886009584 0.2597451867723493 0.0027541417385927 0.0033989983353886 2.905428449216434e-05 +Clathrin coated pit 6 33 2.695382974579524 0.0070307769870974 6.813106796116505 23.92233009708738 -0.3634603746412232 0.5290548253531329 3.4198908541960824 3.6938398480544263 1.0001526474813611 0.326415656204558 0.0008196932585148 0.0316917589218704 0.0002087091356766 0.0004129808075874 0.0195107872901531 +Tertiary granule 18 44 2.689582715824343 0.0071541414738567 10.41504854368932 41.036407766990294 -0.0889487004392956 0.5196752089107607 4.251221040765739 3.0949590565759384 1.1107953602779526 0.3305399634314611 6.423490411162016e-06 0.0102615341834231 0.0002475664110718 7.074199918744216e-05 3.201222242580179e-05 +Trans golgi network 21 80 2.663417998878212 0.0077351262015226 15.419902912621358 63.34466019417476 0.3899535194812628 0.596168565313415 5.947659406670704 9.796108085479462 0.9254595120691144 0.3511819564605877 0.0009232295524444 0.2515758385923512 0.0410933730804736 0.0029348562292467 0.0002163573331248 +Clathrin coated vesicle 13 55 2.629920438233923 0.0085404853182275 9.936893203883496 47.157766990291265 0.2628715125167937 0.534532305855711 4.553447222704333 4.879804116719352 1.1779559306555245 0.358217133589648 0.0001117542646389 1.0 0.0001661307432349 0.000170845725604 0.0002561121352377 +Clathrin coated vesicle membrane 8 29 2.614087557208742 0.0089466105892239 5.987864077669903 23.8373786407767 -0.1745074444216576 0.5217181929114124 3.796056755917445 2.6366094957976225 1.1352900407304896 0.3325344982200064 0.0002209896429827 1.0 2.4490692503129386e-05 0.0006279861154086 0.0025023010526467 +Autophagosome membrane 9 18 2.58701826244676 0.0096810461007716 4.174757281553398 13.37135922330097 -0.0098942360451326 0.445924723627937 2.326200220393679 3.0901432865083773 1.1383635180898088 0.3067757682348186 0.0064222178805025 0.1948770046367652 0.0085749794431607 0.0211003003498726 3.640676118594351e-05 +Endolysosome 3 12 2.5355626716010757 0.0112266838056318 3.3810679611650487 8.798543689320388 -0.4980552085105273 0.4508748211144175 2.1526526479127432 1.5874806980048122 1.0027139446036482 0.3093335090902263 0.0014768241824232 0.0001017478453213 2.7844996115802127e-05 0.000963248429344 0.0118045746321095 +Golgi cisterna 16 33 2.526426914391122 0.0115229361133437 8.524271844660195 22.490291262135923 0.9086972174309816 0.318868202549777 4.2525712614684625 5.269200019661922 1.391079392561209 0.3149122340418913 3.759321161123021e-06 0.3024216363859021 0.0006633301665035 1.2254814710404596e-06 1.662070048299966e-06 +Neuromuscular junction 9 21 2.499073206356071 0.0124518585506316 4.62621359223301 16.633495145631066 0.4855035135155566 0.54061233402628 2.386469186408936 2.9236472131013795 0.8090611388618595 0.3124321260069755 0.0058182884516871 0.1908924307699622 0.0640285846884502 0.0195417527514502 0.0042432632735376 +Golgi lumen 3 7 2.49875278235578 0.0124631220878412 1.745679012345679 4.548148148148148 1.1368717941323 0.2457507117503182 1.2159484823715767 1.4039724163790972 1.161880305109492 0.2643265801751675 0.0104036547903649 0.1457663642848915 0.266209970857853 0.0069928111010265 0.0670368145723744 +Multivesicular body 7 13 2.4459755896464537 0.0144460780828681 3.7742718446601944 12.094660194174756 0.0270444117783637 0.5442226252774409 2.4800207883335372 2.61498122866677 0.9464580912617488 0.3033802150556732 0.004732381298193 0.1828652209005429 0.0070463522145746 0.0166437437365411 0.0032176405980257 +Blood microparticle 5 19 2.420927354927307 0.0154809706529686 4.735436893203883 17.08252427184466 0.278306270999014 0.48728609275096 2.8336409309630577 1.4740425350178823 1.0421411126986748 0.31816279579515 0.005255517230189 0.1868885334554594 0.0614247268920475 0.0032221742646108 0.0149334923888548 +Sarcolemma 10 30 2.42001371368823 0.0155199217909982 6.849514563106796 24.82766990291262 0.1401032497752024 0.6240915375619693 3.1177030936067345 2.404871957871013 0.82647351967221 0.3084890241561867 0.0025404076176974 1.0 0.4876012483283494 0.0849374332498421 0.0004387106656971 +Late endosome membrane 17 45 2.399603496566617 0.0164128393175224 8.400485436893204 35.220873786407765 -0.1907871949509251 0.3412955054288843 4.360825137615114 6.285848739997517 1.5677242851178623 0.3272837423268039 5.090478375683994e-06 0.0029387205772029 2.1371467570449795e-05 7.272818537753751e-06 5.82322742774119e-06 +Intrinsic component of golgi membrane 7 12 2.39103142242128 0.0168011148770521 4.655339805825243 10.08495145631068 1.3178763872097854 0.2129685736028588 2.6046347098798024 1.9780511021437377 1.2704958978874823 0.2699640456705705 0.0262642634944141 1.0 0.3339976348230559 0.0801176308941427 0.0149334923888548 +Presynapse 35 108 2.384365068094997 0.0171086207877235 22.813106796116504 90.997572815534 0.4365135448276876 0.6534842370695999 7.919284748658944 8.50627945845188 0.826940228235506 0.3445781590237917 0.0100593711302667 0.1610739044788785 0.1364138903956117 0.1469400144007308 0.0001077876997047 +Autolysosome 4 5 2.370665956054806 0.017756070623691 1.2742718446601942 2.5 0.0538016229797333 0.3242545358762464 0.8302638508467117 0.8936127177476764 1.6121582479288443 0.2995280680557608 3.160792089650874e-06 0.0010343090391069 1.612359251599596e-06 1.7923085924657402e-06 5.383729574080712e-05 +Secondary lysosome 4 5 2.370665956054806 0.017756070623691 1.2742718446601942 2.5 0.0538016229797333 0.3242545358762464 0.8302638508467117 0.8936127177476764 1.6121582479288443 0.2995280680557608 3.160792089650874e-06 0.0010343090391069 1.612359251599596e-06 1.7923085924657402e-06 5.383729574080712e-05 +Trans golgi network transport vesicle 4 15 2.334404469328966 0.019574552989851 4.007281553398058 12.91019417475728 -0.165056273529708 0.5953281491980702 2.4210736181324606 1.5961704659812874 0.9219447964283688 0.3231276900084591 0.0390334633726749 1.0 0.0293903981750984 0.0291459656321865 0.0101939997718642 +Chloride channel complex 4 7 2.3200257757373968 0.0203394830097081 1.6310679611650485 5.075242718446602 0.2943428743278045 0.4119582773335843 1.172005925149341 1.1561018739840807 1.1032422410077494 0.2897431462530468 0.0002190470461162 0.0573151884822011 0.0001778916397324 0.0001405335592956 0.0001560226497295 +Ficolin 1 rich granule membrane 6 18 2.315979073846093 0.0205594112892439 4.395631067961165 17.803398058252426 0.1552184768165 0.4321380562295095 2.362999644561935 1.270535437467333 1.1498286388022771 0.2935073244440836 0.0002229574617941 0.0112943240362007 0.0002651548018521 0.0010720436073174 0.0008544422426654 +Specific granule membrane 9 19 2.2970845034053187 0.0216139496136915 4.703883495145631 15.434466019417476 0.8701513897757543 0.3699585460258285 2.477017558764293 2.6655071934549124 0.9998631482292508 0.308737972868479 0.0429933331736 1.0 1.0 0.1140816659952819 0.0088173905438192 +Golgi stack 17 44 2.2614703516148955 0.0237301466199033 9.67233009708738 31.25242718446602 0.7055900861920908 0.4265468940333196 4.557817503574521 5.847941213698429 1.2226912303929196 0.3463938041520717 6.504534941743566e-05 0.3837329617083285 0.0024838215389039 2.268431432943328e-05 6.830567610643416e-05 +Endosome membrane 53 157 2.258654695426327 0.0239048726695727 28.436893203883496 125.75485436893204 0.1968108610887141 0.5657595498250074 10.058247741499075 16.477863960688197 1.2734596099850304 0.3756178998455078 1.0679647777538162e-11 0.0104995508747154 1.1223514560047565e-07 1.4589167457239683e-10 6.871462556375455e-13 +Presynaptic active zone 5 17 2.2578341066186467 0.0239560039788568 4.803398058252427 14.970873786407768 0.3940654670567658 0.5114928405011878 2.7795522630987173 1.9568466345271975 0.9528581059832693 0.3105803383532612 0.0429933331736 0.2145132052110039 0.0803922289273931 0.3318756245718339 0.0300212330028383 +Golgi membrane 56 167 2.255393673022027 0.0241086295302335 41.28398058252427 131.19174757281553 1.6327747521284677 0.3511039607499193 15.277988344159814 17.44963987873233 1.926180921267262 0.4033858283713009 6.063890009040754e-11 0.0561151176528592 1.1874669860853984e-05 5.851282203470561e-10 1.4084883209773769e-12 +Caveola 5 17 2.24925064288104 0.024496554097952 2.9466019417475726 14.70873786407767 0.8985606687711867 0.3693669899268542 1.8868639175868975 1.4590265937218798 0.8676345315740439 0.2906359774944637 0.1659533218790633 1.0 1.0 0.7200709140128994 0.0387569851109487 +Tertiary granule membrane 7 13 2.237274401716086 0.0252684112031322 3.5825242718446604 10.990291262135925 -0.12394176795591 0.5540533251246273 2.018238546836114 1.663398939422297 0.903690683619067 0.3035012110658648 0.0680331793156344 0.1583124314184509 0.2872333566147377 0.051542815486873 0.0061413176576109 +Vesicle lumen 26 136 2.232103750742009 0.0256081066039191 28.93446601941747 119.79368932038837 -0.0708316930912348 0.5682496130595786 13.122391611595372 7.240907185867801 1.2978103845669404 0.3622974798457447 2.7793172047359758e-11 8.616712578016403e-12 3.759291312350702e-14 8.230567896149523e-11 3.191825524353972e-08 +Platelet alpha granule 6 22 2.2284437923407627 0.0258509355762548 4.211165048543689 15.902912621359222 0.6039612674990132 0.4510107266729922 2.510477385063311 2.1030009215071965 0.8798256715017497 0.2887985186703408 0.005255517230189 0.1868885334554594 0.0614247268920475 0.0032221742646108 0.0007880746078161 +Golgi apparatus subcompartment 34 116 2.2233753467586146 0.0261905006597982 23.898058252427184 88.56796116504854 0.6438651907142603 0.5157075238910589 9.044082768463602 13.85685287398648 1.2182273227220288 0.3801323692583779 3.53506734308963e-07 0.1493637558109807 0.0012172861714086 6.891647425156586e-07 1.1651999422049249e-07 +Endoplasmic reticulum golgi intermediate compartment membrane 11 29 2.21645971200481 0.0266600341322449 10.49271844660194 25.839805825242717 1.5441023898993702 0.2324243418613106 5.505729177420246 3.7718384126099376 1.49831312620529 0.2965572765953523 0.0006587569464332 0.237457799625543 0.4129317333780675 0.0003302169514715 0.0002657806893448 +Phagophore assembly site 7 13 2.214016016609725 0.0268276771627899 2.628640776699029 7.565533980582524 0.2063328848611747 0.5409718819014401 1.824976418809582 2.232390954796877 0.8729628008322181 0.2961936151390784 0.0505053913877401 0.141543756104335 0.2590666885683055 0.1713585638073601 0.0032807303767948 +Integral component of synaptic vesicle membrane 2 5 2.1877708071897515 0.0286863013543334 2.2475728155339807 4.910194174757281 0.8567274645780141 0.3149754325120096 1.3818760752746044 1.4445051429216968 1.1133243513780926 0.2989777184888048 0.0100699756610546 1.0 0.1515272625734178 0.0073447144383531 0.046330877355434 +Plasma membrane raft 10 26 2.166849506144346 0.0302463311721572 3.7766990291262137 20.32281553398058 0.7112808016258366 0.472560537547523 2.42331730763724 2.337985988096463 0.7987766314420426 0.3131348956705554 0.034691382732658 1.0 1.0 0.2193268794643932 0.0151785573456272 +Vacuole 92 261 2.149410994429753 0.0316018346816893 55.029126213592235 212.35679611650485 0.7895788564169173 0.4204713883128338 16.092847298969616 21.031446114270427 2.221429361906059 0.4148180554719883 2.1567280455224117e-43 9.688394661356754e-35 2.1723478411469297e-42 5.330492450152464e-41 6.612773730155419e-39 +Lumenal side of membrane 3 9 2.137581033967888 0.0325507624108631 3.686893203883495 9.509708737864075 0.6270696996832885 0.3351332813726532 1.8490414883089543 0.9791034697552432 1.2332692274886168 0.3003490996154719 0.0026147713450664 1.0 0.018640880521655 0.0017174581383874 0.0198699646710478 +Platelet alpha granule membrane 2 5 2.130912583921909 0.033096344483789 0.8025316455696202 2.081012658227848 0.2614281433644114 0.3504902455917955 0.7607415908085344 1.052312215951031 1.6089664801163488 0.3217900283945228 0.0036004577965194 1.0 0.1094892401774078 0.0025975272437437 0.0179235086559622 +Golgi cisterna membrane 7 24 2.12046376833341 0.0339669539066211 6.233009708737864 17.101941747572816 0.7930989258143627 0.3092897028410761 3.2184356191878685 3.952300069740005 1.3504727992091758 0.2953094162507478 6.969921531422637e-05 1.0 0.0890100643743446 3.079730523933523e-05 0.0001637882770494 +Intrinsic component of postsynaptic density membrane 1 5 2.1176918294153584 0.034201175285272 1.0025188916876575 2.584382871536524 0.2019423245773231 0.5305626058493798 0.8765019223710706 0.965948162899742 1.120765393422286 0.3378360254203664 0.084064100232846 1.0 0.1596960736798767 0.0688460117016781 0.2160114460330814 +Specific granule 14 42 2.114524201975704 0.0344705199064383 8.742718446601941 34.25242718446602 0.2855678993885875 0.5987101990719559 3.996578681039245 4.349352025395783 0.8117156191720855 0.3097397590453908 0.0027640675504883 0.3555919235953944 0.0540767090111314 0.0056146507740375 0.0036803591594937 +Nuclear envelope lumen 2 6 2.105658599189989 0.0352340185186079 1.5922330097087378 4.730582524271845 0.2740214243637495 0.4274662744917171 1.0138544466097483 0.5098416377826835 1.1584731829510644 0.3162624936844113 0.0003693662950738 0.0290719737908623 1.6865595784317113e-05 0.0002629541815867 0.0020257428393968 +Cis golgi network 7 20 2.09167388534472 0.0364676981274378 5.446601941747573 14.91747572815534 1.304763677188147 0.2415633778835601 2.9087352716231463 3.2280604409731746 1.23405443481851 0.2890539664507128 0.087927706130726 1.0 1.0 0.0671599559498881 0.000466746230466 +Gtpase complex 5 6 2.0741771769645085 0.0380628590425813 2.825242718446602 5.762135922330097 -0.1808659599804917 0.5236564698046904 1.7731940599092544 1.6827864377624848 0.9640096100125498 0.3140885032192029 1.0 1.0 1.0 1.0 0.0267540631687978 +Synaptic vesicle membrane 8 16 2.0632026988723915 0.0390933738377801 5.099514563106796 14.07766990291262 0.7734258277348643 0.4227625879426745 2.579286376297321 2.2325453295101236 1.0485572818049853 0.3297289695807819 0.082762113518218 1.0 0.4461675288226883 0.1820516573570916 0.3424310058709896 +Copii coated er to golgi transport vesicle 6 34 2.060768261304192 0.0393251537856462 10.810679611650484 32.4247572815534 0.9209697551014924 0.3949407296339237 5.01338814607213 3.9617918728777735 1.2509556054930144 0.3456813773327062 0.0093433883221268 0.0425713267043903 0.0264876267470493 0.0054207505619159 0.0151785573456272 +Receptor complex 16 33 2.0589801672612253 0.0394961384279111 4.546116504854369 19.37135922330097 -1.0257716368983243 0.3014359024485322 2.884560417457156 4.82966712727482 1.2452382063769163 0.3057220790362489 0.0005964209612106 0.1603872358408925 0.0131695212123147 0.0008022847163198 0.0002370762273245 +Neuron spine 13 34 2.022129553103766 0.0431629696460884 7.320388349514563 32.932038834951456 0.1209242177622 0.6809363437375507 3.7168302400904287 4.412608008353455 0.7061730550262219 0.293096381963579 0.7862046258916346 0.4077336964203657 0.6426690076912178 0.7296565158334214 0.0712576838200765 +Messenger ribonucleoprotein complex 3 6 2.0158766206377923 0.04381287890665 2.1432038834951457 4.978155339805825 0.6946670661171017 0.4479616993324847 1.1952078371419346 0.8401389709046068 0.8841292807137072 0.3125159243383019 0.2400848710653836 1.0 1.0 0.2167775624926856 0.0009048869233579 +Intrinsic component of postsynaptic specialization membrane 1 6 1.9850824157447984 0.047135302841057 1.291358024691358 3.407407407407407 -0.0399397817325968 0.5651656703897867 0.9732467656663693 1.1350507442594342 0.9765497147038276 0.3163577523575487 0.109521701366213 1.0 0.1837383274168749 0.0901924811619011 0.2707381743872572 +Golgi medial cisterna 3 5 1.98467304137534 0.0471808600527232 1.4902912621359223 3.4733009708737863 0.7236971844675457 0.3405036808602053 1.1266424526606664 1.239231588055279 1.2311376953203692 0.3093903079022938 0.0341781603031309 0.0526645480715484 0.0047533286028597 0.0276231155809849 0.0013678067399173 +Ciliary base 4 8 1.9841494971789344 0.0472391766120603 2.283980582524272 6.325242718446602 -0.0471430007205836 0.6414436270613587 1.6603414316115448 1.095464475378326 0.7174998714144822 0.2828696413658497 0.1944778963944218 1.0 1.0 0.5198923492291299 0.4305195758208063 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..df8d1f351a6e1e8039b2b016df887e3e15aeb363 --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 919, + "title": "Average number of proteins per term", + "value": 32.50489662676823 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0ac31a3282486e02ff6146681bab27e704b70947 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..87a686d972c2e2bcb7d4d97b78edec16b73644b9 --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,315 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Vacuolar lumen 0.8592872580643877 5.353434622894973 8.630022486615604e-08 7.930676512737232e-05 7.930990665291641e-05 77 O14773,Q9UMR5,P07711,O75629,P07858,Q9UM22,Q8NHP8,O00584,Q9BTY2,P13473,P04062,P07602,P06280,P15586,P17900,Q9UBX1,P11117,Q99538,Q8IV08,P16278,P34059,P50897,P54802,P53634,P06865,P15289,P61916,Q13510,O00462,P10253,P07686,Q92820,P08236,P38571,P10619,Q14108,P02792,P04066,Q99519,O00754,O00560 41 +Azurophil granule 0.775048877601527 4.7275624840893595 2.272311495854495e-06 0.0020860777463436 0.000860146528807 77 O75629,P42785,O00584,Q9BTY2,P13473,P07602,P06280,P15586,P17900,P16278,P34059,P15289,P53634,P06865,P61916,O00462,P10253,P07686,Q92820,P08236,O15260,P10619,P02792,Q9NQX7,P11279,P04066,O00754,P27105,Q92542,O00560 30 +Lysosomal lumen 0.929758170350766 4.684395213448448 2.807877678367987e-06 0.0025771167275101 0.000860146528807 45 O14773,Q9UMR5,P07711,P07858,Q9UM22,Q8NHP8,O00584,P04062,P13473,P07602,P06280,P15586,P17900,Q9UBX1,P11117,Q99538,Q8IV08,P16278,P34059,P50897,P15289,P54802,P06865,P61916,Q13510,O00462,P10253,P07686,P38571,P08236,P10619,Q14108,P04066,Q99519,O00754 35 +Cell surface 0.7282133463271434 3.957908533113964 7.560889821545125e-05 0.0671279300512939 0.0166823749470822 107 Q99523,P14174,P07858,P01889,O75955,Q14118,P00533,P05067,Q8WTV0,P19021,P17301,P06756,P11233,P55899,Q07021,P51790,Q92673,Q9BQT9,P11717,Q7KYR7,Q13641,P98164,Q9H813,P01130,P13591,P04439,P29317,O75787,Q08722,Q13685,P02786,Q92692,P11279,P41440,P05556,P42892,Q04721,O43847,Q14126,Q92859,P10321,Q08431,Q9UNN8,P08195,Q6YHK3,Q9Y6N7 46 +Secretory granule membrane 0.6886570526945981 3.914042266166319 9.07637374705228e-05 0.0800313267658392 0.0166823749470822 86 Q93050,P42785,P30519,P01889,P13473,P07602,P16870,P19021,P48960,P35613,P06756,O00462,P10253,Q06481,P51809,P11717,O15260,Q9NQX7,O75787,Q08722,Q9NV96,Q9Y6X5,P11279,O60245,P27105,P10321,Q08431,Q92542,Q6YHK3 29 +Azurophil granule lumen 0.7839145700541725 3.8348133107681894 0.000125659701722 0.1090692018615095 0.0192468776470971 47 O00754,P16278,O75629,P34059,P15289,P53634,P10619,P61916,O00584,Q9BTY2,P07686,Q92820,P06280,P15586,P08236,O00560,P17900,P04066 18 +Intrinsic component of plasma membrane 0.7216384018556572 3.7396579434398247 0.0001842708353225 0.1557954890960778 0.0241921282373496 120 Q9P273,P01889,P15260,Q9BTU6,Q96QD8,P00533,P05067,Q8WTV0,P51805,P48960,P17301,Q9UIQ6,Q14517,P35613,P06756,Q99805,P51790,Q92673,Q9BQT9,O60266,P11717,Q7KYR7,P11166,Q13641,Q9H813,P01130,Q9NPF0,P04439,O60637,P29317,Q08722,P02786,P10586,O43657,O14786,P11279,P41440,Q15043,O60245,P05556,Q04721,Q9NR28,P27105,Q92859,P10321,Q96J84,Q92542,Q9H2J7,P20645,Q8NBJ4,P17152,O00592,Q15375,Q9UNN8,Q9UNK0,O00560,P30825,P78310,O75882,Q07954,O15118,Q9Y6N7 62 +Late endosome 0.6491058314110358 3.652283035641565 0.000259919175926 0.2125038293391662 0.0252577419806275 81 Q9BXS4,P07711,Q7Z3C6,Q13501,Q8IY95,P13473,P00533,O15400,P07602,Q9UEU0,Q9ULH0,Q99538,Q8IV08,Q9BXW6,P51790,Q9H7F0,O95772,P10644,Q92673,P51809,P11717,Q14108,Q9NQ11,P01130,Q9NUM4,Q9NV96,P11279,Q15043,P20645,Q9UNK0,O15118 31 +Endocytic vesicle 0.6799828219999242 3.6490508916465902 0.0002632109621578 0.2148831462322199 0.0252577419806275 100 Q93050,P07711,P01889,O00461,Q16625,Q5KU26,P13473,P00533,O15400,Q9Y487,Q8WTV0,Q9H223,Q9NQZ7,Q9H4M9,P06756,P11233,P51790,Q06481,P51809,P11717,Q14108,P98164,P01130,P04439,O14641,Q86Y82,Q04656,P02786,P11279,O43493,Q14254,O43752,P10321,P20645,P51151,O00161,Q9UNK0,Q07954,O14964,P08670 40 +External side of plasma membrane 0.8017323931160201 3.6280747552713377 0.0002855425911236 0.2308360348252995 0.0252577419806275 33 P17301,P01130,P06756,P13591,P05556,P42892,P07858,P55899,Q08431,P51790,O75787,O75955,Q14118,P02786,Q7KYR7,P11279,P41440,P98164 18 +Side of membrane 0.6505260807464148 3.5781486312713233 0.0003460366641341 0.2724428513644891 0.0252577419806275 87 P07858,P01889,O75955,Q14118,P63096,P07947,P17900,P17301,P06756,P55899,P51790,P04899,Q7KYR7,P10619,Q5ZPR3,P98164,P01130,P13591,P04439,P08754,P09471,O75787,P02786,Q9Y4F1,P11279,P05556,P42892,Q9NR28,P10321,Q08431,P43121,P41440 32 +External encapsulating structure 0.7442969103992201 3.5735698497155526 0.0003521472490262 0.2765185096834327 0.0252577419806275 47 P07711,Q92896,O43405,P13591,P07858,Q32P28,P53634,Q08431,P14543,Q5SZK8,Q5KU26,Q14118,O94898,P07602,Q08380,O75882,Q6AZY7,Q9UBX1 18 +Endoplasmic reticulum lumen 0.6267784462448298 3.5633582689384293 0.0003661404208381 0.2857660161206332 0.0252577419806275 74 O95881,Q13217,Q13438,Q07065,P19022,O00584,Q9BTY2,Q9NWW5,Q14118,Q9P2K2,P05067,Q02818,Q14257,O75718,P15289,Q32P28,P53634,O15460,Q9NWM8,Q06481,Q9Y680,Q15293,P07942,O43493,O43681,Q08431,Q8NBJ4,Q8IXB1,O43852 29 +Endocytic vesicle membrane 0.7245988252108512 3.5503117730952245 0.0003847751770715 0.2978978937605164 0.0252577419806275 52 Q93050,P01889,Q5KU26,P13473,P00533,Q9Y487,Q8WTV0,Q06481,P51809,P11717,Q14108,P98164,P01130,P04439,P02786,P11279,O43493,P10321,P20645,Q07954 20 +Apical part of cell 0.6209350282398164 3.45264016509163 0.0005551289849774 0.3996876602146938 0.0324360299639291 78 P07711,P07858,P19022,Q16625,O75955,P55011,P05067,O43865,Q99538,Q14517,P33527,P51790,P11166,Q13325,P98164,P01130,O14641,O75787,Q04656,Q9NV96,Q14254,Q15043,Q99808,P41208,O00592,Q12959,P08195,P30825,P41440,Q9NP72,P05026,Q9Y6M7 32 +Recycling endosome 0.716579286881562 3.4480169037918245 0.0005647186936048 0.404957871936225 0.0324360299639291 50 O14773,Q7Z3C6,P01889,O15400,Q9H223,P05067,Q9UEU0,Q9Y2I1,Q9H4M9,Q9H7F0,P51790,Q92673,P04439,Q86Y82,P02786,P05556,P10321,Q9UNK0,Q92581 19 +Collagen containing extracellular matrix 0.7360721896498568 3.4139774032585013 0.0006402188541585 0.4448681063980602 0.0346094780571591 41 P07711,P13591,O43405,P07858,Q32P28,P53634,Q08431,P14543,Q5SZK8,Q14118,P07602,Q08380,O75882,Q6AZY7,Q9UBX1 15 +Membrane microdomain 0.6048308352533184 3.3105557683906426 0.0009311089629151 0.5751791610241639 0.047406085335827 78 O14773,Q9BTU6,P13473,Q14118,O75955,P00533,Q8WTV0,P05067,P35613,P50897,P10644,P04899,P11166,Q86Y82,Q04656,Q14254,P05556,P21796,P27105,O00592,O00560,P78310,P41440,P05026,O15118 25 +Early endosome membrane 0.6516043960388945 3.291213114129943 0.0009975630879865 0.6003707534787204 0.047406085335827 62 P01889,P00533,Q8N4V1,O15400,Q9H223,Q9UEU0,Q9H4M9,Q8IV08,Q9NYA4,Q9H7F0,P51790,Q96J02,Q92673,Q06481,P04439,Q86Y82,Q04656,Q9NV96,Q15043,P10321,Q92783,Q92581 22 +Azurophil granule membrane 0.8050003293427033 3.281739558354453 0.0010316884730321 0.6127214690013282 0.047406085335827 25 P42785,P27105,Q9NQX7,Q92542,O00462,P10253,P13473,P07602,Q9NV96,P11279,O15260 11 +Transport vesicle 0.6380051259064538 3.191652791958876 0.0014146126923764 0.7277268398042449 0.0617644433256364 107 Q99523,P01889,O00461,O15400,P16870,P05067,P19021,Q9UEU0,P50897,P51790,O95249,Q92673,P24390,P51809,P11717,O15260,Q9NQ11,P04439,Q86Y82,Q9NV96,P11279,O43493,Q7L0J3,O43752,P10321,Q92542,P20645,O43760 28 +Early endosome 0.6661186189969656 3.178854488008048 0.0014785829740631 0.7432938688462063 0.0617644433256364 127 Q99523,P01889,Q9Y6W5,Q9NWW5,O75955,P00533,O15400,Q8N4V1,P05067,Q9H223,Q5VW38,Q9UEU0,Q9Y2I1,Q9UIQ6,Q8IV08,Q9H4M9,Q9NYA4,P51790,Q13510,Q9H7F0,Q96J02,Q92673,Q06481,P11717,P01130,P04439,Q86Y82,Q04656,P02786,Q9NV96,O14786,Q15043,O43752,P10321,Q92542,O60291,P31751,Q9UNK0,Q92783,Q92544,P41440,Q07954,Q92581 43 +Pigment granule 0.6268399016442578 3.158876141025051 0.001583787848385 0.7669855601013725 0.0632826535941694 64 Q93050,O14773,P35613,P27105,P07858,Q92542,P55209,Q04656,O75955,P02786,Q92820,O00560,P08195,P11166,P11279,P41440,O43852 17 +Phagocytic vesicle 0.6794626453028364 3.128145154457642 0.001759132812855 0.8017183272836138 0.0673601272922395 47 Q93050,P01889,P13473,Q9Y487,P06756,P33176,P51790,Q06481,P51809,P04439,Q86Y82,Q04656,P11279,O43752,P10321,P51151,O00161,Q9UNK0,O14964,P08670 20 +Apical plasma membrane 0.6210707681810836 3.0477292775497187 0.0023057755239608 0.8801428241598831 0.0820197388645325 62 P07711,P07858,P19022,Q16625,O75955,P55011,O43865,Q14517,P33527,P51790,P11166,P98164,O75787,Q04656,Q9NV96,Q14254,Q15043,Q99808,O00592,Q12959,P08195,P30825,P41440,Q9NP72,P05026,Q9Y6M7 26 +Autophagosome 0.6845275498248942 3.0458194398379024 0.0023204713933382 0.8817543764768389 0.0820197388645325 39 P02792,Q7Z3C6,Q13501,O75787,Q9Y6I9,P13473,Q8TDY2,Q9Y3E7,Q13137,Q13772,Q6PHR2,P11279,Q9NQ11 13 +Basolateral plasma membrane 0.6481143216918828 3.020644743184535 0.0025223711636781 0.90182341436681 0.0858540407192674 53 Q9Y6W5,O75955,Q14118,P00533,P55011,P35613,P33527,Q14168,P11166,P01130,Q9BY67,P22413,Q04656,P02786,O14936,Q6P4Q7,Q14254,Q15043,Q99808,Q12959,P08195,P30825,P41440,P78310,Q07954,P05026,Q9Y6M7 27 +Basal part of cell 0.6163511572082029 3.009484180756325 0.0026169170619823 0.9100138090026108 0.0858909564272049 62 P42785,O75955,Q14118,P00533,P17301,P35613,Q14168,P11166,P01130,Q9BY67,Q04656,P02786,O14936,Q6P4Q7,Q14254,Q15043,P08195,P30825,P41440,P78310,Q07954,P05026,Q9Y6M7 23 +Recycling endosome membrane 0.7134201777212588 2.9925893509240664 0.0027662168008117 0.9215799630609844 0.0871457051265682 31 Q9H4M9,P04439,Q7Z3C6,P01889,Q86Y82,P10321,Q9H7F0,P02786,Q92673,Q9H223,Q92581,Q9UEU0 12 +Exocytic vesicle 0.6680301320082812 2.984028798623421 0.0028447999497247 0.9270584543371656 0.0871457051265682 43 O43752,P50897,Q86Y82,Q92542,P51790,O15400,P11279,P05067,O43760,Q7L0J3 10 +Vacuolar membrane 0.6610706883687969 2.9025393385290097 0.0037015066822472 0.9668925153274356 0.1097317626124258 146 Q9BXS4,Q93050,Q99523,P42785,Q7Z3C6,Q16625,Q9BTU6,Q8IY95,P13473,P04062,O75955,P07602,O15400,Q9Y487,Q9Y3E7,Q8NCG7,Q8WTV0,P63096,Q9UEU0,O75503,P11117,P98155,Q9UIQ6,Q8IV08,Q99747,Q9NRA0,P51790,O95772,O00462,P10253,Q9Y6I9,Q86YV9,P51809,O95721,O15260,P10619,Q14108,P51798,Q86WC4,P98164,Q9NQ11,P01130,Q9NUM4,P08754,Q9NQX7,O75787,Q9NV96,Q13137,P11279,Q15043,Q99519,P42892,P27105,Q92542,P20645,Q8N511,O14678,Q9UNK0,P08195,P41440,Q07954,Q8TDY2,O15118,Q8NHS3 64 +Coated vesicle membrane 0.5914513605509444 2.8659559764171103 0.0041575205729917 0.978262707312815 0.119398793955608 64 P01130,P04439,Q8NDZ4,P01889,P10321,O43493,P20645,Q8N511,P02786,P24390,P00533,P11717,Q14108,Q9UEU0,P98164 15 +Snare complex 0.7599892698001105 2.833550962757067 0.0046033967115544 0.9855965706204538 0.1281976235732879 21 Q99747,Q9P2W9,O43752,Q86Y82,Q13190,O00161,O95249,Q9UNK0,O15400,O95721,P51809,Q5SQN1,Q9NZ43,Q9UEU0 14 +Clathrin coated endocytic vesicle membrane 0.7993989507063035 2.8174398780998873 0.0048408176766663 0.98843201628882 0.1308444542604811 17 P01130,Q14108,P20645,P02786,P00533,P11717,O43493,P98164 8 +Golgi associated vesicle 0.653184579768623 2.804034476786399 0.0050467508182643 0.9904355946920004 0.1325132571995692 36 Q99523,Q8NDZ4,Q8IUH4,Q8N511,Q9Y287,Q04656,P24390,P11717,P05067,O43493 10 +Clathrin coated endocytic vesicle 0.7232799780490872 2.758117460717082 0.0058135304085431 0.9952907408748426 0.1460397576471977 23 P01130,O43493,P20645,P02786,P00533,P11717,Q14108,P98164 8 +Transport vesicle membrane 0.620769644096701 2.754414274446931 0.005879729089169 0.995570280653766 0.1460397576471977 50 O43752,P04439,P01889,P10321,Q86Y82,P19021,Q92673,Q9NV96,P16870,O43760,Q9UEU0,Q7L0J3 12 +Endosome lumen 0.9532400452163292 2.735405130230629 0.0062303542756982 0.9967968051244231 0.1506761994570192 8 Q99538,Q9UIQ6,P07711,P07858,P05067 5 +Coated vesicle 0.5754673892778007 2.721234604395445 0.0065038585778158 0.9975127252704384 0.1532575905900716 100 Q99523,Q8NDZ4,P01889,P00533,P05067,Q5VW38,Q9UEU0,P53634,P24390,P51809,P11717,Q14108,P98164,P01130,P04439,P02786,O43493,P42892,Q9Y282,O43752,P10321,P20645,Q8N511 23 +Phagocytic vesicle membrane 0.6855324886967227 2.697518736787787 0.0069858353318346 0.9984075986624296 0.1565394289160557 28 Q93050,P04439,P01889,P10321,P51151,Q04656,P13473,Q06481,Q9Y487,P51809,P11279 11 +Clathrin coated pit 0.6527950848755608 2.695382974579524 0.0070307769870974 0.9984724727136522 0.1565394289160557 33 P01130,Q07954,P02786,P05067,P98164,P98155 6 +Tertiary granule 0.6247488437474942 2.689582715824343 0.0071541414738567 0.998637299378142 0.1565394289160557 44 Q93050,Q9Y2Q5,P42785,P27105,Q8WVQ1,O75874,Q15833,O75787,Q13510,Q4KMQ2,P10253,Q08722,P13473,O00161,O15400,Q92820,Q9Y6X5,P11279 18 +Trans golgi network 0.5378296530897028 2.663417998878212 0.0077351262015226 0.9992042428178884 0.1653158367255646 80 Q7Z3C6,Q9BTU6,Q9NX62,P04062,P05067,P19021,O15127,P53365,Q92673,P51809,P11717,Q4J6C6,Q8WWQ0,Q04656,P98194,O43493,O43752,Q8TCG2,P20645,Q9UNK0,Q9NPR9 21 +Clathrin coated vesicle 0.5918275731640622 2.629920438233923 0.0085404853182275 0.9996226788760112 0.1749347900318474 55 P42892,P01130,Q99523,O43752,Q14108,O43493,P20645,P02786,P00533,P51809,P11717,Q5VW38,P98164 13 +Clathrin coated vesicle membrane 0.6661808788794105 2.614087557208742 0.0089466105892239 0.9997410654436244 0.1749347900318474 29 P01130,O43493,P20645,P02786,P00533,P11717,Q14108,P98164 8 +Autophagosome membrane 0.7450164194611396 2.58701826244676 0.0096810461007716 0.9998689886904768 0.1779376273321838 18 Q7Z3C6,O75787,Q9Y6I9,P13473,Q9Y3E7,Q13137,P11279,Q8TDY2,Q9NQ11 9 +Endolysosome 0.8242298388998002 2.5355626716010753 0.0112266838056318 0.9999688181454776 0.1910615262476976 12 Q99538,P07711,P07858 3 +Golgi cisterna 0.6276045552167625 2.526426914391122 0.0115229361133437 0.9999763243290974 0.1925377870575076 33 Q9BXS4,Q99523,P04439,Q16706,O00461,Q8WVQ1,Q9P2E5,Q10472,P98194,O95249,O60512,Q12893,Q92673,Q8NBN3,Q8NBZ7,Q8N6G5 16 +Neuromuscular junction 0.6996610591607032 2.499073206356071 0.0124518585506316 0.9999900217209556 0.197476020667692 21 P17252,Q14168,P10644,Q15375,P17612,Q7L0J3,P05067,O43760,P05556 9 +Golgi lumen 0.91423489988975 2.49875278235578 0.0124631220878412 0.99999012576472 0.197476020667692 7 O00461,P05067,Q9NX62 3 +Multivesicular body 0.7882051930692693 2.4459755896464537 0.0144460780828681 0.9999984430348856 0.225016029799251 13 P07711,P10644,P00533,Q92673,Q9Y3E7,P11279,Q9NQ11 7 +Blood microparticle 0.7049031568113312 2.420927354927307 0.0154809706529686 0.9999994071271744 0.2335939508473346 19 P27105,P02786,P04062,O00560,Q08380 5 +Sarcolemma 0.6301635371318108 2.42001371368823 0.0155199217909982 0.999999428296655 0.2335939508473346 30 P35613,Q92542,Q96QD8,O75955,Q14118,P11166,P11279,P41440,Q9H9S5,P05556 10 +Late endosome membrane 0.5839682987146925 2.399603496566617 0.0164128393175224 0.9999997516809256 0.2394190370286213 45 Q9BXS4,Q8IV08,Q9NUM4,Q7Z3C6,Q9H7F0,O95772,P51790,O15118,P13473,Q92673,Q15043,Q9NV96,P51809,Q9UNK0,P11279,Q14108,Q9UEU0 17 +Intrinsic component of golgi membrane 0.7927208300086772 2.3910314224212796 0.0168011148770521 0.9999998272469002 0.2412535089376708 12 Q9Y282,O43505,Q8TB61,Q9Y5Z9,Q6ZRP7,P98194,Q8N6G5 7 +Presynapse 0.5518686940983544 2.3843650680949975 0.0171086207877235 0.9999998704079522 0.2413580412950414 108 Q9BTU6,Q13614,O75955,O15400,P05067,Q9UEU0,P17301,Q9BVK6,P50897,O75494,Q07021,P51790,O95721,P11166,O60716,P0DP25,P54920,Q13641,P56545,Q86Y82,O14936,P51116,Q5SQN1,P11279,Q7L0J3,O43752,Q99808,Q9UQB8,Q92542,O00161,P51114,Q06787,P41440,Q15833,O43760 35 +Autolysosome 0.9489247311827996 2.370665956054806 0.017756070623691 0.9999999292729131 0.2413580412950414 5 Q13772,Q13501,P11279,P13473 4 +Secondary lysosome 0.9489247311827996 2.370665956054806 0.017756070623691 0.9999999292729131 0.2413580412950414 5 Q13772,Q13501,P11279,P13473 4 +Trans golgi network transport vesicle 0.731606592743273 2.334404469328966 0.019574552989851 0.9999999871176736 0.2533663971503249 15 Q99523,O43493,Q04656,P11717 4 +Chloride channel complex 0.8701076461956966 2.3200257757373968 0.0203394830097081 0.9999999937124548 0.2570111537823396 7 Q86WC4,Q9C0H2,P51798,Q9H813 4 +Ficolin 1 rich granule membrane 0.6945281298684877 2.315979073846093 0.0205594112892439 0.999999994884694 0.2570111537823396 18 Q93050,P42785,P10253,P13473,Q9Y6X5,P11279 6 +Specific granule membrane 0.6825414696415922 2.2970845034053187 0.0216139496136915 0.999999998099265 0.2648429292664339 19 P06756,Q9Y2Q5,P30519,P27105,Q08722,Q4KMQ2,O00161,Q9NV96,P61225 9 +Golgi stack 0.5673711710261062 2.2614703516148955 0.0237301466199033 0.9999999997401524 0.2804535511175266 44 Q9BXS4,Q99523,P04439,Q16706,O00461,Q8WVQ1,Q9P2E5,Q10472,P98194,O95249,O60512,Q12893,Q92673,Q8NBN3,Q8NBZ7,Q10469,Q8N6G5 17 +Endosome membrane 0.6052396915668686 2.258654695426327 0.0239048726695727 0.9999999997795648 0.2804535511175266 157 Q9BXS4,Q93050,Q99523,P01889,O00461,Q7Z3C6,Q15904,Q9Y287,P13473,P00533,O15400,Q8N4V1,Q9Y487,Q9Y3E7,Q9H223,Q9UEU0,Q9H4M9,Q8IV08,O15127,Q9NYA4,P55899,Q99805,P51790,Q9H7F0,O95772,Q96J02,Q92673,Q06481,P51809,P11717,Q14108,Q9NQ11,P01130,Q9NPF0,P04439,Q9NUM4,Q86Y82,O75787,Q04656,P02786,Q9H3E2,Q9NV96,P11279,Q15043,P05556,P42892,P10321,Q92542,Q9BRG1,Q9UNK0,Q92783,Q92581,O15118 53 +Presynaptic active zone 0.6919769637019825 2.2578341066186467 0.0239560039788568 0.9999999997899256 0.2804535511175266 17 Q07021,O75955,P41440,P05067,Q7L0J3 5 +Golgi membrane 0.6172224183769328 2.255393673022027 0.0241086295302335 0.9999999998180475 0.2804535511175266 167 Q9BXS4,P33908,Q86SF2,O43505,Q8NDZ4,P01889,O00461,Q7Z3C6,Q8TB61,Q9Y287,P00533,Q8N4V1,Q7LGA3,P35613,Q8IV08,Q9BVK6,Q16706,Q8IUH4,Q6ZRP7,P51790,O95249,Q8IZA0,Q92673,P24390,Q9BQT9,O95721,P11717,P11166,O15260,Q6AZY7,Q14108,Q92896,P04439,Q9P2W9,P13591,Q15392,Q99640,Q86Y82,P08754,Q8NCH0,P98194,O43164,Q8NBN3,Q16739,O94766,Q8N6G5,Q9H0U4,Q04721,Q9Y282,O43752,Q5SRI9,P10321,Q9P2E5,Q10472,O60512,Q9H9S5 56 +Caveola 0.6903884306127339 2.24925064288104 0.024496554097952 0.9999999998737374 0.281404165200224 17 P41440,O75955,P11166,Q8WTV0,Q14254 5 +Tertiary granule membrane 0.744648767759093 2.237274401716086 0.0252684112031322 0.9999999999389968 0.2862290336696169 13 Q9Y2Q5,P27105,O75787,Q08722,Q4KMQ2,O00161,P10253 7 +Vesicle lumen 0.5752508830903134 2.232103750742009 0.0256081066039191 0.9999999999557172 0.2862290336696169 136 O75629,P14174,O00584,Q9BTY2,P00533,P06280,P15586,Q08380,P05067,P17900,P16278,P34059,P15289,P53634,P61916,Q9Y6I9,P07686,Q92820,P08236,P10619,P02792,Q8WVQ1,P04066,Q99519,O00754,O00560 26 +Platelet alpha granule 0.643389529414744 2.2284437923407627 0.0258509355762548 0.9999999999647824 0.2862290336696169 22 Q9Y6I9,Q06481,Q6YHK3,P05067,Q9UEU0,O60245 6 +Golgi apparatus subcompartment 0.5467599713897288 2.2233753467586146 0.0261905006597982 0.999999999974437 0.2865365488851734 116 Q9BXS4,Q99523,Q7Z3C6,O00461,Q9BTU6,Q9NX62,P04062,P05067,P19021,Q16706,O15127,P53365,O95249,Q92673,P51809,P11717,Q4J6C6,P04439,Q8WVQ1,Q8WWQ0,Q04656,P98194,Q8NBN3,O43493,Q8N6G5,O43752,Q8TCG2,Q9P2E5,P20645,Q10472,O60512,Q9UNK0,Q9NPR9,Q8NBZ7 34 +Endoplasmic reticulum golgi intermediate compartment membrane 0.6047390523762803 2.21645971200481 0.0266600341322449 0.9999999999835892 0.2866818059605117 29 Q9BVK6,Q9Y282,P53634,Q10472,Q15904,Q13190,Q8N511,P24390,O15260,Q9Y6N7,Q9H0U4 11 +Phagophore assembly site 0.7398656299371555 2.214016016609725 0.0268276771627899 0.999999999985992 0.2866818059605117 13 Q7Z3C6,Q86Y82,Q13501,P51149,Q6PHR2,Q8TDY2,Q9H0U4 7 +Integral component of synaptic vesicle membrane 0.9019846539459316 2.1877708071897515 0.0286863013543334 0.9999999999975824 0.2995762607344598 5 O43752,Q7L0J3 2 +Plasma membrane raft 0.6113930513388429 2.166849506144346 0.0302463311721572 0.999999999999448 0.3088486483023612 26 P17252,P41440,P10644,O75955,Q14118,P17612,P11166,Q8WTV0,Q14254,P05026 10 +Vacuole 0.7026483074614798 2.149410994429753 0.0316018346816893 0.9999999999998472 0.319143802994203 261 Q9BXS4,O14773,Q9UMR5,P07711,O75629,Q9HAT2,P07858,Q9UM22,Q13501,Q8NHP8,O00584,Q9BTY2,P13473,O00115,P07602,P06280,P15586,P17900,O75503,P11117,P98155,Q99538,Q9UIQ6,Q8IV08,P16278,P34059,P50897,P54802,P53634,P06865,P61916,P51790,Q13510,O00462,P10253,P07686,Q92820,P08236,Q13772,P10619,Q14108,Q01459,Q86WC4,P98164,P01130,Q9NUM4,Q9NQX7,Q13137,P11279,Q8NCC3,P04066,Q99519,P42892,O00754,P27105,Q92542,O00560,Q07954,O15118,Q8NHS3,Q99523,P42785,Q16625,P04062,Q8WTV0,Q9UBX1,Q9UHG3,P15289,Q9Y6I9,P38571,O15260,P51798,P02792,P51688,Q9NV96,Q15043,P20645,Q8N511,Q9UNK0,P08195,P41440,Q93050,Q7Z3C6,Q9BTU6,Q8IY95,O75955,O15400,Q9Y487,Q9UEU0,Q9NRA0,O95772,P51809 92 +Lumenal side of membrane 0.7908023630782122 2.1375810339678876 0.0325507624108631 0.999999999999938 0.3205946833524824 9 P10321,P10619,P04439 3 +Platelet alpha granule membrane 0.8875827042331154 2.130912583921909 0.033096344483789 0.9999999999999633 0.3205946833524824 5 Q06481,Q6YHK3 2 +Golgi cisterna membrane 0.6123990565596787 2.12046376833341 0.0339669539066211 0.999999999999984 0.3205946833524824 24 Q99523,O00461,Q8WVQ1,O60512,Q8NBN3,Q8NBZ7,Q8N6G5 7 +Intrinsic component of postsynaptic density membrane 0.8842464196598865 2.1176918294153584 0.034201175285272 0.9999999999999872 0.3205946833524824 5 Q9BQT9 1 +Specific granule 0.5507705821043554 2.114524201975704 0.0344705199064383 0.99999999999999 0.3205946833524824 42 P06756,Q9Y2Q5,P30519,P27105,Q8WVQ1,P51790,Q08722,Q4KMQ2,O00161,Q92820,Q9NV96,P61225,Q15833,Q99519 14 +Nuclear envelope lumen 0.855834965438484 2.105658599189989 0.0352340185186079 0.9999999999999952 0.3205946833524824 6 P05067,Q92673 2 +Cis golgi network 0.6380514862117351 2.09167388534472 0.0364676981274378 0.9999999999999986 0.3254671221170905 20 Q16706,O00461,O95249,P24390,Q9NPR9,O94766,Q9UNK9 7 +Gtpase complex 0.8480774401720848 2.0741771769645085 0.0380628590425813 0.9999999999999996 0.3254671221170905 6 P08754,P09471,Q14344,P04899,P63096 5 +Synaptic vesicle membrane 0.6634332590560537 2.0632026988723915 0.0390933738377801 1.0 0.3254671221170905 16 O43752,Q86Y82,O00429,P51149,P20337,P0DP25,O43760,Q7L0J3 8 +Copii coated er to golgi transport vesicle 0.5551873212492294 2.0607682613041916 0.0393251537856462 1.0 0.3254671221170905 34 Q9Y282,P04439,P53634,P01889,P10321,P05067 6 +Receptor complex 0.5605866319323682 2.0589801672612253 0.0394961384279111 1.0 0.3254671221170905 33 P17301,P01130,P06756,P05556,Q04721,Q07954,P29317,P02786,P00533,Q15375,O00560,O14786,P05067,P51805,P98164,P98155 16 +Neuron spine 0.5498996960438098 2.022129553103766 0.0431629696460884 1.0 0.3451401816019893 34 Q9UQB8,O75787,Q13614,Q14168,P51114,Q9Y4F1,Q06787,P51116,P17612,O60716,P05067,P46934,P05556 13 +Messenger ribonucleoprotein complex 0.8337813005335883 2.0158766206377923 0.04381287890665 1.0 0.3471037561656158 6 Q06787,P67809,Q99729 3 +Intrinsic component of postsynaptic specialization membrane 0.8262660679340508 1.9850824157447984 0.047135302841057 1.0 0.3587834984006897 6 Q9BQT9 1 +Golgi medial cisterna 0.8509315978857147 1.98467304137534 0.0471808600527232 1.0 0.3587834984006897 5 Q9BXS4,P04439,O95249 3 +Ciliary base 0.7729161579075242 1.9841494971789344 0.0472391766120603 1.0 0.3587834984006897 8 P10644,A0AVF1,P17612,P22694 4 +Multivesicular body membrane 0.7810294854692318 1.9471288997336176 0.0515192830558763 1.0 0.3757636597488127 7 Q92673,Q9Y3E7,Q9NQ11 3 +Lumenal side of endoplasmic reticulum membrane 0.7756942397779825 1.924284180533278 0.0543189723824897 1.0 0.3798377349673094 7 P10321,P04439 2 +Filopodium 0.5278265764821607 1.9223815965370332 0.054557759538286 1.0 0.3798377349673094 40 Q14517,P06756,P51114,O00592,Q14118,Q9Y4F1,P51116,P78310,P05067,P05556 10 +Extrinsic component of cytoplasmic side of plasma membrane 0.5985373139857749 1.9046249673242597 0.0568288387214386 1.0 0.3868570576666822 21 Q96CP6,P08754,P09471,Q14344,Q9Y4F1,P04899,P63096,P07947,P29992,Q9H0H5 10 +Basement membrane 0.7058116754608936 1.8989714361816432 0.0575682316939782 1.0 0.3890088597556327 11 P14543,Q5SZK8,Q14118,O14936,O75882 5 +Sorting endosome 0.870785736232444 1.8632260606768232 0.062430467796307 1.0 0.4089224400723579 4 P01130 1 +Cell projection membrane 0.4572731677568614 1.8610295458579476 0.0627400044071844 1.0 0.4089224400723579 80 Q14344,P00533,P55011,Q9H4M9,P06756,P51790,Q14168,Q06481,O60266,O95721,Q13325,P98164,P29317,O75787,Q04656,O14936,P05556,P31751,O00592,Q12959,P41440 21 +Intrinsic component of synaptic vesicle membrane 0.7119765145378076 1.8539805005317944 0.0637419497546805 1.0 0.4118394058848395 10 O43752,Q7L0J3 2 +Plasma membrane protein complex 0.4540659356995599 1.8436982341828667 0.0652271305232343 1.0 0.4118394058848395 79 P01889,P19022,Q14344,Q14118,O75955,P00533,P63096,P17301,P06756,Q07666,P04899,O60716,P0DP25,P29992,P04439,P62993,P08754,P09471,P02786,Q14254,P05556,P17252,Q92859,Q9NR28,P10321,Q92542,O14678,Q12959,O00560,P08195,P41440,Q07954,P05026 33 +Ficolin 1 rich granule 0.472757160998307 1.8328797858889456 0.0668204504764327 1.0 0.4118394058848395 92 Q93050,P16278,P42785,P07858,Q8WVQ1,Q13510,P10253,P13473,P15586,P08236,Q9Y6X5,P11279 12 +Organelle envelope lumen 0.5169999605382785 1.8325164504295812 0.0668745131503782 1.0 0.4118394058848395 39 O95831,P51970,O00584,Q92673,P11717,P05067 6 +Glial cell projection 0.8131963228602582 1.8318759779861633 0.0669699002457653 1.0 0.4118394058848395 5 P05067,P05556 2 +Trans golgi network membrane 0.5431239818386514 1.8278331711480755 0.0675745932245928 1.0 0.4118394058848395 30 O43752,O15127,P53365,P20645,Q04656,Q9NX62,P11717,P05067 8 +Proton transporting v type atpase v0 domain 0.8617003163561077 1.8271610910750695 0.0676755521039602 1.0 0.4118394058848395 4 Q93050,Q9Y487 2 +Vacuolar proton transporting v type atpase v0 domain 0.8617003163561077 1.8271610910750695 0.0676755521039602 1.0 0.4118394058848395 4 Q93050,Q9Y487 2 +Crd mediated mrna stability complex 0.787395281672802 1.82423155769319 0.0681170725729005 1.0 0.4118394058848395 6 P67809 1 +Schaffer collateral ca1 synapse 0.617778569581881 1.8113781770265036 0.0700823316959113 1.0 0.4206885765258936 16 Q9BVA1,Q9UQB8,Q15375,O14936,O60716,P47756,P05556 7 +Intrinsic component of vacuolar membrane 0.854340231120652 1.7978721258759374 0.0721972742455578 1.0 0.422606974723998 4 P13473,O15118,Q9NQ11 3 +Acrosomal membrane 0.8530229396989915 1.7926233400183638 0.0730331717902155 1.0 0.424794208070937 4 P35613,Q08431 2 +Protein lipid complex 0.7427674679437252 1.782063238444541 0.0747389197909125 1.0 0.4308550482425512 7 P01130,P98155 2 +Endoplasmic reticulum golgi intermediate compartment 0.487552626952948 1.7729941741508406 0.076229672239074 1.0 0.4351246508553358 56 P33908,Q9BVK6,Q9Y282,P53634,P80303,Q10472,Q15904,Q13190,Q8N511,P24390,O15260,Q9Y6N7,Q9H0U4,Q02818 14 +Golgi associated vesicle membrane 0.5605087449309374 1.7676760279945931 0.0771150797753175 1.0 0.4372524289775422 23 P24390,Q8IUH4,Q8NDZ4,Q9Y287 4 +Ciliary membrane 0.7220735628623596 1.7596932283891713 0.0784598345801519 1.0 0.438440308460606 8 Q9H4M9,Q15019,O14936,O60266,O95721 5 +Phagophore assembly site membrane 0.7709400471322796 1.7553704432785122 0.0791959643138853 1.0 0.438440308460606 6 Q8TDY2,P51149,Q9H0U4,Q7Z3C6 4 +Amphisome 0.7924496815543963 1.746962598090766 0.0806438261375439 1.0 0.4437824923377418 5 Q13501 1 +Endolysosome lumen 0.9919398173025252 1.740544837871709 0.0817633940475854 1.0 0.4472652329150658 3 P07711,P07858 2 +Platelet dense granule 0.8377570297607706 1.7316524466848249 0.0833354621630557 1.0 0.4505017042814602 4 P13473 1 +Camp dependent protein kinase complex 0.7850508023018509 1.716534002875716 0.086064350029531 1.0 0.4519607867265088 5 P10644,P17612,P22694 3 +Cell trailing edge 0.7549776419029754 1.688158990577468 0.0913807130552226 1.0 0.453597209119849 6 O75955,P41440 2 +Flotillin complex 0.720854318429468 1.6862767965381162 0.0917424980966881 1.0 0.453597209119849 7 O75955,P41440 2 +Dendritic shaft 0.7152898128032816 1.6618153047659472 0.0965498125858888 1.0 0.453597209119849 7 Q14168,P05067,Q96J84 3 +Ruffle membrane 0.493542533142753 1.6386562911469047 0.1012848618185879 1.0 0.453597209119849 36 P06756,P29317,P51790,P00533,Q06481,P05556 6 +Mhc class i protein complex 0.9642665233745296 1.6362598125345986 0.1017852230537614 1.0 0.453597209119849 3 P10321,P04439 2 +Mhc protein complex 0.9642665233745296 1.6362598125345986 0.1017852230537614 1.0 0.453597209119849 3 P10321,P04439 2 +Ciliary transition zone 0.6515543244362593 1.6361574862297443 0.1018066315111769 1.0 0.453597209119849 11 P41208,Q92845,A6NIH7,Q15019,Q9HCM3 5 +Tim23 mitochondrial import inner membrane translocase complex 0.7644260195922258 1.6313333682653155 0.102819996148237 1.0 0.453597209119849 5 Q99595,Q3ZCQ8 2 +Photoreceptor connecting cilium 0.6928222386359045 1.6281738378599333 0.1034880305170253 1.0 0.453597209119849 8 Q15019,Q9HCM3,P41208,Q92845 4 +Dendrite membrane 0.8106282939304525 1.622700535253986 0.1046534369253961 1.0 0.453597209119849 4 Q14168 1 +Apicolateral plasma membrane 0.7059713641181903 1.6207310692344217 0.1050753273268418 1.0 0.453597209119849 7 P19022,Q16625,P46934,P78310 4 +Main axon 0.6220779191813333 1.6198037729635135 0.1052744355603794 1.0 0.453597209119849 13 P05067,Q14118 2 +Perikaryon 0.5246709763236094 1.6153966546552625 0.1062248242423264 1.0 0.453597209119849 27 Q9BTU6,Q04656,Q14168,Q06787,P05067,P19021 6 +Collagen trimer 0.9503088906795656 1.613826599080019 0.1065650433197804 1.0 0.453597209119849 2 Q5KU26 1 +Mcrd mediated mrna stability complex 0.8072478869470641 1.6090757766699304 0.1075997732188542 1.0 0.453597209119849 4 O60506 1 +Cytolytic granule 0.7340682979295194 1.59953902129212 0.1097008854041876 1.0 0.4541221337227408 6 P30740,Q01085,Q9NVJ2,Q15833,P11279 5 +Proton transporting v type atpase complex 0.627175107937576 1.5863480904280365 0.1126603688617502 1.0 0.4591731627886091 12 Q93050,Q9Y487,Q15904,Q8N511 4 +Acrosomal vesicle 0.5380940579508507 1.57295583183559 0.1157290457433022 1.0 0.4591731627886091 22 P35613,P45880,Q08431,P07686,Q14254,Q9Y487,P17612,P78310,Q9H0H5 9 +Actin based cell projection 0.4648527480397696 1.569519107208168 0.1165270308475914 1.0 0.4591731627886091 56 Q14517,P06756,Q00013,Q04656,P51114,O00592,Q14118,Q9Y4F1,P51116,P78310,P05067,P05556,Q9Y6M7 13 +Microvillus membrane 0.7466344458764784 1.5574228536651658 0.1193701236662432 1.0 0.4641974100661477 5 O00592 1 +Presynaptic membrane 0.5415921961835997 1.550368117751168 0.1210531863212829 1.0 0.4641974100661477 21 Q96CX2,P19022,Q9BTU6,Q9Y639,Q92542,Q06787,Q05193,P09496,O14936,Q14160,P35222 11 +Leading edge membrane 0.4718686575881218 1.550342296537082 0.1210593804658348 1.0 0.4641974100661477 50 P06756,P29317,P51790,O75787,Q14168,P00533,Q06481,P05556 8 +Hippocampal mossy fiber to ca3 synapse 0.7889982820637693 1.535359512516762 0.1246955431275385 1.0 0.4641974100661477 4 O60716,Q15375 2 +Intrinsic component of endoplasmic reticulum membrane 0.4513947278146925 1.5349910005276337 0.1247860386493704 1.0 0.4641974100661477 61 Q96CP6,Q86XL3,Q9Y282,P04439,O95470,P01889,Q8TB61,P10321,Q86YN1,Q5H8A4,O75844,Q8N4V1,Q15629,Q9UBM7 14 +Postsynaptic density membrane 0.6301513192430527 1.5305044438906843 0.1258919143392076 1.0 0.4646372260149872 11 Q15375,Q9BQT9 2 +Tertiary granule lumen 0.5646882130056858 1.509240243022001 0.1312373994792808 1.0 0.4748313784309412 16 Q92820,Q13510 2 +Dendrite cytoplasm 0.6101164693219102 1.4992102721561047 0.133819091031806 1.0 0.4766656769698826 12 P33176,Q9UQB8,Q15334,Q14254,Q00577 5 +9plus2 motile cilium 0.5140794345867241 1.4624510805828663 0.1436176404785722 1.0 0.4961827503752178 23 P41208,Q9GZT3,P17252,Q13501,Q15019,P10644,P17612,P05026,P47756 9 +Cortical endoplasmic reticulum 0.7682446372131686 1.451251538224941 0.1467098304268765 1.0 0.503083336426491 4 Q9H2C2 1 +Myofilament 0.6975373407577496 1.443313763848136 0.1489321042489817 1.0 0.5053174521923685 6 P28289,Q9NYL9,Q13049 3 +Pore complex 0.6239458880394348 1.4347389079393575 0.1513615125240051 1.0 0.5053174521923685 10 P21796 1 +Perinucleolar compartment 0.7632758050422108 1.4310804448461938 0.1524071610622654 1.0 0.5053174521923685 4 Q92673 1 +Atpase dependent transmembrane transport complex 0.7140124508088663 1.4210686198589624 0.1552968115946182 1.0 0.5056678869854042 5 Q9NUT2,P05026,O14678 3 +Integrin complex 0.9065018807092956 1.4176455478012568 0.1562942751043121 1.0 0.5056678869854042 3 P17301,P06756 2 +Protein complex involved in cell adhesion 0.9065018807092956 1.4176455478012568 0.1562942751043121 1.0 0.5056678869854042 3 P17301,P06756 2 +Endosome 0.6297041293715334 1.413716486825331 0.1574451626019006 1.0 0.5059164490599536 265 Q9BXS4,O14773,P07711,P07858,Q13501,Q9Y287,P13473,P07602,P05067,Q99538,Q9UIQ6,Q8IV08,P55899,P51790,Q13510,Q92673,Q06481,P11717,Q14108,P98164,P01130,Q9NPF0,P04439,Q9NUM4,P02786,P11279,O43493,P42892,O43752,P10321,Q92542,Q07954,Q92581,O15118,Q99523,P01889,O00461,Q15904,Q5VW38,Q9NYA4,Q99805,Q9H7F0,P10644,Q86Y82,Q9NV96,O14786,Q15043,Q8TCG2,P20645,O60291,Q9BRG1,Q9UNK0,P41440,Q93050,Q7Z3C6,Q9BTU6,Q8IY95,P23458,O75955,P00533,O15400,Q9Y487,Q9H223,Q9UEU0,Q9ULH0,Q9Y2I1,P35613,Q9BXW6,O95772,Q96J02,P51809,Q9NQ11,O75787,Q04656,Q9H3E2,Q14254,P05556,Q9UKS6,P31751,Q92783,Q92544,Q9Y6W5,Q9NWW5,Q8N4V1,Q9Y3E7,Q9H4M9,O15127 87 +Postsynaptic specialization intracellular component 0.7567858102660501 1.4047190551868625 0.1601048371710254 1.0 0.5108900880561541 4 O60716,Q9UQB8,P35222 3 +Postsynaptic density intracellular component 0.7567858102660501 1.4047190551868625 0.1601048371710254 1.0 0.5108900880561541 4 O60716,Q9UQB8,P35222 3 +Platelet dense granule lumen 0.8847703464947769 1.3458143262376925 0.1783624040203515 1.0 0.5320504902399219 2 Q08380 1 +Triglyceride rich plasma lipoprotein particle 0.8872334901118862 1.3446777455320575 0.1787293244074421 1.0 0.5320504902399219 3 P98155 1 +Outer mitochondrial membrane protein complex 0.5315812767338296 1.3441917709539624 0.1788863819984516 1.0 0.5320504902399219 17 Q15388,Q9NVH1,Q9NX63,Q9NS69,Q13505,Q8N4H5,Q5XKP0,Q8IWA4 8 +Semaphorin receptor complex 0.8866200967221911 1.3423562523664438 0.1794805122384815 1.0 0.5320504902399219 3 P51805,O14786 2 +Dendritic tree 0.4658422458671292 1.320098168257417 0.1868022442735131 1.0 0.5449881348805032 122 Q9P265,Q9BTU6,Q96QD8,Q13740,Q13614,P05067,P50897,P33176,O75494,Q14168,P04899,Q9BQT9,P17612,P98179,O60716,Q99729,Q13641,P98164,P21964,O75787,Q04656,Q9Y4F1,P51116,Q14254,P46934,Q7L0J3,P05556,Q96J84,Q9UQB8,P51114,Q15375,Q06787 32 +Cis golgi network membrane 0.8761751275852886 1.3107921406331635 0.1899279985657809 1.0 0.5488799706979643 2 Q9NPR9 1 +Anchored component of membrane 0.5722124784817879 1.3032143280130737 0.1925015998608208 1.0 0.5494067399754482 12 Q92485,Q6YHK3 2 +Meiotic spindle 0.725935305462859 1.279284917669044 0.2007967417986929 1.0 0.5574991109154042 4 O14965,Q8IXJ6 2 +Escrt complex 0.5877359385694546 1.2578543421792852 0.20844443849071 1.0 0.5678189523233949 10 Q9UK41,Q9BRG1,Q92783,Q9Y3E7,O14964 5 +Lamellipodium 0.3949016955529293 1.2574260992606732 0.2085993834249515 1.0 0.5678189523233949 73 Q14517,P06756,Q9Y6W5,P19022,P29317,Q9UQB8,O00592,O75955,Q14118,O00213,P51809,P41440,O60716,P05067,O00571,Q14254,P05556 17 +Cell cell junction 0.4646034229681933 1.2513094636913609 0.2108215940499587 1.0 0.5681672871903579 126 Q9Y6W5,P19022,Q16625,O75955,Q14118,Q13308,Q5T2T1,P05067,Q9Y624,Q14517,Q14168,P11166,O60716,Q96RD7,P62993,Q9NZW5,Q9BY67,Q14574,P29317,O14936,P61225,P31949,P41440,Q14254,Q7L0J3,P05556,Q14126,Q96J84,Q00013,Q9UQB8,O00192,Q6IQ23,O00161,O00592,Q12959,O00560,P78310,Q86VI3,P05026,Q92692 40 +Intrinsic component of organelle membrane 0.4932575813816661 1.245598402434522 0.2129118691012268 1.0 0.5721228295439399 149 Q86XL3,O43505,P01889,Q9Y5Z9,Q8TB61,Q9H9P8,Q5H8A4,P51149,Q9Y287,P13473,Q8N4V1,Q15629,Q8IWA4,Q96NB2,Q8IWT6,O95470,Q6ZRP7,Q9NQ11,Q10471,Q9UBM7,Q96CP6,Q9Y5Y5,Q9NVH1,P04439,Q9NWR8,Q9BUB7,Q03519,Q86Y82,Q86YN1,O14925,Q13505,O75880,P98194,O75844,Q99442,Q9Y2R0,Q8N6G5,Q7L0J3,P42892,Q9Y282,O43752,Q99595,P10321,P17152,O15118,Q9UG56,Q9Y3D6,Q5XKP0 48 +Er to golgi transport vesicle membrane 0.4816820483012738 1.2438860487444166 0.2135415047019206 1.0 0.5721418158048546 23 P10321,P04439,P01889 3 +Integral component of lysosomal membrane 0.8541106931757096 1.2195681390850115 0.2226286305891651 1.0 0.586264440318968 3 O15118,Q9NQ11 2 +Guanyl nucleotide exchange factor complex 0.6639048271109442 1.2103196480566425 0.226156261155761 1.0 0.5892878932903334 5 Q14185,Q9Y2Q5 2 +Postsynaptic specialization membrane 0.5233438294088226 1.2031252429479653 0.2289278583449827 1.0 0.5896110229049321 15 Q15375,Q9BQT9 2 +Juxtaparanode region of axon 0.7052299603954562 1.1951459195191938 0.2320300236791093 1.0 0.5923210882252818 4 Q14168,Q15334 2 +Centriolar satellite 0.45683961172432 1.17555140845102 0.2397741826561976 1.0 0.5996674399202122 29 Q86UY6,Q00013,O00592,O75955,Q14145,P41440 6 +Presynaptic active zone membrane 0.6545294152267989 1.1708403501815972 0.2416629554037526 1.0 0.5996674399202122 5 P19022,Q9Y639,P20020 3 +Integral component of presynaptic active zone membrane 0.6545294152267989 1.1708403501815972 0.2416629554037526 1.0 0.5996674399202122 5 P19022,Q9Y639,P20020 3 +Intrinsic component of presynaptic active zone membrane 0.6545294152267989 1.1708403501815972 0.2416629554037526 1.0 0.5996674399202122 5 P19022,Q9Y639,P20020 3 +Brush border membrane 0.5562523530010234 1.158653614846934 0.2465974052179675 1.0 0.5996674399202122 11 P98164,Q14344,Q04656,P41440 4 +Intrinsic component of mitochondrial inner membrane 0.4408210562698441 1.1551556697309389 0.2480266845170613 1.0 0.5996674399202122 33 Q9NVH1,Q9NWR8,Q9NX63,Q99595,Q9H9P8,P17152,O14925,Q13505,O75880,P50336,Q9UG56,Q9Y2R0,Q5XKP0,Q96NB2 14 +Zonula adherens 0.6287170377182826 1.1458105846598627 0.251873534611569 1.0 0.601280909912447 6 O60716,Q92692 2 +9plus0 non motile cilium 0.5022610003281334 1.1427102811846224 0.2531588997134955 1.0 0.601280909912447 16 P35613,P41208,Q92845,Q15019,Q9HCM3,P29992 6 +Specific granule lumen 0.4933531543952745 1.1407870726899492 0.2539585414794141 1.0 0.601280909912447 18 Q92820,Q99519 2 +Cell pole 0.8315831576386947 1.1349479931031086 0.2563971094855386 1.0 0.601280909912447 3 P08195 1 +Node of ranvier 0.8246778567379055 1.1091226678199648 0.267377267337429 1.0 0.6053503474852706 3 Q14118 1 +Secretory granule 0.6058390769063202 1.1091101988295136 0.2673826456991461 1.0 0.6053503474852706 273 Q93050,P07711,O75629,P42785,P14174,P07858,P01889,P30519,O00584,Q9BTY2,P13473,O15400,P07602,P06280,P15586,Q08380,P16870,P05067,P17900,Q9Y487,P19021,Q9UEU0,P48960,P35613,P06756,P16278,P34059,P15289,P53634,P06865,P61916,P51790,Q13510,O00462,P10253,Q9Y6I9,P07686,Q92820,Q06481,P51809,P08236,P11717,O15260,P10619,P02792,Q8WVQ1,Q9NQX7,O75787,Q08722,Q04656,Q9NV96,Q9Y6X5,P11279,P04066,O60245,Q99519,P42892,O00754,P27105,P10321,P45880,Q08431,Q92542,O00560,P78310,Q6YHK3 66 +Lamellar body 0.8248724147193127 1.10350834958286 0.2698064676208993 1.0 0.6092190263970675 2 Q07065 1 +Dopaminergic synapse 0.8226353323176416 1.1014958055494433 0.2706809290237348 1.0 0.6096955239529714 3 P41440 1 +Ficolin 1 rich granule lumen 0.3776578462268314 1.0951245336035795 0.2734620817990814 1.0 0.6106790075989152 74 P16278,P07858,Q8WVQ1,Q13510,P08236,P15586 6 +Lamellipodium membrane 0.5882853374696482 1.0920557096039445 0.2748086152467484 1.0 0.611499073636227 7 P29317 1 +Sperm connecting piece 0.8205748052645894 1.0863379971509388 0.2773294820529406 1.0 0.6115947824726597 2 P10644 1 +Platelet dense tubular network membrane 0.8200376040827324 1.0841944177774148 0.2782786062163374 1.0 0.6115947824726597 2 Q9H4M9 1 +Platelet dense tubular network 0.8200376040827324 1.0841944177774148 0.2782786062163374 1.0 0.6115947824726597 2 Q9H4M9 1 +Histone pre mrna 3 end processing complex 0.8176535692489961 1.0829184342408629 0.2788446287878612 1.0 0.6115947824726597 3 P67809 1 +Striated muscle thin filament 0.631510516392668 1.0740488751197512 0.2828007765954046 1.0 0.61879503259804 5 P28289,Q9NYL9 2 +Platelet alpha granule lumen 0.5102225652060914 1.071839698913847 0.2837920386403003 1.0 0.6194890344665939 14 Q9Y6I9,P05067,Q9UEU0 3 +Neuron projection terminus 0.4764014561301691 1.0357727316995888 0.300308181800182 1.0 0.6315356028591915 18 P17301,O75494,P51790,Q06787,Q13641 5 +Adherens junction 0.4105558859733479 1.031780242190825 0.3021750770444564 1.0 0.6315356028591915 53 P19022,P31949,Q9UQB8,O00192,O00161,Q6IQ23,Q12959,O75955,Q14118,O00560,P78310,P41440,O60716,Q14254,Q92692 15 +Atp binding cassette abc transporter complex 0.8066075745366761 1.030817054669504 0.3026266190110112 1.0 0.6315356028591915 2 O14678 1 +Photoreceptor inner segment 0.5630396966443115 1.0292666066190153 0.3033544106521457 1.0 0.6315356028591915 8 P35613,Q15555,P11166 3 +Proton transporting two sector atpase complex proton transporting domain 0.5289480645718666 1.0194429331881183 0.3079927324863847 1.0 0.6327975458734171 11 Q93050,Q9Y487 2 +Wash complex 0.6592695307205872 1.0094896514861422 0.3127398621525072 1.0 0.634087061926989 4 P47756 1 +Proton transporting two sector atpase complex 0.4426289013623163 0.9871904033520116 0.323549305489516 1.0 0.634087061926989 24 Q93050,Q8N511,Q15904,Q9Y487 4 +Cytosolic region 0.5637482419304735 0.9809087473436884 0.3266377434641305 1.0 0.634087061926989 7 Q14118,P56545 2 +Neuronal ribonucleoprotein granule 0.7844650127859966 0.9602408630052957 0.3369340053244198 1.0 0.634087061926989 3 Q99729 1 +Copi coated vesicle 0.4781403270451181 0.9422127762150364 0.3460837140574755 1.0 0.642527137815798 15 P24390,Q8NDZ4 2 +Copi coated vesicle membrane 0.486605165406612 0.9394866598338056 0.3474809382394539 1.0 0.643820528713827 14 P24390,Q8NDZ4 2 +Amphisome membrane 0.6389168166586036 0.9282545475800964 0.3532755452787284 1.0 0.6480847458252235 4 Q9Y3E7 1 +Phosphorylase kinase complex 0.7770615095353421 0.9151028190410894 0.3601376551976436 1.0 0.6527637079301469 2 Q93100 1 +Glutamatergic synapse 0.3645085314762613 0.9122216579190116 0.3616520450611462 1.0 0.6527637079301469 76 P41440,Q07021,P51790,P51114,O75955,Q14118,P10644,Q9Y4F1,Q9BQT9,Q15375,O14786,Q7L0J3,Q14254,P56545 14 +Tight junction 0.4221390341898614 0.8980563713733132 0.3691554970562096 1.0 0.6536684042286256 28 P29317,Q16625,Q9Y624 3 +Organelle membrane contact site 0.444638769913 0.8890462723516446 0.3739782120436894 1.0 0.6581725142313095 20 Q96CP6,Q15388,Q9BXW6,Q96N66,O95772,Q8NEN9,Q5XKP0,O43865 8 +Neuron projection membrane 0.5220503290639336 0.8878585959716936 0.3746168187785117 1.0 0.6581725142313095 9 Q14168 1 +Apical junction complex 0.4066984933960368 0.8834014313035584 0.3770194177291692 1.0 0.6599635140821076 33 Q16625,Q6IQ23,Q12959,Q5T2T1,P78310,P61225,O60716,Q9Y624,Q92692 9 +Cell body 0.4215888952701855 0.8736153179244253 0.3823277814283292 1.0 0.6659283890832688 120 O14965,Q9P265,Q9BTU6,Q96QD8,Q13740,P05067,Q9UEU0,P19021,P50897,O75494,Q14168,Q92673,O94898,P04899,Q9NQ11,O75787,Q04656,P10586,P51116,Q7L0J3,Q9UQB8,P51114,Q15375,Q06787,P08195,P78310 26 +Extrinsic component of plasma membrane 0.3995574952282346 0.8732079587504343 0.3825497376112983 1.0 0.6659283890832688 42 Q96CP6,P08754,P09471,P19022,Q08431,Q15334,Q9H1P3,Q14344,Q9Y4F1,Q06787,P04899,P63096,O60716,P07947,P29992,Q9H0H5,P35222 17 +Presynaptic active zone cytoplasmic component 0.5832787639086554 0.8731141554761632 0.382600859016285 1.0 0.6659283890832688 5 O60716,P35222,P56545 3 +Respirasome 0.399277503907762 0.8697919290372348 0.3844141229626483 1.0 0.6678196200428616 41 Q6DKK2,O43676,P51970,O75306,Q13423,Q7KZN9,O96000,Q9Y6M9 8 +Pronucleus 0.5626925769399009 0.8610766578194721 0.3891958242166968 1.0 0.6710524623923909 6 O14965,O43823,P11166 3 +Female pronucleus 0.6190859301778174 0.850033540257607 0.3953064391418133 1.0 0.6803120179238322 4 O43823,P11166 2 +Secretory vesicle 0.602095720893347 0.8461348503611427 0.3974775210990475 1.0 0.6827697979252798 302 Q93050,P07711,O75629,P42785,P14174,P07858,P01889,P30519,O00584,Q9BTY2,P13473,O15400,P07602,P06280,P15586,Q08380,P16870,P05067,P17900,Q9Y487,P19021,Q9UEU0,P48960,P35613,P16278,P34059,P50897,P15289,P53634,P06865,P61916,P51790,Q13510,O00462,P10253,Q9Y6I9,P07686,Q92820,Q06481,P08236,P11717,O15260,P10619,P02792,Q8WVQ1,Q86Y82,Q9NQX7,Q08722,Q9NV96,Q9Y6X5,P11279,P04066,Q7L0J3,Q99519,P42892,O00754,O60245,O43752,P27105,P10321,P45880,Q08431,Q92542,O00560,P78310,Q6YHK3,O43760 67 +Somatodendritic compartment 0.465181043908324 0.7999365827484459 0.4237475409829867 1.0 0.7151182200059629 161 O14965,Q9P265,Q9BTU6,Q96QD8,Q13740,Q13614,P55011,P05067,P19021,Q9UEU0,P50897,P33176,O75494,Q14168,Q92673,O94898,P04899,Q9BQT9,P17612,O60716,P98179,Q99729,Q9NQ11,Q13641,P98164,P01130,P21964,O75787,Q04656,P10586,Q9Y4F1,P51116,Q14254,P46934,Q7L0J3,P05556,Q96J84,Q9UQB8,P51114,Q15375,Q06787,P08195 42 +Cornified envelope 0.5227785263833384 0.7967583760879335 0.4255913733988996 1.0 0.7151182200059629 7 Q14574 1 +Motile cilium 0.3984568355787748 0.773296095253784 0.4393471661465671 1.0 0.7314493581316941 31 Q15388,P41208,Q9GZT3,P17252,Q13501,Q15019,P10644,P17612,P05026,P47756 10 +Cell cell contact zone 0.4066784160983208 0.768522928668198 0.4421765740361765 1.0 0.7321806694400832 27 Q14126,P41440,Q12959,O75955,Q92692,P61225,Q14254,P05026,P11166,P05556 10 +Non motile cilium 0.4214355436121068 0.7651781549328982 0.4441654658919369 1.0 0.7331014201949869 21 P35613,P41208,Q92845,Q15019,Q9HCM3,P29992 6 +Ciliary tip 0.4789228690549621 0.7647361747223481 0.4444286605808991 1.0 0.7331014201949869 11 Q6PHR2,A0AVF1,Q7Z4L5,Q92845 4 +Endoplasmic reticulum tubular network 0.4529019302244312 0.7507900355614788 0.4527790271823781 1.0 0.7364671256293903 14 Q8NHH9,Q6NUK4,Q12797,Q9H6H4,Q9H2C2,P50402,Q9NP72,Q9NQC3 8 +Immunological synapse 0.441176819241401 0.7284344346389063 0.466347690628603 1.0 0.7479468196992778 15 P10644,O15400,Q13740,Q96L92 4 +Ragulator complex 0.7268331990330543 0.7259901445243988 0.4678448123495649 1.0 0.748164395554579 2 Q9Y2Q5 1 +Ruffle 0.356330192819224 0.7091789727664145 0.478213420422509 1.0 0.7546575484108443 68 P06756,P53365,P29317,P51790,P31751,O00592,P00533,Q06481,P05556 9 +Synaptic membrane 0.3703640732246558 0.6893508873749156 0.4906024818647783 1.0 0.7628827086865164 57 Q9BTU6,P51790,O75787,Q92542,Q14168,Q06787,Q14118,O14936,Q9Y4F1,Q9BQT9,Q15375,O14786,P05556 13 +Cytoplasmic side of membrane 0.3764632360867324 0.6803882128533886 0.4962586824834889 1.0 0.7669492579055329 47 Q96CP6,Q9NR28,P08754,P09471,Q15334,Q9H1P3,Q14344,Q9Y4F1,Q12959,P04899,P29992,P63096,P07947,P17900,Q9H0H5,P62273 16 +Sin3 type complex 0.5186567239185224 0.6759384048151471 0.4990797529833854 1.0 0.7669492579055329 6 Q9H0E3 1 +Nuclear pore outer ring 0.4861447403820238 0.6748148799503338 0.4997933854214469 1.0 0.7669492579055329 8 Q8NFH4,Q96EE3,Q8WUM0,P57740,Q12769,Q8NFH3,Q9BW27 7 +Presynaptic cytosol 0.5681753479923273 0.6555939160504154 0.5120854410887978 1.0 0.7776782732085455 4 P56545 1 +Vesicle membrane 0.5892130258496908 0.6416920183129291 0.5210731726905864 1.0 0.7865689087435587 312 Q9BXS4,Q9Y287,Q5KU26,P13473,P07602,P19021,Q9UIQ6,Q8IV08,P55899,P51790,O00462,P10253,Q92673,Q06481,P11717,Q14108,P98164,P01130,Q9NPF0,P04439,Q9NUM4,Q9NQX7,P02786,Q9Y6X5,P11279,O43493,Q7L0J3,P42892,O43752,P27105,P10321,Q08431,Q92542,Q6YHK3,Q07954,Q92581,O15118,Q99523,P42785,Q8NDZ4,P01889,O00461,Q15904,P16870,Q8WTV0,P48960,Q9NYA4,Q8IUH4,Q99805,Q9H7F0,P24390,O15260,Q86Y82,Q08722,Q9NV96,Q15043,O60245,P20645,Q8N511,Q9BRG1,Q9UNK0,O43760,Q93050,P30519,Q7Z3C6,P00533,O15400,Q9Y487,Q9H223,Q9UEU0,P35613,P06756,P11233,O95772,Q96J02,P51809,Q9NQ11,O75787,Q04656,Q9H3E2,Q14254,P05556,Q92783,Q4KMQ2,Q8N4V1,Q9Y3E7,Q9NQZ7,Q9H4M9,O15127,Q86YV9 90 +Cluster of actin based cell projections 0.3715235915297634 0.635337277857225 0.5252084659022862 1.0 0.7899616696631768 38 Q00013,O00429,Q96QD8,Q04656,Q14344,P41440,Q14728,P98164,Q9Y6M7 9 +Caspase complex 0.5060500134444702 0.6243036820037186 0.532428166295867 1.0 0.7939876285233644 6 Q96S52,Q9H490,Q969N2,O43292,P17655 5 +Cation transporting atpase complex 0.6883396023643146 0.6233280753982876 0.533068951903064 1.0 0.7939876285233644 3 P54709,P05026 2 +Sodium potassium exchanging atpase complex 0.6883396023643146 0.6233280753982876 0.533068951903064 1.0 0.7939876285233644 3 P54709,P05026 2 +Stereocilium bundle 0.4794312167563459 0.6068286299897656 0.5439646460024272 1.0 0.7991330726658818 7 Q9Y6M7 1 +Costamere 0.4708361471309448 0.6062486930429292 0.5443496229475975 1.0 0.7991330726658818 8 Q14118 1 +Cilium 0.3758746205304446 0.6007294807299813 0.5480201800683107 1.0 0.8019594673292636 104 O14965,Q13501,P22694,P05067,Q92973,P35613,Q9H4M9,P33176,A6NIH7,P10644,O60266,P17612,O95721,P29992,A0AVF1,Q8WWQ0,O14936,Q04721,P41208,P17252,Q7Z4L5,Q9HCM3,Q9H3S7,Q6PHR2,P05026 25 +Cell body membrane 0.6783987103707627 0.5908782177697034 0.554602021717215 1.0 0.805180502303508 3 P20020,P55011 2 +Desmosome 0.4747795068259185 0.5869360730884527 0.5572466415434554 1.0 0.8077439488618857 7 Q14574 1 +Neuronal dense core vesicle 0.6759806555615203 0.5830743317021341 0.5598432623588487 1.0 0.8080956093098588 3 O00255,Q96RL7 2 +Extrinsic component of membrane 0.3343511923854954 0.5726226153941001 0.5669002437234278 1.0 0.8103150623006812 73 P19022,P51149,Q15334,Q9H1P3,Q14344,P04062,P63096,P07947,Q8N3F8,P04899,O60716,Q8NI60,P29992,Q96CP6,P08754,P09471,Q5MNZ6,Q9Y4F1,O00459,P35222,Q9H0H5,Q08431,Q06787,A4D1P6,Q8TDY2 25 +Ribbon synapse 0.5452255063352085 0.5721992280976004 0.5671870103867722 1.0 0.8103150623006812 4 P56545,P16615 2 +Endoplasmic reticulum exit site 0.4011432182815867 0.5687240080837564 0.5695434524223215 1.0 0.8114890430637418 18 Q15436,Q96PC5,P04439,Q8WUM4,Q9Y3A6,Q92734,Q9NR31,O15027 8 +Gpi anchor transamidase complex 0.505913978494628 0.565151898463611 0.5719704509410644 1.0 0.8136855176700282 5 O43292,Q9H490,Q969N2,Q96S52 4 +Postsynaptic cytosol 0.4905826538042321 0.5620917774305871 0.5740534903084629 1.0 0.8143193720862827 6 Q14118 1 +Nadh dehydrogenase complex 0.3812941878449485 0.5507521967339937 0.5818035578359204 1.0 0.8225807225403244 23 O43676,P51970,O96000,Q9Y6M9 4 +Intraciliary transport particle 0.6631417129344676 0.5422604730192571 0.5876390812352121 1.0 0.827466902513382 3 Q7Z4L5 1 +Rna polymerase ii transcription repressor complex 0.6733816814397175 0.540487174384525 0.5888611036384677 1.0 0.827466902513382 2 P35222 1 +Distal axon 0.3356053436061298 0.5018688860329635 0.6157597529176944 1.0 0.8471305582804808 69 P17301,Q92859,P51790,P51114,Q06787,O94898,P51116,P78310,P05067,Q13641 10 +Extrinsic component of endoplasmic reticulum membrane 0.6543110394842826 0.4796215781724281 0.6314965000043082 1.0 0.8609045528423748 2 Q15006 1 +Lsm1 7 pat1 complex 0.5181402848696558 0.4784510002633718 0.6323292417503841 1.0 0.8609045528423748 4 Q9UK45,P62310,Q9Y4Y9 3 +Cell cortex region 0.4019052709403951 0.4424475414283749 0.6581653830081737 1.0 0.8806108915593233 13 P09496,P63096,O60716,P35222,P56545 5 +Intrinsic component of mitochondrial membrane 0.3471648471520918 0.4306763708390956 0.6667037022233757 1.0 0.8854056392243963 52 Q9H9P8,P50336,Q8IWA4,Q96NB2,Q15388,Q9NVH1,Q9NWR8,Q9BUB7,O14925,Q9GZY8,Q13505,O75880,O95140,Q9Y2R0,Q9NX63,Q99595,P17152,Q9UG56,Q9Y3D6,Q5XKP0 20 +Brush border 0.3461516707290546 0.3976572616479332 0.6908828451045883 1.0 0.9104251896405148 33 O00429,Q96QD8,Q04656,Q14344,P41440,Q14728,P98164 7 +Transporter complex 0.335635253257868 0.3968375621775434 0.6914872495855051 1.0 0.9104251896405148 62 Q8IWT6,P17252,Q9NWR8,Q9Y6M9,P51970,O75306,Q4KMQ2,O43676,O14678,Q9C0H2,Q9NV96,O96000,P17612,P0DP25,P51798,P05026,Q86WC4,Q9H813 18 +Spindle midzone 0.3546467385680114 0.37011173022453 0.7112992423050992 1.0 0.924761652639732 23 O14965,Q15058,O43663,Q9H0H5,P05067,Q15555,Q14247 7 +Rna polymerase iii transcription regulator complex 0.4758898120218958 0.3451644256568303 0.7299707613662711 1.0 0.9343219076540432 4 Q12789 1 +Transcription factor tfiiic complex 0.4758898120218958 0.3451644256568303 0.7299707613662711 1.0 0.9343219076540432 4 Q12789 1 +Postsynaptic membrane 0.3372701813126975 0.3387853348795197 0.7347714497290811 1.0 0.9391585011140828 40 P51790,O75787,Q14168,Q15375,Q14118,Q9Y4F1,Q06787,Q9BQT9,O14786 9 +Intrinsic component of peroxisomal membrane 0.4264650665847429 0.3233173716901495 0.7464548992040885 1.0 0.9471968577198312 6 Q9Y5Y5 1 +Micos complex 0.4354931711233573 0.3190710939067491 0.749672602649865 1.0 0.948076499620396 5 Q5XKP0,Q9NX63 2 +Chromocenter 0.4250913016487435 0.3186370464404869 0.7500017575887137 1.0 0.948076499620396 6 Q06787 1 +Pml body 0.3325236221641315 0.2771743976496506 0.7816461974722708 1.0 0.9707200749689416 32 Q13501 1 +Neuron to neuron synapse 0.3093946051529482 0.2654954161924833 0.790627840548821 1.0 0.9765954105703852 72 P51991,Q9BY67,P19022,Q9UQB8,Q04656,Q13614,Q14168,O43164,P51114,Q12959,Q06787,Q14012,P55795,Q9BQT9,O60716,Q96PE3,P51116,Q15375 18 +Photoreceptor outer segment 0.3766236770103436 0.2227891056759597 0.8236996473415141 1.0 1.0 8 P35613,P29992 2 +Scf ubiquitin ligase complex 0.3742574451592431 0.2144370976684383 0.8302062146731553 1.0 1.0 8 Q6PIJ6,Q96K76 2 +Paranode region of axon 0.5342465753424548 0.1868290390969726 0.8517946778723504 1.0 1.0 2 Q8IXJ6 1 +Potassium channel complex 0.5098935016380828 0.1669915347924776 0.8673767096567435 1.0 1.0 3 P0DP25 1 +Chitosome 0.5091601650447811 0.165803372566666 0.8683116919376246 1.0 1.0 3 Q04656 1 +Phosphatidylinositol 3 kinase complex 0.3972050524052768 0.1534957478428113 0.8780073433036417 1.0 1.0 4 O00459,O00443,Q08AM6 3 +Dense core granule 0.395861327600099 0.1509678196009787 0.8800011011435815 1.0 1.0 4 Q8TDJ6,O00255,Q96RL7 3 +Lateral plasma membrane 0.3205155225191238 0.1509356355238599 0.8800264894138299 1.0 1.0 26 O14641,Q86VI3,P33527,Q12959,Q5T2T1,P55011,Q8TAA9,P35222,P05026 9 +Mitochondrial crista 0.4962385814078354 0.145901961172428 0.8839987833671259 1.0 1.0 3 O60313,Q9BUB7 2 +Box h aca telomerase rnp complex 0.3915223644742551 0.1429849571664359 0.8863020615567054 1.0 1.0 4 Q9NPE3 1 +Aryl hydrocarbon receptor complex 0.484018264840183 0.117891532153071 0.9061536028210586 1.0 1.0 2 O00170 1 +Golgi apparatus 0.5840561029689953 0.106246012386299 0.9153871649118436 1.0 1.0 393 Q9BXS4,O14773,P07711,Q9Y287,P06280,P05067,P19021,O75503,Q8IV08,P16278,P50897,P53634,P51790,Q8IZA0,Q92673,Q9BQT9,P11717,Q14108,P98164,P01130,Q92896,P04439,Q15392,Q9NQX7,Q8NBN3,A2RU67,Q16739,O43493,Q8N6G5,O43752,P10321,Q92542,Q8NBJ4,O60512,Q8NBZ7,Q07954,O15118,O43852,Q99523,O43505,Q8NDZ4,P01889,O00461,P80303,Q9NX62,P04062,Q14118,Q7LGA3,P16870,Q5VW38,O95456,Q8IUH4,Q99805,P24390,O60266,O15260,Q6AZY7,Q9P2W9,Q8WVQ1,Q86Y82,Q8NCH0,Q9H2C2,Q9NV96,Q04721,Q9Y282,Q5SRI9,Q8TCG2,Q92859,Q9P2E5,P20645,Q9UNK0,Q9NPR9,Q9H9S5,Q93050,Q7Z3C6,Q8TB61,Q9BTU6,Q8IY95,P00533,Q9UEU0,P35613,P53365,Q6ZRP7,O95249,P51809,P11166,Q9UNK9,P13591,Q99640,Q04656,Q68CQ7,O94766,P46934,Q92544,P33908,Q86SF2,O43823,Q8N4V1,P07947,Q9NQZ7,Q9BVK6,Q16706,O15127,Q92520,O95721,Q9Y2G5,Q4J6C6,P08754,Q7Z3D4,Q8WWQ0,P98194,O43164,Q6P1K2,Q9H0U4,Q9UQB8,Q10472 116 +Mpp7 dlg1 lin7 complex 0.4629921206075719 0.1035258090723128 0.9175456668644012 1.0 1.0 3 Q12959 1 +Torc1 complex 0.4618484685652767 0.1022872249829579 0.9185286951074724 1.0 1.0 3 P42345,Q96Q15 2 +Tor complex 0.4618484685652767 0.1022872249829579 0.9185286951074724 1.0 1.0 3 P42345,Q96Q15 2 +Site of polarized growth 0.3077019485338123 0.0934873014860582 0.9255164374587546 1.0 1.0 59 Q92859,Q9BTU6,P51114,O94898,P51116,P78310,P05067 7 +Scar complex 0.3447163215918208 0.0900892440625811 0.9282162964578478 1.0 1.0 6 Q9Y6W5,Q8IZP0,Q9Y2A7,Q96F07,Q9H7N4 5 +Mitochondrial alpha ketoglutarate dehydrogenase complex 0.3560870733673764 0.0880277303836783 0.92985463603035 1.0 1.0 4 O14874,P11182,P09622 3 +Nuclear pore central transport channel 0.3528621338349874 0.0839150832620236 0.9331239471506418 1.0 1.0 4 Q7Z3B4,Q8NFH5,P37198 3 +Clathrin complex 0.4292237442922344 0.075247760388425 0.940017584744698 1.0 1.0 2 P09496 1 +Catenin complex 0.3302315300057859 0.0745377664805471 0.9405824914267564 1.0 1.0 7 O60716,P19022 2 +Nuclear inner membrane 0.3080528927180302 0.0726513993117819 0.942083524017423 1.0 1.0 24 Q9H1E5,P62995,Q13185,Q14728,O75844,P50402,Q8IXM6 7 +Inclusion body 0.3057077307589111 0.0715930365058297 0.942925781919362 1.0 1.0 31 Q13501,Q14145,O14641,Q9UL15 4 +Trapp complex 0.4258463191832279 0.0701601277711362 0.9440662095148288 1.0 1.0 3 Q9Y2L5,Q9Y296 2 +Paranodal junction 0.4184797206553876 0.0700671383690743 0.9441402221790408 1.0 1.0 2 Q8IXJ6 1 +Parallel fiber to purkinje cell synapse 0.4184797206553776 0.0700671383690696 0.9441402221790448 1.0 1.0 2 P23634 1 +Sperm annulus 0.3996776792908911 0.0629463954300481 0.9498091898600484 1.0 1.0 2 Q15019 1 +Phosphatidylinositol 3 kinase complex class iii 0.396991673381684 0.0621084195424749 0.9504764921196952 1.0 1.0 2 Q08AM6 1 +Septin cytoskeleton 0.3997850617947254 0.0543280602535536 0.956673793711276 1.0 1.0 3 Q15019,Q9UHD8 2 +Wnt signalosome 0.3416599516518923 0.0520179861828777 0.9585143619138196 1.0 1.0 2 P35222 1 +Compact myelin 0.329841525651362 0.0510917256240529 0.9592524293786672 1.0 1.0 2 Q8IXJ6 1 +Basal dendrite 0.3204405049691121 0.0505399670596959 0.9596921009752206 1.0 1.0 2 O15498 1 +Cell leading edge 0.3681472503848759 0.039170948345079 0.968754095715294 1.0 1.0 139 Q16625,O75955,Q14118,P00533,P05067,Q14517,P06756,P53365,P51790,Q14168,Q06481,P51809,P29317,O75787,Q04656,Q14254,P05556,P31751,O00592,P41440 20 +Trna methyltransferase complex 0.3473938742611366 0.0365752849428151 0.9708236500996368 1.0 1.0 3 Q7L0Y3,Q9UJA5 2 +Trans golgi network transport vesicle membrane 0.3077956989247254 0.0353969202556013 0.9717632404546696 1.0 1.0 5 P09497,O43747,P09496,Q00610 4 +Extrinsic component of postsynaptic specialization membrane 0.3164965072541538 0.0319741421712612 0.9744926719088234 1.0 1.0 3 Q14160,P52292 2 +Mmxd complex 0.2775389575496926 0.0294548637450361 0.9765018168206048 1.0 1.0 3 Q96T76,P18074 2 +Respiratory chain complex iii 0.31325625168056 0.0291200276628983 0.9767688628051878 1.0 1.0 6 P08574,P31930,O14949,P22695,P14927 5 +Prefoldin complex 0.3108389647185047 0.0251478571223672 0.9799370277735592 1.0 1.0 6 O15212 1 +Filopodium tip 0.3079612694997387 0.0237259949278924 0.9810711708856992 1.0 1.0 7 Q9H4L5,Q7L576,Q9Y4I1,P61086,Q8IZP0,Q06787 6 +Calcium channel complex 0.3045026537417611 0.0084265989964301 0.9932766263291708 1.0 1.0 9 P17612,P0DP25,Q9NWR8 3 +Kinetochore microtubule 0.3018563357546356 0.0053737769989874 0.995712366935326 1.0 1.0 8 O75122,Q8WUX9,O43264,Q9UQN3,Q9Y3E7,Q9NZZ3,P50748 7 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6e5ee5995aaa043266b34e908c1f33b5c4a7ca66 --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atg1 ulk1 kinase complex", "Atp binding cassette abc transporter complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Axonemal microtubule", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc complex", "Blood microparticle", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Calyx of held", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Cbm complex", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body fiber", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition fiber", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytoskeleton of presynaptic active zone", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystroglycan complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fanconi anaemia nuclear complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fhf complex", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner acrosomal membrane", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle a", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mks complex", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Mon1 ccz1 complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class i", "Phosphatidylinositol 3 kinase complex class ia", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Phosphorylase kinase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Serine type endopeptidase complex", "Serine type peptidase complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Striated muscle thin filament", "Sumo ligase complex", "Super elongation complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquinone biosynthesis complex", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACE2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADCY3", "ADD1", "ADD2", "ADD3", "ADGRE5", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALG9", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID4B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL6IP6", "ARL8B", "ARMC1", "ARMC10", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG7", "ATG9A", "ATL2", "ATL3", "ATM", "ATP11C", "ATP13A1", "ATP13A2", "ATP13A3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATRN", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BANP", "BAP1", "BAP18", "BARD1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT1", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCL10", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BEND3", "BET1", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C10orf88", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C17orf75", "C19orf70", "C1QBP", "C1orf35", "C21orf59", "C2CD5", "C2orf49", "C3orf58", "CAB39", "CABIN1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAMSAP3", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARS2", "CASK", "CASP8", "CASP8AP2", "CAST", "CBL", "CBX1", "CBX2", "CBX3", "CBX4", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC22", "CCDC47", "CCDC86", "CCNB1", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD109", "CD276", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK7", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPI", "CENPU", "CENPV", "CEP170", "CEP250", "CEP290", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHM", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CIT", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLK2", "CLK3", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COCH", "COG3", "COG4", "COG7", "COG8", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPE", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRAT", "CREG1", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTBS", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX35", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DMD", "DMXL2", "DNA2", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC8", "DNAJC9", "DNASE2", "DNM1", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4ENIF1", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "ENPP1", "ENPP4", "ENTPD7", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM105A", "FAM162A", "FAM208A", "FAM234B", "FAM3C", "FAM49B", "FAM83D", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FAT1", "FBL", "FBXO21", "FBXO22", "FBXO38", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FNBP1", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FREM2", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GGCX", "GGH", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GIT1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLE1", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRAMD1A", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOOK2", "HP1BP3", "HPF1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "ISCA2", "ISCU", "ISOC1", "IST1", "ISY1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPK1", "ITPRIP", "ITSN2", "IVD", "JAGN1", "JAK1", "JCAD", "JUP", "KANK2", "KARS", "KAT5", "KAT7", "KATNA1", "KCTD10", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA1549", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFAP3", "KIFBP", "KIFC1", "KIN", "KIRREL1", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDB1", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN2", "LMAN2L", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRIG1", "LRIG2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSG1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYSMD3", "M6PR", "MACF1", "MAD2L1BP", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4", "MAP4K4", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBLAC2", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED27", "MEN1", "MEPCE", "MESD", "METTL13", "METTL15", "METTL17", "METTL7B", "MFAP1", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD8", "MGA", "MGAT2", "MGRN1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMADHC", "MMGT1", "MMS19", "MMS22L", "MOB4", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRC2", "MRE11", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTFR1", "MTFR1L", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MTX3", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA4", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NEO1", "NEPRO", "NES", "NEU1", "NF1", "NF2", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NID1", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME4", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C3A", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT19", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "OAT", "OBSL1", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC1", "ORC2", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSTM1", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAK1IP1", "PAK2", "PALLD", "PAM", "PAN2", "PANX1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PECR", "PEF1", "PELP1", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF2", "PHF5A", "PHF6", "PHF8", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4K2B", "PI4KA", "PI4KB", "PIAS1", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGO", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLEKHA7", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA3", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNMA1", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "PODXL", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL2", "PPIL3", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP5C", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKACB", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPN1", "PTPN13", "PTPN23", "PTPRF", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSER1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB31", "RAB32", "RAB33B", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1CC1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMI1", "RMND1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF20", "RNF213", "RNF219", "RNF31", "RNF40", "RNMT", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP2", "SCAMP3", "SCAMP4", "SCAP", "SCARA3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SCYL1", "SCYL2", "SDAD1", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SELENOI", "SENP3", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGSH", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHCBP1", "SHMT2", "SHPRH", "SHTN1", "SIAE", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A6", "SLFN11", "SLIRP", "SLK", "SLTM", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG6", "SMN1*", "SMNDC1", "SMPD4", "SMPDL3B", "SMU1", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX25", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORL1", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPHK2", "SPOUT1", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6L", "TAF9B", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TCTN3", "TDRD7", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX2", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "TGOLN2", "TGS1", "THADA", "THAP11", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TKT", "TLE3", "TLN1", "TM7SF2", "TM9SF2", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM11", "TMEM115", "TMEM126B", "TMEM14C", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM206", "TMEM214", "TMEM230", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMEM98", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM32", "TRIO", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT112", "TRMT5", "TRMT6", "TRMU", "TROVE2", "TRPC4AP", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTF2", "TTI2", "TTK", "TTLL12", "TTLL4", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAC1", "UBAC2", "UBAP1", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGCG", "UGGT1", "UHRF1", "ULK3", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "USE1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP28", "USP32", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAC14", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VLDLR", "VMP1", "VPS11", "VPS13A", "VPS13C", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "VTI1B", "WAPL", "WASF2", "WASHC3", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR70", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WLS", "WRN", "WRNIP1", "WTAP", "WWP2", "XAB2", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H14", "ZC3H18", "ZCCHC11", "ZCCHC8", "ZCCHC9", 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"COA3", "COCH", "COLEC12", "COMT", "COQ8A", "COX15", "CPE", "CREG1", "CRTAP", "CSGALNACT2", "CTBP2", "CTBS", "CTNNB1", "CTNND1", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CTTN", "CXADR", "CYC1", "CYFIP1", "CYFIP2", "DAG1", "DAGLB", "DBT", "DDX3X", "DHCR24", "DHCR7", "DIABLO", "DIP2B", "DLD", "DLG1", "DMXL2", "DNAJC10", "DNAJC11", "DNAJC3", "DNASE2", "DNM1", "DNM1L", "DOCK1", "DOLPP1", "DSC3", "DSG2", "DVL2", "ECE1", "EGFR", "EHD1", "EHD4", "EMC2", "EMD", "ENPP1", "ENPP4", "ENTPD7", "EPDR1", "EPHA2", "EPHA7", "ERCC2", "ERGIC3", "F11R", "FAM234B", "FAM3C", "FARP1", "FAT1", "FBXO38", "FCGRT", "FIS1", "FKBP14", "FKBP7", "FKRP", "FLOT1", "FLOT2", "FMR1", "FREM2", "FTL", "FUCA1", "FUCA2", "FXR1", "FXR2", "GAA", "GALNS", "GALNT1", "GALNT2", "GALNT7", "GBA", "GGH", "GLA", "GLB1", "GLG1", "GLT8D1", "GM2A", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNS", "GOLIM4", "GOLM1", "GOSR1", "GPAA1", "GPR107", "GPR108", "GRAMD1A", "GRB2", "GTF3C1", "GUSB", "HEXA", "HEXB", "HGS", "HLA-A", 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sha256:027f979295953e063f1d0762680e9e1f072e60ba02613a87bf00db0f5ca86fb8 +size 143236 diff --git a/msigdb_gomf/consensus.joblib b/msigdb_gomf/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..01c722a7f2ace69248d4088bb2c2645a9156c390 --- /dev/null +++ b/msigdb_gomf/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:af863761dabf98e71d75d19ed8ac839c403d9b82d1f0b2520610f7d8e86d7457 +size 205218 diff --git a/msigdb_gomf/df_merge.tsv b/msigdb_gomf/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7bebf36775bba29f491a3d41eeb43a6591496268 --- /dev/null +++ b/msigdb_gomf/df_merge.tsv @@ -0,0 +1,92 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Molecular transducer activity 34 53 3.943239476001418 8.038831114376421e-05 10.91747572815534 33.40533980582524 1.343848990749489 0.2329582295822712 4.7124072380860955 5.830391636254363 1.6098335072319665 0.2956883791113679 1.485181281950898e-09 0.1323708772076377 0.0120091141738882 2.845056473344861e-09 2.7721297916798888e-08 +Hydrolase activity acting on glycosyl bonds 17 38 3.915751141669237 9.012317387879776e-05 10.133495145631068 28.40776699029126 0.6089784953463463 0.2409908190925149 3.36301188653944 3.2424277527979313 1.935823411407979 0.3010513017078077 3.811359058871488e-14 1.5287446355258344e-12 5.021108337141856e-18 4.615896615283874e-15 2.0690752139063133e-13 +Hydrolase activity hydrolyzing o glycosyl compounds 19 28 3.558030438293205 0.0003736460233703 8.830097087378642 20.84223300970874 0.5983257656540719 0.2104301479001341 3.2223833352824554 2.4557961681485057 1.9540573665272416 0.2728112677124137 5.5881484668258634e-14 1.1151864980490069e-12 8.108423809027802e-18 9.185269922408168e-15 1.64717959899266e-14 +Exogenous protein binding 16 23 3.3822849265417334 0.0007188554268364 4.509708737864078 15.157766990291265 0.7214109752050332 0.2527966464979699 2.499010078306418 1.9009100692398744 1.5211756979359785 0.2791170769282048 1.582166783446387e-09 1.0 0.0008840144918394 9.936897298788151e-07 1.0653823770076551e-11 +Exopeptidase activity 11 35 3.338482548468574 0.0008423732152071 9.74514563106796 31.84223300970874 1.193034763402526 0.2308543476384821 3.0338864063053523 1.9513159274241312 1.6646797512653713 0.2911825093455628 6.511486818361973e-08 1.1178795131295548e-05 5.535129873037549e-09 1.8190494996864507e-08 2.905428449216434e-05 +Cargo receptor activity 12 15 3.2487398023819214 0.0011591745733567 3.7063106796116503 7.95873786407767 0.9623237890522576 0.1578680760704802 1.9530058934839476 1.7914972745396005 1.6202205206532496 0.203966946010782 8.244949911521215e-14 0.0003334624710947 2.860752955016867e-12 1.85898136101663e-14 1.33202816067551e-10 +Peptide binding 14 83 3.2221444510935475 0.0012723497095781 17.133495145631066 70.30339805825243 1.21997288878307 0.3503559587509399 5.621054768990946 6.443005397350486 1.219878183292811 0.3773673755377006 1.0065994243701211e-05 0.0057124733176429 1.3533719736714705e-06 2.4715761965478645e-06 0.0002583172881567 +Anion transmembrane transporter activity 25 56 3.1823017016151613 0.0014610953018794 18.594660194174757 45.61893203883495 1.6222323024349488 0.2373683627198559 9.346785472607134 6.017202751823004 1.8117646078257517 0.3183345645365742 4.488211774895828e-08 0.1267011687502946 0.1209939299005533 1.9494418180980646e-06 5.998034002285853e-07 +Endopeptidase activity 13 74 3.069906095498935 0.0021412608379547 19.08495145631068 62.800970873786405 1.5604938505680932 0.2935756148549138 5.629332570724372 6.156865220927466 1.27979578418692 0.359984229645684 0.0054309448768746 0.0001494244895398 0.0010673811822192 0.0022666889994947 0.0147417162663287 +Serine hydrolase activity 8 22 3.055837368765053 0.002244329541732 6.934466019417476 18.83009708737864 1.2767207242593377 0.1489147276149277 2.386872767465543 1.965791668457755 1.709796217367629 0.2208345231085202 3.838249264390716e-05 8.494254101186968e-05 5.985378049573102e-06 1.6783269894967037e-05 8.060398640515672e-05 +Calcium ion binding 29 101 2.99645031210034 0.0027314274779235 21.00485436893204 81.67961165048544 0.6464856503310022 0.4940276647939897 7.408010340962093 8.52860815905726 1.2261945166831902 0.3858741960292539 1.696109512576269e-06 0.1540130058624756 0.000317107667331 8.821335373441887e-07 2.918897537068908e-05 +Growth factor binding 11 19 2.986513279253709 0.0028217858281494 4.310679611650485 12.949029126213592 -0.0488380105863232 0.5194853451197696 2.1509949209095054 2.534197950354086 1.057563900891323 0.317878019437427 1.4902946970872791e-05 1.0 0.0285769937968429 3.837942278655153e-05 0.0001032946331356 +Carbohydrate binding 15 54 2.838071073158693 0.0045387075107989 11.281553398058252 45.27669902912621 0.1331338248817691 0.6071141686502306 4.369282618080822 4.120884622804317 0.96731611422719 0.3295982480677992 0.0002969279733732 0.0002461797194024 1.5760678950066837e-06 0.0001086615195287 4.033208502948221e-05 +Collagen binding 9 14 2.771857406705202 0.0055737446628993 2.716019417475728 8.723300970873787 0.69823887636622 0.4150184287426759 1.4191600413356955 1.3333441338677146 0.9396547940704922 0.2968068810392446 0.0001551062961394 0.0100088432903632 0.0002069103237917 8.233120100309505e-05 1.1495068697305945e-06 +Secondary active transmembrane transporter activity 9 28 2.7086297741604453 0.0067561684030235 9.080097087378642 21.490291262135923 1.2627683473613005 0.2947710034053126 5.466215032972134 3.0675886156990426 1.4241587428281404 0.3340388164945335 0.0001258791810337 0.3523884632837075 0.5741114914523541 0.0012481596775334 0.009885665008765 +Snap receptor activity 12 18 2.675449123542354 0.0074629199335625 5.803398058252427 13.6626213592233 0.8920027438628428 0.3386294703372389 3.103034547770364 2.9171839264116786 1.2201519782198902 0.3219991979242683 0.0020491830728424 1.0 1.0 0.0086864012748381 3.027113983893673e-08 +Udp glycosyltransferase activity 13 25 2.6751098852303694 0.0074704760042836 5.111650485436893 16.645631067961165 0.3599735227181602 0.3819150449260511 2.50187506268716 3.5246228662547776 1.2344018614792536 0.2994506580113357 0.004074968927174 0.0521335433076176 0.005792379744814 0.0021480935661603 0.0031709677504383 +Cation transmembrane transporter activity 28 84 2.659778792780003 0.007819198727123 25.62135922330097 70.51699029126213 1.766742880952279 0.2698419237572138 12.29126021871486 8.422243011776631 2.00238274385689 0.3706372466673562 0.0015298902455213 0.6829262542482903 0.655123576832411 0.010203975961045 2.233988473439152e-06 +Amyloid beta binding 7 17 2.657067455989993 0.0078823669153975 3.5898058252427183 10.560679611650484 1.053866189591651 0.2544642672774957 2.009490338022764 1.9342863324228672 1.0942484681219342 0.2534200432416059 0.0004273875299793 0.1665759675679584 0.0004155585626268 0.0002303056568621 0.0003189699178862 +Anion channel activity 8 14 2.636488564501098 0.0083769023658188 4.20873786407767 11.21116504854369 1.03959259790327 0.2192420598609839 2.3076742714116403 2.0905640066649145 1.3937691950814175 0.2662450395835827 8.496955950432245e-05 0.0082126449787597 0.0023694947377154 4.476197901851534e-05 0.0002922281845516 +Active ion transmembrane transporter activity 19 52 2.629075320358884 0.0085617395366457 16.271844660194176 41.71116504854369 1.2957221273899948 0.3267733012969381 7.788084220174416 5.097264791179653 1.6571109350293016 0.3632481416270505 8.085360635685861e-05 0.4420266901261166 0.6821824234140106 0.0021780899236958 5.040206982776925e-05 +Glycolipid binding 3 11 2.6286148222175787 0.008573340687614 3.95873786407767 9.17233009708738 1.1300394975336625 0.1723818604496332 1.779261971800237 1.789101691327159 1.517965150696512 0.2390589148665743 0.0009463420108467 1.1619966216201592e-06 1.7352123755419733e-05 0.0006143549700213 0.0009961752813945 +Proteoglycan binding 7 8 2.619906166072528 0.0087953964313189 1.362530413625304 3.1289537712895377 0.2680687531458016 0.4279813903596159 1.1106462996140136 1.3688980509063906 1.3416152040458127 0.3356932777486967 1.5221248257749522e-07 0.0030581061915538 0.0005309775927247 6.917341646628312e-08 4.737926010639901e-07 +Inorganic molecular entity transmembrane transporter activity 37 94 2.617735226069877 0.0088515457424285 28.058252427184467 75.9635922330097 1.5031303400189615 0.2894264293069549 11.721339963426631 9.38477049228959 2.153051736566399 0.3821536813265525 0.0001051336987135 0.3353278359280591 0.2055751104444995 0.0008003980868384 2.1200484995224795e-06 +Glycosaminoglycan binding 8 20 2.6054418567768662 0.0091755845408505 4.978155339805825 17.45631067961165 0.1337124269810174 0.5629551361084434 2.38360266105164 2.069316753377374 0.9690169198659552 0.3148101721496325 0.0017964561645034 0.0402962873689797 0.0244837275894334 0.000923573561466 0.0038884735347153 +Active transmembrane transporter activity 32 85 2.6040878000259893 0.0092119154746708 26.354368932038835 73.12621359223301 1.313035419122872 0.3239574057550545 11.878456281473593 8.663537710607383 1.88741562841277 0.3851687956916088 0.0011767649799035 0.6332097195283641 0.8606155698177973 0.0098201702249896 0.0003092652778181 +Serine type exopeptidase activity 5 7 2.602356358597406 0.0092585591018219 3.783980582524272 6.997572815533981 1.020609253431403 0.1137432544246352 1.3363606860118669 0.0492066381861973 1.87035730934538 0.1990592265121372 2.9249147174479992e-08 9.130642966886304e-06 9.047098753082273e-09 1.4679347449836997e-08 9.308926617220138e-07 +Steroid binding 8 27 2.599130690340456 0.0093460183653608 8.424757281553399 21.398058252427184 1.4469817519716153 0.1523451695819165 3.035656818503787 2.066091501771892 1.85140774519605 0.2395996334984524 0.0019601597157597 0.2145132052110039 0.0803922289273931 0.0010882828125207 0.000495982234219 +Inorganic anion transmembrane transporter activity 15 26 2.587266633773823 0.0096740700668342 7.427184466019417 19.274271844660195 1.0921593405593897 0.2441056926448881 3.717191605498929 3.7816647851785734 1.4014196343960104 0.2816216967014333 9.081461175905364e-06 0.0267403422938185 0.0135419734012732 3.079730523933523e-05 0.0001637882770494 +Protein lipid complex binding 5 7 2.574173543349742 0.0100479859683606 1.3810679611650485 4.075242718446602 0.904959910455646 0.2381476109936121 0.9668941495076666 1.0318560378441015 1.279214127988033 0.237092245379572 3.003469201819414e-07 0.0015075035399645 3.74476751148508e-06 1.5190256075674532e-07 9.033677057044543e-06 +Cysteine type endopeptidase activity 4 30 2.5496499470620844 0.0107831129155053 6.643203883495145 22.70873786407767 -0.1512639295018987 0.5573451178319037 3.668466707980015 5.029777481540216 0.9075554152638888 0.3060681644864327 0.0407656399904217 0.0003697647875954 0.0045315560193572 0.0266777247012389 0.1225859328480348 +Peptide antigen binding 4 7 2.5354980796767728 0.0112287544107612 2.25 5.218446601941747 1.3488418251083294 0.2076946662826 1.4985834735457568 1.269832767279765 0.9581301458127084 0.2397273125927817 3.368893008845366e-05 0.0711332726649859 0.0003602808960722 1.934192081629664e-05 0.0005240184523993 +Scavenger receptor activity 5 7 2.532355369152701 0.0113299099663699 2.128640776699029 4.245145631067961 0.8895147156183107 0.1752904943890176 1.2029313295363038 0.9324780265795692 1.5451274177295422 0.2106852326062687 3.003469201819414e-07 0.0015075035399645 0.0001778916397324 1.5190256075674532e-07 9.033677057044543e-06 +Metal ion transmembrane transporter activity 18 35 2.523087690959428 0.0116329388208356 9.563106796116504 24.67233009708738 0.8657396859235934 0.3700615753207195 4.93288923178502 4.839352380624028 1.4450904591933955 0.3424002804304004 0.0058124833424792 1.0 1.0 0.0281363706052967 7.741044054276856e-05 +Lipoprotein particle receptor activity 5 6 2.518508034665828 0.0117853194642003 0.558252427184466 1.9611650485436891 1.168446998823525 0.1996268153441312 0.915881905289026 1.1378085741458248 1.8266476741437696 0.265806683699643 1.5365616255530653e-07 0.0526645480715484 2.515038607063009e-06 7.751339245084413e-08 4.709357290896995e-06 +Sphingolipid binding 3 8 2.4988415093561342 0.0124600022553713 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 0.0011910371662417 0.0034296220851759 0.0126574737404708 0.0007750266814789 0.0096830476876922 +Ceramide binding 3 6 2.495248378356953 0.0125868990333024 2.8228155339805827 5.048543689320389 1.42330045764979 0.1242195400491618 1.17628831869178 0.9309003969609838 1.481980135982154 0.2133994029014766 0.0003096916980164 0.0017760204843955 0.0066572828402184 0.0001991597833083 0.0027426851014433 +Antigen binding 4 9 2.4910629423355024 0.0127361554949272 2.504854368932039 6.936893203883495 1.1926555941065955 0.2669458193807861 1.6287691845260013 1.3674077446215156 0.9067202373946956 0.2605304200525402 0.0003159858167221 0.1070183553885475 0.0013262573806951 0.0001850299811141 0.0042587077964903 +Sodium ion transmembrane transporter activity 7 10 2.4717041643716087 0.0134470743129502 3.033980582524272 6.733009708737864 0.6330876716410718 0.3951789521880264 1.773267150762252 1.4834287460359985 1.0827590126064015 0.3202441368223486 0.0042473390043545 1.0 1.0 0.0153023562212604 0.0027819419936207 +Sterol binding 6 22 2.464317445074152 0.0137274472213879 5.495145631067961 16.27912621359223 1.1610523788441311 0.1592175050218891 2.159304933149918 1.9111962434971217 1.7231989277496158 0.231586711794193 0.0026567983669971 0.1624541869963563 0.0466281418945222 0.0016056440309417 0.0014723052630428 +Heparin binding 5 13 2.462003497828336 0.0138163319310948 3.4344660194174756 11.91504854368932 0.417671776261347 0.5410412518682232 1.977562601051691 1.5719219414069263 0.9122022863658426 0.3149614964035694 0.0064222178805025 0.1948770046367652 0.0666692325567911 0.0039562767661884 0.0185344065780108 +Extracellular matrix binding 5 7 2.457521210103388 0.0139899549349502 2.1262135922330097 4.490291262135922 -0.1059374832306895 0.5792352498707123 1.334236348624189 1.2472894544280944 0.8854509277358328 0.3082832623553992 0.0260894037169127 1.0 0.2070995190727305 0.0193169154759243 0.0007997701188881 +Monosaccharide binding 7 32 2.454311122434081 0.0141154795941458 6.529126213592233 27.652912621359224 0.1441354722061465 0.6253240236055831 3.188514919494202 2.1774252770244877 0.8383687523157859 0.3062926587902204 0.0012495075938431 6.575020599903326e-05 6.670129789082706e-05 0.000686888501954 0.0012669874007928 +Low density lipoprotein particle receptor activity 4 5 2.446020876089521 0.014444263668619 0.9836734693877552 1.6448979591836734 -0.5593575058371455 0.2177029191255377 0.866460531450471 1.026398741884836 2.0898844560946817 0.275956017068443 3.160792089650874e-06 0.0479914252810258 1.612359251599596e-06 1.7923085924657402e-06 5.383729574080712e-05 +Lipid transporter activity 13 29 2.445743756606835 0.0144553696882365 6.546116504854369 19.805825242718445 0.7389006587243017 0.301332987440896 3.074370954053146 3.741159812966952 1.4134673193588587 0.2984913911167897 0.0177709564038919 0.0546342218360011 0.1690424872723929 0.0380983070787084 0.0038503971554757 +Serine type carboxypeptidase activity 4 5 2.4336785830702894 0.0149462605123942 3.0558252427184467 4.997572815533981 1.0019911760482532 0.1105835516254352 1.1231414198895626 0.0492066381861973 1.8086551291944464 0.1930654928989846 1.402816173698501e-08 0.0002334823336694 3.9836639152197847e-08 7.85578396891505e-09 2.618746245991888e-07 +Organic anion transmembrane transporter activity 15 35 2.42020082149769 0.0155119378349579 12.951456310679612 30.182038834951456 1.56101282472555 0.2452312368187786 6.880574373146614 3.5222410835885483 1.575669523214114 0.314839840161206 0.002066270879254 1.0 1.0 0.0543296939149059 0.0025572246433095 +Cholesterol binding 6 18 2.40227411512938 0.0162934939086187 5.25 13.29126213592233 1.1679703080780182 0.1357521674166823 1.9454015982929531 1.7674569958716484 1.7544522374432017 0.2116991383290636 0.0011462155823435 0.1373006943976843 0.0334071197556988 0.0006827439557333 0.0004618757702046 +Carboxypeptidase activity 5 14 2.3934193582146004 0.0166921502619605 3.941747572815534 11.944174757281552 0.6619369631013473 0.2217581052142344 1.5253536449314826 0.7722681563953175 1.6063564059694095 0.2594343390807456 3.3253048315786296e-05 0.0060718409625537 7.357256485958134e-05 1.734109635655837e-05 0.0007997701188881 +Hexosyltransferase activity 16 44 2.385036397826826 0.0170774316350899 9.633495145631068 33.87864077669903 0.7349501031127185 0.3949358882560483 4.261380470236419 4.330948695045228 1.2646745007039175 0.3422146027467064 0.0121079316044836 0.107450887051756 0.0239832744272861 0.0062659657814626 0.0034065449773006 +Gated channel activity 7 15 2.331690622111483 0.0197169725186647 4.317961165048544 13.019417475728156 0.8697524591818097 0.2583579989367679 2.2914716766946497 2.0107989163575497 1.3733766112751231 0.2762671399351702 0.0054811628079177 0.0348230103466341 0.0198486300115185 0.0031264397563519 0.0079827384799552 +Antiporter activity 4 12 2.3259309765746496 0.020022233200138 4.621359223300971 10.405339805825244 1.056576117278179 0.2813324268221227 2.679901841610502 1.304685592846984 1.2558310293487471 0.3063102364368053 0.0037988331286127 0.1747599807978781 0.3143397790261298 0.0140312853386763 0.0387405426335318 +Vitamin transmembrane transporter activity 5 9 2.306487354374047 0.0210834159211061 2.7766990291262137 6.252427184466019 1.4438342367310928 0.182339474606115 1.52603324115363 1.3650879028699858 1.0282691527982806 0.2346378729908682 0.0137899394557154 1.0 1.0 0.0757571260003459 0.0017273216459823 +Alcohol binding 6 22 2.2969786899259046 0.021619985420219 5.70873786407767 16.094660194174757 1.0972550148478282 0.1642412137618775 2.3364194162363723 2.1334758164294443 1.72577974721897 0.2306417307890987 0.0109923043020199 0.2183837422916212 0.0832345551471358 0.0068683859678987 0.0098371476265694 +Laminin binding 4 6 2.2960688939457934 0.021671942521773 1.9368932038834952 3.9271844660194177 -0.0786584912021696 0.5959740026174113 1.1599707304025848 0.827053980318478 0.8817229896867529 0.3119744678247755 0.008459922663953 1.0 0.1432798584585485 0.0061570039439817 0.000732082482726 +Tetrapyrrole binding 8 19 2.237658163333079 0.0252433554727296 7.402912621359223 16.83252427184466 2.0044897428967667 0.1259264696495541 2.9589081005845346 2.0417036568087963 1.3464702305086589 0.2177422235164347 0.0032350682163615 0.2336798458054532 0.0949012099695084 0.0094868932073139 0.0010356106420026 +Hexosaminidase activity 3 5 2.232532320861329 0.0255798015284143 2.5194174757281553 4.973300970873787 0.3568105957806153 0.2227497456156347 1.091499214132507 0.3065083294438748 1.6445593916296413 0.2548912926080147 5.946720119657204e-05 6.332255610474929e-08 9.745982190989103e-07 3.788095303003865e-05 0.0005644670723367 +Cysteine type peptidase activity 5 55 2.231198798999766 0.0256679635028456 12.109223300970871 44.08495145631068 -0.1451192974466758 0.596001868152635 6.000017182713323 7.277780171243459 0.8950128681796422 0.3160523160059556 0.1832326873597222 0.0049315444833474 0.0114556487875666 0.1257883710531202 0.5288975428316326 +Serine type endopeptidase inhibitor activity 2 8 2.2046915416811026 0.0274757470766482 1.924757281553398 5.526699029126213 0.0879544181827763 0.5160396848581311 1.5490895194100334 1.1133635632531 1.045243956687472 0.329000705737948 0.0137899394557154 0.0892490045576324 0.014058804472369 0.0101015401572799 0.0615084186624239 +Sulfuric ester hydrolase activity 3 5 2.2028407141068804 0.0276059774233301 1.0631067961165048 2.5097087378640777 0.2563507017783891 0.3793182931823819 0.7542102268363194 0.6590688581829386 1.365543872017702 0.3079518911843922 0.0001491979893058 0.0012601973854463 0.0047533286028597 9.549361773523036e-05 0.0013678067399173 +Palmitoyl protein hydrolase activity 1 7 2.195559824749122 0.0281234644766519 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0402937008043179 0.0015075035399645 0.0056684159955205 0.032628233248221 0.1121927202905578 +Mannose binding 3 7 2.194277648153096 0.0282154553305038 2.487864077669903 6.235436893203883 0.6101269701833572 0.2582145467051042 1.3337836904766196 0.6757998162537485 1.36750331402198 0.2531492078603038 0.0009932781732133 0.000647621121882 4.656667989155393e-05 0.0007102815399137 0.0003260526470588 +G protein beta gamma subunit complex binding 6 7 2.183361977986942 0.0290091636568157 1.8592233009708736 5.075242718446602 0.1156832975314603 0.5066419156307818 1.5717738969541342 1.3022268788503704 1.0034827017508308 0.3094562156647272 1.0 1.0 1.0 1.0 0.0048470794580564 +Voltage gated anion channel activity 5 7 2.179572157877384 0.0292891904938179 2.854368932038835 6.25 1.127126362633441 0.1649553590552043 1.5417035527207152 0.9966570336472054 1.4583344406160936 0.2334940994157564 9.70048072649134e-05 0.0479914252810258 0.0921025797166938 6.194004931981708e-05 5.383729574080712e-05 +Apolipoprotein binding 2 5 2.170421306436575 0.0299749441619048 0.6893203883495146 3.366504854368932 0.652778548294341 0.3954646193515305 0.8621392023028659 0.5738174141081086 0.9902706983692476 0.2741767944189784 0.0014601836592373 0.0432957136582515 0.0832836732680532 0.0010464818333657 0.0076273123324074 +Chaperone binding 14 47 2.169094761922812 0.0300754902978301 9.58252427184466 41.577669902912625 0.0857966897601569 0.6702931427923858 4.408782655318593 3.2622117709628737 0.7810306428207174 0.3113373258659207 0.0802825225964291 0.3426841548479852 0.0089732445190698 0.0543296939149059 0.0214635815193847 +Palmitoyltransferase activity 2 6 2.167093249135565 0.0302277445787506 1.8786407766990292 5.084951456310679 0.875863834441912 0.3421870647647222 1.2306088543936362 0.6827036113457149 1.018188317250868 0.2997914787323893 0.0923316485580286 1.0 1.0 0.0757571260003459 0.0615084186624239 +Amino acid transmembrane transporter activity 5 12 2.166506955299814 0.0302724689445321 4.325242718446602 10.521844660194176 0.9562493229862624 0.2921494362491497 2.574340086864074 1.34633933573134 1.106576767449958 0.2884960270895668 0.0042473390043545 1.0 1.0 0.0025916473916576 0.0118494727859131 +Transmembrane receptor protein tyrosine kinase activity 4 7 2.151801897807372 0.0314129603233084 1.5266990291262137 3.3155339805825244 -0.2707749466539293 0.4571736705144678 1.068873727499588 1.1245069928642772 1.1904003252126492 0.3288677925887929 0.0037988331286127 1.0 0.3143397790261298 0.0140312853386763 0.0387405426335318 +Transmembrane receptor protein kinase activity 4 7 2.151801897807372 0.0314129603233084 1.5266990291262137 3.405339805825242 -0.2400877987855226 0.4551118965545555 1.0891190778455828 1.2141042609169368 1.2003769712866084 0.3284266388044581 0.0092791543097421 1.0 0.371655018795122 0.0280832529132891 0.0813065502215209 +Tap binding 2 5 2.147897111335695 0.0317219299208475 1.8592233009708736 3.895631067961165 0.8127354819395453 0.3477955376218754 1.070154411615344 1.0456940556701602 1.051123567423606 0.2887299843781864 0.0006334572131993 1.0 0.0653907127050202 0.0004519701832281 0.0034179138545613 +Protein tyrosine kinase activity 6 21 2.135372434924204 0.032730600444023 5.012135922330097 13.58980582524272 -0.3853098962361698 0.5582723721465958 3.318431653917148 2.9459850844218423 0.8131778391228522 0.3077327579735024 0.0350197019128561 1.0 0.5823300890010559 0.1723284412806655 0.145563506517747 +Mannosidase activity 4 5 2.1321817481009537 0.0329919083148977 1.186700767263427 2.734015345268542 -0.0164720249367898 0.379181316989432 0.8808430685898523 1.1221298664168404 1.498553635853625 0.3139607509780454 0.0045876876261238 0.0619434524836269 0.0066572828402184 0.0033170374819039 0.0002434795729679 +Clathrin heavy chain binding 2 6 2.1095785081531524 0.0348946771539797 0.9563106796116504 4.172330097087379 0.3682910274765735 0.3434838107739949 1.107360186700709 1.195424695125345 1.3132806864166615 0.2873136636013117 0.0009932781732133 1.0 0.0743799864466655 0.0007102815399137 0.0052730305790767 +Retromer complex binding 2 5 2.096246430592854 0.0360603360967588 1.7864077669902914 4.62378640776699 0.1266826261911074 0.4322045282144987 1.2199831722291083 0.628387698804986 1.1917576639553151 0.3183570223820515 0.0009932781732133 1.0 0.0743799864466655 0.0007102815399137 0.0052730305790767 +Phosphatidylserine binding 3 11 2.0636621272201867 0.0390497625936987 2.029126213592233 10.060679611650484 0.6615116985008255 0.3340719518205703 1.5854698894895154 0.9597266622759548 1.1646704221215245 0.2873190862432436 0.0064450358458905 1.0 0.0293903981750984 0.0042924995678 0.0443313868612348 +Cytokine binding 4 9 2.0586812697155352 0.0395247816704789 1.9344660194174756 5.871359223300971 -0.200397297123543 0.5251679609353982 1.2971501460018051 1.17846992171863 0.8909842648469317 0.2852942278930233 0.087927706130726 0.1747599807978781 0.3143397790261298 0.0671599559498881 0.0387405426335318 +Ion transmembrane transporter activity 45 120 2.0542046680679253 0.0399558867990366 37.34466019417476 101.497572815534 2.0154097423383375 0.2561362875319209 17.172953606300336 11.579295798802024 2.277787478419462 0.3756175790939143 1.1197014193818633e-05 0.4519882054911213 0.3480510906614062 0.0005101889066339 1.089980166430786e-07 +Organic acid transmembrane transporter activity 6 26 2.053479231354478 0.0400261219686772 8.592233009708737 21.276699029126213 1.5973629153049684 0.1905568538747131 4.4420473133518055 2.549726956007885 1.3213968531498468 0.2647933566957936 0.0023355066279001 1.0 1.0 0.0058282629537454 0.016498993555687 +Transition metal ion transmembrane transporter activity 4 6 2.0335630744990127 0.041995668027241 2.2597087378640777 4.444174757281553 1.267846808399692 0.205487024774009 1.5353529408674886 1.9618423203326616 1.2931295194130703 0.2516620757205828 0.136684668071892 1.0 1.0 0.4439075633632242 0.0051689545539866 +G protein alpha subunit binding 1 5 2.0292186280405744 0.0424360270447339 1.2815533980582523 3.96116504854369 1.1518090627532231 0.2356662931606298 0.7653601947652959 0.7780025469432862 1.0915303524696884 0.2503004448344019 0.0682786800017594 1.0 0.1432798584585485 0.0557098434243155 0.1801322612125274 +Voltage gated channel activity 6 11 2.022627167070456 0.0431116010932524 3.2257281553398056 10.116504854368932 0.8578192560085278 0.2690365421745596 1.8168622808181427 1.411127559025233 1.234834479111217 0.2694186191218866 0.0128645943328501 0.1541506060207377 0.2802926639431586 0.0086864012748381 0.0053005354814706 +Signaling receptor regulator activity 4 20 2.019903440220376 0.0433934043832131 4.072815533980583 17.339805825242717 0.7311308082630681 0.4520633016494398 2.421493327854957 2.496807274147909 0.9157780911218903 0.317372323464707 0.1353775558521509 0.3024216363859021 0.1554832015057707 0.2579811764447431 0.2789251234894486 +Peptidase activity 20 130 2.018113287215256 0.0435794641678148 29.021844660194176 113.626213592233 1.2572335980018865 0.3731282983707893 8.334453494010912 9.805689463637474 1.5136028692995414 0.3922229485757941 4.317187188374557e-05 1.0227198624600388e-05 6.871636595207527e-07 7.591467828762224e-06 0.0040436947721797 +Coreceptor activity 4 5 2.0133048046347 0.0440825732254133 1.5825242718446602 2.983009708737864 -0.1219149568441634 0.543561837621635 1.0242143268256676 0.8574078511459474 0.9958037451472654 0.3174759955577475 0.1008235479946778 1.0 1.0 0.3867116248199588 0.0142025885279179 +Galactosyltransferase activity 1 5 2.013170600670827 0.0440966849557051 1.4004854368932038 4.014563106796117 0.4835514024572315 0.4297894898723106 1.1026445515529784 1.0725079733100582 1.0886375545888918 0.3129067636178667 0.0682786800017594 1.0 1.0 0.0557098434243155 0.1801322612125274 +Wide pore channel activity 3 5 2.010541441184055 0.0443739147343065 2.157766990291262 4.266990291262136 1.156945559067054 0.1661436788367006 1.073449599559222 0.4792567768515825 1.4176309163665306 0.2377490100494037 0.0183539828864478 1.0 1.0 0.0147480216610697 0.0052730305790767 +Snare binding 15 36 2.002931293065619 0.0451846636781527 8.696601941747574 30.067961165048544 0.0392228827891846 0.6710878435029795 4.003358796945836 3.8142862160957023 0.7596376972140344 0.3087820264570225 0.1605036780263974 1.0 1.0 0.2908433959862969 0.0012638246218667 +Solute sodium symporter activity 3 5 1.9955054348644865 0.045987781989119 1.3135802469135802 3.096296296296296 0.4666631088686246 0.4397000633844223 0.933829641377906 1.0485079869167702 1.1446814583555502 0.320733039344894 0.0100699756610546 1.0 1.0 0.0621585272883563 0.046330877355434 +Atpase binding 7 28 1.994866390070573 0.0460574540812235 7.101941747572815 27.883495145631063 0.4324538219085727 0.5124445450748666 3.2760229435557595 2.201283698181438 0.9496598819558206 0.3233068270066163 0.0989797926787676 1.0 0.4672829604777532 0.4675997956478902 0.012770185546351 +L amino acid transmembrane transporter activity 3 9 1.9771234699183424 0.0480276754496646 3.628640776699029 8.201456310679612 0.919975936290114 0.2876791162304417 2.2759730869054327 1.0290432051153906 1.15482978403653 0.2925518180165951 0.0073200005110444 1.0 1.0 0.0048864602536943 0.0495301536946375 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b7b3fb6533a383cf1aebad9065b692a8192f3997 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 1452, + "title": "Average number of proteins per term", + "value": 18.27754820936639 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..174662d9aa0fadad538faef2f8d9577d1602427a --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7cb322e8122cb2a5d84178b971adcb8b55d833aa --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,455 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Molecular transducer activity 0.7781156656395625 3.943239476001418 8.038831114376421e-05 0.1101732691502314 0.0654294242360079 53 Q99523,P15260,O15173,Q5KU26,P00533,Q15629,Q8WTV0,P51805,P48960,P17301,P98155,P06756,Q9NRA0,Q9Y6I9,Q92673,P11717,Q14108,Q9UBG0,P29317,O75787,Q08722,P10586,O14786,P05556,Q04721,Q92859,P20645,Q15375,Q9UNN8,Q92692,O75882,Q07954,O15118,Q9Y6N7 34 +Hydrolase activity acting on glycosyl bonds 0.8232725901532675 3.915751141669237 9.012317387879776e-05 0.1226635699628833 0.0654294242360079 38 Q92485,O00754,P16278,P54802,P06865,O00462,Q9BTY2,P10253,P07686,P13051,P04066,P06280,P08236,P17900,Q01459,O75503,Q99519 17 +Hydrolase activity hydrolyzing o glycosyl compounds 0.8330366087253017 3.558030438293205 0.0003736460233703 0.4187855057045319 0.1808446753112309 28 P33908,Q04446,Q8IW92,Q9BTY2,P04062,P06280,P17900,P16278,P54802,P06865,O00462,P10253,P07686,P08236,Q01459,P04066,Q99519,O00754,Q5SRI9 19 +Exogenous protein binding 0.8368285897283915 3.3822849265417334 0.0007188554268364 0.6480103201507548 0.2181367137879339 23 P17301,P35613,P06756,P01130,P13591,P29317,P02786,Q14118,P00533,P78310,P11279,Q8WTV0,Q14108,O15118,Q9Y624,Q92692 16 +Exopeptidase activity 0.7360185413434888 3.338482548468574 0.0008423732152071 0.7058429181214817 0.2181367137879339 35 O14773,Q9UIQ6,P42785,P53634,Q9HB40,Q9H3G5,P02786,Q92820,O75976,P10619,P16870 11 +Cargo receptor activity 0.9223193243934906 3.2487398023819214 0.0011591745733567 0.814388175458293 0.2181367137879339 15 P01130,Q9NPF0,Q8WTV0,Q07954,Q5KU26,P02786,Q92673,Q08380,O15260,Q14108,P98164,P98155 12 +Peptide binding 0.6032707954986704 3.2221444510935475 0.0012723497095781 0.8425469686051537 0.2181367137879339 83 P42892,O14773,Q9UIQ6,P01130,P04439,Q8WTV0,Q15392,P10321,P55899,Q9NQX7,P01889,Q9Y287,Q92673,Q07954 14 +Anion transmembrane transporter activity 0.6600374737548725 3.1823017016151613 0.0014610953018794 0.8803353167814826 0.2181367137879339 56 Q8TB61,Q96QD8,Q4KMQ2,Q9C0H2,P55011,Q96NB2,Q8IWT6,P33527,P51790,P11166,P51798,Q9H813,Q9H2D1,Q15043,P21796,Q99808,P45880,Q9BXP2,Q9Y619,P08195,P30825,P41440,Q9Y277,Q92581,Q9Y6M7 25 +Endopeptidase activity 0.5714061108715414 3.069906095498935 0.0021412608379547 0.9555079254041275 0.2181367137879339 74 Q9BXS4,O14773,Q99538,P07711,P42892,O43847,P07858,P53634,Q16740,Q92542,O75844,Q2T9J0,Q9UBX1 13 +Serine hydrolase activity 0.7891100169323164 3.055837368765053 0.002244329541732 0.961704728435514 0.2181367137879339 22 O14773,P42785,P53634,Q9HB40,Q9H3G5,O75976,Q2T9J0,P10619 8 +Calcium ion binding 0.6069596660455359 2.99645031210034 0.0027314274779235 0.9811540840051648 0.2181367137879339 101 P33908,P43304,Q9UM22,P80303,Q14118,Q9H223,P19021,P48960,Q14257,Q14517,P98155,Q9H4M9,P15289,Q9NWM8,Q9BQT9,P98164,Q15293,P01130,Q9NPF0,Q8WVQ1,Q14574,P14543,O75071,O60245,Q04721,Q14126,O94813,Q07954,O43852 29 +Growth factor binding 0.8116637896424164 2.9865132792537095 0.0028217858281494 0.983477375860442 0.2181367137879339 19 Q99523,P06756,Q92896,P29317,Q15375,P00533,Q6YHK3,O00560,P11717,O14786,P98164 11 +Carbohydrate binding 0.6211725598142367 2.838071073158693 0.0045387075107989 0.9986466932205668 0.2181367137879339 54 Q9UBG0,Q86SF2,P35613,O00754,Q04446,Q32P28,O15460,P10253,Q5KU26,O00462,P08236,P11717,O75882,P19021,O75503 15 +Collagen binding 0.8396010618208019 2.771857406705202 0.0055737446628993 0.999701193928028 0.2181367137879339 14 Q9UBG0,P17301,P07711,O75718,O43405,Q32P28,P07858,P14543,Q92791 9 +Secondary active transmembrane transporter activity 0.6873375151753689 2.7086297741604453 0.0067561684030235 0.9999468953148968 0.2181367137879339 28 Q9H2J7,P51790,Q96QD8,Q9BXP2,P08195,P41440,Q92581,P51798,Q15043 9 +Snap receptor activity 0.7618729115767856 2.675449123542354 0.0074629199335625 0.9999811084673934 0.2181367137879339 18 O43752,Q9P2W9,Q86Y82,O00161,O95249,Q9UNK0,O15400,O95721,P51809,Q5SQN1,Q9NZ43,Q9UEU0 12 +Udp glycosyltransferase activity 0.6986977476953142 2.6751098852303694 0.0074704760042836 0.9999813161435374 0.2181367137879339 25 Q86SF2,O43505,P06865,Q9P2E5,Q10472,O60512,P07686,Q8N6G5,Q16739,O94766,Q9Y673,Q10469,Q10471 13 +Cation transmembrane transporter activity 0.5438926114603088 2.659778792780003 0.007819198727123 0.99998878318813 0.2181367137879339 84 Q93050,Q8TEL6,Q96QD8,Q4KMQ2,Q8N4V1,Q9Y487,Q7KZN9,Q96NB2,P06756,Q8IUH4,P51790,Q9H7F0,Q9NQ11,Q96RD7,Q04656,P98194,Q13423,Q6P4Q7,Q15043,Q9H2J7,Q9BXP2,Q9Y619,P08195,P30825,Q9HD20,Q92581,P05026,Q9Y6M7 28 +Amyloid beta binding 0.7678174525148371 2.657067455989993 0.0078823669153975 0.9999897736499248 0.2181367137879339 17 P17301,P01130,Q07954,Q9NQX7,Q9Y287,Q92673,Q8WTV0 7 +Anion channel activity 0.8108455308494021 2.636488564501098 0.0083769023658188 0.9999950419288486 0.2181367137879339 14 P21796,P45880,P51790,Q4KMQ2,Q9C0H2,Q9Y277,P51798,Q9H813 8 +Active ion transmembrane transporter activity 0.5995149976655508 2.6290753203588837 0.0085617395366457 0.9999962176679288 0.2181367137879339 52 Q96QD8,Q7KZN9,P55011,Q9H7F0,P33527,P51790,P51798,Q9NQ11,Q04656,P98194,Q15043,Q9H2J7,Q9BXP2,P08195,P41440,Q9HD20,Q92581,P05026,Q9Y6M7 19 +Glycolipid binding 0.8656334892901694 2.6286148222175787 0.008573340687614 0.9999962813885516 0.2181367137879339 11 Q9UM22,O14773,P07602 3 +Proteoglycan binding 0.9244013989776696 2.6199061660725276 0.0087953964313189 0.9999973138718588 0.2181367137879339 8 P07711,P07858,P14543,O94813,P10586,O00560,Q07954 7 +Inorganic molecular entity transmembrane transporter activity 0.5552158505252238 2.617735226069877 0.0088515457424285 0.99999752597536 0.2181367137879339 94 Q93050,Q8TEL6,Q96QD8,Q4KMQ2,Q8N4V1,Q9C0H2,Q9Y487,P55011,Q7KZN9,Q8IWT6,P06756,Q8IUH4,P33527,P51790,Q9H7F0,Q9Y666,P51798,Q9NQ11,Q9H813,Q96RD7,Q9NWR8,Q04656,P98194,Q13423,Q6P4Q7,Q15043,P21796,P08574,P45880,Q9H2J7,Q9Y277,Q9BXP2,P08195,Q9HD20,Q92581,P05026,Q9Y6M7 37 +Glycosaminoglycan binding 0.7288999075577207 2.6054418567768662 0.0091755845408505 0.9999984611084278 0.2181367137879339 20 P51688,Q07021,O94813,P10586,Q06481,P15586,O14786,P05067 8 +Active transmembrane transporter activity 0.5396447670721177 2.6040878000259893 0.0092119154746708 0.9999985408991507 0.2181367137879339 85 O75306,Q96QD8,Q7KZN9,P55011,P16615,P08183,Q9UBX3,P33527,P51790,Q9H7F0,P51970,Q9Y666,P51798,Q9NQ11,Q03519,O43676,Q04656,Q15758,P98194,O96000,Q15043,Q9Y6M9,P08574,Q9H2J7,O14678,Q9BXP2,P08195,P41440,Q9HD20,Q92581,P05026,Q9Y6M7 32 +Serine type exopeptidase activity 0.9402681744674276 2.602356358597406 0.0092585591018219 0.9999986373074732 0.2181367137879339 7 O14773,Q9HB40,Q9H3G5,O75976,P10619 5 +Steroid binding 0.6752964377668276 2.599130690340456 0.0093460183653608 0.9999988012500644 0.2181367137879339 27 P21796,Q9BXW6,P45880,P61916,O95772,P04062,Q14108,O15118 8 +Inorganic anion transmembrane transporter activity 0.6787735734128505 2.587266633773823 0.0096740700668342 0.999999258904072 0.2181367137879339 26 Q8IWT6,P21796,Q9Y6M7,P45880,P33527,P51790,Q4KMQ2,Q9BXP2,Q9Y666,Q9C0H2,P55011,Q9Y277,P51798,Q15043,Q9H813 15 +Protein lipid complex binding 0.9331528001570418 2.574173543349742 0.0100479859683606 0.9999995717114925 0.2181367137879339 7 P01130,Q9BQE5,Q5KU26,Q92673,P98155 5 +Cysteine type endopeptidase activity 0.6500772558822864 2.5496499470620844 0.0107831129155053 0.9999998543570532 0.2181367137879339 30 Q99538,P07711,P53634,P07858 4 +Peptide antigen binding 0.9234293858080752 2.5354980796767728 0.0112287544107612 0.9999999242918576 0.2181367137879339 7 P10321,P55899,P04439,Q15392 4 +Scavenger receptor activity 0.9226413516673672 2.532355369152701 0.0113299099663699 0.9999999347430688 0.2181367137879339 7 Q07954,Q5KU26,Q08380,Q8WTV0,Q14108 5 +Metal ion transmembrane transporter activity 0.6135252924087439 2.523087690959428 0.0116329388208356 0.9999999581863062 0.2181367137879339 35 Q96RD7,Q8TEL6,P06756,Q8IUH4,Q9H2J7,Q96QD8,Q04656,P98194,Q9BXP2,Q8N4V1,P08195,P55011,Q6P4Q7,Q9HD20,Q92581,Q15043,P05026,Q9Y6M7 18 +Lipoprotein particle receptor activity 0.9602043560096764 2.5185080346658277 0.0117853194642003 0.9999999665736076 0.2181367137879339 6 P01130,Q92673,Q07954,P98164,P98155 5 +Sphingolipid binding 0.8946266714115619 2.4988415093561342 0.0124600022553713 0.9999999876001452 0.2181367137879339 8 Q9UM22,P21796,P07602 3 +Ceramide binding 0.9541874636871176 2.495248378356953 0.0125868990333024 0.9999999897108096 0.2181367137879339 6 Q9UM22,P21796,P07602 3 +Antigen binding 0.8731759041711397 2.4910629423355024 0.0127361554949272 0.999999991738598 0.2181367137879339 9 P10321,P55899,P04439,Q15392 4 +Sodium ion transmembrane transporter activity 0.849456755328912 2.4717041643716087 0.0134470743129502 0.9999999970972836 0.2181367137879339 10 Q9H2J7,Q96QD8,P08195,Q6P4Q7,Q92581,P05026,Q9Y6M7 7 +Sterol binding 0.6833799091605043 2.4643174450741516 0.0137274472213879 0.9999999980788232 0.2181367137879339 22 P21796,Q9BXW6,P45880,P61916,Q14108,O15118 6 +Heparin binding 0.7915985711533788 2.4620034978283356 0.0138163319310948 0.9999999983144784 0.2181367137879339 13 O94813,P10586,Q06481,O14786,P05067 5 +Extracellular matrix binding 0.9039680401571608 2.457521210103388 0.0139899549349502 0.9999999986947168 0.2181367137879339 7 P17301,P06756,P14543,O94813,Q14118 5 +Monosaccharide binding 0.6233436038404874 2.454311122434081 0.0141154795941458 0.9999999989150212 0.2181367137879339 32 P35613,Q32P28,O00462,Q5KU26,P11717,P19021,O75503 7 +Low density lipoprotein particle receptor activity 0.9685483870967756 2.446020876089521 0.014444263668619 0.9999999993315208 0.2181367137879339 5 P01130,Q92673,P98164,P98155 4 +Lipid transporter activity 0.639796245786213 2.445743756606835 0.0144553696882365 0.9999999993423696 0.2181367137879339 29 Q96CP6,Q9BXW6,Q7Z3C6,P61916,P33527,Q4KMQ2,O14678,Q9H1P3,Q9H2C2,Q9NV96,P11166,P17900,O15118 13 +Serine type carboxypeptidase activity 0.9653225806451636 2.4336785830702894 0.0149462605123942 0.999999999680986 0.2181367137879339 5 O75976,Q9HB40,P10619,Q9H3G5 4 +Organic anion transmembrane transporter activity 0.5989262968173491 2.42020082149769 0.0155119378349579 0.9999999998614586 0.2181367137879339 35 Q8IWT6,Q99808,Q9H2D1,Q9Y6M7,Q9UBX3,Q8TB61,P33527,Q96QD8,Q9Y619,P08195,P30825,P11166,P41440,Q14728,Q96NB2 15 +Cholesterol binding 0.7104135455906329 2.40227411512938 0.0162934939086187 0.999999999956271 0.2181367137879339 18 P21796,Q9BXW6,P45880,P61916,Q14108,O15118 6 +Carboxypeptidase activity 0.7604628106693077 2.3934193582146004 0.0166921502619605 0.9999999999757248 0.2181367137879339 14 P42785,Q9HB40,Q9H3G5,O75976,P10619 5 +Hexosyltransferase activity 0.5836308176286433 2.385036397826826 0.0170774316350899 0.9999999999862584 0.2181367137879339 44 Q2TAA5,Q86SF2,Q04446,O43505,P06865,Q9P2E5,Q10472,O60512,P04062,P07686,Q8N6G5,Q16739,O94766,Q9Y673,Q10469,Q9Y2G5 16 +Gated channel activity 0.7310734556494212 2.331690622111483 0.0197169725186647 0.9999999999997232 0.2305439983511127 15 P21796,P06756,P45880,P51790,Q9C0H2,P51798,Q9H813 7 +Antiporter activity 0.7787182631999179 2.3259309765746496 0.020022233200138 0.9999999999998238 0.2307324016396863 12 Q92581,P51798,P51790,P08195 4 +Vitamin transmembrane transporter activity 0.8297100996146682 2.306487354374047 0.0210834159211061 0.9999999999999636 0.2309999363511911 9 Q9H2D1,O14678,P04062,P41440,P11166 5 +Alcohol binding 0.6548869641479935 2.2969786899259046 0.021619985420219 0.9999999999999836 0.2309999363511911 22 P21796,Q9BXW6,P45880,P61916,Q14108,O15118 6 +Laminin binding 0.9033453629354667 2.2960688939457934 0.021671942521773 0.9999999999999848 0.2309999363511911 6 P17301,Q14118,P14543,O94813 4 +Tetrapyrrole binding 0.6719347763415758 2.237658163333079 0.0252433554727296 1.0 0.2395643931137475 19 Q9NPF0,P30519,Q8WUJ1,O43169,O15173,Q16850,Q7KZN9,P53701 8 +Hexosaminidase activity 0.9133849417037012 2.232532320861329 0.0255798015284143 1.0 0.2404508581040763 5 P06865,P17900,P54802 3 +Cysteine type peptidase activity 0.5429445611434179 2.231198798999766 0.0256679635028456 1.0 0.2404508581040763 55 Q99538,P07711,P53634,P07858,Q92820 5 +Low density lipoprotein particle binding 0.9596882558451996 2.210343736117918 0.0270813154200879 1.0 0.2457629374372982 4 Q5KU26,P01130,Q92673 3 +Serine type endopeptidase inhibitor activity 0.824140967826314 2.2046915416811026 0.0274757470766482 1.0 0.2459133694397262 8 P05067,Q06481 2 +Sulfuric ester hydrolase activity 0.9058165967597416 2.2028407141068804 0.0276059774233301 1.0 0.2459133694397262 5 P34059,P15289,P15586 3 +Palmitoyl protein hydrolase activity 0.8399413848805009 2.195559824749122 0.0281234644766519 1.0 0.2482960069084338 7 Q9UMR5 1 +Mannose binding 0.8396329631305915 2.194277648153096 0.0282154553305038 1.0 0.2482960069084338 7 O75503,O00462,P11717 3 +G protein beta gamma subunit complex binding 0.837009144701458 2.183361977986942 0.0290091636568157 1.0 0.2522233870041702 7 P08754,P09471,Q14344,P04899,P63096,P29992 6 +Voltage gated anion channel activity 0.8360989713134441 2.179572157877384 0.0292891904938179 1.0 0.253142289267998 7 P21796,P45880,P51790,Q4KMQ2,P51798 5 +Apolipoprotein binding 0.8975807875578581 2.170421306436575 0.0299749441619048 1.0 0.2540787566905244 5 Q07954,P98155 2 +Chaperone binding 0.5509595279291125 2.169094761922812 0.0300754902978301 1.0 0.2540787566905244 47 Q9NZJ4,Q8IXB1,Q9UL15,P53634,P01889,Q9UDY4,Q9NQP4,Q04656,Q96KC8,P02786,P55011,Q14108,O15212,P98164 14 +Palmitoyltransferase activity 0.8710517179897261 2.167093249135565 0.0302277445787506 1.0 0.2540787566905244 6 Q8IUH4,P23786 2 +Amino acid transmembrane transporter activity 0.7449108582702701 2.166506955299814 0.0302724689445321 1.0 0.2540787566905244 12 Q9H2J7,Q96QD8,Q9Y619,P08195,P30825 5 +Transmembrane receptor protein tyrosine kinase activity 0.8294419826070532 2.151801897807372 0.0314129603233084 1.0 0.2591569226672945 7 Q15375,P29317,O14786,P11717 4 +Transmembrane receptor protein kinase activity 0.8294419826070532 2.151801897807372 0.0314129603233084 1.0 0.2591569226672945 7 Q15375,P29317,O14786,P11717 4 +Tap binding 0.8918756482096868 2.147897111335695 0.0317219299208475 1.0 0.2602273573167832 5 P10321,P04439 2 +Protein tyrosine kinase activity 0.6369092433298684 2.1353724349242036 0.032730600444023 1.0 0.2655018538811259 21 P29317,P23458,Q15375,P00533,P11717,O14786 6 +Mannosidase activity 0.8879032258064598 2.1321817481009537 0.0329919083148977 1.0 0.2661347270735084 5 P33908,O00754,Q5SRI9,O00462 4 +Clathrin heavy chain binding 0.85680277957804 2.1095785081531524 0.0348946771539797 1.0 0.273876060689614 6 P01130,Q07954 2 +Retromer complex binding 0.8788444877787256 2.096246430592854 0.0360603360967588 1.0 0.2815032688843755 5 Q99523,P11717 2 +Phosphatidylserine binding 0.7406387840089387 2.0636621272201867 0.0390497625936987 1.0 0.2920498949674342 11 Q08431,Q14108,Q06481 3 +Cytokine binding 0.772899548348734 2.0586812697155352 0.0395247816704789 1.0 0.2920498949674342 9 O14786,P06756,P15260,Q6YHK3 4 +Ion transmembrane transporter activity 0.5350974454059664 2.0542046680679253 0.0399558867990366 1.0 0.2920498949674342 120 Q93050,Q8TEL6,Q8TB61,Q96QD8,Q4KMQ2,Q8N4V1,Q9C0H2,Q9Y487,P55011,Q7KZN9,Q96NB2,Q8IWT6,P06756,Q8IUH4,P33527,P51790,Q9H7F0,Q9Y666,P11166,P51798,Q9NQ11,Q9H813,Q96RD7,Q9H2D1,Q9NWR8,Q04656,P98194,Q13423,Q6P4Q7,Q15043,P21796,Q99808,P08574,P45880,Q9H2J7,Q9Y277,Q9BXP2,Q9Y619,P08195,P30825,P41440,Q9HD20,Q92581,P05026,Q9Y6M7 45 +Organic acid transmembrane transporter activity 0.5938165133654247 2.053479231354478 0.0400261219686772 1.0 0.2920498949674342 26 Q9H2D1,Q9H2J7,Q96QD8,Q9Y619,P08195,P30825 6 +Transition metal ion transmembrane transporter activity 0.8381087797012273 2.0335630744990127 0.041995668027241 1.0 0.2960599420351147 6 Q9HD20,Q8N4V1,Q15043,Q04656 4 +Insulin like growth factor binding 0.91404429945292 2.0334904788220824 0.0420029945311526 1.0 0.2960599420351147 4 P98164,P11717 2 +G protein alpha subunit binding 0.8620379084954577 2.0292186280405744 0.0424360270447339 1.0 0.2968798336719236 5 P11717 1 +Volume sensitive anion channel activity 0.9113030278647578 2.0227752891464994 0.0430963204742584 1.0 0.2980859275590595 4 Q9C0H2 1 +Voltage gated channel activity 0.7318976528321046 2.0226271670704556 0.0431116010932524 1.0 0.2980859275590595 11 P21796,P06756,P45880,P51790,Q4KMQ2,P51798 6 +Signaling receptor regulator activity 0.6258181124972975 2.019903440220376 0.0433934043832131 1.0 0.2984782168474868 20 P05067,Q9NPF0,P14174,Q15375 4 +Peptidase activity 0.5451371326018509 2.018113287215256 0.0435794641678148 1.0 0.2984782168474868 130 Q9BXS4,O14773,P07711,P42785,P07858,Q9HB40,O75976,P16870,Q9UBX1,Q99538,Q9UIQ6,P53634,Q92820,P10619,Q9H3G5,O75844,P02786,Q2T9J0,P42892,Q92542 20 +Coreceptor activity 0.8580645161290384 2.0133048046347 0.0440825732254133 1.0 0.2991980680172146 5 P05556,P06756,Q92692,O14786 4 +Galactosyltransferase activity 0.8580310348717959 2.013170600670827 0.0440966849557051 1.0 0.2991980680172146 5 O60512 1 +Wide pore channel activity 0.8573752019736323 2.010541441184055 0.0443739147343065 1.0 0.2996787171823863 5 Q96RD7,P21796,P45880 3 +Snare binding 0.5410708879580416 2.002931293065619 0.0451846636781527 1.0 0.3023416205561189 36 Q9BVK6,Q99747,Q5SQN1,O43752,Q86Y82,Q13190,O00161,Q9UNK0,Q9H270,O15400,Q8WU76,O95721,P51809,Q15833,Q9UEU0 15 +Solute sodium symporter activity 0.8536278410855058 1.9955054348644865 0.045987781989119 1.0 0.3053672297987971 5 Q9H2J7,Q96QD8,Q9Y6M7 3 +Atpase binding 0.576323873629468 1.994866390070573 0.0460574540812235 1.0 0.3053672297987971 28 Q93050,P11233,Q9NUM4,Q16740,Q92542,P00533,Q9Y487 7 +L amino acid transmembrane transporter activity 0.7545682112374108 1.9771234699183424 0.0480276754496646 1.0 0.3104820077782807 9 Q9Y619,Q96QD8,P30825 3 +Dipeptidyl peptidase activity 0.8983561944112493 1.9720293475831563 0.0486062563926921 1.0 0.3104820077782807 4 P53634 1 +Sterol transporter activity 0.6875809933870987 1.9553266730318408 0.0505445248772298 1.0 0.3149813309945824 13 P61916,Q9H2C2,O15118 3 +G protein coupled receptor binding 0.5455489939224518 1.9503448555363967 0.051135029732614 1.0 0.317299415263913 33 O14641,P11233,P08754,P09471,Q07021,P23458,Q14344,Q96J02,P04899,O00560,P63096,P0DP25,P46934 13 +Integrin binding 0.5878654922065326 1.942775064928589 0.0520433419328452 1.0 0.3195111281560092 23 P17301,P06756,Q08431,P78310,Q9Y624,P05556,Q9Y2I1 7 +Beta n acetylhexosaminidase activity 0.8906254550625841 1.941620725460942 0.0521830319827647 1.0 0.3195111281560092 4 P06865,P17900 2 +Acetylgalactosaminyltransferase activity 0.8153235724937505 1.9400660876005216 0.0523716587473348 1.0 0.3195111281560092 6 Q86SF2,Q9P2E5,Q10472,Q8N6G5 4 +Abc type transporter activity 0.683149457652564 1.933024837279382 0.0532331381960788 1.0 0.3207241355216039 13 P08183,Q03519,Q9H7F0,P33527,O14678,Q9HD20,Q9NQ11 7 +Phosphoric diester hydrolase activity 0.6335380095460812 1.899155791511804 0.0575439953727818 1.0 0.336298290779194 16 Q92485,Q8IV08 2 +Ionotropic glutamate receptor binding 0.8051899127388609 1.8981905298316424 0.057670987881556 1.0 0.336298290779194 6 Q13501,P41440 2 +Glutamate receptor binding 0.7351439120039622 1.8898598117434269 0.0587767116480397 1.0 0.3400150809281025 9 Q13501,P41440 2 +Glycosyltransferase activity 0.4901616326291295 1.8740974330429312 0.0609169970781928 1.0 0.3496105919270199 60 Q2TAA5,Q86SF2,Q10471,Q04446,O43505,P06865,Q9P2E5,Q10472,O60512,P04062,P07686,Q8N6G5,Q16739,Q68CQ7,O94766,Q9Y673,Q10469,Q9Y2G5 18 +Syntaxin binding 0.5753245177150125 1.8629491472461948 0.062469421189212 1.0 0.3548257267420001 23 Q9BVK6,Q99747,O43752,O00161,Q9UNK0,Q9H270,Q8WU76,O15400,O95721,Q5SQN1,Q15833 11 +Protease binding 0.5224206406799405 1.8588560407744943 0.0630475464872148 1.0 0.3548257267420001 35 P01130,P06756,Q96RD7,P14174,O75955,P07602,P41440,Q2T9J0,P05556 9 +Modified amino acid binding 0.5821557643094689 1.8533827790199704 0.0638275138560779 1.0 0.3570317761543513 22 Q8WTV0,Q08431,Q14108,Q06481 4 +Ephrin receptor binding 0.7424680745047672 1.8503792952885232 0.0642589010335177 1.0 0.3570317761543513 8 Q15375 1 +Protein transporter activity 0.6246651255353024 1.8498450998431772 0.0643358785110042 1.0 0.3570317761543513 16 Q9NS69,Q9HD20,P98164,Q99595 4 +Solute cation antiporter activity 0.8668309022440807 1.847539569713225 0.0646689787387013 1.0 0.3570317761543513 4 Q92581,P51790 2 +Phospholipid binding 0.4984642743736441 1.8282894949163913 0.0675061155944403 1.0 0.3610166240594423 110 O14773,Q9UM22,Q9NWW5,P07602,Q8WTV0,Q9Y2I1,Q9BXW6,P50897,P53365,Q06481,Q14108,Q9NQ11,Q9H3E2,Q8NCC3,P21796,P45880,Q08431,Q9UKS6,Q92783,O00560 20 +Phosphatidylcholine binding 0.7371483247649069 1.8268070904855735 0.0677287794242575 1.0 0.3610166240594423 8 P21796,Q14108 2 +Fad binding 0.6748368200987488 1.825821905656146 0.0678770925401017 1.0 0.3610166240594423 12 O95831,O00116,Q8NB78,Q15392 4 +Porin activity 0.8590988006541573 1.816815865669004 0.0692453126408971 1.0 0.364034656146884 4 P21796 1 +Hormone binding 0.7026808402535076 1.8105410839621976 0.0702119192277732 1.0 0.3655473265200001 10 P42892,P00533,P98164 3 +Acetylglucosaminyltransferase activity 0.7489932623280289 1.809114553819262 0.0704332085010353 1.0 0.3655473265200001 7 P06865,P07686 2 +Atpase coupled transmembrane transporter activity 0.5404189612917685 1.8087411940648128 0.0704912199900826 1.0 0.3655473265200001 30 P08183,Q15388,Q03519,Q9H7F0,P33527,Q04656,P98194,O14678,Q9NUT2,P05026,Q9HD20,P51798,Q9NQ11,P16615 14 +Metalloexopeptidase activity 0.5747403741890679 1.8068017998003627 0.0707931879983037 1.0 0.365799897537423 22 O75976,Q9UIQ6,P16870,P02786 4 +Nucleobase containing compound transmembrane transporter activity 0.6304255937478552 1.802277556162865 0.0715017478535799 1.0 0.365799897537423 15 P51991,Q99808,Q9H2D1,Q8TB61,P41440 5 +Glucosidase activity 0.8055468239649585 1.8006394012077065 0.0717597346568124 1.0 0.365799897537423 5 P10253 1 +Rna strand annealing activity 0.8053763440860325 1.7999422808255583 0.0718697525752221 1.0 0.365799897537423 5 P23588,O00571,Q06787,P51114 4 +Phosphorus oxygen lyase activity 0.8542307222526417 1.7974358614756971 0.0722664518521907 1.0 0.365799897537423 4 O00584 1 +Intramembrane lipid transporter activity 0.7805447783357933 1.79561762040424 0.0725553515776706 1.0 0.365799897537423 6 Q9NV96,Q4KMQ2,Q7Z3C6 3 +Anion cation symporter activity 0.8497715667831112 1.779659574926529 0.0751316900323404 1.0 0.3724731085630033 4 Q9BXP2,Q15043,P55011 3 +Galactoside binding 0.9908675799086762 1.7794770477415736 0.0751615845791735 1.0 0.3724731085630033 2 P06280 1 +Neutral amino acid transmembrane transporter activity 0.7972379776765935 1.7666148009257443 0.0772927605285347 1.0 0.3804375874150252 5 P08195,Q96QD8 2 +Carnitine o acyltransferase activity 0.8438251024199097 1.7559189614788706 0.0791022468105016 1.0 0.3839779880542203 4 P23786 1 +Extracellular matrix structural constituent 0.8430382981923126 1.752774769404297 0.0796406756193519 1.0 0.3839779880542203 4 Q08431,P14543 2 +Solute cation symporter activity 0.6594522684401388 1.749189159399074 0.0802583273325177 1.0 0.3839779880542203 12 Q9H2J7,Q96QD8,Q9BXP2,P55011,Q15043,Q9Y6M7 6 +Ferrous iron binding 0.7922097134588584 1.7459768799596906 0.0808149693829562 1.0 0.3839779880542203 5 P22830 1 +Monooxygenase activity 0.6735937549186368 1.743807504159095 0.0811926615243399 1.0 0.3839779880542203 11 Q15800,Q16850,P19021,P30519 4 +Beta 2 microglobulin binding 0.982003760408274 1.7433367193013618 0.0812748149072919 1.0 0.3839779880542203 2 P55899 1 +Fibronectin binding 0.8404270185229972 1.7423348067732185 0.0814498762539255 1.0 0.3839779880542203 4 P06756,P07711 2 +Passive transmembrane transporter activity 0.5032494264811596 1.7350267744280694 0.0827360629201281 1.0 0.3877704261240161 41 Q96RD7,Q8TEL6,P06756,P21796,P45880,P51790,Q9C0H2,P51798,Q9H813 9 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.5055123483732751 1.7347310614712672 0.0827884518584332 1.0 0.3877704261240161 37 Q8NB78,P30519,Q32P28,O75845,O15460,Q15800,Q9UPP1,Q16850,P19021 9 +Cyclic nucleotide binding 0.7858527462932025 1.719835657152344 0.0854623190549452 1.0 0.3960302461682971 5 P10644 1 +Guanylate kinase activity 0.8331093791991294 1.7130394770445792 0.0867052771973884 1.0 0.39798012847124 4 Q14168,Q00013,O14936 3 +Sulfatide binding 0.8318196339395252 1.7078702626242974 0.0876604180953601 1.0 0.39798012847124 4 O14773 1 +Primary active transmembrane transporter activity 0.4762508494484916 1.7076079125132886 0.0877091192223118 1.0 0.39798012847124 58 O75380,O75306,Q7KZN9,P16615,P08183,Q15388,P33527,P51970,Q9H7F0,P51798,Q9NQ11,Q03519,O43676,Q04656,P98194,Q9NUT2,O96000,Q9Y6M9,P08574,O14678,Q9HD20,P05026 22 +Symporter activity 0.6252139937242666 1.7018515722902825 0.0887831959413192 1.0 0.4003515543689301 14 Q9H2J7,Q96QD8,Q9BXP2,P55011,Q15043,Q9Y6M7 6 +P type transmembrane transporter activity 0.7228369635242908 1.694979231041122 0.0900793607526553 1.0 0.4049387981822153 7 Q04656,P05026,P98194 3 +Growth factor receptor binding 0.5835069960542885 1.685829142240955 0.091828712963478 1.0 0.409730796672323 18 Q3ZCQ8,Q92542,O00560,P05067,Q9H2J4 5 +Axon guidance receptor activity 0.9664249261348372 1.6797250985385883 0.0930108141555414 1.0 0.4130021472594685 2 Q15375 1 +Copper ion binding 0.6435800104358411 1.6694548509016656 0.0950272709748265 1.0 0.4171117229093373 12 P19021,O60888,Q9NQ11 3 +Amino acid sodium symporter activity 0.9623959172710188 1.6632578921609722 0.0962608236474582 1.0 0.4171117229093373 2 Q9H2J7 1 +Organic acid sodium symporter activity 0.9623959172710188 1.6632578921609722 0.0962608236474582 1.0 0.4171117229093373 2 Q9H2J7 1 +Ganglioside binding 0.9708401895496316 1.6610698220422164 0.0966994245374164 1.0 0.4171117229093373 3 Q9UM22 1 +Glycosphingolipid binding 0.9708401895496316 1.6610698220422164 0.0966994245374164 1.0 0.4171117229093373 3 Q9UM22 1 +Organophosphate ester transmembrane transporter activity 0.6297213746464274 1.6595917275004886 0.0969966136657567 1.0 0.4171117229093373 13 Q8TB61,Q99808,Q9H2D1,P41440 4 +Nucleotide transmembrane transporter activity 0.6297213746464274 1.6595917275004886 0.0969966136657567 1.0 0.4171117229093373 13 Q8TB61,Q99808,Q9H2D1,P41440 4 +Pattern recognition receptor activity 0.9591727101799674 1.6500802290276562 0.0989265279224533 1.0 0.4200038553900652 2 Q5KU26 1 +Procollagen proline dioxygenase activity 0.8162891618207633 1.6454938970445296 0.0998680001969352 1.0 0.4227648288220114 4 Q32P28 1 +Magnesium ion transmembrane transporter activity 0.8115394231764141 1.6263711306328488 0.1038707283884983 1.0 0.4348155395155645 4 Q6P4Q7,Q8IUH4 2 +Laminin 1 binding 0.9613111230521222 1.6250990358154018 0.1041414583198938 1.0 0.4348155395155645 3 P14543,O94813 2 +Palmitoyl coa hydrolase activity 0.7051169793534869 1.6169567551761883 0.1058876159644333 1.0 0.4367864158532873 7 P50897,Q68D91 2 +Quaternary ammonium group binding 0.62070431736412 1.612636362060826 0.1068235337257601 1.0 0.4384776713494061 13 P21796,Q14108 2 +Ephrin receptor activity 0.946011281224822 1.5962427046369323 0.1104346165715912 1.0 0.4491626421903375 2 Q15375 1 +Sulfotransferase activity 0.9449368788611356 1.5918462246970269 0.1114192609086308 1.0 0.4519015833500894 2 Q7LGA3 1 +Glucosyltransferase activity 0.6541441715645268 1.5804574750135751 0.1140021381629787 1.0 0.4569106497818566 10 Q16739 1 +5 3 exodeoxyribonuclease activity 0.9417136717700844 1.578655786351188 0.1144150313467875 1.0 0.4569106497818566 2 Q8IV08 1 +Glucuronosyl n acetylgalactosaminyl proteoglycan 4 beta n acetylgalactosaminyltransferase activity 0.9374160623153422 1.561066724121997 0.1185080083912932 1.0 0.4675913809352114 2 Q8N6G5 1 +Opsonin binding 0.7943315439748395 1.5569288188485653 0.1194873863247276 1.0 0.4695605953931093 4 P06756 1 +L ornithine transmembrane transporter activity 0.935267257587971 1.5522716723868135 0.1205972330042051 1.0 0.4695605953931093 2 P30825 1 +Peptidyl proline dioxygenase activity 0.744873801349553 1.5500896136303182 0.1211200086134351 1.0 0.4695605953931093 5 Q32P28 1 +Metallopeptidase activity 0.4802807748139067 1.5498996380406995 0.1211656065546917 1.0 0.4695605953931093 41 P42892,Q9UIQ6,P02786,O75976,P16870 5 +Aromatic amino acid transmembrane transporter activity 0.9344614558152076 1.5489734721423427 0.1213880972435239 1.0 0.4695605953931093 2 P30825 1 +Folic acid transmembrane transporter activity 0.9339242546333592 1.5467746600412908 0.1219175926055111 1.0 0.4695605953931093 2 Q9H2D1 1 +Thiolester hydrolase activity 0.5591281411695477 1.541131446219329 0.1232847978629152 1.0 0.4725006666555088 18 Q9UMR5,P50897,Q68D91 3 +Amide binding 0.4801284676409649 1.5400339006254098 0.1235520901898687 1.0 0.4725006666555088 117 P42892,O14773,Q9UIQ6,P01130,P04439,P21796,Q8WTV0,Q15392,Q9UM22,P55899,Q9NQX7,P10321,P45880,P01889,Q9Y287,Q92673,P07602,Q07954 18 +O acyltransferase activity 0.5690657231012828 1.5345147592472292 0.1249030651109315 1.0 0.4725006666555088 16 Q8NCC3,Q9HCL2 2 +Amino acid cation symporter activity 0.9366474287991992 1.5318277963156377 0.1255649348601966 1.0 0.4725006666555088 3 Q9H2J7 1 +Coa hydrolase activity 0.6563537194490114 1.5273975264730482 0.1266621911597383 1.0 0.4740038700101547 9 P50897,Q68D91 2 +Carbohydrate derivative transmembrane transporter activity 0.625582743577668 1.5078173130754144 0.1316012898290537 1.0 0.484278443061914 11 Q8TB61,Q99808,P41440 3 +Adrenergic receptor binding 0.7819158071291485 1.5066855430807224 0.1318912789286654 1.0 0.484278443061914 4 Q07021,P46934 2 +Demethylase activity 0.61135982814737 1.505585406796661 0.132173637000174 1.0 0.484278443061914 12 Q9UPP1,Q8NB78 2 +Heparan sulfate proteoglycan binding 0.9229116304055928 1.5017001077604726 0.133174576063372 1.0 0.484278443061914 2 Q07954 1 +Transforming growth factor beta binding 0.9223744292237503 1.499501559236746 0.133743564509523 1.0 0.484278443061914 2 Q6YHK3 1 +Serine transmembrane transporter activity 0.779304909304622 1.496107019743919 0.1346257689204444 1.0 0.4862602399813067 4 Q96QD8,Q96NB2 2 +Sterol transfer activity 0.7303979970879634 1.489677937094932 0.1363089384625193 1.0 0.4899024223949953 5 Q96CP6,P61916,Q9H1P3 3 +Sphingomyelin phosphodiesterase activity 0.923042252357758 1.4803065173791607 0.1387914647400481 1.0 0.4911738015152423 3 Q92485 1 +Sh2 domain binding 0.620038151620894 1.4802222336200903 0.1388139487981015 1.0 0.4911738015152423 11 Q13501,Q14118 2 +Phosphatidylinositol monophosphate phosphatase activity 0.7244271678718837 1.4647027235485774 0.1430020415569641 1.0 0.4967439338294544 5 Q9NYA4 1 +Single stranded dna exodeoxyribonuclease activity 0.7702085926603451 1.459221125824874 0.1445042560536964 1.0 0.5007641522433586 4 Q8IV08 1 +C x3 c chemokine binding 0.9062583937684652 1.4335705929271043 0.1516948403981652 1.0 0.5146282903227484 2 P06756 1 +Collagen binding involved in cell matrix adhesion 0.906258393768465 1.4335705929271036 0.1516948403981655 1.0 0.5146282903227484 2 P17301 1 +Cell matrix adhesion mediator activity 0.906258393768465 1.4335705929271036 0.1516948403981655 1.0 0.5146282903227484 2 P17301 1 +Transporter activity 0.5709230825184474 1.431182680964107 0.1523778658267556 1.0 0.5148260225284882 201 Q93050,Q8TEL6,Q7Z3C6,Q8TB61,Q9NS69,O15173,O75306,Q96QD8,Q4KMQ2,P04062,Q8N4V1,Q9C0H2,Q9Y487,P55011,Q7KZN9,Q8WTV0,P17900,Q07820,Q96NB2,Q8IWT6,P06756,Q9BXW6,P61916,Q8IUH4,P33527,P51790,Q9H7F0,P51970,Q9Y666,P11166,P51798,Q9NQ11,P98164,Q9H813,Q96CP6,Q96RD7,Q9H2D1,Q9NWR8,Q8NE01,Q03519,O43676,Q04656,P98194,Q13423,Q9H2C2,Q9NV96,O96000,Q6P4Q7,Q15043,Q7L0J3,Q9Y6M9,P21796,P51991,Q99808,Q99595,P45880,Q9H2J7,Q9Y277,O14678,Q9BXP2,Q9Y619,Q8IXU6,P08195,P30825,P41440,P05026,Q9HD20,Q92581,O15118,Q8NHS3,Q9Y6M7 71 +Neurexin family protein binding 0.909457281031702 1.428841759872686 0.1530497199042679 1.0 0.5148260225284882 3 P16870,O00560 2 +Exodeoxyribonuclease activity 0.6347560577642917 1.425883123770548 0.1539020815643064 1.0 0.5151444331563259 9 Q8IV08 1 +Insulin like growth factor i binding 0.9074241651888182 1.4211394719620778 0.155276216870285 1.0 0.5151643574437527 3 P98164 1 +Amide transmembrane transporter activity 0.6453753760860623 1.4115621857213962 0.1580789132191662 1.0 0.5216604136232486 8 Q9H2D1,P33527,P41440 3 +Polypeptide n acetylgalactosaminyltransferase activity 0.7554071214722979 1.3991171176630364 0.1617778653636872 1.0 0.5278684505799411 4 Q86SF2,Q10472 2 +Beta galactosidase activity 0.8957829707225484 1.390759900093303 0.1642982467232392 1.0 0.5315366281515134 2 P16278 1 +Lysophosphatidic acid binding 0.8992456143547978 1.390159114196075 0.1644805658267381 1.0 0.5315366281515134 3 O14773 1 +Protein phosphatase activator activity 0.6841246237573899 1.385579591536856 0.1658753135511259 1.0 0.5319781709734035 6 Q16537,O94766 2 +Sphingosine n acyltransferase activity 0.8944399677679364 1.385274996000753 0.1659683963160825 1.0 0.5319781709734035 2 Q96G23 1 +Galactosidase activity 0.896023643202577 1.377956741391263 0.1682166445030741 1.0 0.535099846117649 3 P16278,P06280 2 +Iron ion transmembrane transporter activity 0.8922911630405654 1.376501151977285 0.1686665309153889 1.0 0.535099846117649 2 Q15043 1 +Phospholipid transporter activity 0.6118976843238346 1.37611853606113 0.1687849376872474 1.0 0.535099846117649 10 Q9H1P3,Q9NV96,Q4KMQ2,Q7Z3C6 4 +Voltage gated chloride channel activity 0.8936055883933348 1.368800283212191 0.1710617123533704 1.0 0.5364613527799004 3 P51798,P51790 2 +Modified amino acid transmembrane transporter activity 0.7003557926713795 1.3637353438753286 0.1726508759934251 1.0 0.53818705490426 5 Q9H2D1,P41440 2 +Iron ion binding 0.4821998537082342 1.3622301542598527 0.1731252622612187 1.0 0.53818705490426 29 P02792,Q32P28,O75845,O15460,P22830,Q15800,Q9UPP1,Q16850 8 +Guanosine diphosphatase activity 0.8885307547676684 1.361153298864597 0.173465249101373 1.0 0.53818705490426 2 Q8WVQ1 1 +Mannosyl oligosaccharide mannosidase activity 0.8871877518130526 1.355674027729913 0.1752029066189213 1.0 0.5408271227388902 2 P33908 1 +Phosphatidylinositol 3 5 bisphosphate phosphatase activity 0.6982814317592494 1.3550170448458176 0.1754121265221915 1.0 0.5408271227388902 5 Q9NYA4 1 +Histone methyltransferase activity h3 k9 specific 0.889947223778415 1.3549496746694143 0.175433591466954 1.0 0.5408271227388902 3 Q96KQ7 1 +Atpase coupled cation transmembrane transporter activity 0.5273471527175934 1.3493453633910957 0.177226061270582 1.0 0.5440427927376007 18 Q9H7F0,Q04656,Q9NQ11,Q9HD20,P05026 5 +Myosin binding 0.5588999811225863 1.3423519845332708 0.1794818953803152 1.0 0.5480654303006948 14 P11233,Q86VI3,Q96J84,Q15334,Q13049 5 +Solute proton antiporter activity 0.8850440225387814 1.3363918752779884 0.1814212205298013 1.0 0.5493089289229608 3 P51790 1 +Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity 0.7397172761226524 1.335332617760179 0.181767507629869 1.0 0.5493089289229608 4 Q9NYA4 1 +Nucleoside diphosphatase activity 0.8846021657363279 1.3347198922309094 0.1819680405040937 1.0 0.5493089289229608 3 Q8WVQ1 1 +Phosphatase activator activity 0.6370642517969917 1.3128485982601996 0.1892339703498906 1.0 0.5608530492548139 7 Q16537,O94766 2 +G protein coupled serotonin receptor binding 0.8782912412681342 1.310847214194339 0.1899093875379041 1.0 0.5608530492548139 3 P08754,P63096 2 +Peptidase regulator activity 0.4515989695076084 1.3048178242729809 0.1919548882489252 1.0 0.5608530492548139 35 P05067,Q06481,P53634 3 +Metallocarboxypeptidase activity 0.6652339008371843 1.3040054872328293 0.1922317114698728 1.0 0.5608530492548139 6 O75976 1 +Manganese ion transmembrane transporter activity 0.8764105319720565 1.30373608456752 0.192323581631514 1.0 0.5608530492548139 3 Q9HD20,Q15043 2 +Arylsulfatase activity 0.8761902307906979 1.30290320936067 0.1926078081258853 1.0 0.5608530492548139 3 P34059 1 +Cytokine receptor binding 0.4855928006165666 1.3024014558197063 0.1927791851844302 1.0 0.5608530492548139 25 Q9NXR7,P14174,P62993,Q3ZCQ8,P23458,Q96J02,O00560,Q9H2J4 8 +Phosphatidylinositol phosphate phosphatase activity 0.6211931489861912 1.299867448126229 0.1936464035415053 1.0 0.5608530492548139 8 Q9NYA4,Q96PE3,Q13614 3 +Metalloendopeptidase activity 0.5506689557213275 1.296930555753538 0.1946550818979244 1.0 0.5608530492548139 14 P42892,O75844 2 +Phosphatidylinositol bisphosphate phosphatase activity 0.6333120220775447 1.295916626423023 0.1950042104158771 1.0 0.5608530492548139 7 Q9NYA4,Q96PE3,Q13614 3 +Chloride channel inhibitor activity 0.6827272910232067 1.289583481380841 0.1971953140907369 1.0 0.5608530492548139 5 Q9UNK0,O15400 2 +Chloride channel regulator activity 0.6827272910232067 1.289583481380841 0.1971953140907369 1.0 0.5608530492548139 5 Q9UNK0,O15400 2 +Neurotransmitter transmembrane transporter activity 0.8705345151759469 1.287842183827829 0.1978009046923059 1.0 0.5609510031508363 2 Q9H2J7 1 +Fibroblast growth factor binding 0.6607047104147517 1.284411390563284 0.1989980495286238 1.0 0.5632459413558711 6 Q92896 1 +Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor 0.8622078968573721 1.2540203243833432 0.2098346181563584 1.0 0.5803927981310627 2 Q8IXB1 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.7187209894290756 1.2499537342653235 0.2113164486106655 1.0 0.5833298163168943 4 Q16850 1 +Deoxyribonuclease activity 0.494294705895638 1.246058991697647 0.212742738575651 1.0 0.5850425310830404 21 O00115,Q8IV08 2 +Cytoskeletal anchor activity 0.6086587035097484 1.2417130672043384 0.2143424469694124 1.0 0.5873488516323854 8 O00560 1 +Glucuronosyltransferase activity 0.7163317357710159 1.2402424663857867 0.2148857254823184 1.0 0.5873488516323854 4 Q9P2E5,O43505 2 +Insulin receptor binding 0.5945988364558931 1.2352137917881811 0.2167509476989473 1.0 0.5891992985841071 9 Q8WWQ0,O14654 2 +High density lipoprotein particle binding 0.8569930180469221 1.2304285137324271 0.2185366812416298 1.0 0.5891992985841071 3 Q9BQE5 1 +Protein self association 0.5170396277942878 1.2303923176235136 0.2185502287869856 1.0 0.5891992985841071 16 Q9Y282,Q13049,P11166,P53634 4 +Xenobiotic transmembrane transporter activity 0.6683755846834555 1.2291490268819594 0.2190159362589501 1.0 0.5891992985841071 5 P33527,P11166,P41440 3 +Clathrin binding 0.4724392134493325 1.2279883791841388 0.2194513303752447 1.0 0.5891992985841071 26 P01130,Q07954 2 +Macromolecule transmembrane transporter activity 0.5568532689417739 1.2229954719459173 0.2213314065448712 1.0 0.5909240150331545 12 Q9NS69,P51991,Q07820,Q99595 4 +Intracellular calcium activated chloride channel activity 0.8531491731715366 1.2159466658883402 0.2240052396445793 1.0 0.5932484097121092 3 Q9C0H2 1 +Ion gated channel activity 0.8531491731715366 1.2159466658883402 0.2240052396445793 1.0 0.5932484097121092 3 Q9C0H2 1 +Phosphatidic acid binding 0.6650530793327689 1.2151556460629749 0.2243067334242066 1.0 0.5932484097121092 5 Q9NQ11,Q8N3F8 2 +Hormone receptor binding 0.7088836315252907 1.2099816793541602 0.2262859229697658 1.0 0.5973948366401817 4 P23458 1 +Purine nucleotide transmembrane transporter activity 0.5657475476080286 1.2069174321636214 0.2274639435875507 1.0 0.5994149656789903 11 Q8TB61,Q99808,P41440 3 +Cation chloride symporter activity 0.8495432563138079 1.2023721714693427 0.2292193660914638 1.0 0.6013415216017437 3 Q9BXP2,P55011 2 +Potassium chloride symporter activity 0.8495432563138079 1.2023721714693427 0.2292193660914638 1.0 0.6013415216017437 3 Q9BXP2,P55011 2 +Ammonium transmembrane transporter activity 0.8493150684931496 1.2018091808467055 0.2294374676083788 1.0 0.6013415216017437 2 P55011 1 +L ascorbic acid binding 0.5730435542411649 1.185560967066123 0.2357957245541939 1.0 0.6109011502580508 10 P19021,Q32P28 2 +Udp glucosyltransferase activity 0.6370707794416853 1.1820259269238504 0.237195413525681 1.0 0.6128251609240016 6 Q16739 1 +Calcium channel inhibitor activity 0.8439430566747319 1.1801206533146045 0.2379522313373181 1.0 0.6133696616650375 2 Q9UKS6 1 +Nadh dehydrogenase activity 0.4808499410746918 1.158134065594698 0.2468093301504099 1.0 0.6229715973767991 21 O95831,O43676,P51970,O96000,Q9Y6M9 5 +5 3 exonuclease activity 0.5545775615201278 1.1501305980392087 0.2500900855677379 1.0 0.6282539865819299 11 Q8IV08 1 +Amp activated protein kinase activity 0.6460176358340639 1.1350178209163602 0.2563678516345109 1.0 0.6390809049860643 5 P17612,P22694 2 +Phosphatidylinositol 3 kinase regulator activity 0.8315874294923407 1.1304104776135318 0.2583033011873725 1.0 0.6393627792445666 2 O00459 1 +Nitric oxide synthase regulator activity 0.6444592300542267 1.128462343943717 0.2591247112802 1.0 0.6393627792445666 5 P00533 1 +Phospholipid scramblase activity 0.8297042312928655 1.1279149532002748 0.2593558381370866 1.0 0.6393627792445666 3 Q7Z3C6 1 +Proton transmembrane transporter activity 0.4288400694178946 1.1184211604031695 0.2633871610277243 1.0 0.6440640915818885 37 Q93050,P51790,Q13423,Q9Y487,Q92581 5 +1 phosphatidylinositol 4 kinase activity 0.6854505625229532 1.1149804493626818 0.2648587997739673 1.0 0.6451349304308686 4 Q8TCG2 1 +Chemokine binding 0.8254109692434091 1.111861519523058 0.2661976959738479 1.0 0.6451349304308686 3 P06756 1 +Endopeptidase regulator activity 0.450912695966186 1.110733592727322 0.2666830381030312 1.0 0.6451349304308686 28 P05067,Q06481 2 +Protein kinase a catalytic subunit binding 0.6182570560376716 1.1004748422468733 0.2711252850889538 1.0 0.6507006842134891 6 P10644 1 +Translation repressor activity 0.5640707615487862 1.0891323095861536 0.2760955437788688 1.0 0.6517302273963095 9 Q14011,Q06787,Q00577,P00374 4 +P type calcium transporter activity 0.6785810266057355 1.0872180362958306 0.2769404616415447 1.0 0.6517302273963095 4 P20020,P98194,P16615 3 +Lipid transfer activity 0.5744655593908747 1.0825221442127084 0.2790205811649402 1.0 0.653783259711092 8 Q96CP6,P61916,Q9H1P3 3 +Hydrolase activity hydrolyzing n glycosyl compounds 0.5496670359015223 1.0701445858665417 0.2845542327745485 1.0 0.661075547918669 10 P13051 1 +Catalytic activity acting on a glycoprotein 0.8135411069317539 1.0676106495504842 0.2856961777808346 1.0 0.661075547918669 3 O43505,Q10469 2 +Cation cation antiporter activity 0.8127250134245991 1.0645760563342048 0.2870678197856293 1.0 0.661075547918669 3 Q92581 1 +Lrr domain binding 0.8112327189453847 1.059029826898677 0.289586196122626 1.0 0.661075547918669 3 Q9Y6N7 1 +Cell adhesion mediator activity 0.4596895663615973 1.0542448787890248 0.2917708178503422 1.0 0.661075547918669 22 P17301,P35613,Q14126,Q9UQB8,Q08722,P78310,P05556 7 +Peptidase activator activity 0.5160457816724635 1.0536193801434952 0.2920572126699281 1.0 0.661075547918669 13 P05067 1 +Protein transmembrane transporter activity 0.5355427144568601 1.053103117985747 0.2922937339970974 1.0 0.661075547918669 11 Q9NS69,Q07820,Q99595 3 +Flippase activity 0.8074267797656144 1.0449014645770578 0.2960685128325906 1.0 0.6644381462641755 3 Q9NV96 1 +Atpase coupled intramembrane lipid transporter activity 0.8074267797656144 1.0449014645770578 0.2960685128325906 1.0 0.6644381462641755 3 Q9NV96 1 +Protein tyrosine phosphatase activity 0.4816757072383366 1.0428398555178224 0.2970224690144067 1.0 0.6655503472359855 17 Q3ZCQ8,Q9NYA4,Q9ULE6,Q13614,P10586 5 +Chemoattractant activity 0.6665416586128354 1.0386975342955524 0.2989454282751307 1.0 0.6668214977975566 4 P14174 1 +Oxidoreductase activity acting on nad p h 0.4382679464973448 1.0371191807363105 0.2996803171577462 1.0 0.6668214977975566 29 O95831,O43676,P51970,Q13423,O96000,Q7KZN9,Q9Y6M9 7 +C2h2 zinc finger domain binding 0.6659442915041989 1.0362951882172855 0.3000644502962357 1.0 0.6668214977975566 4 Q96KQ7 1 +Annealing activity 0.5419649281493694 1.0320597184890312 0.3020441426079858 1.0 0.6668214977975566 10 P23588,O00571,Q06787,P51114 4 +Intraciliary transport particle b binding 0.8006983615363923 1.0074713244038351 0.3137083311516166 1.0 0.6745934628308525 2 A0AVF1 1 +Semaphorin receptor activity 0.6576175151460903 1.002866426962583 0.3159253131714736 1.0 0.6745934628308525 4 P51805,O14786 2 +Pdz domain binding 0.476633372092062 0.9897476998586516 0.3222974538629801 1.0 0.6792248196483311 16 Q9ULH0,P51790,Q9Y624,P78310 4 +Frizzled binding 0.7921003286984847 0.9882733261761516 0.3230188051961205 1.0 0.6792248196483311 3 O00560 1 +Protein demethylase activity 0.5417465050089169 0.9821080402310884 0.3260466248587375 1.0 0.6792248196483311 9 Q8NB78 1 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.5637921639988721 0.9811073953668372 0.3265397839022106 1.0 0.6792776020429939 7 Q9UHG3 1 +Beta 2 adrenergic receptor binding 0.7902229384904799 0.966322648570762 0.3338827563789157 1.0 0.6896127485948587 2 P46934 1 +Ribosomal small subunit binding 0.5048848464719939 0.9495099076798996 0.3423613353722832 1.0 0.6988046046541216 12 P23588,O00571,P13051 3 +Mrna 3 utr binding 0.4046808172366895 0.9452467061164894 0.3445329395791874 1.0 0.6996668926838883 49 P35637,P31483,Q14103,Q9BWF3,Q92804,Q01085,P51114,P22626,Q06787,P51116,Q9Y6M1,Q14011 12 +Inorganic anion exchanger activity 0.7816277195810032 0.9328081777224108 0.3509190181693884 1.0 0.7053413583723279 2 Q9Y6M7 1 +Structural constituent of postsynapse 0.5930047709995423 0.9133095739999924 0.3610797484560986 1.0 0.7094278988533355 5 Q12959 1 +Oxidoreductase activity acting on a heme group of donors 0.5487150731615658 0.9130331503175892 0.3612251068606738 1.0 0.7094278988533355 7 Q7KZN9,P16435 2 +Phosphoric ester hydrolase activity 0.3661361348464668 0.9093204838513316 0.3631809811423638 1.0 0.7106398617117888 72 Q92485,Q8IV08,Q3ZCQ8,Q9NYA4,Q92484,P22413,Q9ULE6,Q9UNW1,Q13614,Q9NX62,P10586,Q12959,P34913,Q9H3S7,P11117 15 +Lipase activity 0.4313558523842948 0.9080795992809826 0.3638361680308462 1.0 0.7106398617117888 24 Q92485,Q8IV08,Q92484,Q8NHP8,Q8NCC3 5 +Dystroglycan binding 0.5453290851758357 0.8977842169772196 0.3693006006253467 1.0 0.716877636508026 7 Q14118 1 +Polyubiquitin modification dependent protein binding 0.4567632244477316 0.8908464524280587 0.3730115505879887 1.0 0.7186915745265993 17 Q9NXR7,Q13501 2 +Sulfur compound transmembrane transporter activity 0.5220362647991086 0.8877914293432292 0.3746529540177254 1.0 0.7186915745265993 9 Q70HW3,Q8TB61,P33527,Q9UBX3 4 +Cyclic nucleotide phosphodiesterase activity 0.7636314799892552 0.8634657833607278 0.3878814243660691 1.0 0.7202704572509359 2 P09543 1 +2 oxoglutarate dependent dioxygenase activity 0.4441290911235045 0.8588496048493189 0.390423495946921 1.0 0.7202704572509359 19 Q9UPP1,Q32P28 2 +Potassium ion transmembrane transporter activity 0.5345364554133721 0.849304903797419 0.3957116528783888 1.0 0.7202704572509359 7 Q9BXP2,Q92581,P05026,P55011 4 +17 beta hydroxysteroid dehydrogenase nadpplus activity 0.7533401713597027 0.8474879526361458 0.396723199298969 1.0 0.7202704572509359 3 P56937 1 +Atpase activator activity 0.4771029863013764 0.8420206348868087 0.3997764032707676 1.0 0.721984250683028 13 Q99543,P05026,Q8IXB1,Q96KC8 4 +Endodeoxyribonuclease activity 0.4689736669020178 0.840637728321515 0.4005509159248455 1.0 0.722158591352991 14 O00115 1 +Protein binding involved in heterotypic cell cell adhesion 0.5573360396678212 0.8382520220007258 0.4018891755195692 1.0 0.722158591352991 6 Q08722,P78310 2 +Phosphatidylinositol kinase activity 0.5528607218380776 0.8192350600143091 0.4126523153367165 1.0 0.7300572373035148 6 Q8TCG2 1 +Long chain fatty acid transporter activity 0.5683601028389706 0.8119196929204838 0.4168377137058536 1.0 0.7339185694950439 5 P11166 1 +Poly g binding 0.5510695699930024 0.8116383357236606 0.4169991872130931 1.0 0.7339185694950439 6 O14979 1 +Oxidoreduction driven active transmembrane transporter activity 0.4089633839461515 0.8000733194260236 0.4236683183759071 1.0 0.7367262254872062 28 O43676,P51970,O75306,O96000,Q7KZN9,Q9Y6M9 6 +Protein kinase a regulatory subunit binding 0.4837620697869285 0.7892369800918071 0.4299735120085932 1.0 0.7454301702876829 11 Q9Y6W5,O43164,O43823,P17612 4 +Gtpase activating protein binding 0.6021483900766798 0.7841736480417787 0.4329382254750844 1.0 0.746834270819145 4 P08754 1 +Protein tyrosine kinase binding 0.4148817797568676 0.7830531012509779 0.433595929959049 1.0 0.746834270819145 23 Q13501,Q07666,P05556 3 +Actinin binding 0.5154754355768114 0.7642950245314133 0.444691449725596 1.0 0.7587449882509583 7 Q14118 1 +Phospholipase activity 0.4204660667466842 0.7587494554271864 0.448002446543092 1.0 0.7622719790216413 21 Q92485,Q8NCC3,Q8IV08,Q8NHP8 4 +Channel regulator activity 0.427473283259104 0.7530010034529705 0.451449311027196 1.0 0.7639955871323947 19 Q9NWR8,Q9UKS6,Q9UNK0,O15400,P46934,Q9UEU0 6 +Poly a binding 0.4663624290207443 0.7469204520128856 0.4551115797168936 1.0 0.7648402936908907 12 O14979,Q07666,P31483 3 +Chemokine receptor binding 0.5352206326290131 0.7448264604385731 0.4563766365501642 1.0 0.765770815980045 6 P23458 1 +Phosphoprotein binding 0.3943403552603507 0.741211573648289 0.4585651670459043 1.0 0.7670928831228722 31 P62993,O00255,P42345,O00459,P46108,Q8IWS0,P11717,P07947,P46934 9 +Procollagen proline 4 dioxygenase activity 0.7214806217369668 0.735319316052576 0.462145047019364 1.0 0.7704186088084002 3 O15460 1 +Mirna binding 0.4417423022048067 0.7316912805084371 0.4643570196535642 1.0 0.7723326374993988 15 Q9BWF3,P22626,P67809,Q06787,P43243,P98175 6 +Non membrane spanning protein tyrosine kinase activity 0.5295818572429153 0.7212558900516293 0.4707520905896976 1.0 0.7811927044729952 6 P23458 1 +Phosphotyrosine residue binding 0.4666936880872753 0.7030767751221811 0.482007904896371 1.0 0.7906694074126956 11 P07947,O00459,P62993 3 +Transcription corepressor binding 0.4359617869762795 0.6984353421295971 0.4849049805034049 1.0 0.7937790661679188 15 Q9H9B1,Q96KQ7 2 +Poly purine tract binding 0.427382163780984 0.6951617311069861 0.486953952046989 1.0 0.7944462228901438 16 Q06787,O14979,Q07666,P31483 4 +Cyclic nucleotide dependent protein kinase activity 0.522514895349384 0.6918860628361919 0.4890088837603641 1.0 0.7947299317415604 6 P17612,P22694 2 +Camp dependent protein kinase activity 0.522514895349384 0.6918860628361919 0.4890088837603641 1.0 0.7947299317415604 6 P17612,P22694 2 +Signaling receptor binding 0.5082457714501873 0.6853563930751063 0.4931190541496508 1.0 0.7964503521972114 211 Q9BQE5,P14174,Q3ZCQ8,P01889,Q13501,Q13740,P23458,Q14344,P04062,O75955,P06280,P63096,P46379,P05067,P16870,P07947,Q9Y624,Q9Y2I1,P17301,P06756,P11233,Q07021,Q92520,Q96J02,O94898,P04899,P67870,P08236,Q7KYR7,O60716,P0DP25,P29992,Q5ZPR3,Q9H2J4,Q96RD7,Q9NPF0,Q92896,P04439,P62993,O14641,P08754,Q03519,Q9BY67,O14654,P09471,Q8WWQ0,P14635,O14936,O00459,P07942,P46934,P05556,Q9NXR7,Q08431,Q92542,Q00013,O94813,Q15375,O00560,P78310,P41440,Q07954 62 +Peroxisome targeting sequence binding 0.7107171635777804 0.668036754799526 0.5041101311690359 1.0 0.8054739989547532 2 Q9NXR7 1 +Transforming growth factor beta receptor binding 0.6963254285133482 0.6498029940205748 0.5158194847310882 1.0 0.8175627362167867 3 Q8WUH2 1 +Phosphatidylinositol binding 0.3520555257392322 0.6437605319729571 0.5197307307206784 1.0 0.8187329077588424 67 Q9H4A6,O14964,Q9P2R3,P53365,Q96L92,Q6ZVM7,Q9H1P3,Q9H3E2,Q12792,Q92783,Q06481,O00560,Q8WTV0,Q9H0H5,Q9NQ11,Q9Y2I1 16 +Molecular function activator activity 0.4332225169052197 0.6415499517065673 0.521165437786343 1.0 0.8187329077588424 14 Q99543,P05026,Q8IXB1,Q96KC8 4 +Peptidyl proline 4 dioxygenase activity 0.5633460837242847 0.6377827756432464 0.5236150933674555 1.0 0.8187329077588424 4 O15460 1 +Poly pyrimidine tract binding 0.4252562377738201 0.6371009614466755 0.5240590823507163 1.0 0.8187329077588424 15 Q06787,P31943,Q07666 3 +Nucleobase containing compound kinase activity 0.3984968012117624 0.6135214873863359 0.539531579433898 1.0 0.8316346638407854 21 Q5KU26,Q14168,O14936 3 +Estradiol 17 beta dehydrogenase activity 0.5180460923194029 0.6115513691514379 0.5408346216111963 1.0 0.8318769815460351 5 P56937 1 +Cytokine activity 0.4801419096392506 0.6098780171722781 0.5419426155787621 1.0 0.8326991299686377 7 P14174 1 +Acetylcholine receptor binding 0.6894977168949863 0.5942871744612769 0.5523200553883267 1.0 0.8401887356429101 2 Q15334 1 +Calcium ion transmembrane transporter activity 0.4098039677086223 0.5910881984886793 0.5544613268079308 1.0 0.8406892037649771 16 Q96RD7,P06756,P08195,Q8TEL6 4 +Tropomyosin binding 0.6767866738312678 0.5856716340011865 0.5580961996951956 1.0 0.842797268443275 3 P28289,Q9NYL9 2 +Steroid dehydrogenase activity 0.4654484869318809 0.5823879481232315 0.560305397549187 1.0 0.8430709194211601 8 Q3SXM5,Q53GQ0,P56937 3 +G protein coupled receptor activity 0.6748735946093057 0.5795135171241312 0.5622427286094072 1.0 0.8441086598156284 3 P48960 1 +Hsp70 protein binding 0.4025246243506891 0.5771878196398866 0.5638125843604687 1.0 0.8441086598156284 18 P02786,Q99543,Q8IXB1,P46379 4 +Lipid binding 0.453643607742324 0.5686785371352817 0.5695743158436075 1.0 0.8441086598156284 170 O14773,Q9BQE5,Q9UM22,O15173,Q9NWW5,P04062,P07602,Q8WTV0,Q9Y2I1,Q9BXW6,P50897,P53365,P61916,O95772,A6NIH7,Q06481,P11717,Q14108,Q9NQ11,Q9H3E2,Q8NCC3,P21796,P45880,Q08431,Q9UKS6,Q92783,O00560,O15118 28 +Sodium ion binding 0.6806338973945727 0.5644440745590416 0.5724519506326708 1.0 0.8441086598156284 2 P05023 1 +Structural constituent of synapse 0.461185939202938 0.5636228005333676 0.5730108662971576 1.0 0.8441086598156284 8 Q12959,P56545 2 +Organic cation transmembrane transporter activity 0.4877938155615062 0.5510258189448355 0.58161597554048 1.0 0.8521759803075447 6 Q9H7F0 1 +Folic acid binding 0.6602401794352623 0.5331879248901826 0.5939034994254644 1.0 0.8613376438515306 3 P41440 1 +Phosphatidylinositol 3 kinase binding 0.4830909372437486 0.5324791782591545 0.5943941591868 1.0 0.8613376438515306 6 P0DP25,O14654 2 +Single stranded rna binding 0.3598261943457932 0.5290558166108075 0.5967667303233926 1.0 0.8621943208254388 41 P23588,P52597,P31483,O14979,O00257,P51114,Q9Y606,Q06787,Q07666,O00571,P07910,Q15056,P31943,Q13325 14 +Structural constituent of muscle 0.4444121271113146 0.5251328547347153 0.5994908379937134 1.0 0.8652690822732325 9 Q14118 1 +Pre mrna intronic binding 0.493936356158244 0.52029492843524 0.6028580301558257 1.0 0.8684026386768442 5 P22626 1 +Protein disulfide isomerase activity 0.4278143813058319 0.5108856658084822 0.6094311189081867 1.0 0.8734022579670417 11 Q96JJ7,Q6ZRP7,Q14554 3 +Cell cell adhesion mediator activity 0.3886494114673327 0.5086857333444769 0.6109725240498629 1.0 0.8734022579670417 19 P35613,Q14126,Q9UQB8,Q08722,P78310 5 +Translation initiation factor binding 0.3841694485548848 0.498899450333241 0.6178502213031312 1.0 0.8773756464046512 20 O15514,Q06787,Q13049,O00571,Q9UNK9 5 +Inositol phosphate phosphatase activity 0.5235063132300184 0.4965687746865416 0.6194931772997863 1.0 0.8773756464046512 4 Q9UNW1 1 +Flavin adenine dinucleotide binding 0.3628684521317734 0.4965343357890677 0.6195174684863063 1.0 0.8773756464046512 31 Q8NB78,Q15392 2 +Lipase binding 0.6583400483481077 0.4922111580217002 0.6225700773148548 1.0 0.8780730295469852 2 Q96CS3 1 +Atpase coupled inorganic anion transmembrane transporter activity 0.6425643445211737 0.4792150277548616 0.6317856644773767 1.0 0.8828674621268349 3 P51798 1 +Protein kinase a binding 0.3809582166572988 0.4785639592051622 0.6322488631200844 1.0 0.8828674621268349 20 Q9Y6W5,O43823,P10644,O43164,P17612 5 +Regulatory rna binding 0.3840585093432493 0.4649325026332591 0.6419797937447029 1.0 0.8920140292031662 18 Q9BWF3,P22626,P67809,Q06787,P43243,P98175 6 +Acyltransferase activity 0.3418578233277974 0.4604959545193325 0.6451602745958522 1.0 0.8955762129189077 62 Q96G23,Q86UY6,Q9UJ14,Q8IUH4,Q96QD8,P23786,Q8NCC3,Q9HCL2 8 +Oxidoreductase activity acting on single donors with incorporation of molecular oxygen 0.6333813111525357 0.4521099990172002 0.6511897406977347 1.0 0.8988745822958794 3 Q96SZ5 1 +Isocitrate dehydrogenase activity 0.4590189225130934 0.3960639171520987 0.6920578762548311 1.0 0.9356300486837013 5 P48735 1 +Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 0.6116814017558327 0.3908503657721396 0.695907843726812 1.0 0.9356300486837013 3 O75845 1 +Protein phosphatase regulator activity 0.3665936363890821 0.3885547213587863 0.697605566858617 1.0 0.9356300486837013 20 Q86XL3,Q01105,O94766,P0DP25,Q16537 5 +Eukaryotic initiation factor 4e binding 0.4890230645363852 0.3846707313078135 0.7004813826903404 1.0 0.9356300486837013 4 Q9UNK9 1 +G protein activity 0.3829107005644103 0.3710325108103893 0.7106133171339493 1.0 0.9397181570842388 14 P11233,Q9H0U4,P61225 3 +Channel inhibitor activity 0.4389276496849326 0.366738669989703 0.7138139588401073 1.0 0.9413786269171988 6 Q9UKS6,P46934 2 +Omega peptidase activity 0.3425343666745506 0.3407961024101397 0.733257084837917 1.0 0.9489209333196572 31 Q96FW1,Q9UJ14,Q96K76,Q92820,Q96RU2,Q9H8M7,Q9UPT9,Q92560,Q8NB14,Q93009 10 +N6 methyladenosine containing rna binding 0.4691803992285602 0.3257224428659456 0.7446343625096765 1.0 0.9537789564609604 4 P22626 1 +Calcium channel regulator activity 0.4372202927526721 0.3245121104945742 0.7455503550848417 1.0 0.9537789564609604 5 Q9UKS6 1 +Phosphatase binding 0.3345439203289447 0.3133202590282375 0.7540373599864274 1.0 0.9553771786215468 52 Q8IV63,Q8TEL6,Q86XL3,P62993,P53634,Q9NYA4,Q92845,P19022,Q15334,P23458,Q12959,P00533,O00459,P35222,P78318 15 +Nadp binding 0.356377098555066 0.2932422453219247 0.7693369955301121 1.0 0.9651100866430388 17 Q13423,O75874,Q9UBM7 3 +Quinone binding 0.4266433589861406 0.2917557441132019 0.7704733847773166 1.0 0.9651100866430388 5 Q8N0U8 1 +Protein carboxyl o methyltransferase activity 0.5710068020429758 0.2879237124647657 0.773405135239235 1.0 0.9651100866430388 3 O60725 1 +Phosphatidylinositol 3 4 bisphosphate binding 0.5815202793446103 0.2813425260466373 0.7784476958885285 1.0 0.9651100866430388 2 O75146 1 +O methyltransferase activity 0.3916195701967887 0.2775531722325269 0.7813553832746085 1.0 0.9666338527504056 8 P21964 1 +G rich strand telomeric dna binding 0.4163895300343196 0.2613395254578015 0.7938306884322353 1.0 0.9721385615854398 5 P09651,P22626 2 +Transferase activity transferring sulphur containing groups 0.3671454049291848 0.2548229207083889 0.7988598713709358 1.0 0.9754233414569824 12 Q7LGA3,Q8NCH0 2 +Proline rich region binding 0.3851368654552907 0.253501450542826 0.7998807403956825 1.0 0.9754233414569824 8 Q9UQB8,P46934 2 +Protein serine threonine kinase activator activity 0.3756930505069251 0.2514230158079595 0.8014870750451775 1.0 0.9754233414569824 10 P0DP25,P14635,O00571 3 +Threonine type peptidase activity 0.3789093145268569 0.2488874074031917 0.8034478762965227 1.0 0.9754233414569824 9 Q99436,P49721,Q9UJ14 3 +Phosphatase regulator activity 0.3358218841638706 0.2466188565482487 0.8052032098128006 1.0 0.9767377281939736 23 Q86XL3,Q01105,Q16537,O94766 4 +Oxidoreductase activity acting on nad p h heme protein as acceptor 0.4380384917486544 0.2426477533754583 0.8082782846431522 1.0 0.9789909415190732 4 Q7KZN9 1 +Dopamine receptor binding 0.4097831899944523 0.242478794030887 0.8084091865574166 1.0 0.9789909415190732 5 Q14344,Q15334 2 +Metallochaperone activity 0.434733186572789 0.234565820842109 0.8145457404518839 1.0 0.9832995061097818 4 Q04656 1 +Copper chaperone activity 0.434733186572789 0.234565820842109 0.8145457404518839 1.0 0.9832995061097818 4 Q04656 1 +Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor 0.3990767830687418 0.234398232779094 0.814675830475253 1.0 0.9832995061097818 6 P56937 1 +Cysteine type exopeptidase activity 0.555197421434325 0.2251428001537594 0.8218681858708856 1.0 0.9894261874450496 2 Q0VDG4 1 +Peptide transmembrane transporter activity 0.4296870575979857 0.2225131372780274 0.823914447530468 1.0 0.9894261874450496 4 P33527 1 +Smad binding 0.3515908060919079 0.2146557136001004 0.8300357530787001 1.0 0.9935794834874464 14 Q96QR8,Q9UNE7,Q8WUH2,P35222,Q00577 5 +O acetyltransferase activity 0.53356535328523 0.2087357838410172 0.8346545039361375 1.0 0.9966087165906358 3 P43155 1 +Lyase activity 0.3159782849936878 0.2071079762042756 0.8359255330382624 1.0 0.9966087165906358 63 O00584,P22830,Q8NBZ7,O60266,P19021,P53701 6 +Double stranded rna adenosine deaminase activity 0.5425731936610136 0.2013697285339883 0.8404094835028453 1.0 0.9977715208880876 2 Q9NZI8 1 +Mhc class ib protein binding 0.5276732939279865 0.1977319550426224 0.8432547867886528 1.0 0.9986492179553912 3 Q03519,Q9NUQ9 2 +Transferrin receptor binding 0.418435904326795 0.1969075878702824 0.8438998556689152 1.0 0.9986492179553912 4 O60749,O95219,Q13596 3 +Oxidative rna demethylase activity 0.5369325812516659 0.1914206709142572 0.8481960264457289 1.0 1.0 2 Q6P6C2 1 +Protein phosphorylated amino acid binding 0.3363171147369032 0.1841968084949736 0.8538590630979543 1.0 1.0 17 P07947,O00459,P46934,P62993 4 +Protein macromolecule adaptor activity 0.3410398345279136 0.1826166559391058 0.8550988145638905 1.0 1.0 106 Q8TEL6,Q9H270,O15400,Q9UEU0,Q99747,Q13190,O95249,Q07666,P51809,O95721,P54920,Q9P2W9,O14641,Q86Y82,Q5SQN1,O43752,Q9UQB8,Q92542,O00161,Q9UNK0,Q96D46,Q9BTX1,O00560,Q9NZ43,P05026 25 +Pyruvate dehydrogenase acetyl transferring kinase activity 0.5099408919935428 0.1670685346563512 0.8673161237208702 1.0 1.0 3 Q15120,O14874 2 +Phosphatidylinositol phosphate 4 phosphatase activity 0.5085975282106298 0.1648960633477186 0.8690257909791648 1.0 1.0 3 Q9NTJ5,Q96PE3 2 +Nad binding 0.3193977332430801 0.1610779235475702 0.8720320276370954 1.0 1.0 30 Q13423,Q8NBZ7,P48735 3 +Gpi anchor binding 0.5056421278882236 0.1601912201678849 0.8727304453738784 1.0 1.0 3 O43292,Q9H490 2 +Gtp dependent protein binding 0.354703257543391 0.1599402404262257 0.8729281492529817 1.0 1.0 9 P53365,Q86YV9 2 +Gdp dissociation inhibitor activity 0.3694541543425622 0.1499470802181222 0.8808063669455009 1.0 1.0 6 P31150,P24386,P43487,P55010,P50395 5 +Translation activator activity 0.4967759269210002 0.1466906675920086 0.8833761850991975 1.0 1.0 3 Q7Z478,Q6PKG0 2 +Histone deacetylase activity h3 k14 specific 0.5073865162503334 0.1460412512113769 0.8838888237521298 1.0 1.0 2 Q13547 1 +Calmodulin dependent protein kinase activity 0.4951044866113337 0.1442483892402679 0.8853043313828619 1.0 1.0 3 Q14012 1 +Lysine n methyltransferase activity 0.3266860430880461 0.1324027950879698 0.8946657039813666 1.0 1.0 16 Q96KQ7 1 +Histone lysine n methyltransferase activity 0.3266860430880461 0.1324027950879698 0.8946657039813666 1.0 1.0 16 Q96KQ7 1 +Plus end directed microtubule motor activity 0.3619654442926799 0.1307542373995878 0.8959697253632166 1.0 1.0 6 P33176 1 +Nitric oxide synthase binding 0.3807474803595174 0.1243507895306981 0.9010375350996732 1.0 1.0 4 P0DP25 1 +Molecular function inhibitor activity 0.3387469080807369 0.1205849035091629 0.9040198268337538 1.0 1.0 11 Q9UKS6,P46934,Q9NWR8 3 +Nucleoside monophosphate kinase activity 0.3409781848384147 0.1196049926517134 0.9047960645552364 1.0 1.0 10 Q14168,O14936 2 +Translation repressor activity mrna regulatory element binding 0.3564035974745984 0.1170955866520167 0.9067843070195736 1.0 1.0 6 Q00577,P00374 2 +14 3 3 protein binding 0.3751679656006392 0.1153667306065979 0.9081544479832592 1.0 1.0 4 O14974,P78362,Q9UBF8 3 +Myosin v binding 0.3564516129032188 0.1136460886385185 0.9095183505503754 1.0 1.0 5 P20337,P61106,P61026,P61006 4 +Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor 0.3561827956989181 0.1131090959872625 0.909944063718776 1.0 1.0 5 P11177,P08559,Q02218,Q96HY7 4 +Y form dna binding 0.4685652874798406 0.1097649191390631 0.9125958133567658 1.0 1.0 3 O00255,P54132 2 +Dicarboxylic acid transmembrane transporter activity 0.3408162573346582 0.1059541764173178 0.9156187093756112 1.0 1.0 8 P41440,Q9UBX3 2 +Histone methyltransferase activity 0.313118206493517 0.1050202060471811 0.916359775273051 1.0 1.0 23 Q9H9B1,Q96KQ7 2 +Nad dependent protein deacetylase activity 0.3681805966138134 0.1047515688215198 0.9165729410131412 1.0 1.0 4 Q13547,Q92769,Q8IXJ6 3 +Cyclin dependent protein serine threonine kinase inhibitor activity 0.4705882352941 0.1046027075265671 0.9166910661991912 1.0 1.0 2 O94992 1 +Racemase and epimerase activity acting on carbohydrates and derivatives 0.4613111230521117 0.101710142075961 0.9189867516860022 1.0 1.0 3 Q9Y223,Q14376 2 +K48 linked polyubiquitin modification dependent protein binding 0.3492874428609732 0.1003755752970438 0.9200461599103054 1.0 1.0 6 P55072,Q96EP0,Q04323,Q92890,Q9NRR5 5 +3 hydroxyacyl coa dehydratase activity 0.4638732205210742 0.0986985273709526 0.9213776381453372 1.0 1.0 2 Q6Y1H2 1 +Phospholipase c activity 0.4583557227297089 0.0985914950510587 0.9214626230859642 1.0 1.0 3 P30101,P16885 2 +Inositol trisphosphate phosphatase activity 0.4559376679204626 0.0961089914329891 0.9234340102367986 1.0 1.0 3 Q96PE3,Q01968 2 +Phosphatidylinositol 4 5 bisphosphate phosphatase activity 0.4559376679204626 0.0961089914329891 0.9234340102367986 1.0 1.0 3 Q96PE3,Q01968 2 +Sequence specific mrna binding 0.3372895070128775 0.0925927335518968 0.926227116734065 1.0 1.0 7 Q06787 1 +Dioxygenase activity 0.3108216446931839 0.0884678244298776 0.9295048564276112 1.0 1.0 25 Q9UPP1,O15460,Q32P28 3 +Arylesterase activity 0.4488315874294918 0.0871470001811924 0.9305546667231612 1.0 1.0 2 Q15165 1 +Signaling receptor complex adaptor activity 0.3433718741597145 0.0871320373072842 0.9305665601283388 1.0 1.0 6 Q96T76,Q9UN86,P37198,Q06124,P46108 5 +Glucocorticoid receptor binding 0.4466827827021137 0.0856760382686921 0.9317239507651498 1.0 1.0 2 Q04917 1 +Actin monomer binding 0.3411290322580587 0.0849056068159983 0.9323364342917402 1.0 1.0 5 Q6IBS0,P35080,Q12792,Q9UHB6 4 +Nuclear receptor activity 0.4426537738383028 0.0830327240411504 0.9338255194245052 1.0 1.0 2 P10589 1 +17 beta hydroxysteroid dehydrogenase nadplus activity 0.3474872346143461 0.0773789403128398 0.9383220937403612 1.0 1.0 4 Q53GQ0,Q8NBQ5,P51659 3 +Clathrin light chain binding 0.4293390650187956 0.0727246691124625 0.9420252174112832 1.0 1.0 3 O75146,O00291 2 +Efflux transmembrane transporter activity 0.4281406808933287 0.0718321965546311 0.9427354498493852 1.0 1.0 3 P33527 1 +Abc type xenobiotic transporter activity 0.4281406808933287 0.0718321965546311 0.9427354498493852 1.0 1.0 3 P33527 1 +Histone methyltransferase binding 0.3356094845657609 0.0706686404282389 0.9436614797285232 1.0 1.0 6 P83916,Q13185 2 +Sh3 domain binding 0.3060670575407523 0.0607696249364529 0.9515426813854648 1.0 1.0 24 P62993,Q9Y6W5,Q14185,Q07666,P98164 5 +Protein tag 0.3542841794251984 0.0533682152060179 0.957438529699423 1.0 1.0 2 Q9BZL1 1 +Phosphatidylinositol 3 5 bisphosphate binding 0.3207903243393737 0.0528110547430204 0.9578824533824576 1.0 1.0 10 Q9NQ11 1 +Misfolded protein binding 0.3159595801555029 0.049517161699374 0.960507160917612 1.0 1.0 13 P46379,Q13217,Q8IXB1,P48723 4 +Insulin like growth factor receptor binding 0.3825900053734433 0.0467109434735752 0.9627436082371752 1.0 1.0 3 P46108,Q04917 2 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.3026749161203787 0.0435300098181537 0.9652790428162624 1.0 1.0 23 O43676,P51970,O96000,Q9Y6M9 4 +Protein tyrosine serine threonine phosphatase activity 0.3621425736644481 0.0400517053462052 0.9680519044302563 1.0 1.0 3 Q13614 1 +Ligase activity forming phosphoric ester bonds 0.3102150537634328 0.0384056527446203 0.9693642540703188 1.0 1.0 5 P18858,P49916,Q96JA1,Q9Y3I0 4 +Dna insertion or deletion binding 0.3036818059661297 0.0378423009749559 0.9698134172097646 1.0 1.0 4 P20585,P12004,P52701 3 +Nedd8 specific protease activity 0.3154218162278236 0.0318651094156161 0.9745796231541646 1.0 1.0 3 Q92905,Q96FW1 2 +Cytochrome b5 reductase activity acting on nad p h 0.2931219774314795 0.0301597396425912 0.9759396570243032 1.0 1.0 3 Q9UHQ9,P16435 2 +Phospholipase a2 inhibitor activity 0.253036672737332 0.028850022437358 0.9769842053282892 1.0 1.0 3 P04083 1 +Mrna 3 utr au rich region binding 0.3101179550363252 0.0258394696873732 0.9793853800913316 1.0 1.0 12 Q14103,Q01085,P31483 3 +Phosphatidylinositol 3 phosphate binding 0.3110871905274456 0.0254341018744539 0.979708710537408 1.0 1.0 9 Q9HAU0,Q8TEW0,O60493,Q9Y4P8,O95219,Q5MNZ6,O00291,Q96L92 8 +Oxidized dna binding 0.3039268423883943 0.0155411271238294 0.9876004737484004 1.0 1.0 7 P20585,P54132,P23396,P52701,P18887,Q14191 6 +N acyltransferase activity 0.2972934698797244 0.0129309642543672 0.9896828707868628 1.0 1.0 23 Q96G23,Q86UY6,Q96QD8 3 +Four way junction dna binding 0.3040086090933485 0.0101395706981535 0.9919099317115372 1.0 1.0 8 O15347,P54132,P52701,O00255,P09429,P26583,Q14191 7 +Phosphatase activity 0.299372753699646 0.0005861457326165 0.9995323233963443 1.0 1.0 55 Q3ZCQ8,Q9NYA4,Q9ULE6,Q9UNW1,Q9NX62,Q13614,P10586,Q12959,P34913,Q9H3S7,P11117 11 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..eb812b049c36a7361f77bfe3d6b9b21ee29f19a7 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 3 kinase regulator activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 cyclic amp phosphodiesterase activity", "3 5 cyclic gmp phosphodiesterase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "3 phosphoadenosine 5 phosphosulfate binding", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5alpha androstane 3beta 17beta diol dehydrogenase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylesterase activity", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminoacyltransferase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 1 adaptor complex binding", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Benzodiazepine receptor activity", "Benzodiazepine receptor binding", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Bile acid transmembrane transporter activity", "Bioactive lipid receptor activity", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide 1 phosphate binding", "Ceramide 1 phosphate transfer activity", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chitinase activity", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co receptor binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Collagen receptor activity", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Copper ion transmembrane transporter activity", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Corticotropin releasing hormone receptor binding", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor activity", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Delta catenin binding", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix constituent conferring elasticity", "Extracellular matrix protein binding", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Fatz binding", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibroblast growth factor receptor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gap junction channel activity", "Gap junction hemi channel activity", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyl n acetylgalactosaminyl proteoglycan 4 beta n acetylgalactosaminyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione hydrolase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophosphodiester phosphodiesterase activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Growth hormone receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanosine diphosphatase activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H3 histone acetyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate proteoglycan binding", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di methyl lysine 27 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "Hypoglycin a gamma glutamyl transpeptidase activity", "I smad binding", "Identical protein binding", "Igg binding", "Immune receptor activity", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol bisphosphate phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate kinase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interferon receptor activity", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Microtubule severing atpase activity", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin light chain binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosamine synthase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus nucleosidase activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nadplus nucleosidase activity", "Narrow pore channel activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neuregulin binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neuropeptide binding", "Neuropeptide receptor binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opioid receptor binding", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphatidylserine flippase activity", "Phosphatidylserine floppase activity", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphorylation dependent protein binding", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion antiporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Potassium proton antiporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein glutamic acid ligase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein hormone receptor activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase 2b binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoic acid responsive element binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Salt transmembrane transporter activity", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Selenium binding", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Short chain carboxylesterase activity", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine 1 phosphate receptor activity", "Sphingosine n acyltransferase activity", "Stat family protein binding", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo polymer binding", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Superoxide generating nadph oxidase activator activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toll like receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor binding", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type 1 fibroblast growth factor receptor binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific endopeptidase activity", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor activated receptor activity", "Vascular endothelial growth factor binding", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Wnt protein binding", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD16A", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACE2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADAT3", "ADCY3", "ADD1", "ADD2", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALG9", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APBB1", "APC", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APOL2", "APP", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID4B", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL8B", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASNSD1", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATM", "ATP11C", "ATP13A1", "ATP13A2", "ATP13A3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATPIF1", "ATRN", "ATRX", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP1", "BAP18", "BARD1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCAT1", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCL10", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BEND3", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BSG", "BTAF1", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C10orf88", "C1QBP", "C1orf123", "C1orf35", "C2CD5", "CAB39", "CABIN1", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CASP8AP2", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX4", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCNB1", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD276", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC6", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK7", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPV", "CEP250", "CEP290", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHMP2B", "CHMP3", "CHMP5", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIT", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLK2", "CLK3", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT9", "CNP", "COASY", "COCH", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2L", "CPD", "CPE", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CREG1", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTBS", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DMD", "DMXL2", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4ENIF1", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENPP4", "ENTPD7", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC3", "ERH", "ERI1", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM105A", "FAM120A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM83D", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FAT1", "FAU", "FBL", "FBXO21", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNBP1", "FNDC3A", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALE", "GALK1", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GGT7", "GHDC", "GID4", "GID8", "GIGYF2", "GIT1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPT2", "GPX8", "GRAMD1A", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS4", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "JAK1", "JUP", "KARS", "KAT5", "KAT7", "KATNA1", "KCTD10", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1147", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFAP3", "KIFBP", "KIFC1", "KIN", "KIRREL1", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDB1", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN2", "LMAN2L", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRIG1", "LRIG2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LZIC", "LZTFL1", "M6PR", "MACF1", "MACROD1", "MAGED1", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4", "MAP4K4", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBLAC2", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED27", "MEN1", "MEPCE", "MESD", "METAP2", "METTL13", "METTL15", "METTL17", "METTL7B", "MFAP1", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGA", "MGAT2", "MGEA5", "MGRN1", "MGST2", "MGST3", "MIA3", "MICAL3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKL2", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MPV17", "MRC2", "MRE11", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA4", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDC80", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NEO1", "NES", "NEU1", "NF1", "NF2", "NFRKB", "NFS1", "NFU1", "NHP2", "NID1", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME4", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "OAT", "OBSL1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC1", "ORC2", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK2", "PALD1", "PALLD", "PAM", "PAN2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4K2B", "PI4KA", "PI4KB", "PIAS1", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGO", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLEKHA7", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNA3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POFUT2", "POLA1", "POLD1", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKACB", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PWP1", "PWP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB31", "RAB32", "RAB33B", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1CC1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOK2", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF149", "RNF20", "RNF213", "RNF219", "RNF31", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTF1", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP3", "SCAP", "SCARA3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL1", "SCYL2", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SELENOI", "SENP3", "SENP6", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGSH", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIAE", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG6", "SMN1*", "SMNDC1", "SMPD4", "SMPDL3A", "SMPDL3B", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX25", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORL1", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSFA2", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STK3", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYDE1", "SYNCRIP", "SYNE1", "SYNE2", "TAB1", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TAX1BP1", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRD7", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX2", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "TGS1", "THAP11", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TMCO1", "TMED10", "TMED9", "TMEM106B", "TMEM109", "TMEM115", "TMEM192", "TMEM201", "TMEM206", "TMEM30A", "TMEM38B", "TMEM43", "TMEM59", "TMEM70", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIO", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2B", "TRMT5", "TRMT6", "TRMU", "TROVE2", "TRPC4AP", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSPYL1", "TSR1", "TSR3", "TST", "TSTA3", "TTC1", "TTC21B", "TTC26", "TTC4", "TTF2", "TTK", "TTLL12", "TTLL4", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP1", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBIAD1", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "URB1", "URGCP", "UROD", "USE1", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP32", "USP33", "USP34", "USP36", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VLDLR", "VMP1", "VPS11", "VPS18", "VPS25", "VPS28", "VPS33B", "VPS35", "VPS37B", "VPS4A", "VPS4B", "VPS50", "VPS72", "VRK1", "VRK2", "VRK3", "VTI1B", "WARS", "WASF2", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR3", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WLS", "WNK1", "WNK2", "WRN", "WRNIP1", "WTAP", "WWP2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCCHC9", "ZDHHC13", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF131", "ZNF277", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF598", "ZNF622", "ZNF638", "ZNF644", "ZNF830", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCB8", "ABCC1", "ABCD4", "ACP2", "ADCY3", "ADGRE5", "ADO", "AGPS", "AIFM1", "AKAP8", "ALCAM", "ALG11", "ALG5", "ALKBH5", "ANGEL1", "ANKFY1", "ANKLE2", "ANO6", "ANXA1", "APLP2", "APOL2", "APP", "ARFIP2", "ARSA", "ARV1", "ATG9A", "ATP13A1", "ATP13A2", "ATP13A3", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP7A", "ATRN", "B3GAT3", "B4GALT3", "B4GAT1", "BABAM2", "BAG5", "BAG6", "BAIAP2", "BAP1", "BCKDK", "BLM", "BSG", "BTN2A1", "C1QBP", "CADM1", "CALM3", "CALU", "CAMK1", "CANT1", "CASK", "CBX1", "CBX3", "CBX4", "CCNB1", "CD109", "CD276", "CD320", "CD47", "CDH2", "CERS2", "CHM", "CHPF2", "CHST14", "CIRBP", "CLCN3", "CLCN7", "CLN5", "CLN6", "CLPP", "CLSTN3", "CNNM3", "CNNM4", "CNP", "COCH", "COLEC12", "COMT", "COPS5", "COX15", "CPD", "CPE", "CPT2", "CPVL", "CRAT", "CRK", "CRTAP", "CSGALNACT2", "CSNK2B", "CTBP2", "CTBS", "CTNNB1", "CTNND1", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CUTA", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYC1", "CYP51A1", "DAG1", "DDX3X", "DHCR24", "DHCR7", "DHFR", "DHTKD1", "DHX29", "DLG1", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC3", "DNASE2", "DOCK1", "DSC3", "DSG2", "DVL2", "ECE1", "EFCAB14", "EGFR", "EHD1", "EHD4", "EHMT1", "EHMT2", "EIF4B", "EIF4H", "EIF5", "ENPP1", "EPDR1", "EPHA2", "EPHA7", "EPHX2", "ERGIC3", "F11R", "FAF2", "FAM3C", "FAM49B", "FAT1", "FCGRT", "FECH", "FKBP14", "FLOT1", "FMR1", "FTL", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP2", "GAA", "GALE", "GALNS", "GALNT1", "GALNT2", "GALNT7", "GBA", "GBE1", "GDI1", "GDI2", "GGH", "GGT7", "GLA", "GLB1", "GLB1L2", "GLG1", "GLT8D1", "GM2A", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNS", "GOLPH3", "GOSR1", "GPAA1", "GPAM", "GPD2", "GRAMD1A", "GRB2", "GUSB", "HACD2", "HCCS", "HDAC1", "HDAC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIP1", "HIP1R", "HLA-A", "HLA-B", "HLA-C", "HMGB1", "HMGB2", "HMGB3", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HPS6", "HS2ST1", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSPA13", "ICMT", "IDH1", "IDH2", "IFIT5", "IFNGR1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2R", "IMPAD1", "INPP4A", "IQGAP3", "IRS4", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "JAK1", "KDM1B", "KHDRBS1", "KIDINS220", "KIF5B", "KIFAP3", "KIRREL1", "LAMB1", "LAMP1", "LARP1", "LDLR", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LLGL1", "LNPEP", "LRIG1", "LRIG2", "LRP1", "LRP2", "LRRC8A", "M6PR", "MAN1A1", "MAN2B1", "MANBA", "MANEA", "MATR3", "MBLAC2", "MCL1", "MCUB", "MEN1", "MFGE8", "MFSD10", "MFSD8", "MGAT2", "MICALL1", "MIF", "MINDY3", "MINPP1", "MMGT1", "MMS19", "MPP1", "MPP2", "MRC2", "MSH3", "MSH6", "MSMO1", "MTMR2", "MTMR4", "MTOR", "NAA40", "NAGLU", "NAPA", "NAPG", "NCAM1", "NCSTN", "NDC1", "NDUFA8", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS2", "NDUFS6", "NECTIN2", "NEDD4", "NEO1", "NEU1", "NID1", "NISCH", "NMD3", "NNT", "NOTCH2", "NPC1", "NPC2", "NR2F1", "NRDC", "NRP1", "NUCB2", "NUP62", "OCRL", "OGDH", "OSBPL1A", "OSBPL2", "OTUB1", "P3H1", "P3H4", "P4HA2", "PACSIN3", "PALD1", "PAM", "PANX1", "PARD3", "PCDH7", "PCNA", "PCYOX1", "PDCL3", "PDHA1", "PDHB", "PDIA3", "PDIA5", "PDK3", "PFDN4", "PFDN6", "PFN2", "PGRMC2", "PHF6", "PHF8", "PHIP", "PI4K2B", "PI4KB", "PIGU", "PIK3R2", "PJA2", "PLA2G15", "PLBD2", "PLCG2", "PLD3", "PLEKHA5", "PLXNA3", "POFUT2", 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0.3142214461904322 0.0001379453868809 1.9327312747144497e-06 5.335654576842958e-05 6.706147432458563e-05 0.0042432632735376 +Dysostosis multiplex 8 11 2.940296430808639 0.0032789838372377 3.983009708737864 7.990291262135922 0.4150973501220912 0.1595724105588133 1.65382835361071 1.246316090990369 1.8479195153421644 0.2123242141003258 1.515498479661672e-09 0.0001386921185947 1.0005180886251859e-11 5.467949305753937e-10 2.387079528550129e-07 +Abnormal urine carbohydrate level 5 15 2.932566873323946 0.0033617251554574 3.883495145631068 11.70631067961165 -0.1388020161424021 0.4168246977061866 1.9096127339504616 1.3287920569685254 1.2303643442685093 0.3136870898203888 0.0001047249995307 0.0003706576678266 2.684369985471731e-07 5.5308739194744206e-05 0.0022975467393054 +Cherry red spot of the macula 7 10 2.9204566686235265 0.0034951879888949 4.87621359223301 9.031553398058252 0.4125318500531191 0.1346012745180574 1.6566187440434876 0.4477283705000042 2.101542046986786 0.2228325403979826 1.1751133467130894e-10 9.21605913978827e-12 2.61274849283924e-14 4.671491811739887e-11 1.1973446501175916e-08 +Hallucinations 15 54 2.909616444011297 0.0036187255550816 11.20388349514563 45.44660194174757 0.6705549628539956 0.4221278622600144 3.902598644570227 4.462852401771342 1.2595119979903464 0.3693437289960082 7.838205326676336e-05 0.0001225586688048 4.713898248248131e-05 2.7482625988568255e-05 2.238068645174709e-05 +Parkinsonism 11 38 2.8803568818360845 0.0039722525102712 7.453883495145631 30.097087378640776 0.7249761134976155 0.4663275088289313 3.116711838694066 3.708464636913605 0.8967824567735009 0.3291722600978801 0.0022260140860041 0.0085356676981486 0.0013942522830003 0.0010737250984011 0.0008487557347717 +Abnormality of the vasculature of the eye 14 82 2.8541092564975794 0.0043157686099919 16.27912621359223 72.06553398058253 0.403343228775578 0.4479390001832676 5.629952078086087 5.671259209870798 1.3806507490937323 0.3789287537753926 0.0013433257260153 1.3209633213208054e-05 2.485850157795612e-07 0.0004117693797608 0.0510841384257808 +Gait ataxia 16 83 2.8519535003656973 0.0043451456324867 14.351941747572816 68.35194174757281 0.6787136514518399 0.4783255809544575 5.256980668043156 6.678826209042067 1.046898326537344 0.3693668840587258 0.0005344863343956 0.0012291705571561 0.0001815482559421 0.0006430379383039 0.0026385709663193 +Aplasia hypoplasia involving the vertebral column 7 20 2.839461613742423 0.004518973178023 4.679611650485437 14.847087378640778 0.8883735186508074 0.3527358077962234 2.3127489306396716 2.051146083169333 0.9597872998017484 0.2871451112966173 0.0001379453868809 0.0187248462666395 0.0007430351028178 6.706147432458563e-05 0.0009279050553949 +Disproportionate short stature 11 31 2.818752154356956 0.0048210727797055 8.58252427184466 24.70145631067961 1.4449047806081987 0.2464238748623315 3.3320283680556178 3.793287097673045 1.0910515137563812 0.2952991105687103 0.0102887576342285 0.0704839558103872 0.0540767090111314 0.0056146507740375 0.0036803591594937 +Abnormal tissue metabolite concentration 6 16 2.808549278200863 0.0049765265525245 5.895631067961165 14.650485436893204 0.4799987914691458 0.2340469593783387 2.3926019349714145 2.328417679576543 1.7567023743300048 0.2768423789344761 0.0002229574617941 4.9441120883675e-07 1.4194050004739812e-05 0.0001189444497952 0.0008544422426654 +Ectopic calcification 23 67 2.80030622773677 0.0051054148770597 13.553398058252426 56.53155339805825 0.5275931647443897 0.4410566614950294 4.995100814049753 5.994858194438004 1.2985638579898735 0.3743313818119885 0.0001847286858347 0.0357664341382327 0.0029739112206691 5.797491380707032e-05 9.306547053303652e-05 +Abnormal circulating cholesterol concentration 11 34 2.799290378005641 0.0051215057849924 9.691747572815531 31.70873786407767 0.976903841313624 0.2790879029908041 4.4525142732793395 3.04459115485426 1.5883623188049951 0.3063455707490317 0.004074968927174 0.0521335433076176 0.005792379744814 0.0021480935661603 0.0002350502704126 +Mutism 8 21 2.7972873387433403 0.0051533679883313 3.779126213592233 15.25728155339806 0.1784571649104848 0.5864699912863285 2.1115151725422088 2.0281562693161783 0.804816156707226 0.2860634034809178 0.0002137935107596 0.0212633176973237 0.0096938597365547 0.0001047370599813 0.0003026550720459 +Hepatosplenomegaly 14 51 2.7880432576329426 0.0053027462663102 8.516990291262136 37.93689320388349 -0.2491143078233153 0.3795771447816016 3.305218390901912 4.60907695182212 1.4437156893960243 0.3360994118928947 3.98861078653288e-05 0.0010840000082347 2.94659283184057e-05 7.761159476096404e-05 3.650193587573659e-05 +Abnormal retinal vascular morphology 9 55 2.7824944231037616 0.0053942792376771 11.550970873786408 50.40291262135922 0.374132464893944 0.4137648703700375 4.646725961814426 4.349733979382428 1.4638612584769457 0.3720428539009304 0.0094200900244502 0.0001024786832624 1.7066691090873394e-05 0.0042928566226898 0.0731896741811078 +Neurodegeneration 8 33 2.7753821756215022 0.0055136873755086 6.381067961165049 28.4126213592233 0.4868261799791588 0.5776802355314765 3.0342592105069612 2.3821007132544736 0.7766560160165384 0.3229356835194168 0.0080863990245203 0.0402962873689797 0.0244837275894334 0.0046688430045599 0.0038884735347153 +Frontotemporal dementia 6 13 2.748251734994489 0.0059913989237503 3.4344660194174756 10.344660194174756 0.5931524822816645 0.4529040772840182 1.8896952177098856 1.3751065734754873 0.9402199282689112 0.308701646569884 0.0049092326538637 0.007105321595433 0.0001019966150707 0.0032545859437725 0.0001766322981222 +Urinary glycosaminoglycan excretion 6 9 2.740230416940049 0.0061396125491022 2.9490291262135924 6.563106796116505 0.4749855796693131 0.2196485727407601 1.2846457065606351 0.9261036754709504 1.6390629541794843 0.2603486997442626 5.276828574255545e-08 6.712740949068952e-07 3.152910227260874e-09 2.3855414605683373e-08 2.753445818664521e-06 +Mask like facies 7 16 2.7396576811017197 0.0061503205010238 2.837378640776699 11.854368932038836 0.2177832215347659 0.6585148050234894 2.3822280756056875 2.1071204618123236 0.6305099535731611 0.2584829668016643 0.3252287818061511 1.0 1.0 0.6508948194595567 0.0009279050553949 +Oculomotor apraxia 4 29 2.723475680326056 0.0064598971510883 5.648058252427185 24.56553398058253 0.4636956319177163 0.5717143314512599 2.6876056974482267 2.699887889853458 0.7708144058365661 0.3119126109104529 0.065415895023894 0.0069945898038035 0.0072681734443112 0.0437821029600269 0.3461731201018544 +Abnormal macrophage morphology 7 9 2.717769656079555 0.0065723575625693 2.9150485436893203 5.640776699029126 -0.1129741045260028 0.144980672561322 1.3090672390975422 1.117854819168669 1.9286041303300476 0.1913667515871486 2.779712548439352e-09 8.918029494024718e-07 5.005644754349108e-09 1.1168958688235491e-09 2.6189373825740344e-07 +Chronic diarrhea 6 22 2.716043995272436 0.006606713794345 4.514563106796117 18.550970873786408 0.2309588263877121 0.4319883908654413 2.0282666456418785 2.0703229027090826 1.177819281609388 0.3206617066576645 0.0084958408335642 0.0221396463904123 0.0102837000876808 0.0052710570752827 0.007013421835749 +Oligosacchariduria 5 7 2.7097935533829234 0.0067325098896313 2.4611650485436893 4.978155339805825 0.0914492290535993 0.2254706360721404 1.281286747781515 0.9537908500181173 1.6653598868357138 0.2594196870884814 9.976105319552485e-09 6.108202829893653e-06 1.8624041878153888e-11 4.993861717843809e-09 3.235576349203615e-07 +Coarse facial features 15 83 2.708923612690079 0.0067501879071873 14.893203883495143 65.1116504854369 -0.0571685725971772 0.580093215118004 6.012789962503995 6.952485076014798 1.0405087875423698 0.3452061173820699 2.2129911689207277e-05 0.0002055981747356 9.044558074410217e-07 5.210456566100677e-06 0.0021731476632859 +Arteriosclerosis 9 20 2.708411671044688 0.0067606105346911 4.885922330097087 14.944174757281552 0.0721468675738393 0.2032976413320727 1.852339343238996 2.0572604199467093 1.788928597657784 0.2405012300780825 3.838249264390716e-05 0.0016433207319013 9.137815410524424e-05 1.6783269894967037e-05 8.060398640515672e-05 +Cardiomegaly 10 41 2.7009272371165816 0.0069146464244733 8.490291262135923 34.762135922330096 0.0974375624133147 0.5220140632172088 3.5269287104729803 2.3403848536252574 1.0599377415868538 0.3263143509209658 0.0006031028652205 0.0008814481157451 0.0001940435749139 0.000259969323856 0.0033682884996015 +Fasciculations 10 43 2.696397893639185 0.007009388336314 9.201456310679612 36.5 0.4731561459207285 0.4826265043963199 3.4648999783170837 3.557775567723639 1.0532476984865673 0.3454376907067654 0.0005743189010032 2.2001184078103924e-05 5.3945309643300745e-05 0.00026590101721 0.000498263287066 +Platyspondyly 10 43 2.6941206778568114 0.0070574607032412 8.28640776699029 33.730582524271846 0.6662607465302498 0.4948187493576657 3.3732974430890796 4.074278380383408 0.9978722835718216 0.3450714604006198 0.0003902427630103 0.0623838765899965 0.0011889754911147 0.0001660347987942 0.0021102307461638 +Supranuclear gaze palsy 7 23 2.671387773962577 0.0075538326946416 5.186893203883495 19.1626213592233 0.8242716574954257 0.3183493558985887 2.2612229396433574 2.139608194404574 1.2188387108542005 0.2935859783151378 0.0005732293183858 0.000895633126088 0.0061250241039257 0.0003104448575285 0.000466746230466 +Progressive visual loss 5 31 2.670831346254332 0.0075663652895536 5.325242718446602 22.429611650485437 0.7316954387450431 0.34231947196034 2.467466703195611 2.985791083259841 1.255625436621734 0.3056268024259221 0.014841261642116 0.0056332205677222 0.0007060425621212 0.0087565646797269 0.0664525635950304 +Cerebral inclusion bodies 7 16 2.670127790829637 0.007582238373933 3.844660194174758 13.655339805825244 0.5051551663301821 0.4226246963159299 1.8115448621120656 1.6612796655742368 1.090041660052819 0.3107400387490911 0.0002229574617941 0.0005458668398673 0.0002651548018521 0.0001189444497952 0.000136080650842 +Neurofibrillary tangles 4 7 2.632084357175007 0.0084862789077579 1.9878345498783456 4.347931873479319 0.5966090900062281 0.2642083372508564 1.0995898071170882 1.1496807364853057 1.4348037417662018 0.2714513638042118 2.296556417175484e-05 3.8887516945815136e-05 7.461632952232611e-06 1.31526437712885e-05 0.0003637398802397 +Abnormality of glycolipid metabolism 5 8 2.618858239959169 0.0088224601953543 3.83495145631068 7.228155339805825 0.3163887308740252 0.1681411938672545 1.311614193945771 0.5964160722258837 1.870431483654663 0.2292796295173983 7.146414679684763e-08 5.713939408073963e-10 1.795667029584697e-08 3.59582749836129e-08 2.2319352116665367e-06 +Psychosis 8 35 2.617049067017704 0.0088693590784785 7.441747572815534 29.73543689320388 0.4742861565216377 0.5201326315543127 2.950893373754939 3.867389997355917 0.8779517344338251 0.3210463988305211 0.004074968927174 0.0058478787222266 0.005792379744814 0.0021480935661603 0.009987232196926 +Diminished motivation 9 31 2.615097341760216 0.0089202029237052 6.317961165048544 24.803398058252423 -0.1022353224236823 0.6108539410275737 2.662827119874009 2.347832734733778 0.8069717348682304 0.2991361798929995 0.0008196932585148 0.0026953565990113 0.0021465314893355 0.0004129808075874 0.0003597488401456 +Increased bone mineral density 8 31 2.614077250441151 0.0089468804891501 6.242718446601942 24.75 1.1480702818250033 0.3148175930983396 2.4533156459354677 2.2345749579547443 1.0849696139569316 0.312718333498069 0.0001994521022297 0.0533785743764077 0.000797605257637 8.331817056305445e-05 0.010858973261353 +Abnormality of the pharynx 18 60 2.612207668871376 0.0089959590680335 10.41504854368932 47.383495145631066 0.067596841044417 0.5761817636058506 4.885590736267591 6.0273260761814775 0.9974162330328638 0.3381496724546956 0.0034278545878901 0.0004796443034186 0.0002964582202175 0.0051017818302581 0.005370450483445 +Blindness 18 95 2.6010272673430985 0.0092945066056555 17.50485436893204 77.9878640776699 0.5531690923808372 0.4517712920686044 6.330499123572238 7.312865926515748 1.2869313794328858 0.374312554297374 7.261378449830316e-06 0.0003984546477083 0.012227438591947 6.123153232512559e-06 0.0006414687526187 +Optic disc pallor 14 58 2.5831570954647103 0.0097900733416329 14.480582524271844 48.592233009708735 1.02733963234224 0.3801436604957769 5.692535706296588 6.181615230530596 1.3595924408188145 0.3692839687174071 0.0001032085097961 0.4502911936035841 0.0290362076287452 3.395831158812935e-05 0.0002326758474062 +Abnormal autonomic nervous system physiology 14 39 2.579702255052952 0.0098885533359907 8.24757281553398 32.320388349514566 0.4638475540870246 0.4509985093876737 3.0051523606495087 3.6502788621576223 1.089960321271389 0.3249871136051702 0.0009976695712008 0.0060673937801388 0.0060698672163979 0.0023184274251433 0.0010151666938761 +Abnormality of the gingiva 10 54 2.5738848996754755 0.0100563721760669 9.87621359223301 46.04126213592233 0.4066177797442131 0.5493526186039737 4.388501882181702 4.364546747363985 0.9993836878157942 0.3390641087927739 0.0022551848386165 0.163845303256872 8.52056703139056e-05 0.0008981179696018 0.0273282549246303 +Abnormal oral mucosa morphology 11 70 2.568860738124476 0.0102033452392533 12.099514563106796 58.75485436893204 0.3909737086326091 0.6033731457854445 5.163567269709676 5.859238885605998 0.9283175157401292 0.3479637416005023 0.0057364870110308 0.2406407895411775 0.0004887438098738 0.0022732435342592 0.0802035942554187 +Abnormal pharynx morphology 10 49 2.56697088067805 0.0102591227278492 8.514563106796116 37.03398058252427 0.1877670148504528 0.5274660382080113 3.853164322289049 5.032786743682863 1.0570894568249165 0.3376598170825433 0.0008937375663291 0.0002089603767857 9.714238185978128e-05 0.0015161779380161 0.0078899167162162 +Visual loss 11 61 2.557954435428773 0.010528988718208 12.189320388349516 49.779126213592235 0.7709512625515322 0.4025114627500821 4.5744204921606055 5.175300864908489 1.242827263568942 0.3662286004483653 0.0010722986739546 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bodies 4 10 2.537115895675337 0.0111769945457822 2.6237864077669903 7.359223300970874 0.2693483252678329 0.2925663833748981 1.3659227234427256 1.183251804829311 1.455225024558189 0.2873440473038876 0.0001997614514391 2.8801476738141424e-06 4.236608354872846e-05 0.0001164002838048 0.0027898710574492 +Rigidity 13 64 2.524623207626201 0.0115822397185239 11.191747572815531 54.36893203883495 0.6876310756020901 0.5027192484685672 4.377749328022216 5.9336792418276065 0.9658030249698788 0.360069708832764 0.0021864033902029 0.023691411776477 0.033005107755267 0.0009247476459738 0.0030779590389499 +Abnormal larynx physiology 4 17 2.506274973355763 0.0122010693085885 3.7694174757281553 14.78640776699029 0.7777362681295714 0.3936810823701626 2.010346212391085 1.51625807571557 0.9784109402665334 0.3028779878197117 0.072793602414709 0.0133509861907553 0.0466281418945222 0.0552623668853733 0.0285239329034339 +Exaggerated startle response 3 9 2.503952921301174 0.0122814374999478 2.987864077669903 8.699029126213592 0.0610274034602423 0.2634753902852135 1.4337635656228835 1.0620090089420118 1.617556501702403 0.2831541938798349 0.0005664524138943 6.712740949068952e-07 1.0100053103379697e-05 0.000366006536683 0.0048470794580564 +Dysmetria 18 68 2.4974291402783355 0.0125097464020922 14.618932038834952 55.148058252427184 0.6447099310037795 0.5301040823699991 5.464619727151339 6.3203263646610806 0.9326090127326924 0.3593910006397782 0.0071501500871056 0.0003613299844351 0.0002029723759345 0.0111927939680839 0.0079447116047884 +Hyperintensity of cerebral white matter on mri 6 22 2.494507107986711 0.0126132200233397 5.844660194174757 19.76456310679612 0.5239793769920946 0.3497882694217939 2.383223245915457 2.1845455756818453 1.3844482033830876 0.3203944687906004 0.0001854924478643 6.575020599903326e-05 0.0008840144918394 9.063996119237736e-05 0.0054986690042778 +Disproportionate short limb short stature 9 24 2.4892575037097866 0.012801021211412 6.587378640776699 19.902912621359224 1.344701363676014 0.2682000023842777 2.8599402401133336 3.1206003999939886 0.9439707190715964 0.2973700803613334 0.0366493043441931 1.0 0.4825947600252522 0.0238750792658836 0.0052752857705798 +Retinal detachment 6 21 2.4841475756730653 0.0129861978415091 3.941747572815534 14.580097087378642 0.5369031517500233 0.5057677956850462 2.153458463438811 2.8955761353524423 0.8356573249695263 0.3047965741525345 0.0023355066279001 1.0 0.1388614812827933 0.0238750792658836 0.0456420212494776 +Foam cells 5 7 2.483719497742929 0.0130018178242301 2.9611650485436893 5.398058252427185 -0.064606162326146 0.1366553329191208 1.1817572081322671 0.893230265545378 1.9405286208577948 0.1862104272675829 9.976105319552485e-09 6.108202829893653e-06 5.454643878372586e-07 4.993861717843809e-09 4.612828059530947e-09 +Abnormal circulating lipid concentration 19 82 2.4816687859249216 0.013076876240307 21.0995145631068 75.44417475728156 1.321442689138656 0.3287247628796158 8.33534407984455 6.5596064623065375 1.4065018349702674 0.365722219395451 0.002584052897251 0.0526657559172975 0.0254451356639491 0.0009767971219441 0.0002617532931736 +Hepatic failure 13 53 2.480005867164391 0.0131380220874819 12.25242718446602 48.050970873786405 0.7424989852941342 0.3814651163177168 5.527018274076851 5.448329576476532 1.3577793424610205 0.3539023729255708 0.0017409997133428 0.3958501174260305 0.2569300433589926 0.0007782063417519 0.0003831802786428 +Progressive psychomotor deterioration 3 9 2.4711687418692425 0.0134672255523815 3.349514563106796 8.320388349514563 0.5379615244672443 0.2176134167318772 1.5053866894387542 0.6226094824456632 1.5848775742530583 0.2457660654605461 0.0002190470461162 2.3666612945957126e-05 0.0001778916397324 0.0001405335592956 0.0019736987849612 +Abnormal conjunctiva morphology 6 31 2.4676484682425666 0.0136003808170339 6.997572815533981 26.58495145631068 0.5265054436970301 0.4429378103171669 2.669041123051977 2.4927208099742058 1.133049116684961 0.3300379664677785 0.0144047655175133 0.0111951113174208 0.0002948437912435 0.007976907507528 0.1767689055566925 +Purpura 10 28 2.4616064607903123 0.0138316341274944 5.058252427184466 20.5 0.2949204348840655 0.5870295511534446 2.439860105485306 2.9167244562004924 0.8045540309438518 0.3066000737873682 0.0016401471153886 1.0 0.4620800234731917 0.0008410935227018 0.0009315989296259 +Coarse hair 5 22 2.4598498097250228 0.0138995169004985 4.686893203883495 18.616504854368937 0.2343700701412837 0.5417146669091575 2.329949176130645 1.927954652781107 0.8671729178541636 0.2932988727143946 0.0242634305165485 0.0171096007657598 0.0588586045542952 0.0166437437365411 0.0133292154466835 +Dysgraphia 3 18 2.457779197137825 0.0139799097267059 3.888349514563106 14.1747572815534 -0.020954539630261 0.7180644151789357 2.573607681679318 1.633551045654117 0.6042658996811474 0.2627585792299407 0.0283612865760576 0.0187248462666395 0.0007430351028178 0.0195417527514502 0.1534735865665994 +Abnormal large intestine physiology 8 28 2.446264348300926 0.0144345123293692 5.104368932038835 20.50242718446602 0.3008286810865617 0.501154789704215 2.3382177969194613 2.943232146467361 0.9913296101531662 0.3267316971730095 0.0377232249045742 0.0221396463904123 0.0748026769138462 0.0262238710799836 6.665492380594059e-05 +Delusions 5 21 2.445397914836384 0.0144692404294859 5.912621359223301 18.439320388349515 1.0629964764413025 0.2985925736346436 2.390745896997379 2.2281751696560335 1.2165016471530676 0.297036724651636 0.002338672529899 0.1583124314184509 0.0443091130960601 0.0014099836558107 0.0061413176576109 +Osteoarthritis 5 12 2.444760110696736 0.0144948517455474 3.783980582524272 10.466019417475728 1.011181157871384 0.2141266987491498 1.7388858389175554 1.4384831140913243 1.3548711699904423 0.2434324139099127 8.496955950432245e-05 1.0 0.2372212797486779 4.476197901851534e-05 0.0018986041281287 +Abnormality of skull ossification 6 19 2.441681659257186 0.014619031287004 4.366504854368932 12.970873786407768 1.1881205011944458 0.2637442069575459 1.99249670608582 1.4511884027191762 0.8848235988748787 0.2626440236811827 0.0002646566168432 0.1541506060207377 0.0420348553288257 0.0001415457384854 0.0010317596261269 +Personality changes 3 17 2.4293869660132312 0.0151243801556473 4.235436893203883 16.20873786407767 0.716641708966708 0.4361664780008399 2.2513009299259603 2.2727002372019856 0.9467269936740988 0.3182188186141179 0.0827445671958278 0.1706778675257841 0.0513963234576887 0.0630731351339203 0.1102038070082231 +Chorioretinal dysplasia 3 7 2.425881148027643 0.0152712705577748 1.7402912621359223 5.298543689320389 0.7805003547346996 0.372123736539573 1.2140072106043596 1.250513609252692 0.912363976173464 0.2760281930947573 0.002185329286291 1.0 1.0 0.0133829456596615 0.0168879338153791 +Abnormal neuron morphology 8 32 2.410905377855036 0.0159129762791092 6.186893203883495 28.24514563106796 0.6484714329574719 0.4735595458743487 3.2896606279139218 2.2567268866496706 0.9337112301481814 0.3347227917865519 0.1120369345362934 0.0437266531990119 0.0275216398495969 0.0814773755217055 0.0052752857705798 +Periventricular white matter hyperintensities 3 10 2.409722321427324 0.0159646660063632 2.978155339805826 8.604368932038835 0.7206271937008832 0.2495118997135797 1.313488091366194 1.3113693798075805 1.4898193087366574 0.2872267653893681 0.0005664524138943 4.844157765872774e-05 0.0003602808960722 0.000366006536683 0.0048470794580564 +Abnormal chorioretinal morphology 7 31 2.402169216913145 0.0162981672050379 8.45631067961165 26.4004854368932 0.7945769566543296 0.4616483000942599 3.6317817687878136 4.493501214243663 0.9878512993647718 0.3399479614013815 0.0832455196554392 1.0 0.6629984443692342 0.1339560302608873 0.1756395820329416 +Muscle stiffness 5 24 2.40027896670943 0.0163825813742817 5.109223300970874 19.216019417475728 1.2530133657268057 0.2695837776665858 2.5817154639007844 2.4582801786037667 1.0397164239726309 0.2961148999712332 0.0611564659396009 0.237457799625543 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exteroceptive sensation 14 65 2.387906149251056 0.0169446682635838 10.759708737864075 52.02427184466019 0.4941713240335635 0.5557419524937993 3.9194595318694754 5.696566262954939 0.9102536370390476 0.3437672640084617 0.0131605356098593 0.00056713534557 0.0108150411126969 0.0064629825009123 0.0029570945788725 +Elevated pulmonary artery pressure 8 31 2.3844856978581883 0.0171030127970135 7.422330097087379 24.033980582524272 0.8771466934674594 0.3206437689207037 3.083196929894625 3.78086786662344 1.283632173810104 0.3146045769490745 0.0102887576342285 0.3555919235953944 0.2107495506364678 0.0056146507740375 0.0280093810648813 +Petechiae 6 15 2.381113584954758 0.0172603889154716 3.371359223300971 10.71116504854369 -0.1851490078975502 0.5536256491282784 2.0242354656692445 1.6299894579269991 0.8286264243882893 0.2753873949251904 0.0003122463304368 1.0 0.2872333566147377 0.000167417985794 0.0012367549633919 +Respiratory failure 13 76 2.3778873334265533 0.0174121451747388 15.308252427184469 64.92233009708738 0.6334303745407566 0.5052857133990365 5.520010364276267 5.289556151454055 0.9962199001839442 0.3695677120431103 0.0011978941128597 0.0010126126886353 0.0041049904908562 0.0015307386537109 0.0210911576003047 +Generalized muscle weakness 7 38 2.37213427288456 0.0176856622767096 7.728155339805825 32.1626213592233 0.5657235813512097 0.5484647799965952 3.662839300714657 2.6485498729392836 0.8197648550400668 0.3335986274065884 0.1002935753267686 0.0732573258319426 0.2178091494673695 0.1770898669719441 0.0733486282159671 +Thickened ribs 4 5 2.367555214042363 0.0179060480199302 2.1966019417475726 3.883495145631068 0.1570596970089875 0.2019197615503783 1.062461013240685 0.4837348803243926 1.726961229131412 0.2439172689185779 2.816833245233132e-07 3.8308667598491466e-06 2.747580602519606e-07 1.5853493324517234e-07 5.068595405713639e-06 +Astrocytosis 1 8 2.359529784043259 0.0182981119494467 1.7888349514563109 6.650485436893204 0.2566372779470236 0.4739812199291527 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2.1310679611650487 7.259708737864078 0.3527899633564624 0.3302362894597835 1.2627239108344035 1.5017879029535528 1.2692310088213898 0.2695913026312082 0.0011910371662417 0.0847528009868792 0.0006327439593496 0.0007750266814789 0.0096830476876922 +Decreased facial expression 11 39 2.29976189113072 0.0214617135756094 6.735436893203883 28.148058252427184 0.2149999362982568 0.7077005747378508 3.697992968299203 4.372233784743368 0.6043567156688953 0.2824472326805742 0.0538501803344362 1.0 1.0 0.0940079969551786 0.003161967003339 +Diffuse cerebral atrophy 7 22 2.2979247636359244 0.0215660715880205 4.320388349514563 16.526699029126213 0.5483679808262946 0.4347204443631116 2.152955035100649 2.40585163991881 0.9855175878314706 0.3059596216572743 0.0680331793156344 0.012648542478749 0.0443091130960601 0.051542815486873 0.0002117782770131 +Vertical supranuclear gaze palsy 4 15 2.2955043156591017 0.0217042393715032 3.279126213592233 10.99271844660194 -0.1470543995224959 0.5219545433760947 1.9908165894446412 1.9389831656938616 0.9427069653541744 0.3045918405911866 0.0014768241824232 0.0038211367015083 0.014058804472369 0.000963248429344 0.0017273216459823 +Macroglossia 7 39 2.295057912251236 0.0217298056447581 8.597087378640778 33.800970873786405 0.2378332400826553 0.526108686434358 3.4819634097071916 3.0993577519995683 1.045257905641647 0.335668429128709 0.0063569839269134 0.0135596849536518 0.0029560859975957 0.0115780683173507 0.0586628611190371 +Abnormal cerebral artery morphology 3 19 2.292673635031796 0.0218668015268754 3.6893203883495143 15.189320388349516 0.1461288400266414 0.5737075812512653 2.321403685727363 2.2061437876789474 0.9153426901574684 0.3191805767887729 0.0429933331736 0.0239365913087713 0.0115248505447769 0.0300192966842153 0.2122136175080588 +Hypoplasia of the odontoid process 3 10 2.2868408916426906 0.0222051117289645 1.7135922330097086 5.849514563106796 0.7084033927132167 0.339821590839337 1.2308769108438145 1.328066978835538 1.0561070911915744 0.2674195088010785 0.0009463420108467 0.0030581061915538 0.0005309775927247 0.0006143549700213 0.0078256896811826 +Neuronal loss in central nervous system 5 15 2.2861916503750144 0.0222430490288292 4.087378640776699 12.526699029126211 0.982175765643533 0.2959736314179056 1.731247914675439 1.993135251988059 1.1236470294677874 0.2967990988512021 0.0082698135769466 0.1373006943976843 0.2518545844225215 0.0055331858379351 0.0136556200878641 +Submucous cleft of soft and hard palate 7 30 2.283666221780197 0.0223911546558641 5.138349514563107 22.941747572815533 0.8980380147163236 0.4007892874523231 2.272201189765468 2.581958475140233 0.7850752745431548 0.2945527466716488 0.0002773777473486 1.0 0.456826794009695 0.0007645401995723 0.0106544274266035 +Dyslexia 3 12 2.281774443842929 0.0225026603423821 2.1601941747572817 7.475728155339806 0.2166553391739945 0.5515562047031062 1.638009673491431 1.806647166536097 0.83073289390057 0.2841643517290823 0.0181910910024147 0.0981765691424607 0.0170518298819148 0.0133829456596615 0.0168879338153791 +Avascular necrosis 7 25 2.279293153847849 0.0226496447314614 5.070388349514563 21.203883495145632 0.6420454351604097 0.3947374085674277 2.2614105153836106 2.2592172512550373 1.1319127818663337 0.3183649666305153 0.0008196932585148 1.0 0.1039407380726692 0.0004129808075874 0.0058484491569579 +Perseveration 3 9 2.2760816691940557 0.0228411219987487 2.228155339805826 7.747572815533981 0.2549642857282638 0.5145676770156781 1.6269524477167985 1.327223882767772 0.9406545169811942 0.3029494680332692 0.0100699756610546 0.0030581061915538 0.0005309775927247 0.0073447144383531 0.0078256896811826 +Anophthalmia 4 15 2.268673663991855 0.0232881782895104 2.861650485436894 9.395631067961164 0.4842375076047043 0.4992513937830266 1.7811813452413223 2.297377217063272 0.8357915391858239 0.2927718406240587 0.0161902722620554 1.0 1.0 0.0432632841258681 0.1264250298394598 +Bone pain 7 27 2.2686284608908385 0.023290929347379 4.975728155339806 22.203883495145632 0.6350188771758896 0.4127751797545932 2.519707411717398 2.310210444333206 1.0375367125895096 0.3016728005813124 8.01909948424294e-05 0.027703186905031 0.0142561824639166 3.5525803469399624e-05 0.0037131193455902 +Abnormal metatarsal morphology 10 31 2.262691278555823 0.0236547268279772 6.706310679611651 24.638349514563107 0.7721346669926398 0.4611221801551243 2.9696946625730853 3.9478131090337834 0.8523308608564429 0.3258568187536518 0.0075430554991159 1.0 0.2676422850845579 0.013435076878633 0.0306656162818578 +Mucosal telangiectasiae 2 11 2.2589717948394337 0.0238851394131232 3.2354368932038833 9.689320388349516 0.8501086222195428 0.291727970426265 1.410916714116348 1.5996305775803197 1.2598794700933909 0.2907637890882055 0.0390334633726749 0.0082126449787597 0.0023694947377154 0.0291459656321865 0.151991389222775 +Echolalia 4 13 2.2584911662229983 0.0239150546995337 2.9174757281553396 9.798543689320388 0.5058827478481593 0.4925214398455364 1.939118365602947 1.8645121737734769 0.8858392104742214 0.309610151743164 0.0128645943328501 0.1541506060207377 0.0420348553288257 0.0086864012748381 0.0227729863487681 +Truncal ataxia 3 20 2.2540205144695347 0.0241948774387792 4.774271844660194 17.15776699029126 -0.3012313781599291 0.6222678380840454 3.359527562122923 1.658125876233355 0.666012913564146 0.2730518053572522 0.032846548252385 0.0204019662414969 0.0693457394610891 0.0227330174276438 0.1723337140806459 +Abnormality of pulmonary circulation 8 36 2.2416911813393536 0.0249813382309775 8.439320388349515 28.538834951456312 0.8940347945025898 0.342085103264471 3.349932259027002 4.295622811850572 1.233599840087162 0.3264185554851845 0.0259376357179921 0.410668613679594 0.2747845331601694 0.0147861479784934 0.0746496231499551 +Diffuse white matter abnormalities 6 13 2.237166595914988 0.0252754536969272 2.9514563106796117 8.87135922330097 0.5952845668725205 0.3852144131329246 1.9847899342355348 1.8774220853320651 1.0510828155917642 0.2960660984241839 0.1555278412167982 0.1201219647894398 0.2223047329091382 0.4704807306772423 0.0349002560689848 +Inappropriate behavior 4 22 2.229428563939972 0.0257854034630851 4.111650485436893 16.885922330097088 0.1384539200488892 0.5568708768969491 2.346689507546719 2.02390948073287 0.8632293435648196 0.2961880037432384 0.005255517230189 0.0011134897140002 0.0006788789579845 0.0032221742646108 0.0149334923888548 +Abnormal morphology of the abdominal musculature 3 13 2.224603123366524 0.0261078927849482 2.5194174757281553 9.696601941747574 0.2129739773830804 0.6038296710628059 1.594015400665463 1.8242402612786552 0.6929182513306914 0.2584919547665449 0.0986900198440846 0.1828652209005429 0.327507803675052 0.0756846958642696 0.135456568067581 +Abnormal visual fixation 2 8 2.224174221561289 0.026136724736326 2.1237864077669903 6.516990291262136 0.3282606812074232 0.2644845064785266 1.2333226229346623 1.2136771814929264 1.4687997702265556 0.2650474123539905 0.0118457633601407 0.0034296220851759 0.0126574737404708 0.0086586519898169 0.053660443290246 +Gingival overgrowth 5 32 2.222543337218979 0.0262466086679216 6.575242718446602 27.825242718446603 0.1204797749519533 0.5977288845661025 2.9954121374406206 2.6918690387294624 0.8787295676695109 0.30503252385188 0.026095084493996 0.3394178268581344 0.0012547267698553 0.0157664629434176 0.0501354544324543 +Memory impairment 6 47 2.220453523801273 0.0263879972204614 9.20631067961165 37.271844660194176 0.6455055455031676 0.5315679983039603 3.950378988895289 4.419054449573657 0.8352402457141732 0.3415020574881957 0.0177304532753077 0.0125141686160449 0.0025963332517443 0.0099144414072724 0.0502245614271679 +Slurred speech 4 13 2.2141864446728947 0.0268159559552283 2.45873786407767 8.864077669902912 0.5323927403653204 0.4147809462031548 1.4075891250208603 1.616351781434359 0.9973486618272436 0.2852319096618858 0.0390334633726749 0.1287528218161406 0.0293903981750984 0.0291459656321865 0.0101939997718642 +Abnormal lactate dehydrogenase level 6 20 2.212280318855314 0.0269473021216606 4.143203883495145 17.87621359223301 -0.1889046507521062 0.4455642582293665 2.002759607594022 2.089436499733168 1.1284322896017482 0.2992123479577444 0.0002808348072404 0.2106238865633207 0.371655018795122 0.0057706709278987 0.0078773866774108 +Young adult onset 4 12 2.2094277939146085 0.0271448995876568 3.936893203883495 11.097087378640778 0.9326277418903632 0.2839315553797075 1.7793033594374144 1.2484130750505644 1.1998221427979727 0.2831359733121 0.0546538468970855 0.1457663642848915 0.266209970857853 0.0411512789917762 0.0178313437064756 +Weak voice 3 8 2.2086165803373627 0.0272013211057413 1.550970873786408 5.737864077669903 0.4344739918343515 0.5015398770888346 1.4038172747545303 1.1779624093475138 0.8128091354527174 0.2801301484192541 0.0137899394557154 1.0 1.0 0.0101015401572799 0.0118045746321095 +Abnormal vascular physiology 12 60 2.2063359970723746 0.0273604827332751 12.74757281553398 50.021844660194176 0.816183607478715 0.4136638745601454 4.907827009322534 5.622165606934028 1.2216480011219424 0.371091913776798 0.0441085464714825 0.0519267383076168 0.083711718614366 0.0234945424705507 0.0743632569415555 +Increased circulating antibody level 3 20 2.192599251439073 0.0283362651123788 3.2402912621359223 15.145631067961164 0.5908116743587006 0.4340890712285613 1.9578142936372311 2.533878285328643 0.9673694377645128 0.2975830104493745 0.0578861973095776 0.2336798458054532 0.0149914480702132 0.0408612650970917 0.2651421429497402 +Abnormal muscle fiber morphology 17 81 2.1853552414605506 0.0288628099246088 17.78640776699029 68.04126213592232 1.263675841483234 0.3649599499596623 6.500784844979595 6.6307423444197315 1.1691802531751734 0.3853191125649093 0.0004223922310201 0.1866334965042685 0.2016492336575425 0.0017794509470607 0.0007829566585339 +Frontotemporal cerebral atrophy 1 6 2.184785281619092 0.0289045937193723 1.635922330097087 3.6699029126213594 -0.3624350132713084 0.5330027825600345 1.0420624032272796 1.0510129142469402 0.8971727321188119 0.2957465021303376 0.0402937008043179 0.0573151884822011 0.0056684159955205 0.032628233248221 0.1121927202905578 +Psychomotor deterioration 3 10 2.18224547507637 0.0290914207369632 3.2645631067961167 8.910194174757281 0.9753014938956188 0.1960965459818884 1.3866235282600423 0.7031088807706056 1.4929387846379636 0.2609606457365817 0.0045876876261238 3.066034551708988e-05 0.0002296483500821 0.0033170374819039 0.0027426851014433 +Abnormal femoral neck head morphology 12 59 2.174618423255944 0.0296587225747331 11.097087378640778 44.88834951456311 0.710356821644891 0.4647128189516342 4.081724752298962 5.521112188696193 0.9531654138623804 0.3489729073692786 0.002318014151652 0.0241824215416069 0.0074800485008838 0.0009829630455582 0.0084731831587988 +Orthostatic hypotension 5 17 2.1686196900344386 0.0301115690455215 3.6262135922330097 14.315533980582524 0.2234754096973065 0.4106322335953559 1.878879089774009 1.367959097892007 1.1506876393484995 0.291561214686976 0.0064450358458905 0.0082126449787597 0.0293903981750984 0.0042924995678 0.0018986041281287 +Abnormal biliary tract morphology 5 26 2.1631748843509744 0.0305277312192637 7.427184466019417 23.174757281553397 1.329418499193971 0.249884151345828 2.8924137189053876 2.044064029481889 1.3393824039546371 0.2984385007787948 0.0139480443947214 0.2298835505782255 0.0919415891551245 0.0385372375494843 0.0419925752917376 +Abnormality of the ribs 14 77 2.1612689025757543 0.0306745736287976 15.46359223300971 63.26456310679612 0.6596881680500318 0.4822792711086646 5.162987649103379 7.327989071924885 1.0464354559452582 0.3722680363619953 0.0228856301409007 0.0174923714516836 0.0465553733545724 0.0105257079774322 0.0204942464503499 +Abnormal aortic valve physiology 7 45 2.157840623162092 0.0309402252724648 8.133495145631068 38.407766990291265 0.3164235083362472 0.5832127363016096 3.634936253961654 4.470913316924635 0.8570668738614753 0.3290269262839486 0.0121079316044836 0.4308176920885813 0.0968104322956701 0.0062659657814626 0.187701763239854 +Central scotoma 5 9 2.1570116504038466 0.0310047566950975 3.657766990291262 9.152912621359222 1.2790732929494344 0.2261272578521709 2.0233738200365714 2.077016218281829 1.2675536526802949 0.279373459017325 0.0355418461382186 0.1244478155008913 0.2297987482657219 0.0264830942684438 0.0394546172777071 +Abnormality of the odontoid process 3 11 2.1535907040954654 0.0312722839189845 1.8883495145631068 6.849514563106796 0.4809480703698225 0.3910181029813887 1.283638712356007 1.328066978835538 1.0241378212028085 0.2619757585976807 0.0018071258891623 0.0042324529563037 0.0008717411361388 0.0011814468070448 0.0142025885279179 +Fatigable weakness of swallowing muscles 3 15 2.150279362462618 0.0315331238233409 3.604368932038835 13.28640776699029 0.7350730209032469 0.4315977104446384 2.070664341544873 1.3796403459639466 0.8910590288568366 0.3148309196851129 0.1944778963944218 0.1373006943976843 0.2518545844225215 0.1627514901813832 0.0550493127109652 +Hyperorality 2 6 2.13887584775823 0.0324457245739524 1.6310679611650485 4.002427184466019 0.1778776820278384 0.5939018161480435 1.1574183798699982 1.1309820168189242 0.887997457397679 0.3243733441031166 0.0341781603031309 0.0526645480715484 0.0047533286028597 0.0276231155809849 0.0139360561882317 +Decerebrate rigidity 2 5 2.1341997088714644 0.0328264365345689 2.070388349514563 4.286407766990291 0.7483196612133007 0.2095871679116443 0.9590634816350864 0.5578301484347907 1.4826535249517825 0.245070013535738 0.0003693662950738 0.0003491251705821 0.0013376518177504 0.0002629541815867 0.0020257428393968 +Abnormal rib cage morphology 18 96 2.1336409203748112 0.032872185619059 17.694174757281555 75.7135922330097 0.5488633555797945 0.5379800174608891 5.594611229067785 9.71314341791714 0.9782995531616954 0.3690468558866111 0.0036751953895875 0.0349846041813154 0.0108655402102264 0.0032863265424334 0.0112427287168037 +Enlarged thorax 7 23 2.132784208800073 0.0329424322355202 3.851941747572816 16.553398058252426 0.6878502324489157 0.4991384851328346 1.9804680030663864 2.795551790331099 0.7693523377829645 0.315559863824272 0.0129096423068016 1.0 0.0890100643743446 0.0362911702166911 0.105877285302659 +Abnormality of femur morphology 17 85 2.1304918027491446 0.033131031854839 17.20873786407767 66.68203883495146 0.8363246416857221 0.4265359075043799 5.791282481104246 7.777760660479065 1.2398669594969238 0.3848538433547022 0.0002630622446822 0.0025628275436732 0.0026814473363835 7.371600505420815e-05 0.0028869008119388 +Abnormal form of the vertebral bodies 20 105 2.127725779014986 0.0333598262459484 19.968446601941743 83.88349514563107 0.6644002102675167 0.5345165392282933 7.187939907318809 8.37593753149639 0.9881357365384656 0.3722270618536288 0.0003717102727934 0.0320324193550872 0.0024873657620093 9.40212177100631e-05 0.0018977525389104 +Abnormal lower motor neuron morphology 2 10 2.1241230038727226 0.0336598594030141 2.1771844660194173 8.701456310679612 0.8468629004048428 0.2893246976958152 1.3759952567341256 1.207057649999096 1.1584035743641086 0.2695692447215745 0.0290684739516603 0.0065792573185243 0.0016986126979642 0.0215683584236732 0.0306674579519183 +Abnormality of lysosomal metabolism 3 6 2.1227691654283056 0.0337731998854438 2.0509708737864076 4.776699029126213 0.6001877831871685 0.2139165882109918 1.054267347463803 0.832379194243084 1.5763659100060583 0.2506311014666729 0.0014601836592373 0.0008300469730069 0.0031504918831051 0.0010464818333657 0.0005644670723367 +Abnormal tongue morphology 17 82 2.117173572526449 0.0342451194176576 16.939320388349515 69.1116504854369 0.4277424777250148 0.5766387697572775 5.679438944349523 6.766002978496539 0.9505300446189564 0.3567930620053219 0.014001811778823 0.0881349697343571 0.0173196391401033 0.015126255227887 0.0167055381352979 +Agnosia 3 11 2.1170558716938666 0.0342551062490468 2.3179611650485437 7.589805825242719 0.1757316253762871 0.5950456373149905 1.6818181673434287 1.4411406489524723 0.8023652176956552 0.2951625920182743 0.0355418461382186 0.1244478155008913 0.0021303683071518 0.0264830942684438 0.0394546172777071 +Epiphyseal stippling 5 14 2.1112772727164426 0.0347484863477183 4.638349514563107 12.094660194174756 1.0555865796987824 0.32401635996293 2.3050778042540805 1.737163917644219 0.9677864882437331 0.2966156619887163 0.0426927090881441 1.0 0.031373049189738 0.0319451393300601 0.0022975467393054 +Abnormality of the wrist 9 41 2.1087524082191207 0.0349659585260591 6.95873786407767 30.155339805825243 0.4893391061224179 0.4739542714047036 3.2628753712893035 4.83666675230799 1.0000289125440789 0.3174741185520122 0.0044143107565969 0.0115168854492305 0.0648989212296417 0.002183892978537 0.017564228185315 +Abnormal ilium morphology 6 25 2.1071604342254964 0.0351036752574838 4.495145631067961 19.194174757281555 0.0329470365043978 0.5619634224264741 2.2806649788563607 3.271109940265621 0.838909695425034 0.2834205972308914 0.034691382732658 0.0425713267043903 0.0264876267470493 0.0225481074784796 0.0426420036932981 +Abnormal macular morphology 6 34 2.105859246791254 0.0352165805754374 5.881067961165049 26.936893203883496 0.2429090782086877 0.4668963917414836 3.102290232183583 2.9305717090684964 1.1278643921545293 0.335754410396833 0.0271192479728592 0.0981576694070633 0.0201115001422002 0.0154968415322929 0.1526117820256423 +Recurrent aspiration pneumonia 1 6 2.098789419239512 0.035835467966744 2.0606796116504853 6.25 0.3948833569251968 0.2988616259147967 1.2222482563963537 0.6632700690261994 1.354266830500057 0.2888538147928982 0.0682786800017594 0.0756950383436983 0.1432798584585485 0.0557098434243155 0.1801322612125274 +Skeletal muscle hypertrophy 8 52 2.095106624105695 0.0361615152314034 9.978155339805824 43.95873786407767 0.2882267398053342 0.5822719825831179 4.164926192558732 4.192080647433412 0.9226697759716594 0.3424177343120818 0.0095836533755535 0.0267203622241427 0.0087667818001301 0.0145245063124035 0.1070674378709577 +Scotoma 6 12 2.0935292359384388 0.0363019370527086 4.189320388349515 12.196601941747574 1.1271039056750725 0.2779036999445621 2.1128553643245884 2.0698220238662226 1.1901076059375446 0.2884356618441315 0.0223579622998359 0.1788224008957527 0.0563311776114605 0.0153023562212604 0.0425821240391988 +Abnormality of the spleen 31 146 2.0926355946332165 0.03638169658258 25.813106796116504 118.70145631067962 0.3588217969137363 0.458825127767632 7.787937091054707 11.816587724549532 1.4144879662363967 0.3705037351683085 2.4372942722327546e-07 4.211680676254738e-05 3.0105395499674894e-08 2.990207068606094e-07 3.334037931141858e-05 +Emg chronic denervation signs 4 17 2.091671599066506 0.0364679027857375 4.550970873786408 13.815533980582524 0.6176194543661773 0.3415909714455588 2.199917039284479 1.6085184210885628 1.2249413291120588 0.2985007469873863 0.0260894037169127 0.0060718409625537 0.0219975904219434 0.0193169154759243 0.0051689545539866 +Pectus carinatum 10 45 2.09154054487074 0.0364796358588457 7.939320388349515 34.36893203883495 -0.0141334573494885 0.6532036142688402 3.536042920854893 4.0953212500379435 0.7176636635375233 0.2900192214992909 0.0860306269033879 0.4279811411777856 0.023308813864781 0.0555655068618841 0.0970573207370123 +Hydrocephalus 22 94 2.088308862580174 0.0367699825201457 17.5 74.83009708737865 0.4864280032519437 0.6085787069163106 5.8879092832817435 9.478912056611868 0.8088784016382273 0.3500416531762792 0.0097570121755097 1.0 0.1349728642419889 0.0084326106677622 0.0100332270354643 +Progressive gait ataxia 6 15 2.085968235180487 0.0369815005080997 3.3810679611650487 11.0873786407767 0.9190295749650902 0.2658532875386696 1.7592835107251577 1.880439920211323 1.2434873962438642 0.2734996669217905 0.0232832774509756 0.0055832614279084 0.0202898922491691 0.0172025832638257 0.0042587077964903 +Abnormal mitral valve physiology 7 44 2.085172423833736 0.0370536520814956 9.37621359223301 38.37864077669903 0.2302649184785056 0.5746059188976989 3.903784227411165 4.570093803830835 0.8587145467195402 0.3157753352621624 0.0115194470383602 0.4279811411777856 0.0948939281427919 0.0059466548235716 0.0970573207370123 +Venous insufficiency 3 7 2.073771917844795 0.0381004983954751 1.5631067961165048 5.660194174757281 0.5118223066706069 0.4552197834062824 1.2379116686073368 1.1621322724229128 0.9295972263181714 0.3009174121939262 0.5367207092530247 1.0 1.0 0.4957890007184933 0.0443313868612348 +Bilateral tonic clonic seizure with generalized onset 4 12 2.0724899075862537 0.0382197764812306 2.628640776699029 9.150485436893204 0.3549735330824753 0.3751938453615744 1.486330954367188 1.3992628979412365 1.186094318222537 0.303082450755102 0.0546538468970855 0.1457663642848915 0.266209970857853 0.0411512789917762 0.0178313437064756 +Arthritis 11 50 2.0723926304334666 0.0382288400812247 10.45631067961165 41.12864077669903 0.9299077951686036 0.3844403642845474 3.7326340917241647 4.351147052994631 1.200139433310656 0.3557501916131977 0.0006721814254858 0.0981576694070633 0.0855550276988868 0.001172923761026 0.0006904985122567 +Infantile axial hypotonia 3 11 2.0638624151309566 0.0390307631978339 3.0970873786407767 9.91747572815534 0.2141703344813526 0.3664899290512883 1.6385203075306134 1.5973234399272347 1.21609252960959 0.2741067096589152 0.0082698135769466 0.0093923264669034 0.0028960612595367 0.0055331858379351 0.0550493127109652 +Abnormal csf protein level 6 15 2.0635071573411143 0.0390644684916157 4.434466019417476 12.20631067961165 1.1239853500963992 0.2260559983233297 2.11400242863219 2.084072511592451 1.241935948510828 0.248039542652958 0.0205468999708647 0.1747599807978781 0.3143397790261298 0.0140312853386763 0.1183710372220029 +Pulmonary infiltrates 3 10 2.0630499901731847 0.0391078788705046 2.203883495145631 7.41747572815534 0.5937593446740285 0.3342650103364393 1.20966354385806 1.2445943063002318 1.1896790379366604 0.2811562889912624 0.0049092326538637 0.007105321595433 0.0255840399150975 0.0032545859437725 0.0349002560689848 +Schizophrenia 5 23 2.059842982781858 0.0394135539591551 5.444174757281553 19.50242718446602 0.9817145874838714 0.3473822480141803 2.400301366302062 2.641618717487706 1.084663392230114 0.3211478296747099 0.004732381298193 0.1828652209005429 0.327507803675052 0.0028945217060241 0.0032176405980257 +Cortical cataract 1 5 2.0593642644213013 0.0394593564092786 0.779126213592233 2.716019417475728 0.6503747459082428 0.4226548474861212 0.7289114197599987 0.7628737693566847 1.132679355556404 0.3141002405724725 0.0101908497095879 1.0 1.0 0.0081566962170519 0.0308595287001273 +Amyotrophic lateral sclerosis 5 18 2.059020741912916 0.0394922515325137 4.453883495145631 16.203883495145632 1.0855969203541704 0.3037117925086244 2.3812188822255287 1.5445439412417563 1.0118111691913367 0.2917679915833991 0.3051705239844653 0.1828652209005429 0.327507803675052 0.260178364686727 0.0133292154466835 +Motor neuron atrophy 6 25 2.0574767378485497 0.0396403902913393 5.410194174757281 22.424757281553397 0.8356342611289532 0.3959768073616548 2.754377444710008 1.6813276911909307 0.954775311801755 0.3176984078794489 0.1528462583582923 0.0248568883498602 0.0832345551471358 0.1193188519501932 0.0098371476265694 +Retinal dysplasia 3 9 2.0546148242781306 0.0399162226768836 2.6990291262135924 7.878640776699029 0.934970332417222 0.3353928049199215 1.4834684590696818 1.182325377441881 0.8740525348763903 0.2730031671079428 0.0030987261931693 1.0 1.0 0.0172025832638257 0.0231565450655555 +Aplasia hypoplasia involving the femoral head and neck 2 11 2.051850700437977 0.0401841742512312 2.8737864077669903 9.281553398058252 0.635457346844393 0.478164837571615 1.7882008729852883 1.6961834699269718 0.8140555353638919 0.3095034219133895 0.0355418461382186 0.1244478155008913 0.2297987482657219 0.0264830942684438 0.1404563889721742 +Vertebral compression fracture 4 17 2.050222527771828 0.0403427206055115 3.718446601941748 15.771844660194176 0.638605685637545 0.4585378455721924 1.8270750975800616 1.3728941491613926 0.8197174983565503 0.2921971535023096 0.0049092326538637 1.0 0.2223047329091382 0.0032545859437725 0.0073870683046854 +Apraxia 22 77 2.0475269741142 0.040606371179763 13.12378640776699 63.390776699029125 0.1814768045276288 0.7502130658452598 5.1129682099093285 6.458997816596385 0.5555009903042052 0.2766393571109705 0.1322284509252497 0.0627348303600114 0.0333379855708233 0.0811724962206102 0.0676379149618881 +Abnormal urine cytology 8 43 2.0452934282994857 0.0408259382197599 7.905339805825243 38.74029126213592 0.1397968004380557 0.6345678609070249 4.377598604797632 3.4861762947224593 0.775500557033054 0.3063073533495467 0.0236810750719008 0.4047844567784328 0.2676422850845579 0.013435076878633 0.0679633918851584 +Aplasia hypoplasia of the abdominal wall musculature 2 8 2.042945994310624 0.0410577845473183 1.980582524271845 5.084951456310679 -0.2941172899595095 0.5946501672510873 1.308898466133281 1.375961004884913 0.7739483548600558 0.293628893230155 0.1651267208209027 0.1244478155008913 0.2297987482657219 0.1374615323876937 0.1404563889721742 +Ecchymosis 4 15 2.04215041414791 0.0411366133747752 3.150485436893204 12.45388349514563 0.354738604817978 0.5388105616424155 1.8595528111766295 1.4846494359247462 0.8259851254358525 0.2959005364929857 0.0073200005110444 1.0 1.0 0.0048864602536943 0.0118390941536887 +Bowing of the legs 14 70 2.035546120250175 0.0417959528661544 11.155339805825244 51.15533980582524 0.3696320760225168 0.6089630438985444 4.432902753984072 6.8301264136382995 0.7679030342482581 0.32405716235975 0.0007593006022583 0.1673171702489807 0.0562914471207365 0.0010032469319 0.0060557627340503 +Abnormal visual electrophysiology 6 57 2.0318651856291257 0.0421673058496974 11.310679611650484 49.08009708737864 0.5738496712827478 0.4298926605512212 5.601714588788375 4.822166856762376 1.2686017151039417 0.3684491475281102 0.0959747855317885 0.005312366512423 0.0498119439040731 0.0596487583268479 0.3976395249721389 +Hypoplastic vertebral bodies 2 6 2.031501932591808 0.0422041036947937 1.9757281553398056 5.771844660194175 0.8508946908089206 0.2775138956505893 1.1057630163966317 0.6800795892498206 1.1536023105486033 0.2559235656158802 0.0467857032007149 0.0619434524836269 0.1180585699575878 0.0379575415698398 0.0224777557227792 +Progressive spastic quadriplegia 3 10 2.0255639816465782 0.0428094856796308 2.6407766990291264 8.094660194174757 0.8041722661618813 0.2980182786117089 1.3079619433616207 1.0302561803519357 1.23715789109981 0.2930725496255146 0.0020444031671849 0.0010343090391069 0.0039135152062846 0.0014684283121974 0.0009048869233579 +High myopia 3 12 2.0225659819970434 0.0431179144244289 2.2572815533980584 8.861650485436893 0.2147355078038008 0.6195168366607675 1.7492912263297076 1.0940195744573682 0.7003066081324636 0.2683857668661165 0.1846138683178138 1.0 0.2445730022705269 0.154226710893935 0.0495301536946375 +Rhizomelia 7 14 2.022405685852435 0.043134458154538 4.276699029126213 11.868932038834952 1.3783619481702345 0.228956695884812 2.09278482575067 1.6655579622091714 0.936017394236602 0.2616202806826952 0.7178145582619702 1.0 0.3593428278464597 0.6756630435254583 0.0702989298923652 +Fatigable weakness of bulbar muscles 3 17 2.022288751689884 0.0431465299958429 4.063106796116505 15.25242718446602 0.7188062683419271 0.4547422847838221 2.248170358195387 1.4859761696395852 0.8778510505210118 0.3261836450387849 0.3152159885961936 0.1868885334554594 0.3339976348230559 0.2691814013824262 0.1443540625367929 +Abnormal saccadic eye movements 4 28 2.0163844392260413 0.0437597913906262 6.293689320388349 24.570388349514563 0.6352395547829492 0.4765898942028741 2.9458970942458165 3.3125821982342476 0.9514629694011908 0.3397171221111555 0.1120369345362934 0.0437266531990119 0.1388614812827933 0.0814773755217055 0.2326921082564013 +Diminished movement 5 25 2.015810438280081 0.0438198016353166 4.735436893203883 20.063106796116504 0.4187250068129663 0.566255912993213 2.471273118969614 2.6913918978509783 0.7869950723241854 0.3067708672830038 0.0084958408335642 0.2067156970649581 0.3655284832956332 0.0052710570752827 0.0249814119485349 +Abnormal epiphyseal ossification 8 20 2.015778830565895 0.0438231081539186 6.451456310679611 16.274271844660195 1.1227269321938518 0.3276999393402902 3.140724178369711 2.4155680760400804 1.043634905787503 0.3148370578580727 0.1157633766244994 1.0 0.0666692325567911 0.0893115916137597 0.0185344065780108 +Xerostomia 4 17 2.014814207698212 0.0439241198133706 4.225728155339806 15.218446601941748 0.9400183964262208 0.3676147626670514 2.1144482637513415 1.4041718405623504 0.8665256443899695 0.3037909474394171 0.2647856458513017 0.1665759675679584 0.3009165941166509 0.224257489169728 0.1023001003732698 +Skin nodule 6 24 2.0132580010040715 0.0440874942581859 6.070388349514563 21.26456310679612 0.7442674094202993 0.3924071478475022 2.7239314899251803 2.029014432281319 1.0984628042075235 0.3129154853478004 0.0275174215549463 0.0380696669646128 0.0225654450263633 0.0177220872628324 0.0319321530393264 +Glomerulopathy 2 11 2.007530632791274 0.0446931922838977 2.820388349514563 9.96359223300971 0.665958332940798 0.3017859836474246 1.512655943869742 0.8764085521210618 1.2285906000166364 0.2785070215881056 0.0232832774509756 0.1070183553885475 0.0202898922491691 0.0172025832638257 0.097693310147501 +Partial agenesis of the corpus callosum 3 17 2.005597449145039 0.0448992142869162 2.4805825242718447 12.37621359223301 0.3108447892877026 0.5867231295875102 2.2827150523400936 2.0376831582479853 0.7780915839539295 0.2858898371625797 0.0680331793156344 1.0 0.0045096021611559 0.051542815486873 0.0873197005539923 +Zonular cataract 7 16 2.004181740355299 0.0450505958189213 3.04126213592233 10.71359223300971 0.6482844736848132 0.4757859716104625 1.6665604248665455 1.9447488940504751 0.8413866153147622 0.3111450918700563 0.0260894037169127 1.0 1.0 0.0193169154759243 0.0051689545539866 +Abnormality of visual evoked potentials 3 25 2.002819335424753 0.0451966837088135 5.912621359223301 21.344660194174757 0.5310511795384435 0.4083718861321034 3.290488782756552 2.4160960308239137 1.1796429833196167 0.3304773196682204 0.0283612865760576 0.0187248462666395 0.0640285846884502 0.0195417527514502 0.1534735865665994 +Abnormal atrioventricular valve physiology 9 57 2.002121455819157 0.0452716704616307 12.565533980582524 48.907766990291265 0.1539939838390574 0.5936441921951698 4.945634188898197 6.03840764260975 0.8374402616515446 0.3148683063707032 0.0034278545878901 0.4847391385004878 0.1382318498722026 0.0014801972688608 0.0603470940684236 +Coxa valga 7 30 1.9981688715421544 0.0456983550852678 5.245145631067961 19.95145631067961 0.3761170106319844 0.4485543113651226 2.6522752145550523 3.395824508532713 1.0354006500412785 0.2987185055269495 0.0016401471153886 0.0391768542263283 0.003280625197885 0.0008410935227018 0.0116770517604269 +Joint stiffness 11 64 1.9937290974463968 0.0461816677090356 12.87864077669903 55.95873786407767 0.3271163739047257 0.5669766886577318 5.4865086159860095 5.123309227065953 0.9871597951660472 0.3442632187865738 0.0095836533755535 0.0267203622241427 0.0087667818001301 0.0046244173507252 0.0115431866149959 +Postural tremor 5 17 1.9874677515641008 0.0468705861431073 5.194174757281553 17.851941747572816 1.214872214945056 0.2487017685351703 2.341305968762478 2.2981463861426747 1.2391489410765593 0.2821199379659175 0.0932441718455508 0.1788224008957527 0.0563311776114605 0.0713646261968556 0.0118494727859131 +Abnormality of epiphysis morphology 15 72 1.98203064772984 0.0474758105983814 14.885922330097088 57.24757281553398 0.6699051414631522 0.4959188251133739 5.664066249559964 8.729587504130462 1.029966158611096 0.3689041276003297 0.0348344973051326 0.2406407895411775 0.1117702104379008 0.0173731870668378 0.0443848884975187 +Retinal degeneration 10 69 1.9779662668038187 0.047932512292075 11.890776699029129 56.16747572815534 0.249024006789609 0.518990175786131 4.729602333356375 6.268553853518324 1.1275766261124216 0.3578686327011649 0.0142386678763481 0.0138043868231735 0.0098834190825323 0.0168074693834496 0.1321941507178679 +Emg myopathic abnormalities 8 36 1.97208279703876 0.048600155454729 7.839805825242719 28.910194174757283 0.2098150446047547 0.690965565053031 3.403819664995595 3.954743122654069 0.667845981128364 0.2949850800118646 0.0599411916866013 0.0559003563721154 0.1724639155075248 0.1191496891129861 0.0127721185030957 +Genu valgum 11 48 1.9716610427311605 0.0486483136905908 7.601941747572815 33.84708737864078 0.2260078974275034 0.6018037651922443 3.228633441491814 4.874982326294667 0.7872516244202112 0.3080168567591513 0.0006721814254858 0.0981576694070633 0.0201115001422002 0.001172923761026 0.0059260433388042 +Dyscalculia 4 14 1.967703513898971 0.0491021612933726 3.2985436893203883 10.41504854368932 0.0956671530576073 0.5921414769301718 1.859297762710788 1.6561350337670822 0.8138112872585297 0.2933304152976729 0.1184088205118859 0.1026081339138497 0.018640880521655 0.097689242801984 0.0034687949642114 +Beaking of vertebral bodies 2 13 1.967137888435219 0.0491673162715902 2.907766990291262 9.131067961165048 0.3586161575708288 0.4129848752927794 1.656478269216378 1.797329687366794 1.1037549452259698 0.2913355105961067 0.0159045536144147 0.0937235599037543 0.0008717411361388 0.0116756742779249 0.0698565063333662 +Emg neuropathic changes 6 31 1.962774392785078 0.0496723945225159 6.915048543689321 24.58252427184466 0.5887299592537784 0.4208819793990807 3.046574831105746 2.544837804909062 1.1306803597402475 0.3318248802653038 0.032846548252385 0.0013622028220488 0.0091243340822671 0.0227330174276438 0.0054986690042778 +Abnormality of the upper respiratory tract 31 121 1.9615597548616996 0.0498137616596319 19.66504854368932 95.80582524271844 0.4534569687157453 0.5959175600884278 6.924659870205313 10.36312380503997 0.9632839800839448 0.3651113920771414 0.0011389225124152 0.0005539910228347 0.0001215305722018 0.0008229450121982 0.0024023338387582 +Hypercholesterolemia 3 13 1.9609808284936927 0.0498812593517945 2.8519417475728157 12.00728155339806 -0.1529343230707107 0.3623594582363142 1.842044325627787 1.2666159287719958 1.267359005945563 0.2788890099190976 0.0242634305165485 1.0 0.327507803675052 0.0166437437365411 0.135456568067581 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5de17bb21f446a4e3a487ff857b68b74210dfba1 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 4715, + "title": "Average number of proteins per term", + "value": 27.230116648992578 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8f02d667002d06928c2e48e912ad20a8e908386d --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..092f41f4432a5ba663d1ad4c78d4ac0f1e11a0ac --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1649 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Dementia 0.7179451512748003 4.077945488436384 4.54354153678338e-05 0.192839584466672 0.2142279834593411 69 Q04446,Q13501,P27544,Q9Y287,Q9NWW5,P04062,P07602,Q9Y487,P05067,P17900,Q9UBX1,P15289,P06865,P61916,Q13510,Q92673,Q14108,Q9NQ11,P02792,P31483,Q9NUM4,P35637,O00592,Q06787,O15118 25 +Mental deterioration 0.683367798296115 3.5321040743421532 0.0004122670672939 0.8569040683439303 0.4782575625826351 111 Q9BQE5,Q04446,Q13501,P27544,Q9Y287,Q9NWW5,P04062,P22626,P07602,Q9Y487,P05067,P17900,Q9UBX1,O75503,P16278,P50897,P54802,P15289,P06865,P61916,Q13510,P07686,Q92673,P10644,Q14108,Q9NQ11,P02792,P31483,Q9NUM4,P21964,Q9H2C2,P35637,O00592,Q06787,O15118,Q8NHS3 36 +Loss of speech 0.8237487679434514 3.312852093769901 0.0009234980369883 0.9871743098145128 0.4782575625826351 23 O00754,P50897,Q9NUM4,Q13501,P61916,P07602,P17900,O15118 8 +Splenomegaly 0.6441982499897498 3.273226311336496 0.0010632730703032 0.9933690002082148 0.4782575625826351 105 P14174,P01889,P15260,Q16625,Q15904,P04062,P07602,P15586,P16278,P54802,P61916,Q13510,P10253,Q96J02,P08236,P38571,P11166,Q14108,P51798,Q86WC4,P51688,Q15392,P21964,P04066,Q99519,Q04721,O00754,O15118 28 +Juvenile onset 0.6844445968412931 3.1817680222759614 0.001463790120755 0.9989990710156668 0.4782575625826351 48 O14773,P16278,P34059,P54802,P41440,Q13510,Q04656,O15118,P06280,P50402,P38571,P51798,Q9NQ11,Q8NHS3 14 +Abnormality of head blood vessel 0.7660737366665784 3.178792788976249 0.0014788977220585 0.999067987217031 0.4782575625826351 28 P01130,P16278,P10619,P06865,Q13510,P07686,P07602,P17900 8 +Abnormal retinal artery morphology 0.7888454544776492 3.1575376181095436 0.0015910770640765 0.9994512693017362 0.4782575625826351 24 P16278,P10619,P06865,Q13510,P07686,P07602,P17900 7 +Abnormality of extrapyramidal motor function 0.58917927631562 2.9919985101124924 0.0027715761572828 0.9999979261931164 0.4782575625826351 90 Q04446,Q13501,Q6DKK2,P04062,P07602,P05067,Q9H6K4,P17900,Q9UBX1,P16278,P06865,P07686,Q92673,P11166,Q9NQ11,P02792,Q9NUM4,O75787,Q15043,P35637,O00592,Q06787 22 +Corneal opacity 0.5928604075752079 2.979037301828219 0.0028915557480131 0.9999988240505716 0.4782575625826351 67 O43505,Q9P273,Q16625,P04062,Q14118,P06280,P16278,P34059,O75845,Q13510,P08236,Q06136,P10619,P01130,Q9Y5Y5,O75844,P04066,Q99519,P53701,O00754,P34913,Q9H9S5 22 +Diarrhea 0.5862240437680216 2.964995286742371 0.0030268756695488 0.9999993798855792 0.4782575625826351 90 P01889,P15260,Q15904,P00533,P06280,P15586,P17301,P54802,Q13510,P07686,Q96J02,P38571,P51688,Q08J23,Q13423,P02786,P42892,O00592,Q93100,Q6YHK3 20 +Limb ataxia 0.7229863333708515 2.964900409780953 0.0030278093058535 0.9999993826176348 0.4782575625826351 29 O14773,Q8IV08,O00754,Q13501,Q9BUK6,P04062,Q14108 7 +Clumsiness 0.7590106765285124 2.9599195427188874 0.0030771939493439 0.9999995112129044 0.4782575625826351 23 O14773,O00754,P31483,P15289,Q13501,Q13510,P07602,O75503 8 +Ascites 0.676254308891737 2.950869065127721 0.0031688121643926 0.9999996830976056 0.4782575625826351 35 P61916,Q13510,P04062,P10644,P08236,Q14108,O15118,Q86WC4,Q99519 9 +Progressive neurologic deterioration 0.7694788672112337 2.9493365633712765 0.0031845696086958 0.9999997058585708 0.4782575625826351 22 P16278,P54802,Q9Y287,P04062,P07686,P07602 6 +Dysostosis multiplex 0.9385862604762316 2.940296430808639 0.0032789838372377 0.9999998118095872 0.4782575625826351 11 O00754,P16278,P54802,P08236,P15586,P10619,P04066,Q99519 8 +Abnormal urine carbohydrate level 0.853791230020714 2.932566873323946 0.0033617251554574 0.9999998727658236 0.4782575625826351 15 P16278,O00462,P10253,P04066,Q99519 5 +Cherry red spot of the macula 0.9562823608227228 2.9204566686235265 0.0034951879888949 0.9999999323337748 0.4782575625826351 10 P16278,P10619,P06865,Q13510,P07686,P07602,P17900 7 +Hallucinations 0.6304869900463098 2.909616444011297 0.0036187255550816 0.9999999622861164 0.4782575625826351 54 P35637,Q9BQE5,O00754,P50897,P15289,Q6DKK2,Q13501,P21964,O00592,P04062,Q92673,P07602,P05067,Q9NQ11,O75503 15 +Parkinsonism 0.6617107338887167 2.8803568818360845 0.0039722525102712 0.9999999929233688 0.4782575625826351 38 P35637,P02792,Q9NUM4,Q13501,O75787,P04062,Q92673,Q15043,P07602,P05067,Q9NQ11 11 +Abnormality of the vasculature of the eye 0.5613128986906322 2.8541092564975794 0.0043157686099919 0.9999999986085036 0.4782575625826351 82 P16278,P10619,P04439,P06865,Q13510,O00462,P07686,P02786,Q9HCM3,P07602,P06280,P17900,P04066,Q99519 14 +Gait ataxia 0.5627071348788433 2.8519535003656973 0.0043451456324867 0.9999999987892204 0.4782575625826351 83 O14773,Q8IV08,O00754,Q9NUM4,P15289,Q13501,O00592,Q06787,P07602,Q9NQ11,P41440,Q92581,Q14108,O15118,Q05086,P98155 16 +Aplasia hypoplasia involving the vertebral column 0.7722956943357734 2.839461613742423 0.004518973178023 0.9999999994684622 0.4782575625826351 20 Q04721,P16278,P34059,O95831,P10644,P08236,P04066 7 +Disproportionate short stature 0.685690771129855 2.818752154356956 0.0048210727797055 0.999999999872936 0.4782575625826351 31 P16278,P34059,O75718,Q32P28,Q15392,Q8WVQ1,P10644,Q7LGA3,O00116,O94766,Q9UBM7 11 +Abnormal tissue metabolite concentration 0.8072903500171325 2.808549278200863 0.0049765265525245 0.999999999939168 0.4782575625826351 16 P15289,P06865,P07686,P07602,P06280,P17900 6 +Ectopic calcification 0.5722022673399154 2.80030622773677 0.0051054148770597 0.9999999999669728 0.4782575625826351 67 Q16625,O00584,P23786,P04062,Q14118,P05067,P53634,O75845,P10644,P38571,P08236,P11166,P29992,Q9UBM7,P01130,Q9Y5Y5,P22413,O00429,Q04656,O75844,O00116,Q9NPE3,Q99519 23 +Abnormal circulating cholesterol concentration 0.6612031802245536 2.7992903780056415 0.0051215057849924 0.9999999999693978 0.4782575625826351 34 P01130,Q15392,O75845,P61916,Q15904,Q8N511,Q15800,P07602,P34913,P50402,P38571 11 +Mutism 0.7533228688751548 2.7972873387433403 0.0051533679883313 0.9999999999736868 0.4782575625826351 21 Q9H9B1,P35637,P02792,Q9NUM4,Q13501,Q13510,Q92581,P53701 8 +Hepatosplenomegaly 0.6227366179736771 2.7880432576329426 0.0053027462663102 0.9999999999870376 0.4782575625826351 51 O00754,P16278,Q04446,P15260,Q13510,P23458,P04062,P07686,Q96J02,P38571,P11166,P10619,P51798,Q99519 14 +Abnormal retinal vascular morphology 0.6111433223493027 2.7824944231037616 0.0053942792376771 0.9999999999916008 0.4782575625826351 55 P16278,P10619,P04439,P06865,Q13510,P07686,P07602,P17900,Q99519 9 +Neurodegeneration 0.6649082484092288 2.7753821756215022 0.0055136873755086 0.9999999999952314 0.4782575625826351 33 P35637,P02792,Q92804,Q13501,Q68CQ7,P08236,P17900,Q8NHS3 8 +Frontotemporal dementia 0.8534042950558351 2.7482517349944895 0.0059913989237503 0.9999999999995052 0.4782575625826351 13 P35637,P31483,Q9NUM4,Q13501,Q92673,P05067 6 +Urinary glycosaminoglycan excretion 0.9335042740299224 2.740230416940049 0.0061396125491022 0.999999999999755 0.4782575625826351 9 P16278,P34059,P54802,P08236,P15586,P04066 6 +Mask like facies 0.7934068483061574 2.7396576811017193 0.0061503205010238 0.9999999999997672 0.4782575625826351 16 O75787,Q04656,P04062,Q06787,Q13049,Q9NQ11,Q9H9S5 7 +Oculomotor apraxia 0.6836260864971146 2.723475680326056 0.0064598971510883 0.9999999999999464 0.4782575625826351 29 O14773,Q92673,Q13501,P05067 4 +Abnormal macrophage morphology 0.9279860178745366 2.717769656079555 0.0065723575625693 0.9999999999999686 0.4782575625826351 9 P16278,P61916,P15260,Q13510,O15118,Q86WC4,Q99519 7 +Chronic diarrhea 0.7273991261790704 2.7160439952724356 0.006606713794345 0.9999999999999732 0.4782575625826351 22 Q08J23,Q15904,Q13510,P07686,Q96J02,P02786 6 +Oligosacchariduria 0.967627329988289 2.7097935533829234 0.0067325098896313 0.9999999999999852 0.4782575625826351 7 P16278,O00462,P10253,P04066,Q99519 5 +Coarse facial features 0.5474694177968127 2.708923612690079 0.0067501879071873 0.9999999999999865 0.4782575625826351 83 Q9H9B1,O00754,Q04721,P16278,P34059,P51688,P54802,P07686,Q7LGA3,P06280,P15586,P08236,P10619,P04066,Q99519 15 +Arteriosclerosis 0.7478335311902031 2.7084116710446877 0.0067606105346911 0.9999999999999872 0.4782575625826351 20 P01130,P16278,P61916,Q13510,O75844,P34913,P38571,O15118,Q99519 9 +Cardiomegaly 0.6314150007092122 2.7009272371165816 0.0069146464244733 0.9999999999999938 0.4782575625826351 41 P54802,Q07021,P23786,P10253,P04062,P13473,P07686,P10644,P04066,Q99519 10 +Fasciculations 0.6274729689875531 2.6963978936391855 0.007009388336314 0.999999999999996 0.4782575625826351 43 P35637,Q9NUM4,O95831,Q13501,Q13510,P51114,P22626,P07686,P07602,P06280 10 +Platyspondyly 0.6271574514295077 2.6941206778568114 0.0070574607032412 0.9999999999999968 0.4782575625826351 43 O00754,P16278,P34059,Q32P28,Q8WVQ1,O95831,Q04656,P08236,P48735,P04066 10 +Supranuclear gaze palsy 0.7082042238462081 2.671387773962577 0.0075538326946416 0.9999999999999996 0.4782575625826351 23 P02792,Q13501,P61916,O15118,P04062,P07602,Q9NQ11 7 +Progressive visual loss 0.6625643634476852 2.6708313462543316 0.0075663652895536 0.9999999999999996 0.4782575625826351 31 O14773,P50897,O75503,P98164,Q99519 5 +Cerebral inclusion bodies 0.7795202486564994 2.670127790829637 0.007582238373933 0.9999999999999998 0.4782575625826351 16 P31483,P61916,Q9Y287,P04062,Q92673,P05067,O15118 7 +Neurofibrillary tangles 0.9478011947097174 2.632084357175007 0.0084862789077579 1.0 0.4782575625826351 7 P05067,P61916,Q92673,Q9Y287 4 +Abnormality of glycolipid metabolism 0.9241416949513398 2.618858239959169 0.0088224601953543 1.0 0.4782575625826351 8 P06865,P07686,P07602,P06280,P17900 5 +Psychosis 0.6270207712325062 2.617049067017704 0.0088693590784785 1.0 0.4782575625826351 35 P02792,Q9NUM4,Q13501,P61916,Q9Y287,O15118,P10644,Q9NQ11 8 +Diminished motivation 0.6539608992550074 2.6150973417602157 0.0089202029237052 1.0 0.4782575625826351 31 Q9H9B1,P35637,Q9NUM4,P06865,Q13501,O00592,P04062,P17900,Q9NQ11 9 +Increased bone mineral density 0.6538039882507485 2.614077250441151 0.0089468804891501 1.0 0.4782575625826351 31 P51688,P54802,Q15392,Q13501,P51798,P04062,Q14108,Q86WC4 8 +Abnormality of the pharynx 0.574980633990635 2.6122076688713753 0.0089959590680335 1.0 0.4782575625826351 60 P16278,P34059,P51688,P54802,P01889,Q03519,Q7RTS9,P21964,Q86YV9,Q13510,O15460,P13051,O00192,P00533,P15586,P08236,Q15833,Q10469 18 +Blindness 0.5549995365760354 2.6010272673430985 0.0092945066056555 1.0 0.4782575625826351 95 P16278,O43505,P50897,P01889,P06865,Q9H6K4,O43676,Q5SZK8,P07686,Q9HCM3,P07602,O96000,Q6YHK3,Q9H9S5,P17900,P51798,Q8NHS3,P53701 18 +Optic disc pallor 0.5775503918137102 2.5831570954647103 0.0097900733416329 1.0 0.4782575625826351 58 O00754,P04439,O95831,Q9BUK6,O43676,Q9Y287,O14936,Q9HCM3,O96000,Q8NHS3,Q6P4Q7,Q9H6K4,P51798,Q86WC4 14 +Abnormal autonomic nervous system physiology 0.6172368617868755 2.5797022550529514 0.0098885533359907 1.0 0.4782575625826351 39 P42892,Q04446,P15289,Q04656,O00592,P04062,P07686,Q9H270,P07602,P06280,Q06787,P41440,P0DP25,Q6PJG6 14 +Abnormality of the gingiva 0.5874464266727186 2.5738848996754755 0.0100563721760669 1.0 0.4782575625826351 54 O00754,P16278,P53634,Q15392,P10644,P04062,P08236,Q14108,Q86WC4,Q99519 10 +Abnormal oral mucosa morphology 0.5346273226721652 2.5688607381244757 0.0102033452392533 1.0 0.4782575625826351 70 O00754,P16278,P53634,P01889,Q15392,P10644,P04062,P08236,Q14108,Q86WC4,Q99519 11 +Abnormal pharynx morphology 0.5983815079651551 2.56697088067805 0.0102591227278492 1.0 0.4782575625826351 49 P16278,P34059,P51688,P54802,P01889,Q13510,P13051,P00533,P15586,P08236 10 +Visual loss 0.5653750502406003 2.557954435428773 0.010528988718208 1.0 0.4782575625826351 61 O14773,P04439,P50897,P01889,Q9HCM3,P07602,Q8NHS3,P51798,O75503,P98164,Q99519 11 +Macular purpura 0.7294338050022664 2.554571553878279 0.0106318574978996 1.0 0.4782575625826351 19 Q16625,Q8NCH0,P10644,P04062,Q6YHK3,P51798,Q99519 7 +Dysdiadochokinesis 0.7478235490137533 2.5537884719995896 0.0106557969611738 1.0 0.4782575625826351 17 Q13501,Q9BUK6,Q06787,P41440,O75503,P98155 6 +Action tremor 0.5546463189047415 2.5505555237960778 0.0107551391011606 1.0 0.4782575625826351 64 P35637,O14773,P15289,Q9NUM4,O75787,Q9Y287,Q06787,P07602,P41440,Q9H6K4,Q14108,Q9NQ11,P98155 13 +Ovoid vertebral bodies 0.8646440348465971 2.537115895675337 0.0111769945457822 1.0 0.4782575625826351 10 P16278,P34059,P54802,P15586 4 +Rigidity 0.5516788905663277 2.524623207626201 0.0115822397185239 1.0 0.4782575625826351 64 P02792,P16278,P15289,Q15392,O75787,Q9Y287,O00592,P04062,Q9H2C2,P07602,O14936,Q9H6K4,Q9NQ11 13 +Abnormal larynx physiology 0.7387144814617326 2.506274973355763 0.0122010693085885 1.0 0.4782575625826351 17 Q13501,Q13510,Q92804,Q68CQ7 4 +Exaggerated startle response 0.876249599103316 2.503952921301174 0.0122814374999478 1.0 0.4782575625826351 9 P06865,P17900,P16278 3 +Dysmetria 0.5344910517372725 2.4974291402783355 0.0125097464020922 1.0 0.4782575625826351 68 O14773,Q8IV08,Q9NZJ4,Q9Y5Y5,Q8N0X7,Q9NUM4,Q6DKK2,Q13501,Q9BUK6,O75787,P43155,Q06787,P41440,P18887,Q6PJG6,O75503,Q99519,P98155 18 +Hyperintensity of cerebral white matter on mri 0.6885849308503963 2.494507107986711 0.0126132200233397 1.0 0.4782575625826351 22 P15289,Q9BUK6,P10253,P07602,P17900,O75503 6 +Disproportionate short limb short stature 0.6725101429900816 2.4892575037097866 0.012801021211412 1.0 0.4782575625826351 24 O75718,Q32P28,Q15392,Q8WVQ1,P10644,Q7LGA3,O00116,O94766,Q9UBM7 9 +Retinal detachment 0.6970286727120485 2.4841475756730653 0.0129861978415091 1.0 0.4782575625826351 21 O43505,P04439,Q8NCH0,Q14118,Q9H9S5,P98164 6 +Foam cells 0.9104854172070892 2.483719497742929 0.0130018178242301 1.0 0.4782575625826351 7 P16278,P61916,Q13510,O15118,Q99519 5 +Abnormal circulating lipid concentration 0.5221534544275415 2.4816687859249216 0.013076876240307 1.0 0.4782575625826351 82 Q15904,P23786,P22830,P07602,P06280,P50402,O95470,P61916,O75845,O60266,P38571,P01130,Q9Y5Y5,Q15392,O75844,Q15800,P31751,Q8N511,P34913 19 +Hepatic failure 0.5781554891796526 2.480005867164391 0.0131380220874819 1.0 0.4782575625826351 53 Q9Y5Y5,Q04446,P01889,Q13510,P23786,O15460,P22830,P04062,Q96J02,Q9Y619,P38571,O15118,Q86WC4 13 +Progressive psychomotor deterioration 0.8684419332438138 2.4711687418692425 0.0134672255523815 1.0 0.4782575625826351 9 P07686,P16278,P07602 3 +Abnormal conjunctiva morphology 0.6314859608259442 2.4676484682425666 0.0136003808170339 1.0 0.4782575625826351 31 Q13510,O00462,P02786,P06280,P10619,P04066 6 +Purpura 0.64779664850733 2.4616064607903123 0.0138316341274944 1.0 0.4782575625826351 28 P17301,Q16625,P21964,O00192,Q8NCH0,P04062,P10644,Q6YHK3,P51798,Q99519 10 +Coarse hair 0.682611334992118 2.4598498097250228 0.0138995169004985 1.0 0.4782575625826351 22 Q04721,P51688,P54802,Q9Y487,P15586 5 +Dysgraphia 0.720723760420536 2.457779197137825 0.0139799097267059 1.0 0.4782575625826351 18 Q13501,Q92673,P05067 3 +Abnormal large intestine physiology 0.6453810236979534 2.446264348300926 0.0144345123293692 1.0 0.4782575625826351 28 P15289,P21964,O94898,P07602,P06280,Q8TAA9,Q92581,Q9NQ11 8 +Delusions 0.6902178214803838 2.445397914836384 0.0144692404294859 1.0 0.4782575625826351 21 Q9BQE5,O00754,P15289,P04062,P07602 5 +Osteoarthritis 0.8043656547990804 2.4447601106967354 0.0144948517455474 1.0 0.4782575625826351 12 P01889,Q8WVQ1,P51798,P04062,Q14108 5 +Abnormality of skull ossification 0.7086852168661445 2.441681659257186 0.014619031287004 1.0 0.4782575625826351 19 Q04721,P51688,P54802,Q32P28,O75844,Q86WC4 6 +Personality changes 0.7240912710894652 2.4293869660132312 0.0151243801556473 1.0 0.4782575625826351 17 Q13501,P04062,Q9NUM4 3 +Chorioretinal dysplasia 0.8961251815341322 2.425881148027643 0.0152712705577748 1.0 0.4782575625826351 7 Q14118,O43505,P53701 3 +Abnormal neuron morphology 0.6169145975735728 2.410905377855036 0.0159129762791092 1.0 0.4782575625826351 32 P35637,Q04446,P31483,Q9NUM4,Q92804,Q13501,Q13510,Q68CQ7 8 +Periventricular white matter hyperintensities 0.8351827381499367 2.409722321427324 0.0159646660063632 1.0 0.4782575625826351 10 P17900,P07602,O75503 3 +Abnormal chorioretinal morphology 0.6216367114156625 2.402169216913145 0.0162981672050379 1.0 0.4782575625826351 31 Q9Y5Y5,O43505,P04439,Q14118,Q9Y619,Q9H9S5,P53701 7 +Muscle stiffness 0.6577518635992293 2.40027896670943 0.0163825813742817 1.0 0.4782575625826351 24 Q15392,P23786,O00592,P07602,P11166 5 +Increased cerebral lipofuscin 0.9292201481376052 2.398027363580024 0.0164836337991749 1.0 0.4782575625826351 6 O14773,P07602,O75503 3 +Kinetic tremor 0.5896118292220135 2.3979787353057125 0.0164858222731216 1.0 0.4782575625826351 41 P15289,Q9NUM4,Q9Y287,P07602,Q14108,P98155 6 +Agitation 0.5905472763309398 2.3956832270563093 0.016589420464335 1.0 0.4782575625826351 40 P42892,Q92804,Q13501,O00592,P04062,P10644,Q92673,Q68CQ7,P05067 9 +Abnormal exteroceptive sensation 0.5329047122023561 2.3879061492510556 0.0169446682635838 1.0 0.4782575625826351 65 P54802,P01889,O95831,O15460,Q8NCH0,P07686,O15269,Q06787,P07602,P06280,P11166,P05067,Q9H6K4,Q9NQ11 14 +Elevated pulmonary artery pressure 0.6189904893847215 2.3844856978581883 0.0171030127970135 1.0 0.4782575625826351 31 P01889,P51970,P51798,Q8IZA0,P04062,O75844,O96000,Q14108 8 +Petechiae 0.7408115990521504 2.381113584954758 0.0172603889154716 1.0 0.4782575625826351 15 Q16625,P10644,P04062,Q6YHK3,P51798,Q99519 6 +Respiratory failure 0.50192826365602 2.3778873334265533 0.0174121451747388 1.0 0.4782575625826351 76 Q92804,Q13501,P61916,Q13510,P23786,P10253,Q14118,Q9Y619,P07602,Q68CQ7,Q9H9S5,Q86WC4,P53701 13 +Generalized muscle weakness 0.5895334217618629 2.37213427288456 0.0176856622767096 1.0 0.4782575625826351 38 Q92804,O95831,Q13501,P10253,Q68CQ7,Q9NQ11,Q9H9S5 7 +Thickened ribs 0.948118279569896 2.367555214042363 0.0179060480199302 1.0 0.4782575625826351 5 O00754,P16278,P54802,P15586 4 +Astrocytosis 0.860923271133677 2.359529784043259 0.0182981119494467 1.0 0.4782575625826351 8 Q13501 1 +Abnormal choroid morphology 0.5900107066328895 2.3567206860827152 0.0184371088361536 1.0 0.4782575625826351 35 Q9Y5Y5,O43505,P04439,P29317,Q14118,O14936,Q9Y619,Q9H9S5,P53701 9 +Paresthesia 0.6143425100796687 2.353331256380146 0.0186060506092713 1.0 0.4782575625826351 31 P54802,P01889,O15460,P06280,P11166,P05067,Q9H6K4 7 +Hyperlipidemia 0.5958798055087234 2.3522265331713608 0.0186614060364815 1.0 0.4782575625826351 34 P01130,O95470,P31751,P23786,P22830,O75844,P06280,P50402,O60266,P38571 10 +Abnormality of corneal stroma 0.7175621617164005 2.3520473646647093 0.0186703973709903 1.0 0.4782575625826351 16 P01130,P16278,P34059,O43505,Q16625,Q13510,P10619 7 +Recurrent bacterial infections 0.6496301005760579 2.350883302019781 0.0187289066724927 1.0 0.4782575625826351 24 O00754,P53634,P15260,Q15904,P13051 5 +Abnormal morphology of the conjunctival vasculature 0.8216654782916788 2.350572457685536 0.018744557755822 1.0 0.4782575625826351 10 P10619,P06280,O00462 3 +Confusion 0.6525717556436454 2.3427916794663632 0.0191400666561474 1.0 0.4782575625826351 23 O00754,P01889,Q92673,Q9Y619,P11166,P05067 6 +Aortic valve stenosis 0.7659895753127777 2.3402223503021826 0.019272262230267 1.0 0.4782575625826351 13 Q9H9B1,P04062,P16278,O75844 4 +Heparan sulfate excretion in urine 0.94093804264452 2.339810131112136 0.0192935455977474 1.0 0.4782575625826351 5 P08236,P54802,P15586 3 +Paraparesis 0.5867067749534075 2.3330699769466543 0.0196444729054692 1.0 0.4782575625826351 35 P35637,Q9Y5Y5,Q13501,O75787,Q13510,P04062,Q9Y619,Q9H6K4,Q9NQ11 9 +Adult onset 0.5031174877554376 2.3106059545508155 0.0208546300509981 1.0 0.4782575625826351 81 Q8IV08,P02792,P43304,O43405,P31483,Q04446,O14979,Q07021,P31751,P04062,Q9UBX1,Q06787,P07602,Q9NQ11,Q9Y6M1,P41440,O15118 17 +Macular degeneration 0.7425316895301037 2.3050457595427964 0.0211640107600865 1.0 0.4782575625826351 14 Q13510,P04439,P50897 3 +Abnormal sella turcica morphology 0.8107513912287887 2.302489048853979 0.0213076082990486 1.0 0.4782575625826351 10 O00754,P16278,P08236 3 +Decreased facial expression 0.578624026418516 2.29976189113072 0.0214617135756094 1.0 0.4782575625826351 39 P02792,Q9BUK6,O75787,Q04656,O00592,P04062,Q06787,Q15043,Q13049,Q9NQ11,Q9H9S5 11 +Diffuse cerebral atrophy 0.6550463693763456 2.2979247636359244 0.0215660715880205 1.0 0.4782575625826351 22 P16278,O75787,Q06787,O14936,P07602,Q9NQ11,Q9UBX1 7 +Vertical supranuclear gaze palsy 0.723982180497021 2.2955043156591017 0.0217042393715032 1.0 0.4782575625826351 15 O15118,Q13501,P02792,P61916 4 +Macroglossia 0.5779863436749432 2.2950579122512353 0.0217298056447581 1.0 0.4782575625826351 39 Q9H9B1,O00754,P16278,P10253,P07686,Q7LGA3,P04066 7 +Abnormal cerebral artery morphology 0.681751468552019 2.292673635031796 0.0218668015268754 1.0 0.4782575625826351 19 P01130,P05067,P10253 3 +Hypoplasia of the odontoid process 0.8072137329645099 2.2868408916426906 0.0222051117289645 1.0 0.4782575625826351 10 P16278,P34059,P08236 3 +Neuronal loss in central nervous system 0.722162479725679 2.2861916503750144 0.0222430490288292 1.0 0.4782575625826351 15 P35637,P04062,P07602,Q92581,O15118 5 +Submucous cleft of soft and hard palate 0.6095622907533544 2.2836662217801975 0.0223911546558641 1.0 0.4782575625826351 30 O43505,Q15392,Q08J23,O75844,Q14118,Q9Y619,Q7LGA3 7 +Dyslexia 0.7692863648449788 2.2817744438429295 0.0225026603423821 1.0 0.4782575625826351 12 Q13501,Q9H6K4,Q9NUM4 3 +Avascular necrosis 0.6336093649719065 2.279293153847849 0.0226496447314614 1.0 0.4782575625826351 25 O00754,P01889,Q14108,O75844,P04062,Q9Y619,P51798 7 +Perseveration 0.8226461448796947 2.2760816691940553 0.0228411219987487 1.0 0.4782575625826351 9 Q13501,P61916,Q9NUM4 3 +Angiokeratoma 0.9760816984681516 2.2731238936183975 0.023018714930717 1.0 0.4782575625826351 4 P16278,P06280,O00462 3 +Anophthalmia 0.7187452616324471 2.268673663991855 0.0232881782895104 1.0 0.4782575625826351 15 Q14118,O43505,Q5SZK8,P53701 4 +Bone pain 0.6226642811363899 2.2686284608908385 0.023290929347379 1.0 0.4782575625826351 27 Q13501,P51798,P04062,P10644,P07602,P48735,Q14108 7 +Vacuolated lymphocytes 0.9747379736629947 2.267992936504432 0.0233296371991529 1.0 0.4782575625826351 4 P16278,P04066,Q99519 3 +Abnormal metatarsal morphology 0.6009210795375575 2.262691278555823 0.0236547268279772 1.0 0.4828226709693182 31 O43505,Q08J23,Q8WVQ1,Q15392,P10644,Q14118,P08236,O94766,Q9H9S5,Q9UBM7 10 +Mucosal telangiectasiae 0.7828473833885211 2.2589717948394337 0.0238851394131232 1.0 0.4839462785764008 11 Q8IZA0,P06280 2 +Echolalia 0.7490242513156478 2.2584911662229983 0.0239150546995337 1.0 0.4839462785764008 13 Q9H9B1,Q13501,Q9NUM4,P53701 4 +Truncal ataxia 0.6661259913991102 2.2540205144695347 0.0241948774387792 1.0 0.4875164407001885 20 Q92581,O75503,P98155 3 +Abnormality of pulmonary circulation 0.5733461236184403 2.2416911813393536 0.0249813382309775 1.0 0.4969916023589001 36 P01889,P51970,P51798,Q8IZA0,P04062,O75844,O96000,Q14108 8 +Diffuse white matter abnormalities 0.7446265650303598 2.237166595914988 0.0252754536969272 1.0 0.5007301016008916 13 P16278,P09471,Q3ZCQ8,O75306,O14936,Q9H9S5 6 +Inappropriate behavior 0.6435540386460014 2.229428563939972 0.0257854034630851 1.0 0.5049379095022462 22 Q13501,P17900,P07602,Q9NUM4 4 +Abnormal morphology of the abdominal musculature 0.742041161229507 2.224603123366524 0.0261078927849482 1.0 0.5049379095022462 13 Q8WVQ1,O00462,Q8NCH0 3 +Abnormal visual fixation 0.8287309582207765 2.224174221561289 0.026136724736326 1.0 0.5049379095022462 8 Q5KU26,Q13510 2 +Gingival overgrowth 0.5894112861599572 2.222543337218979 0.0262466086679216 1.0 0.5049379095022462 32 O00754,P16278,P08236,Q86WC4,Q99519 5 +Memory impairment 0.5574763387110188 2.220453523801273 0.0263879972204614 1.0 0.5049379095022462 47 Q9NUM4,P01889,Q13501,Q92673,P07602,P05067 6 +Visual fixation instability 0.9618530984606102 2.218656906185902 0.0265100749016078 1.0 0.5049379095022462 4 Q5KU26 1 +Slurred speech 0.7399006281363921 2.2141864446728947 0.0268159559552283 1.0 0.5049379095022462 13 O00592,P16278,Q9Y487,Q99519 4 +Abnormal lactate dehydrogenase level 0.6588536754700574 2.212280318855314 0.0269473021216606 1.0 0.5049379095022462 20 O43505,P23786,P10253,Q14118,P38571,P41440 6 +Young adult onset 0.7539462013877688 2.2094277939146085 0.0271448995876568 1.0 0.5049379095022462 12 P07602,O15118,O43405,Q9NQ11 4 +Weak voice 0.8250648111551008 2.2086165803373627 0.0272013211057413 1.0 0.5049379095022462 8 O00592,P04062,P02792 3 +Abnormal vascular physiology 0.527456795298407 2.2063359970723746 0.0273604827332751 1.0 0.505900690538794 60 P01889,P51970,P51798,O15460,O14678,Q8IZA0,P04062,O75844,P06280,O96000,P05067,Q14108 12 +Increased circulating antibody level 0.6554378084571918 2.1925992514390735 0.0283362651123788 1.0 0.5158513127601015 20 Q14108,P15260,P13051 3 +Abnormal muscle fiber morphology 0.4905557623077614 2.1853552414605506 0.0288628099246088 1.0 0.5176077312255913 81 P35637,Q9H2D1,P31483,O95831,Q13501,O14979,Q9BUK6,O43676,P23786,P51114,Q92673,Q14118,Q93100,P50402,Q13049,P05067,Q9H9S5 17 +Frontotemporal cerebral atrophy 0.8754533750605662 2.184785281619092 0.0289045937193723 1.0 0.5176077312255913 6 Q13501 1 +Psychomotor deterioration 0.7837435349487303 2.18224547507637 0.0290914207369632 1.0 0.5176077312255913 10 P06865,P07602,P50897 3 +Bone marrow foam cells 0.951894651975273 2.180358820809169 0.0292308740657705 1.0 0.5181337263913834 4 P61916,O15118,Q99519 3 +Deposits immunoreactive to beta amyloid protein 0.950924185531069 2.1766188636061603 0.0295090165345133 1.0 0.5211049174540461 4 P05067 1 +Abnormal femoral neck head morphology 0.5264706516635692 2.174618423255944 0.0296587225747331 1.0 0.5217943169398009 59 O00754,P16278,P34059,O75718,Q8WVQ1,O95831,P15260,O75844,Q9Y619,Q7LGA3,Q9Y487,P04066 12 +Orthostatic hypotension 0.6755493989832286 2.1686196900344386 0.0301115690455215 1.0 0.5218371969806165 17 P15289,Q04656,P04062,P07686,P07602 5 +Undetectable electroretinogram 0.948713357336478 2.168093717756938 0.0301515567412233 1.0 0.5218371969806165 4 O14773 1 +Abnormal biliary tract morphology 0.6108195195464577 2.1631748843509744 0.0305277312192637 1.0 0.5218371969806165 26 P14174,P15289,P04062,P07602,Q14108 5 +Abnormality of the ribs 0.4818467830410658 2.1612689025757543 0.0306745736287976 1.0 0.5218371969806165 77 O00754,P16278,P34059,P51688,P54802,Q32P28,O95831,O75718,Q04656,O75844,Q9Y619,P15586,Q8TAA9,P51798 14 +Lack of insight 0.946497468818 2.1595419365920754 0.0308081475038259 1.0 0.5218371969806165 4 Q13501 1 +Eeg with continuous slow activity 0.946497468818 2.1595419365920754 0.0308081475038259 1.0 0.5218371969806165 4 Q13501 1 +Collectionism 0.946497468818 2.1595419365920754 0.0308081475038259 1.0 0.5218371969806165 4 Q13501 1 +Abnormal aortic valve physiology 0.5525412047064849 2.157840623162092 0.0309402252724648 1.0 0.5218371969806165 45 Q9H9B1,P01130,O00754,P16278,P01889,O75844,P04062 7 +Central scotoma 0.7952373848345731 2.1570116504038466 0.0310047566950975 1.0 0.5218371969806165 9 O75306,Q9Y287,Q8WWV3,Q9H6K4,Q8NHS3 5 +Abnormality of the odontoid process 0.7599474089734896 2.1535907040954654 0.0312722839189845 1.0 0.5218371969806165 11 P16278,P34059,P08236 3 +Fatigable weakness of swallowing muscles 0.6958465678261513 2.150279362462618 0.0315331238233409 1.0 0.5218371969806165 15 Q13501,Q92804,Q68CQ7 3 +Hyperorality 0.8640495681180463 2.13887584775823 0.0324457245739524 1.0 0.5349006691125378 6 Q13501,Q9NUM4 2 +Decerebrate rigidity 0.8884129412710967 2.1341997088714644 0.0328264365345689 1.0 0.5349753945053628 5 P16278,P07602 2 +Abnormal rib cage morphology 0.508418079099618 2.1336409203748112 0.032872185619059 1.0 0.5349753945053628 96 O00754,P16278,P34059,P51688,P54802,Q32P28,Q8WVQ1,O95831,O75718,Q8TAA9,Q04656,P22694,O75844,Q9Y619,P08236,P15586,P51798,P04066 18 +Enlarged thorax 0.6182041474552619 2.132784208800073 0.0329424322355202 1.0 0.5349753945053628 23 Q32P28,Q7RTS9,P22694,O75844,P17612,P08236,P04066 7 +Abnormality of femur morphology 0.4913365687244141 2.1304918027491446 0.033131031854839 1.0 0.5349753945053628 85 O00754,P16278,P34059,O75718,Q32P28,Q8WVQ1,O95831,P15260,O75844,P04062,Q9Y619,P07602,P06280,Q7LGA3,Q9Y487,P51798,P04066 17 +Abnormal form of the vertebral bodies 0.521147482763706 2.127725779014986 0.0333598262459484 1.0 0.5368313336165427 105 P15586,Q8TAA9,P16278,P34059,P54802,Q32P28,P10644,Q96J02,P08236,P51798,P51688,Q8WVQ1,Q04656,P48735,P04066,Q99519,Q04721,O00754,O95831,Q9Y619 20 +Abnormal lower motor neuron morphology 0.7708315255409401 2.1241230038727226 0.0336598594030141 1.0 0.5389946523362446 10 Q13501,Q13510 2 +Abnormality of lysosomal metabolism 0.8600626054735783 2.1227691654283056 0.0337731998854438 1.0 0.5389946523362446 6 P51798,P07602,Q13510 3 +Abnormal tongue morphology 0.4853524667893698 2.117173572526449 0.0342451194176576 1.0 0.5401766754657383 82 Q9H9B1,O00754,Q9Y5Y5,P16278,P01889,Q5SZK8,O15460,P10253,O75844,P07686,Q05086,Q7LGA3,P67870,P04066,Q9H9S5,Q9UBM7,Q99519 17 +Agnosia 0.752077470359978 2.1170558716938666 0.0342551062490468 1.0 0.5401766754657383 11 P05067,Q92673,Q9NUM4 3 +Epiphyseal stippling 0.703909075060359 2.1112772727164426 0.0347484863477183 1.0 0.5407671403134902 14 Q9Y5Y5,P10644,P08236,Q9UBM7,Q99519 5 +Abnormality of the wrist 0.5511032526468389 2.1087524082191207 0.0349659585260591 1.0 0.5407671403134902 41 Q04721,P16278,P34059,Q8WVQ1,O95831,Q13510,O75844,Q9H6K4,Q9ULH0 9 +Abnormal ilium morphology 0.6062939412463014 2.1071604342254964 0.0351036752574838 1.0 0.5407671403134902 25 O00754,P16278,P34059,P01889,O95831,Q8TAA9 6 +Abnormal macular morphology 0.5613890197936688 2.105859246791254 0.0352165805754374 1.0 0.5407671403134902 34 P04439,P50897,Q13510,Q9HCM3,Q8NHS3,Q99519 6 +Recurrent aspiration pneumonia 0.8541399960267778 2.098789419239512 0.035835467966744 1.0 0.5407671403134902 6 Q13510 1 +Skeletal muscle hypertrophy 0.5329636105359613 2.095106624105695 0.0361615152314034 1.0 0.5407671403134902 52 Q9H9B1,O00754,P16278,P10253,P07686,Q14118,Q7LGA3,P04066 8 +Scotoma 0.7296580017253671 2.0935292359384388 0.0363019370527086 1.0 0.5407671403134902 12 P04439,O75306,Q9Y287,Q8WWV3,Q9H6K4,Q8NHS3 6 +Abnormality of the spleen 0.5738942298960529 2.0926355946332165 0.03638169658258 1.0 0.5407671403134902 146 P14174,P01889,P15260,Q16625,Q15904,P23458,P04062,P07602,P15586,P16278,P54802,P61916,Q13510,P10253,P07686,Q96J02,P08236,P38571,P11166,P10619,Q14108,P51798,Q86WC4,P51688,Q15392,P21964,P04066,Q99519,Q04721,O00754,O15118 31 +Emg chronic denervation signs 0.6615264421460973 2.091671599066506 0.0364679027857375 1.0 0.5407671403134902 17 P22626,P07602,Q13510,P15289 4 +Pectus carinatum 0.544078650634371 2.0915405448707394 0.0364796358588457 1.0 0.5407671403134902 45 Q04721,O00754,P16278,Q7RTS9,Q04656,Q9Y619,P55795,P08236,O94766,Q99519 10 +Hydrocephalus 0.5008750863398109 2.088308862580174 0.0367699825201457 1.0 0.5407671403134902 94 O43505,P23786,P04062,Q14118,Q8TAA9,P10644,P08236,P11166,P51798,Q86WC4,Q9UBM7,Q15392,Q08J23,P21964,O00459,P07942,O94766,P53701,Q04721,O00754,Q99519,Q9H9S5 22 +Progressive gait ataxia 0.6835489137521742 2.085968235180487 0.0369815005080997 1.0 0.5407671403134902 15 Q9NZJ4,O14773,P15289,P07602,Q9NQ11,Q05086 6 +Abnormal mitral valve physiology 0.5445821684704497 2.0851724238337357 0.0370536520814956 1.0 0.5407671403134902 44 P01130,O00754,P01889,O75844,P04062,P06280,P53701 7 +Erlenmeyer flask deformity of the femurs 0.9259252307966748 2.079810324781104 0.0375429337214372 1.0 0.5407671403134902 4 P04062,P07602 2 +Venous insufficiency 0.8108519594344602 2.073771917844795 0.0381004983954751 1.0 0.5429186174185983 7 P04062,P21964,Q04656 3 +Bilateral tonic clonic seizure with generalized onset 0.7252859382305714 2.0724899075862537 0.0382197764812306 1.0 0.5429186174185983 12 P04062,Q92581,Q13510,P11166 4 +Arthritis 0.5338987832248637 2.0723926304334666 0.0382288400812247 1.0 0.5429186174185983 50 P14174,P01889,Q8WVQ1,P10321,Q13510,O15460,P51798,O75844,P04062,P06280,Q14108 11 +Increased skull ossification 0.921927701731942 2.0642473188397488 0.0389942731114969 1.0 0.547162162832134 4 Q86WC4,P54802 2 +Infantile axial hypotonia 0.7406815543262841 2.0638624151309566 0.0390307631978339 1.0 0.547162162832134 11 O00754,P17900,P07602 3 +Abnormal csf protein level 0.6792767607221167 2.0635071573411143 0.0390644684916157 1.0 0.547162162832134 15 P02792,P15289,Q16625,P07602,Q7LG56,P55011 6 +Pulmonary infiltrates 0.7573617139632332 2.0630499901731847 0.0391078788705046 1.0 0.547162162832134 10 P15260,Q13510,P01889 3 +Schizophrenia 0.6064748094778948 2.059842982781858 0.0394135539591551 1.0 0.5476646058111838 23 Q9BQE5,P15289,Q9BUK6,P04062,P07602 5 +Cortical cataract 0.8695823189529153 2.0593642644213013 0.0394593564092786 1.0 0.5476646058111838 5 Q9HCM3 1 +Amyotrophic lateral sclerosis 0.6482346658248759 2.059020741912916 0.0394922515325137 1.0 0.5476646058111838 18 P35637,P31483,Q92804,Q13501,Q68CQ7 5 +Motor neuron atrophy 0.5985165453518849 2.0574767378485497 0.0396403902913393 1.0 0.5481068628259974 25 P35637,P31483,Q92804,Q13501,Q13510,Q68CQ7 6 +Retinal dysplasia 0.7719813974429562 2.0546148242781306 0.0399162226768836 1.0 0.5503069880745802 9 Q14118,O43505,P53701 3 +Aplasia hypoplasia involving the femoral head and neck 0.738118344277103 2.051850700437977 0.0401841742512312 1.0 0.5523859521707148 11 Q8WVQ1,P15260 2 +Vertebral compression fracture 0.6540277188135256 2.0502225277718273 0.0403427206055115 1.0 0.552953278066823 17 Q04721,P04062,Q14108,Q32P28 4 +Apraxia 0.4706627702249083 2.0475269741142 0.040606371179763 1.0 0.554953739456762 77 O14773,Q13501,Q6DKK2,P04062,Q9H270,Q7LGA3,P55011,P18887,P05067,Q92673,P11166,Q9NQ11,Q8N0X7,Q9BVA1,Q9NUM4,O75787,O00429,Q93009,P35637,Q9Y619,Q9H3S7,Q05086 22 +Abnormal urine cytology 0.5406879855715949 2.0452934282994857 0.0408259382197599 1.0 0.5557568253927373 43 P17301,Q04721,P01889,P04062,P10644,P06280,Q6YHK3,Q14108 8 +Aplasia hypoplasia of the abdominal wall musculature 0.7864440594375042 2.042945994310624 0.0410577845473183 1.0 0.5557568253927373 8 Q8WVQ1,O00462 2 +Ecchymosis 0.6752255150298435 2.04215041414791 0.0411366133747752 1.0 0.5557568253927373 15 P04062,P10644,Q8NCH0,Q6YHK3 4 +Bowing of the legs 0.4787396920083033 2.035546120250175 0.0417959528661544 1.0 0.5630511936111949 70 Q04721,O00754,P16278,P34059,O75718,Q32P28,Q8WVQ1,Q04656,Q9NX62,P22694,Q9Y619,Q7LGA3,P08236,P51798 14 +Abnormal visual electrophysiology 0.5149264385699177 2.0318651856291257 0.0421673058496974 1.0 0.5653191730708882 57 O14773,P50897,P15289,Q9HCM3,P07602,O75503 6 +Hypoplastic vertebral bodies 0.8376040419217464 2.031501932591808 0.0422041036947937 1.0 0.5653191730708882 6 P10644,P16278 2 +Progressive spastic quadriplegia 0.7491426949656754 2.0255639816465782 0.0428094856796308 1.0 0.5680010825298599 10 P17900,P07602,P15289 3 +High myopia 0.7149561002160207 2.0225659819970434 0.0431179144244289 1.0 0.5680010825298599 12 Q14118,Q9Y487,P98164 3 +Rhizomelia 0.6865025830075946 2.022405685852435 0.043134458154538 1.0 0.5680010825298599 14 O75718,Q15392,Q7RTS9,O15228,O00116,O94766,Q9UBM7 7 +Fatigable weakness of bulbar muscles 0.6489954696908102 2.022288751689884 0.0431465299958429 1.0 0.5680010825298599 17 Q13501,Q92804,Q68CQ7 3 +Psoriasiform dermatitis 0.9105079279763432 2.0196654340966345 0.0434181028327944 1.0 0.5680010825298599 4 P10321,P00533,P01889 3 +Abnormal saccadic eye movements 0.5795301179488065 2.0163844392260413 0.0437597913906262 1.0 0.5680010825298599 28 O14773,P04062,P51798,Q8IV08 4 +Diminished movement 0.5920302396096125 2.015810438280081 0.0438198016353166 1.0 0.5680010825298599 25 O95831,P51114,O00592,P04062,P13473 5 +Abnormal epiphyseal ossification 0.6251183051144983 2.015778830565895 0.0438231081539186 1.0 0.5680010825298599 20 Q9Y5Y5,Q7RTS9,P10644,O00116,P08236,Q9UG56,Q9UBM7,Q99519 8 +Xerostomia 0.6476518294932867 2.014814207698212 0.0439241198133706 1.0 0.5680010825298599 17 P35637,Q13501,Q92804,Q68CQ7 4 +Skin nodule 0.5954338793879359 2.0132580010040715 0.0440874942581859 1.0 0.5680010825298599 24 P35637,P01130,P01889,Q13510,P06280,P48735 6 +Glomerulopathy 0.7286926000824295 2.007530632791274 0.0446931922838977 1.0 0.5680010825298599 11 Q14108,P06280 2 +Partial agenesis of the corpus callosum 0.6459966784786298 2.005597449145039 0.0448992142869162 1.0 0.5690854714054033 17 Q86WC4,P98164,Q15392 3 +Zonular cataract 0.6526094436811202 2.004181740355299 0.0450505958189213 1.0 0.5692158032709036 16 P02792,Q8WWV3,Q9HCM3,P29992,P11166,Q9H6K4,P08670 7 +Abnormality of visual evoked potentials 0.5900145408047692 2.0028193354247534 0.0451966837088135 1.0 0.5692158032709036 25 P07602,O75503,P15289 3 +Abnormal atrioventricular valve physiology 0.5115080710683753 2.002121455819157 0.0452716704616307 1.0 0.5692158032709036 57 P01130,O00754,P01889,Q15904,O75844,P04062,P10644,P06280,P53701 9 +Coxa valga 0.5675264707934564 1.9981688715421544 0.0456983550852678 1.0 0.5730525112421224 30 O00754,P16278,P34059,Q8WVQ1,O75844,Q9Y619,P04066 7 +Joint stiffness 0.4928173108632471 1.9937290974463968 0.0461816677090356 1.0 0.5747820555611318 64 O00754,P16278,P51688,P54802,P01889,O75844,P15586,Q8TAA9,P50402,P08236,P48735 11 +Postural tremor 0.642746308083934 1.9874677515641008 0.0468705861431073 1.0 0.5815652991177662 17 P35637,O14773,Q9H6K4,Q14108,Q9NQ11 5 +Abnormality of epiphysis morphology 0.4665950032268448 1.9820306477298395 0.0474758105983814 1.0 0.5836503292471706 72 Q9Y5Y5,P16278,P34059,Q7Z4L5,Q8WVQ1,O95831,Q04656,P10644,Q9Y619,Q7LGA3,O00116,P08236,P51798,Q9UBM7,Q99519 15 +Retinal degeneration 0.4761387436291409 1.9779662668038187 0.047932512292075 1.0 0.5858549107373381 69 O14773,O00754,P04439,P50897,Q13510,P04062,Q9H2C2,Q7LGA3,Q9HCM3,O75503 10 +Emg myopathic abnormalities 0.5369676908874523 1.97208279703876 0.048600155454729 1.0 0.5897538453389337 36 P31483,Q13501,Q9BUK6,P51114,P13473,P50402,Q13049,Q9H9S5 8 +Genu valgum 0.5248089116705605 1.9716610427311605 0.0486483136905908 1.0 0.5897538453389337 48 Q04721,O00754,P16278,P34059,Q04656,Q9NX62,P22694,Q9Y619,Q7LGA3,P08236,P51798 11 +Dyscalculia 0.6758813049703517 1.967703513898971 0.0491021612933726 1.0 0.5913874903585404 14 P35637,Q13501,Q9NUM4,Q06787 4 +Beaking of vertebral bodies 0.6899327004578919 1.967137888435219 0.0491673162715902 1.0 0.5913874903585404 13 P16278,P08236 2 +Emg neuropathic changes 0.5575555085751495 1.962774392785078 0.0496723945225159 1.0 0.5924687447826538 31 O14773,P15289,Q13510,Q04656,P22626,P07602 6 +Abnormality of the upper respiratory tract 0.5271231752870822 1.9615597548616992 0.0498137616596319 1.0 0.5924687447826538 121 P01889,Q13501,Q7RTS9,P00533,P07602,P15586,Q8IWT6,P16278,P34059,P54802,Q13510,Q5SZK8,O15460,Q86YV9,P10644,P08236,Q10469,Q9UBM7,P51688,Q03519,P21964,P13051,Q68CQ7,P04066,Q04721,O00754,P35637,Q92804,O00192,Q06787,Q15833 31 +Hypercholesterolemia 0.6887063702158587 1.9609808284936932 0.0498812593517945 1.0 0.5924687447826538 13 P01130,Q15904,P38571 3 +Abnormal femoral head morphology 0.5832909521696589 1.959339039748168 0.0500730946357641 1.0 0.5924687447826538 25 P16278,Q8WVQ1,O95831,P15260,Q7LGA3 5 +Bilateral talipes equinovarus 0.7834537200550397 1.9574903754619983 0.0502898422519153 1.0 0.5924687447826538 7 Q15392 1 +Increased circulating igm level 0.7341117253036973 1.956578475722129 0.0503970476844102 1.0 0.5924687447826538 10 P15260 1 +Premature loss of primary teeth 0.8932579269439047 1.9519843735311573 0.0509400598970413 1.0 0.5924687447826538 4 P53634 1 +Severe short stature 0.5454721886571963 1.9497863795835673 0.0512015856387506 1.0 0.5924687447826538 33 P16278,Q15392,Q8WVQ1,P10619,P53701 5 +Elevated serum acid phosphatase 0.8924465418000982 1.9487910469539016 0.0513203833928128 1.0 0.5924687447826538 4 P07602 1 +Ventricular preexcitation 0.8412542278081494 1.9456981971326337 0.0516910033517528 1.0 0.5924687447826538 5 P13473 1 +Abnormal iliac wing morphology 0.6711690792664224 1.9433195180219904 0.0519775646794387 1.0 0.5924687447826538 14 O95831,P16278,P34059,Q8TAA9 4 +Abnormal heart sound 0.8158845323894929 1.9423789356276355 0.052091243424263 1.0 0.5924687447826538 6 P01130,P10253 2 +Restrictive behavior 0.7798524589756411 1.9420939172516791 0.05212573175902 1.0 0.5924687447826538 7 Q13501 1 +Incoordination 0.4662800640889399 1.9383397376109377 0.0525817873313292 1.0 0.5924687447826538 81 O14773,O00754,P31483,P15289,Q13501,O75787,Q13510,P04062,Q9Y619,Q05086,P07602,Q9H9S5,O75503 13 +Cerebral calcification 0.5306300010284783 1.938100527454918 0.0526109591314194 1.0 0.5924687447826538 39 P53634,O75845,Q16625,P22413,O00584,P23786,O00429,Q04656,Q14118,P11166,P05067,P29992 12 +Abnormal circulating igm level 0.6040381866967137 1.938100011109767 0.0526110221146027 1.0 0.5924687447826538 21 P15260,P13051 2 +Alkalosis 0.8888793656791526 1.9347416010387888 0.0530220126221787 1.0 0.5924687447826538 4 P01889 1 +Fatigable weakness of respiratory muscles 0.6326191311582648 1.9307268859701 0.0535168362113762 1.0 0.5924687447826538 17 Q13501,Q92804,Q68CQ7 3 +Hypokinesia 0.638724731551583 1.927849210202537 0.0538738847098168 1.0 0.5924687447826538 16 Q2TAA5,O95831,P04062,P13473,Q9NQ11 5 +Polar cataract 0.835360939542096 1.9218912465379936 0.0546194434953992 1.0 0.5924687447826538 5 Q7LGA3,Q9Y287 2 +Abnormal brain positron emission tomography 0.7582149048528486 1.9198070613510432 0.0548822746053168 1.0 0.5924687447826538 8 Q13501 1 +Abdominal distention 0.5731031376892001 1.917850652002126 0.0551299510143159 1.0 0.5924687447826538 26 P15289,Q7RTS9,Q5SZK8,Q01844,P04062,P07602,Q7LG56,P38571 8 +Metaphyseal widening 0.5461044035919411 1.916901723075701 0.0552504181434176 1.0 0.5924687447826538 32 P16278,P34059,Q8WVQ1,O95831,Q04656,Q86WC4 6 +Osteolysis 0.5354137899668168 1.9153560759308763 0.0554471087362162 1.0 0.5924687447826538 34 Q04721,O00754,P53634,Q13501,Q04656,O75844,P04062,P48735,Q14108 9 +Barrel shaped chest 0.7731267166916871 1.913270301193953 0.0557134576832638 1.0 0.5924687447826538 7 P04066,Q32P28 2 +Abnormal femoral neck morphology 0.5158317894514508 1.9104206185394024 0.0560790781913498 1.0 0.5924687447826538 49 O00754,P16278,P34059,O75718,Q8WVQ1,O95831,O75844,Q9Y619,Q9Y487,P04066 10 +Endocarditis 0.8073108715091846 1.9069697406946549 0.0565245060230759 1.0 0.5924687447826538 6 P04062,P01889 2 +Acne 0.6281937207343826 1.905811283253137 0.056674694498763 1.0 0.5924687447826538 17 P01889,P22413,Q92542,P21964,O00192,P17612 6 +Biliary tract neoplasm 0.8307336472744695 1.903160666020586 0.0570195839078984 1.0 0.5924687447826538 5 P07602 1 +Neoplasm of the gallbladder 0.8307336472744695 1.903160666020586 0.0570195839078984 1.0 0.5924687447826538 5 P07602 1 +Epistaxis 0.6489552484280164 1.9023131667685491 0.0571302253582453 1.0 0.5924687447826538 15 P04062,P10644,O15460,P01889 4 +Punctate cataract 0.8293694990120211 1.8976324965580031 0.0577445105090528 1.0 0.5924687447826538 5 P02792,Q8WWV3,Q9H6K4 3 +Sensorimotor neuropathy 0.5275340786319912 1.8975731843907333 0.057752329651165 1.0 0.5924687447826538 35 Q9NZJ4,O95831,O00429,Q5KU26,P07602,Q7LG56,P41440,P18887,Q9Y2R0 9 +Lymphedema 0.6473577777804669 1.8937344556568432 0.0582602654548776 1.0 0.5924687447826538 15 P06280 1 +Resting tremor 0.5729159807337268 1.8918012467215997 0.0585174671395072 1.0 0.5924687447826538 25 P02792,O75787,O00592,P04062,P07602,Q9H6K4,Q9NQ11 7 +Diplopia 0.5610380303096973 1.8915139869945543 0.0585557656561435 1.0 0.5924687447826538 28 O14773,P01889,O15460,O00592,P04062 5 +Restlessness 0.5160594671194508 1.888694669111676 0.0589327533569441 1.0 0.593615199995018 47 P42892,Q92804,Q9NUM4,Q13501,O00592,P04062,P10644,Q92673,Q68CQ7,P05067 10 +Chronic pulmonary obstruction 0.7509528843190777 1.887853758450857 0.0590455858542615 1.0 0.593615199995018 8 P21964,P06280 2 +Ulnar deviation of the wrist 0.8267977026221935 1.8872026095755696 0.0591330794564679 1.0 0.593615199995018 5 P16278,P34059 2 +Vertebral hypoplasia 0.7029467079566697 1.885281977801713 0.0593917780118518 1.0 0.5942802011911992 11 Q04721,P10644,P16278 3 +Joint subluxation 0.7664450101312937 1.8845468766548945 0.0594910402889174 1.0 0.5942802011911992 7 P16278 1 +Facial hypotonia 0.7021575760343772 1.8815075752789192 0.0599029057798778 1.0 0.5956714446870075 11 P10253 1 +Abnormal pleura morphology 0.5671492381961023 1.87845731052056 0.0603186317464052 1.0 0.5956714446870075 26 P14174,P01889,Q8NCH0,O15460,P08236 5 +Aspiration 0.701246918745388 1.8771499071315905 0.0604975508796052 1.0 0.5956714446870075 11 P17900 1 +Erythema 0.5668406753208558 1.8764107642801904 0.0605988976185745 1.0 0.5956714446870075 26 P07858,P01889,P22830,P00533,Q07954,P53701 6 +Progressive spasticity 0.609053153807644 1.8761040373110809 0.0606409954294302 1.0 0.5956714446870075 19 P17900,P07602,P15289 3 +Prominent sternum 0.8735255917285528 1.8740820881222944 0.0609191117231895 1.0 0.5962968834058284 4 P16278,P34059 2 +Hypertensive crisis 0.7989734959538826 1.8724146179216223 0.061149264226934 1.0 0.5962968834058284 6 P21964,P01889 2 +Abnormal intraocular pressure 0.7628266531627921 1.8689556590392455 0.0616289836373935 1.0 0.5962968834058284 7 P04439,Q8NCH0,Q15043,P29992,Q92560 5 +Increased vertebral height 0.8718228155544421 1.867336341467029 0.0618546334437311 1.0 0.5962968834058284 4 Q04721,O00754 2 +Rapidly progressive 0.6829610128232448 1.8660264276522447 0.0620376681438574 1.0 0.5962968834058284 12 Q14108,Q8NHS3 2 +Flaring of rib cage 0.8703832850483368 1.8616306568551704 0.0626551689640986 1.0 0.5962968834058284 4 P16278 1 +Varicose veins 0.7963067597035409 1.8613369765614831 0.0626966045218668 1.0 0.5962968834058284 6 P04062,P21964 2 +Disproportionate short trunk short stature 0.7445920916364198 1.85977450359335 0.0629174360617463 1.0 0.5962968834058284 8 P16278 1 +Infantile muscular hypotonia 0.4522758010991584 1.8573984064658733 0.0632544930354599 1.0 0.5962968834058284 77 O00754,P16278,Q13510,P10253,Q96J02,Q14118,O14936,P07602,Q9Y487,P16870,P17900,Q15043,Q9H9S5,Q99519 14 +Cerebral palsy 0.654378538487807 1.8558624724516208 0.0634731632110041 1.0 0.5962968834058284 14 P17301,Q9BVA1,Q6YHK3,P48735,P98155 5 +Bulbar signs 0.6808436207806832 1.8555656651367856 0.0635154914503621 1.0 0.5962968834058284 12 P04062,Q15043,P07602,P15289 4 +Abnormal pericardium morphology 0.667774409792076 1.8551961496884668 0.0635682213185446 1.0 0.5962968834058284 13 P04062,Q14108,P14174,P01889 4 +Generalized clonic seizure 0.7435115577432367 1.854996133953383 0.0635967786541673 1.0 0.5962968834058284 8 O14936,P07602 2 +Impaired proprioception 0.5154105678845285 1.8540583519878 0.063730812260923 1.0 0.5962968834058284 44 O14773,Q8IV08,P54802,Q9Y619,P41440,Q9H6K4,Q9NQ11 7 +Hypomimic face 0.6190316793021056 1.8539948264503912 0.0637399001562115 1.0 0.5962968834058284 17 P02792,O00592,P04062,Q9NQ11,Q15043 5 +Meningitis 0.742480799844789 1.8504356116004728 0.0642507902943911 1.0 0.5997832477511467 8 P02786,Q8TAA9,P01889 3 +Platybasia 0.7422986335639263 1.849629397949859 0.0643669826854889 1.0 0.5997832477511467 8 Q04721,P21964,P14543 3 +Thoracic kyphosis 0.5970266152745091 1.8485070367192848 0.0645290273695597 1.0 0.6001072269180955 20 P04062,Q9UPP1,P08236,O00754 4 +Osteopetrosis 0.8661006604213702 1.8446410306470604 0.0650897742148917 1.0 0.6021616016637141 4 Q86WC4,Q15392 2 +Abnormal leukocyte physiology 0.4477842446480288 1.8430309245196257 0.0653244954846195 1.0 0.6021616016637141 75 Q8IWT6,O00754,Q9Y2Q5,P14174,Q15477,P15260,Q15904,P21964,O75787,P13051,O00192,P04062,Q96J02,P02786,Q15833,Q14108 16 +Multifactorial inheritance 0.6517947248448428 1.8423250886368028 0.0654276120786598 1.0 0.6021616016637141 14 P42892,P10321 2 +Nephrotic syndrome 0.5351363558850718 1.837697267701162 0.0661070267189603 1.0 0.6033407365987882 32 O95470,Q96J84,Q07021,Q8NCH0,P23458,P51809,P06280,Q13049,Q14108 9 +Abnormal midbrain morphology 0.7084152400386113 1.837362873889879 0.0661563437585521 1.0 0.6033407365987882 10 P04062 1 +Chronic fatigue 0.7218856641726862 1.8298051869995875 0.0672790749121972 1.0 0.6112154878824851 9 P07602 1 +Angina pectoris 0.8122082364842841 1.8278459639205769 0.0675726727155676 1.0 0.6127022151036567 5 P01130,P06280 2 +Restrictive ventilatory defect 0.6618545335351164 1.8250429575301068 0.0679945470816592 1.0 0.6149800755747629 13 P16278,P34059,P01889 3 +Recurrent infection of the gastrointestinal tract 0.719870570427432 1.8206430869340713 0.0686611286988783 1.0 0.6149800755747629 9 O00754,P15260 2 +Acetabular dysplasia 0.704736295968097 1.8201642093599135 0.0687340017518398 1.0 0.6149800755747629 10 P16278 1 +Horizontal nystagmus 0.561621543325023 1.8176640605379957 0.0691154939771603 1.0 0.6149800755747629 25 O14773,Q9NZJ4,O95831,P04062,P07602,Q9NQ11,Q9NWX6 7 +Pedal edema 0.7350304710382998 1.817406393421359 0.0691549095114265 1.0 0.6149800755747629 8 P04062,Q14108 2 +Primitive reflex 0.7348027801426898 1.816395171030163 0.0693097754275871 1.0 0.6149800755747629 8 P17900,Q9UBX1 2 +Gingival bleeding 0.6884896374693986 1.815878211911679 0.0693890562472479 1.0 0.6149800755747629 11 P04062,Q14108 2 +Subcutaneous hemorrhage 0.5010989169912843 1.8132604999394604 0.069791652518053 1.0 0.6157062166815559 51 P17301,P22413,Q16625,P21964,Q86YV9,P51798,Q9NWM8,Q8NCH0,P04062,P10644,Q04656,O00192,P17612,Q6YHK3,Q15833,Q14108,Q99519 17 +Saccadic smooth pursuit 0.7846778610502619 1.8128904124702456 0.0698487252661479 1.0 0.6157062166815559 6 O14773 1 +Progressive cerebellar ataxia 0.5112827876327624 1.8127995626974096 0.0698627414474299 1.0 0.6157062166815559 43 P35637,O14773,Q13501,Q9BUK6,Q9Y619,Q9Y487,P41440,Q9NQ11 8 +Vegetative state 0.8080260901947551 1.8107727788672696 0.0701760316636339 1.0 0.6173134128620039 5 P07602 1 +Abnormal vertebral morphology 0.5265907404128674 1.807619385614863 0.0706657589766852 1.0 0.6204637869181955 132 P04062,P15586,Q8TAA9,P16278,P34059,O75718,P54802,Q32P28,Q5SZK8,P10644,Q96J02,P08236,P10619,P51798,Q14108,P51688,Q8WVQ1,Q8NCH0,Q04656,P48735,P04066,Q99519,Q04721,O00754,O95831,Q9Y619,Q9H9S5 27 +Muscle spasm 0.4525316582998195 1.8057216629598656 0.0709618271192065 1.0 0.6209935374863694 71 Q92804,Q13501,P23786,O00592,P04062,P13473,P06280,Q68CQ7,Q9H6K4,Q9H9S5 10 +Hypocalcemia 0.6039318938011533 1.8053395682925248 0.0710215614348874 1.0 0.6209935374863694 18 Q4J6C6,P21964,O00192,P10644,P51798,Q86WC4 6 +Cirrhosis 0.5081828347206381 1.8045008312489657 0.0711528289696328 1.0 0.6209935374863694 45 Q15904,O75787,P22830,P04062,Q96J02,P38571,P11717,Q14108 8 +Abnormal metacarpal morphology 0.5107971563894141 1.8016143382468852 0.0716061038094835 1.0 0.6209935374863694 42 P16278,P34059,Q32P28,Q9NX62,P10644,P08236 6 +Bilateral sensorineural hearing impairment 0.5478530046743646 1.801348075026479 0.0716480348658716 1.0 0.6209935374863694 28 P17301,P38159,P15289,Q13501,P07602,Q6YHK3 6 +Anorexia 0.5136226006737977 1.794416284689387 0.0727467496032843 1.0 0.6275672657896552 36 P01889,P15260,Q13423,P04062,P06280,Q14108 6 +Paralysis 0.4918458880676834 1.7938385978919411 0.0728389342771127 1.0 0.6275672657896552 55 Q92804,Q13501,P10253,P04062,P50402,P11166,Q68CQ7,P17900,P51798 9 +Exercise induced muscle cramps 0.7799699005368848 1.7932128947979524 0.0729388890037605 1.0 0.6275672657896552 6 P13473 1 +Abnormality of the calf 0.4490363699603159 1.791040844159683 0.0732867408705035 1.0 0.6291217161100772 79 Q04721,O00754,P16278,P34059,O75718,Q32P28,Q8WVQ1,O95831,Q04656,Q9NX62,P22694,Q9Y619,Q7LGA3,P08236,P51798 15 +Cerebral amyloid angiopathy 0.993553585817889 1.7904200192324693 0.0733864143924798 1.0 0.6291217161100772 2 Q9Y287 1 +Calcification of the aorta 0.7443561736852522 1.788973193623299 0.0736191327760749 1.0 0.6299713448987172 7 P01130 1 +Flat face 0.532314478233393 1.7831390152107187 0.0745636767848978 1.0 0.6346474229478657 31 Q9H9B1,O00754,Q9Y5Y5,Q9NX62,Q9Y487,P08236 6 +Progressive peripheral neuropathy 0.850635125858802 1.783103912536864 0.074569389674044 1.0 0.6346474229478657 4 P07602 1 +Pustule 0.8503058871666669 1.7817908323018925 0.0747833478307735 1.0 0.6353215946344096 4 P53634,P07858 2 +Abnormal astrocyte morphology 0.5703136240476813 1.7788750018576092 0.0752602573152509 1.0 0.6370774025878069 22 P48735,Q13501,Q9NUM4 3 +Dysphasia 0.5698625143709213 1.776024108000808 0.0757289436629584 1.0 0.6394682537069469 22 Q9H9B1,Q9NUM4,Q13501,Q9H9P8,P21964,O00192,P53701 7 +Abnormal ldl cholesterol concentration 0.6388095630352866 1.7739750894250994 0.076067270854581 1.0 0.6394682537069469 14 P01130,Q8N511,Q15800,P38571,P50402 5 +Deformed sella turcica 0.7406025737239768 1.7726395537953292 0.076288453119437 1.0 0.6398804674913703 7 Q04721,P08236 2 +Episodic pain 0.6384231550797678 1.7719330978864272 0.0764056634565517 1.0 0.6398804674913703 14 Q13423,P07686 2 +Hypersplenism 0.6940927548160482 1.7702252443170896 0.0766896255712505 1.0 0.6411198307951179 10 P04062,Q14108,P07602,P38571 4 +Clonic seizure 0.7078728480119073 1.7659063568118292 0.0774115605576524 1.0 0.642597725403752 9 O14936,P07602 2 +Increased circulating lactate dehydrogenase concentration 0.6217367816173719 1.7549739544073857 0.0792637629385861 1.0 0.6556642846586558 15 P38571,P23786,P10253 3 +Slow saccadic eye movements 0.6599198241882668 1.751527652576787 0.0798550623371185 1.0 0.656645457460509 12 P04062,Q8IV08 2 +Underdeveloped supraorbital ridges 0.6593041153149354 1.7484480436545935 0.0803864748726514 1.0 0.6591690939557423 12 Q99519,Q08J23 2 +Thoracolumbar kyphosis 0.7022599526202888 1.7401905219200735 0.0818255693504708 1.0 0.663146351542453 9 O00754,P08236 2 +Metatarsus adductus 0.6187182653092108 1.7384820160665946 0.0821259162273602 1.0 0.663146351542453 15 P08236,O94766,Q15392,Q08J23 4 +Abnormal tongue physiology 0.5857426211029927 1.7380232594284613 0.0822067154559296 1.0 0.663146351542453 19 O95831,Q13510,P51114,P10253,Q9NQ11 5 +Abnormality of the elbow 0.4488173374831204 1.7364367801524057 0.0824866336331942 1.0 0.663146351542453 70 Q04721,P34059,Q8WVQ1,Q13510,P23786,Q04656,P10644,Q96J02,Q9Y619,Q7LGA3,P50402,Q9H6K4 12 +Multifocal cerebral white matter abnormalities 0.7660030535532945 1.7346251899051233 0.0828072147537781 1.0 0.663146351542453 6 P10253 1 +Calvarial hyperostosis 0.7892090589366562 1.733644397709271 0.0829811977539867 1.0 0.663146351542453 5 P10644,Q15043 2 +Hypotension 0.5205077545015429 1.7309191863759783 0.0834661790962181 1.0 0.6645057870663907 32 P15289,Q04656,Q13423,P04062,P07686,Q06787,P07602 7 +Abnormal cardiac ventricular function 0.5542437339728389 1.7270748008390182 0.0841542305560048 1.0 0.6662232546512287 23 O75844,P01130,P10253 3 +Emotional lability 0.4642461480813747 1.724175650693242 0.0846761384113334 1.0 0.6662232546512287 64 P35637,P02792,Q8N0X7,Q92804,P15289,P17252,O43681,Q13501,O75306,Q9UBX1,P10644,P07602,Q7KZN9,P17612,Q68CQ7,P29992,Q92560 17 +Abnormality of earlobe 0.5284338008848932 1.7236457454990328 0.0847718149137588 1.0 0.6662232546512287 30 Q9H9B1,Q04721,Q15392,P10586,Q7LGA3,P53701 6 +Decreased absent ankle reflexes 0.5832821982551267 1.7233220985649649 0.0848302936645062 1.0 0.6662232546512287 19 Q9NZJ4,Q13501,Q9H6K4,O75787 4 +Broad based gait 0.5324564182861644 1.7225615454890286 0.0849678440560417 1.0 0.6662232546512287 29 O14773,Q9NUM4,P98155 3 +Decreased circulating iga level 0.6529437643550253 1.7165753086680466 0.0860567971306702 1.0 0.6662232546512287 12 Q15904,P13051 2 +Meningocele 0.6279329062897793 1.716320611091877 0.0861033779436939 1.0 0.6662232546512287 14 O75845,P21964,Q5SZK8,Q8TAA9,Q9H9S5 5 +Macrogyria 0.7266793905186743 1.7118247670612954 0.0869289663799075 1.0 0.6662232546512287 7 Q14118,O43505,Q9H9S5,Q15392 4 +Myoclonus 0.4897859342962313 1.7109948468893457 0.0870820641070224 1.0 0.6662232546512287 112 O14773,P27544,Q9NWW5,P04062,P07602,P05067,Q9UBX1,O75503,P50897,O75845,Q13510,Q92673,P67870,P11166,Q14108,Q9NQ11,P02792,Q9H2C2,O14936,Q99519,O00592,Q05086 22 +Abnormal circulating igg level 0.5741590871381758 1.7098993028412552 0.0872844953953633 1.0 0.6662232546512287 20 P15260,P13051 2 +Abnormality of ocular smooth pursuit 0.5419192727646718 1.7095042111379124 0.087357592335644 1.0 0.6662232546512287 26 O14773,P02792,O00754,Q06787,P41440 5 +Abnormality of dental color 0.8322017505938343 1.7094019414586454 0.0873765215597497 1.0 0.6662232546512287 4 P16278,P34059 2 +Specific learning disability 0.4470578225474756 1.705916490787941 0.0880236289419669 1.0 0.6662232546512287 83 Q9H9B1,O00754,P35637,O43505,Q96EK5,Q9NUM4,Q13501,P21964,Q04656,P10644,Q14118,Q9Y619,Q06787,P22626,P11166,Q9H6K4,Q9H9S5,P53701 18 +Abnormally large globe 0.6506798385824704 1.7052041535629054 0.0881563556399165 1.0 0.6662232546512287 12 Q14118,O14936,Q9H9S5,O94766 4 +Mild short stature 0.8304934397038735 1.7025531654278836 0.0886517210498567 1.0 0.6662232546512287 4 P10644 1 +Left ventricular hypertrophy 0.5254251880225258 1.702155453582907 0.0887262308973513 1.0 0.6662232546512287 30 Q07021,O75787,P10253,P00533,P06280,Q9H9S5 6 +Increased ldl cholesterol concentration 0.6644930166740065 1.6995004901098498 0.0892249223056249 1.0 0.6662232546512287 11 P01130,Q8N511,P38571,P50402 4 +Hyperlipoproteinemia 0.6644930166740065 1.6995004901098498 0.0892249223056249 1.0 0.6662232546512287 11 P01130,Q8N511,P38571,P50402 4 +Mandibular prognathia 0.4890821540281735 1.6982482400009835 0.0894609192873512 1.0 0.6662232546512287 50 Q9H9B1,O00754,P16278,P34059,Q7RTS9,Q9BUK6,P22694,P10644,Q06787,P67870,Q92581,Q05086 12 +Fractures of the long bones 0.8292241348240911 1.697462460750102 0.0896092624419493 1.0 0.6662232546512287 4 Q13501 1 +Tissue ischemia 0.5494995787018727 1.6962062837690957 0.0898468208621501 1.0 0.6662232546512287 23 O75844,P05067,P06280,P01889 4 +Abnormality of lipoprotein cholesterol concentration 0.6106215253561003 1.6940968967216117 0.0902468719358438 1.0 0.6662232546512287 15 P01130,Q8N511,Q15800,P38571,P50402 5 +Finger agnosia 0.979087519145904 1.692165098561187 0.0906144990646331 1.0 0.6662232546512287 3 P05067 1 +Positive romberg sign 0.6775601646178371 1.692128539181681 0.0906214680245698 1.0 0.6662232546512287 10 Q8IV08,Q9H6K4 2 +Proportionate short stature 0.4953525987156471 1.6915431865002506 0.0907331068536614 1.0 0.6662232546512287 44 P16278,Q15392,Q8WVQ1,P10644,P10619,P53701 6 +Disinhibition 0.4556679754181066 1.6914698734380784 0.0907470969583514 1.0 0.6662232546512287 66 P35637,P02792,Q9NUM4,Q08J23,Q13501,O00592,P04062,Q92673,Q9H2C2,Q8TAA9,P05067 11 +Akinesia 0.6473225064247632 1.6883158765127426 0.0913506091517257 1.0 0.6662232546512287 12 O00592,P04062,P51114 3 +Acute coronary syndrome 0.5556184550841006 1.6855318783999709 0.0918859997136352 1.0 0.6662232546512287 22 P01130,P06280,P01889 3 +Abnormality of humoral immunity 0.4522660078781726 1.684524334197651 0.092080380690533 1.0 0.6662232546512287 67 O00754,P14174,P15260,Q15904,P13051,P04062,Q96J02,P02786,Q14108 9 +Respiratory arrest 0.6900988234284939 1.6842410708966375 0.0921350888555068 1.0 0.6662232546512287 9 P13473 1 +Abnormal aldolase level 0.8258171552638491 1.6837902616886986 0.092222209901811 1.0 0.6662232546512287 4 Q14118,O43505 2 +Hydrops fetalis 0.482337778964797 1.679607274931591 0.0930337513097214 1.0 0.6670461160279467 53 P16278,Q13510,P04062,P08236,P10619,Q99519 6 +Premature loss of teeth 0.6077069301141371 1.6780671654613548 0.0933339877800436 1.0 0.6670461160279467 15 O75844,P51798,P53634 3 +Abnormality of the vestibulocochlear nerve 0.8240385372646333 1.676648058662228 0.0936113231395787 1.0 0.6670461160279467 4 O43405 1 +Bloody diarrhea 0.6740090161887197 1.675271610989311 0.0938809528070261 1.0 0.6670461160279467 10 P17301,P00533,Q02241,Q6YHK3 4 +Short thorax 0.6878398168099702 1.6738135920605886 0.0941672402181297 1.0 0.6670461160279467 9 Q99519,Q5SZK8,Q7Z4L5,P11166 4 +Abnormality of the alveolar ridges 0.6864879894356184 1.6675685093582784 0.0954014138858008 1.0 0.6683488231147191 9 P53634 1 +Vascular calcification 0.7012646952156976 1.6663024331572447 0.0956531923586156 1.0 0.6683488231147191 8 P01130 1 +Abnormal acetabulum morphology 0.5523718913844892 1.6647788244267012 0.0959568901168963 1.0 0.6683488231147191 22 Q8WVQ1,P16278,P08236 3 +Middle age onset 0.6573826514094275 1.6647411896368631 0.0959644015373626 1.0 0.6683488231147191 11 P02792,P07602 2 +Aplasia hypoplasia involving the sinuses 0.7476464437012948 1.6571596551599534 0.097487200894631 1.0 0.6756421858285899 6 P10644,P04066 2 +Dermal atrophy 0.5144841748918652 1.653979684459184 0.0981316405431482 1.0 0.6775749747719968 31 Q15392,P53634,Q8NCH0,O75844,P10644,Q07954 6 +Orthostatic hypotension due to autonomic dysfunction 0.6691870668647236 1.6523367629522776 0.0984659189263938 1.0 0.6775749747719968 10 P04062,P07602 2 +Recurrent skin infections 0.602935318543208 1.651764891331196 0.098582488376159 1.0 0.6775749747719968 15 P02786,Q8NCH0,P53634 3 +Abnormality of hepatobiliary system physiology 0.4476967224205275 1.6491632955209974 0.0991141852710826 1.0 0.6802378217658728 87 Q04446,P01889,Q16625,O75306,P23786,P22830,P04062,O75845,Q13510,O15460,Q96J02,P38571,Q86WC4,Q9Y5Y5,O75787,Q8N511,Q9Y619,Q15833,O15118 19 +Abnormal erythrocyte sedimentation rate 0.6682324173320395 1.647789947770397 0.0993957825180664 1.0 0.6807150059777572 10 P15260,P14174,O15460,P01889 4 +Sea blue histiocytosis 0.9672219236969366 1.6474165401679166 0.0994724579254877 1.0 0.6807150059777572 3 P61916,P16278 2 +Abnormal thoracic spine morphology 0.5089064012201575 1.6453145432872665 0.0999049622309773 1.0 0.6812989253655628 32 O00754,O95831,O75845,Q7RTS9,O75844,P04062,Q96J02,Q9UPP1,O00459,P08236 10 +Myelopathy 0.7677833452651335 1.6452389768352724 0.099920538573639 1.0 0.6812989253655628 5 P16278 1 +Occipital encephalocele 0.7442902863774997 1.6429419367677256 0.1003949471627154 1.0 0.6820780632164315 6 O43505,Q9H9S5 2 +Abnormal vitreous humor morphology 0.6666314886028041 1.6401604767654865 0.1009718046580889 1.0 0.6830445609223665 10 Q92560,P29992,P04439,P53701 4 +Cataplexy 0.8144893739787427 1.6382502530323375 0.1013695004780572 1.0 0.6847524280143839 4 P61916 1 +Hand muscle weakness 0.6128625819062291 1.635840251517871 0.1018730253604536 1.0 0.6865951002203614 14 Q13501 1 +Bulbar palsy 0.6238736926227243 1.6291662254223338 0.1032778347336724 1.0 0.6865951002203614 13 Q13501,P31483,P15289 3 +Bradykinesia 0.5067052884742712 1.6289812326392972 0.1033169919549166 1.0 0.6865951002203614 32 P02792,O75787,O00592,P04062,Q06787,Q9NQ11,Q15043 7 +Posterior polar cataract 0.8111539960840505 1.6248184806517505 0.1042012420491096 1.0 0.6865951002203614 4 P29317,Q9Y287 2 +Bacterial endocarditis 0.9527262959978507 1.6237158905944318 0.1044364580098049 1.0 0.6865951002203614 2 P04062 1 +Atrophic scars 0.6909090472974253 1.6195147619245889 0.1053365529183334 1.0 0.6865951002203614 8 Q07954,Q8NCH0,P53634 3 +Cardiovascular calcification 0.6480904169950779 1.619130931822887 0.1054190947674962 1.0 0.6865951002203614 11 P01130,P04062 2 +Abnormality of the distal phalanges of the toes 0.705352867793463 1.617998934209603 0.1056628273529411 1.0 0.6865951002203614 7 Q8WVQ1,Q7LGA3 2 +Mitral stenosis 0.8093863489894976 1.6176960255524542 0.1057281229572031 1.0 0.6865951002203614 4 O75844,P04062 2 +Thickened nuchal skin fold 0.571572561646811 1.6152675831243382 0.1062527605299465 1.0 0.6865951002203614 18 Q13501,Q9NUM4 2 +Global brain atrophy 0.5518445175387451 1.6151710218733764 0.106273664090009 1.0 0.6865951002203614 21 P35637,Q13501,Q9H9P8,P07602 4 +Cognitive impairment 0.57738822603828 1.6135408911868765 0.1066270468284191 1.0 0.6865951002203614 190 Q9BQE5,Q04446,P01889,Q13501,Q6DKK2,P27544,Q9Y287,Q9NWW5,P13473,P04062,P07602,P06280,Q9Y487,P05067,P17900,Q9H6K4,Q9UBX1,O75503,P16278,P50897,P54802,P15289,P06865,P61916,Q13510,P07686,Q92673,P10644,P11166,Q14108,Q9NQ11,P02792,Q9Y5Y5,P31483,Q9NUM4,P21964,Q9H2C2,Q9Y2R0,P35637,O95831,O00592,Q06787,Q9Y619,Q9H9S5,O15118,Q8NHS3 46 +Hip osteoarthritis 0.95004029008864 1.6127277104972622 0.1068036774892564 1.0 0.6865951002203614 2 P01889 1 +Opsoclonus 0.9500402900886392 1.6127277104972602 0.1068036774892569 1.0 0.6865951002203614 2 P04062 1 +Saccadic oscillation 0.9500402900886392 1.6127277104972602 0.1068036774892569 1.0 0.6865951002203614 2 P04062 1 +Neoplasm of the male external genitalia 0.6465155879246299 1.611380563671356 0.1070968008862267 1.0 0.6865951002203614 11 Q13423,P10644,Q14145,P51809 4 +Thin ribs 0.5950388677020376 1.6080776609758052 0.1078181710643013 1.0 0.6865951002203614 15 O95831,O75844,Q32P28 3 +Esophageal varix 0.7358457226021559 1.6070965770354348 0.1080331840791188 1.0 0.6865951002203614 6 P04062,P38571 2 +Thoracic hypoplasia 0.4890595477298904 1.6057004418692116 0.1083397441704518 1.0 0.6865951002203614 37 O75718,Q8WVQ1,Q04656,P22694,P04062,Q92581,P51798 7 +Short stepped shuffling gait 0.9561183484776036 1.6054798069603378 0.108388253598227 1.0 0.6865951002203614 3 O00592 1 +Pericarditis 0.7346165002915088 1.6018704269819697 0.109184265267459 1.0 0.6865951002203614 6 P14174,P01889 2 +Polyneuropathy 0.5496568434042419 1.6013799464449434 0.1092927915785417 1.0 0.6865951002203614 21 O95831,P07602,P04066 3 +Aphasia 0.4802618336230218 1.601138066149195 0.1093463426822058 1.0 0.6865951002203614 48 Q9H9B1,P31483,Q9NUM4,Q13501,Q9H9P8,P21964,O00192,P22626,Q92673,Q7LGA3,P05067,P53701 12 +Calf muscle pseudohypertrophy 0.7569841600753805 1.600462071489714 0.1094961145751267 1.0 0.6865951002203614 5 Q14118,Q9H9S5 2 +Subcutaneous nodule 0.5560318245544652 1.598491795877059 0.1099335698123165 1.0 0.6865951002203614 20 P48735,Q13510,P06280,P01889 4 +Joint swelling 0.6861686527544345 1.5980308050549217 0.110036121526815 1.0 0.6865951002203614 8 P14174,Q13510 2 +Emg abnormality 0.453052001542771 1.5966219456532016 0.1103500040299436 1.0 0.6865951002203614 94 O14773,Q14126,P31483,Q04446,P15289,Q13501,Q9BUK6,Q13510,Q04656,P51114,P13473,O15269,P07602,P50402,Q13049,Q9NQ11,Q9H9S5 17 +Broad phalanx of the toes 0.6991460699619172 1.5905458004424802 0.1117118304012181 1.0 0.6865951002203614 7 O14936,Q7LGA3 2 +Mandibular aplasia 0.6989746596701355 1.5897867371384888 0.1118828844328827 1.0 0.6865951002203614 7 P53701 1 +Abnormal lumbar spine morphology 0.6041477370347224 1.58899095958107 0.112062433751962 1.0 0.6865951002203614 14 O00754,P08236 2 +Abnormal diaphysis morphology 0.4434165920391082 1.588079000867691 0.1122684761013224 1.0 0.6865951002203614 88 Q04721,O00754,P16278,P34059,O75718,Q32P28,Q8WVQ1,Q04656,Q9NX62,P22694,Q9Y619,Q7LGA3,Q9Y487,P08236,P51798 15 +Generalized hyperkeratosis 0.7534421273435203 1.585745972818965 0.1127969459039497 1.0 0.6865951002203614 5 P04066 1 +Hypocholesterolemia 0.6974902358912513 1.5832111960597828 0.1133733354389627 1.0 0.6865951002203614 7 Q15800,P07602 2 +Type ii lissencephaly 0.8004137350859302 1.5815010413917563 0.1137635210227965 1.0 0.6865951002203614 4 O43505,Q9H9S5 2 +Eeg with abnormally slow frequencies 0.531604151895116 1.5788207197698134 0.1143771846659997 1.0 0.6865951002203614 23 Q9NUM4,Q13501,Q9H2C2,P11166,O75503 5 +Abnormal left ventricle morphology 0.4859989546803531 1.5780273703099592 0.1145593220498846 1.0 0.6865951002203614 35 Q07021,O75787,P10253,P00533,P06280,Q9H9S5 6 +Abnormality of the extraocular muscles 0.7994341730397037 1.5775455326571313 0.1146700538271447 1.0 0.6865951002203614 4 Q9BVA1,Q7LG56 2 +Biliary tract abnormality 0.5080581602156468 1.577101072507079 0.1147722704851765 1.0 0.6865951002203614 30 P14174,P15289,P04062,P07602,Q14108 5 +Abnormality of the larynx 0.4656635142385358 1.576862693817388 0.1148271221897523 1.0 0.6865951002203614 56 P35637,Q92804,Q13501,P21964,Q13510,Q5SZK8,P07602,Q68CQ7,Q9UBM7 9 +Myoclonic seizure 0.4596551705800696 1.573804272301203 0.1155327060642861 1.0 0.6865951002203614 59 P16278,Q13510,P04062,P07686,Q9Y619,P07602,Q8NHS3,P11166,O75503,Q99519 10 +Asymmetric septal hypertrophy 0.9476088124664148 1.5733063114293744 0.1156479086320509 1.0 0.6865951002203614 3 P54802,P15586 2 +Wide anterior fontanel 0.5071358137998405 1.5704121354978715 0.11631926100736 1.0 0.6865951002203614 30 O75718,Q08J23,Q32P28,Q9Y487,P98164 5 +Episodic ataxia 0.6945921207037004 1.5703631460825216 0.1163306512176256 1.0 0.6865951002203614 7 O14936,P11166 2 +Acute phase response 0.5028551108570338 1.5687400788231736 0.1167085157245026 1.0 0.686992074458215 31 P02792,P14174,P01889,P15260,O15460,P10644,P41440,Q9UBC1 8 +Skin ulcer 0.4891282296994113 1.5651032704974777 0.1175586968575328 1.0 0.6902730456827738 34 Q04721,Q04446,P01889,Q03519,O75874,O15460,Q8IZA0,P04062,O15269,P48735 10 +Prolonged neonatal jaundice 0.5367487968122818 1.5642581839427507 0.1177569480459677 1.0 0.6905771269113653 22 O15118,P61916,Q15904,Q04656 4 +Vestibular dysfunction 0.4832282984624646 1.557597568688042 0.1193286754094073 1.0 0.6973150894030521 36 O43405,P01889,P10644,P06280,P41440,Q15043 6 +Intrinsic hand muscle atrophy 0.7462444387193049 1.5557987222956238 0.1197559620709505 1.0 0.6973150894030521 5 Q13501 1 +Macular atrophy 0.6911325357580262 1.5550083689641605 0.1199440761702508 1.0 0.6973150894030521 7 P04439 1 +Abnormality of the tongue 0.4648333922184049 1.5543999458683506 0.1200890461495818 1.0 0.6973150894030521 105 P01889,Q7LGA3,P16278,Q13510,Q5SZK8,P10253,O15460,P07686,P67870,Q9NQ11,Q9UBM7,Q9H9B1,Q9Y5Y5,O75844,P04066,Q99519,O00754,O95831,P51114,Q9H9S5,Q05086 21 +Leg muscle stiffness 0.7929659052173976 1.5514077322397002 0.120804003394614 1.0 0.7006037835247297 4 O00592 1 +Agyria 0.7446573643684405 1.5491879090174416 0.121336555163414 1.0 0.7014689287560746 5 Q14118 1 +Abnormal pulmonary valve morphology 0.5475156962311177 1.5456965668589613 0.1221778667861517 1.0 0.7014689287560746 20 P21964,O00192,P10644,O00571,P51798 5 +Urinary incontinence 0.4604014670184475 1.5453468995263262 0.1222623769800428 1.0 0.7014689287560746 57 P35637,P15289,Q13501,P07686,Q06787,O94898,P07602,Q8TAA9,Q92581,Q9NQ11,P11166 11 +Shoulder girdle muscle weakness 0.565056261140018 1.5424665498538357 0.1229602604345543 1.0 0.7014689287560746 17 O14979,P07602,Q9H9S5 3 +Depression 0.4870719877908589 1.5416990131115071 0.1231467518819873 1.0 0.7014689287560746 122 P01889,Q13501,Q6DKK2,P04062,P07602,P06280,Q9UBX1,P50897,P15289,O15460,P10644,P11166,Q9NQ11,Q9H9B1,Q9NUM4,Q08J23,Q9BUK6,P21964,Q68CQ7,P35637,O00754,Q92804,O00592,Q06787 24 +Bifid tongue 0.7900902516563629 1.5397774226737453 0.1236146170752419 1.0 0.7030674541734205 4 Q5SZK8,Q9UBM7 2 +Abnormal protein o linked glycosylation 0.7894726873892944 1.5372789727351104 0.1242250084133615 1.0 0.7048386458110708 4 Q15904,Q8N511 2 +Recurrent hand flapping 0.7883989236193332 1.532934263975098 0.1252920524865324 1.0 0.7057969264922346 4 Q06787,Q05086 2 +Cystoid macular edema 0.74030000257835 1.531024261844195 0.1257633965192606 1.0 0.7076066999860546 5 P04439 1 +Nephropathy 0.5444142627633196 1.526398513131039 0.1269106477281374 1.0 0.7106694822306033 20 P06280 1 +Epiphora 0.7385619411416375 1.5237737801630014 0.1275652315151578 1.0 0.71094190901843 5 Q07954 1 +Limb girdle muscle atrophy 0.5669520036049368 1.5223185151333931 0.127929291007151 1.0 0.71094190901843 16 O14979,Q9H9S5,P50402,Q14118 4 +Flattened epiphysis 0.7377523232495371 1.52039536037198 0.1284116398561661 1.0 0.71094190901843 5 Q8WVQ1 1 +Recurrent joint dislocation 0.9274778404512488 1.5203888775521337 0.1284132682076229 1.0 0.71094190901843 2 Q8NCH0 1 +Abnormal circulating copper concentration 0.7373625924627228 1.5187688393952197 0.1288206919657493 1.0 0.71094190901843 5 Q15904 1 +Aortic dissection 0.737023181893836 1.517352205998324 0.1291777839364394 1.0 0.71094190901843 5 O15460,P01889 2 +Metatarsus valgus 0.9325631380977965 1.5163646296861293 0.129427177628955 1.0 0.71094190901843 3 Q14118,O43505 2 +Abnormality of the autonomic nervous system 0.4245277261058779 1.5158272671972992 0.1295630353396397 1.0 0.71094190901843 71 P42892,Q96EK5,Q04446,P15289,P21964,O00192,Q04656,O00592,P04062,P07686,O15269,P07602,P06280,Q06787,P41440,Q6PJG6,Q9UBM7 17 +Communicating hydrocephalus 0.7364504364037915 1.514961423457739 0.1297821736599211 1.0 0.71094190901843 5 O00754 1 +Primary hypercortisolism 0.7833915614082123 1.51266295680693 0.130365293524131 1.0 0.71094190901843 4 P10644,P17252,P17612 3 +Adrenocortical abnormality 0.7833915614082123 1.51266295680693 0.130365293524131 1.0 0.71094190901843 4 P10644,P17252,P17612 3 +Poor gross motor coordination 0.7356625537558086 1.5116720849277576 0.1306173034905455 1.0 0.71094190901843 5 O75503 1 +Macular thickening 0.6527608889724037 1.510568018056452 0.1308985474861617 1.0 0.71094190901843 9 P04439 1 +Micrographia 0.9303975623950278 1.508164332772337 0.1315124733653805 1.0 0.71094190901843 3 P04062 1 +High frequency sensorineural hearing impairment 0.7344654077636211 1.5066729667153786 0.1318945041021579 1.0 0.71094190901843 5 O75844,Q13510 2 +Optic nerve dysplasia 0.9237174321783564 1.5049979907629665 0.1323245933061858 1.0 0.71094190901843 2 O43505 1 +Absent hypoplastic paranasal sinuses 0.92932438851344 1.5041002680615223 0.1325555513056009 1.0 0.71094190901843 3 P04066 1 +Delayed ability to stand 0.7812480652803175 1.5039804642367076 0.1325863969498297 1.0 0.71094190901843 4 P10253 1 +Delayed fine motor development 0.6381816298061516 1.503658307411097 0.1326693695755882 1.0 0.71094190901843 10 Q5KU26 1 +Cephalohematoma 0.922911630405593 1.501700107760474 0.1331745760633715 1.0 0.71094190901843 2 Q6YHK3 1 +Abnormal foveal morphology 0.7806216242941598 1.5014424483472475 0.1332411617146678 1.0 0.71094190901843 4 Q99519 1 +Broad femoral neck 0.7327198884071298 1.4993814786946478 0.1337746956592076 1.0 0.71094190901843 5 Q8WVQ1 1 +Abnormality on pulmonary function testing 0.5196026223024308 1.499274474583266 0.1338024414380556 1.0 0.71094190901843 23 P16278,P34059,Q9H9S5,P01889 4 +Neonatal alloimmune thrombocytopenia 0.7105116348759656 1.498983068364738 0.1338780245860908 1.0 0.71094190901843 6 Q6YHK3 1 +Abnormal endocardium morphology 0.5518721318747453 1.4976478406759004 0.1342247701441623 1.0 0.71094190901843 18 P04062,P06280,P01889 3 +Hyperthyroidism 0.6093689515126766 1.4953757220593829 0.134816412985669 1.0 0.711986142359772 12 Q06787,P21964,O00192,Q9BUK6 4 +Abnormality of the shoulder girdle musculature 0.4740256500435413 1.4946798759386586 0.134998008752839 1.0 0.711986142359772 40 Q13501,O14979,P07602,Q9Y487,P50402,Q9H9S5 6 +Wormian bones 0.532564560915797 1.4929483143709406 0.1354507168073384 1.0 0.7135755639626825 21 Q04721,O75718,Q32P28,O95831,O75844,Q9Y487 6 +Eeg with spike wave complexes 0.5502565242319994 1.4879406722119002 0.1367665403096842 1.0 0.7164144511690235 18 O14936,Q14108,O75503,P11166 4 +Sepsis 0.5248857378956058 1.4872224611123672 0.136956065652549 1.0 0.7164144511690235 22 P42892,P02786,P01889 3 +Gastrointestinal infarctions 0.9191512221326948 1.4863110640674675 0.1371968615370939 1.0 0.7164144511690235 2 P01889 1 +Recurrent pharyngitis 0.9191512221326948 1.4863110640674675 0.1371968615370939 1.0 0.7164144511690235 2 P01889 1 +Glossitis 0.9191512221326948 1.4863110640674675 0.1371968615370939 1.0 0.7164144511690235 2 P01889 1 +Gonosomal inheritance 0.4188010575324299 1.484606761933005 0.1376480231879528 1.0 0.717138595946075 78 P38159,O95831,Q15904,O75787,Q04656,P13473,Q06787,Q9UPP1,O14936,P06280,P50402,P55795,Q92581,P53701 14 +Omphalocele 0.5841857703272144 1.4808573925620585 0.1386445789340549 1.0 0.7182460691918794 14 P98164 1 +Vitritis 0.9228761331687764 1.4796772672805556 0.1389593951147212 1.0 0.7182460691918794 3 P04439 1 +Abnormal enchondral ossification 0.4728894450715088 1.479228520423809 0.1390792494532737 1.0 0.7182460691918794 38 Q9Y5Y5,Q8WVQ1,P22413,Q7RTS9,P10644,Q9Y619,O00116,P08236,Q9UBM7,Q99519 10 +Subcortical cerebral atrophy 0.7052970308952766 1.4766311381970056 0.1397745401807677 1.0 0.7183629480367233 6 O00754 1 +Tetraplegia tetraparesis 0.4607663909548312 1.4764905871891891 0.1398122402950403 1.0 0.7183629480367233 52 P35637,P15289,O95831,Q13501,P51970,Q13423,P07602,P17900 8 +Shuffling gait 0.6189302307538976 1.4747002861750622 0.1402931391211384 1.0 0.7183629480367233 11 O00592,P04062 2 +Degeneration of the lateral corticospinal tracts 0.6447729097172552 1.473066716769294 0.1407330469428613 1.0 0.7183629480367233 9 Q13501 1 +Aplasia hypoplasia of the femur 0.5579319341232807 1.4701103794946382 0.1415318616542271 1.0 0.7198734926641651 16 Q8WVQ1,P15260 2 +Flared iliac wing 0.7035291994433115 1.469046473798653 0.1418201843604043 1.0 0.7203151002638268 6 P16278 1 +Diastasis recti 0.7719405755500394 1.4662478020582377 0.142580790120393 1.0 0.7203151002638268 4 Q8NCH0 1 +Abnormal coronary artery morphology 0.6572548714013641 1.4661404600099268 0.1426100251163107 1.0 0.7203151002638268 8 P01130,P16278 2 +Hypopigmented skin patches 0.4926712354904171 1.464899700836241 0.1429482844551728 1.0 0.7203151002638268 30 Q8IZA0,P53701,P07602,P53634 4 +Late onset 0.6167469536151098 1.4638111105224714 0.1432455658581128 1.0 0.7203151002638268 11 P31751,P43304,P31483,Q9Y6M1 4 +Acute hepatic failure 0.5566311302822995 1.4625600091343165 0.1435878127160057 1.0 0.7203151002638268 16 P38571,P01889 2 +Recurrent sinopulmonary infections 0.6423398607840882 1.4616217840235262 0.1438448815034607 1.0 0.7203151002638268 9 P02786 1 +Widely spaced teeth 0.4705911596485868 1.4565857693165971 0.1452307582389385 1.0 0.7203151002638268 35 P16278,P34059,P08236 3 +Restless legs 0.6688716906060445 1.4557730069510468 0.1454553800720637 1.0 0.7203151002638268 7 O00592 1 +Hypoglycemic seizures 0.6688047091249758 1.455473340175966 0.1455382655894785 1.0 0.7203151002638268 7 Q13423 1 +Impairment of activities of daily living 0.4130337954517608 1.4553436031893736 0.1455741610543 1.0 0.7203151002638268 73 P35637,P15289,Q13501,P21964,P07686,O15269,O94898,P07602,Q06787,Q8TAA9,Q92581,Q9NQ11,P11166 13 +Decreased muscle mass 0.5265683179099095 1.4546286755414102 0.1457720879371946 1.0 0.7203151002638268 21 Q92581,P04066,Q9Y487,Q8NCH0 4 +Social and occupational deterioration 0.9113618049959782 1.4544418966882038 0.1458238313695743 1.0 0.7203151002638268 2 Q9BQE5 1 +Negativism 0.9113618049959782 1.4544418966882038 0.1458238313695743 1.0 0.7203151002638268 2 Q9BQE5 1 +Abnormal oral physiology 0.4239325779084577 1.4521058685009347 0.146472170443433 1.0 0.7203151002638268 69 P35637,Q8N0X7,Q02241,Q92804,P08754,P01889,Q13501,O75787,O15460,P10644,P15586,P55011,P55795,Q68CQ7,Q92581,Q05086 16 +Encephalocele 0.5256554779306071 1.4487826379620443 0.147398293885095 1.0 0.7203151002638268 21 P14543,O43505,Q5SZK8 3 +Abnormality of the metacarpal bones 0.454679207785569 1.4478816302087032 0.147650157961338 1.0 0.7203151002638268 54 P16278,P34059,Q32P28,Q9NX62,P10644,P08236,P51798 7 +Tetraplegia 0.5660699007703416 1.4461578600847342 0.1481329301169922 1.0 0.7203151002638268 15 O95831,Q13423,P15289 3 +Eeg with focal spike waves 0.9138099260143276 1.4453317521548006 0.1483647231992568 1.0 0.7203151002638268 3 Q14118 1 +Abnormal cervical spine morphology 0.697813375721529 1.4445000668288928 0.148598360949784 1.0 0.7203151002638268 6 P04066 1 +Waddling gait 0.4776768849676085 1.442456122144472 0.1491737412534748 1.0 0.7203151002638268 33 Q4J6C6,Q8WVQ1,Q13510,P22626,Q14118,P50402,Q13049,Q9H9S5 8 +Tricuspid atresia 0.7189455728579675 1.4417473283163655 0.1493736667277994 1.0 0.7203151002638268 5 P21964 1 +Multiple suture craniosynostosis 0.7189455728579675 1.4417473283163655 0.1493736667277994 1.0 0.7203151002638268 5 P21964 1 +Cervical subluxation 0.9127904038174368 1.4414692821714676 0.1494521494488623 1.0 0.7203151002638268 3 P16278 1 +Small earlobe 0.6518380548904099 1.4412799374100984 0.1495056128727083 1.0 0.7203151002638268 8 P10586,P21964,O00192 3 +Abnormality of the lymphatic system 0.544400448268443 1.441033692025673 0.1495751645965841 1.0 0.7203151002638268 176 P14174,P01889,P15260,Q16625,Q15904,P23458,P04062,P07602,P15586,P16278,P54802,P61916,Q13510,O15460,P10253,P07686,P10644,Q96J02,P08236,P38571,P11166,P10619,Q14108,P51798,Q86WC4,P51688,Q15392,P21964,P13051,O14936,P48735,P04066,Q99519,Q04721,O00754,O15118 36 +Broad ribs 0.6966786816554297 1.439623037111291 0.1499740783319327 1.0 0.7204919934273096 6 P16278,Q04656 2 +Increased circulating cortisol level 0.7178758605029947 1.4372648670118573 0.1506427476259784 1.0 0.7210970102096327 5 P10644,P17252,P17612 3 +Abnormal arterial physiology 0.4848264774271619 1.4350644225011189 0.1512687405625314 1.0 0.7230805928598666 31 P01889,O15460,O75844,P06280,P05067 5 +Movement abnormality of the tongue 0.7631615106851637 1.4306163385353046 0.1525402022471444 1.0 0.7230805928598666 4 Q9NQ11,P10253 2 +Pneumonia 0.4403472187150481 1.4295096317243612 0.1528578085827339 1.0 0.7230805928598666 61 O00754,P16278,P15260,Q13510,Q86WC4 5 +Follicular hyperkeratosis 0.6492752184814692 1.4295023791483636 0.1528598916087529 1.0 0.7230805928598666 8 Q14574,Q07954 2 +Abnormality of female external genitalia 0.465945879221925 1.428718766174931 0.1530850818139906 1.0 0.7230805928598666 40 Q15392,Q08J23,Q5SZK8,P10644,Q9Y619,P51809,P53701 7 +Abnormal pulmonary thoracic imaging finding 0.5038476101035521 1.428585637864105 0.1531233645293095 1.0 0.7230805928598666 25 P15260,Q13510,P01889 3 +Rimmed vacuoles 0.5403334075257301 1.4281221546024052 0.1532567017618065 1.0 0.7230805928598666 18 Q13501,O14979,P31483,P50402 4 +Abnormal thalamic size 0.7609090483835779 1.421468865359622 0.1551804986513631 1.0 0.7230805928598666 4 Q9H9S5 1 +Abdominal aortic aneurysm 0.7607333790278541 1.420755371090712 0.1553878891011089 1.0 0.7230805928598666 4 P01889 1 +Retinal dystrophy 0.4351299575598339 1.4195153339128477 0.1557488296077078 1.0 0.7230805928598666 63 Q9Y5Y5,O43505,Q9Y287,Q14118,Q9H2C2,Q9H9S5,Q8NHS3,P98164,P53701 9 +Hyperkeratosis 0.4233347738048317 1.4191695919823355 0.1558495788590583 1.0 0.7230805928598666 68 Q9P265,Q14126,P53634,Q14574,Q9NWM8,O75844,P04062,O15269,P06280,O95721,Q06136,Q07954,P04066,Q99519 14 +Happy demeanor 0.7603077945373455 1.4190267791534712 0.1558912089689919 1.0 0.7230805928598666 4 Q92581 1 +Frontal lobe dementia 0.7135135937755812 1.418976500947409 0.1559058671340838 1.0 0.7230805928598666 5 O00592 1 +Tongue fasciculations 0.5836548069135666 1.4174341847881589 0.1563560240010899 1.0 0.7230805928598666 13 O95831,Q13510 2 +Anarthria 0.6323900072648347 1.4147135701905869 0.1571524939764228 1.0 0.7230805928598666 9 O00592,P02792,Q9NQ11 3 +Wide intermamillary distance 0.4958459643556938 1.413750265650949 0.1574352409268491 1.0 0.7230805928598666 27 Q96EK5,P61978,Q8WWQ0,Q5SZK8,P23786,O14678,P07437,Q9UBM7 8 +Abnormal caudate nucleus morphology 0.5935068050024855 1.4137036538006515 0.1574489321022798 1.0 0.7230805928598666 12 P02792,Q9NQ11,O75306 3 +Long toe 0.6195045904019948 1.4131596577999883 0.1576087853243208 1.0 0.7230805928598666 10 P10644,P23786 2 +Lipoma 0.6593526030502739 1.4131262245020046 0.1576186137081674 1.0 0.7230805928598666 7 Q9BUK6 1 +Amyloidosis 0.7584140985063287 1.4113343635218072 0.1581460465753441 1.0 0.7230805928598666 4 Q9Y287 1 +Abnormality of the supraorbital ridges 0.501329904109832 1.411269317940452 0.1581652178007948 1.0 0.7230805928598666 25 Q9Y5Y5,Q9UPP1,Q99519,Q08J23 4 +Arthralgia 0.4608211439473708 1.4112352988019017 0.1581752451409035 1.0 0.7230805928598666 45 Q04721,P01130,P02792,P14174,P01889,Q13510,O15460,P06280 8 +Pericardial effusion 0.6588062776266641 1.4106750791871057 0.1583404423990488 1.0 0.7230805928598666 7 Q14108 1 +Eeg with generalized slow activity 0.6060456617191112 1.4102961880138507 0.1584522436571747 1.0 0.7230805928598666 11 Q13501,O75503 2 +Intellectual disability progressive 0.5425751648918066 1.409703300050442 0.1586273099068806 1.0 0.7230805928598666 17 O95831,Q9H9P8,O95721,Q92581,Q05086,P53701 6 +Hyperextensible skin 0.5314890629183839 1.408451509061793 0.1589974160143368 1.0 0.7230805928598666 19 Q9H9B1,Q8NCH0,Q04656,P04062,O94766 5 +Xanthelasma 0.9000805801772875 1.4083175546122424 0.15903705983016 1.0 0.7230805928598666 2 P01130 1 +Tendon xanthomatosis 0.9000805801772875 1.4083175546122424 0.15903705983016 1.0 0.7230805928598666 2 P01130 1 +Loss of voice 0.903906795137369 1.4078148298965454 0.1591859079107136 1.0 0.7230805928598666 3 Q13510 1 +Bruising susceptibility 0.464375337687117 1.407161742227155 0.1593794332398233 1.0 0.7230805928598666 35 P22413,Q86YV9,P51798,Q9NWM8,Q8NCH0,P04062,P10644,Q04656,P17612,Q15833,Q14108 11 +Parkinsonism with favorable response to dopaminergic medication 0.5919369147885448 1.4055899313691238 0.1598459275844781 1.0 0.7230805928598666 12 P04062,P07602 2 +Posterior fossa cyst 0.7569591536843179 1.4054233466682509 0.1598954283476139 1.0 0.7230805928598666 4 Q12768,Q9H9S5 2 +Intracellular accumulation of autofluorescent lipopigment storage material 0.9018394091483192 1.3999836094012263 0.1615182267694859 1.0 0.7241950825261462 3 O14773 1 +Ankle clonus 0.5457202356513303 1.399023653014091 0.1618058902511905 1.0 0.7241950825261462 16 Q8N0X7,O75787,P07602,Q9NP72,Q15043 5 +Unusual infection by anatomical site 0.5355116448538688 1.3989362162939396 0.1618321110135219 1.0 0.7241950825261462 18 P01889,Q9H9P8,O15460,P02786,Q8TAA9,Q15833 6 +Hyperhidrosis 0.467347490499243 1.395560257226971 0.1628469573759448 1.0 0.7250457072970535 34 P07686,P07858,P04066,P01889 4 +Abnormal waist to hip ratio 0.6410745006151835 1.3917521650589553 0.1639974597795819 1.0 0.726280735199417 8 P43304,P31751,Q9Y6M1 3 +Atlantoaxial abnormality 0.7068119446426996 1.3908542679972922 0.1642696229532709 1.0 0.726280735199417 5 Q7RTS9,Q8NCH0,Q9NWM8 3 +Heterogeneous 0.449723159556863 1.3901840529763858 0.1644729946828387 1.0 0.726280735199417 53 Q9BQE5,Q14126,P53634,P01889,P61916,P21964,O75844,Q9Y619,P11717,P05067,P51798 11 +Hyposmia 0.5163085385985845 1.3887376423468891 0.1649125433057883 1.0 0.726280735199417 21 O00592,P04062,O60266,Q9NQ11,Q15043 5 +Abnormality of cartilage of external ear 0.705613305715209 1.3858212952904423 0.1658014781277725 1.0 0.7292481057578802 5 P22413,Q7LGA3,P08754 3 +Thick lower lip vermilion 0.4504361703260686 1.3845553467476843 0.1661884733404881 1.0 0.7302690137934778 52 Q9H9B1,Q9Y619,P06280,P15586,P11166,P04066,Q99519 7 +Abnormality of the parathyroid gland 0.5090672600648973 1.38358893857349 0.1664843572324494 1.0 0.7303228041076077 22 Q08J23,P21964,O00192,P10644,P48735,P29992 6 +Corpus callosum atrophy 0.5430643322284481 1.383503609078139 0.1665105014667398 1.0 0.7303228041076077 16 O00754,Q9Y5Y5,Q9H9P8,P51970,O75503 5 +Fingerprint intracellular accumulation of autofluorescent lipopigment storage material 0.8928283642224146 1.37869437494212 0.1679890045669045 1.0 0.733480942299134 2 O75503 1 +Central apnea 0.6246561547465936 1.378141878945864 0.1681594877364025 1.0 0.733480942299134 9 P07602 1 +Abnormal hypothalamus morphology 0.7495980567327547 1.37550742355433 0.168974185826733 1.0 0.7344923720350269 4 P19022,P35222 2 +Hyperkinetic movements 0.5649000510229918 1.3753630339430565 0.1690189233633094 1.0 0.7344923720350269 14 P07602 1 +Abnormality of facial musculature 0.4292780392505351 1.374018717871396 0.1694358715151707 1.0 0.7350271122962345 92 O00754,P02792,Q9Y5Y5,Q13501,Q9BUK6,O75787,Q13510,P10253,O00592,P04062,Q9NQ11,P51798,Q15043,Q9H9S5 14 +Abnormal circulating long chain fatty acid concentration 0.7013219984631576 1.3677954037457931 0.1713761268188172 1.0 0.73673826897231 5 P23786 1 +Abnormality of primary teeth 0.5354508723139797 1.3672920951957794 0.1715337684192497 1.0 0.73673826897231 17 Q9H9B1,P51798,P53634 3 +Adrenal overactivity 0.6797902026602641 1.3668870706252751 0.1716607052316667 1.0 0.73673826897231 6 P10644,P17252,P17612 3 +Vascular tortuosity 0.8926987773292592 1.365366784458388 0.1721377981186322 1.0 0.7375060181715336 3 P05067 1 +Protuberant abdomen 0.6485567952284788 1.3646232226094952 0.1723715020201548 1.0 0.7375060181715336 7 P04062,Q7RTS9,P42345,P38571 4 +Brain imaging abnormality 0.4564817815409247 1.3629018861127242 0.172913434220636 1.0 0.7382227316969402 43 Q9H9B1,Q9NUM4,Q13501,O75306,O00429,Q00577,Q9P0J1,P07602,Q969X5,P11166,Q92560,Q05086,P35610,Q93009 14 +Generalized onset motor seizure 0.4370854131872358 1.3618255665799774 0.1732529409904695 1.0 0.7385963985262782 59 P16278,Q13510,P04062,Q9Y619,O14936,P67870,P07602,Q05086,P11166,Q92581,Q8NHS3,Q99519 12 +Spastic paraparesis 0.4931545374849891 1.354846337035065 0.1754665198823639 1.0 0.7424323758690577 25 Q8N0X7,Q9Y5Y5,Q6DKK2,O75787,P04062,Q9Y619,Q9H6K4 7 +Broad palm 0.6320811643761186 1.3502482241120413 0.1769363741968708 1.0 0.7446339784140618 8 O95831,P10644 2 +Abnormality of the musculature of the lower limbs 0.4614235825867174 1.348947070289846 0.1773539677113449 1.0 0.7446339784140618 34 O14979,O00592,Q14118,P50402,Q9NQ11,Q9H9S5 6 +Increased muscle glycogen content 0.7420002248993123 1.3446162728989914 0.1787491855054157 1.0 0.7473823691107611 4 Q9BUK6 1 +Motor deterioration 0.6737585884764447 1.3408498181597073 0.1799692177370184 1.0 0.7489451558958888 6 O75503 1 +Congenital hypothyroidism 0.7407989659423602 1.3397313985029016 0.1803326857074096 1.0 0.7497291498819035 4 Q13423 1 +Long thorax 0.740690916851708 1.3392920131564428 0.1804756278082631 1.0 0.7497291498819035 4 P17612,P22694 2 +Cachexia 0.5083086862841796 1.337086073984072 0.1811945423368337 1.0 0.751820893900239 21 P04062,Q92581,P07602,P38571 4 +Status epilepticus 0.4423098709823876 1.3356289418749154 0.1816705854845086 1.0 0.751820893900239 54 Q9H9B1,P42892,Q15392,P51970,Q13510,Q9H2C2,P07602,Q9Y487,P53701 9 +Toe walking 0.4875238694789264 1.334421921585891 0.1820656196569154 1.0 0.751820893900239 26 P15289,O95831,P07602,P50402,Q9H9S5 5 +Ventricular hypertrophy 0.4517340471626762 1.333932093738343 0.1822261123650099 1.0 0.751820893900239 45 Q07021,O75787,P23786,P10253,O75844,P00533,P06280,Q9H9S5 8 +Rheumatoid arthritis 0.8802041364491069 1.327201695730234 0.1844419716161907 1.0 0.7562707205575686 2 P14174 1 +Poor motor coordination 0.5322220290114041 1.3199354715381475 0.1868565632855632 1.0 0.7591572425630421 16 Q06787,O75503,Q9H9S5 3 +Abnormal circulating non proteinogenic amino acid concentration 0.6683531775449828 1.317492870181013 0.1876734694048665 1.0 0.7611692479651646 6 P05067 1 +Morphological abnormality of the pyramidal tract 0.4901279617227125 1.3167621791336095 0.1879183539688844 1.0 0.7611692479651646 24 O95831,Q13501,Q9Y619,P11166 4 +Melena 0.6376703818513133 1.3155825497036142 0.1883141937234409 1.0 0.7611692479651646 7 P17301,Q6YHK3 2 +Abnormal thyroid stimulating hormone level 0.8788285867812986 1.3128792471437012 0.1892236408998571 1.0 0.7619038999511754 3 P16870,P10644 2 +Difficulty in tongue movements 0.8785599140247156 1.3118632153886391 0.1895662908719988 1.0 0.7619821495835247 3 Q9NQ11,P10253 2 +Dilatation of the cerebral artery 0.5735246759087618 1.310048653358024 0.1901793769991582 1.0 0.7637953684421047 12 P10253 1 +Proximal muscle weakness 0.4012932662024572 1.3093788359209435 0.1904060568804375 1.0 0.7640549431415005 77 P35637,Q13501,Q9BUK6,Q13510,P10253,P51114,P13473,Q14118,P50402,Q13049,Q9H9S5 11 +Abnormal upper motor neuron morphology 0.5848022151214394 1.3034148726761154 0.1924331616603571 1.0 0.7702227141159458 11 P35637,Q13501 2 +Buphthalmos 0.6857115236155852 1.3021446111989896 0.1928669554195812 1.0 0.7705430218301769 5 Q14118 1 +Generalized myoclonic seizure 0.4491889947658986 1.297135379477067 0.1945846102048152 1.0 0.7745261209744219 42 P16278,Q13510,P04062,Q9Y619,P07602,Q8NHS3,Q99519 7 +Weakness of long finger extensor muscles 0.8741819798103425 1.2953118160259338 0.1952126846733484 1.0 0.7745261209744219 3 Q13501 1 +Renal dysplasia 0.5184112870707884 1.2948325381291477 0.1953780047199291 1.0 0.7745261209744219 18 O14936,O43505,Q9H9S5,P09471 4 +Poor head control 0.408568251977883 1.2914655854639028 0.1965422811436219 1.0 0.7745261209744219 83 P09471,P06865,O43676,P51970,Q9NWM8,Q5KU26,Q14118,Q9H2C2,P07602,O96000,O14936,O95721,P17900 13 +Sparse lateral eyebrow 0.6192196740702093 1.2907216536179758 0.196800213333701 1.0 0.7745261209744219 8 P61978,Q00577,Q08J23 3 +Abnormality of the radioulnar joints 0.7284230497416299 1.2894012932673145 0.1972586120496444 1.0 0.7745261209744219 4 Q8WVQ1,Q96L58 2 +Radioulnar dislocation 0.7284230497416299 1.2894012932673145 0.1972586120496444 1.0 0.7745261209744219 4 Q8WVQ1,Q96L58 2 +Corneal neovascularization 0.6618362778171376 1.2893078446626034 0.1972910848442028 1.0 0.7745261209744219 6 P21964 1 +Pleural effusion 0.5595542460665919 1.2886849642904028 0.1975076317706052 1.0 0.7745261209744219 13 P01889 1 +Ascending tubular aorta aneurysm 0.6612969196378929 1.2869740516794987 0.1981033325568941 1.0 0.7745261209744219 6 O75844,P01889 2 +Airway obstruction 0.516635637870868 1.2839720691770509 0.1991517284785171 1.0 0.7745261209744219 18 O75844,P21964,P06280 3 +Thickened calvaria 0.5929952051380446 1.2836689045963714 0.1992578289996336 1.0 0.7745261209744219 10 P16278 1 +Mitral valve calcification 0.7269963733852806 1.2835996472554738 0.1992820732457458 1.0 0.7745261209744219 4 P04062 1 +Cardiac valve calcification 0.7269963733852806 1.2835996472554738 0.1992820732457458 1.0 0.7745261209744219 4 P04062 1 +Symptomatic seizures 0.6175882315079176 1.2831579082955842 0.1994367592414725 1.0 0.7745261209744219 8 Q13423 1 +Jaundice 0.4148309849127953 1.2829276715176603 0.1995174172014124 1.0 0.7745261209744219 66 Q9Y5Y5,P61916,Q16625,Q15904,O75787,Q04656,P10644,P38571,P11166,O15118 10 +Vertigo 0.4680648883102346 1.282852779465497 0.1995436589802917 1.0 0.7745261209744219 30 P10644,O43405,P06280,P01889 4 +Abnormality of salivation 0.4364980692844037 1.2824700613513829 0.1996778007488913 1.0 0.7745261209744219 54 P35637,Q8N0X7,Q92804,P01889,Q13501,O75787,P15586,P55795,P55011,Q68CQ7,Q92581,Q05086 12 +Postural instability 0.4849522284745201 1.2812319764495552 0.2001121976790867 1.0 0.7745261209744219 24 O00592,P04062,O75503,P41440 4 +Ocular pain 0.7262396801621254 1.280522613049078 0.2003613970562265 1.0 0.7745261209744219 4 P29992,Q15043 2 +Muscle fibrillation 0.5159741674873698 1.279923972604339 0.2005718756542458 1.0 0.7745261209744219 18 O95831,Q13510 2 +Corneal erosion 0.6591833122469509 1.2778270064835813 0.2013104297717838 1.0 0.7748847696654674 6 P01889 1 +Hypohidrosis 0.5574649357646819 1.2774662531238374 0.2014376872862275 1.0 0.7748847696654674 13 P07686,P06280 2 +Aplasia hypoplasia involving the pelvis 0.5153685938918677 1.276216860511589 0.201878870089631 1.0 0.7753427150176158 18 Q8WVQ1,P15260 2 +Lissencephaly 0.4204897842084811 1.275232533484627 0.2022269493131769 1.0 0.7758340651030344 63 Q86XL3,O43505,Q96EK5,P09471,Q15392,Q16625,P23786,Q14118,O14936,O00459,Q9Y487,O95721,Q9H9S5,P98155 14 +Abnormal social behavior 0.398158547290099 1.2746890834416464 0.2024193122548037 1.0 0.7759406969767475 77 P15289,O43676,Q5KU26,O00592,Q92673,P07602,P05067 7 +Neoplasm of the tracheobronchial system 0.6784159874321988 1.271432320062067 0.2035748906807901 1.0 0.7776336754663157 5 P00533 1 +Hyperkalemia 0.6783521248561766 1.271163418903228 0.2036705175066147 1.0 0.7776336754663157 5 Q13423 1 +Aplasia hypoplasia involving the skeletal musculature 0.5559638249467012 1.2694007477352975 0.2042981696415418 1.0 0.7776336754663157 13 Q14118,O43505,Q9H9S5 3 +Gowers sign 0.5142340093457421 1.2692685275355997 0.2043453072964507 1.0 0.7776336754663157 18 Q14118,Q9BUK6,Q13510 3 +Conical tooth 0.6007952160798252 1.2647696437400184 0.2059539162423229 1.0 0.7812330772989161 9 P17252,P22694,Q9Y487,P17612,O60716 5 +Bone fracture 0.6133062231067068 1.263292961661843 0.2064839147260069 1.0 0.7816678928943704 8 Q13501 1 +Recurrent gastroenteritis 0.6764288300497596 1.263064794285136 0.2065658949197 1.0 0.7816678928943704 5 O00754 1 +Abnormality of the nasal bone 0.7214982198430427 1.261243837801448 0.2072210088455113 1.0 0.7831395523101192 4 P10644,P35222 2 +Elevated circulating alanine aminotransferase concentration 0.5543108001915884 1.260514092130972 0.207483967511195 1.0 0.7831395523101192 13 Q15904,P10253 2 +Abnormal pupillary function 0.5881073860224564 1.259678742814984 0.207785276763512 1.0 0.7831395523101192 10 Q92560,P29992,P07602 3 +Pulverulent cataract 0.8630136986301485 1.257290191797778 0.2086485742994683 1.0 0.7838868747585604 2 P02792 1 +Abnormal blood transition element cation concentration 0.5749052511355348 1.2533598074008307 0.2100747917820875 1.0 0.7845192785355308 11 Q15904,Q9Y487,Q02241 3 +Absent epiphyses 0.5982124175416258 1.2524550748064114 0.2104040886121549 1.0 0.7845192785355308 9 Q8WVQ1,Q7LGA3 2 +Gaze evoked nystagmus 0.5527593746059611 1.2521690317847616 0.2105082777764826 1.0 0.7845192785355308 13 P98155,Q9NWX6,P41440 3 +Peripheral opacification of the cornea 0.8627266472263674 1.252050579969025 0.2105514339476673 1.0 0.7845192785355308 3 P01130 1 +Abnormal systemic blood pressure 0.4446037244157483 1.2519362930179398 0.2105930787791017 1.0 0.7845192785355308 111 P01889,P04062,P00533,P07602,P06280,Q8TAA9,P15289,P07686,P10644,Q96J02,O94898,P38571,P01130,P21964,Q04656,Q13423,O75844,P42892,Q04721,Q06787,Q13049 21 +Goiter 0.5622717223419634 1.25134020929947 0.2108103813295736 1.0 0.7845192785355308 12 O75874,Q9UNW1,Q14145,Q7LG56,P48735 5 +Abnormal substantia nigra morphology 0.8616756726918771 1.2480855417829022 0.2119997324538107 1.0 0.7845192785355308 3 P04062 1 +Subarachnoid hemorrhage 0.861364455113387 1.2469115459076516 0.2124299327295624 1.0 0.7845192785355308 3 Q6YHK3 1 +Wide pubic symphysis 0.859790491539094 1.2442151419892915 0.2134203923264386 1.0 0.7867686863324996 2 Q5SZK8 1 +Atlantoaxial instability 0.8597904915390787 1.244215141989229 0.2134203923264617 1.0 0.7867686863324996 2 Q9NWM8 1 +Recurrent respiratory infections 0.4892003156456602 1.2419041167904168 0.2142719410009039 1.0 0.7878866550828502 146 P14174,P01889,P04062,P00533,P07602,Q9Y487,P15586,P16278,P34059,P54802,P53634,Q13510,O00462,P10253,O15460,P08236,P51798,Q9H9B1,P51688,P13051,P02786,P04066,Q04721 23 +Death in infancy 0.4012717205912522 1.2409376453567094 0.214628784571522 1.0 0.7878866550828502 70 P16278,O75718,Q15904,Q5SZK8,P51114,P04062,P07602,P38571,Q9Y6N7 9 +Babinski sign 0.4296702899724675 1.2399330093376812 0.2150001733202027 1.0 0.7878866550828502 101 P35637,O14773,O00754,P02792,P15289,O95831,Q13501,O75787,Q15043,P07602,Q9NQ11,P41440,Q9H6K4,Q9UBX1,P11166 15 +Abnormal facial expression 0.4399101983704425 1.2384488096834585 0.2155496919046775 1.0 0.7878866550828502 46 P02792,Q9BUK6,O75787,Q04656,O00592,P04062,Q06787,Q15043,Q13049,Q9NQ11,Q9H9S5 11 +Abnormality of skin adnexa physiology 0.4371523341732325 1.2363170592203108 0.216340732445891 1.0 0.7878866550828502 49 P07858,P01889,O15460,P07686,O15269,P06280,P04066 7 +Areflexia of lower limbs 0.461591059094472 1.234454289661859 0.2170336697399095 1.0 0.7878866550828502 30 Q9NZJ4,Q13501,O75787,Q7LG56,Q9H6K4 5 +Cholestasis 0.4044464677171318 1.229946914511015 0.2187169844678467 1.0 0.7878866550828502 84 Q04721,Q9Y5Y5,P61916,Q16625,Q15904,Q13510,O75787,Q04656,O75845,P10644,O14936,P38571,P11166,O15118 14 +Round face 0.4772490603273539 1.2281585892001103 0.2193874405915299 1.0 0.7878866550828502 24 O75718,P08754,Q32P28,Q8WVQ1,P10644,P16870 6 +Abnormality of the anterior fontanelle 0.4409700831875258 1.2278864226898798 0.2194896070123453 1.0 0.7878866550828502 42 Q9Y5Y5,O75718,Q32P28,Q08J23,Q9Y619,Q9Y487,P98164 7 +Shoulder girdle muscle atrophy 0.6676980682543991 1.226295524508524 0.2200874849417018 1.0 0.7878866550828502 5 Q9H9S5 1 +Arterial thrombosis 0.6177244818914276 1.22545589715015 0.2204034972633386 1.0 0.7878866550828502 7 P01889 1 +Scarring 0.4417917698305637 1.2250828772999076 0.2205439958951405 1.0 0.7878866550828502 37 P04439,P53634,Q92542,Q9HCM3,Q07954 5 +Distal upper limb muscle weakness 0.6042130353897646 1.2210533416622362 0.2220658240195003 1.0 0.788538852996917 8 Q13501 1 +Vocal cord paresis 0.7113428081271853 1.219970649588717 0.2224760014341649 1.0 0.7892959719805022 4 P43243 1 +Increased intracranial pressure 0.4779494517665243 1.2184431107699738 0.2230556309248714 1.0 0.7907573682787736 23 P07602,P01889 2 +Patellar dislocation 0.475577711369949 1.216613960065719 0.2237511287535476 1.0 0.7908445068013322 24 Q04721,Q8WVQ1,P21964,Q9NX62,P22694 5 +Abnormality of the knee 0.4382072138588145 1.2126231052713592 0.2252739509400345 1.0 0.794600079551878 109 Q04721,O00754,Q86XL3,P16278,P34059,Q8WVQ1,O95831,P21964,Q13510,P23786,Q9NX62,P22694,Q04656,Q9Y619,Q7LGA3,P08236,P51798 17 +Cervical myelopathy 0.85158214919776 1.2100462440971844 0.2262611485851291 1.0 0.794600079551878 3 P16278 1 +Impaired mastication 0.6014601696180962 1.2082527281837083 0.2269500654747944 1.0 0.794600079551878 8 O15460,P01889 2 +Telangiectasia 0.43864559181356 1.208224878934868 0.2269607745779134 1.0 0.794600079551878 42 Q8IZA0,P10619,P06280 3 +Hashimoto thyroiditis 0.7084230497831323 1.2081111303324077 0.2270045190151388 1.0 0.794600079551878 4 Q96J02,Q15437 2 +Abnormal pulmonary interstitial morphology 0.4394869895746778 1.2062307379322268 0.2277285351227069 1.0 0.7947197598186586 36 Q8IZA0,P04062,Q14108,Q13510 4 +Abnormal liver physiology 0.6627554486567728 1.2054790024493658 0.2280184392244424 1.0 0.7947197598186586 5 Q13510 1 +Transient ischemic attack 0.5881414262828739 1.2043716673453375 0.2284459578002728 1.0 0.7949244952238277 9 P06280 1 +Abnormal circulating iga level 0.5030909219283228 1.2008406149873634 0.2298130336722312 1.0 0.796900960662603 18 Q15904,P13051 2 +Aortic regurgitation 0.465964278125044 1.2005581967318677 0.2299226250021544 1.0 0.796900960662603 27 Q9H9B1,O00754,P01889 3 +Abnormal heart valve physiology 0.4189771194180863 1.20016607076911 0.2300748496149482 1.0 0.796900960662603 96 Q9H9B1,P01130,O00754,P16278,P01889,Q15904,O75844,P04062,P10644,P06280,P53701 11 +Aplasia hypoplasia of the capital femoral epiphysis 0.598960262280148 1.1966237442409045 0.2314532413647336 1.0 0.796900960662603 8 Q8WVQ1,Q7LGA3 2 +Lumbar hyperlordosis 0.4808375648641713 1.19626519183003 0.2315930876436172 1.0 0.796900960662603 22 Q14118,P04066,Q9H9S5 3 +Drowsiness 0.6398720753586317 1.194169342767864 0.2324117326958765 1.0 0.796900960662603 6 O00754 1 +Abnormal umbilicus morphology 0.3908991220356881 1.193928689314708 0.2325058639441806 1.0 0.796900960662603 77 Q9H9B1,O00754,Q04721,P09471,P21964,Q5SZK8,Q8NCH0,Q04656,O75844,Q9NWM8,O14936,Q9Y487,P08236,P98164,Q99519 15 +Increased susceptibility to fractures 0.412325198468117 1.19392332958303 0.2325079607033564 1.0 0.796900960662603 63 Q04721,O75718,Q32P28,Q13501,O75845,O75874,Q8WWQ0,P51798,Q04656,P22626,P04062,O15269,P10644,Q9NPE3,P17612,O94766,P48735,Q14108 18 +Occipital meningocele 0.6395689721000456 1.1928554611324598 0.2329259849266647 1.0 0.796900960662603 6 P21964 1 +Decreased circulating antibody level 0.4302206993657429 1.1923059899120676 0.2331412867035758 1.0 0.796900960662603 51 Q8IWT6,O00754,Q9Y2Q5,P14174,Q15477,Q15904,O75787,P13051,Q96J02,P02786,Q15833 11 +Gangrene 0.541609968956037 1.1920733603737237 0.2332324814929678 1.0 0.796900960662603 13 P10644,P01889 2 +Spontaneous hematomas 0.7044337659632968 1.1919138649147327 0.2332950210777675 1.0 0.796900960662603 4 P17301,Q6YHK3 2 +Abnormal muscle fiber protein expression 0.585527840692853 1.1918778443183973 0.2333091467190784 1.0 0.796900960662603 9 Q14118,Q9H9S5 2 +Abnormality of the pubic bone 0.562582519325319 1.1908411548648103 0.2337159491479017 1.0 0.796900960662603 11 Q8IZA0,Q7RTS9,Q5SZK8,Q04656 4 +Anterior uveitis 0.8463463373665341 1.1903468774239492 0.2339100831351677 1.0 0.796900960662603 3 P01889 1 +Epispadias 0.6096827728893652 1.1890438716856486 0.2344224034865387 1.0 0.796900960662603 7 P53701 1 +Hirsutism 0.3962203534046923 1.1868694025930089 0.2352791379796304 1.0 0.7975739945521857 70 Q04721,P16278,P51688,P54802,P53634,P10644,P15586,P08236,Q06136 9 +Abnormality of the crus of the helix 0.7029561634920056 1.1859166379684496 0.2356552219157957 1.0 0.7975739945521857 4 Q7LGA3 1 +Micronodular cirrhosis 0.5842638030035652 1.1858332823437396 0.2356881450318555 1.0 0.7975739945521857 9 P11717 1 +Yellow white lesions of the retina 0.8450791282641295 1.1855828480636876 0.2357870790724527 1.0 0.7975739945521857 3 Q99519 1 +Swan neck like deformities of the fingers 0.8452860596293275 1.185538794807702 0.2358044853458629 1.0 0.7975739945521857 2 Q9UBC1 1 +Gaze evoked horizontal nystagmus 0.8452860596293272 1.1855387948077003 0.2358044853458636 1.0 0.7975739945521857 2 Q9NWX6 1 +Slowly progressive 0.4072851813038848 1.1837866517394822 0.236497527442677 1.0 0.7987720930460044 65 O14773,Q8IV08,P31483,O95831,O14979,O75787,O00584,Q04656,P50402,P41440,Q13049 11 +Abnormal patella morphology 0.4438023772314988 1.178663843304301 0.2385320584885828 1.0 0.7992143564081391 33 Q04721,Q8WVQ1,Q9NX62,P22694,Q9Y619 5 +Macrovesicular hepatic steatosis 0.5827453873473709 1.178570629317887 0.2385691926423141 1.0 0.7992143564081391 9 Q7LG56,P23786 2 +Abnormality of the sense of smell 0.4571874615459357 1.1781314151786548 0.2387442196282687 1.0 0.7992143564081391 29 Q04656,O00592,P04062,O60266,Q9NQ11,Q15043 6 +Abnormal lung lobation 0.5080977744723055 1.177395534106023 0.2390376715379183 1.0 0.7992143564081391 16 P21964,Q5SZK8,Q9UBM7 3 +Visceral angiomatosis 0.8431372549019742 1.1768710869361834 0.2392469638577772 1.0 0.7992143564081391 2 P48735 1 +Hemangiomatosis 0.8431372549019742 1.1768710869361834 0.2392469638577772 1.0 0.7992143564081391 2 P48735 1 +Lymphangioma 0.8431372549019742 1.1768710869361834 0.2392469638577772 1.0 0.7992143564081391 2 P48735 1 +Color vision defect 0.4990809577206176 1.1761379419716516 0.2395397582620542 1.0 0.7992143564081391 18 Q8WWQ0,O00592,Q8WWV3,Q6P4Q7,Q9H6K4 5 +Abnormal sacroiliac joint morphology 0.8428686543110557 1.175788120639632 0.2396795546046837 1.0 0.7992143564081391 2 P01889 1 +Enthesitis 0.8428686543110557 1.175788120639632 0.2396795546046837 1.0 0.7992143564081391 2 P01889 1 +Sclerotic vertebral endplates 0.842868654311054 1.175788120639624 0.2396795546046868 1.0 0.7992143564081391 2 P51798 1 +Enlargement of the wrists 0.8428686543110524 1.1757881206396186 0.239679554604689 1.0 0.7992143564081391 2 O95831 1 +Short nail 0.6350659376394302 1.1733346078496347 0.2406616491792741 1.0 0.8007330580037715 6 Q04721,O75844 2 +Aplasia hypoplasia of the earlobes 0.5813021412347565 1.1716658956171715 0.2413312205485698 1.0 0.8018863318439089 9 P10586,P21964 2 +Abnormal muscle fiber alpha dystroglycan 0.8410473659726 1.1704359755104825 0.2418255652333085 1.0 0.8023396335900043 3 Q14118 1 +Fatigue 0.4218301984637884 1.1700057494115044 0.2419986551309034 1.0 0.8023396335900043 100 P01889,Q13501,P04062,P07602,P06280,Q8IWT6,Q07021,O15460,P10644,P17612,Q9NQ11,Q9UBC1,Q4J6C6,P02792,O00429,Q04656,Q13423,Q7LG56,Q68CQ7,P35637,Q92804,O00592,Q02241 23 +Craniofacial osteosclerosis 0.8409199805691068 1.1699576696368434 0.2420180041485495 1.0 0.8023396335900043 3 P51798 1 +Onychogryposis 0.8408337598477063 1.1696339381465204 0.2421483135946078 1.0 0.8023396335900043 3 P53634 1 +Microcornea 0.4424881834848493 1.168306581838999 0.2426831214022069 1.0 0.8035469925641895 33 O43505,Q9P273,O75845,Q8NCH0,Q14118,Q9H9S5 6 +Intracranial hemorrhage 0.4613189218156511 1.167075767360729 0.2431797729838898 1.0 0.8041948614027293 27 P17301,P23786,O75844,P04062,Q6YHK3,P05067 6 +Abnormality of circulating adrenocorticotropin level 0.5578151600389707 1.1666041799713798 0.2433702545295686 1.0 0.8041948614027293 11 Q13423 1 +Frequent falls 0.4321785567770586 1.1656938197432127 0.2437382598115067 1.0 0.8045162167141684 45 P15289,Q13510,P04062,P07602,Q9H9S5 5 +Myelomeningocele 0.6531694592631152 1.1651152004911365 0.2439723647527762 1.0 0.8045162167141684 5 Q5SZK8,Q8TAA9 2 +Heart block 0.4610379416387327 1.1650478707724434 0.2439996160978284 1.0 0.8045162167141684 27 Q07954,P06280,P23786,P50402 4 +Poikilocytosis 0.5266075158639107 1.1633504282936775 0.2446873533287215 1.0 0.8049640755048604 14 O75845,O14936,P11166,P41440 4 +Coxa vara 0.5012187961173253 1.1615144067882914 0.2454327678129202 1.0 0.8049640755048604 17 O75718,Q8WVQ1,O95831,Q7RTS9,Q04656,Q9Y487 6 +Absent septum pellucidum 0.4334516295250213 1.1613495066546642 0.2454997942143271 1.0 0.8049640755048604 41 Q9H9B1,O43505,Q15392,Q08J23,Q14118,Q9Y6N7,P53701 7 +Limb girdle muscular dystrophy 0.568090510643595 1.1611394254184946 0.2455852038212631 1.0 0.8049640755048604 10 O14979,Q14118 2 +Abnormal cochlea morphology 0.6967220150718777 1.1606283703130085 0.245793062903715 1.0 0.8049640755048604 4 O43405 1 +Photophobia 0.4326140806760378 1.1605064065264743 0.2458426868986212 1.0 0.8049640755048604 43 P04439,P01889,Q9Y287,Q8WWV3,Q9HCM3,P07602,Q6P4Q7 7 +Tetraparesis 0.4335199227821502 1.157336919686904 0.2471347351809429 1.0 0.806638950422115 38 Q13501,P07602 2 +Diabetes insipidus 0.4999362159400006 1.1537482916167696 0.2486033790645192 1.0 0.8067205315135637 17 Q9Y6N7,P06280,O15460,P01889 4 +Abnormality of the lymph nodes 0.4256873026637989 1.1513076525881596 0.2496056899982113 1.0 0.8094159754756303 51 P14174,P01889,P15260,Q13510,P13051,P10644,P51798 7 +Ambiguous genitalia male 0.8351711840963273 1.1483901567949033 0.2508075353311527 1.0 0.8105645865771031 3 Q15392 1 +Slender long bone 0.4847276389046484 1.1483082476416018 0.2508413355220007 1.0 0.8105645865771031 20 Q9Y619,Q9Y487,Q32P28 3 +Abnormal circulating bilirubin concentration 0.4500622488696307 1.1477897794001433 0.2510553575955618 1.0 0.8105645865771031 30 O75845,P23786,O14936,P11166,P41440,Q86WC4 6 +Adducted thumb 0.4584024324313406 1.1460123702422649 0.2517900336830994 1.0 0.8105645865771031 27 P42892,Q86XL3,Q8NCH0,Q92581 4 +Abdominal pain 0.4140115175188072 1.145865213613521 0.2518509266883257 1.0 0.8105645865771031 96 P42892,P14174,P01889,P23786,O15460,Q13423,P07686,P04062,P10644,Q04656,P06280,O14936,Q14108 13 +Coronary artery atherosclerosis 0.6479441512432518 1.1431233019384224 0.2529874007716919 1.0 0.8119243130742901 5 P01130 1 +Abnormality of circulating glucocorticoid level 0.5127713306909036 1.1423547076379013 0.2533066096568994 1.0 0.8119243130742901 15 P17252,O00255,Q13423,P10644,P17612,Q92560,O43716 7 +Large for gestational age 0.5748541314611652 1.140800110102321 0.2539531148037097 1.0 0.8134435708556328 9 Q8NCE2,P31751,P42345,Q9H9B1 4 +Distal upper limb amyotrophy 0.5214605278740879 1.1346439131027966 0.2565245460295375 1.0 0.8168696028489418 14 Q13501 1 +Increased muscle lipid content 0.5626938084559838 1.1345069803953236 0.2565819473635806 1.0 0.8168696028489418 10 P23786 1 +Large earlobe 0.5852392387823062 1.1327340640178694 0.2573259481419554 1.0 0.8172184831148294 8 Q15392 1 +Pathologic fracture 0.491950542016664 1.1321192610229494 0.2575842981954601 1.0 0.8172184831148294 18 Q04721,P04062,P22626,O15269,Q14108 5 +Abnormality of alkaline phosphatase level 0.4534961636125099 1.1297015903585252 0.2586019868806153 1.0 0.8177789189417178 28 Q13501,Q8N511,P22626,P38571,P51798 5 +Multiple prenatal fractures 0.5961471065621199 1.1276992655496916 0.2594469479495087 1.0 0.819118373465609 7 Q32P28 1 +Vascular skin abnormality 0.4757893972204309 1.1274615027046562 0.2595474083489177 1.0 0.819118373465609 144 P07858,P01889,Q16625,P22830,P04062,P00533,P06280,Q9Y487,P17301,P16278,O00462,Q8IZA0,P10644,Q06136,P10619,P51798,Q14108,Q08J23,P21964,Q8NCH0,O75844,P04066,Q99519,P53701,Q6YHK3,Q07954 26 +Thick eyebrow 0.4183995293694685 1.1270520854966786 0.2597204598793394 1.0 0.819118373465609 55 Q04721,O00754,Q96EK5,Q08J23,O95831,P08236,O94766,P15586,Q92581,P04066 10 +Abnormal temper tantrums 0.5718120034999564 1.1262292364992204 0.2600685013952002 1.0 0.8196677701058617 9 P04062,Q9BVA1,Q06787,Q93009 4 +Microretrognathia 0.4757148202403028 1.1244143517486491 0.2608372864056401 1.0 0.8200031944093737 21 Q8WVQ1,Q16625,Q8NCH0 3 +Abnormality of the gallbladder 0.4275290215158562 1.1169318287344323 0.2640234743270002 1.0 0.8233271702723585 43 P15289,O75845,P21964,O00192,P22830,P04062,P07602,P04066,Q9UBM7 9 +Eyelid myoclonus 0.5691813423215567 1.113625480455289 0.265439890502263 1.0 0.8255600816082916 9 Q01105,P67870,Q13510 3 +Increased blood pressure 0.402114478012962 1.1084809071433468 0.2676541803452483 1.0 0.8287429597094094 90 P42892,P01130,Q04721,P01889,P21964,O75844,P04062,P10644,P00533,Q96J02,P06280,P38571,Q8TAA9,O94898,Q06787,Q13049 16 +Cholecystitis 0.5679050306005691 1.1075094664877527 0.2680737217288711 1.0 0.8287429597094094 9 P07602 1 +Abnormality of the inner ear 0.5259024261614151 1.107091639238715 0.268254309957407 1.0 0.8287429597094094 13 P10644,O43405 2 +Weakness of muscles of respiration 0.4271586432038385 1.1050461283996085 0.2691396017809586 1.0 0.829949785740497 39 Q8NCE2,O95831,Q7RTS9,Q13510,P10253,P06753,P22626,O95140,P43243,P50402,P50336,Q7LG56,Q969X5,Q9BTV4,P09651 15 +Iris coloboma 0.4260483850679038 1.104216238580611 0.2694993471855129 1.0 0.8302719808785406 43 Q04721,Q96EK5,O43505,Q9P273,Q9UBM7,Q14118,Q9H9S5,P98164,P53701 9 +Abnormality of the vertebral endplates 0.56706149938127 1.1034669634054917 0.269824430602966 1.0 0.8304322390946376 9 P22413,Q7RTS9,P51798,O15228 4 +Abnormal electroretinogram 0.4263922102070581 1.0981612060398989 0.2721341027749593 1.0 0.8343503208447037 37 O14773,P50897 2 +Hepatitis 0.4662011704899211 1.09810364227341 0.2721592350920794 1.0 0.8343503208447037 22 Q8IWT6,Q04656,Q96J02,Q9Y619,P08236,P11717 6 +Erythrocyte inclusion bodies 0.637070383437151 1.0973990119897188 0.2724670051406086 1.0 0.8347510911227873 5 Q9Y606,O14936 2 +Abnormality of the tonsils 0.565194180553649 1.094517208573373 0.2737282042110065 1.0 0.8369834519162749 9 P21964,P31751 2 +Deviation of the 2nd finger 0.6163185009272825 1.092076005615645 0.2747996949507698 1.0 0.8380649491047829 6 Q9H6K4 1 +Delayed puberty 0.405594977193897 1.090644245203032 0.2754294527034624 1.0 0.8386047031033396 61 Q04721,O75844,P04062,P51809,P06280,P16870,Q14108,Q9Y6N7 8 +Abnormal sharpey fiber morphology 0.5641237638399632 1.0893863744103025 0.275983537476772 1.0 0.8386047031033396 9 P29992,Q04656,P01889 3 +Cerebral hemorrhage 0.5132986867563613 1.0890462200987805 0.2761335039787811 1.0 0.8386047031033396 14 P05067 1 +Abnormality of fontanelles 0.4129609995745292 1.0882478067607724 0.2764857250152819 1.0 0.8386047031033396 56 Q9Y5Y5,O75718,Q32P28,Q08J23,Q8NCH0,O75844,Q9Y619,Q9Y487,P98164 9 +Spastic tetraplegia 0.4241963673421668 1.085293090941941 0.2777918649668871 1.0 0.8386047031033396 42 Q86XL3,P16278,P15289,P04066,Q86WC4 5 +Aspiration pneumonia 0.4499892549784928 1.085079361472328 0.2778865073243854 1.0 0.8386047031033396 27 P16278,Q13510 2 +Hypergranulosis 0.8200376040827271 1.0841944177773937 0.2782786062163467 1.0 0.8386047031033396 2 P22413 1 +Male reproductive system neoplasm 0.4837717082356839 1.0814958006860709 0.2794766276465132 1.0 0.8386047031033396 18 Q01844,Q13423,P10644,Q14145,P51809 5 +Abnormality of the pulmonary veins 0.5858236941710202 1.080895662182152 0.2797435284357608 1.0 0.8386047031033396 7 Q15392 1 +Anomalous trichromacy 0.8169860260859726 1.0804318816017011 0.2799499051293015 1.0 0.8386047031033396 3 Q9H6K4 1 +Tritanomaly 0.8169860260859726 1.0804318816017011 0.2799499051293015 1.0 0.8386047031033396 3 Q9H6K4 1 +Atelectasis 0.5208096978812786 1.0794749117710445 0.2803760719426429 1.0 0.8390071941791317 13 P21964,Q13510 2 +Ambiguous genitalia 0.4514031883840036 1.0780914985982633 0.2809929251590046 1.0 0.8390071941791317 26 Q15392,O75845,Q5SZK8,P51809,Q8TAA9,P53701 6 +Abnormal cerebral vascular morphology 0.379090056102451 1.0779228286268925 0.2810681967584818 1.0 0.8390071941791317 76 P17301,P01130,P51970,P23786,P10253,O75844,P04062,P10644,P06280,Q6YHK3,P05067 11 +Abnormal heart valve morphology 0.4059709131048937 1.0729054811377403 0.2833135265586382 1.0 0.8399467551891883 95 P01889,Q5H8A4,P04062,P06280,P16278,P34059,Q15477,P10644,P08236,P55795,P51798,Q9NZJ4,P22413,P21964,Q8NCH0,O75844,O94766,O00571,P53701,O00192,Q06787 21 +Attenuation of retinal blood vessels 0.5494025924814769 1.0688372261588868 0.2851430219308257 1.0 0.8405527340984226 10 P04439 1 +Limb myoclonus 0.629037346109097 1.063670091688855 0.2874781777965491 1.0 0.8414032907267839 5 Q13510 1 +Pharyngitis 0.8123766217237802 1.0632809084636687 0.2876545803867563 1.0 0.8414032907267839 3 P01889 1 +Abnormal z disc morphology 0.8122482027856978 1.062803559790347 0.2878710448621429 1.0 0.8414032907267839 3 Q13501 1 +Abnormal sarcomere morphology 0.8122482027856978 1.062803559790347 0.2878710448621429 1.0 0.8414032907267839 3 Q13501 1 +Chronic infection 0.5480344131017478 1.0620728513419813 0.2882026137918108 1.0 0.8414032907267839 10 P10644 1 +Abnormal circulating ferritin concentration 0.56966273722985 1.060134502833537 0.2890834130696433 1.0 0.8414032907267839 8 P02792,P41440 2 +Recurrent fractures 0.4217678522868504 1.0598051870121217 0.289233236556317 1.0 0.8414032907267839 37 Q04721,O75718,Q32P28,Q13501,Q04656,P48735,P51798 7 +Reduced visual acuity 0.4680485173951864 1.058880330890589 0.2896542830619906 1.0 0.8414032907267839 143 O43505,Q9P273,P01889,P07602,Q9H6K4,P17900,Q9ULH0,P17301,P16278,P50897,P15289,P06865,Q07021,Q5SZK8,Q86YV9,Q9Y2Y6,P07686,P51798,O43676,O00459,O96000,O94766,Q15043,P53701,Q8WWV3,Q9HCM3,Q6YHK3,Q9H9S5,Q8NHS3 29 +Periodontitis 0.5365468579516799 1.0582271457965955 0.2899518982039426 1.0 0.8414032907267839 11 P53634 1 +Phalangeal dislocation 0.8133225893097145 1.0574531832456275 0.2903048103797196 1.0 0.8414032907267839 2 Q8WVQ1 1 +Atlantoaxial dislocation 0.8133225893097142 1.0574531832456262 0.2903048103797203 1.0 0.8414032907267839 2 Q8NCH0 1 +Large iliac wing 0.8133225893097091 1.0574531832456062 0.2903048103797294 1.0 0.8414032907267839 2 Q04656 1 +Visual hallucinations 0.5804620478273051 1.0565920468719026 0.2906978117617251 1.0 0.8414032907267839 7 P04062,Q9NQ11 2 +Irritability 0.3930883211569616 1.055808000872442 0.291055942136879 1.0 0.8414032907267839 87 Q9H9B1,P50897,Q9NUM4,P01889,Q13501,Q13510,Q5KU26,P07602 8 +Fever 0.402910152989185 1.0546141766450643 0.2916018174050305 1.0 0.8424648094759308 94 P14174,P01889,P15260,Q13510,P23786,P10253,O15460,P10644,P07602,P06280,P38571,Q9NQ11 12 +Metamorphopsia 0.6701378576221217 1.0531706955825122 0.2922627665520017 1.0 0.8434821048718747 4 P22413,P29992 2 +Abnormal muscle glycogen content 0.60646304883379 1.0494038045302947 0.2939923079320907 1.0 0.8447128165142034 6 Q9BUK6 1 +Cardiac conduction abnormality 0.4271999230894369 1.0472251602696383 0.2949957436451518 1.0 0.8454737615899833 33 Q07954,O75306,P23786,P04899,P06280,P50402,Q7LG56,P0DP25 8 +Osteolysis involving bones of the feet 0.624024479268414 1.0426505789660263 0.2971101547324544 1.0 0.8469615354072082 5 O75844 1 +Foot acroosteolysis 0.624024479268414 1.0426505789660263 0.2971101547324544 1.0 0.8469615354072082 5 O75844 1 +Decreased circulating igg level 0.4814042286658164 1.0411868359393417 0.2977888440808236 1.0 0.8470919642536731 17 P13051 1 +Abnormality of the chin 0.4070461246683025 1.0385228289766697 0.2990267126457886 1.0 0.8478487895492836 98 Q9H9B1,O00754,Q04721,P16278,P34059,P11233,Q96EK5,Q08J23,Q9BUK6,P22694,O75844,P10644,Q96J02,Q06787,Q7LGA3,Q07954,Q92581,Q05086 18 +Difficulty walking 0.4042293695436724 1.0382032318153185 0.2991754483729869 1.0 0.8478487895492836 96 O14773,P02792,P31483,P15289,Q13501,Q9BUK6,Q13510,Q14118,Q9H2C2,P07602,Q9NQ11,Q9H9S5 12 +Megalencephaly 0.80768197690035 1.0350714067935016 0.300635564717628 1.0 0.8487202817040475 2 O00459 1 +Venous thrombosis 0.5035034151408146 1.0342223313068502 0.3010322366897486 1.0 0.8487202817040475 14 P10644,P01889 2 +Abnormal gallbladder morphology 0.4183454756609199 1.0340813305225935 0.3010981433231599 1.0 0.8487202817040475 35 P15289,O75845,P21964,P22830,P04062,P07602 6 +Recurrent bacterial skin infections 0.8043474859455095 1.033488792724355 0.3013752125903575 1.0 0.8487202817040475 3 P53634 1 +Abnormal posterior segment imaging 0.5638841957336399 1.0332020033326468 0.3015093755813318 1.0 0.8487202817040475 8 P04439 1 +Obsessive compulsive trait 0.6215243659535831 1.032176828708325 0.3019892877847079 1.0 0.8487202817040475 5 Q06787,O75503 2 +Osteolysis involving bones of the upper limbs 0.5520853671708285 1.0316689619495878 0.3022272222653437 1.0 0.8487202817040475 9 O75844,P53634 2 +Dermatological manifestations of systemic disorders 0.3863113161090151 1.0281466296228812 0.3038808591053987 1.0 0.8498615446311616 84 Q9Y5Y5,P61916,Q16625,Q15904,O75787,Q04656,P04066,O75844,P10644,P38571,P11166,O15118 12 +Abnormal urine protein level 0.3957812789207018 1.0274258436590653 0.3042199874412259 1.0 0.8498615446311616 63 Q04721,O95470,Q96J84,P04062,P06280,Q14108,P98164,Q99519 8 +Temperature instability 0.5409430123075173 1.0270059267606877 0.304417673308329 1.0 0.8498615446311616 10 Q9H270,P07602 2 +Increased hepatic glycogen content 0.6197536207643723 1.024762792192276 0.30547512668997 1.0 0.8502451135438067 5 Q93100 1 +Septo optic dysplasia 0.6620757969648856 1.0207508919248476 0.3073724761865666 1.0 0.8519218578586426 4 Q9Y6N7 1 +Gliosis 0.4157967816683935 1.01906165333139 0.3081736976717142 1.0 0.85272240875712 44 Q9H9B1,P35637,O00754,Q13501,Q9H9P8,P04062,Q7KZN9,Q6PJG6 8 +Sensory axonal neuropathy 0.468694463047945 1.0149005377416018 0.3101532418528772 1.0 0.8560661219843062 19 O95831,Q8IV08,Q9NQ11 3 +Abnormality of lower lip 0.3747386722225893 1.012098153444526 0.3114911252141796 1.0 0.8568731945069178 77 Q9H9B1,P04062,Q9Y619,Q7LGA3,P06280,P15586,P11166,P04066,Q99519 9 +Skin vesicle 0.5156081407927836 1.00607719809409 0.31437843630049 1.0 0.8609063956657035 12 Q14574,Q9NPE3,P98194,P16615 4 +Abnormality of the axillary hair 0.5692398068502535 1.005757275538249 0.3145323439674259 1.0 0.8609063956657035 7 Q14574,P51809 2 +Abnormal 2nd finger morphology 0.5579044519327148 1.0053415234837202 0.314732427093348 1.0 0.8609063956657035 8 Q9H6K4 1 +Abnormal synaptic transmission at the neuromuscular junction 0.4219227499923284 1.0051975913142568 0.3148017147897304 1.0 0.8609063956657035 33 P35637,Q92804,Q13501,Q9UNW1,Q7LG56,Q68CQ7,P29992,Q9H9S5 8 +Abnormal blood phosphate concentration 0.5255540711238591 1.00211589695309 0.3162876209323648 1.0 0.8625010687529472 11 P10644,P29992,P51798 3 +Atrioventricular canal defect 0.514802429933609 1.00182737012685 0.316426975723731 1.0 0.8625010687529472 12 P17252,Q12768,P19022,P22694,P17612,Q9UBM7 6 +Hyperlordosis 0.4011844116890876 1.0016922977311744 0.3164922278194433 1.0 0.8625010687529472 58 P16278,P34059,Q8WVQ1,P22626,Q14118,Q96J02,P50402,P04066,Q9H9S5 9 +Abnormality of the metaphysis 0.3811587520966119 0.9998175204614446 0.3173988253325528 1.0 0.8635861656563824 69 Q04721,P16278,P34059,Q8WVQ1,O95831,Q04656,P48735,P51798,Q86WC4 9 +Peripheral demyelination 0.4743704970917208 0.9983258469709144 0.318121378098136 1.0 0.863730105703038 17 P07602 1 +Limited wrist movement 0.567565953744272 0.9981809894270348 0.3181916031075729 1.0 0.863730105703038 7 Q9H6K4 1 +Abnormality of the spinocerebellar tracts 0.792983928974131 0.991525514560416 0.3214290400062127 1.0 0.8680056836364795 3 O00754 1 +Abnormal epidermal morphology 0.4553109346153554 0.9898167340221296 0.3222637040210485 1.0 0.8691990207253795 21 P01889,Q14574,O75844,P00533,Q07954 5 +Fair hair 0.6539283936185571 0.9880932981641678 0.3231069576705405 1.0 0.8695486903062777 4 P10644 1 +X linked recessive inheritance 0.3967938615788634 0.9875599569551332 0.3233682054517857 1.0 0.8697553272704903 60 P38159,O95831,Q15904,O75787,Q04656,Q9UPP1,P06280,P50402,Q92581 9 +Abnormal thyroid hormone level 0.7912333587689424 0.9850839404721076 0.3245828411064004 1.0 0.8706549133991015 3 P16870 1 +Abnormality of the parathyroid morphology 0.5907196364668472 0.9813823658929286 0.3264042188244864 1.0 0.8708053911702384 6 P10644 1 +Parathyroid adenoma 0.5907196364668472 0.9813823658929286 0.3264042188244864 1.0 0.8708053911702384 6 P10644 1 +Neoplasm of the parathyroid gland 0.5907196364668472 0.9813823658929286 0.3264042188244864 1.0 0.8708053911702384 6 P10644 1 +Abnormal larynx morphology 0.4154247947783674 0.9805238507310792 0.32682760236648 1.0 0.8708053911702384 34 P07602,Q13510,Q5SZK8 3 +Abnormal corpus striatum morphology 0.4632722568335659 0.9805039288312544 0.3268374312418891 1.0 0.8708053911702384 19 O95831,P02792,Q9NQ11,O75306 4 +Limb girdle muscle weakness 0.4251169443896267 0.9804784236131584 0.3268500150414366 1.0 0.8708053911702384 31 O14979,P07602,Q9H9S5,Q14118 4 +Protruding tongue 0.4746042907460644 0.9776029629354424 0.3282707313550959 1.0 0.8719980272333955 16 Q9H9B1,P67870,Q05086,Q99519 4 +Hiatus hernia 0.5405510786075274 0.9763798803003548 0.3288762481055785 1.0 0.8724089328409605 9 Q8NCH0 1 +Stillbirth 0.4931650410471727 0.9762767346653904 0.3289273459384423 1.0 0.8724089328409605 14 P04062,Q86WC4 2 +Abnormality of the foot musculature 0.6507572805006825 0.9754144979543132 0.3293546949993902 1.0 0.8724089328409605 4 Q8NCE2,O14979 2 +Spastic tetraparesis 0.4387651251447839 0.9729320965549888 0.33058705154306 1.0 0.8724089328409605 25 P07602 1 +Cutaneous cyst 0.6499241892842401 0.9720868124759467 0.3310073621949598 1.0 0.8724089328409605 4 Q8TAA9 1 +Tetany 0.5878394086630152 0.9689648352578843 0.3325627345307596 1.0 0.8749182145689296 6 P21964 1 +Abnormality of secondary sexual hair 0.5389127030680866 0.9685303677582728 0.3327795602365222 1.0 0.8749182145689296 9 Q14574,P51809 2 +Abnormal sensory nerve conduction velocity 0.5494897031995175 0.9661662421508546 0.3339610019601879 1.0 0.8770409267192044 8 Q9NZJ4,O15269,O95140,Q7LG56 4 +Generalized amyotrophy 0.430751202210586 0.9619460921159464 0.3360766837694324 1.0 0.8778956033090715 28 Q13501 1 +Abnormal lymphocyte morphology 0.4083223075391587 0.9573446043647592 0.3383933487793458 1.0 0.879561543271563 45 P16278,P04066,Q99519 3 +Generalized joint laxity 0.4978823866989071 0.9549179500928008 0.3396191915487456 1.0 0.8798480690627093 13 Q9BUK6,Q9Y487,Q8NCH0 3 +Pelvic girdle muscle weakness 0.5158800409985269 0.9527303296456424 0.3407267220727759 1.0 0.8798480690627093 11 O14979,Q9H9S5 2 +Aplasia hypoplasia of the sacrum 0.7822781277206441 0.952236058802454 0.3409772774997162 1.0 0.8798480690627093 3 P04066 1 +Facial capillary hemangioma 0.7815690488984383 0.9496429762555448 0.34229369361258 1.0 0.8798480690627093 3 Q10469,Q9UBM7 2 +Inguinal hernia 0.3933235467456007 0.9481497117552694 0.3430532438341618 1.0 0.8798480690627093 94 Q9H9B1,O00754,Q04721,P16278,P34059,Q32P28,P21964,P51970,Q8NCH0,Q04656,Q9Y487,P08236,O94766,Q99519 14 +Schistocytosis 0.643280166613677 0.945598452722819 0.3443534337345673 1.0 0.8798480690627093 4 P41440 1 +Shield chest 0.5820730148061709 0.9441357159456976 0.3451003000440067 1.0 0.8809105679170817 6 P04066 1 +Esophageal stricture 0.5993180945488845 0.9395074651561192 0.3474702612584444 1.0 0.8824690679792367 5 P01889 1 +Impaired temperature sensation 0.5542122453242929 0.9378234014677648 0.3483351728100561 1.0 0.8824690679792367 7 P07686 1 +Femoral hernia 0.6408594170264231 0.9359708818532996 0.3492881799999132 1.0 0.8824690679792367 4 Q9H9B1 1 +Acquired abnormal hair pattern 0.5537552856475035 0.9357612258780522 0.3493961392655567 1.0 0.8824690679792367 7 O75844 1 +Cerebral white matter atrophy 0.4421507796957439 0.9356688023736556 0.3494437381191306 1.0 0.8824690679792367 22 Q2TAA5,O00754,Q9Y5Y5,Q9H9P8,P51970,O00429,O75503 7 +Osteomyelitis 0.4558417532282623 0.9333122409654038 0.350658776756537 1.0 0.8824690679792367 19 O15269,P15260,P51798 3 +Lambdoidal craniosynostosis 0.7813591189900579 0.931764720685889 0.3514581306229962 1.0 0.8824690679792367 2 P61978 1 +Multiple rib fractures 0.781090518399159 0.930721505870864 0.3519976421582838 1.0 0.8824690679792367 2 O75718 1 +Abnormal circulating androgen level 0.4667201537289309 0.93038855115564 0.3521699441678425 1.0 0.8824690679792367 16 Q13423,P16870,P51809 3 +Abnormal circulating proline concentration 0.6391722700274706 0.9292687535158192 0.3527498242041305 1.0 0.8824690679792367 4 O96000 1 +Dysuria 0.5411297563752111 0.927299940855668 0.3537708250430729 1.0 0.8824690679792367 8 P01889 1 +Recurrent upper and lower respiratory tract infections 0.7754200592719983 0.9272074494026656 0.3538188358043961 1.0 0.8824690679792367 3 P13051 1 +Vitreous hemorrhage 0.6378027121801433 0.9238330972134922 0.3555732202517006 1.0 0.8828476742952965 4 P29992,Q92560 2 +Abnormal paranasal sinus morphology 0.4228043626935573 0.920985724592815 0.3570578801449435 1.0 0.8829566558384138 29 Q04721,Q8IWT6,O00754,P10644,Q06787,Q15833,P04066 7 +Upper limb asymmetry 0.7784045124899237 0.9203028312792494 0.3574145299441873 1.0 0.8829566558384138 2 P07437 1 +Cerebellar malformation 0.3691783996043351 0.917661809312791 0.3587959476576454 1.0 0.8829566558384138 71 Q04721,O00754,O43505,P14543,P23786,Q14118,Q9Y487,Q15043,Q9H9S5 9 +Abnormality of the glenoid fossa 0.7718139259175515 0.9140943132871122 0.3606672903801651 1.0 0.8829566558384138 3 Q9Y619 1 +Conspicuously happy disposition 0.7716791833971696 0.9136050029123168 0.3609244366453707 1.0 0.8829566558384138 3 Q92581 1 +Progressive inability to walk 0.4283130206348855 0.912018586133628 0.3617589336031113 1.0 0.8829566558384138 26 Q92581,Q15043,Q99519 3 +Aortic valve calcification 0.7709871886150155 0.911092821035136 0.3622464686944497 1.0 0.8829566558384138 3 P04062 1 +Female sexual dysfunction 0.507604617710378 0.9105088783949664 0.3625542016286667 1.0 0.8829566558384138 11 O00592 1 +Abnormal cardiac test 0.4332195524386987 0.9103562882254856 0.3626346423554056 1.0 0.8829566558384138 23 P10253 1 +Abnormality of skeletal muscle fiber size 0.4314622823083633 0.908827440439901 0.3634412195431711 1.0 0.8829566558384138 24 O95831,Q13501,Q9BUK6,Q13049 4 +Anosmia 0.5474534836830528 0.907349571086589 0.3642219679593768 1.0 0.8829566558384138 7 Q9NQ11,O60266 2 +Turricephaly 0.5258134114620265 0.9058383540441496 0.365021417100962 1.0 0.8829566558384138 9 P21964,O00192 2 +Oromandibular dystonia 0.5909040668138508 0.9046101633462852 0.365671949136833 1.0 0.8829566558384138 5 Q15043 1 +Cranial hyperostosis 0.4799092055880309 0.9019319416548098 0.3670930222809896 1.0 0.8829566558384138 14 O00754,P10644,Q15043 3 +Fibrous tissue neoplasm 0.4317981570654989 0.9004970696147353 0.3678557840797567 1.0 0.8829566558384138 23 Q07954,Q15392 2 +Telangiectasia of the skin 0.4263210641099675 0.8976383661697167 0.3693783779629653 1.0 0.8829566558384138 26 P06280 1 +Aplasia hypoplasia involving the nose 0.4083300137397833 0.8964875169647607 0.369992444361938 1.0 0.8829566558384138 33 Q5KU26,P10644,Q5SZK8,Q08J23 4 +Paraplegia paraparesis 0.3899775770211774 0.8952912604450699 0.3706314109275666 1.0 0.8829566558384138 95 P35637,O00754,Q9Y5Y5,Q04446,O95831,Q13501,Q6DKK2,O75787,Q13510,Q8WWQ0,P04062,Q9Y619,Q7KZN9,P11166,Q9H6K4,Q9NQ11,Q9ULH0 17 +Neoplasm of the adrenal cortex 0.534061193393019 0.8944958830107864 0.3710566315525518 1.0 0.8829566558384138 8 P10644 1 +Triceps weakness 0.7716894977169081 0.8943669858336468 0.371125570401317 1.0 0.8829566558384138 2 Q6PIJ6 1 +Abnormal size of the clitoris 0.4408902122014491 0.8942626788894288 0.37118136332673 1.0 0.8829566558384138 21 Q9Y5Y5,Q9Y619,P51809,P53701 4 +Accessory oral frenulum 0.5702399339730162 0.8933412360503559 0.37167446156257 1.0 0.8829566558384138 6 P17252,P17612,P22694 3 +Hamartoma of tongue 0.6300264558076693 0.8930569300162589 0.3718266862427526 1.0 0.8829566558384138 4 P08754 1 +Prominent calcaneus 0.7711522965350559 0.8922991945565462 0.3722325858710276 1.0 0.8829566558384138 2 Q7RTS9 1 +Hypoplastic ischia 0.7711522965350532 0.8922991945565375 0.3722325858710322 1.0 0.8829566558384138 2 Q15643 1 +Severe demyelination of the white matter 0.629762743699446 0.8920159510928094 0.3723843826890336 1.0 0.8829566558384138 4 Q9H9P8 1 +Abnormal shape of the occiput 0.4075903890016739 0.8905560092837788 0.3731674080907048 1.0 0.8829566558384138 33 Q9H9B1,Q04721,Q9Y5Y5,O00754,P14543,Q04656,Q96J02 7 +Redundant neck skin 0.5220407582030216 0.8878128884396957 0.3746414089195804 1.0 0.8829566558384138 9 O96000 1 +Fluctuations in consciousness 0.5416586482096255 0.8812742298785601 0.3781694106801696 1.0 0.8829566558384138 7 O00255,P04062,O75306 3 +Abnormal delivery 0.4196333470352409 0.8794404531893129 0.3791625063218036 1.0 0.8829566558384138 28 Q8NCE2,P17301,O75718,P22413,P50570,Q02809,O75844,P06753,Q9Y619,Q6YHK3,Q9Y487,Q969X5,Q9H3S7,Q9UBM7 14 +Abnormal liver parenchyma morphology 0.7673918882621755 0.8778551148061972 0.3800223501810684 1.0 0.8829566558384138 2 P23458 1 +Dyspareunia 0.5842990368620018 0.8773205384214386 0.3803125596813625 1.0 0.8829566558384138 5 P01889 1 +Upgaze palsy 0.5405896144474042 0.8764698054370593 0.3807746842027426 1.0 0.8829566558384138 7 P02792 1 +Abscess 0.4908764676860423 0.8756547964281854 0.3812177264936873 1.0 0.8829566558384138 12 P53634 1 +Cupped ear 0.4573359858739944 0.8741679289730743 0.3820268086672782 1.0 0.8829566558384138 16 Q15392 1 +Cutaneous photosensitivity 0.421014563432081 0.873661160537996 0.3823028082883448 1.0 0.8829566558384138 27 P22830,Q14108,Q06136,Q08J23 4 +Flat occiput 0.4571253438093919 0.8729060321346676 0.3827142981273854 1.0 0.8829566558384138 16 Q9H9B1,O00754,Q9Y5Y5 3 +Hypopigmentation of the skin 0.3898592000031283 0.86766195551643 0.3855794186910906 1.0 0.8829566558384138 56 Q9Y2Q5,Q15477,P53634,P21964,Q86YV9,Q04656,O00192,Q8IZA0,P07602,P51798,Q05086,P53701 12 +Coloboma 0.3885343450622912 0.8662668092712213 0.3863438632712137 1.0 0.8829566558384138 57 Q04721,Q96EK5,O43505,Q9P273,Q14118,O14936,Q9H9S5,P98164,P53701 9 +Bundle branch block 0.4734036182905693 0.8654584550956401 0.386787208999293 1.0 0.8829566558384138 14 P06280 1 +Ventricular arrhythmia 0.3987007012474183 0.8648281631564526 0.3871331109232538 1.0 0.8829566558384138 41 P42892,P23786,P10253,P13473,P04899,P50402 6 +Mediastinal lymphadenopathy 0.5633267640828222 0.8637832463740662 0.3877069729450912 1.0 0.8829566558384138 6 O15460,P01889 2 +Dyspnea 0.4101806802351789 0.8637434260983238 0.3877288522524384 1.0 0.8829566558384138 112 P01130,Q92804,P01889,O95831,Q13501,P51970,Q13510,P23786,P10253,O75844,P04062,P10644,Q9Y619,P07602,P06280,Q68CQ7,P53701 17 +Decreased calvarial ossification 0.6224746035758985 0.8633224555472138 0.3879602011515759 1.0 0.8829566558384138 4 O75844 1 +Abnormal glial cell morphology 0.3704650024667888 0.8620033080254454 0.3886856974680663 1.0 0.8829566558384138 68 Q9H9B1,P35637,O00754,Q9NUM4,O95831,Q13501,Q9H9P8,P04062,Q7KZN9,P48735,Q6PJG6 11 +Aplastic clavicle 0.5628639282742274 0.8618078663432795 0.3887932554490678 1.0 0.8829566558384138 6 Q9Y619 1 +Hepatic fibrosis 0.3982917396244059 0.8612845803957324 0.3890813260972956 1.0 0.8829566558384138 39 P04062,Q15904,Q13510 3 +Abnormality of hair texture 0.386766620908803 0.8612107461274975 0.3891219825613883 1.0 0.8829566558384138 58 Q04721,P51688,P54802,Q08J23,O75844,Q9Y487,P15586,P51798 8 +Upper limb amyotrophy 0.4518634293089588 0.8609199303028148 0.3892821439603073 1.0 0.8829566558384138 17 Q13501 1 +Abnormal number of permanent teeth 0.7625570776255658 0.8593648882122962 0.3901392349035861 1.0 0.8829566558384138 2 Q12959 1 +Abnormality of the nasolabial region 0.5620829149860289 0.8584755641356979 0.3906299179393215 1.0 0.8829566558384138 6 Q8NCH0 1 +Prominent nasolabial fold 0.5620829149860289 0.8584755641356979 0.3906299179393215 1.0 0.8829566558384138 6 Q8NCH0 1 +Protrusio acetabuli 0.7563138097796844 0.8581403866128368 0.3908149488075194 1.0 0.8829566558384138 3 O75718,Q96AY3 2 +Impaired smooth pursuit 0.4439442522354974 0.8576742337939388 0.3910723715604374 1.0 0.8829566558384138 19 O00754,P02792,P41440 3 +Fatty replacement of skeletal muscle 0.5156162545673828 0.8571590951502186 0.3913569654034829 1.0 0.8829566558384138 9 Q9H9S5,P51114 2 +Thick hair 0.515373169549613 0.8560004121548295 0.3919975514695613 1.0 0.883071407156704 9 Q9BUK6,Q9Y487 2 +Respiratory distress 0.3861244530757391 0.8549262926894189 0.3925919537701088 1.0 0.8831445906612896 58 O95831,Q13510,P23786,P10253,P04062,Q9Y619,P07602,P53701 8 +Contractures of the joints of the upper limbs 0.366250519751602 0.8498710807933277 0.3953967653544341 1.0 0.8857111760363908 81 P42892,Q15392,Q8WVQ1,P23786,Q8IZA0,O75844,Q9Y619,Q7LGA3,P50402,O94766 10 +Abnormality of the biliary system 0.4334910740477981 0.8498265497646359 0.3954215264417999 1.0 0.8857111760363908 131 P14174,Q16625,Q15904,P22830,P04062,P07602,P15289,P61916,Q13510,P10644,Q96J02,P38571,P11166,Q14108,Q9Y5Y5,P21964,O75787,Q04656,P04066,Q04721,O15118 21 +Proximal amyotrophy 0.4532717399220795 0.8498229154572324 0.3954235473078691 1.0 0.8857111760363908 16 O14979,Q9H9S5,P50402 3 +Amaurosis fugax 0.5049066692688312 0.8490571524491666 0.3958494910120951 1.0 0.886244230827174 10 P01889 1 +Abnormal protein glycosylation 0.4424952602896711 0.8484603314712371 0.3961816554499813 1.0 0.886566922376204 19 Q2TAA5,Q15904,O75787,Q8N511,Q9Y487,Q10469 6 +Adrenal hyperplasia 0.5767594333664456 0.8462978973231725 0.3973865805631467 1.0 0.8879989229171739 5 P10644,P17252,P17612 3 +Ureteral duplication 0.5040755892265464 0.8449675002780613 0.3981289848847105 1.0 0.888074699575389 10 O75844,P23786 2 +Autoimmunity 0.3962747000948614 0.8447639284485552 0.3982426581821725 1.0 0.888074699575389 42 P14174,P15260,P21964,Q8IZA0,Q96J02,Q06787,Q9UBC1 7 +Spastic paraparetic gait 0.5585121451072617 0.8432578123643479 0.399084271723658 1.0 0.888074699575389 6 Q15043 1 +Dysesthesia 0.5331321517931179 0.8430129278484707 0.399221213624731 1.0 0.888074699575389 7 Q8NCH0 1 +Hyperhomocystinemia 0.5755547645790309 0.8413549103737115 0.4001491374202823 1.0 0.888074699575389 5 P41440 1 +Obsessive compulsive behavior 0.3942677799280903 0.8406075963191078 0.4005678017281373 1.0 0.888074699575389 47 Q9H9B1,Q9NUM4,Q6DKK2,Q13501,Q06787,Q05086,O75503 7 +Nonketotic hypoglycemia 0.5578504116474708 0.8404409083091925 0.4006612204710511 1.0 0.888074699575389 6 P23786 1 +Delayed cranial suture closure 0.404208463036978 0.8397289345192616 0.4010603868829574 1.0 0.888074699575389 32 O75718,Q08J23,Q32P28,Q8NCH0,O75844,Q9Y487 6 +Macrocephaly at birth 0.756379264034383 0.8358771748985392 0.4032240043455797 1.0 0.8883638559079275 2 Q8NCE2 1 +Arterial stenosis 0.4404804569121449 0.8356490960725075 0.403352340103047 1.0 0.8883638559079275 19 P01130,Q04656,P01889 3 +Abnormal cranial nerve morphology 0.3549282511114374 0.8355809820247608 0.4033906713677355 1.0 0.8883638559079275 74 Q9Y5Y5,O43405,Q13501,Q13510,P10644,Q13049,P51798,Q15043,Q9H9S5 9 +Gastroparesis 0.4678391635206371 0.8342839991468737 0.4041209663056717 1.0 0.8895566555234558 14 P61978,Q04656,O00592,Q7LG56,Q10469 5 +Abnormality of iron homeostasis 0.5724238685423075 0.8285271288494401 0.4073720376647209 1.0 0.890687072195415 5 Q02241 1 +Primary amenorrhea 0.405360844080962 0.8270759285153688 0.4081940268545059 1.0 0.8909806857722452 31 Q16740,Q9BUK6,P51809,P16870,Q9Y6N7 5 +Abnormal cranial nerve physiology 0.3711888717050469 0.8253720318387381 0.409160408318016 1.0 0.8916059872207619 86 Q9Y5Y5,P01889,Q13501,Q13510,P07602,P48735,Q9H9S5,P51798,Q15043,Q86WC4 10 +Fetal ultrasound soft marker 0.418031058093893 0.8252808441327547 0.4092121646544493 1.0 0.8916059872207619 25 Q13501 1 +Abnormal renal tubule morphology 0.4192375918349049 0.8228547886616826 0.4105905756195449 1.0 0.8934911951246112 24 Q04446,P06280,P23786 3 +Type ii transferrin isoform profile 0.5697179271355416 0.8174632343136575 0.4136637516622397 1.0 0.8955117488923141 5 Q15904,O75787 2 +Ureterocele 0.5500510607682039 0.8073224159724726 0.419480752671451 1.0 0.8986150608114001 6 O14936 1 +Abnormally folded helix 0.4388728146853719 0.8021616941311472 0.4224594314227712 1.0 0.9030107419158548 18 P23786,P21964,P08754 3 +Xanthomatosis 0.740166086860522 0.8006481123818318 0.4233353891596061 1.0 0.9030107419158548 3 P01130 1 +Abnormality of the temporomandibular joint 0.6062112125639174 0.799880210432775 0.4237802045437542 1.0 0.9030107419158548 4 O75844 1 +Abnormal blood ion concentration 0.3531532026066363 0.7984465500202853 0.4246113989782394 1.0 0.9038567702855074 75 Q4J6C6,Q02241,Q15477,P21964,Q15904,O00192,Q13423,P10644,Q9Y487,P11166,P0DP25,P29992,P51798,Q15043,Q86WC4 15 +Exercise intolerance 0.3904414750383771 0.7944680925098264 0.4269229770931146 1.0 0.906322303914469 39 P13473,Q9Y2R0,Q9H2D1,P23786 4 +Extrapyramidal muscular rigidity 0.5215235226643994 0.7911693516028371 0.4288451736424703 1.0 0.9087008355611484 7 Q9H6K4 1 +Dilated fourth ventricle 0.3882223308969592 0.7905940140038755 0.4291809410635874 1.0 0.9087008355611484 48 O43505,P14543,P23786,Q14118,Q9Y487,Q9H9S5 6 +Miosis 0.7437550362610761 0.7884021060628698 0.4304615393103619 1.0 0.909205566883704 2 Q6XZF7 1 +Breech presentation 0.4917412581232782 0.7844115928683433 0.4327986382026028 1.0 0.909205566883704 10 O75718,Q9Y619,Q9H3S7,Q969X5,Q9UBM7 5 +Optic neuropathy 0.4131999960974274 0.7803672202213158 0.4351747566130659 1.0 0.9111229917542656 24 P01130,O43676,O96000,Q9Y6M9 4 +Vertebral wedging 0.733745298226755 0.7780441796760241 0.4365429685133761 1.0 0.9124307938509696 3 Q8WVQ1,Q96AY3 2 +Dilated third ventricle 0.5595649531935978 0.7761542922128143 0.4376578903058534 1.0 0.9134824934891984 5 O75787,Q9ULH0 2 +Hyperactive deep tendon reflexes 0.4889693422090838 0.7708450138904593 0.4407988024068814 1.0 0.9169966273659568 10 O75787,O00429,P11166 3 +Limitation of joint mobility 0.4121678709116458 0.7706786597883719 0.4408974240166752 1.0 0.9169966273659568 120 Q04446,P01889,O14979,P23786,Q7LGA3,P15586,P50402,Q8TAA9,Q9H6K4,P16278,P54802,O15460,Q96J02,P08236,Q9UBC1,P51688,Q04656,O75844,O94766,P48735,O00754,Q05086 22 +Abnormal trabecular bone morphology 0.5069611495380537 0.7695113317588689 0.4415898200909951 1.0 0.9171035457502532 8 Q04721,P22413 2 +Somatic sensory dysfunction 0.4170151767569399 0.7674791801645007 0.4427966671569301 1.0 0.917904358224187 124 O14773,P01889,P07602,P06280,P05067,Q9H6K4,Q8IV08,P54802,O15460,P07686,O15269,P11166,Q9NQ11,Q9BUK6,Q8NCH0,Q04656,O95831,Q06787,Q9Y619,P41440 20 +Male sexual dysfunction 0.4331007636873499 0.7662449407865168 0.443530572516484 1.0 0.917904358224187 18 Q9NZJ4,Q8WWQ0,O00592,Q06787,P07686 5 +Oral pharyngeal dysphagia 0.469947895688601 0.7656834552650196 0.4438646737542198 1.0 0.917904358224187 12 Q01105,P67870,Q13510 3 +Exostoses 0.5400363410394081 0.7650443290335989 0.4442451484515934 1.0 0.9182884151465424 6 P48735,Q04656 2 +Lung adenocarcinoma 0.5565622479344093 0.7640038934679281 0.4448649223849164 1.0 0.9186711128419838 5 P00533 1 +Visual field defect 0.3840500455020689 0.7629539058307788 0.445490886022214 1.0 0.9186711128419838 50 Q9Y5Y5,P04439,P01889,O15460,Q9Y287,Q9H6K4,Q8NHS3 7 +Broad nasal tip 0.3698974151203599 0.7629282762879285 0.4455061716770603 1.0 0.9186711128419838 63 P16278,O95831,P10644,P10586,Q9UPP1,Q7LGA3,Q9Y487,P98164 8 +Chondrosarcoma 0.5965517580149641 0.7626407441051493 0.4456776785490117 1.0 0.9186711128419838 4 P48735,Q92804 2 +Cerebellar cyst 0.3854982646027752 0.761787227051384 0.4461870049537708 1.0 0.9190789551581604 47 O43505,P14543,P23786,Q14118,Q9H9S5 5 +Blurred vision 0.7285442888461795 0.7598510688067232 0.4473436127612653 1.0 0.9210590105543084 3 P04439 1 +Lewy bodies 0.514212299042086 0.7586956309951807 0.4480346510429234 1.0 0.9216768672196264 7 P04062 1 +Urinary bladder sphincter dysfunction 0.4944141283905079 0.7565206233878435 0.4493371122207992 1.0 0.9231479233642998 9 P22626,Q12768,Q04446,Q06787 4 +Cns demyelination 0.4373308459500955 0.7544667050098783 0.4505690305925411 1.0 0.924470400019074 16 Q9H9P8,P07602 2 +Abnormality of circulating leptin level 0.5935854596651011 0.7512789309929894 0.4524848062750695 1.0 0.9261696134920054 4 O75844 1 +X linked dominant inheritance 0.4060564263346268 0.751127748978888 0.4525757771973659 1.0 0.9261696134920054 26 P13473,O14936,Q06787,P53701 4 +Impotence 0.4669228502138902 0.7498512475981846 0.4533442995837244 1.0 0.9267144185911388 12 Q9NZJ4,Q8WWQ0,Q06787,P07686 4 +Erectile dysfunction 0.4669228502138902 0.7498512475981846 0.4533442995837244 1.0 0.9267144185911388 12 Q9NZJ4,Q8WWQ0,Q06787,P07686 4 +Abnormality of the clitoris 0.4074360416606382 0.7497062607789485 0.453431635989344 1.0 0.9267144185911388 25 Q9Y5Y5,Q9Y619,P51809,Q9NP72,Q9UBM7,P53701 6 +Neurogenic bladder 0.4666282078336375 0.7483102848200385 0.4542730223637856 1.0 0.9271705198416068 12 Q04446,Q9NQ11,Q8TAA9 3 +Eeg with polyspike wave complexes 0.5018896057174251 0.746311643027442 0.4554791797369426 1.0 0.9280432284839728 8 Q14108 1 +Tongue nodules 0.7240029376254733 0.744055114226755 0.4568431327661337 1.0 0.9280432284839728 3 P98175 1 +Weight loss 0.3680434544922747 0.742056050288302 0.4580533765503136 1.0 0.9280432284839728 89 P42892,P01889,P15260,O15460,Q04656,Q13423,P04062,P10644,O75844,P07602,P38571,Q06136,Q92581 13 +Genu varum 0.4352448575960408 0.7420146095310672 0.4580784840175846 1.0 0.9280432284839728 16 Q6NUS6,Q8WVQ1,P22413,Q7RTS9,Q15643,Q9Y619 6 +Dyschromatopsia 0.5090793916428273 0.7359927514688276 0.4617351090568897 1.0 0.9280432284839728 7 Q9H6K4 1 +Sparse body hair 0.4636129212002746 0.7325525688624214 0.463831369054873 1.0 0.9280432284839728 12 Q14574,Q06787,P53634 3 +Postaxial foot polydactyly 0.4568332291435721 0.7323514206721197 0.4639541016034174 1.0 0.9280432284839728 13 O75845,Q9UBM7,P22694 3 +Abnormality of the 5th toe 0.4568332291435721 0.7323514206721197 0.4639541016034174 1.0 0.9280432284839728 13 O75845,Q9UBM7,P22694 3 +Respiratory tract infection 0.4846027880804521 0.7322949469795993 0.4639885628337998 1.0 0.9280432284839728 184 P14174,P01889,P15260,P04062,P00533,P07602,Q9Y487,P15586,P16278,P34059,P54802,P53634,Q13510,O00462,P10253,O15460,P08236,P51798,Q86WC4,Q9H9B1,P51688,P13051,P02786,P04066,Q99519,Q04721,O00754 27 +Abnormal pyramidal sign 0.4407781474139576 0.7290398681150643 0.4659772754750384 1.0 0.9280432284839728 146 O14773,Q04446,P01889,Q13501,Q6DKK2,P07602,Q9H6K4,P17900,Q9UBX1,P15289,P11166,Q9NQ11,P02792,Q9NUM4,O75787,Q15043,P04066,P35637,O00754,O95831,O00592,Q9Y619,P41440,Q9H9S5 24 +Congenital malformation of the right heart 0.4802954918298396 0.7285160645673238 0.4662977384301534 1.0 0.9280432284839728 10 P01889 1 +Abnormal nerve conduction velocity 0.3808628022173253 0.7283781896340962 0.4663821106359171 1.0 0.9280432284839728 49 Q9NZJ4,P15289,O43681,Q6PIJ6,O95831,P51149,Q13614,O15269,Q9Y619,P07602,Q7LG56,Q99519 12 +Truncal titubation 0.7193643403119798 0.7280109711853777 0.4666068703446497 1.0 0.9280432284839728 3 Q9NWX6 1 +Retinopathy 0.3813437548460044 0.7273477445193753 0.4670129571024386 1.0 0.9280432284839728 35 P01889,P22413,Q5H8A4,O75306,P07437,Q13049,Q8NHS3,Q99519 8 +Muscle hypertrophy of the lower extremities 0.4712125144833743 0.725812905782416 0.4679534740927016 1.0 0.9280432284839728 11 Q14118 1 +Hypoketotic hypoglycemia 0.4965853843491821 0.7221304017305749 0.4702143083157204 1.0 0.9280432284839728 8 P23786 1 +Hypoparathyroidism 0.4547971472081674 0.7213812493807075 0.4706749798432876 1.0 0.9280432284839728 13 P21964,Q08J23 2 +Hip pain 0.5459546102909578 0.7213515129321082 0.4706932706293347 1.0 0.9280432284839728 5 O75844 1 +Verrucae 0.7168189145620586 0.7192467766743604 0.4719888827915479 1.0 0.9280432284839728 3 Q8IWT6,P16615 2 +Sudden loss of visual acuity 0.7165502418054761 0.7183233954393691 0.4725579080467796 1.0 0.9280432284839728 3 O00255,P35222 2 +Bifid scrotum 0.5286306811204255 0.7172914553359929 0.4731942784449434 1.0 0.9280432284839728 6 Q96EK5,Q9UBM7 2 +Abnormal mitochondrial morphology 0.4602441210674551 0.714975122056723 0.4746244158787096 1.0 0.9280432284839728 12 Q13501 1 +Decreased number of large peripheral myelinated nerve fibers 0.4947072074075813 0.7135899829699578 0.4754807534548271 1.0 0.9280432284839728 8 Q9NZJ4,O15269 2 +Abnormal serum iron concentration 0.5834858463288803 0.7128784274420382 0.4759209892930127 1.0 0.9280432284839728 4 Q02241 1 +Nodular goiter 0.7147940841631684 0.7122958415541493 0.4762815985746478 1.0 0.9280432284839728 3 Q14145 1 +Hyperphosphatemia 0.714513361760204 0.7113336383256306 0.4768775112872281 1.0 0.9280432284839728 3 P10644 1 +Scapular winging 0.3987794154501372 0.7105764022828767 0.4773467704179235 1.0 0.9280432284839728 27 Q13501,Q9Y487 2 +Aplasia hypoplasia of metatarsal bones 0.4681372190080152 0.7103331507417386 0.4774975669876373 1.0 0.9280432284839728 11 Q8WVQ1,P10644 2 +Central diabetes insipidus 0.722266988987371 0.7094139704548352 0.4780676207488228 1.0 0.9280432284839728 2 P35222 1 +Hypoglycemic coma 0.4842259068932961 0.7085568294637743 0.4785995342612552 1.0 0.9280432284839728 9 Q13423 1 +Abnormal renal cortex morphology 0.3733166867305637 0.7080311791771771 0.4789258954080946 1.0 0.9280432284839728 56 P01889,Q96J84,P23458,P06280,Q14108,Q86WC4 6 +Abnormality of lower limb epiphysis morphology 0.4164652801572316 0.7062349054439061 0.4800420667466838 1.0 0.928191361923172 20 Q8WVQ1,O95831,Q7LGA3 3 +Poor wound healing 0.5255540758231395 0.7044923355944447 0.4811262214562433 1.0 0.9286883997524372 6 P04062 1 +Abnormal motor evoked potentials 0.7124868746835769 0.7043984374599696 0.4811846788112839 1.0 0.9286883997524372 3 Q9NZJ4 1 +Myopathic facies 0.4829687516131129 0.7026609058095344 0.4822670964555038 1.0 0.930016098072679 9 Q9BUK6,Q969X5,Q00577 3 +Cardiac arrest 0.3784614344823783 0.6997420415754262 0.484088416055392 1.0 0.932230525460984 36 P01130,P01889,O15460,P04062,P04899,P50402 6 +Atrophy degeneration involving the corticospinal tracts 0.4361513405917208 0.6995245070916184 0.4842243029213078 1.0 0.932230525460984 15 Q13501 1 +Pancytopenia 0.3791601232529097 0.6982333901968206 0.4850312480341037 1.0 0.9330568480133818 39 O00754,P04062,P10644,Q14108,Q86WC4 5 +Nuclear cataract 0.5235919019887347 0.6963490737181587 0.4862102475189489 1.0 0.934437278308087 6 P02792 1 +Cholestatic liver disease 0.499990827701913 0.6960135684123999 0.4864203325166545 1.0 0.934437278308087 7 Q04721,Q9UBM7 2 +Limited elbow extension 0.4429105250437413 0.6951872824782177 0.4869379412095376 1.0 0.934437278308087 14 Q7RTS9,Q04656,Q96J02,Q96L58,Q9H6K4 5 +Elevated gamma glutamyltransferase level 0.5775139057747238 0.6903935606094249 0.4899467251274307 1.0 0.9359746574064828 4 P38571 1 +Joint contracture of the hand 0.3732992136063743 0.6900675712893797 0.4901516952342648 1.0 0.9359746574064828 54 P42892,Q15392,Q8WVQ1,Q8IZA0,O75844 5 +Muscular dystrophy 0.3899712184335969 0.6892061614184032 0.4906935400048064 1.0 0.9359746574064828 30 O43505,O14979,Q14118,P50402,Q13049,Q9H9S5 6 +Generalized osteosclerosis 0.7080167581862954 0.6891686971049146 0.4907171131425034 1.0 0.9359746574064828 3 Q15392 1 +Premature pubarche 0.7163577759871039 0.688142825764115 0.4913628440495616 1.0 0.9359746574064828 2 O00255 1 +Decreased libido 0.7163577759871039 0.688142825764115 0.4913628440495616 1.0 0.9359746574064828 2 O00255 1 +Galactorrhea 0.7163577759871039 0.688142825764115 0.4913628440495616 1.0 0.9359746574064828 2 O00255 1 +Abnormal meningeal morphology 0.3896244134428118 0.6865458253315911 0.4923689774024442 1.0 0.9359746574064828 30 O75845,P21964,Q15904,Q5SZK8,O00192,Q8TAA9,Q9H9S5 7 +Knee clonus 0.7158205748052802 0.6862194788154816 0.4925747162886689 1.0 0.9359746574064828 2 Q8N0X7 1 +Abnormal periventricular white matter morphology 0.376534515749185 0.6845641930483045 0.493618968733216 1.0 0.9359894571363908 48 P15289,O75503,P07602,P17900,Q9H9S5 5 +Arthrogryposis multiplex congenita 0.3774654637608518 0.6815183563403241 0.4955435557231649 1.0 0.9387255384631268 41 Q15392,Q8NCH0,O75844,P04062,Q92581,Q9ULH0 6 +Long upper lip 0.7134031694869781 0.6775863625129968 0.4980339952917709 1.0 0.9407663946701356 2 Q96L58 1 +Abnormal morphology of the limbic system 0.4465841599099797 0.6772478564873218 0.4982487085741822 1.0 0.9407663946701356 13 P67870,Q86WC4 2 +Abnormality of the septum pellucidum 0.3740479192788902 0.6762611150597564 0.4988748763422608 1.0 0.9408780167815038 51 Q9H9B1,O43505,Q15392,Q08J23,Q14118,Q9Y6N7,P53701 7 +Autoimmune antibody positivity 0.4392046407663394 0.6746331242043213 0.4999088826042044 1.0 0.941698114853705 14 Q96J02,P15260 2 +Tibial bowing 0.5335956424927512 0.6722544854834576 0.5014216997882688 1.0 0.9441706527562648 5 Q7RTS9,Q32P28 2 +Abnormality of the radial head 0.4514226380330862 0.669106126343038 0.5034277822436422 1.0 0.9460589849656328 12 Q04721,P10644 2 +Sudden death 0.3871069481448171 0.6672379634011049 0.5046201454077339 1.0 0.9468438528956324 30 P01130,P01889,O15460,P04899,P50402 5 +Insulin resistance 0.3978280870934182 0.6647745898566493 0.5061946774253214 1.0 0.9474822961732396 23 O75844,P43304,O60266,Q9Y6M1 4 +Capillary hemangioma 0.4743901975869514 0.662578676157937 0.5076004308746263 1.0 0.9497365204658184 9 Q9UHX1,Q7LGA3,Q9UBM7,Q10469 4 +Abnormality of the phalanges of the toes 0.4015792008474537 0.6606147216661974 0.5088594255168017 1.0 0.9500534269435724 22 Q04721,Q8WVQ1,O75844,O14936,Q7LGA3 5 +Cerebral cortical atrophy 0.4007832621332561 0.659800638141666 0.5093817737674127 1.0 0.9500534269435724 119 Q9H9B1,O00754,Q9NUM4,Q13501,Q16625,P51970,Q5KU26,P04062,Q92673,Q9Y619,Q7LGA3,O14936,Q06787,P05067,Q92581,Q9NQ11,O75503,Q9H9S5 18 +Retinal atrophy 0.3760801490512803 0.6591871600713047 0.5097755910513548 1.0 0.9503708206434068 34 P04062,Q9HCM3,Q7LGA3,P04439 4 +Irregular menstruation 0.4912733883719765 0.6579663339781124 0.5105597643032342 1.0 0.9503708206434068 7 P10644 1 +Depressed nasal ridge 0.4006124991880486 0.6540830299193846 0.5130583140207823 1.0 0.9504613323581496 22 O00754,P16278 2 +Hyperconvex nail 0.4724515078686205 0.6535594648999833 0.5133956666473654 1.0 0.9504613323581496 9 P42892 1 +Intestinal malrotation 0.3753673051524366 0.6533499294762403 0.5135307105510187 1.0 0.9504613323581496 34 Q04721,Q15392,P21964,O00192,Q8NCH0,P98164,Q9UBM7 7 +Dilated cardiomyopathy 0.3739433901100987 0.6529390225873206 0.5137955904286406 1.0 0.9504613323581496 45 P16278,P23786,P13473,Q9H9S5,P53701 5 +Follicular thyroid carcinoma 0.6969371305749544 0.651845191677745 0.5145010449437764 1.0 0.9504613323581496 3 Q9UNW1,Q15437 2 +Hamartomatous polyposis 0.6969371305749541 0.651845191677744 0.514501044943777 1.0 0.9504613323581496 3 P20585,Q15437 2 +Death in adulthood 0.4173778339185631 0.6510050865003194 0.5150432034305561 1.0 0.9504613323581496 17 P05067 1 +Entropion 0.464167547389319 0.6504283254484131 0.5154155855697495 1.0 0.950776402958282 10 P01889 1 +Hepatic cysts 0.4891254947924246 0.6486417969397242 0.5165699328152624 1.0 0.9513967910229896 7 P23458 1 +Laryngomalacia 0.4138859868708303 0.6471069691729473 0.5175627151416653 1.0 0.951758269069014 18 Q6NUS6,P36543,P21964,O00192,P07602 5 +Cough 0.3860520344808658 0.6435114681115013 0.5198922758158666 1.0 0.9541814248625188 29 P01889,O15460,P04062,P10644,P41440 5 +Premature rupture of membranes 0.5104313910328104 0.6421621083598147 0.5207679328805463 1.0 0.9545091323774806 6 O75844 1 +Back pain 0.3892520215124324 0.6407692592097052 0.5216726082436853 1.0 0.9545091323774806 27 P51798,P50402,P01889 3 +Abnormality of chorioretinal pigmentation 0.5641491392871103 0.640735452241227 0.521694576396514 1.0 0.9545091323774806 4 Q9Y619 1 +Angioid streaks of the fundus 0.7029277464410608 0.6406059562957506 0.521778728737788 1.0 0.9545091323774806 2 P22413 1 +Abnormal factor ix activity 0.7029277464410612 0.6406059562957502 0.5217787287377882 1.0 0.9545091323774806 2 Q10469 1 +Abnormal circulating sex hormone concentration 0.393151512521201 0.6394906587752528 0.5225037885721449 1.0 0.954885799658009 24 P16870,Q13423,P51809 3 +Tinnitus 0.4122396296542925 0.6369446791645524 0.5241608786227365 1.0 0.956431324576704 18 O95831,Q15043,O43405 3 +Morphological abnormality of the corticospinal tract 0.4144437802454654 0.633270956623464 0.5265567160016238 1.0 0.9574316932550538 17 Q13501 1 +Joint laxity 0.3526822166531345 0.6302506780761674 0.5285305870525614 1.0 0.9580899695924988 85 Q04721,O00754,P16278,P34059,Q32P28,Q8WVQ1,Q9BUK6,Q8NCH0,Q04656,Q06787,Q9Y619,Q9Y487,P55795 13 +Writer s cramp 0.6898351145130267 0.6282592539711415 0.5298341192500358 1.0 0.9580899695924988 3 P02792 1 +Polyarticular arthropathy 0.6896673846077659 0.6277055697962233 0.530196835964118 1.0 0.9580899695924988 3 Q9UBC1 1 +Vasculitis 0.4426071307844461 0.6235417020600357 0.532928606992995 1.0 0.9598007570557568 12 O15460,P01889 2 +Osteopenia 0.3450415305645273 0.6227064468182734 0.5334774454674116 1.0 0.9602642977766792 80 Q04721,O00754,O75718,Q32P28,Q04656,O75844,P04062,P10644,P07602,Q9Y487,Q14108 11 +Germinoma 0.6880972565447127 0.6225301716427452 0.5335933107475928 1.0 0.9602642977766792 3 Q14145 1 +Mixed hearing impairment 0.4581281193828307 0.6214424776903151 0.534308530768723 1.0 0.9604358766951548 10 Q96L58,O00754,P22413,Q9NWM8 4 +Conjunctival hamartoma 0.6967499328498511 0.6191406314103682 0.5358237183336592 1.0 0.9606117231723206 2 Q15437 1 +Facial hemangioma 0.5196641553061521 0.6178066831035749 0.5367027775334217 1.0 0.9608544816133178 5 Q12768,Q10469,Q9UBM7 3 +Multiple lipomas 0.464708676906878 0.6176982366730787 0.5367742745640465 1.0 0.9608544816133178 9 O00255,P22413,Q9BUK6,Q8TAA9,P29992 5 +Hemorrhage of the eye 0.4411872873236173 0.6162324900182188 0.5377410879706941 1.0 0.9611255609483784 12 P36543,P22413,Q9Y487,P29992,P35222,Q92560 6 +Abnormal thrombosis 0.3870827159754487 0.6141153745557336 0.5391390892781907 1.0 0.9618012886669198 26 P48735,P10644,P38571,P01889 4 +Delayed ability to sit 0.4050519807487225 0.6112302309418772 0.5410471723815882 1.0 0.9632132543289568 19 Q14118,P10253 2 +Hypertrophic cardiomyopathy 0.3911645513754005 0.6105488351891198 0.5414983038929735 1.0 0.9634583029642906 115 P16278,P51688,P54802,P01889,O43676,P10253,Q13423,P13473,P06280,P15586,O96000,P53701 12 +Abnormal sternum morphology 0.4187092902849658 0.6089099251601722 0.5425841451328937 1.0 0.9634950416601904 137 P04062,Q7LGA3,Q9Y487,P50402,P16278,P34059,O75718,Q13510,Q96J02,P08236,Q08J23,Q9BUK6,Q8NCH0,Q04656,O94766,Q99519,Q04721,O00754,O95831,Q9Y619,Q92581 21 +Papule 0.3939137152472914 0.6088964380843354 0.5425930853420684 1.0 0.9634950416601904 22 O75844,Q07954,P01889 3 +Abnormal placenta morphology 0.455455486262415 0.6086672288676928 0.5427450330115515 1.0 0.9634950416601904 10 P16278 1 +Abnormality of upper limb joint 0.4135825372305232 0.6066960521380727 0.544052642622938 1.0 0.9647266679079176 133 P23786,Q7LGA3,P50402,Q9H6K4,Q9ULH0,P16278,P34059,Q13510,Q8IZA0,P10644,Q96J02,Q15392,Q8WVQ1,Q04656,O75844,P42892,Q04721,O95831,Q9Y619 19 +Methylmalonic aciduria 0.4614805879782248 0.6028286296206954 0.5466226988491687 1.0 0.9672741762190488 9 Q9NPF0 1 +Persistence of primary teeth 0.4773951601604056 0.598107235640107 0.5497683825995909 1.0 0.970118983516868 7 Q9H9B1 1 +Abnormal platelet morphology 0.498863063363993 0.5952276713219479 0.5516912959463927 1.0 0.972061620575002 6 O75845 1 +Hypertriglyceridemia 0.3855595563425971 0.5940407440756542 0.5524848620077054 1.0 0.972061620575002 25 O95470,P31751,P22830,P38571,P50402 5 +Abnormality of adrenal morphology 0.3749914506842546 0.5905119409226651 0.5548474826412024 1.0 0.9725300671573492 31 O75874,P22413,Q8WWQ0,O75844,P10644,P17612,P38571,P48735,Q9Y6N7 9 +Nocturnal hypoventilation 0.6776257302176782 0.5883796476333784 0.5562774954675569 1.0 0.9727304223409224 3 Q9H9S5 1 +Oral cavity bleeding 0.4750801330505014 0.5882180936140637 0.5563859141517666 1.0 0.9727304223409224 7 P10644 1 +Soft skin 0.4510070949370439 0.5874801173383929 0.5568813000367046 1.0 0.9730568206244788 10 O00754,Q04656 2 +Carious teeth 0.3659275544308414 0.5832117941615775 0.5597507324817053 1.0 0.9746142426136156 46 P16278,P34059,Q6P4Q7,P22413,P21964,O00192,Q9Y487,O60716,P51798 9 +Proptosis 0.3409459281745047 0.580790844680786 0.561381426216784 1.0 0.9748361596307888 70 O00754,O75718,Q32P28,Q8WVQ1,Q9NX62,Q5KU26,Q96J02,O75844,Q15043,P98164 10 +Craniosynostosis 0.3647124224848478 0.5805575217635286 0.5615387082836103 1.0 0.9748361596307888 49 O00754,Q08J23,P21964,Q8NCH0,Q9NX62,Q9Y619,P51798 7 +Retinal pigment epithelial mottling 0.6743654588091174 0.5778816780896348 0.5633440059663462 1.0 0.9758144702907134 3 Q9UG56 1 +Striae distensae 0.4483099464166316 0.5746830612142041 0.5655056653669854 1.0 0.9771552098148352 10 P10644,P22413,P17252,P17612 4 +Achilles tendon contracture 0.4209223811929126 0.5739772162746731 0.565983219088932 1.0 0.9771552098148352 14 Q9H9S5,Q08J23 2 +Pendular nystagmus 0.4714190097450506 0.5726401058993328 0.5668883986328406 1.0 0.9778145133230712 7 Q9P273 1 +Micromelia 0.3792205170162366 0.5674920374839216 0.570379934857145 1.0 0.978702361145175 27 O75718,Q7Z4L5,Q15392,P10644,P48735,Q9UBM7 6 +Mildly elevated creatine kinase 0.3776270934733812 0.567145031680588 0.5706156502201667 1.0 0.978702361145175 28 Q13501,Q9BUK6,Q9H9S5 3 +Limited elbow movement 0.3642259114665325 0.5660364431442912 0.5713690070377953 1.0 0.97907884161863 42 P23786,Q04656,Q96J02,Q7LGA3,P50402,Q9H6K4 6 +Hypoplasia of the uterus 0.4464551653408233 0.5659053764702219 0.5714581064972364 1.0 0.97907884161863 10 Q16740,P53701 2 +Talipes equinovarus 0.3576212203874228 0.5612952936941603 0.5745962493816363 1.0 0.982657676504103 93 Q9H9B1,O00754,Q15392,Q8WVQ1,O75845,Q7RTS9,Q5H8A4,P21964,Q8NCH0,Q9NWM8,O00192,Q9Y619,Q9Y487,P08236,Q8TAA9,Q9ULH0,O94766 17 +Developmental regression 0.4203268083125679 0.5606463656429614 0.575038636949837 1.0 0.982657676504103 142 O14773,Q9Y5Y5,P16278,Q92581,P01889,P15289,O95831,Q13510,Q04656,P07686,Q9H2C2,P07602,P06280,P17900,Q15043,O75503,Q99519 17 +Hepatomegaly 0.4798811850967215 0.5600639588659679 0.5754358126755785 1.0 0.982657676504103 195 P14174,Q16625,Q15904,P23786,P04062,P07602,P15586,P16278,P34059,P54802,P61916,Q07021,Q13510,P10253,P07686,Q96J02,P08236,P38571,P11166,Q14108,P51798,Q86WC4,Q9Y5Y5,P51688,O43676,O96000,P04066,Q99519,Q04721,O00754,Q9Y619,Q93100,O15118 33 +Hemiparesis 0.3968486740299256 0.5597777066138783 0.5756310715809825 1.0 0.982657676504103 19 Q9BVA1,Q04446,P01889,O00429,P11166,Q92560 6 +Macroorchidism 0.4894976160435399 0.5577805613415706 0.5769942380367741 1.0 0.9832826131131316 6 P38159 1 +Branchial cyst 0.6784850926672187 0.5573014966848132 0.5773214532871407 1.0 0.9834070275465564 2 Q9UHX1 1 +Joint hyperflexibility 0.3603912403339468 0.5544580999213076 0.5792653734184334 1.0 0.9835632659388488 52 Q04721,Q08J23,Q8WVQ1,P21964,Q04656,Q9Y619,Q92581 7 +Abnormal systemic arterial morphology 0.4477955087248335 0.5544212269181558 0.5792906022295192 1.0 0.9835632659388488 166 P01889,P04062,P07602,Q7LGA3,P05067,P17900,P16278,P06865,P61916,Q13510,O15460,P10253,P07686,P10644,P38571,P10619,Q9H9B1,P01130,P21964,Q04656,O75844,O94766,Q99519,P53701,O14678,Q06787,O15118 27 +Hyperostosis 0.4034547928623789 0.553813275401256 0.5797066419799068 1.0 0.9837939296066096 16 O00754,P10644,Q15043 3 +Mortality aging 0.3970454483786356 0.5487486087036273 0.5831779827047716 1.0 0.9862323333636192 124 Q9Y5Y5,P16278,O75718,Q15904,Q5SZK8,P51114,O75844,P07686,P04062,P07602,O96000,P38571,Q9H9S5,P05067,Q92581,Q86WC4,Q9Y6N7 17 +Dysphagia 0.4263732342365779 0.5484650284963737 0.5833726357902722 1.0 0.9862323333636192 148 P01889,Q13501,O75306,P04062,P07602,P55011,P15586,P18887,P05067,Q01105,P61916,Q13510,Q8IZA0,P67870,Q14108,Q9NQ11,Q9NZJ4,Q8N0X7,P02792,Q9Y5Y5,P09471,O75874,O00429,Q04656,P48735,Q99519,P35637,Q06787,Q92581,O15118,Q05086 31 +Accelerated skeletal maturation 0.409455955717705 0.5474113813873847 0.584096137810671 1.0 0.9869027499014827 15 Q8WVQ1,P10644 2 +Upper extremity joint dislocation 0.3786168414962625 0.5449179788595734 0.5858099303799111 1.0 0.9871819121602664 25 Q8WVQ1,P10644,Q9Y619,Q04721 4 +Stroke like episode 0.5005408660472286 0.5449052842206662 0.5858186617655197 1.0 0.9871819121602664 5 P00403,Q13586,P51970 3 +Congenital hepatic fibrosis 0.4565509819747075 0.543339113176777 0.586896338882166 1.0 0.9873034942534205 8 Q6NUS6,Q96HP0,Q06330,Q8IY17,O15078,Q8NCM8,Q15051 7 +Generalized onset seizure 0.3899275277725788 0.5401352976106498 0.5891037297366952 1.0 0.9873034942534205 119 Q9H9B1,P02792,P16278,Q08J23,Q13510,P04062,Q86WC4,P07602,Q8NHS3,Q92581,Q14108,O75503,Q99519 13 +Impaired vibratory sensation 0.3588517890792371 0.5400607128498989 0.5891551633506356 1.0 0.9873034942534205 35 Q9NZJ4,O14773,Q06787,Q9Y619,Q9NQ11 5 +Extrapyramidal dyskinesia 0.6617135506700411 0.5377876879652786 0.5907236329091565 1.0 0.9873076322989112 3 P11166 1 +Breast hypoplasia 0.4984456988259267 0.537064253675567 0.5912232315281125 1.0 0.9873076322989112 5 Q9Y619 1 +Skeletal dysplasia 0.3576747004637927 0.5347133959883384 0.5928480568272518 1.0 0.9873820515508628 53 Q04721,Q9Y5Y5,P16278,Q7Z4L5,Q8WVQ1,O95831,Q8WWQ0,P10619,Q99519 9 +Abnormality of carpal bone ossification 0.4395262742460355 0.533288275335148 0.5938340425737787 1.0 0.9886731866726948 10 Q8WVQ1,P22413,Q15643,Q96L58 4 +Arachnodactyly 0.3583440906225523 0.5312666867045328 0.5952339869716661 1.0 0.9886731866726948 36 P53634,P21964,O00192,Q8NCH0,Q9UPP1,P55795 6 +Contractures involving the joints of the feet 0.3766714921547202 0.5311915070560108 0.5952860777031042 1.0 0.9886731866726948 25 Q8IZA0,Q9H9S5,Q08J23 3 +Hypolipoproteinemia 0.4615066543284324 0.5308676933426995 0.5955104666278799 1.0 0.9886731866726948 7 Q15800,P38571 2 +Abnormal myeloid leukocyte morphology 0.3822652607573708 0.5262460521954488 0.5987172606492579 1.0 0.9917244421580464 114 P16278,Q14126,P01889,Q08J23,P61916,P15260,Q13510,P23458,P02786,P10644,Q96J02,P38571,P41440,O15118,Q86WC4,Q99519 16 +Proximal upper limb amyotrophy 0.4523655432230374 0.5251375981292925 0.5994875407786919 1.0 0.9918129737778808 8 O14979 1 +Abnormality of the musculature of the upper arm 0.4523655432230374 0.5251375981292925 0.5994875407786919 1.0 0.9918129737778808 8 O14979 1 +Wide cranial sutures 0.4442730957114473 0.5245070805984842 0.5999258963339376 1.0 0.9918129737778808 9 O75844 1 +Stroke 0.3593625659906769 0.52251824827618 0.6013095443021417 1.0 0.9930990931606478 34 O75844,P05067,P06280 3 +Abnormal circulating dicarboxylic acid concentration 0.3588289060321077 0.5197153748458128 0.6032619692429169 1.0 0.9935491965204896 46 Q02241,O75845,P23786,O14678,O14936,P11166,P48735,P41440,Q86WC4 9 +Abnormal metaphyseal trabeculation 0.4798020351154715 0.5195974112196674 0.6033442028108289 1.0 0.9935491965204896 6 Q04721 1 +Clonus 0.3585808131875801 0.5169738928381769 0.6051743835739796 1.0 0.9936051903506709 42 O75787,Q9Y619,P07602,Q9H9S5,Q15043,Q86WC4 6 +Proximal tubulopathy 0.3722664861340998 0.5169114867908964 0.6052179486559472 1.0 0.9936051903506709 27 O75380,Q9NPL8,O43676,O75306,O96000,Q7LG56,P98164,Q9Y6M9 8 +Molar tooth sign on mri 0.4564281871974208 0.50971387444742 0.610251931333261 1.0 0.9939873068805862 7 Q6NUS6,Q96KP1,Q8WXW3,P36405,O15078,Q2M1P5 6 +Flat acetabular roof 0.4771683669551296 0.5093366709323945 0.6105162579467163 1.0 0.9939873068805862 6 Q8WVQ1 1 +Posterior pituitary dysgenesis 0.4903095674313847 0.5069168140961472 0.6122131874662129 1.0 0.9941235327778654 5 Q9Y6N7 1 +Progressive microcephaly 0.3562825993201102 0.5069148800691122 0.6122145445405842 1.0 0.9941235327778654 50 P50897,Q5KU26,O14936,Q9Y487,O95721,P11166,Q6PJG6,Q15043 8 +Facial hypertrichosis 0.3393507755767908 0.5068503132957621 0.612259850727418 1.0 0.9941235327778654 67 Q9H9B1,P51688,P54802,Q08J23,Q9UPP1,P15586 6 +Deep plantar creases 0.4902808164678037 0.5068111596296081 0.6122873253842886 1.0 0.9941235327778654 5 P61978,Q9Y487 2 +Abnormality of the calf musculature 0.3812128571930505 0.5004358441280372 0.6167682196877311 1.0 0.998647718347408 21 Q8NCE2,Q9NZJ4,Q12768,Q14118,P43243,Q13049,Q9H9S5 7 +Generalized hypopigmentation of hair 0.4320453931119865 0.4984077953425305 0.6181966434656223 1.0 0.9993844207306412 10 P10644,Q05086 2 +Slender finger 0.3564470360982663 0.4975598412875724 0.618794314885005 1.0 0.9993844207306412 43 P53634,P21964,O00192,Q8NCH0,Q9UPP1,P55795,Q92581 7 +Primary adrenal insufficiency 0.3916651131700224 0.4968996832741941 0.6192597948872265 1.0 0.9993844207306412 17 Q6NUS6,Q9Y5Y5,Q13423,Q92560,O43716 5 +Long nose 0.4066651172565689 0.4966312290095453 0.6194491267283859 1.0 0.9993844207306412 14 Q92581 1 +Flared metaphysis 0.4003015995649417 0.4960558667393933 0.6198549955693746 1.0 0.9995267797912454 15 Q86WC4 1 +Decreased fertility in females 0.4374808593328362 0.4940921754522092 0.621241083574771 1.0 1.0 9 P51809 1 +Variable expressivity 0.3420355332962764 0.4923188749739003 0.622493938879773 1.0 1.0 86 Q9BVA1,Q9BUF5,Q9NUM4,O95470,Q8WVQ1,Q6PIJ6,Q15058,Q13510,O00429,P00374,Q14118,P07602,P43243,P11166,Q8NI60,P17900,Q9H9S5,Q00577 18 +Abnormal metabolic brain imaging by mrs 0.3923684661154955 0.4892689484313886 0.6246513016308499 1.0 1.0 16 P07602,O75306,P35610 3 +Stomatitis 0.3921856338818325 0.488211104546119 0.6254003198068121 1.0 1.0 16 P01889 1 +Pulmonary fibrosis 0.3754147693784253 0.4850849854600288 0.6276160621774212 1.0 1.0 22 Q8IZA0,P04062 2 +Renal tubular atrophy 0.519752754635849 0.4838700342302219 0.6284781081368167 1.0 1.0 4 Q8WUM0,P57740,Q96AX1 3 +Abnormal blistering of the skin 0.3707559496236733 0.4834860273155751 0.6287506785515027 1.0 1.0 24 Q14574,P51798,P01889 3 +Nonimmune hydrops fetalis 0.3608451492512316 0.4809120218587508 0.6305790281752053 1.0 1.0 31 P04062,P10619 2 +Abnormality of globe size 0.3285497588124323 0.4803219436272354 0.6309984878598951 1.0 1.0 77 O43505,Q9P273,Q9BUK6,P21964,Q5SZK8,Q9Y2Y6,Q14118,O14936,O00459,P11166,Q9H9S5,O94766,P53701 13 +Disseminated intravascular coagulation 0.441713543926436 0.4793513306179784 0.6316887109457516 1.0 1.0 8 P10644 1 +Ectopia lentis 0.414047718790086 0.4785552188555176 0.6322550823693411 1.0 1.0 12 Q03519,Q96L58,P29992,Q92560,Q12797 5 +Juvenile aseptic necrosis 0.4488104463310963 0.4783280737076812 0.6324167180102862 1.0 1.0 7 Q9Y619 1 +Arterial rupture 0.6419365164525975 0.4773407811696775 0.6331194756863334 1.0 1.0 3 Q9NWM8 1 +Tracheal stenosis 0.4334690755332513 0.4762795613023773 0.6338752244403842 1.0 1.0 9 Q5SZK8 1 +Demyelinating peripheral neuropathy 0.3774416921903205 0.4759806188264899 0.6340881856170004 1.0 1.0 21 Q9NZJ4,Q7LG56,O00462,P41440 4 +Abnormality of the epiphyses of the distal phalanx of finger 0.6521622347569118 0.4729686203031852 0.6362355668998969 1.0 1.0 2 P82673 1 +Congenital contracture 0.3528937126776401 0.4724803907149977 0.6365839351720051 1.0 1.0 49 Q15392,Q8NCH0,O75844,P04062,Q9H9S5,Q92581,Q9ULH0 7 +Bicornuate uterus 0.4074835621219302 0.4710945769715705 0.6375731976132801 1.0 1.0 13 P98164 1 +Dysarthria 0.45740755571967 0.4689992245924488 0.6390701902693454 1.0 1.0 182 O14773,Q13501,Q6DKK2,P04062,P07602,Q7KZN9,P15586,Q9H6K4,Q9UBX1,O75503,P98155,Q8IV08,P15289,P61916,P07686,P11166,Q14108,Q9NQ11,P02792,Q9Y5Y5,Q9NUM4,Q08J23,P35637,O00754,Q06787,P41440,O15118 27 +Headache 0.3288567929876575 0.4677043924036901 0.6399959995623214 1.0 1.0 78 Q04721,P01889,P23786,O15460,P04062,P10644,Q8TAA9,P05067 8 +Brittle hair 0.3951617548579555 0.4674641710149351 0.6401678203611669 1.0 1.0 15 O75844,Q9Y487 2 +Excessive salivation 0.3511085910341631 0.4664888283523408 0.6408656422864218 1.0 1.0 37 Q8N0X7,P01889,O75787,P55795,P15586,Q92581,Q05086 7 +Absent thumbnail 0.4657255215124805 0.465355640615526 0.6416767953635114 1.0 1.0 6 O14936 1 +Clitoral hypoplasia 0.4378289818129197 0.4628617817346163 0.6434634433988184 1.0 1.0 8 Q9Y619 1 +Hypoplastic labia minora 0.4378289818129197 0.4628617817346163 0.6434634433988184 1.0 1.0 8 Q9Y619 1 +Hypoplasia of the iris 0.4303914443009184 0.4626959409765029 0.6435823281502733 1.0 1.0 9 P98164 1 +Decreased methylcobalamin 0.512962518135706 0.4612009402119767 0.6446544472011979 1.0 1.0 4 O14678 1 +Tonic seizure 0.3632255138548595 0.4610381855885548 0.6447712090884825 1.0 1.0 28 P09471,Q01105,O14936,P67870,P07602,Q9H3S7 6 +Abnormality of the cerebrospinal fluid 0.4401098678819991 0.4607746158235691 0.6449603154064185 1.0 1.0 167 O43505,Q16625,O75306,P23786,P04062,Q14118,P07602,Q7KZN9,Q8TAA9,P15289,P51970,P10644,P08236,P11166,P51798,Q86WC4,Q9UBM7,P02792,Q15392,Q08J23,P21964,O43676,O00459,O96000,P07942,O94766,Q99519,P53701,O00754,Q04721,Q9Y6M9,O95831,O00192,Q15833,Q9H9S5 35 +Epidermal acanthosis 0.4170705675921761 0.459292823495342 0.6460239005915138 1.0 1.0 11 Q14574,P00533 2 +Seborrheic dermatitis 0.4364138379039976 0.4568841032777317 0.6477543506301378 1.0 1.0 8 P21964 1 +Serositis 0.3710894339415421 0.4564199782328424 0.6480880021539055 1.0 1.0 22 P14174,P01889 2 +Oculogyric crisis 0.4164126209808999 0.456161050965899 0.6482741712403999 1.0 1.0 11 Q01105,P67870,Q9NQ11 3 +Overhanging nasal tip 0.6345273352512971 0.4554559052713181 0.6487812834942237 1.0 1.0 3 P17612 1 +Aplasia hypoplasia of the sternum 0.4628055350986198 0.4542981775366176 0.6496142276127506 1.0 1.0 6 Q9Y619,P98175 2 +Anencephaly 0.3770895970785654 0.4541605832685995 0.6497132509695431 1.0 1.0 20 P21964,O43505,Q8TAA9 3 +Abnormal blood potassium concentration 0.3986881714344525 0.4539356313752957 0.649875156881417 1.0 1.0 14 Q13423 1 +Limitation of movement at ankles 0.4756408757855573 0.4538751622444326 0.6499186814943991 1.0 1.0 5 O75844 1 +Cavernous hemangioma 0.4751976280413357 0.4523005561069043 0.6510524753808244 1.0 1.0 5 Q8NCE2,P50570,Q15437 3 +Contractures of the joints of the lower limbs 0.340976448401886 0.4514719475430029 0.6516494388359186 1.0 1.0 62 Q86XL3,Q08J23,P23786,Q8IZA0,Q14118,Q7LGA3,P50402,Q9H9S5 8 +Open mouth 0.3481233855938205 0.4511634647836241 0.6518717394903137 1.0 1.0 35 Q86XL3,P61978,P04062,P10644,P67870,Q92581,Q10469 7 +Increased connective tissue 0.4350366412846169 0.4510822311668099 0.6519302836828387 1.0 1.0 8 O95831 1 +Advanced ossification of carpal bones 0.6321110156178193 0.4484137652281248 0.6538546092126571 1.0 1.0 3 Q8WVQ1 1 +Opisthotonus 0.362766077146464 0.4482212186954959 0.6539935506057482 1.0 1.0 27 P04062,P07602,P11117,P51970 4 +Focal segmental glomerulosclerosis 0.3730521715152254 0.4476397241075114 0.6544132293178755 1.0 1.0 21 Q14108,Q96J84 2 +Broad forehead 0.3506198548918093 0.4475844451864934 0.6544531311411468 1.0 1.0 47 Q04721,O00754,Q8NCH0,P22694,O14936,P98164 6 +Abnormal brainstem mri signal intensity 0.3661006471687809 0.4471157500096168 0.6547914876838479 1.0 1.0 23 O75380,O95831,Q9NPL8,O43676,O75306,O96000,Q9Y6M9 7 +Premature skin wrinkling 0.3785259526279139 0.4461888187857178 0.6554608589464723 1.0 1.0 19 O75844,Q9Y487 2 +Abnormality of the achilles tendon 0.3847324248007163 0.4452961847634664 0.6561057246600881 1.0 1.0 16 Q9H9S5,Q08J23 2 +Abnormal myeloid cell morphology 0.507899631547404 0.4445628060102046 0.6566357314334939 1.0 1.0 4 P41440 1 +Steppage gait 0.3649809642833722 0.4436979370348186 0.6572609871739659 1.0 1.0 24 Q13501,O15269 2 +Abnormality of bladder morphology 0.4020008694875788 0.442936411908337 0.6578117293266574 1.0 1.0 13 Q5SZK8,Q04656,Q9NWM8,Q02809,P16435,Q15056,Q9UIG0 7 +Pituitary adenoma 0.3959288625116388 0.4392796513940826 0.6604589166817172 1.0 1.0 14 P10644 1 +Mitochondrial respiratory chain defects 0.5062375564362629 0.4391516036863134 0.6605516897490062 1.0 1.0 4 Q4J6C6 1 +Abnormal tricuspid valve physiology 0.3682969398368434 0.4379858222845203 0.6613965609711627 1.0 1.0 22 P10644,Q15904 2 +Trichorrhexis nodosa 0.6267633295706541 0.4329995184513459 0.6650151196639653 1.0 1.0 3 Q15477 1 +Abnormal elasticity of skin 0.3235074339310773 0.4259741574647257 0.6701266768870029 1.0 1.0 72 Q9H9B1,O00754,Q15904,O75787,Q8NCH0,Q04656,O75844,P04062,P10644,Q9Y487,O96000 11 +Abnormal atrioventricular conduction 0.3795685714689529 0.4257829128267943 0.6702660390199251 1.0 1.0 17 P0DP25,P06280,P50402 3 +Pilomatrixoma 0.5011049514022499 0.4226046715703392 0.672583717652445 1.0 1.0 4 Q14145 1 +Prominent occiput 0.3789799970843488 0.4223523618684738 0.67276784394693 1.0 1.0 17 Q04721,Q96J02,P14543 3 +Horizontal eyebrow 0.4349103472839964 0.4222422055356188 0.672848238121152 1.0 1.0 7 P00533 1 +Polycystic kidney dysplasia 0.3787244659284712 0.4208639155708804 0.673854456038268 1.0 1.0 17 P21964,O00192,P23786 3 +Motor seizure 0.3752285669682053 0.419914537758801 0.6745478871501711 1.0 1.0 116 P04062,P07602,P55011,O75503,P16278,Q01105,Q13510,P07686,P67870,P11166,Q10469,Q9H9B1,Q08J23,P09471,O75787,O00429,O14936,Q99519,Q9Y619,Q8WWV3,Q05086,Q9H3S7,Q92581,Q6PJG6,Q5XKP0,Q8NHS3,Q00577 27 +Hyperreflexia in upper limbs 0.4086178148333757 0.4193263329803362 0.674977654119739 1.0 1.0 11 P02792 1 +Retinal hemorrhage 0.4341167065163012 0.4190900369996717 0.6751503316846499 1.0 1.0 7 P22413,Q9Y487,P36543 3 +Neoplasm of fatty tissue 0.3964515344750213 0.4146853171436553 0.6783722823484712 1.0 1.0 13 O00255,P22413,Q9BUK6,Q8TAA9,P29992 5 +Unilateral cleft lip 0.6325543916196605 0.4143319404916911 0.6786310251262402 1.0 1.0 2 Q2M1P5 1 +Olivopontocerebellar hypoplasia 0.4641635314209924 0.4136769244137854 0.6791107288059102 1.0 1.0 5 Q9H9S5 1 +Abnormality of the humeroradial joint 0.3959234537055487 0.4120108189156402 0.6803314934088744 1.0 1.0 13 Q04721,P10644 2 +Cogwheel rigidity 0.4319626447229434 0.4105635341653891 0.6813926073232435 1.0 1.0 7 O75787 1 +Skin pit 0.4001154791918405 0.4098182754422326 0.6819392589809792 1.0 1.0 12 P61978,P08754,Q07954 3 +Arrhinencephaly 0.3901522890440301 0.4088044515607368 0.6826831728031704 1.0 1.0 14 P21964,Q8TAA9 2 +Postaxial hand polydactyly 0.3746161224158988 0.4084504893836279 0.6829429723867264 1.0 1.0 18 O75845,P22694,O00459,Q13049,Q9UBM7 5 +Chorioretinal degeneration 0.4621616936414147 0.4067925379495404 0.6841603677971266 1.0 1.0 5 Q9Y619 1 +Chorioretinal atrophy 0.4621616936414147 0.4067925379495404 0.6841603677971266 1.0 1.0 5 Q9Y619 1 +Oval face 0.4308622197536236 0.4062242484078729 0.6845778388237429 1.0 1.0 7 Q96L58,O14936 2 +Spastic paraplegia 0.3363626907306494 0.4042721461338664 0.6860126056492102 1.0 1.0 62 O00754,Q8N0X7,Q04446,O95831,O75306,P04062,Q9Y619,Q7KZN9,P07942,P11166,Q9NQ11,Q9ULH0 12 +Ankylosis 0.4493382083386546 0.4042546281563991 0.6860254862432631 1.0 1.0 6 O75844,P22413,P08754 3 +Abnormal peripheral myelination 0.3423324245486577 0.4034338055408317 0.6866291217651677 1.0 1.0 35 Q9NZJ4,P15289,O43681,Q13614,O15269,P07602,Q7LG56 7 +Loss of ability to walk 0.3755168706357162 0.4022294998348339 0.6875151337069307 1.0 1.0 17 P43155,Q9H9S5,Q99519 3 +Corneal ulceration 0.4608069245357901 0.4021556889142416 0.6875694506335157 1.0 1.0 5 O75844 1 +Tapered finger 0.3448978317023216 0.3985591191736669 0.6902180890706702 1.0 1.0 42 Q9H9B1,P42892,Q96EK5,Q8NCH0,P23786,Q06136 6 +Multiple joint dislocation 0.4920385676666832 0.394000710463682 0.6935805147019531 1.0 1.0 4 O94766 1 +Muscular hypotonia of the trunk 0.3373900986522826 0.3924529133002093 0.6947235961442904 1.0 1.0 89 P19022,Q16625,O75306,Q9H270,P07602,P17900,Q9ULH0,Q2TAA5,Q86WC4,Q08J23,Q5MNZ6,O75880,Q9P0J1,O14936,O00459,Q15043,O00754,Q9H3S7,Q9NP72,Q6PJG6,Q5XKP0 21 +Abnormal tricuspid valve morphology 0.3962870818479885 0.3912217966120845 0.6956332983054871 1.0 1.0 12 P21964,P53701 2 +Femoral bowing 0.3959549146805879 0.3896147636186096 0.6968214334316929 1.0 1.0 12 O00754 1 +Abnormality of thalamus morphology 0.3600840480012847 0.3841449413024687 0.7008710237084599 1.0 1.0 22 Q9H9S5,P02792,O75306,P11166 4 +Paroxysmal involuntary eye movements 0.3600608164720544 0.3839935109751721 0.7009832570033137 1.0 1.0 22 O75380,Q9NPL8,O43676,O75306,O96000,P11166,Q9Y6M9 7 +Abnormal ciliary body morphology 0.4882302681485243 0.3822334706903055 0.7022881972630086 1.0 1.0 4 P29992 1 +Autoamputation 0.4422396319504362 0.3785564305152576 0.7050172815709399 1.0 1.0 6 O15269 1 +Episodic vomiting 0.399799444424458 0.3783014270123247 0.7052066854573305 1.0 1.0 11 Q2TAA5,P61978,Q9Y619,Q86YH6 4 +Azoospermia 0.3728897274207677 0.3780617901461877 0.7053846924262079 1.0 1.0 16 Q13423,P04062,P51809 3 +Hypertrichosis 0.3688040297749204 0.3769873760681408 0.7061829864248739 1.0 1.0 114 Q9H9B1,O00754,P16278,P51688,P54802,P53634,Q08J23,Q9UPP1,P15586,Q99519 10 +Uveal melanoma 0.6053068156033707 0.373650305210333 0.7086645021827687 1.0 1.0 3 P29992 1 +Mydriasis 0.6053068156033707 0.373650305210333 0.7086645021827687 1.0 1.0 3 P29992 1 +Inferior lens subluxation 0.6053068156033707 0.373650305210333 0.7086645021827687 1.0 1.0 3 P29992 1 +Photopsia 0.6053068156033707 0.373650305210333 0.7086645021827687 1.0 1.0 3 P29992 1 +Choroidal melanoma 0.6053068156033707 0.373650305210333 0.7086645021827687 1.0 1.0 3 P29992 1 +Gynecomastia 0.3545116666546198 0.3722395772012675 0.7097144815366543 1.0 1.0 24 P16870,Q06787,P31751,P51809 4 +Dental malocclusion 0.3508403862219104 0.3708517695860664 0.7107479398161862 1.0 1.0 28 P10644,P51798,Q5SZK8 3 +Paraplegia 0.3293987240012049 0.3700337579826115 0.7113573375966236 1.0 1.0 65 O00754,Q8N0X7,Q04446,O95831,Q8WWQ0,O75306,P04062,Q9Y619,Q7KZN9,P07942,P11166,Q9NQ11,Q9ULH0 13 +Narrow mouth 0.3298972683660323 0.3686676758226571 0.7123754450947088 1.0 1.0 85 Q04721,Q15392,Q8WVQ1,P21964,Q5SZK8,Q8NCH0,Q9NX62,O75844,P04062,Q9Y619,Q7LGA3,Q9Y487 12 +Acantholysis 0.4508189117826973 0.3685444887656227 0.7124672786185022 1.0 1.0 5 P98194,P01889 2 +Optic nerve hypoplasia 0.3575297546867466 0.3675271058539919 0.7132258768304041 1.0 1.0 22 P61978,Q15058,Q8WWQ0,O14936,Q9H9S5,Q9Y6N7 6 +Reticulocytosis 0.381219073400286 0.3622839853670228 0.7171398243468743 1.0 1.0 14 P51798,P11166 2 +Unsteady gait 0.333228728439213 0.3614427799989214 0.7177684726055902 1.0 1.0 61 O95831,O75787,Q04656,P43155,Q14118,Q9H2C2,P11166,P18887,Q9H6K4,Q10469,O75503 11 +Multiple joint contractures 0.3511746912330202 0.3587525344830549 0.7197802239992663 1.0 1.0 26 O75844,Q15043,P41440 3 +Abnormal hdl cholesterol concentration 0.48004760256968 0.357468215363572 0.7207413168814734 1.0 1.0 4 P38571 1 +Abnormal sacrum morphology 0.3384884658028753 0.3567179830056484 0.721302941593851 1.0 1.0 38 Q08J23,P53701,P04066,P01889 4 +Hypophosphatemia 0.4120014514827615 0.3565498358273781 0.7214288373749651 1.0 1.0 8 P22413,P51798 2 +Hyperplasia of the maxilla 0.6107977437550322 0.3539684067210263 0.7233625601537195 1.0 1.0 2 Q96CW1 1 +Neuronal loss in the cerebral cortex 0.4458452995298954 0.3522002961749701 0.7246880548454744 1.0 1.0 5 Q13501 1 +Increased sulfur amino acid level in urine 0.434686917880423 0.3517737679798811 0.7250079328470895 1.0 1.0 6 Q4J6C6,O14678 2 +Stuttering 0.5959161740999387 0.34901108399748 0.7270809883491403 1.0 1.0 3 P00403,Q96KG9 2 +Testicular atrophy 0.4446236559139728 0.3482273001974988 0.7276694867275955 1.0 1.0 5 P00492,O76024,Q9NX24,P54098 4 +Leukopenia 0.3373303519624815 0.3479360509341873 0.7278882100784805 1.0 1.0 54 P04062,P10644,Q15904,Q14108 4 +Abnormal bleeding 0.3758505052183611 0.3434732690713669 0.7312424472312817 1.0 1.0 122 P01889,Q16625,P23786,Q4KMQ2,P04062,Q9Y487,P05067,P11117,P17301,Q86YV9,O15460,Q9NWM8,P10644,P17612,P29992,P51798,Q14108,Q10469,P21964,Q8NCH0,Q04656,O75844,Q99519,Q02241,O00192,Q6YHK3,Q15833 27 +Flank pain 0.6062315337093813 0.341970999801789 0.7323727167822347 1.0 1.0 2 P27797 1 +Deep palmar crease 0.3918367195193253 0.3419161180891827 0.7324140194105611 1.0 1.0 11 P61978,Q9Y487,P42345 3 +Abnormal glycosylation 0.3501631957635298 0.3403114606918784 0.7336219873006018 1.0 1.0 23 Q2TAA5,Q15904,O75787,Q8N511,Q9Y487,Q10469 6 +Periauricular skin pits 0.3967659950326999 0.3399041839619469 0.7339286857012386 1.0 1.0 10 Q07954,P08754 2 +Areflexia 0.3520852758753656 0.3341109539475651 0.7382958345285582 1.0 1.0 104 O43505,O95831,Q13501,O75787,Q13510,P10253,P51114,Q14118,O15269,P41440,Q9H6K4,Q9H9S5 12 +Protruding ear 0.3370456135525606 0.3331540883061777 0.7390179725382959 1.0 1.0 51 O43505,Q08J23,Q8NCH0,Q14118,Q06136,Q9H9S5 6 +Abnormality of the menstrual cycle 0.3321823806759855 0.3321180089929615 0.7398001520072799 1.0 1.0 59 Q16740,Q9BUK6,P31751,O75844,P10644,P51809,P16870,Q9Y6N7 8 +Abnormality of blood circulation 0.3210510150592904 0.3295659265287187 0.7417279721028316 1.0 1.0 81 P17301,P01889,P21964,P23786,O75844,P04062,P10644,Q9Y487,Q6YHK3,P05067 10 +Delayed menarche 0.428260680394495 0.3294675524960873 0.7418023155013271 1.0 1.0 6 O75844,O00429 2 +3 methylglutaconic aciduria 0.383345396615815 0.3294371669011571 0.7418252790441526 1.0 1.0 12 Q9H6K4,Q5XKP0,Q3ZCQ8 3 +Cystic liver disease 0.3942199672281501 0.3289307116408272 0.7422080602621719 1.0 1.0 10 P23458,Q6NUS6,Q7Z4L5 3 +Abnormality of the abdominal wall 0.4024204610247201 0.3288835915558852 0.7422436770833798 1.0 1.0 145 Q9Y487,P16278,P34059,Q32P28,P51970,Q5SZK8,O00462,Q9NWM8,P08236,P98164,Q9UBM7,Q9H9B1,P09471,Q8WVQ1,P21964,Q8NCH0,Q04656,O75844,O14936,O94766,P04066,Q99519,Q04721,O00754,O00192,O14678 26 +Adrenal hypoplasia 0.3939552752664321 0.3277940509323894 0.743067385704735 1.0 1.0 10 O75844,Q9Y6N7 2 +Decreased circulating acth level 0.4097441855593129 0.3253077192437792 0.7449481892134173 1.0 1.0 7 P10644,Q92560 2 +Limited knee extension 0.5863985493447128 0.3249199345499084 0.7452416691901105 1.0 1.0 3 Q04656 1 +Aplasia hypoplasia of the skin 0.322271591636924 0.322975374092462 0.746713892082947 1.0 1.0 67 Q15392,P53634,Q8NCH0,O75844,P10644,Q07954,P53701 7 +Cone shaped epiphysis 0.3616148534159642 0.3226523007735767 0.7469585799894642 1.0 1.0 17 O95831,P10644,Q7Z4L5 3 +Myoglobinuria 0.3778637327985318 0.3221946857629008 0.7473052101624211 1.0 1.0 13 P23786 1 +Abnormal circulating apolipoprotein concentration 0.5844558284864442 0.3201146325890298 0.7488814336462863 1.0 1.0 3 Q9Y487 1 +Abnormal cutaneous elastic fiber morphology 0.5844558284864442 0.3201146325890298 0.7488814336462863 1.0 1.0 3 Q9Y487 1 +Abnormal subcutaneous fat tissue distribution 0.5844558284864442 0.3201146325890298 0.7488814336462863 1.0 1.0 3 Q9Y487 1 +Prominent veins on trunk 0.5844558284864442 0.3201146325890298 0.7488814336462863 1.0 1.0 3 Q9Y487 1 +Quadriceps muscle weakness 0.4081102495623567 0.3192487134751373 0.7495379200186401 1.0 1.0 7 Q7LG56,Q13049 2 +Abnormality of adrenal physiology 0.3349347737214927 0.319104236143266 0.7496474714857304 1.0 1.0 40 Q6NUS6,Q9Y5Y5,P17252,O95470,O00255,Q13423,P10644,P51809,P38571,P17612,P82663,Q92560,O43716,P35222 14 +Aplasia of the semicircular canal 0.5832885545405617 0.3172459723050018 0.75105696925805 1.0 1.0 3 P62070,P22681 2 +Morphological abnormality of the vestibule of the inner ear 0.5832885545405617 0.3172459723050018 0.75105696925805 1.0 1.0 3 P62070,P22681 2 +Abnormality of cardiovascular system electrophysiology 0.3759328532854493 0.3171280101514114 0.7511464719492289 1.0 1.0 124 P42892,P01130,P53701,Q9Y5Y5,P01889,P51970,P23786,P10253,O15460,P13473,P04062,P07602,P06280,P50402,P04899,Q07954,Q99519 17 +Thoracic kyphoscoliosis 0.4238757415372992 0.3145139719860407 0.7531307063695849 1.0 1.0 6 O75844 1 +Aggressive behavior 0.3304658555331272 0.3134873871169179 0.7539104017500877 1.0 1.0 89 Q9H9B1,P54802,Q9NUM4,Q13501,Q6DKK2,O00462,Q06787,P55795,P11166,Q9NQ11,O75503,Q9UBM7 12 +Abnormal head movements 0.3851945284926762 0.3120935196870611 0.754969451292449 1.0 1.0 11 P35637,P11166 2 +Arm dystonia 0.4331531884727986 0.3117559676568437 0.7552259900570524 1.0 1.0 5 P02792 1 +Aplasia hypoplasia of the optic nerve 0.3420115851798061 0.3074232558220352 0.758521229098563 1.0 1.0 28 P61978,Q15058,Q8WWQ0,O14936,O95721,Q9H9S5,Q9Y6N7 7 +Abnormal pelvis bone morphology 0.4215951488132233 0.3068252205816634 0.7589764103377921 1.0 1.0 6 Q15643,Q7RTS9,Q04656,P16435 4 +Hypoplasia of the brainstem 0.3377348361016165 0.3045676527434343 0.7606954595513367 1.0 1.0 31 Q96EK5,O43505,O14936,Q9H9S5,P98155 5 +Gray matter heterotopia 0.3340916638984708 0.3028084137377785 0.7620358710453707 1.0 1.0 33 Q2TAA5,Q86XL3,O43505,Q9BVA1,P61978,Q15058,Q06787,P07942,Q9H9S5,Q9UBM7 10 +Abnormal nephron morphology 0.3228256809467479 0.3009720044207967 0.7634358425426946 1.0 1.0 65 Q04446,P01889,Q96J84,P23786,P23458,P06280,Q14108 7 +Sarcoma 0.3157252064346716 0.3000957477229148 0.764104122641367 1.0 1.0 70 Q15392,Q13501,P10644,P48735,Q07954 5 +Nasal regurgitation 0.576146220619357 0.3000007229667777 0.7641766041607145 1.0 1.0 3 Q9BUF5 1 +Abnormal female reproductive system physiology 0.3156798402268223 0.2991181073898235 0.7648499307204095 1.0 1.0 79 P01889,Q16740,Q9BUK6,P31751,O00592,P10644,O75844,P51809,P16870,Q9Y6N7 10 +Abnormality of the ankles 0.3332667671877067 0.2984874733768092 0.7653311354254098 1.0 1.0 51 O00754,O75787,O75844,Q14118,P07602,Q15043 6 +Abnormality of temperature regulation 0.3666922765185721 0.2978625812393782 0.7658080481533274 1.0 1.0 118 P14174,P01889,P15260,P23786,Q9H270,P07602,P06280,P35610,Q2TAA5,Q13510,O15460,P10253,P10644,P38571,P51798,Q9NQ11,Q9UBC1,Q04656,O14936,Q15833,Q05086 21 +Basal ganglia gliosis 0.3968253968253922 0.2972601636733585 0.766267892513373 1.0 1.0 8 P08559,P37198,O43819,P55265,O75306,P36776,Q9BU61 7 +Absence of secondary sex characteristics 0.4284071597077443 0.2971230165290606 0.7663725927754976 1.0 1.0 5 P51809 1 +Abnormal aortic valve morphology 0.3334343917365867 0.2962354116654456 0.7670503072091654 1.0 1.0 44 P01889,P21964,O75844,P04062,P06280 5 +Renal cortical microcysts 0.5874294923448797 0.2951645814485354 0.7678681571636283 1.0 1.0 2 Q8TD19 1 +Inability to walk 0.3433105781720063 0.2941884871799633 0.7686138775028861 1.0 1.0 100 Q9BUK6,O75787,Q13510,O00592,O15269,P11166,Q9H9S5,Q92581,Q15043,O75503,Q99519 11 +Infection related seizure 0.3408622103977806 0.2926156031715087 0.7698159859513434 1.0 1.0 27 P05067,P09471,O14936,P11166 4 +Centrally nucleated skeletal muscle fibers 0.3807454459968074 0.2924081717031861 0.7699745610128743 1.0 1.0 11 Q13049,P51114 2 +Abnormal cartilage morphology 0.3624280885628165 0.2909194539109239 0.7711129224361053 1.0 1.0 15 P48735,O75874,Q7LGA3,P08754 4 +Bifid uvula 0.3326130099887022 0.2891396977043968 0.7724744759553013 1.0 1.0 44 Q14118,Q9Y619,O43505,Q15392 4 +Nonprogressive cerebellar ataxia 0.5706609349811846 0.287121089119573 0.774019604928305 1.0 1.0 3 Q4G0N4,Q69YN2 2 +Myalgia 0.3308350484890063 0.2867491627332103 0.7743043911237719 1.0 1.0 54 P01889,Q9BUK6,P21964,O15460,P23786,Q06787,P06280,Q9H9S5 8 +Abnormal atrioventricular valve morphology 0.3323031837541347 0.2864650859738116 0.7745219308109395 1.0 1.0 44 Q9NZJ4,P22413,P21964,O00192,Q15056,O75844,P04062,Q06787,P55795,O94766,Q96L58,P53701 12 +Chylothorax 0.4549852190271497 0.2863443715505941 0.7746143766019733 1.0 1.0 4 Q06124,P22681,P52732 3 +Retinal telangiectasia 0.5701694805021518 0.2859828230853615 0.7748912775737857 1.0 1.0 3 O75306 1 +Bilateral tonic clonic seizure 0.3425770639261524 0.2859628889436672 0.7749065454699631 1.0 1.0 100 Q9NUM4,Q13501,P27544,O75787,Q13510,P07686,P04062,O14936,P07602,P67870,P11166,Q92581,Q05086 13 +Weakness of facial musculature 0.3159231646351451 0.2854117008427255 0.7753287442105419 1.0 1.0 69 Q9Y5Y5,Q13501,Q9BUK6,Q13510,P51798,Q15043,Q9H9S5 7 +Aplasia hypoplasia of toe 0.3320073227358466 0.2839120186406269 0.7764778057935022 1.0 1.0 44 P10644,Q7LGA3,Q13510,Q9NX62 4 +Abnormal aortic arch morphology 0.3698120137298785 0.283325828073706 0.7769270801425765 1.0 1.0 13 Q9UHX1,P21964,O00192,O00459 4 +Lower limb spasticity 0.3429740218787474 0.2758110731248748 0.7826931783625002 1.0 1.0 101 Q04446,Q6DKK2,O75306,P04062,P07602,Q7KZN9,Q9H6K4,Q9ULH0,P11166,Q9NQ11,Q9NZJ4,Q8N0X7,Q9Y5Y5,O75787,P07942,Q99519,P35637,O00754,O95831,Q9Y619 20 +Abnormal eyelid physiology 0.3857821551107636 0.2756865126813138 0.782788855659263 1.0 1.0 9 P02792 1 +Deep philtrum 0.3480703759347553 0.2755124126618585 0.7829225907719808 1.0 1.0 20 Q7LGA3 1 +Abnormality of the periorbital region 0.3084039662580576 0.273683515880761 0.7843278466850179 1.0 1.0 73 Q9Y5Y5,Q08J23,Q9UPP1,Q7LGA3,P98164,Q99519 6 +Abnormal circulating phenylalanine concentration 0.5780284716626319 0.2733796963545319 0.7845613585140336 1.0 1.0 2 P35270 1 +Focal t2 hyperintense brainstem lesion 0.3474898105138574 0.2720378617432064 0.7855929072801848 1.0 1.0 20 O75380,Q9NPL8,O43676,O75306,O96000,Q9Y6M9 6 +Leukocytosis 0.3300222181202079 0.2711535297547548 0.786272952333521 1.0 1.0 33 P23458,P10644,P15260 3 +Myositis 0.3758015436189295 0.2708244007612339 0.7865260918752512 1.0 1.0 11 P01889 1 +Sclerocornea 0.3584661791934644 0.2703717354117554 0.7868742824964321 1.0 1.0 15 Q9P273,Q9UBM7,P53701 3 +Left ventricular systolic dysfunction 0.3843335388380902 0.2699859894492015 0.7871710322958205 1.0 1.0 9 O75844,P22413 2 +Abnormality of the musculature of the thigh 0.3842470185186704 0.2696463827096215 0.7874323133217187 1.0 1.0 9 O14979 1 +Abnormally lax or hyperextensible skin 0.3299148370315905 0.2678531974853788 0.7888123206252877 1.0 1.0 51 Q9H9B1,Q15904,O75787,Q8NCH0,Q04656,P04062,Q9Y487,O96000 8 +Posterior embryotoxon 0.3389624231099004 0.2668996168069155 0.7895464516900743 1.0 1.0 23 Q04721,Q9Y5Y5,Q7LGA3,P53701 4 +Abnormality of the hepatic vasculature 0.3620061866259687 0.2652226294197138 0.7908379631923097 1.0 1.0 14 Q96J02,P38571 2 +Stereotypy 0.3140966188141439 0.2651627665048382 0.7908840765314213 1.0 1.0 80 Q9H9B1,Q9NUM4,Q08J23,Q13501,P61916,Q06787,P67870,P11166,Q92581,Q05086 10 +Abnormality of corneal size 0.3299940071723854 0.2638949766918032 0.7918608465040609 1.0 1.0 47 Q96EK5,O43505,Q9P273,O75845,Q5H8A4,Q9NP72,Q8NCH0,Q9NWM8,P07437,Q14118,Q96L58,Q9H9S5 12 +Broad distal phalanx of finger 0.3923681872168171 0.2625371884771251 0.7929073182730328 1.0 1.0 7 Q7LGA3 1 +Abnormal circulating sulfur amino acid concentration 0.3783750755737736 0.2623709458263502 0.7930354701437141 1.0 1.0 10 P41440 1 +Underdeveloped nasal alae 0.3356092617594985 0.2619974344658563 0.793323420124604 1.0 1.0 28 Q5KU26,Q5SZK8 2 +Abnormal fear anxiety related behavior 0.3770202089633447 0.2619695963403891 0.7933448824151477 1.0 1.0 129 Q13501,Q6DKK2,Q7LGA3,P06280,P55011,P17900,O75503,P10644,P55795,P11166,P29992,Q9H9B1,Q8N0X7,Q9NUM4,Q9BUK6,P21964,Q8WWQ0,Q7LG56,Q68CQ7,P35637,O00754,Q92804,O00192,O00592,Q06787,Q9H3S7,Q00577 27 +Arnold chiari malformation 0.3376621911995524 0.2619613938660777 0.7933512062862769 1.0 1.0 25 Q04721,O00754,Q15043,Q8TAA9 4 +Dicarboxylic aciduria 0.3364441073449373 0.2618715180016223 0.7934204988757529 1.0 1.0 27 Q9NPF0,Q9H9P8,P23786,O14678,P48735 5 +Atresia of the external auditory canal 0.3476938097559168 0.2616740173078135 0.7935727738994267 1.0 1.0 19 Q9Y619,Q5SZK8 2 +Hand polydactyly 0.3291580025851582 0.2614195553077602 0.7937689782648607 1.0 1.0 43 Q7Z4L5,O75845,P21964,O00192,P22694,Q9UPP1,O00459,Q13049,Q9UBM7 9 +Hypoventilation 0.3515916800398449 0.2609367522779534 0.7941412821398208 1.0 1.0 16 O75380,P61978,O75306,Q9H9S5,Q00577 5 +Neck muscle weakness 0.3433239808293438 0.2604963800505615 0.7944809072582708 1.0 1.0 21 P35637,P07602 2 +External ear malformation 0.3474300996722216 0.2601451420724143 0.7947518179423168 1.0 1.0 19 Q8IWT6,Q9Y5Y5,P08754,Q5SZK8,Q8NCH0,P07437 6 +Dysphonia 0.3247312542989093 0.260125640700666 0.7947668601221776 1.0 1.0 35 Q13510,Q99519 2 +Uveitis 0.3720098333241876 0.2544888558271218 0.7991179125192243 1.0 1.0 11 P01889 1 +Abnormal c reactive protein level 0.3900372660446844 0.2544105042597154 0.799178436659669 1.0 1.0 7 P14174 1 +Cystic hygroma 0.3763122476446731 0.2539418574747211 0.7995404768520582 1.0 1.0 10 Q14739,Q96S52,P61978,Q02750,Q15643,Q06124,P62070,Q99567,P22681 9 +Absence of pubertal development 0.4137627943633591 0.2537696904331256 0.7996734905941407 1.0 1.0 5 O75844 1 +Immunodeficiency 0.3082177761192951 0.2521689671622408 0.8009104637326869 1.0 1.0 72 Q8IWT6,O00754,Q9Y2Q5,P14174,Q15477,P15260,P21964,O00192,P13051,P02786,Q10469 11 +Atypical absence seizure 0.4415423776056636 0.2513749362427087 0.8015242436769141 1.0 1.0 4 Q05086 1 +Limb fasciculations 0.4410104810534743 0.2500396299512021 0.8025567015087782 1.0 1.0 4 Q92734,Q16637,P04792 3 +Abnormal platelet aggregation 0.4119106575569023 0.2484879895295169 0.8037568616965656 1.0 1.0 5 Q86YV9 1 +Inflammation of the large intestine 0.3481506826852351 0.2477862473754019 0.8042997961756841 1.0 1.0 17 Q15833,P23458,Q15477,P01889 4 +Decreased circulating androgen concentration 0.3622912419565126 0.247780159568007 0.8043045066960011 1.0 1.0 13 P16870,P51809 2 +Profound global developmental delay 0.3466051565077726 0.2462963228128925 0.8054528562605816 1.0 1.0 18 Q9Y5Y5,Q92581,P55011 3 +Aplasia hypoplasia involving the metacarpal bones 0.324887790662874 0.2454769380010562 0.8060871627965396 1.0 1.0 34 Q32P28,P10644,Q9NX62 3 +Anteverted ears 0.4391292663262521 0.2453470343668994 0.8061877362182521 1.0 1.0 4 O15347,Q6NXR4,P27635 3 +Hypoplasia of the ear cartilage 0.5651356432984119 0.2453166689782873 0.8062112460384798 1.0 1.0 2 P57740 1 +Hypomethioninemia 0.5637926403438058 0.2425158105018362 0.8083805074426069 1.0 1.0 2 Q9H3L0 1 +Abnormal spermatogenesis 0.3458869311519604 0.2422717466981716 0.8085696046021462 1.0 1.0 18 Q13423,P04062,P51809 3 +Thick upper lip vermilion 0.373252465091511 0.2415466452573177 0.8091314687892137 1.0 1.0 10 O75845,Q08J23 2 +Ventricular tachycardia 0.352669858372602 0.2407032433936998 0.8097851250061103 1.0 1.0 15 P0DP25,Q14126,P04899,P23786 4 +Cyanosis 0.3398689740592534 0.2394500069472616 0.8107566576152934 1.0 1.0 21 O75844,P04066 2 +Elbow flexion contracture 0.3302305976525911 0.2388719813330214 0.8112048523558268 1.0 1.0 30 Q7LGA3,P23786,P50402 3 +Weakness of the intrinsic hand muscles 0.5481430393733638 0.2376872637570017 0.8121236626692401 1.0 1.0 3 Q6PIJ6 1 +Anisocytosis 0.3850424287447483 0.2372457518960644 0.812466144412967 1.0 1.0 7 O14936 1 +Abnormal odontoid tissue morphology 0.3267981686787509 0.2358166684001707 0.8135749333668438 1.0 1.0 48 P16278,P34059,P21964,Q6P4Q7,Q9UBM7,P53701 6 +Primary hyperparathyroidism 0.4345908250217305 0.2342210381447648 0.8148133831456081 1.0 1.0 4 P29992 1 +Complete atrioventricular canal defect 0.4066657573884322 0.2337860362812794 0.8151510906425472 1.0 1.0 5 P17252,P17612 2 +Urinary urgency 0.3553584663300826 0.2327616537509198 0.8159464909849663 1.0 1.0 14 P04062,O94898 2 +Inverted nipples 0.3702679382470778 0.2295834719094487 0.8184154513505004 1.0 1.0 10 Q2TAA5,P61978,Q9H6U8,P83436,Q10469,P56589 6 +Abnormal qrs complex 0.557346226161685 0.2293962129691805 0.8185609793083655 1.0 1.0 2 Q9BTV4 1 +Knee flexion contracture 0.3313819773681111 0.2269829872281913 0.8204369711557185 1.0 1.0 27 Q7LGA3,P23786 2 +Cutis laxa 0.3220539397287576 0.2264823167020545 0.8208263111729044 1.0 1.0 37 Q15904,O75787,Q04656,Q8NCH0,Q9Y487,O96000 6 +Malabsorption 0.3205578910808707 0.2255459343643309 0.8215545953271184 1.0 1.0 60 Q9Y5Y5,P14174,P01889,Q08J23,P06280,P38571 6 +Abnormality of the pubic hair 0.3813413045497216 0.2247524606910397 0.82217185074358 1.0 1.0 7 P51809 1 +Heat intolerance 0.4021089165027983 0.2213243475459472 0.8248398934198724 1.0 1.0 5 Q05086 1 +Slow decrease in visual acuity 0.3755187978296903 0.2188790126411422 0.8267442955643642 1.0 1.0 8 O75306,P35222,Q92560,O00429 4 +Pancreatic fibrosis 0.5386415996841432 0.2185395611295253 0.8270087378116131 1.0 1.0 3 Q6NUS6 1 +Severe muscular hypotonia 0.3214264750366538 0.2183535541788223 0.8271536507647692 1.0 1.0 34 Q9Y5Y5,O43505,O95831,Q01105,Q5H8A4,Q9NWM8,P67870,Q9H9S5 8 +Neck flexor weakness 0.3935191079713336 0.2175660517056934 0.8277672376621048 1.0 1.0 6 P35637,Q13049 2 +Blue irides 0.3655604906205661 0.2109783089035274 0.8329041973789588 1.0 1.0 10 P10644 1 +Lacrimal duct atresia 0.5468708031157568 0.2092290480685457 0.8342694371454622 1.0 1.0 2 Q9NX14 1 +Non midline cleft palate 0.3973284061971538 0.2085693428595555 0.8347844450634485 1.0 1.0 5 O60716 1 +Abnormal vitamin b12 level 0.3724107829836877 0.2079766059689931 0.8352472336928216 1.0 1.0 8 P41440 1 +Neuronal loss in basal ganglia 0.3965053763440925 0.2064067700830243 0.8364731829331071 1.0 1.0 5 Q9BU61,P42858,O75306,O43819 4 +Migraine 0.3266323908650804 0.205323153421778 0.8373196555861904 1.0 1.0 29 P05067,P01889 2 +Inappropriate laughter 0.3660855724651484 0.2006504797542987 0.8409718835371394 1.0 1.0 9 Q92581 1 +Abnormality of the hypothenar eminence 0.419779629131968 0.1998723835627209 0.8415803893460929 1.0 1.0 4 Q7Z392,Q9NRG9,Q96IJ6 3 +Pneumothorax 0.3736314244277686 0.1993686162337407 0.8419744082855547 1.0 1.0 7 Q96L58,Q8NCH0 2 +Inflammatory abnormality of the eye 0.321978867820028 0.1980179687612152 0.8430310050556482 1.0 1.0 44 P14174,P04439,P01889,P02786,P00533 5 +Aplasia hypoplasia affecting the fundus 0.320484247196491 0.1978425200023402 0.8431682774845375 1.0 1.0 33 P61978,Q15058,Q8WWQ0,Q86YV9,O14936,O95721,Q9H9S5,Q9Y6N7,Q99519 9 +Infectious encephalitis 0.3536902764811868 0.1955933968699152 0.8449284289908672 1.0 1.0 12 Q15833,Q9H9P8,P01889 3 +Dystrophic toenail 0.3918981331673711 0.1944844573246529 0.8457965646393892 1.0 1.0 5 O75844 1 +Abnormality of the posterior pituitary 0.3576333293420202 0.1944199869411849 0.8458470411837942 1.0 1.0 11 Q92560,P35222,Q8WWQ0,Q9Y6N7 4 +Microglossia 0.4170948404605482 0.1939741398318822 0.8461961307334869 1.0 1.0 4 Q9UBM7 1 +Abnormality of peripheral nerves 0.3193395322888216 0.1931623050270954 0.8468318589691723 1.0 1.0 57 Q9NZJ4,P15289,O43681,Q6PIJ6,O95831,P51149,Q13614,O15269,Q9Y619,P07602,O95721,Q7LG56,Q99519 13 +Chest pain 0.3355508163885505 0.1923797256779381 0.8474447723440595 1.0 1.0 19 P01889 1 +Patellar hypoplasia 0.5363953800698391 0.1904948142147799 0.8489214064444457 1.0 1.0 2 Q8N806 1 +Facial erythema 0.5363953800698388 0.1904948142147796 0.8489214064444459 1.0 1.0 2 O00170 1 +Abnormal circulating free fatty acid concentration 0.4141359849502835 0.1875923088195214 0.851196255880416 1.0 1.0 4 Q16836,O75431,P49748 3 +Polymicrogyria 0.3126263259287281 0.186627485704257 0.8519527148823776 1.0 1.0 84 Q9Y5Y5,Q9BVA1,O43505,Q96EK5,Q15392,Q08J23,Q01105,Q16625,P23786,P07437,Q14118,O00459,P67870,Q9Y487,P55011,O95721,Q9H9S5 17 +Delayed epiphyseal ossification 0.3887517895341126 0.1865235197771204 0.8520342363718161 1.0 1.0 5 Q9UG56 1 +Increased circulating prolactin concentration 0.3621528350948475 0.186350621838949 0.8521698121487147 1.0 1.0 9 Q9BUK6,Q92560,P35222 3 +Lens subluxation 0.4132082153309863 0.1856169454350742 0.8527451639641159 1.0 1.0 4 P29992 1 +Delayed ability to roll over 0.4125367110264103 0.1841948871166346 0.8538605703488695 1.0 1.0 4 P51970 1 +Slender build 0.3413295536152265 0.184146139968536 0.8538988108790799 1.0 1.0 15 P10644,P17612,Q3ZCQ8 3 +Recurrent bronchitis 0.3688455563012666 0.1840636461450928 0.8539635253452187 1.0 1.0 7 P00533 1 +Nausea 0.325783690335461 0.183551994647028 0.8543649258543837 1.0 1.0 25 P06280 1 +Choreoathetosis 0.3167248703109517 0.1835361212515747 0.8543773794439833 1.0 1.0 37 P02792,Q9H6K4,O14936,P11166 4 +Decreased adenosylcobalamin 0.5195928339464766 0.1833011468152344 0.8545617346149799 1.0 1.0 3 O14678 1 +Muscle abnormality related to mitochondrial dysfunction 0.3185473477603318 0.1828138070909957 0.8549441146933261 1.0 1.0 40 O75380,Q9UBX3,Q9NPL8,Q9BUK6,O43676,O75306,Q9Y606,O96000,Q7LG56,Q9Y2R0,Q9Y6M9 11 +Central nervous system cyst 0.3145018476827239 0.1825285433176252 0.8551679562662267 1.0 1.0 62 O43505,P14543,P23786,Q14118,Q9H9S5 5 +Abnormality of skin physiology 0.3473488411094207 0.1821440955302876 0.8554696442632135 1.0 1.0 111 P14174,P53634,P10321,P07858,P01889,Q92542,Q08J23,P21964,Q8NCH0,P22830,P02786,P23458,P00533,P38571,Q06136,Q07954 16 +Macroscopic hematuria 0.5299489658877194 0.1796779683820247 0.8574053906185022 1.0 1.0 2 P07741 1 +Polydactyly 0.3157369530968172 0.1780762189680274 0.8586631180318431 1.0 1.0 60 P17252,Q7Z4L5,P61978,O75845,Q9UHX1,Q5H8A4,P21964,Q12768,P22694,O00192,P98175,Q00577,Q9UPP1,O00459,P17612,Q13049,Q9UBM7,Q99519 18 +Abnormality of tibia morphology 0.3351013022095928 0.1777967036251062 0.8588826362302053 1.0 1.0 17 O95831,Q7RTS9,Q04656,Q32P28 4 +Hyperpituitarism 0.3270071248721766 0.1752887732445635 0.8608527328510003 1.0 1.0 22 P10644,Q9BUK6,P51809 3 +Sleep wake cycle disturbance 0.3786891971578426 0.1748499880566215 0.861197508518899 1.0 1.0 6 Q05086 1 +Spotty hypopigmentation 0.5267257587966623 0.1744721966358713 0.8614943795005976 1.0 1.0 2 Q15125 1 +Spotty hyperpigmentation 0.5267257587966592 0.1744721966358662 0.8614943795006016 1.0 1.0 2 O75531 1 +Oligospermia 0.5267257587966555 0.1744721966358603 0.8614943795006063 1.0 1.0 2 P16435 1 +Abnormal platelet function 0.3623157839948776 0.1735842840086999 0.8621921840487747 1.0 1.0 8 Q86YV9 1 +Motor axonal neuropathy 0.3321363811014833 0.1733365206687518 0.862386918804475 1.0 1.0 19 O95831,O15269 2 +Insulin resistant diabetes mellitus 0.3584974361257048 0.1732785354158007 0.8624324947294641 1.0 1.0 9 O75844 1 +Biventricular hypertrophy 0.5253827558420487 0.1723428648025441 0.8631679872336673 1.0 1.0 2 P36543 1 +Brachycephaly 0.3004544292371244 0.1707773027734943 0.8643988766374413 1.0 1.0 76 Q9H9B1,O00754,Q8NCH0,Q04656,P04066,P04062,P10644,P07437,Q05086,O00571,O94766,Q9ULH0,Q10469,Q10471,Q93009 15 +Increased laxity of ankles 0.5232339511146848 0.1689844324779226 0.8658088863819513 1.0 1.0 2 O95140 1 +Abnormal blood inorganic cation concentration 0.3185367774230611 0.1688699662099866 0.8658989233753731 1.0 1.0 44 Q4J6C6,P21964,O00192,P10644,P51798,Q15043,Q86WC4 7 +Abnormal branching pattern of the aortic arch 0.4048677064835529 0.1684136743961158 0.8662578511397068 1.0 1.0 4 O00459 1 +Ulnar deviation of finger 0.3571044133476821 0.1683538449300401 0.8663049161754899 1.0 1.0 9 Q9Y3E5,P28482,Q9Y2D4,Q9H2M9,Q96L58,Q15042,P46109,Q9UBM7 8 +Uterus didelphys 0.5224281493419285 0.1677403813042727 0.8667875265686358 1.0 1.0 2 O14974 1 +Horizontal ribs 0.5224281493419209 0.1677403813042608 0.8667875265686451 1.0 1.0 2 O75147 1 +Lethal skeletal dysplasia 0.5096722192369609 0.1666323443421734 0.8676593423866434 1.0 1.0 3 Q15643,Q8NCM8 2 +Absent hand 0.5088662009672122 0.1653288616825014 0.8686851430571625 1.0 1.0 3 Q9UBC2,Q96HP0 2 +Epiphyseal dysplasia 0.3627186306107841 0.164995420878597 0.8689475862699674 1.0 1.0 7 Q8WVQ1,Q7RTS9 2 +High anterior hairline 0.3225506230352976 0.1626259851754063 0.8708129261417445 1.0 1.0 25 P98164 1 +Abnormal ossification involving the femoral head and neck 0.3783580611304856 0.1612912305776089 0.8718640298184681 1.0 1.0 5 Q96L58,Q7RTS9 2 +Osteoporosis 0.2982336734880946 0.1608697084861575 0.8721960206553858 1.0 1.0 75 Q04721,P16278,P34059,Q8WVQ1,O75845,Q5H8A4,Q13510,Q8WWQ0,Q04656,P10644,Q9NPE3,P51809,P17612,Q7LG56,O94766 15 +Cerebellar atrophy 0.4049578282147799 0.1601790813530022 0.8727400072807057 1.0 1.0 161 O14773,Q13501,Q9H9P8,Q6DKK2,Q5H8A4,P43155,Q9H270,P18887,Q9H6K4,Q9UBX1,O75503,P98155,Q8IV08,O75845,P51970,Q14108,P51798,Q9NQ11,Q9NZJ4,Q8N0X7,Q9Y5Y5,Q9BVA1,P09471,O75787,O00429,O14936,Q7LG56,Q15043,O00754,P07437,Q06787,P41440,Q9H9S5,Q92581,Q6PJG6,Q5XKP0,Q8NHS3 37 +Onychomycosis 0.516518936341663 0.1588722595543631 0.8737695167442132 1.0 1.0 2 P16885 1 +Abnormality of hair pigmentation 0.3212763906552451 0.1585735991116909 0.8740048304269938 1.0 1.0 27 Q9Y2Q5,Q15477,Q86YV9,Q04656,P10644,Q05086,Q9UBM7 7 +Hyperventilation 0.3770989307616785 0.1583473818448618 0.8741830737637013 1.0 1.0 5 P11166 1 +Bilateral cleft palate 0.3992339976478208 0.1573626479886043 0.8749590492369614 1.0 1.0 4 O60716 1 +Pain in head and neck region 0.3563221193369593 0.1539359024084092 0.8776602754471416 1.0 1.0 8 P29992,Q15043 2 +Neoplasm of the adrenal gland 0.3348082909289013 0.1526107714961892 0.8787052300834377 1.0 1.0 15 P10644 1 +Spinal muscular atrophy 0.3346785511768849 0.1519912504767718 0.8791938365838541 1.0 1.0 15 Q13510,Q04656 2 +Anal atresia 0.3145950010356678 0.1505397171328127 0.8803388180093124 1.0 1.0 40 Q9H9B1,Q5SZK8,Q8TAA9,Q9H9S5,P53701 5 +Dimple chin 0.5103411227504635 0.1500772248335864 0.8807036884110908 1.0 1.0 2 Q69YQ0 1 +Autism 0.3168133851614236 0.1494710445703609 0.8811819557643525 1.0 1.0 51 Q9H9B1,P21964,P10644,Q06787,Q9H2C2,Q92581,Q05086,Q9UBM7 8 +Palmar telangiectasia 0.509535320977708 0.1489656303610683 0.8815807533126356 1.0 1.0 2 Q13043 1 +Median cleft palate 0.5095353209777046 0.1489656303610636 0.8815807533126394 1.0 1.0 2 Q8N3U4 1 +Abnormal pelvis bone ossification 0.5095353209776922 0.1489656303610467 0.8815807533126527 1.0 1.0 2 Q8NCM8 1 +Abnormality of malar bones 0.2989157364019579 0.147356630518597 0.8828505355913263 1.0 1.0 72 Q9H9B1,O00754,Q8WVQ1,O95831,P10644,Q9Y487,P98164 7 +Vaginal atresia 0.3932786337879831 0.1461830339491251 0.8837768986252765 1.0 1.0 4 Q15058,Q5SZK8 2 +Porencephalic cyst 0.3536179430946832 0.1452670677646498 0.884500014996602 1.0 1.0 8 Q6NUS6,Q9Y3Z3,P07942 3 +Abnormal peripheral nervous system physiology 0.3098493953644321 0.1450424437350413 0.8846773608355876 1.0 1.0 63 Q9NZJ4,P15289,O43681,Q6PIJ6,O95831,P51149,Q13614,O15269,Q9Y619,P07602,O95721,Q7LG56,Q99519 13 +Psychomotor retardation 0.3149123768564276 0.1447987573582812 0.8848697633702542 1.0 1.0 42 P16278,O95831,P04062,P98155,Q99519 5 +Abnormal globus pallidus morphology 0.3500033841645323 0.1437527403334886 0.8856957229004885 1.0 1.0 9 P02792 1 +Abnormality of the common coagulation pathway 0.3323222275240219 0.1407949012335682 0.888031971167677 1.0 1.0 15 Q15833,P10644,Q4KMQ2 3 +Abnormality of circulating enzyme level 0.3407540809527528 0.1375383282500662 0.8906052990345394 1.0 1.0 109 Q14126,O43505,P31483,Q08J23,O95831,Q13501,O14979,Q9BUK6,Q07021,P23786,P10253,P13473,Q14118,P22626,P50402,Q13049,Q9H9S5 17 +Sparse eyebrow 0.3116928390411042 0.1375186030793996 0.8906208893064911 1.0 1.0 38 Q14574,Q07954,Q08J23 3 +Abnormality of limb epiphysis morphology 0.3090973550607734 0.1362335933560362 0.8916366190688523 1.0 1.0 35 Q8WVQ1,P10644,Q7LGA3,O95831 4 +Multiple enchondromatosis 0.3640477915736401 0.1359994585137569 0.8918217090310894 1.0 1.0 6 P48735 1 +Dry skin 0.3106988375675487 0.1355554566543052 0.8921727207572161 1.0 1.0 37 Q2TAA5,Q04721,Q15477,Q08J23,Q04656,Q06136,P04066 7 +Hyperparathyroidism 0.3668008471530083 0.1352038941224264 0.892450668302416 1.0 1.0 5 P29992 1 +Abnormal platelet volume 0.3501969971015309 0.1344794143436205 0.8930234881933554 1.0 1.0 8 O75845 1 +Lobar holoprosencephaly 0.4982540961590032 0.134252984769619 0.8932025293084049 1.0 1.0 2 Q6NUS6 1 +True hermaphroditism 0.4982540961590032 0.134252984769619 0.8932025293084049 1.0 1.0 2 Q6NUS6 1 +Mixed demyelinating and axonal polyneuropathy 0.4868350349274487 0.1326417822452265 0.8944766869013034 1.0 1.0 3 P00403,P07196 2 +Thickened skin 0.3551577946140322 0.1313480502443533 0.8954999824155032 1.0 1.0 121 Q9P265,P04062,P06280,P50402,P16278,O95470,P53634,Q9NWM8,O15269,O95721,Q06136,Q9Y5Y5,Q14574,Q8WWQ0,Q04656,O75844,Q15800,P04066,Q99519,Q04721,Q14126,P31751,Q07954 23 +Chondrocalcinosis 0.3510457408781502 0.1303716390424833 0.8962724038262366 1.0 1.0 7 P29992,Q04656 2 +Postaxial polydactyly 0.3164278646740038 0.1296571463033681 0.8968376885784584 1.0 1.0 28 P17252,Q7Z4L5,O75845,P22694,O00459,P17612,Q13049,Q9UBM7 8 +Central hypothyroidism 0.3328716952956896 0.1282215275159741 0.8979736641925513 1.0 1.0 14 P16870,P35222,Q92560,O14654 4 +Congenital sensorineural hearing impairment 0.3480621559226984 0.1278503049749801 0.8982674390748333 1.0 1.0 8 Q16740 1 +Neoplasm of the peripheral nervous system 0.3224875465238002 0.12752417784539 0.8985255382473347 1.0 1.0 20 Q07954 1 +Genetic anticipation 0.4926134837496546 0.1274814816259651 0.8985593291136882 1.0 1.0 2 Q9UBB4 1 +Neonatal onset 0.3169719941485193 0.1271560009969315 0.8988169287443668 1.0 1.0 24 Q15904,O75787 2 +Auditory hallucinations 0.4817606801568459 0.1259092526687369 0.8998037583977962 1.0 1.0 3 Q9NWW5 1 +Female hypogonadism 0.3489679882538017 0.12445129570305 0.900957960894932 1.0 1.0 7 O75844 1 +Elevated circulating aspartate aminotransferase concentration 0.3287439478574014 0.1239976023357406 0.9013171734718464 1.0 1.0 15 Q15904,P38571 2 +Homocystinuria 0.378977171453695 0.1214512348751356 0.903333637624406 1.0 1.0 4 O14678 1 +Prominent supraorbital ridges 0.3333999817752758 0.1194139692003491 0.9049473946623272 1.0 1.0 13 Q9UPP1 1 +Abnormal hand bone ossification 0.3381446437047347 0.1183352246086416 0.905802048264822 1.0 1.0 11 Q8WVQ1,P22413,Q15643,Q96L58 4 +Gastrointestinal hemorrhage 0.3111825483081089 0.1183023158997274 0.9058281224646474 1.0 1.0 41 P17301,P01889,P21964,O00192,Q04656,Q6YHK3,Q02241 7 +Cutaneous syndactyly 0.3304983590310588 0.1177226852524926 0.9062873915330504 1.0 1.0 14 Q5SZK8 1 +Abnormal blood monovalent inorganic cation concentration 0.3205145233250323 0.1166125410901377 0.9071670991807832 1.0 1.0 20 Q13423 1 +Gonadal neoplasm 0.308158812333088 0.1162434429236172 0.9074596076280166 1.0 1.0 34 O75874,Q01844,Q13423,P10644,Q14145,P51809,P48735 7 +Leukoencephalopathy 0.3361482892871588 0.1148279213138322 0.9085815174261548 1.0 1.0 107 Q9H9P8,O00584,O75306,Q9NWW5,Q9H270,P07602,P17900,O75503,P15289,Q01105,P67870,Q9NQ11,O43676,O00429,Q7LG56,O96000,P07942,Q93009,Q9Y6M9,O95831,Q9H9S5 21 +Severe lactic acidosis 0.3738242407954804 0.1132706009817738 0.9098160242273204 1.0 1.0 4 Q70HW3,Q86YH6,P08559 3 +Breathing dysregulation 0.3735554958344507 0.1128545116210876 0.9101459003228788 1.0 1.0 4 O75380,Q10713,O15078 3 +Abnormal circulating gonadotropin concentration 0.3217930047243119 0.112350417482136 0.9105455674480808 1.0 1.0 18 P16870,P51809 2 +Biparietal narrowing 0.3332467081286094 0.1113108284018978 0.9113698689453044 1.0 1.0 12 O75845 1 +Short nose 0.3383038269970337 0.1107449238521311 0.911818620975332 1.0 1.0 109 P42892,Q9H9B1,Q15392,Q8WVQ1,Q8NCH0,Q9NX62,Q5KU26,P04062,P10644,O75844,P98164 11 +Orofacial dyskinesia 0.3400128239554937 0.1106266041941966 0.9119124498747762 1.0 1.0 9 P02792 1 +Vertical nystagmus 0.4762288477034525 0.1099384335842239 0.9124582016769818 1.0 1.0 2 P49959 1 +Leukodystrophy 0.3054026248024949 0.1097143302358205 0.9126359351437616 1.0 1.0 64 Q9NUM4,P15289,O43676,Q14118,P07602 5 +Mitochondrial myopathy 0.3096969262979476 0.1073454509234585 0.9145149282039068 1.0 1.0 32 O75380,Q9NPL8,Q9BUK6,O43676,O75306,Q9Y606,O96000,Q7LG56,Q9Y6M9 9 +Multiple rows of eyelashes 0.4656571484123896 0.1064670116365653 0.91521182751485 1.0 1.0 3 O60716 1 +Soft tissue sarcoma 0.308459824810754 0.1062177517431401 0.9154095867673756 1.0 1.0 39 Q07954,Q15392 2 +Exercise induced myalgia 0.3277499324452505 0.1057050333897314 0.915816386661486 1.0 1.0 14 Q8NCE2,P50570,P23786,Q7LG56,P43243,Q13049,P46020 7 +Dyskinesia 0.2974093684444595 0.1051006776719861 0.916295921579108 1.0 1.0 78 P02792,Q08J23,P09471,Q01105,O75306,O00592,P04062,Q9H2C2,O14936,P67870,P55011,P11166,Q9NQ11,O00571,Q15043,P35610 16 +Staring gaze 0.4700510341122759 0.1041126601835072 0.91707994408624 1.0 1.0 2 P42858 1 +Choking episodes 0.4700510341122759 0.1041126601835072 0.91707994408624 1.0 1.0 2 P42858 1 +Excessive wrinkled skin 0.3364490388926703 0.1039290290015706 0.9172256700325814 1.0 1.0 10 P22413,Q9Y487,P36543 3 +Prominent superficial blood vessels 0.3296458973889221 0.1038352604699455 0.917300083892445 1.0 1.0 13 O75844 1 +Thoracic scoliosis 0.3312981824015402 0.1036805582162458 0.917422855787288 1.0 1.0 12 O75844,Q96J02 2 +Elevated tissue non specific alkaline phosphatase 0.4614034358834101 0.1018090606355419 0.9189082336764274 1.0 1.0 3 P22413 1 +Progressive pes cavus 0.3403469063375528 0.1006971616548349 0.9197908645938048 1.0 1.0 7 Q12768,O00400,Q9NQ11 3 +Confetti like hypopigmented macules 0.4657534246575299 0.1003035748310945 0.9201033195027236 1.0 1.0 2 O00255 1 +Death in childhood 0.311860522688217 0.0991668748040699 0.9210057752603512 1.0 1.0 28 P07686,Q9H9S5,Q04656 3 +Impaired social interactions 0.3096713942448998 0.0974039788876895 0.9224055850606112 1.0 1.0 56 Q2TAA5,O43676,O75306,Q5KU26,O00592,Q06787,O96000,P11166,Q9Y6M9 9 +Congenital bilateral hip dislocation 0.4617244157937172 0.0969092279943926 0.9227984804236034 1.0 1.0 2 Q02809 1 +Uric acid nephrolithiasis 0.4545943041375504 0.0947564725064343 0.9245082611503264 1.0 1.0 3 P07741,P00492 2 +Poor speech 0.3266297168471408 0.0942886592743316 0.9248798583682452 1.0 1.0 101 Q9NUM4,Q08J23,Q13501,O00584,Q14118,P08236,Q15043,Q9H9S5,P98155 9 +Tibial torsion 0.4579640075207979 0.0938917260355447 0.9251951664697942 1.0 1.0 2 Q9Y5S9 1 +Red eye 0.3149579828533304 0.0938307226764922 0.9252436261740042 1.0 1.0 21 P02786 1 +Abnormality of the peripheral nervous system 0.3565373212094601 0.0935208324393341 0.9254898003280748 1.0 1.0 125 Q04446,Q13614,P04062,Q9H270,P07602,P06280,Q96EK5,P15289,P07686,O15269,O95721,P0DP25,Q9UBM7,Q9NZJ4,Q6PIJ6,P21964,Q04656,Q7LG56,Q99519,P42892,O95831,O00192,O00592,Q06787,Q9Y619,P41440,Q6PJG6 27 +Delayed ossification of carpal bones 0.3601668150082736 0.0934383705113626 0.9255553085812136 1.0 1.0 4 Q15643 1 +Ragged red muscle fibers 0.3180822250827393 0.0933443494696069 0.9256300000799018 1.0 1.0 18 Q9H2D1 1 +Posteriorly rotated ears 0.3613033567645335 0.0926738505322745 0.9261626718402808 1.0 1.0 129 O43505,P23786,P04062,Q14118,Q7LGA3,P11233,Q5SZK8,Q96J02,Q9UBM7,P98164,Q4J6C6,Q9Y5Y5,Q15392,Q08J23,Q8WVQ1,Q8NCH0,P42892,Q9Y619,Q13049,Q9H9S5 20 +Oligomenorrhea 0.3456449147431752 0.0921498863737057 0.9265789534349826 1.0 1.0 6 P31751 1 +Amegakaryocytic thrombocytopenia 0.4547408004297499 0.091418322442664 0.9271602035054642 1.0 1.0 2 Q06124 1 +Reduced factor xiii activity 0.4547408004297499 0.091418322442664 0.9271602035054642 1.0 1.0 2 Q06124 1 +Exercise induced muscle stiffness 0.453666398066073 0.0906166297834928 0.9277972176413996 1.0 1.0 2 P46020 1 +Abnormal libido 0.3443254690290143 0.090586878977485 0.9278208581222458 1.0 1.0 5 O00255,Q8WWQ0,P42858 3 +Multiple renal cysts 0.3178078308030924 0.0898462350912777 0.9284094064452382 1.0 1.0 17 Q04721,P21964 2 +Right ventricular dilatation 0.4492925095699551 0.0896021029670971 0.9286034132050642 1.0 1.0 3 P19022 1 +Ectopic anus 0.3175795796393461 0.08872706521194 0.9292988224322358 1.0 1.0 17 Q5SZK8 1 +Limb joint contracture 0.3424678456883344 0.087870853910352 0.9299793221839594 1.0 1.0 114 P42892,Q86XL3,Q15392,Q08J23,Q8WVQ1,P23786,Q8IZA0,O75844,Q14118,Q9Y619,Q7LGA3,P50402,O94766,Q9H9S5 14 +Psychotic mentation 0.355549583445308 0.0873322574108636 0.930407414258622 1.0 1.0 4 P00403,O00170,P48637 3 +Adrenocorticotropic hormone deficiency 0.444384739387415 0.0850875610992401 0.932191779247784 1.0 1.0 3 O00255,O00170 2 +Myelofibrosis 0.4442653773838321 0.0840722994892598 0.932998948458098 1.0 1.0 2 P27797 1 +Head banging 0.4430413756045026 0.0838941129660379 0.933140620233532 1.0 1.0 3 Q92993,Q96RL7 2 +Interstitial pneumonitis 0.4426537738383017 0.0830327240411495 0.933825519424506 1.0 1.0 2 P16885 1 +Abnormal circulating follicle stimulating hormone concentration 0.3282359541330275 0.0823277391822467 0.9343860966105436 1.0 1.0 11 P16870 1 +Asymmetry of the ears 0.4390112842557654 0.0804209945364345 0.935902429757674 1.0 1.0 3 Q9UHX1,Q9H2M9 2 +Agenesis of lateral incisor 0.4390112842557653 0.0804209945364345 0.935902429757674 1.0 1.0 3 Q12959,P54132 2 +Aplasia hypoplasia of the tongue 0.3394613659043586 0.0787077600467152 0.9372650730068972 1.0 1.0 6 P08754,Q9UBM7 2 +Atonic seizure 0.309038184325072 0.0773673551254124 0.9383313097549004 1.0 1.0 26 P09471,O75787,Q13510,O14936,P67870,P11166 6 +Abnormality of thyroid physiology 0.3147462380907833 0.0771187462840855 0.9385290800325564 1.0 1.0 93 P23458,P16870,Q15477,O95470,Q07021,P10644,Q96J02,O14654,P22413,Q9BUK6,P21964,O00429,Q8WWQ0,Q13423,Q7LG56,P04066,O00192,Q06787,Q9Y6N7 19 +Tall stature 0.2999952819205773 0.0751492865576706 0.9400959336559888 1.0 1.0 66 Q9H9B1,O00754,P17252,Q3ZCQ8,P61978,Q5H8A4,Q8NCH0,Q9NWM8,Q13423,P10644,Q7LGA3,P55011,P17612,Q13049 14 +Limited extraocular movements 0.3303115946059932 0.0747374063641719 0.9404236449115676 1.0 1.0 7 O75306 1 +Skin plaque 0.3350708934469867 0.0745919408796053 0.9405393865067752 1.0 1.0 5 Q06136 1 +Noncompaction cardiomyopathy 0.431757119828039 0.0745659024324563 0.9405601044846936 1.0 1.0 3 P21912,Q15233 2 +Ulcerative colitis 0.4306824288017099 0.0737408668302505 0.9412165802621107 1.0 1.0 3 Q13043,P16885 2 +Abnormality of bone mineral density 0.3965688564144884 0.072615647671989 0.942111974552538 1.0 1.0 161 Q13501,P04062,P07602,P06280,Q9Y487,P16278,P34059,O75718,P54802,Q32P28,Q13510,P10644,P51809,P51798,Q14108,Q86WC4,P51688,Q15392,Q8WVQ1,Q04656,O75844,Q15043,Q04721,O00754,O95831 25 +Abnormal central sensory function 0.3336196758423205 0.0722093193300179 0.9424353287837826 1.0 1.0 5 O75787 1 +Abnormality of facial soft tissue 0.3628980359726841 0.0713130529469355 0.9431486069301688 1.0 1.0 132 O00754,P02792,Q9Y5Y5,Q13501,Q9BUK6,O75787,Q13510,P10253,O00592,P04062,O75844,Q9NQ11,P51798,Q15043,Q9H9S5,Q99519 16 +Absent distal phalanges 0.4182111200644433 0.0699486589051897 0.9442345237396436 1.0 1.0 2 Q6NUK1 1 +Increased c peptide level 0.4139135106097253 0.0681224780674721 0.945688137008554 1.0 1.0 2 Q16836 1 +Speech articulation difficulties 0.3339215059932714 0.0672269713714541 0.9464010136405512 1.0 1.0 6 Q12959,P08754 2 +Profound sensorineural hearing impairment 0.3301075268817128 0.0665832529755045 0.9469134783455018 1.0 1.0 5 P60891,Q15046,P35241,P55011 4 +Abnormal mitochondria in muscle tissue 0.3062819773501506 0.0644670421731992 0.9485983490390536 1.0 1.0 23 O75380,Q9NPL8,O43676,O75306,O96000,Q96CU9,Q9Y6M9 7 +Increased megakaryocyte count 0.4172487909725865 0.0643114178653401 0.948722262134856 1.0 1.0 3 P27797,P04637 2 +Agenesis of corpus callosum 0.3251453904939723 0.064001744540532 0.9489688377152916 1.0 1.0 102 Q9H9B1,Q86XL3,O43505,Q15392,P23786,Q14118,Q7LGA3,Q9H9S5,Q86WC4,P98164,P53701 11 +Csf pleocytosis 0.3281324659837 0.0635063157598878 0.9493633301487914 1.0 1.0 5 Q15833 1 +Abnormal insulin level 0.3057892850606744 0.0623012746834576 0.9503229134001414 1.0 1.0 29 P16870,Q9HCM3,O75844 3 +Fulminant hepatic failure 0.4140247178935982 0.0622825480620587 0.9503378261213627 1.0 1.0 3 Q16836,Q96RP9 2 +Bladder neoplasm 0.3235634714116668 0.0601376786980635 0.9520459809927267 1.0 1.0 9 O14965,Q04656 2 +Bimanual synkinesia 0.4089089549159495 0.0592399738105162 0.9527609710360514 1.0 1.0 3 Q8WWQ0 1 +Segmental peripheral demyelination remyelination 0.330018812147267 0.0587945739110767 0.9531157303777418 1.0 1.0 4 P60891,P07196,P50570 3 +Abnormal pons morphology 0.3056828610272282 0.0586789057727289 0.9532078611365312 1.0 1.0 28 Q9NZJ4,Q9BVA1,Q9UNW1,Q14118,O14936,Q9H9S5 6 +Abnormality of bone marrow cell morphology 0.3019414531120749 0.057890818892747 0.9538355963208665 1.0 1.0 62 O00754,P04062,P10644,Q14108,Q86WC4 5 +Abnormality of circulating fibrinogen 0.322765825931242 0.0578239491782185 0.9538888614071914 1.0 1.0 9 P10644 1 +Impaired collagen induced platelet aggregation 0.3798012355627208 0.0576493579593156 0.9540279330526084 1.0 1.0 2 P27797 1 +Angioedema 0.3789954337899558 0.0574752763434914 0.9541666001643998 1.0 1.0 2 P16885 1 +Square face 0.3771152296535051 0.0570801394975463 0.9544813570104024 1.0 1.0 2 Q9UHX1 1 +Cerebellar vermis atrophy 0.316155145885389 0.0567576188214183 0.954738274764276 1.0 1.0 14 Q9NZJ4,Q9Y5Y5,Q15334,P07437 4 +Synostosis of metacarpals metatarsals 0.4035464803868802 0.0562754041564292 0.955122412416473 1.0 1.0 3 Q15233,P16435 2 +Thenar muscle atrophy 0.4016657710907991 0.0552883898888388 0.955908711545816 1.0 1.0 3 Q15120,O60568 2 +Mania 0.3157047180804528 0.0549159030712769 0.9562054621787626 1.0 1.0 14 P21964,Q7LG56,O00192 3 +Palpebral edema 0.3987103707683957 0.0537911165431507 0.9571015872454932 1.0 1.0 3 A6NHR9,O00170 2 +Suicidal ideation 0.3987103707683951 0.0537911165431502 0.9571015872454938 1.0 1.0 3 Q14203,P42858 2 +Hydroxyprolinuria 0.3553585817888844 0.0535033268624754 0.95733087999509 1.0 1.0 2 O00469 1 +Skin appendage neoplasm 0.3269133546737716 0.053469021105546 0.95735821290432 1.0 1.0 6 Q14145 1 +Central hypoventilation 0.3211403980634909 0.0526526084173378 0.958008699614187 1.0 1.0 7 Q14203,O43819,O75306,P06753,Q8N183,Q9BU61 6 +Cloverleaf skull 0.3432715551974266 0.0521677731312084 0.9583950112693792 1.0 1.0 2 P16435 1 +Adrenocortical adenoma 0.3416599516518989 0.0520179861828783 0.9585143619138192 1.0 1.0 2 O00255 1 +Multiple gastric polyps 0.3416599516518988 0.0520179861828783 0.9585143619138192 1.0 1.0 2 P20585 1 +Impaired use of nonverbal behaviors 0.320709105560038 0.0505537831074642 0.959681091437613 1.0 1.0 2 Q9GZY8 1 +Parathyroid carcinoma 0.3118452860596356 0.0501505831561924 0.9600023908911488 1.0 1.0 2 O00255 1 +Shortened qt interval 0.3118452860596356 0.0501505831561924 0.9600023908911488 1.0 1.0 2 O00255 1 +Recurrent pancreatitis 0.3118452860596305 0.0501505831561921 0.960002390891149 1.0 1.0 2 P00403 1 +Hypoplastic pelvis 0.3107708836959482 0.0501085578203213 0.9600358801525348 1.0 1.0 2 O75147 1 +Spondyloepimetaphyseal dysplasia 0.320137233547747 0.0488457991004072 0.9610421833076566 1.0 1.0 8 O95831,Q7RTS9 2 +Short sternum 0.3855454056958533 0.0478782876222077 0.961813243509584 1.0 1.0 3 P98175,Q6KC79 2 +Typical absence seizure 0.3136019109945279 0.0463795064880116 0.963007770386493 1.0 1.0 14 Q01105,P67870,Q13510,P11166 4 +Pectus excavatum 0.3144257492194511 0.0449761415958646 0.9641263259537824 1.0 1.0 95 O00754,O75718,Q08J23,Q9BUK6,Q8NCH0,Q04656,P04062,Q96J02,Q7LGA3,Q9Y487,P50402,Q92581 12 +Aplasia hypoplasia of the humerus 0.3174597092346843 0.042760196585964 0.9658926934725792 1.0 1.0 9 O00116,Q04656 2 +Cerebral hamartoma 0.3672756582482438 0.0415060803290725 0.966892445631315 1.0 1.0 3 Q6NUS6,Q2M1P5 2 +Csf lymphocytic pleiocytosis 0.3085192152647081 0.0411046974776399 0.9672124297247796 1.0 1.0 4 Q5TBB1,Q9Y3Z3,P55265 3 +Chilblains 0.3085192152647081 0.0411046974776399 0.9672124297247796 1.0 1.0 4 Q5TBB1,Q9Y3Z3,P55265 3 +Difficulty standing 0.3115591397849375 0.0401156065274762 0.9680009596072656 1.0 1.0 5 O43292,Q7RTS9,Q92734,Q8WVX9 4 +Abnormality of the auditory canal 0.302909525998922 0.0395101082931541 0.9684836945582084 1.0 1.0 27 P08754,Q5SZK8,P00533,Q9Y619,Q9H9S5 5 +Hypoplastic aortic arch 0.3551853842020339 0.038288695937508 0.9694575035138072 1.0 1.0 3 Q6W2J9,Q9UHX1 2 +Ileus 0.3015145809754098 0.0364601352503723 0.9709154650213732 1.0 1.0 4 Q01844 1 +Degeneration of the striatum 0.3086021505376293 0.0363899839858227 0.970971400512771 1.0 1.0 5 Q5TBB1,Q9Y3Z3,P42858,P55265 4 +Moyamoya phenomenon 0.3086021505376271 0.0363899839858196 0.9709714005127734 1.0 1.0 5 Q5TBB1,Q9Y3Z3,P55265,Q63HN8 4 +Difficulty climbing stairs 0.3060529556441687 0.0356911763353077 0.9715286063353714 1.0 1.0 19 Q14118 1 +Fibrosarcoma 0.3417517463729075 0.0354913408574045 0.9716879510216984 1.0 1.0 3 Q13126,P35222 2 +Gastrointestinal obstruction 0.305668043388242 0.0337778518667507 0.9730542975155204 1.0 1.0 19 P42892,Q5HYI8,Q04656,Q01844,P35222 5 +Falls 0.3117243176973996 0.0335439784793067 0.973240795793576 1.0 1.0 13 O75787,Q9NQ11 2 +Prolonged qtc interval 0.3164965072541537 0.0319741421712612 0.9744926719088234 1.0 1.0 3 P0DP25,P51608 2 +Decreased corneal reflex 0.3146157979580772 0.0317851835452696 0.9746433624850608 1.0 1.0 3 Q2TAA5,O95163 2 +Spastic gait 0.3005500772778151 0.0312846977300036 0.9750424938778492 1.0 1.0 30 Q9NZJ4,O75787,Q9Y619,Q15043,Q9ULH0 5 +Adenoma sebaceum 0.3037634408602071 0.0305780573393237 0.975606041672192 1.0 1.0 5 P52701,P21912,O00255,Q15437 4 +Angiofibromas 0.3037634408602071 0.0305780573393237 0.975606041672192 1.0 1.0 5 P52701,P21912,O00255,Q15437 4 +Lactose intolerance 0.2933906501880607 0.0301748612140914 0.9759275972447146 1.0 1.0 3 Q14566,P42345 2 +Spontaneous abortion 0.3033550228037313 0.0301034812771531 0.9759845243330448 1.0 1.0 5 Q8NCE2,P22413 2 +Pulmonary artery stenosis 0.3052520263605831 0.0300752767514507 0.9760070181037408 1.0 1.0 18 P51798 1 +Lacrimation abnormality 0.3040177700424641 0.0288372672388489 0.9769943782716496 1.0 1.0 20 Q07954 1 +Obstructive sleep apnea 0.3106457712718589 0.0276595634869512 0.9779336750167468 1.0 1.0 12 P51114 1 +Thin skin 0.3008195199657345 0.0265867025010089 0.978789379378804 1.0 1.0 26 P17252,O75844,P10644,Q06787,Q9Y619,P17612 6 +Abnormal magnesium concentration 0.3116429147620225 0.0264577311241695 0.9788922474625908 1.0 1.0 6 P61457,P53680,P05023,Q9NP81,P29992 5 +Wide nasal ridge 0.2762698199408722 0.0236403834492266 0.9811394598086428 1.0 1.0 4 P61978,Q15022,P27635 3 +Abnormal male reproductive system physiology 0.3024625788253347 0.0234930203676374 0.98125700588971 1.0 1.0 50 Q13423,P04062,O00592,P07686,P51809 5 +Optic disc coloboma 0.2970430107526842 0.0230800859661543 0.9815863905521808 1.0 1.0 5 P78318,Q6W2J9,Q10713,Q6KC79 4 +Aplasia hypoplasia of the breasts 0.3103737189624446 0.0216073945463719 0.9827611349148264 1.0 1.0 10 Q9Y619 1 +Distal amyotrophy 0.2936149068054921 0.0203254746619945 0.9837837341411484 1.0 1.0 67 P31483,Q13501,Q9BUK6,Q13510,Q04656,O15269 6 +Advanced eruption of teeth 0.3080768440133995 0.0188615226725885 0.9849515745354755 1.0 1.0 12 Q9H9B1,O75844 2 +Adrenal insufficiency 0.2961339692770062 0.0183942120472043 0.9853243697800678 1.0 1.0 33 Q6NUS6,Q9Y5Y5,O95470,O00255,Q13423,P51809,P38571,P82663,Q92560,O43716,P35222 11 +Severely reduced visual acuity 0.260682612201021 0.0183108818110494 0.9853908464927724 1.0 1.0 4 Q15051,O15078,P35222 3 +Undetectable light and dark adapted electroretinogram 0.2606826122010158 0.0183108818110477 0.9853908464927736 1.0 1.0 4 P55265,Q15555,P37198 3 +Enlargement of the costochondral junction 0.2598763773179173 0.0180802065473643 0.985574868258533 1.0 1.0 4 Q9Y3A5,Q7RTS9,Q5F1R6 3 +Abnormality of the costochondral junction 0.2598763773179175 0.0180802065473643 0.985574868258533 1.0 1.0 4 Q9Y3A5,Q7RTS9,Q5F1R6 3 +Recurrent acute respiratory tract infection 0.2580022654054483 0.0175596649962333 0.9859901343816128 1.0 1.0 4 Q03519 1 +Bladder diverticulum 0.3071312659091855 0.015105977849172 0.9879476318728444 1.0 1.0 9 Q15056,Q02809,Q04656,Q9NWM8 4 +Poor eye contact 0.2984962075043368 0.0122378775215945 0.9902358301919983 1.0 1.0 42 O75380,Q9NPL8,Q9UHX1,O43676,O75306,Q5KU26,Q06787,O96000,Q5XKP0,Q10471,Q9Y6M9 11 +Cranial nerve compression 0.3059558277511205 0.0117132054386467 0.990654427924287 1.0 1.0 12 P51798 1 +Retinal coloboma 0.3065683047103719 0.0106899395019643 0.9914708247607504 1.0 1.0 11 Q9NP72,O14936,Q9UHX1 3 +Type 1 muscle fiber atrophy 0.3029627891955803 0.0078119607125135 0.9937670205543438 1.0 1.0 8 P06753,P61978,P50402 3 +Lipodystrophy 0.2970815665684028 0.0060654638191745 0.9951604897387344 1.0 1.0 41 Q14126,O75844,Q9Y487,P50402,P04066 5 +Abnormal ureter morphology 0.2930852853876708 0.00483227041355 0.996144421048576 1.0 1.0 34 P23786,O75844,O14936,Q7LGA3,Q8TAA9 5 +Focal dystonia 0.2967669171968006 0.0038752428063574 0.9969080113344404 1.0 1.0 25 P02792,Q15043,Q9NQ11 3 +Simplified gyral pattern 0.2928516222368491 0.0031521187832352 0.9974849772538564 1.0 1.0 34 Q5KU26,Q86XL3,P98155 3 +Impaired t cell function 0.3032866379695094 0.0007485844822619 0.9994027160549308 1.0 1.0 11 P21964 1 +Muscle fiber atrophy 0.2961603535310985 0.0003441742999771 0.9997253886452446 1.0 1.0 25 P35637,P23786,P50402 3 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e698f54b3a0140916ea9a1147cb0dbbc8554296d --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal basophil count", "Abnormal basophil morphology", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal bowman capsule morphology", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcification of the carpal bones", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating aldosterone", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal coccyx morphology", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal endothelium morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal descemet membrane morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal energy expenditure", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal perifollicular morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pulse", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rapid eye movement sleep", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of cytokine secretion", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the 2nd finger", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of tumor necrosis factor secretion", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acromicria", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical adenoma", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Alzheimer disease", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal fissure", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior chamber synechiae", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior synechiae of the anterior chamber", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 2nd finger", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanges of the toes", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the 2nd finger", "Aplasia hypoplasia of the phalanges of the hallux", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar impression", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonate wasting renal tubular acidosis", "Bicarbonaturia", "Biconcave vertebral bodies", "Biconvex vertebral bodies", "Bicornuate uterus", "Bifid epiglottis", "Bifid nasal tip", "Bifid nose", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central opacification of the cornea", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cephalohematoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical c2 c3 vertebral fusion", "Cervical cord compression", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Chin with horizontal crease", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Choroideremia", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic myelogenous leukemia", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clinodactyly of the 2nd finger", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Common atrium", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical incisor", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crossed fused renal ectopia", "Crumpled long bones", "Cryptophthalmos", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gaba concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased nasal nitric oxide", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to polysaccharide vaccine", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased thyroid stimulating hormone level", "Decreased urine output", "Decreased vigilance", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Digital flexor tenosynovitis", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duodenal ulcer", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg myotonic discharges", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalomalacia", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid apraxia", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal clonic seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal eosinophilia", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked horizontal nystagmus", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Geographic atrophy", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucagonoma", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Halitosis", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Helicobacter pylori infection", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematochezia", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemophagocytosis", "Hemoptysis", "Hemorrhage of the eye", "Hemothorax", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent macular lesion", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hypereosinophilia", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hypergastrinemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermagnesiuria", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the fundus", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypoautofluorescent retinal lesion", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the bladder", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the primary teeth", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic iris stroma", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Imbalanced hemoglobin synthesis", "Immotile cilia", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired renal concentrating ability", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating interleukin 6", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hematocrit", "Increased hemoglobin", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intervertebral space", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urinary potassium", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Insulinoma", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Internally nucleated skeletal muscle fibers", "Interphalangeal joint erosions", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intervertebral space narrowing", "Intestinal atresia", "Intestinal bleeding", "Intestinal carcinoid", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal perforation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular iliac crest", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct aplasia", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large cafe au lait macules with irregular margins", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lenticonus", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low posterior hairline", "Low self esteem", "Low serum calcitriol", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphadenitis", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Moderately short stature", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple epiphyseal dysplasia", "Multiple exostoses", "Multiple gastric polyps", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thymus", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non convulsive status epilepticus without coma", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc drusen", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Palate fistula", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic calcification", "Pancreatic cysts", "Pancreatic endocrine tumor", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell adenoma", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid hyperplasia", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Peg shaped maxillary lateral incisors", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Percussion myotonia", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Perineal fistula", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Photosensitive tonic clonic seizure", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posterior uveitis", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent coccyx", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Punctate opacification of the cornea", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent spontaneous abortion", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Reflex seizure", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal angiomyolipoma", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal sodium wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocerebellar cyst", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rhizomelic arm shortening", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe platyspondyly", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Sex reversal", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short term memory impairment", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shortening of all phalanges of the toes", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Silver gray hair", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowed slurred speech", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small forehead", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue neoplasm", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spondylometaphyseal dysplasia", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Stapes ankylosis", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Status epilepticus without prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous lipoma", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Thinning of descemet membrane", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth abscess", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral cleft lip", "Unilateral cleft palate", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Wide pubic symphysis", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced primary teeth", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASS", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAR", "ADAT3", "ADCY3", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFF4", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP9", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ALG9", "AMPD2", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO10", "ANO6", "ANXA11", "AP1B1", "AP1S2", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APOL2", "APP", "APRT", "ARCN1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP6", "ARSA", "ARV1", "ARVCF", "ASAH1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATG7", "ATIC", "ATL3", "ATM", "ATP11C", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7A", "ATRX", "ATXN10", "AURKA", "B3GALT6", "B3GAT3", "B4GAT1", "BANF1", "BAP1", "BARD1", "BAZ1B", "BCAP31", "BCAT2", "BCKDHB", "BCKDK", "BCL10", "BCOR", "BCR", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BRIP1", "BUB1B", "BUB3", "BUD23", "C12orf57", "C19orf70", "C1QBP", "C21orf59", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CAPN1", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBL", "CBX2", "CC2D1A", "CCDC22", "CCDC47", "CCNK", "CCT5", "CD109", "CD2AP", "CD320", "CD3EAP", "CDC40", "CDC42", "CDC45", "CDC6", "CDC73", "CDH2", "CDK13", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDKN2A", "CELF2", "CENPF", "CEP250", "CEP290", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHEK2", "CHM", "CHMP2B", "CHORDC1", "CHST14", "CHUK", "CISD2", "CIT", "CIZ1", "CLASP1", "CLCC1", "CLCN7", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "CNP", "COA3", "COA7", "COASY", "COCH", "COG4", "COG7", "COG8", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ5", "COQ8A", "COX15", "COX2", "COX4I1", "COX5A", "CPE", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRAT", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSB", "CTSC", "CTSF", "CTU2", "CUL3", "CUL4B", "CWC27", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "DAG1", "DARS", "DARS2", "DAXX", "DBT", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIP2B", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DMD", "DMXL2", "DNA2", "DNAAF5", "DNAJB11", "DNAJB6", "DNAJC13", "DNAJC21", "DNAJC3", "DNM1", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DOCK6", "DOCK7", "DPF2", "DPH1", "DPM1", "DPP9", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EHHADH", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "ELP4", "EMC1", "EMD", "EMG1", "ENPP1", "EPB41", "EPHA2", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERLIN1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "FAH", "FAM50A", "FANCA", "FANCD2", "FANCI", "FAR1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBXO38", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXC1", "FOXRED1", "FREM2", "FSCN1", "FTL", "FTO", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALE", "GALK1", "GALNS", "GALNT2", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GCLC", "GDAP1", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLE1", "GLMN", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GNA11", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNPAT", "GNS", "GOSR2", "GOT2", "GPAA1", "GPD2", "GPHN", "GPI", "GPKOW", "GPT2", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HCFC1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBCH", "HIKESHI", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP2", "IGF2R", "IGHMBP2", "IMPAD1", "IMPDH1", "INF2", "INTS1", "INTS8", "IQCB1", "IRF2BPL", "IRS4", "ISCA2", "ISCU", "ITCH", "ITGA2", "ITM2B", "ITPA", "IVD", "JAGN1", "JAK1", "JUP", "KANK2", "KARS", "KAT5", "KDM1A", "KDM3B", "KDM5B", "KDSR", "KEAP1", "KIAA0319L", "KIAA1549", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF7", "KIFBP", "KIRREL1", "KLC2", "KMT2A", "L2HGDH", "LAMB1", "LAMC1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDLR", "LEMD2", "LEMD3", "LETM1", "LIPA", "LLGL1", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRIG2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC8A", "LSS", "LZTFL1", "MACF1", "MAGED2", "MAGT1", "MAN2B1", "MANBA", "MAP1B", "MAP2K1", "MAP3K7", "MAPK1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MED12", "MED17", "MED23", "MED25", "MED27", "MEN1", "MESD", "MFF", "MFN2", "MFSD8", "MGAT2", "MIA3", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MMADHC", "MOCOS", "MOCS1", "MOGS", "MORC2", "MPDU1", "MPG", "MPI", "MPV17", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTMR14", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MVD", "MVK", "MYH14", "MYH9", "MYO5A", "MYO6", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFL", "NEK9", "NELFA", "NEMF", "NEPRO", "NEU1", "NF1", "NF2", "NFKBIL1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NID1", "NIPBL", "NNT", "NONO", "NOP10", "NOP56", "NOTCH2", "NPC1", "NPC2", "NPM1", "NR2F1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "OAT", "OBSL1", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "ORC1", "OSBPL2", "OSTM1", "OTULIN", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PALLD", "PANX1", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDHA1", "PDHB", "PDHX", "PDK3", "PDP1", "PDSS1", "PDSS2", "PDXK", "PEPD", "PEX14", "PEX16", "PEX19", "PEX3", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4KA", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGO", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PISD", "PITRM1", "PKN1", "PKP2", "PLAA", "PLCG2", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNP", "PNPLA6", "PNPT1", "PODXL", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPOX", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKACA", "PRKACB", "PRKAR1A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QRICH1", "QRSL1", "RAB18", "RAB33B", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RABL3", "RAC1", "RAD21", "RAD50", "RAD54B", "RALA", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RB1CC1", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RBPJ", "RDH11", "RDX", "RELA", "REPS1", "RFC1", "RFC2", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF213", "ROBO1", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS26", "RPS28", "RPS29", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RREB1", "RRM2B", "RRP7A", "RTN2", "RTN4IP1", "SACS", "SALL2", "SAMHD1", "SARS", "SARS2", "SBDS", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SCYL1", "SCYL2", "SDHA", "SDHB", 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0.0107002906541049 6.849514563106796 16.725728155339805 0.1092386662992923 0.5937456832302471 4.017760903410304 2.3953875993966403 0.9524162344483764 0.3203538229624096 0.2283839235532806 1.0 1.0 0.7755841231055027 0.0739124968095968 +Calcium signaling pathway 12 24 2.547867938233862 0.0108383491888259 5.735436893203883 16.946601941747574 1.0005800740695592 0.3113014190776675 2.984654368989517 2.3866666657890168 1.2450167285670062 0.3187454651207294 0.0080863990245203 1.0 1.0 0.0715305134437747 0.0370324845913321 +Dilated cardiomyopathy 9 15 2.179476249060168 0.0292963071906626 3.0097087378640777 8.393203883495145 0.4535126033788805 0.4859001261794073 1.6428435307790814 1.6853890758730747 0.9621453761461582 0.3132641846990659 0.1157633766244994 1.0 1.0 0.2871762535363917 0.0048404074215544 +Galactose metabolism 2 14 2.1775071876692262 0.0294427461125232 4.58252427184466 13.216019417475728 -0.1782313827276002 0.4435757909481123 2.9055496675792862 0.5161805957123455 1.1764125997304256 0.3166437961140673 0.0118457633601407 8.597904339497348e-05 0.0006327439593496 0.0086586519898169 0.053660443290246 +Melanogenesis 10 15 2.1664744833605147 0.0302749476686006 4.114077669902913 11.631067961165048 -0.2380706557454032 0.5969767566086969 2.790256256072175 2.1417726587093395 0.7803605998169906 0.2975276394790953 0.45028787057676 1.0 1.0 0.7462567628712866 0.0178329562909439 +Natural killer cell mediated cytotoxicity 3 18 2.1656966311487675 0.0303343766474426 4.859223300970874 15.269417475728156 0.0010910938828692 0.6578096713542636 2.9270395558972484 2.707009357328761 0.724843022952491 0.2863674189596557 0.1032494734077335 0.2778293030066073 0.1323300889211223 0.0747731306641884 0.2148519458953993 +Jak stat signaling pathway 5 11 2.155324655210473 0.031136437751817 2.5388349514563107 7.325242718446602 0.1247408981464117 0.5305016303730072 1.7532069372986143 1.6446570419841182 0.9424863908946578 0.315817052482574 0.3939740757359061 0.2183837422916212 0.3837329617110586 0.705985725150242 0.0931745181672324 +Ecm receptor interaction 6 9 2.1456467989331007 0.0319011686906067 1.6650485436893203 4.555825242718447 0.2096433457400827 0.4422389760138975 1.377503633308977 1.8273249716413784 1.143329174769281 0.3102717144634864 0.1157633766244994 1.0 0.3467918934582977 0.0893115916137597 0.0048404074215544 +Type i diabetes mellitus 3 6 2.0876928496444647 0.0368255502634085 1.7597087378640777 4.854368932038835 0.2295754227924032 0.537404328385132 1.0159064595639915 0.605921700063298 0.9114211067852314 0.3048453574503886 0.0005664524138943 1.0 0.1349531130589082 0.000366006536683 0.0048470794580564 +Axon guidance 10 26 2.0655551912370447 0.0388704991197799 8.555825242718447 23.703883495145632 -0.5599721042699952 0.5024934418739405 4.39376102780521 3.606181917937803 0.90571396816964 0.3154927590117977 0.1074717588223361 1.0 1.0 0.0740089890485984 0.0051672295609291 +Viral myocarditis 4 14 2.0424157135613745 0.0411103123566478 4.031553398058253 11.228155339805824 0.0319814940949768 0.5543700591424958 2.250452924114055 1.5125313108034515 0.956572263574295 0.3192370987906132 0.0033852941785498 1.0 0.3076603852203092 0.0128293519549119 0.0351185939844577 +Glycosaminoglycan biosynthesis chondroitin sulfate 3 5 2.0070768606492164 0.0447414796371941 0.7474489795918368 2.125 1.0665503853393523 0.2409358913812838 0.8299210820909171 1.0581016405018249 1.5388974782751526 0.2572296229318129 0.008459922663953 1.0 0.1432798584585485 0.0061570039439817 0.0062187451165004 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..47c9da5d0bb53b121acf9d0f343a4815c84bd8f2 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 181, + "title": "Average number of proteins per term", + "value": 18.823204419889503 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d5b426dc3dfbd2e1dbddabea29c43c450dde7899 --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8a6846181ae85fb8ab897a562658c200033df233 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,92 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Lysosome 0.9116045745937384 5.0534110493099895 4.339884836168594e-07 7.854884745787609e-05 7.855191553483254e-05 60 Q93050,O14773,Q9UMR5,P07711,Q99523,P07858,Q15904,P04062,O00115,P13473,P07602,P06280,P15586,P17900,Q9UBX1,O75503,P11117,Q99538,P16278,P34059,P50897,P15289,P54802,P06865,P53634,P61916,Q13510,O00462,P10253,P07686,P38571,P08236,P11717,P10619,Q14108,P51688,P11279,Q8NCC3,P04066,Q99519,O00754,P20645,O15118,Q8NHS3 44 +Antigen processing and presentation 0.8023179790847105 2.997336776723518 0.0027234965926219 0.3895905895809554 0.1136767470188043 20 Q99538,P07711,P04439,P07858,P10321 5 +Cell adhesion molecules cams 0.8452556760471338 2.9938437211159523 0.0027548701179778 0.3930565090476028 0.1136767470188043 16 P06756,Q92896,P13591,P04439,Q92859,P01889,Q9BY67,P10321,Q16625,P10586,Q92692,Q5ZPR3,Q9Y624,P05556 14 +Sphingolipid metabolism 0.8629111675650039 2.8798637561207263 0.0039784705527226 0.5139964912041262 0.1136767470188043 14 P16278,Q9NRA0,P15289,Q13510,P04062,O15269,P06280,Q16739,Q06136,Q99519 10 +Other glycan degradation 0.9631324004305756 2.8597153860000093 0.0042402136867012 0.5365748651452579 0.1136767470188043 9 O00754,P16278,P06865,O00462,Q9BTY2,P07686,P04066,Q99519 8 +Glycosaminoglycan degradation 0.9488835082055416 2.718066688853289 0.006566460162682 0.6965227626008441 0.1320588099383831 8 P16278,P34059,P54802,P06865,P07686,P15586,P08236 7 +Snare interactions in vesicular transport 0.7618729115767856 2.675449123542354 0.0074629199335625 0.7422729345551718 0.1350788507974815 18 O43752,Q9P2W9,Q86Y82,O00161,O95249,Q9UNK0,O15400,O95721,P51809,Q5SQN1,Q9NZ43,Q9UEU0 12 +Gap junction 0.7290202223516448 2.5523371890689943 0.0107002906541049 0.8573254378725148 0.1509031694751925 19 Q9BVA1,P62993,P08754,P17252,P22694,P07437,P00533,P04899,O60266,P17612,P63096,P29992 12 +Calcium signaling pathway 0.6823225847609797 2.547867938233862 0.0108383491888259 0.8608843484517806 0.1509031694751925 24 P21796,P17252,Q9NRA0,P45880,Q9Y277,P22694,P00533,Q93100,O60266,P17612,P0DP25,P29992 12 +Glycosphingolipid biosynthesis ganglio series 0.9641098408840652 2.227315644332464 0.0259261856944501 0.9913875205100398 0.2510483275217315 4 P06865,P16278 2 +Dilated cardiomyopathy 0.7014620680607057 2.179476249060168 0.0292963071906626 0.9954007247092436 0.2510483275217315 15 P17301,P06756,P17252,P22694,Q14118,O60266,P50402,P17612,P05556 9 +Galactose metabolism 0.7170051692981788 2.1775071876692262 0.0294427461125232 0.995524619868284 0.2510483275217315 14 P16278,P06280 2 +Melanogenesis 0.6989588889382963 2.1664744833605147 0.0302749476686006 0.9961682302061428 0.2510483275217315 15 O14641,P17252,P08754,P09471,P22694,P04899,O60266,P17612,P63096,P0DP25 10 +Natural killer cell mediated cytotoxicity 0.6672736601306323 2.1656966311487675 0.0303343766474426 0.996210500415484 0.2510483275217315 18 P10321,P15260,P04439 3 +Jak stat signaling pathway 0.7603217952247995 2.1553246552104732 0.031136437751817 0.9967376184534352 0.2510483275217315 11 P15260,P31751,P23458,Q92783,O00459 5 +Ecm receptor interaction 0.7926421013428125 2.1456467989331007 0.0319011686906067 0.99717209414197 0.2510483275217315 9 P17301,P05556,P06756,Q08722,Q14118,Q7L0J3 6 +Type i diabetes mellitus 0.8514046292801298 2.0876928496444647 0.0368255502634085 0.99887643919869 0.2777260249032058 6 P10321,P04439,P01889 3 +Axon guidance 0.5956771992136941 2.0655551912370447 0.0388704991197799 0.99923523977972 0.2814224136272065 26 Q9Y6N7,O15031,P29317,O94813,Q15375,P04899,P63096,O14786,P51805,P05556 10 +Viral myocarditis 0.6904053526108496 2.0424157135613745 0.0411103123566478 0.99949866815088 0.2861910206366639 14 P10321,Q14118,P04439,P01889 4 +Glycosaminoglycan biosynthesis chondroitin sulfate 0.8565112403821928 2.0070768606492164 0.0447414796371941 0.999747717848076 0.2999336227530419 5 Q9P2E5,Q8N6G5,Q8NCH0 3 +Graft versus host disease 0.8815361664468938 1.9057678837934375 0.0566803274791096 0.9999741024087766 0.3274648777091234 4 P10321,P04439 2 +Autoimmune thyroid disease 0.8815361664468938 1.9057678837934375 0.0566803274791096 0.9999741024087766 0.3274648777091234 4 P10321,P04439 2 +Allograft rejection 0.8815361664468938 1.9057678837934375 0.0566803274791096 0.9999741024087766 0.3274648777091234 4 P10321,P04439 2 +O glycan biosynthesis 0.8020838997753873 1.7864707364386685 0.074023071304984 0.9999990991965044 0.3337341468767067 5 Q86SF2,Q10472,O43505 3 +Porphyrin and chlorophyll metabolism 0.6384155165544797 1.7718927270594278 0.0764123659417514 0.9999994356639164 0.3337341468767067 14 P22830,P08236,P30519,P53701 4 +Hedgehog signaling pathway 0.7979022963803416 1.7693387779397158 0.0768373557851322 0.9999994807718126 0.3337341468767067 5 P98164,P17612,P22694 3 +Olfactory transduction 0.7719756945620594 1.7597173188932382 0.0784557478504632 0.999999622052708 0.3337341468767067 6 P0DP25,O60266,P17612,P22694 4 +Hypertrophic cardiomyopathy hcm 0.6351939954632444 1.754850354768684 0.079284907821538 0.999999678876243 0.3337341468767067 14 P17301,P06756,P50402,Q14118 4 +Glycosphingolipid biosynthesis globo series 0.9873723804406233 1.72336321131586 0.0848228633216057 0.9999998922457776 0.3373130239342199 3 P06865,P06280 2 +Notch signaling pathway 0.6802258840093455 1.7047635613332093 0.0882385300124823 0.9999999452349336 0.3373130239342199 10 Q04721,Q92542,P56545 3 +Glycosphingolipid biosynthesis lacto and neolacto series 0.9648133225893092 1.673138900369037 0.0942999551079206 0.9999999836252584 0.3373130239342199 2 O60512 1 +Glycosaminoglycan biosynthesis keratan sulfate 0.9648133225893092 1.673138900369037 0.0942999551079206 0.9999999836252584 0.3373130239342199 2 O60512 1 +Starch and sucrose metabolism 0.5868238965054646 1.669370373953086 0.0950440012190343 0.999999985888576 0.3373130239342199 17 P08236,P10253 2 +Renin angiotensin system 0.7639830437130075 1.629497598042088 0.103207722948645 0.9999999972633038 0.3459369972908286 5 Q9UIQ6 1 +Steroid biosynthesis 0.5946822864219277 1.5378567591550147 0.1240836419598796 0.9999999999614756 0.4010560570488967 14 Q15392,O75845,P56937,Q15800,Q16850,P38571,Q9UBM7 7 +Long term depression 0.5920261306136728 1.5234619204200768 0.1276431806518796 0.999999999981565 0.4053230824208809 14 P08754,P09471,Q14344,P04899,P63096,P29992 6 +Hematopoietic cell lineage 0.9229116304055944 1.5017001077604786 0.1331745760633704 0.9999999999941706 0.4155965218529319 2 P02786 1 +Endocytosis 0.4385961986466922 1.475360927460655 0.140115534112611 0.9999999999986396 0.4298459605827558 64 P01130,P04439,P01889,P10321,Q9BRG1,Q96J02,P00533,P02786,Q9Y3E7,Q92783,Q9H223,P46934 12 +Gnrh signaling pathway 0.5498918041504017 1.4233583130926395 0.1546323105653244 0.9999999999999376 0.4644542288477087 16 P62993,P22694,P00533,O60266,P17612,P0DP25,P29992 7 +Leishmania infection 0.6058688517728246 1.4094100708715558 0.1587139478714889 0.999999999999974 0.4644542288477087 11 P23458,P15260 2 +Amino sugar and nucleotide sugar metabolism 0.4926495228867438 1.3911382752024843 0.1641835002600469 0.999999999999992 0.4644542288477087 27 P06865,P07686 2 +Taurine and hypotaurine metabolism 0.8955143701316202 1.38966284478009 0.1646312824411957 0.9999999999999928 0.4644542288477087 2 Q9UJ14 1 +Progesterone mediated oocyte maturation 0.4605171753894123 1.2797254810165464 0.2006416997878097 1.0 0.491888433308402 32 P08754,Q99640,P31751,P22694,P14635,O00459,P04899,O60266,P17612,P63096 10 +Leukocyte transendothelial migration 0.4768131735496183 1.2784138068010242 0.2011035583691809 1.0 0.491888433308402 27 P08754,Q16625,O00459,P04899,P63096,O60716,Q9Y624,P05556 8 +Aldosterone regulated sodium reabsorption 0.5988243220712781 1.2553732488401954 0.2093432957861687 1.0 0.4953672605818016 9 O00459,P05026,O14654 3 +Dorso ventral axis formation 0.6531127218734266 1.251543239391892 0.2107363484243023 1.0 0.4953672605818016 6 Q04721,P00533 2 +Vibrio cholerae infection 0.4739642712056054 1.2054597124204995 0.2280258818135367 1.0 0.5173955522578255 24 Q93050,Q15904,P22694,P24390,O60266 5 +Small cell lung cancer 0.5092858601812051 1.1844472312581735 0.23623607309294 1.0 0.5173955522578255 16 P17301,P06756,P31751,O00459,P05556 5 +Taste transduction 0.8358409457281011 1.1509010016297372 0.2497729656874634 1.0 0.5173955522578255 3 P17612,P22694 2 +Arrhythmogenic right ventricular cardiomyopathy arvc 0.4921453505499642 1.1333233846465225 0.2570784750138106 1.0 0.5173955522578255 18 P17301,P06756,Q14118,P50402,P05556 5 +Steroid hormone biosynthesis 0.8280494357872088 1.121724504823452 0.2619795941377294 1.0 0.5210802916365826 3 P21964,P56937 2 +Prion diseases 0.5605442204940627 1.0722263898984603 0.2836183599284345 1.0 0.5461162036919857 9 P13591,P17612,P22694 3 +Epithelial cell signaling in helicobacter pylori infection 0.450567078215613 1.056615384484224 0.2906871563355424 1.0 0.5480664093409706 25 Q93050,P00533,Q15904,Q9Y624 4 +Cytokine cytokine receptor interaction 0.6689415294269638 1.0483539630662104 0.2944755557683884 1.0 0.5494853154028693 4 P15260 1 +Abc transporters 0.5382932662962332 1.0139017142767068 0.3106296533057051 1.0 0.5624257139071184 10 P08183,Q03519,P33527,O14678 4 +Pancreatic cancer 0.467941611871799 1.0101271239926668 0.3124343885685046 1.0 0.5624257139071184 19 P23458,P00533,P31751,P11233 4 +Cardiac muscle contraction 0.4517716312833861 0.9353418005096554 0.3496121797749343 1.0 0.5887611372105338 20 P08574,P00403,P06753,O14949,Q92581,P05026,P16615 7 +Glycerophospholipid metabolism 0.4512659552663145 0.9320610265225608 0.3513049879488268 1.0 0.5887611372105338 20 Q9HCL2,Q8NCC3,P35790 3 +Vascular smooth muscle contraction 0.4524741392624327 0.9119089565582464 0.3618166462812007 1.0 0.6008147979531865 19 P22694,Q14344,O60266,P17612,P0DP25,P29992 6 +Chemokine signaling pathway 0.4142922285835088 0.8757255353716483 0.381179259973319 1.0 0.6206531014442099 30 P62993,P08754,P17252,P31751,P22694,O00459,P04899,O60266,P17612,P63096 10 +Glioma 0.445719728600574 0.8689642912708494 0.3848666624705599 1.0 0.6206531014442099 19 P17252,P62993,P31751,P00533,O00459,P0DP25 6 +Pathways in cancer 0.3689438395340083 0.8456166599967226 0.3977666285498804 1.0 0.6206531014442099 68 P17301,P05556,P06756,O14641,P11233,P62993,P17252,P31751,P42345,P23458,P00533,O00459,P46108,P07942,P11166,Q13772,Q13309,P56545 18 +Non small cell lung cancer 0.4472578293402131 0.8138167403124227 0.4157499435188896 1.0 0.6367628693020283 16 P00533,O00459,P31751,P62993 4 +Tight junction 0.3881495871814646 0.7738596225080434 0.4390138094796854 1.0 0.6513237665231397 41 Q16625,P31751,O14936,P67870,P04899,P63096,P07947,Q9Y624 8 +Erbb signaling pathway 0.4327153423019665 0.7638480634651309 0.4449577907335413 1.0 0.6547752855509836 18 P62993,P17252,P31751,P00533,O00459,P46108 6 +Glycosaminoglycan biosynthesis heparan sulfate 0.5391379877578494 0.6941864944049979 0.4875652611805838 1.0 0.6948764745959503 5 Q7LGA3 1 +Apoptosis 0.4036199180943544 0.674410857232502 0.5000501420051773 1.0 0.7023404378107267 22 O95831,P31751,P22694,P10644,O00459,P17612 6 +Endometrial cancer 0.4379193742817436 0.6675147231779446 0.5044434083723452 1.0 0.7023404378107267 14 P62993,P31751,P00533,O00459,P35222 5 +Riboflavin metabolism 0.4889451908689784 0.6478600022551015 0.5170755026469005 1.0 0.7090744565665337 7 P11117,Q13614 2 +Alzheimers disease 0.3615194842852046 0.6128999365476622 0.5399425052311533 1.0 0.7348089732845018 58 Q07954,P08574,Q92542,O43676,P51970,O75306,P0DP25,O00213,O96000,P05067,Q9Y6M9 11 +Wnt signaling pathway 0.374214851176143 0.5543800018637544 0.5793188093604187 1.0 0.7767163295869317 29 O14641,P22694,P67870,P17612,Q8TAA9,Q16537,P56545 7 +Prostate cancer 0.3939188266872725 0.5246202810983842 0.5998471851147875 1.0 0.7884284106876569 18 P62993,P31751,P42345,P00533,O00459 5 +Adherens junction 0.3682169505824643 0.5227873930597738 0.6011222136734622 1.0 0.7884284106876569 30 Q9Y6W5,Q9UQB8,P10586,P00533,P67870,P07947,Q92692 7 +Glycerolipid metabolism 0.3762185819558542 0.3366015267352372 0.7364173051350662 1.0 0.9256356404822708 14 P06280 1 +Neurotrophin signaling pathway 0.3347060402824529 0.3076045761229934 0.7583832377036175 1.0 0.9401874385229778 33 Q99523,O14654,P62993,P31751,O00459,P0DP25,Q9ULH0 7 +Tyrosine metabolism 0.3852713793207143 0.2909579314874714 0.7710834939938565 1.0 0.9475322502894946 10 P14174 1 +Parkinsons disease 0.3319162909812082 0.2861310489370572 0.7747777516179293 1.0 0.9475322502894946 51 P21796,P45880,O43676,P51970,O96000,Q9Y277,Q9Y6M9 7 +Acute myeloid leukemia 0.3706316212745631 0.2705951359518008 0.7867024372563247 1.0 0.9556586653919112 12 O00459,P31751,P62993 3 +Melanoma 0.3609197827555049 0.2413831647607618 0.8092581596170874 1.0 0.9667876912915218 13 P00533,P31751 2 +Vegf signaling pathway 0.3527101872695886 0.2409079792362 0.8096264377139799 1.0 0.9667876912915218 15 O00459,P31751,Q9NRA0 3 +Pathogenic escherichia coli infection 0.3251393150235563 0.1788034246238963 0.8580920561596159 1.0 1.0 23 Q9BVA1,Q9BUF5,P17252,Q16625,P07437,P35222,P05556 7 +Regulation of autophagy 0.3521406836369946 0.1405839362352246 0.888198639220116 1.0 1.0 8 Q6PHR2 1 +N glycan biosynthesis 0.3242958961003072 0.1304317246782485 0.8962248683093628 1.0 1.0 19 P33908,Q2TAA5,Q16706,Q86YN1,O60512,Q9Y673 6 +Nitrogen metabolism 0.4838796346050417 0.1286848293203381 0.8976070400399143 1.0 1.0 3 P00367,O94925 2 +Fc epsilon ri signaling pathway 0.335431474028723 0.1199541345280319 0.9045194808705072 1.0 1.0 12 O00459,P31751,P62993 3 +Vasopressin regulated water reabsorption 0.3203285627943836 0.1091913277706932 0.9130507386182825 1.0 1.0 19 O43237,O60266,P17612,P22694 4 +Primary bile acid biosynthesis 0.4716626376577906 0.1055921782036566 0.91590593094498 1.0 1.0 2 P51659 1 +Chronic myeloid leukemia 0.3100318909955287 0.0753044910870707 0.9399724482602982 1.0 1.0 22 O00459,P31751,P62993,P56545 4 +Neuroactive ligand receptor interaction 0.3373623421971543 0.0516474931449032 0.9588095757549332 1.0 1.0 2 P30536 1 +Insulin signaling pathway 0.299958274961903 0.0237808846846015 0.9810273875498688 1.0 1.0 42 P62993,O14654,P17252,P31751,P22694,O75955,P10644,P10586,O00459,Q93100,P17612,P41440,P0DP25,Q14254 14 +Basal cell carcinoma 0.2860881137526859 0.0122366291577674 0.9902368261676456 1.0 1.0 5 O14641 1 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ee4664b11187ac8c280ab9cdb553e0a4c6023f13 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Taurine and hypotaurine metabolism", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACE2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAR", "ADCY3", "ADH5", "ADI1", "ADK", "ADO", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALG9", "ALYREF", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEX1", "APIP", "APP", "APRT", "AQR", "ARAF", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARG2", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AURKA", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BAIAP2", "BCAS2", "BCAT1", "BCAT2", "BCKDHB", "BCL10", "BCR", "BET1", "BIRC6", "BLM", "BLVRA", "BNIP1", "BPNT1", "BRCA1", "BUB1B", "BUB3", "BUD23", "BUD31", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CAPN2", "CARS", "CARS2", "CASK", "CASP8", "CBL", "CBR1", "CCDC6", "CCNB1", "CD276", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK7", "CDKN2A", "CDS2", "CETN2", "CFL1", "CFL2", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHMP2B", "CHMP3", "CHMP5", "CHORDC1", "CHPF2", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT10", "CNOT2", "CNOT9", "COASY", "COMT", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPE", "CPOX", "CPT1A", "CPT2", "CRAT", "CRK", "CRKL", "CRNKL1", "CROT", "CS", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CXADR", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DARS", "DARS2", "DAXX", "DBI", "DBT", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH2", "DIAPH3", "DIS3", "DLAT", "DLD", "DLG1", "DLST", "DMD", "DNA2", "DNASE2", "DNM1", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOLPP1", "DPM1", "DPYSL2", "DPYSL5", "DSG2", "DSP", "DTX3L", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFTUD2", "EGFR", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "EMD", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "EPB41", "EPB41L2", "EPB41L3", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERO1A", "ESPL1", "EXO1", "EXOC3", "EXOC4", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAH", "FAR1", "FARS2", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALE", "GALK1", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GBE1", "GCAT", "GCDH", "GCLC", "GCLM", "GFPT1", "GGCT", "GGH", "GGPS1", "GGT7", "GIT1", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPI", "GPT2", "GRB2", "GRHPR", "GSK3A", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTSE1", "GUSB", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HDAC1", "HDAC2", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGB1", "HMGCL", "HMGCS1", "HMMR", 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1.9886993890271983e-09 4.0511134725393265e-10 +Glycosphingolipid metabolism 11 17 3.4436548067496164 0.0005739079322906 7.514563106796117 15.521844660194176 0.6340330218232789 0.1371235236408302 2.3948329397108954 1.2175929202976112 2.2116324239586063 0.2290247571497847 2.609048245106991e-11 1.7086834647982223e-10 3.245872885260211e-13 6.74629942432968e-12 2.0478141365152117e-08 +Extracellular matrix organization 16 38 3.3743292768282127 0.0007399579851954 7.808252427184466 28.75728155339806 0.0816457709205555 0.5705124899153677 3.3832296074989077 4.083392886365088 0.966248903682439 0.3167495885018867 0.0091398718605371 0.026201726433941 0.0372771275338018 0.0043991787336563 5.790511710231963e-05 +Glycosaminoglycan metabolism 15 21 3.2303026711301963 0.0012365923254447 6.563106796116505 14.388349514563108 0.750167459040055 0.1742505874253542 2.387954817808654 2.3973407990867264 1.8682770414846892 0.2409021330213527 3.988049103259445e-10 1.054645038995207e-06 3.154974529334037e-07 9.094204715523703e-10 1.5852687232450577e-07 +Trans golgi network vesicle budding 10 41 3.116184992465801 0.0018320730170517 10.53640776699029 36.62378640776699 0.049458611821428 0.5755399655007756 4.812618396852807 3.083264760841391 1.1838693038940356 0.3533924794481698 1.4902946970872791e-05 0.0003498925816777 4.048374139284611e-06 5.422071643948876e-06 0.0001032946331356 +Cell surface interactions at the vascular wall 12 19 2.9127558275526653 0.0035825461117546 4.95873786407767 15.691747572815531 0.5051863749151446 0.4839549723278067 2.507415479651395 2.585363930808798 0.9576767064205626 0.3154426595544552 0.002758861919529 1.0 0.4925597827158772 0.0266777247012389 2.59737357315436e-05 +Ion channel transport 14 35 2.884265268660219 0.0039232811950913 9.031553398058252 27.74271844660194 0.8980727715308076 0.3472480807052641 4.2752930421976005 3.4432740668393595 1.4212023690700646 0.3452897078102002 0.0016405382358234 0.0610672127355571 0.0442161560616649 0.0141287190006936 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sulfate metabolism 5 7 2.369931514765532 0.017791380431364 1.7936893203883495 4.021844660194175 0.1833102203803382 0.2980238462552717 1.0674618205957698 1.1286251173357766 1.5088456365203304 0.2864106402914596 0.0015498140374225 0.0106429023881486 0.0034893000144238 0.0009276346440678 0.0038758075765755 +Response to elevated platelet cytosolic ca2 9 40 2.361868359442706 0.0181830976049857 8.235436893203884 32.09466019417476 0.5218742391064733 0.474727643525593 3.081483464681404 3.343341539765611 1.0584548796008648 0.3324549758990046 0.000117309092895 0.0003904324769383 0.0005837444150782 4.8364204898706e-05 0.0001373686059673 +Binding and uptake of ligands by scavenger receptors 3 9 2.354255983780289 0.0185598249241922 1.6286407766990292 7.286407766990291 0.4072923013026871 0.3929582954559311 1.6430066853321073 0.8979532869647183 1.127021484187218 0.2797911593020417 0.0009463420108467 0.0802348466038066 0.1515272625734178 0.0006143549700213 0.0078256896811826 +Gpcr ligand binding 3 9 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0.261809046515659 0.5492959535854055 1.0 1.0 0.5079876539292768 0.0022975467393054 +Stimuli sensing channels 6 13 2.230933509549508 0.0256855336637782 3.075242718446602 8.648058252427184 0.6737384899082146 0.3285895756392196 1.7754169999219978 1.9694070657894505 1.2463928142905627 0.307032431313504 0.0033852941785498 0.0148056693212618 0.005693097574516 0.002055769463525 0.0020472170292007 +Transport of inorganic cations anions and amino acids oligopeptides 11 14 2.22758323497855 0.025908319657582 3.45873786407767 9.99514563106796 1.347451847228265 0.1988162564497566 2.1544143797408783 1.7967002462592632 1.0339867286779445 0.2465647399589519 0.0011076389077195 1.0 1.0 0.0039562767661884 0.0185344065780108 +Adora2b mediated anti inflammatory cytokines production 7 10 2.188618774339381 0.0286245600937744 3.7402912621359223 8.405339805825243 -0.1691456153946491 0.589948027598881 2.458002170960783 1.5163416088808164 0.8526380969740552 0.3098662603538845 0.0465174752555924 1.0 1.0 0.1627514901813832 0.0027564644815256 +G protein mediated events 9 15 2.188339597668548 0.028644874552725 3.655339805825242 11.177184466019416 -0.0270702866080933 0.6738973843129692 2.706096251681923 1.8155648068615 0.6685652349930089 0.2665482947114282 0.0932441718455508 1.0 1.0 0.2511786735203468 0.0118494727859131 +Anti inflammatory response favouring leishmania parasite infection 9 16 2.186061571604559 0.0288111009756277 4.533980582524272 13.390776699029129 -0.1101893732527233 0.7034910035510115 3.3856221810800182 2.68494768234556 0.6247749352556544 0.2666500510726559 0.1277174178676254 1.0 1.0 0.3051232152156647 0.0062217625914052 +Heparan sulfate heparin hs gag metabolism 5 8 2.179991538259168 0.0292580887912456 2.4320388349514563 4.83252427184466 0.8003221575390526 0.2230961855611341 1.2648123228701085 1.2708877857521428 1.4628061886044337 0.2633127679646707 0.0015498140374225 0.0106429023881486 0.0034893000144238 0.0009276346440678 0.0038758075765755 +Degradation of the extracellular matrix 4 11 2.175160062276859 0.029618123842096 2.9854368932038833 8.45631067961165 -0.2764356066249684 0.4712903139856545 1.609975442554694 2.058733228327538 1.0124241638389404 0.2958639735684837 0.0645226289288503 0.0306743412959273 0.0165254238564816 0.0457432535763689 0.0526960840113874 +Ldl clearance 3 13 2.171500669816208 0.0298933465737483 3.004854368932039 11.317961165048544 -0.7075477519664274 0.3458777987103926 1.8708223953925376 1.6050187424265143 1.3458663454313908 0.3268587514397556 0.0009463420108467 0.0802348466038066 0.0113213926532688 0.0006143549700213 0.0078256896811826 +Amino acid transport across the plasma membrane 3 5 2.166086958699756 0.0303045425694161 1.6019417475728157 3.9466019417475726 0.6798215426479346 0.3497589750262466 1.2195001827124836 1.03907310581091 1.144086667263588 0.2965730694092905 0.0009463420108467 1.0 1.0 0.0006143549700213 0.0078256896811826 +Interferon alpha beta signaling 3 11 2.1214774471779028 0.0338816438751148 2.9975728155339807 9.393203883495143 0.1840108838382437 0.6467532265432526 2.0247243446658025 0.9351560937065904 0.7549731149771679 0.3103930429476874 0.0092969246962044 1.0 0.2590666885683055 0.0379489226270714 0.0608861307148366 +Antigen presentation folding assembly and peptide loading of class i mhc 2 16 2.11771115725328 0.0341995373683319 4.368932038834951 15.359223300970871 0.4885439583196688 0.552320665891318 2.1553288725341515 1.853123151913033 0.7873077885530996 0.3087027768162914 0.0260894037169127 1.0 0.2070995190727305 0.0193169154759243 0.1078274882909933 +O linked glycosylation 5 7 2.110923563559456 0.0347788823520298 1.766990291262136 4.330097087378641 0.8603336668848929 0.3169450005244383 1.1529100664253755 1.1773621125091884 1.0771631098821022 0.279831511700265 0.2445684315621151 1.0 1.0 0.2064377407436189 0.0255449311307142 +Rnd1 gtpase cycle 10 19 2.094123924388458 0.0362489423755085 3.9854368932038833 14.514563106796116 0.208877848589142 0.4518727246968532 2.1999076665085657 2.249548294118384 1.053267386868326 0.2884669841419 0.0156685252191865 0.0133509861907553 0.004885623522166 0.0106277501006418 6.159496784990413e-07 +Fcgr3a mediated il10 synthesis 6 10 2.086253152693038 0.0369556977999427 2.3276699029126213 6.286407766990291 0.012825656730101 0.648396567831313 1.8765055852366288 1.6737579683570452 0.6956015752224277 0.2747497815194525 0.0232832774509756 1.0 1.0 0.1053546389470493 0.0231565450655555 +Hyaluronan uptake and degradation 2 5 2.084260034683533 0.0371365205375702 1.6893203883495145 4.407766990291262 -0.2953804523839157 0.3437131753624424 0.9087399385919396 0.7232195171442212 1.3605977668387437 0.3004439304685412 0.0009932781732133 0.000647621121882 4.656667989155393e-05 0.0007102815399137 0.0052730305790767 +Hyaluronan metabolism 2 5 2.084260034683533 0.0371365205375702 1.6893203883495145 4.407766990291262 -0.2953804523839157 0.3437131753624424 0.9087399385919396 0.7232195171442212 1.3605977668387437 0.3004439304685412 0.0014601836592373 0.0008300469730069 6.936272072908627e-05 0.0010464818333657 0.0076273123324074 +Cargo recognition for clathrin mediated endocytosis 9 42 2.0841982478597227 0.0371421380740892 8.473300970873787 32.9126213592233 0.0802035091430913 0.5538966462673686 4.054455271697202 4.1286514785567014 1.088296749159732 0.3439390512580828 0.0011842465931248 1.0 9.934540328048928e-05 0.0026901941541905 0.0012638246218667 +Interleukin 3 interleukin 5 and gm csf signaling 6 11 2.07866855467376 0.0376478251253922 2.9854368932038833 7.686893203883495 -0.3832580557302291 0.5164880711408343 1.8020434876701577 2.062499910739022 0.8948886836507619 0.3052993323046413 0.5734351931468765 1.0 1.0 1.0 0.188221571487594 +Laminin interactions 4 6 2.0681800239158887 0.0386230979558446 1.1820388349514563 2.4514563106796117 -0.1747267989791531 0.4408051094089246 1.0535965765247446 1.2809556564230908 1.3052071677595742 0.3169431262072641 0.4684034336908544 1.0 0.1993869387044997 0.4301270919610729 0.0042587077964903 +Autophagy 19 54 2.064210898488303 0.0389977246340902 10.618932038834952 49.09466019417476 0.5991637048381673 0.5478738847433878 5.048592116085888 6.4120843612202885 0.9575127000026346 0.3634200031879806 0.1408900890917273 0.1332928413805449 0.1295090696181635 0.2052986102372402 0.099307933437372 +Non integrin membrane ecm interactions 6 11 2.041240499813 0.0412269279670192 2.3810679611650487 5.682038834951456 -0.0725412144856926 0.5776386594360561 1.652573992657068 1.8534585143755615 0.8819938971562727 0.3098953498776026 0.6383927808138198 1.0 1.0 0.5955662992954859 0.0081074498059467 +Rhoh gtpase cycle 4 23 2.040474319763921 0.0413031062509556 5.62378640776699 21.385922330097088 -0.2806066040328676 0.6300824607687089 3.2248605348047943 2.5540935872085453 0.8188078144197068 0.3180675727064724 0.0104036547903649 0.1457663642848915 0.0376249374527164 0.0411512789917762 0.0038758075765755 +Regulation of insulin secretion 8 14 2.025492546314073 0.042816813065911 3.815533980582525 12.240291262135925 -0.2451612480519125 0.6549896087693952 2.567525244260177 2.096698262623107 0.6535683906421994 0.2699338419478539 0.3746184765837701 1.0 1.0 0.6911948368646196 0.0813065502215209 +Neutrophil degranulation 43 193 2.0228755061014887 0.0430859844557283 38.10436893203884 171.8640776699029 0.1126763475494757 0.6323671699869864 12.87265033097306 10.728827462142076 1.3059870522330337 0.3651237180041888 1.4339790109309657e-19 6.675706104145088e-14 8.209561073683706e-20 5.199693182065497e-19 9.344814538195112e-14 +Diseases of metabolism 15 57 2.009762201264236 0.0444563631253858 10.91747572815534 43.34708737864078 -1.309770160040866 0.249752463847892 4.21831253208471 4.914651787893876 1.4623549850590434 0.3091348346884224 4.555249469245893e-07 3.1040597476984213e-06 4.47821637049605e-08 9.46002030047262e-08 1.6700232578937635e-05 +Mhc class ii antigen presentation 15 61 2.0088474127997187 0.0445533182948993 14.065533980582524 53.91990291262136 0.0378305751056327 0.7050016235886306 7.205585512568872 4.251886159447844 0.7481875393236335 0.3070805603530936 0.0538501803344362 0.0014196759684226 0.0027125023591425 0.0337698983302116 0.052942646452148 +Synaptic adhesion like molecules 6 7 1.990884561999134 0.0464935798168315 1.6674757281553398 5.951456310679611 1.045730316736721 0.2890276876766184 1.4188777313077996 1.1438195320406324 0.8614150619700692 0.2468687149363868 0.0027551051088643 1.0 1.0 0.2356930071839008 0.0013678067399173 +Aquaporin mediated transport 4 7 1.983785927272279 0.0472797096063333 2.029126213592233 5.621359223300971 0.1535607182051645 0.6084442620321643 1.4972875843617088 1.3625825340950013 0.8166558547649294 0.3116717398712245 0.0322196793383797 1.0 1.0 0.1292409073430241 0.1292339698967795 +Transport of bile salts and organic acids metal ions and amine compounds 2 5 1.974847613626851 0.0482854438467317 1.8349514563106797 3.995145631067961 1.0286208624357371 0.2748571167414633 1.258733277411433 1.3329199016551914 1.161382969627279 0.2758406238802445 0.2143905805206482 1.0 1.0 0.1800390494619342 0.2007579256502274 +Metabolism of fat soluble vitamins 4 8 1.9710837605909324 0.0487142959058062 1.6650485436893203 4.580097087378641 0.3536798037155611 0.3331745511018804 1.178052427490116 1.3130753903966457 1.3422038796699125 0.2910915635007025 0.0426927090881441 1.0 0.031373049189738 0.0319451393300601 0.0495301536946375 +Visual phototransduction 2 9 1.9651823968573336 0.0493931306072481 2.371359223300971 7.507281553398058 -0.0306149653302486 0.4547274497453649 1.4297311503288843 1.879228665447173 1.068260637854754 0.2987144157403565 0.0932441718455508 1.0 0.0563311776114605 0.0713646261968556 0.3060121360259066 +Diseases associated with glycosylation precursor biosynthesis 2 10 1.9642100645664908 0.0495057361263455 2.504854368932039 7.854368932038835 -0.2470350872852216 0.3703940384904795 1.636203196770404 1.0039510972336867 1.211038284186021 0.274954505205811 0.008459922663953 0.0756950383436983 0.000440337804097 0.0061570039439817 0.0395358442373242 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..839c962254c705a8348146b62b3e4ab1c2d85fb8 --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 1425, + "title": "Average number of proteins per term", + "value": 20.920701754385966 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..26ecf87c4765231a893c7acaed7a6b1c06b516d1 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5aea7fcecdc175c34104d5283cd49ff47b38a933 --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,457 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Sphingolipid metabolism 0.84491178541116 3.669771215428867 0.0002427676459835 0.2924775328759204 0.3459438955265196 29 Q96G23,P16278,P10619,P15289,Q9NRA0,P06865,P27544,Q13510,P04062,P07686,O15269,P07602,P06280,Q06136,Q16739,P17900,Q99519 17 +Glycosphingolipid metabolism 0.9291929016314266 3.4436548067496164 0.0005739079322906 0.5587102411231314 0.3514800429678337 17 P16278,P10619,P06865,Q13510,P04062,P07686,P07602,P06280,Q16739,P17900,Q99519 11 +Extracellular matrix organization 0.7362884512252088 3.3743292768282127 0.0007399579851954 0.6517485289308774 0.3514800429678337 38 P17301,P35613,P06756,P07711,O75718,P13591,P07858,Q32P28,P14543,Q92542,Q08722,O15460,Q14118,O14936,P05067,Q9Y624 16 +Glycosaminoglycan metabolism 0.8349840460285655 3.2303026711301963 0.0012365923254447 0.8285107145273191 0.3902944684575391 21 P16278,O43505,P34059,P54802,P51688,Q8TB61,P06865,Q9P2E5,Q8NCH0,O60512,P07686,Q7LGA3,P15586,P08236,Q8N6G5 15 +Trans golgi network vesicle budding 0.6912683191492226 3.116184992465801 0.0018320730170517 0.9266929485223504 0.3902944684575391 41 Q99523,P02792,P20645,P02786,O00115,P15586,P11717,O75976,P05067,O43493 10 +Cell surface interactions at the vascular wall 0.7972961541920749 2.9127558275526653 0.0035825461117546 0.9939897851813216 0.3902944684575391 19 P35613,P06756,Q92896,P14174,Q08722,Q9UNN8,P08195,P78310,P07947,P05026,Q9Y624,P05556 12 +Ion channel transport 0.6662684522348382 2.884265268660219 0.0039232811950913 0.9963083116134456 0.3902944684575391 35 Q93050,Q8TEL6,P27105,Q15904,P51790,Q4KMQ2,Q04656,Q9C0H2,Q9Y487,P05026,Q9HD20,P51798,Q9NQ11,Q86WC4 14 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.738406915089656 2.777747526669565 0.0054737131153985 0.9995989670662332 0.3902944684575391 22 Q08431,Q8NBJ4,Q9BTY2,Q06481,P05067,O43493 6 +Diseases of carbohydrate metabolism 0.8761091751938117 2.767779266940088 0.0056439667354042 0.999685785470632 0.3902944684575391 12 P16278,P34059,P54802,P10253,P15586,P08236 6 +Keratan sulfate keratin metabolism 0.966110812264662 2.703876570370807 0.0068535741912147 0.9999445464100936 0.3902944684575391 7 P16278,P34059,P06865,O60512,P07686,P15586 6 +Interferon gamma signaling 0.7690682652508082 2.663482941895523 0.0077336332804189 0.9999843221612326 0.3902944684575391 17 P04439,P01889,P10321,P15260,P23458 5 +Plasma lipoprotein clearance 0.773031537682119 2.637422450380699 0.0083538724067675 0.9999935682906606 0.3902944684575391 16 P01130,P61916,Q8WTV0,O15118,P98155 5 +Plasma lipoprotein assembly remodeling and clearance 0.7108939670480893 2.5624464054529787 0.0103937627978818 0.9999996580567748 0.3902944684575391 21 P01130,P61916,P38571,Q8WTV0,O15118,P98155 6 +Slc mediated transmembrane transport 0.6636454752155304 2.5615406838127956 0.0104209035236197 0.9999996711629172 0.3902944684575391 28 P35613,Q99808,Q8TB61,Q9H2J7,Q96QD8,P08195,P55011,P11166,P30825,Q92581,Q15043,Q9Y6M7 12 +Keratan sulfate degradation 0.987903225806452 2.519705005126366 0.0117453222756844 0.9999999512300723 0.3902944684575391 5 P06865,P16278,P34059,P15586 4 +Mucopolysaccharidoses 0.948373218607146 2.472709620498952 0.0134093048099233 0.999999995581787 0.3902944684575391 6 P16278,P34059,P54802,P08236,P15586 5 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.9074771382463784 2.4716375738868255 0.0134495790703961 0.9999999958314708 0.3902944684575391 7 P04439,P01889,P10321,Q5KU26,P78310,Q92692 6 +Lysosome vesicle biogenesis 0.7399996651979585 2.468748524811896 0.0135586464942289 0.9999999964390952 0.3902944684575391 16 P05067,O00115,P20645,P15586 4 +Golgi associated vesicle biogenesis 0.6188391030032272 2.466795365844534 0.0136328241962666 0.999999996800948 0.3902944684575391 33 P02792,Q99523,P02786,P11717,O75976,O43493 6 +Toll like receptor cascades 0.6102030469775876 2.452390344049242 0.0141910625117755 0.9999999985721898 0.3902944684575391 34 P05067,P07711,P07858 3 +Diseases of glycosylation 0.656255763114621 2.449216728988852 0.0143167273533957 0.9999999988093728 0.3902944684575391 26 P16278,O43505,P06865,Q8NCH0,P07686,Q14118,P10619,Q99519 8 +Amyloid fiber formation 0.8802170138874317 2.439577625996215 0.0147044431000753 0.9999999993203312 0.3902944684575391 8 P05067,Q08431,Q92673,Q9Y287 4 +Endosomal vacuolar pathway 0.964784946236562 2.431619820785669 0.0150314756163447 0.9999999995765012 0.3902944684575391 5 P10321,Q9UIQ6,P07711,P04439 4 +Pink1 prkn mediated mitophagy 0.8583733251912117 2.4286876207251025 0.0151535823032797 0.9999999996450836 0.3902944684575391 9 Q13501,P21796,Q8N4H5 3 +Mitophagy 0.793283408266182 2.3936356662838745 0.0166823105610156 0.9999999999612084 0.3902944684575391 12 Q13501,P21796,Q8N4H5 3 +Chondroitin sulfate dermatan sulfate metabolism 0.8823314942991843 2.3699315147655313 0.017791380431364 0.9999999999922315 0.3902944684575391 7 P06865,Q9P2E5,Q8NCH0,P07686,Q8N6G5 5 +Response to elevated platelet cytosolic ca2 0.5859472066802557 2.361868359442706 0.0181830976049857 0.9999999999956 0.3902944684575391 40 Q9Y6I9,P13473,P07602,Q06481,Q6YHK3,Q08380,P05067,O60245,O43852 9 +Binding and uptake of ligands by scavenger receptors 0.8408622189621042 2.3542559837802894 0.0185598249241922 0.9999999999974534 0.3902944684575391 9 Q5KU26,Q8WTV0,Q07954 3 +Gpcr ligand binding 0.8403255361363865 2.351963717833326 0.0186745963741865 0.9999999999978444 0.3902944684575391 9 P42892,P05067,P07602 3 +Sialic acid metabolism 0.9163437153015674 2.347441883814757 0.0189028217930791 0.9999999999984523 0.3902944684575391 6 P10619,P16278 2 +Ecm proteoglycans 0.8568339966589349 2.3424607106864905 0.0191570508641825 0.9999999999989304 0.3902944684575391 8 P17301,P06756,P13591,Q14118,P05067,P05556 6 +Integrin cell surface interactions 0.9072331271847256 2.311466904944743 0.020807079138462 0.9999999999999029 0.3902944684575391 6 P17301,P35613,P06756,Q08722,Q9Y624 5 +Collagen formation 0.7258458152800579 2.3050304396863033 0.0211648686822725 0.9999999999999424 0.3902944684575391 15 Q32P28,P07711,O75718,P07858 4 +Trafficking and processing of endosomal tlr 0.9837207485849346 2.3022422671328417 0.021321513585284 0.999999999999954 0.3902944684575391 4 P07711,P07858 2 +G alpha i signalling events 0.6345584528883685 2.285208493191456 0.0223006054334937 0.999999999999989 0.3902944684575391 25 P08754,P22694,P10644,P07602,P04899,O60266,P63096,P17612,P05067,P29992,O43865 11 +Class a 1 rhodopsin like receptors 0.8549889378505688 2.257878987869244 0.0239532049551509 0.999999999999999 0.3902944684575391 7 P05067,P07602 2 +Peptide ligand binding receptors 0.8549889378505688 2.257878987869244 0.0239532049551509 0.999999999999999 0.3902944684575391 7 P05067,P07602 2 +Vitamin d calciferol metabolism 0.9154977269552276 2.240803839254115 0.0250387841606305 0.9999999999999998 0.3902944684575391 5 Q99538,P98164 2 +Sphingolipid de novo biosynthesis 0.7587816399214445 2.2323035547885923 0.0255949071006276 1.0 0.3902944684575391 12 Q96G23,Q9NRA0,P27544,O15269,Q06136 5 +Stimuli sensing channels 0.7433433649159806 2.2309335095495073 0.0256855336637782 1.0 0.3902944684575391 13 Q8TEL6,P27105,P51790,Q9C0H2,P51798,Q86WC4 6 +Transport of inorganic cations anions and amino acids oligopeptides 0.726978981010878 2.22758323497855 0.025908319657582 1.0 0.3902944684575391 14 Q70HW3,Q9UBX3,Q9H2J7,Q96QD8,Q15758,Q9Y666,P08195,P30825,P55011,Q92581,Q9Y6M7 11 +Adora2b mediated anti inflammatory cytokines production 0.7851649702145765 2.188618774339381 0.0286245600937744 1.0 0.3902944684575391 10 P08754,P22694,P10644,P04899,O60266,P17612,P63096 7 +G protein mediated events 0.703170822997111 2.188339597668548 0.028644874552725 1.0 0.3902944684575391 15 P08754,P22694,P10644,P04899,O60266,P17612,P63096,P29992,O43865 9 +Anti inflammatory response favouring leishmania parasite infection 0.6862176752013861 2.186061571604559 0.0288111009756277 1.0 0.3902944684575391 16 P08754,P22694,P10644,P04899,O60266,P17612,P63096,P07947,O43865 9 +Heparan sulfate heparin hs gag metabolism 0.8183373040596857 2.179991538259168 0.0292580887912456 1.0 0.3902944684575391 8 P16278,P51688,P54802,Q7LGA3,P08236 5 +Degradation of the extracellular matrix 0.7646102517295952 2.175160062276859 0.029618123842096 1.0 0.3902944684575391 11 Q92542,P14543,P07711,P07858 4 +Ldl clearance 0.7311581450966554 2.1715006698162074 0.0298933465737483 1.0 0.3902944684575391 13 P01130,P61916,O15118 3 +Amino acid transport across the plasma membrane 0.896481873188203 2.166086958699756 0.0303045425694161 1.0 0.3902944684575391 5 Q9H2J7,Q96QD8,P30825 3 +Hs gag degradation 0.9478634775597896 2.1648146177806 0.0304018849114293 1.0 0.3902944684575391 4 P54802,P16278,P08236 3 +Interferon alpha beta signaling 0.753028048292854 2.1214774471779028 0.0338816438751148 1.0 0.4126610471969114 11 P10321,P04439,P01889 3 +Antigen presentation folding assembly and peptide loading of class i mhc 0.6734992113528941 2.11771115725328 0.0341995373683319 1.0 0.413002887710788 16 P10321,P04439 2 +O linked glycosylation 0.8196820770851535 2.110923563559456 0.0347788823520298 1.0 0.4156034932429799 7 Q86SF2,O43505,Q10472,Q14118,Q9Y2G5 5 +Rnd1 gtpase cycle 0.6466384141012282 2.094123924388458 0.0362489423755085 1.0 0.4158771380130535 19 Q9BXS4,O43396,P38159,P29317,P02786,Q8TAA9,O75976,Q9NNW5,Q14254,Q9ULH0 10 +Fcgr3a mediated il10 synthesis 0.7624675786921455 2.086253152693038 0.0369556977999427 1.0 0.4158771380130535 10 P22694,P10644,O60266,P17612,P07947,O43865 6 +Hyaluronan uptake and degradation 0.8758304768912064 2.084260034683533 0.0371365205375702 1.0 0.4158771380130535 5 P06865,P07686 2 +Hyaluronan metabolism 0.8758304768912064 2.084260034683533 0.0371365205375702 1.0 0.4158771380130535 5 P06865,P07686 2 +Cargo recognition for clathrin mediated endocytosis 0.5468323535575123 2.0841982478597227 0.0371421380740892 1.0 0.4158771380130535 42 P01130,O43493,P20645,P02786,P00533,P51809,P11717,Q14108,P98164 9 +Interleukin 3 interleukin 5 and gm csf signaling 0.7438461817237563 2.0786685546737593 0.0376478251253922 1.0 0.4158771380130535 11 P62993,P17252,P23458,O00459,P17612,P07947 6 +Laminin interactions 0.8466026802352624 2.0681800239158887 0.0386230979558446 1.0 0.4224922809451509 6 P17301,P06756,P14543,P05556 4 +Autophagy 0.5252505397598529 2.064210898488303 0.0389977246340902 1.0 0.4224922809451509 54 Q9BUF5,Q7Z3C6,Q13501,Q9NS69,P13473,Q9Y3E7,Q8IWA4,Q9Y2Q5,P60520,P67870,Q9UK41,O43237,Q9H9H4,Q9BVA1,Q5MNZ6,Q8N4H5,P21796,Q8TDY2,P08670 19 +Non integrin membrane ecm interactions 0.7358572800102823 2.0412404998129996 0.0412269279670192 1.0 0.4308943445526571 11 P17301,P06756,Q14118,O14936,P07942,P05556 6 +Rhoh gtpase cycle 0.6033777378368645 2.040474319763921 0.0413031062509556 1.0 0.4308943445526571 23 Q9BXS4,P02786,P27105,Q9Y6M7 4 +Regulation of insulin secretion 0.6871040301615264 2.025492546314073 0.042816813065911 1.0 0.4354434599249138 14 O43865,P22694,P10644,P04899,P17612,P63096,P29992,P11166 8 +Inactivation of cdc42 and rac1 0.9118908672873512 2.025073931904812 0.0428597732099311 1.0 0.4354434599249138 4 O94813 1 +Neutrophil degranulation 0.622802637277418 2.0228755061014887 0.0430859844557283 1.0 0.4354434599249138 193 Q93050,O75629,P42785,P14174,P07858,P01889,O00584,Q9BTY2,P13473,P07602,P06280,P15586,P17900,P48960,P16278,P34059,P15289,P53634,P61916,Q13510,O00462,P10253,P07686,Q92820,P08236,P11717,O15260,P10619,P02792,P04439,Q8WVQ1,Q9NQX7,Q08722,Q9NV96,Q9Y6X5,P11279,P04066,Q99519,O00754,P27105,P10321,Q92542,O00560 43 +Diseases of metabolism 0.5123851032640001 2.0097622012642353 0.0444563631253858 1.0 0.4408922122932752 57 Q9NPF0,P16278,O43505,P34059,P54802,P51688,P06865,Q8NCH0,P10253,P07686,Q14118,P15586,P08236,P10619,Q99519 15 +Mhc class ii antigen presentation 0.5025717168630367 2.0088474127997187 0.0445533182948993 1.0 0.4408922122932752 61 Q99538,P07711,Q9BXW6,Q9BUF5,O43237,P07858,P53634,P33176,Q9BVA1,P51149,Q9NSK0,Q02241,P10619,Q9H0H5,Q9UBX1 15 +Synaptic adhesion like molecules 0.7912856374395029 1.990884561999134 0.0464935798168315 1.0 0.4537900769793491 7 O95197,Q12959,P10586,O75955,P41440,Q14254 6 +Aquaporin mediated transport 0.7896183806377034 1.983785927272279 0.0472797096063333 1.0 0.4551958359900549 7 P10644,O60266,P17612,P22694 4 +Transport of bile salts and organic acids metal ions and amine compounds 0.8484884870723872 1.974847613626851 0.0482854438467317 1.0 0.4551958359900549 5 Q15043,Q9H2J7 2 +Scavenging by class a receptors 0.8987766075489101 1.9736807465741923 0.0484180557694751 1.0 0.4551958359900549 4 Q5KU26 1 +Metabolism of fat soluble vitamins 0.769922261428339 1.9710837605909324 0.0487142959058062 1.0 0.4551958359900549 8 P98164,P01130,Q8N0U8,Q07954 4 +Visual phototransduction 0.7518988098576547 1.965182396857334 0.0493931306072481 1.0 0.4551958359900549 9 P01130,P98164 2 +Diseases associated with glycosylation precursor biosynthesis 0.7357686026493987 1.9642100645664908 0.0495057361263455 1.0 0.4551958359900549 10 P10619,P16278 2 +Syndecan interactions 0.78299413334573 1.9555269468811831 0.0505209059752165 1.0 0.4551958359900549 7 P17301,P06756,O14936,P05556 4 +Gaba receptor activation 0.8413226044765112 1.94597409748699 0.051657851145578 1.0 0.4600777367653048 5 P04899,O60266,P63096 3 +Sensory perception 0.5630881886354233 1.9354037383033624 0.0529407709384568 1.0 0.4646712996880784 29 P01130,O14936,O60266,P98164,Q07954,P56545 6 +Regulation of ifng signaling 0.8130374864920903 1.9306348286486543 0.0535282275785622 1.0 0.4646712996880784 6 P15260 1 +Protein protein interactions at synapses 0.6369121613380033 1.9178329576997903 0.0551321953122296 1.0 0.4646712996880784 16 Q14168,P10586,O75955,O14936,P41440 5 +Adenylate cyclase inhibitory pathway 0.8787960225745735 1.894938422621644 0.0581005600786834 1.0 0.4646787666210866 4 P04899,O60266,P63096 3 +Gaba b receptor activation 0.8787960225745735 1.894938422621644 0.0581005600786834 1.0 0.4646787666210866 4 P04899,O60266,P63096 3 +Signal transduction by l1 0.6884137254753354 1.892907475936656 0.0583701748948592 1.0 0.4646787666210866 12 P06756,P13591,P00533,O14786,P05556 5 +Intra golgi traffic 0.6024843430299129 1.881264892284828 0.0599358942336274 1.0 0.4647551176799018 20 P33908,Q99747,Q96JB2,Q16706,O43752,O00461,Q13190,O95249,O95721,P54920,O14653 11 +Vasopressin regulates renal water homeostasis via aquaporins 0.8003976612894214 1.8783256528459051 0.0603366293128293 1.0 0.4647551176799018 6 P10644,O60266,P17612,P22694 4 +Glucagon signaling in metabolic regulation 0.8003976612894214 1.8783256528459051 0.0603366293128293 1.0 0.4647551176799018 6 P10644,O60266,P17612,P22694 4 +Pka activation in glucagon signalling 0.8003976612894214 1.8783256528459051 0.0603366293128293 1.0 0.4647551176799018 6 P10644,O60266,P17612,P22694 4 +Pka mediated phosphorylation of creb 0.8003976612894214 1.8783256528459051 0.0603366293128293 1.0 0.4647551176799018 6 P10644,O60266,P17612,P22694 4 +Opioid signalling 0.6009787783466197 1.8722408347939543 0.0611732920204186 1.0 0.4686663501564332 20 P08754,P22694,P10644,P04899,O60266,P17612,P63096,P29992,O43865 9 +Dap12 interactions 0.7574083496038971 1.8455609217759927 0.0649559850384522 1.0 0.4897475062422985 7 P10321,O00459,P01889 3 +Role of abl in robo slit signaling 0.8112571407353395 1.8239654628964588 0.0681572937475922 1.0 0.5058549145329114 5 O94813 1 +Collagen degradation 0.9983883964544724 1.810106491633092 0.0702792744860794 1.0 0.514295524280932 2 P07711 1 +Ret signaling 0.7322850544043946 1.805206310977364 0.0710424037523911 1.0 0.514295524280932 8 O00459,P62993,P17612,P22694 4 +Rhoa gtpase cycle 0.4940416858836904 1.7967569779776245 0.0723742090419892 1.0 0.5164439298859362 54 P30519,P27105,P41440,Q07021,O15173,Q15904,P43121,O75955,P02786,Q8NBN3,O00459,Q9Y4F1,Q9H0H5,Q8TAA9,Q14254,O60245 16 +Assembly of collagen fibrils and other multimeric structures 0.8540127691813499 1.796567532581382 0.072404302621913 1.0 0.5164439298859362 4 P07711 1 +Neuronal system 0.4860380908707832 1.7960701656871063 0.0724833585804822 1.0 0.5164439298859362 58 Q96QD8,P22694,O75955,P63096,Q14168,P10644,P04899,Q14012,P17612,O60266,Q96RD7,Q9BVA1,P08754,P21964,P10586,O14936,Q14254,P17252,Q12959,P41440 20 +G alpha s signalling events 0.7791528040059588 1.7897940335844145 0.0734870287075797 1.0 0.5209901288970205 6 P04899,O60266,P63096 3 +O linked glycosylation of mucins 0.8020838997753873 1.7864707364386685 0.074023071304984 1.0 0.5221924584633779 5 Q86SF2,Q10472,O43505 3 +N glycan antennae elongation in the medial trans golgi 0.8470841171727859 1.768935152891039 0.0769046969835631 1.0 0.5289908199249824 4 P04066,Q16706,O60512 3 +Metabolism of carbohydrates 0.4950638858238517 1.7649811511147575 0.077566933605661 1.0 0.5289908199249824 112 O43505,Q04446,Q8TB61,P22694,Q7LGA3,P15586,P16278,P34059,P54802,P06865,O00462,P10253,P07686,P08236,P11166,P51688,Q8NCH0,O94766,Q8N6G5,O00754,Q9P2E5,O60512,Q93100,Q9BTX1 24 +Cs ds degradation 0.9871071716357774 1.7641499753585472 0.0777067323945877 1.0 0.5289908199249824 2 P06865 1 +Diseases associated with glycosaminoglycan metabolism 0.7704037549483792 1.7531188156760698 0.0795816144551604 1.0 0.5374587706094958 6 P06865,P07686,Q8NCH0 3 +Basigin interactions 0.7325771616720059 1.737629073431583 0.0822761935590055 1.0 0.5529675922463857 7 P35613,P08195,P05556 3 +Cell cell junction organization 0.6867228762540776 1.7354897059145495 0.0826541032620913 1.0 0.5529675922463857 10 Q9BY67,P19022,O60716,Q9Y624,Q92692 5 +Synthesis of substrates in n glycan biosythesis 0.5825126178337483 1.7187188849195905 0.085665571636581 1.0 0.5608513685591845 19 P10619,P16278 2 +Creb1 phosphorylation through the activation of adenylate cyclase 0.7850508023018509 1.716534002875716 0.086064350029531 1.0 0.5608513685591845 5 P10644,P17612,P22694 3 +Nrif signals cell death from the nucleus 0.9715283373623458 1.700574890752342 0.0890228424575021 1.0 0.5688679394705854 2 Q13501 1 +Synthesis of pips at the early endosome membrane 0.7070944101780127 1.6925518669470865 0.090540799560594 1.0 0.5697699840122722 8 Q9NYA4,Q9BTU6,Q8TCG2,Q13614 4 +Eph ephrin mediated repulsion of cells 0.6224641182510053 1.687194866840951 0.0915658881165057 1.0 0.5697877317293483 14 Q15375,P29317,Q92542 3 +Regulation of commissural axon pathfinding by slit and robo 0.9664249261348372 1.6797250985385894 0.0930108141555412 1.0 0.5746135483136986 2 O94813 1 +Iron uptake and transport 0.5752610676481081 1.6752292116187886 0.0938892682151406 1.0 0.5746135483136986 19 Q93050,P02792,P30519,Q15904,P02786 5 +Keratan sulfate biosynthesis 0.9648133225893092 1.673138900369037 0.0942999551079206 1.0 0.5746135483136986 2 O60512 1 +Adherens junctions interactions 0.7024959167048492 1.6718516960223642 0.0945535698831228 1.0 0.5746135483136986 8 Q9BY67,P19022,O60716,Q92692 4 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.7173326249822034 1.670801810749461 0.0947608307745397 1.0 0.5746135483136986 7 O00459,P31751,O14654 3 +Selective autophagy 0.5159676055192752 1.6647965147066672 0.0959533595269193 1.0 0.5793793954485593 31 P21796,O43237,Q9BVA1,Q9BUF5,Q13501,Q9NS69,Q8N4H5,P67870,P08670 9 +Signal amplification 0.7153139357078088 1.6619214660838002 0.096528521995981 1.0 0.5797059411969175 7 P08754,Q13685,Q14344,P04899,P63096 5 +Transferrin endocytosis and recycling 0.6543770518553929 1.6500111430565096 0.098940657000581 1.0 0.5850225569536432 11 Q93050,P02786,Q15904 3 +Regulation of kit signaling 0.8159459096737764 1.6441126338175611 0.1001529387726534 1.0 0.5853852143653447 4 P07947,P62993 2 +Signaling by erbb4 0.6665465843178138 1.6397556935941269 0.1010559738483332 1.0 0.5853852143653447 10 Q96J02,P00533,Q92542,P46934 4 +Death receptor signalling 0.5202155013474867 1.636049303610964 0.1018292691103135 1.0 0.5864562666469567 29 Q13501,Q86VP1 2 +Dag and ip3 signaling 0.6513041698241123 1.634928830753244 0.1020639678094352 1.0 0.5864562666469567 11 P22694,P10644,O60266,P17612,O43865 5 +Activation of rac1 0.7647640276316898 1.632733974013816 0.1025249588063528 1.0 0.5867392220845492 5 O94813 1 +Ctla4 inhibitory signaling 0.7074527021234506 1.627272081970396 0.1036793245219058 1.0 0.5886176790586289 7 P31751,Q16537 2 +Regulation of signaling by cbl 0.737527590145151 1.614243783826516 0.1064745584166799 1.0 0.5899107958010666 6 P07947,O00459,P62993 3 +Collagen biosynthesis and modifying enzymes 0.6448611100511816 1.6032319072342929 0.1088834635040283 1.0 0.5916569118552404 11 O75718,Q32P28 2 +G alpha z signalling events 0.7341986783014799 1.6000935430327343 0.1095778332094747 1.0 0.5916569118552404 6 P04899,O60266,P08754,P63096 4 +Noncanonical activation of notch3 0.943862476497452 1.5874495691912556 0.1124108601922051 1.0 0.6022010367439561 2 Q92542 1 +Plasma lipoprotein assembly 0.8007894149556646 1.583017847546856 0.1134173965334568 1.0 0.603058918134985 4 P17612,P22694 2 +Notch2 activation and transmission of signal to the nucleus 0.9401020682245544 1.5720600910264726 0.1159366158503294 1.0 0.6031211141342604 2 Q92542 1 +Rac3 gtpase cycle 0.4828212309922771 1.5705579544796304 0.1162853627701991 1.0 0.6031211141342604 41 Q14126,Q9Y6W5,P29317,O15173,Q9UQB8,P43121,P02786,O00459,P50402,Q8TAA9,Q9H0H5,P05556 12 +Chondroitin sulfate biosynthesis 0.9374160623153422 1.561066724121997 0.1185080083912932 1.0 0.6031211141342604 2 Q8N6G5 1 +Diseases associated with o glycosylation of proteins 0.9403546480386884 1.5458599285892816 0.1221383999629608 1.0 0.6150078443364635 3 Q14118,O43505 2 +Signaling by vegf 0.4800664234674628 1.5314509029960652 0.1256579917739728 1.0 0.6226631096092233 35 P06756,P17252,Q9Y6W5,Q14185,Q9UQB8,P31751,P42345,P22694,Q13685,O00459,P46108,P17612,O14786,O60716,O43865 15 +Glucagon like peptide 1 glp1 regulates insulin secretion 0.7175759987551329 1.5292125392316047 0.1262117630569044 1.0 0.6226631096092233 6 P10644,P17612,P22694 3 +Clathrin mediated endocytosis 0.4286165527114878 1.5289354449480614 0.1262804481944319 1.0 0.6226631096092233 70 P01130,Q9UKS6,O43493,P20645,P02786,P00533,P51809,P11717,Q14108,P98164 10 +Chl1 interactions 0.7856750232700123 1.5219091624467993 0.1280318430583547 1.0 0.6291219874419153 4 P17301,O14786 2 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.5906346335918498 1.5159129210356674 0.1295413726455443 1.0 0.6321796439037695 14 Q96RD7,P05067,Q96J02 3 +Cytosolic sulfonation of small molecules 0.7360940643222492 1.5134736767048778 0.130159382648433 1.0 0.6330277142457923 5 Q8TB61,Q9NX62 2 +Triglyceride metabolism 0.6806018134397972 1.5081551509562805 0.1315148227672131 1.0 0.6351242038091934 7 Q9HCL2,P43304,P17612,P22694 4 +Mitochondrial protein import 0.4797712508723246 1.4926286778403328 0.1355344122404915 1.0 0.6351242038091934 34 P21796,Q8N4H5,Q99595 3 +Ca dependent events 0.6355060529072358 1.4907349194419064 0.1360311043023814 1.0 0.6351242038091934 10 P10644,O60266,P17612,P22694 4 +Intrinsic pathway of fibrin clot formation 0.92022562449638 1.4907077304649918 0.1360382456053173 1.0 0.6351242038091934 2 P42785 1 +Rhoj gtpase cycle 0.4961860904329839 1.4906442071623835 0.1360549314049175 1.0 0.6351242038091934 30 P27105,Q86VI3,P51149,O00308,Q15758,O00161,P02786,O00459,Q5T2T1,Q8TAA9,Q9Y6M7 11 +Cell death signalling via nrage nrif and nade 0.6082026916321243 1.489390510872704 0.1363845658706057 1.0 0.6351242038091934 12 Q13501 1 +Activated notch1 transmits signal to the nucleus 0.918345420359932 1.4830136863826056 0.1380707745116987 1.0 0.6381433450150448 2 Q92542 1 +Rap1 signalling 0.7283158344590195 1.4809720848458108 0.138614012356816 1.0 0.6381433450150448 5 P17612,P22694 2 +Formation of fibrin clot clotting cascade 0.920472864051584 1.470573510441234 0.1414064921041584 1.0 0.6443388442404718 3 Q9UNN8,P42785 2 +Nectin necl trans heterodimerization 0.9121676067687337 1.4577380593414289 0.1449127571349446 1.0 0.6555577108485593 2 Q92692 1 +Leishmania infection 0.4640236222429227 1.4535523244329596 0.1460704629437221 1.0 0.6572217057424453 47 O14641,P62993,P08754,P17252,Q9Y6W5,Q14185,Q9UQB8,P22694,P10644,P04899,O60266,P17612,P63096,P07947,O43865,P05067 16 +Pecam1 interactions 0.7686938903191076 1.4530747385437754 0.1462030040142843 1.0 0.6572217057424453 4 P06756 1 +Ion transport by p type atpases 0.5889252413242274 1.4454143221519369 0.1483415428843491 1.0 0.6633212712725859 13 Q04656,P98194,Q9NQ11,Q9HD20,P05026 5 +Ddx58 ifih1 mediated induction of interferon alpha beta 0.5373992157826246 1.4448825910716292 0.1484908670427753 1.0 0.6633212712725859 19 P05067,Q86VP1 2 +Downregulation of erbb4 signaling 0.9067955949503078 1.4357671829518055 0.1510686008897677 1.0 0.6671763813808205 2 Q96J02 1 +Extra nuclear estrogen signaling 0.5869682880942717 1.4350328631491518 0.1512777331111772 1.0 0.6671763813808205 13 P08754,P31751,P00533,P04899,P63096 5 +Platelet adhesion to exposed collagen 0.906258393768465 1.4335705929271036 0.1516948403981655 1.0 0.6671763813808205 2 P17301 1 +Rhoq gtpase cycle 0.4907666096502969 1.424593533892332 0.1542747302426863 1.0 0.6714036066512299 29 P27105,Q86VI3,P51149,O00308,Q15758,O00161,P02786,Q5T2T1,Q8TAA9,Q9Y6M7 10 +Role of phospholipids in phagocytosis 0.6929702958596219 1.4236748419857346 0.1545406196362129 1.0 0.6714036066512299 6 Q8IV08,O00459 2 +Signaling by notch2 0.906144861674302 1.4162930545428587 0.1566897205144022 1.0 0.6786712818632923 3 Q92542 1 +Rhob gtpase cycle 0.4833944081840719 1.3966340573132914 0.1625236433152157 1.0 0.6918290488237431 30 P27105,P41440,P43121,P02786,O75955,O00459,Q14254,Q8TAA9,Q9H0H5,O60245 10 +N glycan trimming and elongation in the cis golgi 0.8971259736771479 1.3962457197290428 0.1626405132322483 1.0 0.6918290488237431 2 Q5SRI9 1 +Retrograde transport at the trans golgi network 0.5164769119203435 1.3898222152131967 0.1645828704391572 1.0 0.6938938484045502 21 O43752,Q99747,P53365,P20645,P51151,P11717,O43493 7 +Notch3 activation and transmission of signal to the nucleus 0.7054787268929933 1.3852561557048813 0.1659741550996316 1.0 0.6956269735793386 5 P67809,Q92542 2 +Irs mediated signalling 0.7043795399320043 1.380639903878879 0.1673897075989967 1.0 0.6983776531708739 5 O00459,P31751 2 +Ripk1 mediated regulated necrosis 0.5760785647200232 1.37709837770482 0.1684818342173835 1.0 0.6983776531708739 13 O75955,O00560,P41440 3 +P75 ntr receptor mediated signalling 0.5366045890598158 1.374170760309667 0.1693886759394607 1.0 0.6983776531708739 17 Q13501 1 +Adrenaline noradrenaline inhibits insulin secretion 0.8909481600859499 1.371018813134331 0.1703690914584466 1.0 0.6983776531708739 2 P04899 1 +Glycogen storage diseases 0.7471763801949199 1.365662566974523 0.1720448986498914 1.0 0.6983776531708739 4 P10253 1 +Robo receptors bind akap5 0.7464285483324893 1.3626221570067412 0.1730016221539076 1.0 0.6983776531708739 4 P17612,P22694 2 +Negative regulators of ddx58 ifih1 signaling 0.6307271061209004 1.3439903571399514 0.1789515051308416 1.0 0.7103228267728395 8 Q86VP1 1 +Adp signalling through p2y purinoceptor 12 0.8785599140247166 1.3118632153886436 0.1895662908719972 1.0 0.7288644016668464 3 P04899,P63096 2 +Cobalamin cbl vitamin b12 transport and metabolism 0.6340708494947016 1.2993418659152185 0.1938266327001023 1.0 0.729576869328167 7 Q9NPF0,O14678 2 +Inflammasomes 0.6640106673709469 1.298714727191119 0.1940418480528949 1.0 0.729576869328167 6 P05067 1 +The nlrp3 inflammasome 0.6640106673709469 1.298714727191119 0.1940418480528949 1.0 0.729576869328167 6 P05067 1 +Defects in cobalamin b12 metabolism 0.6628147581936651 1.2935412980375638 0.1958239102669763 1.0 0.7343396635011612 6 Q9NPF0 1 +G2 m dna replication checkpoint 0.8718453608874603 1.2864816338087095 0.1982750245390891 1.0 0.7382576315027919 3 Q99640 1 +Rhog gtpase cycle 0.4477306563525525 1.281322918429664 0.2000802661331857 1.0 0.7382576315027919 41 Q86XL3,Q14126,Q14185,P29317,O15173,P51149,Q13190,P43121,P02786,P50402,Q8TAA9,P05556 12 +Endosomal sorting complex required for transport escrt 0.5562647386469985 1.2710179072348706 0.2037222781038834 1.0 0.7390139220759779 13 Q9UK41,Q9H9H4,Q9BRG1,Q92783,Q9Y3E7,O14964 6 +Transport and synthesis of paps 0.8656997045393586 1.2681948795001283 0.2047283651825986 1.0 0.7390139220759779 2 Q8TB61 1 +Antigen activates b cell receptor bcr leading to generation of second messengers 0.7229239451760123 1.2670404166451992 0.2051408386508506 1.0 0.7390139220759779 4 O43865,Q13586,P62993 3 +Epha mediated growth cone collapse 0.6007297665224198 1.2644576773855467 0.2060658022023263 1.0 0.7390139220759779 9 Q15375,P29317 2 +Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.4822477204070944 1.2626242056032242 0.2067242646370544 1.0 0.7390139220759779 24 P10619,P16278 2 +Rac2 gtpase cycle 0.4434308859057784 1.2526814594020383 0.2103216560673479 1.0 0.7390139220759779 43 Q86XL3,Q14126,Q9Y6W5,Q14185,P29317,O15173,P51149,P43121,P02786,O00459,P50402,Q8TAA9,Q9H0H5,P05556 14 +Neurotransmitter receptors and postsynaptic signal transmission 0.4443450732774403 1.2467875351132045 0.2124754121703576 1.0 0.7390139220759779 38 Q9BVA1,P17252,P08754,P22694,Q14168,P10644,Q12959,O14936,P04899,Q14012,P17612,P63096,O60266 13 +Transmission across chemical synapses 0.4401487643279761 1.240517419338228 0.2147840752883041 1.0 0.7390139220759779 46 Q9BVA1,P17252,P08754,P21964,Q96QD8,P22694,Q14168,P10644,Q12959,O14936,P04899,Q14012,P17612,P63096,O60266 15 +Rnd2 gtpase cycle 0.486832206077063 1.2362788977569603 0.2163549122470047 1.0 0.7390139220759779 22 O43396,P38159,Q9BTT6,Q07065,P29317,Q15058,P02786,O00459,Q8TAA9,Q9NNW5,Q9ULH0,Q9Y2I1 12 +Transcriptional regulation by e2f6 0.5480106689905611 1.2265991032271395 0.21997330643309 1.0 0.7390139220759779 13 Q9H9B1,Q96KQ7 2 +Netrin 1 signaling 0.5478433698114913 1.2256975452188958 0.2203125143334632 1.0 0.7390139220759779 13 O94813,Q9Y6N7 2 +Phase i functionalization of compounds 0.516068220340554 1.2246437171906104 0.2207094886908065 1.0 0.7390139220759779 16 O43169 1 +Ca2 pathway 0.6670777856377318 1.2236830733057815 0.2210718074702042 1.0 0.7390139220759779 5 P17252,P09471 2 +Wnt mediated activation of dvl 0.8526233958940315 1.213966694278248 0.2247604426867613 1.0 0.7390139220759779 3 P67870 1 +Cation coupled chloride cotransporters 0.8493150684931496 1.2018091808467055 0.2294374676083788 1.0 0.7390139220759779 2 P55011 1 +Regulated necrosis 0.4976983050427035 1.1979760035336384 0.2309263590514438 1.0 0.7390139220759779 19 O75955,Q14254,O00560,P41440 4 +Thromboxane signalling through tp receptor 0.847393874261148 1.1942861910200782 0.2323660374267953 1.0 0.7390139220759779 3 Q14344,Q13685 2 +Reactions specific to the complex n glycan synthesis pathway 0.8468565287479821 1.1922653501878862 0.2331572163528064 1.0 0.7390139220759779 3 P04066,Q16706 2 +Sars cov 1 infection 0.5312472867168065 1.1891919699062572 0.2343641337045727 1.0 0.7390139220759779 14 P07711,Q9Y3E7 2 +Constitutive signaling by egfrviii 0.6386900655717267 1.1890455339680643 0.2344217493985505 1.0 0.7390139220759779 6 P00533 1 +Signaling by egfr in cancer 0.6386900655717267 1.1890455339680643 0.2344217493985505 1.0 0.7390139220759779 6 P00533 1 +Constitutive signaling by ligand responsive egfr cancer variants 0.6386900655717267 1.1890455339680643 0.2344217493985505 1.0 0.7390139220759779 6 P00533 1 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.5843466391752257 1.1862294398141775 0.2355317030465835 1.0 0.7390139220759779 9 Q14118,Q16850 2 +Interleukin receptor shc signaling 0.8444384739387407 1.183174912556895 0.2367398334189236 1.0 0.7390139220759779 3 P23458,O00459 2 +Glycogen breakdown glycogenolysis 0.5833804608984858 1.1816084328552745 0.2373611059267952 1.0 0.7390139220759779 9 P10253 1 +Shc1 events in egfr signaling 0.844211657265657 1.181204063076741 0.2375216675865015 1.0 0.7390139220759779 2 P00533 1 +Pi3k events in erbb2 signaling 0.844211657265657 1.181204063076741 0.2375216675865015 1.0 0.7390139220759779 2 P00533 1 +Grb2 events in erbb2 signaling 0.844211657265657 1.181204063076741 0.2375216675865015 1.0 0.7390139220759779 2 P00533 1 +Role of lat2 ntal lab on calcium mobilization 0.8442116572656425 1.1812040630766825 0.2375216675865248 1.0 0.7390139220759779 2 O00459 1 +Antigen processing cross presentation 0.424312051037401 1.1701778433565484 0.2419294073041711 1.0 0.746210834217411 54 Q9UBG0,Q9UIQ6,P07711,P04439,P10321 5 +Regulation of pten localization 0.837228041901701 1.1530724193808026 0.2488806610503284 1.0 0.7524872644918309 2 P46934 1 +Rnd3 gtpase cycle 0.4852583438840628 1.1517191517903385 0.2494364996886817 1.0 0.7524872644918309 20 O43396,P38159,P29317,Q8TAA9,O75976,Q9NNW5,Q14254,Q9Y2I1 8 +Hdl assembly 0.8358409457281011 1.1509010016297372 0.2497729656874634 1.0 0.7524872644918309 3 P17612,P22694 2 +Pka mediated phosphorylation of key metabolic factors 0.8358409457281011 1.1509010016297372 0.2497729656874634 1.0 0.7524872644918309 3 P17612,P22694 2 +Egfr transactivation by gastrin 0.835840945728101 1.150901001629736 0.2497729656874638 1.0 0.7524872644918309 3 P00533,P62993 2 +Platelet activation signaling and aggregation 0.4058838902526181 1.148880432851826 0.2506052871133115 1.0 0.7525337892790611 64 Q14344,P13473,P07602,Q8NCG7,P63096,Q08380,P05067,Q9UEU0,Q92520,Q9Y6I9,P04899,Q06481,P29992,P08754,Q13685,Q9NTK5,O00459,O60245,Q6YHK3,Q15833,O43852 21 +Flt3 signaling 0.6485223383426133 1.145556233691439 0.2519788151403177 1.0 0.7539986394533399 5 P31751 1 +The activation of arylsulfatases 0.835079237174338 1.1444327182185623 0.252444225891844 1.0 0.7539986394533399 2 P15289 1 +Regulation of tp53 activity through methylation 0.6281344650218355 1.1432850853639 0.2529202453745238 1.0 0.7539986394533399 6 Q96KQ7 1 +Rhoc gtpase cycle 0.4306444381990733 1.1348930991221804 0.2564201116893654 1.0 0.7577733826675962 35 P27105,P41440,Q07021,P43121,P02786,O75955,Q9H0H5,Q8TAA9,Q14254 9 +Activation of nmda receptors and postsynaptic events 0.4579644987624018 1.125012248397671 0.2605838440105481 1.0 0.7609261838422768 26 Q9BVA1,P17252,P22694,Q14168,P10644,Q12959,O14936,Q14012,P17612 9 +Regulation of tp53 activity through association with co factors 0.8281523771532532 1.1221094982975377 0.261815885842988 1.0 0.7619999274189985 3 Q8N9N5 1 +Interleukin 2 family signaling 0.6428340073376692 1.121627091766544 0.2620210276739012 1.0 0.7619999274189985 5 P23458,O00459 2 +Signaling by scf kit 0.5588379610203145 1.1154657883700514 0.2646508711268072 1.0 0.7663267005307742 10 P07947,O00459,P62993 3 +Elastic fibre formation 0.8254109692434091 1.111861519523058 0.2661976959738479 1.0 0.7663267005307742 3 P06756 1 +Molecules associated with elastic fibres 0.8254109692434091 1.111861519523058 0.2661976959738479 1.0 0.7663267005307742 3 P06756 1 +Signaling by insulin receptor 0.4919397775180472 1.105253929760895 0.2690495744785919 1.0 0.7696894952385547 17 Q93050,Q15904,P31751,O00459,Q9Y487 5 +Metabolism of porphyrins 0.5552236501654776 1.0976092529143535 0.2723751507033216 1.0 0.7729413052609938 10 P22830,Q7KZN9,P30519 3 +Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.6808934595304097 1.0965578527153543 0.2728347203833543 1.0 0.7729413052609938 4 O14786 1 +Rhou gtpase cycle 0.4705244810578822 1.0902627244403882 0.2755974301158301 1.0 0.7746081615681616 21 O43396,P62993,P29317,O00459,Q92783,Q8TAA9,Q9NNW5,O14964 8 +Synthesis of pips at the late endosome membrane 0.634630517795288 1.087149290361045 0.276970837315611 1.0 0.7769359117613105 5 Q9NYA4 1 +Insulin receptor recycling 0.5504792857068924 1.074160052752796 0.2827509530501979 1.0 0.7822296942237901 10 Q93050,Q15904 2 +Signal regulatory protein family interactions 0.8133457812667472 1.0668842464182404 0.2860241094405289 1.0 0.7822296942237901 3 Q08722 1 +Negative regulation of the pi3k akt network 0.4992562992389255 1.0644026937202782 0.287146314027324 1.0 0.7822296942237901 15 P00533,O00459,P31751,Q16537 4 +A tetrasaccharide linker sequence is required for gag synthesis 0.8133225893097086 1.0574531832456038 0.2903048103797305 1.0 0.7822296942237901 2 O94766 1 +Cd28 dependent pi3k akt signaling 0.8078989790435223 1.046653023898164 0.2952596370605391 1.0 0.7835102100768497 3 O00459,P31751 2 +Cell cell communication 0.4266565418752084 1.042902783849241 0.296993320182652 1.0 0.7849991786327069 33 P62993,Q96J84,Q9BY67,Q08722,O14936,O00459,Q92692,O60716,Q9Y624,P05556 10 +Darpp 32 events 0.5427124151424116 1.035756295656761 0.3003158515288593 1.0 0.7881217098133049 10 P10644,P17612,P22694 3 +Gab1 signalosome 0.6189557117392 1.021423159892005 0.307053997258595 1.0 0.7882062959312341 5 P00533 1 +Inla mediated entry of listeria monocytogenes into host cells 0.8039215686274475 1.0201940305735315 0.307636448154202 1.0 0.7882062959312341 2 O60716 1 +Triglyceride catabolism 0.5994865593197102 1.0192340513533156 0.3080918644446999 1.0 0.7882062959312341 6 P43304,P17612,P22694 3 +Assembly and cell surface presentation of nmda receptors 0.5376714496352268 1.0108265673019177 0.3120994451337338 1.0 0.7883196220135669 10 Q9BVA1,Q9BUF5,Q12959,Q14168,O14936 5 +Costimulation by the cd28 family 0.4893066163900174 1.0068699091987636 0.3139972939270032 1.0 0.7883196220135669 15 P62993,P31751,O00459,P07947,Q16537 5 +Glycogen metabolism 0.5066038832150404 1.0023277305355365 0.3161853336504943 1.0 0.7883196220135669 13 Q93100,P10253 2 +Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.5948506199801353 0.9992085519031232 0.3176936739698033 1.0 0.7883196220135669 6 P17612,P22694 2 +Downregulation of erbb2 signaling 0.5662931366916254 0.9924212180082804 0.3209920927677874 1.0 0.7883196220135669 7 Q9UNE7,P00533,P31751 3 +Signaling by notch3 0.5437183898615011 0.9915581288978588 0.3214131230806192 1.0 0.7883196220135669 9 P67809,Q92542 2 +Tie2 signaling 0.7915212424820257 0.9861428233445312 0.3240630320659892 1.0 0.7931704322592643 3 O00459 1 +Neurotransmitter clearance 0.7939833467633782 0.9810574093246868 0.3265644317877314 1.0 0.7939415520001597 2 P21964 1 +Signaling by kit in disease 0.608243978217224 0.9766686944105614 0.3287331984131811 1.0 0.7939415520001597 5 P07947,O00459 2 +Synthesis of pe 0.788493746692279 0.9750160887683712 0.329552279391591 1.0 0.7939415520001597 3 P35790 1 +Signaling by ptk6 0.4832374240950727 0.9717348482371522 0.3311824754422661 1.0 0.7939415520001597 15 Q14185,P00533,Q07666,P46108,Q8IZL8 5 +Signaling by erbb2 ecd mutants 0.5876039738800064 0.9679502460978264 0.333069218504378 1.0 0.7939415520001597 6 P00533,P62993 2 +Signaling by erbb2 in cancer 0.5876039738800064 0.9679502460978264 0.333069218504378 1.0 0.7939415520001597 6 P00533,P62993 2 +Activation of kainate receptors upon glutamate binding 0.7902229384904617 0.9663226485706912 0.333882756378951 1.0 0.7939415520001597 2 Q12959 1 +Nrcam interactions 0.7902229384904617 0.9663226485706912 0.333882756378951 1.0 0.7939415520001597 2 Q12959 1 +Ionotropic activity of kainate receptors 0.7902229384904617 0.9663226485706912 0.333882756378951 1.0 0.7939415520001597 2 Q12959 1 +Synthesis of pc 0.6010058453161313 0.9465236933513552 0.3438815433562454 1.0 0.7940045387140271 5 P35790 1 +Transport of small molecules 0.4972735721690612 0.9455244302960836 0.3443912044296191 1.0 0.7940045387140271 177 Q93050,Q8TEL6,P30519,Q8TB61,Q15904,Q96QD8,Q4KMQ2,P22694,Q8N4V1,Q9C0H2,Q9Y487,P55011,Q8WTV0,P35610,P98155,Q8IWT6,P35613,P61916,P33527,P51790,Q99436,P10644,Q9Y666,O60266,P38571,P11166,P51798,Q9NQ11,Q86WC4,P01130,P02792,Q04656,P98194,P02786,Q15043,P21796,Q99808,P27105,P45880,Q9H2J7,Q9Y277,P08195,P30825,P05026,Q9HD20,Q92581,O15118,Q9Y6M7 48 +Intraflagellar transport 0.4959063115115613 0.944174885515316 0.3450802868012657 1.0 0.7940045387140271 13 Q9BVA1,Q9BUF5,Q7Z4L5,Q92845,A0AVF1,Q92973 6 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.4938773791962748 0.933144796452068 0.3507452126433199 1.0 0.7940045387140271 13 P46379,P05067,Q13190,P50402 4 +Bicarbonate transporters 0.7816277195810032 0.9328081777224108 0.3509190181693884 1.0 0.7940045387140271 2 Q9Y6M7 1 +Eph ephrin signaling 0.4087310688060961 0.926112373720068 0.3543875841724113 1.0 0.7940045387140271 34 Q15375,Q92542,O00560 3 +Mitochondrial calcium ion transport 0.4611002790536954 0.9173351638236696 0.3589670363963853 1.0 0.7940045387140271 17 P21796 1 +Insulin receptor signalling cascade 0.54876198731174 0.9132445464497284 0.3611139401307528 1.0 0.7940045387140271 7 O00459,P31751 2 +Shc1 events in erbb2 signaling 0.6348629513461898 0.912180594958232 0.3616736572989103 1.0 0.7940045387140271 4 P00533,P62993 2 +Signaling by wnt in cancer 0.5256410625382789 0.9050145318165436 0.3654576886567819 1.0 0.7940045387140271 9 P56545,P35222,Q13363,Q16537 4 +Hemostasis 0.4542086298776987 0.8987866093935406 0.3687663339344038 1.0 0.7940045387140271 144 P14174,Q9BUF5,P42785,P22694,P13473,Q14344,P07602,P46108,Q8NCG7,Q08380,P63096,P05067,P07947,Q9UEU0,Q9Y624,Q8IWA4,P47756,P17301,P35613,P06756,Q9H4M9,P33176,Q07021,Q92520,Q9Y6I9,P10644,Q06481,P04899,P17612,P29992,Q16537,Q92896,Q9BVA1,P62993,P08754,Q08722,Q13685,Q9NTK5,O00459,Q9H0H5,O60245,P05556,Q02241,P17252,Q14185,Q9NSK0,Q9UNN8,P08195,P78310,Q6YHK3,Q15833,P05026,O43852 53 +Cd28 co stimulation 0.5224621195233786 0.8898252896258124 0.3735597049423893 1.0 0.7943007429352562 9 P07947,O00459,P31751,P62993 4 +Interleukin 12 signaling 0.4206644857657971 0.8871025531444238 0.3750236896156436 1.0 0.7943007429352562 28 P14174,P11233,O14979,P23458,P51809,P52597 6 +Signaling by egfr 0.4590800643108154 0.8846165847740636 0.3763634586998194 1.0 0.7943007429352562 16 Q96JA1,Q13685,P00533,Q92783,O14964 5 +Fatty acyl coa biosynthesis 0.4556739832782792 0.8841935191907462 0.3765917562238146 1.0 0.7943007429352562 17 Q9UMR5 1 +Ion homeostasis 0.4834426653028851 0.8764383658770969 0.3807917690122631 1.0 0.7943007429352562 13 P17252,Q12797,P54709,P17612,Q13586,P05026,O43865,P16615 8 +Heme biosynthesis 0.5657883931402924 0.8742971106966031 0.3819564724026998 1.0 0.7943007429352562 6 P22830 1 +Met promotes cell motility 0.5091332083012824 0.8698706468146223 0.3843710982600186 1.0 0.7943768558352283 10 P17301,P07942,P62993,P05556 4 +Neurotransmitter release cycle 0.5387633663842513 0.8682669534253467 0.3852482087298825 1.0 0.7943768558352283 7 Q96QD8 1 +Hdms demethylate histones 0.5147259986078168 0.8529160723791983 0.393705848045832 1.0 0.7943768558352283 9 Q8NB78 1 +E2f enabled inhibition of pre replication complex formation 0.5600316788149802 0.8497301349395875 0.3954751402691783 1.0 0.7943768558352283 6 Q9Y619 1 +Cdc42 gtpase cycle 0.39583744549783 0.8444759728745527 0.3984034842452038 1.0 0.7943768558352283 44 P27105,Q86VI3,Q6XZF7,Q9UQB8,P51149,O00161,P02786,Q14344,O00459,Q9Y4F1,A4D1P6,Q8TAA9,Q9H0H5 13 +Beta oxidation of pristanoyl coa 0.5585881883114348 0.8435815837027415 0.3989032589188577 1.0 0.7943768558352283 6 P43155 1 +Synthesis of pips at the golgi membrane 0.5031044333194276 0.8401898819219378 0.4008019305684591 1.0 0.7943768558352283 10 Q8TCG2 1 +Met activates ptk2 signaling 0.569891500136459 0.8181722771674174 0.41325882269311 1.0 0.7943768558352283 5 P17301,P05556 2 +Interleukin 7 signaling 0.6104085971626234 0.8161696458672955 0.4144031149934091 1.0 0.7943768558352283 4 P23458 1 +Ire1alpha activates chaperones 0.4129253634236541 0.8143539584210859 0.4154422065753249 1.0 0.7943768558352283 27 O14773,Q13217,P43307,Q9NWM8,Q14554,O14653 6 +Signaling by notch1 0.4975492230044543 0.8128908472002879 0.4162806426415617 1.0 0.7943768558352283 10 Q92542 1 +Heme degradation 0.6089009084576893 0.8103113955222464 0.4177612275396165 1.0 0.7943768558352283 4 P30519 1 +Neurexins and neuroligins 0.5037592977959939 0.8007618839953721 0.4232695089920257 1.0 0.7943768558352283 9 Q14168 1 +Signaling by erbb2 0.4688885647649404 0.7974925366911789 0.425165035614693 1.0 0.7943768558352283 13 P62993,P17252,P31751,P00533,P07947 5 +Inositol phosphate metabolism 0.512051235404067 0.7928660591889226 0.4278558638526943 1.0 0.7943768558352283 8 Q96PE3,Q13572,Q9BW91,Q9UNW1 4 +Cell junction organization 0.4295804360806421 0.7912674577615513 0.4287879340686134 1.0 0.7943768558352283 20 Q9BY67,P19022,Q92692,O60716,P35222,Q9Y624,P05556 7 +Glycerophospholipid biosynthesis 0.3952012714521197 0.7910160572508246 0.4289346214014202 1.0 0.7943768558352283 33 Q9HCL2,Q8NCC3,Q8IV08,P35790 4 +Synthesis of pips at the plasma membrane 0.4414757185234186 0.7792310576090459 0.4358436181117988 1.0 0.7943768558352283 16 Q96T51,Q8TCG2,Q9BTU6,Q13614,O00459,Q96PE3 6 +Interleukin 12 family signaling 0.398771368548883 0.7757472218758724 0.4378982519991989 1.0 0.7943768558352283 31 P14174,P11233,O14979,P23458,P51809,P52597 6 +Pi3k akt signaling in cancer 0.4810706264570588 0.7756040334693878 0.4379828181094476 1.0 0.7943768558352283 11 P00533,O00459,P31751,P62993 4 +Phospholipid metabolism 0.3764797342752816 0.772471197249259 0.4398353996677602 1.0 0.7943768558352283 59 Q8IV08,P43304,Q8TCG2,Q9NYA4,Q9HCL2,Q8NCC3,P35790 7 +Interleukin 15 signaling 0.7320697285197394 0.772171357971745 0.4400129430804231 1.0 0.7943768558352283 3 P23458 1 +Arms mediated activation 0.732018360277574 0.7719914874609204 0.4401194692834673 1.0 0.7943768558352283 3 Q9ULH0 1 +Intra golgi and retrograde golgi to er traffic 0.3935857016224199 0.7686512874477937 0.4421003501497096 1.0 0.795373027658432 106 P33908,O00461,Q9BVK6,Q99747,Q16706,P53365,P33176,Q13190,O95249,P24390,O95721,P11717,O15260,P54920,Q10471,Q9P2W9,O43237,O43493,Q9H0H5,Q9H0U4,O43752,P20645,Q10472,P51151,Q02241,Q9NZ43,Q9NSK0 27 +Interferon signaling 0.3564477759584149 0.7529118723658867 0.4515028733090276 1.0 0.8004367732423324 70 P13591,P04439,P01889,P10321,P15260,P23458,P46934 7 +Sema3a pak dependent axon repulsion 0.5018045610477929 0.7459232453334395 0.4557137822911223 1.0 0.8004367732423324 8 O14786 1 +Fceri mediated ca 2 mobilization 0.5884271236819957 0.731609504408169 0.4644069454347812 1.0 0.8004367732423324 4 O43865 1 +Synthesis of pyrophosphates in the cytosol 0.727639000805803 0.7289275821315352 0.4660459617263393 1.0 0.8004367732423324 2 Q9BW91 1 +Metabolism of folate and pterines 0.4971224102481726 0.7245745302864125 0.4687130888211888 1.0 0.8008586949282902 8 Q9H2D1,P41440 2 +Metabolism of steroids 0.372314168443994 0.7193233357730213 0.4719417209027703 1.0 0.8030082322622677 58 Q99538,Q9BXW6,Q9UBM7,Q15392,O75845,P56937,O95772,Q15800,P04062,Q9H2C2,Q16850,Q9HCL2,P98164 13 +Disinhibition of snare formation 0.7230727907601491 0.7123305084732952 0.4762601362402312 1.0 0.8030082322622677 2 P17252 1 +Cholesterol biosynthesis 0.4091549309196135 0.7118749981945639 0.4765421855067671 1.0 0.8030082322622677 22 Q15392,O75845,P56937,Q15800,Q9H2C2,Q16850 6 +Transport of connexons to the plasma membrane 0.7146695325093986 0.7118688841238557 0.4765459719253424 1.0 0.8030082322622677 3 Q9BVA1,Q9BUF5 2 +Gap junction assembly 0.7146695325093986 0.7118688841238557 0.4765459719253424 1.0 0.8030082322622677 3 Q9BVA1,Q9BUF5 2 +Disassembly of the destruction complex and recruitment of axin to the membrane 0.4929640864582233 0.7056745320149928 0.4803905624869875 1.0 0.8063092479905267 8 P35222,O14641,Q16537 3 +Keratinization 0.5250447485637607 0.702377068475524 0.4824440422586029 1.0 0.8078528322191647 6 Q14574 1 +Formation of the cornified envelope 0.5250447485637607 0.702377068475524 0.4824440422586029 1.0 0.8078528322191647 6 Q14574 1 +Ptk6 regulates proteins involved in rna processing 0.6978601600909438 0.6549305184438895 0.5125124901349571 1.0 0.8289787723522292 3 Q07666 1 +Other interleukin signaling 0.6964184977055333 0.6501135819783729 0.5156188566409838 1.0 0.8303771848012338 3 P23458 1 +Listeria monocytogenes entry into host cells 0.4714838120485452 0.6490633036128743 0.5162974598398749 1.0 0.8303771848012338 9 O60716,Q92783,P62993,O14964 4 +Signalling to erks 0.4616109328437278 0.6381389109749479 0.5233832591748135 1.0 0.835333368858516 10 Q9ULH0,P62993,P11233 3 +Polo like kinase mediated events 0.5633053172122721 0.6376329838932026 0.523712619363959 1.0 0.835333368858516 4 Q99640 1 +Cardiac conduction 0.4322523884448266 0.6361970809420576 0.5246479755286819 1.0 0.835333368858516 14 P17252,Q12797,P54709,P17612,Q13586,P05026,O43865,P16615 8 +Constitutive signaling by aberrant pi3k in cancer 0.4850585805980496 0.6310445815940692 0.5280113750124198 1.0 0.836849019144473 7 P00533,O00459 2 +Fgfr2 alternative splicing 0.4138503168891053 0.629687653048532 0.5288989623121783 1.0 0.836849019144473 17 O15514,P31483,Q01085,P13984,P09651,P31943,P52597 7 +Nod1 2 signaling pathway 0.4758150959186658 0.6284310104810595 0.5297216277483914 1.0 0.836849019144473 8 Q96J02 1 +L1cam interactions 0.3700647011819702 0.6226841189965813 0.5334921207915024 1.0 0.8370235662203254 47 P17301,P06756,P13591,Q9BVA1,Q13740,Q12959,P00533,P67870,P07942,O00560,O14786,P05556 12 +Rac1 gtpase cycle 0.3652073930193579 0.6208211361877873 0.5347173148634936 1.0 0.8370235662203254 55 P05556,Q86VI3,Q9Y6W5,Q14185,P29317,Q9UQB8,P51149,O00161,P43121,Q14344,P02786,O00459,Q9Y4F1,P50402,Q8TAA9,Q9H0H5,Q9Y2I1 17 +Estrogen dependent nuclear events downstream of esr membrane signaling 0.5200591362170404 0.6193359253328784 0.5356950823810083 1.0 0.8370235662203254 5 P00533 1 +Signaling by met 0.389279679592815 0.605703111024629 0.5447119178004409 1.0 0.8407745832052179 23 P17301,Q96JA1,P62993,O14964,Q92783,P07942,P05556 7 +Dap12 signaling 0.5155601826910512 0.601970692916106 0.5471936457875213 1.0 0.8407745832052179 5 O00459 1 +Negative regulation of met activity 0.4608391048458069 0.5998798343990341 0.5485863226563623 1.0 0.8408617289606569 9 Q92783,Q96JA1,O14964 3 +Rhod gtpase cycle 0.3757103513397185 0.5961004806718764 0.5511081030920106 1.0 0.8408617289606569 31 Q9P2R3,O15173,P51149,P43121,O00459,P50402,Q8TAA9,Q9H0H5,Q9Y6M7 9 +Synthesis of pips at the er membrane 0.5514711346535618 0.5945694860713047 0.5521312819444719 1.0 0.8408617289606569 4 Q8TCG2 1 +Signaling by gpcr 0.3655531945381642 0.5924081348557765 0.5535773202673338 1.0 0.841504860726401 50 P22694,Q14344,P00533,P07602,Q8NCG7,P63096,P05067,O43865,P48960,P10644,P04899,O60266,P17612,P29992,P62993,P08754,O00459,P42892,P31751 19 +Rhof gtpase cycle 0.3911912057207355 0.5905752388501592 0.5548050596538836 1.0 0.841504860726401 22 P51149,O00161,P43121,Q9Y4F1,O00459,Q8TAA9,Q9Y6M7 7 +Constitutive signaling by akt1 e17k in cancer 0.5498859345595127 0.5888673768475631 0.5559502435762473 1.0 0.8419012721531907 4 P31751 1 +Metabolism of steroid hormones 0.4965750726996535 0.5860313397853998 0.5578544545402122 1.0 0.8420392628972388 6 Q53GQ0,O95772 2 +Crmps in sema3a signaling 0.4721454259420106 0.5757248749281921 0.5648011590882556 1.0 0.8479380606670726 7 O14786 1 +Translocation of slc2a4 glut4 to the plasma membrane 0.3649787469476888 0.5750854196801303 0.5652335282364993 1.0 0.8479380606670726 40 Q9UIQ6,Q9BVA1,P11233,P31751,O00161 5 +Attachment of gpi anchor to upar 0.505913978494628 0.565151898463611 0.5719704509410644 1.0 0.8508542657618928 5 O43292,Q9H490,Q969N2,Q96S52 4 +Slc transporter disorders 0.3607785134716348 0.5560727329358603 0.5781611344005131 1.0 0.8554570233550528 35 P35613,Q92581,P08195,P11166 4 +Free fatty acids regulate insulin secretion 0.6664531171217152 0.5526841799410426 0.5804796880505636 1.0 0.8554570233550528 3 P29992 1 +Negative regulation of nmda receptor mediated neuronal transmission 0.4663221242369521 0.5510843438635232 0.5815758573275129 1.0 0.8554570233550528 7 Q12959,Q14168,Q14012 3 +Constitutive signaling by overexpressed erbb2 0.5375442048928525 0.5450521938222745 0.5857176208866437 1.0 0.8578084375780753 4 P62993 1 +Transcriptional regulation by ventx 0.3983236008450493 0.5364792850524208 0.5916273487063943 1.0 0.8602744611291958 17 Q96KQ7 1 +Ptk6 regulates rho gtpases ras gtpase and map kinases 0.4963292974571526 0.5291754116886378 0.5966837719741274 1.0 0.8618148772249594 5 Q14185 1 +Interleukin 4 and interleukin 13 signaling 0.4180792221684376 0.5261267683298454 0.5988001311084115 1.0 0.8636540352525165 13 P23458,Q07820,P05556 3 +Tysnd1 cleaves peroxisomal proteins 0.4802586398333288 0.5213813316226604 0.6021011536351915 1.0 0.8649134515424878 6 Q2T9J0 1 +Calnexin calreticulin cycle 0.4490180252892065 0.5106629347834659 0.6095870989918877 1.0 0.8721502169311646 8 P14314,P30101,P27797,Q14697,Q9UBV2,Q13438,P27824 7 +Abc transporters in lipid homeostasis 0.6496507254164363 0.500578034703299 0.6166681243323306 1.0 0.8729870730533672 3 P56589,P40855 2 +Gap junction trafficking and regulation 0.4256257366823284 0.5003095046041469 0.6168571626381094 1.0 0.8729870730533672 11 Q9BVA1,Q9BUF5,P50570,Q07157,Q05193,P09496 6 +Cargo concentration in the er 0.401049786061928 0.5002332267027397 0.6169108649577129 1.0 0.8729870730533672 15 Q96PC5,P53634 2 +Egfr downregulation 0.4285376400057299 0.482183584998271 0.6296755366832274 1.0 0.8796937644839207 10 P00533,Q92783,O14964 3 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.4140653138298762 0.478642987067759 0.6321926315420243 1.0 0.8822713768022947 12 O60725,P63241,P15289,O43681 4 +Metabolism of cofactors 0.4486929465096024 0.4778473739585391 0.632758840064523 1.0 0.8822713768022947 7 Q86YH6,O75874,Q5T2R2,P00374 4 +Thrombin signalling through proteinase activated receptors pars 0.512689258349514 0.4602970646090813 0.6453030078638688 1.0 0.8893199092901481 4 Q14344 1 +Myogenesis 0.4392337064791251 0.439512007469341 0.6602905834898387 1.0 0.9029885618742995 7 P19022,Q92859 2 +Apoptotic cleavage of cell adhesion proteins 0.469281016668934 0.4314503726764729 0.6661409299495888 1.0 0.9075441373061852 5 Q16625 1 +Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.5036991926578583 0.430937081003151 0.6665141203965346 1.0 0.9075441373061852 4 O00459 1 +Biological oxidations 0.346502770794864 0.412131256434094 0.680243220038911 1.0 0.9162066054399322 48 Q9UJ14,Q8TB61,O43169,Q9NX62,Q16850 5 +Wax and plasmalogen biosynthesis 0.4958335564872695 0.4058742851993875 0.6848349731631886 1.0 0.9200318703364356 4 O00116 1 +Raf activation 0.4116836116269481 0.4055637336493742 0.6850631805020924 1.0 0.9200318703364356 10 Q16537 1 +Inlb mediated entry of listeria monocytogenes into host cell 0.4288506784203523 0.3983216626971327 0.6903930942593 1.0 0.9200318703364356 7 Q92783,O14964 2 +Intrinsic pathway for apoptosis 0.3651785610214503 0.3971868822482394 0.6912296547615449 1.0 0.9200318703364356 21 Q07021,Q9NR28 2 +Downstream signal transduction 0.4219715908372954 0.3968520237547435 0.6914765846528579 1.0 0.9200318703364356 8 O00459,P62993 2 +Signaling by pdgf 0.4219715908372954 0.3968520237547435 0.6914765846528579 1.0 0.9200318703364356 8 O00459,P62993 2 +Gpvi mediated activation cascade 0.4409787577306001 0.3740441678431668 0.7083714560739722 1.0 0.9303496082077516 6 P60953,P16885,Q06124,O00459,P84095 5 +Transport to the golgi and subsequent modification 0.3263234588698793 0.3588680754757646 0.7196937830415073 1.0 0.936587799848537 83 P33908,Q9BVK6,Q5SRI9,Q96PC5,Q99747,Q16706,P53634,O43237,Q13190,P04066,O60512,O95249,Q12893,P24390,P54920,Q10469,Q9H0U4 17 +Defective intrinsic pathway for apoptosis 0.3749228412689289 0.3570041158565527 0.7210887245002913 1.0 0.9370444545578162 15 P05067 1 +Signaling by pdgfr in disease 0.4352176868001285 0.3536363144053839 0.7236114557652082 1.0 0.9391132281105844 6 O00459 1 +Wnt ligand biogenesis and trafficking 0.4329120731379336 0.3455676669368158 0.7296676486064655 1.0 0.9433085747916112 6 O60493,Q9Y3A6,Q5T9L3,Q96QK1,Q9UBQ0 5 +Apoptotic factor mediated response 0.4149780685614876 0.344920770130849 0.7301539354351911 1.0 0.9433085747916112 7 Q07021 1 +Glutathione synthesis and recycling 0.4136683626887439 0.3399841098029894 0.7338684944596356 1.0 0.9463914973800732 7 Q9UJ14 1 +Signaling by ntrk2 trkb 0.4408602150537607 0.3360933629897946 0.7368004631842711 1.0 0.9466956255574568 5 Q00535,P19174,P62993,Q06124 4 +Rhov gtpase cycle 0.3638713202298599 0.3354253352105442 0.7373042590808674 1.0 0.9466956255574568 17 O43396,P29317,Q8TAA9 3 +Prolonged erk activation events 0.4124113137068377 0.3352638427677347 0.7374260662237031 1.0 0.9466956255574568 7 Q9ULH0 1 +Signaling by fgfr 0.3474768600558039 0.3248180818545245 0.7453187586309653 1.0 0.9499814231208636 24 O15514,P31483,P62993,Q01085,P13984,P09651,P31943,P52597 8 +Signaling by fgfr2 0.3474768600558039 0.3248180818545245 0.7453187586309653 1.0 0.9499814231208636 24 O15514,P31483,P62993,Q01085,P13984,P09651,P31943,P52597 8 +Cd209 dc sign signaling 0.4258249519798496 0.3211338333859815 0.7481089717163751 1.0 0.9518341441478924 6 P17612,P22694 2 +Pi metabolism 0.3448038784288786 0.3202534689662863 0.7487761933963419 1.0 0.9518341441478924 27 Q9NYA4,Q9BTU6,Q8TCG2,O00459 4 +Pregnenolone biosynthesis 0.4659607030878112 0.3165782629510096 0.7515636316891845 1.0 0.9528275579689394 4 O95772 1 +Ros and rns production in phagocytes 0.3948459227311782 0.3119526661921177 0.7550764963397405 1.0 0.9538865312802572 9 Q93050 1 +Activation of bh3 only proteins 0.3834141087776055 0.3041869935381215 0.760985433290728 1.0 0.9582346905938391 11 Q9Y3B8,P63104,P31946,P31751,P62258,P63167,P27348,Q04917,P04637,Q96FJ2 10 +Signaling by erythropoietin 0.4584789035205632 0.2958083307260415 0.767376460574063 1.0 0.9609063763779202 4 P16885,P46109,P62993 3 +Synthesis of ip3 and ip4 in the cytosol 0.458478903520552 0.2958083307260107 0.7673764605740865 1.0 0.9609063763779202 4 P16885,Q01968,Q13572 3 +Transport of vitamins nucleosides and related molecules 0.3890332660289578 0.2885779788736438 0.7729043491824463 1.0 0.9645656145643317 9 Q8TB61 1 +Synthesis of pa 0.3846709595965831 0.2884448141492263 0.7730062679526082 1.0 0.9645656145643317 10 Q9HCL2 1 +Pyruvate metabolism 0.3546018871435037 0.2833542004615315 0.7769053329585733 1.0 0.9685827641871976 17 P21796 1 +Activation of ampk downstream of nmdars 0.4135274634160368 0.2801303756458537 0.7793774808782112 1.0 0.970367732553002 6 P68371,Q9BVA1,Q9BUF5 3 +Ras activation upon ca2 influx through nmda receptor 0.4097824834543579 0.2680151380707382 0.7886876663885916 1.0 0.9738994147346126 6 Q12959,Q14168 2 +Long term potentiation 0.4097824834543579 0.2680151380707382 0.7886876663885916 1.0 0.9738994147346126 6 Q12959,Q14168 2 +Unblocking of nmda receptors glutamate binding and activation 0.4097824834543579 0.2680151380707382 0.7886876663885916 1.0 0.9738994147346126 6 Q12959,Q14168 2 +Plasma lipoprotein remodeling 0.5699704539349901 0.2555917539552471 0.798266086351525 1.0 0.9755824811757488 2 Q9BU23 1 +Rho gtpases activate iqgaps 0.3705865212079559 0.248407613660554 0.8038190433183201 1.0 0.9779388015701036 11 P35222,Q9BVA1,Q9BUF5,Q86VI3 4 +Activation of irf3 irf7 mediated by tbk1 ikk epsilon 0.5648670427074844 0.2447546378562167 0.8066464194613792 1.0 0.9791065994314014 2 Q06124 1 +Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.5462809749841595 0.2338533980078267 0.8150987930771973 1.0 0.983164701717478 3 P18887 1 +Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.333363029591295 0.2333247421094411 0.8155092473193397 1.0 0.983164701717478 25 O14979,P14174,P11233,P52597 4 +Atf6 atf6 alpha activates chaperone genes 0.5576148267526109 0.2299321090561681 0.818144525272559 1.0 0.983844682289786 2 P27797 1 +Atf6 atf6 alpha activates chaperones 0.5576148267526109 0.2299321090561681 0.818144525272559 1.0 0.983844682289786 2 P27797 1 +Pyruvate metabolism and citric acid tca cycle 0.3212974688367757 0.2262496477383821 0.8210072582420476 1.0 0.9864547580058328 36 Q13423,P21796,P48735 3 +Signalling to ras 0.5382724201597988 0.2178165081871408 0.8275720816936958 1.0 0.989157277780612 3 P11233 1 +Vegfr2 mediated vascular permeability 0.3653238682414016 0.2100518574029018 0.8336271993949653 1.0 0.9925663324948264 10 O60716,P31751,P42345 3 +Signaling by tgf beta receptor complex 0.3342262988386955 0.2054756197788811 0.8372005443094344 1.0 0.9941756463674534 21 Q9Y624 1 +E2f mediated regulation of dna replication 0.3580435619590066 0.1960905237500536 0.8445393132295476 1.0 0.998729063362743 11 Q9Y619 1 +Gastrin creb signalling pathway via pkc and mapk 0.3686024593714891 0.1832957263362035 0.8545659874834208 1.0 1.0 7 P00533,P62993 2 +Signaling by csf3 g csf 0.3683000734580837 0.1823418131155456 0.8553144865546871 1.0 1.0 7 P23458 1 +Nephrin family interactions 0.3536005139838361 0.1781420985958262 0.8586113808624709 1.0 1.0 11 O14936,Q96J84 2 +Vegfr2 mediated cell proliferation 0.4096209222746418 0.1780950310138362 0.8586483443284654 1.0 1.0 4 O43865 1 +Signaling by hippo 0.362861961294637 0.1754039399233898 0.8607622449696002 1.0 1.0 8 O14641,Q13188,Q07157 3 +Citric acid cycle tca cycle 0.3325032246663276 0.1753724799616262 0.8607869632685485 1.0 1.0 19 Q13423 1 +Pre notch processing in golgi 0.3800263388606495 0.165229553231362 0.8687633048318513 1.0 1.0 5 Q04721 1 +Sealing of the nuclear envelope ne by escrt iii 0.3536801568074899 0.1563845310283395 0.8757299296082646 1.0 1.0 9 Q9Y3E7,Q9BVA1 2 +Signaling by tgfb family members 0.3237959201249607 0.1559202708061901 0.8760958669316143 1.0 1.0 22 Q9Y624 1 +P75ntr negatively regulates cell cycle via sc1 0.5073865162503334 0.1460412512113769 0.8838888237521298 1.0 1.0 2 Q13547 1 +Degradation of cysteine and homocysteine 0.3670906379160023 0.1358322206000549 0.8919539187603902 1.0 1.0 5 Q96SZ5 1 +Signaling by mras complex mutants 0.4990598979317628 0.1352518278553791 0.8924127708135283 1.0 1.0 2 P10398 1 +Aryl hydrocarbon receptor signalling 0.4841483073616262 0.12904041942654 0.8973256660991793 1.0 1.0 3 Q15185,O00170 2 +Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.3469994079362449 0.1245801162634435 0.9008559706676768 1.0 1.0 8 P14635 1 +Carboxyterminal post translational modifications of tubulin 0.3582845649212406 0.117338710988609 0.9065916499627588 1.0 1.0 5 Q9BVA1 1 +Copi dependent golgi to er retrograde traffic 0.3127951147183894 0.1168696689218385 0.9069633341005724 1.0 1.0 53 Q9BVK6,Q99747,Q9P2W9,P33176,P24390,Q9H0H5,Q02241,O15260,Q9NZ43,P54920,Q9NSK0,Q9H0U4 12 +Telomere c strand synthesis initiation 0.3730180059123853 0.1120254665520894 0.910803214275792 1.0 1.0 4 P49643,P49642,Q9NYB0 3 +Signaling by fgfr3 0.3418504572350743 0.1047446967122203 0.916578394164384 1.0 1.0 7 P19174,P30153,P62993,Q06124,P28482,P22681 6 +Signaling by fgfr4 0.3418504572350743 0.1047446967122203 0.916578394164384 1.0 1.0 7 P19174,P30153,P62993,Q06124,P28482,P22681 6 +Signaling by fgfr1 0.3418504572350743 0.1047446967122203 0.916578394164384 1.0 1.0 7 P19174,P30153,P62993,Q06124,P28482,P22681 6 +Er quality control compartment erqc 0.4639186733703402 0.1045396381786182 0.9167411138698396 1.0 1.0 3 Q13438 1 +Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.4591617409994518 0.0994327826005481 0.9207946549767824 1.0 1.0 3 P35270,P00374 2 +Acetylcholine regulates insulin secretion 0.4544221951205256 0.0945845590644741 0.9246448149260764 1.0 1.0 3 P29992 1 +Erythropoietin activates phospholipase c gamma plcg 0.4582326081117376 0.0941025166633922 0.9250277212466356 1.0 1.0 2 P16885 1 +Uptake and function of anthrax toxins 0.4547408004297646 0.0914183224426749 0.9271602035054556 1.0 1.0 2 Q8WUM4 1 +Fcgamma receptor fcgr dependent phagocytosis 0.3056527870577924 0.0897365265973177 0.9284965889950536 1.0 1.0 38 Q8IV08,P62993,Q9Y6W5,Q14185,Q9UQB8,O00459,P07947,O43865 8 +Pi5p regulates tp53 acetylation 0.4442653773838168 0.0840722994892497 0.932998948458106 1.0 1.0 2 Q8TBX8 1 +Negative regulation of fgfr4 signaling 0.3417585372411921 0.083624480321379 0.9333550026239754 1.0 1.0 6 P30153,P62993,Q06124,P28482,P22681 5 +Negative regulation of fgfr2 signaling 0.3417585372411921 0.083624480321379 0.9333550026239754 1.0 1.0 6 P30153,P62993,Q06124,P28482,P22681 5 +Spry regulation of fgf signaling 0.3417585372411921 0.083624480321379 0.9333550026239754 1.0 1.0 6 P30153,P62993,Q06124,P28482,P22681 5 +Negative regulation of fgfr1 signaling 0.3417585372411921 0.083624480321379 0.9333550026239754 1.0 1.0 6 P30153,P62993,Q06124,P28482,P22681 5 +Negative regulation of fgfr3 signaling 0.3417585372411921 0.083624480321379 0.9333550026239754 1.0 1.0 6 P30153,P62993,Q06124,P28482,P22681 5 +Signaling by mapk mutants 0.4429223744292244 0.083204359111735 0.9336890466909676 1.0 1.0 2 Q99956 1 +Transcriptional regulation of pluripotent stem cells 0.4426537738383012 0.0830327240411493 0.9338255194245062 1.0 1.0 2 Q99626 1 +Interleukin 23 signaling 0.442653773838292 0.0830327240411434 0.9338255194245108 1.0 1.0 2 P07237 1 +Signaling by leptin 0.4426537738382893 0.0830327240411417 0.9338255194245122 1.0 1.0 2 Q06124 1 +Sensory processing of sound 0.31440182214826 0.0780969223090023 0.937750955360521 1.0 1.0 19 Q00013,O14936,P47756,P56545 4 +Rhobtb3 atpase cycle 0.3359165440772939 0.0759959966074722 0.9394222832333884 1.0 1.0 5 P51151 1 +Traf6 mediated induction of tak1 complex within tlr4 complex 0.4306824288017081 0.0737408668302491 0.941216580262112 1.0 1.0 3 Q15750,Q6SZW1 2 +Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 0.4290703922622143 0.0725234316958966 0.9421853587684188 1.0 1.0 3 P12814,P49023 2 +Kinesins 0.3093574213921135 0.0628604704057066 0.9498776126073436 1.0 1.0 21 Q9BVA1,Q9BUF5,P33176,Q02241,Q9H0H5,Q9NSK0 6 +Ncam signaling for neurite out growth 0.3250116947965753 0.0617813149756682 0.9507369835479216 1.0 1.0 7 P13591 1 +Synthesis of wybutosine at g37 of trna phe 0.3886650550631199 0.0597627012099547 0.9523446325762212 1.0 1.0 2 O60294 1 +P75ntr regulates axonogenesis 0.3690572119258705 0.0555528410975925 0.9556980338009547 1.0 1.0 2 Q9NQC3 1 +Metalloprotease dubs 0.3221635306073952 0.0550375390622457 0.9561085572549533 1.0 1.0 7 Q9NXR7,Q92783 2 +Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.3257188927707537 0.0548180856567869 0.9562833917960514 1.0 1.0 4 P22307,O14734,P51659 3 +Cytosolic iron sulfur cluster assembly 0.315492200107587 0.0398464825943251 0.9682155178852964 1.0 1.0 7 O75027,Q96T76,Q6FI81,P18074,P28340,Q9Y5Y2 6 +Ubiquinol biosynthesis 0.3594841483073517 0.0393506765078353 0.9686108038676928 1.0 1.0 3 Q86YH6,Q5T2R2 2 +Budding and maturation of hiv virion 0.3154855285914744 0.0389369661279355 0.9689406441962196 1.0 1.0 11 Q9UK41,Q9H9H4,Q9Y3E7 3 +Mtorc1 mediated signalling 0.3160927806397786 0.038647995431536 0.9691710360340312 1.0 1.0 8 P06730,P23588,Q9Y2Q5,P42345 4 +Response of eif2ak1 hri to heme deficiency 0.3422890918860756 0.0355892409726232 0.9716098873484597 1.0 1.0 3 P05198,P08243 2 +Signal attenuation 0.3414830736163259 0.0354427996788954 0.971726656926601 1.0 1.0 3 P28482,P62993 2 +Ngf stimulated transcription 0.3318108543793578 0.0338675692999914 0.9729827542942876 1.0 1.0 3 Q00535,P50570 2 +Apobec3g mediated resistance to hiv 1 infection 0.3277807630306203 0.0333032252234202 0.9734327818316236 1.0 1.0 3 O75475,O75531 2 +Diseases of mismatch repair mmr 0.3036002149381971 0.0308395320380509 0.975397513395033 1.0 1.0 3 P20585,P52701 2 +Rho gtpases activate ktn1 0.3111929222261541 0.0267320858781774 0.9786734214411924 1.0 1.0 8 Q9NSK0 1 +Maturation of sars cov 2 nucleoprotein 0.2989247311827882 0.0251132138949249 0.9799646603429032 1.0 1.0 5 P49840,P48729,P78362,Q96SB4 4 +Interleukin 37 signaling 0.2356893308250459 0.0128440411908715 0.9897522195979496 1.0 1.0 4 Q06124,P40763,Q9H3S7 3 +Platelet aggregation plug formation 0.2844905040665215 0.0107929411071533 0.9913886461112316 1.0 1.0 5 P62993 1 +Integrin signaling 0.2844905040665215 0.0107929411071533 0.9913886461112316 1.0 1.0 5 P62993 1 +Condensation of prophase chromosomes 0.3053273124420722 0.0069013647742944 0.9944935513091132 1.0 1.0 11 P14635,Q9UPP1 2 +Sars cov 2 infection 0.2973915660360626 0.0059354350451563 0.9952642358221844 1.0 1.0 26 P07711,Q9Y3E7,Q16706,Q10472 4 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7fa004f4731faedf36dcccfe15deb2a86d2306d3 --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine neurotransmitter release cycle", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase activating pathway", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "Butyrophilin btn family interactions", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate biosynthesis", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Clec7a inflammasome pathway", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen degradation", "Collagen formation", "Common pathway of fibrin clot formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of particulate exogenous antigens phagosomes", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Dectin 2 family", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective ext2 causes exostoses 2", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective lfng causes scdo3", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Electric transmission across gap junctions", "Elevation of cytosolic ca2 levels", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 activates ptk6 signaling", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythrocytes take up carbon dioxide and release oxygen", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acids bound to gpr40 ffar1 regulate insulin secretion", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose catabolism", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Il 6 type cytokine receptor ligand interactions", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 processing", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 2 signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Na cl dependent neurotransmitter transporters", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Ncam1 interactions", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of tcf dependent signaling by dvl interacting proteins", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotoxicity of clostridium toxins", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Norepinephrine neurotransmitter release cycle", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O glycosylation of tsr domain containing proteins", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Olfactory signaling pathway", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase 2 plateau phase", "Phase 3 rapid repolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by ntpdase proteins", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pou5f1 oct4 sox2 nanog repress genes related to differentiation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 promotes hif1a stabilization", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Ras signaling downstream of nf1 loss of function variants", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Reelin signalling pathway", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of keratinocytes", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "Runx3 regulates yap1 mediated transcription", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scavenging of heme from plasma", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Serotonin neurotransmitter release cycle", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sodium proton exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of immune response proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 24 hydroxycholesterol", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis of wybutosine at g37 of trna phe", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of cell cycle factors", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Toxicity of botulinum toxin type d botd", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trail signaling", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldl clearance", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Yap1 and wwtr1 taz stimulated gene expression", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc influx into cells by the slc39 gene family", "Zinc transporters"], "available_proteins": ["AAAS", "AAK1", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACE2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADAT3", "ADCY3", "ADD1", "ADD2", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALG9", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "APIP", "APLP2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARID4B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP5", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARV1", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATM", "ATP11C", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATRX", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BANP", "BAP1", "BARD1", "BASP1", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCKDHB", "BCKDK", "BCL10", "BCR", "BCS1L", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD4", "BRIP1", "BSG", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "CAB39", "CABIN1", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX4", "CBX5", "CCAR1", "CCAR2", "CCDC22", "CCNB1", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD109", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDK7", "CDK9", "CDKAL1", "CDKN2A", "CDS2", "CDX2", "CENPF", "CENPI", "CENPU", "CEP250", "CEP290", "CERS1", "CERS2", "CETN2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHUK", "CIAPIN1", "CIT", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLINT1", "CLNS1A", "CLTA", "CLTB", "CLTC", "CMAS", "CMBL", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT9", "COASY", "COG3", "COG4", "COG7", "COG8", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPE", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRAT", "CREG1", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CWC27", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DMD", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNASE2", "DNM1", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPM1", "DPY30", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DTX3L", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EGFR", "EGLN1", "EHD1", "EHHADH", "EHMT1", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENPP4", "ENTPD7", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERI1", "ERLEC1", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESD", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120B", "FAM3C", "FAM49B", "FAM91A1", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO21", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FIS1", "FKBP14", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNBP1", "FOXK1", "FOXK2", "FSCN1", "FTL", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "FYTTD1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALE", "GALK1", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GGT7", "GHDC", "GINS3", "GINS4", "GIT1", "GLA", "GLB1", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNL3", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILK", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INCENP", "INPP4A", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS7", "INTS8", "INTS9", "IPO5", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRS4", "ISCA2", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JAK1", "JUP", "KARS", "KAT5", "KAT7", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIAA1549", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFAP3", "KIFC1", "KIN", "KIRREL1", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LCMT2", "LDB1", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN2", "LMAN2L", "LMF2", "LMNA", "LMNB1", "LMO7", "LNPEP", "LONP2", "LPCAT1", "LPGAT1", "LRIG1", "LRP1", "LRP2", "LRPPRC", "LRR1", "LRRC1", "LRRC41", "LRRC8A", "LRRC8C", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LYPLA1", "LYPLA2", "LZTFL1", "M6PR", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MANEA", "MANF", "MAP2K1", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARC1", "MARC2", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED27", "MEN1", "METAP2", "MFAP1", "MFGE8", "MFN1", "MFN2", "MGA", "MGAT2", "MGRN1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMADHC", "MMGT1", "MMS19", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MPV17", "MRC2", "MRE11", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MVK", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1C", "MYO5A", "MYO6", "NAA35", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCOR1", "NCSTN", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEFL", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEO1", "NEU1", "NF1", "NF2", "NFRKB", "NFS1", "NHLRC2", "NHP2", "NID1", "NIP7", "NIPBL", "NISCH", "NIT2", "NLN", "NLRX1", "NME1", "NME2", "NME3", "NME4", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OBSL1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC1", "ORC2", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSTM1", "OTUB1", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK2", "PAN2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXK", "PEBP1", "PECR", "PELP1", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4K2B", "PI4KA", "PI4KB", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGO", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLXNA3", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "POFUT1", "POFUT2", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPID", "PPIE", "PPIH", "PPIL2", "PPIL3", "PPIL4", "PPME1", "PPOX", "PPP1CA", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKACB", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPN1", "PTPN11", "PTPN13", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PXMP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB31", "RAB32", "RAB33B", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RALA", "RALGAPB", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1CC1", "RBBP5", "RBBP6", "RBBP7", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RELA", "REPS1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOK2", "RIPK1", "RMI1", "RNASET2", "RNF14", "RNF20", "RNF213", "RNF31", "RNF40", "RNMT", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP7A", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SC5D", "SCAP", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEH1L", "SEL1L", "SELENOI", "SENP3", "SEPT2", "SEPT7", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGF29", "SGPL1", "SGSH", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A6", "SLIT2", "SLK", "SLTM", "SLU7", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMG1", "SMG6", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORD", "SORL1", "SORT1", "SPAG9", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3NL", "STARD7", "STAT1", "STAT3", "STIM1", "STIP1", "STK26", "STK3", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STT3A", "STUB1", "STX18", "STX5", "STX6", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SV2A", "SYDE1", "SYMPK", "SYNE1", "SYNE2", "TAB1", "TACC3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARS", "TARS2", "TAX1BP1", "TBC1D10B", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCP1", "TCTN3", "TDRKH", "TECR", "TERF2IP", "TEX10", "TEX2", "TEX264", "TFAM", "TFB1M", "TFG", "TFRC", "TGOLN2", "TGS1", "THADA", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM11", "TMEM115", "TMEM126B", "TMEM30A", "TMEM59", "TMEM87A", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMX3", "TNKS1BP1", "TNPO1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIO", "TRIP11", "TRIP12", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT5", "TRMT6", "TRMU", "TRPC4AP", "TRRAP", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSR1", "TSR3", "TST", "TSTA3", "TTC21B", "TTC26", "TTC37", "TTLL12", "TTLL4", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBIAD1", "UBQLN1", "UBR4", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USE1", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP32", "USP33", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAC14", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VLDLR", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "VTI1B", "WAPL", "WARS", "WASF2", "WASL", "WBP11", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR75", "WDR77", "WDR91", "WFS1", "WIPI2", "WLS", "WNK1", "WNK2", "WRN", "WTAP", "WWP2", "XAB2", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3HAV1", "ZCCHC11", "ZFYVE16", "ZMYM2", "ZNF131", "ZNF638", "ZNF830", "ZW10", "ZWILCH"], "leading_proteins": ["AAMP", "ABCB7", "ABCC1", "ABCD4", "ACOT8", "ACTN1", "ADCY3", "ADGRE5", "ADO", "AGPS", "AHCYL1", "AIP", "AKT2", "ALCAM", "ANKFY1", "ANKLE2", "ANO6", "APLP2", "APP", "ARAF", "ARFIP2", "ARSA", "ARV1", "ASAH1", "ASNA1", "ASNS", "ASPH", "ATG9A", "ATP13A1", "ATP13A2", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2C1", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP7A", "B3GAT3", "B4GALT3", "B4GAT1", "BABAM2", "BAG6", "BAIAP2", "BANF1", "BANP", "BSG", "C1QBP", "CADM1", "CALR", "CALU", "CAMK1", "CANT1", "CANX", "CAPZB", "CASK", "CBL", "CCNB1", "CD109", "CD320", "CD47", "CDC42", "CDH2", "CDK5", "CDX2", "CERS1", "CERS2", "CHKA", "CHMP3", "CHPF2", "CHST14", "CIAPIN1", "CKAP4", "CLCN3", "CLCN7", "CLTA", "COG3", "COLEC12", "COMT", "COX15", "CPD", "CRAT", "CREG1", "CRK", "CRKL", "CRTAP", "CSGALNACT2", "CSNK1A1", "CSNK2B", "CTBP1", "CTBP2", "CTNNB1", "CTNND1", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CXADR", "CYB5B", "CYP51A1", "DAG1", "DAGLB", "DHCR24", "DHCR7", "DHFR", "DIABLO", "DLG1", "DNAJC3", "DNASE2", "DNM1", "DNM2", "DNMBP", "DOCK1", "DSC3", "DSG2", "DUSP9", "DVL2", "DYNC1LI2", "DYNLL1", "DYNLL2", "ECE1", "EGFR", "EHD1", "EHMT1", "EHMT2", "EIF2S1", "EIF4B", "EIF4E", "EIF5A", "EMD", "ENPP4", "EPHA2", "EPHA7", "ERCC2", "F11R", "FAM3C", "FARP1", "FECH", "FKBP14", "FLOT1", "FLOT2", "FTL", "FUCA1", "FUCA2", "GAA", "GABARAPL2", "GALNS", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GBA", "GBE1", "GGH", "GGT7", "GLA", "GLB1", "GLG1", "GM2A", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNS", "GOLIM4", "GOLM1", "GOSR1", "GOSR2", "GPAA1", "GPAM", "GPD2", "GRB2", "GSK3A", "GTF2F2", "GUSB", "HDAC1", "HEXA", "HEXB", "HGS", "HLA-A", "HLA-B", "HLA-C", "HMOX2", "HNRNPA1", "HNRNPDL", "HNRNPF", "HNRNPH1", "HS2ST1", "HSD17B12", "HSD17B4", "HSD17B7", "ICMT", "IDH1", "IDH2", "IFNGR1", "IGF2R", "IMPAD1", "INPP4A", "IQGAP3", "IRS4", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPK1", "JAK1", "KDELR1", "KDM1B", "KDSR", "KHDRBS1", "KIDINS220", "KIF14", "KIF23", "KIF5B", "KIFAP3", "KIRREL1", "KLC4", "LAMB1", "LAMP1", "LAMP2", "LAMTOR2", "LCMT2", "LDLR", "LGALS3BP", "LGMN", "LIPA", "LMF2", "LNPEP", "LRIG1", "LRP1", "LRP2", "LRRC1", "LRRC8A", "M6PR", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MANEA", "MAPK1", "MCAM", "MCL1", "MFGE8", "MFN1", "MGAT2", "MIA2", "MIF", "MINPP1", "MMGT1", "MMS19", "MPP1", "MPP2", "MPP7", "MRC2", "MSH3", "MSH6", "MSMO1", "MTMR2", "MTMR4", "MTOR", "NAGLU", "NAPA", "NAPG", "NCAM1", "NCSTN", "NDC1", "NECTIN2", "NEDD4", "NEO1", "NEU1", 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0.0152248647419399 0.0879711233989737 +G protein signaling pathways 11 20 1.9878307856562996 0.0468304077002761 4.932038834951456 15.54611650485437 -0.4064088481494787 0.5464977370759283 3.1314630592896555 3.541064162635626 0.8414858696244415 0.3005316150817249 0.2647689707133314 1.0 1.0 0.4755559518983523 0.0139364810386785 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..bb5b37aeebcd98cc063c947cab7d5e841d673cde --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 617, + "title": "Average number of proteins per term", + "value": 11.917341977309562 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a128513672a2d7547de28f3019513861d6ab64c9 --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1b9399dc76e573b181d3683360df67fc69d955ca --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,208 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ebola virus infection in host 0.648177057585878 2.921689573411332 0.0034813833689395 0.883720821557999 0.4014771100532306 48 P17301,P06756,P07711,P04439,P07858,P01889,P10321,P61916,Q07021,Q08431,O15118,P00533,P41440,P46934 14 +Glycosaminoglycan degradation 0.9488835082055416 2.718066688853289 0.006566460162682 0.9828347187353306 0.4014771100532306 8 P16278,P34059,P54802,P06865,P07686,P15586,P08236 7 +Degradation pathway of sphingolipids including diseases 0.9361779338188992 2.667278277625564 0.0076468326776528 0.9912283250038348 0.4014771100532306 8 P16278,P06865,P07686,P06280,P17900,Q99519 6 +Ferroptosis 0.6700092066826449 2.5665420693812657 0.0102718164333868 0.998288671431016 0.4014771100532306 27 P02792,P45880,Q96QD8,P02786,Q13772,Q15043 6 +Sphingolipid metabolism in senescence 0.8260456718775455 2.5438101830779014 0.0109650653113566 0.9988893506824592 0.4014771100532306 12 Q96G23,P16278,Q13510,P04062,O15269,Q16739 6 +Sphingolipid metabolism overview 0.8852970560536623 2.541771715902357 0.0110292182633575 0.9989329238794492 0.4014771100532306 9 Q96G23,Q9NRA0,P27544,Q13510,O15269,Q16739,Q06136 7 +Sphingolipid metabolism integrated pathway 0.8852970560536623 2.541771715902357 0.0110292182633575 0.9989329238794492 0.4014771100532306 9 Q96G23,Q9NRA0,P27544,Q13510,O15269,Q16739,Q06136 7 +Sphingolipid pathway 0.8393233435396747 2.5130297966273907 0.0119699224497673 0.9994068122863988 0.4014771100532306 11 Q96G23,Q9NRA0,Q13510,P04062,O15269,Q16739,Q06136 7 +S1p receptor signal transduction 0.8148719135377538 2.2424854603664937 0.0249300139705583 0.9999998281769246 0.4755213220675755 9 P08754,Q9NRA0,P31751,Q13510,P04899,P63096 6 +Familial hyperlipidemia type 3 0.9596882558452 2.2103437361179212 0.0270813154200877 0.9999999560227956 0.4755213220675755 4 P01130,Q07954,P98155 3 +Calcium regulation in cardiac cells 0.6024237172999535 2.20108554654466 0.0277299682936071 0.9999999708581504 0.4755213220675755 29 P17252,P08754,P09471,P22694,P10644,P04899,Q14012,P17612,P63096,O60266,P0DP25,P29992,P05026 13 +Primary focal segmental glomerulosclerosis fsgs 0.6217314572668712 2.178842649537969 0.0293433594010148 0.9999999895409138 0.4764434934322674 24 Q14517,P06756,P07711,O00592,Q14118,Q14108 6 +Purinergic signaling 0.8787634408602178 2.095924311510468 0.0360889056911439 0.9999999998584806 0.5069509109565862 5 Q96RD7,P04899,P08754,P63096 4 +Metabolism of spingolipids in er and golgi apparatus 0.8690860215053855 2.0573840288038876 0.039649300207166 0.9999999999855714 0.5159707419833995 5 Q9NRA0,Q06136,Q16739,O95470 4 +Cholesterol biosynthesis with skeletal dysplasias 0.8007736893117584 2.0311749127159304 0.0422372543247335 0.99999999999727 0.5159707419833995 7 O75845,Q16850,Q15392 3 +7oxoc and 7betahc pathways 0.7322016669464153 2.024057736535404 0.0429642114898907 0.9999999999982911 0.5159707419833995 11 P61916,O15118,P34913,Q9UBM7 4 +Allograft rejection 0.7455758430698276 2.009244070359547 0.0445112560892209 0.9999999999993704 0.5159707419833995 10 P10321,P04439 2 +Vitamin b12 metabolism 0.7598393749463611 2.000654864234413 0.0454295966830415 0.999999999999652 0.5159707419833995 9 P01130,P98164 2 +G protein signaling pathways 0.6203856343728137 1.9878307856562991 0.0468304077002761 0.9999999999998594 0.5159707419833995 20 P08754,P09471,O43823,P22694,Q14344,P10644,P04899,O60266,P17612,P63096,P29992 11 +Statin inhibition of cholesterol production 0.8116820420591006 1.925038633850927 0.0542245251445669 0.9999999999999988 0.5530057179142406 6 P01130,Q07954 2 +Complement system 0.6669571122754354 1.9214644923140032 0.0546731747046493 0.9999999999999992 0.5530057179142406 14 P17301,P08754,Q07021,P04899,P07942,P17612,P98164 7 +Notch signaling 0.7380892923989536 1.9031473142293955 0.0570213256078844 0.9999999999999998 0.5584469507946775 9 Q04721,Q92542,P56545 3 +Network map of sarscov2 signaling pathway 0.5467686686452028 1.8864668422545936 0.0592320725407948 1.0 0.5622490578103144 31 P07711,P07858,Q07021,P23458,Q08380 5 +Hippo signaling regulation pathways 0.5615354044491371 1.794838714584524 0.0726794005910225 1.0 0.6406170023522985 24 P17252,P08754,P19022,P29317,P42345,P22694,P10644,P00533,P04899,P17612,P29992 11 +Immune response to tuberculosis 0.7683149619436542 1.7443446379347702 0.0810990123903727 1.0 0.6444236218201083 6 P15260 1 +Proteoglycan biosynthesis 0.7164716279998042 1.7346356600056023 0.0828053590557635 1.0 0.6444236218201083 8 Q8WVQ1,Q8TB61,Q8NCH0,Q9NX62 4 +Dopamine metabolism 0.8360655737704825 1.724881133386989 0.0845488962769349 1.0 0.6444236218201083 4 P21964,P17612,P22694 3 +Familial hyperlipidemia type 4 0.8292122910421084 1.6974149520365955 0.0896182377091268 1.0 0.6444236218201083 4 P01130 1 +Bile acids synthesis and enterohepatic circulation 0.8281472302470052 1.693142112692116 0.0904284199887088 1.0 0.6444236218201083 4 P01130 1 +Neural crest differentiation 0.6748864341744111 1.6794392816919734 0.093066463021316 1.0 0.6444236218201083 10 Q04721,P56545,O14641,P19022,P05556 5 +Oxidation by cytochrome p450 0.7522156356352983 1.676489511702946 0.0936423489057489 1.0 0.6444236218201083 6 O43169,Q16850 2 +Apoptosisrelated network due to altered notch3 in ovarian cancer 0.6070887679991533 1.6746638490798271 0.0940002041552832 1.0 0.6444236218201083 15 Q13501 1 +Hedgehog signaling pathway wp4249 0.7004170736029369 1.662480416896902 0.0964164866776564 1.0 0.6463927503263476 8 P98164,P17612,P22694 3 +Type ii interferon signaling ifng 0.6846805836699253 1.6592128330794906 0.0970729125479201 1.0 0.6463927503263476 9 P15260,P01889 2 +Spinal cord injury 0.5767074912285819 1.645692671210166 0.0998270486594083 1.0 0.655247755562287 18 P14174,Q08722,O94813,P00533,P08670 5 +Copper homeostasis 0.733598208727669 1.5975394871361663 0.1101455029847671 1.0 0.6738457463305652 6 P05067 1 +Sarscov2 and covid19 pathway 0.7224403373953054 1.5499919175686017 0.1211434559453001 1.0 0.6931070756603338 6 Q8WTV0,P07711 2 +Embryonic stem cell pluripotency pathways 0.5844611668863927 1.5492492183266215 0.12132182199565 1.0 0.6931070756603338 15 O14641,P62993,P31751,P42345,P23458,P00533,O00459 7 +Familial hyperlipidemia type 5 0.9377884661837396 1.5361470889920092 0.1245023094812036 1.0 0.6935173161492489 3 P01130 1 +Familial hyperlipidemia type 1 0.9377884661837396 1.5361470889920092 0.1245023094812036 1.0 0.6935173161492489 3 P01130 1 +Regulatory circuits of the stat3 signaling pathway 0.6402212561459548 1.5135004148844693 0.1301525958479541 1.0 0.6982969707668496 10 P23458,P15260 2 +Overview of interferonsmediated signaling pathway 0.7815227395799814 1.5050932266206944 0.1323001101829322 1.0 0.7005353851802013 4 P15260 1 +Complement system in neuronal development and plasticity 0.5856425151463817 1.488786108219574 0.1365437015693011 1.0 0.7005353851802013 14 Q5KU26,P06756,Q08431 3 +Inclusion body myositis 0.9232840822436243 1.4812225499100706 0.1385472790977397 1.0 0.7005353851802013 3 P05067 1 +Hippomerlin signaling dysregulation 0.5076794955705447 1.4750668657320405 0.1401945674960047 1.0 0.7005353851802013 26 P17301,P06756,P17252,P19022,P29317,P22694,P10644,P00533,P17612,P05556 10 +Head and neck squamous cell carcinoma 0.5351711419077543 1.4686649068019992 0.1419237004011753 1.0 0.7005353851802013 20 Q04721,Q14517,P31751,Q14145,P00533 5 +Mecp2 and associated rett syndrome 0.5203124385397933 1.4573659578765226 0.1450153887780119 1.0 0.7101150386986773 22 P35637,Q99640,Q00013,P67809,P31943,Q05086 6 +Wnt signaling pathway and pluripotency 0.5428878830176117 1.4435529971142862 0.148864754594481 1.0 0.7186455397264244 18 P01130,O14641,O60716,Q9H0H5,Q16537,P56545 6 +Nuclear receptors metapathway 0.4492610509215157 1.4427641576840198 0.1490869191004575 1.0 0.7186455397264244 57 P02792,P27105,Q13501,P29317,Q08431,Q9H2J7,P23786,P00533,Q9HCL2,Q15043 10 +Familial hyperlipidemia type 2 0.9000805801772875 1.4083175546122424 0.15903705983016 1.0 0.749052411566479 2 P01130 1 +Nephrotic syndrome 0.5567772610821272 1.393697438776253 0.1634089899943289 1.0 0.7627956650296653 15 O00592,Q14108 2 +Glucocorticoid receptor pathway 0.6370111734598243 1.373013117139266 0.169748268911094 1.0 0.767577886308188 8 P27105 1 +Vitamin d receptor pathway 0.5377417491734016 1.352338891977502 0.1762669281969562 1.0 0.7713240758689502 16 Q8IWT6,Q92783,Q96KA5,P48960 4 +Cannabinoid receptor signaling 0.629537021796577 1.3384884593052615 0.1807372599139034 1.0 0.7742587425928776 8 P10644,Q8NCG7,P17612,P22694 4 +Pi3kaktmtor signaling pathway and therapeutic opportunities 0.739332467507701 1.3337677359933526 0.1822799878890058 1.0 0.7742587425928776 4 Q8TDY2,O00459 2 +Hair follicle development cytodifferentiation part 3 of 3 0.6704710633811821 1.3266467406262905 0.1846255665590379 1.0 0.7742587425928776 6 Q04721,P00533,Q96JA1 3 +Metabolic pathway of ldl hdl and tg including diseases 0.8813925559739615 1.3225768178392974 0.1859761477523074 1.0 0.7742587425928776 3 P01130 1 +Tca cycle nutrient use and invasiveness of ovarian cancer 0.6901268127679345 1.3207239121556873 0.186593437941531 1.0 0.7742587425928776 5 P23458 1 +Myometrial relaxation and contraction pathways 0.4993712555038124 1.3195761068679963 0.1869765845159461 1.0 0.7742587425928776 22 P17252,P22694,P10644,O60266,P17612,P0DP25 6 +Autosomal recessive osteopetrosis pathways 0.8707223151577503 1.282238595467686 0.1997589609367012 1.0 0.8055639143656512 3 Q86WC4 1 +Selenium micronutrient network 0.5551579155531966 1.265068819260431 0.2058466591435725 1.0 0.8141499275101558 13 P01130 1 +Mitochondrial complex iv assembly 0.5859555701569513 1.2491074641978908 0.2116257709313365 1.0 0.8264120295230039 10 Q9Y2R0 1 +Il3 signaling pathway 0.5397000220148628 1.236172888222844 0.2163943061261628 1.0 0.8301878588020338 14 P23458,O00459,P62993,P17612 4 +Regulation of wnt bcatenin signaling by small molecule compounds 0.6690085554332172 1.2318149096048 0.21801823252513 1.0 0.8301878588020338 5 Q07954,P35222,O14641 3 +Metapathway biotransformation phase i and ii 0.476007946857894 1.219586731600571 0.2226215787870915 1.0 0.8301878588020338 24 Q86UY6,P21964,Q8NCH0,Q16850,Q7LGA3,P34913 6 +Neuroinflammation and glutamatergic signaling 0.4730671119499556 1.2150150732221336 0.2243603424918767 1.0 0.8301878588020338 25 Q8IWT6,P15260,Q96QD8,P23458,O60266,P17612,P11166 7 +Irinotecan pathway 0.8509266720386941 1.2083237956306834 0.226922738951794 1.0 0.8301878588020338 2 O15118 1 +Endothelin pathways 0.5887902573554881 1.207472385838358 0.2272502734269499 1.0 0.8301878588020338 9 P42892,P17252,P63096 3 +Thyroid stimulating hormone tsh signaling pathway 0.4750988791826529 1.1989794182100713 0.230535948690856 1.0 0.8330897988968599 23 P08754,P09471,P23458,O00459,P04899,O60266,P63096 7 +Folate metabolism 0.5208898959224126 1.1890387389792598 0.234424423152467 1.0 0.8360686074281627 15 P01130,Q8WTV0 2 +Congenital generalized lipodystrophy cgl 0.8442116572656531 1.181204063076726 0.2375216675865075 1.0 0.8414957141628007 2 P31751 1 +Vitamin d metabolism 0.8422340768589025 1.174892627955131 0.24003767535276 1.0 0.8414957141628007 3 P04062 1 +Nrf2 pathway 0.4624151118828744 1.1567565472780306 0.2473718394651567 1.0 0.8561662212731386 26 P02792,Q13501,P29317,Q9H2J7,Q15043 5 +Gpr143 in melanocytes and retinal pigment epithelium cells 0.8358409457281011 1.1509010016297372 0.2497729656874634 1.0 0.8561662212731386 3 P17612,P22694 2 +Arrhythmogenic right ventricular cardiomyopathy 0.4921453505499643 1.1333233846465238 0.25707847501381 1.0 0.8617077930683927 18 P17301,P06756,Q14118,P50402,P05556 5 +Ectoderm differentiation 0.4584201686922712 1.1282655076936017 0.2592078057572906 1.0 0.8617077930683927 26 O00592,P16278,O00560 3 +Notch signaling pathway 0.5095222777999869 1.1236397279140182 0.2611658951439051 1.0 0.8617077930683927 15 Q04721,Q96J02,Q92542 3 +Prostaglandin and leukotriene metabolism in senescence 0.6817414980989381 1.0999845111598228 0.2713388705053601 1.0 0.8811372794831958 4 O60266 1 +Serotonin htr1 group and fos pathway 0.5696351526381569 1.0600059247730398 0.2891419039243916 1.0 0.9091624804069388 8 P04899,P08754,P63096 3 +Mrna protein and metabolite inducation pathway by cyclosporin a 0.8073616335303572 1.044659843599997 0.2961802104781803 1.0 0.9091624804069388 3 Q14145,P08195 2 +Relationship between inflammation cox2 and egfr 0.619492153871891 1.023668345590023 0.3059919515279663 1.0 0.9091624804069388 5 P00533 1 +Osx and mirnas in tooth development 0.8039215686274693 1.020194030573616 0.3076364481541618 1.0 0.9091624804069388 2 Q04721 1 +Wnt signaling in kidney disease 0.8039215686274557 1.0201940305735635 0.3076364481541866 1.0 0.9091624804069388 2 O14641 1 +Hair follicle development organogenesis part 2 of 3 0.6584360596342343 1.0061475369914337 0.3143446044544267 1.0 0.9091624804069388 4 P13591,P05556 2 +Kallmann syndrome 0.6570322749844548 1.00052121837215 0.3170583344244733 1.0 0.9091624804069388 4 Q9Y2Y6 1 +Sudden infant death syndrome sids susceptibility pathways 0.4290289031002881 0.9882987369138324 0.3230063638432217 1.0 0.9091624804069388 30 P42892,P10644,P67809 3 +Neural crest cell migration in cancer 0.5428383243721111 0.9873402962944704 0.3234758423678552 1.0 0.9091624804069388 9 Q99523,Q9ULH0 2 +1q211 copy number variation syndrome 0.5217269222865717 0.9825769759261296 0.3258156807116688 1.0 0.9091624804069388 11 Q16625,Q9Y624 2 +Oligodendrocyte specification and differentiation leading to myelin components for cns 0.7942519473542997 0.9821114969701203 0.3260449220748085 1.0 0.9091624804069388 2 Q99640 1 +Small cell lung cancer 0.4672321498118403 0.9547743269511118 0.3396918330114622 1.0 0.910135877931945 17 P17301,P06756,P31751,O00459,P05556 5 +Phosphoinositides metabolism 0.5259125627284602 0.952688755582135 0.3407477922241155 1.0 0.910135877931945 10 Q9NYA4 1 +Extracellular vesiclemediated signaling in recipient cells 0.5767188701117962 0.9211241586293648 0.3569856085274518 1.0 0.9284066803545632 6 Q08431 1 +Ketogenesis and ketolysis 0.5502063876938635 0.919754530391901 0.3577010494048647 1.0 0.9284066803545632 7 P23786,P11166 2 +Splicing factor nova regulated synaptic proteins 0.4531300296218898 0.9160781131268696 0.3596259264258357 1.0 0.9284066803545632 19 Q9BY67,O14936,Q06481,Q92859 4 +Wnt signaling 0.4720200665253814 0.9067571307839988 0.3645352443590304 1.0 0.929173787663376 15 O14641,P17252,Q13363,P67870,Q8TAA9,P35222,P56545 7 +Pi3kakt signaling pathway 0.4015449840119867 0.9013777034339638 0.3673875321552133 1.0 0.929173787663376 46 P17301,P05556,P06756,P62993,P17252,P29317,P31751,P23458,P00533,O00459,P07942,Q07820,Q16537 13 +Development of ureteric collection system 0.5439343469018193 0.891507993973125 0.3726567049018841 1.0 0.9361579050851484 7 O94813,Q9Y6N7,Q5SZK8 3 +P53 transcriptional gene network 0.520148782587379 0.8787796711196333 0.3795207507379476 1.0 0.948033616215845 9 P04066 1 +Bladder cancer 0.5278433099895138 0.8656962849757642 0.386656737842225 1.0 0.9536212652495424 8 P00533 1 +Insulin signaling 0.3941342396182083 0.8624713930016158 0.388428168587037 1.0 0.9536212652495424 51 Q9H4M9,P62993,O14654,P17252,P41440,P33176,P22413,P31751,O00161,O75955,P10586,O00459,O95819,P46108,P11166,Q15833,Q96PE3,Q14254 18 +Triacylglyceride synthesis 0.5765891275958028 0.8455988602729075 0.3977765615776858 1.0 0.9536212652495424 5 Q9HCL2,O00116 2 +Autophagy 0.5030830720102183 0.8400848110531868 0.4008608357070635 1.0 0.9536212652495424 10 Q8TDY2,Q7Z3C6 2 +Malignant pleural mesothelioma 0.3658097357048424 0.8285937769276137 0.4073343105655604 1.0 0.9536212652495424 82 P23588,P19022,P23458,P00533,Q07820,P17301,P06756,P67870,P11166,P56545,O14641,P62993,Q14574,P29317,Q08722,O95819,P07942,Q99728,P05556,P31751,O00592,P08195,Q02241,Q8TDY2 24 +Hepatitis b infection 0.4144418785881575 0.8254771755794197 0.4091007356477041 1.0 0.9536212652495424 27 P62993,Q15904,P31751,P23458,O00459,Q9Y277,O00571 7 +Thyroid hormones production and peripheral downstream signaling effects 0.4474462297169909 0.8149442774561629 0.4151042068178459 1.0 0.9536212652495424 16 P06756,P62993,P17252,P42345,O60266,P17612 6 +Common pathways underlying drug addiction 0.5066753054464291 0.8146071625331036 0.4152972092516127 1.0 0.9536212652495424 9 P22694,P17612,P63096 3 +Ranklrank signaling pathway 0.440341441683864 0.8113054823114244 0.4171902624967738 1.0 0.9536212652495424 18 Q13501,P31751 2 +Oxysterols derived from cholesterol 0.504282198317498 0.803243324263661 0.4218341089113084 1.0 0.9536212652495424 9 P34913,Q9UBM7 2 +Hostpathogen interaction of human coronaviruses autophagy 0.5649153137504892 0.7978814462558844 0.424939291253926 1.0 0.9536212652495424 5 Q8TDY2 1 +Hippoyap signaling pathway 0.5624118081182747 0.7877030710510973 0.4308704088077457 1.0 0.9536212652495424 5 O95819,Q13188 2 +Camkk2 pathway 0.4501334249690863 0.7800948998800975 0.4353350182148168 1.0 0.9536212652495424 15 Q9Y3D6,Q13501,Q14012,O00429 4 +Dna damage response only atm dependent 0.4103611219610625 0.7603917131517461 0.4470204752262972 1.0 0.971167722586709 24 P01130,O14641,P31751,O00459,Q16537 5 +Acute viral myocarditis 0.4375179828759322 0.7555841854020608 0.4498985406560019 1.0 0.973990875735976 16 Q14118,P78310 2 +Focal adhesion pi3kaktmtorsignaling pathway 0.3822612332336132 0.7236674014238645 0.4692699508805811 1.0 0.9927063319013952 43 P17301,P05556,P06756,O14654,P29317,P31751,P23458,P00533,O00459,P11166,Q16537 11 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.4464107078060547 0.7146372887170729 0.4748331971980659 1.0 0.9927063319013952 14 O75844,P55209,P50402 3 +Insulin signaling in adipocytes normal condition 0.5810881967394165 0.7038304006773434 0.4815383990299069 1.0 0.9927063319013952 4 P31751 1 +Insulin signaling in adipocytes diabetic condition 0.5810881967394165 0.7038304006773434 0.4815383990299069 1.0 0.9927063319013952 4 P31751 1 +Glycerophospholipid biosynthetic pathway 0.4819837859382346 0.6980452665305356 0.485148885659914 1.0 0.9927063319013952 9 Q9HCL2,O15228,Q9BTU6,O00116 4 +Ncrnas involved in wnt signaling in hepatocellular carcinoma 0.463958636099584 0.6893462479884787 0.4906054007157836 1.0 0.9927063319013952 11 O14641,Q13363,P67870,P35222,P56545 5 +Nicotine effect on dopaminergic neurons 0.5364045786569245 0.6833518858683256 0.4943845151875701 1.0 0.9927063319013952 5 P17612,P63096 2 +Familial partial lipodystrophy fpld 0.4969366040383788 0.6826478705018679 0.4948293773126206 1.0 0.9927063319013952 7 O75844,P31751 2 +Angiopoietinlike protein 8 regulatory pathway 0.384139559381738 0.6808336482008632 0.4959767563393535 1.0 0.9927063319013952 32 O14654,P41440,P31751,O75955,O95819,P11166,Q14254 7 +Chemokine signaling pathway 0.3939151424203608 0.6749180677278641 0.4997278207713911 1.0 0.9927063319013952 27 P62993,P08754,P31751,P22694,O00459,P04899,O60266,P63096 8 +Erbb signaling pathway 0.4146755541106594 0.6719189566377789 0.5016352914982458 1.0 0.9927063319013952 19 P17252,P62993,P31751,P00533,O00459,P46108 6 +Kennedy pathway from sphingolipids 0.5313776200995977 0.6635186587406776 0.5069984334272175 1.0 0.9927063319013952 5 P35790,O95470 2 +Ras signaling 0.376341419893396 0.661326704478407 0.5084028193387056 1.0 0.9927063319013952 34 P11233,P62993,P29317,P31751,P22694,P00533,O00459,P17612,P0DP25,Q7Z569 10 +Alzheimers disease and mirna effects 0.3621809442828346 0.6597324218240889 0.5094255568065069 1.0 0.9927063319013952 90 P60900,Q9BUF5,P05067,P33176,Q99436,P67870,P0DP25,Q9BVA1,O14641,O14654,O00459,P21796,P49721,P45880,Q9P2E5,Q92542,P31751,Q9Y277,P07437,O00213,Q07954,Q8TDY2,Q9NSK0 23 +Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.5138002926990793 0.6559579518845721 0.511851179143247 1.0 0.9927063319013952 6 P06753,P00533 2 +Hepatitis c and hepatocellular carcinoma 0.4417677180768859 0.6192194310100073 0.5357718128414337 1.0 0.9927063319013952 12 O00592 1 +Intracellular trafficking proteins involved in cmt neuropathy 0.4476477427244778 0.608035892141806 0.5431636691696855 1.0 0.9934137806719804 11 O95140,Q13614,P51149,P20337 4 +Alzheimers disease 0.3527228085567789 0.5990152671979185 0.5491627037025575 1.0 0.9934137806719804 87 P60900,Q9BUF5,P05067,P33176,Q99436,P67870,P0DP25,Q9BVA1,O14641,O14654,O00459,P21796,P49721,P45880,Q92542,P31751,Q9Y277,P07437,O00213,Q07954,Q8TDY2,Q9NSK0 22 +Proximal tubule transport 0.4374155447114625 0.5968597866214845 0.5506009975514066 1.0 0.9934137806719804 12 P08183,P36543,P08195,P11166,P05026 5 +Genes controlling nephrogenesis 0.4599430308722484 0.5957641884214187 0.551332770595188 1.0 0.9934137806719804 9 Q04721,O94813,P05556 3 +Influence of laminopathies on wnt signaling 0.441716064774581 0.5435658488001311 0.586740266009568 1.0 1.0 10 O75844,P50402 2 +Synaptic signaling pathways associated with autism spectrum disorder 0.4316462275032547 0.5294776311189562 0.5964741577726107 1.0 1.0 11 Q05086,O00459,P31751,P42345 4 +Wnt signaling pathway 0.4184404537860237 0.5280159004490013 0.5974882999767797 1.0 1.0 13 O14641,P17252,Q13363,Q9BTU6,P42345,P35222 6 +Il7 signaling pathway 0.4602076667331023 0.5254401706842939 0.5992772343737398 1.0 1.0 7 P23458 1 +Pdgfrbeta pathway 0.4349046806387318 0.4826402495784007 0.6293511951184418 1.0 1.0 9 P23458,P62993 2 +Mthfr deficiency 0.4416578060002751 0.4791139086631586 0.6318575955475119 1.0 1.0 8 Q9H9B1,P35790,Q96KQ7 3 +Endochondral ossification with skeletal dysplasias 0.4273347663175035 0.4766404456896213 0.6336181773688634 1.0 1.0 10 P22413,Q96QD8,P17612 3 +Endochondral ossification 0.4273347663175035 0.4766404456896213 0.6336181773688634 1.0 1.0 10 P22413,Q96QD8,P17612 3 +Nanomaterial induced apoptosis 0.4668333229267284 0.4695689200209781 0.6386630341291744 1.0 1.0 6 O95831 1 +Mirna regulation of prostate cancer signaling pathways 0.4435180204410897 0.456784383474058 0.6478260315193536 1.0 1.0 7 P62993,Q8NCF5,P42345,Q02750,P04637,P35222 6 +Nrp1triggered signaling pathways in pancreatic cancer 0.4095132920256021 0.4560131926255905 0.6483804914696485 1.0 1.0 12 P00533,O14786 2 +Interleukin11 signaling pathway 0.3825767826059324 0.4433623009451106 0.6575036994438057 1.0 1.0 17 P17301,P23458,P07947,O00459 4 +Disruption of postsynaptic signaling by cnv 0.4251365471428978 0.4396747965529052 0.6601726591932835 1.0 1.0 9 Q14168,Q06787 2 +Monoamine transport 0.6279014353744911 0.4362600258534297 0.662648081161552 1.0 1.0 3 Q92692 1 +Il9 signaling pathway 0.4240681534597076 0.4350219321996301 0.6635465078988145 1.0 1.0 9 P23458,O00459 2 +Orexin receptor pathway 0.3668650280156326 0.4285570108401225 0.6682456361114035 1.0 1.0 22 P01130,P17252,Q9P0J1,O00459,P11166,Q13595 6 +Oxidative phosphorylation 0.3545556089893785 0.4192579873993007 0.675027597131892 1.0 1.0 30 Q15904,P51970,O75787,O96000,Q9Y6M9 5 +Reninangiotensinaldosterone system raas 0.6153514530479672 0.400921825698213 0.6884776802785475 1.0 1.0 3 Q14012 1 +Nanoparticlemediated activation of receptor signaling 0.42251472353375 0.3990756538796328 0.6898374607110842 1.0 1.0 8 P00533,P05556 2 +Nrf2are regulation 0.4142541441623753 0.392749421509777 0.6945045646098689 1.0 1.0 9 P07947,Q14145 2 +T cell receptor and costimulatory signaling 0.4569892473118247 0.3891877039332431 0.6971372987018198 1.0 1.0 5 P48729,P19174,Q15118,P17252 4 +Oncostatin m signaling pathway 0.3713634361094932 0.3891733519130307 0.6971479147689377 1.0 1.0 18 P23458,P01130,P62993,P17252 4 +Thymic stromal lymphopoietin tslp signaling pathway 0.3855531353561691 0.3600232355765771 0.7188297575796843 1.0 1.0 13 P23458,Q9BTU6 2 +Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition 0.4793613763881832 0.3554243002606751 0.7222717467637425 1.0 1.0 4 P08670 1 +Integrinmediated cell adhesion 0.3509043038046017 0.3517158270374406 0.7250513897932247 1.0 1.0 25 P17301,P06756,P62993,Q14185,P31751,O00459,P05556 7 +Mitochondrial complex i assembly model oxphos system 0.3465672514061297 0.3400487562692142 0.7338198111378258 1.0 1.0 28 O75380,Q9BUB7,Q9NPL8,P51970,O75306,O43676,O96000,Q9Y6M9 8 +Fragile x syndrome 0.3364759675059421 0.3211040276591834 0.7481315581741468 1.0 1.0 46 P62993,P10644,Q14118,Q06787,Q14012,P17612,P05067 7 +Cytosine methylation 0.4360098178631141 0.3206950085920562 0.7484415302342087 1.0 1.0 5 P48735 1 +Histone modifications 0.37899383755028 0.3090746790507717 0.7572647200108382 1.0 1.0 12 Q96KQ7 1 +Type i collagen synthesis in the context of osteogenesis imperfecta 0.3747581142590622 0.3071082417205148 0.7587609846642365 1.0 1.0 13 O75718,Q32P28 2 +Egfr tyrosine kinase inhibitor resistance 0.3508117563710508 0.3066844556614834 0.7590835625799899 1.0 1.0 21 P17252,P62993,P31751,P23458,P00533,O00459 6 +Tgfbeta receptor signaling 0.4309416200188051 0.3049029666354192 0.7604400562364417 1.0 1.0 5 P23458 1 +Tgfbeta receptor signaling in skeletal dysplasias 0.4309416200188051 0.3049029666354192 0.7604400562364417 1.0 1.0 5 P23458 1 +Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms 0.3874480942940839 0.3001063039515511 0.7640960708514852 1.0 1.0 10 O95819 1 +Cell migration and invasion through p75ntr 0.3971066040006024 0.2792790556361225 0.7800306782601734 1.0 1.0 7 Q9ULH0 1 +Endometrial cancer 0.3590402471601107 0.2733359244545052 0.7845950026394091 1.0 1.0 15 P62993,P31751,P00533,O00459,P35222 5 +Tgfbeta signaling pathway 0.3191104950029954 0.2027061010355388 0.8393647542420688 1.0 1.0 37 P17301,O14964,Q96J02,O00459,P05067,P05556 6 +Microglia pathogen phagocytosis pathway 0.4192421392099018 0.1986834037796896 0.8425104070705733 1.0 1.0 4 P16885,O00459,P63000 3 +Transcriptional activation by nrf2 in response to phytochemicals 0.3856179798869806 0.1944000972859038 0.8458626137497969 1.0 1.0 6 Q14145 1 +Pathogenic escherichia coli infection 0.3251393150235563 0.1788034246238963 0.8580920561596159 1.0 1.0 23 Q9BVA1,Q9BUF5,P17252,Q16625,P07437,P35222,P05556 7 +Ethanol effects on histone modifications 0.3480127572281332 0.1714514424137062 0.8638688083536994 1.0 1.0 12 Q96KQ7 1 +Alpha 6 beta 4 signaling pathway 0.3453918844237256 0.1604903625770839 0.8724948127758438 1.0 1.0 12 P07942,O00459,P62993,P17252 4 +Breast cancer pathway 0.3200183784735043 0.1590008213072866 0.8736682267541962 1.0 1.0 29 Q04721,O14641,P62993,P31751,P42345,P00533,O00459,P67870 8 +Glycogen synthesis and degradation 0.3248139876993017 0.1404935984072296 0.8882700100586367 1.0 1.0 20 Q04446,Q93100,Q16537 3 +Gpr40 pathway 0.4888718768112036 0.1354272697277757 0.8922740646136842 1.0 1.0 3 P29992 1 +Mitochondrial complex iii assembly 0.3500682065148323 0.1275769344288578 0.8984837856089267 1.0 1.0 7 Q6DKK2,P08574 2 +Il6 signaling pathway 0.3326749513750642 0.116383535894952 0.9073485831704136 1.0 1.0 13 P23458,O00459 2 +Gastrin signaling pathway 0.3120086237243412 0.1159119962022132 0.9077222881901496 1.0 1.0 31 P62993,P17252,P42345,P00533,O00459,P46108,P17612,P07947,P05556 9 +Type 2 papillary renal cell carcinoma 0.3382827167289203 0.1102292378864193 0.9122275750756248 1.0 1.0 10 O14641,P11166 2 +Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.342131891594695 0.1098595543181844 0.9125207593036196 1.0 1.0 8 Q13418,P42345,P05556 3 +Vasopressinregulated water reabsorption 0.3203285627943836 0.1091913277706932 0.9130507386182825 1.0 1.0 19 O43237,O60266,P17612,P22694 4 +Burn wound healing 0.3414043583535049 0.1076960194408169 0.9142368271752704 1.0 1.0 8 O60885,P50454,P09429,P04637,P31949,Q99439,P08670 7 +Adipogenesis 0.3250655864572814 0.1069979424901705 0.9147906120404286 1.0 1.0 15 P14174,O14654,O00767,O75844,P35222 5 +Caloric restriction and aging 0.3681805966138117 0.1047515688215176 0.9165729410131428 1.0 1.0 4 P43490,P42345,P04637 3 +Target of rapamycin tor signaling 0.3350078557440892 0.0947157500595014 0.9245406074827902 1.0 1.0 9 Q6PHR2,P17252 2 +Epithelial to mesenchymal transition in colorectal cancer 0.3112757282657051 0.093982704568688 0.9251228956733256 1.0 1.0 23 Q04721,P62993,P19022,Q16625,P31751,O00459 6 +Glial cell differentiation 0.431909750201446 0.076683619933721 0.9388752355661298 1.0 1.0 2 P09543 1 +Mitochondrial complex ii assembly 0.4316411496105289 0.0765373958234783 0.9389915636499744 1.0 1.0 2 P21912 1 +Unfolded protein response 0.345874764848155 0.0754947724173775 0.9398210566755624 1.0 1.0 4 P05198,Q14790,P04637 3 +Kisspeptinkisspeptin receptor system in the ovary 0.3303760377275098 0.0748981811379442 0.9402957237357804 1.0 1.0 7 P31751 1 +H19 action rbe2f1 signaling and cdkbetacatenin activity 0.334783940397877 0.0741181265704817 0.9409163920137 1.0 1.0 5 Q16527 1 +Wntbetacatenin signaling pathway in leukemia 0.3418435904326733 0.0709370375893609 0.9434478658773366 1.0 1.0 4 P48729,P35222,P14923 3 +Proteasome degradation 0.3044670914695587 0.0642560962931812 0.9487663112547406 1.0 1.0 41 P10321,P04439 2 +Pancreatic adenocarcinoma pathway 0.3055397881339599 0.0560817745814642 0.9552766628626396 1.0 1.0 25 P23458,P00533,P31751,P11233 4 +Brainderived neurotrophic factor bdnf signaling pathway 0.3060661355192535 0.05591471171573 0.9554097509110996 1.0 1.0 48 Q99523,P13591,P62993,Q13501,P19022,P42345,Q12959,P10586,P67809,O00459,Q14012,Q9ULH0 12 +Eicosanoid synthesis 0.2919688423314595 0.0495627826772414 0.9604708052832688 1.0 1.0 2 Q9H7Z7 1 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.3039344638674615 0.0473889171900288 0.9622032618988874 1.0 1.0 28 Q15392,O75845,P56937,Q15800,Q16850,Q9UBM7 6 +Nonsmall cell lung cancer 0.3062123515338065 0.0458013679288354 0.9634685685071596 1.0 1.0 21 P00533,O00459,P31751,P62993 4 +Somatroph axis gh and its relationship to dietary restriction and aging 0.3680816765179913 0.0417469466486859 0.9667004285466264 1.0 1.0 3 P42345,P08069 2 +Regulation of apoptosis by parathyroid hormonerelated protein 0.3067224740278236 0.0340905554158101 0.9728049397954424 1.0 1.0 5 Q9HB09,Q07820 2 +Cellular proteostasis 0.3108389647185047 0.0251478571223672 0.9799370277735592 1.0 1.0 6 O15212 1 +Il2 signaling pathway 0.3107450489149479 0.0236986743016743 0.9810929634639792 1.0 1.0 11 P23458 1 +Imatinib and chronic myeloid leukemia 0.2612352238624221 0.0184713714927964 0.9852628159076257 1.0 1.0 4 P08183 1 +Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.3089694208811923 0.0175795598358777 0.9859742630460816 1.0 1.0 10 P31943 1 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..4ad6fadc9e9a662a1867ba7cef99cdceb845d468 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Activation of nlrp3 inflammasome by sarscov2", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoe and mir146 in inflammation and atherosclerosis", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Covid19 adverse outcome pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgf23 signaling in hypophosphatemic rickets and related disorders", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Ganglio sphingolipid metabolism", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes associated with the development of rheumatoid arthritis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpcrs class b secretinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Id signaling pathway", "Il1 and megakaryocytes in obesity", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Ldlrad4 and what we know about it", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Major receptors targeted by epinephrine and norepinephrine", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir5093p alteration of yap1ecm axis", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirna targets in ecm and membrane receptors", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanomaterialinduced inflammasome activation", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nonclassical role of vitamin d", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoblast signaling", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 altering angiogenesis via nrp1", "Sarscov2 and ace2 receptor molecular mechanisms", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selective expression of chemokine receptors during tcell polarization", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABHD16A", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACE2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADCY3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG9", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APBB1", "APC", "APEX1", "APIP", "APLP2", "APMAP", "APP", "APRT", "ARAF", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP2", "ARG2", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID4B", "ARL2", "ARL3", "ARL6", "ARL8B", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARVCF", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATG7", "ATG9A", "ATIC", "ATM", "ATP11C", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "BAG2", "BAG4", "BAIAP2", "BAK1", "BANF1", "BAP1", "BARD1", "BAZ1A", "BAZ1B", "BCAS3", "BCAT1", "BCAT2", "BCKDK", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BLM", "BLVRA", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD4", "BRIP1", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "C1QBP", "C21orf59", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CAP1", "CAPN1", "CAPN2", "CAPZB", "CARM1", "CASK", "CASP8", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR2", "CCDC124", "CCDC6", "CCNB1", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC6", "CDC73", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK7", "CDK9", "CDKAL1", "CDKN2A", "CDS2", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CEP170", "CEP250", "CEP290", "CEP44", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHKA", "CHMP5", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIP2A", "CIT", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLIC1", "CLK2", "CLK3", "CLPTM1L", "CLTA", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT10", "CNOT9", "CNP", "COA3", "COASY", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ8A", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CRAT", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSL", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAG1", "DAGLB", "DARS", "DAXX", "DBI", "DBNL", "DCAF1", "DCAF7", "DCP1A", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDAH2", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMD", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC3", "DSG2", "DSP", "DSTN", "DTX3L", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EGFR", "EGLN1", "EHD1", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOB", "ELP3", "ELP4", "EMD", "EML4", "ENAH", "ENO1", "ENO2", "ENPP1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA2", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERI1", "ESD", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOSC2", "EXOSC7", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF1", "FAH", "FAM120A", "FAM91A1", "FANCA", "FANCD2", "FANCI", "FARSB", "FASN", "FAT1", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIS1", "FKBP10", "FKBP15", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FOXC1", "FOXRED1", "FREM2", "FSCN1", "FTL", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNS", "GALNT1", "GAPDH", "GART", "GBA", "GBE1", "GCC2", "GCDH", "GCLC", "GCLM", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GID4", "GID8", "GIGYF2", "GIT1", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GM2A", "GMPPB", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPS1", "GPT2", "GRB2", "GRSF1", "GSK3A", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF2I", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP3", "ILF2", "ILK", "IMP3", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRS4", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JAK1", "JUP", "KAT5", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDM5B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIDINS220", "KIF15", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFAP3", "KIRREL1", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LAMC1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMNA", "LMNB1", "LMNB2", "LONP2", "LPGAT1", "LRIG1", "LRP1", "LRP2", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM4", "LSM7", "LSS", "LTA4H", "LZTFL1", "MACF1", "MAD2L1BP", "MAGED1", "MAGT1", "MANF", "MAP1B", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC2", "MARCKS", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME2", "MECP2", "MED1", "MED14", "MEPCE", "MFAP1", "MFGE8", "MFN2", "MGA", "MGAT2", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MMADHC", "MOCS1", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPI", "MPP1", "MPP2", "MPST", "MRE11", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTR", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO5A", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAM1", "NCAPG", "NCAPG2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCOA4", "NCOR1", "NCSTN", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEO1", "NEU1", "NF1", "NF2", "NFATC2IP", "NFRKB", "NIPBL", "NKRF", "NLRX1", "NME1", "NME2", "NME3", "NME4", "NONO", "NOP2", "NOTCH2", "NPC1", "NPC2", "NR2F1", "NRP1", "NSD1", "NSDHL", "NSF", "NT5C3A", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "ORC1", "ORC2", "ORC3", "OSBPL3", "OSTM1", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAK2", "PAN2", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDLIM7", "PDP1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PEBP1", "PECR", "PELO", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PGS1", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PIAS1", "PIBF1", "PIGT", "PIK3C2A", "PIK3R2", "PIK3R4", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLCG1", "PLCG2", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMPCA", "PMVK", "PNKP", "PNP", "PNPT1", "PODXL", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKACB", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPRF", "PTRH2", "PURA", "PUS1", "PXMP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB13", "RAB14", "RAB21", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RB1CC1", "RBBP7", "RBM14", "RBM17", "RBM39", "RBM4", "RBM5", "RBMX", "RBPJ", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RELA", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOG", "RIF1", "RIPK1", "RMI1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF20", "RNF40", "RNMT", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRM2B", "RTCB", "RTF1", "RTN3", "RTN4", "RUVBL1", "S100A10", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SARS", "SC5D", "SCAF11", "SCAMP2", "SCAP", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEL1L", "SELENBP1", "SELENOI", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SFPQ", "SFSWAP", "SGPL1", "SGSH", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIN3A", "SIRT1", "SIRT2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORT1", "SPEN", "SPHK2", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRPK2", "SRRM1", "SRSF1", "SRSF10", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSR3", "SSR4", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STIM1", "STIP1", "STK3", "STK4", "STMN1", "STOM", "STRAP", "STUB1", "STXBP2", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SUZ12", "SYNE1", "SYNE2", "TAB1", "TALDO1", "TAP1", "TARDBP", "TBC1D4", "TBCA", "TBL2", "TCF20", "TCP1", "TCTN3", "TECR", "TEDC1", "TELO2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMELESS", "TIMMDC1", "TIPRL", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TMED10", "TMEM126B", "TMEM38B", "TMEM43", "TMEM70", "TMEM98", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOLLIP", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP3A", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM32", "TRIM33", "TRIO", "TRIP13", "TRIP4", "TRPC4AP", "TRRAP", "TSG101", "TSPO", "TSPYL1", "TTC19", "TTC21B", "TTC26", "TTF2", "TTK", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2L3", "UBE2N", "UBE3A", "UBIAD1", "UBR5", "UBTF", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNG", "UPF1", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP10", "USP32", "USP5", "USP7", "USP9X", "UTRN", "VANGL1", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VLDLR", "VMP1", "VPS11", "VPS18", "VPS28", "VPS33A", "VPS37B", "VPS4A", "WAPL", "WARS", "WASF2", "WASL", "WDHD1", "WDR1", "WDR26", "WDR48", "WDR5", "WDR74", "WFS1", "WIPI2", "WNK1", "WRN", "XAB2", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YES1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZNF281", "ZNF318", "ZYX"], "leading_proteins": ["ABCB1", "ADCY3", "ADGRE5", "AGPS", "AIFM1", "AKAP8", "AKT2", "APBB1", "APLP2", "APP", "ASAH1", "ATG9A", "ATP1B1", "ATP6AP1", "ATP6AP2", "ATP6V1E1", "BARD1", "BCL2L12", "BRAP", "BRD4", "C1QBP", "CADM1", "CALM3", "CAMK1", "CANT1", "CASK", "CASP8", "CD47", "CDH2", "CERS1", "CERS2", "CHKA", "CHPF2", "CHST14", "CLPTM1L", "CNN2", "CNP", "COA3", "COLEC12", "COMT", "CPT2", "CRK", "CRTAP", "CSNK1A1", "CSNK2B", "CSRP2", "CTBP1", "CTBP2", "CTNNB1", "CTNND1", "CTSB", "CTSL", "CXADR", "CYB5B", "CYC1", "CYP51A1", "DAG1", "DAGLB", "DDX3X", "DHCR24", "DHCR7", "DLG1", "DNM1L", "DOCK1", "DSC3", "DVL2", "DYNC1LI2", "ECE1", "EGFR", "EHD1", "EHMT1", "EHMT2", "EIF2S1", "EIF4B", "EMD", "ENPP1", "EPHA2", "EPHX2", "F11R", "FAT1", "FIS1", "FLOT1", "FLOT2", "FMR1", "FREM2", "FTL", "FUCA1", "FUS", "GALNS", "GBA", "GBE1", "GLA", "GLB1", "GM2A", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNPAT", "GNS", "GPAM", "GRB2", "GUSB", "HEXA", "HEXB", "HGS", "HLA-A", "HLA-B", "HLA-C", "HMGB1", "HNRNPH1", "HS2ST1", "HSD17B7", "IDH2", "IFNGR1", "IGF1R", "ILK", "IMPAD1", "INPP4A", "IRS4", "ITCH", "ITGA2", "ITGAV", "ITGB1", "JAK1", "JUP", "KDSR", "KEAP1", "KIDINS220", "KIF23", "KIF5B", "KLC4", "LAMB1", "LDLR", "LGALS3BP", "LRIG1", "LRP1", "LRP2", "LRRC8A", "MAP2K1", "MAP4K4", "MCL1", "MFGE8", "MFN2", "MIF", "MPP1", "MPP2", "MSMO1", "MTMR2", "MTMR4", "MTOR", "NAA40", "NAGLU", "NAMPT", "NAP1L1", "NCAM1", "NCOA4", "NCSTN", "NDUFA8", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS2", "NDUFS6", "NECTIN2", "NEDD4", "NEO1", "NEU1", "NFATC2IP", "NOTCH2", "NPC1", "NPC2", "NRP1", "OCLN", "OSTM1", "P3H1", "PANX1", "PDK1", "PDP1", "PFDN6", "PHKB", "PI4K2A", "PIK3R2", "PKMYT1", "PLCG1", "PLCG2", "PODXL", "PPP2R5E", "PRKACA", "PRKACB", "PRKAR1A", "PRKCA", "PSMA6", "PSMB2", "PSMB7", "PTGES2", "PTPRF", "RAB3B", "RAB7A", "RAC1", "RACGAP1", "RALA", "RB1CC1", "ROBO1", "S100A11", "SC5D", "SCARB1", "SCARB2", "SCD", "SDCBP", "SDHB", "SERPINH1", "SGPL1", "SLC19A1", "SLC2A1", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC6A15", "SLIT2", "SNAP23", "SORT1", "SPHK2", "SPTLC1", "SQSTM1", "STAM", "STK3", "STOM", "STXBP2", "TFRC", "TIMMDC1", "TMEM70", "TMEM98", "TP53", "TPM3", "TRA2A", "TTC19", "TUBB", "TUBB2B", "TUBB6", "UBE3A", "UGCG", "ULK3", "VANGL1", "VDAC1", "VDAC2", "VDAC3", "VIM", "VLDLR", "YBX1", "YES1", "ZMPSTE24"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json b/opencell_localization/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/opencell_localization/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/opencell_localization/basic/idx2term.json b/opencell_localization/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..7e470da8da5070b3db1d8e3d3918e26c1dcbbc79 --- /dev/null +++ b/opencell_localization/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "mitochondria", "1": "golgi", "2": "vesicles", "3": "membrane"} \ No newline at end of file diff --git a/opencell_localization/basic/plot_0.png b/opencell_localization/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b144f371d4ccf08f661bf1270ac61e712f8b91a1 --- /dev/null +++ b/opencell_localization/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0c382c6e9a9120197861974a9b6b583753dfe7d05e6d51f068c547dda8c9637a +size 129900 diff --git 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0000000000000000000000000000000000000000..8c0448452d453190253982c62a9fba424955ce3a --- /dev/null +++ b/opencell_localization/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d6f24fe2a1eab0cc0e6747d9598515e173b9c029df7848e9752e2f5149fdd8ae +size 140737 diff --git a/opencell_localization/consensus.joblib b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..310dd940c838d12cc890f273b5779e9d314b6ec6 --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:207ec5861bb926cf9583332a4a0da70994a88de2820af3b748ddca1de7f5bb0e +size 82734 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ce97dbaea1cea3cc4cbb828ae0836f3b307293bb --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 105.94117647058823 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..328ec015fac1efd515bd5b0c1a5a2526ed80384e --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..60f04fd3b196eed8aa332bd53c771c2527bbf4af --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +mitochondria 0.688360570428257 1.8152561755479264 0.0694845504098045 0.7060313622135582 0.5906186784833383 11 P21796,Q9NVH1,Q15388,P45880,Q9NR31,Q9Y277,Q8IWA4 7 +golgi 0.3848522904141631 1.0642563899691535 0.2872125679655684 0.9968353872720772 0.6103267069268328 70 Q7Z3C6,P53365,O15127,Q15904,Q13190,O75787,Q8IZA0,Q8NBN3,Q9Y487,P54920,Q5VW38,Q8IXU6,Q9H0U4 13 +vesicles 0.480624541465027 0.5460615428941225 0.5850236337758565 0.9999996790797082 0.6761751142302834 197 Q93050,Q7Z3C6,Q13501,Q9BTU6,Q15904,P51149,Q8IY95,Q13614,O15173,P13473,Q9H6H4,Q8WUH2,Q13308,O15400,Q9Y3E7,Q96PE3,Q5VW38,Q9UEU0,P47756,Q9Y2Q5,Q99747,O95470,O15127,Q969T9,O75845,Q8IZD4,O95249,Q8IZA0,O15269,Q14145,Q06481,P17612,Q06136,P11166,P54920,P51798,Q9UK41,Q9H9H4,P04439,Q9NUM4,Q15392,Q86Y82,O75787,O00429,P42345,Q15758,P02786,Q8NBN3,O00459,P11279,P35222,O96005,Q96L92,O15027,O14653,Q9H0U4,O43752,P17252,Q5HYI8,Q9H2J7,P31751,P51151,Q9UNK0,Q92783,P30825,P41440,Q9NP72,Q6PHR2,Q8IXU6,O14964 70 +membrane 0.3548015377027157 0.5292599982769755 0.5966251007914265 0.9999998018241232 0.6761751142302834 93 P04439,Q9NUM4,O15127,Q9Y6W5,Q9UKS6,Q9UQB8,P31751,Q13740,P02786,Q9Y4F1,O00459,Q13308,O95819,P30825,P41440,P67870,P07947,P08670 18 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..be15332f479af2c5724a3f01d038abe493859459 --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ACAP2", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AGAP3", "AHCY", "AHSA1", "AKAP12", "AKAP13", "AKAP8L", "AKR1A1", "AKT2", "ALCAM", "ALDH9A1", "ANAPC16", "ANAPC2", "ANAPC4", "ANKRD17", "ANKRD52", "ANXA11", "AP2B1", "AP2S1", "APC", "APLP2", "ARAF", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL6IP6", "ARL8B", "ARPC2", "ARPC3", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATL2", "ATL3", "ATM", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATXN10", "ATXN2L", "AURKB", "BAG4", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BET1", "BLM", "BLVRA", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRD3", "BRD4", "BTF3", "BUB1B", "BUD23", "BYSL", "C12orf57", "C1orf123", "C21orf59", "C8orf33", "CAD", "CALD1", "CALM3", "CAMK1", "CAMK2G", "CANX", "CAPRIN1", "CAPZB", "CBX1", "CCAR1", "CCDC22", "CCDC47", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2BP2", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK7", "CDK9", "CDKN2A", "CDS2", "CEP170", "CEP250", "CETN2", "CHEK1", "CHEK2", "CHM", "CHMP2B", "CHMP3", "CHMP7", "CHUK", "CKAP2", "CKAP4", "CKAP5", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLINT1", "CLK2", "CLK3", "CLNS1A", "CLPTM1", "CLTA", "CLTB", "CLTC", "CNN2", "COIL", "COL4A3BP", "COPA", "COPB2", "COPE", "COPG1", "COPG2", "COPZ1", "CORO1B", "CORO1C", "CPSF6", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNB1", "CTNNBL1", "CTPS1", "CTTN", "CYB5R3", "CYP51A1", "DAD1", "DBNL", "DCP1A", "DCP1B", "DCP2", "DCTN2", "DDB1", "DDOST", "DDX21", "DDX39B", "DDX47", "DDX5", "DDX56", "DDX6", "DHCR24", "DHX37", "DHX9", "DIAPH1", "DKC1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB4", "DNAJB6", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DOCK7", "DPH2", "DRG1", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EBNA1BP2", "EBP", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1G", "EFTUD2", "EIF2AK2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3K", "EIF3M", "EIF4A1", "EIF4A3", "EIF5", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMG1", "ENO1", "ENY2", "EPN1", "EPS15", "ESD", "ESYT1", "EWSR1", "EZR", "FAM120A", "FAM50A", "FANCA", "FARP1", "FASN", "FAU", "FBL", "FDPS", "FKBP5", "FKBP8", "FNBP1", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAK", "GAPDH", "GAR1", "GBF1", "GDI1", "GDI2", "GET4", "GGPS1", "GNL2", "GNL3", "GOLGA2", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GPAT4", "GPR107", "GRB2", "GSK3A", "GSPT1", "GTF2F1", "GTPBP4", "GYG1", "GYS1", "H1F0", "HDAC1", "HDAC2", "HEATR3", "HGS", "HIP1", "HLA-A", "HMGA1", "HMGB2", "HMGCS1", "HMGN2", "HNRNPA0", "HNRNPC", "HNRNPD", "HNRNPH1", "HNRNPL", "HNRNPU", "HSP90AA1", "HSP90AB1", "HSPA12A", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPBP1", "HSPH1", "IDI1", "IGF1R", "IGF2BP1", "IGF2BP3", "ILF3", "ILK", "IMP3", "INPP4A", "INTS14", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IST1", "ITSN2", "KDSR", "KEAP1", "KIAA0319L", "KIAA0368", "KIF11", "KIF20A", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFAP3", "KIFBP", "KIFC1", "KLC1", "KLC2", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "LAMP1", "LAMP2", "LAMTOR2", "LARP7", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LIG1", "LMNA", "LMNB1", "LPCAT1", "LRIG1", "LSM14B", "LSS", "LTV1", "MAP2K1", "MAP3K7", "MAP4", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARK2", "MBOAT7", "MCM10", "MDH1", "MECP2", "MED14", "MED17", "MED21", "MED24", "MED25", "MED27", "METAP2", "MFN1", "MFN2", "MIF", "MKI67", "MMGT1", "MPHOSPH10", "MRTO4", "MSH6", "MSN", "MTMR2", "MTOR", "MVD", "MVK", "MYBBP1A", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO6", "NAF1", "NANS", "NAPA", "NAPG", "NCAPH", "NCKAP1", "NCL", "NCLN", "NECAP2", "NEK9", "NEMF", "NEPRO", "NHP2", "NIFK", "NMD3", "NOL10", "NOL11", "NOM1", "NONO", "NOP10", "NOP2", "NOP53", "NOP58", "NPM1", "NRBP1", "NSA2", "NSDHL", "NUCKS1", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP214", "NUP35", "NUP98", "NUTF2", "NVL", "NXF1", "OCRL", "OSBP", "OSBPL11", "OSBPL8", "PABPC4", "PACSIN2", "PACSIN3", "PAK2", "PARP1", "PBK", "PCNA", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PES1", "PEX3", "PFDN6", "PFN1", "PGK1", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIK3C2A", "PIK3R2", "PIN4", "PIP4K2C", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PMPCA", "PMVK", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "POLR3E", "PPM1G", "PRKAA1", "PRKACA", "PRKCA", "PRKCD", "PRKDC", "PRPF19", "PRPF4B", "PRPF8", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTDSS1", "PTDSS2", "PTGES3", "PTK7", "PXN", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB7A", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RABL3", "RAC1", "RACK1", "RAD21", "RAN", "RANBP1", "RANBP2", "RANBP9", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "REEP3", "REEP4", "REEP5", 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0.0091303730417641 6.309554266185252e-05 0.0001822132476349 0.0049581021616823 0.0594068486772054 +membrane trafficking regulatory protein 6 22 2.7596213505708755 0.0057868390640114 4.949029126213592 18.78640776699029 1.0645815505395402 0.2320552342124929 2.3097144002673033 2.893415643517755 1.4460865220385617 0.2677048300346334 0.0005239549442866 0.2298835505782255 0.0142561824639166 0.0016490180911792 0.0134115286949534 +serine protease 6 20 2.6444011774699514 0.008183559907551 5.662621359223301 17.516990291262136 1.1445634795625386 0.1820139001244477 2.0809494011218104 1.6626107291843584 1.568325484830445 0.2384821649427795 0.0019601597157597 0.0239365913087713 0.0012207780133745 0.0010882828125207 0.0022373634783845 +SNARE protein 11 15 2.64137480869389 0.0082570316749488 4.660194174757281 11.12378640776699 0.9288896561072936 0.3201954718639376 2.5506648592929815 2.745113440103806 1.1546709449924732 0.3042666981599379 0.0009765066889198 1.0 1.0 0.0048864602536943 4.8333003973829006e-08 +transmembrane signal receptor 8 15 2.549331426014052 0.0107929675893825 3.266990291262136 7.169902912621359 1.6693846681257831 0.1085289610325799 1.5770125590990791 1.7927217985188668 1.0928815816574815 0.16461969248918 0.0383824497634568 0.3651094145888684 0.2213471409258044 0.0713615966922901 0.0337599745575505 +apolipoprotein 4 6 2.505091906038051 0.0122419578544605 0.6503856041131105 2.437017994858612 0.932382076838194 0.2433812620783314 0.949160692915208 1.2312417090911711 1.6649876261886865 0.2763167407189011 3.368893008845366e-05 0.0711332726649859 0.0003602808960722 1.934192081629664e-05 0.0005240184523993 +glycosidase 3 5 2.3999593715597616 0.0163968916475845 2.349514563106796 4.621359223300971 -0.2307336370526829 0.2597902373581335 1.0699672244692364 0.6012366681705257 1.6034021241460206 0.2766391836749902 1.724507092554698e-05 3.8308667598491466e-06 2.747580602519606e-07 1.093284607508717e-05 0.0001695148193701 +G-protein coupled receptor 3 5 2.156341173848255 0.031057034446595 1.4044665012406947 3.064516129032258 0.9626184815288628 0.1913432504342112 0.870058838741881 1.0917268182881792 1.5495402432590264 0.2299939379384595 0.0064450358458905 1.0 0.2372212797486779 0.0042924995678 0.0443313868612348 +protease inhibitor 2 11 2.0817074934190005 0.03736919576077 2.9101941747572817 8.470873786407767 -0.2314103697452487 0.4582528635483486 1.848429656574973 1.4867133927645466 1.0472458882274065 0.2976253017490123 0.058960012286042 0.1499686155438198 0.0398064357050217 0.0444854600227105 0.2134840601212924 +membrane traffic protein 15 77 2.059293526811748 0.0394661282184789 17.393203883495147 64.0364077669903 0.6866153002436179 0.5279969401351168 6.983388919650095 8.417857504136053 1.0746394007588131 0.378481933491251 0.0214710596146359 1.0 0.0574136821119774 0.0108638198964117 0.0026249851989894 +phospholipase 1 9 1.989396950218289 0.0466574060131264 2.0266990291262137 7.405339805825243 0.812358854363279 0.2972812642592555 1.2910317153343125 1.5290934655146406 1.1524828353366978 0.2736190413418742 0.1944778963944218 0.0093923264669034 0.0334071197556988 0.1627514901813832 0.4305195758208063 +cadherin 3 5 1.9858496000853636 0.0470500264025308 1.555825242718447 3.0558252427184467 -0.2693089236279177 0.4378099575304214 1.0377767725547085 1.0517161419538543 1.2797396443463749 0.3315735399503712 0.0118457633601407 1.0 0.1596960736798767 0.0086586519898169 0.0096830476876922 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..446eb6287286953682055caf408bf5e68f48f8b8 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 165, + "title": "Average number of proteins per term", + "value": 15.16969696969697 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6a7441132dff625e132200784da69d0daf62dd88 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6c3dfe459b42a3923056ea2cad0563397c595034 --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,54 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +cysteine protease 0.6791010111634194 2.9175808917555197 0.0035275813679258 0.4418234464463286 0.2213648522225221 34 Q99538,P07711,P53634,P07858,Q13510,Q92820 6 +membrane trafficking regulatory protein 0.7351642216574661 2.7596213505708755 0.0057868390640114 0.6161877850541748 0.2213648522225221 22 P13473,P24390,O00560,P11279,Q8WTV0,Q14108 6 +serine protease 0.7360341450958907 2.6444011774699514 0.008183559907551 0.7422700101474491 0.2213648522225221 20 O14773,P42785,Q9HB40,Q9H3G5,Q2T9J0,P10619 6 +SNARE protein 0.7931259792796509 2.64137480869389 0.0082570316749488 0.7454011510739116 0.2213648522225221 15 O43752,Q9P2W9,Q86Y82,O00161,O95249,Q9UNK0,O15400,O95721,P51809,Q5SQN1,Q9UEU0 11 +transmembrane signal receptor 0.7744232527586572 2.5493314260140516 0.0107929675893825 0.8331265666599106 0.2213648522225221 15 Q8WUJ1,P29317,P15260,P14543,O75787,Q15375,P00533,O94898 8 +apolipoprotein 0.9567317494856096 2.505091906038051 0.0122419578544605 0.8689778378834839 0.2213648522225221 6 P01130,Q9NPF0,Q07954,P98155 4 +glycosidase 0.9565330415899836 2.3999593715597616 0.0163968916475845 0.934644481478027 0.225457260154287 5 P06865,P07686,Q9BTY2 3 +major histocompatibility complex protein 0.9645256651437764 2.2289102735870254 0.0258198754201619 0.9866500793058962 0.3014359225698929 4 P10321,P55899,P04439 3 +G-protein coupled receptor 0.8940128282927022 2.156341173848255 0.031057034446595 0.9945146375310892 0.3014359225698929 5 Q8NBN3,Q5VW38,P48960 3 +protease inhibitor 0.7444964171444335 2.0817074934190005 0.03736919576077 0.9981342236797948 0.3245219631856344 11 P05067,Q06481 2 +membrane traffic protein 0.4718132743132509 2.0592935268117474 0.0394661282184789 0.9986980542312656 0.3255955578024513 77 Q9H4M9,Q99523,Q99747,Q96PC5,P20645,A6NIH7,P43307,Q9BRG1,Q9H6H4,Q92673,Q9Y3E7,Q9BQT9,P11717,Q9H223,O43493 15 +phospholipase 0.7573157497132674 1.989396950218289 0.0466574060131264 0.999623222878639 0.335117334636191 9 Q8NHP8 1 +cadherin 0.8512243100370585 1.9858496000853632 0.0470500264025308 0.9996479803643242 0.335117334636191 5 Q14574,Q14517,O60245 3 +primary active transporter 0.5714906918418313 1.933791239377832 0.0531388003583375 0.9998777516870092 0.335117334636191 27 Q9NS69,Q8N4H5,Q9H2J7,Q04656,O60888,P05026,Q96NB2 7 +oxygenase 0.7513345243203235 1.889535773214987 0.0588200740264739 0.999954711473178 0.335117334636191 8 P30519,Q6UW02,Q9BV57,Q16850,P19021 5 +protein modifying enzyme 0.5642717719444618 1.8854521731901597 0.0593688157686611 0.999958866423244 0.335117334636191 27 P33908,Q9UMR5,O75718,P50897,O15460,O00462,Q92791,O60725 8 +oxidoreductase 0.5142370929750179 1.863297666842467 0.0624203982319531 0.9999759372768278 0.335117334636191 46 O43396,Q8N0U8,O95831,Q08431,O43169,P51970,O75306,O43676,Q9BUP3,Q9P2K2,O96000,Q8N4Q0,Q9Y6M9 13 +oxidase 0.6550665650967213 1.859463709403675 0.0629614386286177 0.999978123316737 0.335117334636191 14 Q15800,Q6ZRP7,Q8NB78 3 +amino acid transporter 0.7858132606590453 1.7196731124984994 0.0854918779239504 0.999999605589428 0.3885961009866842 5 P30825 1 +phosphodiesterase 0.7157289153808677 1.66374757086893 0.096162885368459 0.9999999431306572 0.4068429765588653 7 Q92485 1 +extracellular matrix structural protein 0.955949503088912 1.6368994510698034 0.1016514806675799 0.9999999791838076 0.4096891450565237 2 Q5KU26 1 +kinase modulator 0.7334738578258523 1.597010507201433 0.110263365103711 0.9999999957524056 0.4231036102816818 6 P10644,P67870 2 +calmodulin-related 0.6030962827899029 1.5833235240634782 0.1133477438414067 0.9999999976050392 0.4250540394052754 14 Q14257,Q15293,P80303,P31949,P0DP25,O43852,Q02818 7 +cell adhesion molecule 0.9454594304137556 1.5651757388005452 0.1175417085200134 0.99999999890468 0.425420417144844 3 O00592,Q14118 2 +kinase activator 0.7474138789348779 1.5606682100582026 0.1186020556888656 0.9999999991017744 0.425420417144844 5 P14635,Q93100 2 +hydrolase 0.4994229681355605 1.5434338074646552 0.122725556249001 0.9999999995856628 0.4287754585161481 31 P34059,P51688,P15289,P15586,Q99519,Q68D91 6 +ion channel 0.7042503204032389 1.4721407758487997 0.1409828663346977 0.9999999999871084 0.4373198904610391 6 Q9C0H2,P51790 2 +metalloprotease 0.5030112508786959 1.4642601782423934 0.1431228732417946 0.999999999991458 0.4373198904610391 27 O75844,Q9UIQ6,P42892,P02786 4 +integrin 0.9065018807092956 1.4176455478012568 0.1562942751043121 0.999999999999337 0.4423520654828726 3 P17301,P06756 2 +protein-binding activity modulator 0.6864002513234346 1.3953868596457637 0.1628992116944077 0.9999999999998188 0.4423520654828726 6 Q9UNN8,Q9UBC1 2 +galactosidase 0.896023643202577 1.377956741391263 0.1682166445030741 0.9999999999999366 0.4423520654828726 3 P16278,P06280 2 +immunoglobulin receptor superfamily 0.8812785388127948 1.3315797492046813 0.1829983230624321 0.9999999999999968 0.4506675120194224 2 Q7KYR7 1 +tubulin 0.7337477658983322 1.3110557913124314 0.1898389151782589 0.9999999999999992 0.4539626232523582 4 P07437,Q9BVA1 2 +voltage-gated ion channel 0.8672049954493299 1.2689541042105188 0.2044574337328311 1.0 0.4621298159714675 3 P21796 1 +immunoglobulin superfamily cell adhesion molecule 0.8589846897663169 1.240948257554962 0.2146248639779608 1.0 0.4785554399508587 2 P43121 1 +viral or transposable element protein 0.8382590005373434 1.1599701281342425 0.2460609684277706 1.0 0.5185205588323979 3 Q9NUD5,Q9H2J4 2 +translation factor 0.5840127386747956 1.1270191402159713 0.2597343885873648 1.0 0.5185205588323979 8 P51116,P51114 2 +acyltransferase 0.4802901497803734 1.1197603931403457 0.2628158814445271 1.0 0.5185205588323979 20 Q8NCC3,Q9HCL2 2 +extracellular matrix protein 0.6086144531688662 1.0587144379327735 0.2897298504976242 1.0 0.5185205588323979 6 O75882 1 +phosphatase 0.47701217574673 1.0395647952631868 0.2985421399338048 1.0 0.5185205588323979 18 Q9H773,P11117,Q9NX62 3 +secondary carrier transporter 0.4602502217452031 1.022477718527946 0.3065548531229012 1.0 0.520757647558039 21 Q9BXP2,Q92581,Q15043,Q9Y6M7 4 +glycosyltransferase 0.4188364332003929 0.9805688086170286 0.3268054221824541 1.0 0.5227890915499693 33 Q86SF2,Q9P2E5,Q10472,O60512,Q8N6G5,Q16739,Q68CQ7,O94766,Q9Y673,Q10469,Q9Y2G5 11 +nucleotide phosphatase 0.5618414763469066 0.9722865471349134 0.3309080145804639 1.0 0.5227890915499693 7 Q8WVQ1 1 +heterotrimeric G-protein 0.5488848478185224 0.9633521429861382 0.3353708341352515 1.0 0.5227890915499693 8 P08754,P09471,Q14344,P04899,P63096,P29992 6 +ATP-binding cassette (ABC) transporter 0.5165405884616554 0.9561018013284628 0.3390208048233134 1.0 0.5227890915499693 11 P08183,Q03519,P33527,O14678 4 +kinase 0.3954835120042724 0.6645382390909966 0.5063458831868135 1.0 0.6848120551297068 25 Q9BTU6,Q8TCG2,Q9NRA0,P35790 4 +decarboxylase 0.5207888360414639 0.622163418593736 0.5338344174557188 1.0 0.7046614310415488 5 Q8NBZ7 1 +small GTPase 0.4194042160156519 0.4403719767133395 0.6596677178867614 1.0 0.8062605440838194 10 Q8IXI2,P11233,Q9HCN4,P61225 4 +protein phosphatase 0.3790909718689165 0.4131092903643291 0.679526543052352 1.0 0.8179406591279906 16 P10586,Q16537 2 +ATP synthase 0.3636037393984611 0.3871614632499101 0.6986366775849815 1.0 0.8193707903985071 21 Q93050,Q15904 2 +lyase 0.3480674460331551 0.1979260647474714 0.8431029108528993 1.0 0.9152103966495287 14 P22830,Q9UHG3 2 +primase 0.4300295460649854 0.0756723925807944 0.9396797405276878 1.0 0.9986935713165972 2 P49643 1 +transferase 0.2927294050362423 0.0117930917425455 0.9905906922780652 1.0 1.0 35 Q7LGA3,O43505 2 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e7fd4e2813a90363c5a5360ee88d4986c679fd96 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "C4 zinc finger nuclear receptor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "Rel homology transcription factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "amylase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "hydroxylase", "immunoglobulin receptor superfamily", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase inhibitor", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "storage protein", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AAK1", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD16A", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACE2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADAT3", "ADD1", "ADD2", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGK", "AGPAT1", "AGPAT5", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALG9", "ALKBH5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC7", "ANGEL1", "ANKFY1", "ANKHD1", "ANKRD17", "ANKRD52", "ANKS1A", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APIP", "APLP2", "APOL2", "APP", "APRT", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGDIA", "ARHGEF1", "ARID3B", "ARID4B", "ARIH1", "ARL1", "ARL6", "ARL6IP5", "ARPC1A", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARVCF", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATL2", "ATL3", "ATM", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATRN", "ATRX", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BAP1", "BAP18", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCKDHB", "BCKDK", "BCLAF1", "BCR", "BET1", "BLM", "BLMH", "BLVRA", "BOP1", "BPHL", "BPNT1", "BRCA1", "BRD1", "BRIP1", "BRIX1", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CABIN1", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CASP8AP2", "CAST", "CBL", "CBR1", "CBX4", "CCAR1", "CCAR2", "CCNB1", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD276", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC6", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK7", "CDK9", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CEP170", "CEP250", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHM", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIT", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLK2", "CLK3", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNP", "COA3", "COASY", "COCH", "COG4", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2L", "COX7C", "CPD", "CPE", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSE1L", "CSGALNACT2", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC22", "CWC27", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DBI", "DBN1", "DBNL", "DBT", "DCAF13", "DCAKD", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DEK", "DENR", "DERL1", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4ENIF1", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "ENO2", "ENTPD7", "ENY2", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERH", "ERI1", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "FAHD1", "FAM3C", "FAM98A", "FAM98B", "FARS2", "FARSA", "FARSB", "FAT1", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALE", "GALK1", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GDPD1", "GFPT1", "GGH", "GGT7", "GID8", "GLA", "GLB1", "GLB1L2", "GLDC", "GLE1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HERC2", "HERC5", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK2", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "IAH1", "IARS", "IARS2", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "ISCU", "ISOC1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "KANK2", "KARS", "KAT5", "KAT7", "KATNA1", "KCTD10", "KCTD12", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDM5B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIF11", "KIF14", "KIF15", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFAP3", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L1RE1", "L2HGDH", "L3MBTL2", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LCMT2", "LDB1", "LDHA", "LDHB", "LDLR", "LENG8", "LETM1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN2", "LMAN2L", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRIG1", "LRIG2", "LRP1", "LRPAP1", "LRR1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTN1", "LYAR", "LYPLA1", "LYPLA2", "LZTFL1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MANBA", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MBLAC2", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED27", "METAP2", "METTL13", "METTL15", "METTL17", "METTL7B", "MFAP1", "MFGE8", "MFSD3", "MFSD5", "MGA", "MGAT2", "MGEA5", "MGRN1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKL2", "MKRN2", "MMAB", "MMS19", "MOB4", "MOCS3", "MOGS", "MON2", "MORF4L1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTIF2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCDN", "NCEH1", "NCKIPSD", "NCOA4", "NCOA5", "NCOR1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NENF", "NEU1", "NF1", "NF2", "NFKBIL1", "NFRKB", "NFS1", "NHP2", "NID1", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NME1", "NME2", "NME3", "NME4", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC1", "ORC2", "ORC3", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B3", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PAM", "PAN2", "PANK4", "PAPOLA", "PARG", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDXK", "PDZD8", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHC2", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHKA1", "PHKB", "PI4K2A", "PI4K2B", "PI4KA", "PI4KB", "PICALM", "PIK3C2A", "PIK3R2", "PIK3R4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNP", "PNPLA6", "PNPT1", "PODXL", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKACB", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN23", "PTPRF", "PUF60", "PUM1", "PURA", "PURB", "PUS1", "PWP1", "PXMP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABAC1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1CC1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "RELA", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIOK2", "RIPK1", "RNASEH2A", "RNF14", "RNF31", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SALL2", "SAMHD1", "SAP130", "SAP18", "SAP30", "SAP30BP", "SARM1", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL1", "SCYL2", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC63", "SEH1L", "SELENBP1", "SELENOI", "SENP3", "SENP6", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGSH", "SHMT1", "SHMT2", "SHPRH", "SIAE", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A14", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A6", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC6", "SMG1", "SMG6", "SMN1*", "SMNDC1", "SMPD4", "SMPDL3A", "SMPDL3B", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX25", "SNX27", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORL1", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPOUT1", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STK3", "STK4", "STOM", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYDE1", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARBP1", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRD7", "TDRKH", "TECR", "TERF2IP", "TES", "TFB1M", "TFCP2", "TFG", "TFRC", "TGOLN2", "TGS1", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM17A", "TIMM23", "TIMM44", "TIMM9", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM38B", "TMEM87A", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMX2", "TMX3", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1B", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPX2", "TRAF2", "TRAP1", "TRAPPC4", "TRIM21", "TRIM24", "TRIM26", "TRIM33", "TRIO", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2B", "TRMT5", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTK", "TTLL4", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBP1", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UCK2", "UFL1", "UGCG", "UGDH", "UGGT1", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNG", "UPF2", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP32", "USP33", "USP34", "USP36", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP3", "UTP6", "UXS1", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VDAC1", "VDAC2", "VDAC3", "VKORC1L1", "VLDLR", "VMP1", "VPS11", "VPS13A", "VPS13C", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "VTI1B", "WARS", "WASF2", "WASHC5", "WDHD1", "WDR1", "WDR74", "WDR82", "WIZ", "WNK1", "WNK2", "WRN", "WRNIP1", "WWP2", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YAP1", "YARS", "YARS2", "YEATS2", "YLPM1", "YME1L1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H15", "ZC3H4", "ZC3H7B", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF131", "ZNF277", "ZNF280C", "ZNF281", "ZNF326", "ZNF598", "ZNF622", "ZNF644", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCC1", "ABCD4", "ACP2", "ADGRE5", "ADI1", "AIFM1", "ALG5", "APLP2", "APP", "ARSA", "ASAH1", "ATP1B1", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP7A", "ATRN", "B3GAT3", "B4GALT3", "B4GAT1", "BTN2A1", "CALM3", "CALU", "CANT1", "CCNB1", "CD320", "CHKA", "CHMP3", "CHPF2", "CLCN3", "CLSTN3", "COLEC12", "CPVL", "CRTAP", "CSGALNACT2", "CSNK2B", "CTSA", "CTSB", "CTSC", "CTSL", "CUTA", "CYB5B", "CYB5D2", "CYP20A1", "CYP51A1", "DAG1", "DCTPP1", "DSC3", "ECE1", "EGFR", "EHD1", "EHD4", "EPHA2", "EPHA7", "FAT1", "FCGRT", "FECH", "FUCA2", "FXR1", "FXR2", "GALNS", "GALNT1", "GALNT7", "GGH", 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10.856796116504857 0.6548503739556798 0.3454832165784889 1.4749994208625692 1.2546524785480109 1.099568757577031 0.2732488393636652 0.008459922663953 5.941460259222129e-05 0.000440337804097 0.0061570039439817 0.0062187451165004 +Extracellular structure 3 9 2.033638116747321 0.0419880957471536 2.842233009708738 8.092233009708737 0.8560017356043709 0.3472532488838395 1.4285109580808126 1.0866524100509705 0.962827743376652 0.290186194394739 0.1555278412167982 0.1201219647894398 0.2223047329091382 0.1292409073430241 0.0349002560689848 +Lipase 1 7 1.9807215044858577 0.04762251379408 1.3980582524271843 5.075242718446602 -0.1568413865531176 0.2870211072037147 0.9252636026942443 1.467005631758797 1.4600847921937092 0.2541679924186693 0.1555278412167982 1.0 0.2223047329091382 0.1292409073430241 0.3612095837488158 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..029359d332801d74e74e358b9d362a524a92ca30 --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 2314, + "title": "Average number of proteins per term", + "value": 3.140017286084702 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ecb2ee29d9b89c47e97e2b0417e23ba6ea9f6948 --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..cdec5ac0675e7b8bc60dab9398b4218520ab7fc4 --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,74 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cysteine protease 0.6276062385055117 2.7705307236361687 0.0055965020098676 0.9999977093607514 0.142674965207517 48 Q99538,P07711,P53634,P07858,Q8NHP8,Q13510,Q92820 7 +SNARE protein 0.8291865662541308 2.7231057650918147 0.0064671350169067 0.9999996982147769 0.142674965207517 14 O43752,Q9P2W9,Q86Y82,O00161,O95249,Q9UNK0,O15400,O95721,P51809,Q5SQN1,Q9UEU0 11 +Membrane trafficking regulatory protein 0.6895330664092719 2.4999939406723373 0.0124195430725932 0.999999999999724 0.142674965207517 22 Q15833,P13473,P24390,Q9H270,O00560,P11279,O43760 7 +Protease inhibitor 0.7440961334356764 2.489867413728362 0.0127790757676224 0.9999999999998812 0.142674965207517 16 P27105,Q06481,Q7KYR7,O75882,P05067,Q5ZPR3 6 +Receptor 0.5908839086617722 2.3896818234540755 0.0168629746055739 1.0 0.142674965207517 39 O43405,P15260,O75787,P20645,A6NIH7,Q14118,O94898,P11717,Q8WTV0,Q6AZY7,Q14108,Q13641 12 +Hydrolase 0.5689709325873685 2.382523038192118 0.0171944560567107 1.0 0.142674965207517 120 Q92485,Q9UMR5,Q9HAT2,Q9NX62,P15586,P11117,P16278,P34059,P50897,P15289,P06865,Q9NYA4,Q92484,O00462,P10253,P07686,P38571,Q16537,P51688,Q9Y6X5,Q8NCC3,Q99519,Q08431 23 +SLC superfamily of solute carriers 0.5640685498017854 2.3317205303347164 0.0197153980518769 1.0 0.142674965207517 51 Q9H2D1,Q8TB61,Q9H2J7,Q96QD8,Q9BXP2,Q9Y619,Q8IXU6,P08195,P30825,P41440,Q92581,Q15043,Q7L0J3,Q9Y6M7 14 +TK group 0.8198355662143418 2.1863750752917324 0.0287881755976573 1.0 0.1473624613964953 8 P29317,P23458,Q15375,P00533,P07947 5 +Esterase 0.7248909813373678 2.1407606943823394 0.032293341162199 1.0 0.1535397140500326 13 Q9UMR5,Q9HAT2 2 +Extracellular structure 0.7672521127267236 2.033638116747321 0.0419880957471536 1.0 0.1674091323107551 9 Q5KU26,O75718,Q32P28 3 +Lipase 0.7888990446291353 1.9807215044858577 0.04762251379408 1.0 0.1800629034632371 7 Q8NCC3 1 +Oxygenase 0.813894228981878 1.9341703924367497 0.0530921813790732 1.0 0.187681711885954 6 P19021 1 +Calcium-binding protein 0.5943553360055229 1.8790871513787928 0.0602325942399484 1.0 0.1982406728544486 21 Q14257,Q15293,P80303,P43307,Q9BQT9,P31949,P0DP25,O43852,Q02818 9 +Oxidase 0.5753996201159524 1.7174743207888623 0.0858925424551724 1.0 0.2429771922264901 20 O75845,Q6ZRP7,O43169,Q15800,O15260 5 +Phosphatase 0.5069569825268662 1.7016549101759204 0.0888200775753367 1.0 0.2455551487566656 34 Q9NQZ7,O43681,Q9NYA4,P22413,Q86YN1,Q13614,Q9NX62,P10586,Q9Y6X5,P11117,Q16537,Q8IWA4 12 +G-protein coupled receptor 0.9575611066344348 1.643490208836848 0.100281549500246 1.0 0.2637012150494726 2 Q5VW38 1 +P-type ATPases 0.6796739204163375 1.636031685546445 0.1018329561326087 1.0 0.2653620050572711 9 P54709,Q04656,P98194,P05026,P16615 5 +Chloride channel family 0.9500402900886432 1.6127277104972766 0.1068036774892533 1.0 0.2727855515564373 2 P51790 1 +Eph family 0.946011281224822 1.5962427046369323 0.1104346165715912 1.0 0.2771645366015858 2 Q15375 1 +Glycosidase 0.9492508056782024 1.579516523420398 0.114217629549731 1.0 0.2826733633990135 3 P06865 1 +Ion channel 0.6515692650600086 1.568104867445725 0.1168566607900249 1.0 0.2864473655382604 10 Q96RD7,Q9C0H2,P51790,P51798 4 +SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) 0.9344614558152076 1.5489734721423427 0.1213880972435239 1.0 0.2922470772898765 2 P30825 1 +Kinase activator 0.7211472448242713 1.544471038735206 0.1224742620477679 1.0 0.2936843962471864 6 Q93100 1 +SLC35 family of nucleotide sugar transporters 0.929358044587698 1.5280846484292956 0.126491522493092 1.0 0.2987310840391639 2 Q8IXU6 1 +Cell adhesion 0.6815983955794263 1.5125963355554004 0.1303822255701923 1.0 0.3053688967301872 7 P43121,Q14574,Q14126 3 +Phosphatase inhibitor 0.6641539705805762 1.4977376466981174 0.1342014266363804 1.0 0.3108529541907752 8 Q99733,P55209,P39687 3 +Protease 0.4797090892492842 1.451392404240883 0.1466706236303225 1.0 0.3247806919431257 123 Q99538,O14773,Q9UIQ6,P07711,P42892,P42785,P07858,P53634,Q9HB40,Q8NHP8,Q13510,Q9H3G5,O75844,P02786,Q92820,Q9Y6M1,P10619,Q9UBX1 18 +Cadherin 0.90491539081387 1.4280795587069943 0.1532689603959385 1.0 0.3339589212393613 2 Q14574 1 +Calmodulin 0.5465259699165038 1.403727924056153 0.1603998838949287 1.0 0.3421098180001993 16 Q14257,Q15293,P80303,P31949,P0DP25,O43852,Q02818 7 +Intracellular calcium-sensing protein 0.5465259699165038 1.403727924056153 0.1603998838949287 1.0 0.3421098180001993 16 Q14257,Q15293,P80303,P31949,P0DP25,O43852,Q02818 7 +Nucleotide phosphatase 0.5999551333212072 1.3797375465550612 0.1676674679811207 1.0 0.3511154035369352 11 Q9NQZ7,P22413,Q9Y6X5,O43681 4 +Galactosidase 0.8960236432025772 1.3779567413912637 0.1682166445030739 1.0 0.3513116564802465 3 P16278,O00462 2 +Phosphodiesterase 0.8868434502336572 1.343201558804915 0.1792067170643114 1.0 0.3634393893837131 3 Q92485 1 +Tubulin 0.7337477658983322 1.3110557913124314 0.1898389151782589 1.0 0.377070600620164 4 P07437,Q9BVA1 2 +Immunoglobulin superfamily cell adhesion molecule 0.8589846897663169 1.240948257554962 0.2146248639779608 1.0 0.4050913011786309 2 P43121 1 +Serine protease 0.4610874274884396 1.2306808612396902 0.2184422489238509 1.0 0.4096234716448873 30 O14773,P42785,Q9HB40,Q9H3G5,Q9Y6M1,P10619 6 +SLC12 family of cation-coupled chloride transporters 0.8495432563138079 1.2023721714693427 0.2292193660914638 1.0 0.4209631850282915 3 Q9BXP2,P55011 2 +PKA family 0.848240666129476 1.1974681227794273 0.2311241451756216 1.0 0.4231180948863833 2 P22694 1 +Glycosyltransferase 0.4687981583314687 1.1850946250429977 0.2359800360022363 1.0 0.4282806300464117 25 Q86SF2,Q8N128,Q9P2E5,Q10472,O60512,Q8N6G5,Q16739,O94766,Q10469,Q9Y2G5 10 +Ca2+-ATPases 0.6785810266057355 1.0872180362958306 0.2769404616415447 1.0 0.4729448178882173 4 P20020,P98194,P16615 3 +Lipid kinase 0.560906953354732 0.9680619171760424 0.3330134478117847 1.0 0.5261086544510386 7 Q9BTU6 1 +Heterotrimeric G-protein 0.5488848478185224 0.9633521429861382 0.3353708341352515 1.0 0.5279238844822939 8 P08754,P09471,Q14344,P04899,P63096,P29992 6 +SLC4 family of bicarbonate transporters 0.7816277195810032 0.9328081777224108 0.3509190181693884 1.0 0.5419126693302381 2 Q9Y6M7 1 +ABCB subfamily 0.5793801873661143 0.9325567503595223 0.3510488726560186 1.0 0.5419126693302381 6 P08183,Q03519 2 +Protein phosphatase 0.5110673616147343 0.9281714483012508 0.3533186423475585 1.0 0.5440842880482516 11 Q16537 1 +Phosphatase modulator 0.5070224760405564 0.8594733361818606 0.3900794245635208 1.0 0.572017609911272 10 Q99733,P55209,P39687 3 +MST subfamily 0.7166263765780273 0.6891051586073745 0.4907570939600307 1.0 0.6505259273248286 2 Q13188 1 +Signaling 0.4043615787197718 0.628064667987667 0.5299615775257296 1.0 0.6782327433913621 20 Q8WUJ1,Q07820,O15173,Q96PC5 4 +Na+/K+-ATPases 0.6883396023643146 0.6233280753982876 0.533068951903064 1.0 0.6800008570582636 3 P54709,P05026 2 +Methyltransferase 0.415031486696745 0.6219183449392263 0.5339955617195709 1.0 0.6800581892234931 16 P21964,Q9BV86,Q08J23 3 +G-protein 0.3767808431848545 0.6044246188965086 0.5455613720648653 1.0 0.6909846825167478 31 P11233,P08754,P09471,Q8NHH9,P61225,P50570,O00429,Q9NTK5,Q14344,Q05193,Q8IXI2,P04899,Q15019,P63096,P29992 15 +Metalloprotease 0.365042430758155 0.5756320694527627 0.5648638998557716 1.0 0.7014244181310898 40 P02786,Q9UIQ6,P42892 3 +ATP-binding cassette transporter family 0.4485460997571975 0.5437954493832912 0.5865822406496357 1.0 0.7143954236122405 9 P08183,Q03519,P33527 3 +Enzyme modulator 0.4099577882299126 0.5271878169177259 0.5980631681776085 1.0 0.7204154977423145 136 P55209,Q14344,Q12893,Q99733,Q9Y3E7,P63096,P46379,Q9H223,P05067,Q9Y2I1,Q9H4M9,P11233,P53365,Q01105,Q96ED9,Q06481,P04899,Q7KYR7,P29992,Q5ZPR3,P08754,P09471,O00429,Q9NTK5,Q9H3E2,P14635,O00459,P07942,Q9H0H5,P27105,Q9UNN8,Q93100,P39687,O75882 34 +Protein methyltransferase 0.4035712786681709 0.3957597205906796 0.6922822940868956 1.0 0.7776413730665419 11 Q96KQ7 1 +V-type ATPase 0.4212686786199526 0.3939784154066141 0.6935969751391693 1.0 0.7779851674609974 8 Q93050 1 +Transporter 0.4798333975642833 0.3188800330471625 0.7498174858577231 1.0 0.8005296865625329 218 Q93050,Q9BQE5,Q99523,Q8TB61,Q96QD8,Q9H6H4,P13473,Q9H270,O15400,Q9Y487,P55011,P17900,Q9UEU0,Q96NB2,Q9BVK6,Q9HD45,Q99805,P33527,Q13190,O95249,Q9UHQ4,Q92673,Q9Y666,Q8WU76,P24390,P51809,P11166,O95721,P54920,Q9P2W9,Q9H2D1,Q86Y82,Q04656,P98194,Q5SQN1,P11279,P05026,O43493,Q15043,P41440,Q7L0J3,O43752,Q99808,Q15833,Q9H2J7,O00161,O14678,Q9BXP2,Q9UNK0,Q9Y619,O00560,P30825,P08195,Q92544,Q92581,O43760,Q8IXU6,Q9Y6M7 58 +Reductase 0.3586488986380045 0.3059562009606535 0.7596379941586664 1.0 0.8048545414300156 17 O95881,Q9UBM7,P00374,Q15392 4 +Writer 0.3708012388820158 0.2713666996993724 0.7861090112149387 1.0 0.8190257775557713 12 Q96KQ7 1 +Serine protease inhibitor 0.5118216012896196 0.170145617457151 0.8648956189617467 1.0 0.8770238660286949 3 P50454,P30740 2 +PDHK family 0.5099408919935428 0.1670685346563512 0.8673161237208702 1.0 0.8790930837889153 3 Q15120,O14874 2 +CK1 group 0.3963988175221742 0.1519758304886505 0.8792059986739766 1.0 0.890754238586507 4 Q8IV63,P48729,Q86Y07 3 +HDAC class I 0.5073865162503334 0.1460412512113769 0.8838888237521298 1.0 0.8943238907575113 2 Q13547 1 +Guanyl-nucleotide exchange factor 0.3567204301075202 0.1141842483677334 0.9090917382184076 1.0 0.91902065628545 5 Q14C86,Q96N67,Q96HP0,Q9Y4G8 4 +G-protein modulator 0.3065712663374591 0.1096570318396311 0.912681378462462 1.0 0.9222465981494048 36 Q9H4M9,P53365,Q9H3E2,Q12893,Q86VI3,Q9H223,Q9H0H5 7 +Histone deacetylase 0.3681805966138134 0.1047515688215198 0.9165729410131412 1.0 0.9257746772171142 4 Q13547,Q92769,Q8IXJ6 3 +Acyltransferase 0.334356300747932 0.096816987525493 0.9228717332165112 1.0 0.9317300133782752 10 Q9UJ14 1 +Cytokine 0.4469513832930239 0.085857555046036 0.9315796530313494 1.0 0.9397015331798354 2 P43490 1 +MLK family 0.4305667472468421 0.0759583857750011 0.9394522058465338 1.0 0.94681724927216 2 Q13418 1 +HDAC class III 0.3679828095621854 0.0553684348569279 0.9558449425821962 1.0 0.962081425461158 2 Q8IXJ6 1 +VRK family 0.396292315959152 0.0526139244661077 0.9580395222187152 1.0 0.9638710671365682 3 Q8IV63,Q86Y07 2 +Mitochondrial di- and tri-carboxylic acid transporter subfamily 0.2536952432141883 0.0164435706019712 0.9868805201264574 1.0 0.992456116285364 4 Q02978,P53007,Q9UBX3 3 +TKL group 0.2219833378124076 0.0110401399148068 0.9911914217517062 1.0 0.9963583622647472 4 O43318,P10398,Q13418 3 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c949dc3bd49dc5de5a582e0b92a312bfc2b588ca --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1,4-alpha-glucan-branching enzyme", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial", "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S24, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3'-5' exoribonuclease 1", "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L16, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L23, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L41, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S26", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-1", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AF4/FMR2 family member 4", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMP deaminase 2", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-1 complex subunit sigma-2", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "AT-rich interactive domain-containing protein 3B", "AT-rich interactive domain-containing protein 4B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP synthase-coupling factor 6, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family B member 8, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family D member 4", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase WRNIP1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "AUR family", "Abl interactor 1", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A transporter 1", "Acetyltransferase", "Acid ceramidase", "Acid sphingomyelinase-like phosphodiesterase 3a", "Acid sphingomyelinase-like phosphodiesterase 3b", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 2/3 complex subunit 5", "Actin-related protein 3", "Activating signal cointegrator 1", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-CoA-binding protein", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Adenylyltransferase and sulfurtransferase MOCS3", "Adhesion class", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine aminotransferase 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose reductase", "Alpha-1,2-mannosyltransferase ALG9", "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amylase", "Amyloid-beta A4 protein", "Amyloid-like protein 2", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Angiotensin-converting enzyme 2", "Anion channel tweety (tweety) family", "Anion exchange protein 2", "Anion exchangers", "Ankyrin repeat and SAM domain-containing protein 1A", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Antigen peptide transporter 2", "Ap2-associated protein kinase 1", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arfaptin-2", "Arginase-2, mitochondrial", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Arylsulfatase A", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atlastin-3", "Atp-dependent 6-phosphofructokinase, liver type", "Attractin", "Atypical SLC22B subfamily", "Atypical group", "Aurora kinase a", "Aurora kinase b", "B-cell receptor-associated protein 29", "B-cell receptor-associated protein 31", "BET1 homolog", "BTB/POZ domain-containing protein KCTD12", "BUB family", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2 homologous antagonist/killer", "Bcl-2-associated transcription factor 1", "Beta-1,4-galactosyltransferase 3", "Beta-adducin", "Beta-galactosidase", "Beta-galactosidase-1-like protein 2", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Beta-mannosidase", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "Bifunctional coenzyme A synthase", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biotin--protein ligase", "Bis(5'-adenosyl)-triphosphatase ENPP4", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, cytosolic", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breakpoint cluster region protein", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 3", "Bromodomain-containing protein 4", "Butyrophilin subfamily 2 member A1", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CASK family", "CASP8-associated protein 2", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 2", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CD276 antigen", "CD97 antigen", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK7 subfamily", "CDK9 subfamily", "CDKN2A-interacting protein", "CHK1 subfamily", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CLK family", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "COUP-TF-like receptors", "CRK7 subfamily", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcineurin-binding protein cabin-1", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calsyntenin-3", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Camp-dependent protein kinase catalytic subunit beta", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carnitine O-acetyltransferase", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-8", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cathepsin B", "Cathepsin F", "Cathepsin L1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell division cycle protein 20 homolog", "Cell surface glycoprotein MUC18", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Centrosome-associated protein CEP250", "Ceramide glucosyltransferase", "Chaperone", "Chaperonin", "Charged multivesicular body protein 3", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Chondroitin sulfate N-acetylgalactosaminyltransferase 2", "Chondroitin sulfate glucuronyltransferase", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 2", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "Citron rho-interacting kinase", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain A", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cochlin", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collagen type IV alpha-3-binding protein", "Collectin-12", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Copper-transporting ATPase 1", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Coronin-7", "Coup transcription factor 1", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cu+-ATPases", "Cullin-1", "Cullin-2", "Cullin-4A", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-K", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent kinase 7", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytokine receptor", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "DDB1- and CUL4-associated factor 13", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA polymerase subunit gamma-1", "DNA primase small subunit", "DNA repair endonuclease XPF", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA topoisomerase 3-alpha", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase III subunit RPC5", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 6", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(14)-sterol reductase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxycytidylate deaminase", "Deoxyribonuclease-2-alpha", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 4", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Diphthine methyl ester synthase", "Disks large homolog 1", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Down syndrome critical region protein 3", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity protein kinase clk2", "Dual specificity protein kinase clk3", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "Dystroglycan", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase DTX3L", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase MGRN1", "E3 ubiquitin-protein ligase NEDD4", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase RNF14", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EF-hand domain-containing protein D1", "EGFR family", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELKS/Rab6-interacting/CAST family member 1", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "ERO1-like protein beta", "Early endosome antigen 1", "Ectonucleoside triphosphate diphosphohydrolase 7", "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Endodeoxyribonuclease", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelial protein C receptor", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 2", "Ephrin type-a receptor 7", "Epidermal growth factor receptor", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Ethanolaminephosphotransferase 1", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 1", "Exocyst complex component 3", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 6B", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exostosin-2", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "Fanconi anemia group J protein", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferritin light chain", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Folate transporter 1", "Forkhead box protein C1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GDP-fucose protein O-fucosyltransferase 2", "GEK subfamily", "GHMP kinase family", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GPN-loop GTPase 1", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-enolase", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "Gap junction-forming innexin (innexin) family", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General transcription factor IIH subunit 1", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucose-induced degradation protein 8 homolog", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase catalytic subunit", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamine-rich protein 1", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione hydrolase 7", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi SNAP receptor complex member 2", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein G(o) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-11", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "H/ACA ribonucleoprotein complex subunit 3", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histidine triad nucleotide-binding protein 3", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone deacetylase complex subunit SAP30", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase NSD3", "Histone-lysine N-methyltransferase SETD2", "Histone-lysine N-methyltransferase SMYD3", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Homeobox protein CDX-2", "Homeodomain transcription factor", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Huntingtin-interacting protein 1", "Huntingtin-interacting protein 1-related protein", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "INSR family", "ITPK1 family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive serine/threonine-protein kinase vrk3", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 1", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Inositol-tetrakisphosphate 1-kinase", "Insulin-degrading enzyme", "Insulin-like growth factor 1 receptor", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon gamma receptor 1", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intersectin-2", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "JAKA family", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Katanin p60 ATPase-containing subunit A1", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-associated protein 3", "Kinesin-like protein KIF11", "Kinesin-like protein KIF14", "Kinesin-like protein KIF15", "Kinesin-like protein KIF18B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIF7", "Kinesin-like protein KIFC1", "Kinetochore protein NDC80 homolog", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LIM domain-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lactadherin", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Laminin subunit gamma-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Legumain", "Lethal(2) giant larvae protein homolog 1", "Lethal(3)malignant brain tumor-like protein 2", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucine-rich repeats and immunoglobulin-like domains protein 1", "Leucine-rich repeats and immunoglobulin-like domains protein 2", "Leucyl-cystinyl aminopeptidase", "Leukocyte elastase inhibitor", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific demethylase 5B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "M-phase phosphoprotein 8", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 3", "MAPK family", "MARK subfamily", "MAX gene-associated protein", "MCU family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "MSN subfamily", "MST subfamily", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA", "Mediator of RNA polymerase II transcription subunit 12", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 21", "Mediator of RNA polymerase II transcription subunit 25", "Mediator of RNA polymerase II transcription subunit 27", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D1", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Metallo-beta-lactamase domain-containing protein 2", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine--tRNA ligase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Methyltransferase-like protein 7B", "Mevalonate kinase", "Mevalonate kinase subfamily", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial cardiolipin hydrolase", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitogen-activated protein kinase kinase kinase 4", "Mitogen-activated protein kinase kinase kinase 7", "Mitogen-activated protein kinase kinase kinase kinase 4", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multidrug resistance-associated protein 4", "Multifunctional protein ADE2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 2", "Myotubularin-related protein 4", "Myotubularin-related protein 6", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2", "N-acetyl-D-glucosamine kinase", "N-acetylgalactosamine-6-sulfatase", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "N-alpha-acetyltransferase 50", "N-sulphoglucosamine sulphohydrolase", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "N-terminal kinase-like protein", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NAD-dependent protein deacetylase sirtuin-2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD4-like E3 ubiquitin-protein ligase WWP2", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NLR family member X1", "NRBP family", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neural Wiskott-Aldrich syndrome protein", "Neurofibromin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neuroplastin", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral amino acid transporter subfamily", "Neutral cholesterol ester hydrolase 1", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear factor related to kappa-B-binding protein", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor", "Nuclear receptor coactivator 4", "Nuclear receptor coactivator 5", "Nuclear receptor corepressor 1", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin GLE1", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase 3", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside diphosphate kinase, mitochondrial", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "NudC domain-containing protein 3", "OCIA domain-containing protein 1", "Obg-like ATPase 1", "Occludin", "Origin recognition complex subunit 1", "Origin recognition complex subunit 2", "Origin recognition complex subunit 3", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PAN2-PAN3 deadenylation complex catalytic subunit PAN2", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 14", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PITSLRE subfamily", "PKA family", "PKC alpha subfamily", "PKC delta subfamily", "PKC family", "PKN family", "PLK family", "PMS1 protein homolog 1", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pannexin-1", "Pantothenate kinase 4", "Paraspeckle component 1", "Paxillin", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-glycine alpha-amidating monooxygenase", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 3", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal bifunctional enzyme", "Peroxisomal biogenesis factor 19", "Peroxisomal carnitine O-octanoyltransferase", "Peroxisomal leader peptide-processing protease", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phenylalanine--tRNA ligase, mitochondrial", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 3-kinase regulatory subunit beta", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-kinase type 2-beta", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phospholipid-transporting ATPase IG", "Phospholipid-transporting ATPases", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphoribosyltransferase domain-containing protein 1", "Phosphorylase", "Phosphorylase b kinase regulatory chain family", "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform", "Phosphorylase b kinase regulatory subunit beta", "Phosphorylated adapter RNA export protein", "Phosphotriesterase-related protein", "Pirin", "Plakophilin-2", "Plasma membrane calcium-transporting ATPase 1", "Plasma membrane calcium-transporting ATPase 4", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polyhomeotic-like protein 2", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polypeptide N-acetylgalactosaminyltransferase 4", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SLU7", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Prenylated Rab acceptor protein 1", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX34", "Probable ATP-dependent RNA helicase DHX35", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable E3 ubiquitin-protein ligase makorin-2", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable cysteine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable helicase with zinc finger domain", "Probable histidine--tRNA ligase, mitochondrial", "Probable leucine--tRNA ligase, mitochondrial", "Probable methyltransferase-like protein 15", "Probable ribosome biogenesis protein RLP24", "Probable serine carboxypeptidase CPVL", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein ABHD16A", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein FAM177A1", "Protein Hook homolog 2", "Protein LSM14 homolog B", "Protein Mpv17", "Protein NDRG3", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein S100-A13", "Protein SCAF8", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SET", "Protein VAC14 homolog", "Protein Wiz", "Protein angel homolog 1", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein kinase c alpha type", "Protein kinase c delta type", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein strawberry notch homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec23B", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog A", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RAF family", "RIO family", "RIO2 subfamily", "RIPK family", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA polymerase II elongation factor ELL", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein with serine-rich domain 1", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab proteins geranylgeranyltransferase component A 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 6", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras GTPase-activating-like protein IQGAP3", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein R-Ras2", "Ras-related protein Ral-A", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Receptor-type tyrosine-protein phosphatase F", "Recombining binding protein suppressor of hairless", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Rel homology transcription factor", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p25-like protein", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribonucleoside-diphosphate reductase subunit M2 B", "Ribose-phosphate pyrophosphokinase 1", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal RNA-processing protein 7 homolog A", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "SAP30-binding protein", "SCY1 family", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC22 family of organic cation and anion transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC33 acetylCoA transporter", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC39 family of metal ion transporters", "SLC4 family of bicarbonate transporters", "SLC5 family of sodium-dependent glucose transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC6 neurotransmitter transporter family", "SLC61 Molybdate transporter family", "SLC7 family", "SLC9 family of sodium/hydrogen exchangers", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STE group", "STE11 family", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "Sal-like protein 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class A member 3", "Scavenger receptor class B member 1", "Scy1-like protein 2", "Sec1 family domain-containing protein 1", "Sec1 family domain-containing protein 2", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Secretory carrier-associated membrane protein 4", "Segment polarity protein dishevelled homolog DVL-2", "Selenide, water dikinase 1", "Sentrin-specific protease 3", "Sentrin-specific protease 6", "Separin", "Septin-2", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine-protein kinase atm", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 2", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase 3", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase a-raf", "Serine/threonine-protein kinase chk1", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mrck beta", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase rio2", "Serine/threonine-protein kinase smg1", "Serine/threonine-protein kinase ulk3", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein kinase wnk2", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialate O-acetylesterase", "Sialic acid synthase", "Sialidase-1", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal recognition particle 14 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters", "Sodium-coupled neutral amino acid transporter 2", "Sodium-dependent HCO3- transporters", "Sodium-dependent multivitamin transporter", "Sodium-dependent neutral amino acid transporter B(0)AT2", "Sodium/hydrogen exchanger 6", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 7", "Solute carrier family 12 member 9", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 25 member 44", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sortilin", "Sortilin-related receptor", "Sorting nexin-1", "Sorting nexin-2", "Sorting nexin-25", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Sphingosine kinase 2", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptic vesicle glycoprotein 2A", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 23", "Synaptosomal-associated protein 29", "Synaptosomal-associated protein 47", "Syntaxin-12", "Syntaxin-18", "Syntaxin-5", "Syntaxin-6", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 2", "Syntaxin-binding protein 3", "Syntenin-1", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TAK1 subfamily", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 10B", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TNF receptor-associated factor 2", "TOPK family", "TP53-binding protein 1", "TRIO family", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Testis-specific Y-encoded-like protein 1", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid adenoma-associated protein", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tmem38 family", "Torsin-1B", "Trafficking protein particle complex subunit 4", "Trans-Golgi network integral membrane protein 2", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription factor 20", "Transcription factor p65", "Transcription initiation factor IIB", "Transcription initiation factor TFIID subunit 9B", "Transcriptional activator protein Pur-alpha", "Transcriptional activator protein Pur-beta", "Transcriptional coactivator YAP1", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transducin-like enhancer protein 3", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 4", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 115", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-2", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Trimeric intracellular cation channel type B", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Triple functional domain protein", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2B chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin polyglutamylase TTLL4", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tudor domain-containing protein 7", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinfilin-2", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type II cytokine receptor", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase jak1", "Tyrosine-protein kinase yes", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein IMP4", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm3", "U6 snRNA-associated Sm-like protein LSm4", "U6 snRNA-associated Sm-like protein LSm5", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "U6 snRNA-associated Sm-like protein LSm8", "UDP-glucose:glycoprotein glucosyltransferase 1", "UDP-glucuronic acid decarboxylase 1", "ULK family", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog A", "UV excision repair protein RAD23 homolog B", "UbiA prenyltransferase domain-containing protein 1", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 22", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 33", "Ubiquitin carboxyl-terminal hydrolase 34", "Ubiquitin carboxyl-terminal hydrolase 36", "Ubiquitin carboxyl-terminal hydrolase 38", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase BAP1", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like modifier-activating enzyme ATG7", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Unconventional myosin-Va", "Upstream-binding protein 1", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VIP36-like protein", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 11 homolog", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Vacuolar protein sorting-associated protein 72 homolog", "Vacuole membrane protein 1", "Very long-chain acyl-CoA synthetase", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle transport through interaction with t-SNAREs homolog 1B", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WASH complex subunit 5", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WEE family", "WNK family", "Werner syndrome ATP-dependent helicase", "Winged helix/forkhead transcription factor", "Wiskott-Aldrich syndrome protein family member 2", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YLP motif-containing protein 1", "YSK subfamily", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7B", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger and BTB domain-containing protein 10", "Zinc finger protein 277", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein 644", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 5", "Zinc transporter ZIP14", "Zyxin", "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial", "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-decapping enzyme 1A", "mRNA-decapping enzyme 1B", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine(37)-N1)-methyltransferase", "tRNA pseudouridine synthase A"], "available_proteins": ["AAK1", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD16A", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACE2", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG9", "ALYREF", "AMPD2", "ANAPC1", "ANGEL1", "ANKS1A", "ANO6", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APLP2", "APOL2", "APP", "ARAF", "ARCN1", "ARFIP1", "ARFIP2", "ARG2", "ARHGDIA", "ARID3B", "ARID4B", "ARIH1", "ARPC1A", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARVCF", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATM", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATRN", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GALT3", "BAG6", "BAIAP2", "BAK1", "BAP1", "BCAP29", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCKDHB", "BCKDK", "BCLAF1", "BCR", "BET1", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CABIN1", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CASP8AP2", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD276", "CD2BP2", "CDC20", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK7", "CDK9", "CDKN2AIP", "CDX2", "CEBPZ", "CEP170", "CEP250", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHKA", "CHM", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHUK", "CIRBP", "CIT", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLK2", "CLK3", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNP", "COASY", "COCH", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CRNKL1", "CROT", "CRTAP", "CS", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CTTN", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAP3", "DARS", "DARS2", "DBI", "DBN1", "DBNL", "DBT", "DCAF13", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DDAH2", "DDB1", "DDI2", "DDOST", "DENR", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX34", "DHX35", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLG1", "DLGAP5", "DLST", "DNASE2", "DNM1", "DNM1L", "DNM2", "DNMT1", "DOCK6", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DTX3L", "DTYMK", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "ENO2", "ENPP1", "ENPP4", "ENTPD7", "EPHA2", "EPHA7", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC4", "ERH", "ERI1", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "FAHD1", "FAM177A1", "FARS2", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FOXC1", "FOXRED1", "FSCN1", "FTL", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GGT7", "GID8", "GLB1", "GLB1L2", "GLDC", "GLE1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GOSR2", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H1", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK2", "HPRT1", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFNGR1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "JAK1", "KARS", "KAT7", "KATNA1", "KCTD12", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDM5B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF11", "KIF14", "KIF15", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFAP3", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL2", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDB1", "LDHA", "LDHB", "LETM1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN2", "LMAN2L", "LNPEP", "LONP1", "LPCAT1", "LRIG1", "LRIG2", "LRRC47", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSM8", "LTN1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A1", "MANBA", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS2", "MAT2A", "MBLAC2", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME2", "MECP2", "MED12", "MED14", "MED21", "MED25", "MED27", "METTL15", "METTL7B", "MFAP1", "MFGE8", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGA", "MGAT2", "MGRN1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MKRN2", "MMS19", "MOB4", "MOCS3", "MORF4L1", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL38", "MRPL39", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL49", "MRPL9", "MRPS11", "MRPS16", "MRPS18A", "MRPS2", "MRPS24", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCEH1", "NCL", "NCOA4", "NCOA5", "NCOR1", "NDC80", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB11", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEDD4", "NEK9", "NEU1", "NF1", "NFRKB", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NLRX1", "NME1", "NME2", "NME3", "NME4", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OLA1", "OPA1", "ORC1", "ORC2", "ORC3", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "PACSIN2", "PACSIN3", "PAICS", "PAK2", "PAM", "PAN2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDHX", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4K2B", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIK3C2A", "PIK3R2", "PIK3R4", "PINX1", "PIP4K2C", "PIR", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNP", "PNPLA6", "PNPT1", "POFUT2", "POGZ", "POLD2", "POLDIP3", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL3", "PPM1G", "PPME1", "PPP1CA", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA1", "PRKAA2", "PRKACA", "PRKACB", "PRKAG1", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPRF", "PUM1", "PURA", "PURB", "PUS1", "PWP1", "PXMP2", "PXN", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "RAB3GAP2", "RABAC1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "RELA", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RIOK2", "RIPK1", "RNASEH2A", "RNF14", "RNH1", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RRM2B", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "S100A10", "S100A11", "S100A13", "SAE1", "SALL2", "SAP18", "SAP30", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SC5D", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCAMP4", "SCARA3", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCPEP1", "SCYL1", "SCYL2", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SELENOI", "SENP3", "SENP6", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SGSH", "SHMT1", "SHMT2", "SIAE", "SIN3A", "SIRT1", "SIRT2", "SKP1", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A6", "SLK", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMG1", "SMN1*", "SMPDL3A", "SMPDL3B", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX25", "SOAT1", "SOD2", "SORD", "SORL1", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPHK2", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAT1", "STAT3", "STK26", "STK3", "STK4", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX12", "STX18", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRD7", "TDRKH", "TECR", "TES", "TFCP2", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TJP1", "TK1", "TKT", "TLE3", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM38B", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOP3A", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC4", "TRIO", "TRIP4", "TRMT5", "TRMT6", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTK", "TTLL4", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UBE4B", "UBIAD1", "UBP1", "UCHL5", "UCK2", "UGCG", "UGGT1", "ULK3", "UNC119", "UNC119B", "UPF1", "UPF2", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP28", "USP33", "USP34", "USP36", "USP38", "USP39", "USP47", "USP5", "USP7", "UTP11", "UTP14A", "UTP3", "UTP6", "UXS1", "VAC14", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VMP1", "VPS11", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS72", "VRK1", "VRK2", "VRK3", "VTI1B", "WARS", "WASF2", "WASHC5", "WASL", "WDHD1", "WDR1", "WDR74", "WDR82", "WIZ", "WNK1", "WNK2", "WRN", "WRNIP1", "WWP2", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YAP1", "YARS", "YARS2", "YEATS2", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H15", "ZC3H7B", "ZCCHC11", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF277", "ZNF281", "ZNF598", "ZNF622", "ZNF644", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCC1", "ABCD4", "ACP2", "ANP32A", "APLP2", "APOL2", "APP", "ARAF", "ARFIP2", "ARSA", "ASAH1", "ASNA1", "ATL2", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP7A", "ATRN", "B3GAT3", "B4GALT3", "BAG6", "BCAP29", "BCKDK", "BTN2A1", "CALM3", "CALU", "CCNB1", "CD276", "CHMP3", "CHPF2", "CLCN3", "CLCN7", "CLSTN3", "COCH", "COLEC12", "COMT", "CPVL", "CRTAP", "CSGALNACT2", "CSNK1A1", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CYB5B", "CYB5D2", "DAG1", "DHCR24", "DHCR7", "DHFR", "DNM1", "DNM1L", "DNM2", "DOCK6", "DOCK7", "DOLPP1", "DSC3", "DSG2", "ECE1", "EGFR", "EHD1", "EHD4", "EHMT2", "ENPP1", "ENPP4", "ENTPD7", "EPHA2", "EPHA7", "FAM177A1", "GAA", "GALNS", "GALNT1", "GALNT7", "GAPVD1", "GGH", "GGT7", "GLB1", "GM2A", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNS", "GOSR1", "GPR107", "HDAC1", "HDAC2", "HEXA", "HEXB", "HOOK2", "IFNGR1", "IGF2BP2", "IGF2R", "ILK", "IMPAD1", "IQGAP3", "JAK1", "KDELR1", "LAMB1", "LAMP1", "LAMP2", "LGMN", "LIPA", "LNPEP", "LRIG2", "M6PR", "MANBA", "MAP3K7", "MCAM", "MCL1", "MFGE8", "MFN1", "MGAT2", "MIA2", "MSMO1", "MTMR2", "MTMR4", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NEU1", "NISCH", "NSUN2", "NTMT1", "NUCB1", "NUCB2", "OLA1", "P3H1", "PAM", "PANX1", "PDK3", "PGRMC2", "PHKB", "PI4K2A", "PIK3R2", "PLA2G15", "PLBD2", "POFUT2", "PPP2R5E", "PPT1", "PPT2", "PRCP", "PRKACB", "PROCR", "PTPRF", "QSOX2", "RACGAP1", "RALA", "RAP2B", "RAPGEF2", "RCN1", "RCN2", "REEP4", "RHOT1", "S100A11", "SC5D", "SCARA3", "SCARB1", "SCARB2", "SCFD2", "SCPEP1", "SDCBP", "SEPT2", "SERPINB1", "SERPINH1", "SET", "SFXN2", "SGSH", "SIAE", "SIRT2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A15", "SLC25A32", "SLC29A1", "SLC2A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A6", "SMPDL3A", "SMPDL3B", "SNAP23", "SNAP29", "SNAP47", "SNX25", "SORL1", "SORT1", "SSR1", "STK3", "STOM", "STX12", "STX18", "STX5", "STX6", "STX7", "STX8", "STXBP2", "SURF4", "SV2A", "SYNGR2", "TAP2", "TFRC", "TGOLN2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED9", "TMEM115", "TPBG", "TPP1", "TTYH3", "TUBB", "TUBB2B", "TXNDC12", "UGCG", "UNC119B", "VAMP7", "VPS11", "VRK2", "VRK3", "VTI1B", "YES1", "ZMPSTE24"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6e0847ffc649d08286e63465c7dfff7898d31ecd --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..59fc616143d1d53a7c767e89091bf519736665ad --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:959c627389d3da1c88e2b90f8950b469303fb15a83189922c69b5132c8e2e725 +size 218272 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ddd662d46a4f8971ba47d18342352a728e89ddee --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio", "1": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..69993b5be8eaa18bd034364fea06c64d5e012872 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cf35b9e1e49fe8268a5a5e325bf99113e277b8ef09aa18d2e67a42da6a2d42a2 +size 129469 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..f67df46bcff946ee91b7d676fe77b0bd65146bb7 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4ac780a01745a5a1453f9f37e35df9c8161e858eb850b20be0170a53ac1978aa +size 132545 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..1e064142dbe8ac70a15d5af9314a7c94ef6d0816 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b75f25e043846082edd6e9f108925aed94b49af333c46da65d48eb875c2a8d9c +size 91975 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6a6ef84c3c55496de9d9f3d5db2c61e8c2ecb69d --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tbio 394 2851 7.326557592986998 2.3613973915403497e-13 467.6796116504854 2434.25 -0.5416405556668178 0.3215141878443288 119.73666199244032 234.70955636597876 4.704421961664106 0.4116627836259234 0.3327168311224842 0.8024549082287908 0.7898649775330551 0.2959496839268059 0.0229050593073188 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..140a2a9b2c44f76e7c30bc417001f20643ab3cc6 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 931.0 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a705fff9fd29110ccc075e883b71cc073c6d054c --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..59ce3b36219a16eb3b4fc5d766d9cd78a56de7e3 --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tbio 0.2404171396059257 7.326557592986998 2.3613973915403497e-13 9.445629566158053e-13 9.4456295661614e-13 2851 Q9BXS4,O14773,Q9UMR5,O75629,Q9HAT2,Q9UM22,Q13501,Q9HB40,P15260,Q8NHP8,O00584,Q9Y287,Q5KU26,P13473,O00115,Q9C0H2,P07602,P15586,Q08380,O75976,P17900,Q6UXD5,O75503,P11117,P98155,Q8IV08,P34059,P50897,P54802,P61916,O43169,Q8IZA0,Q92673,Q06481,Q9BQT9,Q13772,Q86VP1,Q14108,Q01459,Q86WC4,P98164,Q9UBG0,Q9NPF0,Q92896,P04439,Q9NUM4,Q15392,O60637,Q14574,Q9NQX7,P14543,P13051,Q9H3G5,Q13423,P02786,O43657,Q9Y6X5,Q13137,P11279,Q8NCC3,Q9Y2R0,O43493,Q8N6G5,Q99519,P21796,O43752,Q8NB78,P27105,Q99595,P10321,Q08431,Q92542,O94813,Q8NBJ4,O60512,O00592,Q9UNN8,Q9HCM3,Q8NBZ7,O00560,P30825,Q6YHK3,O75882,Q07954,Q92581,Q9HCL2,O15118,Q8NHS3,Q9Y6N7,O43852,Q92485,Q9BQE5,O43505,Q8NDZ4,P01889,O00461,Q9NS69,P80303,Q16625,Q96QD8,P22830,Q14118,Q7LGA3,O60888,Q9Y6M1,P16870,Q9H6K4,Q9Y624,P48960,Q14257,Q14517,O95456,Q9UHG3,O43405,P15289,Q32P28,Q9NYA4,Q92484,Q8IUH4,Q5SZK8,A6NIH7,P43307,P10644,P24390,O60266,Q7KYR7,Q8N9N5,O15260,Q6AZY7,Q13641,Q16537,Q96G23,P02792,Q9P2W9,Q9H2D1,P51688,Q8NE01,Q08J23,Q8WVQ1,Q86Y82,Q9BUK6,Q08722,Q8NCH0,Q969R5,O75844,P67809,Q9H2C2,Q9NV96,P48723,Q2T9J0,Q9UQ84,Q15043,Q8IXM6,O60245,P53701,Q86UY6,Q9Y282,Q5SRI9,Q8TCG2,Q92804,Q92859,Q9UJ14,O95831,Q9P2E5,P20645,O60291,Q8N511,Q9BRG1,P51114,Q9UNK0,Q9Y619,Q93100,P08195,P78310,Q9NTX5,O43760,Q9H9S5,Q92692,Q9Y6M7,Q93050,Q86XL3,P43304,Q9P273,Q7Z3C6,Q8TB61,Q9P1Z2,O14979,Q9BTU6,Q9BV86,P55209,Q8IY95,O75955,O15400,Q99733,Q9Y487,P50402,Q8TAA9,Q14011,Q9H223,P31943,Q9UEU0,Q9ULH0,P17301,P35613,Q9BXW6,O75718,P11233,P53365,Q99543,Q07021,Q6ZRP7,O95772,O15460,O95249,Q14168,Q96J02,O94898,P04899,P51809,Q06136,P98179,Q8N4Q0,Q99729,Q9UNK9,Q9NQ11,Q9H2J4,Q15293,Q96QR8,Q96RD7,Q9Y5Y5,P13591,P31483,P38159,P31942,Q9BY67,Q12789,Q16740,O75787,O60506,Q04656,Q13685,Q15800,Q9H3E2,Q9Y4F1,P51116,Q68CQ7,O94766,Q6P4Q7,Q92791,Q14254,O15212,O43390,P35637,O43396,O43847,Q14126,Q96PC5,Q9NR28,Q8N0U8,Q96J84,Q9UKS6,Q00013,Q96KC8,O14678,P43121,Q06787,Q8WWV3,Q92783,Q9BTX1,Q92544,Q13049,Q6UX53,Q9NZ43,Q8TDY2,Q05086,P52597,P33908,Q86SF2,Q8TEL6,Q04446,Q96SZ5,Q9UL15,Q9Y6W5,Q6DKK2,P27544,O15173,O43823,Q9BRR6,Q4KMQ2,Q9H6H4,Q9NWW5,P22626,Q9P016,Q9Y3E7,Q7KZN9,P63096,Q14103,Q5BKZ1,Q9NWX6,Q9NQZ7,Q9H4M9,Q99747,Q96EK5,Q16706,O15127,O15031,O75494,O75845,Q567V2,Q86YV9,Q92520,Q9NWM8,Q9Y2Y6,Q9UHQ4,Q07666,P67870,O95721,P55795,Q96CS2,Q96EN8,Q9BZD4,Q9NNW5,Q5ZPR3,Q9Y680,Q9Y2G5,Q9UBC1,Q16527,O43237,O14641,O14654,P08754,P09471,Q6PIJ6,Q8WWQ0,Q9ULE6,P98194,Q9NTK5,O43164,O00459,O00116,P07942,Q13242,Q6P1K2,Q96RS0,Q9H0H5,Q9UBU8,Q9H0U4,Q9NXR7,Q9NRA8,P51991,Q96KA5,Q92733,Q7Z4L5,Q9UKZ1,Q8NBT2,Q9UQB8,Q10472,P51151,O00192,O00161,Q01844,Q96ES7,Q9H6E4,Q9BUP3,Q96D46,Q07955,O43252,P39687,Q02241,Q15833,Q9Y277,Q9Y673,Q6PJG6,Q8IXB1,O14964,P08670,O75663,O95881,P62995,P83916,Q13185,Q9BWF3,Q3ZCQ8,Q9Y5Z9,Q9H9P8,Q7RTS9,Q5H8A4,Q13740,Q13614,P43155,Q14344,Q12893,Q9H270,Q13308 394 +Tclin 0.4376628606808742 1.4641250966579311 0.1431597712486083 0.4609868085861159 0.2863195424972167 92 O75306,P23458,P00533,P06280,P55011,P07947,Q9Y2I1,P51970,P10253,Q14145,P0DP25,Q9BVA1,P29317,P21964,O43676,P00374,Q16739,O96000,P48735,Q7L0J3,P05556,Q9Y6M9,P49721,Q99808,P07437,P05026 26 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7c1856bcdf842316deda863782461c73bd5b3d41 --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACE2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADAT3", "ADCY3", "ADD1", "ADD2", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALG9", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKRD52", "ANKS1A", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARID4B", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL6IP6", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASNSD1", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATM", "ATP11C", "ATP13A1", "ATP13A2", "ATP13A3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATRN", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BANP", "BAP1", "BAP18", "BARD1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT1", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BEND3", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C10orf88", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C15orf40", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C21orf59", "C2CD2", "C2CD5", "C2orf49", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf33", "CAB39", "CABIN1", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CASP8AP2", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX4", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC137", "CCDC138", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCDC97", "CCNB1", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD109", "CD276", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK7", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPI", "CENPU", "CENPV", "CEP170", "CEP250", "CEP290", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLK2", "CLK3", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COCH", "COG3", "COG4", "COG7", "COG8", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPE", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CREG1", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTBS", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DMD", "DMXL1", "DMXL2", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4ENIF1", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENPP4", "ENTPD7", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM105A", "FAM114A2", "FAM120A", "FAM120B", "FAM162A", "FAM177A1", "FAM192A", "FAM208A", "FAM213A", "FAM234B", "FAM3C", "FAM49B", "FAM50A", "FAM83D", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FAT1", "FAU", "FBL", "FBXO21", "FBXO22", "FBXO38", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FN3KRP", "FNBP1", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FREM2", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALE", "GALK1", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GGT7", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GIT1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRAMD1A", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JAK1", "JCAD", "JPT2", "JUP", "KANK2", "KARS", "KAT5", "KAT7", "KATNA1", "KCTD10", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0100", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA1549", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFAP3", "KIFBP", "KIFC1", "KIN", "KIRREL1", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "L2HGDH", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDB1", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN2", "LMAN2L", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRIG1", "LRIG2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRR1", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYSMD3", "LZIC", "LZTFL1", "M6PR", "MACF1", "MACROD1", "MAD2L1BP", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4", "MAP4K4", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBLAC2", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED27", "MEN1", "MEPCE", "MESD", "METAP2", "METTL13", "METTL15", "METTL17", "METTL7B", "MFAP1", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGA", "MGAT2", "MGEA5", "MGRN1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKL2", "MKRN2", "MLEC", "MMAB", "MMADHC", "MMGT1", "MMS19", "MMS22L", "MOB4", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRC2", "MRE11", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTFR1", "MTFR1L", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA4", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NEO1", "NEPRO", "NES", "NEU1", "NF1", "NF2", "NFATC2IP", "NFKBIL1", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NID1", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME4", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "OAT", "OBSL1", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC1", "ORC2", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSTM1", "OTUB1", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PAM", "PAN2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4K2B", "PI4KA", "PI4KB", "PIAS1", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGO", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLEKHA7", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNA3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNMA1", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "PODXL", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKACB", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSER1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB31", "RAB32", "RAB33B", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1CC1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMI1", "RMND1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF149", "RNF20", "RNF213", "RNF219", "RNF31", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCAMP4", "SCAP", "SCARA3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL1", "SCYL2", "SDAD1", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SELENOI", "SENP3", "SENP6", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGSH", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIAE", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG6", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMPDL3A", "SMPDL3B", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX25", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORL1", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPHK2", "SPOUT1", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSFA2", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STK3", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYDE1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TAX1BP1", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TCTN3", "TDRD7", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX2", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "TGOLN2", "TGS1", "THADA", "THAP11", "THEM6", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TIPRL", "TJP1", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM11", "TMEM115", "TMEM126B", "TMEM14C", "TMEM160", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM206", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMEM98", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIO", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2B", "TRMT5", "TRMT6", "TRMU", "TROVE2", "TRPC4AP", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TSR3", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC38", "TTC39C", "TTC4", "TTF2", "TTI2", "TTK", "TTLL12", "TTLL4", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP1", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBIAD1", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "URGCP", "UROD", "USE1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP32", "USP33", "USP34", "USP36", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAC14", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VLDLR", "VMP1", "VPS11", "VPS13A", "VPS13C", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "VTI1B", "WAPL", "WARS", "WASF2", "WASHC3", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR70", 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9.720873786407768 1.0723891387155546 0.1672146303539832 2.245095774833478 1.0461446620678432 1.744521381224598 0.248179764200939 0.0001193358554663 0.0001017478453213 2.7844996115802127e-05 6.919512692359094e-05 1.3513383296473486e-06 +Lipid transport 8 33 2.4926490080083163 0.0126794116096551 5.140776699029126 21.796116504854368 0.7022879686929654 0.35525802853007 2.5598823127228028 3.5727100026626353 1.209238263022456 0.2984698606617377 0.0017964561645034 0.0402962873689797 0.0244837275894334 0.000923573561466 0.0038884735347153 +Sterol metabolism 10 33 2.46628310662126 0.0136523381852742 7.606796116504855 25.203883495145632 1.1785484151208083 0.2872927387372206 3.1377365577760563 3.096691699470945 1.2399567569518877 0.3064799172119154 3.838249264390716e-05 0.0230307909850112 0.0011293669878184 1.6783269894967037e-05 1.36484859404819e-05 +Autophagy 12 45 2.463964080484607 0.0137409881138708 8.390776699029127 32.08009708737864 0.0236963635391968 0.6475755054878071 3.8936358802040543 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of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8ac2aa34cec2b016fd06360232b6011808b58468 --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7f2d08818540feb1067bd105ea39668ccd4e63bc --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,53 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cell adhesion 0.744217505363845 3.738494896007284 0.0001851252506077 0.0324182341430841 0.0329522946081823 54 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P01130,Q9BQE5,Q9BXW6,P61916,Q9H2C2,Q9NV96,O15118,P98155 8 +Sterol metabolism 0.6187640843365294 2.4662831066212596 0.0136523381852742 0.9134347768402302 0.1824366842925247 33 P01130,Q15392,O75845,P61916,Q15800,P04062,Q9H2C2,Q16850,O15118,P98155 10 +Autophagy 0.5924883206752457 2.463964080484607 0.0137409881138708 0.9148086982016954 0.1824366842925247 45 Q9BXS4,Q7Z3C6,P53365,Q13501,Q9Y6I9,P13473,Q9H270,O95721,Q13137,Q6PHR2,Q8TDY2,Q9H0U4 12 +Steroid metabolism 0.6112171879392636 2.4594356385216174 0.0139155646230342 0.9174512535855268 0.1824366842925247 34 P01130,Q15392,O75845,P61916,Q15800,P04062,Q9H2C2,Q16850,O15118,P98155 10 +Cholesterol metabolism 0.6235052488790747 2.4146325046423014 0.0157510927090307 0.9407512007457536 0.1824366842925247 31 P01130,Q15392,P61916,P04062,Q16850,O15118,P98155 7 +Sodium transport 0.8262131131275988 2.2914495148522427 0.0219374285916955 0.9807131257417632 0.1824366842925247 9 Q9H2J7,Q96QD8,Q92581,P05026,Q9Y6M7 5 +Amino-acid transport 0.8147712127832383 2.2420493663268424 0.0249581819262869 0.9888791717033312 0.1824366842925247 9 P08195,Q9H2J7,Q96QD8,P30825 4 +Chemotaxis 0.9132174952408612 2.2318764491468683 0.0256231298163658 0.9901508224545036 0.1824366842925247 5 O94813 1 +Antiport 0.8064709903537263 2.2060236943254607 0.0273823407328388 0.9928599246241168 0.1874637173248198 9 Q92581,P51798,P51790 3 +Notch signaling pathway 0.8168918228971354 2.1738282412075174 0.0297180367639002 0.9953458907680012 0.1959189090360833 8 P05067,Q92542 2 +Adaptive immunity 0.6554376906829825 2.058032194094592 0.0395870430744802 0.999245731680528 0.2516604881163387 17 P04439,P01889,Q6PIJ6,Q03519,Q07021,P10321,Q13740 7 +Symport 0.6996770707892612 1.7964600918109472 0.0724213742418635 0.9999984567708972 0.3683144175729061 10 Q9H2J7,Q96QD8,P55011,Q9Y6M7 4 +Neurotransmitter transport 0.9712597367714206 1.6994777923178206 0.0892291954272896 0.999999940458483 0.410994644219161 2 Q7L0J3 1 +Hemostasis 0.969648133225894 1.6928945826374473 0.0904755346907233 0.9999999533382904 0.410994644219161 2 Q9Y6X5 1 +Blood coagulation 0.969648133225894 1.6928945826374473 0.0904755346907233 0.9999999533382904 0.410994644219161 2 Q9Y6X5 1 +Lipid degradation 0.5891940762676268 1.6830865024726616 0.0923583470155418 0.9999999677324184 0.410994644219161 17 Q92485,Q8NCC3,Q8NHP8,Q99519 4 +Sensory transduction 0.6841572384216027 1.6567921313978822 0.0975615084086178 0.9999999884032912 0.4235597194325362 9 Q9H6K4,P50897,O60266 3 +Inflammatory response 0.6200590140159079 1.6092674016194015 0.1075578838477575 0.9999999984032012 0.4352621319429603 13 Q92485,Q8IV08,O75882 3 +Immunity 0.4422203591041819 1.5911455526363767 0.1115768229127887 0.9999999992849464 0.4387171041516525 87 Q92485,P14174,P01889,Q9NUD5,Q13501,O43823,O00584,Q13740,P46379,Q8IV08,Q07021,Q96J02,Q13325,P04439,Q03519,Q9BY67,Q6PIJ6,P12956,Q9UQ84,P10321 20 +Hearing 0.7855058186005045 1.5212241351012106 0.1282036007815539 0.9999999999752324 0.4754216862315957 4 P98164 1 +Sugar transport 0.9024979854955668 1.4181973819652864 0.1561331460548216 0.9999999999999248 0.5275291344721179 2 P11166 1 +Vision 0.638527222592028 1.380007332677354 0.1675843871352194 0.9999999999999932 0.5275291344721179 8 Q9H6K4,P50897 2 +Peroxisome biogenesis 0.7110991668906058 1.218980885321599 0.2228514475249023 1.0 0.6316036507111561 4 Q9Y5Y5,O14734,P56589 3 +Glyoxylate bypass 0.8431372549019742 1.1768710869361834 0.2392469638577772 1.0 0.6316036507111561 2 P48735 1 +Biomineralization 0.8428686543110476 1.1757881206395997 0.2396795546046966 1.0 0.6316036507111561 2 Q6P4Q7 1 +Detoxification 0.825141015310243 1.1045827500925909 0.26934042900871 1.0 0.6316036507111561 2 P34913 1 +Aromatic hydrocarbons catabolism 0.825141015310243 1.1045827500925909 0.26934042900871 1.0 0.6316036507111561 2 P34913 1 +Neurogenesis 0.4105186106094692 1.091928622256466 0.2748644758761382 1.0 0.6316036507111561 58 Q9P265,Q96EK5,Q9Y6N7,Q8WUJ1,P55209,O94813,Q06787,Q8WWV3,Q15375,Q8IUH3,Q14012,Q9P2X3,O14786,P46934,Q9ULH0,P98164 16 +Innate immunity 0.3881507852998426 0.987084774837844 0.3236010809702754 1.0 0.6776587342671649 65 Q92485,P14174,P04439,P01889,P10321,Q07021,O00584 7 +Angiogenesis 0.446497946910124 0.8281570776077677 0.4075815483648437 1.0 0.7239835980721084 17 P35613,Q08431,P29317,O14786,Q9H2J4 5 +Sterol biosynthesis 0.4327544019151114 0.8118728695283952 0.4168645835271141 1.0 0.7239835980721084 20 Q15800,O75845,Q16850,Q15392 4 +Glycogen metabolism 0.4943420407103371 0.671323349074483 0.5020145633185962 1.0 0.756044175900661 7 Q93100 1 +Electron transport 0.37464789008738 0.6592012506003176 0.509766543962634 1.0 0.756044175900661 45 Q9H1E5,O43396,Q6DKK2,O43169,O43676,P51970,O96000,Q9Y6M9 8 +Cholesterol biosynthesis 0.4137296729317302 0.646141716145029 0.5181875812352845 1.0 0.756044175900661 18 Q15800,Q16850,Q15392 3 +Ubiquinone biosynthesis 0.5240652857010251 0.6348958186513445 0.5254963643323207 1.0 0.7604744134240088 5 Q9Y5Z9,Q8NI60,Q86YH6 3 +Sodium/potassium transport 0.6883396023643146 0.6233280753982876 0.533068951903064 1.0 0.7633795115703458 3 P54709,P05026 2 +Oogenesis 0.5276241156311796 0.5106318934153563 0.6096088388863383 1.0 0.7978703920718252 4 Q96RD7 1 +Respiratory chain 0.361371881666548 0.4707747925610091 0.6378015673475688 1.0 0.8202400680833944 30 O75380,P08574,Q6DKK2,P51970,O75306,O43676,O14949,O96000,Q96CU9,Q9Y6M9 10 +Glycogen biosynthesis 0.4759891524784551 0.4551135989740754 0.6490275150761253 1.0 0.8202400680833944 5 P31751 1 +Hydrogen ion transport 0.3754039482189949 0.443562361265447 0.6573590232427438 1.0 0.8202400680833944 20 Q93050,Q15904 2 +Steroid biosynthesis 0.355215166548926 0.387027587580481 0.698735784487412 1.0 0.8518833536901325 26 Q15392,O75845,P56937,Q15800,Q16850 5 +Calcium transport 0.394955390129061 0.3560877475957001 0.7217748526596357 1.0 0.8714833456755906 11 Q96RD7,Q9NWR8,P98194,Q8NE86,P20020,Q13586,P16615 7 +Carbohydrate metabolism 0.3370757997773135 0.272355596129277 0.7853486117006558 1.0 0.9257751846537532 28 P31751,Q93100,Q8NCH0,Q99519 4 +Branched-chain amino acid biosynthesis 0.5549288208433996 0.2246153461193461 0.822278525450798 1.0 0.9442940485822068 2 O15382 1 +Proline biosynthesis 0.4833422890918759 0.1279761234147539 0.8981678684026613 1.0 0.9868758060226772 3 Q96C36,P54886 2 +Asparagine biosynthesis 0.4837496642492523 0.1176057582766634 0.9063800421687476 1.0 0.9897892485032947 2 Q9NWL6 1 +Phospholipid biosynthesis 0.3196720987208574 0.1014507797312524 0.919192627974655 1.0 0.997660291338345 18 Q9HCL2 1 +Differentiation 0.3325508318811407 0.0482279874017101 0.9615345454132916 1.0 1.0 109 Q99523,Q9P273,Q9BWF3,Q13501,P46379,Q07820,Q8IWT6,Q96EK5,Q8IUH3,Q14012,P56545,Q96RD7,Q16527,Q08J23,Q9BY67,P29317,Q13685,O14786,Q9H0H5,Q04721,O94813,P51114,Q9BUP3,Q9Y6N7 24 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..cf05e5f10f4f7e8adbaae34e7d2dea6747b28b7f --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Anion exchange", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Blood coagulation", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Carnitine biosynthesis", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Copper transport", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Hemostasis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Iron storage", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Menaquinone biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "Olfaction", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sexual differentiation", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "cAMP biosynthesis", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF3", "ABHD12", "ABHD16A", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACE2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAR", "ADCY3", "ADGRE5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFF4", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT2", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEX1", "API5", "APIP", "APOL2", "APOO", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP2", "ARG2", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARID4B", "ARIH1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL8B", "ARMC10", "ARMT1", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASNSD1", "ATAD2", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATM", "ATP11C", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATRN", "ATRX", "AUP1", "AURKA", "AURKB", "BABAM1", "BABAM2", "BAG6", "BAHD1", "BAK1", "BANF1", "BANP", "BAP1", "BARD1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT1", "BCAT2", "BCCIP", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BEND3", "BET1", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOP1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1QBP", "C2CD5", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CAMK1", "CAMK2G", "CAMLG", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASP8", "CBL", "CBX2", "CBX3", "CBX4", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC86", "CCNB1", "CCNK", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC27", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDK7", "CDK9", "CDKAL1", "CDS2", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPU", "CENPV", "CEP250", "CEP290", "CEP55", "CERS1", "CERS2", "CETN2", "CFL1", "CGGBP1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHID1", "CHKA", "CHM", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CIAPIN1", "CIRBP", "CISD2", "CIT", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLIC1", "CLINT1", "CLPTM1", "CLPTM1L", "CLSTN3", "CLTA", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT9", "COASY", "COCH", "COG3", "COG7", "COG8", "COL4A3BP", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPS7B", "COPZ1", "COQ5", "COQ8A", "CORO7", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRAT", "CREG1", "CRNKL1", "CROT", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBI", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN3", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX35", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLG1", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC13", "DNAJC2", "DNAJC3", "DNASE2", "DNM1", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPY30", "DPYSL2", "DSC3", "DSG2", "DST", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHHADH", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4ENIF1", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "EMC4", "EMG1", "EML4", "ENO1", "ENO2", "ENPP1", "ENPP4", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM162A", "FAM208A", "FAM50A", "FAM83D", "FANCA", "FANCD2", "FANCI", "FAR1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FAT1", "FBL", "FBXO21", "FBXO22", "FBXO38", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FNBP1", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FREM2", "FRYL", "FTL", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALE", "GALK1", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCC2", "GCFC2", "GCLC", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGPS1", "GGT7", "GHITM", "GID8", "GINS3", "GINS4", "GLE1", "GLRX", "GM2A", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPHN", "GPI", "GPKOW", "GPR89B", "GRAMD1A", "GRB2", "GRIPAP1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HERC5", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIP1", "HIP1R", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGXB4", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK2", "HPF1", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICE1", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "ILF2", "ILF3", "ILVBL", "IMP3", "IMP4", "IMPACT", "IMPDH1", "IMPDH2", "INA", "INCENP", "INTS13", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IRF2BP1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JCAD", "JUP", "KANK2", "KARS", "KAT5", "KAT7", "KATNA1", "KCTD10", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDLR", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN2", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LRPPRC", "LRR1", "LRRC41", "LRRC8A", "LRRC8C", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MACROD1", "MAGED1", "MAGT1", "MANF", "MAP1S", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED27", "MEN1", "MESD", "MFAP1", "MFGE8", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGA", "MGEA5", "MGRN1", "MGST2", "MIA3", "MICAL3", "MICALL1", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MKL2", "MKRN2", "MLEC", "MMGT1", "MMS19", "MMS22L", "MOB4", "MOCOS", "MOCS1", "MOCS3", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MRC2", "MRE11", "MRM3", "MRPL41", "MRPL58", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCEH1", "NCKAP1", "NCOA4", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEK9", "NELFA", "NELFCD", "NELFE", "NEO1", "NES", "NEU1", "NFRKB", "NFS1", "NHP2", "NID1", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME4", "NOA1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP10", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NUBP2", "NUCKS1", "NUDC", "NUDCD1", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "ORC1", "ORC2", "ORC3", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "OTULIN", "PA2G4", "PAAF1", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PAN2", "PANK4", "PANX1", "PAPOLA", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCDH7", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDK1", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDZD8", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGS1", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PHKB", "PI4KB", "PIAS1", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGO", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIR", "PISD", "PITHD1", "PITPNB", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLIN3", "PLK1", "PLRG1", "PMF1", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPT1", "PODXL", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POP1", "PPAT", "PPCDC", "PPHLN1", "PPID", "PPIE", "PPIF", "PPIH", "PPIL2", "PPIL3", "PPOX", "PPP1CA", "PPP1R8", "PPP2R1A", "PPP5C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKCA", "PRKCD", "PRKDC", "PRKRA", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTK7", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PURB", "PUS1", "PUS7", "PWP1", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB33B", "RAB35", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RANBP3", "RANBP6", "RAPGEF2", "RARS", "RARS2", "RB1CC1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM14", "RBM15B", "RBM17", "RBM22", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCOR1", "REEP3", "REEP4", "RELA", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIPK1", "RMDN3", "RMI1", "RMND1", "RNASET2", "RNF14", "RNF149", "RNF20", "RNF213", "RNF219", "RNF31", "RNF40", "RNMT", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP30", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RPUSD3", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL24D1", "RTCB", "RTF1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A13", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCAMP4", "SCAP", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCML2", "SCP2", "SCRIB", "SCRN1", "SCYL1", "SDAD1", "SDHA", "SDHB", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SELENOI", "SENP3", "SENP6", "SEPT2", "SEPT7", "SEPT9", "SERPINH1", "SET", "SETD1A", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT1", "SHMT2", "SHPRH", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG6", "SMG8", "SMN1*", "SMNDC1", "SMPDL3B", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX25", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SON", "SORL1", "SORT1", "SPATA5", "SPC24", "SPDL1", "SPECC1L", "SPEN", "SPOUT1", "SPTLC1", "SPTLC2", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRM", "SRPK1", "SRPK2", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STK26", "STK3", "STK4", "STMN1", "STRAP", "STRBP", "STUB1", "STX12", "STX18", "STX5", "STX6", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNGR2", "TACC3", "TAF6L", "TAF9B", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TARSL2", "TAX1BP1", "TBCB", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCTN3", "TDRD7", "TDRKH", "TECR", "TEFM", "TENM3", "TERF2IP", "TEX2", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "TGS1", "THAP11", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TK1", "TLE3", "TLN1", "TM7SF2", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM115", "TMEM14C", "TMEM206", "TMEM214", "TMEM30A", "TMEM38B", "TMEM59", "TMF1", "TMLHE", "TMX1", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOLLIP", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TP53", "TP53BP1", "TPI1", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAPPC11", "TRAPPC4", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2B", "TRMT5", "TRMT6", "TRMU", "TROVE2", "TRPC4AP", "TRRAP", "TSFM", "TSG101", "TSNAX", "TSR1", "TSR2", "TSR3", "TTC19", "TTC26", "TTC4", "TTF2", "TTLL12", "TTYH3", "TUBB2B", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBL5", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URGCP", "UROD", "USE1", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP32", "USP33", "USP34", "USP36", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UXT", "VAC14", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VIRMA", "VLDLR", "VMP1", "VPS11", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VTI1B", "WAPL", "WARS", "WASF2", "WASHC3", "WASHC5", "WASL", "WBP11", "WDR12", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR48", "WDR5", "WDR6", "WDR75", "WIPI2", "WLS", "WRN", "WRNIP1", "WTAP", "WWP2", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YIPF4", "YKT6", "YLPM1", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "ZBTB10", "ZC3H11A", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCCHC9", "ZMYM2", "ZMYND8", "ZNF131", "ZNF277", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512", "ZNF638", "ZNF644", "ZNF687", "ZNF830", "ZPR1", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["AAMP", "ACOT8", "ADCY3", "ADGRE5", "AKAP8", "AKT2", "ALCAM", 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b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mucopolysaccharidosis 5 7 2.6169906851280627 0.0088708762046447 2.254854368932039 4.752427184466019 0.4843930061917075 0.2034155563537636 0.9831595235232706 0.7286567852681505 1.626107445717624 0.2463507210616131 1.5365616255530653e-07 1.64649785891995e-07 3.2670379567832186e-08 7.751339245084413e-08 4.709357290896995e-06 +Gangliosidosis 4 5 2.519705005126366 0.0117453222756844 2.8567961165048543 4.902912621359223 0.2158556094961241 0.1574800557957235 1.2213224676890235 0.2960767122713962 1.9039254823866087 0.2239345049259472 1.402816173698501e-08 2.309616566364919e-12 7.402823185757473e-11 7.85578396891505e-09 2.618746245991888e-07 +Neuronal ceroid lipofuscinosis 6 7 2.4174037407768534 0.0156316678751649 2.1941747572815533 3.616504854368932 0.8145003765175237 0.1716854616439567 0.950812145720796 0.8293870806734848 1.6764073513361384 0.2241811956153294 9.49987567798378e-06 2.3666612945957126e-05 0.0001778916397324 5.41373461507268e-06 3.850375245202498e-07 +Spinocerebellar ataxia 1 10 2.248360490332442 0.0245532123924923 2.29126213592233 9.594660194174756 0.4684523610351578 0.5099609720531028 1.6362464027486996 1.23589935457103 0.8565769186147023 0.2999468232045417 0.146042597995461 0.0065792573185243 0.0237627189197599 0.1211421538065826 0.3433653057642475 +Amyloidosis 2 5 2.069283256052308 0.0385195139462075 1.087378640776699 3.703883495145631 0.4647215876526214 0.3864606223560753 0.9068969404042873 1.1014925734380785 1.1974619704686245 0.3115672738393393 0.0070123051135818 0.0023758658868836 0.0003602808960722 0.0050923434600555 0.033288888151673 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..79ce1b3eaf07ea53a1ee6ff6ecd63cc160c73450 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 117, + "title": "Average number of proteins per term", + "value": 25.564102564102566 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2b200eab41c7781655a3536c035f1bdb2cc3b278 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3d34b568b30e7d60d3a46eb7ed476627246fe280 --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,45 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mucopolysaccharidosis 0.9439729429343604 2.6169906851280627 0.0088708762046447 0.6474361121931363 0.343550676563771 7 P16278,P34059,P54802,P08236,P15586 5 +Gangliosidosis 0.987903225806452 2.519705005126366 0.0117453222756844 0.7490086208936748 0.343550676563771 5 P06865,P17900,P16278,P07602 4 +Neuronal ceroid lipofuscinosis 0.8940290478752152 2.4174037407768534 0.0156316678751649 0.8417137684068025 0.3657810282788586 7 O14773,P50897,Q8NHS3,Q9NQ11,Q9UBX1,O75503 6 +Spinocerebellar ataxia 0.798543646762063 2.248360490332442 0.0245532123924923 0.9454469306613296 0.4301523875140373 10 O14773 1 +Amyloidosis 0.8720697912263156 2.0692832560523073 0.0385195139462075 0.9899066461722182 0.4506783131706284 5 P05067,Q9Y287 2 +Microphthalmia 0.7585875453867235 1.8506572128565089 0.0642188832356234 0.99957597599853 0.5366863813262813 7 P53701 1 +Dystroglycanopathy 0.8059694859942594 1.802367555112243 0.0714875963150598 0.9998297206295342 0.5540176423107515 5 Q14118,O43505 2 +Alzheimer disease 0.7994827860811471 1.7758169295576267 0.0757630963843762 0.9999007691464116 0.5540176423107515 5 P05067 1 +Lissencephaly 0.6663468136189941 1.7085424155580018 0.087535743123023 0.9999778560156684 0.5947180657307116 11 Q14118,O43505,Q9H9S5 3 +Niemann-Pick disease 0.9669621273166832 1.6819202869553584 0.092584298227361 0.9999884299316432 0.5947180657307116 2 P61916 1 +Gaucher disease 0.9613215149073372 1.6588657040308497 0.0971428568763697 0.99999358158946 0.5947180657307116 2 P07602 1 +Metachromatic leukodystrophy 0.9556809024979906 1.6358009226608037 0.1018812588726323 0.9999965322338994 0.5947180657307116 2 P07602 1 +Osteopetrosis 0.9500402900886428 1.6127277104972746 0.1068036774892537 0.9999981769844256 0.5947180657307116 2 Q86WC4 1 +Amyotrophic lateral sclerosis 0.5878033844535164 1.5678746497671134 0.116910388989798 0.999999518541626 0.5947180657307116 15 Q13501,Q9NUM4 2 +Glycogen storage disease 0.6026566223140384 1.460884791582896 0.1440470609642381 0.9999999875078602 0.615765777934217 12 P13473,Q93100,P10253 3 +Congenital muscular dystrophy 0.6655752247360186 1.4410178561058964 0.1495796382785248 0.9999999941502534 0.615765777934217 7 Q14118,O43505 2 +Ehlers-Danlos syndrome 0.7565170653050113 1.4036271292125286 0.1604299122032721 0.9999999986978412 0.615765777934217 4 Q96L58,Q8NCH0,Q9NWM8 3 +Hirschsprung disease 0.8874563524039868 1.356769789373174 0.1748543695046198 0.9999999998285724 0.615765777934217 2 P42892 1 +Leukodystrophy 0.5169309823541705 1.3538031800162975 0.1757991788680939 0.9999999998500778 0.615765777934217 20 P07602,Q9NUM4 2 +Ichthyosis 0.5959846137180057 1.298325348704292 0.1941755594001666 0.9999999999892816 0.6365363080717842 10 P04062,P15289 2 +Limb-girdle muscular dystrophy 0.5662839667002418 1.2096408744626597 0.2264167265923946 0.9999999999999096 0.6792501797771839 11 O14979,Q9H9S5,Q14118 3 +Rhizomelic chondrodysplasia punctata 0.8321246306741833 1.1325663192786983 0.2573964193220743 0.9999999999999992 0.734521489284944 2 O00116 1 +Epilepsy 0.3789589765325067 1.1098251383499669 0.2670743845375989 1.0 0.7439929283547398 74 O14773,P09471,P27544,O75787,Q13510,Q9H2C2,P67870,Q6PJG6,P11166,Q92581,Q14108,O75503 12 +Parkinsonism 0.5040199129188382 1.0371153924719754 0.2996820824397788 1.0 0.7622348618576983 14 P04062,Q15043,Q9NQ11 3 +Cushing syndrome 0.7915783232370617 0.9863527964288628 0.3239600200513195 1.0 0.7896525488750914 3 P10644 1 +Neurodegeneration 0.4814296602337683 0.8982752212300071 0.3690388393968939 1.0 0.8393250794100775 167 O14773,Q13501,P27544,Q9Y287,Q9NWW5,P04062,P05067,Q9UBX1,O75503,Q9ULH0,Q8IV08,P50897,P54802,P06865,Q13510,P07686,Q92673,O15269,Q14108,Q9NQ11,P02792,Q9NUM4,O75787,Q04656,Q15043,P35637,O95831,Q8NHS3 28 +Premature ovarian failure 0.7382224788041327 0.7937894751227285 0.4273180008280974 1.0 0.9090219290343164 3 Q06787 1 +Joubert syndrome 0.524530561815294 0.7002426793054966 0.4837757621842817 1.0 0.9355631885539808 6 Q7Z4L5 1 +Meckel syndrome 0.7093956421236158 0.6938564125361489 0.4877722606990839 1.0 0.9355631885539808 3 Q7Z4L5 1 +Diabetes mellitus 0.4443845169718756 0.5919059889520826 0.5539135431797573 1.0 0.9530571257651704 11 Q13217,Q5VV42,P22413,O76024,P31751,Q8TDJ6,P13807 7 +Obesity 0.4205164912774525 0.5388882164239189 0.5899639884579178 1.0 0.9589310152375032 13 Q9ULH0,O60266,Q7Z4L5,Q13049 4 +Palmoplantar keratoderma 0.4514538622054966 0.5211880228552653 0.6022357968639751 1.0 0.9652272360696588 8 Q06136,P53634 2 +FDA approved drug targets 0.4054472369580933 0.4781854503626387 0.6325182172274766 1.0 1.0 136 P15260,Q96QD8,P23786,P23458,P00533,P55011,P05067,P07947,P35610,Q9Y2I1,P06756,P33527,P10253,Q14145,Q16850,P02792,O75874,P29317,P21964,P98194,P00374,Q13423,P02786,Q7LG56,Q16739,P48735,Q7L0J3,P05556,P49721,P17252,Q8N0U8,P20645,Q9UNN8 33 +Dystonia 0.4621815060535852 0.451944269058654 0.6513091317297632 1.0 1.0 6 Q15043 1 +Cone-rod dystrophy 0.6062743498661577 0.3762366222603813 0.7067409915276144 1.0 1.0 3 Q6P4Q7 1 +Cataract 0.3389572894649403 0.3409050936903085 0.7331750300669921 1.0 1.0 33 P02792,P29317,Q15800,O15228,O00116,P11166,Q9H6K4,P08670 8 +Craniosynostosis 0.5699704539349975 0.2555917539552632 0.7982660863515125 1.0 1.0 2 P16435 1 +Proto-oncogene 0.3246363247880753 0.2221678333753151 0.8241832336325206 1.0 1.0 52 P35637,O14965,Q92804,P17252,Q92733,Q01105,P31751,Q01844,P00533,Q06136,Q13772,P07947 12 +Osteogenesis imperfecta 0.3578243200096883 0.1708949347977186 0.8643063795210133 1.0 1.0 9 Q32P28 1 +Senior-Loken syndrome 0.4982540961590016 0.134252984769617 0.8932025293084065 1.0 1.0 2 Q15051 1 +Alport syndrome 0.4574268063389629 0.0934723146551234 0.92552834308745 1.0 1.0 2 O60488 1 +Oncogene 0.346620161656334 0.0763614023356017 0.9391315763852064 1.0 1.0 4 Q92520 1 +Nemaline myopathy 0.3459575611066395 0.0524313319046039 0.958185009193686 1.0 1.0 2 P06753 1 +Aicardi-Goutieres syndrome 0.3085192152647081 0.0411046974776399 0.9672124297247796 1.0 1.0 4 Q5TBB1,Q9Y3Z3,P55265 3 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5d2b7aca6a74f207d74817097a426ae55ce21d20 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital dyserythropoietic anemia", "Congenital erythrocytosis", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Corneal dystrophy", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary multiple exostoses", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Peters anomaly", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Senior-Loken syndrome", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AARS", "AARS2", "ABCB1", "ABCB7", "ABCC1", "ABCD4", "ABHD12", "ABI1", "ACAA1", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAR", "ADCY3", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFF4", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKAP13", "AKAP9", "AKR1B1", "AKT2", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG9", "AMPD2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANO10", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA7", "AP1B1", "AP1S2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APEX1", "APOL2", "APP", "APRT", "ARAF", "ARCN1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARSA", "ARV1", "ASAH1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATL3", "ATM", "ATP11C", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP7A", "ATRX", "ATXN10", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GAT1", "BANF1", "BANP", "BAP1", "BARD1", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCKDHB", "BCKDK", "BCL10", "BCLAF1", "BCOR", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD3", "BRD4", "BRIP1", "BUB1B", "BUD23", "C12orf57", "C19orf70", "C1QBP", "C21orf59", "C3orf58", "CAD", "CADM1", "CALM3", "CALR", "CAMK2G", "CAMLG", "CANT1", "CANX", "CAPN1", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBL", "CBX2", "CC2D1A", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC6", "CCNB1", "CCNK", "CCT5", "CD320", "CDC16", "CDC20", "CDC27", "CDC37", "CDC42", "CDC45", "CDC6", "CDC73", "CDH2", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDK7", "CDKAL1", "CDX2", "CENPF", "CEP250", "CEP290", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHM", "CHMP2B", "CHST14", "CISD2", "CIT", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "COA3", "COA7", "COASY", "COCH", "COG7", "COG8", "COL4A3BP", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COX15", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRAT", "CRK", "CRTAP", "CSDE1", "CSE1L", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DARS", "DARS2", "DAXX", "DBI", "DBN1", "DBT", "DCPS", "DCTN1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIS3", "DKC1", "DLD", "DLST", "DMD", "DMXL2", "DNA2", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DOCK7", "DPF2", "DPH1", "DPM1", "DSC3", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "ECT2", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EHHADH", "EHMT1", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELL", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "ENO2", "ENPP1", "EPB41", "EPB41L3", "EPHA2", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERLIN1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC6B", "EXOC8", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "FADS2", "FAF1", "FAH", "FAM120A", "FAM3C", "FAM50A", "FAM83D", "FANCA", "FANCD2", "FANCI", "FAR1", "FARS2", "FARSB", "FASN", "FASTKD2", "FAT1", "FBXO38", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP5", "FKBP8", "FKRP", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FOXC1", "FOXRED1", "FREM2", "FSCN1", "FTL", "FTO", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GALE", "GALK1", "GALNS", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GCLC", "GCLM", "GDAP1", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GGPS1", "GIGYF2", "GLA", "GLB1", "GLDC", "GLE1", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI3", "GNAO1", "GNE", "GNPAT", "GNS", "GOLGA5", "GOPC", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPHN", "GPI", "GPT2", "GRB2", "GSK3A", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2H1", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "GYS1", "H4C1*", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIKESHI", "HIP1", "HIP1R", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMGXB4", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2R", "IGHMBP2", "ILF3", "ILK", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "INTS1", "INTS8", "IPO7", "IQCB1", "IRF2BPL", "IRS4", "ISCA2", "ITGA2", "ITGAV", "ITGB1", "ITM2B", "ITPA", "IVD", "JAGN1", "JAK1", "JUP", "KANK2", "KARS", "KDM1A", "KDM3B", "KDM5A", "KDM5B", "KDSR", "KEAP1", "KIAA1549", "KIDINS220", "KIF11", "KIF14", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KLC2", "KMT2A", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LGALS3BP", "LGMN", "LIPA", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRP1", "LRP2", "LRPPRC", "LSS", "LTA4H", "LZTFL1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN2B1", "MAP1A", "MAP1B", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MARS", "MARS2", "MATR3", "MBD1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM3AP", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", 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"NOTCH2", "NPC1", "NPC2", "NPM1", "NR2F1", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "OAT", "OBSL1", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "ORC1", "OSBPL2", "OSTM1", "OTULIN", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PANX1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PDAP1", "PDCD4", "PDHA1", "PDHB", "PDK1", "PDK3", "PDP1", "PDSS1", "PDSS2", "PDXK", "PEPD", "PEX14", "PEX16", "PEX19", "PEX3", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4KA", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGO", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PINX1", "PISD", "PKM", "PKP2", "PLAA", "PLCG1", "PLCG2", "PLD3", "PLEC", "PLIN3", 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100644 index 0000000000000000000000000000000000000000..aae70391a4cf79482a3fefa5aff98f5b61b863c0 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,13 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Receptor 41 61 4.592468079680989 4.380345259180629e-06 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 4.290075589109535e-15 0.0337004996412966 4.544858308713385e-06 4.1088851009288544e-14 4.781723657501728e-14 +Glycosidase 14 23 3.576046172659487 0.0003488300672707 7.798543689320389 18.135922330097088 0.5112745472223946 0.1951515073440806 2.9064203812520417 1.9684331341643595 1.9501681029822375 0.2619382904734375 1.6150240563720764e-13 2.3697452211660948e-11 7.586688120813521e-17 2.964589886898916e-14 3.148601946993704e-13 +Host cell receptor for virus entry 16 23 3.3822849265417334 0.0007188554268364 4.509708737864078 15.157766990291265 0.7214109752050332 0.2527966464979699 2.499010078306418 1.9009100692398744 1.5211756979359785 0.2791170769282048 6.540905337298381e-10 1.0 0.0006788789579845 5.32603095196751e-07 2.816769425526894e-12 +Protease 15 95 2.5376340483121065 0.0111604618051035 20.788834951456312 82.44417475728156 1.1215350835872162 0.3507517256058336 6.07090559629836 8.079357013764625 1.4678877461728397 0.3691345771929886 0.0005122062328978 1.4076449696608436e-05 1.209031069003438e-05 0.0001399666010501 0.0081240333715322 +Carboxypeptidase 5 8 2.448660362991758 0.0143388584798982 3.1359223300970873 6.150485436893204 0.9957728306848488 0.1212034427500092 1.2071674596015187 0.4479454254223922 1.8250051834990677 0.2074401112551974 1.5188323375578437e-06 0.0023758658868836 1.0100053103379697e-05 7.740896807249238e-07 4.318273591764818e-05 +Heparin-binding 3 8 2.4079803563583626 0.0160410441038587 2.3567961165048543 6.854368932038835 0.2151021415291715 0.4976817002921777 1.5599282492786453 1.096399818915653 1.0317858467489989 0.3203044603738155 0.0049092326538637 0.1201219647894398 0.2223047329091382 0.0032545859437725 0.0349002560689848 +Transducer 8 11 2.3997938935893037 0.0164043054451792 3.466019417475728 8.91747572815534 -0.1646169358897246 0.5259738353010212 2.4077767773055085 2.0164338021708255 0.961579508666748 0.3124316516206892 0.5371396969246958 1.0 0.4724360815693985 0.4755559518983523 0.0397726884021936 +Thiol protease 4 38 2.3223393343252225 0.0202146711437241 8.558252427184467 28.449029126213592 -0.1137835481841181 0.5293090131610529 4.4562604434844255 6.130444798408687 1.0274569489992988 0.314247550671834 0.1385686663430049 0.0014729216301342 0.0161157889533151 0.0970705055296173 0.364710616880698 +Serine protease inhibitor 2 6 2.1996582054702665 0.0278311541897546 1.266990291262136 3.5266990291262137 0.2947116096628981 0.478012142815398 1.0341628901681232 1.1133635632531 1.1321039780621556 0.3315824922638006 0.0057231345736884 0.066549445548378 0.0077184558590264 0.0041470760753771 0.0276005264132961 +Protease inhibitor 2 9 2.074809977045572 0.0380041495488685 2.679611650485437 6.827669902912621 -0.1389909380340853 0.4401686430319619 1.73744367643855 1.203518872907143 1.1014803254493444 0.2988298098237953 0.0290684739516603 0.1157751708195439 0.0237627189197599 0.0215683584236732 0.1183493106079827 +Tyrosine-protein kinase 4 13 2.07347824602629 0.0381277936005712 3.7645631067961167 8.359223300970873 -0.4296571648855464 0.5474302621110606 2.167815452996528 2.2975477384226104 0.7344432012557188 0.286911595039953 0.1076023680550785 1.0 1.0 0.4834399233654581 0.2237181664771145 +Chloride channel 2 5 1.9999280716456815 0.045508031417782 1.3179611650485437 4.242718446601942 0.3211542961566963 0.4464803596968064 1.046662619600292 0.984994400629452 1.0542652350954735 0.295172924223425 0.0284648775398106 0.0479914252810258 0.0039135152062846 0.0229613270793894 0.0105083517934163 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..3cd55949aaa713010ddf6acf51ecbeae54402ba5 --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 98, + "title": "Average number of proteins per term", + "value": 44.95918367346939 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f564f887ffb1aa53f4036d59a9449d4f7fd0fe3f --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7311752d6dc044aa1f7a11f525668bbe2311dd08 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,33 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Receptor 0.8353362597630166 4.592468079680989 4.380345259180629e-06 0.0004291826503526 0.0004292738353997 61 Q99523,Q9NS69,P15260,Q5KU26,Q14118,P00533,Q8WTV0,P51805,Q9Y624,Q9Y2I1,P48960,P17301,P35613,P06756,P98155,P55899,Q92673,P24390,P11717,Q14108,P98164,Q9UBG0,P01130,P13591,P29317,O75787,P10586,P02786,Q92692,O14786,P11279,Q04721,P20645,Q15375,Q9UNN8,P30825,P78310,O75882,Q07954,O15118,Q9Y6N7 41 +Glycosidase 0.8739379923275001 3.576046172659487 0.0003488300672707 0.0336133928739569 0.0170926732962648 23 Q92485,O00754,P16278,P54802,P06865,O00462,Q9BTY2,P10253,P07686,P04066,P06280,P08236,Q01459,Q99519 14 +Host cell receptor for virus entry 0.8368285897283915 3.3822849265417334 0.0007188554268364 0.0680472517406514 0.0234826106099914 23 P17301,P35613,P06756,P01130,P13591,P29317,P02786,Q14118,P00533,P78310,P11279,Q8WTV0,Q14108,O15118,Q9Y624,Q92692 16 +Protease 0.5483359353379746 2.5376340483121065 0.0111604618051035 0.6670870684081147 0.1004763708517228 95 Q99538,O14773,Q9UIQ6,P07711,P42892,P42785,P07858,P53634,Q9HB40,Q9H3G5,O75844,O75976,P10619,Q9UBX1,P16870 15 +Carboxypeptidase 0.8824184511953255 2.448660362991758 0.0143388584798982 0.7571666865588782 0.1004763708517228 8 P42785,Q9HB40,Q9H3G5,O75976,P10619 5 +Heparin-binding 0.8725781204161481 2.4079803563583626 0.0160410441038587 0.7950044977184343 0.1004763708517228 8 P10586,O94813,P05067 3 +Transducer 0.8139254496343603 2.3997938935893033 0.0164043054451792 0.8022899857624558 0.1004763708517228 11 O14654,P08754,P09471,P02786,Q14344,P04899,P63096,P48960 8 +Thiol protease 0.5826997063622461 2.3223393343252225 0.0202146711437241 0.8648452394982791 0.1089166908412583 38 Q99538,P07711,P53634,P07858 4 +Serine protease inhibitor 0.8791604999473769 2.1996582054702665 0.0278311541897546 0.9370947990549516 0.1311317359437551 6 P05067,Q06481 2 +Protease inhibitor 0.7765455580117355 2.074809977045572 0.0380041495488685 0.977562551209132 0.1494609509142394 9 P05067,Q06481 2 +Tyrosine-protein kinase 0.7112563048642464 2.07347824602629 0.0381277936005712 0.9778434145393552 0.1494609509142394 13 P23458,Q15375,P29317,P00533 4 +Chloride channel 0.8547294933352114 1.9999280716456815 0.045508031417782 0.98958442411123 0.1592781099622371 5 Q9C0H2,Q9H813 2 +Serine protease 0.6924254639548199 1.8348263117255943 0.0665314287224856 0.9988257227772804 0.210586737927624 11 O14773,Q16740,Q2T9J0 3 +Metalloprotease 0.5526509970854975 1.8342683343193196 0.0666141722015953 0.9988358797668108 0.210586737927624 28 P42892,Q9UIQ6,O75844,O75976,P16870 5 +Porin 0.8590988006541573 1.816815865669004 0.0692453126408971 0.9991172194826364 0.2120637699627476 4 P21796 1 +Translocase 0.5405188953464689 1.7507858889020629 0.0799827981758649 0.99971685893594 0.2305386535657284 28 P08574,Q03519,Q9H7F0,P33527,O75306,Q04656,Q13423,P98194,Q9HD20,Q9NQ11,P16615 11 +Glycosyltransferase 0.469469542534523 1.4661189419262188 0.142615886198038 0.9999997173868472 0.3542817820346059 42 Q2TAA5,Q86SF2,Q10471,Q04446,O43505,Q10472,O60512,P04062,Q16739,Q68CQ7,Q9Y673,Q10469,Q9Y2G5 13 +Monooxygenase 0.7136617387750595 1.4195978138109886 0.1557248022564019 0.999999937564002 0.3542817820346059 5 Q16850,P19021 2 +Integrin 0.9065018807092956 1.4176455478012568 0.1562942751043121 0.9999999415590044 0.3542817820346059 3 P17301,P06756 2 +Endonuclease 0.5033812325706049 1.4072405284289198 0.159356077587905 0.9999999590754798 0.3542817820346059 24 O00115,O00584 2 +Nuclease 0.4294743871270648 1.1303359735949592 0.2583346817883063 0.9999999999998092 0.5134698564170139 42 O00115,Q8IV08,O00584 3 +Ion channel 0.501875128943112 0.9766242673610216 0.3287552005148861 1.0 0.5477952237705274 13 Q96RD7,Q9C0H2,Q9H813 3 +Developmental protein 0.408132491484189 0.974526709988036 0.3297950836985828 1.0 0.5477952237705274 103 Q99523,O00115,P00533,Q07820,Q96EK5,O15031,Q5SZK8,Q92520,Q8N9N5,Q16527,O14641,Q9BY67,Q13685,Q9Y4F1,O14786,Q9H0H5,Q04721,Q8NB78,Q96C57,P31751,O94813,P51114,Q15375,Q07954,Q9Y6N7 25 +Threonine protease 0.7781764059695659 0.937252878371066 0.3486284955244754 1.0 0.5498786653839799 3 Q99436 1 +Acyltransferase 0.3976073785513732 0.8554164538871478 0.3923206378448425 1.0 0.5654032721881553 41 Q86UY6,Q9UJ14,Q8IUH4,P23786,Q8NCC3,Q9HCL2 6 +Phospholipase A2 inhibitor 0.7354284179425177 0.7575051897588547 0.4487472578533982 1.0 0.6282461609947575 2 P04083 1 +Calcium channel 0.7184309511015534 0.7247938590847953 0.4685785036795953 1.0 0.6377874077861158 3 Q96RD7,Q8NE86 2 +Lyase 0.3691968408103075 0.6216161698781792 0.5341942859139692 1.0 0.6780722672278219 49 O00584,P22830,Q8NBZ7,O60266,P19021,P53701 6 +Guanine-nucleotide releasing factor 0.37676787396525 0.471621101035713 0.6371972624958104 1.0 0.7358225797893011 21 Q14185,P80303,Q02818,Q9Y4F1,A4D1U4 5 +Exonuclease 0.3502530157841448 0.3032123820332546 0.7617280134298228 1.0 0.848288014955939 21 Q8IV08 1 +Dioxygenase 0.322158534070765 0.1602383440914152 0.8726933254052898 1.0 0.95089938240091 23 Q9UPP1,O15460,Q32P28 3 +Protein phosphatase 0.2988987290636675 0.0013522369273422 0.9989210713619376 1.0 1.0 17 Q9NYA4 1 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..bf80ab34aa7086709a872d14332b26798431fadd --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "G-protein coupled receptor", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgG-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AAK1", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCC1", "ABCC4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACE2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADCY3", "ADD1", "ADD2", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALG9", "ALKBH5", "AMPD2", "ANKHD1", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "ANXA3", "APBB1", "APEH", "APEX1", "APIP", "APLP2", "APP", "APRT", "AQR", "ARAF", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARID4B", "ARIH1", "ARL8B", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATG3", "ATG4B", "ATIC", "ATL2", "ATL3", "ATM", "ATP11C", "ATP13A1", "ATP13A2", "ATP13A3", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7A", "ATRN", "ATRX", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG4", "BAG5", "BAG6", "BAHD1", "BANF1", "BANP", "BAP1", "BAP18", "BARD1", "BAZ1B", "BAZ2A", "BCAT1", "BCAT2", "BCKDHB", "BCKDK", "BCLAF1", "BCOR", "BCR", "BCS1L", "BEND3", "BIRC6", "BLM", "BLMH", "BLVRA", "BPHL", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIP1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "C10orf88", "C12orf43", "CABIN1", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CAMK1", "CAMK2G", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBL", "CBR1", "CBX2", "CBX3", "CBX4", "CC2D1A", "CCAR1", "CCAR2", "CCDC47", "CCNB1", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD320", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDCA7L", "CDIPT", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDK7", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPU", "CEP290", "CEP55", "CERS1", "CERS2", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHKA", "CHM", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIRBP", "CIT", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLK2", "CLK3", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT9", "CNP", "COASY", "COLEC12", "COLGALT1", "COMT", "COPA", "COPS5", "COQ5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "CPD", "CPE", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CROT", "CRYZ", "CS", "CSDE1", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTBS", "CTDSPL2", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CUL5", "CXADR", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DMD", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EGFR", "EGLN1", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENPP4", "ENTPD7", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERI1", "ERMP1", "ERO1A", "ERO1B", "ERP44", "ESD", "ESPL1", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "F11R", "FADS2", "FAH", "FAHD1", "FAM120A", "FAM120B", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLYWCH1", "FMR1", "FN3KRP", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FREM2", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALE", "GALK1", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GGT7", "GIT1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GUSB", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IFNGR1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INF2", "INPP4A", "INTS11", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "IRS4", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITPA", "ITPK1", "IVD", "JAK1", "KARS", "KAT5", "KAT7", "KATNA1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIAA1147", "KIF11", "KIF14", "KIF15", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KRR1", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDB1", "LDHA", "LDHB", "LDLR", "LEMD3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC8A", "LRRC8C", "LRWD1", "LSG1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MACROD1", "MAGED1", "MAGED2", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MANEA", "MANF", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MAT2A", "MATR3", "MBD1", "MBD3", "MBLAC2", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED27", "MEN1", "MEPCE", "MESD", "METAP2", "METTL13", "METTL15", "METTL17", "METTL7B", "MFN1", "MFN2", "MGA", "MGAT2", "MGEA5", "MGRN1", "MGST2", "MGST3", "MICAL3", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKL2", "MKRN2", "MMAB", "MMS19", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPRIP", "MPST", "MRC2", "MRE11", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTR", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCAM1", "NCBP3", "NCEH1", "NCL", "NCOA4", "NCOA5", "NCOR1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEK9", "NELFA", "NELFCD", "NELFE", "NEPRO", "NES", "NEU1", "NF1", "NFRKB", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NME3", "NME4", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR2F1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NUSAP1", "NXF1", "OAT", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC1", "ORC3", "OTUB1", "OTULIN", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PALLD", "PAM", "PAN2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD4", "PDCL3", "PDE12", "PDE8A", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM7", "PDP1", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB2", "PHC2", "PHF2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PHKB", "PI4K2A", "PI4K2B", "PI4KA", "PI4KB", "PIAS1", "PIGG", "PIGK", "PIGO", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNA3", "PLXNB2", "PMF1", "PMPCB", "PMS1", "PMVK", "PNKP", "PNMA1", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R8", "PPP5C", "PPT1", "PPT2", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKACB", "PRKCA", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS1", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "RAB10", "RAB18", "RAB1A", "RAB1B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RAD51AP1", "RAD54B", "RAD54L2", "RALA", "RALGAPB", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RELA", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC3", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOK2", "RIOX1", "RIPK1", "RNASEH2A", "RNASET2", "RNF14", "RNF149", "RNF20", "RNF213", "RNF219", "RNF31", "RNF40", "RNMT", "RNPEP", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1B", "RRP7A", "RRP8", "RRP9", "RSBN1L", "RSF1", "RTCA", "RTCB", "RTF1", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL1", "SDHA", "SDHB", "SEC11A", "SEC61A1", "SEC63", "SELENBP1", "SELENOI", "SENP3", "SENP6", "SEPHS1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGPL1", "SGSH", "SGTA", 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0.256881456821794 5.463351773637434 6.9884942404294375 1.5049506819867255 0.3173597508227758 6.769717867000185e-12 5.27172786316786e-08 2.5384351480382044e-07 2.8614968075515987e-10 7.505616387921447e-09 +CD markers 21 30 3.654389044652184 0.0002577951171205 6.548543689320389 16.62378640776699 0.159361413045758 0.3347758559744795 3.625700175504636 4.1209525283344535 1.5119526885132668 0.3016304730463651 2.5575243545214257e-08 0.0966324665930835 7.270369264469176e-05 3.7263157331392695e-08 1.113236817919753e-09 +Human disease related genes 162 1089 2.6857771758536617 0.0072361328299523 172.1504854368932 917.6092233009708 0.226735531611559 0.5906050594985414 44.37633274090302 87.90976293782784 1.0325467686959249 0.3753934615149693 6.795991836739589e-05 9.07205814659391e-06 1.1007074961607185e-05 2.230167963224607e-05 7.263775046007495e-06 +Candidate cardiovascular disease genes 4 13 2.445707423225038 0.0144568263665916 2.563106796116505 9.29368932038835 0.1164468151756199 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a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f74aa1f193d204d4398ae11fbcd65bea64af3bd4 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a71cfa0a6a37bc0cadf3cf4adefe76e10f775619 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,11 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted secreted proteins 0.7301322812427518 4.391198567295455 1.1272753325686224e-05 0.0002479712210535 0.0002480005731651 76 Q92485,O75629,P14174,Q8NDZ4,P07858,Q9UM22,Q9HB40,P80303,O00584,Q9Y287,Q9BTY2,P00533,Q9P2K2,O60888,Q08380,P05067,P19021,P48960,O75718,O43405,Q92484,P61916,Q07021,Q92673,P14543,P02786,O14786,Q8WUJ1,Q08431,O94813,P78310,O75882,Q9H9S5 33 +CD markers 0.8334894718426105 3.654389044652184 0.0002577951171205 0.0056561670561484 0.0028357462883259 30 P15260,P13473,Q9Y624,P48960,P17301,P35613,P06756,P11717,Q9UBG0,Q9NPF0,P13591,Q08722,P02786,O14786,P11279,P05556,Q9UNN8,P08195,Q6YHK3,Q07954,Q92692 21 +Human disease related genes 0.3434633789223994 2.6857771758536617 0.0072361328299523 0.147663343784874 0.0530649740863175 1089 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162 +Candidate cardiovascular disease genes 0.7881484772579543 2.445707423225038 0.0144568263665916 0.2741207343284979 0.0546187092193285 13 P06865,Q07954,Q9UNN8,P07858 4 +Disease related genes 0.334581643873276 2.4348974279783566 0.0148960116052714 0.2812039152239295 0.0546187092193285 1203 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a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..dbba5a1c277745f2a26be90f0c0765e17a65df6d --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "G-protein coupled receptors", "Human disease related genes", "Metabolic proteins", "Nuclear receptors", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACE2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADCY3", "ADD1", "ADD2", "ADD3", "ADGRE5", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALG9", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKRD52", "ANKS1A", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARID4B", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL6IP6", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASNSD1", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATM", "ATP11C", "ATP13A1", "ATP13A2", "ATP13A3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATRN", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BANP", "BAP1", "BAP18", "BARD1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT1", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCL10", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BEND3", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C10orf88", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C15orf40", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C21orf59", "C2CD2", "C2CD5", "C2orf49", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf33", "CAB39", "CABIN1", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX4", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC137", "CCDC138", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCDC97", "CCNB1", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD109", "CD276", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK7", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPI", "CENPU", "CENPV", "CEP170", "CEP250", "CEP290", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHKA", "CHM", "CHMP2B", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLK2", "CLK3", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COCH", "COG3", "COG7", "COG8", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPE", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CREG1", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTBS", "CTDSPL2", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBI", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAKD", "DCD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DMD", "DMXL1", "DMXL2", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EGLN1", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4ENIF1", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENPP1", "ENPP4", "ENTPD7", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM105A", "FAM114A2", "FAM120A", "FAM120B", "FAM162A", "FAM177A1", "FAM192A", "FAM208A", "FAM213A", "FAM234B", "FAM3C", "FAM49B", "FAM50A", "FAM83D", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FAT1", "FBL", "FBXO21", "FBXO22", "FBXO38", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FN3KRP", "FNBP1", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FREM2", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALE", "GALK1", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GGT7", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GIT1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRAMD1A", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HERC5", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JAK1", "JCAD", "JPT2", "JUP", "KANK2", "KARS", "KAT5", "KAT7", "KATNA1", "KCTD10", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0100", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA1549", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFAP3", "KIFBP", "KIFC1", "KIN", "KIRREL1", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDB1", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN2", "LMAN2L", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRIG1", "LRIG2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRR1", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYSMD3", "LZIC", "LZTFL1", "M6PR", "MACF1", "MACROD1", "MAD2L1BP", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4", "MAP4K4", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBLAC2", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED25", "MED27", "MEN1", "MEPCE", "MESD", "METAP2", "METTL13", "METTL15", "METTL17", "METTL7B", "MFAP1", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGA", "MGAT2", "MGEA5", "MGRN1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKL2", "MKRN2", "MLEC", "MMAB", "MMADHC", "MMGT1", "MMS19", "MMS22L", "MOB4", "MOCOS", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRC2", "MRE11", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTFR1", "MTFR1L", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR14", "MTMR2", "MTMR4", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA4", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NENF", "NEO1", "NEPRO", "NES", "NEU1", "NF1", "NF2", "NFATC2IP", "NFKBIL1", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NID1", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME4", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NUTF2", "NVL", "NXF1", "OAT", "OBSL1", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC1", "ORC2", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSTM1", "OTUB1", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PAM", "PAN2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4K2B", "PI4KA", "PI4KB", "PIAS1", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGO", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLEKHA7", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNA3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNMA1", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "PODXL", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKACB", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURA", "PURB", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PXN", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSER1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB31", "RAB32", "RAB33B", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54B", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1CC1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMI1", "RMND1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF149", "RNF20", "RNF213", "RNF219", "RNF31", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCAMP4", "SCAP", "SCARA3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL1", "SCYL2", "SDAD1", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SELENOI", "SENP3", "SENP6", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGSH", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIAE", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG6", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMPDL3A", "SMPDL3B", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX25", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORL1", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPHK2", "SPOUT1", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSFA2", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STK3", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYDE1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TAX1BP1", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TCTN3", "TDRD7", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX2", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "TGOLN2", "TGS1", "THADA", "THAP11", "THEM6", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TIPRL", "TJP1", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM11", "TMEM115", "TMEM126B", "TMEM14C", "TMEM160", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM206", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMEM98", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIO", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2B", "TRMT5", "TRMT6", "TRMU", "TROVE2", "TRPC4AP", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSR2", "TSR3", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC38", "TTC39C", "TTC4", "TTF2", "TTI2", "TTK", "TTLL12", "TTLL4", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP1", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBIAD1", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "URGCP", "UROD", "USE1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP32", "USP33", "USP34", "USP36", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAC14", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VLDLR", "VMP1", "VPS11", "VPS13A", "VPS13C", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "VTI1B", "WAPL", "WARS", "WASF2", "WASHC3", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR70", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WLS", "WNK1", "WNK2", "WRN", "WRNIP1", "WTAP", "WWP2", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCCHC9", "ZDHHC13", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF131", "ZNF277", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512", "ZNF622", "ZNF638", "ZNF644", "ZNF687", "ZNF830", "ZPR1", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["ABCC1", "ABCD4", "ACP2", "ADCY3", "ADGRE5", "ADO", "ADPGK", "AGPS", "AIFM1", "AKT2", "ANKLE2", "ANO6", "APLP2", "APOL2", "APP", "ARSA", "ARV1", "ASAH1", "ATG9A", "ATP13A1", "ATP13A2", "ATP13A3", "ATP1B1", "ATP2C1", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP7A", "ATRN", "B3GAT3", "B4GALT3", "B4GAT1", "BCAP29", "BRAP", "BSG", "BTN2A1", "C1QBP", "C3orf58", "C5orf15", "CADM1", "CALM3", "CANT1", "CASK", "CD109", "CD276", "CD320", "CD47", "CERS1", "CERS2", "CHKA", "CHPF2", "CHST14", "CLCN3", "CLCN7", "CLN5", "CLN6", "CLPP", "CLSTN3", "CNNM3", "CNNM4", "COA3", "COCH", "COLEC12", "COMT", "COX15", "CPD", "CPE", "CPT2", "CPVL", "CREG1", "CRTAP", "CSGALNACT2", "CSNK2B", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CUTA", "CXADR", "CYB5B", "CYB5D2", "CYP20A1", "CYP51A1", "DAG1", "DAGLB", "DCTPP1", "DHCR24", "DHCR7", "DHFR", "DIABLO", "DIP2B", "DNAJC1", "DNASE2", "DOLPP1", "DSC3", "DSG2", "ECE1", "ECHDC1", "EFCAB14", "EGFR", "EHMT1", "EHMT2", "EMD", "ENPP4", "ENTPD7", "EPDR1", "EPHA2", "EPHA7", "EPHX2", "ERGIC3", "F11R", "FAM234B", "FAT1", "FBXO38", "FCGRT", "FECH", "FKBP14", "FKBP7", "FKRP", "FMR1", "FREM2", "FTL", "FUCA1", "FUCA2", "FUS", "FXR1", "GAA", "GALNS", "GALNT7", "GBA", "GBE1", "GGH", "GGT7", "GLA", "GLB1", "GLG1", "GLT8D1", "GM2A", "GNAI2", "GNAI3", "GNAO1", "GNS", "GOLIM4", "GOSR1", "GPAM", "GPD2", "GPR107", "GPR108", "GRB2", "GTF3C1", "GUSB", "HCCS", "HEXA", "HEXB", "HLA-A", "HLA-B", "HLA-C", "HMOX2", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HPS6", "HS2ST1", "HSD17B7", "HSDL1", "ICMT", "IDH1", "IDH2", "IFNGR1", "IGF2BP2", "IGF2R", "IMPAD1", "IRS4", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "JAK1", "KDELR1", "KDM1B", "KDSR", "KEAP1", "KIAA0319L", "KIAA1549", "KIAA2013", "KIDINS220", "KIFBP", "KIRREL1", "LAMP1", "LAMP2", "LDLR", "LGALS3BP", "LGMN", "LIPA", "LNPEP", "LRIG2", "LRP1", "LRP2", "LYSMD3", "M6PR", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MANEA", "MAP4K4", "MCAM", "MCL1", "METTL7B", "MFGE8", "MFSD8", "MGRN1", "MIA2", "MIF", "MMGT1", "MOCOS", "MPV17L2", "MRC2", "MSMO1", "MSTO1", "MTMR4", "NAA40", "NAGLU", "NCAM1", "NCOA4", "NCSTN", "NDC1", "NDUFA8", "NDUFB10", "NDUFB3", "NECTIN2", "NEDD4", "NEO1", "NEU1", "NFKBIL1", "NID1", "NISCH", "NNT", "NOTCH2", "NPC1", "NPC2", "NRDC", "NRM", "NRP1", "NSUN2", "NTMT1", "NUCB2", "OCLN", "OPA3", "OSTM1", "P3H1", "P4HA2", "PALD1", "PAM", "PANX1", "PCDH7", "PCYOX1", "PEX16", "PGRMC2", "PHF8", "PHIP", "PHKB", "PI4K2A", "PI4K2B", "PIK3R2", "PKMYT1", "PLA2G15", "PLD3", "PLXNA3", "PLXNB2", "PODXL", "POFUT2", "PPT1", "PPT2", "PRCP", "PREPL", "PRKACA", "PRKACB", "PRKAR1A", "PRKCA", "PROCR", "PSAP", "PSMB2", "PTPRF", "QSOX2", "RALA", "RBMX", "REEP4", "RNASET2", "RNF149", "ROBO1", "RRM2B", "RTN4IP1", "SAP130", "SC5D", "SCAMP2", "SCARA3", "SCARB1", "SCARB2", "SCPEP1", "SEZ6L2", "SFXN2", "SGPL1", "SGSH", "SIAE", "SLC12A2", "SLC12A9", "SLC19A1", "SLC25A15", "SLC25A32", "SLC2A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A6", "SLIT2", "SMPDL3A", "SMPDL3B", "SNAP29", "SNX25", "SOAT1", "SORL1", "SORT1", "SPHK2", "SPTLC1", "SQSTM1", "SSR1", "STARD3NL", 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file diff --git a/protein_atlas_subcellular_location_all/advanced/plot_0.png b/protein_atlas_subcellular_location_all/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..6d1ef287137dd0fa7f075450bddaf4691a366d82 --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4146320ce0981ebb79a1a2f326a148ebe6afd9fb62b04e2cc72560cf816b1fdb +size 200297 diff --git a/protein_atlas_subcellular_location_all/basic/idx2term.json b/protein_atlas_subcellular_location_all/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9d215a1fd39da85600c4c88ddc882cadb97601d8 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Cell Junctions", "1": "Centriolar satellite", "2": "Golgi apparatus", "3": "Cytokinetic bridge", "4": "Intermediate filaments", "5": "Focal adhesion sites"} \ No newline at end of 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0000000000000000000000000000000000000000..7e947f331fcb89a06c67f11c2229ea9c60d4e058 --- /dev/null +++ b/protein_atlas_subcellular_location_all/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3d81657b61b6c8d70f76d19b6bc842ba687e72bd7a0316aaecbd80f618c36826 +size 95208 diff --git a/protein_atlas_subcellular_location_all/df_merge.tsv b/protein_atlas_subcellular_location_all/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..550e4d1a639267da32cc96732e48edc0d30d14b9 --- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Lysosomes 4 14 2.349929039226395 0.0187769903768928 3.070388349514563 12.849514563106796 0.5262633691996788 0.494935559010686 2.4420262247147067 1.0913048915370858 0.8749364663493571 0.309114949195179 0.0001193358554663 1.0 0.014058804472369 0.0101015401572799 0.0017273216459823 +Cell Junctions 12 68 2.1526217371262315 0.0313484187693424 10.20388349514563 48.779126213592235 0.0528444018541478 0.6962606359612301 5.43694521473042 8.010142309536178 0.7104622417864562 0.2975972437396429 0.0243800435329717 0.6404961136303807 0.1365093862059673 0.1255426512850092 0.0752385080730694 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..dc10a486411a4a94937fd7c2d6b24865e387f8f8 --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3725, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 173.27272727272728 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d493103ebcc69f46b97f2d4985de157fb8447ee7 --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C170/C170_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a325a7e2b54f6e427cfbfb87a2b08a18792e64a9 --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,10 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Lysosomes 0.7516133181454346 2.349929039226395 0.0187769903768928 0.4650232765234753 0.2065468941458212 14 P02786,Q8WTV0,Q9NUM4,Q8IY95 4 +Cell Junctions 0.4974944072098928 2.1526217371262315 0.0313484187693424 0.6504329193200103 0.2307670449456086 68 Q9BY67,Q14574,P29317,Q16625,Q5KU26,P00533,O43657,P78310,Q92692,Q9Y624,O60245,Q99519 12 +Endosomes 0.6435621921432 1.799052615255884 0.0720103581763791 0.9150969589277684 0.3082910118765687 14 P02786,O14964,Q9NUM4,Q8IY95 4 +Centriolar satellite 0.5052404316175637 1.7274918541477828 0.0840793668754278 0.9448800513036352 0.3082910118765687 35 Q86UY6,P33176,Q00013,O43169,O00592,Q14145,P98155 7 +Golgi apparatus 0.5683260388125733 1.151010017286475 0.2497281144640128 0.999923754151905 0.6077847775038547 226 Q92485,Q93050,Q99523,P07711,P33908,Q8NC54,Q86SF2,O00461,Q9HB40,P80303,Q9Y287,Q9NX62,Q5KU26,O75955,P05067,Q5VW38,P19021,Q9UEU0,Q5BKZ1,O95456,P16278,Q9HD45,P50897,P15289,Q16706,P53365,O15127,Q8IUH4,Q6ZRP7,Q92520,Q8IZA0,P24390,O94898,P11717,Q13772,O15260,Q8N4Q0,Q8IYS2,Q92896,P04439,Q99640,O60637,Q8WVQ1,Q86Y82,P29317,O75071,Q8NCH0,Q04656,P10586,Q8NBN3,O43493,Q15043,O15212,O43752,Q5SRI9,Q92859,Q96C57,Q8NBJ4,O60512,Q9NPR9,Q93100,O43760,Q8IXU6,Q9H9S5,A4D1U4 65 +Cytokinetic bridge 0.4219258830465869 0.979442191049952 0.3273615389994824 0.9999979260609956 0.6077847775038547 32 Q9BVA1,Q6PIJ6,P22694,O43663,P07437,P17612,Q9Y2I1,P98155 8 +Intermediate filaments 0.3679725331587821 0.5994233056093693 0.548890639498711 0.999999999996098 0.7875387436285852 41 Q3SXM5,O75718,Q86YN1,Q96K76,O43164,Q9HCM3,Q13049 7 +Focal adhesion sites 0.3581120356661691 0.4928573584895697 0.6221133788248712 0.9999999999999888 0.8554058958841978 33 P06756,P11233,Q9Y487,O60888,Q9Y6M7 5 +Midbody ring 0.301711570115369 0.0111809946612228 0.9910790428608216 1.0 1.0 7 Q02241 1 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9267f763dfd9f9443e20c522fae9603ff25aaa77 --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAK1", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABCB1", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADGRE5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFF4", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG5", "ALG9", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKRD52", "ANKS1A", "ANLN", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APBB1", "APC", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARID1A", "ARID2", "ARID3B", "ARID4B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL6IP6", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC5", "ARSA", "ARV1", "ARVCF", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASNSD1", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATM", "ATP13A1", "ATP13A3", "ATP1B3", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATPAF1", "ATPIF1", "ATRN", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B4GALT3", "BABAM1", "BABAM2", "BAG2", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANF1", "BANP", "BAP1", "BAP18", "BARD1", "BASP1", "BAZ1B", "BAZ2A", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C15orf40", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2CD2", "C2CD5", "C2orf49", "C5orf15", "C5orf24", "C5orf51", "C8orf33", "CAB39", "CABIN1", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP8", "CAST", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX4", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC137", "CCDC138", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCDC97", "CCNB1", "CCNK", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD109", "CD276", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC123", "CDC20", "CDC27", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK7", "CDK9", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPI", "CENPU", "CENPV", "CEP170", "CEP250", "CEP290", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD5", "CHD8", "CHEK1", "CHEK2", "CHID1", "CHKA", "CHM", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLINT1", "CLK2", "CLK3", "CLN6", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT2", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COCH", "COG3", "COG7", "COG8", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ5", "COQ8A", "CORO1B", "COTL1", "COX15", "COX4I1", "COX5B", "COX6C", "COX7A2L", "CPD", "CPE", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CREG1", "CRK", "CRKL", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTBS", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTSF", "CTSL", "CTTN", "CTU2", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAKD", "DCP1A", "DCP1B", "DCP2", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DMAP1", "DMXL1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK6", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSCR3", "DSG2", "DSP", "DST", "DTX3L", "DTYMK", "DUS2", "DUS3L", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EGFR", "EHD1", "EHD4", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4ENIF1", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELP1", "ELP2", "ELP3", "ELP4", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENTPD7", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA2", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAHD1", "FAM105A", "FAM114A2", "FAM120A", "FAM120B", "FAM162A", "FAM177A1", "FAM192A", "FAM208A", "FAM234B", "FAM3C", "FAM49B", "FAM50A", "FAM83D", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXO21", "FBXO38", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FN3KRP", "FNBP1", "FNBP4", "FNDC3A", "FOCAD", "FOXC1", "FOXK1", "FOXK2", "FOXRED1", "FREM2", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALE", "GALK1", "GALNS", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGPS1", "GGT7", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GIT1", "GLB1", "GLB1L2", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR2", "GOT1", "GPAA1", "GPAM", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRAMD1A", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXIM1", "HGH1", "HGS", "HIBCH", "HIKESHI", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "IAH1", "IARS", "IARS2", "IBA57", "ICE1", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IFIT5", "IFNGR1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "IRGQ", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2B", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JCAD", "JPT2", "JUP", "KANK2", "KARS", "KAT5", "KAT7", "KATNA1", "KCTD10", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDM5B", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0100", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA1549", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFAP3", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LACTB", "LAMC1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDB1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRIG1", "LRIG2", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRR1", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8C", "LRWD1", "LSG1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSM8", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LYSMD3", "LZIC", "LZTFL1", "MACF1", "MACROD1", "MAD2L1BP", "MAGED1", "MAGED2", "MAIP1", "MAK16", "MAN1A1", "MAN2A1", "MAN2B1", "MANBA", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBLAC2", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED21", "MED23", "MED25", "MED27", "MEN1", "MEPCE", "MESD", "METAP2", "METTL13", "METTL15", "METTL17", "METTL7B", "MFAP1", "MFF", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD8", "MGA", "MGAT2", "MGEA5", "MGRN1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKL2", "MKRN2", "MMAB", "MMS19", "MMS22L", "MOCOS", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS18B", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFP1", "MTFR1", "MTFR1L", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA4", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFB11", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4", "NEFL", "NEFM", "NELFA", "NELFCD", "NELFE", "NEMF", "NEO1", "NEPRO", "NES", "NEU1", "NF1", "NF2", "NFATC2IP", "NFKBIL1", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME3", "NME4", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NRM", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSUN2", "NSUN5", "NT5C3A", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NUSAP1", "NVL", "NXF1", "OAT", "OBSL1", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC1", "ORC2", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSTM1", "OTUB1", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PALLD", "PAM", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCDH7", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF2", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4K2B", "PI4KA", "PI4KB", "PIAS1", "PIBF1", "PICALM", "PIGO", "PIGU", "PIK3C2A", "PIK3R4", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLCG1", "PLCG2", "PLD3", "PLEC", "PLEKHA5", "PLEKHA7", "PLIN3", "PLOD1", "PLOD2", "PLPBP", "PLRG1", "PLS3", "PLXNA3", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNMA1", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "PODXL", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIL2", "PPIL3", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKAA1", "PRKAA2", "PRKACA", "PRKACB", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUF60", "PUM1", "PUM3", "PURB", "PUS1", "PUS7", "PWP1", "PWP2", "PXN", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSER1", "QSOX2", "QTRT2", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB32", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAD54L2", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1CC1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMI1", "RMND1", "RNASEH2A", "RNASEH2B", "RNF14", "RNF149", "RNF20", "RNF213", "RNF219", "RNF31", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROBO1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCAMP4", "SCARA3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD2", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL1", "SDAD1", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SENP3", "SENP6", "SEPHS1", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3PXD2B", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC9A6", "SLFN11", "SLIRP", "SLK", "SLTM", "SLU7", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG6", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMPDL3A", "SMPDL3B", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNTB2", "SNW1", "SNX1", "SNX17", "SNX2", "SNX25", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPCS2", "SPDL1", "SPECC1L", "SPEN", "SPHK2", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSFA2", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STK3", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRIP1", "STT3B", "STUB1", "STX12", "STX18", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYDE1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TAX1BP1", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCTN3", "TDRD7", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TENM3", "TERF2IP", "TES", "TEX10", "TEX2", "TEX264", "TFAM", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "TGOLN2", "TGS1", "THADA", "THAP11", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM9", "TIMMDC1", "TIPRL", "TJP1", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TM9SF3", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMEM106B", "TMEM109", "TMEM11", "TMEM115", "TMEM126B", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM70", "TMEM87A", "TMEM97", "TMEM98", "TMF1", "TMLHE", "TMOD3", "TMPPE", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIO", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2B", "TRMT5", "TRMT6", "TRMU", "TROVE2", "TRPC4AP", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSR2", "TSR3", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC37", "TTC38", "TTC39C", "TTC4", "TTF2", "TTI2", "TTK", "TTLL12", "TTLL4", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWF2", "TWISTNB", "TXLNA", "TXLNG", "TXNDC16", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP1", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBIAD1", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "URGCP", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP22", "USP24", "USP28", "USP32", "USP33", "USP34", "USP36", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAC14", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VLDLR", "VMP1", "VPS11", "VPS13C", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "VTI1B", "WAPL", "WARS", "WASF2", "WASHC3", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR41", "WDR45B", "WDR46", "WDR48", "WDR5", "WDR6", "WDR70", "WDR74", "WDR77", "WDR82", "WIPI2", "WIZ", "WLS", "WNK1", "WNK2", "WRN", "WRNIP1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCCHC9", "ZDHHC13", "ZFR", "ZFYVE16", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF131", "ZNF277", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF503", "ZNF512", "ZNF622", "ZNF638", "ZNF644", "ZNF687", "ZNF830", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["APP", "ARFIP2", "ARSA", "ATP6V0A1", "ATP6V0A2", "ATP7A", "B4GALT3", "C12orf43", "C5orf15", "CADM1", "CANT1", "CHST14", "COLEC12", "CRTAP", "CTSL", "CUTA", "CXADR", "CYB5B", "DOLPP1", "DSC3", "EFCAB14", "EGFR", "EPHA2", "F11R", "FAM3C", "FBXO38", "FKRP", "FLOT1", "GALNT7", "GLB1", "GLG1", "GOLIM4", "GOLM1", "GPR107", "GPR108", "HGS", "HLA-A", "HSDL1", "IGF2R", "IMPAD1", "ITGAV", "ITM2B", "KDELR1", "KEAP1", "KIAA0319L", "KIAA1147", "KIAA1549", "KIAA2013", "KIF23", "KIF5B", "LRIG2", "MAN1A1", "MAN2A1", "MANEA", "MPP1", "NAA40", "NCOA4", "NECTIN2", "NEO1", "NEU1", "NISCH", "NUCB2", "OCLN", "PAM", "PCDH7", "PFDN6", "PHKB", "PJA2", "PKMYT1", "PODXL", "PPT1", "PRC1", "PRKACA", "PRKACB", "PSMG1", "PTPRF", "QSOX2", "RALA", "SCAMP2", "SCARB1", "SCPEP1", "SLC35F2", "SLC39A14", "SLC4A7", "SMPDL3B", "SORT1", "STX12", "STX6", "SURF4", "SYNGR2", "TFRC", "TGOLN2", "TM9SF3", "TMEM106B", "TMEM192", "TMEM87A", "TRIM32", "TSPAN3", "TSPAN6", "TUBB", "TUBB2B", "USP47", "VLDLR", "VTI1B", "ZADH2", "ZDHHC13", "ZNF326"]} \ No newline at end of file