diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..62706394b90157033dd7d9aa5789a72b7dac16ff --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c17e0af349d45653b0c5bbce851ef5036f6ca9e722958e79531b1eee74fc74ec +size 83899 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..70a75e988d11c05091daaf0cabb0b8de98ec3a07 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Thiolase, active site [IPR020610] 0 5 2.3721247267248606 0.0176861192402888 2.5606796116504853 4.844660194174757 -0.5308970493980486 0.3952147264399792 1.6528021290928414 0.3622283127413132 1.0786004395841309 0.2880439628871515 0.0213958237580913 0.0238038053541035 0.0471521402185075 0.1154193350298319 0.2191219719972187 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..75a9e8fbb869c1f9f640a28dbc3ab2e7a8a9d158 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 56, + "title": "Average number of proteins per term", + "value": 2.375 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..bb1c3951bcf7c2637be588c38394e2f1362d1d23 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..304c51428ad7cbe6c3dc16b389c326edbf6eda97 --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Peptidase S9, serine active site [IPR002471] 0.8155936590100308 3.1536316906745685 0.0016125245540179 0.0864107985967443 0.0056438359390628 2 P48147 1 +Serine carboxypeptidase, serine active site [IPR018202] 0.7107340559137065 2.3805519203215457 0.0172867247711487 0.6233811260111631 0.0282977907844621 3 Q9HB40 1 +Tyrosine-protein kinase, active site [IPR008266] 0.5225306662582987 1.0486552926636838 0.2943367976385576 0.9999999966775504 0.3363849115869229 5 P07948,Q15375 2 +Cysteine peptidase, cysteine active site [IPR000169] 0.3032741824110737 0.1832339079998869 0.8546144899995332 1.0 0.8546144899995332 4 P17655 1 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..aa6d7c4a44944d776e922326d1a8c3217ad16037 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine proteases, trypsin family, histidine active site [IPR018114]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CHEK1", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP11", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAPK1", "MDH1", "MDH2", "MTMR2", "NCEH1", "NEK9", "NME1", "NME6", "OXCT1", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKCA", "PRKCB", "PRPF4B", "PRSS3", "PTK7", "PTPMT1", "PTPN1", "PTPN9", "RIPK1", "RNASET2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "VRK2", "YES1"], "leading_proteins": ["CAPN2", "EPHA7", "LYN", "PREP", "SCPEP1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..c96dda7ea6b0b97671027428bb5704d52bb1fe05 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ba3104a6618ded304bdd8397873a2ce8792ba958034244e670cda109177d49f7 +size 76162 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..719993bfa978c2b16b93afca20cd6da51a8f7431 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 29, + "title": "Average number of proteins per term", + "value": 4.275862068965517 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..bc4cd1c7e2bce98364c0a9d162be9f9aae750858 --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..711951d0c1292530fda8ba2c2a60fd672b90fb83 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Beta tubulin, autoregulation binding site [IPR013838] 0.7987055016181124 2.8054642136733534 0.0050244160294674 0.1359074039648069 0.0091067540534097 3 P07437,Q9BUF5 2 +Peptidase M16, zinc-binding site [IPR001431] 0.5041692408606522 0.9587056019413904 0.3377070755692077 0.999993536714444 0.3627224145002602 5 Q10713 1 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d0fe039a3039b7105b5a4fea8dd5ee95d9811086 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "AURKB", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CETN2", "CHEK1", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP14", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LPCAT2", "LYN", "MACF1", "MAPK1", "MCCC1", "MICU1", "MYH10", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "PA2G4", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKAA2", "PRKCA", "PRKCB", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "TKT", "TUBB", "TUBB2B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["PMPCA", "TUBB", "TUBB6"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..b6e6f9ec351d4ebe1da6e5b23b04dbcf0c607ec5 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Chaperonin TCP-1, conserved site [IPR002194]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..803b1762c00e9300fa19f345f4691560ec49293b --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:227f97f15030e5712524197532e07ec5018c3b92244930d8e16c6c31372d1937 +size 143704 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7710f7c506cd7ad7307f62941760c69154a23ee8 --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:50abf502b37941d3795ed1d2f0da763007653e3a37a7d363a867f72400e89c51 +size 151825 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d23a93fc894d5937334d0ead5e49fa6e2fcd7873 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proteasome beta-type subunit, conserved site [IPR016050] 4 8 2.319902151640954 0.0203461711625909 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 1.0 1.0 0.0039135152062846 1.828578586842436e-06 2.1795177811063544e-06 +Thiolase, conserved site [IPR020613] 0 6 2.0673903235303968 0.0386973893102846 2.844660194174758 5.844660194174757 -0.5424048525012372 0.3903098970250164 1.8394663723529816 0.3622283127413132 1.063196584101526 0.2860337389117996 0.025620981617811 0.028497516818446 0.0563150378970086 0.1368589802283267 0.2568211172904328 +Syntaxin/epimorphin, conserved site [IPR006012] 4 7 2.0042228753374065 0.0450461911984025 2.592233009708738 5.847087378640777 0.9961908981999794 0.2839139128702306 1.4759357288864456 1.4239341993278547 1.138258151200134 0.2914162845337057 1.0 1.0 1.0 1.0 0.002702316606903 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6250381ca3b330e24451eddd267560250df2d51d --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 277, + "title": "Average number of proteins per term", + "value": 2.6823104693140793 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8cb77cc2a4a7b1134acca43a14d5ba1b80a5c2fc --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..070a3fb9f15c4529b8588eda953a7ddd8ad559bb --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,33 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Haem oxygenase conserved site [IPR018207] 0.9757360077644788 3.885325579591973 0.0001021928410975 0.0279119220870896 0.001010979178001 2 P30519 1 +C-type lectin, conserved site [IPR018378] 0.8893561954060236 3.4992446156963273 0.0004665783239534 0.1212653956206191 0.0019852277159901 2 Q5KU26 1 +Histidine triad, conserved site [IPR019808] 0.7919767065674563 3.0396185004417435 0.0023687799444929 0.4815597083944705 0.006044108421827 2 Q9BX68 1 +Dynamin, GTPase region, conserved site [IPR019762] 0.7880944678097801 3.0207141341854107 0.0025217932243 0.5031260909967972 0.0062931236318117 2 P50570 1 +Tubulin, conserved site [IPR017975] 0.7987055016181124 2.8054642136733534 0.0050244160294674 0.7522342151074926 0.0107888623268409 3 P07437,Q9BUF5 2 +Malic enzyme, conserved site [IPR015884] 0.6988029763830537 2.572679827983734 0.0100914515129697 0.9397668348298154 0.0189410000123865 2 P48163 1 +Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.7445437672568705 2.5465489321432297 0.01087939576431 0.9516894606607946 0.0200906175114259 3 Q9Y2T2 1 +Heavy-metal-associated, conserved site [IPR017969] 0.6677450663215848 2.4106538106802744 0.0159239553364973 0.9882796981472268 0.0266770279624802 2 P35670 1 +Proteasome beta-type subunit, conserved site [IPR016050] 0.8106020977570756 2.319902151640954 0.0203461711625909 0.9966339440163666 0.0322564835921817 8 P28070,P49721,P28074,Q99436 4 +Profilin conserved site [IPR027310] 0.6014234875444899 2.053573225346738 0.0400170157774997 0.9999877820244688 0.0568446839506021 2 P07737 1 +3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.6398667784355403 2.0214738476271785 0.0432307369180777 0.9999951738756238 0.0604793642742805 3 Q16836 1 +Syntaxin/epimorphin, conserved site [IPR006012] 0.7508635535919209 2.0042228753374065 0.0450461911984025 0.9999971482255826 0.0626170163952091 7 Q13190,O15400,O60499,Q9P2W9 4 +Mini-chromosome maintenance, conserved site [IPR018525] 0.6817967649668069 1.6497865188299148 0.0989866070294378 0.9999999999997112 0.1218635117651301 6 P33993,Q14566,P33991,P25205 4 +GTP1/OBG, conserved site [IPR006074] 0.5105143966353963 1.5405482182551735 0.1234267788424348 1.0 0.1498503806790891 2 P55039 1 +DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514] 0.4752507279197702 1.335617562451915 0.1816743067754522 1.0 0.2150589016102576 2 P19387 1 +Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867] 0.4736331284374018 1.326164978120751 0.1847850569488316 1.0 0.2178104713822398 2 P13995 1 +Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.4726625687479926 1.3204917695361893 0.1866708821693603 1.0 0.2181765162907714 2 P29692 1 +Vinculin, conserved site [IPR000633] 0.4571336137172429 1.2295829430022769 0.2188533205939538 1.0 0.252593207518855 2 P35221 1 +Thiosulphate sulfurtransferase, conserved site [IPR001307] 0.4451633775477332 1.1594018883013135 0.2462924074425727 1.0 0.2819132101718705 2 P25325 1 +Intermediate filament protein, conserved site [IPR018039] 0.5542405329154374 1.111857580021968 0.2661993900658521 1.0 0.3022017665911518 8 P08670,P20700,P07196 3 +Ribosomal S11, conserved site [IPR018102] 0.4118408282109305 0.964416631801344 0.3348370870705885 1.0 0.3695214068468248 2 P62263 1 +Procollagen-lysine 5-dioxygenase, conserved site [IPR001006] 0.4359223300970926 0.921454482375132 0.3568131951652911 1.0 0.3922113296062922 3 O60568,Q02809 2 +Guanylate kinase, conserved site [IPR020590] 0.4609217095009493 0.8844967058099291 0.376428139927762 1.0 0.4105141525983861 4 Q00013 1 +4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900] 0.4037138049098834 0.7481278372883998 0.4543830526215882 1.0 0.4897436014637351 3 P61221 1 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.3957928802589027 0.7062881026818788 0.4800089905970288 1.0 0.5133686887852393 3 O15347,P26583 2 +Alcohol dehydrogenase, zinc-type, conserved site [IPR002328] 0.3422840504691016 0.5712961533461867 0.5677989087800908 1.0 0.5957587035306255 2 Q00796 1 +Heat shock protein Hsp90, conserved site [IPR019805] 0.3582524271844697 0.5148105322926748 0.6066854247557116 1.0 0.6341579722918192 3 P08238,P07900 2 +Glycoside hydrolase, family 29, conserved site [IPR018526] 0.3261080556454185 0.4861037756368961 0.626893590105623 1.0 0.6528177611250284 2 Q9BTY2 1 +Cullin, conserved site [IPR016157] 0.3866580310880811 0.4153364293126369 0.6778956365995534 1.0 0.6980561016285364 5 Q13617,Q93034,Q13616,Q13620 4 +FERM conserved site [IPR019747] 0.364497035278896 0.2693211771086781 0.7876825370648279 1.0 0.7963067984195523 9 Q9Y4F1,Q9Y2J2,P35241 3 +ABC transporter-like, conserved site [IPR017871] 0.3284254064067824 0.1837172967541507 0.8542352390227539 1.0 0.8573302942366045 12 Q03518,P33527,P08183 3 +Chaperonin TCP-1, conserved site [IPR002194] 0.3303079416531709 0.1478796361302752 0.8824377595085999 1.0 0.8824377595085999 8 P50991,Q99832,P17987,P48643,P40227,P78371,P50990 7 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..206860ae9df2d204d6d0afb3866f6469f304f235 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycerate/sugar phosphate transporter, conserved site [IPR021159]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinate dehydrogenase, cytochrome b subunit, conserved site [IPR018495]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APLP2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7A", "ATP7B", "BAG6", "BAK1", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BLM", "BMI1", "BOP1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDKAL1", "CECR2", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX38", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "EPS15", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FTL", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GFM2", "GLA", "GLB1", "GLB1L2", "GLO1", "GNPDA1", "GNS", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXD11", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPAD1", "IMPDH2", "INA", "ING5", "IQGAP1", "IQGAP2", "ITGAV", "IVD", "KDM2A", "KDSR", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MOCS1", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPST", "MRC2", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSD3", "NSF", "NTHL1", "NUBP1", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PHF2", "PHF3", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SDHC", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A2", "SLC27A4", "SLC2A1", "SLC37A4", "SLC4A2", "SLC5A6", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STMN1", "STOM", "STRN", "STRN4", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TM7SF2", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP13", "TSFM", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBFD1", "UHRF1", "USP10", "USP14", "USP19", "USP36", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", 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b/interpro_domain/df_merge.tsv @@ -0,0 +1,11 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 2 6 2.437837373618157 0.0147754195097253 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0506000729453915 0.0561990347849709 0.0056684159955205 0.00262770885776 0.0019443402252438 +Aminopeptidase N-like , N-terminal domain [IPR045357] 3 5 2.409587730095485 0.0159705558708798 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0340178825746634 0.0378187125466048 0.002465796513642 0.0007187465088185 0.0003209969829564 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 3 5 2.409587730095485 0.0159705558708798 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0340178825746634 0.0378187125466048 0.002465796513642 0.0007187465088185 0.0003209969829564 +Ubiquitin-like domain [IPR000626] 1 14 2.320088847614603 0.0203360715145177 4.405339805825243 14.820388349514564 -0.0462692019740876 0.6086089683072633 2.7436193640206525 2.317466779992568 0.7856205542108695 0.2846932444846588 0.1664042855086975 0.1835089509173778 0.3339976348230559 0.2707185745648809 0.330657476090698 +Pleckstrin homology domain [IPR001849] 6 18 2.306983832810712 0.0210557214112276 7.577669902912621 25.652912621359224 -0.0316373490872633 0.6250683324241235 5.069544167456597 6.588340411720883 0.8478431018941189 0.3044798814492656 0.5843592755764278 0.6239158458722325 0.8592353865109894 0.5397273111791803 0.858715396619645 +Polyketide synthase, enoylreductase domain [IPR020843] 0 5 2.170332120556613 0.0299816949809665 1.6189320388349515 6.283980582524272 0.4837477775906041 0.3583565743712875 1.2357658783365448 1.1656223303878015 1.2317099658487027 0.2921137785685181 0.0464807950838554 0.0516364610584135 0.1008375048293403 0.2365379696877526 0.4197545932587097 +Alcohol dehydrogenase, N-terminal [IPR013154] 0 5 2.150475086309434 0.0315176546029181 1.3762135922330097 5.245145631067961 0.6000738304798152 0.3870290227769069 1.1994000251783288 0.9246362329357484 1.1062357688130569 0.3020782188917261 0.0381897723637082 0.0424464003246627 0.0832836732680532 0.1981219124770219 0.359364707162026 +Thiolase, N-terminal [IPR020616] 0 6 2.0673903235303968 0.0386973893102846 2.844660194174758 5.844660194174757 -0.5424048525012372 0.3903098970250164 1.8394663723529816 0.3622283127413132 1.063196584101526 0.2860337389117996 0.025620981617811 0.028497516818446 0.0563150378970086 0.1368589802283267 0.2568211172904328 +Thiolase, C-terminal [IPR020617] 0 6 2.0673903235303968 0.0386973893102846 2.844660194174758 5.844660194174757 -0.5424048525012372 0.3903098970250164 1.8394663723529816 0.3622283127413132 1.063196584101526 0.2860337389117996 0.025620981617811 0.028497516818446 0.0563150378970086 0.1368589802283267 0.2568211172904328 +W2 domain [IPR003307] 0 6 1.981304085783813 0.0475571824720735 2.4320388349514563 6.949029126213592 -0.0117719676705937 0.4980037069590429 1.8676455034741433 0.2199382727309138 0.9626067339155384 0.2849905785043493 1.0 1.0 0.0653907127050202 0.1577810442013011 0.2927037483377068 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5d3d1acafd464e47d198668aaa2506d386b96edc --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 2494, + "title": "Average number of proteins per term", + "value": 2.1712109061748195 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..71b8d895c4d4371486dfcb606a65fe836d947ae8 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7b4e0fff7c748d3bb22747786c63d9499408d12e --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,235 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +FF domain [IPR002713] 0.9792947266256876 3.900830436322604 9.586328034938418e-05 0.212659510303386 0.0009226866269516 2 O14776 1 +Marvel domain [IPR008253] 0.966677450663217 3.845720339519346 0.0001201987949785 0.2590290160871513 0.0009827692170466 2 Q16625 1 +Prenylcysteine lyase [IPR010795] 0.963765771594954 3.832947607832933 0.0001266169276041 0.2707966271995953 0.0009827692170466 2 Q9UHG3 1 +Cysteine-rich flanking region, C-terminal [IPR000483] 0.9579424134584296 3.8073396599218863 0.0001404697554252 0.2955628598619376 0.0009897430699889 2 Q13641 1 +Leucine-rich repeat N-terminal domain [IPR000372] 0.9579424134584296 3.8073396599218863 0.0001404697554252 0.2955628598619376 0.0009897430699889 2 Q13641 1 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.9369136201876446 3.714163609860119 0.0002038768661876 0.3986154770785993 0.0012164327853394 2 P98179 1 +Choline/carnitine acyltransferase domain [IPR039551] 0.9252669039145954 3.6620764830298937 0.0002501791379947 0.4642163472978362 0.0013447305518158 2 P23786 1 +GINS subunit, domain A [IPR021151] 0.9113555483662252 3.599401617306415 0.0003189502726437 0.5486846064416051 0.0015845856174769 2 Q9BRX5 1 +GMP phosphodiesterase, delta subunit [IPR008015] 0.901326431575546 3.553902031440064 0.0003795605759147 0.6120208866549939 0.0017845104556796 2 A6NIH7 1 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.8984147525072829 3.5406423881383473 0.0003991541919026 0.6305313123237137 0.0018440435667733 2 Q32P28 1 +ERAP1-like C-terminal domain [IPR024571] 0.9530744336569544 3.499437009610122 0.0004662417507104 0.6874772727115981 0.0020202193401735 3 Q9UIQ6,P55786 2 +C-type lectin-like [IPR001304] 0.8893561954060236 3.4992446156963273 0.0004665783239534 0.687739620797584 0.0020202193401735 2 Q5KU26 1 +CD209-like, C-type lectin-like domain [IPR033989] 0.8893561954060236 3.4992446156963273 0.0004665783239534 0.687739620797584 0.0020202193401735 2 Q5KU26 1 +Peptidase S9A, N-terminal domain [IPR023302] 0.8634746036881353 3.3797309204166193 0.0007255682703113 0.8363825284456365 0.0026808403943058 2 Q4J6C6 1 +Dbl homology (DH) domain [IPR000219] 0.8563571659657068 3.34653809304833 0.0008182743577673 0.8701806826040384 0.0029066483314779 2 Q9Y4F1 1 +CELF1/2, RNA recognition motif 3 [IPR034199] 0.8450339695891322 3.293435344913217 0.0009897110109813 0.9153780457212296 0.0033337382851296 2 Q92879 1 +CELF1/2, RNA recognition motif 2 [IPR034198] 0.8450339695891322 3.293435344913217 0.0009897110109813 0.9153780457212296 0.0033337382851296 2 Q92879 1 +CELF1/2, RNA recognition motif 1 [IPR034196] 0.8450339695891322 3.293435344913217 0.0009897110109813 0.9153780457212296 0.0033337382851296 2 Q92879 1 +Cold-shock (CSD) domain [IPR019844] 0.8997244188848144 3.266555971702029 0.0010886428485843 0.9338978635698952 0.0035491179926396 3 P16989 1 +Cold-shock protein, DNA-binding [IPR002059] 0.8997244188848144 3.266555971702029 0.0010886428485843 0.9338978635698952 0.0035491179926396 3 P16989 1 +Cold shock domain [IPR011129] 0.8997244188848144 3.266555971702029 0.0010886428485843 0.9338978635698952 0.0035491179926396 3 P16989 1 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.8372694920737631 3.256809565220669 0.0011267199651086 0.939892691967556 0.0036446687327896 2 O43390 1 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.8359754124878688 3.250688315916422 0.0011512599548171 0.9434650569016388 0.0037000545455076 2 P10321 1 +MHC class I, alpha chain, C-terminal [IPR010579] 0.8359754124878688 3.250688315916422 0.0011512599548171 0.9434650569016388 0.0037000545455076 2 P10321 1 +Ras-associating (RA) domain [IPR000159] 0.8223875768359841 3.186119932582343 0.0014419480838614 0.9726438468262666 0.0043643428654738 2 Q9Y4G8 1 +Class II aldolase/adducin N-terminal [IPR001303] 0.8146230993206149 3.148979308920101 0.0016384179537023 0.9832534916790784 0.0047458935848242 2 Q9UEY8 1 +RBM1CTR [IPR012604] 0.814299579424139 3.1474278904448867 0.001647137276074 0.9836143163489132 0.0047600931245986 2 Q96E39 1 +FAD-binding domain, PCMH-type [IPR016166] 0.7958589453251437 3.0584766278508546 0.0022246543188777 0.9961298753023856 0.0059530985743359 2 Q15392 1 +FAD linked oxidase, N-terminal [IPR006094] 0.7958589453251437 3.0584766278508546 0.0022246543188777 0.9961298753023856 0.0059530985743359 2 Q15392 1 +Metaxin, glutathione S-transferase domain [IPR033468] 0.7952119055321967 3.055336808556591 0.0022480790713403 0.9963499734150288 0.0059733597758896 2 Q13505 1 +Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.7952119055321967 3.055336808556591 0.0022480790713403 0.9963499734150288 0.0059733597758896 2 Q13505 1 +Dynamin GTPase effector [IPR003130] 0.7880944678097801 3.0207141341854107 0.0025217932243 0.9981587229182324 0.0064705270590578 2 P50570 1 +Dynamin stalk domain [IPR000375] 0.7880944678097801 3.0207141341854107 0.0025217932243 0.9981587229182324 0.0064705270590578 2 P50570 1 +GTPase effector domain [IPR020850] 0.7880944678097801 3.0207141341854107 0.0025217932243 0.9981587229182324 0.0064705270590578 2 P50570 1 +Ancestral coatomer element 1, Sec16/Sec31 [IPR024298] 0.7877709479132955 3.0191366764580425 0.0025349614207059 0.9982183593218432 0.0064909587096927 2 O94979 1 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.8436219528831881 3.013871729591933 0.0025793683503834 0.998405596233722 0.0065843855331179 3 P52888 1 +Chromatin target of PRMT1 protein, C-terminal [IPR025715] 0.7842122290520932 3.0017633154634034 0.0026842078444484 0.9987732845827734 0.0068032666301366 2 Q9Y3Y2 1 +GRAM domain [IPR004182] 0.8281330681151207 2.942634215659296 0.0032543268484528 0.9997052922629333 0.0078752757457865 3 Q66K14 1 +PABP, RNA recognition motif 2 [IPR045305] 0.7699773536072492 2.9318761278047507 0.0033692110371918 0.9997789230277604 0.0080332813831325 2 P11940 1 +Agenet-like domain [IPR008395] 0.7670656745389843 2.917502792878253 0.0035284648883497 0.9998515931811272 0.0082706686386695 2 P51114 1 +Fxr1, tudor domain [IPR041560] 0.7670656745389843 2.917502792878253 0.0035284648883497 0.9998515931811272 0.0082706686386695 2 P51114 1 +Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.7670656745389843 2.917502792878253 0.0035284648883497 0.9998515931811272 0.0082706686386695 2 P51114 1 +Fragile X-related 1 protein, C-terminal core [IPR022034] 0.7670656745389843 2.917502792878253 0.0035284648883497 0.9998515931811272 0.0082706686386695 2 P51114 1 +Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346] 0.7664186347460454 2.914305086133921 0.0035648133957446 0.9998644986717246 0.0083480231070302 2 Q8WXI9 1 +MATH/TRAF domain [IPR002083] 0.7648010352636692 2.9063050294447845 0.0036572473802995 0.9998924865865174 0.0084769284074974 2 O43791 1 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.7602717567130353 2.88386075744301 0.0039283240805645 0.9999454577086644 0.0090297145225142 2 Q9NVI7 1 +KHDRBS, Qua1 domain [IPR032571] 0.7550954383694581 2.8581302277003995 0.0042614545989607 0.9999763175863532 0.009582486157037 2 O75525 1 +Sam68, tyrosine-rich domain [IPR032335] 0.7550954383694581 2.8581302277003995 0.0042614545989607 0.9999763175863532 0.009582486157037 2 O75525 1 +Exosome complex component, N-terminal domain [IPR025721] 0.7544483985765227 2.854907894014324 0.0043049311743255 0.9999787610719506 0.0096638148953805 2 Q9Y3B2 1 +Ion transporter-like, CBS domain [IPR044751] 0.7473309608540951 2.8193735599714325 0.0048117483752798 0.999994034186264 0.0105175288763786 2 Q6P4Q7 1 +CNNM, transmembrane domain [IPR002550] 0.7473309608540951 2.8193735599714325 0.0048117483752798 0.999994034186264 0.0105175288763786 2 Q6P4Q7 1 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.7987055016181124 2.8054642136733534 0.0050244160294674 0.9999964990620308 0.0108869622741023 3 P07437,Q9BUF5 2 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.7987055016181124 2.8054642136733534 0.0050244160294674 0.9999964990620308 0.0108869622741023 3 P07437,Q9BUF5 2 +U2A'/phosphoprotein 32 family A, C-terminal [IPR003603] 0.7295373665480439 2.729820274945346 0.0063368862065904 0.999999869837406 0.01300756724217 2 P09661 1 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.8350885426944858 2.7221422020047137 0.0064860226274492 0.9999999104821494 0.0132374307961198 4 Q96CP7 1 +Peptidase M41 [IPR000642] 0.7275962471692083 2.7199882647370353 0.0065284233166513 0.9999999195208532 0.0133021958755952 2 Q96TA2 1 +Ras GTPase-activating domain [IPR001936] 0.7799545032798787 2.7167867192594 0.0065919071342124 0.9999999313772616 0.0133660295875819 3 Q14C86 1 +Peptidase M16, middle/third domain [IPR032632] 0.7243610482044734 2.703574030425329 0.0068598165413851 0.9999999649795052 0.0138193719339373 2 O43847 1 +Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004] 0.7702265372168189 2.670383368433333 0.0075764687763797 0.9999999942130366 0.0149847050977724 3 O95071,P11940 2 +BAG domain [IPR003103] 0.8215445776107604 2.661321225152714 0.0077834661789493 0.9999999965603812 0.015297056462017 4 O95817,O95429 2 +UAS [IPR006577] 0.7149789712067307 2.6557771365350145 0.0079125887440301 0.9999999975137348 0.0154776441785185 2 Q96CS3 1 +Intermediate filament head, DNA-binding domain [IPR006821] 0.8173779903552698 2.6425163777719853 0.0082292485257611 0.9999999988785682 0.0160091621086179 4 P08670 1 +OCRE domain [IPR041591] 0.7638252356750697 2.6396988419932264 0.0082979728956185 0.999999999056558 0.0160348918615177 3 P78332 1 +Glutamine amidotransferase type 2 domain [IPR017932] 0.7110967324490467 2.635913601638519 0.0083911093843607 0.999999999253573 0.0161726636820677 2 Q06203 1 +Dynamin, GTPase domain [IPR001401] 0.7582524271844526 2.612888379809722 0.0089780618923085 0.9999999998295208 0.0169800056310768 3 O00429,P50570 2 +Zinc finger C2H2 AKAP95-type [IPR034736] 0.757740625559612 2.6104215762560097 0.0090430703737289 0.99999999985525 0.0170729882756094 3 Q9ULX6 1 +Malic enzyme, NAD-binding [IPR012302] 0.6988029763830537 2.572679827983734 0.0100914515129697 0.9999999999896696 0.0184381538998875 2 P48163 1 +Malic enzyme, N-terminal domain [IPR012301] 0.6988029763830537 2.572679827983734 0.0100914515129697 0.9999999999896696 0.0184381538998875 2 P48163 1 +N-acetylgalactosaminyltransferase [IPR045885] 0.6939501779359429 2.5475792076169967 0.0108473225031371 0.9999999999984628 0.0194069026706054 2 Q86SF2 1 +Syntaxin, N-terminal domain [IPR006011] 0.738288369445296 2.5160932608181383 0.0118663778401062 0.9999999999998824 0.020944618777937 3 O15400 1 +Zinc finger, CHHC-type [IPR012996] 0.736569579288018 2.5077046610949028 0.0121518187129958 0.9999999999999428 0.0213577419804169 3 P52597,P31943 2 +Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375] 0.781304723228496 2.4778318747370727 0.0132183414613586 0.999999999999996 0.0228616807244303 4 Q4J6C6,P48147 2 +Far upstream element-binding protein, C-terminal [IPR015096] 0.678421222905216 2.466720909162221 0.0136356590158748 0.9999999999999988 0.023213196986752 2 Q96AE4 1 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.8606864150365539 2.437837373618157 0.0147754195097253 1.0 0.0245665975048367 6 Q8WUJ1,Q9UMX5 2 +Heavy metal-associated domain, copper ion-binding [IPR006122] 0.6677450663215848 2.4106538106802744 0.0159239553364973 1.0 0.0260080842234606 2 P35670 1 +Heavy metal-associated domain, HMA [IPR006121] 0.6677450663215848 2.4106538106802744 0.0159239553364973 1.0 0.0260080842234606 2 P35670 1 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.8099090261299893 2.4095877300954855 0.0159705558708798 1.0 0.0260500760902382 5 Q9UIQ6,Q9NZ08,P55786 3 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.8099090261299893 2.4095877300954855 0.0159705558708798 1.0 0.0260500760902382 5 Q9UIQ6,Q9NZ08,P55786 3 +UBX domain [IPR001012] 0.715210355987029 2.4027256980167024 0.0162733889853166 1.0 0.0264575176853843 3 Q92575,Q96CS3 2 +CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.7145631067960916 2.3995232080811157 0.0164164391334931 1.0 0.0266553380201379 3 Q96F07,Q9NUQ9 2 +Staufen, C-terminal [IPR032478] 0.709314035272841 2.373505136938313 0.0176201479498046 1.0 0.0283148511512968 3 O95793 1 +FCP1 homology domain [IPR004274] 0.6593335490132666 2.3662044146094696 0.0179715185970992 1.0 0.0286364622511479 2 Q3ZCQ8 1 +GNAT domain [IPR000182] 0.7560069910765328 2.36030851897797 0.0182597421650028 1.0 0.0289509198725473 4 Q86UY6 1 +CAP Gly-rich domain [IPR000938] 0.70619711875887 2.358016330935224 0.0183728846655204 1.0 0.0290748568247512 3 Q99426 1 +DNA2/NAM7 helicase, helicase domain [IPR041677] 0.7034310538042734 2.344246522511912 0.0190655649924627 1.0 0.0300375989205318 3 P42694 1 +Ubiquitin-like domain [IPR000626] 0.7153320213988524 2.320088847614603 0.0203360715145177 1.0 0.0315411457445319 14 P46379 1 +NOPS [IPR012975] 0.696440129449838 2.309342144461189 0.0209246027533152 1.0 0.0320946858959213 3 Q15233,Q8WXF1 2 +Pleckstrin homology domain [IPR001849] 0.664301345355604 2.3069838328107117 0.0210557214112276 1.0 0.0322759491085444 18 Q9BZF3,Q9Y4F1,P50570,Q9Y5P4,P31751,Q6WCQ1 6 +Peptidase M28 [IPR007484] 0.6866996952077804 2.260464371062669 0.0237924452934956 1.0 0.0356600712511888 3 Q7Z2K6 1 +Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906] 0.6334519572953776 2.2279082188406405 0.0258866360041436 1.0 0.0380219494666279 2 P51812 1 +ERM family, FERM domain C-lobe [IPR041789] 0.6786067914353339 2.2196363816853384 0.0264434605453112 1.0 0.0386576732708125 3 P35241 1 +DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.7096739982393361 2.1406705809515745 0.0323006125425755 1.0 0.0457150012254549 4 Q9HCE1,P42694 2 +Tyrosine-protein kinase, catalytic domain [IPR020635] 0.7076048640335092 2.1307294726780923 0.033111435556878 1.0 0.04644539948192 4 Q15375,P07948 2 +MHC class I-like antigen recognition-like [IPR011161] 0.6535958130653214 2.0922131332112723 0.0364194541888778 1.0 0.0500993484539775 3 P10321 1 +Immunoglobulin C1-set [IPR003597] 0.6535958130653214 2.0922131332112723 0.0364194541888778 1.0 0.0500993484539775 3 P10321 1 +3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108] 0.6398667784355403 2.0214738476271785 0.0432307369180777 1.0 0.0578109693692686 3 Q16836 1 +3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176] 0.6398667784355403 2.0214738476271785 0.0432307369180777 1.0 0.0578109693692686 3 Q16836 1 +HDGF-related, PWWP domain [IPR035496] 0.6394504561499439 2.019320026145722 0.0434539677436505 1.0 0.0579282901265272 3 Q7Z4V5 1 +Formin, FH2 domain [IPR015425] 0.5901002911679134 1.991102903051424 0.0464695753739781 1.0 0.0610938961426997 2 Q9Y613 1 +Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768] 0.5901002911679134 1.991102903051424 0.0464695753739781 1.0 0.0610938961426997 2 Q9Y613 1 +FAD dependent oxidoreductase [IPR006076] 0.6730917498609292 1.9632619862044436 0.0496157400819137 1.0 0.0643817147576965 4 Q96CU9 1 +Sterile alpha motif domain [IPR001660] 0.7360436133052086 1.9370328213447243 0.052741331440496 1.0 0.0678724874162008 7 Q15375,Q9Y3Z3,Q96JM7 3 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.7059649272393875 1.8879018238836691 0.0590391316571341 1.0 0.0747050199659526 9 O95302,Q9NWM8 2 +Target SNARE coiled-coil homology domain [IPR000727] 0.7047233500129543 1.8819870610839184 0.0598377724448417 1.0 0.0755239901201596 9 Q13190,O15400,O60499,Q8IZP0 4 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.6912494178694333 1.8670779165342728 0.061890707815114 1.0 0.0778001135538782 5 Q32P28 1 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.6912494178694333 1.8670779165342728 0.061890707815114 1.0 0.0778001135538782 5 Q32P28 1 +Cyclic nucleotide-binding domain [IPR000595] 0.686725236198906 1.8457460670721395 0.0649290849078565 1.0 0.0808048213913811 5 Q8IY17 1 +Coatomer subunit gamma, C-terminal [IPR032154] 0.5587188612099732 1.81575292645456 0.0694082812248217 1.0 0.0850635151718454 2 Q9UBF2 1 +Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040] 0.5587188612099732 1.81575292645456 0.0694082812248217 1.0 0.0850635151718454 2 Q9UBF2 1 +ATP-dependent RNA helicase Ski2, C-terminal [IPR012961] 0.5583953413134997 1.8139286896447528 0.0696887051223962 1.0 0.085281467406897 2 P42285 1 +rRNA-processing arch domain [IPR025696] 0.5583953413134997 1.8139286896447528 0.0696887051223962 1.0 0.085281467406897 2 P42285 1 +EF-hand, Ca insensitive [IPR014837] 0.5906148867313857 1.7632204518834755 0.0778633156762129 1.0 0.0930479680385601 3 Q13813,P12814 2 +WW domain [IPR001202] 0.6067976713416205 1.7344909985399264 0.0828310015260058 1.0 0.098138013209434 14 Q96J02,O75400,P46939,O14776,Q96PU5,O95817 6 +Chromo domain subgroup [IPR017984] 0.5851269828621092 1.7340300159995257 0.0829127575161114 1.0 0.0981416313456013 3 P83916 1 +Chromo shadow domain [IPR008251] 0.5851269828621092 1.7340300159995257 0.0829127575161114 1.0 0.0981416313456013 3 P83916 1 +Fzo/mitofusin HR2 domain [IPR006884] 0.5393076674215566 1.705730618431815 0.0880582461822179 1.0 0.1036419376962961 2 Q8IWA4 1 +Glycosyl transferase CAP10 domain [IPR006598] 0.5367195082497621 1.690976054760074 0.0908413760563107 1.0 0.1067161525597922 2 Q6UW63 1 +Zinc finger, UBP-type [IPR001607] 0.5351019087673996 1.6817446501089433 0.0926183658317327 1.0 0.1085990617697891 2 P45974 1 +Rad60/SUMO-like domain [IPR022617] 0.5325137495956074 1.6669588969010027 0.0955225782476629 1.0 0.1118466244834138 2 P61956 1 +MCM, AAA-lid domain [IPR041562] 0.6817967649668069 1.6497865188299148 0.0989866070294378 1.0 0.1155770589566563 6 P33993,Q14566,P33991,P25205 4 +MCM N-terminal domain [IPR027925] 0.6817967649668069 1.6497865188299148 0.0989866070294378 1.0 0.1155770589566563 6 P33993,Q14566,P33991,P25205 4 +MCM domain [IPR001208] 0.6817967649668069 1.6497865188299148 0.0989866070294378 1.0 0.1155770589566563 6 P33993,Q14566,P33991,P25205 4 +MCM OB domain [IPR033762] 0.6817967649668069 1.6497865188299148 0.0989866070294378 1.0 0.1155770589566563 6 P33993,Q14566,P33991,P25205 4 +Legume-like lectin [IPR005052] 0.5244257521837664 1.620633143236596 0.1050963397842648 1.0 0.1221959307328468 2 P49257 1 +GTP binding protein, second domain [IPR031662] 0.5105143966353963 1.5405482182551735 0.1234267788424348 1.0 0.1422487922518634 2 P55039 1 +SGS domain [IPR007699] 0.4936913620187716 1.4430864335920468 0.1489961244849273 1.0 0.1706135603606101 2 Q9HB71 1 +IPT domain [IPR002909] 0.4914267227434523 1.4299209155847037 0.1527397183039101 1.0 0.1747398428669503 2 Q96KP1 1 +RING-type zinc-finger, LisH dimerisation motif [IPR027370] 0.4791329666774577 1.3582888030930502 0.1743720617679918 1.0 0.1984865002507401 2 O15344 1 +DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263] 0.4752507279197702 1.335617562451915 0.1816743067754522 1.0 0.206140000499535 2 P19387 1 +DNA-directed RNA polymerase, insert domain [IPR011262] 0.4752507279197702 1.335617562451915 0.1816743067754522 1.0 0.206140000499535 2 P19387 1 +Elongation factor 1 beta central acidic region, eukaryote [IPR018940] 0.4726625687479926 1.3204917695361893 0.1866708821693603 1.0 0.211520754261874 2 P29692 1 +Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038] 0.4726625687479926 1.3204917695361893 0.1866708821693603 1.0 0.211520754261874 2 P29692 1 +Mu homology domain [IPR028565] 0.5424718246904008 1.3045558504405212 0.1920441300364808 1.0 0.2174117386795202 4 Q9Y2T2 1 +Zinc finger, RanBP2-type [IPR001876] 0.6003790102394493 1.302722070253677 0.1926696644005927 1.0 0.2180209360322496 7 Q92804,P35637,P98175 3 +Stromalin conservative domain [IPR020839] 0.4671627305079266 1.2883219896003315 0.1976339016041803 1.0 0.2232332203808088 2 Q8WVM7 1 +STAG [IPR013721] 0.4671627305079266 1.2883219896003315 0.1976339016041803 1.0 0.2232332203808088 2 Q8WVM7 1 +MRH domain [IPR044865] 0.5366292279289286 1.2744268338663929 0.2025121874200075 1.0 0.2286398349594834 4 P20645,P11717 2 +Protein kinase, C-terminal [IPR017892] 0.5836027931268395 1.2225928393289356 0.2214835190485649 1.0 0.2481490999582753 7 P31751 1 +AGC-kinase, C-terminal [IPR000961] 0.5836027931268395 1.2225928393289356 0.2214835190485649 1.0 0.2481490999582753 7 P31751 1 +Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.4532513749595626 1.2068266188935255 0.2274989224526877 1.0 0.2543174865965949 2 O60884 1 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.5614042126547141 1.180271272883491 0.2378923398345271 1.0 0.2643954971244701 9 Q9HD20 1 +DNA mismatch repair protein MutS, clamp [IPR007861] 0.4483985765124588 1.178373116952549 0.2386478901795437 1.0 0.2651170771081434 2 P43246 1 +Myosin tail [IPR002928] 0.4803206805881114 1.1646563222332946 0.2441581356489313 1.0 0.2708765081443214 3 P35580 1 +Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631] 0.4737864077669949 1.1287518466812776 0.2590025311523469 1.0 0.2861995182516408 3 P13995,Q6UB35 2 +Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630] 0.4737864077669949 1.1287518466812776 0.2590025311523469 1.0 0.2861995182516408 3 P13995,Q6UB35 2 +Intermediate filament, rod domain [IPR039008] 0.5542405329154374 1.111857580021968 0.2661993900658521 1.0 0.2937616277983342 8 P08670,P20700,P07196 3 +SH2 domain [IPR000980] 0.531374993003487 1.0644275156478396 0.2871350743928009 1.0 0.3156081425895308 10 P07948,O00459,P46108,P62993,P41240 5 +SMCs flexible hinge [IPR010935] 0.5255797294252903 1.06362814896698 0.2874971853955079 1.0 0.3158669517076638 5 Q9UQE7 1 +Elp3/MiaB/NifB [IPR006638] 0.461776920453351 1.0628072637690944 0.2878693647869421 1.0 0.3159974453251029 3 Q5VV42 1 +Radical SAM [IPR007197] 0.461776920453351 1.0628072637690944 0.2878693647869421 1.0 0.3159974453251029 3 Q5VV42 1 +Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219] 0.5206212546707358 1.0392829232130236 0.2986731744686453 1.0 0.3271369772177432 5 P05771 1 +Zinc finger, C3HC4 RING-type [IPR018957] 0.5167683848342581 1.020381999707875 0.3075473273677462 1.0 0.33641361160314 5 Q8IU81,Q5VTR2,P38398 3 +Fibronectin type II domain [IPR000562] 0.4539229188630054 1.0197495652389172 0.3078472480828043 1.0 0.3365940538003129 3 P11717 1 +Splicing factor RBM39, linker [IPR029123] 0.4196053057263013 1.0097158647607585 0.3126314393925082 1.0 0.3412266126235954 2 Q86U06 1 +SPRY-associated [IPR006574] 0.4511326860841478 1.0044725746145966 0.3151508839707779 1.0 0.3438260300188627 3 O15344,P14373 2 +Band 7 domain [IPR001107] 0.5311144565351268 0.9992608416879436 0.317668349409425 1.0 0.3463506657918379 8 P27105 1 +Glycosyltransferase 2-like [IPR001173] 0.4794927912427715 0.979577026186488 0.3272949498307986 1.0 0.3559849999467998 4 Q86SF2,O60762 2 +Sec23, C-terminal [IPR037550] 0.4073115496603005 0.9380575522389396 0.3482148344181053 1.0 0.3769304674647372 2 Q15436 1 +SLC12A transporter, C-terminal [IPR018491] 0.4047233904885106 0.9230209793559896 0.3559962723647376 1.0 0.3848524938351346 2 P55011 1 +Amino acid permease/ SLC12A domain [IPR004841] 0.4047233904885106 0.9230209793559896 0.3559962723647376 1.0 0.3848524938351346 2 P55011 1 +Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861] 0.4359223300970926 0.921454482375132 0.3568131951652911 1.0 0.3855685046543483 3 O60568,Q02809 2 +PPM-type phosphatase domain [IPR001932] 0.4355987055016225 0.9196940396102832 0.3577326682481887 1.0 0.3863946620229462 3 Q9H0C8,Q15750 2 +Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585] 0.400517631834357 0.8986316309186136 0.3688489047124847 1.0 0.3978845883879485 2 Q08170 1 +L27 domain, C-terminal [IPR014775] 0.4245954692556685 0.8600284005452512 0.3897733872778042 1.0 0.419187075407867 3 O14936,Q9NZW5 2 +L27 domain [IPR004172] 0.4245954692556685 0.8600284005452512 0.3897733872778042 1.0 0.419187075407867 3 O14936,Q9NZW5 2 +Dynamin, N-terminal [IPR045063] 0.5046783689363181 0.8468918821867507 0.3970553876494769 1.0 0.4262833133008159 7 Q9H4M9,O00429,O60313,P50570 4 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.5046783689363181 0.8468918821867507 0.3970553876494769 1.0 0.4262833133008159 7 Q9H4M9,O00429,O60313,P50570 4 +BZW1/2, W2 domain [IPR043510] 0.3879003558718851 0.82586870606448 0.4088785742526566 1.0 0.4382222450305653 2 Q9Y6E2 1 +Post-SET domain [IPR003616] 0.4993613532984973 0.8219506790055798 0.4111049678980136 1.0 0.4404191537532844 7 Q15047 1 +Band 4.1, C-terminal [IPR008379] 0.4152103559870588 0.8094850978384257 0.4182361711838178 1.0 0.4474822011722186 3 Q9Y2J2,O43491 2 +SAB domain [IPR007477] 0.4152103559870588 0.8094850978384257 0.4182361711838178 1.0 0.4474822011722186 3 Q9Y2J2,O43491 2 +Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750] 0.3840181171142001 0.80362658617163 0.4216126641065809 1.0 0.4509013654724755 2 Q8IU81 1 +Lamin tail domain [IPR001322] 0.4118296844798863 0.7913728591899641 0.4287264430553155 1.0 0.45733265568005 3 P20700 1 +CBS domain [IPR000644] 0.4935158599260915 0.7739243150220803 0.438975549679182 1.0 0.4676655364800854 6 P54619,Q6P4Q7,P51790 3 +PDZ domain [IPR001478] 0.4127208384163993 0.7719670029103552 0.4401339711156564 1.0 0.4684994127027089 18 P55196,O43464,Q00013,Q8WWI1,Q9Y4G8,Q96RT1 6 +Amidohydrolase-related [IPR006680] 0.4077669902912659 0.7696811307257927 0.4414890658134371 1.0 0.4697413524482561 3 P27708,Q9BPU6 2 +RNA recognition motif domain [IPR000504] 0.3008154700404314 0.7631256918789618 0.4453884392287006 1.0 0.4734862606293177 115 P52597,P18615,Q86U42,Q86U06,P62995,P98175,Q8WVV9,Q5T8P6,Q86V81,Q13247,O43390,P51991,Q99729,Q15233,Q9NW64,O75494,P55795,P98179,Q16629,P07910,Q8IY67,P38159,Q92879,P31942,Q14011,Q15717,Q13310,P31943,Q96E39,Q92804,Q9Y5S9,Q8WXF1,O95319,P23588,P35637,P52298,Q9UKA9,O14979,O60506,P11940,P78332 41 +Signal recognition particle SRP54, helical bundle [IPR013822] 0.3759301197023657 0.7575574383263788 0.4487159679873689 1.0 0.4766173867804506 2 P61011 1 +Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897] 0.3759301197023657 0.7575574383263788 0.4487159679873689 1.0 0.4766173867804506 2 P61011 1 +EH domain [IPR000261] 0.4313085926779477 0.7351482956399308 0.4622491840041385 1.0 0.4901570854193544 4 P42566,Q96D71 2 +Zinc finger, GATA-type [IPR000679] 0.4258487738500004 0.70805216368554 0.4789128644018732 1.0 0.5076110003477569 4 Q8WXI9 1 +Ricin B, lectin domain [IPR000772] 0.4243671121661012 0.7007281956029933 0.4834726564890115 1.0 0.5113574237843913 4 Q86SF2,Q9UBG0 2 +Peptidase M16, N-terminal [IPR011765] 0.4718758690135034 0.69466085221725 0.4872678670082182 1.0 0.5148916483041931 7 Q10713,O43847 2 +Peptidase M16, C-terminal [IPR007863] 0.4718758690135034 0.69466085221725 0.4872678670082182 1.0 0.5148916483041931 7 Q10713,O43847 2 +Beta-adaptin appendage, C-terminal subdomain [IPR015151] 0.3935275080906193 0.6943966195815683 0.4874335130898957 1.0 0.5148916483041931 3 O00203,Q10567 2 +Pentacotripeptide-repeat region of PRORP [IPR033443] 0.3552248463280519 0.6417122732071736 0.5210600188433565 1.0 0.5485536880520604 2 O75127 1 +HECT domain [IPR000569] 0.4565740326521975 0.6253572830048862 0.5317365916079075 1.0 0.559321408464834 7 Q05086,Q96J02,Q96PU5 3 +B-box, C-terminal [IPR003649] 0.4066040789899556 0.6140402964167089 0.5391886992708348 1.0 0.5666820969159132 4 O15164,O15344,Q9UPN9 3 +SH3 domain [IPR001452] 0.3560292595503466 0.613520409154463 0.5395322921495203 1.0 0.5668043540947362 28 O00459,P07948,Q96PC5,P46108,Q00013,P62993,Q03001,Q9UQB8 8 +C2 domain [IPR000008] 0.3972694399050185 0.5823796673908559 0.5603109740116783 1.0 0.5864506474103923 15 P05771,Q96PU5,Q6WKZ4 3 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.4248704663212416 0.5819731883077693 0.5605847407483462 1.0 0.5864506474103923 5 Q07157,O14936,Q9NZW5,Q00013 4 +Guanylate kinase-like domain [IPR008144] 0.4248704663212416 0.5819731883077693 0.5605847407483462 1.0 0.5864506474103923 5 Q07157,O14936,Q9NZW5,Q00013 4 +PTBP1, RNA recognition motif 2-like [IPR021790] 0.399584551029464 0.5804343544244367 0.561621743498288 1.0 0.5872891523206416 4 Q9UKA9 1 +CARP motif [IPR006599] 0.3384018117114122 0.5505383592116088 0.5819501742899023 1.0 0.6077821334501743 2 O75695 1 +C-CAP/cofactor C-like domain [IPR017901] 0.3384018117114122 0.5505383592116088 0.5819501742899023 1.0 0.6077821334501743 2 O75695 1 +Dual specificity protein phosphatase domain [IPR020422] 0.4049246229415182 0.4931823098033448 0.6218837762835323 1.0 0.6465102701338598 5 Q99956 1 +Dual specificity phosphatase, catalytic domain [IPR000340] 0.4049246229415182 0.4931823098033448 0.6218837762835323 1.0 0.6465102701338598 5 Q99956 1 +Alpha-L-fucosidase, C-terminal [IPR031919] 0.3261080556454185 0.4861037756368961 0.626893590105623 1.0 0.6514469223847599 2 Q9BTY2 1 +LEM-like domain [IPR013146] 0.3241669362665742 0.4761268546585827 0.6339840060856994 1.0 0.658540654384729 2 P42167 1 +RNA recognition motif domain, eukaryote [IPR003954] 0.3966269195929255 0.4736384886221943 0.6357577241707701 1.0 0.6601081449133642 12 P38159,Q14011,P11940,Q96E39 4 +EF-hand domain [IPR002048] 0.302607486857639 0.4187649201731147 0.6753879446399398 1.0 0.7000904131055735 44 Q9BUP0,Q66K14,P17655,Q9BRK5,Q14257,Q9NWM8,O43852,P14649,O95302,Q96AY3,P80303 11 +K Homology domain, type 1 [IPR004088] 0.3275096590933772 0.402563336661319 0.6872694857270787 1.0 0.710929115472142 22 Q92667,Q15637,O75525,Q96I24,P61978,Q06787,P51114,Q07666,Q9NQT5,Q13868,Q96AE4,Q96PU8 12 +Tyrosine-specific protein phosphatases domain [IPR000387] 0.4003753029312015 0.3982969351284337 0.6904113194048 1.0 0.7138830143431059 8 Q13614,Q99956 2 +Heat shock protein Hsp90, N-terminal [IPR020575] 0.3583684040142385 0.3932590892368324 0.6941281310877228 1.0 0.7171315488536788 4 Q12931,P08238,P07900 3 +Exportin-2, central domain [IPR013713] 0.3284789644012993 0.3746671826220403 0.7079080017713046 1.0 0.7295547753791876 3 P55060,O95373 2 +LIS1 homology motif [IPR006594] 0.3807747388592915 0.3706130550837153 0.7109257569477756 1.0 0.7320598009197987 11 Q9BZK7,Q9P260 2 +LEM domain [IPR003887] 0.398849081890499 0.370059389115915 0.7113382402544666 1.0 0.7321822415165661 6 P50402,Q86XL3 2 +Zinc finger, CCHC-type [IPR001878] 0.3897542644443582 0.3554671153543116 0.7222396765231056 1.0 0.7427900013396393 8 O95639,Q9NUD5,Q6NZY4,Q7Z6E9,Q16629 5 +FERM, C-terminal PH-like domain [IPR018980] 0.3855469435382627 0.3389115382174361 0.7346763720801928 1.0 0.753096124935471 8 Q9Y4F1,Q9Y2J2,P35241 3 +FERM, N-terminal [IPR018979] 0.3855469435382627 0.3389115382174361 0.7346763720801928 1.0 0.753096124935471 8 Q9Y4F1,Q9Y2J2,P35241 3 +Proteasomal ATPase OB C-terminal domain [IPR032501] 0.3594559585492206 0.3072136763010236 0.7586807363793073 1.0 0.7761073652707107 5 P43686,P62195,P62191,P17980 4 +Reticulon [IPR003388] 0.3318225963094803 0.2850452207787753 0.7756094971683274 1.0 0.7921253423168749 4 O95197,Q16799,O75298 3 +FERM domain [IPR000299] 0.364497035278896 0.2693211771086781 0.7876825370648279 1.0 0.8028117071678303 9 Q9Y4F1,Q9Y2J2,P35241 3 +THIF-type NAD/FAD binding fold [IPR000594] 0.3487694300518116 0.2677818309931343 0.788867256907015 1.0 0.8036907429436664 5 Q13564,Q9UBT2,A0AVT1,P22314 4 +TOG domain [IPR034085] 0.3702623906705508 0.2657783138944456 0.7904099457161711 1.0 0.8048651652317927 6 O00410,Q7Z460,Q8TEX9,Q14008,Q92616 5 +Nuclear transport factor 2, eukaryote [IPR018222] 0.3019417475728199 0.2625025572425815 0.7929340140747185 1.0 0.8065160811999789 3 Q9UBU9,Q9UN86 2 +Nuclear transport factor 2 domain [IPR002075] 0.3019417475728199 0.2625025572425815 0.7929340140747185 1.0 0.8065160811999789 3 Q9UBU9,Q9UN86 2 +FERM central domain [IPR019748] 0.3529936196386785 0.2372285554933428 0.8124794844275232 1.0 0.8233741707282579 10 Q9Y4F1,Q9Y2J2,P35241 3 +Band 4.1 domain [IPR019749] 0.3529936196386785 0.2372285554933428 0.8124794844275232 1.0 0.8233741707282579 10 Q9Y4F1,Q9Y2J2,P35241 3 +ABC transporter type 1, transmembrane domain [IPR011527] 0.3530759168175196 0.2279761188991271 0.8196648060541931 1.0 0.82964449119284 9 Q03518,P08183 2 +Importin-beta, N-terminal domain [IPR001494] 0.3295454545454603 0.208145708615338 0.835115198324438 1.0 0.8445974471294195 13 O14980,Q9UI26,Q14974,O00410,Q92973,P55060,O95373,Q9HAV4,Q8TEX9,O43592,Q96P70,Q9UIA9 12 +Septin-type guanine nucleotide-binding (G) domain [IPR030379] 0.3301702977458269 0.2039109638101298 0.8384230772036303 1.0 0.8475991708738768 5 Q15019,Q16181 2 +ABC transporter-like, ATP-binding domain [IPR003439] 0.3284254064067824 0.1837172967541507 0.8542352390227539 1.0 0.8621864371196876 12 Q03518,P33527,P08183 3 +SWAP/Surp [IPR000061] 0.3365727243278268 0.1592880990975555 0.8734418965932447 1.0 0.8801471071125463 6 Q8IWZ8,O15042,Q15459,Q8IX01,Q8IWX8 5 +Myosin, N-terminal, SH3-like [IPR004009] 0.2911672204222062 0.1453896657810839 0.8844032234827277 1.0 0.8908326491784826 4 P35580 1 +Death domain [IPR000488] 0.2656957928802642 0.1350047954443517 0.8926080828294229 1.0 0.8983714925652061 3 Q96FV9,Q12955 2 +Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 0.318084494577476 0.1109982699604721 0.9116177186271196 1.0 0.916025217669636 7 P07948 1 +Phosphoribosyltransferase domain [IPR000836] 0.2797927461139873 0.0662331467929601 0.947192207379318 1.0 0.951005380516916 5 P11172,P07741,P00492,Q06203 4 +Proteasome component (PCI) domain [IPR000717] 0.2745160102117902 0.0653507979879682 0.9478946978045713 1.0 0.9513277168308252 18 Q99627,Q9BT78,O00231 3 +U-box domain [IPR003613] 0.2385113268608464 0.0625099043352002 0.9501567748473444 1.0 0.9532143992233616 3 Q7Z6E9,Q9UNE7 2 +RecF/RecN/SMC, N-terminal [IPR003395] 0.2947786411470717 0.056876521312737 0.9546435573081896 1.0 0.95733053153463 6 Q9UQE7 1 +Exoribonuclease, phosphorolytic domain 1 [IPR001247] 0.2908895035321212 0.0491508214458068 0.9607991026619028 1.0 0.9631161422985473 6 Q96B26 1 +TGS [IPR004095] 0.2899254940071233 0.0472839552358774 0.9622869156459432 1.0 0.9642199950265096 6 Q9NYK5,Q9Y295,Q9BW92,Q9NTK5,P55039 5 +LSM domain, eukaryotic/archaea-type [IPR001163] 0.2685672354830081 0.0043073883353731 0.9965632119772884 1.0 0.9977634085392844 10 Q9UK45,P62310,Q9Y4Y9 3 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..563d18e6a882edef1d930599ea833e1f89036f88 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase alpha 1 catalytic subunit, C-terminal [IPR039137]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA C-terminal domain [IPR032423]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADD domain [IPR025766]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARIP4, DEXH-box helicase domain [IPR044573]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ASCH domain [IPR007374]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "ATRX, ADD domain [IPR041430]", "AWS domain [IPR006560]", "Abl Interactor 1, SH3 domain [IPR035725]", "Abl-interactor, homeo-domain homologous domain [IPR012849]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acetyl-coenzyme A synthetase, N-terminal domain [IPR032387]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase [IPR006862]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Alpha/beta hydrolase fold-3 [IPR013094]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apolipoprotein B100 C-terminal [IPR022176]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAAT/Acyl-CoA thioester hydrolase C-terminal [IPR014940]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BARD1, Zinc finger, RING-type [IPR039503]", "BAT2, N-terminal [IPR009738]", "BCAS3 domain [IPR022175]", "BCL-6 corepressor, PCGF1 binding domain [IPR032365]", "BCL-6 corepressor, non-ankyrin-repeat domain [IPR031628]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BR140-related, PWWD domain [IPR035502]", "BRCA1, serine-rich domain [IPR025994]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BRPF2, PHD domain [IPR042009]", "BRPF2, ePHD domain [IPR042004]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-trefoil DNA-binding domain [IPR015350]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin/lipoyl attachment [IPR000089]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Bud22 domain [IPR015158]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBF1-interacting co-repressor CIR, N-terminal domain [IPR019339]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCDC93, coiled-coil domain [IPR019159]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-C, middle DNMT3B-binding domain [IPR028931]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COG complex component, COG2, C-terminal [IPR024603]", "COMM domain [IPR017920]", "COMMD1 N-terminal domain [IPR033776]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COQ9 [IPR013718]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRAL/TRIO, N-terminal domain [IPR011074]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centrosomal CEP44 domain [IPR029157]", "Chaperone DnaJ, C-terminal [IPR002939]", "Checkpoint kinase 1, catalytic domain [IPR034670]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain [IPR041715]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Classical Protein Kinase C alpha, catalytic domain [IPR034663]", "Classical protein kinase C beta, catalytic domain [IPR034664]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Conserved oligomeric Golgi complex, subunit 2, N-terminal [IPR024602]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-glucuronyl C5-epimerase, C-terminal [IPR010598]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEK, C-terminal [IPR014876]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIRP domain [IPR033471]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein Rad51-like, C-terminal [IPR013632]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA recombination and repair protein RecA-like, ATP-binding domain [IPR020588]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase 3-like, TOPRIM domain [IPR034144]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IA, DNA-binding domain [IPR003602]", "DNA topoisomerase, type IA, central [IPR013497]", "DNA topoisomerase, type IA, domain 2 [IPR003601]", "DNA topoisomerase, type IA, zn finger [IPR013498]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dehydrogenase, E1 component [IPR001017]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF1977, DnaJ-like [IPR015399]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3528, homeobox protein, eukaryotic [IPR021918]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF3699 [IPR022168]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4195 [IPR025243]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4477 [IPR027951]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF4757 [IPR031865]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drought induced 19 protein type, zinc-binding domain [IPR008598]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EXOG, C-terminal [IPR041003]", "EXPERA domain [IPR033118]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enhancer of polycomb-like, N-terminal [IPR019542]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst complex component Sec3, C-terminal [IPR019160]", "Exocyst complex component Sec3, PIP2-binding N-terminal domain [IPR028258]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM192A/Fyv6, N-terminal [IPR019331]", "FAM3C (ILEI) domain [IPR039475]", "FAM69, protein-kinase domain [IPR022049]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FLYWCH-type zinc finger-containing protein, N-terminal [IPR029279]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferritin-like diiron domain [IPR009040]", "Ferritin/DPS protein domain [IPR008331]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Ferrodoxin-fold anticodon-binding domain [IPR005121]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Follistatin-like, N-terminal [IPR003645]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCF, C-terminal [IPR022783]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPI ethanolamine phosphate transferase 2, C-terminal [IPR045687]", "GPI ethanolamine phosphate transferase 2, N-terminal [IPR037674]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "Gid-type RING finger domain [IPR044063]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucose-methanol-choline oxidoreductase, C-terminal [IPR007867]", "Glucose-methanol-choline oxidoreductase, N-terminal [IPR000172]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyl transferase, family 28, C-terminal [IPR007235]", "Glycosyltransferase 2-like [IPR001173]", "Glycosyltransferase subfamily 4-like, N-terminal domain [IPR028098]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Groucho/TLE, N-terminal Q-rich domain [IPR005617]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Heavy metal-associated domain, HMA [IPR006121]", "Heavy metal-associated domain, copper ion-binding [IPR006122]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "HhH-GPD domain [IPR003265]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histidyl-anticodon-binding [IPR033656]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homeobox domain, metazoa [IPR020479]", "Homocysteine-binding domain [IPR003726]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "Hpc2-related domain [IPR014840]", "HuR, RNA recognition motif 2 [IPR034996]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I/LWEQ domain [IPR002558]", "IF2a, S1-like domain [IPR044126]", "IFT81, calponin homology domain [IPR041146]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Inhibitor of growth protein, N-terminal histone-binding [IPR024610]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrator complex subunit 5, C-terminal [IPR029444]", "Integrator complex subunit 5, N-terminal [IPR029445]", "Integrin alpha-2 [IPR013649]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KAP family P-loop domain [IPR011646]", "KASH domain [IPR012315]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KMT2B, ePHD domain [IPR041959]", "KOW [IPR005824]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore assembly subunit CENP-C, N-terminal domain [IPR028052]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIN-9, C-terminal [IPR045831]", "LIS1 homology motif [IPR006594]", "LKB1 serine/threonine kinase interacting protein 1, N-terminal [IPR031782]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "LYRM2, LYR domain [IPR045293]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipid desaturase domain [IPR019547]", "Lipid transport, open beta-sheet [IPR009454]", "Little elongation complex subunit 2 , C-terminal [IPR019535]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lunapark domain [IPR019273]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "MABP domain [IPR023341]", "MAGE homology domain [IPR002190]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MYST, zinc finger domain [IPR040706]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Mediator complex, subunit Med12 [IPR019035]", "Mediator complex, subunit Med12, LCEWAV-domain [IPR021990]", "Mediator complex, subunit Med12, catenin-binding [IPR021989]", "Mediator complex, subunit Med25, NR box [IPR021406]", "Mediator complex, subunit Med25, PTOV domain [IPR021394]", "Mediator complex, subunit Med25, synapsin 1 [IPR021397]", "Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain [IPR021419]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "MgsA AAA+ ATPase C-terminal [IPR021886]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Mif2/CENP-C cupin domain [IPR025974]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondria fission protein Fis1, cytosolic domain [IPR033745]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdenum cofactor synthesis C-terminal [IPR010505]", "Molybdopterin cofactor biosynthesis C (MoaC) domain [IPR002820]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Myb domain [IPR017930]", "Myc-type, basic helix-loop-helix (bHLH) domain [IPR011598]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myotubularin-like phosphatase domain [IPR010569]", "Myotubularin-related 12-like C-terminal domain [IPR022587]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-CoR, GPS2-interacting domain [IPR031557]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-acetyltransferase ESCO, acetyl-transferase domain [IPR028009]", "N-acetyltransferase ESCO, zinc-finger [IPR028005]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase intermediate-associated protein 30 [IPR013857]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NCBP2, RNA recognition motif [IPR034148]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, C-terminal [IPR001075]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NP60, PWWP domain [IPR035501]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nischarin, PX domain [IPR037904]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear hormone receptor, ligand-binding domain [IPR000536]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear protein 96 [IPR021967]", "Nuclear speckle splicing regulatory protein 1, N-terminal [IPR018612]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar 27S pre-rRNA processing, Urb2/Npa2, C-terminal [IPR018849]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PB1 domain [IPR000270]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K p85 subunit, C-terminal SH2 domain [IPR035020]", "PI3K p85 subunit, N-terminal SH2 domain [IPR035022]", "PI3K regulatory subunit p85-related , inter-SH2 domain [IPR032498]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PINIT domain [IPR023321]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLD-like domain [IPR032803]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKAA1, UBA-like autoinhibitory domain [IPR028797]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palmitoyltransferase, DHHC domain [IPR001594]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Patatin-like phospholipase domain [IPR002641]", "Patatin-like phospholipase domain containing protein 8-like [IPR045217]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 3-kinase regulatory subunit beta, SH3 domain [IPR035586]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Plus-3 domain [IPR004343]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Pop1, N-terminal [IPR009723]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein OS9-like domain [IPR012913]", "Protein RED, C-terminal [IPR012492]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein furry, C-terminal [IPR045842]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAD51 interacting motif [IPR031419]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM40, RNA recognition motif 1 [IPR034147]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM8, RNA recognition motif [IPR033744]", "RBP-J/Cbf11/Cbf12, DNA binding [IPR015351]", "RBP-Jkappa, IPT domain [IPR038007]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING finger and SPRY domain-containing protein 1, SPRY domain [IPR035774]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 2-O ribose methyltransferase, substrate binding [IPR013123]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II elongation factor ELL, N-terminal [IPR019464]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RQC domain [IPR018982]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rad18, zinc finger UBZ4-type [IPR006642]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad51/DMC1/RadA [IPR033925]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap1 Myb domain [IPR015010]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rhodanese-like domain [IPR001763]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal RNA-processing protein 7, C-terminal domain [IPR024326]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ricin B, lectin domain [IPR000772]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rrp7, RRM-like N-terminal domain [IPR040447]", "Rrp7A, RNA recognition motif [IPR034890]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SCAF8, RNA recognition motif [IPR034370]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD2/Set2, SET domain [IPR044437]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGF29 tudor-like domain [IPR010750]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMYD3, SET domain [IPR044420]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX2, PX domain [IPR037918]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPOP, C-terminal BACK domain [IPR034089]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAR protein, homodimerisation region [IPR032377]", "STARD11, START domain [IPR041952]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Scaffold protein Nfu/NifU, N-terminal [IPR014824]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine proteases, trypsin domain [IPR001254]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set2 Rpb1 interacting domain [IPR013257]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein LSm5 [IPR033871]", "Sm-like protein Lsm3 [IPR034105]", "Sm-like protein Lsm4 [IPR034101]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromal interaction molecule 1, SAM domain [IPR037609]", "Stromal interaction molecule, Orai1-activating region [IPR032393]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfatase-modifying factor enzyme [IPR005532]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA element modulatory factor 1, TATA binding [IPR022091]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG, PB1 domain [IPR034857]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TGS [IPR004095]", "THAP-type zinc finger [IPR006612]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRC8 N-terminal domain [IPR025754]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRIM27, PRY/SPRY domain [IPR035791]", "TRIM4, PRY/SPRY domain [IPR035829]", "TROVE domain [IPR008858]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Target SNARE coiled-coil homology domain [IPR000727]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere repeat-binding factor, dimerisation domain [IPR013867]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Telomeric repeat-binding factor 2, Rap1-binding domain [IPR031902]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine synthase, N-terminal [IPR029144]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor 20, ePHD domain [IPR041972]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Lyn, SH2 domain [IPR035852]", "Tyrosine-protein kinase Lyn, SH3 domain [IPR035748]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC2, UBA domain [IPR041928]", "UBX domain [IPR001012]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UMA domain [IPR023340]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "UVR domain [IPR001943]", "Ubinuclein middle domain [IPR026947]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VIP36, lectin domain [IPR035664]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vitellinogen, open beta-sheet [IPR015255]", "Vitellogenin, N-terminal [IPR001747]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WRNIP1, ubiquitin-binding domain [IPR040539]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C2HC5-type [IPR009349]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FCS-type [IPR012313]", "Zinc finger, FLYWCH-type [IPR007588]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc finger, nuclear hormone receptor-type [IPR001628]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cDENN domain [IPR001194]", "dDENN domain [IPR005112]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA splicing factor Cwf21 domain [IPR013170]", "p21 activated kinase binding domain [IPR033923]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNase Z endonuclease [IPR027794]", "uDENN domain [IPR005113]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTN1", "ACTN4", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "APLP2", "APMAP", "APOB", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL2", "ARL3", "ARL8A", "ARL8B", "ARMC10", "ARMCX3", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATP7A", "ATP7B", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAP18", "BARD1", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS3", "BCKDHA", "BCKDHB", "BCOR", "BCS1L", "BIRC6", "BLM", "BLVRA", "BMI1", "BMS1", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "C1orf35", "C2CD5", "C3orf58", "CACYBP", "CAD", "CALU", "CAMK2G", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASK", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC93", "CCNB1", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC34", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPV", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHORDC1", "CHP1", "CHRAC1", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLIC1", "CLPB", "CLPX", "CLTC", "CLUH", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNPY2", "COA3", "COG2", "COIL", "COL4A3BP", "COLEC12", "COMMD1", "COMMD10", "COMMD5", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC25", "CWF19L1", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCTN1", "DCUN1D5", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "EARS2", "ECE1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMC8", "EMD", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESCO2", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM192A", "FAM208A", "FAM208B", "FAM3C", "FAM49B", "FAM8A1", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FBXO22", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDE1", "GDPD1", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGB1", "GORASP2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPI", "GPR89B", "GPS1", "GPT2", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F2", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HELLS", "HELZ", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA4", "HSPA4L", "HSPB1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "IARS", "IARS2", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS11", "INTS14", "INTS3", "INTS5", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "IVD", "IWS1", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1147", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LETMD1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LRRC8C", "LSM12", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "M6PR", "MACF1", "MAEA", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBD3", "MBNL1", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED25", "MEPCE", "METTL7B", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD8", "MGME1", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPHOSPH8", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRM3", "MRPL11", "MRPL12", "MRPL15", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCBP1", "NCBP2", "NCEH1", "NCKIPSD", "NCL", "NCLN", "NCOR1", "NCSTN", "NDUFA10", "NDUFA2", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFE", "NENF", "NEPRO", "NES", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NTHL1", "NTPCR", "NUB1", "NUBP1", "NUCB1", "NUCB2", "NUDC", "NUDT1", "NUDT12", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NVL", "NXF1", "NXN", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAXBP1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDZD8", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF3", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP4R1", "PPP5C", "PPP6C", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2B", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPMT1", "PTPN1", "PTPN9", "PUF60", "PUM3", "PUS1", "PWP2", "PWWP2A", "PYCR1", "PYCR2", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RAC1", "RACGAP1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAI1", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOX1", "RIPK1", "RMND1", "RNASEH2A", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPEP", "RNPS1", "RP2", "RPA1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRP12", "RRP7A", "RSF1", "RSL24D1", "RSPRY1", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SC5D", "SCAF11", "SCAF8", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A2", "SLC27A4", "SLC2A1", "SLC37A4", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMU1", "SMYD3", "SNAP23", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPC25", "SPECC1L", "SPEN", "SPNS1", "SPOP", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK11IP", "STK26", "STOM", "STOML2", "STRBP", "STRN", "STRN4", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THNSL1", "THOC1", "THOC2", "THOC3", "THOP1", "THYN1", "TIAL1", "TIMELESS", "TIMM10", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TKT", "TLCD1", "TLE3", "TLN1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED8", "TMED9", "TMEM201", "TMEM205", "TMEM97", "TMF1", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOX4", "TP53", "TP53BP1", "TPBG", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMT1L", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TST", "TTC4", "TTF1", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBFD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCRC1", "UQCRC2", "URB1", "URB2", "UROD", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS16", "VPS29", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WASHC4", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WRNIP1", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YBX1", "YBX3", "YES1", "YIPF4", "YKT6", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZCCHC17", "ZCCHC3", "ZCCHC8", "ZDHHC20", "ZEB2", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF148", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF644", "ZPR1", "ZRANB2", "ZYX"], "leading_proteins": ["ABCB1", "ABCC1", "ABI1", "ACTN1", "ADD3", "AFDN", "AKAP1", "AKAP8L", "AKT2", "ALYREF", "ANK3", "ANKLE2", "AP1B1", "AP3B1", "AP3M1", "APRT", "ATAD3A", "ATP13A1", "ATP7B", "BAG3", "BAG4", "BAG6", "BAIAP2", "BRCA1", "BZW2", "CACYBP", "CAD", "CALU", "CAPN2", "CASK", "CBX1", "CDKAL1", "CELF1", "CELF2", "CHERP", "CHTOP", "CIRBP", "CKAP5", "CLASP1", "CLCN3", "CNNM4", "COL4A3BP", "COLEC12", "COPG2", "COPS4", "COPS8", "CPSF4", "CPT2", "CRK", "CSE1L", "CSK", "CYB5D2", "CYFIP2", "DHCR24", "DNAJA2", "DNM1L", "DNM2", "DPM1", "DPYSL5", "DRG1", "DRG2", "DST", "DUSP9", "EEF1D", "EFHD1", "EHD1", "EIF4B", "ELAVL1", "EMD", "EPB41L2", "EPB41L3", "EPHA7", "EPS15", "ERAP1", "ERBIN", "ERMP1", "EXOC2", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "FAF2", "FAM49B", "FARP1", "FHOD1", "FKBP10", "FKBP14", "FKBP9", "FMR1", "FOXRED1", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "G3BP2", "GALNT7", "GAPVD1", "GATAD2B", "GCN1", "GINS3", "GRB2", "HADH", "HDGFL2", "HELZ", "HLA-C", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPLL", "HNRNPR", "HPRT1", "HSP90AA1", "HSP90AB1", "HTRA2", "IGF2R", "ILKAP", "IPO11", "IPO4", "IPO5", "IPO7", "IPO9", "IRF2BP1", "ITCH", "KDELC1", "KHDRBS1", "KHDRBS3", "KIAA1468", "KPNB1", "L3MBTL3", "LMAN1", "LMNB1", "LMO7", "LNPEP", "LSM3", "LSM5", "LSM7", "LYN", "M6PR", "MCM3", "MCM4", "MCM6", "MCM7", "ME1", "MFN1", "MIA2", "MID1", "MOV10", "MPP1", "MPP6", "MPRIP", "MRC2", "MRPL39", "MSH2", "MTHFD1L", "MTHFD2", "MTMR2", "MTX1", "MYH10", "MYL6B", "NAA40", "NAE1", "NCBP2", "NEDD4L", "NEFL", "NELFE", "NENF", "NONO", "NPEPPS", "NRDC", "NUCB2", "NXF1", "OCLN", "OLA1", "OPA1", "OSBPL6", "P3H1", "PABPC1", "PABPC4", "PABPN1", "PCYOX1", "PIK3R2", "PLOD1", "PLOD3", "PMPCA", "PNPLA6", "POLR2C", "PPAT", "PREP", "PREPL", "PRKAG1", "PRKCB", "PRPF40A", "PSMC1", "PSMC3", "PSMC4", "PSMC5", "PSMD11", "PSPC1", "PTBP2", "PTCD1", "QKI", "RAB11FIP1", "RAPGEF2", "RAVER1", "RBBP6", "RBM10", "RBM22", "RBM23", "RBM26", "RBM3", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RCN2", "RDX", "REPS1", "RNF20", "RP2", "RPS6KA3", "RTN1", "RTN2", "RTN3", "SAMHD1", "SDF4", "SEC23A", "SEC31A", "SEPT2", "SEPT7", "SETDB1", "SF1", "SF3A1", "SKIV2L2", "SLC12A2", "SMC3", "SNRPA1", "SPOP", "SPTAN1", "SRP54", "SRSF10", "SRSF4", "SRSF6", "SRSF7", "STAG1", "STAU1", "STOM", "STUB1", "STX10", "STX5", "STX7", "SUGP1", "SUGP2", "SUMO2", "SYNCRIP", "TAB1", "TAF15", "TAP1", "TARS2", "TBC1D9B", "TBCB", "TBL1XR1", "TCERG1", "THOC1", "THOP1", "TIMM50", "TJP1", "TLCD1", "TMPO", "TNPO1", "TPBG", "TRA2B", "TRAP1", "TRIM24", "TRIM27", "TRIM33", "TUBB", "TUBB6", "U2SURP", "UBA1", "UBA2", "UBA6", "UBE3A", "UBR5", "UBXN4", "UMPS", "UNC119B", "USP5", "UTRN", "VIM", "XPO1", "XPO5", "XPO7", "XPOT", "YBX3", "YME1L1", "ZCCHC3", "ZCCHC8"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..07a7a8c0db7b245e9359961ae69132dcd4a19d33 --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..90396d399a62d904ea53797f4bc5dae388bb843f --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5baae13bae5edb67eeffd3a259d9f31f9ec2f5ec0ecd4314587d87e382a1748a +size 146029 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..0a5c8ab33d866c6e9d9d05e8b78db0809831fbb1 --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fe854297169e968cacb4d4ec59ef8638e3163ae47716f5b12784ee0bb8d91e01 +size 927065 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ed8b8046fbd5a81fbdd04e0498e70a5b9aadab99 --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proteasome B-type subunit [IPR023333] 4 7 2.5052883345864547 0.0122351606009831 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 1.0 1.0 0.0031504918831051 9.327097249989188e-07 9.088718771147158e-07 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 3 5 2.409587730095485 0.0159705558708798 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0340178825746634 0.0378187125466048 0.002465796513642 0.0007187465088185 0.0003209969829564 +Thiolase [IPR002155] 0 5 2.3721247267248606 0.0176861192402888 2.5606796116504853 4.844660194174757 -0.5308970493980486 0.3952147264399792 1.6528021290928414 0.3622283127413132 1.0786004395841309 0.2880439628871515 0.0213958237580913 0.0238038053541035 0.0471521402185075 0.1154193350298319 0.2191219719972187 +Proteasome, subunit alpha/beta [IPR001353] 4 14 2.1234964709534787 0.0337122709076866 5.075242718446602 13.970873786407768 1.2284854682369022 0.3020132543529001 2.3027355385508845 0.1681602725795027 1.1101966392985694 0.3179790146746512 1.0 1.0 0.0100519320580488 2.812625820330817e-05 6.478838546237441e-05 +Mitochondrial carrier protein [IPR002067] 3 15 1.987352841554723 0.0468833097375558 5.686893203883495 11.07766990291262 0.8032246115450145 0.31892620527414 3.2338505495684404 1.5403272908315857 1.3918146051602212 0.3274613788058813 1.0 1.0 0.0155240337321844 0.0011993766429203 0.0140088487662649 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e60cbfd09a288ed828ba523cfae6c001d7900c46 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 2385, + "title": "Average number of proteins per term", + "value": 1.288888888888889 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5c34b27200f57e3c488b1517b2775152ec377a4e --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..59c46b51607d5b98a151541c7483813606601ee0 --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,113 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.9951472015528956 3.969529768874733 7.201460975703178e-05 0.1578195941801302 0.0005335819933712 2 O60830 1 +Mpv17/PMP22 [IPR007248] 0.986412164348108 3.931748984803448 8.433009410224734e-05 0.1821985969811685 0.0005633817211032 2 Q567V2 1 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.9825299255904248 3.914899345165402 9.044192994633882e-05 0.1940340297121487 0.0005827595023255 2 Q5VW38 1 +Haem oxygenase [IPR002051] 0.9757360077644788 3.885325579591973 0.0001021928410975 0.216310498116057 0.0006062933483028 2 P30519 1 +Haem oxygenase-like [IPR016053] 0.9757360077644788 3.885325579591973 0.0001021928410975 0.216310498116057 0.0006062933483028 2 P30519 1 +Prenylcysteine oxidase [IPR017046] 0.963765771594954 3.832947607832933 0.0001266169276041 0.2606622988105034 0.0006724186311762 2 Q9UHG3 1 +ER lumen protein retaining receptor [IPR000133] 0.9456486573924304 3.7530022648673502 0.0001747292757745 0.3408246760199487 0.0007968055883791 2 O43731 1 +Acyltransferase ChoActase/COT/CPT [IPR000542] 0.9252669039145954 3.6620764830298937 0.0002501791379947 0.4494028677343049 0.0010113173629109 2 P23786 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.9197670656745404 3.637358317065268 0.0002754486203226 0.4816141622016037 0.0010682031861294 2 Q9Y487 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.9197670656745404 3.637358317065268 0.0002754486203226 0.4816141622016037 0.0010682031861294 2 Q9Y487 1 +CD36 family [IPR002159] 0.9103849886768076 3.595010056385425 0.000324379046674 0.538728988102103 0.0011616276671435 2 Q8WTV0 1 +Palmitoyl protein thioesterase [IPR002472] 0.9100614687803346 3.593545651328808 0.0003262084637918 0.5407378550302512 0.0011664275654325 2 Q9UMR5 1 +Histidine phosphatase superfamily, clade-2 [IPR000560] 0.969407898755242 3.5693629683251276 0.0003578503385532 0.5741319837393885 0.0012361697927146 3 Q9NPH0 1 +E3 ubiquitin-protein ligase, SMURF1 type [IPR024928] 0.8964736331284431 3.5317900215760902 0.00041275696667 0.6264220466125837 0.0013597035435195 2 Q96PU5 1 +Aminopeptidase N-type [IPR034016] 0.9530744336569544 3.499437009610122 0.0004662417507104 0.6711803593777144 0.0014846282716212 3 Q9UIQ6,P55786 2 +Stomatin/HflK/HflC family [IPR001972] 0.8683274021352319 3.402280883299861 0.0006682591795297 0.7969556631510001 0.0019156227682432 2 P27105 1 +Peptidase S9A, prolyl oligopeptidase [IPR002470] 0.8634746036881353 3.3797309204166193 0.0007255682703113 0.8229119866330914 0.0020259681996545 2 Q4J6C6 1 +Vacuolar protein sorting-associated protein 33 [IPR027121] 0.861533484309285 3.3706924719519384 0.0007497950793633 0.8328614240142609 0.0020796260132261 2 Q9H267 1 +HnRNP R/Q splicing factor [IPR006535] 0.8372694920737631 3.256809565220669 0.0011267199651086 0.9320336215821186 0.0027904746799418 2 O43390 1 +Molecular chaperone regulator BAG [IPR039773] 0.8755993169553755 3.1589055806708637 0.0015836278745207 0.9771760826320458 0.0036275231387552 3 O95429 1 +Purine 5'-nucleotidase [IPR016695] 0.8049175024264037 3.1023003131370506 0.0019202304860426 0.9897875981925872 0.0041776536153087 2 P49902 1 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.8540453074433454 3.061445876609308 0.0022027081070314 0.9948008143112445 0.0046614541572937 3 P28074,Q99436 2 +Peptidase M3A/M3B [IPR045090] 0.8436219528831881 3.013871729591933 0.0025793683503834 0.9978871997016582 0.0052941424403308 3 P52888 1 +Tropomodulin [IPR004934] 0.7719184729860902 2.9414435221679227 0.0032668640948898 0.9995919926995716 0.0063191166798964 2 P28289 1 +Paraneoplastic encephalomyelitis antigen [IPR002343] 0.771594953089618 2.939849778868259 0.0032837140652857 0.9996081160183128 0.0063362929172382 2 O95319 1 +Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515] 0.7699773536072492 2.9318761278047507 0.0033692110371918 0.9996806221166544 0.0064646567366875 2 P11940 1 +Fragile X mental retardation syndrome-related protein [IPR040148] 0.7670656745389843 2.917502792878253 0.0035284648883497 0.999781837525592 0.006694820014888 2 P51114 1 +Transcriptional repressor p66 [IPR040386] 0.7664186347460454 2.914305086133921 0.0035648133957446 0.999800015405958 0.0067423314423878 2 Q8WXI9 1 +Prefoldin beta-like [IPR002777] 0.7615658362989397 2.890280052001997 0.0038489876845448 0.9998987125079062 0.0071216723255543 2 O60925 1 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.7602717567130353 2.88386075744301 0.0039283240805645 0.999916235695871 0.0072459806126422 2 Q9NVI7 1 +TAF15/EWS/TLS family [IPR034870] 0.7593011970236282 2.8790427906645153 0.0039888420801945 0.9999275354202024 0.0073236246045142 2 Q92804 1 +Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699] 0.7544483985765187 2.854907894014308 0.0043049311743257 0.9999660093274478 0.0077840526664683 2 Q9NQT5 1 +HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380] 0.8051779935274948 2.8358420995884694 0.004570503661841 0.9999820089857112 0.0081348143533514 3 P49902,Q5TFE4 2 +Ancient conserved domain protein family [IPR045095] 0.7473309608540951 2.8193735599714325 0.0048117483752798 0.999989907506454 0.0085007554629944 2 Q6P4Q7 1 +Sulfotransferase [IPR005331] 0.7460368812682109 2.8128952523753266 0.0049097641911171 0.9999920204471568 0.0086419096648076 2 Q8NCH0 1 +Tubulin [IPR000217] 0.7987055016181124 2.8054642136733534 0.0050244160294674 0.999993937800208 0.0087468848396203 3 P07437,Q9BUF5 2 +Beta tubulin [IPR002453] 0.7987055016181124 2.8054642136733534 0.0050244160294674 0.999993937800208 0.0087468848396203 3 P07437,Q9BUF5 2 +ADP-ribosylation factor-like protein 2/3 [IPR044612] 0.7318020058233625 2.7412753205497 0.0061201201281597 0.9999995621264702 0.0102719820588747 2 P36405 1 +Peptidase, FtsH [IPR005936] 0.7275962471692083 2.7199882647370353 0.0065284233166513 0.999999835661354 0.0108352746069683 2 Q96TA2 1 +Anoctamin [IPR007632] 0.7169200905855782 2.6656900931610763 0.0076830481749956 0.99999998973807 0.0123373901021034 2 Q4KMQ2 1 +Dynamin [IPR022812] 0.7582524271844526 2.612888379809722 0.0089780618923085 0.9999999995443878 0.0140780260441524 3 O00429,P50570 2 +A-kinase anchoring protein 95 (AKAP95) [IPR007071] 0.757740625559612 2.6104215762560097 0.0090430703737289 0.999999999610374 0.0141613413272118 3 Q9ULX6 1 +Tricarboxylate/iron carrier [IPR004686] 0.7501618122977343 2.5738028937075095 0.0100587559012603 0.9999999999662352 0.0154476064549298 3 Q6P4A7,Q96NB2 2 +Malic oxidoreductase [IPR001891] 0.6988029763830537 2.572679827983734 0.0100914515129697 0.999999999968793 0.0154778854395066 2 P48163 1 +Clathrin adaptor, mu subunit [IPR001392] 0.7445437672568705 2.5465489321432297 0.01087939576431 0.9999999999953284 0.0164431932179211 3 Q9Y2T2 1 +Proteasome B-type subunit [IPR023333] 0.8649711853928109 2.5052883345864547 0.0122351606009831 0.9999999999998228 0.0180462943929158 7 P28070,P49721,P28074,Q99436 4 +P-type ATPase, subfamily IB [IPR027256] 0.6677450663215848 2.4106538106802744 0.0159239553364973 1.0 0.0222097271798516 2 P35670 1 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.8099090261299893 2.4095877300954855 0.0159705558708798 1.0 0.0222617041215945 5 Q9UIQ6,Q9NZ08,P55786 3 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.7107340559137065 2.3805519203215457 0.0172867247711487 1.0 0.0238179310105082 3 Q9HB40 1 +E3 ubiquitin ligase Bre1 [IPR013956] 0.6573924296344242 2.355912309091996 0.0184772789617619 1.0 0.0250958487037598 2 Q5VTR2 1 +Tropomyosin [IPR000533] 0.6987914518321097 2.321098290798057 0.0202815396210844 1.0 0.0272361891870982 3 P67936 1 +Prohibitin [IPR000163] 0.6489809123261101 2.3111631903844656 0.0208238427130484 1.0 0.0278390498153703 2 P35232 1 +KH domain-containing BBP-like [IPR045071] 0.7400453221107143 2.2852860689682317 0.0222960592581118 1.0 0.0294441314122905 4 O75525,Q07666,Q96PU8 3 +Porin, eukaryotic type [IPR001925] 0.6883730120057034 2.2688814730548303 0.0232755346723094 1.0 0.0304844317372092 3 P21796 1 +Ribosomal protein S6 kinase II [IPR016239] 0.6334519572953776 2.2279082188406405 0.0258866360041436 1.0 0.0332112032651331 2 P51812 1 +Ezrin/radixin/moesin [IPR011174] 0.6786067914353339 2.2196363816853384 0.0264434605453112 1.0 0.0338527393454467 3 P35241 1 +G-protein alpha subunit, group I [IPR001408] 0.6647707767742668 2.14937809702565 0.0316044402581554 1.0 0.0391566701380263 3 P04899 1 +DNA2/NAM7-like helicase [IPR045055] 0.7096739982393361 2.1406705809515745 0.0323006125425755 1.0 0.0399155237896594 4 Q9HCE1,P42694 2 +Proteasome, subunit alpha/beta [IPR001353] 0.6781546477395926 2.1234964709534787 0.0337122709076866 1.0 0.0412962332382294 14 P28070,P49721,P28074,Q99436 4 +Profilin1/2/3, vertebrate [IPR005454] 0.6014234875444899 2.053573225346738 0.0400170157774997 1.0 0.0475065120106206 2 P07737 1 +Profilin [IPR005455] 0.6014234875444899 2.053573225346738 0.0400170157774997 1.0 0.0475065120106206 2 P07737 1 +Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019] 0.6853653871784087 2.0231715198130136 0.0430554668923108 1.0 0.0504357998713956 4 P04899,Q14344 2 +Prenylated rab acceptor PRA1 [IPR004895] 0.6385839183356576 2.0148354028584885 0.0439218982259022 1.0 0.051249377333061 3 Q9UI14 1 +Ribosomal protein L14P [IPR000218] 0.5926884503397025 2.0054199122222345 0.0449181747272375 1.0 0.0522378690057968 2 P62829 1 +Mitochondrial carrier protein [IPR002067] 0.6426131155294282 1.987352841554723 0.0468833097375558 1.0 0.0541485199632303 15 Q8TBP6,Q96H78,Q86VD7 3 +Syntaxin [IPR045242] 0.7394956076185002 1.9527255048625256 0.0508521298434991 1.0 0.0581689830583911 7 Q13190,O15400,O60499 3 +Sec1-like protein [IPR001619] 0.6846971734352857 1.8361689721444416 0.0663326700594078 1.0 0.0725703752714163 5 Q9H267,Q96AX1 2 +Coatomer gamma subunit [IPR017106] 0.5587188612099732 1.81575292645456 0.0694082812248217 1.0 0.0754162873445102 2 Q9UBF2 1 +ATP-dependent RNA helicase Ski2-like [IPR016438] 0.5583953413134997 1.8139286896447528 0.0696887051223962 1.0 0.0756528199365011 2 P42285 1 +Tyrosine-tRNA ligase [IPR002307] 0.5509543836946065 1.7718814471053743 0.0764142387590904 1.0 0.0816157453830859 2 Q9Y2Z4 1 +Structural maintenance of chromosomes protein [IPR024704] 0.6318941753774517 1.7594097610885386 0.0785079351824049 1.0 0.0835899220580517 4 Q9UQE7,Q9NTJ3 2 +TB2/DP1/HVA22-related protein [IPR004345] 0.6316614606193445 1.758246620258269 0.07870555591476 1.0 0.0837629410337807 4 Q9BRK0 1 +Erlin1/2 [IPR033294] 0.5396311873180268 1.707573571690559 0.0877154956651291 1.0 0.0917952861611816 2 O94905 1 +Mitofusin family [IPR027094] 0.5393076674215566 1.705730618431815 0.0880582461822179 1.0 0.0921135601511358 2 Q8IWA4 1 +Eukaryotic porin/Tom40 [IPR027246] 0.6125112034333609 1.66211017956282 0.0964906848910502 1.0 0.1008017010359855 4 P21796 1 +Mini-chromosome maintenance protein [IPR031327] 0.6817967649668069 1.6497865188299148 0.0989866070294378 1.0 0.1033638606677798 6 P33993,Q14566,P33991,P25205 4 +CPSF6/7 family [IPR034772] 0.5160142348754555 1.5722684876224626 0.115888297986229 1.0 0.1204329371229438 2 Q16630 1 +Developmentally regulated GTP-binding protein [IPR045001] 0.5105143966353963 1.5405482182551735 0.1234267788424348 1.0 0.1279937964005582 2 P55039 1 +Bax inhibitor 1-related [IPR006214] 0.495956001294084 1.4562417864305006 0.1453257917914054 1.0 0.1503044290643981 2 P55061 1 +Cohesin subunit Scc3/SA [IPR039662] 0.4671627305079266 1.2883219896003315 0.1976339016041803 1.0 0.2035219582581909 2 Q8WVM7 1 +Vinculin/alpha-catenin [IPR006077] 0.4571336137172429 1.2295829430022769 0.2188533205939538 1.0 0.2250820050093056 2 P35221 1 +Chaperone DnaJ [IPR012724] 0.4532513749595626 1.2068266188935255 0.2274989224526877 1.0 0.2337720508615511 2 O60884 1 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.4532513749595626 1.2068266188935255 0.2274989224526877 1.0 0.2337720508615511 2 O60884 1 +P-type ATPase [IPR001757] 0.5614042126547141 1.180271272883491 0.2378923398345271 1.0 0.2443467831633709 9 Q9HD20 1 +Sulfurtransferase TST/MPST-like [IPR045078] 0.4451633775477332 1.1594018883013135 0.2462924074425727 1.0 0.2528658595568386 2 P25325 1 +Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672] 0.4737864077669949 1.1287518466812776 0.2590025311523469 1.0 0.2655722428195819 3 P13995,Q6UB35 2 +Cell-cycle alteration and expression-elevated protein in tumour [IPR032337] 0.4637540453074486 1.073656831733914 0.2829765158141866 1.0 0.2897805883283963 3 Q96P16,Q5VT52 2 +THRAP3/BCLAF1 family [IPR029199] 0.4199288256227734 1.011605938852358 0.3117265051955478 1.0 0.318674545602821 2 Q9NYF8 1 +Splicing factor, RBM39-like [IPR006509] 0.4196053057263013 1.0097158647607585 0.3126314393925082 1.0 0.319462717631162 2 Q86U06 1 +Ribosomal protein S11 [IPR001971] 0.4118408282109305 0.964416631801344 0.3348370870705885 1.0 0.3417143571516276 2 P62263 1 +Protein transport protein Sec23 [IPR037364] 0.4073115496603005 0.9380575522389396 0.3482148344181053 1.0 0.3550630098705349 2 Q15436 1 +SLC12A transporter family [IPR004842] 0.4047233904885106 0.9230209793559896 0.3559962723647376 1.0 0.3623777676440031 2 P55011 1 +Protein phosphatase 2C family [IPR015655] 0.4355987055016225 0.9196940396102832 0.3577326682481887 1.0 0.3639899376160111 3 Q9H0C8,Q15750 2 +Flotillin family [IPR027705] 0.3866062762859909 0.8184461111409809 0.4131025010554547 1.0 0.4196122082697017 2 O75955 1 +AP complex subunit beta [IPR026739] 0.3935275080906193 0.6943966195815683 0.4874335130898957 1.0 0.4944827429686946 3 O00203,Q10567 2 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.3642834034293098 0.6919745708873296 0.4889532984821056 1.0 0.4956028971014968 2 O96005 1 +Cleft lip and palate transmembrane 1 [IPR008429] 0.3642834034293098 0.6919745708873296 0.4889532984821056 1.0 0.4956028971014968 2 O96005 1 +HnRNP-L/PTB [IPR006536] 0.399584551029464 0.5804343544244367 0.561621743498288 1.0 0.5673307319963646 4 Q9UKA9 1 +Protein arginine N-methyltransferase [IPR025799] 0.3884309293185447 0.5279375849466302 0.5975426570364035 1.0 0.6031058980244699 4 Q86X55 1 +Glycoside hydrolase, family 29 [IPR000933] 0.3261080556454185 0.4861037756368961 0.626893590105623 1.0 0.631927815892608 2 Q9BTY2 1 +Alpha-L-fucosidase, metazoa-type [IPR016286] 0.3261080556454185 0.4861037756368961 0.626893590105623 1.0 0.631927815892608 2 Q9BTY2 1 +Cullin [IPR045093] 0.3866580310880811 0.4153364293126369 0.6778956365995534 1.0 0.6830507364976489 5 Q13617,Q93034,Q13616,Q13620 4 +Snf7 family [IPR005024] 0.3368932038834999 0.4129306965549525 0.6796573902084464 1.0 0.6845366873509902 3 O43633,Q96FZ7 2 +Heat shock protein Hsp90 family [IPR001404] 0.3583684040142385 0.3932590892368324 0.6941281310877228 1.0 0.6985213471072653 4 Q12931,P08238,P07900 3 +Ezrin/radixin/moesin-like [IPR000798] 0.3855469435382627 0.3389115382174361 0.7346763720801928 1.0 0.7387028446084568 8 Q9Y4F1,Q9Y2J2,P35241 3 +Type 1 protein exporter [IPR039421] 0.3852301951496759 0.3189660129557766 0.7497522854092082 1.0 0.7532262850467404 6 P08183 1 +Importin beta family [IPR040122] 0.3353836192942585 0.2988691341668593 0.7650398986763052 1.0 0.7679377770803821 4 O00410,Q8TEX9,Q92973 3 +Small GTPase superfamily, ARF/SAR type [IPR006689] 0.3688637656247067 0.2975667497506957 0.7660338553741912 1.0 0.76861200886304 10 P36405,Q9NVJ2,P40616 3 +ThiF/MoeB/HesA family [IPR045886] 0.3487694300518116 0.2677818309931343 0.788867256907015 1.0 0.79118940610733 5 Q13564,Q9UBT2,A0AVT1,P22314 4 +Septin [IPR016491] 0.3301702977458269 0.2039109638101298 0.8384230772036303 1.0 0.8401844702229657 5 Q15019,Q16181 2 +Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998] 0.3303079416531709 0.1478796361302752 0.8824377595085999 1.0 0.8839202252952586 8 P50991,Q99832,P17987,P40227,P78371,P48643,P50990 7 +Glutathione Transferase family [IPR040079] 0.3035391485192387 0.0782070057713438 0.9376633892892412 1.0 0.938056704469312 9 Q13505,P28161 2 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..755c535b8414a28607d4f8e18c3aab3942780164 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1-Cys peroxiredoxin [IPR045020]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-oxoisovalerate dehydrogenase subunit alpha [IPR034616]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S26 [IPR026140]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-keto-steroid reductase [IPR042829]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "4-aminobutyrate aminotransferase, eukaryotic [IPR004631]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "50S ribosomal protein uL4 [IPR013005]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABI family [IPR028457]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 10 [IPR042951]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1 complex subunit sigma [IPR044733]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit ATP5MJ, mitochondrial [IPR012574]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP synthase-coupling factor 6, mitochondrial [IPR008387]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase ARIP4-like [IPR044574]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "ATR-interacting protein [IPR033349]", "Abl interactor 1 [IPR028456]", "Acetate-CoA ligase [IPR011904]", "Acetyl-coenzyme A transporter 1-like [IPR024371]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Actin family [IPR004000]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Activating signal cointegrator 1-like [IPR039128]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active regulator of SIRT1 [IPR023262]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA thioesterase, long chain [IPR016662]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A diphosphatase NUDT19 [IPR039121]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine kinase [IPR001805]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase ALAT1/2-like [IPR045088]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid beta precursor protein binding family B member 1/2/3 [IPR039576]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Anion exchange protein 2 [IPR002978]", "Anion exchange protein [IPR001717]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-10 [IPR031291]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Antigen peptide transporter 2 [IPR005293]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAK [IPR026308]", "Apoptosis regulator BAX [IPR026304]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Apyrase [IPR009283]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arylacetamide deacetylase [IPR017157]", "Arylesterase [IPR002640]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Asparaginyl endopeptidase [IPR043577]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase B [IPR028772]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BTB-kelch protein [IPR017096]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bicaudal-D protein [IPR018477]", "Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [IPR013109]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bud22/Serum response factor-binding protein 1 [IPR037393]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-alcohol phosphatidyltransferase class-II family [IPR016270]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CGG triplet repeat-binding protein 1 [IPR033375]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COG complex component, COG2 [IPR009316]", "COMM domain-containing protein 1 [IPR037351]", "COMM domain-containing protein 10 [IPR037361]", "COMM domain-containing protein 5 [IPR037357]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF complex subunit CPSF4-like [IPR045348]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase activity and apoptosis inhibitor 1 [IPR038991]", "Cat eye syndrome critical region protein 2 [IPR029614]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cationic amino acid transport permease [IPR004755]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein C/Mif2/cnp3 [IPR028386]", "Centromere protein I [IPR012485]", "Centromere protein P [IPR027801]", "Centromere protein Q [IPR025212]", "Centromere protein U [IPR025214]", "Centromere subunit L [IPR025204]", "Centrosomal protein of 44kDa [IPR033603]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Choline transporter-like [IPR007603]", "Choline/ethanolamine phosphotransferase [IPR014472]", "Chondroitin N-acetylgalactosaminyltransferase [IPR008428]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin complexes subunit BAP18 [IPR037931]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homolog 2 [IPR042796]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Claspin [IPR024146]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 137 [IPR026680]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 167 [IPR028194]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 90-like [IPR024461]", "Coiled-coil domain-containing protein 93 [IPR039116]", "Coilin [IPR024822]", "Complex I intermediate-associated protein 30, mitochondrial [IPR039131]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit G2 [IPR024741]", "Conserved oligomeric Golgi complex subunit 5 [IPR019465]", "Conserved oligomeric Golgi complex subunit 6 [IPR010490]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1C [IPR027333]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-7 [IPR031223]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 1 [IPR014807]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP1/Nbp35 [IPR028601]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "D-glucuronyl C5-epimerase [IPR039721]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 16 [IPR028216]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA recombination and repair protein, RecA-like [IPR016467]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IA [IPR000380]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "DUF5568 family [IPR040419]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Dehydrogenase/reductase SDR member 4-like [IPR029511]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxynucleoside kinase [IPR002624]", "Deoxyribonuclease II [IPR004947]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dipeptidyl-peptidase 3 [IPR005317]", "Divergent protein kinase domain 2A/B [IPR020519]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 25-like [IPR044632]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [IPR039485]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 SUMO-protein ligase PIAS1 [IPR027227]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RING2 [IPR037937]", "E3 ubiquitin-protein ligase RNF123/RSPRY1-like [IPR045129]", "E3 ubiquitin-protein ligase UBR7 [IPR040204]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Endonuclease III-like protein 1 [IPR030841]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Ephrin receptor type-A /type-B [IPR016257]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec10-like [IPR009976]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "F-box-like/WD repeat-containing protein Ebi-like [IPR045183]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FLYWCH-type zinc finger-containing protein 1/2 [IPR040312]", "FUN14 [IPR007014]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 2 [IPR030305]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferritin [IPR001519]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fyv10 family [IPR045098]", "Fyv7/TAP26 [IPR013730]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase 2-like [IPR045130]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GOSR2/Membrin/Bos1 [IPR027027]", "GPI ethanolamine phosphate transferase 2 [IPR039527]", "GPI mannosyltransferase [IPR005599]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI transamidase subunit PIG-U [IPR009600]", "GPI-anchor transamidase [IPR028361]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "Galactokinase [IPR000705]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucose-methanol-choline oxidoreductase [IPR012132]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 13 [IPR004139]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 43 [IPR005027]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Groucho/transducin-like enhancer [IPR009146]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "H/ACA ribonucleoprotein complex, subunit Nop10 [IPR007264]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HEXIM [IPR024872]", "HMG-CoA lyase [IPR043594]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 12A [IPR026685]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase XPB/Ssl2 [IPR001161]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histidine-tRNA ligase [IPR015807]", "Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit [IPR004516]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone acetyltransferases subunit 3 [IPR019340]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1 [IPR038035]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase SETD2, animal [IPR042294]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "ING family [IPR028651]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of growth protein 4/5 [IPR028638]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B alpha/beta/delta [IPR011559]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol monophosphatase-like [IPR000760]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integral membrane protein SYS1 [IPR016973]", "Integral membrane protein SYS1-related [IPR019185]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 10 [IPR026164]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 5 [IPR040316]", "Integrator complex subunit 8 [IPR038751]", "Integrin alpha chain [IPR000413]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intracellular chloride channel [IPR002946]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intraflagellar transport protein 81 [IPR029600]", "Intron Large complex component GCFC2-like [IPR012890]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KRR1 interacting protein 1 [IPR018034]", "Kelch-like ECH-associated protein 1 [IPR030563]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore Mis14/Nsl1 [IPR013950]", "Kinetochore protein Spc25 [IPR045143]", "Kintoun [IPR034727]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LIM domain only protein 7 [IPR029978]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "Las1 [IPR007174]", "Learning associated protein 18-like [IPR018784]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lipid droplet-associated hydrolase [IPR019363]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Luc7-related [IPR004882]", "Lunapark family [IPR040115]", "Lupus La protein [IPR002344]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase phosphoprotein 6 [IPR019324]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "METTL16/RlmF family [IPR010286]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MKRN-like [IPR045072]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "Macrophage migration inhibitory factor [IPR001398]", "Magnesium transporter protein 1 [IPR006844]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannose-P-dolichol utilization defect 1 protein [IPR016817]", "Mannosyltransferase ALG2 [IPR027054]", "Med25/PTOV1 [IPR045105]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med20 [IPR013921]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med27 [IPR021627]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribose-1-phosphate isomerase [IPR005251]", "Methylthiotransferase [IPR005839]", "Methyltransferase METTL16/PsiM [IPR017182]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microsomal glutathione S-transferase 1-like [IPR040162]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondria fission 1 protein [IPR016543]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial calcium uniporter regulator 1 [IPR012439]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein Mtm1-like [IPR045315]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit TIM22 [IPR039175]", "Mitochondrial import inner membrane translocase subunit Tim10 [IPR027100]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdenum cofactor biosynthesis C [IPR023045]", "Molybdenum cofactor biosynthesis protein A [IPR013483]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 12 [IPR030576]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetylglucosaminyl phosphatidylinositol deacetylase-related [IPR003737]", "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase [IPR039516]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase 1, beta subcomplex, subunit 6 [IPR019174]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, iron-sulphur subunit 5 [IPR019342]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Nck-associated protein 1 [IPR019137]", "Nectin-2 [IPR033318]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neural cell adhesion [IPR009138]", "Neural cell adhesion molecule 1 [IPR033019]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Non-specific endonuclease [IPR040255]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nuclear MIS12/MIND complex subunit PMF1/Nnf1 [IPR007128]", "Nuclear RNA export factor [IPR030217]", "Nuclear RNA-splicing-associated protein, SR-25 [IPR019532]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 2 [IPR027157]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear hormone receptor [IPR001723]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear speckle splicing regulatory protein 1 [IPR042816]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar and spindle-associated protein 1 [IPR026756]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar protein of 40kDa [IPR037320]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase 6 [IPR037994]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "Nucleotide-sugar transporter [IPR007271]", "NudC family [IPR037898]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ODR-4-like [IPR029454]", "Occludin [IPR002958]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Oligosaccharyltransferase complex subunit OSTC [IPR042416]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 2 [IPR007220]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 6 [IPR008721]", "Origin recognition complex, subunit 6, metazoa/plant [IPR020529]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IB [IPR027256]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PDZ domain-containing protein 8 [IPR039275]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PSME3-interacting protein [IPR039845]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic antigen Ma [IPR026523]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Patatin-like phospholipase domain-containing protein 4 [IPR033902]", "Patatin-like phospholipase domain-containing protein [IPR033562]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1A, chymotrypsin family [IPR001314]", "Peptidase S1C [IPR001940]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal biogenesis factor 11 [IPR008733]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phenylalanyl-tRNA synthetase, class IIc, mitochondrial [IPR004530]", "Phorbol-12-myristate-13-acetate-induced protein 1 [IPR024140]", "Phosducin-like [IPR045037]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [IPR042165]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like [IPR044596]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phospholipase B-like [IPR007000]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Platelet-activating factor acetylhydrolase, eucaryote [IPR016715]", "Platelet-activating factor acetylhydrolase-like [IPR005065]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polycomb protein EED [IPR037352]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA splicing factor [IPR022209]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable E3 ubiquitin-protein ligase makorin-2 [IPR026293]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein CIP2A [IPR042510]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM3C [IPR039219]", "Protein FAM8A1 [IPR039871]", "Protein FMC1 homologue [IPR037667]", "Protein Fyv10/E3 ubiquitin-protein transferase MAEA [IPR027714]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LCHN/Anr2 [IPR018626]", "Protein LIN-9/Protein ALWAYS EARLY [IPR010561]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein Mon2-like [IPR026829]", "Protein NCBP2AS2 [IPR042407]", "Protein NDRG3 [IPR030692]", "Protein Njmu-R1 [IPR028280]", "Protein OS-9-like [IPR045149]", "Protein PCF11-like [IPR045154]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein TFG [IPR033512]", "Protein XRP2 [IPR039093]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C, alpha/beta/gamma types [IPR014375]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF1387 [IPR009816]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF4660 [IPR029089]", "Protein of unknown function DUF719 [IPR007998]", "Protein of unknown function DUF842, eukaryotic [IPR008560]", "Protein of unknown function DUF92, TMEM19 [IPR002794]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein suppressor of sable-like [IPR045124]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein unc-119 homologue A-like [IPR032977]", "Protein virilizer [IPR026736]", "Protein-L-histidine N-pros-methyltransferase [IPR007884]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA methyltransferase [IPR003750]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAB11-binding protein RELCH [IPR040362]", "RAD51-associated protein 1 [IPR026632]", "RFT1 [IPR007594]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II elongation factor ELL [IPR031184]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein Nova-1 [IPR033086]", "RNA-binding region-containing protein RBM41/RNPC3 [IPR045164]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit Pop5/Rpp14/Rnp2-like [IPR002759]", "RNase P subunit p30 [IPR002738]", "RPA-related protein RADX [IPR040893]", "RSBN1/Dpy-21 [IPR026306]", "RZZ complex, subunit Zw10 [IPR009361]", "RZZ complex, subunit Zwilch [IPR018630]", "Rab GDI protein [IPR000806]", "Rab11-family interacting protein class I [IPR037789]", "Rab12 [IPR041830]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab35 [IPR041815]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Rab29/Rab38/Rab32 [IPR030697]", "Ras-related protein Ral [IPR028412]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulophagy receptor 1/3 [IPR043384]", "Reticulophagy regulator 3 [IPR033361]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease P protein subunit Rpp38 [IPR042848]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein 7 [IPR040446]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24e [IPR023438]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27/L41, mitochondrial [IPR019189]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome biogenesis protein Slx9-like [IPR028160]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "Ribosome-releasing factor 2, mitochondrial [IPR030851]", "RidA family [IPR006056]", "Romo1/Mgr2 [IPR018450]", "Root UVB sensitive family [IPR006968]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAGA-associated factor 29 [IPR037802]", "SAP30-binding protein [IPR012479]", "SCAMP [IPR007273]", "SERRATE/Ars2 [IPR039727]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "STEEP-like [IPR029704]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BAF60B [IPR030090]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sds3-like [IPR013907]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/Arginine-related protein 53 [IPR034604]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shikimate kinase/Threonine synthase-like 1 [IPR000623]", "Shikimate kinase/gluconokinase [IPR031322]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smooth muscle protein/calponin [IPR003096]", "Snapin [IPR017246]", "Snapin/Pallidin/Snn1 [IPR028119]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium/solute symporter [IPR001734]", "Sodium:dicarboxylate symporter [IPR001991]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 12 member 9 [IPR030345]", "Solute carrier family 25 member 44 [IPR042164]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sororin protein [IPR018605]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle and kinetochore-associated protein 3 [IPR033341]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 3B subunit 5/RDS3 complex subunit 10 [IPR009846]", "Splicing factor 3B, subunit 5 [IPR017089]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Stromal interaction molecule 1 [IPR030463]", "Stromal interaction molecule [IPR037608]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, cytochrome b556 subunit [IPR014314]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit [IPR000701]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar phosphate transporter [IPR000849]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of hairless-like [IPR040159]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntaxin-3 [IPR031186]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA element modulatory factor 1 DNA binding [IPR022092]", "TB2/DP1/HVA22-related protein [IPR004345]", "TE2IP/Rap1 [IPR039595]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TREX component Tex1/THOC3 [IPR040132]", "Taxilin family [IPR026183]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Telomeric repeat-binding factor 1/2 [IPR017357]", "Telomeric repeat-binding factor 2 [IPR030657]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 15 [IPR042418]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine synthase-like [IPR004450]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A [IPR030549]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription initiation factor TAFII31 [IPR003162]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulator TACO1-like [IPR002876]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 223 [IPR026100]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transmembrane protein TqsA-like [IPR002549]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm3 [IPR040002]", "UAA transporter [IPR013657]", "UAP56-interacting factor [IPR009782]", "UBAP2/protein lingerer [IPR022166]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "UPF0767 family [IPR031933]", "USP39 [IPR033809]", "UV excision repair protein Rad23 [IPR004806]", "UbiA prenyltransferase domain containing protein 1 [IPR026046]", "UbiA prenyltransferase family [IPR000537]", "Ubinuclein-1 [IPR026936]", "Ubiquinol-cytochrome c chaperone, CBP3 [IPR007129]", "Ubiquinol-cytochrome c chaperone/UPF0174 [IPR021150]", "Ubiquinone biosynthesis protein COQ9 [IPR012762]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin domain-containing protein UBFD1 [IPR039120]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-associated protein 1 [IPR038870]", "Ubiquitin-fold modifier-conjugating enzyme 1 [IPR014806]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised conserved protein UCP013899, metal binding [IPR016617]", "Uncharacterised protein family UPF0390 [IPR019034]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family UPF0640 [IPR028183]", "Uncharacterised protein family, TMEM59 [IPR022065]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Ureohydrolase [IPR006035]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar ATPase assembly integral membrane protein Vma21 [IPR019013]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vang-like protein [IPR009539]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "WASH complex subunit 7 [IPR027307]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "Xyloside xylosyltransferase 1 [IPR042465]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YIP1 family member 3 [IPR026637]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter Msc2-like [IPR045316]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA export factor Gle2/RAE1 [IPR037631]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein RRP36 [IPR009292]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7 [IPR028590]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-specific 2-thiouridylase [IPR004506]"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACSS1", "ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFG3L2", "AGA", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANKLE2", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEX1", "API5", "APLP2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFIP1", "ARG2", "ARHGDIA", "ARID1A", "ARID3B", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC6", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATXN2L", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAX", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCL2L13", "BCLAF1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPTF", "BRCA1", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUD23", "BUD31", "BYSL", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf35", "C1orf52", "C2CD5", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf33", "CAAP1", "CAB39", "CAD", "CALR", "CALU", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CAST", "CBR1", "CBR4", "CBX2", "CBX3", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC59", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC37", "CDC40", "CDC42", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK5RAP3", "CDKAL1", "CEBPZ", "CECR2", "CELF2", "CENPC", "CENPI", "CENPL", "CENPP", "CENPQ", "CENPU", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHDH", "CHERP", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHST14", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COIL", "COLGALT1", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF2", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSGALNACT2", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CWF19L1", "CXorf56", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DCAF1", "DCAF16", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DECR1", "DECR2", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAJA1", "DNAJA2", "DNAJC10", "DNAJC13", "DNAJC25", "DNAJC8", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPM1", "DPP3", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EED", "EEF1A2", "EEF1E1", "EEF1G", "EFHD1", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2B1", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENDOD1", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESF1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAM114A2", "FAM120A", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM207A", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIS1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMC1", "FMR1", "FN3KRP", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GCAT", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDI2", "GEMIN4", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GHITM", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLS", "GLUD1", "GM2A", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRPEL1", "GRSF1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDHD5", "HEATR1", "HEBP1", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTRA2", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS10", "INTS13", "INTS14", "INTS3", "INTS5", "INTS8", "IPO4", "IPO5", "IRS4", "ISCU", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KDELR1", "KDELR3", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF5B", "KLC1", "KMT2A", "KMT2B", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LETMD1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMF2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT3", "LRPAP1", "LRPPRC", "LRRC47", "LSM12", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LZIC", "M6PR", "MACF1", "MAEA", "MAGED2", "MAGT1", "MAK16", "MAN1A2", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL9", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPST", "MPV17L2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTR", "MTX1", "MTX2", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYO18A", "NAA15", "NAA40", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NAT10", "NAXE", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF1", "NDUFB10", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NFS1", "NHP2", "NIP7", "NIPBL", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NSA2", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT19", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUSAP1", "NXF1", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH2", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PAWR", "PAXBP1", "PBRM1", "PC", "PCBD1", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PELO", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGS1", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIP4K2C", "PISD", "PITPNB", "PKM", "PKMYT1", "PLA2G15", "PLBD2", "PLEC", "PLIN3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA4", "PNPT1", "POFUT1", "POFUT2", "POLA1", "POLA2", "POLD1", "POLD2", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIE", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2B", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM23", "RBM26", "RBM27", "RBM39", "RBM45", "RBM5", "RBM6", "RBM8A", "RBPJ", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFT1", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPEP", "ROMO1", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RSRC1", "RTCB", "RTFDC1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARS", "SARS2", "SART1", "SBDS", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B5", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35A4", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLK", "SLTM", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", 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b/interpro_homologous_superfamily/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:799a6b28aaaa87ba76652dc6a116abb864fa3bf00a8470ffffa071fcb8ed931c +size 138211 diff --git a/interpro_homologous_superfamily/consensus.joblib b/interpro_homologous_superfamily/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..964938e5ac9bb385dea625c9d599e193a12aebaf --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8e2d2a657dd864447306e2221504b5167ff6209e2939df99243c0d2610604b5d +size 330540 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b750bc995be665f2790d12018d4f99bba20149b0 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,10 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier domain superfamily [IPR023395] 6 25 3.182275555180079 0.0014612272219647 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.011594797392584 0.0142466262053111 0.0004610478660449 2.9874917190946567e-05 0.0020003826549309 +PH-like domain superfamily [IPR011993] 12 43 2.8442781810196003 0.0044512167048063 16.538834951456312 55.366504854368934 -0.1721757009659374 0.6272733937475546 8.168489456557142 10.439569255029584 0.8639046053288412 0.3178368882722004 0.7527002771183884 0.7890872829392844 0.9558550433805562 0.5077762354330623 0.7704257726097611 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 2 6 2.437837373618157 0.0147754195097253 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0506000729453915 0.0561990347849709 0.0056684159955205 0.00262770885776 0.0019443402252438 +Ubiquitin-like domain superfamily [IPR029071] 9 33 2.4186953356206744 0.0155762800256722 11.74757281553398 41.27427184466019 -0.211476259581958 0.623848045693968 5.827984791515399 5.973649110308603 0.7649250476398386 0.2908772909022708 0.1177998166297224 0.1403881914917208 0.3803883597337516 0.2384181501984974 0.1255361586960177 +Peptidase M4/M1, CTD superfamily [IPR027268] 3 5 2.409587730095485 0.0159705558708798 2.111650485436894 5.548543689320389 1.4203309343737989 0.1835434124596617 1.027373025804284 0.6683357213562342 0.9844971330203006 0.2264468231852968 0.0381897723637082 0.0424464003246627 0.0031504918831051 0.0010588751859522 0.0005558041127602 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 3 5 2.409587730095485 0.0159705558708798 2.111650485436894 5.548543689320389 1.4203309343737989 0.1835434124596617 1.027373025804284 0.6683357213562342 0.9844971330203006 0.2264468231852968 0.0381897723637082 0.0424464003246627 0.0031504918831051 0.0010588751859522 0.0005558041127602 +Histidine phosphatase superfamily [IPR029033] 1 6 2.2573334696927594 0.0239872454854244 1.1262135922330097 5.514563106796117 0.7684120115144248 0.3501978831807532 1.087703661549979 0.6771453167512235 0.986671075305162 0.2738673806375665 0.070936999678044 0.0786913117950012 0.0113213926532688 0.062605312422627 0.1967448754466316 +SNARE [IPR010989] 4 7 2.020523390740034 0.0433291263950403 2.4854368932038833 5.364077669902913 0.7966086592831925 0.3585374753437345 1.5079985943563208 1.7302199405020957 1.098385457365192 0.3157194502762394 1.0 1.0 1.0 0.3247468214281712 0.0061301079468053 +MFS transporter superfamily [IPR036259] 2 12 2.0116558023887388 0.0442562326743665 3.6432038834951457 8.356796116504855 0.9436301622284156 0.2543148229816532 1.924895010927015 2.2984539817025564 1.2198539986610124 0.2448337840515702 0.0011325878612304 0.0015498180404582 0.0108939889611676 0.1099245732268714 0.2000499940427514 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a0bc81da8f9447c3e2262de1b5e66abcea934e96 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 950, + "title": "Average number of proteins per term", + "value": 4.670526315789473 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4d24ed54a0aa6ef607841ebf3ed1210fac5eb331 --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9860ec1188c1d7ddf7fcb713bd0982d291276176 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,133 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +FF domain superfamily [IPR036517] 0.9792947266256876 3.900830436322604 9.586328034938418e-05 0.0870502897260595 0.0010601084674558 2 O14776 1 +Haem oxygenase-like, multi-helical [IPR016084] 0.9757360077644788 3.885325579591973 0.0001021928410975 0.0925240004635591 0.0010601084674558 2 P30519 1 +Ribokinase-like [IPR029056] 0.9424134584276944 3.738640060775683 0.0001850184044551 0.1612006428507709 0.0014174797115517 2 P55263 1 +Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080] 0.9314137819475928 3.6896102303284817 0.0002245978963169 0.1921605705125615 0.0015805037148226 2 P52888 1 +Choline/Carnitine o-acyltransferase, domain 2 [IPR042231] 0.9252669039145954 3.6620764830298937 0.0002501791379947 0.2115607464880213 0.0016391262540177 2 P23786 1 +GINS, helical bundle-like domain superfamily [IPR036224] 0.9113555483662252 3.599401617306415 0.0003189502726437 0.261438638206762 0.0019804101896179 2 Q9BRX5 1 +GMP phosphodiesterase, delta subunit superfamily [IPR037036] 0.901326431575546 3.553902031440064 0.0003795605759147 0.3027777105523594 0.0022318436919118 2 A6NIH7 1 +C-type lectin-like/link domain superfamily [IPR016186] 0.8893561954060236 3.4992446156963273 0.0004665783239534 0.3581193174009547 0.0025621353049468 2 Q5KU26 1 +Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155] 0.861533484309285 3.3706924719519384 0.0007497950793633 0.5096189320701213 0.003491692771545 2 Q9H267 1 +Dbl homology (DH) domain superfamily [IPR035899] 0.8563571659657068 3.34653809304833 0.0008182743577673 0.5405287286217455 0.0036494301719232 2 Q9Y4F1 1 +Mitochondrial carrier domain superfamily [IPR023395] 0.7407464749424543 3.182275555180079 0.0014612272219647 0.7507206347956974 0.0056855435046791 25 Q70HW3,Q9Y619,O43772,Q96H78,Q8TBP6,Q86VD7 6 +BAG domain superfamily [IPR036533] 0.8755993169553755 3.1589055806708637 0.0015836278745207 0.778124525827083 0.0059700257174391 3 O95429 1 +Class II aldolase/adducin N-terminal domain superfamily [IPR036409] 0.8146230993206149 3.148979308920101 0.0016384179537023 0.7893955494631955 0.0061039100235969 2 Q9UEY8 1 +FAD-binding, type PCMH-like superfamily [IPR036318] 0.7958589453251437 3.0584766278508546 0.0022246543188777 0.8794602749013817 0.0074155143962591 2 Q15392 1 +FAD-binding, type PCMH, subdomain 2 [IPR016169] 0.7958589453251437 3.0584766278508546 0.0022246543188777 0.8794602749013817 0.0074155143962591 2 Q15392 1 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.8436219528831881 3.013871729591933 0.0025793683503834 0.9140135557111164 0.0081139070624643 3 P52888 1 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.8857807184615142 2.9457009329932027 0.0032222378483488 0.953395977131559 0.0094639771241934 4 P52888,P42892 2 +TRAF-like [IPR008974] 0.7648010352636692 2.9063050294447845 0.0036572473802995 0.969215805525703 0.0103404315812042 2 O43791 1 +C-type lectin fold [IPR016187] 0.8110032362459278 2.863081427322025 0.0041954272979509 0.9815748768373244 0.0115862091077134 3 Q5KU26,Q9UBG0 2 +PH-like domain superfamily [IPR011993] 0.5836791385447676 2.8442781810196003 0.0044512167048063 0.9855649387522796 0.0121164924629398 43 Q13614,Q9BZF3,Q9Y4F1,P50570,Q9Y5P4,P31751,Q06481,Q6WCQ1,P35241,Q8NC96,Q66K14,Q86X55 12 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.7987055016181124 2.8054642136733534 0.0050244160294674 0.9916477707969228 0.0131131737032804 3 P07437,Q9BUF5 2 +Tubulin/FtsZ, C-terminal [IPR008280] 0.7987055016181124 2.8054642136733534 0.0050244160294674 0.9916477707969228 0.0131131737032804 3 P07437,Q9BUF5 2 +Tubulin, C-terminal [IPR023123] 0.7987055016181124 2.8054642136733534 0.0050244160294674 0.9916477707969228 0.0131131737032804 3 P07437,Q9BUF5 2 +Peptidase M41-like [IPR037219] 0.7275962471692083 2.7199882647370353 0.0065284233166513 0.9980153949316478 0.0160847757908663 2 Q96TA2 1 +PABC (PABP) domain [IPR036053] 0.7702265372168189 2.670383368433333 0.0075764687763797 0.9992718840237028 0.0180845360240219 3 O95071,P11940 2 +Malic enzyme, N-terminal domain superfamily [IPR037062] 0.6988029763830537 2.572679827983734 0.0100914515129697 0.9999346386607124 0.0226640164002866 2 P48163 1 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.798964066040789 2.558874156068182 0.0105011747886185 0.9999558918566134 0.0232323829939476 4 P07437,Q9BUK6,Q9BUF5 3 +EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044] 0.7309549007921005 2.4802408688381936 0.0131293657186113 0.9999964745479 0.0275339899176176 3 Q9Y2D4 1 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.8606864150365539 2.437837373618157 0.0147754195097253 0.9999992781006668 0.0296757897129791 6 Q8WUJ1,Q9UMX5 2 +Ubiquitin-like domain superfamily [IPR029071] 0.5844295847266004 2.4186953356206744 0.0155762800256722 0.9999996665995916 0.0307270369712748 33 Q9Y4F1,P46379,Q9Y5A7,Q92575,Q99426,P60520,Q9Y4G8,P35241,Q96K76 9 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.8099090261299893 2.4095877300954855 0.0159705558708798 0.99999977212908 0.0313471654490409 5 Q9UIQ6,Q9NZ08,P55786 3 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.8099090261299893 2.4095877300954855 0.0159705558708798 0.99999977212908 0.0313471654490409 5 Q9UIQ6,Q9NZ08,P55786 3 +Zinc finger, CCHC-type superfamily [IPR036875] 0.7627063774684366 2.391595662797388 0.0167753116686752 0.999999895254299 0.0326478896791461 4 O95639,Q7Z6E9,Q16629 3 +CAP Gly-rich domain superfamily [IPR036859] 0.70619711875887 2.358016330935224 0.0183728846655204 0.9999999776530109 0.0352610917823119 3 Q99426 1 +Ricin B-like lectins [IPR035992] 0.6941747572815464 2.29799997090875 0.0215617907830589 0.999999998984374 0.039774177172633 3 Q86SF2,Q9UBG0 2 +Histidine phosphatase superfamily [IPR029033] 0.8183213683921451 2.2573334696927594 0.0239872454854244 0.9999999999039012 0.0437387393688161 6 Q9NPH0 1 +Moesin tail domain superfamily [IPR008954] 0.6786067914353339 2.2196363816853384 0.0264434605453112 0.9999999999912276 0.0459356803597335 3 P35241 1 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.6535958130653214 2.0922131332112723 0.0364194541888778 0.9999999999999996 0.0594475626794397 3 P10321 1 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.6535958130653214 2.0922131332112723 0.0364194541888778 0.9999999999999996 0.0594475626794397 3 P10321 1 +Profilin superfamily [IPR036140] 0.6014234875444899 2.053573225346738 0.0400170157774997 1.0 0.0641082040280349 2 P07737 1 +G protein alpha subunit, helical insertion [IPR011025] 0.6853653871784087 2.0231715198130136 0.0430554668923108 1.0 0.0681522377371736 4 P04899,Q14344 2 +SNARE [IPR010989] 0.7544747922790787 2.020523390740034 0.0433291263950403 1.0 0.0683179557875605 7 Q13190,O15400,O60499,O14653 4 +MFS transporter superfamily [IPR036259] 0.6903326491947865 2.0116558023887388 0.0442562326743665 1.0 0.069378582575327 12 P41440,Q8NHS3 2 +Ribosomal protein L14 superfamily [IPR036853] 0.5926884503397025 2.0054199122222345 0.0449181747272375 1.0 0.0699545344112716 2 P62829 1 +Formin, FH2 domain superfamily [IPR042201] 0.5901002911679134 1.991102903051424 0.0464695753739781 1.0 0.0715495893116356 2 Q9Y613 1 +Cyclic nucleotide-binding-like [IPR018490] 0.686725236198906 1.8457460670721395 0.0649290849078565 1.0 0.0953213169124438 5 Q8IY17 1 +Sec1-like, domain 2 [IPR027482] 0.6846971734352857 1.8361689721444416 0.0663326700594078 1.0 0.0960610313360326 5 Q9H267,Q96AX1 2 +Sec1-like, domain 1 [IPR043154] 0.6846971734352857 1.8361689721444416 0.0663326700594078 1.0 0.0960610313360326 5 Q9H267,Q96AX1 2 +Sec1-like superfamily [IPR036045] 0.6846971734352857 1.8361689721444416 0.0663326700594078 1.0 0.0960610313360326 5 Q9H267,Q96AX1 2 +Sec1-like, domain 3a [IPR043127] 0.6846971734352857 1.8361689721444416 0.0663326700594078 1.0 0.0960610313360326 5 Q9H267,Q96AX1 2 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.5610435786186473 1.827105798955868 0.0676838635260417 1.0 0.0975715786794228 20 O95831,Q9UHG3,Q96CU9 3 +Coatomer, gamma subunit, appendage domain superfamily [IPR037067] 0.5587188612099732 1.81575292645456 0.0694082812248217 1.0 0.0994537966268185 2 Q9UBF2 1 +AH/BAR domain superfamily [IPR027267] 0.6908465123566225 1.770700565086364 0.0766105084660775 1.0 0.1075036677145844 8 Q9UQB8 1 +Chloramphenicol acetyltransferase-like domain superfamily [IPR023213] 0.696360444502583 1.716361870720045 0.0860958307219428 1.0 0.1176849484688427 6 P23786 1 +Porin domain superfamily [IPR023614] 0.6125112034333609 1.66211017956282 0.0964906848910502 1.0 0.1311389851881227 4 P21796 1 +WW domain superfamily [IPR036020] 0.6363630413389837 1.6614036301667752 0.0966324092156734 1.0 0.1311439839355567 11 O75400,Q96PU5,O95817,O14776 4 +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.5446588450448302 1.593385024073096 0.1110738432461071 1.0 0.1481552832574999 18 P28070,P49721,P28074,Q99436 4 +Rho GTPase activation protein [IPR008936] 0.6472503087582808 1.490454064526417 0.1361048860148681 1.0 0.1783443333987927 6 O00459,Q14C86 2 +Leucine-rich repeat domain superfamily [IPR032675] 0.4799919638754481 1.458331463213159 0.1447492018260527 1.0 0.1888897551301513 24 Q96RT1,Q13641,Q13045 3 +Alpha/Beta hydrolase fold [IPR029058] 0.4740436045488381 1.4455672654567615 0.1482986136036475 1.0 0.1932560808277985 26 P42785,Q9H6V9,Q9HB40,Q4J6C6,Q8NCC3,Q6PIU2,Q9UMR5,P07099,Q9H3G5 9 +F-box-like domain superfamily [IPR036047] 0.4862504043998743 1.3997919697224597 0.1615756232320098 1.0 0.2077088525986594 2 Q8NEZ5 1 +DNA-directed RNA polymerase, insert domain superfamily [IPR036643] 0.4752507279197702 1.335617562451915 0.1816743067754522 1.0 0.2319766013933866 2 P19387 1 +RNA polymerase, RBP11-like subunit [IPR036603] 0.4752507279197702 1.335617562451915 0.1816743067754522 1.0 0.2319766013933866 2 P19387 1 +Translation elongation factor eEF-1beta-like superfamily [IPR036219] 0.4726625687479926 1.3204917695361893 0.1866708821693603 1.0 0.2377176113416787 2 P29692 1 +Translation elongation factor EF1B/ribosomal protein S6 [IPR014717] 0.4726625687479926 1.3204917695361893 0.1866708821693603 1.0 0.2377176113416787 2 P29692 1 +AP-2 complex subunit mu, C-terminal superfamily [IPR036168] 0.5424718246904008 1.3045558504405212 0.1920441300364808 1.0 0.2435806722759102 4 Q9Y2T2 1 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.6003790102394493 1.302722070253677 0.1926696644005927 1.0 0.2440482415740841 7 Q92804,P35637,P98175 3 +Sterile alpha motif/pointed domain superfamily [IPR013761] 0.5842317581835896 1.2938304895274308 0.1957239786504623 1.0 0.2472576857951319 9 Q15375,Q9Y3Z3,Q96JM7 3 +Mannose-6-phosphate receptor binding domain superfamily [IPR009011] 0.5366292279289286 1.2744268338663929 0.2025121874200075 1.0 0.2554934635444982 4 P20645,P11717 2 +Acyl-CoA N-acyltransferase [IPR016181] 0.5766787204604067 1.2212950420981747 0.2219743299151901 1.0 0.278567521029631 8 Q86UY6 1 +Peptidase S1, PA clan [IPR009003] 0.4890809622752249 1.2127896031012195 0.225210271447493 1.0 0.2815128393093663 3 Q7KZN9 1 +Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410] 0.4532513749595626 1.2068266188935255 0.2274989224526877 1.0 0.2839999688962594 2 O60884 1 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.5614042126547141 1.180271272883491 0.2378923398345271 1.0 0.2942678682848969 9 Q9HD20 1 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.5614042126547141 1.180271272883491 0.2378923398345271 1.0 0.2942678682848969 9 Q9HD20 1 +P-type ATPase, A domain superfamily [IPR008250] 0.5614042126547141 1.180271272883491 0.2378923398345271 1.0 0.2942678682848969 9 Q9HD20 1 +SH3-like domain superfamily [IPR036028] 0.4376873984163282 1.1587775012944288 0.2465468905789727 1.0 0.3045767828999012 24 O00459,P07948,Q96PC5,P46108,Q9Y5K6,Q00013,P62993,Q9UQB8,Q8IZP0,P41240 10 +DHS-like NAD/FAD-binding domain superfamily [IPR029035] 0.5447473396235157 1.157868167833498 0.2469178395969105 1.0 0.3046388930091753 5 Q13423,P49366 2 +RmlC-like jelly roll fold [IPR014710] 0.5417052241556325 1.082219939107553 0.2791548106694435 1.0 0.3399025355325433 9 Q8IY17,Q9Y4G8 2 +SH2 domain superfamily [IPR036860] 0.531374993003487 1.0644275156478396 0.2871350743928009 1.0 0.3488152313227746 10 P07948,O00459,P46108,P62993,P41240 5 +SMCs flexible hinge superfamily [IPR036277] 0.5255797294252903 1.06362814896698 0.2874971853955079 1.0 0.3488152313227746 5 Q9UQE7 1 +Alpha-catenin/vinculin-like superfamily [IPR036723] 0.4572815533980637 1.0381533839267176 0.2991986512826741 1.0 0.3609163478753401 3 Q9Y490,P35221 2 +Fibronectin type II domain superfamily [IPR036943] 0.4539229188630054 1.0197495652389172 0.3078472480828043 1.0 0.3692612192912425 3 P11717 1 +Kringle-like fold [IPR013806] 0.4539229188630054 1.0197495652389172 0.3078472480828043 1.0 0.3692612192912425 3 P11717 1 +Band 7/SPFH domain superfamily [IPR036013] 0.5311144565351268 0.9992608416879436 0.317668349409425 1.0 0.3792155480515745 8 P27105 1 +NTF2-like domain superfamily [IPR032710] 0.5368075734515149 0.9739240480134465 0.3300942523807642 1.0 0.3919869247021574 6 O43615,Q13555 2 +Ribosomal protein S11 superfamily [IPR036967] 0.4118408282109305 0.964416631801344 0.3348370870705885 1.0 0.3971226375993247 2 P62263 1 +Alpha/beta knot methyltransferases [IPR029028] 0.4414239482200683 0.9514234866906552 0.3413894423328967 1.0 0.4033830475326515 3 Q9HC36,Q5T280 2 +tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026] 0.4414239482200683 0.9514234866906552 0.3413894423328967 1.0 0.4033830475326515 3 Q9HC36,Q5T280 2 +Myosin S1 fragment, N-terminal [IPR008989] 0.4379577777793996 0.932533275097286 0.3510609984600061 1.0 0.4137815738672529 3 P35580 1 +PPM-type phosphatase domain superfamily [IPR036457] 0.4355987055016225 0.9196940396102832 0.3577326682481887 1.0 0.420081625260543 3 Q9H0C8,Q15750 2 +HAD superfamily [IPR023214] 0.427729319597199 0.908703551129012 0.3635066291928974 1.0 0.4252848494251879 19 Q9HD20,P23634,Q5TFE4,Q969T7 4 +HAD-like superfamily [IPR036412] 0.427729319597199 0.908703551129012 0.3635066291928974 1.0 0.4252848494251879 19 Q9HD20,P23634,Q5TFE4,Q969T7 4 +L27 domain superfamily [IPR036892] 0.4245954692556685 0.8600284005452512 0.3897733872778042 1.0 0.4510167087867405 3 O14936,Q9NZW5 2 +Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882] 0.3840181171142001 0.80362658617163 0.4216126641065809 1.0 0.4860825617733639 2 Q8IU81 1 +Lamin tail domain superfamily [IPR036415] 0.4118296844798863 0.7913728591899641 0.4287264430553155 1.0 0.4907109890392165 3 P20700 1 +Metal-dependent hydrolase, composite domain superfamily [IPR011059] 0.4077669902912659 0.7696811307257927 0.4414890658134371 1.0 0.5004947643469753 3 P27708,Q9BPU6 2 +Metal-dependent hydrolase [IPR032466] 0.4077669902912659 0.7696811307257927 0.4414890658134371 1.0 0.5004947643469753 3 P27708,Q9BPU6 2 +SRP/SRP receptor, N-terminal [IPR036225] 0.3759301197023657 0.7575574383263788 0.4487159679873689 1.0 0.5068729721617128 2 P61011 1 +Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101] 0.3759301197023657 0.7575574383263788 0.4487159679873689 1.0 0.5068729721617128 2 P61011 1 +Death-like domain superfamily [IPR011029] 0.4334512364291866 0.7458258385896153 0.4557726292218214 1.0 0.5141774990991165 4 Q7Z434 1 +PDZ superfamily [IPR036034] 0.3949754661642526 0.7026147184973166 0.4822958874841372 1.0 0.539671487761991 19 P55196,O43464,Q00013,Q8WWI1,Q9Y4G8,Q96RT1 6 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.4718758690135034 0.69466085221725 0.4872678670082182 1.0 0.5445934984209497 7 Q10713,O43847 2 +Rhomboid-like superfamily [IPR035952] 0.4160737825131018 0.6599848334704105 0.5092635621721324 1.0 0.5645278693856777 4 Q8NBM4 1 +HECT, E3 ligase catalytic domain [IPR035983] 0.4565740326521975 0.6253572830048862 0.5317365916079075 1.0 0.5867012334814311 7 Q05086,Q96J02,Q96PU5 3 +Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098] 0.3384018117114122 0.5505383592116088 0.5819501742899023 1.0 0.6361940915712395 2 O75695 1 +Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223] 0.3384018117114122 0.5505383592116088 0.5819501742899023 1.0 0.6361940915712395 2 O75695 1 +RNA-binding domain superfamily [IPR035979] 0.275631795035499 0.5002523990157375 0.6168973667836948 1.0 0.6706124643893249 128 P52597,Q9UBU9,P18615,Q86U42,Q86U06,Q71RC2,P62995,P98175,Q8WVV9,Q5T8P6,Q86V81,Q13247,O43390,P51991,Q99729,Q15233,Q9NW64,O75494,P55795,P98179,Q16629,P07910,Q8IY67,P38159,Q92879,P31942,Q14011,Q15717,Q13310,P31943,Q96E39,Q92804,Q9Y5S9,Q8WXF1,O95319,P23588,P35637,P52298,Q9UKA9,O14979,O60506,P11940,P78332 43 +Nucleotide-binding alpha-beta plait domain superfamily [IPR012677] 0.2738546769645158 0.4766121223526191 0.6336383496296827 1.0 0.6855995810343947 126 P52597,Q9UBU9,P18615,Q86U42,Q86U06,P62995,P98175,Q8WVV9,Q5T8P6,Q86V81,Q13247,O43390,P51991,Q99729,Q15233,Q9NW64,O75494,P55795,P98179,Q16629,P07910,Q8IY67,P38159,Q92879,P31942,Q14011,Q15717,Q13310,P31943,Q96E39,Q92804,Q9Y5S9,Q8WXF1,O95319,P23588,P35637,P52298,Q9UKA9,O14979,O60506,P11940,P78332 42 +EF-hand domain pair [IPR011992] 0.3017088601304753 0.465129902612306 0.6418384332034035 1.0 0.6936820381606751 50 Q9BUP0,Q8N163,Q96D71,Q66K14,P17655,Q9BRK5,Q14257,Q9NWM8,O43852,P14649,O95302,Q96AY3,P80303 13 +ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034] 0.3121967000970479 0.4159406789425012 0.6774534118049087 1.0 0.7305116245342375 2 P06576 1 +HSP90, C-terminal domain [IPR037196] 0.3583684040142385 0.3932590892368324 0.6941281310877228 1.0 0.7442683121143755 4 Q12931,P08238,P07900 3 +LEM/LEM-like domain superfamily [IPR011015] 0.398849081890499 0.370059389115915 0.7113382402544666 1.0 0.7584414458380957 6 P50402,Q86XL3 2 +Protein-tyrosine phosphatase-like [IPR029021] 0.3792293758695285 0.3392229281583551 0.7344417980327047 1.0 0.7787050313962829 10 Q13614,Q99956 2 +Prefoldin [IPR009053] 0.3393479076841551 0.3145254236049186 0.7531220102366734 1.0 0.7976208581101891 4 O60925 1 +HIT-like superfamily [IPR036265] 0.3316731985856285 0.2844703248132644 0.7760499724083518 1.0 0.816008777602345 4 Q9BX68 1 +Ubiquitin-activating enzyme [IPR035985] 0.3487694300518116 0.2677818309931343 0.788867256907015 1.0 0.8253567115216567 5 Q13564,Q9UBT2,A0AVT1,P22314 4 +Tetratricopeptide-like helical domain superfamily [IPR011990] 0.2762937017820376 0.2544713082081438 0.7991314674023571 1.0 0.8333423644700759 74 Q92791,Q9Y5A7,Q32P28,P49321,Q6DKK2,O75718,Q96DB5,Q9UJX3,O75153,O00231,P13674,Q9Y3D6 12 +FERM superfamily, second domain [IPR035963] 0.3529936196386785 0.2372285554933428 0.8124794844275232 1.0 0.8447034719890829 10 Q9Y4F1,Q9Y2J2,P35241 3 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.3530759168175196 0.2279761188991271 0.8196648060541931 1.0 0.8500890455802221 9 Q03518,P08183 2 +C2 domain superfamily [IPR035892] 0.2924963791262084 0.163058363907641 0.8704724817658989 1.0 0.893998765056869 20 P05771,Q96PU5,Q6WKZ4 3 +SWAP/Surp superfamily [IPR035967] 0.3365727243278268 0.1592880990975555 0.8734418965932447 1.0 0.8960796995287068 6 Q8IWZ8,O15042,Q15459,Q8IX01,Q8IWX8 5 +FERM/acyl-CoA-binding protein superfamily [IPR014352] 0.3197073370212482 0.1531103219766801 0.8783112760961864 1.0 0.8981654599476611 12 P35241,Q9H3P7 2 +Heavy metal-associated domain superfamily [IPR036163] 0.2682847896440186 0.1429883520796785 0.8862993803572246 1.0 0.9037271626159904 3 P35670,Q04656 2 +6-phosphogluconate dehydrogenase, domain 2 [IPR013328] 0.2877954030430494 0.1354606597839736 0.8922476664552736 1.0 0.9085051266157664 4 P31937,Q16836,P52209 3 +Nucleic acid-binding, OB-fold [IPR012340] 0.2700985216850836 0.12050317080395 0.904084568011806 1.0 0.9185885985146692 38 P16989,Q9Y3B2,P67809,P25205,P33991 5 +Phosphoribosyltransferase-like [IPR029057] 0.3038641505018243 0.0761377185190149 0.9393095321788548 1.0 0.9503131582214188 6 Q14558,Q06203 2 +K Homology domain, type 1 superfamily [IPR036612] 0.2646451012806869 0.0707827906837037 0.9435706285111704 1.0 0.9536086139208638 24 Q92667,Q15637,O75525,Q96I24,P61978,Q06787,P51114,Q07666,Q9NQT5,Q13868,Q96AE4,Q96PU8 12 +Exoribonuclease, PH domain 2 superfamily [IPR036345] 0.2908895035321212 0.0491508214458068 0.9607991026619028 1.0 0.9679312274960844 6 Q96B26 1 +PNPase/RNase PH domain superfamily [IPR027408] 0.2908895035321212 0.0491508214458068 0.9607991026619028 1.0 0.9679312274960844 6 Q96B26 1 +TGS-like [IPR012676] 0.2899254940071233 0.0472839552358774 0.9622869156459432 1.0 0.9680531166120552 6 Q9NYK5,Q9Y295,Q9BW92,Q9NTK5,P55039 5 +Beta-grasp domain superfamily [IPR012675] 0.2900194426442054 0.046441825904208 0.9629581002088335 1.0 0.9680531166120552 7 Q9NYK5,Q9Y295,Q9BW92,P21912,Q9NTK5,P55039 6 +LSM domain superfamily [IPR010920] 0.2685672354830081 0.0043073883353731 0.9965632119772884 1.0 1.0 10 Q9UK45,P62310,Q9Y4Y9 3 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e633326bfaf2f7f147e1d910a073a80dad62d9f3 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP synthase-coupling factor 6 superfamily, mitochondrial [IPR036204]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioester hydrolase/BAAT, N-terminal [IPR042490]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "Apyrase superfamily [IPR036258]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Beta-trefoil domain superfamily [IPR036358]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DENN domain, C-terminal lobe [IPR043153]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA glycosylase [IPR011257]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IA, central region, subdomain 1 [IPR013824]", "DNA topoisomerase, type IA, central region, subdomain 2 [IPR013825]", "DNA topoisomerase, type IA, central region, subdomain 3 [IPR013826]", "DNA topoisomerase, type IA, core domain [IPR023405]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DUSP-like superfamily [IPR035927]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Deoxyhypusine synthase superfamily [IPR036982]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FCS-type zinc finger superfamily [IPR038603]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FTO, C-terminal domain superfamily [IPR038413]", "Fe-S cluster assembly domain superfamily [IPR034904]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like [IPR012347]", "Ferritin-like superfamily [IPR009078]", "Ferrodoxin-fold anticodon-binding domain superfamily [IPR036690]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarate reductase/succinate dehydrogenase, transmembrane subunit [IPR034804]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "H/ACA ribonucleoprotein complex, subunit Nop10 superfamily [IPR036756]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-hairpin-helix, base-excision DNA repair, C-terminal [IPR023170]", "Helix-loop-helix DNA-binding domain superfamily [IPR036638]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "I/LWEQ domain superfamily [IPR035964]", "IFT81, N-terminal domain superfamily [IPR043016]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrase-like, N-terminal [IPR017856]", "Integrin alpha, N-terminal [IPR028994]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Lipid transport protein, beta-sheet shell [IPR015819]", "Lipovitellin-phosvitin complex, superhelical domain [IPR011030]", "Longin-like domain superfamily [IPR011012]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex subunit 25, PTOV domain superfamily [IPR038196]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthioribose-1-phosphate isomerase, N-terminal [IPR027363]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "Moesin tail domain superfamily [IPR008954]", "Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily [IPR036522]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nuclear hormone receptor-like domain superfamily [IPR035500]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PCGF Ub-like fold discriminator superfamily [IPR038227]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PH-like domain superfamily [IPR011993]", "PIN-like domain superfamily [IPR029060]", "PINIT domain superfamily [IPR038654]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S1, PA clan, chymotrypsin-like fold [IPR043504]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Putative deacetylase LmbE-like domain superfamily [IPR024078]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RBP-J/Cbf11, DNA binding domain superfamily [IPR037095]", "RGS domain superfamily [IPR036305]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RNase P subunit Pop5/Rpp14/Rnp2-like domain superfamily [IPR038085]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RRF superfamily [IPR036191]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scaffold protein Nfu/NifU, N-terminal domain superfamily [IPR036498]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Set2 Rpb1 interacting domain superfamily [IPR038190]", "Seven-hairpin glycosidases [IPR036026]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Sodium/glucose symporter superfamily [IPR038377]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfatase-modifying factor enzyme superfamily [IPR042095]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Telomere repeat-binding factor, dimerisation domain superfamily [IPR036507]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonine synthase, N-terminal domain superfamily [IPR037158]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transcriptional regulator TACO1-like, domain 3 [IPR026564]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Triosephosphate isomerase superfamily [IPR035990]", "Tryptophan synthase beta subunit-like PLP-dependent enzyme [IPR036052]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UROD/MetE-like superfamily [IPR038071]", "UbiA prenyltransferase superfamily [IPR044878]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-associated protein 1, C-terminal [IPR042575]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vitellinogen, beta-sheet N-terminal [IPR015816]", "Vitellinogen, open beta-sheet, subdomain 1 [IPR015817]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "YEATS superfamily [IPR038704]", "YebC-like [IPR029072]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG13", "ALG5", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL10", "ARL2", "ARL3", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5J", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATRX", "ATXN10", "AURKA", "AURKB", "B3GAT3", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BCAS3", "BCAT2", "BCKDHA", "BCKDHB", "BCL2L13", "BCOR", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C1QBP", "C2CD5", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2A", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPV", "CEPT1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHORDC1", "CHP1", "CHRAC1", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT9", "CNP", "COA7", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCPS", "DCTN1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDC4", "EDF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FIS1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GORASP2", "GOSR2", "GOT1", "GOT2", "GPATCH8", "GPD2", "GPI", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMPDH2", "ING5", "INTS1", "INTS11", "INTS14", "INTS4", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL3", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LYAR", "LYN", "LYPLA1", "LZIC", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED16", "MED25", "MEPCE", "METTL16", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPG", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL4", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKIPSD", "NCL", "NCOA5", "NCOR1", "NDRG3", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAF1", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEK9", "NELFE", "NENF", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF3", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGL", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD6", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PUS1", "PWP1", "PWP2", "PYCR1", "PYCR2", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REPS1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "RP2", "RPA1", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RREB1", "RRM1", "RRM2", "RRP12", "RRP7A", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RTCB", "RTF1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SCAF11", "SCAF8", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC37A4", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMU1", "SMYD3", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPECC1L", "SPEN", "SPNS1", "SPOP", "SPOUT1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STUB1", "STX10", "STX12", "STX3", "STX5", "STX6", "STX7", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "THEM6", "THNSL1", "THOC1", "THOC3", "THOC6", "THOP1", "THYN1", "TIAL1", "TIGAR", "TIMM10", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKT", "TLE3", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMED8", "TMEM14C", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBFD1", "UBIAD1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UFC1", "UFD1", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YKT6", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H13", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZCCHC17", "ZCCHC3", "ZEB2", "ZFR", "ZMYND8", "ZNF148", "ZNF280C", "ZNF281", "ZNF346", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF644", "ZPR1", "ZRANB2"], "leading_proteins": ["ABCB1", "ABI1", "ACBD3", "ACP6", "ADD3", "ADK", "AFDN", "AIFM1", "AKAP1", "AKT2", "ALYREF", "ANAPC7", "ANKLE2", "AP3M1", "APLP2", "ATP13A1", "ATP2B4", "ATP5B", "ATP7A", "ATP7B", "BAG3", "BAG4", "BAG6", "BAIAP2", "CAD", "CALU", "CAMK2G", "CAPN2", "CARM1", "CASK", "CCAR2", "CD2AP", "CELF1", "CELF2", "CHERP", "CIRBP", "CLUH", "COL4A3BP", "COLEC12", "COPG2", "COX15", "CPSF4", "CPT2", "CPVL", "CRK", "CRTAP", "CSK", "CTNNA1", "CYB5D2", "DHCR24", "DHPS", "DNAJA2", "DNM2", "DPYSL5", "DRG1", "DRG2", "DUSP9", "ECE1", "EEF1D", "EFHD1", "EIF4B", "ELAVL1", "EMD", "EPB41L3", "EPHA7", "EPHX1", "ERAP1", "ERBIN", "EXOC6B", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "FARP1", "FBXO22", "FHOD1", "FIS1", "FKBP10", "FKBP14", "FKBP9", "FLII", "FMR1", "FOXRED1", "FUBP1", "FUBP3", "FUS", "FXR1", "GABARAPL2", "GALNT7", "GAPVD1", "GINS3", "GNA13", "GNAI2", "GOSR2", "GRB2", "HADH", "HIBADH", "HINT2", "HLA-C", "HMOX2", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPLL", "HNRNPR", "HSP90AA1", "HSP90AB1", "HTRA2", "IGF2R", "ILKAP", "IRF2BP1", "ITCH", "KHDRBS1", "KHDRBS3", "L3MBTL3", "LARP4", "LDAH", "LMNB1", "LMO7", "LNPEP", "LSM3", "LSM5", "LSM7", "LYN", "M6PR", "MAVS", "MCM3", "MCM4", "ME1", "MFSD8", "MIA2", "MPP1", "MPP6", "MPRIP", "MRC2", "MRM3", "MRPL39", "MSTO1", "MTMR2", "MYH10", "MYL6B", "NAA40", "NAE1", "NASP", "NCBP2", "NCEH1", "NECAP1", "NEDD4L", "NELFE", "NENF", "NNT", "NONO", "NPEPPS", "NRDC", "NT5C3B", "NT5DC1", "NUB1", "NUCB2", "NXF1", "OLA1", "OSBPL6", "P3H1", "P3H4", "P4HA1", "PABPC1", "PABPC4", "PABPN1", "PCYOX1", "PFDN1", "PFN1", "PGD", "PIK3R2", "PLA2G15", "PMPCA", "PNPLA6", "POLR2C", "PPAT", "PPT2", "PRCP", "PREPL", "PRKCB", "PRPF40A", "PRPSAP1", "PSMB2", "PSMB4", "PSMB5", "PSMB7", "PSMD11", "PSPC1", "PTBP2", "QKI", "RAB11FIP1", "RAPGEF2", "RAVER1", "RBBP6", "RBM10", "RBM22", "RBM23", "RBM26", "RBM3", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RCN2", "RDX", "REPS1", "RMDN1", "RP2", "RPL23", "RPS14", "SAMHD1", "SCPEP1", "SDF4", "SDHB", "SF1", "SF3A1", "SLC19A1", "SLC25A15", "SLC25A20", "SLC25A26", "SLC25A40", "SLC25A42", "SLC25A44", "SMC3", "SPOP", "SPOUT1", "SRP54", "SRSF10", "SRSF6", "SRSF7", "STOM", "STX10", "STX5", "STX7", "SUGP1", "SUGP2", "SYNCRIP", "TAB1", "TAF15", "TAP1", "TARS2", "TBC1D9B", "TBCB", "TCERG1", "THOP1", "TIMM44", "TLN1", "TPBG", "TRA2B", "TRAP1", "TTC19", "TUBB", "TUBB6", "U2SURP", "UBA1", "UBA2", "UBA6", "UBAC2", "UBE3A", "UBR5", "UBXN4", "UNC119B", "USP47", "VDAC1", "VPS33A", "VPS33B", "YBX1", "YBX3", "YME1L1"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..81d937b8c4aa4cead8ac742b5044c359ac35cfa7 --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:02c7da5cacafe6b3ce9a61836b7f329c6ad2eac087ececa416c863df5aeee8b1 +size 69380 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..037a4341f77bbcc1cbfd0da5547f0c9302965e81 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 3.25 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7876bf70a0e1f4a73e7569b4155f6ccd6d9299ba --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..82394f25407d78d3d534dc14afea81193bd65166 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.5614042126547141 1.180271272883491 0.2378923398345271 0.6626619676053747 0.2378923398345271 9 Q9HD20 1 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..67c8525426520b20ca7d8caa8ff3cd7359114701 --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP7A", "ATP7B", "EIF5A", "FASN", "LDLR", "SLIT2"], "leading_proteins": ["ATP13A1"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..fc6d8bc29e540b18e60be225087c56a64b46835e --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]", "1": "Leucine-rich repeat, typical subtype [IPR003591]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..f19662425f886297180fb1386aa662125818c4b3 --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f8ded4302801628a7df02b0ea2dd5927891793e7abd7498733bf2bba8347f103 +size 190769 diff --git a/interpro_repeat/advanced/plot_1.png b/interpro_repeat/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..349cff422dbb4d1c36fbfa81c04d992fdfe7d53c --- /dev/null +++ b/interpro_repeat/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f0fc7f8f2c47379caea9e6c8c733493e69a3b5888009f256decf7d0a889bede4 +size 187746 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..84257128b1ced2de7727e53afeef5d1d3ca58b9f --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]", "1": "Leucine-rich repeat, typical subtype [IPR003591]", "2": "Leucine-rich repeat [IPR001611]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..afdac1d44e9ab690c0646a070c971145149653ea --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a3b36d98c214a91657d199ca0ea6b0c6e2f1c4dea1fbbe81adca50792e6a79bb +size 145233 diff --git a/interpro_repeat/basic/plot_1.png b/interpro_repeat/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..48f1e26384725ab229d671785f4fcfe152d8d8a5 --- /dev/null +++ b/interpro_repeat/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f08298cdb9a831727f6bc266358e2a25ee9e003c68f56a8726bdde6387c4266d +size 140626 diff --git a/interpro_repeat/basic/plot_2.png b/interpro_repeat/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..7770877fe5772f3b06b053d185be836319f7b24e --- /dev/null +++ b/interpro_repeat/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:471d0cb6ba0c2ac70678d181a1027b2de4bac8e622f69f8ef933244d57a6a939 +size 133406 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..e27e4ad8890a84e9a8d4a9fa164d6db5c9c6fc4a --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9d70b07a4ef7bc769817406ed2e4b216284640770675104dffba8836321dafee +size 86038 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8beec8bc181a46599da60683aa2ed8a483519734 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 6 25 3.182275555180079 0.0014612272219647 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.011594797392584 0.0142466262053111 0.0004610478660449 2.9874917190946567e-05 0.0020003826549309 +Leucine-rich repeat, typical subtype [IPR003591] 5 12 2.2184682910119067 0.026522919295898 4.490291262135922 13.313106796116504 -0.3794289556948225 0.5646814188290152 2.6635626395081915 2.79241744769417 0.7830924352126281 0.2956886956400376 0.0249993394561183 0.0305319028295214 0.1039407380726692 0.048897845662748 0.0557014909025289 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..064877a41ea097c25589e886d07f2be29d9c202f --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 75, + "title": "Average number of proteins per term", + "value": 5.266666666666667 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..27d57fd22b75caca888fcd03c1a1eaad6a5f9c51 --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..42bdb352d9941453237aee2d3b6dd83daffde4fa --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,10 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.7407464749424543 3.182275555180079 0.0014612272219647 0.1038721524336191 0.0047648713759719 25 Q70HW3,Q9Y619,O43772,Q96H78,Q8TBP6,Q86VD7 6 +Leucine rich repeat 4 [IPR025875] 0.8437089474209647 3.014269999415575 0.0025759844573318 0.175887394344571 0.0077279533719956 3 Q13045 1 +Leucine-rich repeat, typical subtype [IPR003591] 0.731451896209021 2.2184682910119067 0.026522919295898 0.8668228154634673 0.051005614030573 12 O94813,Q13641,Q13045,Q9UFC0,Q96RT1 5 +HEAT repeat [IPR000357] 0.7026130410897579 1.9204569760071637 0.0548002026582308 0.9854027351343768 0.093409436349257 5 Q8TF05,O00410,P30154 3 +Leucine-rich repeat [IPR001611] 0.5796337077109732 1.873205715383704 0.0610399834039767 0.9911175567020006 0.0974042288361331 19 O94813,Q13641,Q13045,Q9UFC0,Q96RT1 5 +HEAT, type 2 [IPR021133] 0.4464517841423019 0.7713839576317082 0.4404793810635752 1.0 0.4930739340263901 13 Q8TF05 1 +Tetratricopeptide repeat 2 [IPR013105] 0.389967637540459 0.6757827765336826 0.4991785715225489 1.0 0.5505646009439878 3 Q02790,Q14318 2 +Spectrin repeat [IPR002017] 0.4488568672644921 0.629693117507158 0.5288953864056749 1.0 0.5666736282917946 9 Q8WXH0,Q03001,P46939 3 +Pentatricopeptide repeat [IPR002885] 0.3554548397539588 0.3808345832039719 0.7033259958629918 1.0 0.7326312456906166 4 O75127,Q96EY7,Q92552 3 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..02eda04097744eb96411b83ab54fc3dec90d1a4e --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "FG-GAP repeat [IPR013517]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Fis1, C-terminal tetratricopeptide repeat [IPR028061]", "Fis1, N-terminal tetratricopeptide repeat [IPR028058]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hs1/Cortactin [IPR003134]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "Integrin alpha beta-propellor [IPR013519]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PQ-loop repeat [IPR006603]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "ACTN1", "ACTN4", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC1", "ARMC6", "ARMCX3", "ARPC1A", "ASPH", "BARD1", "BCOR", "BIRC6", "BOP1", "BUB3", "CAST", "CDC16", "CDC23", "CDC27", "CDC40", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "COA7", "COLEC12", "COPA", "COPB2", "CORO1C", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "EDC4", "EED", "EHMT1", "EHMT2", "EIF3I", "ELP2", "EMC1", "EMC2", "EPPK1", "ERBIN", "FIS1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "GCN1", "GEMIN5", "GLG1", "GLS", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HUWE1", "IGF2R", "ILK", "INTS4", "IPO4", "IPO5", "ITGAV", "JUP", "KAT7", "KDELC1", "KDELC2", "KDM2A", "KEAP1", "KIAA1468", "KIDINS220", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "L3MBTL3", "LARP1", "LASP1", "LDLR", "LRBA", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "MACF1", "MAP4", "MAU2", "MED16", "MKI67", "MPDU1", "MPHOSPH8", "MRPS27", "MTCH1", "MTCH2", "MTPN", "NAA15", "NASP", "NEK9", "NHLRC2", "NIPBL", "NISCH", "NLE1", "NOL10", "NOP2", "NOP9", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "P4HA1", "PAFAH1B1", "PAK1IP1", "PDCD11", "PHIP", "PIK3R4", "PLEC", "PLRG1", "PLXNB2", "POLR2A", "PPID", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PREB", "PRKCSH", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM3", "PWP1", "PWP2", "RACK1", "RAE1", "RAI14", "RANBP2", "RANGAP1", "RBBP5", "RBBP7", "RCC1", "RCC2", "RNH1", "RPAP3", "RRP9", "SART3", "SCML2", "SCRIB", "SEC31A", "SEH1L", "SEL1L", "SGTA", "SHCBP1", "SIN3A", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STK11IP", "STRAP", "STRN", "STRN4", "STUB1", "SUGT1", "SYNE2", "TAGLN2", "TBL1XR1", "TBL2", "TBL3", "TEX10", "THOC3", "THOC6", "TLE3", "TMTC3", "TOMM34", "TOMM70", "TPBG", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "XAB2", "XPO1"], "leading_proteins": ["DST", "ERBIN", "FKBP4", "FKBP8", "FLII", "IPO5", "LRWD1", "MRPS27", "PPP2R1B", "PPP4R1", "PTCD1", "PTCD3", "SLC25A15", "SLC25A20", "SLC25A26", "SLC25A40", "SLC25A42", "SLC25A44", "SLIT2", "SYNE2", "TPBG", "UTRN"]} \ No newline at end of file diff --git a/msigdb_gobp/advanced/idx2term.json b/msigdb_gobp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..416bcec900336c9a1a034c385ee2c8aa511de972 --- /dev/null +++ b/msigdb_gobp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transmembrane transport", "1": "Protein targeting to mitochondrion", "2": "Organic acid transmembrane transport", "3": "Mitochondrial transport", "4": "Protein targeting", "5": "Protein localization to mitochondrion", "6": "Mitochondrial transmembrane transport", "7": "Endocytosis", "8": "Immune response regulating signaling pathway", "9": "Protein 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0.0012066818666679 1.4764355477494626e-05 +Mitochondrial transmembrane transport 9 57 3.0270364105900427 0.0024696420868692 19.070388349514563 50.63834951456311 1.9310146760091371 0.188342667216329 9.760351579527285 3.939196260509299 1.9786128158557912 0.3017981993827387 0.0004736768421969 5.111567422339664e-05 1.429145151632323e-06 5.918077284044873e-06 4.982931949194838e-05 +Response to l glutamate 1 5 2.840609275128661 0.004502744337381 1.029126213592233 4.37378640776699 1.2967513270419406 0.258405010407401 0.7465949978845596 0.5879801140961596 0.7687098467942305 0.2572187080379352 1.0 1.0 0.0031504918831051 0.0188064524051028 0.0667973519023849 +Endocytosis 24 96 2.8325006467165013 0.0046185472754793 25.6626213592233 116.14077669902912 0.4088637809343856 0.6347066552957155 9.675324480764845 15.608206311139906 1.1645342915127963 0.3689266363473043 0.4460207232677019 0.5023005139274972 0.2428661097136191 0.0436638008119444 0.0100008422948278 +Immune response regulating signaling 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64.95873786407768 311.3543689320388 0.199755337930638 0.8517569288715414 18.30421847391998 33.62955899493757 0.556704960232788 0.2772693072558876 0.3480662159315025 0.4383612959865569 0.1544203492712333 0.0454376005085482 0.0282340747822436 +Regulation of blood pressure 5 17 2.5945423624524526 0.0094716940497538 5.762135922330097 17.737864077669904 1.3077123393993415 0.1882731913471478 2.2751770017499977 2.3871059987956724 1.372929386780725 0.2480453688154592 0.0258221453234932 0.0315268496209905 0.0022887430854204 0.0026843919056765 0.0208782102708868 +Regulation of immune response 24 101 2.567601025563776 0.0102404944651464 25.00242718446602 119.80339805825244 0.248728055937711 0.7234553499352745 8.655908467072013 12.491655004997526 0.7490545850270482 0.335364410227988 0.2375661956944922 0.2898460679412252 0.0820247002855072 0.4764393352818312 0.4266462589238736 +Inorganic anion transport 11 29 2.5515179864623407 0.0107254787886217 9.900485436893204 25.351941747572816 1.3590123122148194 0.2025490755989976 4.608697956226863 4.352203003870329 1.5972877171217004 0.2769639658120273 1.0 1.0 0.0285769937968429 0.0063798653120075 9.938303442299928e-05 +Regulated exocytosis 7 32 2.534904994944932 0.0112477826201935 9.385922330097088 34.342233009708735 0.5889869251407832 0.528096964379338 3.868480531815476 4.573760415025692 0.9122431884356956 0.3457208176316948 0.4118557095629309 0.4463627535095094 0.3281099840481742 0.0758363007333116 0.235869744438015 +Purine nucleoside biosynthetic process 1 5 2.5088674387678784 0.0121118927641818 1.4611650485436891 5.742718446601942 0.8935109670252933 0.3592786141720023 1.2698698816998135 0.508968486969168 1.0201063575252725 0.3098922359465458 1.0 1.0 1.0 0.0231366382468947 0.0808987135784085 +Purine ribonucleoside salvage 1 5 2.5088674387678784 0.0121118927641818 1.194174757281553 5.087378640776699 0.7525597745497481 0.4015392353821809 1.3351720912111715 0.2990858602087254 0.9698061350109142 0.3038187137036782 1.0 1.0 1.0 0.0082211090226218 0.0306262454905026 +Nucleoside salvage 1 5 2.5088674387678784 0.0121118927641818 1.194174757281553 5.087378640776699 0.7525597745497481 0.4015392353821809 1.3351720912111715 0.2990858602087254 0.9698061350109142 0.3038187137036782 1.0 1.0 1.0 0.0148625463558957 0.0536294240020009 +Inositol phosphate metabolic process 2 5 2.495475335353695 0.0125788499853463 1.9611650485436891 6.633495145631068 0.1060725017289505 0.5348601326232459 1.3841848051111982 1.9104069656092335 0.8960336690054825 0.2907485257932541 1.0 1.0 0.327507803675052 0.0764078368784309 0.3172421403160574 +Nerve development 1 6 2.483844975131483 0.0129972376038121 1.5679611650485437 7.463592233009709 0.9323166733630548 0.322181793723066 1.371606215406715 1.1303984643014222 0.9327393846140116 0.2711478939504144 0.0153499938960131 0.0188245552589776 0.0666692325567911 0.2887846572413305 0.6339668129638776 +Establishment of protein localization to membrane 18 87 2.4827509363842744 0.0130372206667053 23.133495145631063 87.3616504854369 1.231448880072231 0.4195243824117992 8.397245527204214 9.510228790351464 1.3947369206386535 0.4065372973031916 0.2197644086573051 0.07440901727418 0.0465553733545724 0.0040246499403502 0.0045449891893328 +Protein localization to membrane raft 1 5 2.4707416327106277 0.0134833194237424 1.4077669902912622 3.9466019417475726 0.6995898605489175 0.3935219612382615 1.1611585543864895 0.8516478070075068 0.9757696678130928 0.2997431266177076 0.0298283100591577 0.0331691185540615 0.0018609890552042 0.0113265963942617 0.0415253310696985 +Plasma membrane organization 4 21 2.46965524241016 0.0135243322382325 7.099514563106796 28.24514563106796 0.6737258386983643 0.4958528160030953 3.5234718862626195 4.368421626063976 0.8695791931528731 0.3271220115282837 0.2965016962340118 0.0576595399457578 0.0428883183388871 0.04644869055857 0.1958516399710682 +Fatty acid transmembrane transport 3 8 2.464002810314058 0.0137395034156577 2.3519417475728157 6.720873786407767 1.487456141723218 0.1763040127694548 1.5547987465385102 1.1092073674791965 0.7935702169981724 0.2103298472796338 0.0011687386103089 0.0014481500629001 0.0056684159955205 0.000142755965642 0.0019443402252438 +Lipoprotein localization 3 6 2.4450093039456067 0.0144848405227893 1.7451456310679612 4.762135922330097 1.33870340128666 0.2150435313503844 1.1193794779630346 1.3835803073772095 0.999398972942542 0.2555578059866495 1.0 1.0 1.0 0.0328731354880699 0.0019443402252438 +Regulation of erad pathway 0 5 2.444880844129276 0.0144900005744195 2.0024271844660193 6.449029126213592 0.6710358947065599 0.4273068846088207 1.332015748193602 0.952678405750194 0.8726601892197801 0.2893902603244691 0.0749529906412748 0.083126337411673 0.1596960736798767 0.357118555081159 0.214697112815727 +Protein transmembrane import into intracellular organelle 3 14 2.4357256183807725 0.0148619530668183 4.951456310679611 13.45631067961165 1.503963012554726 0.1758225015375162 2.735521961789203 1.4944992929031071 1.2360761671845495 0.245991671368161 0.0073328074064037 0.0003865639533612 0.0001815434943904 0.0056128198685199 0.0134356018089951 +Organic acid transport 11 50 2.424007241719468 0.0153502993822902 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 0.0210461508241911 0.0278996799404129 0.0101994394473641 0.000119244422606 0.0009041719279526 +Nitrogen compound transport 161 561 2.4160208053780545 0.0156911647357163 134.15533980582524 569.4538834951456 0.9072063241864304 0.6401677607980054 37.1767641393764 58.81145048559368 1.470232145086419 0.4303798393104362 0.2453476058819306 0.2178540340283598 0.2574874483776735 0.0002358110474578 5.747557083727356e-07 +Pattern recognition receptor signaling pathway 6 25 2.3996359078571587 0.0164113863208048 6.783980582524272 30.48543689320388 0.3893983283533752 0.5277852242642479 3.0860531364168065 4.421623999132768 0.9404779897396882 0.3335139395352661 0.3719757450801538 0.4043878907472013 0.0837371519329494 0.2606698116599699 0.2581422813734477 +Macromolecule depalmitoylation 1 5 2.399237198024822 0.0164292683223754 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 1.0 1.0 0.1094892401774078 0.2550529546148332 0.1114297880404725 +Regulation of response to extracellular stimulus 1 5 2.385479570464748 0.0170568697267112 1.0364077669902914 4.466019417475728 1.2416795343104177 0.2058666180593168 0.8221064046230258 0.7766686887277909 1.0462594039989206 0.2178110962907249 1.0 1.0 0.1008375048293403 0.027832231049335 0.0958131716431155 +Vesicle mediated transport 95 323 2.376636087804372 0.0174713153229943 80.64805825242719 354.7718446601942 0.3002670711784583 0.7468304035232791 23.646053491950397 43.46537941024834 1.061791523718338 0.3560152131667141 0.8251951887193876 0.8764137279550579 0.7673887908218229 0.099412966208792 0.0270173984489161 +Mitochondrial respiratory chain complex assembly 10 42 2.371794497060759 0.0177019333226597 14.427184466019416 38.300970873786405 1.6683402305651691 0.229838901803248 5.648441561419256 5.588363345618 1.6629328950455762 0.3088219725228932 0.0069937811107839 0.0094231818265578 0.0017929291584427 0.0015917790382586 0.001359110489082 +Regulation of skeletal muscle tissue development 1 6 2.366458091349913 0.0179592074189618 1.5266990291262137 5.065533980582524 0.5140376375767518 0.4827072365041409 1.189258468766583 1.1461528966231134 0.8919004132487386 0.3036148350962652 0.0506000729453915 0.0561990347849709 0.0056684159955205 0.0328731354880699 0.1114297880404725 +Regulation of neurotransmitter transport 2 14 2.366261811556674 0.0179687324206918 4.310679611650485 14.723300970873789 0.5798599621807663 0.5275671173973583 2.1305868930888012 2.005124690866229 0.733411238914484 0.3046457770774066 0.0241876062382683 0.0295498589150116 0.1009015630926116 0.1537817902530961 0.5116292368990515 +Response to food 1 5 2.363609370668861 0.0180978838263576 1.720873786407767 5.783980582524272 1.3281223897944048 0.1823213242558801 0.9790282548915298 0.8299231919143666 1.0823564620426191 0.211054619984942 1.0 1.0 0.1180585699575878 0.0382400085743442 0.127646400127658 +Embryonic heart tube development 0 5 2.3631001118505868 0.0181227732323689 1.3932038834951457 5.800970873786408 0.4671790151602789 0.3328586203421327 1.1599097835626424 1.1943227471644264 1.1899911587922487 0.2586146658185882 0.2053073615131935 0.225839943305071 0.4014202890149608 0.7283143347992781 0.9277854810429116 +Somatic diversification of immune receptors via somatic mutation 0 5 2.31840431361248 0.0204273578456108 1.5970873786407769 5.842233009708738 0.4117560170730587 0.426937860883498 1.54944125918537 0.7832362934246239 1.055920551903701 0.3055647908581022 0.0506000729453915 0.0561990347849709 0.1094892401774078 0.2550529546148332 0.4477841210026768 +Negative regulation of leukocyte migration 1 5 2.3163590127986597 0.0205386746998461 1.5655339805825244 6.388349514563107 1.0839414642274992 0.2862432737648586 1.19995002173864 1.2770035444730965 0.9459956297737524 0.2624453160295969 1.0 1.0 0.1432798584585485 0.0561137872346343 0.1789941624672536 +Peroxisome fission 3 5 2.298937725727213 0.0215084757782209 1.6019417475728157 3.9805825242718447 0.8016205424992385 0.3969435702023293 1.0505643959342583 1.2086306343048052 0.9137030061633076 0.3025779217908124 1.0 1.0 1.0 1.0 0.0536294240020009 +Synaptic transmission dopaminergic 0 5 2.293315985780863 0.0218298195525739 1.3932038834951457 4.691747572815534 -0.0041539491938544 0.5579772277824983 1.061576235633875 0.9826800358129654 0.8655058463650758 0.2879809624221355 0.0423440523288004 0.0470522829573702 0.0921025797166938 0.2175647207167039 0.390305373111191 +Respiratory chain complex iii assembly 1 5 2.2925241290880014 0.0218754168293895 1.8470873786407769 5.160194174757281 1.360931378136811 0.1995688008303064 1.0650749835200868 1.2360161344522411 1.0120439004969468 0.2366879233397748 0.0340178825746634 0.0378187125466048 0.0743799864466655 0.0148625463558957 0.0536294240020009 +Proteolysis 73 360 2.290836848509195 0.0219728515680928 82.13349514563107 384.1650485436893 0.3937128320128939 0.7591937859483255 23.57335472164496 35.5242559243431 1.030244592288769 0.3605545225308969 0.0869893778772193 0.1401948086804333 0.0269426141091312 0.0282025645996368 0.0015510930976825 +Mitochondrial ribosome assembly 0 5 2.290647504282308 0.0219838090824011 0.8058252427184466 4.677184466019417 0.7953090201512811 0.3745199653307256 1.066327081709945 0.9952137083036932 0.8901066244801383 0.2744591955708645 0.0298283100591577 0.0331691185540615 0.0653907127050202 0.1577810442013011 0.2927037483377068 +Formation of extrachromosomal circular dna 0 5 2.2839045444394905 0.0223771415042997 1.2427184466019416 4.871359223300971 0.3346202818185375 0.4342309628183224 1.3013511978498191 1.3312725123078977 1.0984359113559583 0.3048494268056453 0.0587865218066201 0.0652597674910206 0.1265462710440741 0.290751966651369 0.4998540513040848 +Positive regulation of toll like receptor signaling pathway 0 5 2.27154931009525 0.0231137454739782 1.2936893203883495 5.031553398058253 1.0578528534380236 0.3141679357263049 1.0138166762254122 0.5543075051408229 0.7960587950562075 0.2703423316965778 0.0669039716584752 0.0742352733278267 0.1432798584585485 0.3247468214281712 0.5470232014102338 +Vascular process in circulatory system 9 29 2.269589986032594 0.0232324717777063 8.218446601941748 31.361650485436893 0.5302527350177477 0.4259259059419516 3.6564678051714665 4.365329555745678 1.181021277396986 0.3310828049268227 0.0120303650134611 0.0160945082736304 0.0219950308691545 0.0014642245811675 0.0071317114339288 +Protein import into mitochondrial matrix 2 11 2.267106167680958 0.0233837409014792 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 0.0018441232039667 4.557535944516599e-05 0.0003602808960722 0.0051503840765812 0.0329439287769651 +Neutral lipid biosynthetic process 2 8 2.2605741942854185 0.0237856372352758 2.1067961165048543 6.288834951456311 1.1186547336258812 0.1821371148552785 1.2515048910859687 1.3298556757746482 1.2887117600293918 0.213034599641239 1.0 0.1221118561195742 0.0274603336438859 0.0267619345648551 0.1392306203824235 +Intracellular lipid transport 5 15 2.260083115733494 0.0238160928379429 3.2475728155339807 12.529126213592232 1.0333463606041455 0.2805251274605093 1.854375285913986 2.478377603832177 1.0146678848168829 0.2521579143644115 0.0088279525326587 0.0108643857486399 0.0398064357050217 0.0001216265378748 0.0044578499400519 +Regulation of muscle organ development 2 8 2.2578031012948228 0.0239579377946566 2.092233009708738 7.640776699029126 0.4349984526380754 0.5411056432957212 1.6164319643031806 1.656727203798676 0.7847888155998787 0.298066676195091 0.0986950754944635 0.1093006244161378 0.0219975904219434 0.0195244436529747 0.1068437246174296 +Negative regulation of inflammatory response to antigenic stimulus 1 5 2.257508751069514 0.0239763032931497 1.4635922330097086 5.060679611650485 0.3778208142338718 0.5031031490493427 1.507629370622294 1.4068858139407798 0.9208022859904784 0.3032829106068845 1.0 1.0 0.1349531130589082 0.307957256786686 0.1615113588580296 +Monovalent inorganic cation homeostasis 10 30 2.256429396619244 0.024043752347066 9.014563106796116 27.87378640776699 1.1567920478867002 0.2845186374336156 4.051822262152646 3.607380814764068 1.4117439861533438 0.3149022278800241 1.0 1.0 0.5071521873221705 0.0018794473463126 3.962247606886656e-05 +Nucleobase containing small molecule biosynthetic process 1 6 2.2551432097588253 0.0241243411891445 1.7135922330097086 6.725728155339806 0.7645590390237343 0.3868941709719335 1.5487262880443011 0.5167281344531495 1.0510813905138674 0.3156372982117756 1.0 1.0 1.0 0.0382400085743442 0.127646400127658 +Glycosyl compound biosynthetic process 1 6 2.2551432097588253 0.0241243411891445 1.7621359223300972 6.927184466019417 0.7674599123201137 0.3848892158216302 1.5816678247150102 0.68587612099484 1.0539983320068638 0.3161304697180149 1.0 1.0 1.0 0.062605312422627 0.1967448754466316 +Ion transmembrane transport 35 163 2.2470384932272194 0.0246375671551526 47.09466019417476 154.11893203883494 1.555073205784263 0.3634279635891347 19.61122797656 15.97124025754773 1.9676287128633565 0.411597796705808 0.3155179165511552 0.3775589691339882 0.0122120396511153 0.0016475838172334 0.0024827914948958 +Cellular monovalent inorganic cation homeostasis 9 28 2.246225050534836 0.0246895964581039 8.191747572815533 25.12378640776699 1.1978511848260835 0.2636491484517694 3.558748260132903 2.9783551257949803 1.4212259473978417 0.3021468238591936 1.0 1.0 0.4461675288226883 0.000643303268372 2.7913079286263463e-05 +Neuron development 32 163 2.2391479168038484 0.0251462933840986 34.62135922330097 181.34708737864077 0.2741713926873628 0.7656699386252992 12.599789260723686 22.778234719870852 0.7085731328386405 0.3174955318913259 0.1651019759347755 0.2238362898140197 0.4776642419550729 0.207470069121748 0.3589279244970937 +Motor neuron axon guidance 1 5 2.2373909378287027 0.0252608003055205 2.3907766990291264 5.361650485436893 -0.2110710241337478 0.4966649478755087 1.4598884046461125 1.264828625014118 0.9818182905966252 0.3026854184981101 1.0 1.0 1.0 0.3247468214281712 0.1789941624672536 +Retrograde transport vesicle recycling within golgi 4 5 2.237062986909593 0.0252822236327341 1.397984886649874 3.851385390428211 0.5160062000587197 0.4271871782408855 1.2202307952704057 1.8027628796069737 1.1714472405082752 0.3210107152834051 1.0 1.0 1.0 0.1981219124770219 0.0075416763583454 +Neurotransmitter transport 3 23 2.230039660772132 0.0257448100005919 6.665048543689321 26.191747572815533 0.4855466408473005 0.5442577786721134 3.0345009262529348 3.012857536994118 0.8354081034116676 0.3113132472759617 0.0739320432585179 0.0889868259730537 0.2640710535308501 0.4634409820203541 0.5680417593550081 +Regulation of neuron projection development 18 61 2.2222089291028286 0.0262691893096558 13.592233009708735 69.32038834951456 0.4627708713262993 0.6269884749906404 5.824182751460114 9.346058399998094 0.798447623110489 0.3496779713708587 0.6964730420906815 0.7350205673250183 0.4879671288236435 0.1248505787071662 0.1080740693648936 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 2 17 2.215079315201568 0.0267546209353681 3.648058252427184 15.189320388349516 0.4775458796767456 0.549302963282761 2.2240785408411177 1.684619897283117 0.7394953476423776 0.2911116126801303 0.1878492322003874 0.2068720246529641 0.0108939889611676 0.1099245732268714 0.2000499940427514 +Peptide catabolic process 4 10 2.214971703179976 0.0267620068297191 3.871359223300971 10.351941747572816 1.5413280472635258 0.1625248535751528 1.454973091229298 0.9501768442987896 1.1353491763523988 0.2229381591694359 0.0029705548573364 0.0036723611473879 0.0007461625149634 7.054294597105141e-05 0.0001939038931951 +Organic cation transport 2 7 2.20826502205889 0.0272258041003263 2.191747572815534 5.524271844660194 1.626219676916526 0.1372808582950073 1.481153399412497 1.209546654977186 0.871004228766265 0.1892257790071234 0.0036281326260298 0.0044823878286489 0.0010099703116007 0.0135296171343662 0.0166601206234055 +Anion transport 22 78 2.20697621753571 0.027315720905551 26.953883495145632 69.53155339805825 1.854216838065017 0.2425457725148559 12.138973160217668 8.434296289414672 2.014686633079497 0.3448588040224388 0.5825216357262895 0.6220632145766474 0.012510098203701 0.0003568865728054 9.428509552376472e-05 +Endomembrane system organization 47 150 2.2051317301720115 0.0274448520864571 47.08980582524272 169.73058252427185 0.8987911429216844 0.5600148744834964 15.914797198368843 20.49740065572335 1.4161383035869868 0.4170367608227654 0.5019162346444834 0.2845607441622844 0.3151963186303143 0.1463576583198403 0.0069176510736349 +Neuron differentiation 34 194 2.1987620736316416 0.0278948445805491 39.79611650485437 214.22815533980585 0.1406334423130582 0.8173940203730433 16.334405420842412 25.486649531945528 0.6060452870674871 0.2836433485410458 0.1369297045501615 0.1959297023065149 0.5319237415592086 0.3330644041249924 0.5541116057924872 +Chloride transport 3 13 2.198127003154584 0.027940056714353 4.33252427184466 12.12621359223301 1.0302584084066435 0.2341882174183942 2.3624510960969567 2.26059366569241 1.2797232968088257 0.2563105728143979 1.0 1.0 0.0038117145357013 0.007920049564759 0.0198874102408346 +Er associated misfolded protein catabolic process 0 7 2.194720009073651 0.0281836885141111 1.5242718446601942 6.502427184466019 0.6359135499975663 0.449421546369746 1.3317968021500073 0.6053915783561082 0.8489485509943865 0.2958326997322626 0.0506000729453915 0.0561990347849709 0.1094892401774078 0.2550529546148332 0.4477841210026768 +Toll like receptor signaling pathway 4 13 2.190168105886808 0.0285120473980533 3.6529126213592233 14.475728155339803 0.4591583663944621 0.4629288770135975 2.064121680704246 2.5201890058346033 0.9793418922124256 0.3026110620517385 0.2651720683406856 0.290515894493261 0.0307515849952898 0.2468458051395524 0.2575298632789512 +Xenobiotic transport 4 5 2.175323689279547 0.0296058685297229 1.693827160493827 4.08641975308642 0.9732407293076591 0.2870054952103567 1.1547374966527622 1.4159369001791104 1.1259148135419206 0.2680466782257013 0.082934142330337 0.0919337377678228 0.0155240337321844 0.0834574734746242 0.069181328144546 +Mast cell activation involved in immune response 1 6 2.1651877038486904 0.0303733136092387 1.4077669902912622 6.279126213592233 0.631049278533974 0.4332010280138884 1.3666406492392495 1.6077033047515217 0.8569260570409337 0.2789310375738414 1.0 1.0 0.2147385524083838 0.4587195489148998 0.3415430015926662 +Chemical homeostasis 43 183 2.16393200700193 0.0304695680547728 43.762135922330096 177.7597087378641 0.7082111793088889 0.511106347874914 13.668464281922288 17.87763227716401 1.3204137511810292 0.4179418895476048 0.4355622271569757 0.2795969656279524 0.1674308857789419 0.0087711346051242 0.0014993826111093 +Immune response regulating cell surface receptor signaling pathway 7 23 2.161185807266277 0.0306809893092501 6.776699029126213 27.74271844660194 0.136139815526792 0.6569804635275405 4.022224759534535 4.3512993694161155 0.7512753157901814 0.2976989793111175 0.4118557095629309 0.4463627535095094 0.6943670866160305 0.7995688785723946 0.3749065481714448 +Bone remodeling 3 8 2.1611081568253288 0.0306869856399822 2.012135922330097 8.191747572815533 0.5468180618257266 0.3931395839581789 1.401229799996741 1.3580503781098845 1.0682234655932243 0.2933332619823408 1.0 1.0 1.0 0.0720513532108381 0.1254299298894934 +Regulation of vascular permeability 1 7 2.151670308673254 0.0314233302397963 2.883495145631068 7.405339805825243 -0.2539181193924132 0.4877662965194773 1.8580758962927757 1.57753360128169 0.9510023640387432 0.299018398287362 0.0789520148513954 0.0875404472016038 0.1677870330809631 0.0762921742488627 0.232790248880933 +Regulation of pattern recognition receptor signaling pathway 4 16 2.1506550218655662 0.0315034389682538 4.691747572815534 19.70873786407767 0.80673262224624 0.4173389113947272 2.517825740704142 3.173406084005513 0.919675411949683 0.3119180769844089 0.2358123919905848 0.2588687133858448 0.1194965359594502 0.1896820159952031 0.1785456633921929 +Regulation of toll like receptor signaling pathway 3 9 2.1493564478662592 0.0316061550392623 2.587378640776699 9.50485436893204 0.9772136844316576 0.3297728067967737 1.666236944633112 1.8466647258935645 0.9012634534298872 0.2761306672489575 0.1664042855086975 0.1835089509173778 0.0614247268920475 0.2707185745648809 0.1428427753867574 +Ph reduction 6 13 2.1474470387484232 0.0317577092340073 4.422330097087379 12.509708737864075 1.1966830084586066 0.1930048880851129 1.91475781321527 1.7851607614701208 1.4167744165903868 0.2497649393583847 1.0 1.0 1.0 0.0004989114687539 3.6656062743218894e-05 +Skeletal muscle organ development 5 24 2.1472834241238017 0.0317707246401737 6.334951456310679 24.08252427184466 0.124533183769639 0.657573298381775 2.981242613729274 3.0190311306539193 0.742964346268656 0.2922652420181553 0.311673131235772 0.3403437958043751 0.2002076911198734 0.1553404749607282 0.2346049969536484 +Regulation of regulated secretory pathway 4 17 2.1330234403798305 0.03292280336773 5.135922330097087 19.024271844660195 0.5532028818011353 0.482650154445206 2.517120190261048 2.8085156919839167 0.8466655843360735 0.3050640843792452 0.2619651223910598 0.2870659866655126 0.1454623761357323 0.2403501019229617 0.2483380072891435 +Protein insertion into membrane 7 29 2.1152428284671423 0.03440925640113 9.861650485436892 27.67718446601942 1.4180388387951812 0.2751856944202687 4.426616888970974 3.3195747527036987 1.508549988584809 0.3318307488597651 0.1983685689752137 0.0248381956323572 0.0128487417044244 0.0345596402774107 0.0028309580035984 +Lipid localization 13 71 2.113385953610958 0.0345677472162093 20.1504854368932 74.27912621359224 1.3966421040883936 0.3001252105784707 7.306180038477171 9.39465098860316 1.572418240819249 0.3627304234720817 0.0024951070244636 0.0040145834990033 0.0053334692213979 0.0075338259116371 0.010488671779503 +Lymphocyte activation 21 91 2.111057647317176 0.0347673571900422 19.75242718446602 96.97815533980582 0.2587104991344978 0.7054244518764566 7.147670469313885 9.69771309720366 0.6795078753957892 0.3167596875043957 0.2012258183150869 0.2479141332613593 0.6761325305099404 0.5066030558681369 0.2842259257063307 +Retrograde transport endosome to golgi 12 31 2.1101814001502617 0.034842733993109 8.844660194174757 34.00485436893204 0.6408100896550543 0.5235396612667444 4.365036019054001 3.8497226893137166 0.9745365654790862 0.3516062635557995 0.3026090861586128 0.3306605597140526 0.1897338295109766 0.3262227255278284 0.3721082210217046 +Positive regulation of neuron differentiation 0 8 2.099809099044421 0.0357456375130798 2.441747572815534 9.097087378640778 0.1489217986910376 0.4752014853635246 2.2799260877069525 1.0636497261494449 1.0912419199569945 0.312731807854903 0.1771950337940978 0.1952735388158895 0.3530974878629287 0.6691111110298131 0.6462073064888063 +Synaptic transmission glutamatergic 0 6 2.0936619204122104 0.0362901073758834 2.0558252427184467 6.41747572815534 -0.0177928519523734 0.5951960784120235 1.6052976763373412 1.214989486906933 0.8067443864527312 0.2956666961095761 1.0 1.0 1.0 0.5870305126491255 0.8319684561457903 +Negative regulation of mrna catabolic process 11 24 2.091157616927524 0.0365139372191547 9.169902912621358 24.631067961165048 0.5652120707700043 0.4958815262040553 4.097153521759381 1.8459627491120816 1.1372403168685192 0.3560626632344691 1.0 1.0 0.3530974878629287 0.0230341265569123 0.0642230888772536 +Intrinsic apoptotic signaling pathway in response to dna damage 7 23 2.0905878816297125 0.0365650229965333 5.191747572815534 23.4004854368932 0.4729571891933678 0.5742196556826167 2.43550394585209 2.759326595293978 0.7661559213706911 0.3096443051481624 0.0414038035219773 0.0502821167245636 0.0353550186833354 0.1083386684032722 0.0275555017969666 +Response to bacterium 13 54 2.089277928358037 0.0366827120327333 11.235436893203884 58.29126213592233 0.1154865730357222 0.623946124032815 4.342207231820677 6.938189053279808 0.7858164052781929 0.3116148730227279 1.0 0.6591545990918732 0.1632643902509063 0.0887792265974184 0.1812632609588971 +Regulation of membrane lipid distribution 3 5 2.0867181214753403 0.0369136222088224 2.2475728155339807 5.5 0.9490281853542848 0.2470521989607894 1.5110816970578842 2.070950253254846 1.235309366119274 0.2447223644308076 1.0 0.1221118561195742 0.0274603336438859 0.1383652025719425 0.038957699017471 +Purine ribonucleoside metabolic process 3 8 2.079152084425401 0.0376033741249761 2.063106796116505 7.834951456310679 1.2047777662844132 0.2574288772305114 1.199068432200366 0.6246876870736083 0.9870596763535292 0.2611531847589775 1.0 1.0 1.0 0.0074273483269255 0.0077153530289291 +Ribonucleoside metabolic process 3 8 2.079152084425401 0.0376033741249761 2.1189320388349513 8.12621359223301 1.1914157696469383 0.2635896161542528 1.2648845164842024 0.7462477223524518 0.9827848183963048 0.2624193088278075 1.0 1.0 1.0 0.0195244436529747 0.0264052115091236 +Localization within membrane 26 167 2.0786515913723527 0.0376493853769568 43.83252427184466 179.48543689320388 0.7329824809593914 0.5973922945503244 12.803162929787796 21.32668417309247 1.133148805830878 0.4087008058998355 0.1529411429497824 0.0803352629500962 0.1809163962518047 0.045088458803862 0.0904310416832435 +Dendrite extension 2 5 2.0768751678893382 0.0378130822030142 1.9101941747572817 4.983009708737864 0.4584882879901075 0.4930646609262248 1.3105964554706686 1.31355985221178 0.9343901793929332 0.3157604471196771 1.0 1.0 0.191600110602388 0.0983610682747182 0.2873869680451539 +Torc1 signaling 3 6 2.074310690428092 0.0380504656059923 2.849514563106796 7.021844660194175 0.0375156141741917 0.6080161681841268 2.032902835628969 1.1307736397764294 0.7915635497664079 0.2962479957256252 0.159133749222444 0.1755724648168266 0.3209553841799009 0.2526409373615763 0.5817058860938368 +Central nervous system neuron development 1 10 2.0677523778200064 0.0386633138599985 2.3640776699029127 11.609223300970871 0.0190214721993429 0.5388327448827857 2.176322469008906 1.840803006141132 0.915363202324922 0.298877761777515 1.0 1.0 1.0 0.3247253528067797 0.6809842898626863 +Regulation of cellular ph 10 23 2.066895343012801 0.0387440166630244 6.885922330097087 20.844660194174757 1.215766922704761 0.2375185297794358 2.9319293283093293 2.765976649626597 1.4143296516981956 0.2875299337708636 1.0 1.0 1.0 0.0011113418092766 1.62135696065995e-05 +Regulation of ph 10 23 2.066895343012801 0.0387440166630244 6.890776699029126 20.859223300970875 1.2151699598837196 0.2373503364294603 2.930458126920059 2.7746402510870145 1.4154672965603718 0.2873526492076106 1.0 1.0 1.0 0.0015231541907095 2.947606515230474e-05 +T cell homeostasis 1 6 2.0635879449614394 0.0390568015473107 1.7111650485436891 5.427184466019417 0.3175576411827722 0.4948259111815926 1.3225349306017935 1.6106559102173 0.956519419315456 0.3032064248421641 1.0 1.0 0.191600110602388 0.0983610682747182 0.2873869680451539 +Glycerophospholipid catabolic process 2 10 2.0613863971529978 0.0392661915553813 2.216019417475728 7.563106796116505 0.8419758607208171 0.2558936783676348 1.405411068501889 1.391164232085279 1.2384126210044872 0.2497846504551273 1.0 0.0742352733278267 0.0100519320580488 0.0062267265321947 0.0391317335840731 +Homologous chromosome pairing at meiosis 4 9 2.0602003120311267 0.0393793951094596 2.4975728155339807 8.245145631067961 0.965829654578573 0.3348869860078453 1.4047402178514554 0.97323438747629 0.9242483632276672 0.2995534430572119 0.082934142330337 0.0919337377678228 0.1758008751515455 0.0834574734746242 0.0140088487662649 +Lytic vacuole organization 10 23 2.0540577296932185 0.039970104595306 8.677184466019417 23.79368932038835 1.067589638534915 0.1668002350701783 2.8744208086829883 3.077266940940983 2.0111064761459874 0.2496786569477077 0.2291339878948418 0.2516504230112798 0.4407605172427877 0.0571243888921134 0.0001178913204702 +Adenylate cyclase activating g protein coupled receptor signaling pathway 2 5 2.0495151285646247 0.0404117700451016 1.980582524271845 5.936893203883495 -0.4342864371579057 0.4610144412237807 1.439596643375126 1.7915383795201314 1.0199249152327816 0.3097773127088958 1.0 1.0 1.0 0.1637924032376012 0.1744319172289541 +Small rna loading onto risc 0 5 2.0491497715991085 0.0404474718692136 1.7718446601941749 4.922330097087379 -0.1357497037578151 0.5285470818380246 1.4418783242989464 1.169510065774782 0.9381562375101012 0.307678307685116 1.0 1.0 0.1094892401774078 0.2550529546148332 0.4477841210026768 +Sterol transport 4 22 2.046913278642523 0.0406666000858815 5.516990291262136 23.23058252427185 0.3564989162781894 0.4550431454343515 2.7566693478017315 3.339632072416373 1.1016145306573315 0.3225081354886266 0.2555101444842079 0.2801168002074996 0.1388614812827933 0.0824194625829831 0.1090704253919419 +Regulation of systemic arterial blood pressure 1 8 2.046553602908898 0.0407019343328023 1.9514563106796117 7.480582524271845 0.6591644372092078 0.3227631999327531 1.1543807719023411 1.5318976272183211 1.1594175747176596 0.2663405748898474 0.0068626635511563 0.0084566179175882 0.031373049189738 0.1552222190730896 0.1624267369126913 +Regulation of vesicle mediated transport 18 106 2.0425063950044984 0.041101325727618 24.555825242718445 117.33252427184466 0.2091879024365628 0.7679552913580993 8.949930305556254 13.223750714091672 0.6695514077553656 0.3058083256414907 0.4236601323351722 0.4788451615876514 0.1010569970097573 0.1850944968717132 0.1264112495101845 +External encapsulating structure organization 5 21 2.0347215198933903 0.0418789016003371 6.233009708737864 24.611650485436893 0.4933150664413553 0.5761144283300919 2.7919923063541368 3.9981379396708774 0.7808928343017973 0.3215391690746272 0.4014698271890586 0.4354616437047781 0.6821824234140106 0.320496060053052 0.5075379767705799 +Membrane organization 64 219 2.0304914482663974 0.0423066095608795 62.02427184466019 223.60922330097088 0.9560408776070136 0.5603311757674675 21.467957454898308 21.375973545731355 1.611091026762519 0.4273954777865132 0.6737488484953102 0.2485042018361758 0.0674887916082271 0.0177079628004242 3.311778662214068e-05 +Modified amino acid transport 1 6 2.030134263516425 0.0423428935536098 2.029126213592233 5.587378640776699 1.6181581718562612 0.1578136127091599 1.2124460606928238 1.444653995706506 0.7704353439327314 0.2037484924456972 0.0032915927643824 0.0040679264544396 0.0155240337321844 0.0834574734746242 0.069181328144546 +Regulation of sterol transport 0 7 2.022603730603578 0.0431140192733787 2.2645631067961167 7.949029126213592 -0.2660435952469734 0.4696867674075412 1.5281839445392789 1.3346844393150472 0.977377779136872 0.2786928507413737 0.133195547841817 0.1471951297158956 0.2732850813359189 0.5553918894123164 0.4776440234819522 +Protein insertion into mitochondrial inner membrane 3 7 2.0211907851111155 0.0432600192482737 2.45873786407767 5.665048543689321 0.6692509200083531 0.3406754428009103 1.501050234026552 1.645659707056692 1.2686438529444872 0.3125184360343283 1.0 0.0561990347849709 0.0056684159955205 0.00262770885776 0.0019443402252438 +Cellular component morphogenesis 26 117 2.0089958936487635 0.0445375692214802 29.817961165048544 132.93446601941747 0.0314200755217484 0.7461931622021263 12.05361677657582 16.684335902896763 0.7312955885385684 0.3072439636957093 0.05725650912963 0.0831316701599267 0.1874457777772731 0.2925580812894572 0.6586818655361908 +Regulation of retrograde protein transport er to cytosol 3 5 2.0089321350124623 0.0445443313998938 0.9757281553398058 2.529126213592233 0.3873860690502761 0.4252905547793056 0.8529749218837659 1.1370316548232635 1.3209946528406633 0.3304319788075073 1.0 1.0 1.0 1.0 0.4477841210026768 +Positive regulation of cell cell adhesion 11 27 1.998491347393351 0.0456634170769365 6.548543689320389 29.79126213592233 0.2392641305343646 0.6381877105722645 3.259798197270223 3.572429669961151 0.7925488926612984 0.3104905639319101 0.4195293342887257 0.4544030019669794 0.7032010689619301 0.3591436934277615 0.1496247278822182 +Regulation of glucose transmembrane transport 3 10 1.9975626222979583 0.0457640989344008 3.2985436893203883 11.701456310679612 0.1763889197217673 0.5366127906142713 1.8183791501026776 2.572388451454916 0.87346202075329 0.2871327431050578 0.1700164788710275 0.187449079081247 0.3404254693467198 0.0854582473740603 0.1518876235897055 +Ion transport 45 215 1.98944960306415 0.0466515992316742 59.95631067961165 203.33495145631068 1.28794420214731 0.4483240343684334 22.7179419701651 20.293344878478432 1.852388371824549 0.4292871393353351 0.5201640940495685 0.594097712260467 0.0821292627403398 0.0056871319418726 0.003318390819641 +Myeloid cell activation involved in immune response 1 8 1.9795086151731924 0.047758770636952 2.092233009708738 9.5752427184466 0.3896945990003393 0.5451221818031405 1.9697316026512788 2.14785254897903 0.7723774586311952 0.283272731615065 1.0 1.0 0.3209553841799009 0.6257540014635683 0.5817058860938368 +Pinocytosis 3 7 1.976604151647804 0.0480863925117287 1.8713592233009708 7.33252427184466 0.5840579949486326 0.3745201042297812 1.4960968950914608 1.2320991783672317 1.0871891924456092 0.2933375341256155 1.0 1.0 1.0 0.0693365470158766 0.0095480082964634 +Modification of postsynaptic actin cytoskeleton 0 5 1.9720067182031784 0.0486088395958099 1.2718446601941749 4.691747572815534 0.7749873285721138 0.3698922532933065 1.1736936531325053 0.5210425083463128 1.0158209432526408 0.3028676273114866 1.0 1.0 0.0743799864466655 0.1781979724676324 0.3268572232473809 +Cellular sodium ion homeostasis 0 5 1.968007160906453 0.0490672137837377 1.7645631067961165 4.279126213592233 0.3130666300494188 0.4596282540439977 1.2029117398149052 0.6440551245721169 1.0188577401619887 0.3109798964466274 1.0 1.0 0.1094892401774078 0.2550529546148332 0.4477841210026768 +Regulation of synaptic vesicle exocytosis 1 10 1.967044980391476 0.0491780253787914 3.1189320388349513 10.560679611650484 0.4862343841195922 0.5414081938561163 1.8042374139416124 1.5929783804723392 0.7329373521316838 0.2909446135911188 0.1369483172897467 0.151306852499084 0.2802926639431586 0.1988041978590851 0.4934590996900062 +Synaptonemal complex organization 1 7 1.9623288721848693 0.0497242078654835 1.470873786407767 6.174757281553398 0.723394588880887 0.4361908449153728 1.1810092004903878 0.7330900746788283 0.8281604841906476 0.2971095774097388 0.0423440523288004 0.0470522829573702 0.0921025797166938 0.0231366382468947 0.0808987135784085 +Neurotransmitter secretion 2 17 1.9608597804696328 0.049895382169816 4.878640776699029 19.800970873786408 0.4739837619437216 0.5379742436571602 2.5178643472114657 2.5013004441236206 0.8040908235944773 0.3018218439933647 0.2995618964693589 0.3274019772455256 0.5484830827387088 0.5946863363415549 0.7638889101364512 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..04c2df0b6cb1fba70875bce441b54c5587d1f7e5 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 6410, + "title": "Average number of proteins per term", + "value": 18.195319812792512 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7367f3cfb23ea3939b78cf2f08aa5cf22746807e --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e9b78dde25872604811cdac5cea51d6773be3c8b --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1945 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transmembrane transport 0.4690070850212905 3.938896173786305 8.185734138943523e-05 0.4082831396705439 0.002764179069784 224 Q9HD20,Q8IXU6,O60830,Q70HW3,P0CG08,Q99595,P23786,O43772,Q8NHS3,P41440,Q16625,P60602,Q96PU5,P23634,O95831,Q9Y6M7,Q9C0H2,Q9UHG3,P50570,P00846,O95563,Q9Y584,Q8WTV0,Q8TBP6,P38435,P05771,P08183,Q86VD7,P30825,Q15758,Q13423,Q7KZN9,P31751,Q9Y619,P51790,Q96H78,Q9BQT8 37 +Ornithine transport 0.9653833710773216 3.840046132751881 0.0001230111926677 0.5454967643499851 0.0032183744693896 2 P30825 1 +Diacylglycerol biosynthetic process 0.9530896150113252 3.785935675383247 0.0001531312856601 0.6253064186416777 0.0033251828743387 2 Q8NCC3 1 +Phospholipid homeostasis 0.9530896150113252 3.785935675383247 0.0001531312856601 0.6253064186416777 0.0033251828743387 2 Q96CP7 1 +Regulation of response to food 0.9498544160465894 3.771633814076459 0.000162182145047 0.6464293164389043 0.0034196958873405 2 Q9UMX5 1 +Negative regulation of response to food 0.9498544160465894 3.771633814076459 0.000162182145047 0.6464293164389043 0.0034196958873405 2 Q9UMX5 1 +Regulation of appetite 0.9498544160465894 3.771633814076459 0.000162182145047 0.6464293164389043 0.0034196958873405 2 Q9UMX5 1 +Positive regulation of camp dependent protein kinase activity 0.941442898738273 3.7343262521073135 0.0001882183762083 0.7007851334885324 0.0036076446553177 2 Q9Y4G8 1 +Response to cisplatin 0.937884179877065 3.718488557406792 0.0002004183690429 0.7232969860259353 0.0036393250582585 2 P09601 1 +Positive regulation of fatty acid beta oxidation 0.9252669039145934 3.6620764830298937 0.0002501791379947 0.7988790695244365 0.0042201270382797 2 P31751 1 +Positive regulation of fatty acid oxidation 0.9252669039145934 3.6620764830298937 0.0002501791379947 0.7988790695244365 0.0042201270382797 2 P31751 1 +Positive regulation of lipid catabolic process 0.9252669039145934 3.6620764830298937 0.0002501791379947 0.7988790695244365 0.0042201270382797 2 P31751 1 +Protein containing complex remodeling 0.9097379488838604 3.5920809703656458 0.0003280478808287 0.8779264929587185 0.0048439960174255 2 Q8WTV0 1 +Regulation of caveolin mediated endocytosis 0.9013264315755471 3.553902031440064 0.0003795605759147 0.9122659448424388 0.0050252244008177 2 Q96PU5 1 +Rap protein signal transduction 0.9003558718861244 3.5494846668773743 0.0003859859433126 0.915807338485495 0.0050252244008177 2 Q9Y4G8 1 +Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process 0.8980912326108084 3.539167694957471 0.0004013907789732 0.923726628851673 0.0050252244008177 2 P23634 1 +Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway 0.8980912326108084 3.539167694957471 0.0004013907789732 0.923726628851673 0.0050252244008177 2 P23634 1 +Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway 0.8980912326108084 3.539167694957471 0.0004013907789732 0.923726628851673 0.0050252244008177 2 P23634 1 +Positive regulation of cell adhesion molecule production 0.9568113277568336 3.515490628203987 0.000438942251713 0.9400495878449938 0.005410807372078 3 P41440 1 +Cell adhesion molecule production 0.9568113277568336 3.515490628203987 0.000438942251713 0.9400495878449938 0.005410807372078 3 P41440 1 +Response to dietary excess 0.8909737948883898 3.5066533056974216 0.000453779956405 0.9454910124564756 0.0055510105354129 2 Q9BZK7 1 +Regulation of fc gamma receptor signaling pathway involved in phagocytosis 0.8909737948883849 3.5066533056974216 0.000453779956405 0.9454910124564756 0.0055510105354129 2 Q08722 1 +Dendritic cell apoptotic process 0.8864445163377592 3.485891096276094 0.0004905006456832 0.9569279284957604 0.0057374254358229 2 Q9Y4G8 1 +Regulation of b cell receptor signaling pathway 0.8864445163377574 3.485891096276094 0.0004905006456832 0.9569279284957604 0.0057374254358229 2 P05771 1 +Negative regulation of toll like receptor signaling pathway 0.8864445163377612 3.485891096276094 0.0004905006456832 0.9569279284957604 0.0057374254358229 2 Q9NPR9 1 +Positive regulation of fc receptor mediated stimulatory signaling pathway 0.8864445163377541 3.485891096275973 0.0004905006456834 0.9569279284958216 0.0057374254358229 2 Q06481 1 +Peripheral nervous system axon regeneration 0.8767389194435481 3.4412123138264903 0.000579113930291 0.9756005717324212 0.0065239372463372 2 Q96G23 1 +Negative regulation of muscle organ development 0.9354847965508978 3.423424375881687 0.0006183745520469 0.981032094924773 0.0065953092822311 3 P16989 1 +Negative regulation of muscle tissue development 0.9354847965508978 3.423424375881687 0.0006183745520469 0.981032094924773 0.0065953092822311 3 P16989 1 +Negative regulation of fatty acid transport 0.8670333225493434 3.3962739919115332 0.0006830994375028 0.9874766904654898 0.0070503605930063 2 P31751 1 +Cenp a containing chromatin organization 0.8631510837916572 3.378225246664623 0.0007295529580086 0.9907037217236804 0.0074229118425964 2 Q6IPU0 1 +Ovulation cycle process 0.859268845033976 3.360134228071894 0.0007790461257046 0.9932325561420082 0.0077421483190185 2 O94813 1 +Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress 0.856357165965715 3.34653809304833 0.0008182743577673 0.9947382193657588 0.0079471797474074 2 P16989 1 +Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress 0.856357165965715 3.34653809304833 0.0008182743577673 0.9947382193657588 0.0079471797474074 2 P16989 1 +Intrinsic apoptotic signaling pathway in response to osmotic stress 0.856357165965715 3.34653809304833 0.0008182743577673 0.9947382193657588 0.0079471797474074 2 P16989 1 +Cellular response to muramyl dipeptide 0.8563571659657121 3.34653809304833 0.0008182743577673 0.9947382193657588 0.0079471797474074 2 P08670 1 +Negative regulation of cell volume 0.8534454868974516 3.3329179676526293 0.0008594027732542 0.9959585036039064 0.0082165114447889 2 P51790 1 +Regulation of membrane invagination 0.8534454868974457 3.3329179676525573 0.0008594027732544 0.9959585036039122 0.0082165114447889 2 Q06481 1 +Purinergic nucleotide receptor signaling pathway 0.8534454868974464 3.3329179676525573 0.0008594027732544 0.9959585036039122 0.0082165114447889 2 P04899 1 +Cell motility involved in cerebral cortex radial glia guided migration 0.8521514073115484 3.3268568541931467 0.0008783147952824 0.9964202837505584 0.0083160972492769 2 Q8WXH0 1 +Collateral sprouting 0.8502102879327067 3.317756247515145 0.0009074363681498 0.9970303401018472 0.0085163501022553 2 Q8N0X7 1 +Negative regulation of collateral sprouting 0.8502102879327067 3.317756247515145 0.0009074363681498 0.9970303401018472 0.0085163501022553 2 Q8N0X7 1 +Regulation of collateral sprouting 0.8502102879327067 3.317756247515145 0.0009074363681498 0.9970303401018472 0.0085163501022553 2 Q8N0X7 1 +Xenobiotic transport across blood brain barrier 0.8456810093820851 3.2964796549514763 0.0009790470539186 0.9981242856790516 0.0089796418825075 2 P08183 1 +Sphingolipid translocation 0.8456810093820851 3.2964796549514763 0.0009790470539186 0.9981242856790516 0.0089796418825075 2 P08183 1 +Protein targeting to mitochondrion 0.6178251903034162 3.275322994253448 0.0010554122969823 0.9988508874973794 0.0094658171189472 48 Q8N4H5,Q9P0J0,O95429,O60830,Q9NS69,O43464,Q5JRX3,P60602,P51572,Q99595,Q9Y584,P55786,P62072,Q10713,O95831,O95817 16 +Adenylate cyclase activating adrenergic receptor signaling pathway 0.8983818770226469 3.2606044594406836 0.0011117500797674 0.9991995066173508 0.0096171633081101 3 Q9Y4G8,P23634 2 +Adrenergic receptor signaling pathway 0.8983818770226469 3.2606044594406836 0.0011117500797674 0.9991995066173508 0.0096171633081101 3 Q9Y4G8,P23634 2 +Regulation of clathrin dependent endocytosis 0.8976250646845567 3.2572474810983305 0.0011249830369002 0.9992646768658088 0.0096664092044644 3 P50570 1 +Modulation of excitatory postsynaptic potential 0.8964769239996409 3.252151916665005 0.0011453478727796 0.999354759515396 0.0098019757870728 3 Q9UQB8 1 +Detection of external biotic stimulus 0.835975412487877 3.250688315916477 0.0011512599548169 0.999378781371265 0.0098132663701832 2 Q8WTV0 1 +Negative regulation of natural killer cell mediated immunity 0.8359754124878702 3.250688315916422 0.0011512599548171 0.999378781371266 0.0098132663701832 2 P46108 1 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.8359754124878688 3.250688315916422 0.0011512599548171 0.999378781371266 0.0098132663701832 2 P10321 1 +Nucleotide binding domain leucine rich repeat containing receptor signaling pathway 0.8934722906174715 3.2388011693133785 0.0012003321950002 0.9995466068028602 0.0101505664511236 3 Q96RT1 1 +Macropinocytosis 0.8912621359223241 3.2289658919479725 0.0012423871138198 0.9996538548979732 0.0104510517054924 3 Q9BZG1,P50570 2 +Organic acid transmembrane transport 0.6955449945127757 3.2265589007305424 0.0012528844199621 0.9996764070918892 0.0105117658795256 34 P30825,Q15758,P41440,O95563,P31751,Q9Y619,P23786,O43772,Q9BQT8,P08183 10 +Lens fiber cell development 0.8298285344548761 3.2215458060318123 0.001275010796462 0.9997192466001809 0.0106586410670004 2 P08670 1 +Lens fiber cell differentiation 0.8298285344548761 3.2215458060318123 0.001275010796462 0.9997192466001809 0.0106586410670004 2 P08670 1 +Regulation of histone h3 k14 acetylation 0.8265933354901407 3.20616326178165 0.0013451764407099 0.9998210466923836 0.0111546972638433 2 Q03164 1 +Phagocytosis recognition 0.8820641085260763 3.187899648813857 0.0014331026324425 0.9998982281021538 0.0115549533005746 3 Q5KU26 1 +Response to acetylcholine 0.8790717220166446 3.1744925280434275 0.0015009875525542 0.9999341781161726 0.0120417149084764 3 P23634 1 +Mitochondrial transport 0.524096742500224 3.1726277781927945 0.0015106606650954 0.9999381412101894 0.0120861744814948 88 Q9P0J0,O95429,O60830,Q9NS69,Q5JRX3,Q99595,P23786,O43772,P55786,Q9UJZ1,Q9Y3D6,Q8N4H5,P60602,O95831,O95817,P00846,O43464,Q9Y584,Q13794,P50416,P51572,P62072,Q10713 23 +Negative regulation of synapse organization 0.817858298285345 3.16447633447169 0.0015536229631549 0.999953051873924 0.0123099174212897 2 Q15375 1 +Positive regulation of histone h3 k9 acetylation 0.8175347783888711 3.1629280339669745 0.0015619093742182 0.999955484184723 0.012360295171283 2 Q12824 1 +Negative regulation of protein targeting to mitochondrion 0.8755993169553755 3.1589055806708637 0.0015836278745207 0.9999612779331738 0.0125167135335114 3 O95429 1 +Regulation of adherens junction organization 0.8146230993206132 3.1489793089200613 0.0016384179537025 0.9999727613064128 0.0126358558450581 2 P35241 1 +Regulation of mast cell activation involved in immune response 0.8732343104624603 3.1482715428542547 0.0016423904767481 0.9999734472635976 0.0126358558450581 3 P09601 1 +Diacylglycerol metabolic process 0.926162140986092 3.1193240799023627 0.0018126646752163 0.999991102357024 0.0136375358780948 4 Q8NCC3 1 +Protein targeting 0.4844426896098421 3.0975561078154463 0.0019512345560501 0.9999963457944548 0.0145097604458023 107 P46379,Q9P0J0,O95429,O60830,Q9NS69,Q5JRX3,Q99595,P55786,Q14108,Q9Y3D6,Q8N4H5,Q5BJH7,P60602,P43307,O43681,O95831,O95817,O43464,Q9Y584,P27105,Q96RL7,P31751,P51572,P20645,O60725,P62072,Q10713,Q96RT1 28 +Folic acid containing compound catabolic process 0.802976383047562 3.0929304809418423 0.0019819055673857 0.9999969991663484 0.0147207586175465 2 Q9NRN7 1 +Negative regulation of lipid transport 0.8605682252166746 3.091069826490761 0.0019943672801778 0.9999972299886238 0.0147620026165591 3 P31751 1 +Regulation of triglyceride metabolic process 0.9191954234511448 3.0896448824705978 0.0020039594093987 0.9999973954948048 0.0148102498875279 4 Q8WTV0 1 +Xenobiotic export 0.8010352636687266 3.083549241337506 0.002045472564361 0.9999980050808546 0.0149503752993778 2 P08183 1 +Positive regulation of glucose import 0.8581199754034162 3.079964328262133 0.0020702538873242 0.9999982986404298 0.0150628007011903 3 Q16625 1 +Regulation of dna primase activity 0.8575085642516547 3.0771884223107784 0.0020896316772662 0.9999984977602614 0.0151263600715259 3 Q9BRX5 1 +Toll like receptor 3 signaling pathway 0.91624077650612 3.077023436646299 0.0020907886151906 0.9999985088827844 0.0151263600715259 4 P41440 1 +Response to muramyl dipeptide 0.8566343042071072 3.07321741123236 0.0021176414572727 0.9999987451249888 0.0152197199393672 3 Q96RT1,P08670 2 +Regulation of axon guidance 0.798447104496937 3.071023130398472 0.002133266243194 0.99999886496014 0.0152274349876104 2 O94813 1 +Regulation of cell adhesion mediated by integrin 0.8559516757262973 3.070115402014157 0.0021397607474817 0.9999989113386047 0.0152568035498979 3 P07948 1 +Protein localization to mitochondrion 0.5396226982420564 3.043749804262084 0.0023364936892475 0.9999996923947694 0.0162969799217378 61 Q8N4H5,Q9P0J0,O95429,O60830,Q9NS69,O43464,Q5JRX3,P60602,P51572,Q99595,Q9Y584,P55786,P62072,Q10713,O95831,O95817 16 +Mitochondrial transmembrane transport 0.5441612598318615 3.0270364105900427 0.0024696420868692 0.999999869250916 0.0168947767095326 57 P00846,O60830,O95563,P60602,Q9Y619,Q99595,P23786,O43772,O95831 9 +Neuroepithelial cell differentiation 0.8419051864136817 3.006008011488845 0.0026470202352562 0.9999999581802006 0.0179170007476159 3 P07437 1 +Positive regulation of cholesterol storage 0.8392707445727431 2.9939253201508715 0.0027541334707616 0.9999999789917582 0.0184665225393122 3 Q8WTV0 1 +Manganese ion transport 0.836361751712603 2.98056152250882 0.0028772043742391 0.9999999904761152 0.0191713929718011 3 Q9HD20 1 +Manganese ion transmembrane transport 0.836361751712603 2.98056152250882 0.0028772043742391 0.9999999904761152 0.0191713929718011 3 Q9HD20 1 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.8362459546925343 2.9800290790251136 0.0028822102153793 0.999999990777716 0.0191848052757858 3 Q03518,Q9UIQ6 2 +Myelin assembly 0.8915697280132775 2.970829850534327 0.002969962771181 0.999999994753936 0.0197202227415352 4 Q9NR77 1 +Sterol import 0.831176116021912 2.956681701111942 0.003109689493097 0.9999999978636496 0.0202572252548296 3 Q8WTV0 1 +G protein coupled receptor signaling pathway involved in heart process 0.8303216305545771 2.952739742937435 0.0031496738701612 0.9999999983479873 0.0204346250078278 3 P23634 1 +Pointed end actin filament capping 0.7719184729860902 2.9414435221679227 0.0032668640948898 0.9999999992224542 0.0210461700501588 2 P28289 1 +Regulation of long term synaptic depression 0.767065674538987 2.9175027928782726 0.0035284648883495 0.9999999998554588 0.0221957408580183 2 Q9NUL3 1 +Excretion 0.8756879248948017 2.901695922349447 0.0037114861127192 0.9999999999554712 0.0230752919326189 4 P04899,Q96PU5,P09601 3 +Regulation of histone h4 k16 acetylation 0.8177993527508056 2.8947407395289586 0.0037947180558004 0.9999999999739346 0.023355544465293 3 O75844,Q12824 2 +Regulation of fertilization 0.7618893561954054 2.891884044079015 0.0038293925248613 0.999999999979147 0.023444513929667 2 P35579 1 +Response to l glutamate 0.9098234845786732 2.840609275128661 0.004502744337381 0.9999999999997266 0.0260481939181054 5 Q9UQB8 1 +Negative regulation of lymphocyte mediated immunity 0.8055915855237246 2.83777923212541 0.0045428591711293 0.9999999999997888 0.0261868051141541 3 P46108 1 +Endocytosis 0.4804457801793854 2.8325006467165013 0.0046185472754793 0.9999999999998704 0.0263542510931641 96 Q13614,Q5VW38,P61978,P11717,O15118,Q14108,P50897,Q8NC96,P02786,P84095,P41440,Q13432,Q96PU5,Q9NX40,Q5KU26,P50570,Q06481,Q8WTV0,Q9UBG0,O15126,Q9BZG1,Q14C86,P51790,Q05086 24 +L serine transport 0.7499191200258931 2.832313977693419 0.0046212446534659 0.9999999999998724 0.0263542510931641 2 Q15758 1 +Immune response regulating signaling pathway 0.5712206023514157 2.831829318236985 0.0046282546716782 0.999999999999878 0.0263707666181846 46 P07948,Q96J02,P46379,Q08722,P41440,Q96RT1,Q06481,Q9NPR9,Q9UJZ1,P05771,Q5KU26 11 +Protein localization to axon 0.7483015205435123 2.824228745486234 0.0047394546596759 0.9999999999999404 0.0267048296215235 2 Q12955 1 +Toll like receptor 4 signaling pathway 0.8576328109692354 2.822352280188321 0.004767277857743 0.9999999999999504 0.0267117579266893 4 P41440,Q06481 2 +Regulation of toll like receptor 4 signaling pathway 0.8576328109692354 2.822352280188321 0.004767277857743 0.9999999999999504 0.0267117579266893 4 P41440,Q06481 2 +Regulation of transforming growth factor beta1 production 0.7476544807505705 2.8209922925907165 0.0047875353111894 0.9999999999999564 0.0267784479447858 2 O75787 1 +Transforming growth factor beta1 production 0.7476544807505705 2.8209922925907165 0.0047875353111894 0.9999999999999564 0.0267784479447858 2 O75787 1 +Bleb assembly 0.800264012540219 2.8127897132730766 0.0049113758254144 0.9999999999999803 0.0273280547230092 3 Q9NR77 1 +Positive regulation of torc1 signaling 0.7977346278317151 2.8008973218896007 0.0050960730774423 0.999999999999994 0.028208832838001 3 Q96EE3,Q9P2J5 2 +Alpha beta t cell proliferation 0.7967690671874462 2.796352774160719 0.005168295238535 0.9999999999999962 0.028436714574257 3 Q96J02 1 +Negative regulation of glucose transmembrane transport 0.7947456169024126 2.786820541630541 0.0053227946926994 0.9999999999999986 0.0291865816768208 3 P05771 1 +Tetrapyrrole catabolic process 0.8462285529297717 2.7718193749950686 0.0055743958781171 0.9999999999999998 0.030332663479398 4 P53004,P09601,P30519 3 +Protein transmembrane transport 0.6642706378041923 2.767822840803733 0.005643212231764 0.9999999999999998 0.0305773376209698 27 O60830,P60602,Q99595,Q9Y584,O95831 5 +Negative regulation of calcium ion import 0.7350372047881022 2.7576105359805823 0.0058225523932622 1.0 0.0312322684860402 2 P21796 1 +Negative regulation of interleukin 2 production 0.7350372047880919 2.75761053598052 0.0058225523932633 1.0 0.0312322684860402 2 P15311 1 +Positive regulation of er associated ubiquitin dependent protein catabolic process 0.734390164995156 2.7543462307812168 0.0058809517787448 1.0 0.0314665282986262 2 P51572 1 +Bicarbonate transport 0.7839211103369144 2.7356295051947552 0.0062261081805898 1.0 0.0329829367252736 3 Q9Y6M7 1 +Mitochondrion organization 0.4069088480272118 2.7184673005397917 0.0065585138058925 1.0 0.0345156596845413 192 Q9P0J0,Q9UDX5,O95429,O60830,Q9NS69,Q9BQP7,Q5JRX3,P21796,Q99595,Q69YU5,P55786,P03886,P14406,O75153,Q9UJZ1,O96000,P02786,Q9Y3D6,Q8N4H5,Q9H061,Q6DKK2,P60602,Q13505,Q96TA2,Q5XKP0,Q9Y375,O95831,O95817,O43464,Q9Y5P4,P51970,Q9NX63,Q96CU9,Q9Y584,Q13794,Q96RL7,Q8N163,O43819,P60520,P51572,P62072,Q10713 42 +Anion transmembrane transport 0.5428281237434307 2.6912258015059245 0.0071189992601441 1.0 0.0365062282060191 49 Q8TDW0,P30825,Q15758,Q9UHG3,Q4KMQ2,P41440,O95563,Q9Y619,P51790,P21796,P45880,Q9BQT8,P08183,Q9Y6M7,P33527,Q86VD7 16 +Circulatory system process 0.5005688304767074 2.689455200653607 0.0071568752610056 1.0 0.0366711194428824 66 P42785,O94813,Q9NZ08,P42892,P02786,P41440,Q16625,Q96PU5,P23634,P04899,Q9UIQ6,P09601,Q99808,P08183,P33527,O95319,P28161,P30825,O75844,Q15758,Q9HB40 21 +Intracellular protein transmembrane transport 0.6675265421172912 2.684102538022401 0.0072724797894725 1.0 0.037131446539585 23 O60830,Q99595,O95831,P60602 4 +Positive regulation of glucose transmembrane transport 0.8265439931156584 2.6838261900390927 0.0072784934713974 1.0 0.037131446539585 4 Q16625 1 +Regulation of transport 0.3462424196364666 2.683689444672224 0.0072814708736752 1.0 0.037131446539585 295 Q13614,Q9BZF3,Q00765,O95429,Q32P28,P61978,Q4J6C6,P0CG08,P21796,P55786,P50897,Q08J23,Q03164,Q9Y3D6,O00459,P41440,Q16625,Q13555,Q6IQ22,Q13432,Q96PU5,P35241,P23634,P04899,O95817,Q9BRK0,Q6IAA8,P50570,Q08722,O95563,O43464,Q4KMQ2,P09601,Q6WKZ4,Q9Y2G5,Q06481,Q9P2W9,P27105,Q8WTV0,P53367,P05771,P35580,P08183,P28161,P07948,O95071,O75844,P50416,Q14C86,P31751,P51572,Q9ULX6,Q9Y282,P52298,Q16850 55 +Regulation of hippo signaling 0.7198317696538319 2.680536073355731 0.0073504341548613 1.0 0.037393875343382 2 Q01085 1 +Regulation of glial cell proliferation 0.7722328057528802 2.6799758748324285 0.0073627466413814 1.0 0.037397152116684 3 Q96G23 1 +Negative regulation of cell killing 0.7719635073979583 2.6786889654933295 0.0073911014526772 1.0 0.0375007165552957 3 P46108 1 +Negative regulation of leukocyte mediated immunity 0.8249913313974442 2.6768436893501923 0.0074319298350933 1.0 0.0375007165552957 4 P46108,P09601 2 +Positive regulation of activated t cell proliferation 0.7695802677136669 2.667290894363252 0.0076465455908223 1.0 0.0380841936574756 3 Q9HCL2 1 +Glyoxylate metabolic process 0.7692556634303891 2.6657371679177313 0.0076819725187105 1.0 0.0381931147239812 3 P48735,Q9UBQ7 2 +Meiotic sister chromatid cohesion centromeric 0.7130378518278899 2.6458516462437305 0.0081485544359367 1.0 0.0397203299881024 2 O60566 1 +Intestinal epithelial cell differentiation 0.7114202523455222 2.6375708151008013 0.0083502188981305 1.0 0.0402140519436642 2 Q9NQ88 1 +Intestinal epithelial cell development 0.7114202523455222 2.6375708151008013 0.0083502188981305 1.0 0.0402140519436642 2 Q9NQ88 1 +Phosphatidylcholine catabolic process 0.815894484416583 2.635810190830811 0.008393666894445 1.0 0.0403626442561088 4 Q8NCC3 1 +Inositol phosphate catabolic process 0.7615790607484553 2.628903542971687 0.0085660654154728 1.0 0.0409005882973422 3 Q13614 1 +Gamma aminobutyric acid signaling pathway 0.7085085732772682 2.6226433114367915 0.0087250564282612 1.0 0.0414585705746143 2 P04899 1 +Tolerance induction 0.7601825605683358 2.622184419262011 0.0087368139916652 1.0 0.0414836871752402 3 Q96J02 1 +Base excision repair ap site formation 0.7072144936913679 2.615999768394473 0.0088966617933587 1.0 0.0421375504627493 2 P29372 1 +Acute inflammatory response 0.8114842475320481 2.6158402896048636 0.0089008179916634 1.0 0.0421375504627493 4 P42785,P02786 2 +Membrane depolarization during action potential 0.7065674538984164 2.6126758948276936 0.0089836451070153 1.0 0.0423890696451963 2 Q12955 1 +Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway 0.7562854069781728 2.6034034560471024 0.0092303260233237 1.0 0.0433771186286695 3 P23634 1 +Regulation of interleukin 1 mediated signaling pathway 0.7033322549336776 2.5960354777636137 0.0094306327149447 1.0 0.0441888565078915 2 Q86Y07 1 +Interleukin 1 mediated signaling pathway 0.7033322549336776 2.5960354777636137 0.0094306327149447 1.0 0.0441888565078915 2 Q86Y07 1 +Synaptic transmission gabaergic 0.8068192834548403 2.5946623819412635 0.0094683875767873 1.0 0.0442518650575236 4 Q13641 1 +Regulation of blood pressure 0.7290777095152249 2.5945423624524526 0.0094716940497538 1.0 0.0442518650575236 17 P42785,Q9HB40,Q9UIQ6,P09601,P42892 5 +Megakaryocyte development 0.7000970559689446 2.5793599139588186 0.0098983596450323 1.0 0.0457121652194939 2 Q8IZP0 1 +Phagosome lysosome fusion 0.750248902959457 2.57422465052839 0.0100465017576509 1.0 0.0460644322364397 3 Q9BZG1 1 +Serine transport 0.7501618122977244 2.5738028937074633 0.0100587559012617 1.0 0.0460868706749889 3 Q96NB2,Q15758 2 +Regulation of immune response 0.450855366398314 2.5676010255637753 0.0102404944651464 1.0 0.0463897687058207 101 P46379,P12956,Q9NZ08,Q9Y3Z3,Q9NQT5,Q9UJZ1,P02786,P23396,P41440,P28070,Q9NPR9,Q5KU26,Q96J02,Q08722,P09601,Q06481,P05771,P07948,Q14166,P46108,P04439,O15400,O96028,Q96RT1 24 +Negative regulation of establishment of protein localization to mitochondrion 0.8005404873214044 2.5660691411352565 0.0102858323018142 1.0 0.0463897687058207 4 O95429 1 +Guanine nucleotide transport 0.748527306335427 2.5658832714075217 0.0102913454606461 1.0 0.0463897687058207 3 P41440 1 +Guanine nucleotide transmembrane transport 0.748527306335427 2.5658832714075217 0.0102913454606461 1.0 0.0463897687058207 3 P41440 1 +Cyclic gmp amp transmembrane import across plasma membrane 0.748527306335427 2.5658832714075217 0.0102913454606461 1.0 0.0463897687058207 3 P41440 1 +Magnesium ion homeostasis 0.7475728155339793 2.561254862573004 0.0104294814823051 1.0 0.0469143693344393 3 Q12955,Q6P4Q7 2 +Sphingolipid mediated signaling pathway 0.6952442575218374 2.5542804806862196 0.0106407502562997 1.0 0.0477307271818623 2 P15311 1 +Inorganic anion transport 0.6223098900717319 2.5515179864623407 0.0107254787886217 1.0 0.0480771461783673 29 Q9C0H2,Q8TDW0,Q9UHG3,Q4KMQ2,P51790,P21796,P0CG08,P45880,O43681,Q9Y6M7,P08183 11 +Collagen biosynthetic process 0.7951523947314254 2.5414505058696166 0.0110393574762193 1.0 0.049226887312061 4 Q92791 1 +Regulated exocytosis 0.6057391752361653 2.534904994944932 0.0112477826201935 1.0 0.0498950080245264 32 O43760,P09601,Q4J6C6,Q6WKZ4,P05771,Q9BRK5,P04899 7 +Caveolin mediated endocytosis 0.7419429006415926 2.5339001640088195 0.0112800864321873 1.0 0.050003702648908 3 Q96PU5 1 +Intracellular mrna localization 0.690391459074736 2.5291214961326083 0.0114348436189772 1.0 0.0506546977177915 2 Q99729 1 +Mitotic dna replication checkpoint signaling 0.7375404530743973 2.512444113776331 0.0119898093980936 1.0 0.0521021851453881 3 Q13564,Q9Y619 2 +Nucleotide sugar transmembrane transport 0.686832740213529 2.510620862146357 0.0120519058256092 1.0 0.0521021851453881 2 Q9Y2D2 1 +Purine nucleoside biosynthetic process 0.8324511075236293 2.5088674387678784 0.0121118927641818 1.0 0.0521021851453881 5 P55263 1 +Purine ribonucleoside salvage 0.8324511075236293 2.5088674387678784 0.0121118927641818 1.0 0.0521021851453881 5 P55263 1 +Nucleoside salvage 0.8324511075236293 2.5088674387678784 0.0121118927641818 1.0 0.0521021851453881 5 P55263 1 +Response to thyroglobulin triiodothyronine 0.6845681009382087 2.498825338343794 0.0124605708114571 1.0 0.0521021851453881 2 P11166 1 +Inositol phosphate metabolic process 0.8293943263066825 2.495475335353695 0.0125788499853463 1.0 0.0522556243720478 5 Q13614,Q9UNW1 2 +Regulation of mitochondrial atp synthesis coupled electron transport 0.7324935916051271 2.487776596319734 0.012854445252272 1.0 0.0532327842255963 3 P14635 1 +Nerve development 0.8716323871069065 2.483844975131483 0.0129972376038121 1.0 0.0536115141830345 6 P42892 1 +Establishment of protein localization to membrane 0.4625053686856409 2.4827509363842744 0.0130372206667053 1.0 0.0537418549669331 87 Q9HD20,Q5BJH7,P46379,Q9BRK0,Q9BZG1,Q9P0J0,Q9NS69,P31751,P60602,Q4J6C6,O60725,O15118,Q9Y584,P62072,P43307,P27105,Q9NPA0,Q9Y3D6 18 +Progesterone receptor signaling pathway 0.7823133562442356 2.4824826602261383 0.0130470417601999 1.0 0.053747774860464 4 Q05086,O95071 2 +Regulation of mast cell activation 0.7797931882654188 2.4708572207935635 0.0134789622805622 1.0 0.0552256086301529 4 P09601 1 +Protein localization to membrane raft 0.8237620030880195 2.4707416327106273 0.0134833194237424 1.0 0.0552256086301529 5 P41440 1 +Regulation of fc receptor mediated stimulatory signaling pathway 0.7795688691580327 2.4698216372471213 0.0135180434514441 1.0 0.055322890649056 4 Q06481,Q08722 2 +Plasma membrane organization 0.6512246256552113 2.46965524241016 0.0135243322382325 1.0 0.055322890649056 21 P41440,P31751,Q96CP7,Q9UQB8 4 +Fatty acid transmembrane transport 0.8432675184570476 2.464002810314058 0.0137395034156577 1.0 0.0559886947834496 8 P23786,P31751,O43772 3 +Walking behavior 0.7779199488776327 2.462205234366607 0.0138085625362229 1.0 0.0561629986403485 4 O43464,O15118 2 +Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.7263020961937323 2.457410844649314 0.0139942541659994 1.0 0.0568101134921192 3 P11940 1 +Protein trimerization 0.7762672872839667 2.4545643804700155 0.0141055404074421 1.0 0.0571894459277066 4 Q99720 1 +Positive regulation of endothelial cell development 0.6751860239404791 2.449772063192804 0.0142946673224821 1.0 0.0575986619249213 2 P35611 1 +Positive regulation of homotypic cell cell adhesion 0.675186023940476 2.4497720631927873 0.0142946673224828 1.0 0.0575986619249213 2 Q12955 1 +Positive regulation of rho protein signal transduction 0.6751860239404727 2.4497720631927704 0.0142946673224835 1.0 0.0575986619249213 2 P63000 1 +Lipoprotein localization 0.8623887127364469 2.4450093039456067 0.0144848405227893 1.0 0.0581960549386147 6 P04114,A6NIH7,P05771 3 +Positive regulation of syncytium formation by plasma membrane fusion 0.7734721023700808 2.4416248760521526 0.0146213306081013 1.0 0.0584670799737551 4 P41440 1 +Regulation of myoblast fusion 0.7734721023700808 2.4416248760521526 0.0146213306081013 1.0 0.0584670799737551 4 P41440 1 +Regulation of syncytium formation by plasma membrane fusion 0.7734721023700808 2.4416248760521526 0.0146213306081013 1.0 0.0584670799737551 4 P41440 1 +Positive regulation of myoblast fusion 0.7734721023700808 2.4416248760521526 0.0146213306081013 1.0 0.0584670799737551 4 P41440 1 +Modulation by host of symbiont catalytic activity 0.6735684244581114 2.441284223279268 0.0146351313480399 1.0 0.0584857805118055 2 Q9H1E3 1 +Protein transmembrane import into intracellular organelle 0.7375877665798406 2.4357256183807725 0.0148619530668183 1.0 0.0592813435957098 14 O60830,Q99595,P60602 3 +Regulation of tooth mineralization 0.6716273050792692 2.4310869952573393 0.0150535996173974 1.0 0.0598886487985316 2 Q6W2J9 1 +Organic acid transport 0.5084407205957541 2.424007241719468 0.0153502993822902 1.0 0.0607004435783347 50 P30825,Q15758,P41440,O95563,P31751,Q9Y619,P23786,O43772,Q96H78,Q9BQT8,P08183 11 +Negative regulation of fatty acid biosynthetic process 0.7687551274833204 2.4197423375503484 0.0155315079321323 1.0 0.061265825135365 4 P49748 1 +Transcription initiation from rna polymerase iii promoter 0.7182084719637908 2.41754352458088 0.0156256651339081 1.0 0.0613221083598128 3 Q9Y5Q8 1 +Negative regulation of blood pressure 0.7681162170550035 2.4167738547465647 0.0156587422715372 1.0 0.0613221083598128 4 P42785 1 +Nitrogen compound transport 0.3252726356366745 2.4160208053780545 0.0156911647357163 1.0 0.061366910284284 561 P46379,Q96PC5,Q8NBM4,O60830,O60831,Q4J6C6,Q99595,O75396,P36405,O43772,P55786,P50402,P40616,Q15388,Q8N4H5,Q9UI26,P41440,Q9BXS5,Q8WWC4,Q7Z434,P60602,Q16836,O60749,O95831,P30040,Q9Y2D2,Q9NVJ2,Q9BRK0,O95563,O43615,O94979,O15127,Q9Y584,P53367,P08183,Q86VD7,P30825,Q8N183,P31751,Q92538,Q9Y619,Q8N1F7,O60725,P37108,A6NIH7,P62072,Q96H78,P35579,Q16850,P06493,Q96RT1,O43731,Q9HD20,Q96FZ7,Q9UBU9,Q32P28,Q6NUQ1,P0CG08,O00429,O15027,P20338,Q8NC96,Q08J23,Q86V81,O14653,Q5BJH7,Q96CS3,P67809,P24390,Q6P6C2,Q12955,O15173,Q13555,Q6IQ22,O00410,O60826,O75298,O43865,P09132,Q16629,O00400,Q8N6T3,Q99496,Q15717,Q7Z3B4,P50570,Q14746,Q9Y5P4,O75746,Q6WKZ4,Q06787,Q13277,Q8N2H4,Q96EE3,Q9Y2V7,Q96DA6,Q96DZ1,P05771,Q96RL7,Q9BZG1,Q15758,P50416,Q14C86,Q9ULX6,Q9Y282,P52298,Q10713,Q9P0J0,O95429,Q9NS69,Q14108,P50897,P04114,P02786,Q13432,P43307,O95817,Q9Y3Y2,Q08722,O43464,Q06481,P27105,O43823,O15126,P07948,P83436,Q03518,Q9H814,P60520,P51572,P20645,O15400,P57740,Q9H267,Q96P70,Q8TDW0,Q86U42,Q5JRX3,Q6P4A7,Q9Y3D6,O00459,P51991,P49321,Q9Y2D4,Q96AX1,O43681,Q13190,Q92974,O00148,O75381,Q9UP83,Q9P2W9,Q99808,Q99567,P35580,P33527,O95071,O15504,Q9NRW7,Q9Y2T2,O60499 161 +Positive regulation of ligase activity 0.6683921061145333 2.4140629301601124 0.0157757373832698 1.0 0.0616224720455575 2 P18887 1 +Copper ion import 0.6677450663215848 2.4106538106802744 0.0159239553364973 1.0 0.0618621537617919 2 P35670 1 +Response to cobalt ion 0.6677450663215846 2.4106538106802744 0.0159239553364973 1.0 0.0618621537617919 2 Q9NQ88 1 +Copper ion transmembrane transport 0.6677450663215848 2.4106538106802744 0.0159239553364973 1.0 0.0618621537617919 2 P35670 1 +Positive regulation of secondary metabolite biosynthetic process 0.6677450663215809 2.4106538106802593 0.015923955336498 1.0 0.0618621537617919 2 O60315 1 +Regulation of iron ion transmembrane transport 0.6677450663215805 2.4106538106802544 0.0159239553364982 1.0 0.0618621537617919 2 Q9H1K1 1 +Regulation of iron ion transport 0.6677450663215805 2.4106538106802544 0.0159239553364982 1.0 0.0618621537617919 2 Q9H1K1 1 +Serotonin metabolic process 0.6677450663215789 2.410653810680244 0.0159239553364987 1.0 0.0618621537617919 2 P05091 1 +Positive regulation of pinocytosis 0.7666540566728832 2.409976364548511 0.0159535540047193 1.0 0.0619021072459145 4 P50897 1 +Regulation of pinocytosis 0.7666540566728832 2.409976364548511 0.0159535540047193 1.0 0.0619021072459145 4 P50897 1 +Pattern recognition receptor signaling pathway 0.615512465295214 2.3996359078571587 0.0164113863208048 1.0 0.0632863610062382 25 Q96J02,P41440,Q06481,Q9NPR9,Q96RT1,Q5KU26 6 +Macromolecule depalmitoylation 0.8075745370147015 2.399237198024822 0.0164292683223754 1.0 0.063288227131266 5 Q9UMR5 1 +Protein mannosylation 0.7127450943403337 2.390521234134109 0.0168244762240923 1.0 0.0643304494897886 3 O60762 1 +Protein o linked mannosylation 0.7127450943403337 2.390521234134109 0.0168244762240923 1.0 0.0643304494897886 3 O60762 1 +Retinal ganglion cell axon guidance 0.7623032626224415 2.3897164119013516 0.0168613867293048 1.0 0.0644108992460333 4 O94813 1 +Regulation of response to extracellular stimulus 0.8044761260946072 2.385479570464748 0.0170568697267112 1.0 0.064964073053012 5 Q9UMX5 1 +Dna replication checkpoint signaling 0.7607998926565618 2.3827041758219827 0.0171859986551534 1.0 0.0653006825012055 4 Q9UNS1,Q9Y619 2 +Vesicle mediated transport 0.3344868422330256 2.3766360878043717 0.0174713153229943 1.0 0.0662335315858676 323 Q96PC5,Q5VW38,Q4J6C6,O75396,P36405,Q92734,P40616,P41440,Q9BXS5,P62993,Q96PU5,O60749,Q5KU26,Q9NVJ2,Q9H5V9,P09601,O94979,O15127,Q8WTV0,P53367,O43760,O60664,P31751,Q92538,P51790,Q05086,P35579,O43731,Q13614,Q96FZ7,Q8WU17,Q6NUQ1,Q14203,O15118,O00429,O15027,P20338,Q8NC96,O14653,Q5BJH7,P24390,Q12955,Q6IQ22,O60826,Q8N6T3,Q8TBA6,Q9NX40,P50570,Q14746,O75503,Q6WKZ4,P54652,Q06787,Q13277,Q8N2H4,Q9Y2V7,Q9BRK5,P05771,Q96RL7,Q9BZG1,Q14C86,Q9Y282,Q8NHH9,P61978,P11717,Q14108,P50897,P02786,P84095,Q13432,P35241,P04899,Q08722,Q12981,Q06481,Q9UBG0,O15126,P07948,P83436,P60520,P51572,P20645,O15400,Q9H267,Q9Y2D4,Q96AX1,Q13190,Q6IAA8,Q4KMQ2,Q9UP83,Q9P2W9,Q96D71,Q9NRW7,Q9Y2T2,O60499 95 +Positive regulation of antigen receptor mediated signaling pathway 0.7096718569436633 2.375281380788236 0.0175355767483622 1.0 0.0663046163239864 3 P05771 1 +Mitochondrial respiratory chain complex assembly 0.5282640997750868 2.371794497060759 0.0177019333226597 1.0 0.0667467015283819 42 Q9P0J0,O43819,Q9H061,Q6DKK2,Q96CU9,Q69YU5,Q9Y375,P03886,O96000,O95831 10 +Regulation of skeletal muscle tissue development 0.8438242413210184 2.366458091349913 0.0179592074189618 1.0 0.06747485343681 6 P41440 1 +Regulation of neurotransmitter transport 0.7241831791211119 2.366261811556674 0.0179687324206918 1.0 0.06747485343681 14 P41440,Q4J6C6 2 +T helper 17 type immune response 0.6590100291167929 2.364489964336349 0.0180549165125525 1.0 0.0677191426831256 2 P40763 1 +Response to food 0.7995612299195458 2.363609370668861 0.0180978838263576 1.0 0.0678406054543583 5 Q9UMX5 1 +Postsynapse to nucleus signaling pathway 0.6544807505661623 2.3404498232977224 0.0192605263165615 1.0 0.071117496364723 2 P52292 1 +Negative regulation of autophagosome assembly 0.70158069445784 2.335022350589422 0.0195422531694895 1.0 0.0715215550403236 3 O75396 1 +Embryonic hemopoiesis 0.7489851649754629 2.3273879957872654 0.0199446240877523 1.0 0.0727132918688233 4 Q9H6E4 1 +Transferrin transport 0.7480386067919207 2.322940240175634 0.020182363004392 1.0 0.0730898004848321 4 P50570 1 +Activation of phospholipase d activity 0.6985773815291402 2.3200286710436484 0.0203393263945366 1.0 0.0734921545597405 3 P40616 1 +Negative regulation of regulated secretory pathway 0.7471693262186803 2.318853509701043 0.0204029806476779 1.0 0.0736806230713328 4 P09601 1 +Negative regulation of leukocyte migration 0.7889866082383029 2.3163590127986593 0.0205386746998461 1.0 0.0740871721024276 5 P09601 1 +Branching involved in mammary gland duct morphogenesis 0.6489809123261112 2.3111631903844696 0.0208238427130482 1.0 0.0746119797600004 2 Q15648 1 +Regulation of phospholipase c activity 0.6489809123261101 2.3111631903844656 0.0208238427130484 1.0 0.0746119797600004 2 P35232 1 +Activation of phospholipase c activity 0.6489809123261101 2.3111631903844656 0.0208238427130484 1.0 0.0746119797600004 2 P35232 1 +Activation of protein kinase c activity 0.6489809123261101 2.3111631903844656 0.0208238427130484 1.0 0.0746119797600004 2 P35232 1 +Peroxisome fission 0.7851027525720093 2.298937725727213 0.0215084757782209 1.0 0.0765515434416413 5 O14734,O96011,Q9Y3D6 3 +Lymphocyte costimulation 0.6936753563994219 2.295497509646712 0.0217046289666453 1.0 0.0771639887277852 3 P07948 1 +Respiratory chain complex iii assembly 0.783674944802855 2.2925241290880014 0.0218754168293895 1.0 0.077556096170568 5 Q69YU5 1 +Proteolysis 0.3328625754926236 2.290836848509195 0.0219728515680928 1.0 0.0777073272873148 360 P42785,P46379,P49721,Q9P0J0,Q9UL46,O43847,Q9NWU2,Q5JRX3,Q4J6C6,Q9BZK7,Q9NZ08,P55786,Q9UJZ1,O00231,P42892,P02786,Q9Y3D6,Q96K76,Q92896,Q7Z2K6,Q16763,P17655,Q9Y5A7,P23396,Q99436,P48147,Q96TA2,Q8IXB1,Q15392,Q99627,P28070,Q5TDH0,Q96PU5,O14773,O95831,P28074,Q9H3G5,Q92530,Q96HY6,Q96J02,Q9UHG3,P28072,Q92575,O43464,Q96F07,Q9UIQ6,O75503,P20618,P52888,Q15375,Q06481,O75976,Q13794,Q9BYT8,Q9UJX3,Q96JB5,Q92643,Q9NXR7,P07948,Q8N163,O75844,O75787,Q9HB40,P60520,P51572,P09960,Q05086,Q8NBM8,Q9BT78,Q10713,Q9H2J4,Q9NUQ7,P78318 73 +Phosphatidylinositol dephosphorylation 0.7410716781406559 2.29013043409614 0.0220137566019522 1.0 0.0777073272873148 4 Q13614 1 +Phospholipid dephosphorylation 0.7410716781406559 2.29013043409614 0.0220137566019522 1.0 0.0777073272873148 4 Q13614 1 +Proteasome assembly 0.7408687674546126 2.2891729242738452 0.0220693070944948 1.0 0.0778559485281848 4 O95456 1 +Positive regulation of chemokine c c motif ligand 5 production 0.642186994500171 2.2748415398239743 0.0229154373202757 1.0 0.0798738190445804 2 Q7Z434 1 +Inflammasome complex assembly 0.642186994500165 2.274841539823941 0.0229154373202777 1.0 0.0798738190445804 2 P19525 1 +Positive regulation of protein k63 linked ubiquitination 0.6421869945001633 2.2748415398239334 0.0229154373202782 1.0 0.0798738190445804 2 P61088 1 +Late endosome to golgi transport 0.6412164348107425 2.26963972997849 0.0232294509779642 1.0 0.0808031167092229 2 Q9UMY4 1 +Vascular process in circulatory system 0.581056133013375 2.269589986032594 0.0232324717777063 1.0 0.0808031167092229 29 P30825,O94813,Q15758,Q9HB40,P41440,Q16625,P23634,P42892,P08183 9 +Protein import into mitochondrial matrix 0.7584850127143852 2.267106167680958 0.0233837409014792 1.0 0.0811091878671437 11 O60830,Q99595 2 +Neutral lipid biosynthetic process 0.7973136926638271 2.2605741942854185 0.0237856372352758 1.0 0.0821918785326781 8 Q8WTV0,Q8NCC3 2 +Intracellular lipid transport 0.6925264119336672 2.260083115733494 0.0238160928379429 1.0 0.0822527775275939 15 Q9Y5P4,Q9P260,O15118,P23786,O43772 5 +Regulation of muscle organ development 0.796695251390068 2.2578031012948228 0.0239579377946566 1.0 0.082698105150107 8 P41440,P16989 2 +Negative regulation of inflammatory response to antigenic stimulus 0.7758988130570019 2.257508751069514 0.0239763032931497 1.0 0.0827169559252366 5 P28070 1 +Monovalent inorganic cation homeostasis 0.5751131876371948 2.256429396619244 0.024043752347066 1.0 0.0829050309546493 30 O75503,P51790,P0CG08,Q05086,Q9Y487,Q9HC07,Q96PU5,P50897,Q93050,Q9Y6M7 10 +Nucleobase containing small molecule biosynthetic process 0.8178128438025242 2.2551432097588253 0.0241243411891445 1.0 0.0830935126396649 6 P55263 1 +Glycosyl compound biosynthetic process 0.8178128438025242 2.2551432097588253 0.0241243411891445 1.0 0.0830935126396649 6 P55263 1 +Srp dependent cotranslational protein targeting to membrane signal sequence recognition 0.6383047557424839 2.254014793978792 0.0241952373008169 1.0 0.0832236057779099 2 P09132 1 +Exocrine pancreas development 0.6383047557424817 2.254014793978781 0.0241952373008176 1.0 0.0832236057779099 2 O00330 1 +Synaptic vesicle priming 0.6379812358460077 2.2522768838569625 0.0243047800268902 1.0 0.0835354637921537 2 O00161 1 +Negative regulation of tumor necrosis factor superfamily cytokine production 0.6849388065622694 2.2515976488814684 0.0243477097798869 1.0 0.0836381670359461 3 O43823 1 +Cellular response to growth hormone stimulus 0.6844660194174691 2.249215399597535 0.0244987951804964 1.0 0.0840220851294799 3 P40763,P07948 2 +Growth hormone receptor signaling pathway via jak stat 0.6844660194174691 2.249215399597535 0.0244987951804964 1.0 0.0840220851294799 3 P40763,P07948 2 +Positive regulation of protein tyrosine kinase activity 0.684466019417461 2.2492153995974964 0.0244987951804989 1.0 0.0840220851294799 3 Q13432,Q8IZP0 2 +Ion transmembrane transport 0.3845027642902939 2.2470384932272194 0.0246375671551526 1.0 0.0844076993396731 163 Q9HD20,Q8TDW0,Q70HW3,P21796,P0CG08,Q6P4A7,O43772,Q9HC07,Q9UJZ1,P41440,P45880,Q96PU5,P23634,P13073,Q9Y6M7,Q9C0H2,Q9UHG3,P50570,P00846,O95563,Q4KMQ2,P27105,P08183,Q86VD7,P07948,P33527,P30825,P28161,Q15758,Q13423,Q7KZN9,O75844,Q9Y619,P51790,Q9BQT8 35 +Cellular monovalent inorganic cation homeostasis 0.5815649158421798 2.2462250505348353 0.0246895964581039 1.0 0.0844531380052952 28 O75503,P51790,P0CG08,Q05086,Q9Y487,Q9HC07,Q96PU5,Q93050,Q9Y6M7 9 +Response to progesterone 0.7305007389557098 2.2401021323887393 0.0250842931413584 1.0 0.0855267654447379 4 Q05086 1 +Neuron development 0.3839940517682636 2.2391479168038484 0.0251462933840986 1.0 0.0856573719136997 163 Q13614,O94813,Q32P28,Q9Y4G8,Q14108,P50897,P42892,P84095,Q9BUP0,Q8NHS3,Q13641,P41440,Q9NR77,Q13555,Q96PU5,Q9UQB8,Q9Y6M7,P54802,P08670,P50570,O43464,Q96F07,O75503,Q06481,Q9NQX7,P07948,Q9UBB6,P46108,Q05086,Q86X55,Q96G23,P07196 32 +Hindlimb morphogenesis 0.6353930766742195 2.238360599921576 0.025197549208044 1.0 0.0856573719136997 2 Q15648 1 +Embryonic hindlimb morphogenesis 0.6353930766742195 2.238360599921576 0.025197549208044 1.0 0.0856573719136997 2 Q15648 1 +Regulation of morphogenesis of an epithelium 0.6353930766742182 2.2383605999215694 0.0251975492080445 1.0 0.0856573719136997 2 Q99623 1 +Negative regulation of response to cytokine stimulus 0.7299671719614157 2.237569101109435 0.0252491684131113 1.0 0.0856631887449806 4 Q14166,O94813 2 +Motor neuron axon guidance 0.7714455648366825 2.2373909378287027 0.0252608003055205 1.0 0.0856631887449806 5 O94813 1 +Retrograde transport vesicle recycling within golgi 0.7713730569948181 2.237062986909593 0.0252822236327341 1.0 0.0856631887449806 5 P83436,Q9UP83,Q8TBA6,Q9Y2V7 4 +Neurotransmitter transport 0.5960644882401809 2.2300396607721313 0.0257448100005919 1.0 0.0869463815088483 23 P41440,P05771,Q4J6C6 3 +Regulation of camp dependent protein kinase activity 0.7272904467957801 2.224850347324295 0.0260912862087843 1.0 0.0876546879446055 4 Q9Y4G8 1 +Actin myosin filament sliding 0.6792540406262725 2.222908959632674 0.0262219395037857 1.0 0.0878838744649759 3 P14649 1 +Regulation of neuron projection development 0.4553207529053142 2.2222089291028286 0.0262691893096558 1.0 0.0878838744649759 61 P07948,O94813,P08670,Q32P28,Q9NR77,P46108,Q13555,Q15375,Q05086,Q96PU5,Q9Y4G8,Q14108,Q9UQB8,Q96G23,Q8N0X7,Q86X55,Q9NQX7,P07196 18 +Positive regulation of protein localization to early endosome 0.6786067914353339 2.2196363816853384 0.0264434605453112 1.0 0.0883746517703049 3 P35241 1 +Regulation of protein localization to endosome 0.6786067914353339 2.2196363816853384 0.0264434605453112 1.0 0.0883746517703049 3 P35241 1 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.6607039341776957 2.215079315201568 0.0267546209353681 1.0 0.0891603242091995 17 O95831,P46379 2 +Peptide catabolic process 0.764058013732639 2.214971703179976 0.0267620068297191 1.0 0.0891603242091995 10 P42892,Q9UIQ6,Q9NZ08,P55786 4 +Response to cell cycle checkpoint signaling 0.6773462783171342 2.2132594373807684 0.0268797644028284 1.0 0.0894596520364124 3 Q9NQ88,O75844 2 +Histone h3 k4 demethylation 0.6772325112315274 2.21268365344648 0.0269194631506837 1.0 0.0895452821981747 3 Q9H6W3 1 +Organic cation transport 0.7965361222357261 2.20826502205889 0.0272258041003263 1.0 0.0901898730145178 7 Q70HW3,O43772 2 +Anion transport 0.4468568620695501 2.20697621753571 0.027315720905551 1.0 0.0902545211363824 78 Q8TDW0,P21796,P0CG08,P41440,Q9UHQ9,P45880,O43681,Q9Y6M7,Q9C0H2,Q9UHG3,Q4KMQ2,Q08722,O95563,Q9Y5P4,Q99808,P08183,Q86VD7,P30825,Q15758,Q9Y619,P51790,Q9BQT8 22 +Endoplasmic reticulum mannose trimming 0.6292461986412241 2.2052168079681773 0.0274388842888044 1.0 0.0905877970515914 2 Q8WU17 1 +Endomembrane system organization 0.3836203070876407 2.2051317301720115 0.0274448520864571 1.0 0.0905877970515914 150 Q96FZ7,Q00765,P46379,Q14203,O75396,O00429,P50402,Q14108,P40616,P20700,P41440,Q96CP7,O43681,Q9UQB8,Q13190,Q9NVJ2,Q9BRK0,Q9H5V9,P50570,Q86XL3,Q6IAA8,Q9Y5P4,Q4KMQ2,O94901,O94979,Q12981,Q9UP83,Q9P2W9,Q9Y2V7,Q9P0I2,P05771,Q9C0E8,Q9NPA0,P83436,O75844,Q5JTV8,P53350,O43760,P31751,Q92538,P51790,Q8N1F7,Q9ULX6,P35579,P06493,Q9H267,Q8NHH9 47 +Positive regulation of striated muscle cell apoptotic process 0.6748284870658433 2.200507588731797 0.0277709021216483 1.0 0.0912879397947517 3 P17655 1 +Neuron differentiation 0.3739384261203242 2.1987620736316416 0.0278948445805491 1.0 0.0915545078142959 194 Q8WUJ1,Q13614,O94813,Q32P28,Q9Y4G8,Q14108,P50897,P42892,P84095,Q9BUP0,Q8NHS3,Q13641,P41440,Q9NR77,Q13555,Q96PU5,Q9UQB8,P23634,Q9Y6M7,P54802,P08670,P50570,O43464,Q96F07,O75503,Q06481,Q9NQX7,P07948,Q9UBB6,P46108,Q05086,Q86X55,Q96G23,P07196 34 +Chloride transport 0.7100294077770017 2.1981270031545836 0.027940056714353 1.0 0.0916090862092087 13 Q9C0H2,Q9UHG3,P08183 3 +Regulation of pigmentation 0.673468186567959 2.193610138169008 0.0282634489542077 1.0 0.0923387909258265 3 Q96AX1 1 +Toll like receptor signaling pathway 0.7084809229754718 2.1901681058868077 0.0285120473980533 1.0 0.0930087653035735 13 P41440,Q06481,Q5KU26,Q9NPR9 4 +Amelogenesis 0.6718446601941591 2.185370702643997 0.0288616771890262 1.0 0.0940057676736067 3 Q6P4Q7,Q13586 2 +Enamel mineralization 0.6718446601941591 2.185370702643997 0.0288616771890262 1.0 0.0940057676736067 3 Q6P4Q7,Q13586 2 +Positive regulation of tau protein kinase activity 0.6237463604011693 2.175451437027131 0.0295963035285795 1.0 0.0960392799977347 2 P07900 1 +Negative regulation of transforming growth factor beta production 0.6237463604011693 2.175451437027131 0.0295963035285795 1.0 0.0960392799977347 2 Q9Y5K6 1 +Regulation of tau protein kinase activity 0.6237463604011693 2.175451437027131 0.0295963035285795 1.0 0.0960392799977347 2 P07900 1 +Xenobiotic transport 0.7577720207253875 2.175323689279547 0.0296058685297229 1.0 0.0960392799977347 5 P41440,P08183,P35670,P33527 4 +Response to leucine 0.6697410617563215 2.174683098435619 0.0296538723104813 1.0 0.0961463437077315 3 Q9P2J5 1 +Detection of biotic stimulus 0.6695636121930636 2.173780934457716 0.0297215910294372 1.0 0.0963171883208761 3 Q8WTV0 1 +Positive regulation of mitochondrial membrane potential 0.716192175120447 2.1719131808181587 0.0298622120881733 1.0 0.0966263399723326 4 P31751 1 +Regulation of ligase activity 0.6686084142394849 2.1689230262433705 0.0300885282618124 1.0 0.0972604468775681 3 P18887,Q9UBB9 2 +Mast cell activation involved in immune response 0.7970384542003015 2.1651877038486904 0.0303733136092387 1.0 0.0979340745650003 6 P09601 1 +Calcium mediated signaling using intracellular calcium source 0.6677503625889891 2.164556843343634 0.0304216390186191 1.0 0.0979955877853041 3 P51572 1 +Chemical homeostasis 0.3749344118261394 2.16393200700193 0.0304695680547728 1.0 0.0980021857528395 183 O15254,Q9HD20,P42785,P30519,P0CG08,O15118,Q9HCL2,Q9HC07,P50897,P04114,Q9UJZ1,P02786,Q5BJF2,Q9Y3D6,P49366,O00459,O95793,Q96CP7,Q96AX1,Q9Y487,Q96PU5,P23634,P04899,Q9Y6M7,Q6IAA8,O95563,Q9Y5P4,P09601,O75503,Q06481,Q96RR1,Q99808,Q8WTV0,Q12824,P05771,P28161,P07948,O75787,O43819,P51572,P51790,Q05086,Q93050 43 +Immune response regulating cell surface receptor signaling pathway 0.5855349425532922 2.161185807266277 0.0306809893092501 1.0 0.0980927359410281 23 P07948,P46379,P23396,Q08722,Q06481,Q9UJZ1,P05771 7 +Bone remodeling 0.7752377009178769 2.1611081568253288 0.0306869856399822 1.0 0.0980927359410281 8 Q9UBB6,Q92791,O14773 3 +Positive regulation of developmental pigmentation 0.6208346813329073 2.1596511426361924 0.0307996860885235 1.0 0.0983687034516373 2 O60315 1 +Regulation of vascular permeability 0.7837637474712849 2.151670308673254 0.0314233302397963 1.0 0.1000116915775048 7 Q16625 1 +Regulation of pattern recognition receptor signaling pathway 0.6610366275525372 2.1506550218655662 0.0315034389682538 1.0 0.1001671844179101 16 P41440,Q06481,Q96RT1,Q9NPR9 4 +Regulation of toll like receptor signaling pathway 0.761613269641013 2.1493564478662592 0.0316061550392623 1.0 0.1002947791097384 9 P41440,Q06481,Q9NPR9 3 +Positive regulation of histone phosphorylation 0.6188935619540665 2.149101418988265 0.0316263613089899 1.0 0.1003092409651785 2 Q06787 1 +Ph reduction 0.7001922121186245 2.1474470387484232 0.0317577092340073 1.0 0.1006674962647125 13 P51790,O75503,P0CG08,Q05086,Q9Y487,Q93050 6 +Skeletal muscle organ development 0.5804971746680493 2.1472834241238017 0.0317707246401737 1.0 0.1006674962647125 24 P16989,P41440,Q9BYT8,Q9Y5Q8,P80723 5 +Integrin activation 0.6166289226787498 2.136777050953856 0.0326161295554447 1.0 0.1025855694064775 2 Q9Y490 1 +Purine deoxyribonucleoside triphosphate metabolic process 0.662166743647511 2.1360906974051006 0.0326720218618952 1.0 0.1027109662259678 3 P55263 1 +Regulation of regulated secretory pathway 0.6462951019250527 2.1330234403798305 0.03292280336773 1.0 0.1032252262894843 17 P05771,P09601,Q4J6C6,P04899 4 +Hematopoietic stem cell homeostasis 0.7059513799068182 2.1227772394950444 0.0337725229755416 1.0 0.1054813366627379 4 Q9NX40 1 +Vitamin d receptor signaling pathway 0.6585760517799366 2.117735431618597 0.0341974803581925 1.0 0.1060843484380581 3 Q15648,Q13573 2 +Regulation of vitamin d receptor signaling pathway 0.6585760517799366 2.117735431618597 0.0341974803581925 1.0 0.1060843484380581 3 Q15648,Q13573 2 +Protein insertion into membrane 0.5589874121747098 2.1152428284671423 0.03440925640113 1.0 0.106603834476193 29 P46379,Q9P0J0,Q9NS69,P60602,Q9Y584,P62072,Q9NPA0 7 +Lipid localization 0.442402068446714 2.113385953610958 0.0345677472162093 1.0 0.106991433923661 71 Q9BZF3,Q9H6V9,P50416,Q9Y5P4,Q99720,Q9P260,P31751,O15118,P23786,O43772,Q14108,Q8WTV0,P08183 13 +Lymphocyte activation 0.425472606610154 2.1110576473171756 0.0347673571900422 1.0 0.1072581134680755 91 P46379,P12956,P0CG08,Q9UQ84,Q9HCL2,Q9NQT5,Q9UJZ1,P02786,P49366,P23396,P24390,Q96J02,Q08722,P17812,P05771,P07948,P30825,Q9BXW9,O43290,O96028,P78318 21 +Retrograde transport endosome to golgi 0.5505211783097063 2.1101814001502617 0.034842733993109 1.0 0.1072581134680755 31 Q92538,O75503,Q4J6C6,Q14203,Q93009,O60499,P14373,O60749,Q13190,O95249,P53367,P40616 12 +Positive regulation of actin nucleation 0.6561143866741999 2.1051293583039055 0.0352800493064708 1.0 0.1081516576061589 3 P14373 1 +Pyrimidine deoxyribonucleoside metabolic process 0.6091879650598566 2.0961589255645428 0.0360680952411773 1.0 0.1095801433175312 2 P04183 1 +Negative regulation of mrna catabolic process 0.5720710443101656 2.091157616927524 0.0365139372191547 1.0 0.1103541831617156 24 Q99729,P16989,Q15717,Q14011,P67809,Q92804,Q06787,P98175,O60506,P07910,P11940 11 +Intrinsic apoptotic signaling pathway in response to dna damage 0.5748168826327703 2.0905878816297125 0.0365650229965333 1.0 0.1103807768192096 23 Q8N163,P46379,Q9HBM6,O43464,P09601,P61978,Q96K76 7 +Response to bacterium 0.4576197981789457 2.089277928358037 0.0366827120327333 1.0 0.1104444265522877 54 P07948,Q9Y4Y9,P08670,Q86U42,P60602,Q9NZ08,O43823,Q9UQB8,Q8WTV0,P04114,Q96EE3,Q96RT1,Q5KU26 13 +Negative regulation of protein exit from endoplasmic reticulum 0.6985925173256533 2.0872985124235965 0.0368611591771923 1.0 0.1107216636953153 4 Q96DZ1,Q8NBM4 2 +Regulation of membrane lipid distribution 0.7384196959005984 2.0867181214753403 0.0369136222088224 1.0 0.1108273153904224 5 P08183,Q96CP7,Q4KMQ2 3 +Amyloid beta clearance by cellular catabolic process 0.6069233257845413 2.0837593101712035 0.0371820662549531 1.0 0.111476634562325 2 P14735 1 +Negative regulation of glial cell differentiation 0.6069233257845408 2.0837593101712013 0.0371820662549533 1.0 0.111476634562325 2 P35222 1 +Positive regulation of heart rate 0.6062762859915942 2.0802133498553497 0.0375059683034291 1.0 0.1120285446528334 2 P09493 1 +Purine ribonucleoside metabolic process 0.757232685018935 2.0791520844254014 0.0376033741249761 1.0 0.1121626934113993 8 P55263,Q13126,O60725 3 +Ribonucleoside metabolic process 0.757232685018935 2.0791520844254014 0.0376033741249761 1.0 0.1121626934113993 8 P55263,Q13126,O60725 3 +Localization within membrane 0.3730576219347802 2.0786515913723527 0.0376493853769568 1.0 0.1122385214455238 167 Q9HD20,P46379,Q9P0J0,O95429,Q9NS69,Q4J6C6,O15118,Q9Y4G8,P84095,Q5BJH7,Q13641,P41440,P60602,Q6IQ22,P43307,P35241,P23634,Q9BRK0,P50570,Q9Y584,P27105,Q9BZG1,P31751,O60725,O15400,P62072 26 +Dendrite extension 0.7362817845235652 2.0768751678893382 0.0378130822030142 1.0 0.1125263959709013 5 Q96F07,Q96PU5 2 +Torc1 signaling 0.7762660316150988 2.074310690428092 0.0380504656059923 1.0 0.1131802712456663 6 Q8NHS3,Q96EE3,Q9P2J5 3 +Histone h3 k9 acetylation 0.6958287701747494 2.0739371907205912 0.0380851444850018 1.0 0.1132308794753534 4 Q03164,Q12824 2 +Central nervous system neuron development 0.7329851931887246 2.0677523778200064 0.0386633138599985 1.0 0.1147369638160142 10 O94813 1 +Regulation of cellular ph 0.5712372417122167 2.066895343012801 0.0387440166630244 1.0 0.1148700956567929 23 Q96AX1,O75503,P0CG08,P51790,Q05086,Q9Y487,Q9HC07,P50897,Q93050,Q9Y6M7 10 +Regulation of ph 0.5712372417122167 2.066895343012801 0.0387440166630244 1.0 0.1148700956567929 23 Q96AX1,O75503,P0CG08,P51790,Q05086,Q9Y487,Q9HC07,P50897,Q93050,Q9Y6M7 10 +T cell homeostasis 0.7738288946822256 2.0635879449614394 0.0390568015473107 1.0 0.1156736885321364 6 Q13794 1 +Glycerophospholipid catabolic process 0.7316528057270482 2.0613863971529978 0.0392661915553813 1.0 0.1160960737407723 10 Q8WTV0,Q8NCC3 2 +Negative regulation of programmed necrotic cell death 0.6931374845463658 2.060906995719064 0.0393119137637343 1.0 0.1161241323619986 4 P16989 1 +Negative regulation of necrotic cell death 0.6931374845463658 2.060906995719064 0.0393119137637343 1.0 0.1161241323619986 4 P16989 1 +Homologous chromosome pairing at meiosis 0.742462987631526 2.0602003120311267 0.0393793951094596 1.0 0.1162163548119872 9 Q92791,O94901,Q9BXW9,P46379 4 +Lytic vacuole organization 0.5693012162237147 2.0540577296932185 0.039970104595306 1.0 0.1173115249340254 23 Q9BZG1,Q8NHS3,P54802,Q6IAA8,Q96AX1,O75503,Q9HC07,Q14108,P50897,O14773 10 +Negative regulation of immunoglobulin production 0.6010999676480162 2.0517943718933123 0.0401896505102361 1.0 0.1177940831141352 2 P55061 1 +Adenylate cyclase activating g protein coupled receptor signaling pathway 0.730351361211648 2.0495151285646247 0.0404117700451016 1.0 0.1183207735748779 5 Q9Y4G8,P23634 2 +Sterol transport 0.5708317498835546 2.046913278642523 0.0406666000858815 1.0 0.1183207735748779 22 O15118,Q9BZF3,Q9P260,Q8WTV0 4 +Regulation of systemic arterial blood pressure 0.750116024976795 2.046553602908898 0.0407019343328023 1.0 0.1183207735748779 8 P42785 1 +Regulation of vesicle mediated transport 0.4022255959964345 2.0425063950044984 0.041101325727618 1.0 0.1188360387523823 106 Q13614,P50570,Q08722,P41440,P31751,P09601,P61978,Q4J6C6,Q6IQ22,P50897,Q13432,Q06481,Q96PU5,P35241,P04899,Q8WTV0,P53367,P05771 18 +External encapsulating structure organization 0.5816814321721155 2.0347215198933903 0.0418789016003371 1.0 0.1205405295276879 21 Q92791,P41440,O75718,Q53GQ0,Q96AY3 5 +Membrane organization 0.3551009922935476 2.0304914482663974 0.0423066095608795 1.0 0.1215197004096204 219 Q96FZ7,Q00765,P46379,Q9P0J0,Q9NS69,Q14203,O75396,O00429,P50402,O15118,P50897,P04114,Q92734,P84095,O14653,P20700,P41440,Q8WWC4,P60602,Q96CP7,Q13505,Q5XKP0,Q15392,P45880,O43681,Q9UQB8,Q13190,Q9NVJ2,Q9BRK0,Q9H5V9,P50570,Q86XL3,Q4KMQ2,Q9Y5P4,O94901,Q9NX63,O94979,Q12981,Q9Y584,Q06481,Q9P2W9,Q13794,Q9P0I2,P05771,P08183,P33527,Q9BZG1,O75844,Q5JTV8,P53350,O43760,P31751,Q92538,Q8NHH9,P51790,Q8N1F7,Q9ULX6,O15400,O60499,P62072,P35579,Q9NPA0,Q9H267,O75431 64 +Modified amino acid transport 0.7662436838655848 2.030134263516425 0.0423428935536098 1.0 0.1215197004096204 6 O43772 1 +Trna wobble uridine modification 0.6867833049606797 2.0300675652891975 0.0423496718931126 1.0 0.1215197004096204 4 O75648 1 +Regulation of plasma membrane organization 0.641524838465086 2.0300466686590526 0.0423517957433841 1.0 0.1215197004096204 3 P50570 1 +Protein insertion into mitochondrial inner membrane 0.7546227819813166 2.0211907851111155 0.0432600192482737 1.0 0.1233526349561541 7 P62072,Q9Y584,P60602 3 +Cellular component morphogenesis 0.3826272124191849 2.0089958936487635 0.0445375692214802 1.0 0.1262507252237814 117 Q13614,Q9BRT6,O94813,Q9Y4F1,P28289,Q9Y4G8,P42892,Q9Y3D6,P84095,Q13641,Q13045,P41440,Q9NR77,O00264,Q96PU5,Q9UQB8,Q8N0X7,P50570,Q9Y5P4,Q96F07,Q15375,Q06481,Q92766,Q9NUL3,Q05086,P07196 26 +Regulation of retrograde protein transport er to cytosol 0.7215875122138874 2.0089321350124623 0.0445443313998938 1.0 0.1262507252237814 5 Q96DZ1,P51572,Q8NBM4 3 +Adiponectin activated signaling pathway 0.6368932038834719 2.006079036047458 0.0448478161540371 1.0 0.126752425726357 3 Q06481,P67870 2 +Epidermis morphogenesis 0.6355987055016215 1.999369038864592 0.0455684393018862 1.0 0.1281931968064015 3 O60568,Q04656 2 +Positive regulation of cell cell adhesion 0.5492782295640755 1.998491347393351 0.0456634170769365 1.0 0.1283782909926155 27 P07948,P30825,P23396,P55196,P41440,Q08722,O43290,Q9HCL2,P02786,P04439,P49366 11 +Regulation of glucose transmembrane transport 0.7183443462414434 1.9975626222979583 0.0457640989344008 1.0 0.1286049426433622 10 P31751,P05771,Q16625 3 +Regulation of post translational protein modification 0.6343941509321149 1.993120853588073 0.0462482150115639 1.0 0.1293981048555761 3 Q32P28 1 +Ion transport 0.3543330909690389 1.98944960306415 0.0466515992316742 1.0 0.1303560379577298 215 Q9HD20,Q8TDW0,Q70HW3,P21796,P0CG08,Q6P4A7,O43772,Q9HC07,Q9UJZ1,P02786,P41440,Q9UHQ9,O15173,Q13555,P45880,Q96PU5,O43681,P23634,P13073,P04899,Q9Y6M7,Q9C0H2,Q9UHG3,P50570,P00846,O95563,Q9Y5P4,Q08722,Q4KMQ2,P27105,Q99808,P05771,P08183,Q86VD7,P07948,P33527,P30825,P28161,Q15758,Q13423,Q7KZN9,O75844,Q9Y619,P51790,Q9BQT8 45 +Maintenance of organelle location 0.5884826916855448 1.9821433751045017 0.0474631961042775 1.0 0.1320482148560846 2 Q5T280 1 +Maintenance of centrosome location 0.5884826916855448 1.9821433751045017 0.0474631961042775 1.0 0.1320482148560846 2 Q5T280 1 +Protein depalmitoylation 0.6767925562951624 1.9813669455007443 0.0475501378185527 1.0 0.1322327043023528 4 Q8N2K0,P50897 2 +Myeloid cell activation involved in immune response 0.7355572264857364 1.9795086151731924 0.047758770636952 1.0 0.1326402598712575 8 P09601 1 +Negative regulation of glycoprotein metabolic process 0.6763058988924551 1.9789881380045935 0.0478173418092304 1.0 0.1327454140308217 4 Q9NQX7 1 +Pinocytosis 0.7447591220039379 1.9766041516478037 0.0480863925117287 1.0 0.1334345350650135 7 Q9BZG1,P50570,P50897 3 +Negative regulation of lipid localization 0.6750491562577904 1.972842306858675 0.04851353138583 1.0 0.134116645035361 4 P31751 1 +Tooth mineralization 0.6742117910010164 1.9687451081777465 0.0489823685529104 1.0 0.1351601301868946 4 Q6W2J9,Q6P4Q7 2 +Nuclear body organization 0.6739878773610779 1.9676492029925456 0.0491084142760835 1.0 0.1353331622999552 4 O75312,Q15637 2 +Regulation of synaptic vesicle exocytosis 0.7120122264317112 1.9670449803914756 0.0491780253787914 1.0 0.135417742935837 10 Q4J6C6 1 +Regulation of long term neuronal synaptic plasticity 0.5849239728243356 1.9624016655066812 0.0497157390204352 1.0 0.1365697434557967 2 P20339 1 +Synaptonemal complex organization 0.7416108782450471 1.9623288721848693 0.0497242078654835 1.0 0.1365697434557967 7 P46379 1 +Neurotransmitter secretion 0.6164637718253593 1.9608597804696328 0.049895382169816 1.0 0.1368546853694996 17 P05771,Q4J6C6 2 +Vitamin transmembrane transport 0.7380913287963768 1.946344759038604 0.0516133404375687 1.0 0.1410838005137805 7 P41440,Q8WTV0 2 +3 phosphoadenosine 5 phosphosulfate biosynthetic process 0.5816887738595997 1.94441812444592 0.051845049982671 1.0 0.1415137719669255 2 O43252 1 +Bone resorption 0.7370512519998293 1.9416161527473936 0.0521835859633534 1.0 0.1420368518153273 7 Q9UBB6,O14773 2 +Cell cycle dna replication initiation 0.7462567335146003 1.941404004600236 0.0522092929497124 1.0 0.1420465058606353 6 P25205,Q9BRX5 2 +Neutral amino acid transport 0.6685521965295032 1.94100604934609 0.0522575436219197 1.0 0.1421174605924927 4 Q96NB2,Q15758 2 +Positive regulation of endocytosis 0.6015729605911314 1.9389793844630745 0.0525038484865323 1.0 0.1426057918638441 18 P50570,P41440,P61978,Q06481,Q96PU5,P50897 6 +Carbohydrate mediated signaling 0.6670205351897538 1.9334850195935 0.0531764767447739 1.0 0.1442493507972921 4 Q5KU26 1 +Protein hydroxylation 0.6589401894252281 1.9318886633986565 0.0533732493270049 1.0 0.1445995469932804 13 Q92791,Q32P28,O75718,Q96AY3,P13674 5 +Vacuolar localization 0.6222026454329346 1.9316532517184908 0.0534023184036061 1.0 0.1446171782708555 16 P07948,Q9BZG1,Q9NVJ2,Q6IAA8,P09601,Q96AX1,Q9H267 7 +Protein polymerization 0.4265322357488116 1.9302162053341745 0.0535800544533862 1.0 0.1449760021300994 67 O94813,O95429,Q14203,P28289,P36405,Q16763,Q13045,P23396,Q16625,P62993,P45880,P35241,Q9UQB8,P35611,Q96F07,Q9NUQ9,Q9BSJ2,Q9UEY8,Q96P70,P07196 20 +Positive regulation of glucose metabolic process 0.7040326811486832 1.927105088217162 0.0539665347707003 1.0 0.1456934476501279 5 Q13794 1 +Positive regulation of cellular carbohydrate metabolic process 0.7040326811486832 1.927105088217162 0.0539665347707003 1.0 0.1456934476501279 5 Q13794 1 +Negative regulation of cell projection organization 0.5290074393836217 1.926773973758797 0.0540078043146368 1.0 0.1456934476501279 30 O94813,P08670,P50570,Q9NR77,Q05086,Q9Y4G8,Q96G23,Q8N0X7,Q86X55,Q9NQX7 10 +T cell proliferation 0.5501174633348956 1.925965634465098 0.0541086650087314 1.0 0.145852204670298 23 Q96J02,P30825,P23396,P17812,Q9HCL2,P02786,P49366 7 +Neuron projection guidance 0.5992062668790816 1.9248196912363764 0.0542519196421151 1.0 0.1461154642462009 18 O94813,Q15375,O00264,Q9BPU6,P42892,P84095 6 +Centriole centriole cohesion 0.6207461717429825 1.9220322193139727 0.0546017037612336 1.0 0.1466252728152384 3 Q14203 1 +Protein localization to endoplasmic reticulum exit site 0.7029404906270358 1.9219908136361712 0.054606913670963 1.0 0.1466252728152384 5 Q92538,P51572 2 +Vesicle fusion with golgi apparatus 0.6646711397057994 1.9219370922069023 0.0546136738400777 1.0 0.1466252728152384 4 Q13190 1 +Copper ion transport 0.620711974110029 1.921853417856741 0.0546242045994991 1.0 0.1466252728152384 3 P35670,Q04656 2 +Collagen fibril organization 0.722494893997006 1.9189520202258257 0.054990406246614 1.0 0.1474230464411525 8 Q96AY3,Q92791,O75718 3 +Regulation of histamine secretion by mast cell 0.5768359754124955 1.9173779956650483 0.0551899276384846 1.0 0.1478960853522936 2 P51809 1 +Pigment metabolic process 0.5372280767205774 1.9142015565935728 0.0555944069527964 1.0 0.1489177386407962 27 P22830,Q7KZN9,P09601,P30519,Q9Y4G8 5 +Cellular response to reactive nitrogen species 0.730908159740912 1.9136402286725671 0.0556661411336816 1.0 0.1489853714684339 7 O95831,P50570 2 +Response to nitric oxide 0.730908159740912 1.9136402286725671 0.0556661411336816 1.0 0.1489853714684339 7 O95831,P50570 2 +Negative regulation of proteolysis 0.4252841834121258 1.912473042194963 0.0558155471235852 1.0 0.1493228952680223 63 Q96HY6,Q8N163,P46379,P78318,P60520,Q15392,Q06481,Q92896,Q96K76,Q92530 10 +Vacuole organization 0.4611356959871026 1.9122252808173927 0.0558473048196639 1.0 0.1493455251956803 47 Q9BZG1,Q8NHS3,Q96KQ7,P54802,Q6IAA8,O75787,P60520,Q96AX1,O75503,O75396,Q9HC07,Q14108,P50897,Q8TBX8,O14773,O95817 16 +Protein localization to golgi apparatus 0.7102895291567797 1.9084767954252293 0.0563296195150671 1.0 0.1502772972967136 9 Q96RL7,P83436,Q92538,Q8N2H4,P40616 5 +Pigment granule localization 0.6986333737953898 1.9017960464135648 0.0571978233622227 1.0 0.1521729917386075 5 Q9H267,Q96AX1 2 +Lipid translocation 0.6591489928758979 1.8947396038401412 0.0581269081472393 1.0 0.1538371103318761 4 Q4KMQ2,P08183 2 +Regulation of phosphatidylinositol 3 kinase signaling 0.6968578039478909 1.8934587599741752 0.0582968875685758 1.0 0.1540961028101325 5 Q05086 1 +Receptor mediated endocytosis 0.4588887244291649 1.891865329138176 0.0585089262764175 1.0 0.1544977606338291 47 Q13614,P50570,P41440,Q5VW38,P61978,P11717,Q13432,Q14108,P50897,P02786 10 +Striated muscle cell apoptotic process 0.696231022366555 1.890513981526605 0.0586892524509004 1.0 0.1548140363005232 5 P17655,O95817 2 +Negative regulation of dna templated transcription elongation 0.7061218399223618 1.888649095982698 0.0589388637198917 1.0 0.1552169747101504 9 O14776,Q8IXH7 2 +Striated muscle adaptation 0.657747117502854 1.887823008142403 0.0590497152942095 1.0 0.1553812294892788 4 Q13555 1 +Regulation of transforming growth factor beta activation 0.5713361371724441 1.8866392758194184 0.0592088603069849 1.0 0.1554171967926999 2 P08238 1 +Transforming growth factor beta activation 0.5713361371724441 1.8866392758194184 0.0592088603069849 1.0 0.1554171967926999 2 P08238 1 +Negative regulation of type i interferon mediated signaling pathway 0.6127078336302647 1.8799122892567748 0.0601200327536677 1.0 0.1575508626128414 3 Q14166 1 +Deoxyribonucleoside triphosphate metabolic process 0.7130979795386345 1.875156626348527 0.0607711792078506 1.0 0.1590621717935169 8 Q9H773 1 +Regulation of immune system process 0.3605848644028872 1.8725738897912456 0.0611272496703263 1.0 0.1596031243938052 164 P46379,O94813,P12956,Q00013,Q9HCL2,Q9NZ08,Q9NQT5,Q9UJZ1,P02786,P84095,P49366,P23396,P41440,P28070,Q9NPR9,Q5KU26,Q9GZS3,Q96J02,Q4KMQ2,Q08722,P09601,Q06481,P05771,P07948,P30825,Q9BXW9,Q14166,P46108,P04439,O43290,O15400,O96028,Q96RT1 33 +Positive regulation of voltage gated calcium channel activity 0.5687479780006548 1.872140019265832 0.0611872346711965 1.0 0.1596946963527565 2 O75323 1 +Regulation of cell projection organization 0.3940523658758889 1.8690861779452197 0.0616108257117153 1.0 0.1606040637706773 102 O94813,Q16181,Q32P28,Q9Y4G8,Q14108,P84095,Q16625,Q9NR77,Q13555,Q96PU5,P35241,Q9UQB8,Q8N0X7,Q8WXH0,P08670,P50570,Q9NQX7,P07948,Q92766,P46108,Q05086,Q66K14,Q86X55,Q96G23,P07196 25 +Organophosphate ester transport 0.5209959137470278 1.8684141604897213 0.0617043648006503 1.0 0.1607825115334018 30 Q8TDW0,Q4KMQ2,Q08722,P41440,Q9Y5P4,Q99808,Q14108,Q8WTV0,P08183,Q86VD7 10 +Extrinsic apoptotic signaling pathway via death domain receptors 0.6770180834768426 1.8671247024172333 0.0618841755320513 1.0 0.1611200508369006 11 P09601,O95817,Q13794,Q92974 4 +Defense response to gram positive bacterium 0.6912153712995142 1.86691755356391 0.061913102153793 1.0 0.1611260969190689 5 P60602,Q96EE3 2 +Negative regulation of mrna metabolic process 0.4582279759884197 1.8617990607947803 0.062631418952036 1.0 0.1624716290904699 46 P61978,P98175,Q13247,Q99729,P67809,O75494,Q16629,P07910,P38159,P16989,Q15717,Q14011,Q92804,Q06787,O00422,P35637,O60506,P11940,P18615 19 +Regulation of glucose import 0.719294461610796 1.860533724043612 0.0628100517362428 1.0 0.1627768454883884 7 P31751,Q16625 2 +L aspartate transmembrane transport 0.6521907448988861 1.8603609745958565 0.0628344721337499 1.0 0.1627768454883884 4 Q15758,O75746 2 +Cell adhesion mediated by integrin 0.689739702081402 1.8599645245867216 0.0628905452164851 1.0 0.1628143759441316 5 P07948 1 +Homologous chromosome segregation 0.6750631906401338 1.857320751547629 0.0632655337662269 1.0 0.1636529747544448 11 Q92791,Q9BXW9,P46379,O94901,Q96KQ7 5 +Immune response 0.3548274359303782 1.8536540913361692 0.0637886636269071 1.0 0.1648731184872882 188 P46379,P12956,Q9UQ84,Q9NZ08,Q9NQT5,Q9UJZ1,P02786,P10321,Q9Y5A7,P41440,P07437,P60602,Q96S55,P28070,Q9Y487,Q9NPR9,Q5KU26,Q96J02,P08670,Q08722,Q9Y5P4,P09601,Q06481,O43823,P05771,P07948,Q03518,P46108,O15400,Q96RT1 30 +Regulation of protein folding 0.6882419052852375 1.8529023085171636 0.0638963621788999 1.0 0.1650849180035262 5 Q9H2J4,Q9Y2G5,P08621 3 +Synaptic vesicle exocytosis 0.6181103879215616 1.850615757317562 0.0642248511794463 1.0 0.1656339978699179 15 Q4J6C6 1 +Negative regulation of low density lipoprotein particle clearance 0.6071197411003186 1.8505238483211404 0.0642380840412817 1.0 0.1656339978699179 3 Q92945,P41240 2 +Mast cell activation 0.7168603277503487 1.8493674797588249 0.0644047679282651 1.0 0.1657535378028926 7 P09601 1 +Peptidyl lysine hydroxylation 0.7256936032436183 1.8492557239125265 0.0644208957928611 1.0 0.1657535378028926 6 Q96AY3,Q92791 2 +Positive regulation of t cell mediated cytotoxicity 0.6499202662859371 1.8491173935850749 0.0644408633275048 1.0 0.1657535378028926 4 O15400,P04439 2 +Regulation of t cell mediated cytotoxicity 0.6499202662859371 1.8491173935850749 0.0644408633275048 1.0 0.1657535378028926 4 O15400,P04439 2 +Cytochrome complex assembly 0.6432846786400076 1.8488338867463123 0.0644818025849318 1.0 0.1657535378028926 13 Q6DKK2,Q69YU5,Q7KZN9 3 +Porphyrin containing compound metabolic process 0.6077252848232646 1.8487680403052364 0.0644913140843079 1.0 0.1657535378028926 16 P22830,P09601,P30519,Q7KZN9 4 +Fc receptor signaling pathway 0.6871755089195521 1.8478711593661297 0.0646209836195894 1.0 0.1658872667206921 5 Q06481,Q08722 2 +Fc gamma receptor signaling pathway 0.6871755089195521 1.8478711593661297 0.0646209836195894 1.0 0.1658872667206921 5 Q06481,Q08722 2 +Regulation of receptor catabolic process 0.6477787381214856 1.838500839002792 0.0659886383400625 1.0 0.1687897732481248 4 Q13614 1 +Negative regulation of proteasomal protein catabolic process 0.5509434978878215 1.8360970137792016 0.0663433098856711 1.0 0.1695616492691994 21 Q96HY6,Q8N163,P46379,Q92530 4 +Glycolytic fermentation 0.6040408389845502 1.8342943325180108 0.0666103150001866 1.0 0.1699729773691068 3 Q9NQ88 1 +Fermentation 0.6040408389845502 1.8342943325180108 0.0666103150001866 1.0 0.1699729773691068 3 Q9NQ88 1 +Negative chemotaxis 0.644850101638391 1.8239641825354111 0.0681574873259143 1.0 0.1727518757450022 4 O94813 1 +Establishment of protein localization to mitochondrial membrane 0.5817985336947897 1.820083654732574 0.0687462663711528 1.0 0.1738317820272544 18 P62072,Q9Y584,Q9P0J0,P60602 4 +Cholesterol storage 0.6424985214271045 1.8122768271625351 0.0699434332495958 1.0 0.1762332575196184 4 Q8WTV0 1 +Response to oxygen levels 0.415571537271809 1.8110093184293663 0.0701394092322078 1.0 0.1765188901368089 61 Q15118,P00846,P09601,P30519,P55786,Q13794,O95831 7 +Transforming growth factor beta production 0.6422049840089543 1.8108170131678036 0.0701691818592955 1.0 0.1765245116632984 4 O75787 1 +Regulation of receptor clustering 0.5577483015205523 1.810279232972356 0.0702524958374326 1.0 0.1765592117053414 2 P46109 1 +Regulation of nitric oxide synthase activity 0.7165324265840314 1.8079292279437844 0.0706175160974629 1.0 0.1772350345280882 6 Q8WTV0 1 +Sodium ion transmembrane transport 0.5579757545416815 1.8075909797799352 0.0706701831568086 1.0 0.1772977980568075 20 P50570,Q4KMQ2,P46939,Q96PU5,P27105,P23634,Q9Y6M7 7 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.6889551572837094 1.806571964049996 0.0708290441387013 1.0 0.1776268282195132 9 Q8N163,Q9HBM6,P61978,Q96K76 4 +Triglyceride metabolic process 0.6348997118850509 1.8040793417067849 0.0712188697392075 1.0 0.1784408458627126 13 P50416,Q9BZK7,Q9HCL2,Q8WTV0 4 +Smad protein signal transduction 0.6967221122734755 1.7983831525928522 0.072116310696594 1.0 0.1804315189559594 8 Q9UIQ6,P08670 2 +Positive regulation of translation 0.4210113767909559 1.7977872902638603 0.072210722216385 1.0 0.1805268055409625 56 P16989,Q14011,Q567V2,P67809,P98179 5 +Triglyceride biosynthetic process 0.7053409606561426 1.7963598807300292 0.0724373000826936 1.0 0.1808933869675786 7 Q8WTV0 1 +Import across plasma membrane 0.5559651726276784 1.7947830783341925 0.0726882678927132 1.0 0.1814376157290855 20 P41440,P30825,P23634,P31751 4 +Central nervous system neuron differentiation 0.6327594756375521 1.792626294191047 0.0730326991045093 1.0 0.1821554868715584 13 O94813 1 +Tetrapyrrole metabolic process 0.5662591278183191 1.7904006246176314 0.0733895299855593 1.0 0.1829031443263746 19 Q7KZN9,P09601,P30519,P22830 4 +Regulation of lipid transport 0.6073521414019063 1.7900144737790236 0.0734515846197212 1.0 0.1829866527059514 15 Q9BZF3 1 +Ceramide transport 0.7115129120937806 1.7852163731277355 0.0742262271899663 1.0 0.1844147737549162 6 P08183 1 +Cellular response to exogenous dsrna 0.7018998965882319 1.7804736350310617 0.0749984803627592 1.0 0.1859730209382153 7 P41440 1 +Activation of immune response 0.4561008047326448 1.7786791986980408 0.0752923713942235 1.0 0.1865574412976315 43 P07948,P46379,Q08722,P12956,Q06481,Q9UJZ1,P05771 7 +Chromatin remodeling at centromere 0.635534441205047 1.777587884002437 0.0754715651581405 1.0 0.186929185727852 4 Q6IPU0 1 +Positive regulation of macroautophagy 0.5946610810526731 1.773421401492974 0.0761589052933777 1.0 0.1879778910013675 16 Q8TBX8,P09601,O95817 3 +Peptidyl arginine methylation to asymmetrical dimethyl arginine 0.5923432405419276 1.7723971974940622 0.0763286466848813 1.0 0.1882450771633297 3 Q86X55 1 +Regulation of lipid kinase activity 0.7001177436400534 1.7722367987077283 0.0763552575077468 1.0 0.1882450771633297 7 P07948,Q8TBX8 2 +Regulation of protein polymerization 0.4216065599246181 1.7691698352606489 0.0768655364959247 1.0 0.189208620499937 55 O94813,Q13045,O95429,P23396,Q16625,Q96F07,P28289,P36405,P62993,P45880,Q9UEY8,P35241,Q9UQB8,P35611 14 +Regulation of transmembrane transport 0.4116539393205397 1.7689177717871438 0.0769075979439959 1.0 0.189208620499937 66 P07948,O75844,Q4KMQ2,P50570,Q16625,P31751,P21796,P0CG08,Q06481,Q96PU5,P27105,P23634,P05771,P08183,P28161 15 +Wound healing spreading of epidermal cells 0.6337787218113322 1.7688243451382666 0.0769231926712692 1.0 0.189208620499937 4 Q92766 1 +Regulation of wound healing spreading of epidermal cells 0.6337787218113322 1.7688243451382666 0.0769231926712692 1.0 0.189208620499937 4 Q92766 1 +Protein ufmylation 0.632607854366631 1.762976043500538 0.0779045302309331 1.0 0.1905951168242783 4 Q96HY6 1 +Positive regulation of mrna processing 0.5279341851160775 1.7610945461384688 0.0782224019733575 1.0 0.1908662339738186 22 Q14011,Q96E39,P98179,P52298,P62995,P38159 6 +Positive regulation of response to endoplasmic reticulum stress 0.6884907817425316 1.759581861051817 0.0784787292636681 1.0 0.191327550279763 8 P46379 1 +Negative regulation of protein polymerization 0.5255202624306012 1.7594505794836766 0.0785010073690759 1.0 0.191327550279763 23 O94813,Q13045,P28289,P45880,Q9UEY8,P35241,P35611 7 +Antigen processing and presentation of peptide antigen via mhc class i 0.6684844841527459 1.7547238808617447 0.0793065491697082 1.0 0.1928509029506183 10 Q03518,Q9UIQ6,Q9NZ08,P10321 4 +Lipoprotein catabolic process 0.7046772049037816 1.7542076302795195 0.0793949362579859 1.0 0.1929926209380698 6 P50897 1 +Protein catabolic process 0.3234336595617041 1.7536079350495406 0.0794977104220964 1.0 0.1931691902220007 255 P46379,P49721,Q9P0J0,Q9UL46,Q9NWU2,Q9BZK7,P50897,P04114,O00231,Q96K76,Q16763,Q8NHS3,P17655,Q9Y5A7,Q99436,Q96TA2,Q6IQ22,Q8IXB1,Q5TDH0,P28070,Q96PU5,P35241,O14773,P28074,O95817,Q92530,Q96HY6,Q96J02,Q9UHG3,Q92575,O43464,Q9UIQ6,O75503,P20618,Q13794,Q9UJX3,Q96RL7,Q8N163,P60520,O60502,P51572,Q05086,Q8NBM8,Q16850,Q9H2J4,O43847 46 +Regulation of lamellipodium assembly 0.6101730541970792 1.7532185161577982 0.0795645058943337 1.0 0.1932217519219866 14 Q16625,O94813 2 +Establishment of centrosome localization 0.5886731391585741 1.752901243629408 0.0796189601117025 1.0 0.1932217519219866 3 Q9Y613,P15311 2 +Positive regulation of nuclease activity 0.5885841735649769 1.7524282072584516 0.079700204692938 1.0 0.1932217519219866 3 P23396 1 +Antigen processing and presentation of endogenous antigen 0.7036537742265646 1.7495574292062517 0.0801947109490543 1.0 0.1938160328350715 6 Q03518,Q9NZ08,P10321 3 +Antigen processing and presentation of endogenous peptide antigen 0.7036537742265646 1.7495574292062517 0.0801947109490543 1.0 0.1938160328350715 6 Q03518,Q9NZ08,P10321 3 +Regulation of golgi organization 0.6284565886475594 1.74221548286799 0.0814707457588008 1.0 0.1959978083449889 4 Q13190,P50570 2 +Regulation of inflammatory response to antigenic stimulus 0.6929560320441357 1.7390737379747314 0.0820217934037241 1.0 0.1969875218126159 7 P28070 1 +Regulation of cellular response to growth factor stimulus 0.4960869627368456 1.735343359445222 0.0826800060412453 1.0 0.1979641161663965 32 O94813,P50570,Q96F07,P23634,Q92896 5 +Cellular copper ion homeostasis 0.6628907262312613 1.7326339218456506 0.0831607560115612 1.0 0.1983849817767427 5 P35670,O43819 2 +Cellular response to x ray 0.6992855242060764 1.7296872046614926 0.0836861760062817 1.0 0.199045784118837 6 P12956 1 +Cellular component assembly involved in morphogenesis 0.5667833953767356 1.7289402595316483 0.0838197876525581 1.0 0.1992896286546356 18 Q9NR77,Q13045 2 +Transition metal ion transport 0.5866262044896816 1.726830563381622 0.0841980977524541 1.0 0.1999665826577365 16 Q9HD20,O15173,Q9HC07,P50570 4 +Alcohol catabolic process 0.6719221465944519 1.7245069077522557 0.084616373010026 1.0 0.2007367751201435 9 Q13614,P30837,Q8WTV0 3 +Positive regulation of cellular amide metabolic process 0.4103062031008754 1.723934029396356 0.0847197532626093 1.0 0.2008334387623248 57 P16989,Q14011,Q567V2,P67809,P98179 5 +Neurogenesis 0.3294936266921669 1.719708708742339 0.0854854040132904 1.0 0.2022299878558488 239 Q8WUJ1,Q9H9T3,Q9BRT6,Q13614,O94813,Q9Y4F1,Q32P28,P36405,P55209,Q9Y4G8,Q14108,Q96KQ7,P50897,P42892,P84095,Q9BUP0,Q8NHS3,Q13641,P41440,Q9NR77,Q13555,Q96PU5,Q9UQB8,P23634,Q8N0X7,Q8WXH0,Q9Y6M7,Q92974,P54802,P08670,P50570,O43464,Q96F07,O94901,O75503,Q15375,Q06481,Q96JB5,Q9NQX7,P07948,Q9UBB6,P31751,Q9BSJ2,P46108,Q9NUL3,Q05086,Q86X55,Q96G23,P07196 49 +Response to salt 0.6239164866177203 1.7194650916273355 0.0855297187327934 1.0 0.2022299878558488 4 P52758,P07196 2 +Reactive oxygen species metabolic process 0.4506453830640713 1.7121720782290315 0.0868649614268044 1.0 0.2052581908843707 42 P42785,Q9P0J0,Q13423,P60602,P51790,Q9BTZ2,Q13794 7 +Negative regulation of transforming growth factor beta receptor signaling pathway 0.6777170642558694 1.7085899717875377 0.0875269275288435 1.0 0.2064192808903189 8 Q92896 1 +Protein localization to early endosome 0.6216421127188926 1.7080507008276729 0.0876269352743388 1.0 0.2065791302348334 4 P35241 1 +Negative regulation of cholesterol metabolic process 0.5396311873180268 1.707573571690559 0.0877154956651291 1.0 0.2066359159182204 2 O94905 1 +Negative regulation of alcohol biosynthetic process 0.5396311873180268 1.707573571690559 0.0877154956651291 1.0 0.2066359159182204 2 O94905 1 +Negative regulation of muscle cell apoptotic process 0.6575088713340493 1.7069285380567116 0.0878353357297867 1.0 0.2067662512037947 5 P09601 1 +Postsynaptic signal transduction 0.6210867899235671 1.7052619441162813 0.0881455817662533 1.0 0.2074204034954786 4 P52292,P04899 2 +Bile acid metabolic process 0.6581338426011641 1.703612746333799 0.0884534585923102 1.0 0.2079039373101268 10 Q9BZF3 1 +Inner mitochondrial membrane organization 0.5194105243946705 1.7034234027881314 0.0884888611759624 1.0 0.2079039373101268 22 Q9P0J0,Q13505,P60602,Q5XKP0,Q9Y584,P62072 6 +Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.656997302174179 1.6979868003420775 0.0895102531445315 1.0 0.2097725908970891 10 P46379,P61978 2 +Protein retention in er lumen 0.6195945481917384 1.6977647030488696 0.0895521802765968 1.0 0.2097725908970891 4 O43731 1 +Maintenance of protein localization in endoplasmic reticulum 0.6195945481917384 1.6977647030488696 0.0895521802765968 1.0 0.2097725908970891 4 O43731 1 +Vascular transport 0.6001753806347386 1.6976618004694 0.0895716114026456 1.0 0.2097725908970891 14 P30825,Q15758,P41440,Q99808,P23634,P02786,P08183 7 +Response to retinoic acid 0.6295126202980195 1.6975696682588748 0.0895890116369799 1.0 0.2097725908970891 12 P07948,Q9P0J0,O43464,Q13573,P11717,P02786 6 +Double strand break repair via break induced replication 0.6834897370605775 1.6950879966324426 0.0900587289397487 1.0 0.210580291388502 7 Q14566,Q9BRT9,P33993,P33991,P25205 5 +Regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.6748490341255925 1.6949772108931058 0.0900797439917742 1.0 0.210580291388502 8 P09601,Q92974,Q13794 3 +Sodium ion transport 0.513249171699716 1.6906904669361102 0.0908959359842107 1.0 0.2124108456648891 24 P50570,Q4KMQ2,P46939,Q12955,Q6P4Q7,Q96PU5,P27105,P23634,Q9Y6M7 9 +Regulation of t cell proliferation 0.5803087346274032 1.6900691399182328 0.0910147280097375 1.0 0.2126109353288693 16 Q96J02,P30825,P23396,Q9HCL2,P02786,P49366 6 +Development of primary female sexual characteristics 0.6646372050361518 1.689225378109924 0.0911762473694006 1.0 0.2128548180437854 9 Q05086,P57740,O94813 3 +Peptidyl glutamic acid modification 0.6178864388286807 1.68917685543117 0.0911855429560428 1.0 0.2128548180437854 4 P38435 1 +Phagolysosome assembly 0.617545238185647 1.6874606330569704 0.0915148134699741 1.0 0.213545669582284 4 Q9BZG1 1 +Ubiquitin recycling 0.5759591516429927 1.6850922877122572 0.0919707673897538 1.0 0.2142975714170564 3 Q16763 1 +Positive regulation of t cell proliferation 0.6631624411049142 1.6820700892489495 0.092555249603097 1.0 0.2150103566347181 9 P30825,P23396,Q9HCL2,P02786,P49366 5 +Dendrite morphogenesis 0.4979447677119152 1.676007540158523 0.0937367156929145 1.0 0.2172278913924736 29 Q9UQB8,Q13641,Q05086,Q96PU5 4 +Tail anchored membrane protein insertion into er membrane 0.6598934916866931 1.6661945233680435 0.095674676439684 1.0 0.2205230765833782 9 P46379,Q9NPA0 2 +Regulation of response to interferon gamma 0.5721682847896391 1.6647948988736103 0.0959536820072686 1.0 0.2208985473322854 3 Q15648,P08238 2 +Intrinsic apoptotic signaling pathway by p53 class mediator 0.5560319187928253 1.6632455993912 0.0962632832917154 1.0 0.2214815670853897 18 P46379,P61978,Q13794 3 +Columnar cuboidal epithelial cell maturation 0.5315431899061898 1.6614093638704572 0.0966312584419006 1.0 0.2222484272022186 2 P04818 1 +Negative regulation of proteasomal ubiquitin dependent protein catabolic process 0.5656884535930882 1.661117422975118 0.0966898659018282 1.0 0.2222882522526697 17 Q96HY6,P46379 2 +Roof of mouth development 0.6479183359564731 1.660977674322036 0.0967179306603269 1.0 0.2222882522526697 5 Q6W2J9,Q9NWT1,O95470 3 +Vitamin transport 0.6493462236703551 1.6600445619216218 0.096905488221278 1.0 0.2226394908596389 10 P41440,Q8WTV0 2 +Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.6839900616593393 1.659836778551454 0.0969472926875969 1.0 0.2226557313247927 6 Q8N163,Q96K76 2 +Vesicle mediated transport in synapse 0.4894499624706399 1.6595428633846023 0.0970064508561792 1.0 0.2227118015716721 31 P51790,P50570,Q4J6C6 3 +Cellular metabolic compound salvage 0.6582737168355868 1.6583204370423614 0.0972528061096988 1.0 0.2230668934263332 9 P55263 1 +Negative regulation of plasma membrane bounded cell projection assembly 0.6836452752105826 1.6582574297597137 0.0972655174924495 1.0 0.2230668934263332 6 O94813 1 +Regulation of phosphatidylcholine metabolic process 0.6464621242859602 1.653984858318791 0.0981305892731878 1.0 0.2244896648739059 5 Q8WTV0 1 +Positive regulation of leukocyte cell cell adhesion 0.523187101315792 1.653637959076082 0.0982010952116119 1.0 0.2244896648739059 21 P07948,P30825,P23396,Q08722,O43290,Q9HCL2,P02786,P04439,P49366 9 +Regulation of synapse structure or activity 0.4851719370717017 1.652435140093384 0.0984458769788785 1.0 0.2249690094241038 32 Q9Y4F1,Q13641,P07437,Q9NUL3,Q15375,Q05086,Q9UQB8,P50897 8 +Lamellipodium assembly 0.5640573673658921 1.6513596395175854 0.0986651609850604 1.0 0.2253094698661336 17 Q16625,O94813 2 +Microtubule anchoring 0.6817652311094946 1.64964196174349 0.0990161872112243 1.0 0.2258696654889493 6 Q9P287,O75381,Q14203 3 +Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.5685616644120357 1.6454513361074643 0.0998767703603871 1.0 0.2276707318670275 3 P11940 1 +Regulation of calcium ion import 0.608934930398197 1.6440676349500776 0.1001622324079107 1.0 0.2281509259341811 4 P35222,P14373,P21796 3 +Ensheathment of neurons 0.5424730010706376 1.641662473296409 0.1006599728098114 1.0 0.228967503800884 19 P31751,Q9NR77 2 +Bone mineralization 0.670648573931751 1.635155916523314 0.102016366767186 1.0 0.2318060655716634 7 O75844,Q9UNW1,Q4KMQ2 3 +Skeletal muscle cell differentiation 0.6705139400885392 1.63452599268935 0.1021484530167753 1.0 0.2318997901107493 7 Q9Y5Q8,Q9BYT8 2 +Purine containing compound salvage 0.6704959150805961 1.6344416550046288 0.1021661477804611 1.0 0.2318997901107493 7 P55263 1 +Dna replication synthesis of rna primer 0.606992554224665 1.6342568911439497 0.1022049213360596 1.0 0.2319056799165105 4 Q14181,P49643,P49642 3 +Calcium ion regulated exocytosis 0.6529118010623624 1.6322192004257403 0.1026333173883418 1.0 0.2326306805018638 9 Q9BRK5,Q9NVJ2,P04899 3 +Purine nucleotide transport 0.6025731382018255 1.629868889247033 0.1031292101545768 1.0 0.2335894830709674 13 P41440,Q8TDW0,Q86VD7,Q08722 4 +Trna catabolic process 0.6512881997909222 1.6243050033383235 0.1043107299541277 1.0 0.2359321732554547 9 Q96B26,Q08J23,Q99575 3 +Sodium ion homeostasis 0.67569445587571 1.6217807690582824 0.1048502975208109 1.0 0.2365682531180564 6 Q96PU5 1 +Biomineralization 0.628415808923842 1.620764049711999 0.1050682512961092 1.0 0.2369357990684772 11 O75844,Q13586,Q4KMQ2,Q6W2J9,Q6P4Q7,Q9UNW1 6 +Organonitrogen compound catabolic process 0.3024278799712754 1.6190650289257809 0.1054332722067374 1.0 0.2374656622787024 351 P46379,P49721,Q9P0J0,Q13126,Q9UL46,Q9NWU2,P30519,Q9BZK7,Q9NZ08,P55786,Q8TD30,Q9H773,P50897,P04114,O00231,P42892,Q96K76,P49366,Q16763,Q8NHS3,P17655,Q9Y5A7,Q99436,Q96TA2,Q6IQ22,Q8NCC3,Q8IXB1,Q5TDH0,P28070,Q96PU5,P35241,P23634,O14773,O95470,P28074,O95817,Q92530,Q96HY6,Q96J02,P54802,Q9UHG3,Q92575,O43464,Q9UIQ6,P09601,O75503,P20618,P49902,Q13794,Q8WTV0,Q9UJX3,Q9NRN7,Q96RL7,Q8N163,P60520,O60502,P51572,P09960,Q05086,Q8NBM8,Q96H78,Q9BQT8,Q16850,Q9H2J4,P53004,O43847 66 +Chemokine production 0.6587721845144572 1.6183834046681578 0.1055799961960071 1.0 0.2377126012000019 8 P09601 1 +Regulation of lysosomal lumen ph 0.667019318212822 1.6181643389090026 0.1056271858863311 1.0 0.2377353446388281 7 O75787,O75503,Q96AX1,Q9HC07,P50897 5 +Cap dependent translational initiation 0.5231316725978721 1.6132045071691266 0.1067000845717158 1.0 0.2398974191878985 2 Q04637 1 +Mitotic g2 m transition checkpoint 0.5758859489853675 1.6109250815966094 0.1071960525135085 1.0 0.2405302311896178 15 Q68E01,P53350,Q13564,Q9Y619,P38398,Q96JB5,P06493,Q9NXR7 8 +Lysine metabolic process 0.6023713396619595 1.6108841541109034 0.1072049743665317 1.0 0.2405302311896178 4 Q9BQT8 1 +Endocrine process 0.6372171255821637 1.609496286332037 0.1075078663885074 1.0 0.2409682703266996 5 P42892,Q6WKZ4 2 +Cellular extravasation 0.6369804914170482 1.608355480107018 0.107757346198742 1.0 0.2413832501345734 5 Q08722 1 +Leukotriene metabolic process 0.6014427107817675 1.6061821555450528 0.1082338929170096 1.0 0.2419035054386444 4 P09960 1 +Ribonucleoprotein complex localization 0.663372548349466 1.6010679546110058 0.1093618689082878 1.0 0.243829419026826 7 Q08J23,Q9ULX6 2 +Ventricular system development 0.6702812698146299 1.5968854755891226 0.110291237973551 1.0 0.2455598594687259 6 Q9H6E4 1 +Interleukin 17 production 0.5202199935296119 1.5964738548696096 0.1103830384991657 1.0 0.2456789155484904 2 P35232 1 +Positive regulation of protein kinase activity 0.4465907065011654 1.5954959145263945 0.1106013828706995 1.0 0.2460254829605485 40 P12956,Q99627,Q13432,Q9Y4G8,P23634,P14635 6 +Negative regulation of nervous system development 0.5731848326177278 1.5954326772977196 0.1106155135557411 1.0 0.2460254829605485 15 Q8N0X7,Q96G23,Q06481,Q9Y4G8 4 +Organic hydroxy compound catabolic process 0.6346467898636197 1.5868249260355751 0.1125523017887253 1.0 0.2496080459670581 10 Q13614,P30837,Q8WTV0 3 +Mitochondrial fragmentation involved in apoptotic process 0.6666004614186964 1.5799301525703515 0.1141228630901249 1.0 0.2527738605417073 6 Q8N163,Q9Y3D6 2 +Sterol homeostasis 0.607119625163333 1.5797011058316732 0.1141753322738845 1.0 0.2528027218913989 12 O15118,Q5BJF2,Q8WTV0 3 +Leukocyte mediated immunity 0.4334915364540332 1.578443483693864 0.1144637621851287 1.0 0.2532663843999569 43 P07948,Q9NVJ2,P07437,Q7Z434,P09601,P46108,Q9UQ84,O15400,O96028,Q9NQT5,Q9NUQ9,P02786,P04439 13 +Positive regulation of rna splicing 0.4991283706755967 1.5781760311775042 0.1145251750812861 1.0 0.2533148282508778 23 Q14011,Q13573,Q9NW64,Q96E39,P98179,O75312,P62995,Q8WVV9,P38159 9 +Response to acid chemical 0.4976880573171124 1.5682129109676444 0.1168314522803293 1.0 0.258059823954828 23 Q15388,P07948,Q99729,P17655,Q6IAA8,Q9P2J5,P23634,Q9UQB8,O95831 9 +Regulation of er associated ubiquitin dependent protein catabolic process 0.5523947639682404 1.5583682243747154 0.1191459846245672 1.0 0.2623314483159851 3 P51572 1 +B cell receptor signaling pathway 0.5919131386700967 1.5578316141338262 0.1192731696612541 1.0 0.2624550790355152 4 P05771 1 +Positive regulation of erk1 and erk2 cascade 0.5893061359828197 1.557665123558588 0.1193126521543668 1.0 0.2624550790355152 13 Q13641,Q9Y4G8,P04899 3 +Regulation of cell cell adhesion 0.4308452019667588 1.554819838996685 0.1199889828560096 1.0 0.263671367880364 43 P07948,Q96J02,P30825,Q92990,P55196,P23396,P41440,Q08722,Q15375,O43290,Q9HCL2,P35241,Q9NUQ9,P02786,P04439,P49366 16 +Negative regulation of proteolysis involved in cellular protein catabolic process 0.4867564796383885 1.5543233142763004 0.1201073150106539 1.0 0.2638409490124372 27 Q96HY6,Q8N163,P46379,P60520,Q92530 5 +Purine containing compound transmembrane transport 0.6269975237631962 1.5485637964721004 0.121486614558008 1.0 0.2662322048946432 10 P41440,Q8TDW0,Q86VD7 3 +Positive regulation of mrna splicing via spliceosome 0.5464636531218374 1.5456553948021952 0.122187815182041 1.0 0.2673119096644651 17 Q14011,Q96E39,P98179,P62995,P38159 5 +Cellular response to oxygen levels 0.4566607925206978 1.5417779199509836 0.1231275693934483 1.0 0.2680318168239449 36 Q15118,P09601,P55786,Q13794,O95831 5 +Establishment of protein localization to organelle 0.3396364452521348 1.5403430508162788 0.1234767551324937 1.0 0.2685734646756991 168 P46379,Q9P0J0,O95429,O60830,Q9NS69,Q5JRX3,Q99595,P55786,Q14108,Q9Y3D6,Q15388,Q8N4H5,O00459,Q9UI26,Q8WWC4,P60602,O43681,O95831,O95817,O43464,O75381,Q9UFC0,Q9Y584,Q06481,Q99567,Q96RL7,O95071,P51572,P20645,Q9Y2T2,P57740,P62072,Q10713,Q96P70 34 +Myoblast fusion 0.6571233964923198 1.53617716605271 0.1244949346398942 1.0 0.2705127223870244 6 P41440,P17655 2 +Syncytium formation 0.6571233964923198 1.53617716605271 0.1244949346398942 1.0 0.2705127223870244 6 P41440,P17655 2 +Regulation of neurotransmitter levels 0.4828392310181573 1.525981217837147 0.127014542129757 1.0 0.2745410610001096 27 P41440,Q4J6C6,Q99808,P50897,P05771 5 +Regulation of rac protein signal transduction 0.5856480707495496 1.5259500402828794 0.1270223070914111 1.0 0.2745410610001096 4 P50570 1 +Peptidyl proline hydroxylation 0.654532375274399 1.5241915013230984 0.1274608804082464 1.0 0.2753704898607548 6 Q32P28,O75718 2 +Regulation of lipophagy 0.5076027175671398 1.5237254316788909 0.1275773137609563 1.0 0.2754624226929666 2 O15270 1 +Phosphatidic acid metabolic process 0.6383350795697581 1.5203597578866874 0.1284205826686326 1.0 0.2768839337053264 8 Q9NPH0 1 +Negative regulation of vascular endothelial growth factor receptor signaling pathway 0.5069556777741916 1.5199843191509093 0.1285149167412502 1.0 0.2768887790453282 2 P18031 1 +Axon development 0.3877400286491626 1.51996679792377 0.1285193205021393 1.0 0.2768887790453282 59 O94813,P50570,P41440,Q8N0X7,Q06481,Q9UQB8,Q96G23,P42892,P84095,P07196 10 +Actin filament polymerization 0.4497893093601697 1.5171190326996356 0.129236633748272 1.0 0.2780821827211895 37 O94813,Q13045,O95429,Q96F07,Q9UEY8,Q9UQB8 6 +Cell morphogenesis involved in neuron differentiation 0.3859334887335769 1.516784139637561 0.1293211926927719 1.0 0.2781707534096203 78 Q9Y4F1,O94813,Q13641,P50570,P41440,Q05086,Q8N0X7,Q06481,Q15375,Q96PU5,Q9Y4G8,Q9UQB8,P42892,P84095,P07196 15 +Postsynaptic cytoskeleton organization 0.5837123180610847 1.5160849727009071 0.1294978675940998 1.0 0.2783639608578739 4 P07196 1 +Adherens junction maintenance 0.5059851180847675 1.5143708262053686 0.1299318142343692 1.0 0.2791095607380385 2 Q96AC1 1 +Cell cell junction maintenance 0.5059851180847675 1.5143708262053686 0.1299318142343692 1.0 0.2791095607380385 2 Q96AC1 1 +Regulation of lipid localization 0.5018765029131843 1.5117881346622282 0.1305877688588581 1.0 0.2802057362124331 21 Q9BZF3,Q8WTV0 2 +Regulation of receptor mediated endocytosis 0.5017501835932981 1.5109432880773326 0.1308029005985722 1.0 0.2802902199305773 21 Q13614,P50570,P41440,P61978,P50897 5 +Lysosomal lumen acidification 0.6167764987200437 1.510592218626822 0.1308923777337933 1.0 0.2802902199305773 5 O75787,O75503,P50897 3 +Intrinsic apoptotic signaling pathway 0.3861895687338164 1.510410626005683 0.1309386789027655 1.0 0.2802902199305773 76 Q8N163,P16989,Q9P0J0,P46379,Q9HBM6,Q15118,P23396,O43464,P51572,P09601,P61978,Q8IXB1,P45880,Q13794,O95831,Q9Y3D6,Q96K76 17 +Negative regulation of actin filament polymerization 0.5312100285032496 1.510325082208326 0.130960494640308 1.0 0.2802902199305773 18 O94813,Q13045,P28289,Q9UEY8,P35241,P35611 6 +Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules 0.5050145583953518 1.5087551634272198 0.1313613626630125 1.0 0.2804884525882741 2 P98194 1 +Enteroendocrine cell differentiation 0.5050145583953498 1.5087551634272076 0.1313613626630156 1.0 0.2804884525882741 2 O00330 1 +Synaptic vesicle clustering 0.5050145583953425 1.508755163427166 0.1313613626630263 1.0 0.2804884525882741 2 P35222 1 +Detection of muscle stretch 0.5050145583953425 1.508755163427166 0.1313613626630263 1.0 0.2804884525882741 2 P35222 1 +Negative regulation of neuron projection development 0.4908408889944862 1.508254560805777 0.1314893879522722 1.0 0.2806683239340876 22 P08670,Q9NR77,Q05086,Q96G23,Q8N0X7,Q86X55,Q9NQX7 7 +Organic hydroxy compound transport 0.4721777906096096 1.5066272490337924 0.1319062287877919 1.0 0.2814643563680912 30 O15118,Q9BZF3,Q9P260,Q8WTV0 4 +Neuron cellular homeostasis 0.6505583052307438 1.5057891263322405 0.1321213155826823 1.0 0.2817357394826992 6 P51790 1 +Response to endoplasmic reticulum stress 0.3806979582490061 1.5022533760185657 0.1330316847097379 1.0 0.2834883972704189 85 Q7Z2K6,Q96HY6,P46379,P41440,Q92575,Q13794,O95831 7 +Cell activation 0.3430443371304251 1.5007407050531214 0.1334226404291989 1.0 0.2839439326531093 120 P46379,P12956,Q9UQ84,P0CG08,Q9HCL2,Q9NQT5,Q9UJZ1,P02786,P49366,P24390,Q96J02,Q08722,P09601,P05771,P07948,P30825,Q9BXW9,O43290,P78318 19 +Adaptive immune response 0.4392963110725728 1.4967148224838815 0.1344674777429537 1.0 0.2857879749112512 39 P07948,Q03518,Q9UQ84,O15400,Q9NZ08,O96028,Q9NQT5,P02786,P05771,P10321 10 +Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.6482338339093491 1.4950150317684368 0.134910519165436 1.0 0.2866345468513242 6 P09601,Q92974 2 +Positive regulation of cell adhesion 0.4003172401930754 1.4936550530508406 0.1352658020971082 1.0 0.2872941654878939 53 P07948,P30825,Q92766,P23396,O95429,P41440,P50570,Q08722,Q53GQ0,P46939,P46108,O43290,Q9HCL2,P02786,P04439,P49366 16 +Negative regulation of transmembrane transport 0.528326463578492 1.4924578801610204 0.135579151241326 1.0 0.2876737369933465 18 P31751,P21796,Q06481,Q96PU5,P05771 5 +Regulation of endocytosis 0.438594302275906 1.4907635916905675 0.136023573725234 1.0 0.2885212136263236 39 Q13614,P50570,P41440,P61978,Q13432,Q96PU5,P50897 7 +T cell activation 0.4025918045456708 1.488554892454286 0.1366046172146628 1.0 0.2890840529369393 52 P07948,Q96J02,P30825,Q9BXW9,P23396,Q08722,P24390,P17812,P0CG08,O43290,Q9HCL2,P35579,Q9UJZ1,Q9NUQ9,P02786,P04439,P49366 17 +Cation transport 0.3372997241760076 1.485922658545689 0.1372995794935336 1.0 0.2902672508422001 158 Q9HD20,Q70HW3,P21796,O43772,Q9HC07,Q9UJZ1,P02786,O15173,Q13555,Q96PU5,P23634,P13073,P04899,Q9Y6M7,P50570,P00846,Q4KMQ2,P27105,Q99808,P05771,Q86VD7,P07948,P28161,P30825,O75844,Q15758,Q13423,Q7KZN9,Q9Y619,P51790 30 +Organism emergence from protective structure 0.645996681417288 1.484638616138996 0.1376395802882817 1.0 0.2908901119841364 6 Q9BZK7,O43678,Q12824 3 +Positive regulation of cytoplasmic translation 0.6014832660901551 1.482134070650888 0.1383046248140149 1.0 0.2920395318322822 11 P67809,O60506,P16989 3 +Dephosphorylation 0.3853189124474739 1.4820205457487148 0.1383348282076328 1.0 0.2920395318322822 68 Q13614,Q8TF05,Q86XL3,Q5TFE4,O95429,Q99956,Q13555,Q969T7,P49902,Q9UNW1,Q10713,Q9NPH0,Q6PIU2,P04899,P78318 15 +Positive regulation of protein autophosphorylation 0.57674758073567 1.48053706057519 0.1387299779374635 1.0 0.29247177586567 4 Q92878 1 +Chemical synaptic transmission postsynaptic 0.630018436320849 1.4802797010524429 0.1387986181253304 1.0 0.29247177586567 8 Q9UQB8 1 +Regulation of postsynaptic membrane potential 0.630018436320849 1.4802797010524429 0.1387986181253304 1.0 0.29247177586567 8 Q9UQB8 1 +Steroid biosynthetic process 0.4113205538730842 1.4746148523718514 0.1403161195519393 1.0 0.2951842226215724 48 Q9BZF3,Q9UHQ9,Q53GQ0,P48449,Q9H3P7,P14324,Q15392,Q16850,P04114,Q15800 10 +Protein o linked glycosylation via serine 0.5368932038834996 1.474340191384789 0.1403900189167484 1.0 0.2952427891261014 3 Q6UW63,Q10471 2 +Regulation of protein targeting 0.4817059837730377 1.4703917927644334 0.1414556729035436 1.0 0.2971913678504473 24 O95429,O43464,P31751,P55786,P27105,O95817 6 +Regulation of bone mineralization 0.6082963355942471 1.4693607713511947 0.1417349615465197 1.0 0.2976805712690668 5 O75844,Q4KMQ2 2 +Cellular response to ether 0.4978971206729227 1.4675094640374886 0.1422375166485026 1.0 0.2985404327822206 2 P11802 1 +Cellular modified amino acid catabolic process 0.6272572484762873 1.4669505468052175 0.1423895086832098 1.0 0.2987616205104338 8 Q8NBM8,Q9UHG3 2 +Urogenital system development 0.4355558275587103 1.464981779265396 0.1429258889963987 1.0 0.2995928543057278 39 O75844,P46379,O94813,Q15375,Q05086,P57740,O95470,P80723 8 +Lymphocyte mediated immunity 0.4665681728968855 1.4644625111347531 0.1430676189565518 1.0 0.2997919050380835 30 Q9NVJ2,P07437,P46108,Q9UQ84,O15400,O96028,Q9NQT5,Q9NUQ9,P02786,P04439 10 +Regulation of cell activation 0.3833272378537888 1.463037853399489 0.1434570213829391 1.0 0.3002512149376752 63 P07948,Q96J02,P30825,Q9BXW9,P23396,Q08722,P12956,P09601,O43290,Q9HCL2,O96028,Q9NQT5,P02786,P49366 14 +Regulation of postsynapse organization 0.5324666641710413 1.4610207352958058 0.1440097510874767 1.0 0.3010771377921479 17 Q05086,Q9UQB8,Q15375 3 +Reticulophagy 0.5728117624895609 1.46041294246107 0.1441766178916992 1.0 0.301229504786764 4 Q96HY6 1 +Regulation of sodium ion transmembrane transport 0.5577743859627151 1.459373995157842 0.1444621994050399 1.0 0.3016295433831615 14 P27105,P23634,P50570,Q96PU5 4 +Protein localization to endoplasmic reticulum 0.4457563691643505 1.4532671266865802 0.1461496008138247 1.0 0.3045575231523462 36 Q96HY6,P46379,Q8NBM4,P24390,P60520,P51572,Q92538,P37108,O15027,O43681,O43731 11 +Regulation of t cell activation 0.4559958617925266 1.4527754351379487 0.1462861144930036 1.0 0.3046439226446242 33 P07948,Q96J02,P30825,Q9BXW9,P23396,Q08722,O43290,Q9HCL2,Q9NUQ9,P02786,P04439,P49366 12 +Cellular ion homeostasis 0.3707700321797954 1.4506516228479682 0.1468768927652253 1.0 0.3055042395830377 92 Q9HD20,P0CG08,Q9HC07,P50897,Q9UJZ1,P02786,Q9Y3D6,Q96AX1,Q9Y487,Q96PU5,P23634,Q9Y6M7,P09601,O75503,P05771,P28161,P07948,O43819,P51572,P51790,Q05086,Q93050 22 +Cellular response to potassium ion 0.4949854416046662 1.4506050440426057 0.1468898699524059 1.0 0.3055042395830377 2 P55011 1 +Response to potassium ion 0.4949854416046662 1.4506050440426057 0.1468898699524059 1.0 0.3055042395830377 2 P55011 1 +Positive regulation of receptor internalization 0.5323624595469276 1.4496931621025753 0.1471441034190768 1.0 0.3059337343225047 3 Q06787,Q96CW1 2 +Negative regulation of transport 0.3820665586302432 1.4488813935894815 0.1473707081186359 1.0 0.3062062363178141 71 Q13614,O95429,Q08722,P31751,P09601,P21796,Q6WKZ4,Q13432,Q06481,Q96PU5,P05771,Q16850,P53367,P04899,O95817 15 +Positive regulation of cell projection organization 0.3983984424978154 1.4470824764658436 0.1478738253050857 1.0 0.3070525494673145 52 P07948,O94813,Q92766,P50570,Q16181,Q32P28,Q16625,Q9Y4G8,Q14108,Q9UQB8 10 +Epithelial cell maturation 0.5317152103559917 1.4461691681588622 0.1481297591671184 1.0 0.3074027458133102 3 P15121,P04818 2 +Cytosolic transport 0.3804881382803892 1.4459673952418317 0.1481863470457298 1.0 0.3074027458133102 58 Q13614,Q4J6C6,Q14203,P15311,P40616,O75494,P42566,P14373,P35241,O60749,Q13190,O95249,Q9NVJ2,O75503,Q8N2H4,Q93009,P53367,Q96RL7,O14976,Q92538,O60499 21 +Neurotrophin signaling pathway 0.6032809082275141 1.444925599493595 0.1484787848743556 1.0 0.307909741522038 5 Q9Y4G8 1 +Chromosome organization involved in meiotic cell cycle 0.520389770525081 1.443183348029282 0.1489688290903785 1.0 0.3086264364800667 18 Q92791,Q9BXW9,P46379,O94901,Q96KQ7,Q9NTJ3 6 +Layer formation in cerebral cortex 0.5691162188410432 1.4414950826204964 0.1494448655585554 1.0 0.3090426720776412 4 P35222,P43034,Q96N66 3 +Nucleotide transmembrane transport 0.5936157145494396 1.4414018046556312 0.1494712007400531 1.0 0.3090426720776412 11 P41440 1 +Clathrin dependent endocytosis 0.5545514413021067 1.441108201231594 0.1495541169532517 1.0 0.3090426720776412 14 Q5VW38,P50570 2 +Positive regulation of cell activation 0.4326727673920845 1.4404847862919687 0.1497302912325464 1.0 0.3092046284795821 39 P07948,P30825,P23396,Q08722,P12956,O43290,Q9HCL2,O96028,Q9NQT5,P02786,P49366 11 +Regulation of mrna export from nucleus 0.6364130392495881 1.440112736606758 0.1498355062246021 1.0 0.3093222527857326 6 Q08J23 1 +Ion homeostasis 0.3563553310874285 1.4394661463375544 0.1500184949725198 1.0 0.3095401501011255 107 Q9HD20,P30519,P0CG08,Q9HC07,P50897,Q9UJZ1,P02786,Q9Y3D6,Q96AX1,Q9Y487,Q96PU5,P23634,P04899,Q9Y6M7,P09601,O75503,P05771,P28161,P07948,O43819,P51572,P51790,Q05086,Q93050 24 +Regulation of dendritic spine morphogenesis 0.5806036315291965 1.4388451731192415 0.1501943943499495 1.0 0.3096642225098669 12 Q9UQB8 1 +Regulation of lamellipodium organization 0.5367209804621944 1.433669003422424 0.1516667417001007 1.0 0.3120975326798221 16 Q16625,O94813,P50570 3 +Positive regulation of protein metabolic process 0.2887477677881243 1.4333498033664207 0.1517578958554435 1.0 0.3121848884574432 301 P46379,Q9P0J0,Q567V2,Q9UL46,O95429,P12956,Q71RC2,Q9Y4G8,Q03164,P02786,Q9Y3D6,Q16763,Q9Y5A7,P23396,P41440,P67809,Q99627,Q13432,P98179,Q96PU5,P35241,P23634,Q96M27,Q13190,O95831,Q92974,Q9BTE7,Q96HY6,Q9Y3Y2,P16989,Q96J02,Q14011,P08670,Q86XL3,Q9GZS3,O43464,Q96F07,Q15375,O43823,Q13794,Q96JB5,P14635,Q12824,P07948,Q96A26,P31751,P51572,Q9ULX6,Q05086,O95816,Q9UHR5,O60506,Q96P70,P11940,O43847 55 +Cellular response to ionizing radiation 0.5086145242871853 1.427106882378158 0.1535490890175692 1.0 0.3153635567454723 19 O75844,P50570,P12956,Q9H1E3,P62993,Q9NXR7 6 +Regulation of lymphocyte activation 0.4014966677186476 1.4268137985814526 0.1536335727760129 1.0 0.3153695720803603 50 P07948,Q96J02,P30825,Q9BXW9,P23396,Q08722,P12956,O43290,Q9HCL2,O96028,Q9NQT5,P02786,P49366 13 +Mitochondrial electron transport cytochrome c to oxygen 0.6334263219354224 1.4262128414064614 0.1538069140290758 1.0 0.3154887420564404 6 P13073,Q7KZN9 2 +Regulation of leukocyte degranulation 0.5987488902839481 1.4228159294426583 0.1547895223392434 1.0 0.3173011954571636 5 P09601 1 +Golgi vesicle transport 0.3335807936113341 1.4219290354406608 0.1550468531387829 1.0 0.3176255444613611 130 Q8WU17,Q96PC5,Q6NUQ1,Q4J6C6,O75396,P36405,O15027,Q92734,P40616,O14653,Q5BJH7,P24390,Q9Y2D4,Q12955,O60826,O60749,Q13190,Q8TBA6,Q9H5V9,P50570,Q14746,O94979,O15127,Q12981,Q9UP83,Q9P2W9,Q9Y2V7,O15126,Q96RL7,P83436,Q9BZG1,P60520,Q92538,P51572,Q9Y282,O60499,Q8NHH9,O43731 38 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.5771475505730244 1.4203983527356527 0.1554917421114865 1.0 0.3183334611736278 12 P50570,Q92896 2 +Phosphatidylcholine metabolic process 0.5343248583623944 1.4194536580308077 0.1557667983461377 1.0 0.3186241877185571 16 Q8WTV0,Q8NCC3 2 +Dendritic spine morphogenesis 0.5503983885176902 1.4175445435872465 0.1563237807914719 1.0 0.3194247481266608 14 Q9UQB8 1 +Negative regulation of catabolic process 0.3608008246934024 1.4164661806951624 0.1566390591502995 1.0 0.3198650427376298 101 Q13614,Q96HY6,P16989,P46379,Q14011,P67809,P09601,O15118,Q92804,P23634,Q16850,Q08J23,Q92530 13 +Adult locomotory behavior 0.5501664188577683 1.4162275413940455 0.1567088946621349 1.0 0.3199057371924473 14 O75844,O43464,P51790,O15118,P50897 5 +Regulation of sodium ion transport 0.5336342966430241 1.415354880808509 0.1569644714724303 1.0 0.3202235080007251 16 P50570,P46939,Q12955,O43865,P27105,Q96PU5,P23634 7 +Regulation of receptor internalization 0.6004182938036909 1.4148684707415338 0.1571070638648013 1.0 0.3204124337809025 10 P41440 1 +Positive regulation of leukocyte proliferation 0.5630116666429948 1.4135332302300283 0.1574989978466359 1.0 0.3211095980270153 13 P07948,P30825,P23396,Q9HCL2,P02786,P49366 6 +Positive regulation of oxidoreductase activity 0.6079684798048006 1.4115025020262053 0.1580964983857566 1.0 0.3221228717904323 9 Q8WTV0 1 +Copper ion homeostasis 0.6300243137155153 1.4103674425434052 0.158431213675406 1.0 0.322630135717435 6 P35670,Q8N668,O60826,O43819 4 +Mesonephros development 0.6299363612012363 1.4099576141388792 0.1585521988510376 1.0 0.3226411411540163 6 O94813 1 +Response to nerve growth factor 0.6067162736786579 1.4053101135885595 0.1599290822551176 1.0 0.3250302527759365 9 Q05086,Q9Y4G8 2 +Regulation of potassium ion transmembrane transporter activity 0.6066677949840769 1.405070338701399 0.1600003632240838 1.0 0.3250720533332416 9 Q96PU5 1 +Outer mitochondrial membrane organization 0.5949056765961301 1.404045772374545 0.1603052198937113 1.0 0.3255882317866571 5 Q9NS69,O14737 2 +Regulation of response to endoplasmic reticulum stress 0.4719666679989256 1.4017606786409604 0.1609867241193887 1.0 0.3266618871811592 24 P46379,Q13794 2 +Positive regulation of ubiquitin protein ligase activity 0.5233897414608291 1.4007778734246854 0.1612805072494705 1.0 0.3270509495315109 3 Q16763 1 +Positive regulation of tor signaling 0.5939166473831585 1.3992124153434615 0.16174929462428 1.0 0.3278978426760388 5 Q6IAA8,Q96EE3,Q9P2J5 3 +Growth plate cartilage development 0.5206816374253588 1.385989388374556 0.1657501437973052 1.0 0.3342115198932767 3 O75844 1 +Bone growth 0.5206816374253588 1.385989388374556 0.1657501437973052 1.0 0.3342115198932767 3 O75844 1 +Regulation of leukocyte proliferation 0.4829386917314552 1.384676525893972 0.1661514000046424 1.0 0.334809957255504 21 P07948,Q96J02,P30825,P23396,Q9HCL2,P02786,P49366 7 +Negative regulation of cellular response to growth factor stimulus 0.5935252277842078 1.38003176417161 0.1675768649647802 1.0 0.3371524495995734 10 O94813,P23634 2 +Diadenosine polyphosphate metabolic process 0.5190938511326907 1.3773137433520737 0.1684152679701349 1.0 0.3379905659638588 3 Q9BW91,Q15046 2 +Barbed end actin filament capping 0.6009904713294573 1.3769710514181868 0.1685211981240988 1.0 0.3380973020267522 9 Q9UEY8,Q13045 2 +Negative regulation of cellular catabolic process 0.3663427302838165 1.372536127534439 0.1698966002090427 1.0 0.3404734808760701 90 Q13614,Q96HY6,P16989,P46379,Q14011,P67809,P09601,O15118,Q92804,P23634,Q08J23,Q92530 12 +Activated t cell proliferation 0.5883946183678215 1.3722052769637945 0.1699995431439249 1.0 0.3405303348601746 5 Q9HCL2 1 +P38mapk cascade 0.4813976059527745 1.3715032804087115 0.1702181216140814 1.0 0.3407552028564216 2 P15311 1 +Regulation of p38mapk cascade 0.4813976059527745 1.3715032804087115 0.1702181216140814 1.0 0.3407552028564216 2 P15311 1 +Regulation of myeloid leukocyte mediated immunity 0.6071404105519217 1.3695414313572596 0.1708300931217499 1.0 0.3415536172521575 8 P07948,P09601 2 +Cation transmembrane transport 0.33096510226397 1.3638595946656065 0.1726117597073215 1.0 0.3444061774372245 122 Q9HD20,Q70HW3,P21796,O43772,Q9HC07,Q96PU5,P23634,P13073,Q9Y6M7,P50570,P00846,P27105,P07948,P30825,Q15758,Q13423,Q7KZN9,Q9Y619,P51790 19 +Regulation of actin filament length 0.42364216065382 1.3635576467108703 0.1727068296364367 1.0 0.3444061774372245 39 O94813,Q13045,O95429,Q96F07,Q9UEY8,Q9UQB8 6 +Negative regulation of ion transmembrane transporter activity 0.6057495049659887 1.3627890694954887 0.1729489969582607 1.0 0.3447148851064835 8 Q12955,Q96PU5,P28161 3 +Cellular hormone metabolic process 0.4890866362961089 1.361513689478218 0.1733514103834235 1.0 0.3453042965461806 20 Q9HB40,Q53GQ0,Q9BTZ2,O95470,P42892 5 +Alcohol metabolic process 0.3696507641601447 1.3605874462763003 0.173644101016352 1.0 0.3456009543295586 84 Q13614,P49748,P04114,P48735,P48449,P61457,O15118,Q15392,Q9BTZ2,Q9UNW1,Q8WTV0,Q16850,Q10713,P30837,Q15800,O60762 16 +Regulation of transcription elongation from rna polymerase ii promoter 0.515317239454051 1.356782860241403 0.1748502150813942 1.0 0.3473809343082634 17 P35269,O14776,Q8IXH7 3 +Negative regulation of rna catabolic process 0.4436103099697186 1.3557219432300536 0.1751876549462663 1.0 0.3478788315382798 33 Q99729,P16989,Q15717,Q14011,P67809,Q9H814,Q92804,Q06787,P07910,P98175,O60506,Q08J23,P11940 13 +Negative regulation of axonogenesis 0.5847548736451063 1.3543854993308595 0.1756134214039713 1.0 0.3486162995352914 5 Q15375,Q8N0X7 2 +Positive regulation of cell junction assembly 0.588247731359788 1.353322019536008 0.1759527776135294 1.0 0.3491818280194191 10 Q13641 1 +Positive regulation of carbohydrate metabolic process 0.61092506402022 1.3529946168037597 0.1760573501484033 1.0 0.349281217719364 7 Q13794 1 +Nucleotide transport 0.5229730435260164 1.351975317122163 0.1763832114951355 1.0 0.349697131239957 16 P41440,Q8TDW0,Q86VD7,Q08722 4 +Positive regulation of phospholipase activity 0.5839947187124064 1.3506621208689535 0.1768036914880497 1.0 0.3503243824206125 5 P35232,P40616,Q14344 3 +Modification of postsynaptic structure 0.610340425203847 1.350210225038342 0.1769485592610125 1.0 0.3503243824206125 7 Q9UQB8 1 +Regulation of dna binding transcription factor activity 0.3718823818721552 1.3499862730530352 0.1770203860624593 1.0 0.3503243824206125 59 Q96HY6,Q96J02,P60900,Q9BXW9,P23396,P41440,O75381,P09601,Q96RT1,Q96JB5,Q12824,P02786,P05771,Q92974 14 +Fc receptor mediated stimulatory signaling pathway 0.6169904702282579 1.3495451873677524 0.1771619163931181 1.0 0.3504962605184838 6 Q06481,Q08722 2 +Cell part morphogenesis 0.3529737301126712 1.3493527953605469 0.1772236752473286 1.0 0.350510261751119 104 Q9BRT6,O94813,Q9Y4F1,O00429,Q9Y4G8,P42892,Q9Y3D6,Q8IZP0,P84095,Q13641,Q9HCE1,P41440,O00264,Q96PU5,Q9UQB8,O60749,Q8N0X7,P50570,Q9Y5P4,Q96F07,Q15375,Q06481,Q9BPU6,Q92766,Q9NUL3,Q05086,Q9BVA1,P07196 28 +Macromolecule catabolic process 0.2932031397245813 1.3487506479357578 0.1774170714006189 1.0 0.3506150018195945 395 Q13614,P46379,P49721,Q9P0J0,Q9UL46,Q9Y3B2,Q9NWU2,Q7L8L6,Q9BZK7,Q96B26,P50897,P04114,O00231,Q08J23,Q9NQT5,Q96K76,Q16763,Q8NHS3,P17655,Q9Y4Y9,Q9Y5A7,Q99436,P67809,Q96TA2,Q6IQ22,Q8IXB1,Q5TDH0,P28070,Q96PU5,P35241,O14773,O95831,P28074,Q99575,O95817,Q92530,Q96HY6,Q96J02,P16989,Q92879,Q14011,Q9UHG3,P08670,P54802,Q92575,O43464,Q9UIQ6,O75503,Q969T7,P20618,Q92804,Q13794,Q9UJX3,Q96RL7,Q8N163,Q9H814,P60520,O60502,P51572,Q05086,Q8NBM8,P52298,Q16850,Q9H2J4,O43847 65 +Meiotic chromosome segregation 0.4677367061200202 1.3486770259152716 0.1774407279099477 1.0 0.3506150018195945 22 Q92791,P46379,Q9BXW9,P53350,O94901,Q96KQ7,Q9NTJ3 7 +Actin polymerization or depolymerization 0.4060547948004051 1.348108448142897 0.1776235046262428 1.0 0.3508680014342733 44 O94813,Q13045,O95429,Q96F07,Q9UEY8,Q9UQB8 6 +Cellular response to retinoic acid 0.6021826906044003 1.3454645236336265 0.1784752704326719 1.0 0.3522787228743724 8 P07948,O43464,Q9P0J0 3 +Response to reactive oxygen species 0.4420386327761845 1.3433760694020127 0.1791502316925655 1.0 0.3531220741541651 33 Q99720,O95831,P60602,P09601 4 +Phagosome maturation 0.5821923815295095 1.3418316304799878 0.1796505938465928 1.0 0.3537819682201721 5 Q9BZG1 1 +Phospholipid transport 0.5498949206643621 1.3412160388784824 0.1798503204242669 1.0 0.3540225517745947 13 Q4KMQ2,Q9Y5P4,Q14108,Q8WTV0,P08183 5 +Positive regulation of endothelial cell proliferation 0.6011682930335769 1.3405351958339444 0.1800714097378692 1.0 0.3542841425474961 8 P09601 1 +Blood vessel endothelial cell migration 0.4857140710840417 1.3393676853994574 0.1804510039001057 1.0 0.3549220420373359 20 P42785,O94813,P09601,Q8WTV0 4 +Protein localization to plasma membrane 0.3720909832649477 1.3345620306254675 0.1820197320442338 1.0 0.3574590938736331 68 Q9BZG1,Q13641,O95429,P41440,P31751,Q4J6C6,Q6IQ22,Q9Y4G8,P23634,P84095 10 +Response to dsrna 0.5198386946300961 1.3333095515202635 0.1824302404892912 1.0 0.357936284522913 16 P41440,Q5KU26 2 +Collagen metabolic process 0.5842279728279045 1.3329578492796172 0.1825456366206954 1.0 0.3579572555026344 10 Q32P28,Q92791,P08670,Q9UBG0 4 +Carnitine metabolic process 0.580377517906153 1.3329365830939022 0.1825526159497834 1.0 0.3579572555026344 5 P23786 1 +Positive regulation of neuron migration 0.5471982875569098 1.328907275628739 0.1838785631795882 1.0 0.3601165872230861 4 Q9Y4G8 1 +Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.579477284813293 1.328523196192135 0.1840053257687532 1.0 0.3602547764745597 5 P11940,Q9Y5S9 2 +Mammary gland duct morphogenesis 0.5097087378640824 1.3259644025227513 0.1848514887642922 1.0 0.3615801168688169 3 Q15648,Q99623 2 +Protein targeting to membrane 0.439610612983161 1.324291837076806 0.1854061404871441 1.0 0.3624438427943256 33 Q5BJH7,P46379,P31751,O60725,P43307,P27105,Q9Y3D6 7 +Regulation of heart rate by chemical signal 0.4723390488515125 1.3186004315334303 0.1873027293724563 1.0 0.3652776005855669 2 P09493 1 +Establishment of protein localization 0.2904892476550234 1.31857385760345 0.1873116182721932 1.0 0.3652776005855669 498 P46379,Q96PC5,Q8NBM4,O60830,O60831,Q4J6C6,Q99595,O75396,P36405,P50402,P55786,Q969T9,P40616,Q15388,Q8N4H5,Q9UI26,P55196,Q9BXS5,Q8WWC4,Q7Z434,P60602,Q16836,O60749,O95831,P30040,Q9NVJ2,Q9BRK0,O95563,O43615,O94979,O15127,Q9Y584,Q9P0I2,P53367,P53350,Q8N183,P31751,Q92538,Q8N1F7,O60725,P37108,A6NIH7,P62072,P35579,Q16850,P06493,Q96RT1,O43731,Q9HD20,Q96FZ7,Q9UBU9,Q32P28,Q6NUQ1,P0CG08,O15118,O00429,O15027,P20338,Q8NC96,O14653,Q5BJH7,Q96CS3,P24390,Q12955,O00410,Q13555,Q6IQ22,O60826,O75298,O43865,P09132,Q8N6T3,Q99496,Q15717,Q7Z3B4,P50570,Q6WKZ4,Q96EE3,Q9Y2V7,P05771,Q96RL7,Q9BZG1,P50416,Q14C86,Q9Y282,Q10713,Q9P0J0,O95429,Q9NS69,Q14108,P50897,P04114,P02786,Q13432,P43307,P35241,O95817,O43464,Q9UFC0,Q06481,P27105,O43823,O15126,P83436,Q03518,Q9H814,P60520,P51572,P20645,O15400,P57740,Q9NPA0,Q9H267,Q96P70,Q5JRX3,Q9Y3D6,O00459,P49321,Q9Y2D4,Q96AX1,O43681,Q13190,Q92974,O75381,Q9UP83,Q9P2W9,Q99567,P35580,O95071,O15504,Q9NRW7,Q9Y2T2,O60499,O96028 134 +Positive regulation of immune response 0.3701022665587894 1.314896066172883 0.1885448350206813 1.0 0.3669011513304697 65 P07948,P46379,P23396,Q08722,P12956,Q7Z434,P04439,O15400,Q06481,O96028,Q9NQT5,Q9UJZ1,Q9NUQ9,P02786,P05771 15 +Positive regulation of fatty acid metabolic process 0.5437573056319358 1.3111809213526548 0.1897966464937053 1.0 0.3691130169977703 4 P31751 1 +Lipid homeostasis 0.4462054708022442 1.3106508952003189 0.1899757358262488 1.0 0.3693492467838201 30 Q9Y5P4,Q96CP7,O15118,Q9HCL2,Q8WTV0,Q5BJF2 6 +Negative regulation of viral transcription 0.506796116504859 1.310006798825314 0.1901935356021609 1.0 0.36956895630722 3 Q4G0J3,P14373 2 +B cell activation involved in immune response 0.5310023259701202 1.307154033093155 0.1911604033990763 1.0 0.3705286319286602 14 Q9NQT5,P02786,Q9UQ84 3 +Immunoglobulin production involved in immunoglobulin mediated immune response 0.5310023259701202 1.307154033093155 0.1911604033990763 1.0 0.3705286319286602 14 Q9NQT5,P02786,Q9UQ84 3 +Somatic diversification of immunoglobulins involved in immune response 0.5310023259701202 1.307154033093155 0.1911604033990763 1.0 0.3705286319286602 14 Q9NQT5,P02786,Q9UQ84 3 +3 utr mediated mrna stabilization 0.5936584478796388 1.3040138107956984 0.1922288735298138 1.0 0.3721495256194826 8 P16989,P07910,P98175 3 +Detoxification of nitrogen compound 0.5055425354905183 1.303135927316868 0.1925283598745508 1.0 0.3726167834528596 3 Q5VT66 1 +Cartilage development 0.5666651293241141 1.301242507482182 0.1931754595119126 1.0 0.3737129962369862 11 Q96HY6,O75844,Q92896 3 +Response to muscle stretch 0.5051779935275129 1.3011375751549434 0.1932113681013061 1.0 0.3737129962369862 3 P35222,P06744 2 +Regulation of catabolic process 0.2836930454699032 1.3001490557444484 0.1935498871745864 1.0 0.3742548346271792 287 Q13614,P46379,Q9P0J0,Q9UL46,Q7L8L6,P21796,O15118,Q96B26,Q14108,Q9NQT5,Q08J23,Q9Y5K8,Q8NHS3,Q9Y5A7,P67809,Q9Y487,Q96PU5,P35241,P23634,O95831,O95817,Q92530,Q96HY6,Q96J02,P16989,Q92879,Q14011,P08670,O43464,P09601,Q969T7,Q92804,Q8WTV0,Q8TBX8,Q8N163,P50416,Q9H814,P31751,P60520,P51572,Q05086,Q16850,Q9H2J4,Q93050,O43847 45 +Regulation of dendritic spine development 0.5294361887509207 1.2982201355250296 0.1942117008774795 1.0 0.3750819531860933 14 Q05086,Q9UQB8,Q9NUL3 3 +Regulation of gene expression by genomic imprinting 0.5411505771887426 1.2977449167203008 0.1943750034371076 1.0 0.3752842686842952 4 Q8NB78 1 +Response to abiotic stimulus 0.3194461283926805 1.296334468238481 0.1948602784305235 1.0 0.3756701835722372 201 P12956,P30519,P55786,P02786,Q96K76,P49748,Q9BUP0,Q15118,Q9Y487,Q13432,P23634,O95831,O95817,Q9UNS1,P16989,Q14011,P22830,P00846,P50570,O43464,P09601,Q06481,Q13794,Q9BRK5,P08183,Q9NXR7,P07948,Q8N163,P31751 29 +Positive regulation of nucleobase containing compound transport 0.5408078602680908 1.2959779905533086 0.1949830677220261 1.0 0.3756701835722372 4 P52298,Q07666 2 +Positive regulation of rna export from nucleus 0.5408078602680908 1.2959779905533086 0.1949830677220261 1.0 0.3756701835722372 4 P52298,Q07666 2 +Regulation of phosphatidylinositol 3 kinase activity 0.5728020741622645 1.2957760866915764 0.1950526389889804 1.0 0.3756873244950013 5 P07948 1 +Extracellular matrix assembly 0.572602236755699 1.2947951736029484 0.1953908973900693 1.0 0.3759826850870244 5 Q7Z460,O60568,Q96AY3 3 +Regulation of bone resorption 0.503975505518109 1.29454482963308 0.1954772949379379 1.0 0.3759826850870244 3 P02786 1 +Regulation of bone remodeling 0.503975505518109 1.29454482963308 0.1954772949379379 1.0 0.3759826850870244 3 P02786 1 +Erk1 and erk2 cascade 0.4380405582485685 1.2892710203211488 0.1973038821428583 1.0 0.378771453889105 32 P07948,Q13641,Q99956,Q15375,Q9Y4G8,Q96P70,P04899 7 +Organic anion transport 0.3744572658118461 1.287771453848823 0.1978255319769553 1.0 0.3791140183602317 55 Q8TDW0,P30825,Q15758,Q08722,P41440,O95563,Q9UHQ9,Q9Y5P4,Q9Y619,Q99808,Q9BQT8,Q9Y6M7,Q86VD7 13 +Chloride transmembrane transport 0.5971856571536773 1.2874822189752824 0.197926263247574 1.0 0.3791140183602317 7 Q9UHG3 1 +Regulation of phospholipid metabolic process 0.552123920090029 1.2863716645892729 0.1983133825113994 1.0 0.3794060940866148 12 Q13614,P17655,O75874,Q8WTV0,Q9UJZ1,Q96DA6 6 +Ras protein signal transduction 0.3655846888193866 1.2862817598077907 0.1983447459101788 1.0 0.3794060940866148 58 Q92766,P50570,P41440,Q6IQ22,Q15392,Q9Y4G8,P35241,Q96RT1,P84095,Q15047 10 +Defense response to bacterium 0.5196543035321687 1.285362164024609 0.1986657564056893 1.0 0.3797934681063132 15 P60602,Q5KU26 2 +Cell cycle g2 m phase transition 0.3991257550396947 1.284821693101667 0.198854599949535 1.0 0.3800411406310434 44 Q68E01,P50570,P53350,Q13564,P06493,Q9Y619,Q9ULX6,P38398,O43823,Q96JB5,P08183,P14635,Q96K76,Q9NXR7 14 +Rna stabilization 0.4473976481623586 1.2835386979081256 0.1993034109761242 1.0 0.3807853545028186 28 P16989,Q15717,Q14011,P67809,Q9H814,Q92804,P07910,P98175,O60506,Q08J23,P11940 11 +Positive regulation of neuron projection development 0.4563831106941867 1.2800799638156062 0.200517014485122 1.0 0.3827617816705278 23 Q32P28,Q9UQB8,Q9Y4G8,Q14108 4 +3 utr mediated mrna destabilization 0.6019882119720046 1.2793499008427516 0.2007738675789494 1.0 0.3831379848708144 6 Q9H2U1,Q9HCE1,Q92900 3 +Positive regulation of nf kappab transcription factor activity 0.4575362013190251 1.2778691999865734 0.2012955496381283 1.0 0.3837850495141495 22 Q96HY6,P23396,P41440,P02786,P05771,Q92974 6 +Negative regulation of ubiquitin dependent protein catabolic process 0.45604517258404 1.2777079046136623 0.2013524370539914 1.0 0.3837850495141495 23 Q96HY6,P46379 2 +Regulation of reactive oxygen species metabolic process 0.4417515918676923 1.276882870806463 0.2016436023913528 1.0 0.3842257703117038 30 P42785,Q9BTZ2,P60602,P51790 4 +Modification of synaptic structure 0.5879099660785337 1.2760284173152414 0.2019454738321102 1.0 0.3845723372738642 8 O95793,Q9UQB8 2 +Negative regulation of glycolytic process 0.5005566998020704 1.275793605535912 0.2020284885941976 1.0 0.384616160347136 3 Q9NQ88 1 +Embryonic appendage morphogenesis 0.572674976831472 1.2743488110294587 0.2025398250445249 1.0 0.3852101684726725 10 P42892 1 +Connective tissue development 0.456388032655699 1.2698893998768248 0.2041240295296329 1.0 0.3873449769738684 22 Q9BZK7,O15173,Q92896 3 +Synaptic signaling 0.3660340222867411 1.269712661172174 0.2041870011224182 1.0 0.3873449769738684 73 Q13614,Q13641,P41440,Q9UBB6,Q9NR77,P51790,Q4J6C6,Q13432,Q9Y4G8,Q9UQB8,P50897,P05771 12 +Positive regulation of lamellipodium assembly 0.548908282114897 1.2691021315866415 0.2044046401473429 1.0 0.387643119332683 12 Q16625 1 +Positive regulation of canonical wnt signaling pathway 0.4916862344290751 1.2640183277895725 0.2062234487096175 1.0 0.3908531754882781 18 Q8N163,O95071,Q9NWU2,Q9BZK7,Q96K76 5 +Neurotransmitter receptor transport endosome to postsynaptic membrane 0.4983818770226585 1.263860134140818 0.2062802328669024 1.0 0.3908531754882781 3 P61006,Q14160 2 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.4981658890599342 1.262674785441499 0.2067060792235495 1.0 0.3912606926633139 3 Q96HY6 1 +Response to ether 0.4980582524271887 1.2620840592013092 0.2069185406498417 1.0 0.3914840158103558 3 P11802,Q14103 2 +Endothelial cell proliferation 0.5152577346036221 1.2597068038389383 0.2077751500455749 1.0 0.3927569188416794 15 P09601 1 +Neuron apoptotic process 0.3976767112735923 1.25612242409306 0.209071587154495 1.0 0.3948582420920192 43 Q99720,O95831,P09601 3 +Negative regulation of intracellular estrogen receptor signaling pathway 0.5329808118342997 1.25559986312436 0.2092610810312662 1.0 0.3949833714400521 4 P38398,Q92600 2 +Oxaloacetate transport 0.4613393723714019 1.254225447019323 0.209760073037323 1.0 0.3955757776314329 2 Q02978 1 +Succinate transmembrane transport 0.4613393723714019 1.254225447019323 0.209760073037323 1.0 0.3955757776314329 2 Q02978 1 +Negative regulation of cellular protein catabolic process 0.435222889919117 1.2465718050924877 0.2125545452723696 1.0 0.399552678943076 31 Q96HY6,Q8N163,P46379,P60520,Q96JB5,Q9H2J4,Q92530 7 +Dna deamination 0.4948705051395639 1.2445855151556242 0.213284147478892 1.0 0.4005717507587746 3 Q9NQT5 1 +Regulation of synapse assembly 0.5738473596210094 1.2422012155074629 0.2141623313199143 1.0 0.4017502322975274 9 Q15375,Q9Y4F1,Q13641 3 +Golgi to plasma membrane protein transport 0.5191808733801077 1.2396653978932637 0.2150991806326525 1.0 0.4033896278102115 14 Q4J6C6 1 +Muscle organ development 0.4194648345051552 1.23829933373553 0.2156050907623314 1.0 0.4039838151963007 36 P16989,P41440,Q9BYT8,Q9NQ29,Q9Y5Q8,P80723 6 +Inner cell mass cell differentiation 0.4584276933031534 1.2371665371766891 0.2160252618379441 1.0 0.4046528136707252 2 Q9NVX2 1 +Response to iron ion 0.5865670674658119 1.2367616051983732 0.2161756000784875 1.0 0.4048161251834956 7 P09601 1 +Endoplasmic reticulum organization 0.3900480385599088 1.2347262676600756 0.2169323963951432 1.0 0.4056407995603466 46 Q00765,P46379,Q9H5V9,Q9BRK0,Q9Y5P4,O94979,O00429,Q12981,Q9P2W9,O43681,Q9NPA0,Q9P0I2,Q8NHH9,Q9C0E8 14 +Lens development in camera type eye 0.5601138302617303 1.2334436425040385 0.2174102908989788 1.0 0.4062702889423826 5 P08670 1 +Sperm motility 0.5858260245917956 1.233219855132463 0.2174937495585358 1.0 0.4062702889423826 7 Q96RL7,P23634 2 +Vacuolar acidification 0.5713767131574574 1.229908897532085 0.2187312219801689 1.0 0.4077924638831509 9 Q93050,Q9Y487,O75503,P50897 4 +Carbohydrate homeostasis 0.3961856056733999 1.2284011003646116 0.2192964350219743 1.0 0.4084098031954827 42 O00459,P42785,O95563,Q06481,Q99808,Q96RR1,Q12824,P49366 8 +Cellular response to nutrient 0.5847419265843848 1.2280381107916858 0.2194326618104902 1.0 0.4084098031954827 7 Q13573,Q96C86,P09601,Q8TB36 4 +Establishment of endothelial barrier 0.5408219543756128 1.225644086973379 0.2203326395798139 1.0 0.4097279430538461 12 P35241,Q9Y4G8,P55196 3 +Positive regulation of transcription elongation from rna polymerase ii promoter 0.5704764363387329 1.2254290639744123 0.2204136018862525 1.0 0.4097596253163802 9 O14776 1 +Bone marrow development 0.4558395341313537 1.221998353854948 0.2217082494962525 1.0 0.4113972295265344 2 Q9Y3A5 1 +T cell proliferation involved in immune response 0.4558395341313515 1.221998353854935 0.2217082494962574 1.0 0.4113972295265344 2 P62753 1 +Negative regulation of neuroblast proliferation 0.4558395341313483 1.2219983538549162 0.2217082494962645 1.0 0.4113972295265344 2 P35221 1 +Peripheral nervous system development 0.5697681742152524 1.221904486826518 0.2217437485201523 1.0 0.4113972295265344 9 Q9NR77 1 +Negative regulation of immune effector process 0.5767070858478385 1.2214333465357152 0.2219219878305742 1.0 0.4116087795121473 8 P46108,P09601,Q08722 3 +Regulation of adenylate cyclase activity 0.5262272003452482 1.220728753495797 0.2221887372143223 1.0 0.4118161460482881 4 P04899 1 +Regulation of cyclase activity 0.5262272003452482 1.220728753495797 0.2221887372143223 1.0 0.4118161460482881 4 P04899 1 +Protein hexamerization 0.58942510581251 1.2204593916077489 0.2222907746220088 1.0 0.4118161460482881 6 Q8TDW0,Q96RR1 2 +Receptor internalization 0.4760344654771251 1.2184338167122553 0.2230591608891212 1.0 0.4128280305624 19 Q13614,P41440,P50570 3 +Imp salvage 0.4551924943383996 1.2182057193977411 0.2231458067698404 1.0 0.4128280305624 2 P07741 1 +Negative regulation of organelle assembly 0.575954753315614 1.2177650177864474 0.2233132815042047 1.0 0.4128751469402804 8 O75396,P50570,Q96KQ7 3 +Negative regulation of immune system process 0.4027408436599321 1.2166192238008988 0.2237491251014456 1.0 0.4134424594696645 40 P07948,Q96J02,O94813,Q08722,Q14166,P09601,P46108,Q9HCL2,P28070,P04439 10 +Hormone metabolic process 0.433743866601383 1.2160951421191697 0.2239486808837729 1.0 0.4136919436498515 30 O75844,O75787,Q9HB40,Q53GQ0,Q9BTZ2,O95470,P42892 7 +Dendrite development 0.3912583158048267 1.2128098229074982 0.2252025389669578 1.0 0.41576851232091 44 Q9BRT6,Q9Y4F1,Q13641,P46108,Q9NUL3,Q05086,Q96PU5,Q9Y4G8,Q9UQB8,Q86X55 10 +Regulation of electron transfer activity 0.5241178374878495 1.2098332527338669 0.2263428836555205 1.0 0.4171529281862814 4 Q9BSH4,Q04656,Q99623 3 +Intracellular transport 0.2850520158144135 1.2087241670368087 0.2267688338523139 1.0 0.4176977658026817 517 P46379,Q96PC5,Q8NBM4,O60830,P61221,Q4J6C6,Q99595,P23786,O75396,O43772,P55786,P36405,P50402,Q92734,P40616,Q15388,Q8N4H5,Q9UI26,Q9BXS5,Q8WWC4,Q7Z434,P60602,O75964,O60749,O95831,P30040,Q9NVJ2,Q9BRK0,Q9H5V9,P00846,O43615,O94979,Q9Y584,Q03001,Q13794,P53367,P31751,Q92538,Q8N1F7,O60725,P37108,P62072,P06493,O75431,Q96RT1,O43731,Q13614,Q96FZ7,Q8WU17,Q9UBU9,Q6NUQ1,Q14203,O15118,O15027,Q08J23,Q86V81,O14653,Q5BJH7,Q96CS3,Q6P6C2,P24390,Q12955,O00410,O43865,Q6IQ22,O60826,O75298,O75494,Q9Y5P4,Q9P260,O75503,Q96RL7,P50416,Q9ULX6,Q9Y282,P52298,Q10713,Q8NHH9,Q00765,Q9P0J0,O95429,Q9NS69,P11717,Q14108,P07437,P43307,P35241,O95817,Q9Y3Y2,O43464,Q06481,P27105,P83436,Q03518,Q9H814,P51572,P20645,O15400,P57740,Q9H267,Q96P70,P07196,Q9BUP3,Q86U42,Q5JRX3,Q9UJZ1,Q9Y3D6,O00459,Q9Y2D4,Q96AX1,P45880,O43681,Q13190,Q8WXH0,Q92974,Q6IAA8,O00148,O75381,O94901,Q9P2W9,Q99567,Q96D71,O95071,O75844,O15504,Q9NRW7,Q9NUL3,Q9Y2T2,O60499 129 +Positive regulation of wound healing 0.5738922839487962 1.2077076224004668 0.2271597450377371 1.0 0.4181558712768822 8 Q16625,Q92766 2 +Leukocyte cell cell adhesion 0.418666570217111 1.2058213202341488 0.2278863930068344 1.0 0.4191540255878934 35 P07948,Q96J02,P30825,P23396,Q08722,O43290,Q9HCL2,Q9NUQ9,P02786,P04439,P49366 11 +Acetyl coa biosynthetic process from pyruvate 0.5726855204126229 1.2018224286800732 0.2294323337266122 1.0 0.4215136885031769 8 O95563 1 +Insulin receptor signaling pathway 0.4464831427771725 1.200993107105225 0.2297538751355401 1.0 0.4218502094321057 22 O00459,P31751,Q9HCD5,Q9H1E3,P05771,Q9UQB8,Q8TBX8,P04899 8 +Establishment of protein localization to plasma membrane 0.4557253031315575 1.2008408620776123 0.2298129378060707 1.0 0.4218502094321057 21 Q15904,Q9BZG1,P55196,Q12955,Q4J6C6,O15027,Q8N2H4 7 +Regulation of endothelial cell development 0.4864498112093788 1.198334624462151 0.2307867722706142 1.0 0.4229332747690076 3 P35611 1 +Retinal metabolic process 0.5218760796363002 1.1982523210436185 0.2308188021010067 1.0 0.4229332747690076 4 Q9BTZ2 1 +Positive regulation of neurotransmitter secretion 0.4516337754772076 1.1973428688901706 0.2311729418166128 1.0 0.4229332747690076 2 Q00535 1 +Calcium ion regulated exocytosis of neurotransmitter 0.4516337754771946 1.197342868890095 0.2311729418166423 1.0 0.4229332747690076 2 P16615 1 +Negative regulation of viral entry into host cell 0.450986735684247 1.193549125207545 0.2326543848708211 1.0 0.424997038193777 2 O60493 1 +Negative regulation of viral life cycle 0.450986735684247 1.193549125207545 0.2326543848708211 1.0 0.424997038193777 2 O60493 1 +Regulation of response to osmotic stress 0.5829377716915577 1.1900268173409785 0.234035851899947 1.0 0.4263057148845298 6 Q9BUP0,P16989,P08183 3 +Neuron death 0.3583353371629625 1.189429603778467 0.2342706572378683 1.0 0.4266121911632772 63 P17655,O43464,Q96A26,Q99720,P31751,P09601,Q15392,Q9UMX5,Q15375,P50897,O95831,P07196 12 +Positive regulation of epithelial cell apoptotic process 0.4845042966227161 1.1876450906467595 0.2349732652131799 1.0 0.427527286408312 3 Q4KMQ2 1 +Regulation of rna export from nucleus 0.5443457834613021 1.1846838952615062 0.236142452320256 1.0 0.4288185490139474 11 Q08J23,Q9ULX6 2 +Positive regulation of mitophagy in response to mitochondrial depolarization 0.4838187702265423 1.183878305630192 0.2364612390327725 1.0 0.4291383188561924 3 O95140,Q16543 2 +Respiratory gaseous exchange by respiratory system 0.5440779634439386 1.1832840300958725 0.2366965998048118 1.0 0.4294438734075414 11 O60476 1 +Response to x ray 0.532316098827753 1.1798999964048618 0.2380399913109392 1.0 0.4312708717645903 12 P12956 1 +Positive regulation of immune system process 0.3453891035726275 1.1783065408409827 0.2386744211328131 1.0 0.4319319704859774 98 P46379,P12956,Q9HCL2,Q9NQT5,Q9UJZ1,P02786,P49366,P23396,Q96J02,Q4KMQ2,Q08722,P09601,Q06481,P05771,P07948,P30825,O43290,O15400,O96028 19 +Endothelin receptor signaling pathway 0.448075056615994 1.1764760297910462 0.2394047055355215 1.0 0.4322738576231131 2 P46109 1 +Epithelial cell proliferation involved in lung morphogenesis 0.4480750566159863 1.1764760297910006 0.2394047055355397 1.0 0.4322738576231131 2 Q13247 1 +Regulation of epithelial cell proliferation involved in lung morphogenesis 0.4480750566159863 1.1764760297910006 0.2394047055355397 1.0 0.4322738576231131 2 Q13247 1 +Positive regulation of epithelial cell proliferation involved in lung morphogenesis 0.4480750566159863 1.1764760297910006 0.2394047055355397 1.0 0.4322738576231131 2 Q13247 1 +Cardiac conduction system development 0.4480750566159863 1.1764760297910006 0.2394047055355397 1.0 0.4322738576231131 2 Q14126 1 +Regulation of nervous system process 0.5674552421374928 1.176311865728536 0.2394702758845046 1.0 0.4322738576231131 8 Q9UQB8 1 +Carbohydrate derivative transport 0.4428179549285652 1.175481316012558 0.2398022078590962 1.0 0.4327511690250019 22 Q8TDW0,Q08722,P41440,Q8WTV0,Q86VD7 5 +Positive regulation of membrane potential 0.5796469035035933 1.1745861873080083 0.2401603120618514 1.0 0.4332378487124709 6 Q9UJZ1,P31751 2 +Inflammatory response 0.3563774898415661 1.1744693808276447 0.2402070693173357 1.0 0.4332378487124709 61 P07948,Q96J02,P42785,Q92879,Q08722,P09601,P28070,Q06481,P02786 9 +Meiosis i cell cycle process 0.4517265626767286 1.1737659921553596 0.240488769155384 1.0 0.4334738061215129 21 Q92791,P46379,Q9BXW9,O94901,Q96KQ7 5 +Positive regulation of extrinsic apoptotic signaling pathway 0.5528826617657223 1.1737569585439591 0.2404923885358454 1.0 0.4334738061215129 10 Q9NQX7,Q13794 2 +Positive regulation of lipid kinase activity 0.5171117570504546 1.1736362153003326 0.2405407688571328 1.0 0.4334738061215129 4 Q99570,P07948 2 +Regulation of cholesterol metabolic process 0.5599932987948542 1.1732469054936676 0.2406968071659916 1.0 0.4336330899196195 9 P49748 1 +Negative regulation of response to external stimulus 0.4049033977332308 1.1730642568265406 0.2407700386981111 1.0 0.4336431435950806 38 P07948,Q96J02,O94813,Q14166,P46108,P04439,Q9UMX5,P28070,P80303,Q96G23 10 +Positive regulation of type i interferon mediated signaling pathway 0.4811581916432305 1.1692585237801774 0.2422994883969687 1.0 0.4359078643347093 3 Q7Z434 1 +Reactive nitrogen species metabolic process 0.4995291975852739 1.1678271578241508 0.2428764911134824 1.0 0.4368233187534855 15 P23634,Q5VT66,P50570,Q08722 4 +Negative regulation of protein catabolic process 0.3970120204391319 1.1667335334762865 0.2433179961871534 1.0 0.4373719449129707 40 Q96HY6,Q8N163,P46379,P60520,Q16850,Q92530 6 +Endoplasmic reticulum to golgi vesicle mediated transport 0.356688874030811 1.1643443176240595 0.2442845033743375 1.0 0.4386592400873749 66 Q5BJH7,Q8WU17,O43731,Q96PC5,Q9H5V9,P24390,Q8NHH9,Q6NUQ1,P51572,Q92538,O94979,O75396,Q9Y282,Q9P2W9,Q13190,Q92734,O14653 17 +Response to copper ion 0.5774518487488103 1.1642866217807222 0.244307876304513 1.0 0.4386592400873749 6 P35670,P02786,P06493 3 +Cilium or flagellum dependent cell motility 0.5577784137270715 1.1622196518139942 0.2451462540840323 1.0 0.4397949870357255 9 Q96RL7,P23634,Q00796,P04114,Q9NVR5 5 +Protein localization to cilium 0.5577391156240599 1.1620239973571012 0.2452257173783742 1.0 0.4398144511458811 9 Q9Y5K8,Q10713 2 +Positive regulation of chromatin organization 0.5504993659907047 1.1616372218486035 0.2453828559299271 1.0 0.4399731766463868 10 Q15047 1 +Mitochondrial membrane organization 0.3783202777132456 1.1605785264490018 0.2458133422686805 1.0 0.4404986088739844 48 Q9P0J0,Q9NS69,Q13505,P60602,Q5XKP0,Q9Y584,P62072,Q13794 8 +Organic hydroxy compound biosynthetic process 0.3646787071665723 1.159771659359736 0.2461417856576051 1.0 0.4408485943307739 54 Q9BZF3,P48449,P61457,P14324,Q15392,Q9Y4G8,Q16850,P04114,Q15800 9 +Positive regulation of dna methylation dependent heterochromatin assembly 0.569989378322862 1.157494978753747 0.2470701896028146 1.0 0.442009465630489 7 Q15047 1 +Small gtpase mediated signal transduction 0.3555194746215393 1.156621944845068 0.24742685244388 1.0 0.44240059251472 77 O94813,Q92766,P50570,P41440,P09601,Q6IQ22,Q15392,P80303,Q9Y4G8,P35241,Q96RT1,P84095,Q15047 13 +Positive regulation of kinase activity 0.3641813958630608 1.1546747269247266 0.2482236527477002 1.0 0.4434472566818135 54 P07948,P23396,P12956,Q15375,Q99627,Q13432,Q9NQ88,Q9Y4R8,Q9Y4G8,P23634,Q96M27,P14635,P30040 13 +Protein deglycosylation 0.562836703124981 1.1537830353948342 0.2485891309931975 1.0 0.4436656372198013 8 O60476 1 +Negative regulation of immune response 0.4740964942286172 1.1537818858506863 0.2485896024004681 1.0 0.4436656372198013 18 P07948,Q14166,P46108,P09601,P28070,P04439 6 +Lipid droplet formation 0.4441928178582968 1.1537105140688262 0.2486188719022661 1.0 0.4436656372198013 2 Q9Y679 1 +Mitotic dna replication 0.5487756746642114 1.1528717505373882 0.2489630286653206 1.0 0.4441205735914307 10 O75844,Q9BY42,Q14566,Q9BRX5,P25205,P33991 6 +Nadh dehydrogenase complex assembly 0.4229795803438548 1.152415319540695 0.2491504487654758 1.0 0.4441205735914307 31 Q9P0J0,Q9H061,Q96CU9,Q9Y375,P03886,O96000 6 +Organic hydroxy compound metabolic process 0.3291607098563038 1.1504464593476356 0.2499600341336632 1.0 0.4454362171586428 113 Q13614,Q9BZF3,P49748,P48735,P04114,P48449,P61457,P38435,O15118,Q9BTZ2,Q16850,Q9UNW1,Q9Y4G8,Q8WTV0,Q10713,P30837 16 +Pteridine containing compound metabolic process 0.4814730279531954 1.149973014898316 0.2501549858690608 1.0 0.4454362171586428 17 P41440,P61457 2 +Phagocytosis 0.3913264129306459 1.149840620767471 0.2502095212191175 1.0 0.4454362171586428 41 Q9BZG1,P50570,Q08722,P51790,Q06481,Q8WTV0,P84095,Q5KU26 8 +Positive regulation of calcium mediated signaling 0.4432222581688833 1.1480192304977372 0.2509606251840521 1.0 0.4462295721025727 2 P26599 1 +Positive regulation of calcineurin mediated signaling 0.4432222581688833 1.1480192304977372 0.2509606251840521 1.0 0.4462295721025727 2 P26599 1 +Transmembrane receptor protein serine threonine kinase signaling pathway 0.3945924869669497 1.14565547468522 0.2519377338237429 1.0 0.4474704554752542 40 P08670,P50570,Q9UIQ6,Q6PIU2,Q92896 5 +Regulation of leukocyte mediated immunity 0.4306949045209071 1.145078942933634 0.2521764573395928 1.0 0.4475224505943493 27 P07948,Q7Z434,P09601,P46108,O15400,O96028,Q9NQT5,Q9NUQ9,P02786,P04439 10 +Cellular response to reactive oxygen species 0.4306482862161558 1.1447367705549 0.2523182146182898 1.0 0.4476500846120227 27 Q99720,P60602 2 +Membrane raft organization 0.5604050121383638 1.1419217808179838 0.2534865341845025 1.0 0.4491013499509843 8 P41440,O15118 2 +Nuclear transcribed mrna catabolic process exonucleolytic 0.5137639108120816 1.1411944422174192 0.2537890166506342 1.0 0.4492647325961241 13 Q96C86,Q5RKV6,Q969T7,Q96B26,Q9NQT5 5 +Rrna 3 end processing 0.5658816825890818 1.137850450693497 0.2551829343117453 1.0 0.4514829171786606 7 Q96B26,P63220,Q9NQT5 3 +Positive regulation of dna demethylation 0.440957618893566 1.134740223583275 0.2564841786207217 1.0 0.4532443399840621 2 Q93009 1 +Regulation of supramolecular fiber organization 0.3515454920059719 1.1342214909097872 0.2567016514485776 1.0 0.4534190095853905 83 O94813,Q13045,O95429,Q08722,P23396,Q16625,P29372,Q96F07,P28289,P36405,P62993,Q9UEY8,O60925,P35241,Q9UQB8,P53367,Q92974,P35611 18 +Humoral immune response 0.5006302472450195 1.1336155099264489 0.2569558642390039 1.0 0.4537429999371943 14 Q9UQ84 1 +Extracellular transport 0.4406340989970944 1.1328433270949514 0.2572800528720949 1.0 0.4538682920222612 2 Q9NVR5 1 +Positive regulation of histone h4 acetylation 0.4744882306886973 1.1326078327562692 0.2573789778636497 1.0 0.4538682920222612 3 Q12824 1 +Regulation of actin filament organization 0.3568548343849546 1.1326033792759422 0.2573808489080997 1.0 0.4538682920222612 56 O94813,Q13045,O95429,Q96F07,Q9UEY8,P35241,Q9UQB8,P53367 8 +Positive regulation of dendritic spine development 0.5445303980468591 1.1312844931658423 0.257935368940843 1.0 0.4544710596236403 10 Q9UQB8,Q9NUL3 2 +Regulation of fatty acid oxidation 0.5391967572471066 1.130565589381262 0.2582379776128476 1.0 0.4547542407962508 5 P49748,P50416,P31751 3 +Glial cell proliferation 0.508192710978463 1.1275525359198717 0.259508941490493 1.0 0.4565497037148074 4 Q96G23 1 +Receptor metabolic process 0.4197379676828031 1.1274732304459758 0.2595424524706331 1.0 0.4565497037148074 31 Q13614,P50570,P41440,P42892,P02786 5 +Intracellular protein transport 0.2760605600587819 1.1256050068838894 0.2603327478591526 1.0 0.4578142424628719 307 P46379,Q9P0J0,Q8NBM4,O95429,O60830,Q9NS69,Q5JRX3,Q99595,P50402,P55786,Q14108,Q9Y3D6,P40616,O00459,Q8N4H5,Q5BJH7,Q15388,Q9UI26,Q9BXS5,Q9Y2D4,Q8WWC4,Q7Z434,P60602,Q96AX1,P43307,O43681,O60749,Q13190,O95831,O95817,Q92974,P30040,Q9BRK0,O43464,O75381,O43615,Q9Y584,Q06481,P27105,Q9P2W9,Q99567,P53367,Q96RL7,P83436,O95071,O15504,P31751,P51572,P20645,Q9NRW7,O60725,Q9Y282,O15400,P57740,Q9Y2T2,P62072,Q10713,O60499,Q9H267,Q96P70,Q96RT1 61 +Cell projection organization 0.3042681657182846 1.122824598094786 0.2615119961980967 1.0 0.4595098398108005 222 Q13614,O94813,O95429,Q16181,Q32P28,Q9Y4G8,Q14108,P42892,P84095,Q9BUP0,Q13641,P41440,Q16625,Q9NR77,Q13555,Q96PU5,P35241,Q9UQB8,P08670,P50570,Q96F07,Q06481,Q9NQX7,P07948,Q9BZG1,Q92766,Q9UBB6,P46108,Q05086,A6NIH7,Q66K14,Q86X55,Q96G23,P07196 34 +Atp transport 0.5623011676594973 1.1207292684283945 0.2624031197899614 1.0 0.4606967948106417 7 Q86VD7 1 +Positive regulation of mrna metabolic process 0.3529675583661002 1.120183495043894 0.2626355758554952 1.0 0.4608540188684884 57 Q92879,Q96C86,Q9HCE1,Q14011,P67809,Q969T7,Q96E39,Q96B26,P98179,P52298,P62995,Q9NQT5,O60506,P11940,P38159 15 +Regulation of dendrite morphogenesis 0.498010692000131 1.118639271127057 0.2632940626678184 1.0 0.4618814837714056 14 Q96PU5,Q9UQB8 2 +Regulation of mrna catabolic process 0.3528522744186452 1.1184698324232705 0.2633663838987703 1.0 0.4618819482328639 68 Q96C86,Q7L8L6,Q96B26,P98175,Q9NQT5,Q99729,Q9HCE1,Q6P6C2,P67809,P07910,P16989,Q92879,Q14011,Q15717,P08670,Q13310,Q969T7,Q92804,Q06787,P51114,Q9Y5S9,O60506,P35637,Q13868,P11940 25 +Negative regulation of microtubule polymerization 0.5059889932016728 1.1161684971181358 0.2643500164906502 1.0 0.4633534606795373 4 Q9BTW9,Q15691,Q02790 3 +Negative regulation of cell cycle g2 m phase transition 0.4342407173418994 1.115771075486329 0.2645201378615822 1.0 0.4635248998613291 22 Q68E01,P53350,Q13564,Q9Y619,P38398,Q96JB5,P06493,Q96K76,Q9NXR7 9 +Microglial cell activation 0.4373989000323581 1.1138764820844764 0.2653321799611932 1.0 0.4645982988229696 2 P01130 1 +Regulation of microglial cell activation 0.4373989000323581 1.1138764820844764 0.2653321799611932 1.0 0.4645982988229696 2 P01130 1 +Protein polyubiquitination 0.3788211130758683 1.113665730477488 0.2654226162698463 1.0 0.4645982988229696 45 Q96J02,Q9UIQ6,P52888,Q05086,P55786,Q96PU5,Q16763 7 +Negative regulation of hormone metabolic process 0.4370753801358754 1.1119800560489208 0.2661467255328436 1.0 0.4655564940063779 2 O60678 1 +Locomotory behavior 0.4222040755346675 1.111806826800071 0.2662212159873873 1.0 0.4655564940063779 29 Q96RL7,O75844,P54802,O43464,P51790,P28289,O15118,Q05086,P50897 9 +Adult behavior 0.4511529539037023 1.111715374816756 0.2662605471181563 1.0 0.4655564940063779 20 O75844,O43464,P51790,P28289,O15118,P50897 6 +Positive regulation of neural precursor cell proliferation 0.5657815857137871 1.1095348875581752 0.2671995027677056 1.0 0.4669435149239349 6 P07948,P04899 2 +Cell activation involved in immune response 0.4147526561447945 1.1079593172955366 0.267879386063595 1.0 0.4678765298821919 32 P07948,Q92538,P09601,Q9UQ84,O96028,Q9NQT5,P02786 7 +Export across plasma membrane 0.5467712659523267 1.1074258422310064 0.2681098581038497 1.0 0.4681262946676048 9 P08183,Q4KMQ2,P33527 3 +Production of molecular mediator of immune response 0.4145248560035818 1.106184608952991 0.2686466231677995 1.0 0.46883333909763 32 P09601,Q9UQ84,Q9Y3Z3,O96028,Q9NQT5,P02786,P04439 7 +Regulation of endothelial cell migration 0.4285153996218844 1.104204239384994 0.2695045510844334 1.0 0.4700746047486307 25 P42785,O94813,P09601,Q8WTV0 4 +Amino acid transport 0.4498655963429746 1.103228893806972 0.2699277766858312 1.0 0.4706847248520615 20 Q8TDW0,P30825,Q15758,Q9Y619,Q96H78 5 +Golgi disassembly 0.5033119909619403 1.1023420264722008 0.2703130049967139 1.0 0.4712282736004722 4 Q13190,Q92538 2 +Negative regulation of response to stimulus 0.3042957995083993 1.1012526323829002 0.270786720491565 1.0 0.4717864210058549 218 Q13614,O94813,Q9P0J0,Q8NBM4,Q9HBM6,Q99956,P50402,P80303,Q96K76,Q92896,O00459,Q13641,P23396,P67809,Q9UMX5,P28070,P45880,P23634,Q9NPR9,Q8N0X7,P04899,Q92974,Q96HY6,Q96J02,P16989,P50570,Q08722,O43464,P09601,Q06481,Q9NWT1,Q96JB5,Q8TBX8,P05771,P07948,Q8N163,O95071,Q14166,P46108,Q9HCD5,P04439,Q10713,Q96P70,Q96RT1,Q96G23,P78318 46 +Regulation of vacuole organization 0.5283488865283181 1.1010752108973405 0.270863924843886 1.0 0.4717864210058549 11 O75396,Q8TBX8,Q14108 3 +Inflammatory response to antigenic stimulus 0.5380256829565779 1.098216670933778 0.2721098883276092 1.0 0.472945874235351 10 P28070 1 +Response to mineralocorticoid 0.5631987667150609 1.0974220790308458 0.2724569260957474 1.0 0.4731310883710329 6 O95831 1 +Positive regulation of protein phosphorylation 0.3489001940251907 1.0969324125121025 0.2726709385649204 1.0 0.4731310883710329 82 O95429,P12956,Q9Y4G8,P02786,Q8IZP0,P23396,P41440,Q7Z434,Q99627,Q13432,P23634,Q96M27,P30040,Q92974,Q96HY6,P54652,Q06787,P51114,Q15375,P14635,P07948,P53350,P31751,Q9Y4R8 24 +Lysosomal protein catabolic process 0.5446339416033092 1.096790163143769 0.2727331312840821 1.0 0.4731310883710329 9 Q8NHS3,O14773 2 +Protein catabolic process in the vacuole 0.5446339416033092 1.096790163143769 0.2727331312840821 1.0 0.4731310883710329 9 Q8NHS3,O14773 2 +Membrane invagination 0.5056762984027617 1.0963809431287896 0.2729121001140533 1.0 0.4731854373089212 13 Q06481,P84095,P51790,Q4KMQ2 4 +Negative regulation of protein containing complex disassembly 0.4288803064159925 1.0962079244145355 0.2729877925071857 1.0 0.4731886830641051 24 Q13045,P29372,P28289,Q9UEY8,P35241,Q92974 6 +Signal release 0.3694401168348738 1.0943944840312485 0.2737820020982999 1.0 0.4743088198513791 49 O95563,P50416,Q13555,Q4J6C6,Q6WKZ4,P50897,P05771 7 +Regulation of oxidoreductase activity 0.4721529769794799 1.0929498837453218 0.2744158044673161 1.0 0.4747652649488519 17 P23634,Q8WTV0 2 +Establishment of endothelial intestinal barrier 0.5562167239012878 1.0916438629710568 0.274989668589753 1.0 0.4753731865319086 7 Q9Y4G8 1 +Cellular component maintenance 0.5356775323757307 1.0862837786853952 0.2773534614383 1.0 0.4785875949024275 10 Q13614,Q9BRK5,Q9C0E8 3 +Regulation of nervous system development 0.3549722657263103 1.085735152296978 0.2775961837522005 1.0 0.4788274905352943 55 Q13614,P07948,O94813,Q13641,Q9NUL3,Q15375,Q06481,Q9Y4G8,Q9UQB8,Q8N0X7,Q96G23,P07196 12 +Steroid metabolic process 0.3500120173091302 1.0853876677216825 0.2777499920699466 1.0 0.4788535366240877 69 P49748,Q9BZF3,Q9UHQ9,Q53GQ0,P48449,Q9H3P7,P14324,O15118,Q15392,Q9BTZ2,O95470,Q16850,Q8WTV0,P04114,P38435,Q15800,Q9BX68 17 +Multi multicellular organism process 0.4295204374425979 1.0829211206026097 0.2788434363035437 1.0 0.4804802222327191 22 P41440 1 +Response to nitrogen compound 0.3027161360740978 1.0825065698397935 0.2790274977128095 1.0 0.4806681699379493 220 P46379,O94813,Q8NBM4,P49721,O15118,Q9Y4G8,Q96KQ7,Q15388,O00459,P17655,P41440,Q7Z434,Q16836,Q6IQ22,Q8IXB1,Q9H1E3,P62993,Q5TDH0,Q9UQB8,P23634,O95831,P04899,Q5KU26,Q92974,Q9UNS1,Q6IAA8,P08670,P50570,Q92575,P63151,Q06481,Q13794,Q8TBX8,P05771,Q5VT66,P33527,P07948,P28161,P50416,P31751,P51572,P46108,Q9HCD5,P09960,Q05086,Q86X55,Q96RT1,P07196 48 +Response to light stimulus 0.3680621625104152 1.081068999268776 0.2796664221022291 1.0 0.4814411300195249 49 Q8N163,Q14011,P22830,P50570,P31751,Q9BRK5,Q96K76 7 +Cellular response to topologically incorrect protein 0.3905774745199746 1.080286565761437 0.2800145901854687 1.0 0.4818506102251958 39 Q7Z2K6,P46379 2 +Golgi to plasma membrane transport 0.4251366243577311 1.0799516374621858 0.280163716916479 1.0 0.4819778382808992 25 Q9BZG1,P50570,Q9Y2D4,Q12955,Q4J6C6,O60826,P36405,O15027 8 +Cellular protein catabolic process 0.3016516406866362 1.0792680521855924 0.2804682504948981 1.0 0.4822428877876332 223 P46379,P49721,Q9UL46,Q9NWU2,Q9BZK7,P50897,O00231,Q96K76,Q16763,Q8NHS3,P17655,Q9Y5A7,Q99436,Q96TA2,Q6IQ22,Q8IXB1,P28070,Q96PU5,P35241,O14773,P28074,Q92530,Q96HY6,Q96J02,Q9UHG3,Q92575,O43464,P20618,Q13794,Q9UJX3,Q96RL7,Q8N163,P60520,P51572,Q05086,Q8NBM8,Q9H2J4 37 +Neurotransmitter receptor transport to plasma membrane 0.4985432178698492 1.07772097403902 0.2811582955001248 1.0 0.4829112202989818 4 Q13277,P61006,Q14160 3 +Protein localization to postsynapse 0.4985432178698492 1.07772097403902 0.2811582955001248 1.0 0.4829112202989818 4 Q13277,P61006,Q14160 3 +Negative regulation of actin filament depolymerization 0.4836494621749403 1.0750488495464956 0.2823528583488346 1.0 0.4847032196079351 15 Q9UEY8,P35241,Q13045,P28289 4 +Respiratory chain complex iv assembly 0.5465798537266005 1.0745157886620185 0.2825915722526906 1.0 0.4849831266773083 8 Q7KZN9 1 +Protein localization to organelle 0.273754210589537 1.0727171952579293 0.2833980228808268 1.0 0.4857169322636631 307 P46379,Q9P0J0,Q8NBM4,O95429,O60830,Q9NS69,Q5JRX3,P29372,Q99595,P36405,P55786,Q8NEY8,Q14108,Q96DY7,Q9Y5K8,P02786,Q9Y3D6,P40616,O00459,Q8N4H5,Q15388,Q9UI26,P67809,P24390,Q8WWC4,Q7Z434,P60602,P35241,O43681,O14773,O95831,O95817,Q96HY6,O43464,O75381,O94901,Q9UFC0,O43615,Q9Y584,Q06481,Q99567,Q96JB5,Q9P0I2,Q13561,Q96RL7,P83436,O95071,Q5JTV8,P53350,P60520,P51572,Q96FF9,P20645,Q92538,Q8N1F7,P37108,Q9Y2T2,P57740,P62072,Q10713,Q13895,Q9NPA0,Q96P70,O43731 64 +Carbohydrate transmembrane transport 0.5122114561207043 1.0717851520048498 0.2838165436789774 1.0 0.4860443614700095 12 P31751,P05771,Q16625 3 +Cerebral cortex cell migration 0.5325061213649451 1.070172277841786 0.2845417701792563 1.0 0.486766145409403 10 O94813,Q8WXH0 2 +Regulation of intracellular estrogen receptor signaling pathway 0.5008517886754204 1.0696636993203474 0.2847707115663214 1.0 0.4870278178068623 13 Q96HY6,Q969T9,Q9NUQ7,Q86X55 4 +Exonucleolytic catabolism of deadenylated mrna 0.5389506211931329 1.0685204710967766 0.2852858012488533 1.0 0.4877786038957454 9 Q96B26,Q96C86,Q969T7,Q9NQT5 4 +Homeostatic process 0.2721320531341959 1.0672815028167424 0.2858447381995832 1.0 0.488466818444811 298 O15254,Q9HD20,P42785,Q96JM7,P30519,P0CG08,O15118,P23786,Q9HCL2,Q9HC07,P50897,P04114,Q9UJZ1,P02786,Q5BJF2,Q9Y3D6,Q16763,P49366,P49748,O00459,O95793,Q16625,Q96CP7,Q96AX1,Q9Y487,Q96PU5,P23634,O14773,Q9NX40,Q9Y6M7,P04899,O95817,Q6IAA8,Q4KMQ2,O95563,Q9Y5P4,Q9UIQ6,P09601,O75503,Q14157,Q06481,Q96RR1,Q99808,Q13794,Q8WTV0,Q96JB5,Q12824,P05771,P28161,P07948,O43819,Q9UBB6,P51572,P51790,Q9P0S9,Q05086,Q96H78,Q93050,O43847 59 +B cell mediated immunity 0.4752695449109897 1.067121604605372 0.2859169271146538 1.0 0.488466818444811 16 Q9NQT5,P02786,Q9UQ84 3 +Regulation of hepatic stellate cell activation 0.4293109026205116 1.0664876171582127 0.2862032733711492 1.0 0.4886955200610193 2 Q15418 1 +Negative regulation of protein secretion 0.5447790753569359 1.065742655683944 0.286539989562413 1.0 0.4891401686005506 8 Q16836,Q16850,P30040,Q6WKZ4 4 +Primary amino compound metabolic process 0.4618122977346331 1.0630013667332625 0.2877813315340152 1.0 0.4908670396841504 3 P05091,Q04656 2 +Protein oxidation 0.4286638628275638 1.062699003406502 0.2879184729672799 1.0 0.4909502746543892 2 Q96JJ7 1 +Positive regulation of wnt signaling pathway 0.4254346374936804 1.0625560820579754 0.2879833124337758 1.0 0.4909502746543892 23 O95071,Q8N163,Q9NWU2,Q9BZK7,Q96K76 5 +Negative regulation of macroautophagy 0.5204254691201687 1.059696953162739 0.2892824893770873 1.0 0.4923793831405018 11 O75396,P09601,O15118,Q96KQ7 4 +Positive regulation of mapk cascade 0.3945605096633827 1.0587405414465694 0.2897179589646499 1.0 0.4927280756071653 37 Q13641,Q6IAA8,P23396,P29372,Q9UMX5,Q9Y4G8,P04899,P18615 8 +Response to cocaine 0.5431988880576901 1.0580460604189552 0.2900344437927087 1.0 0.4928891855379733 8 Q05086 1 +Positive regulation of actin filament polymerization 0.5096458007104303 1.0580018180241917 0.2900546135598343 1.0 0.4928891855379733 12 Q9UQB8 1 +Long chain fatty acid transport 0.4806213067406008 1.057372487741905 0.2903416226253981 1.0 0.4930039208023316 15 P23786,P31751,O43772 3 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.421657544843 1.054989676310204 0.2914300463224037 1.0 0.4941025056942635 25 P83436,P24390,Q92538,O75396,Q12981,Q9Y282,Q9P2W9,O43731 8 +Cellular modified amino acid metabolic process 0.3466156548310386 1.052509883626247 0.2925656783378438 1.0 0.4957298435489238 57 Q9UHG3,P41440,O60725,Q8NCC3,P23786 5 +Regulation of mrna splicing via spliceosome 0.3465344795882182 1.050992531541624 0.2932620199773992 1.0 0.4966078453704433 66 P61978,Q86U06,P62995,P98175,Q13247,Q9H0G5,Q9NR56,Q15637,Q13573,O75525,O75494,P98179,Q16629,P08621,Q8IY67,P38159,Q92879,Q14011,Q96E39,Q06787,O00422,P51114,Q9Y5S9,O95319,Q07666,Q96PU8 26 +Lipid metabolic process 0.271977017610057 1.05087441645187 0.2933162718521838 1.0 0.4966078453704433 288 Q13614,Q9BZF3,O15254,Q9BWD1,Q9H6V9,Q86YN1,Q8NHP8,P14324,O15118,P23786,Q9BZK7,Q9HCL2,Q9BTZ2,Q9NPH0,P50897,P04114,Q9UJZ1,Q8N4Q0,P49748,O00459,Q15102,P17655,Q13011,Q15118,Q9UHQ9,Q53GQ0,Q8NCC3,Q8NBX0,Q15392,O95470,O43681,O14773,A1L0T0,Q9BX68,Q9Y2B2,O43464,Q9Y5P4,P48449,Q06481,Q86UY6,Q8WTV0,Q8TBX8,P38435,O60762,P07948,Q8IY17,Q9HB40,P50416,P31751,P46108,Q9H3P7,Q9H6K4,P09960,Q10713,Q6PIU2,Q16850,P07099,Q15800,Q96G23 59 +Telomere maintenance 0.3450194821667253 1.0503853073333524 0.293540998037255 1.0 0.4968570893632966 61 P12956,Q9UQ84 2 +Dna strand elongation involved in dna replication 0.5071267565533564 1.044474480895216 0.2962659199070461 1.0 0.5002804390421932 12 P25205,P49005,P33991 3 +Iron ion transport 0.5272918647194939 1.0436985849304787 0.2966248647552976 1.0 0.5007546439508711 10 O15173,P50570 2 +Regulation of biomineralization 0.5515940367355124 1.0430423110564844 0.2969286970526479 1.0 0.5010036715207878 6 O75844,Q4KMQ2 2 +Meiotic cell cycle 0.3599953877140634 1.0423840050255604 0.297233679187229 1.0 0.5013862851552994 51 Q92791,P46379,Q9BXW9,P53350,O94901,Q9BSJ2,Q9UQ84,Q9UQE7,P35579,Q96KQ7,Q08J23,Q9NTJ3 12 +Columnar cuboidal epithelial cell differentiation 0.5398362612851736 1.041674249850418 0.297562731381956 1.0 0.5018092891760952 8 Q9P287,Q9NQ88,P07437,P04818 4 +Regulation of histone phosphorylation 0.5511042141233452 1.0407490741095933 0.2979920208737439 1.0 0.5023019436769954 6 Q9NY27,O43823,Q9ULX6 3 +Adherens junction assembly 0.4572815533980635 1.0381533839267163 0.2991986512826745 1.0 0.5040376753539931 3 P35222,Q9BTW9 2 +Lamellipodium organization 0.4214756906781808 1.0347533040790655 0.3007841354545795 1.0 0.506043650462954 23 Q16625,O94813,P50570 3 +Regulation of endocytic recycling 0.4238110643804544 1.0343004447113353 0.3009957290330023 1.0 0.5062667601945802 2 Q9H4M9 1 +L alpha amino acid transmembrane transport 0.5154189888830351 1.033576914434556 0.3013339963444388 1.0 0.5064816107471295 11 P30825,Q9Y619 2 +Export from cell 0.3091296737674361 1.033520228337378 0.3013605091091345 1.0 0.5064816107471295 130 Q32P28,Q4J6C6,P50897,Q13555,Q6IQ22,P04899,O95563,P09601,Q6WKZ4,Q9BRK5,P53367,P05771,P08183,O15126,P07948,Q15758,O43760,P50416,Q16850 19 +Inorganic anion transmembrane transport 0.5049409633911423 1.0327418410307727 0.301724727260606 1.0 0.5068628790044283 12 Q9UHG3 1 +Regulation of cellular response to transforming growth factor beta stimulus 0.4941707592761906 1.03269743509732 0.3017455142403897 1.0 0.5068628790044283 13 Q92896 1 +Negative regulation of helicase activity 0.4559870550161865 1.03105834154331 0.3025134617035403 1.0 0.5078185682519423 3 P49736,P33993 2 +Negative regulation of organic acid transport 0.4894799283818157 1.0309758955429629 0.3025521235809933 1.0 0.5078185682519423 4 P31751 1 +Positive regulation of transmembrane transport 0.4112727975822087 1.029759055154666 0.3031231257547899 1.0 0.5082446340800951 29 Q16625,P08183,P31751 3 +Cerebral cortex neuron differentiation 0.4553398058252481 1.0275116336954335 0.3041796102312455 1.0 0.5089022558342311 3 P43034,Q96ST3 2 +Lipophagy 0.4885076076400032 1.025965963694024 0.3049076277597895 1.0 0.5099029204122753 4 O15269,Q9Y679,O15270 3 +Negative regulation of mitotic cell cycle 0.363938251359627 1.023046372765994 0.3062859207004484 1.0 0.5116738993197484 48 Q68E01,Q9BXW9,P53350,Q13564,Q9Y619,P38398,Q96JB5,P06493,Q96DY7,P14635,O60566,Q96K76,Q9NXR7 13 +Somatic diversification of immunoglobulins 0.453102031934909 1.0222556904239546 0.3066598988526385 1.0 0.5120317665135226 18 Q9NQT5,P02786,O96028,Q9UQ84 4 +Positive regulation of lamellipodium organization 0.4810493501362833 1.0217736526607666 0.3068880421916304 1.0 0.5121795807112159 14 Q16625,P50570 2 +Leukocyte degranulation 0.5295334407718318 1.0217310048183184 0.3069082323731327 1.0 0.5121795807112159 9 P09601 1 +Female sex differentiation 0.5227894055165405 1.0208588953177378 0.307321296128042 1.0 0.5125211737225622 10 Q05086,P57740,O94813 3 +Regulation of tube size 0.535544265667949 1.0207924309529526 0.3073527912308158 1.0 0.5125211737225622 8 P42892 1 +Negative regulation of mrna splicing via spliceosome 0.4738566106720475 1.0179201616958802 0.3087158992908807 1.0 0.5142590734029484 15 P61978,O75494,O00422,Q16629,P98175,Q13247,P38159 7 +Positive regulation of protein polyubiquitination 0.4865652314664822 1.0159612103877371 0.3096478584895963 1.0 0.5152759015883469 4 P61088,O00571,O75150 3 +Negative regulation of inflammatory response 0.5118892942046106 1.015177287949708 0.3100213249799433 1.0 0.5156296557139171 11 P28070 1 +Pigment biosynthetic process 0.4184924761908892 1.0138186838567502 0.3106692782743891 1.0 0.5162373520396482 23 Q7KZN9,Q9Y4G8,P22830 3 +Ribonucleoside diphosphate catabolic process 0.4202523455192661 1.013496197331376 0.3108232115599052 1.0 0.5162373520396482 2 Q9BW91 1 +Nucleoside diphosphate catabolic process 0.4202523455192661 1.013496197331376 0.3108232115599052 1.0 0.5162373520396482 2 Q9BW91 1 +Crd mediated mrna stabilization 0.5339961060290219 1.013264845549398 0.3109336742728548 1.0 0.5162373520396482 8 P67809,O60506 2 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.5339961060290219 1.013264845549398 0.3109336742728548 1.0 0.5162373520396482 8 P67809,O60506 2 +Response to hydrogen peroxide 0.4143425914103112 1.0132297050467591 0.3109504549493107 1.0 0.5162373520396482 26 Q99720,O95831,P09601 3 +Regulation of nucleobase containing compound transport 0.5011555371530328 1.0124358594946197 0.3113296999549981 1.0 0.5164035899354645 12 Q08J23,Q9ULX6 2 +Mrna cis splicing via spliceosome 0.4515245187232236 1.01239116817116 0.3113510594733033 1.0 0.5164035899354645 18 O75400,P52298 2 +Membrane disassembly 0.5392769459773148 1.0107867193074715 0.3121185208416488 1.0 0.5172388103916673 7 Q9ULX6,P05771,P53350 3 +Regulation of fatty acid transport 0.514329987676131 1.0084284997931947 0.3132487967622006 1.0 0.5187095807919675 5 P31751 1 +Cellular response to dsrna 0.5267667673673081 1.008001540790954 0.3134537225451184 1.0 0.5189148660935456 9 P41440 1 +Cilium movement 0.5196842557865233 1.0051205243352987 0.3148388182851724 1.0 0.5204014505435677 10 Q96RL7,Q00796,P23634,P04114,Q9NVR5 5 +Wound healing 0.3394839012270049 1.0047947640676036 0.314995685620427 1.0 0.5205265132320024 58 P07948,P42785,Q92766,Q16625,P09601,Q8WTV0,Q96AY3,P38435 8 +Cellular response to acid chemical 0.488539780509298 1.0015811243944408 0.3165459411478721 1.0 0.5228187278427882 13 Q99729,P17655,Q6IAA8,Q9UQB8,Q9P2J5 5 +Dna replication initiation 0.4139478381161723 0.9997342348861242 0.3174391397078842 1.0 0.5236193735274158 25 Q9UFC0,Q9Y619,Q9BRX5,Q96S55,P25205,P33991 6 +Neutrophil degranulation 0.4173406664510046 0.996490738452262 0.3190117648245549 1.0 0.5245015530444305 2 P51809 1 +Neutrophil activation involved in immune response 0.4173406664510046 0.996490738452262 0.3190117648245549 1.0 0.5245015530444305 2 P51809 1 +Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.5179615978774144 0.9963945317786168 0.3190584888461134 1.0 0.5245015530444305 10 O60313,P18031,Q13794,O95881,P30040 5 +Immune effector process 0.3414015337012371 0.9963628166798518 0.3190738926777392 1.0 0.5245015530444305 65 P07948,Q9NVJ2,Q08722,P07437,Q7Z434,P09601,Q92538,Q9UQ84,P46108,O15400,Q06481,O96028,Q9NQT5,Q9NUQ9,P02786,P04439 16 +Regulation of cell shape 0.4085326654841722 0.9952500919373424 0.3196146444861432 1.0 0.5246044223078712 28 P35580,O75400,Q16181,P46108,P35241,Q9UQB8,P84095 7 +Vesicle docking 0.4699439330527556 0.9951297826338664 0.3196731471972769 1.0 0.5246044223078712 15 Q13190,O15400,Q6IQ22 3 +Threonine catabolic process 0.4163701067615613 0.9908258680492292 0.3217706156793665 1.0 0.5275063034538975 2 P52758 1 +Regulation of cytoplasmic translation 0.4753782479492238 0.9894582423099528 0.3224389907369747 1.0 0.527959167299408 14 P67809,O60506,P16989 3 +Exocrine system development 0.4482200647249243 0.9885389686164816 0.3228887594233889 1.0 0.5283590951835948 3 O00330,P61011 2 +Cell fate determination 0.4482200647249225 0.9885389686164716 0.3228887594233938 1.0 0.5283590951835948 3 P35222,Q07820 2 +Carboxylic acid transport 0.388173051617205 0.9813486039851396 0.3264208620410249 1.0 0.5328408744393531 36 P30825,P41440,O95563,Q9Y619,Q9BQT8 5 +Positive regulation of amyloid precursor protein catabolic process 0.4796872748923564 0.9805765079497762 0.3268016237785729 1.0 0.5332989838138117 4 P07948 1 +Forebrain cell migration 0.5051129766654554 0.9798989989346728 0.3271359771657431 1.0 0.5335485832621435 11 O94813,Q8WXH0 2 +Regulation of protein targeting to membrane 0.5210356563026645 0.9795920635405592 0.3272875240852961 1.0 0.5335485832621435 9 Q9Y3D6,P31751,Q12955,P27105 4 +Positive regulation of protein targeting to membrane 0.5210356563026645 0.9795920635405592 0.3272875240852961 1.0 0.5335485832621435 9 Q9Y3D6,P31751,Q12955,P27105 4 +L amino acid transport 0.4947250855644326 0.9779865536222924 0.3280809745238626 1.0 0.5343481009905917 12 P30825,Q9Y619 2 +Lipid digestion 0.4462783171521086 0.977925023033595 0.3281114080341605 1.0 0.5343481009905917 3 P01130,Q9UHB6 2 +Intestinal lipid absorption 0.4462783171521086 0.977925023033595 0.3281114080341605 1.0 0.5343481009905917 3 P01130,Q9UHB6 2 +Intra golgi vesicle mediated transport 0.4532779629832842 0.9777000190271484 0.328222712367634 1.0 0.5343935957014311 17 P83436,P60520,Q9UP83,Q9Y2V7,Q8TBA6,O14653 6 +Membrane protein ectodomain proteolysis 0.5320901612967442 0.9765692924953748 0.3287824276503843 1.0 0.5351689591769843 7 Q9NZ08,O43847,P38159 3 +Positive regulation of transporter activity 0.4381106573787739 0.9749768539356034 0.3295717414049153 1.0 0.5361814371587581 19 P50570,Q13586,Q12955,P54652,Q03164,P08183,P28161 7 +Sulfur amino acid catabolic process 0.445307443365701 0.9726207770624508 0.3307418124424282 1.0 0.5375393047048591 3 Q13867,P25325 2 +Regulation of monooxygenase activity 0.5129848976591547 0.9712092098253992 0.3314441085686135 1.0 0.5381433349025416 10 Q8WTV0 1 +Hormone mediated signaling pathway 0.3745509295725305 0.9711576693666608 0.3314697696914503 1.0 0.5381433349025416 40 Q96HY6,P42785,O15173,Q05086,Q06481,Q9NUQ7 6 +Transition metal ion homeostasis 0.4069583868458382 0.971078838616247 0.3315090206737299 1.0 0.5381433349025416 27 Q9Y487,P09601,P30519,O43819 4 +Post golgi vesicle mediated transport 0.3656649938568866 0.9656608900086732 0.3342138957596403 1.0 0.5418085664692197 43 Q96RL7,Q9BZG1,P50570,Q9Y2D4,Q12955,O14976,Q92538,Q4J6C6,O60826,O15127,P36405,O15027,P42566,Q8N2H4,O75695,O15126 16 +Cell recognition 0.4436591781912639 0.9632756746321284 0.3354091973398279 1.0 0.543334080098129 18 P45880,Q5KU26,Q8WTV0 3 +Regulation of ras protein signal transduction 0.4088212450696193 0.9630588698349896 0.3355179809244504 1.0 0.5433729807290872 25 P50570,P41440,P46108,P35241,Q96RT1 5 +Positive regulation of release of cytochrome c from mitochondria 0.5290177042931804 0.9619625190307144 0.336068431801259 1.0 0.5441269633357086 7 Q96A26,Q13794 2 +T cell mediated cytotoxicity 0.5338940539051412 0.9603374230197256 0.3368854212517447 1.0 0.5449744128997132 6 O15400,P04439 2 +Regulation of antigen receptor mediated signaling pathway 0.5286562352536242 0.9602450101207864 0.3369319186149084 1.0 0.5449744128997132 7 P07948,P05771 2 +Tetrapyrrole biosynthetic process 0.4909323227154088 0.9576998889836754 0.3382141127687825 1.0 0.546293003946149 12 P22830,Q7KZN9 2 +Cellular response to radiation 0.3647660631611168 0.9575199381012252 0.3383048877955668 1.0 0.546293003946149 43 P31751,P12956,P50570,Q96K76 4 +Formation of translation preinitiation complex 0.5332814718137227 0.9574824009587334 0.3383238251294571 1.0 0.546293003946149 6 P55010 1 +Antigen processing and presentation of peptide antigen 0.4908842581264683 0.9574429733026316 0.3383437169526071 1.0 0.546293003946149 12 P50570,Q03518,Q9UIQ6,Q9NZ08,P10321 5 +Leukocyte proliferation 0.3905460370823824 0.9570454938691524 0.3385442930230544 1.0 0.5463416209158558 34 P07948,Q96J02,P30825,P23396,P17812,Q9HCL2,P02786,P49366 8 +Protein k6 linked ubiquitination 0.441936907265818 0.954221475707736 0.339971546126961 1.0 0.5475374662130954 3 Q16763 1 +Negative regulation of exocytosis 0.5325466413651441 0.9540584036746934 0.3400540800303171 1.0 0.5475374662130954 6 P09601 1 +Positive regulation of catabolic process 0.3041454992097918 0.9535673685861384 0.3403026799172517 1.0 0.5477296499362946 130 P46379,Q9P0J0,P21796,Q96B26,Q9NQT5,Q9Y5A7,P67809,Q96PU5,P35241,Q13190,O95817,Q96HY6,Q96J02,Q92879,P09601,Q969T7,Q96JB5,Q8TBX8,P50416,P31751,P51572,O95816,O60506,P11940,O43847 25 +Regulation of cell projection assembly 0.3691197805085647 0.9534851112851446 0.3403443363020688 1.0 0.5477296499362946 41 O94813,P50570,Q16181,Q16625,Q66K14,P84095 6 +Neuron migration 0.4189816655153651 0.952388455979066 0.3409000118526419 1.0 0.5484862138492558 21 Q9H9T3,Q9BSJ2,P46108,Q9Y4G8,Q92974 5 +Mammary gland epithelium development 0.5214126050946959 0.952196108010209 0.3409975344795137 1.0 0.5485054444199958 8 P31751 1 +Positive regulation of protein polymerization 0.4026401683641644 0.9516717685076062 0.3412634713402964 1.0 0.548742097862858 28 P23396,O95429,Q16625,P36405,Q9UQB8 5 +Response to osmotic stress 0.4182582994704115 0.9475185793528242 0.3433745934036145 1.0 0.5512224251733456 21 Q9BUP0,Q8TDW0,P16989,P08183 4 +Regulation of cell cycle g1 s phase transition 0.3982104956421234 0.9463316520460572 0.3439794541168774 1.0 0.5519307859834454 30 Q96HY6,Q9UL46,P35241,P23634,Q96DY7 5 +Negative regulation of dna binding transcription factor activity 0.4050663403422307 0.9461470917988006 0.344073567487527 1.0 0.5519307859834454 26 Q96J02,O75381,P09601,O60826,P42771,Q96JB5,Q93009,Q96RT1,Q99496 9 +Cellular response to hormone stimulus 0.309372389794462 0.944419709996374 0.3449552133088611 1.0 0.5530672629589295 118 P42785,O94813,O15118,P04114,O15173,Q6IQ22,P35241,Q9UQB8,O95831,P04899,Q96HY6,Q06481,O43823,Q8TBX8,P05771,P07948,P31751,P46108,Q05086,Q9NUQ7 20 +Negative regulation of cell development 0.4403228980059609 0.9424834655648956 0.3459451724757794 1.0 0.5543771388924364 18 Q8N0X7,Q96G23,Q06481,Q9Y4G8 4 +Neuron projection extension 0.3975552346479292 0.9413763730885948 0.3465120170361151 1.0 0.5547307765238506 30 O94813,Q96PU5,P50570 3 +Nuclear ncrna surveillance 0.5295279246626106 0.9400017612200956 0.3472166572732016 1.0 0.555027125466639 6 Q96B26,Q9NQT5 2 +Regulation of dna ligation 0.4392246880362183 0.9394343797473012 0.3475077685209604 1.0 0.5550771981608165 3 P18887 1 +Positive regulation of cytoplasmic transport 0.4999761025362885 0.938235140207475 0.3481235832815978 1.0 0.5552306964008565 5 Q13614 1 +Positive regulation of early endosome to late endosome transport 0.4999761025362885 0.938235140207475 0.3481235832815978 1.0 0.5552306964008565 5 Q13614 1 +Negative regulation of transporter activity 0.5120123445994839 0.9349660724241836 0.3498057843699231 1.0 0.5574233217565612 9 Q12955,Q96PU5,P28161 3 +Mrna transcription 0.5119964697781912 0.934887690426532 0.3498461815018168 1.0 0.5574233217565612 9 Q15648,Q12800,O00203,P52298 4 +Pyramidal neuron development 0.4381877022653746 0.9337854170868668 0.3504145933504876 1.0 0.5581902443778891 3 O14949,Q04656 2 +Protein localization to cell periphery 0.3366956785116282 0.9333376512091192 0.3506456610129591 1.0 0.5583999182415444 76 Q9BZG1,Q13641,O95429,P41440,P31751,Q4J6C6,Q6IQ22,Q9Y4G8,P23634,P84095 10 +Mitotic dna integrity checkpoint signaling 0.4069767130955642 0.93319276836023 0.3507204478690262 1.0 0.5583999182415444 23 Q9BXW9,P53350,Q13564,Q9Y619,P38398,Q96JB5,P06493,Q9NXR7 8 +Mitotic chromosome condensation 0.4863042081055512 0.9329831614365596 0.3508286624434946 1.0 0.5584335054042217 12 P53350,Q96FF9,Q9ULX6,O43823,Q9NTJ3 5 +Regulation of endothelial cell differentiation 0.4699404357334927 0.9305732993253448 0.3520743315378762 1.0 0.5597513965006615 4 Q9Y624,P35611 2 +Positive regulation of isotype switching to igg isotypes 0.406017470074422 0.9305367721662012 0.3520932341171088 1.0 0.5597513965006615 2 P43246 1 +Positive regulation of cellular component biogenesis 0.3200442834780113 0.9300819057952716 0.3523286784715469 1.0 0.5598479992569697 107 Q13641,P50570,O95429,P41440,Q16181,Q16625,Q08722,Q8NEY8,Q9UQB8,Q8TBX8,P02786,Q15047 12 +Positive regulation of blood circulation 0.43721682847897 0.928499078313328 0.3531487456780331 1.0 0.5602956285736589 3 P09493,P16615 2 +Negative regulation of steroid metabolic process 0.4372168284789698 0.9284990783133272 0.3531487456780335 1.0 0.5602956285736589 3 O75477,O94905 2 +Secondary alcohol metabolic process 0.3615434026831086 0.928357316016588 0.3532222519603987 1.0 0.5602956285736589 43 P49748,P48735,P48449,O15118,Q15392,Q16850,Q8WTV0,P04114,Q15800 9 +Telomere organization 0.3341038219551867 0.9266581256818026 0.3541040653765928 1.0 0.5615554327224046 62 P12956,Q9UQ84 2 +Amide transport 0.3725202267793346 0.925625226731038 0.3546407786884433 1.0 0.5621284350625425 39 P41440,Q9Y5P4,O95563,Q13555,P08183 5 +Positive regulation of intrinsic apoptotic signaling pathway 0.4513948182255516 0.9249815824851788 0.3549754877259914 1.0 0.5625070083534198 16 P51572,Q9Y3D6,Q13794 3 +Regulation of extrinsic apoptotic signaling pathway 0.4004188974713413 0.9233349271583168 0.3558326916367698 1.0 0.5635995931286618 27 O43464,P09601,Q13794,Q9NQX7,Q92974 5 +Deoxyribose phosphate metabolic process 0.4636542332562077 0.9228434177004452 0.3560888108513436 1.0 0.5637266677098327 14 Q9H773 1 +Negative regulation of erk1 and erk2 cascade 0.4734190223600266 0.9182946663973898 0.3584646188549061 1.0 0.5667879148643188 13 P07948,Q96S59,Q99956,Q96P70,P15311,Q13526 6 +Fatty acid transport 0.4361854862001258 0.9167401070046072 0.359278844057783 1.0 0.5677952145982221 18 P23786,P31751,O43772 3 +Regulation of canonical wnt signaling pathway 0.3854436385997484 0.9164481149983904 0.3594319090612687 1.0 0.567897100587314 34 Q8N163,O95071,O75787,Q13641,Q8NBM4,Q9NWU2,Q9BZK7,Q96K76 8 +Retinol metabolic process 0.5080255824185252 0.9152974783289952 0.3600354825731418 1.0 0.5687105577362837 9 Q9BTZ2,Q6UX07,Q6NUM9 3 +Respiratory system development 0.4031640145995996 0.914075361763926 0.360677247794269 1.0 0.5692314649259275 24 P80723,P46379,O60476 3 +Immunoglobulin production 0.4041765549135868 0.913646564800298 0.3609025902441543 1.0 0.5692314649259275 23 Q9NQT5,P02786,O96028,Q9UQ84 4 +Regulation of potassium ion transport 0.482372294170984 0.9120218702320952 0.3617572048327635 1.0 0.5700254874577222 12 Q96PU5,P50570 2 +Negative regulation of nf kappab transcription factor activity 0.4554725826216336 0.9111014339793008 0.3622419309690801 1.0 0.5706489991427386 15 Q96J02,Q99653,O60826,P42771,Q96JB5,Q93009,Q96RT1 7 +Regulation of transcription involved in g1 s transition of mitotic cell cycle 0.4336569579288084 0.9091375222432824 0.3632775384115971 1.0 0.5717183946030796 3 O75312,Q00535 2 +Phosphorylation of rna polymerase ii c terminal domain 0.4336569579288082 0.9091375222432808 0.363277538411598 1.0 0.5717183946030796 3 P50750,Q8WUA2 2 +Regulation of cellular response to osmotic stress 0.4938978875963996 0.9086240079820008 0.3635486293483407 1.0 0.5718642243246292 5 Q9BUP0,P16989 2 +Regulation of programmed necrotic cell death 0.5123416202051041 0.9083376142478984 0.3636998753273341 1.0 0.5719617764593259 8 P16989 1 +Antigen processing and presentation of exogenous peptide antigen 0.4924886849126309 0.9017704400448644 0.3671788254527959 1.0 0.5762305868907867 5 Q03518,Q9UIQ6,P50570 3 +Regulation of nitric oxide metabolic process 0.5049949058686838 0.9003686597295162 0.3679240934091314 1.0 0.576765331071786 9 P23634,P50570 2 +Snrna transport 0.4918234960448719 0.8985369620190978 0.3688993488892362 1.0 0.57772900717811 5 P52298 1 +Apoptotic cell clearance 0.5102096372309566 0.8980540825344374 0.3691567172402497 1.0 0.5778906708555037 8 Q8WTV0 1 +Polyol metabolic process 0.4182539029092652 0.8956007141541332 0.3704660541541709 1.0 0.5792251767009795 20 Q13614,Q9UNW1,P61457 3 +Regulation of establishment of protein localization to mitochondrion 0.4397185283564256 0.8953333878888554 0.3706088974086809 1.0 0.5792251767009795 17 P55786,O95817,O95429 3 +Anterograde neuronal dense core vesicle transport 0.3998705920414232 0.8948847615541632 0.3708486934759469 1.0 0.5792251767009795 2 P33176 1 +Dense core granule transport 0.3998705920414232 0.8948847615541632 0.3708486934759469 1.0 0.5792251767009795 2 P33176 1 +Leukocyte mediated cytotoxicity 0.4690399831202946 0.89427207964178 0.3711763347283259 1.0 0.579440332299255 13 Q9NVJ2,P07437,P46108,O15400,P04439 5 +Head development 0.3013180950111294 0.8941474331173677 0.3712430133928688 1.0 0.579440332299255 142 Q9H6E4,P46379,O94813,Q9Y4G8,P50897,Q15102,O95470,Q9UQB8,P23634,P80723,Q8WXH0,O95817,Q5KU26,P54802,O43464,O94901,O75503,Q15375,Q96JB5,Q9NQZ2,Q9BRK5,Q9BXW9,O75787,P46108,Q05086,O95456,Q9UKA9,P07196 28 +Terpenoid metabolic process 0.4254379893302471 0.8941201006219742 0.3712576356869017 1.0 0.579440332299255 19 Q9HB40,O43464,P48449,P14324,Q9BTZ2 5 +Iron ion homeostasis 0.4321140604905601 0.8914587217502261 0.3726831269244597 1.0 0.5809578899770882 18 Q9Y487,P09601,P30519 3 +Tor signaling 0.4519872834964492 0.8909439922412177 0.3729592178503753 1.0 0.5811056359798021 15 O75844,Q8NHS3,Q6IAA8,Q96EE3,Q9P2J5 5 +Metal ion homeostasis 0.3314421579529071 0.8893217131188366 0.3738302053996989 1.0 0.5823211705011107 83 Q9HD20,P30519,Q9HC07,Q9UJZ1,P02786,Q9Y3D6,Q8N511,Q13586,Q14344,Q8WWC4,Q12955,Q6P4Q7,Q9Y487,Q96PU5,P23634,P04899,Q96TC7,P09601,P05771,P28161,P07948,O43819,P35670,P51572 24 +Terpenoid biosynthetic process 0.4614567075162054 0.8872239781251654 0.3749583253346615 1.0 0.5835112564688469 4 P48449 1 +Organelle membrane fusion 0.3882991609473993 0.8862688683463851 0.3754726605974965 1.0 0.5839926634445745 31 Q9BZG1,P31751,O75396,Q12981,O15400,O60499,Q13190,O14653 8 +Response to muscle activity 0.4892367208171655 0.885972959632418 0.3756320984995289 1.0 0.5839926634445745 5 Q9UDX5 1 +Endosome to plasma membrane protein transport 0.4886658031088065 0.8832022780493207 0.377126991001008 1.0 0.5854773106424728 5 Q96QK1,Q15904,P61006,Q14160 4 +Glial cell development 0.4566105989055328 0.8829865321300991 0.3772435482078315 1.0 0.5854773106424728 14 P31751,P08670 2 +Mapk cascade 0.3311348026556971 0.8817177299299025 0.3779294706586558 1.0 0.5861427309271675 82 Q86U42,P29372,Q99956,Q9Y4G8,O00459,Q13641,P23396,P62993,Q9UMX5,P04899,Q96J02,Q6IAA8,Q15375,Q96JB5,P07948,O75787,Q96P70,P18615,P78318 19 +Regulation of exocytosis 0.3731883136238315 0.8812333912900373 0.3781915096709085 1.0 0.5864072513281383 37 P09601,Q6IQ22,Q4J6C6,P04899,P05771 5 +Regulation of ion transmembrane transport 0.3352168816814734 0.8808898334438001 0.3783774506606243 1.0 0.5865536780494806 55 P07948,O75844,Q4KMQ2,P50570,P21796,P0CG08,Q96PU5,P27105,P23634,P08183,P28161 11 +Cellular response to nitrogen compound 0.3000109449285139 0.8783016522338711 0.3797800394190243 1.0 0.5884433291457447 122 O94813,Q9Y4G8,Q96KQ7,O00459,P17655,P41440,Q7Z434,Q6IQ22,Q9H1E3,P62993,Q5TDH0,Q9UQB8,P23634,O95831,P04899,Q5KU26,Q92974,Q9UNS1,Q6IAA8,P08670,P50570,Q06481,Q8TBX8,P05771,P33527,P28161,P07948,P31751,P46108,Q9HCD5 30 +Regulation of neutrophil migration 0.505851028085857 0.877063692761741 0.3804520438350911 1.0 0.5891997103123784 8 O94813,P84095,Q00013 3 +Execution phase of apoptosis 0.4656160545435673 0.875527050191342 0.3812871985556887 1.0 0.5903504692613442 13 O43464,Q12981,O95831 3 +Smooth muscle cell proliferation 0.4222513373490428 0.8738698692112347 0.3821891251680966 1.0 0.5912435094325244 19 P12956 1 +Protein lipid complex subunit organization 0.5104095863437794 0.8738656866300762 0.3821914032065807 1.0 0.5912435094325244 7 Q8WTV0 1 +Regulation of dendrite development 0.4148818553740314 0.873610140788456 0.3823306017784924 1.0 0.5912435094325244 20 P46108,Q96PU5,Q9Y4G8,Q9UQB8 4 +Regulation of histone h2b ubiquitination 0.45872450631271 0.8733047154122859 0.3824970110405097 1.0 0.5912435094325244 4 Q5VTR2,P50750,O75150 3 +Amino acid transmembrane transport 0.4488451497535134 0.8728041363067647 0.3827698446905287 1.0 0.5915030627932231 15 Q8TDW0,P30825,Q15758,Q9Y619,O75746,O60831,Q96NB2 7 +Mitochondrion endoplasmic reticulum membrane tethering 0.426860841423954 0.8722799149135115 0.3830556920478529 1.0 0.5918021176251477 3 P16615,O43865 2 +Lipid modification 0.3365872347207197 0.872060471706235 0.3831753888247964 1.0 0.5918443957510712 54 Q13614,P49748,Q9BWD1,Q13011,P50416,P31751,P23786 7 +Histone exchange 0.4584455626442207 0.8718848785968433 0.3832711837694709 1.0 0.5918497441489541 4 Q6IPU0 1 +Vascular endothelial cell proliferation 0.3956648333872498 0.8705679547843647 0.3839900999306382 1.0 0.5926743415736555 2 P40763 1 +Positive regulation of vascular endothelial cell proliferation 0.3956648333872498 0.8705679547843647 0.3839900999306382 1.0 0.5926743415736555 2 P40763 1 +Membrane biogenesis 0.4141956587370791 0.8691407328981482 0.3847701596138797 1.0 0.5937353690719714 20 P41440 1 +Dendritic spine development 0.3983717900764045 0.867159660435744 0.3858545354669402 1.0 0.5951221300151798 22 Q9UQB8 1 +Organelle fusion 0.3503467044608413 0.8636827855162176 0.3877621727524458 1.0 0.5979205021272981 46 Q9BZG1,Q9NVJ2,Q13190,P31751,Q9NX63,O75396,Q12981,O15400,O60499,Q9UJZ1,P02786,Q9Y3D6,O14653 13 +Negative regulation of erad pathway 0.3940472339048813 0.8612338740452892 0.3891092470130655 1.0 0.5997091304048449 2 O43765 1 +Er overload response 0.4561346714146927 0.860131605141307 0.3897165010523127 1.0 0.6005006662849337 4 Q9UM00,O76024,Q96A33 3 +Negative regulation of establishment of protein localization 0.393022304068814 0.8594666617976875 0.3900831054044855 1.0 0.6009211020530527 26 Q99653,P30040,Q9Y385,Q8NBM4,O95429,Q8N183,Q16836,Q6WKZ4,Q16850,Q96DZ1,O95817 11 +Fatty acid beta oxidation 0.3646501057011421 0.8585514944018245 0.3905880089110565 1.0 0.6015543337625834 39 P49748,Q9BWD1,Q13011,P31751,P23786 5 +Positive regulation of peptidase activity 0.3644803099720943 0.8571078681398887 0.3913852731836122 1.0 0.602629851666207 39 Q96HY6,P07948,Q9P0J0,Q9UL46,P23396,O43464,Q96F07,P51572,Q13794,O95831,Q9Y3D6 11 +Cholesterol efflux 0.5016016039514634 0.8566457323358664 0.3916407032132629 1.0 0.602629851666207 8 O15118,P04114,Q8WTV0 3 +Antigen processing and presentation 0.3949920210230177 0.8566064921342544 0.3916623965743242 1.0 0.602629851666207 24 Q9BZG1,Q9NVJ2,P50570,Q03518,Q9UIQ6,Q9NZ08,P04439,P10321 8 +Positive regulation of apoptotic signaling pathway 0.3879304616200125 0.8554481694275349 0.3923030864535759 1.0 0.6034707905369383 29 O43464,P51572,Q13794,Q9Y3D6,Q9NQX7 5 +Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator 0.392429634422515 0.8519107923640361 0.3942636063432192 1.0 0.6060502917649965 2 Q9UNS2 1 +Tube development 0.297878975398152 0.8512645293919638 0.3946224240105245 1.0 0.6063725055681722 131 Q9UNS1,P42785,P46379,Q9H6E4,O94813,P80723,O60476,P09601,Q9NZ08,Q9Y4G8,P23634,Q96AY3,P42892 13 +Regulation of dna methylation 0.4891346761002562 0.8511925203607293 0.3946624170406263 1.0 0.6063725055681722 10 Q8NB78,O75844,Q03164,Q96KQ7 4 +Regulation of cytoplasmic transport 0.4801092887280031 0.8505093031400923 0.3950419903884203 1.0 0.6066648678461367 11 Q13614,P53367 2 +Response to arsenic containing substance 0.4704254347000725 0.8485875303993636 0.3961108479844375 1.0 0.6078694123965153 12 P09601 1 +Negative regulation of telomere capping 0.4536209057377822 0.8473660568180991 0.3967911178434917 1.0 0.6084535967368132 4 P18887 1 +Proteasomal protein catabolic process 0.298735667426486 0.8472190271515956 0.3968730499308048 1.0 0.6084535967368132 150 P46379,P49721,Q9UL46,Q9NWU2,Q9BZK7,Q16763,Q9Y5A7,Q99436,P28070,Q96PU5,P28074,Q92530,Q96HY6,Q96J02,Q92575,P20618,Q13794,Q9UJX3,Q8N163,P60520 20 +Negative regulation of secretion 0.4441296731776789 0.8456461136924942 0.3977501924221651 1.0 0.6092183353467332 15 P09601,Q16836,Q6WKZ4,Q16850,P04899,P30040 6 +Dicarboxylic acid transport 0.4245374459690099 0.8445722875529127 0.3983496871822125 1.0 0.6094084713217142 18 P41440,Q8TDW0,Q15758,Q9BQT8 4 +Positive regulation of plasma membrane bounded cell projection assembly 0.3949475749899233 0.8436405373672544 0.3988703046560462 1.0 0.6099138007741547 22 Q16625,P50570 2 +Early endosome to golgi transport 0.5038132054901605 0.8428278497289731 0.3993247299424634 1.0 0.6104204928036192 7 Q13190,O60499 2 +Regulation of rna splicing 0.3248393796374883 0.8396906171704026 0.4010818761834542 1.0 0.6122731189178237 89 P52597,P61978,Q86U06,O75312,P62995,P98175,Q8WVV9,Q13247,Q9H0G5,Q9NR56,Q5BKZ1,Q15637,Q13573,O75525,Q9NW64,O75494,P55795,P98179,Q16629,P08621,Q8IY67,P38159,Q92879,P31942,Q14011,P31943,Q96E39,Q06787,P51114,O00422,Q9Y5S9,O95319,P35637,Q9UKA9,Q07666,Q96PU8 36 +Ventricular septum morphogenesis 0.4520015692220361 0.8391539751915831 0.4013829106949176 1.0 0.6124765003941506 4 O94813 1 +Regulation of synaptic transmission glutamatergic 0.4519261897053946 0.838771928785886 0.40159730595267 1.0 0.6124765003941506 4 P19022,Q00535,Q8NBU5 3 +Amino acid import across plasma membrane 0.5074728374872094 0.8378693262653752 0.4021040977078314 1.0 0.6129577327722234 6 P30825 1 +Regulation of dna methylation dependent heterochromatin assembly 0.4918332722894888 0.8358074542336523 0.4032632322843641 1.0 0.614179151440042 9 Q8NEY8,Q15047 2 +Photoreceptor cell development 0.4513322439578828 0.8357623358674802 0.4032886190969011 1.0 0.614179151440042 4 P54802 1 +Cell migration involved in sprouting angiogenesis 0.5020389713250308 0.8345003402391185 0.4039990957096728 1.0 0.6151150127076017 7 P09601 1 +Negative regulation of cytokine production 0.3926950214860564 0.8338365011327731 0.4043731234531671 1.0 0.6155382857598672 23 Q96RT1,Q96J02,Q06481,P09601 4 +Mitochondrial protein processing 0.5058116887493589 0.8302262296020324 0.4064108879447849 1.0 0.6181997607323378 6 Q9UJZ1,Q10713 2 +Endosomal transport 0.3247999447398257 0.8298607005592695 0.4066175465755166 1.0 0.6182207005571778 61 Q96FZ7,O00203,Q4J6C6,Q14203,P40616,Q15904,O60826,P42566,P14373,O60749,Q13190,O95249,Q9NVJ2,Q6IAA8,O75503,O60271,Q96D71,Q93009,P53367,Q9H4M9,Q92538,O60499 22 +Acetyl coa biosynthetic process 0.4668302948835547 0.8295868856466136 0.4067723939942538 1.0 0.6183060936509086 12 O95563 1 +Positive regulation of response to wounding 0.4846264859891059 0.8286758370981405 0.4072878620925606 1.0 0.6187995250090813 10 Q16625,Q92766 2 +Basement membrane assembly 0.4187263337156113 0.8283775204118143 0.4074567332505687 1.0 0.6189093981365273 3 O60568 1 +Meiosis ii cell cycle process 0.4186541757895951 0.8279892551764686 0.4076765850072159 1.0 0.619096638212806 3 O60566 1 +Plasma membrane repair 0.5050672529549004 0.8268036513332541 0.4083483601526803 1.0 0.6199699167642541 6 Q9NVJ2,P35579 2 +Entry into host 0.3804551365081968 0.8265950147535991 0.4084666439309881 1.0 0.6200026492061648 31 Q15758,O15118,Q14108,Q8WTV0,P02786 5 +Cellular response to hydrogen peroxide 0.4215782074908828 0.8263247490837848 0.4086198978451754 1.0 0.6200884339932704 18 Q99720 1 +Positive regulation of epithelial cell proliferation 0.4279371068539729 0.8242556529326939 0.40979431090879 1.0 0.6211353825787052 17 Q92766,P09601 2 +Cell killing 0.4070962682273318 0.82302416142986 0.4104942536940552 1.0 0.6219021900682803 20 Q9NVJ2,P07437,P46108,P60602,O15400,P04439 6 +Dna unwinding involved in dna replication 0.4399639784931538 0.821726374728459 0.4112326448006553 1.0 0.6225794173765236 15 Q96RR1,Q9BRT9,Q9BRX5,P25205 4 +Mitochondrial proton transporting atp synthase complex assembly 0.4480414373583568 0.8191107748355767 0.4127232149703643 1.0 0.6245282665441224 4 Q96HJ9,Q15070,Q9BUB7 3 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.4823975642881574 0.8175680688965429 0.4136038666396444 1.0 0.6253018599476298 10 P67809,Q9NZI8,O60506,P11940,Q9H2U1 5 +Negative regulation of g protein coupled receptor signaling pathway 0.5029714746857679 0.8171772409848685 0.4138271467215881 1.0 0.6254732399163829 6 P23634,P50570 2 +Threonine metabolic process 0.4165048543689357 0.8164344998252872 0.4142516714838118 1.0 0.625819753526098 3 O43175,P52758 2 +Maintenance of synapse structure 0.4471062017872776 0.814385927050083 0.415423898091972 1.0 0.6269975748825543 4 Q9BRK5,Q14203 2 +Regulation of small gtpase mediated signal transduction 0.3762351634061324 0.8094568504985082 0.4182524129536609 1.0 0.6306200015996711 32 O94813,P50570,Q14344,P41440,Q92538,P46108,P35241,Q9NUQ9,Q96RT1,Q92974 10 +Ubiquitin dependent erad pathway 0.3718331482765952 0.808727321680404 0.4186720090230273 1.0 0.6310104815042571 34 Q96CS3,P46379,Q9Y385,Q6NTF9,Q92575,Q9UBU6,P51572,Q9Y679,Q8IXB1,O43765,Q96DZ1,Q96A33 12 +Post chaperonin tubulin folding pathway 0.4457065169827793 0.8073210823858329 0.4194815207958955 1.0 0.6320819342505148 4 O75347,O75695 2 +Negative regulation of supramolecular fiber organization 0.3553800468252219 0.8053405001104957 0.420623216706272 1.0 0.6333556070207197 40 O94813,Q13045,P29372,P28289,Q9UEY8,P35241,O60925,Q92974,P35611 9 +Negative regulation of rna splicing 0.4179310450175242 0.8038923604287392 0.4214591425038025 1.0 0.6340185645269595 18 P61978,O75494,O00422,Q9UKA9,P98175,Q16629,Q13247,P38159 8 +Positive regulation of protein binding 0.4240460047851647 0.8009112847069219 0.4231830066866775 1.0 0.6361639476692315 17 P41440 1 +Folic acid containing compound metabolic process 0.4418581878784759 0.8000592129572396 0.4236764909923152 1.0 0.6364580049825967 14 P41440 1 +Response to testosterone 0.4991622668151581 0.799716217954369 0.4238752343524978 1.0 0.6365276360226391 6 Q13126 1 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.3817994464313817 0.7986059469579435 0.4245189382387284 1.0 0.6365276360226391 28 Q9UQ84,O15400,O96028,Q9NQT5,Q9NUQ9,P02786,P04439 7 +Cellular response to osmotic stress 0.4608840881629129 0.7982664798371686 0.4247158657205658 1.0 0.6365276360226391 12 Q9BUP0,Q8TDW0,P16989 3 +Glucose import 0.4837300559556113 0.7963223739226636 0.4258446842941996 1.0 0.6377421151839858 9 P31751,Q16625 2 +Negative regulation of defense response 0.3861722455203001 0.7949535391825227 0.4266405288156909 1.0 0.6383194431516979 24 P07948,Q96J02,Q14166,P46108,P28070,P04439 6 +Transforming growth factor beta receptor signaling pathway 0.3950616642831888 0.7924199924144149 0.4281158259447339 1.0 0.6399772491384667 21 P50570,Q92896 2 +Mitochondrion localization 0.4403652815907578 0.7917173603856555 0.4285254974248356 1.0 0.6400697022827093 14 O00429,O75153,Q9BUK6,P07196 4 +Positive regulation of fat cell differentiation 0.4425334166745335 0.7913345940270323 0.428748766293016 1.0 0.6401769373254677 4 Q92766 1 +Lactation 0.4500634509119938 0.7908943655019591 0.4290056366606478 1.0 0.6404113020481492 13 Q15648,Q04656,P35670,Q9UNS2,Q13505,P07741,P00403,Q99808 8 +Protein processing 0.3409128494420279 0.7895267172777183 0.4298042206829668 1.0 0.641155469997165 47 O75844,O75787,P17655,O43464,Q96F07,Q5JRX3,Q96TA2,O75503,Q15392,Q5TDH0,O75976,Q10713,Q9UJZ1,P42892,Q92896 15 +Membrane fusion 0.3469822944034744 0.787518247544577 0.4309785507584407 1.0 0.6421600442495594 42 Q9BZG1,P31751,O75396,Q12981,O15400,Q9P2W9,O60499,Q13190,Q9H267,O14653 10 +Regulation of feeding behavior 0.3811064380459361 0.7869977345999235 0.4312831923049811 1.0 0.642330792993968 2 P40763 1 +Adenylate cyclase modulating g protein coupled receptor signaling pathway 0.4491783328596742 0.7861073092601574 0.4318046225245293 1.0 0.6429425389970345 13 Q9Y4G8,P23634 2 +Positive regulation of t cell mediated immunity 0.4683576561582001 0.7852847597304786 0.4322866293171556 1.0 0.6433488212436229 5 O15400,P04439 2 +In utero embryonic development 0.3164413213837782 0.7852684629207294 0.4322961822511988 1.0 0.6433488212436229 97 P16989,Q9H0G5,Q9NR56,O43819,P67809,Q9Y5P4,P14635,Q9BZK7,P23786,O43772,Q9BRT9,P04114,Q96AY3,Q08J23 14 +Fatty acid beta oxidation using acyl coa oxidase 0.4914572434590005 0.7850416126185713 0.4324291710317556 1.0 0.6433488212436229 7 O15254,O14734 2 +Trna transport 0.468157835257825 0.7843284314270392 0.4328474208314774 1.0 0.643483207014637 5 P67809 1 +Positive regulation of signaling 0.2849788551509197 0.7841213989527306 0.4329688802192082 1.0 0.643483207014637 227 O95429,Q9NWU2,P29372,Q9BZK7,Q9Y4G8,Q969T9,Q92734,P42892,P02786,Q9Y3D6,Q96K76,O95793,Q13641,P23396,P41440,Q7Z434,Q9H1E3,Q9UMX5,Q9UQB8,Q9NX40,P04899,Q6IAA8,O95563,O43464,Q96F07,P09601,Q06481,Q13794,Q96EE3,Q96JB5,Q12824,P05771,Q9NQX7,P07948,Q8N163,Q9BZG1,O95071,O75787,P51572,Q05086,Q96RT1,P18615 42 +Regulation of epidermal growth factor activated receptor activity 0.4409193913887854 0.783219345776653 0.4334983163202603 1.0 0.6439685301536197 4 Q96FZ7,Q9BRG1,Q9UNH7 3 +Negative regulation of epidermal growth factor activated receptor activity 0.4409193913887854 0.783219345776653 0.4334983163202603 1.0 0.6439685301536197 4 Q96FZ7,Q9BRG1,Q9UNH7 3 +Muscle adaptation 0.4484451751487797 0.7821448293528626 0.4341294634500752 1.0 0.6447566869126464 13 P09601,Q13555 2 +Regulation of lipid catabolic process 0.4806035864613013 0.7811509875184001 0.4347136965101565 1.0 0.6451759191086139 9 P31751,Q8WTV0 2 +Mitotic g2 dna damage checkpoint signaling 0.4569778049429689 0.7777699875112092 0.4367046241095706 1.0 0.6475310295032034 12 P53350,Q6NUQ1,P38398,Q96JB5,P06493,Q9NXR7 6 +Extrinsic apoptotic signaling pathway 0.3675496204488175 0.7750562122253974 0.4383064443525697 1.0 0.6494554573046629 34 Q9P0J0,P09601,Q13794,O95817,Q9NQX7 5 +Regulation of protein secretion 0.3546566662510346 0.7739060725592936 0.4389863382604035 1.0 0.649666296047474 39 Q32P28,O95563,Q6WKZ4,Q16850,P53367 5 +Response to alkaloid 0.3994716341291191 0.7737868539670614 0.439056847812427 1.0 0.649666296047474 20 P50570,P50416,P63151,Q05086,P28161 5 +Positive regulation of synaptic vesicle recycling 0.3785182788741594 0.7722572580843561 0.4399620749646344 1.0 0.6504051892350801 2 Q96CW1 1 +Positive regulation of synaptic vesicle endocytosis 0.3785182788741594 0.7722572580843561 0.4399620749646344 1.0 0.6504051892350801 2 Q96CW1 1 +Regulation of synaptic vesicle endocytosis 0.3785182788741594 0.7722572580843561 0.4399620749646344 1.0 0.6504051892350801 2 Q96CW1 1 +Regulation of protein exit from endoplasmic reticulum 0.4837301985264357 0.7713854572230952 0.4404784924704932 1.0 0.6510184774581188 8 Q96DZ1,P51572,Q8NBM4 3 +Protein import 0.3223912588025884 0.7709664909487188 0.4407267937582566 1.0 0.651235303824441 80 Q99653,O60830,Q9NS69,Q99595,Q15388,O00459,Q9UI26,Q7Z434,P60602,O00410,O95831,O95817,Q15717,Q7Z3B4,O75381,O43615,Q06481,Q99567,Q96DA6,O95071,Q8N1F7,O95373,P57740,P06493,Q96P70 25 +Muscle cell apoptotic process 0.4462936764396316 0.77053126344688 0.4409848172451913 1.0 0.651466392842055 13 P17655,P09601,Q9NQ88,P42771,P98175,O95817 6 +Regulation of hormone levels 0.320565687288286 0.7696323047888706 0.4415180365020597 1.0 0.6519536083801434 64 P07948,O75844,O75787,Q6NUM9,Q9HB40,O95563,P50416,Q53GQ0,Q13555,Q6WKZ4,Q9BTZ2,O95470,P42892 13 +Regulation of protein depolymerization 0.3791632495009795 0.7694414360046041 0.4416312982335 1.0 0.6519706636749735 27 Q13045,P29372,P28289,Q9UEY8,P35241,Q92974 6 +Negative regulation of protein containing complex assembly 0.3705300570087692 0.765812620037131 0.4437878039980805 1.0 0.653433313655671 32 O94813,Q13045,P28289,P45880,Q9UEY8,P35241,P35611 7 +Response to oxygen containing compound 0.2737166898207894 0.7646018883630388 0.4445086443567871 1.0 0.6536612072752176 257 O94813,Q9P0J0,Q13126,Q86U42,Q99720,P11717,Q9HCL2,Q9Y4G8,Q96KQ7,P04114,Q969T9,P02786,Q15388,P48163,O00459,P17655,P23396,P49321,P60602,Q16836,Q6IQ22,Q9H1E3,P62993,P38398,Q9UQB8,P23634,O95831,P04899,Q5KU26,Q92974,Q9UNS1,Q6IAA8,P08670,P50570,O95563,O43464,P09601,Q06481,Q96RR1,O43823,Q99808,Q8WTV0,Q8TBX8,Q9BRK5,Q12824,P05771,P33527,P07948,P50416,P31751,P46108,Q9HCD5,P09960,Q05086,Q86X55,Q96RT1,P07196 57 +Canonical wnt signaling pathway 0.3615407733186652 0.7645995856164952 0.4445100159926167 1.0 0.6536612072752176 36 Q8N163,O95071,O75787,Q13641,Q8NBM4,Q9NWU2,Q9BZK7,Q96K76 8 +Positive regulation of dna binding transcription factor activity 0.3682831131235869 0.7640178839388513 0.4448565851736672 1.0 0.6538708348918154 33 Q96HY6,P60900,P23396,P41440,Q12824,P02786,P05771,Q92974 8 +Suppression of viral release by host 0.406472491909389 0.7627876229507876 0.4455900637211254 1.0 0.6541089645703583 3 Q14258,P14373 2 +Regulation of dna demethylation 0.4064724919093891 0.7627876229507876 0.4455900637211254 1.0 0.6541089645703583 3 Q93009,Q93008 2 +Regulation of neural precursor cell proliferation 0.4351482874794735 0.7626514735217178 0.4456712780031027 1.0 0.6541089645703583 14 P07948,Q06481,P04899,Q9UKA9 4 +U4 snrna 3 end processing 0.4866324402648761 0.762621965919071 0.4456888806487424 1.0 0.6541089645703583 7 Q96B26,Q5RKV6,Q9NQT5 3 +Liver regeneration 0.4710270687543717 0.7611930579581816 0.4465417640546838 1.0 0.6549784021041447 10 P09601 1 +Response to radiation 0.3219361162991537 0.7609267615625792 0.4467008130832763 1.0 0.6549784021041447 74 Q14011,P22830,P50570,P31751,P12956,Q9BRK5,Q96K76,Q9NXR7 8 +Response to increased oxygen levels 0.4755657658198135 0.7567866257624011 0.4491777066797042 1.0 0.6575083580308071 9 P00846 1 +Dna synthesis involved in dna repair 0.4611725282609034 0.7537975067278716 0.450970821340098 1.0 0.6591036761655259 11 P49005 1 +Negative regulation of phosphatase activity 0.4616949600583335 0.7534861464605314 0.4511578330625563 1.0 0.6591036761655259 5 O95429 1 +Regulation of myelination 0.4799286486765145 0.7533994036227112 0.45120994106287 1.0 0.6591036761655259 8 Q13614,O75312,O75746 3 +Learning 0.4221649278578291 0.7532632642890714 0.451291729303116 1.0 0.6591036761655259 16 Q05086,Q13641 2 +Atp synthesis coupled electron transport 0.3407404862437253 0.7515432529556252 0.4523257803488283 1.0 0.6595960871434065 44 Q7KZN9,O95182,P06493,P51970,P14635,P00403,O75380,O43678,Q9Y375,P03886,P13073,O43676,O95168,O96000 14 +Negative regulation of protein localization 0.3457854308814481 0.7490480833501536 0.4538282248426417 1.0 0.6604355324106952 41 P30040,Q9Y385,Q8NBM4,O95429,Q8N183,Q16836,Q6WKZ4,Q96PU5,Q10713,Q16850,Q96DZ1,O95817 12 +Lymphocyte homeostasis 0.4684528382797589 0.7485045600346084 0.4541558755932975 1.0 0.6607215530079521 10 Q9HCL2,Q13794 2 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.4322137963724026 0.7463643921151907 0.455447323126573 1.0 0.6624500433949019 14 O95831 1 +Regulation of anatomical structure size 0.3196156454466947 0.7456041776290365 0.4559065585447124 1.0 0.6628565242337701 83 O94813,O95429,P28289,P42892,Q13045,P62993,O96011,P35241,Q9UQB8,Q8N0X7,P35611,P50570,Q4KMQ2,Q96F07,Q15375,Q9P2J5,Q9HB40,P51790,Q9UEY8,P07196 20 +Ephrin receptor signaling pathway 0.4872352140643515 0.7453748339751821 0.4560451531128797 1.0 0.6628565242337701 6 P07948,P46108 2 +Regulation of protein catabolic process 0.2962806342124454 0.7439868909765475 0.4568844058448351 1.0 0.6637871807491825 118 Q96HY6,Q8N163,Q96J02,Q8NHS3,P46379,Q9P0J0,Q9UL46,Q9Y5A7,P60520,P51572,Q05086,Q96PU5,P35241,Q16850,Q9H2J4,Q92530 16 +Cerebellar cortex development 0.4500276960240256 0.7414759979660736 0.4584048796515185 1.0 0.6653929525738754 12 Q5KU26 1 +Enzyme linked receptor protein signaling pathway 0.3114669647225471 0.74072415821946 0.4588607083930691 1.0 0.6659038127234714 100 P11717,Q9Y4G8,Q92896,O00459,O95470,Q9UQB8,Q8N0X7,P04899,P08670,P50570,Q96F07,Q9UIQ6,Q15375,Q06481,Q8TBX8,P05771,P07948,P31751,P46108,Q6PIU2,Q96RT1 21 +Regulation of microtubule depolymerization 0.4816098332149158 0.7393817339586636 0.4596752307205261 1.0 0.6666330834657402 7 P29372,Q8WWK9,Q92974 3 +Regulation of cellular ketone metabolic process 0.4133931404434984 0.7374122911650189 0.4608716631540306 1.0 0.6680658889229616 17 P49748,Q15118,P50416,P31751,P23634 5 +Golgi to endosome transport 0.4810830122836087 0.7369502438325232 0.4611526078588146 1.0 0.6683220023456933 7 Q96RL7,Q92538,Q8N2H4 3 +Actin filament depolymerization 0.4002878973593638 0.7356112780330878 0.4619672970965913 1.0 0.6690488871191032 19 Q9UEY8,P35241,Q13045,P28289 4 +Positive regulation of smooth muscle cell proliferation 0.4754850626971172 0.7324536688379508 0.4638917116187697 1.0 0.6713808696040447 8 P09601 1 +Negative regulation of mapk cascade 0.3711486156324285 0.7317610631035383 0.4643144184853047 1.0 0.6717662522839044 29 Q96S59,O00459,Q96J02,P07948,Q96KB5,P78318,P30086,Q99956,Q96P70,P41240,Q96JB5,P30153,P15311,Q13526 14 +Nuclear transcribed mrna catabolic process exonucleolytic 3 5 0.4700960843982816 0.7304580181238155 0.4651102656242403 1.0 0.6725370635351636 9 Q96B26,Q5RKV6,Q9NQT5 3 +Ovulation cycle 0.4564774097634098 0.7287213597215108 0.4661721242995056 1.0 0.673214696901567 5 O94813 1 +Chaperone mediated protein complex assembly 0.4642136186784402 0.7276762156025346 0.4668118131944929 1.0 0.6739332708506081 10 O95456 1 +Regulation of metal ion transport 0.3261717399998584 0.7274863120767716 0.4669280974396366 1.0 0.6739493592857623 52 P07948,Q99653,Q13586,P50570,Q4KMQ2,P46939,Q12955,O43865,P21796,Q13555,P54652,Q06787,Q96PU5,P27105,P23634,P04899,P28161 17 +Negative regulation of ion transmembrane transport 0.4287630516965017 0.7272738728717557 0.4670582000696186 1.0 0.673985381009963 14 Q12955,P21796,Q06787,Q96PU5,P28161 5 +Positive regulation of cell cycle g1 s phase transition 0.417539455263084 0.7264730984663695 0.4675487933175515 1.0 0.6745414731410095 16 Q96HY6,Q96DY7 2 +Regulation of secretion 0.3178334760316746 0.7240284093100705 0.4690482940110829 1.0 0.6759482704455738 83 O95563,Q32P28,P09601,Q4J6C6,Q6IQ22,Q6WKZ4,Q16850,P53367,P05771 9 +Regulation of neuron migration 0.4824962223895335 0.7239399248140663 0.4691026176494033 1.0 0.6759482704455738 6 Q9Y4G8 1 +Antigen receptor mediated signaling pathway 0.404695445369881 0.7231093703968247 0.4696126928291841 1.0 0.6759482704455738 18 P07948,P23396,P04439,Q07666,Q9UJZ1,P15311,P05771 7 +Positive regulation of transferase activity 0.3168224324100531 0.7230249229091598 0.4696645724209893 1.0 0.6759482704455738 86 P07948,P23396,Q86U42,P12956,Q9BRX5,Q99627,Q13432,Q9BRT9,Q9Y4G8,P23634,Q96M27,P14635,Q16763,Q9BTE7 14 +Axonemal dynein complex assembly 0.3697832416693613 0.7228218840569954 0.4697893205670875 1.0 0.6759482704455738 2 Q9NVR5 1 +Inner dynein arm assembly 0.3697832416693613 0.7228218840569954 0.4697893205670875 1.0 0.6759482704455738 2 Q9NVR5 1 +Outer dynein arm assembly 0.3697832416693613 0.7228218840569954 0.4697893205670875 1.0 0.6759482704455738 2 Q9NVR5 1 +Sensory perception 0.3663086440352841 0.7199754349977905 0.471540120426043 1.0 0.677858751274038 31 Q9BRK0,Q9H6K4,P62072,P23634,Q14108,P50897 6 +Cellular homeostasis 0.2908625910833947 0.718803142915514 0.4722622209082507 1.0 0.6786261942714755 147 Q9HD20,P0CG08,Q9HC07,P50897,Q9UJZ1,P02786,Q9Y3D6,Q16763,O00459,Q96AX1,Q9Y487,Q96PU5,P23634,Q9Y6M7,O95817,Q4KMQ2,O95563,P09601,O75503,Q96RR1,Q99808,Q12824,P05771,P28161,P07948,O43819,P51572,P51790,Q05086,Q93050 30 +Intracellular receptor signaling pathway 0.3212427650839085 0.7164201421403033 0.4737319613592714 1.0 0.6803992543833587 54 Q96HY6,Q96J02,P42785,Q05086,Q9NUQ7,Q96RT1 6 +Erad pathway 0.3477105449608 0.7155431993380379 0.4742734572760301 1.0 0.6807252818773372 39 Q96CS3,Q8WU17,P46379,Q9Y385,Q8NBM4,Q6NTF9,Q92575,Q9UBU6,P51572,Q8IXB1,O43765,Q96DZ1,Q96A33 13 +Regulation of phagocytosis 0.4155085560876963 0.7147530251545844 0.4747616662941454 1.0 0.6809626943265769 16 Q06481,Q8WTV0,P50570,Q08722 4 +Positive regulation of lyase activity 0.3973046662088759 0.7142430164035335 0.4750769216032684 1.0 0.6812624312028973 3 Q13586 1 +Glycerolipid biosynthetic process 0.3296575663245491 0.7121605496025935 0.4763653630665341 1.0 0.6821930380666389 49 Q13614,O00459,Q9Y2B2,P17655,Q8NCC3,Q9HCL2,Q10713,Q8WTV0,Q9NPH0,Q8TBX8,O60762 11 +Protein maturation 0.3171504012752121 0.712047571997059 0.476435318065846 1.0 0.6821930380666389 70 O75844,O75787,P17655,O43464,Q96F07,Q5JRX3,Q96TA2,O75503,Q9NRN7,Q15392,Q5TDH0,Q86UY6,O75976,Q10713,Q9UJZ1,P42892,Q92896,P49366 18 +Cell projection assembly 0.3168292756817927 0.7118840709942673 0.4765365667899959 1.0 0.6821930380666389 83 O94813,P50570,O95429,Q16181,Q16625,Q9NR77,A6NIH7,Q9Y4G8,Q66K14,P84095 10 +Actin mediated cell contraction 0.4259286836605314 0.7116464822578198 0.4766837156787014 1.0 0.6821930380666389 14 Q9UM22,Q96PU5 2 +Negative regulation of intracellular transport 0.3962498285535464 0.7105109162811931 0.4773873639565349 1.0 0.6826283387201191 19 Q9Y385,Q8NBM4,O95429,Q96DZ1,P53367,O95817 6 +Dna integrity checkpoint signaling 0.361265890209274 0.7099926896964261 0.4777086694613546 1.0 0.6828975404208927 33 Q9UNS1,Q8N163,Q9BXW9,P53350,Q13564,Q9Y619,P38398,Q96JB5,P06493,Q9NXR7 10 +Positive regulation of adaptive immune response 0.4349035578740068 0.7094478886570958 0.4780465788772803 1.0 0.68307591854734 13 Q9NQT5,O15400,O96028,Q9NUQ9,P02786,P04439 6 +Response to tumor necrosis factor 0.3679006208338922 0.7080681929677418 0.4789029106333404 1.0 0.6839206619418307 29 P16989,Q9Y5A7,P23396,O95429,P04114,Q96RT1,P78318 7 +Response to transforming growth factor beta 0.3705488552514998 0.707906177342667 0.4790035233342515 1.0 0.6839206619418307 27 Q06481,P50570,Q92896 3 +Purine deoxyribonucleotide metabolic process 0.4520435867464522 0.7077800176434617 0.4790818772762417 1.0 0.6839206619418307 5 P55263 1 +Artery morphogenesis 0.478876863551979 0.7076361350240633 0.4791712469236757 1.0 0.6839206619418307 6 Q96AY3 1 +Cellular response to abiotic stimulus 0.3150195710776255 0.7046367730622514 0.4810363078115363 1.0 0.6858191132277464 65 Q9BUP0,Q8TDW0,P16989,O75844,P50570,P31751,P12956,Q9H1E3,P62993,O95817,Q92974,Q96K76,Q9NXR7 13 +Apoptotic signaling pathway 0.288655498627938 0.7027305847399873 0.4822236636095076 1.0 0.6873250843765147 131 P46379,Q9P0J0,Q9HBM6,P61978,Q9Y3D6,Q96K76,Q15118,P23396,Q8IXB1,P45880,O95470,O95831,P04899,O95817,P16989,O43464,P09601,Q13794,Q9NQX7,Q8N163,P51572 21 +Endoplasmic reticulum membrane organization 0.4590848700293179 0.7025968019374769 0.4823070560882314 1.0 0.6873250843765147 10 Q12981,Q00765,Q8NHH9,Q9P2W9 4 +Mammary gland development 0.3741038323740385 0.7020175620623884 0.4826682112348877 1.0 0.6875340520034734 22 Q92766,P31751,Q13505,P00403,Q99808 5 +Regulation of cytoskeleton organization 0.2986624504314966 0.7014124661233645 0.483045644465867 1.0 0.6877660108898729 113 Q96FZ7,O94813,O95429,Q13576,P29372,P28289,P36405,P84095,P17655,Q13045,P23396,Q16625,P62993,P38398,Q9UQB8,P35241,Q92974,P35611,Q08722,Q96F07,Q9NUQ9,P53367,P53350,P46108,Q9NUL3,Q9UEY8 26 +Positive regulation of ubiquitin protein transferase activity 0.457770267118061 0.6961907918842226 0.4863093535145739 1.0 0.6913379809333375 10 Q9BTE7 1 +Negative regulation of response to dna damage stimulus 0.3717373260678331 0.6951818388484319 0.4869413522383117 1.0 0.6917761675194101 24 Q8N163,O95071,Q9HBM6,P23396,Q96K76 5 +Regulation of dna templated transcription in response to stress 0.4409622478694863 0.6945150356018316 0.4873592749362281 1.0 0.6918929875887988 12 P09601 1 +Positive regulation of intracellular signal transduction 0.2872579204354961 0.6941487643054627 0.4875889199174579 1.0 0.6918929875887988 124 O95429,P29372,Q9Y4G8,Q92734,P02786,Q9Y3D6,Q13641,P23396,Q7Z434,Q9UMX5,P04899,Q6IAA8,P09601,Q13794,Q96EE3,Q96JB5,P05771,P07948,Q8N163,P51572,Q05086,Q96RT1,P18615 23 +Positive regulation of intracellular protein transport 0.3209307853117331 0.6940175233670094 0.4876712196452719 1.0 0.6918929875887988 53 Q99653,P50402,O75312,P55786,Q9Y3D6,O00459,Q12955,O00410,Q7Z434,Q9NW64,O95817,Q99496,O43464,P27105,O95071,P31751,P51572,Q9Y282,P06493 19 +Regulation of epithelial cell migration 0.3502904126516881 0.6936824753261577 0.487881358528579 1.0 0.6920379526816092 37 P42785,O94813,P09601,Q8WTV0 4 +Regulation of lymphocyte differentiation 0.4168358406350343 0.6905058001591512 0.4898761636965376 1.0 0.6945600993795192 15 Q9BXW9,P12956 2 +Positive regulation of receptor mediated endocytosis 0.4663499180897698 0.6896843400591524 0.4903927159213468 1.0 0.6949850340605424 8 P61978,P50570 2 +Regulation of cell differentiation 0.2880571436792799 0.6892687709150472 0.4906541464793192 1.0 0.6950876274519542 184 Q8WUJ1,O94813,P12956,Q9Y4G8,P04114,Q08J23,Q8N4Q0,Q92896,P67809,Q9UQB8,Q8N0X7,Q9NX40,Q92974,Q9GZS3,Q96J02,P50570,Q15375,Q9Y2G5,Q06481,Q9BYT8,P07948,Q9BXW9,Q92766,P46108,O43290,Q9H6W3,Q86X55,Q96G23,P07196 29 +Cytoplasmic translational initiation 0.4049929551021567 0.6878457728349037 0.4915499080680718 1.0 0.6961370223643009 17 P55010 1 +Interstrand cross link repair 0.4477249256141909 0.6874813038891922 0.4917794783964542 1.0 0.696180754532083 5 Q9BXW9 1 +Postsynapse organization 0.3618720464987516 0.6868815048492821 0.4921574027919952 1.0 0.6964081571515872 31 Q13614,Q9Y4F1,Q05086,Q15375,Q9UQB8,P07196 6 +Positive regulation of protein export from nucleus 0.4608061011770956 0.686072656977779 0.4926672923227508 1.0 0.6969757986733244 9 Q92688,Q9NW64,P50402,O95817,Q05D32 5 +Positive regulation of axonogenesis 0.4555695358064598 0.6854881204859824 0.4930359544132157 1.0 0.6973434394944202 10 O94813 1 +Regulation of fat cell differentiation 0.465384347410772 0.6851884234017734 0.4932250280623507 1.0 0.6973454595985074 8 Q92766,Q8N4Q0 2 +Response to estradiol 0.4386703385390657 0.6827183732298806 0.4947848175205607 1.0 0.6984300110783515 12 O95831 1 +Maintenance of cell polarity 0.4205861521503023 0.6820987460255838 0.4951765134824728 1.0 0.6987613282700861 4 Q03001 1 +Pentose metabolic process 0.4205244415668422 0.6817954251056387 0.4953683175018464 1.0 0.6987613282700861 4 Q7Z4W1,P11413,P52209 3 +Regulation of dna directed dna polymerase activity 0.468802564386 0.6806373250865572 0.4961010031616237 1.0 0.6993618038992968 7 Q9BRX5 1 +Positive regulation of rna binding 0.4726271460965463 0.6796307733257697 0.49673827934628 1.0 0.6996467524960789 6 O15371,P60228,Q06787,Q04637,P50750 5 +Regulation of intrinsic apoptotic signaling pathway 0.3194037900302813 0.6788922849080827 0.4972061144731945 1.0 0.7001518439747753 53 Q8N163,P16989,Q9P0J0,Q9HBM6,P23396,O43464,P51572,P61978,P45880,Q13794,Q9Y3D6,Q96K76 12 +Cellular response to chemical stress 0.3144595092758194 0.6784603661923231 0.4974798453105924 1.0 0.7002713925906028 81 Q7Z2K6,Q9BUP0,P16989,Q9BXW9,Q8TDW0,O95793,Q15118,P23396,O43464,Q99720,P60602,P09601,Q8N0U8,O95831,Q92974,P33527 16 +Negative regulation of cell cycle process 0.3133327372127149 0.6783510861355673 0.4975491148593407 1.0 0.7002713925906028 67 Q9UNS1,P14635,Q9Y619,Q96DY7,Q08J23,Q96K76,Q9NXR7 7 +Regulation of peptidase activity 0.3148186809942002 0.6782412360683479 0.4976187508970664 1.0 0.7002713925906028 77 Q96HY6,P07948,P78318,Q9P0J0,Q9UL46,P23396,O43847,O43464,Q96F07,P51572,Q15392,Q15375,Q06481,Q13794,O95831,Q9Y3D6,Q96K76,Q92530 18 +Mitotic nuclear membrane disassembly 0.4191194098887122 0.6748959871746549 0.4997418501860891 1.0 0.7026995936715031 4 P05771 1 +Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.4450224348265645 0.6748316129117519 0.4997827531276728 1.0 0.7026995936715031 5 O43464,P30154,P30153 3 +Regulation of transporter activity 0.3454280473200541 0.6745856605395181 0.4999390458512489 1.0 0.702765193839146 38 Q13586,P50570,P46939,Q12955,O43865,P54652,Q96PU5,P27105,Q03164,P08183,P28161 11 +Phosphatidylglycerol metabolic process 0.4190972742032001 0.6741954118999831 0.5001870861975117 1.0 0.7029597067586165 14 Q8NCC3 1 +Cell cycle phase transition 0.2868647147493984 0.6739218585012773 0.5003609944661878 1.0 0.7030499724963313 131 Q9UL46,Q96DY7,Q08J23,Q16763,Q96K76,P35241,P23634,Q96HY6,Q9UNS1,P50570,Q06481,O43823,Q9UJX3,P14635,P08183,Q9NXR7,Q8N163,Q9Y619,Q9ULX6 19 +Telencephalon glial cell migration 0.4627017628713182 0.6727242155918308 0.5011227588654601 1.0 0.7038117625608237 8 Q8WXH0 1 +Cerebral cortex radially oriented cell migration 0.4627017628713182 0.6727242155918308 0.5011227588654601 1.0 0.7038117625608237 8 Q8WXH0 1 +Import into cell 0.3629528344326571 0.6721664250974869 0.5014777528056851 1.0 0.7041560559659237 29 P41440,P30825,P23634,P31751 4 +Positive regulation of cell growth 0.3580104979884135 0.6709855548361414 0.5022297318188658 1.0 0.7047488136950372 32 Q96K76 1 +Membrane protein proteolysis 0.4572488854449812 0.6691995358934268 0.5033682022712433 1.0 0.7058683238632403 9 Q9NZ08,O43847,P38159 3 +Positive regulation of ruffle assembly 0.3886731391585806 0.6690370884869669 0.5034718194657011 1.0 0.7058683238632403 3 P07737,Q7L576 2 +Response to wounding 0.3136747066208756 0.6672820415168449 0.5045919952175844 1.0 0.7068050824137023 73 P07948,P42785,Q92766,Q16625,P09601,P46108,Q8WTV0,Q96AY3,P38435,Q96G23 10 +Hindbrain development 0.3555969766473092 0.6666911723773543 0.5049694186209326 1.0 0.7070454288685404 33 P54802,P46108,O95456,Q9BRK5,Q5KU26 5 +Isoprenoid metabolic process 0.3682034840817418 0.6663119094998019 0.5052117548322548 1.0 0.7072302573650913 23 Q9HB40,O43464,P48449,P14324,Q9BTZ2,O60762 6 +Regulation of mitotic recombination 0.3877022653721721 0.6639861373921261 0.5066991836195787 1.0 0.708538779886889 3 Q92878,P49959 2 +Regulation of cysteine type endopeptidase activity 0.3228318054808791 0.6622249866621768 0.5078270430207836 1.0 0.709659057976169 50 Q9P0J0,P23396,O43464,Q96F07,P51572,Q15392,Q15375,Q13794,O95831,Q9Y3D6,Q96K76,P78318 12 +Cell cell signaling 0.2874922738528733 0.6593886129247197 0.5096462524524021 1.0 0.711108506360448 165 Q13614,Q9NWU2,Q4J6C6,Q9BZK7,Q9Y4G8,P50897,Q96K76,Q13641,P41440,Q9NR77,Q13555,Q13432,Q9UQB8,O95563,Q9UIQ6,Q6WKZ4,P05771,Q8N163,P50416,Q9UBB6,P51790 21 +Establishment of lymphocyte polarity 0.3867313915857666 0.6589424445191706 0.5099327286684603 1.0 0.7113533821033364 3 Q14160,P35579 2 +Liver morphogenesis 0.3864077669902945 0.657262847060508 0.5110119212925595 1.0 0.7122388378963483 3 Q15648,Q15418 2 +Negative regulation of cell cycle phase transition 0.3112246903104127 0.6559539716316881 0.511853740187 1.0 0.7129470827028835 56 Q68E01,Q9UNS1,Q8N163,Q9BXW9,P53350,Q13564,P14635,Q9Y619,P38398,Q96JB5,P06493,Q08J23,O60566,Q96K76,Q9NXR7 15 +Endosome to lysosome transport 0.4246706176510699 0.6552364279353062 0.5123155439053699 1.0 0.7134352892534046 13 Q9H267,P20645,Q6IQ22,Q96AX1 4 +Cellular response to vitamin 0.4666143916083034 0.6528777106315716 0.5138351195970559 1.0 0.7147749819047587 6 Q15648,Q13573,Q96C86,Q8TB36 4 +Lipid oxidation 0.3281455360543408 0.648682699757734 0.5165434888955913 1.0 0.7177833720582856 45 P49748,Q9BWD1,Q13011,P31751,P23786 5 +Development of secondary female sexual characteristics 0.3841423948220099 0.6455289907368964 0.5185844373860387 1.0 0.7199697898269997 3 Q15648,Q99623 2 +Cytokine production involved in immune response 0.4520016256405951 0.6444458843292596 0.5192863386302458 1.0 0.7206376771205618 9 P09601,P04439 2 +Negative regulation of cation channel activity 0.4383582655737857 0.6438241022421198 0.5196895026121928 1.0 0.7208850274278633 5 Q12955,P28161 2 +Regulation of respiratory burst 0.3555483662245184 0.6434946275601133 0.5199031996859644 1.0 0.7209028698347432 2 P63000 1 +Microtubule polymerization 0.3639109536946554 0.6418507006272008 0.5209701264744568 1.0 0.7218803525078401 24 Q96S59,P23396,Q16625,Q9BSJ2,Q14203,Q7Z460,P36405,Q96P70,P36404,Q13526 10 +Regulation of hormone metabolic process 0.4374999999999982 0.6398509285193416 0.5222695190346629 1.0 0.72352444716062 5 P16435,O75844,Q9UNE7,O60678 4 +Central nervous system development 0.2858720502158525 0.637762822401256 0.5236280839309868 1.0 0.725093112550794 174 Q9H6E4,P46379,O94813,Q9Y4G8,P50897,Q15102,Q9UQB8,P23634,O14773,P80723,Q8WXH0,O95817,Q5KU26,P54802,P08670,Q86XL3,O43464,O94901,O75503,Q15375,Q06481,Q96JB5,Q9NQZ2,Q9BRK5,P07948,Q9BXW9,O75787,P46108,Q05086,O95456,Q9UKA9,P07196 32 +Motor neuron apoptotic process 0.3542542866386214 0.6363712074979371 0.5245345028311066 1.0 0.725877841784843 2 O75312 1 +Regulation of type i interferon mediated signaling pathway 0.4501319405128674 0.6356670601060839 0.5249934504866947 1.0 0.7263561445326382 9 Q14166,Q7Z434,Q9Y3Z3,Q9NZI8 4 +Galactose catabolic process 0.3539307667421513 0.6345928701336034 0.5256939794593807 1.0 0.7265427465393536 2 P16278 1 +Galactose metabolic process 0.3539307667421513 0.6345928701336034 0.5256939794593807 1.0 0.7265427465393536 2 P16278 1 +Response to catecholamine 0.4369919483536857 0.6328552158935782 0.5268281953381571 1.0 0.7270721633643523 11 P23634 1 +Head morphogenesis 0.4358437124419237 0.6321971089665387 0.5272580862076812 1.0 0.7274481990080148 5 O95470 1 +Regulation of rna binding 0.4492471490874844 0.631520524456835 0.5277002335656271 1.0 0.727744943450015 9 Q9H1E3,Q86X55 2 +Post translational protein modification 0.4365787178975935 0.6308201367985611 0.5281581353063609 1.0 0.7278964355009256 11 Q32P28,O60725 2 +Cell morphogenesis involved in differentiation 0.2988328990435142 0.6306577827366523 0.5282643085725907 1.0 0.7278964355009256 107 Q9Y4F1,O94813,Q13641,Q92766,P50570,P41440,P46108,Q96AX1,Q05086,Q8N0X7,Q06481,Q96PU5,Q9Y4G8,Q9UQB8,P42892,P84095,P07196 17 +Synapse assembly 0.3946406332338447 0.6275073984955943 0.5303266879859163 1.0 0.7302136394805465 17 Q15375,Q9Y4F1,Q13641 3 +Response to epidermal growth factor 0.427829943377627 0.6273929771103303 0.5304016701125467 1.0 0.7302136394805465 12 Q9UQB8 1 +Regulation of production of molecular mediator of immune response 0.3615474133150333 0.6258716787511154 0.5313991120953931 1.0 0.7312727154425654 24 Q9NQT5,Q7Z434,P09601,O96028,P02786,P04439 6 +Regulation of axonogenesis 0.3943199349723966 0.6256530456639112 0.53154253738978 1.0 0.7313130853549022 17 Q8N0X7,O94813,P07196 3 +Positive regulation of cell population proliferation 0.2933017543349287 0.6226513374926215 0.5335136673380372 1.0 0.732868037455176 113 Q96HY6,P07948,P30825,Q92766,Q9Y3Y2,Q08722,Q9NWU2,P31751,P60602,P09601,Q9HCL2,P43307,Q9H2J4,P14635,P02786,P04899,P84095,P49366 18 +Glial cell migration 0.4268154732079151 0.6222584575029098 0.5337719327511801 1.0 0.732868037455176 12 Q8WXH0,Q96G23 2 +Calcium mediated signaling 0.3989915176718888 0.620561985332334 0.5348878582932834 1.0 0.7341822637387466 16 P51572,Q9Y3D6,P23634,P28161 4 +Regulation of leukocyte differentiation 0.3612837925009267 0.6167160472031822 0.5374220347387317 1.0 0.7363991540562783 22 P07948,Q9BXW9,P12956 3 +Negative regulation of mrna processing 0.3606964316702906 0.6160305561320201 0.5378743530160246 1.0 0.7367039749642559 23 P18615,Q5VTR2,P61978,O75494,O00422,Q16629,P98175,P22626,Q15287,Q08170,Q13247,P38159 12 +Autophagosome organization 0.3611190166550895 0.615631087188627 0.538138028960538 1.0 0.736778522215066 22 O75396,P60520,Q8TBX8,O95817 4 +Positive regulation of protein localization to cell cortex 0.4069278083522104 0.6155998281305393 0.5381586647442962 1.0 0.736778522215066 4 P11171,P63096,O43491 3 +Positive regulation of developmental process 0.284479974645277 0.6148025072731249 0.5386851532878711 1.0 0.7373093888908967 175 Q8WUJ1,O94813,P12956,Q9HCL2,Q9NZ08,Q9Y4G8,Q9NQT5,P04114,P02786,Q9Y3D6,Q13641,P41440,Q96PU5,Q9UQB8,P80723,P16989,P50570,P09601,P05771,P07948,Q92766,P46108,O43290,Q9H2J4,Q86X55,P07196 26 +Regulation of chromatin assembly 0.4030705208104677 0.6140952380787513 0.5391523947974268 1.0 0.7373515789740784 15 Q15047 1 +Regulation of chromatin assembly or disassembly 0.4030705208104677 0.6140952380787513 0.5391523947974268 1.0 0.7373515789740784 15 Q15047 1 +Positive regulation of autophagy 0.3596638889484965 0.6131837334495593 0.5397548592051411 1.0 0.7378606627223192 24 Q8TBX8,P09601,O95817 3 +Positive regulation of phagocytosis 0.4494191626221872 0.6116345480782971 0.5407795750328166 1.0 0.7383081290001332 8 Q06481,P50570,Q08722 3 +Centromeric sister chromatid cohesion 0.4313471502590654 0.6115119088220854 0.5408607368504039 1.0 0.7383081290001332 5 P35222,O60566,Q9GZZ1,P30153 4 +Regulation of entry of bacterium into host cell 0.4056328909031919 0.6093666730771731 0.5422814229360267 1.0 0.7389506634821281 4 Q96KP1,Q9BTY2,P06756 3 +Entry of bacterium into host cell 0.4056328909031919 0.6093666730771731 0.5422814229360267 1.0 0.7389506634821281 4 Q96KP1,Q9BTY2,P06756 3 +Cellular response to carbohydrate stimulus 0.358950895899094 0.6083917971234989 0.5429276506220773 1.0 0.7393597281681571 24 O95563,Q96RR1,Q5KU26 3 +Negative regulation of double strand break repair via nonhomologous end joining 0.3490779682950479 0.6080432214981333 0.543158808188563 1.0 0.7395174087699 2 Q9UBB9 1 +Synapse organization 0.3028157766140724 0.6063115577344056 0.5443078852176617 1.0 0.7405956049248288 59 Q13614,O95793,Q9Y4F1,Q13641,P07437,Q15375,Q05086,Q9UQB8,Q9BRK5,P07196 10 +Positive regulation of histone deacetylation 0.4522000141951695 0.6058054593041355 0.5446439440898039 1.0 0.7405956049248288 7 O43823,Q9ULX6 2 +Positive regulation of protein deacetylation 0.4522000141951695 0.6058054593041355 0.5446439440898039 1.0 0.7405956049248288 7 O43823,Q9ULX6 2 +Phosphatidylinositol 3 kinase signaling 0.4478638174329067 0.6045552637167514 0.545474539046308 1.0 0.7414104739793966 8 Q05086,Q10713 2 +Positive regulation of cellular response to insulin stimulus 0.4040017232036971 0.6015340696802497 0.5474843267569554 1.0 0.7433540636543282 4 P04899 1 +Protein localization to extracellular region 0.3022987693189268 0.6008805878597063 0.547919523505346 1.0 0.7435057350257623 59 Q32P28,O95563,Q13555,Q6IQ22,Q6WKZ4,Q16850,P53367 7 +Regulation of nadp metabolic process 0.4286602319919672 0.5992196448829762 0.5490264242654141 1.0 0.7441868004950951 5 P48163,Q9NQ88 2 +Long chain fatty acid biosynthetic process 0.3747945312267364 0.5975711565404231 0.5501261147458978 1.0 0.745204648250466 3 P28161 1 +Positive regulation of cell differentiation 0.2977008019595011 0.5953323602606604 0.5516213289980989 1.0 0.7469143892855542 105 Q8WUJ1,P07948,O94813,Q92766,P50570,P12956,P46108,O43290,Q9Y4G8,Q9UQB8,P04114,Q86X55 12 +Cellular macromolecule localization 0.2626733665920617 0.5924996270973263 0.5535160703791735 1.0 0.748177352593821 514 P46379,Q8NBM4,O60830,P29372,Q4J6C6,Q99595,P36405,P50402,P55786,Q96DY7,P40616,Q15388,Q8N4H5,Q13641,Q9UI26,P55196,P41440,Q9BXS5,Q16625,Q8WWC4,P60602,Q96PU5,O95831,Q9BRK0,Q9Y584,P53367,P31751,O60725,P62072,Q96RT1,O43731,Q9HD20,O15118,Q8NEY8,Q9Y4G8,Q5BJH7,P67809,P24390,Q6IQ22,P23634,O14773,Q96HY6,Q96RL7,Q9BZG1,Q9Y282,Q10713,Q9P0J0,O95429,Q16181,Q9NS69,Q14108,P02786,P84095,P43307,P35241,O95817,O43464,Q9UFC0,Q06481,P27105,P83436,P60520,P51572,P20645,O15400,P57740,Q9NPA0,Q9H267,Q96P70,Q5JRX3,Q9Y5K8,Q9Y3D6,O00459,Q9Y2D4,Q96AX1,O43681,Q13190,Q92974,Q6IAA8,O75381,O94901,Q9P2W9,Q99567,Q96JB5,Q92643,Q13561,O95071,O15504,Q96FF9,Q9NRW7,Q9Y2T2,O60499 92 +Regulation of defense response 0.3074065437497885 0.5923674577765973 0.5536045527851003 1.0 0.748177352593821 77 P07948,Q96J02,P60900,Q92879,Q9BXW9,O75844,Q08722,Q14166,P12956,P46108,P28070,Q9NZ08,Q9Y3Z3,Q06481,P04439,P33527 16 +Regulation of cell population proliferation 0.2782101827868036 0.5918569530485303 0.5539463816126766 1.0 0.7484815147844134 213 Q32P28,Q9NWU2,P12956,Q9HCL2,Q9Y4G8,Q96DY7,P02786,P84095,P49366,Q13641,Q9NR77,P60602,Q15392,Q99627,P43307,P04899,Q9Y3Y2,Q96HY6,Q9UNS1,Q96J02,Q92879,Q08722,P09601,Q06481,P14635,P07948,P30825,Q92766,Q71SY5,P31751,Q9UKA9,Q9H2J4,Q96G23 33 +Amino acid import 0.4449532716069462 0.591352953852249 0.5542839557334789 1.0 0.748622030394353 8 P30825 1 +Cardiac septum morphogenesis 0.4268506481979189 0.5909710117351107 0.5545398441482767 1.0 0.7486835291007921 5 O94813 1 +Negative regulation of cytoskeleton organization 0.3350878481831549 0.5906169617625001 0.554777097353027 1.0 0.7488147386887563 38 O94813,Q13045,P29372,P28289,Q9UEY8,P35241,P38398,Q92974,P35611 9 +Regulation of wnt signaling pathway 0.3233311119362385 0.5883227694984438 0.5563156651318029 1.0 0.7502595021028522 43 Q8N163,O95071,O75787,Q13641,Q8NBM4,Q9NWU2,Q9BZK7,Q96K76 8 +Appendage morphogenesis 0.411747200696053 0.5878725310380575 0.5566178553174872 1.0 0.7502994539723128 13 P42892 1 +Regulation of macroautophagy 0.3176718433586788 0.5870251203308748 0.5571868357474568 1.0 0.7502994539723128 48 P09601,P21796,O75396,O15118,Q9Y487,Q8TBX8,Q93050,Q9Y5K8,O95817 9 +Positive regulation of intracellular transport 0.3056271362299612 0.5865624044231168 0.5574976384945796 1.0 0.7502994539723128 69 Q13614,Q99653,P50402,O75312,P55786,P15311,Q9Y3D6,O00459,Q12955,O00410,Q7Z434,Q9NW64,P35241,O95817,Q99496,O43464,Q9P2W9,P27105,O95071,P31751,P51572,Q9Y282,P52298,Q07666,P06493 25 +Sprouting angiogenesis 0.4197124595834381 0.5865353649407035 0.5575158033182723 1.0 0.7502994539723128 12 P09601 1 +Pre mirna processing 0.3445486897444176 0.583487573538134 0.5595651199377198 1.0 0.7517946801091562 2 O75569 1 +Mirna loading onto risc involved in gene silencing by mirna 0.3445486897444176 0.583487573538134 0.5595651199377198 1.0 0.7517946801091562 2 O75569 1 +Appendage development 0.392035315454325 0.5815950979024695 0.5608394456389716 1.0 0.7530332732605378 16 P42892 1 +Fat cell differentiation 0.3553855098437719 0.5808529756303278 0.5613395475794243 1.0 0.7532100222322384 23 Q92766,P31751,Q9BZK7,Q9NZ08,Q9BRK5,Q86X55,Q8N4Q0 7 +Positive regulation of mirna mediated gene silencing by inhibition of translation 0.3711974110032401 0.5793308357182719 0.5623659628945896 1.0 0.7539773733851327 3 P40763,Q04637 2 +Regulation of cation transmembrane transport 0.3203392360954688 0.5791369827495741 0.5624967476212976 1.0 0.7539950130180924 45 P07948,Q99653,Q13586,Q4KMQ2,P50570,P46939,Q12955,P21796,P54652,Q06787,Q96PU5,P27105,P23634,P28161 14 +Positive regulation of protein serine threonine kinase activity 0.3554348542630781 0.5784051011691427 0.5629906507481728 1.0 0.7543957498032539 22 Q9NQS7,P23396,P18031,Q9Y4R8,Q9Y4G8,P23634,Q8NDZ4,P14635,P30040,P41240 10 +Regulation of spontaneous synaptic transmission 0.3432546101585191 0.576513773487664 0.5642679627950669 1.0 0.7557370751183407 2 P55011 1 +Spontaneous synaptic transmission 0.3432546101585191 0.576513773487664 0.5642679627950669 1.0 0.7557370751183407 2 P55011 1 +Regulation of dna templated transcription elongation 0.3517509036145109 0.5761733537063956 0.5644980140655731 1.0 0.7558872509213126 27 Q8N163,P35269,O14776,Q8IXH7 4 +Second messenger mediated signaling 0.3544004945409647 0.5743679642477182 0.5657188266941953 1.0 0.7569481639939702 23 P51572,Q9Y4G8,P23634,Q9Y3D6,P28161 5 +Sensory perception of light stimulus 0.4005457205760609 0.5743031758216806 0.5657626604828567 1.0 0.7569481639939702 14 Q6P4Q7,O60313,Q9H6K4,Q13432,O75695,Q96DA6,P50897 7 +Regulation of steroid metabolic process 0.3956523161284098 0.5735962094693575 0.5662410774082238 1.0 0.7572721273078896 15 P49748,P04114 2 +Rac protein signal transduction 0.4316518999002668 0.5711718346428145 0.567883168418551 1.0 0.7583013711914552 10 P84095,P50570 2 +Neuron projection regeneration 0.4478750917668879 0.5708882743759826 0.5680753797911651 1.0 0.7583013711914552 6 Q99707,Q96G23,P07196 3 +Organ growth 0.3663052970595647 0.564836024607892 0.5721853014543727 1.0 0.7628343973216575 20 Q05086,P16989,Q99956 3 +Neuron projection organization 0.3661727915921122 0.5640237572611032 0.572737964010039 1.0 0.7634124244758473 20 Q05086,Q9UQB8 2 +Cellular hyperosmotic response 0.438145863039146 0.5607168429561665 0.5749905833247786 1.0 0.7653020150664901 8 Q9BUP0,P16989 2 +Natural killer cell mediated immunity 0.4339528026680523 0.5607157296965143 0.5749913423650883 1.0 0.7653020150664901 9 P07437,P46108,P04439 3 +Regulation of neutrophil chemotaxis 0.4415551590492946 0.5587743172876863 0.5763157523261073 1.0 0.7667463620610934 7 O94813,Q00013 2 +Regulation of cell adhesion 0.3033302351877133 0.5578290340810527 0.5769611345996202 1.0 0.7674457092308706 86 O95429,Q9HCL2,P02786,P49366,P23396,P41440,Q53GQ0,Q8WWI1,P35241,Q96J02,P50570,Q08722,Q15375,P07948,P30825,Q92766,P46939,P46108,O43290 19 +Response to growth hormone 0.3947044348337531 0.5573214726032807 0.5773078074012898 1.0 0.7676346844438046 4 P07948,P40763 2 +Negative regulation of calcium ion transmembrane transport 0.4447089028334007 0.557270370154244 0.5773427166464247 1.0 0.7676346844438046 6 P21796,P28161 2 +Meiotic cell cycle process 0.337048823718508 0.5547838447466185 0.5790425185460228 1.0 0.769097087418153 35 Q92791,P46379,Q9BXW9,P53350,O94901,P35579,Q96KQ7,Q08J23,Q9NTJ3 9 +Response to arsenite ion 0.3390488515043658 0.5539851962684598 0.5795889770790439 1.0 0.769185371237406 2 Q9H2U1 1 +Regulation of cell cycle checkpoint 0.4323286318455211 0.5533016835929424 0.580056848401256 1.0 0.7696469464400851 9 P14635 1 +Polyol catabolic process 0.4429931266021876 0.5499220689395613 0.5823728266787713 1.0 0.7714424093843613 6 Q13614 1 +Rna interference 0.4311441354660265 0.54790843421501 0.5837547772551348 1.0 0.7722559948806734 9 Q92879,Q5KU26 2 +Regulation of intracellular signal transduction 0.2660829707926706 0.5473750565163186 0.5841210882552101 1.0 0.7722559948806734 249 O94813,Q9P0J0,Q9HBM6,O95429,Q99956,P61978,Q9Y4G8,P02786,Q9Y3D6,Q96K76,O00459,Q13641,P23396,P41440,Q9UMX5,P45880,P35241,P23634,P04899,Q92974,Q96J02,P16989,Q6IAA8,P50570,O43464,P09601,Q15375,Q9NWT1,Q13794,Q96EE3,Q96JB5,P14635,P05771,P07948,Q8N163,O75844,P51572,P46108,Q05086,Q10713,Q96P70,Q96RT1,P78318 43 +Embryo development ending in birth or egg hatching 0.2790845689614333 0.5471664999812006 0.5842643489698882 1.0 0.7722559948806734 132 P16989,Q9H0G5,Q9NR56,Q08J23,P67809,Q9Y5P4,P14635,O43819,Q9BZK7,P23786,O43772,Q9BRT9,P04114,Q96AY3,P42892,Q9Y3Y2 16 +Pyroptosis 0.3377547719184676 0.5470967598166938 0.5843122582170461 1.0 0.7722559948806734 2 Q9NZI8 1 +Regulation of cilium assembly 0.4034387024744039 0.5453311734270796 0.5855257677171541 1.0 0.7735408431712609 13 Q66K14,P50570,Q16181 3 +Cellular response to heat 0.3485988594304317 0.5395587916000797 0.5895013418686892 1.0 0.7773510803082283 24 O43464,P09601,O95817 3 +Regulation of response to wounding 0.3736985842905837 0.5393775595765257 0.5896263618779494 1.0 0.7773560221385553 18 P46108,Q16625,Q92766,Q96G23 4 +Cell cycle checkpoint signaling 0.3122216394221617 0.5373297315816772 0.5910398717979528 1.0 0.7788991731547856 48 Q68E01,Q9UNS1,Q8N163,Q9BXW9,P53350,Q13564,P14635,Q9Y619,P38398,Q96JB5,P06493,Q08J23,O60566,Q9NXR7 14 +Regulation of necrotic cell death 0.4241059331361235 0.5360017512154506 0.591957340146192 1.0 0.7796273988775613 10 P16989,Q92974 2 +Response to molecule of bacterial origin 0.3358074854407932 0.5313297763309833 0.5951902748214999 1.0 0.7819572989558955 34 P07948,P08670,Q86U42,O43823,Q8WTV0,P04114,Q96RT1 7 +Negative regulation of cellular response to insulin stimulus 0.4351136002956817 0.5307305734133605 0.5956054964468573 1.0 0.7822092831749069 7 Q8TBX8,Q06481,P05771 3 +Mitochondrial fusion 0.3920694359789843 0.529722916725708 0.5963040565488185 1.0 0.7829391647844994 14 Q9UJZ1,P02786,Q9NX63 3 +Positive regulation of cell death 0.2908698016987502 0.5290584900127019 0.5967648758334572 1.0 0.7830630202850483 108 O94813,Q9BUP3,Q9NS69,Q99956,P11717,Q9Y4G8,Q9Y3D6,P17655,P23396,O95831,Q92879,P50570,Q4KMQ2,O43464,P09601,Q15375,Q13794,Q9NQX7,P07948,Q8N163,P51572 21 +Peptidyl arginine methylation 0.3884309293185447 0.5279375849466302 0.5975426570364035 1.0 0.7832209011437835 4 Q86X55 1 +Peptidyl arginine n methylation 0.3884309293185447 0.5279375849466302 0.5975426570364035 1.0 0.7832209011437835 4 Q86X55 1 +Regulation of alternative mrna splicing via spliceosome 0.3386377916407502 0.5278285789631861 0.5976183194218792 1.0 0.7832209011437835 32 Q8IY67,O95319,Q9H0G5,Q92879,Q9NR56,O75525,Q06787,P51114,P62995,P98175,Q9Y5S9,Q07666,Q13247,P38159 14 +Cell growth 0.2978668726011926 0.5272316091499647 0.5980327606540872 1.0 0.7835545113866816 94 Q8N163,Q96J02,O94813,Q9P0J0,Q9HBM6,P50570,Q6IAA8,Q96F07,Q96PU5,P50897,Q8N0X7,P02786,Q5BJF2,Q96K76,Q9BTE7 15 +Nuclear transcribed mrna poly a tail shortening 0.4125294804744747 0.5266163830385518 0.5984600126733639 1.0 0.7837821623361061 5 P11940 1 +Regulation of cell cycle g2 m phase transition 0.3312875921472163 0.5259417833062375 0.598928656628559 1.0 0.7838163921986654 36 Q68E01,P53350,Q13564,Q9Y619,P38398,Q96JB5,P06493,P14635,Q96K76,Q9NXR7 10 +Fluid transport 0.3335490132643121 0.5248576283667483 0.5996821666300423 1.0 0.7843972441014211 2 O43865 1 +Positive regulation of developmental growth 0.365527546467567 0.5244230173807201 0.5999843506753928 1.0 0.7843972441014211 19 Q9HCL2,Q96PU5,P16989 3 +Positive regulation of growth 0.3149432641840891 0.5234862724413223 0.6006359015104454 1.0 0.7850889332548848 44 Q9HCL2,Q96PU5,P16989,Q96K76 4 +T cell apoptotic process 0.4141496591764719 0.5223936071229667 0.6013963061846082 1.0 0.7857073808504196 11 Q9HCL2 1 +Nuclear transcribed mrna catabolic process deadenylation dependent decay 0.3459493945309294 0.5221855768617201 0.6015411272564268 1.0 0.7857073808504196 24 P67809,Q969T7,Q96B26,Q9NQT5,O60506 5 +Regulation of fatty acid metabolic process 0.3906056405017116 0.5221019502102755 0.6015993487073104 1.0 0.7857073808504196 14 P49748,P50416,P31751,Q15118 4 +Response to carbohydrate 0.3307272251504968 0.5216457105777708 0.6019170306414021 1.0 0.7857427890481119 36 P07948,O95563,Q9HCL2,Q99808,Q96RR1,P04114,P05771,Q5KU26 8 +Neural retina development 0.4329726203548518 0.5214849214084599 0.6020290069654581 1.0 0.7857427890481119 7 P23634 1 +Trophectodermal cell differentiation 0.3865328585302605 0.5191244802759417 0.6036739380826928 1.0 0.7874542008770983 4 Q6PD62,Q13895,A5YKK6 3 +Cellular response to interferon beta 0.4322415185351308 0.518336641449967 0.6042234120867893 1.0 0.7878502993239055 7 O43464,Q9P0J0 2 +Response to interferon beta 0.4322415185351308 0.518336641449967 0.6042234120867893 1.0 0.7878502993239055 7 O43464,Q9P0J0 2 +Regulation of response to dna damage stimulus 0.2999628886403269 0.5180197619774316 0.6044444812943075 1.0 0.787978264205107 71 Q9UNS1,Q8N163,O95071,Q9HBM6,O75844,P23396,P61978,Q96S55,Q9NQ88,P51114,P38398,Q13794,Q9NY27,O96028,P18887,Q96K76,Q9NXR7 17 +Lymphocyte activation involved in immune response 0.3450113965585741 0.5160608121185181 0.6058119368363262 1.0 0.7893962207152596 24 Q9NQT5,P02786,Q9UQ84 3 +Positive regulation of nervous system development 0.3336102650264239 0.514976383930232 0.6065695227971435 1.0 0.7896244194008306 34 Q13641,Q9UQB8 2 +Regulation of b cell proliferation 0.4340055761491632 0.5118108643775056 0.6087833859689491 1.0 0.7920238490077053 6 P02786 1 +Artery development 0.4270478408498525 0.5115686539795683 0.6089529282263801 1.0 0.792083658671083 8 Q96AY3 1 +Positive regulation of nucleocytoplasmic transport 0.3429838039358786 0.5108718669824409 0.6094407818062466 1.0 0.7923966351679596 26 O00459,Q16630,O95071,Q92688,Q7Z434,O00410,Q9NW64,P50402,O75312,P52298,Q07666,P06493,O95817 13 +Retina morphogenesis in camera type eye 0.3844929866261569 0.5096946888456724 0.610265374480923 1.0 0.7930708980107477 4 P54802 1 +Regulation of inflammatory response 0.334539150208442 0.5094251367770665 0.6104542606528907 1.0 0.7930708980107477 33 P07948,Q92879,Q9BXW9,Q08722,P28070,P33527 6 +Development of secondary sexual characteristics 0.3842667529944878 0.5086515805563968 0.610996467168748 1.0 0.7934578073633087 4 Q15648,Q07812,Q99623 3 +Positive regulation of transport 0.2785626410908651 0.5086470448745429 0.6109996469805448 1.0 0.7934578073633087 165 Q13614,P61978,P55786,P50897,Q03164,Q9Y3D6,O00459,P41440,Q16625,Q96PU5,P35241,P04899,O95817,P50570,Q08722,O95563,O43464,Q4KMQ2,Q06481,Q9P2W9,P27105,P35580,P08183,P28161,P31751,P51572,Q9Y282,P52298 28 +Alpha linolenic acid metabolic process 0.3841864775668729 0.5082815814420701 0.6112558850293566 1.0 0.7936297798335378 4 O14734 1 +Primary alcohol metabolic process 0.3442784783211757 0.5066099361819555 0.6124285351982877 1.0 0.7948296330281241 22 P30837 1 +Regulation of organ growth 0.4218717734277086 0.5061119505230454 0.6127780616406273 1.0 0.7948483232487409 9 P16989,Q99956 2 +Negative regulation of defense response to virus 0.4077871173169007 0.5057019597819359 0.6130658922932009 1.0 0.7948483232487409 5 Q96J02 1 +Regulation of cellular component size 0.299674858447482 0.5047260099639062 0.6137512899575264 1.0 0.7951004375771625 76 P07196,O94813,Q13045,O95429,Q4KMQ2,P50570,Q96F07,P51790,P28289,Q15375,P62993,Q9UEY8,O96011,P35241,Q9UQB8,Q9P2J5,Q8N0X7,P35611 18 +Positive regulation of reactive oxygen species metabolic process 0.3952903494955337 0.504283672412568 0.614062049474366 1.0 0.7953400155851054 13 Q9BTZ2,P60602,P51790 3 +Cellular response to molecule of bacterial origin 0.3434191790050775 0.5030020875848527 0.6149628044366642 1.0 0.7963457730179834 23 P07948,P08670,Q86U42,O43823,Q8WTV0 5 +Regulation of protein localization to cell cortex 0.4070595854922259 0.5025123581872575 0.6153071615420789 1.0 0.7966307625701323 5 P11171,P63096,O43491,P53350 4 +Histone h4 k16 acetylation 0.4248395669258542 0.5019173541541723 0.6157256573777454 1.0 0.7970116041581883 8 O75844,Q03164,Q12824 3 +Secretion 0.2771905624607185 0.5004495750109842 0.6167585534929909 1.0 0.7977042630932348 142 Q96FZ7,Q96PC5,Q32P28,Q4J6C6,P50897,Q9Y2D4,Q13505,Q16836,Q13555,Q6IQ22,P04899,P30040,Q9NVJ2,O95563,P09601,P00403,Q6WKZ4,Q9Y2G5,Q99808,Q9BRK5,P53367,P05771,P35580,O15126,P07948,Q15758,P35670,O43760,Q8N183,P50416,P20645,P35579,Q16850 33 +Cellular response to vitamin d 0.4061681837020611 0.4986113598104102 0.6180532007879334 1.0 0.7988951435875484 5 Q15648,Q13573,Q8TB36 3 +Peptidyl proline modification 0.339395753632392 0.498203067270268 0.6183409207618973 1.0 0.7991059076781777 28 Q32P28,O75718,Q9NWM8,O95302,Q96AY3 5 +Regulation of leukocyte mediated cytotoxicity 0.4272858484634919 0.4971200246505529 0.6191044143320128 1.0 0.7997927783941643 7 O15400,P46108,P04439 3 +Negative regulation of calcium ion transport 0.42373233631918 0.4970951417403252 0.6191219604355449 1.0 0.7997927783941643 8 Q06787,P21796,P28161 3 +Regulation of immune effector process 0.3184587941329536 0.4957188994129586 0.6200927509819261 1.0 0.8005106727710284 40 P07948,Q08722,Q7Z434,P09601,P46108,O15400,Q06481,O96028,Q9NQT5,Q9NUQ9,P02786,P04439 12 +Cytoplasmic pattern recognition receptor signaling pathway 0.4012071250307786 0.4955991916463295 0.6201772232419542 1.0 0.8005106727710284 12 Q96RT1 1 +Cell surface receptor signaling pathway involved in cell cell signaling 0.297461593997273 0.493764193475913 0.6214727236517827 1.0 0.8013760125946344 70 Q13614,Q9GZS3,Q8N163,O95071,Q13641,Q8NBM4,O75787,Q9NWU2,Q9BZK7,P50402,Q99808,Q9UQB8,Q96K76 13 +Positive regulation of cysteine type endopeptidase activity 0.3373180223087192 0.4909844237914233 0.6234374642990952 1.0 0.8032149267489417 29 Q9P0J0,P23396,O43464,Q96F07,P51572,Q13794,O95831,Q9Y3D6 8 +Antigen processing and presentation of exogenous antigen 0.4221900681825163 0.4903974929231326 0.6238526504058912 1.0 0.8033136780035682 8 Q03518,Q9UIQ6,P50570 3 +Exocytosis 0.2970720573198739 0.4895225362436559 0.6244718035149428 1.0 0.8037162606138054 70 O43760,P09601,Q6IQ22,Q6WKZ4,Q4J6C6,P05771,Q9BRK5,P04899,O15126 9 +Positive regulation of isotype switching 0.4219654988216078 0.4894241388021182 0.6245414499403066 1.0 0.8037162606138054 8 P02786,O96028,Q9NQT5 3 +Regulation of proteolysis 0.2770128962018763 0.4850694202409971 0.6276271029782476 1.0 0.8068051001069799 155 P46379,Q9P0J0,Q9UL46,O43847,Q9Y3D6,Q96K76,Q92896,Q9Y5A7,P23396,Q15392,O95831,Q92530,Q96HY6,Q96J02,O43464,Q96F07,Q15375,Q06481,Q13794,Q96JB5,P07948,Q8N163,Q96A26,P60520,P51572,Q05086,Q9H2J4,P78318 28 +Regulation of stem cell differentiation 0.3913214016562223 0.4845557664449683 0.6279914972711198 1.0 0.8068051001069799 13 Q08J23,Q9NX40 2 +Membrane lipid metabolic process 0.3170627235617793 0.4844388038479248 0.6280744851066817 1.0 0.8068051001069799 40 Q9Y2B2,O43464,Q9Y5P4,Q8NCC3,Q8NBX0,O95470,P50897,Q96G23,O60762 9 +Regulation of synaptic vesicle recycling 0.3787633538361864 0.4834489739631289 0.6287769819214868 1.0 0.8075456730348087 4 Q96CW1,Q7L576,Q00535 3 +Positive regulation of small molecule metabolic process 0.3787003500250609 0.483239954306902 0.6289253692599746 1.0 0.8075744424992862 15 P31751,Q13794 2 +Skeletal system morphogenesis 0.3737065705054163 0.4814363375042323 0.6302064159669052 1.0 0.8087242892621548 16 O95470,Q92896 2 +Positive regulation of interferon gamma production 0.4020263726751714 0.4805896730877652 0.6308081564627768 1.0 0.8087242892621548 5 Q9NUQ9,P04439 2 +Protein deneddylation 0.4195516290490444 0.4789924879462179 0.6319439727842828 1.0 0.8095045694538875 8 Q99627 1 +Somatic diversification of immune receptors 0.3391784319226746 0.4782957415554534 0.6324397268773687 1.0 0.8095910184888226 24 Q9NQT5,P02786,O96028,Q9UQ84 4 +Glycosylation 0.3001180811310017 0.4764925422610839 0.6337235191777679 1.0 0.8108119277304376 52 O60476,Q86YN1,O60502,O75503,Q9NR45,O15118,Q9HC07,Q9Y2V7,O60762 9 +Positive regulation of catalytic activity 0.27623824364169 0.4742216106920596 0.6353418842679941 1.0 0.8123960658603315 176 Q9P0J0,Q9UL46,Q86U42,P12956,Q9BRT9,Q9Y4G8,Q9Y3D6,P84095,Q16763,Q99627,Q13432,P23634,Q96M27,O95831,P04899,Q9BTE7,Q96HY6,Q9Y3Y2,O43464,Q96F07,Q13794,Q8WTV0,P14635,P07948,P31751,P51572,Q9BRX5,P46108,Q66K14 29 +Positive regulation of g0 to g1 transition 0.3235198964736306 0.4728140007834291 0.6363458844403651 1.0 0.8135175746435461 2 Q15648 1 +Polyadenylation dependent snorna 3 end processing 0.4241037624421879 0.4706250176686555 0.6379085388958874 1.0 0.8148652320292225 6 Q5RKV6,Q9NQT5 2 +Lipid storage 0.3716048952179403 0.4702192236150961 0.6381984011805972 1.0 0.8150730726375032 16 P50416,Q8WTV0,Q9H6V9 3 +Regulation of intracellular transport 0.2844526178666834 0.4700087490723719 0.6383487667975165 1.0 0.8151027082016097 111 Q13614,Q00765,Q8WU17,Q99653,Q8NBM4,O95429,Q6NUQ1,P50402,P55786,O75312,Q08J23,Q9Y3D6,O00459,Q7Z434,O00410,Q12955,P35241,O95817,Q99496,Q9BRK0,Q7Z3B4,O43464,Q9P2W9,P27105,Q93009,Q96DZ1,P53367,O95071,Q9Y385,P31751,P51572,Q9ULX6,Q9Y282,P52298,Q07666,P06493 36 +Negative regulation of mitotic cell cycle phase transition 0.3174552190540105 0.4686817502430672 0.6392971335153175 1.0 0.8159416710194073 39 Q68E01,P53350,Q13564,Q9Y619,P38398,Q96JB5,P06493,P14635,O60566,Q96K76,Q9NXR7 11 +Bone development 0.3502775001935213 0.4683257838593545 0.6395516325522896 1.0 0.8159416710194073 20 Q92896 1 +Regulation of isotype switching 0.4092459506309645 0.4682865993962687 0.6395796501729383 1.0 0.8159416710194073 10 P02786,O96028,Q9NQT5 3 +Regulation of innate immune response 0.3172256850577593 0.4668711748084638 0.6405920495379078 1.0 0.8162851450937461 39 P07948,Q14166,Q7Z434,P12956,P46108,Q06481,Q9NZ08,Q9Y3Z3,P04439 9 +Regulation of lymphocyte mediated immunity 0.3556249592861993 0.4668556947400042 0.6406031255445455 1.0 0.8162851450937461 19 P46108,O15400,O96028,Q9NQT5,Q9NUQ9,P02786,P04439 7 +Body fluid secretion 0.3793961712562346 0.4645818748025595 0.642230914613106 1.0 0.8176597928493666 14 Q15648,Q04656,P35670,Q9UNS2,Q13505,P07741,P00403,Q99808 8 +Muscle cell proliferation 0.3356513328765595 0.4624499810993218 0.6437586639614217 1.0 0.8176845082069326 26 P12956 1 +Positive regulation of supramolecular fiber organization 0.3164454975114126 0.460725784471152 0.6449953534996591 1.0 0.8187834564092871 39 P23396,O95429,Q08722,Q16625,P36405,Q9UQB8 6 +Myeloid leukocyte mediated immunity 0.3785176340546071 0.4601405697990058 0.6454153254909534 1.0 0.8190679541471018 14 P07948,P09601 2 +Negative regulation of t cell proliferation 0.421161604278469 0.4585631849339769 0.6465478789922123 1.0 0.8198559652502633 6 Q96J02 1 +Photoreceptor cell differentiation 0.3965032484754004 0.4568348971483605 0.6477897207199439 1.0 0.8212182559158753 5 P54802 1 +Positive regulation of protein catabolic process 0.2908641117551193 0.4562540070435914 0.6482073331528455 1.0 0.8214727175780427 63 Q96HY6,Q96J02,Q9P0J0,P46379,Q9Y5A7,P51572,Q96PU5,P35241,Q96JB5,O95816,Q13190,O43847 12 +Fucose metabolic process 0.3726612418602419 0.4559106640796846 0.6484542206948536 1.0 0.8215781034372455 4 Q9Y2G5 1 +Protein dephosphorylation 0.3018889089891146 0.4552777283496627 0.6489094469151935 1.0 0.8217126737902786 49 Q13614,Q8TF05,Q86XL3,Q99956,Q13555,Q9UNW1,Q6PIU2,P04899 8 +Protein k63 linked ubiquitination 0.3996739191172804 0.4549352946193938 0.6491557901497291 1.0 0.8217443880376903 11 Q96J02,Q16763 2 +Negative regulation of lipid biosynthetic process 0.4139211950278653 0.4548865129774863 0.6491908862750178 1.0 0.8217443880376903 8 P49748 1 +Plasma lipoprotein particle clearance 0.3774306315792913 0.4546596472648824 0.6493541158485452 1.0 0.8217887231173099 14 P09601,P61978,Q6PIU2,Q8WTV0 4 +Regulation of cell killing 0.4136994598774531 0.4539438670774337 0.6498692290608308 1.0 0.8222782783813513 8 O15400,P46108,P04439 3 +Low density lipoprotein particle clearance 0.3849932043310897 0.4534919303793054 0.6501945527965411 1.0 0.8225275475480223 13 P09601,P61978,Q6PIU2,Q8WTV0 4 +Regulation of actin filament based process 0.2946820729210843 0.4521833435588589 0.6511369065125545 1.0 0.823156264568297 74 O94813,Q13045,O95429,Q13576,Q08722,Q96F07,P46108,P28289,Q9NUL3,P62993,Q9UEY8,P35241,Q9UQB8,Q9NUQ9,P53367,P84095,P35611 17 +Regulation of extracellular matrix disassembly 0.3193141378194748 0.451441146825455 0.6516716332386316 1.0 0.823156264568297 2 Q7Z460 1 +Positive regulation of extracellular matrix disassembly 0.3193141378194748 0.451441146825455 0.6516716332386316 1.0 0.823156264568297 2 Q7Z460 1 +Negative regulation of lipoprotein particle clearance 0.3716413078666127 0.4513515867075122 0.6517361702846483 1.0 0.823156264568297 4 P01130,Q92945,P41240 3 +Cellular response to peptide 0.2907515313846768 0.4493334779104163 0.6531911109903179 1.0 0.8243660211553333 64 O00459,Q9UNS1,P07948,P08670,P31751,P46108,Q9HCD5,Q6IQ22,Q9H1E3,Q06481,P05771,Q9UQB8,Q8TBX8,P04899,Q92974,P33527 16 +Sterol biosynthetic process 0.3317177180312896 0.4465065763026902 0.655231363296007 1.0 0.8264527821187336 28 P48449,P14324,Q15392,Q16850,P04114,Q15800 6 +Postsynaptic modulation of chemical synaptic transmission 0.344012944983823 0.4461799567783922 0.6554672598662341 1.0 0.8265876717966871 3 P06730,Q7L576 2 +Phosphatidylinositol biosynthetic process 0.3463679539143315 0.4453785445402704 0.6560462147333184 1.0 0.8268297751554405 20 Q13614,O00459,Q9Y2B2,Q10713,Q8TBX8,O60762 6 +Regulation of cell junction assembly 0.328350555440614 0.4450756806634375 0.6562650629700391 1.0 0.8269430024843621 31 P41440,Q13641 2 +Cellular transition metal ion homeostasis 0.3341052247702696 0.4439957818054181 0.6570456336287722 1.0 0.8271332241331132 23 Q9Y487,P09601,O43819 3 +Tubulin complex assembly 0.3931347150259051 0.4425103359170012 0.6581199525779149 1.0 0.8274909564583041 5 Q9BTW9,P17987,O75347,Q15813 4 +Negative regulation of cell population proliferation 0.290720817813605 0.4399190049186654 0.6599957706549444 1.0 0.8289619204644745 95 P07948,Q96J02,Q92879,Q13641,Q32P28,Q9NR77,P09601,Q15392,Q99627,Q06481,Q9Y4G8,Q96DY7,Q96G23 13 +Regulation of leukocyte migration 0.3331537780643302 0.4399167595432933 0.6599973969711923 1.0 0.8289619204644745 24 P07948,O94813,Q4KMQ2,Q08722,P09601,P46108,P84095 7 +Regulation of mrna metabolic process 0.2738398199469177 0.4398911925196126 0.6600159151757228 1.0 0.8289619204644745 147 Q96C86,Q9HBH5,Q7L8L6,P61978,Q86U06,Q96B26,P62995,P98175,Q9NQT5,Q13247,Q99729,Q9H0G5,Q9NR56,Q9HCE1,Q15637,P67809,Q13573,O75525,Q6P6C2,O43865,O75494,P98179,Q16629,P08621,P07910,Q8IY67,P38159,P16989,Q15717,Q14011,P08670,Q92879,Q92900,Q13310,Q969T7,Q96E39,Q92804,Q06787,P51114,O00422,Q9Y5S9,O95319,O60506,P35637,P51003,P52298,Q07666,Q13868,P11940,P18615,Q96PU8 51 +Regulation of wound healing 0.3700827208594647 0.4386813169145329 0.6608924664652414 1.0 0.8295125729473658 15 P46108,Q16625,Q92766 3 +Regulation of t cell mediated immunity 0.4161236032746241 0.4381086060658 0.6613075561179571 1.0 0.8295995551811426 6 O15400,P04439 2 +Positive regulation by host of viral genome replication 0.3916999197681335 0.4364479713661783 0.6625117402659051 1.0 0.8305691873859675 5 P27105 1 +Kidney epithelium development 0.3954225407303425 0.4355696650761816 0.6631489839671911 1.0 0.8312055117774141 11 P80723,O94813 2 +Regulation of cellular response to insulin stimulus 0.3807543418769014 0.432970155379028 0.6650364516695402 1.0 0.8328511977080229 13 Q9HCD5,Q06481,P04899,Q8TBX8,P05771 5 +Blood vessel morphogenesis 0.293120104388096 0.4328692997183989 0.6651097244571949 1.0 0.8328511977080229 75 P42785,Q9H6E4,O94813,P09601,Q9NZ08,Q9Y4G8,P23634,Q96AY3 8 +Metencephalon development 0.3287611077073366 0.4328667342925669 0.665111588310042 1.0 0.8328511977080229 29 P46108,Q9BRK5,P54802,Q5KU26 4 +Negative regulation of nuclear division 0.3595954485653115 0.4317387822576912 0.665931277044217 1.0 0.8337147433307481 17 Q96DY7 1 +Glycolipid biosynthetic process 0.4004874205846059 0.4294650786697005 0.6675848022532302 1.0 0.8352954484566086 10 Q8NBX0,Q9Y2B2,O60762 3 +Regulation of multicellular organismal development 0.2737307956920831 0.4285086274686743 0.6682808536652916 1.0 0.8359979243204344 160 Q13614,P46379,O94813,Q9BUP3,Q16181,P12956,Q99956,Q9NZ08,Q9Y4G8,Q92896,Q13641,Q9UQB8,P23634,P80723,Q8N0X7,Q9GZS3,Q4KMQ2,P09601,Q15375,Q06481,P05771,P07948,Q9BXW9,O75844,O43290,Q9H2J4,Q96G23,P07196 28 +Dna strand elongation 0.3432801227598603 0.4274395837628983 0.6690591812424069 1.0 0.8359979243204344 20 P25205,Q9NRF9,P33991,P49005 4 +Dna methylation dependent heterochromatin assembly 0.3852624366832233 0.4202342828742433 0.6743143125406541 1.0 0.8399084755595729 12 Q15047 1 +Macroautophagy 0.2914076864855637 0.4200945707309521 0.6744163687527491 1.0 0.8399084755595729 88 Q96HY6,Q8NHS3,O43464,Q9H267,P60520,P09601,P21796,O15118,Q9Y487,Q8TBX8,Q93050,Q9Y5K8,O95817 13 +Positive regulation of microtubule polymerization or depolymerization 0.3656201502008964 0.4160239455434288 0.6773924812041159 1.0 0.8422256980276064 15 P36405,Q16625,P23396 3 +Regulation of cell morphogenesis 0.2857219339882367 0.4159795351672499 0.6774249783758881 1.0 0.8422256980276064 61 P35580,O75400,O75844,Q92766,P50570,Q16181,P46108,Q71RC2,Q96PU5,P35241,Q9UQB8,P84095 12 +Polyadenylation dependent rna catabolic process 0.4077516051276061 0.4157991997512167 0.6775569444931901 1.0 0.8422256980276064 7 Q96B26 1 +Actin filament based movement 0.3296248977200189 0.4153936904542334 0.6778537248244028 1.0 0.8422256980276064 22 Q9UM22,Q8WXH0,Q96PU5,P14649 4 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.4103024495427166 0.4148034581157565 0.6782857878523232 1.0 0.8423161109730434 6 P61978 1 +Animal organ regeneration 0.3608596538438888 0.4138659579098567 0.6789722760062857 1.0 0.8429618999032135 16 P50416,P09601 2 +Late endosome to vacuole transport via multivesicular body sorting pathway 0.3368932038835003 0.4129306965549541 0.6796573902084453 1.0 0.8435211508921647 3 Q96FZ7,Q9BRG1 2 +Regulation of mrna binding 0.4069904275543323 0.4127121607031161 0.6798175141199567 1.0 0.8435211508921647 7 Q86X55 1 +Associative learning 0.396568840239439 0.4123871141296 0.6800557064644042 1.0 0.8435672021950263 10 Q13641 1 +Regulation of microtubule polymerization or depolymerization 0.3278353765939751 0.4119432282715848 0.6803810351557389 1.0 0.8435672021950263 26 Q8IX90,Q8WWK9,P23396,Q16625,P29372,Q14203,Q7Z460,P36405,Q92974,P36404 10 +Regulation of er to golgi vesicle mediated transport 0.4066759365561374 0.4114386283901793 0.6807509340573783 1.0 0.8438625966559262 7 Q8WU17,Q9P2W9 2 +Response to hormone 0.2726013687760046 0.4087233509462439 0.6827426953525373 1.0 0.8449646141216893 166 P42785,O94813,O15118,Q15291,P04114,O15173,Q6IQ22,Q15392,P35241,Q9UQB8,O95831,P04899,Q96HY6,P09601,Q06481,O43823,Q8TBX8,P05771,P07948,P31751,P46108,P09960,Q05086,Q86X55,Q9NUQ7 25 +Regulation of lyase activity 0.4086676061774879 0.4083245061324053 0.6830354500783646 1.0 0.8449646141216893 6 P04899,Q13586 2 +Positive regulation of g1 s transition of mitotic cell cycle 0.3826192811728145 0.4080524252353105 0.6832351866129212 1.0 0.8449811974124686 12 Q96DY7,P35241 2 +Regulation of leukocyte apoptotic process 0.3754202132277303 0.4074939033353297 0.6836452710118848 1.0 0.8452131454485122 13 Q9HCL2,Q9Y4G8 2 +Negative regulation of leukocyte proliferation 0.4024358397957238 0.4067690638495859 0.6841776101894439 1.0 0.8454942127076027 8 P07948,Q96J02 2 +Mononuclear cell differentiation 0.3023787973086926 0.4059608334285333 0.6847713787301579 1.0 0.8460424780455891 42 P07948,Q9BXW9,P24390,P12956,P0CG08 5 +Cellular response to antibiotic 0.3612819682745161 0.4058058707777095 0.684885244708044 1.0 0.8460424780455891 4 P62829,P04637,Q04656 3 +Vacuolar transport 0.31294380114971 0.4020331806163503 0.6876596071692243 1.0 0.8475097254287114 37 Q96RL7,Q9NVJ2,Q96AX1,Q6IQ22,P11717,O15118,P20645,Q9Y2T2,Q14108,Q9H267 10 +Response to uv 0.3194587912990115 0.4015210532704143 0.6880365409518001 1.0 0.847811270184744 33 Q9BRK5,Q14011,Q96K76 3 +Sulfur compound biosynthetic process 0.2987615613870423 0.4003240542237515 0.6889178532629534 1.0 0.848570991432654 46 Q9NZL9,Q15118,Q13126,O95563,Q53GQ0,Q9UMR5,Q8NCH0 7 +Protein autoubiquitination 0.4007860196131079 0.3999815705041091 0.6891700908954586 1.0 0.8486172596971355 8 Q05086,Q96J02 2 +Dna dependent dna replication 0.2904284254660957 0.3985387302458557 0.6902331150404657 1.0 0.8490489862616359 78 Q9UNS1,Q9NRF9,Q9UJZ1,P41440,Q9BQP7,Q9UFC0,Q9Y619,Q9BRX5,Q96S55,Q13416,Q9BRT9,Q96RR1,P25205,P49005,P33991 15 +Protein o linked glycosylation 0.3618916142869334 0.3973278396836395 0.6911257203637737 1.0 0.8496578188591849 15 O60762,O60568,O60502,Q9Y2G5,O43505 5 +Regulation of non motile cilium assembly 0.4054454337515814 0.3956429205390411 0.6923684692833256 1.0 0.8509148015422899 6 P50570 1 +Regulation of striated muscle cell differentiation 0.3994766432403104 0.3946180476955923 0.6931247921742463 1.0 0.8512644010362376 8 P67809 1 +Regulation of behavior 0.3814766839378217 0.3939648570513873 0.6936069853414548 1.0 0.8512644010362376 5 P40763,Q96QK1,Q92769,P42345 4 +Metal ion export 0.3922431049707053 0.393756847618006 0.693760566460734 1.0 0.8512644010362376 10 P23634,Q4KMQ2 2 +Positive regulation of leukocyte apoptotic process 0.4021435916060127 0.3932119467536104 0.6941629467076544 1.0 0.8515579499923873 7 Q9Y4G8 1 +Negative regulation of posttranscriptional gene silencing 0.3811586964905166 0.3926643346276174 0.6945674159450392 1.0 0.8516023596418709 5 O75844 1 +Centromere complex assembly 0.3986439095026725 0.3912178587684483 0.6956362087780001 1.0 0.8524236471548425 8 Q6IPU0 1 +Cell junction maintenance 0.4042001036071588 0.3907735551717791 0.6959646237357853 1.0 0.8526630806854708 6 Q9BRK5,Q14203 2 +Ruffle assembly 0.3851425141764032 0.3896801139509615 0.6967731031357263 1.0 0.853490462660043 11 P84095,O95429 2 +Negative regulation of axon extension 0.3317152103559918 0.3892454970205841 0.6970945502474968 1.0 0.8536262197175494 3 Q9P265,Q00535 2 +B cell activation 0.309209845691123 0.3886610490136256 0.6975268996809056 1.0 0.8539242603045464 38 P07948,P17812,Q9UQ84,Q9NQT5,P02786,P05771,P78318 7 +Lipopolysaccharide mediated signaling pathway 0.4008497910463189 0.3880534599119845 0.6979764720273074 1.0 0.8543114733043804 7 Q8WTV0 1 +Positive regulation of immune effector process 0.3185440344389241 0.3860845460329816 0.6994340547056286 1.0 0.8546268186547997 32 P07948,Q7Z434,P09601,O15400,Q06481,O96028,Q9NQT5,Q9NUQ9,P02786,P04439 10 +Regulation of lymphocyte apoptotic process 0.3933187364412218 0.3829247557116995 0.7017755554111427 1.0 0.8560625282331518 9 Q9HCL2 1 +Lipid droplet organization 0.3995463383020025 0.3828769377020217 0.7018110118354466 1.0 0.8560625282331518 7 Q15042,Q96CS3,Q9NP72,Q9Y679,Q14534,Q8N0X7 6 +Respiratory burst 0.3557785691162044 0.3822089295402555 0.7023063989344429 1.0 0.8562289280701841 4 P32119,P18669,P63000 3 +Negative regulation of ion transport 0.3501334049359766 0.3818613884530852 0.7025641814086794 1.0 0.8563294167768843 17 Q9H1K1,Q12955,P21796,Q06787,Q96PU5,P28161 6 +Neural precursor cell proliferation 0.3227746260871916 0.3799222664503445 0.7040031182208724 1.0 0.8575940683762432 26 P07948,Q06481,O95456,Q9UKA9,P04899,Q92974 6 +Positive regulation of immunoglobulin production 0.3823335986936369 0.3773872336231059 0.7058858528213197 1.0 0.8584476368989808 11 P02786,O96028,Q9NQT5 3 +Ncrna catabolic process 0.3232774438107977 0.3771756851341594 0.7060430486320479 1.0 0.8584476368989808 22 Q9BQ61,Q5RKV6,Q96B26,Q9NQT5,Q08J23,Q99575 6 +Glandular epithelial cell differentiation 0.3544836516672 0.3767208990440576 0.7063810300134199 1.0 0.8584811695441112 4 Q86UL3,P19022,O00330 3 +Regulation of cellular protein catabolic process 0.2880102333258973 0.3766931410690507 0.7064016606615691 1.0 0.8584811695441112 87 Q96HY6,Q8N163,Q8NHS3,P46379,Q9UL46,Q9Y5A7,P60520,P51572,Q05086,P35241,Q92530 11 +Regulation of plasma lipoprotein particle levels 0.3489675678118139 0.3758233022875851 0.7070482629351011 1.0 0.8586925663914359 17 P09601,P61978,Q6PIU2,Q8WTV0 4 +Glucocorticoid metabolic process 0.3538361929426913 0.3739862901609657 0.7084145161736819 1.0 0.8598631033276465 4 Q04917,P05023,Q9UNE7 3 +Positive regulation of cellular component organization 0.2641037253945261 0.3719794157548378 0.7099081752844953 1.0 0.8608610298096132 224 O94813,O95429,Q16181,Q32P28,P61978,P21796,Q8NEY8,Q9Y4G8,Q14108,P50897,P02786,Q9Y3D6,Q13641,P17655,P41440,Q16625,Q96PU5,Q9UQB8,Q15047,P50570,Q08722,O43464,Q06481,Q13794,Q9UJX3,Q8TBX8,P07948,Q92766,Q71SY5,P31751,P07196 31 +Regulation of membrane potential 0.2872712506132391 0.3709307537850904 0.7106891083822249 1.0 0.8613191878861904 53 Q13794,P31751,Q96PU5,Q9UQB8 4 +Aspartate transmembrane transport 0.3751143482845443 0.368197121854083 0.7127262562572727 1.0 0.8631903234630595 5 Q8TDW0,O75746 2 +Cellular response to endogenous stimulus 0.2665806045602024 0.3647908319560256 0.7152675492501954 1.0 0.8653413625367827 209 P42785,O94813,O95429,O15118,Q9Y4G8,P04114,Q92896,O00459,P17655,O15173,Q6IQ22,P35241,Q9UQB8,P23634,Q8N0X7,O95831,P04899,Q92974,Q96HY6,Q9UNS1,Q6IAA8,P08670,P50570,Q06481,O43823,Q8TBX8,P05771,P33527,P28161,P07948,O95071,O75844,P31751,P46108,Q05086,Q86X55,Q9NUQ7 37 +Regulation of neurogenesis 0.2916187050236316 0.3646698601372679 0.7153578596072405 1.0 0.8653413625367827 49 P07948,O94813,Q9NUL3,Q15375,Q06481,Q9Y4G8,Q9UQB8,Q8N0X7,Q96G23,P07196 10 +Regulation of insulin receptor signaling pathway 0.3787327200101641 0.3617922435424306 0.717507288831108 1.0 0.8672867662469174 11 Q8TBX8,P05771,P04899,Q9HCD5 4 +Cellular response to alkaloid 0.3501381753596806 0.3584898237551793 0.7199767820089926 1.0 0.8691245146285579 4 P28161 1 +Protein localization to nuclear envelope 0.3952529395442433 0.3563349708245085 0.7215897228842434 1.0 0.870242036329227 6 Q7Z3B4,Q5JTV8,P53350 3 +Embryo development 0.2683019400558961 0.3549640260135194 0.7226165416453592 1.0 0.8708351253895003 191 Q9H6E4,P46379,Q16181,P23786,Q9BZK7,O43772,Q9BRT9,P04114,Q96AY3,Q08J23,P42892,Q03164,Q9H0G5,Q9NR56,P67809,P80723,Q9Y3Y2,P16989,Q92879,Q9Y5P4,P14635,O43819 22 +Response to topologically incorrect protein 0.2772355440603319 0.3529876950557382 0.7240976654456235 1.0 0.8721281539846762 58 Q7Z2K6,P46379,Q96HY6 3 +Negative regulation of cysteine type endopeptidase activity 0.3246893891114283 0.3524024738030555 0.7245364470079032 1.0 0.8724926968477662 21 Q96K76,P78318 2 +Positive regulation of neuron death 0.3442541091016908 0.3516675169747627 0.7250876240505817 1.0 0.8729924248993668 17 O95831,P17655 2 +Protein targeting to vacuole 0.3758212925307902 0.3493221314828953 0.726847485198393 1.0 0.8735131411806087 11 Q96RL7,P20645,Q14108 3 +Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway 0.2982853445486824 0.349252426362362 0.7268998105833826 1.0 0.8735131411806087 2 Q15233 1 +Regulation of mitochondrial electron transport nadh to ubiquinone 0.2982853445486797 0.3492524263623496 0.7268998105833919 1.0 0.8735131411806087 2 Q9H1K1 1 +Muscle system process 0.2874377690326634 0.3484332106300476 0.7275148648026759 1.0 0.8735131411806087 51 P46939,O43819,Q86U42,P67936,Q9Y5P4,P09601,Q13555,P28289,Q96PU5,P23634,P14649,P28161 12 +Arf protein signal transduction 0.3223716371661408 0.3476523048499708 0.7281013199833422 1.0 0.8735131411806087 3 Q92538 1 +Developmental growth involved in morphogenesis 0.3053770162118592 0.3465198998493325 0.7289520315940725 1.0 0.8736312737632943 37 O94813,Q96PU5,P50570 3 +Activation of protein kinase activity 0.3750695642524563 0.3461230356081597 0.729250252236241 1.0 0.8736312737632943 11 Q99627 1 +Regulation of intracellular protein transport 0.2830093404780165 0.343587659731517 0.7311564064409097 1.0 0.8740605306389838 69 Q99653,Q8NBM4,O95429,P50402,O75312,P55786,Q9Y3D6,O00459,Q12955,O00410,Q7Z434,Q9NW64,O95817,Q99496,Q7Z3B4,O43464,P27105,Q96DZ1,O95071,Q9Y385,P31751,P51572,Q9Y282,P06493 24 +Mitochondrial electron transport nadh to ubiquinone 0.3157729485703889 0.3430789209518705 0.7315390884747326 1.0 0.8740968920082833 28 O95182,P51970,O75380,O43678,Q9Y375,P03886,O43676,O96000 8 +Mrna 3 splice site recognition 0.3463904176108729 0.3430033809807873 0.731595916634078 1.0 0.8740968920082833 4 Q15459,Q12874,Q15637 3 +Nucleoside triphosphate metabolic process 0.2932566920464285 0.342078206621741 0.7322920378000215 1.0 0.8746025642441099 44 Q9H773,P00846 2 +Intracellular sterol transport 0.3830335733229636 0.3409864197557779 0.733113805213111 1.0 0.875118015715549 9 O15118 1 +Leukocyte homeostasis 0.3610453579971993 0.3409606710804772 0.7331331894528079 1.0 0.875118015715549 13 Q9HCL2,Q13794 2 +Cellular response to biotic stimulus 0.3137280575782168 0.3398819844269638 0.7339454042086655 1.0 0.8756167910322398 30 P07948,O75844,P17655,P08670,Q86U42,O43823,Q8WTV0,Q9NUQ9 8 +Negative regulation of microtubule polymerization or depolymerization 0.3733667504266844 0.3389083925641074 0.7346787418676468 1.0 0.8759477836554813 11 P29372,Q8WWK9,Q92974 3 +Regulation of response to stress 0.261158838015211 0.3378951845562711 0.7354421765310106 1.0 0.8760086849046614 229 P46379,Q9HBM6,P12956,P29372,P61978,Q9NZ08,Q9Y3Z3,Q96K76,Q9BUP0,P60900,P23396,P67809,Q16625,Q7Z434,Q96S55,P28070,P38398,P23634,P18887,Q92974,Q96HY6,Q9UNS1,P16989,Q96J02,Q92879,Q4KMQ2,Q08722,O43464,Q06481,Q13794,P08183,Q9NXR7,P07948,Q8N163,Q9BXW9,P33527,Q92766,O95071,O75844,Q14166,P51572,P46108,O96028,P04439,Q96G23,P78318 46 +Male meiosis i 0.3200647249190984 0.3376239879545869 0.7356465628453726 1.0 0.8760086849046614 3 P54652,O43502 2 +Hyperosmotic response 0.3785756121933153 0.3365469838887697 0.7364584275808719 1.0 0.8766385368232849 10 Q9BUP0,P16989 2 +Regulation of extracellular matrix organization 0.3194174757281603 0.3348282195826144 0.7377546718522041 1.0 0.8775289672683478 3 Q7Z460,Q8NBJ5 2 +Positive regulation of extracellular matrix organization 0.3194174757281603 0.3348282195826144 0.7377546718522041 1.0 0.8775289672683478 3 Q7Z460,Q8NBJ5 2 +Regulation of translation at synapse modulating synaptic transmission 0.3441243120750956 0.3337494728540157 0.738568614004695 1.0 0.8775289672683478 4 P06730,Q7L576,P35268 3 +Response to toxic substance 0.2815206901939843 0.3315163187710642 0.7402545166484753 1.0 0.8790350966500049 54 P07948,O43464,P07099,Q15165,O95831,Q5VT66,P08183 7 +B cell proliferation 0.3805679078749194 0.3311520214814081 0.7405296587619361 1.0 0.8791989465945566 9 P07948,P02786 2 +Positive regulation of cytoskeleton organization 0.2918195969199068 0.3305339282826982 0.7409965607449811 1.0 0.8794275049759912 44 Q9UHV9,O95429,P23396,Q08722,Q16625,Q14203,Q7Z460,P36405,P62993,Q9Y281,P14373,Q7L576,Q9UQB8,P09493,P36404 15 +Response to ketone 0.3062774024473498 0.3298073132039861 0.741545561150605 1.0 0.8797532939062332 35 O94813,Q13126,Q05086,O43823,O95831,P07196 6 +Mitochondrial electron transport ubiquinol to cytochrome c 0.3421819359015816 0.3258852360930426 0.7445111863620333 1.0 0.8813957095922919 4 Q9UDW1,O14949,P08574 3 +Establishment of protein localization to vacuole 0.364131178459378 0.3256950578078147 0.7446550838290826 1.0 0.8813957095922919 12 Q96RL7,P20645,Q14108 3 +Lysosomal transport 0.308324075837071 0.3252491607219374 0.7449925046132664 1.0 0.8813957095922919 33 Q9NVJ2,Q96AX1,Q6IQ22,P11717,O15118,P20645,Q9Y2T2,Q14108,Q9H267 9 +Mitophagy 0.3573154982977527 0.3242487209138248 0.7457497388726779 1.0 0.8819840328857902 13 O43464,P21796 2 +Base excision repair 0.3465879072068635 0.3230503868952398 0.7466570828542645 1.0 0.8823878873701761 15 P29372,P23396,Q96K76 3 +Protein k48 linked ubiquitination 0.369315171200952 0.3219242660548326 0.7475100693222889 1.0 0.8827018684544521 11 Q05086,Q96PU5 2 +Regulation of cell cycle phase transition 0.2797756232078203 0.3211226082525121 0.7481174779758746 1.0 0.8830718472904365 100 Q96HY6,Q9UNS1,Q8N163,Q9UL46,P14635,Q9Y619,Q06481,P35241,P23634,Q9UJX3,Q96DY7,Q08J23,Q96K76,Q9NXR7 14 +Ruffle organization 0.3497179548725382 0.320962125763588 0.7482390928617801 1.0 0.8830718472904365 14 P84095,O95429 2 +Cellular iron ion homeostasis 0.3461168432358773 0.3208316773088515 0.7483379523372311 1.0 0.8830718472904365 15 Q9Y487,P09601 2 +Regulation of chromatin organization 0.3335719105235122 0.3202988134262094 0.7487418225659686 1.0 0.8831867325499845 18 Q15047 1 +Ceramide metabolic process 0.3335442315141448 0.3201578719422449 0.7488486570061101 1.0 0.8831867325499845 18 O43464,Q9Y5P4,Q96G23,Q8NCC3 4 +Negative regulation of intracellular protein transport 0.3556212705440955 0.3167379726236076 0.7514424331421612 1.0 0.8852685161627004 13 Q9Y385,Q8NBM4,O95429,Q96DZ1,O95817 5 +Male gamete generation 0.2815587811634898 0.3163602211467684 0.7517291065131135 1.0 0.8852808327666835 72 P16989,P46379,Q15102,P50570,Q16181,O75718,Q9P0K7,P51572,P11717,O95470,P23634,P04114,Q08J23 13 +Non lytic viral release 0.3612638353661624 0.3140668767238316 0.7534702461422682 1.0 0.8861916106003558 5 Q9NVJ2 1 +Histone mrna catabolic process 0.3389446422790449 0.3129202069331272 0.7543412850828177 1.0 0.8865653900588305 4 Q01780,Q9NVV4,Q92900 3 +Negative regulation of lipid metabolic process 0.3545408989631445 0.3119753301781771 0.7550592719734404 1.0 0.8870009862424417 13 P49748,Q8TBX8 2 +Thioester biosynthetic process 0.3111859450517446 0.3088868900963892 0.7574075696828437 1.0 0.8887904178931623 26 O95563,Q9UMR5,Q53GQ0,Q15118 4 +Developmental cell growth 0.3016917109965559 0.3085506647918933 0.7576633544878839 1.0 0.8887904178931623 36 O94813,Q96PU5,P50570 3 +Negative regulation of hormone secretion 0.3823243097104131 0.308386145273436 0.7577885230698342 1.0 0.8887904178931623 6 Q16836,Q6WKZ4 2 +Positive regulation of b cell mediated immunity 0.3747526072770469 0.3083133136703969 0.7578439363255516 1.0 0.8887904178931623 9 P02786,O96028,Q9NQT5 3 +Response to growth factor 0.282162447017827 0.3079991061318862 0.7580830125034277 1.0 0.8887904178931623 87 O94813,P50570,O95429,O43464,Q96F07,Q05086,Q06481,Q9Y4G8,Q9UQB8,P23634,P35241,P05771,Q92896 13 +Vesicle mediated transport to the plasma membrane 0.2883391880269785 0.3078773466774401 0.758175663812763 1.0 0.8887904178931623 45 Q15904,Q9BZG1,P50570,Q9Y2D4,Q12955,Q4J6C6,O60826,P36405,O15027,P42566,Q13277,Q8N2H4 12 +Attachment of mitotic spindle microtubules to kinetochore 0.3771519820632957 0.3066251847097857 0.7591286818482992 1.0 0.8890946191572443 8 Q96EE3 1 +Regulation of tor signaling 0.3708211876727174 0.3053038870168805 0.7601347157666627 1.0 0.8900518805850176 10 O75844,Q6IAA8,Q96EE3,Q9P2J5 4 +Phosphatidylinositol metabolic process 0.3109376278334622 0.3049242745103667 0.7604238272454613 1.0 0.8900518805850176 23 Q13614,O00459,Q9Y2B2,Q10713,Q8TBX8,O60762 6 +Response to oxidative stress 0.2799366988608839 0.3047196459924368 0.7605796854517191 1.0 0.8900518805850176 95 Q7Z2K6,Q99720,P60602,P30519,P09601,Q15165,Q05086,O95831,P28074 9 +Regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.3104243874670856 0.3028196564821079 0.7620273026245314 1.0 0.8910888166938445 25 Q92896 1 +Mrna 5 splice site recognition 0.3363548073810184 0.3026790057626512 0.7621344987085197 1.0 0.8910888166938445 4 Q07955,P09234,O75475 3 +Chromosome condensation 0.3102877579316447 0.3020176969733759 0.7626385722905509 1.0 0.8910888166938445 25 P53350,O95831,Q96FF9,Q9ULX6,O43823,P06493,Q9NTJ3 7 +Regulation of peptidyl tyrosine phosphorylation 0.3100334270813578 0.3004139718707893 0.7638614075832153 1.0 0.8920298091835326 22 P07948,Q96FZ7,Q15375,Q13432,Q9H2J4,Q92974 6 +Copi coated vesicle budding 0.3357073486565136 0.3001372208637197 0.7640724890459043 1.0 0.8921137804707189 4 Q92538,P49755,Q9BVK6 3 +Regulation of b cell mediated immunity 0.3638251230119384 0.299333802648624 0.764685365473035 1.0 0.8921262359313135 11 P02786,O96028,Q9NQT5 3 +Astral microtubule organization 0.3353836192942648 0.2988691341668837 0.7650398986762865 1.0 0.8922681496570226 4 Q7Z460,P15311,Q14980 3 +Response to insulin 0.2749049258438406 0.2984806918250382 0.7653363105748916 1.0 0.8924514736738322 56 O00459,P07948,P31751,Q16836,Q6IQ22,Q9HCD5,Q9H1E3,Q06481,P05771,Q9UQB8,Q8TBX8,P04899 12 +Negative regulation of histone h3 k9 methylation 0.3351572909220744 0.2979836935910197 0.7657156092252337 1.0 0.8925789616742695 4 Q12824 1 +Organic cyclic compound catabolic process 0.2656896770823496 0.2947640439830811 0.768174135400228 1.0 0.8944076574456179 163 P11940,Q96C86,Q9Y3B2,Q13126,Q5RKV6,Q7L8L6,Q6NZY4,P30519,Q96B26,Q9Y3Z3,Q9H773,P98175,Q9NQT5,Q08J23,Q99729,Q9HCE1,Q9Y4Y9,P67809,Q9BQ61,Q6P6C2,P62312,P07910,O95831,Q99575,Q9UK45,P16989,Q15717,Q14011,P08670,Q92879,Q13310,P09601,Q969T7,Q92804,P51114,P49902,Q9BPU6,Q9Y5S9,Q8WTV0,Q9NRN7,P33527,Q8IYS1,Q9H814,P53004,P52298,P21964,O60506,O43598 48 +Rna catabolic process 0.265621628605092 0.2945905664828581 0.7683066693978535 1.0 0.8944076574456179 119 Q96C86,Q9Y3B2,Q9HBH5,Q5RKV6,Q7L8L6,Q6NZY4,Q96B26,P98175,Q9NQT5,Q08J23,Q99729,Q9HCE1,Q9Y4Y9,P67809,Q9BQ61,Q6P6C2,P62312,P07910,Q99575,P16989,Q9UK45,Q15717,Q14011,P08670,Q92879,Q13310,Q969T7,Q92804,Q06787,P51114,Q9Y5S9,O60506,P35637,Q9H814,P52298,Q13868,P11940 37 +Regulation of protein stability 0.275979652682325 0.2937367487235333 0.7689590709600764 1.0 0.8944133600615981 104 Q96HY6,Q8N163,P83436,P46379,O95429,P41440,Q32P28,O75718,P48449,Q96PU5,Q9H2J4,O95817,Q96K76 13 +Necrotic cell death 0.3401902035683787 0.2932902756397802 0.7693002859216773 1.0 0.8946325893973062 15 P16989,P00403,Q92974 3 +Regulation of ion transport 0.2806395941545829 0.2924684345747876 0.7699284908850856 1.0 0.895171963078802 77 P07948,O75844,P50570,Q4KMQ2,Q13555,P21796,P0CG08,Q96PU5,P27105,P23634,P04899,P08183,P28161 13 +Response to estrogen 0.3500272687901056 0.2923088710846172 0.7700504767265892 1.0 0.895171963078802 13 Q15291,Q969T9,P09601 3 +Regulation of dephosphorylation 0.3087052656697582 0.2921354618699562 0.770183054037378 1.0 0.895171963078802 24 Q13614,P04899,O95429,P78318 4 +Positive regulation of molecular function 0.2500537262963645 0.2906303794851964 0.7713340230360921 1.0 0.8957208478719195 259 Q9P0J0,Q9UL46,Q86U42,P12956,P61978,Q9BRT9,Q9Y4G8,Q03164,P02786,P84095,Q16763,Q9Y3D6,P23396,P41440,Q8IXB1,Q99627,Q13432,P23634,Q96M27,O95831,P04899,Q92974,Q9BTE7,Q96HY6,Q9Y3Y2,P50570,O43464,Q96F07,O75503,Q15375,Q13794,Q8WTV0,P14635,Q12824,P05771,P08183,P28161,P07948,Q71SY5,P31751,P60520,Q9BRX5,P51572,P46108,Q66K14 45 +Positive regulation of organ growth 0.3771804446847552 0.2899527132230767 0.7718524136126208 1.0 0.8957208478719195 6 P16989 1 +Columnar cuboidal epithelial cell development 0.3545984455958525 0.2890574080580834 0.7725374463667181 1.0 0.8959886904310659 5 Q86UL3,P19022,P04818,Q9NQ88 4 +Positive regulation of protein containing complex assembly 0.2806048468203563 0.2889113410859079 0.7726492247166772 1.0 0.8959886904310659 51 Q71SY5,P23396,O95429,Q16625,P36405,Q9UQB8,P02786 7 +Lamellipodium morphogenesis 0.3545399858120995 0.288841224882422 0.7727028831049816 1.0 0.8959886904310659 5 Q92766,O60749 2 +Regulation of lipid storage 0.3691504483108409 0.2868038657118291 0.7742625028291044 1.0 0.8972954001009458 9 P50416,Q8WTV0 2 +2 oxoglutarate metabolic process 0.3660225849089695 0.2864475292373382 0.7745353759517153 1.0 0.8972954001009458 10 P48735,Q8TD30 2 +Regulation of smad protein signal transduction 0.3074433656957981 0.2845888973008419 0.7759591183395196 1.0 0.8981552495614482 3 Q8N1F7,Q01082 2 +Single strand break repair 0.3074433656957969 0.284588897300837 0.7759591183395234 1.0 0.8981552495614482 3 P18887,Q15554 2 +Adipose tissue development 0.3599036565011769 0.2835087388888311 0.7767868836926493 1.0 0.8984489217737066 11 Q9BZK7,O15173 2 +Fibroblast growth factor receptor signaling pathway 0.3529792746113968 0.2830905523837999 0.7771074236092379 1.0 0.898657511335958 5 P35222,Q8NEM2,P46109,P46940 4 +Endosome organization 0.3165228197990236 0.2800405789842687 0.7794463723578908 1.0 0.9005499723889834 20 Q9H267,P51790,Q14108 3 +Positive regulation of lymphocyte mediated immunity 0.3369549780587648 0.2785574100341725 0.7805845012370711 1.0 0.9015399374647974 15 Q9NQT5,O15400,O96028,Q9NUQ9,P02786,P04439 6 +Response to heat 0.3020297995649242 0.2768340764400951 0.781907514118217 1.0 0.9021162982390644 32 O43464,P09601,O95817 3 +Negative regulation of stress activated protein kinase signaling cascade 0.3634834719477792 0.2766241946317427 0.7820686847604494 1.0 0.9021162982390644 10 P78318 1 +Cellular pigmentation 0.3522877938777991 0.275876848583931 0.7826426562805064 1.0 0.9026159458002962 12 Q9BXS5,Q96AX1,O60315,Q9H267,Q13561 5 +Regulation of protein containing complex disassembly 0.2979866993966811 0.2733746102468041 0.7845652677969561 1.0 0.9040200191584556 35 O75844,Q13045,P29372,P28289,Q9UEY8,P35241,Q92974 7 +Cell junction assembly 0.2724593230488723 0.2706702732177174 0.7866446421405637 1.0 0.905614282908902 63 P41440,Q16625,Q13641 3 +Sarcoplasmic reticulum calcium ion transport 0.371675277368833 0.2706564467824146 0.7866552772600259 1.0 0.905614282908902 6 P28161 1 +Negative regulation of cyclin dependent protein serine threonine kinase activity 0.369249003305554 0.2689562229853188 0.787963370708475 1.0 0.9061437399069472 7 P42771,O00410,P53350 3 +Regulation of homotypic cell cell adhesion 0.3707656519640252 0.2675123445520018 0.7890747108265828 1.0 0.907083774503586 6 P07948,P35241 2 +Cellular response to increased oxygen levels 0.3704485832756871 0.2664194002647977 0.7899162257326215 1.0 0.907083774503586 6 Q9Y487,Q8N511 2 +Endoplasmic reticulum tubular network organization 0.3439395612495932 0.2663970440233115 0.7899334415318178 1.0 0.907083774503586 13 Q9BRK0 1 +Nervous system process 0.2785646245393519 0.2663847061740553 0.7899429425437399 1.0 0.907083774503586 87 Q13614,Q9BPW8,Q96KQ7,Q14108,P50897,Q13641,Q6P4Q7,Q13432,O00264,Q9UQB8,P23634,O14773,Q8N0X7,Q9BRK0,Q99808,P28161,O75844,Q9H6K4,Q05086,P62072,P07196 21 +Regulation of cellular carbohydrate metabolic process 0.3039044333930512 0.2660808512951328 0.7901769420283904 1.0 0.907083774503586 26 Q15118,P31751,Q9BYT8,Q13794,Q14108 5 +Ameboidal type cell migration 0.2754345522225794 0.265936183312348 0.7902883578924782 1.0 0.907083774503586 69 P42785,O94813,Q13641,P09601,Q8WTV0 5 +Negative regulation of signaling receptor activity 0.3699384515711022 0.2646642279521454 0.7912681369887014 1.0 0.9076931298016327 6 Q96FZ7,Q99816,Q9BRG1,P30533,Q9UNH7 5 +Cellular response to light stimulus 0.3031648878443812 0.2634421167607504 0.7922098322095339 1.0 0.9084993483374598 27 Q96K76 1 +Negative regulation of intrinsic apoptotic signaling pathway 0.2977444839116042 0.2633517672328681 0.7922794629027146 1.0 0.9084993483374598 34 Q8N163,P16989,Q9P0J0,Q9HBM6,O43464,P45880,Q96K76 7 +Response to peptide 0.27836332109241 0.2627539974147333 0.7927401946517736 1.0 0.9087025478751554 86 O00459,Q16836,Q6IQ22,Q9H1E3,Q9UQB8,P04899,Q92974,Q9UNS1,P08670,Q06481,Q8TBX8,P05771,P33527,P07948,P31751,P46108,Q9HCD5,P09960,Q96RT1,P07196 20 +Modulation by host of viral genome replication 0.3663174827022377 0.2586511240100151 0.7959044338269523 1.0 0.9116004601278044 7 Q9H1E3,P27105 2 +Cellular response to peptide hormone stimulus 0.2717975008190798 0.2566078587519489 0.7974815077024335 1.0 0.9128315114951068 55 O00459,P07948,P31751,P46108,Q9HCD5,Q6IQ22,Q9H1E3,Q06481,P05771,Q9UQB8,Q8TBX8,P04899 12 +Heterotypic cell cell adhesion 0.3579616934807864 0.2556432131226232 0.7982263475879012 1.0 0.9133578879040428 10 P41440 1 +Transmembrane receptor protein tyrosine kinase signaling pathway 0.2712808571093907 0.2527759240272191 0.800441373477832 1.0 0.9153070139624838 64 O00459,P07948,Q96F07,P31751,P46108,Q9HCD5,P11717,Q9H1E3,Q15375,Q96RT1,P05771,O95470,Q9Y4G8,Q9UQB8,Q8TBX8,P04899 16 +Histone h2b ubiquitination 0.3660511823777175 0.2514233346448671 0.8014868285650056 1.0 0.9162708348674312 6 O75150,Q5VTR2,Q6PD62,P50750,Q6P1J9 5 +Exocytic process 0.3306195433149835 0.2503551771752519 0.8023126894552197 1.0 0.9168879193096734 15 Q6IQ22 1 +Basement membrane organization 0.3435880829015523 0.2493584450472295 0.8030835260805169 1.0 0.9176052410296104 5 Q7Z460,O60568,Q9NPQ8,P07942 4 +Positive regulation of phospholipid metabolic process 0.3434295889585392 0.2488023287265572 0.803513689678998 1.0 0.9179331225881978 5 Q9UJZ1 1 +Exit from mitosis 0.3508791768960727 0.2481288241949179 0.8040347343518934 1.0 0.9183505608931776 11 Q16763 1 +Late endosome to vacuole transport 0.3429554573737098 0.2471413915518523 0.8047988012289806 1.0 0.918582677328662 5 Q99570,Q96FZ7 2 +Regulation of early endosome to late endosome transport 0.3581846641221039 0.2461878331797581 0.8055368334903301 1.0 0.919261367753786 9 Q13614 1 +Isoprenoid biosynthetic process 0.3644195936782425 0.2459372211886434 0.8057308301910251 1.0 0.9193190853550144 6 P48449 1 +Leukocyte apoptotic process 0.3046956913306384 0.2437001028654512 0.8074630936956355 1.0 0.9210819656135064 21 P24390,Q9HCL2,Q9Y4G8 3 +Selective autophagy 0.3000613854464315 0.2435707510251153 0.8075632834240103 1.0 0.9210819656135064 24 Q96HY6,Q86VR2,O43464,P21796,O95817 5 +Negative regulation of cell cycle 0.2765341119689459 0.2431945028427176 0.8078547251501487 1.0 0.9210865863060216 80 Q9UNS1,P14635,Q9Y619,Q96DY7,Q08J23,Q96K76,Q9NXR7 7 +Cellular response to oxygen containing compound 0.2620414001747274 0.242805939525987 0.8081557341673091 1.0 0.921217277472156 188 O94813,Q9P0J0,Q86U42,Q99720,Q9Y4G8,O00459,P17655,P23396,P60602,Q6IQ22,Q9UQB8,P23634,O95831,P04899,Q5KU26,Q92974,Q9UNS1,Q6IAA8,P08670,P50570,O95563,O43464,Q06481,Q96RR1,O43823,Q99808,Q8WTV0,Q8TBX8,Q12824,P05771,P33527,P07948,P50416,P31751,P46108 35 +Mrna catabolic process 0.2741859985229108 0.2424900097076177 0.8084004970016969 1.0 0.921217277472156 98 Q96C86,Q5RKV6,Q7L8L6,Q96B26,P98175,Q9NQT5,Q99729,Q9HCE1,Q9Y4Y9,P67809,Q6P6C2,P62312,P07910,P16989,Q9UK45,Q15717,Q14011,P08670,Q92879,Q13310,Q969T7,Q92804,Q06787,P51114,Q9Y5S9,O60506,P35637,P52298,Q13868,P11940 30 +Positive regulation of phosphorus metabolic process 0.2675137549757529 0.2417111726414061 0.8090039717163444 1.0 0.9217411053504742 112 Q92990,O95429,P12956,Q9Y4G8,Q9UJZ1,P02786,Q8IZP0,P17655,P23396,P41440,Q7Z434,Q99627,Q13432,P23634,Q96M27,P30040,Q92974,Q96HY6,Q86XL3,P00403,O75746,P54652,Q06787,P51114,Q15375,Q8NDZ4,P14635,P07948,P53350,P31751,Q9NQ88,Q9Y4R8,P54619,Q92797 34 +Regulation of ruffle assembly 0.3589097581870191 0.2402112234553517 0.8101665133144349 1.0 0.922573698764528 8 P84095 1 +Regulation of organelle assembly 0.2733584146505276 0.2369092849522687 0.8127271666692795 1.0 0.924012262921263 52 P50570,Q16181,P53350,O75396,Q9P2W9,P38398,P35241,Q96KQ7,Q8TBX8,Q66K14,Q8WXH0 11 +Response to temperature stimulus 0.2800263832855439 0.2353369436342059 0.8139472233062632 1.0 0.9246998662043902 43 P49748,Q14011,O43464,P09601,Q06481,O95817 6 +Ribonucleoprotein complex disassembly 0.3393782383419666 0.234740444708129 0.8144101943356605 1.0 0.9249414148992884 5 P33176,Q14562,Q07866,Q9UBB9 4 +Facultative heterochromatin assembly 0.3267924487141229 0.2337525762279835 0.8151770683013397 1.0 0.9253205255554432 15 Q15047 1 +T cell differentiation 0.2979458125599157 0.2329049774625798 0.8158351932664094 1.0 0.9257952865318178 23 P24390,Q9BXW9,P0CG08 3 +Interleukin 2 production 0.3563303195605404 0.2312663543000267 0.817107883580606 1.0 0.9268484783083952 8 Q9UJZ1,P15311,Q92990,P23396 4 +Macromolecule deacylation 0.2855630599010288 0.2309758816660037 0.8173335390867591 1.0 0.9268484783083952 39 Q8N163,Q8WXI9,Q9ULX6,Q9BZK7,O43823,P50897,Q9UMR5 7 +Positive regulation of leukocyte mediated immunity 0.3068390053875425 0.2309022927623165 0.8173907094972477 1.0 0.9268484783083952 20 Q7Z434,O15400,O96028,Q9NQT5,Q9NUQ9,P02786,P04439 7 +Cytoplasmic sequestering of nf kappab 0.3167728513223015 0.2292858483401209 0.8186467519150631 1.0 0.9277803535671064 4 O60826 1 +Axon extension 0.2967590666117892 0.2281518534712144 0.8195281896814763 1.0 0.9278601156459788 22 O94813 1 +Integrin mediated signaling pathway 0.3252473250947559 0.2271453942863185 0.8203106868877084 1.0 0.9278601156459788 15 Q96RT1,Q03001,P35579,Q08722 4 +Endosome transport via multivesicular body sorting pathway 0.3371113989637285 0.2270030769917242 0.8204213495312636 1.0 0.9278601156459788 5 O43633,Q96FZ7,Q9BRG1,P55072 4 +Multivesicular body sorting pathway 0.3371113989637285 0.2270030769917242 0.8204213495312636 1.0 0.9278601156459788 5 O43633,Q96FZ7,Q9BRG1,P55072 4 +Cell cycle g1 s phase transition 0.2751146444051884 0.2266080680036308 0.820728518129461 1.0 0.9278601156459788 49 Q96HY6,Q9UL46,P49321,Q06481,P35241,P23634,Q96DY7 7 +Respiratory electron transport chain 0.2655040270205984 0.2265534356995995 0.8207710037035625 1.0 0.9278601156459788 57 Q7KZN9,O95182,O43819,P51970,P14635,P06493,P00403,O75380,P21912,O43678,Q9Y375,P03886,P13073,O43676,O96000 15 +Stem cell division 0.3159598575590718 0.2264024646201129 0.820888411205662 1.0 0.9278601156459788 4 P43034,Q13618,Q01085 3 +Positive regulation of mirna transcription 0.3159598575590689 0.2264024646201023 0.8208884112056702 1.0 0.9278601156459788 4 P40763,P04637,P51532 3 +Kidney morphogenesis 0.3580568948753233 0.2249573736428615 0.8220124352370073 1.0 0.9284757198007432 6 P80723 1 +Fatty acyl coa biosynthetic process 0.3335038092225148 0.2237224961645872 0.8229732401844849 1.0 0.9292334806381096 13 Q9UMR5,Q53GQ0 2 +Deoxyribonucleotide biosynthetic process 0.353686825356996 0.2222204894048369 0.8241422446104112 1.0 0.9298139266204588 8 P55263 1 +Mitotic cell cycle checkpoint signaling 0.28719388041795 0.2203384447480962 0.8256075812071493 1.0 0.9304250564727824 37 Q68E01,Q9BXW9,P53350,Q13564,Q9Y619,P38398,Q96JB5,P06493,P14635,O60566,Q9NXR7 11 +Non motile cilium assembly 0.3483186742285223 0.2203157824309471 0.8256252295190618 1.0 0.9304250564727824 10 P50570 1 +Keratan sulfate metabolic process 0.2905879267536226 0.2190714462999314 0.8265943930715245 1.0 0.9308626246641728 3 O43505 1 +Cellular response to insulin stimulus 0.2756767643895373 0.2187260205011816 0.8268634783016915 1.0 0.9310020895685652 47 O00459,P31751,Q9HCD5,Q6IQ22,Q9H1E3,Q06481,P05771,Q9UQB8,Q8TBX8,P04899 10 +Nuclear pore organization 0.3373705586646127 0.2168838495875866 0.8282988642094073 1.0 0.9321270575109376 12 P57740,Q96EE3,Q8N1F7 3 +Potassium ion transport 0.3038647402251195 0.2163293035806963 0.8287310688598848 1.0 0.932449736947843 20 Q96PU5 1 +Negative regulation of vascular associated smooth muscle cell migration 0.2897033529847409 0.2158148266775679 0.8291320906360826 1.0 0.9326228641609036 3 Q14344 1 +Endoplasmic reticulum unfolded protein response 0.2943506764569415 0.213866993517679 0.8306507800616614 1.0 0.9339539554806612 23 Q7Z2K6 1 +Rho protein signal transduction 0.3111445491077012 0.2119717756542096 0.8321290537375781 1.0 0.9343764499057556 18 P41440,P84095 2 +Secondary metabolic process 0.3482687297832813 0.2112727478778996 0.8326744469993732 1.0 0.9347536261411528 9 P40616,Q9Y4G8 2 +Aspartate family amino acid metabolic process 0.2981246336122431 0.2103578389954077 0.8333883960116377 1.0 0.9352275242357488 21 Q9BQT8,Q13126 2 +Response to fibroblast growth factor 0.3530936183997452 0.2090624538426463 0.8343994845122948 1.0 0.9356342236816964 6 P48506,P46940,P35222,Q8NEM2,P46109 5 +Interferon gamma production 0.3496585522142448 0.2086765890230041 0.8347007170457454 1.0 0.9356342236816964 8 Q9NUQ9,P04439,Q08722 3 +Signal transduction by p53 class mediator 0.2724887148222784 0.2056810344803146 0.8370400741037514 1.0 0.937512404774274 49 Q13794,P46379,Q9NWT1 3 +Protein peptidyl prolyl isomerization 0.2923476924333023 0.2053072517773559 0.8373320786410325 1.0 0.937512404774274 22 O95302,Q9NWM8 2 +Negative regulation of autophagy 0.2917793278469789 0.2024092059691029 0.8395968320297149 1.0 0.9387433618193743 22 P09601 1 +Positive regulation of histone acetylation 0.3505034209552727 0.2009357368433852 0.8407488235917921 1.0 0.9398674501610372 6 Q969T9,Q12824 2 +Histone h3 k9 modification 0.3271921721253656 0.1990511313256564 0.8422227477553588 1.0 0.9402508534222132 13 Q15047,Q03164,Q12824,Q96KQ7 4 +Regulation of release of cytochrome c from mitochondria 0.337238549058047 0.1976006806753367 0.8433575022033206 1.0 0.94065105083057 11 O00429,Q96A26,Q13794 3 +Negative regulation of nucleotide metabolic process 0.3075428941404914 0.1973703476149331 0.8435377323688156 1.0 0.9406883897849876 4 P40763,Q9NQ88,O75376 3 +Membrane lipid biosynthetic process 0.2912424905312649 0.1963800468816731 0.8443127124709824 1.0 0.9411393301503008 24 Q9Y2B2,Q8NBX0,O95470,Q96G23,O60762 5 +Regulation of dna dependent dna replication 0.2949893023255869 0.1949103636922206 0.845463120742187 1.0 0.9413567520972248 21 Q9UNS1,Q9BRX5,Q96S55,Q9BRT9,Q9UJZ1 5 +Nuclear transcribed mrna catabolic process nonsense mediated decay 0.3143760728217857 0.194771948888344 0.8455714832445915 1.0 0.9413567520972248 16 Q99729,P52298,P11940,Q9Y5S9 4 +Nucleoside monophosphate catabolic process 0.3272710326634475 0.1945399165193518 0.8457531438358061 1.0 0.9413567520972248 5 P49902 1 +Peptidyl lysine dimethylation 0.3484367205360308 0.1945358481879504 0.8457563290485866 1.0 0.9413567520972248 6 Q03164,Q12824 2 +Metal ion transport 0.2700064098361786 0.1941548626154509 0.846054624692957 1.0 0.9413567520972248 99 Q9HD20,Q99653,Q9H1K1,P21796,O00429,Q9HC07,Q9UJZ1,P02786,Q13586,Q8WWC4,Q12955,Q6P4Q7,O15173,O43865,Q13555,Q96PU5,P23634,P04899,Q9Y6M7,P50570,Q4KMQ2,P54652,Q06787,P27105,P05771,P28161,P07948,O75844,P46939,P35670 30 +Dna geometric change 0.2692157389221488 0.193979565830841 0.8461918821010144 1.0 0.9413567520972248 51 P12956,Q9BRX5,Q96S55,Q9BRT9,Q96RR1,P25205,P33991 7 +Positive regulation of peptidyl tyrosine phosphorylation 0.3257261632469487 0.1934492979111665 0.8466071103568793 1.0 0.9413567520972248 13 P07948,Q13432,Q92974 3 +Positive regulation of cation channel activity 0.3467022350755823 0.1934068563754127 0.8466403462010204 1.0 0.9413567520972248 7 Q13586,P28161 2 +Detection of stimulus 0.3254761280187648 0.1924988094105157 0.8473515004246379 1.0 0.9413567520972248 13 Q9UNS1,Q8WTV0 2 +Negative regulation of dephosphorylation 0.3447198783181729 0.1924778273248523 0.8473679344151306 1.0 0.9413567520972248 8 O95429 1 +Regulation of granulocyte chemotaxis 0.3445499063658609 0.1919284305867547 0.847798267037601 1.0 0.9415084704974052 8 O94813,Q00013 2 +Regulation of establishment of protein localization 0.2564439935418107 0.1911745297815699 0.8483888578666554 1.0 0.9418000407605648 132 Q99653,Q8NBM4,O95429,Q32P28,Q9Y5K6,O00429,P50402,P55786,O75312,P15311,Q9Y3D6,O00459,Q16822,Q7Z434,O00410,Q16836,Q12955,Q9NW64,P30040,O95817,Q99496,P41240,Q7Z3B4,O95563,O43464,Q6WKZ4,P27105,Q96DZ1,P53367,P35580,O95071,Q9Y385,P06493,P50416,Q8N183,P31751,Q14C86,P51572,Q9Y282,Q16850,P78371,O96028 42 +Hippocampus development 0.3192500192551148 0.1906906467763224 0.8487679670188466 1.0 0.9418000407605648 14 P07196,P46108,P23634 3 +T cell mediated immunity 0.3420410010153374 0.1902806262779597 0.8490892342929199 1.0 0.9418000407605648 9 O15400,P04439 2 +Negative regulation of cell activation 0.3021476312593852 0.1886806606951742 0.8503431098564471 1.0 0.9427013722206548 19 Q96J02,P09601 2 +Membrane docking 0.2896666613690801 0.1874715056022241 0.8512909628370369 1.0 0.9432627608963536 27 Q99653,P56545,O43865,Q6IQ22,O15400,Q13277,O60499,Q13190,P15311 9 +Myotube differentiation 0.3180589025117578 0.186024369326196 0.8524256509111594 1.0 0.944030480708454 14 P41440 1 +Pyrimidine nucleobase catabolic process 0.2812297734627871 0.185594282856924 0.8527629372928851 1.0 0.944176220826772 3 Q16555,Q9BPU6 2 +Regulation of glucose metabolic process 0.2882142992055735 0.1844738534940972 0.8536417370324338 1.0 0.944863302795672 22 Q13794,P31751,Q9BYT8,Q15118 4 +Positive regulation of sodium ion transport 0.3400491529994333 0.1837249393009669 0.854229243201174 1.0 0.944863302795672 9 Q12955,O43865,P50570 3 +Spinal cord development 0.3327466507106111 0.1817908035857653 0.8557469019412538 1.0 0.94540477412373 11 O95817,Q9UKA9,P07196,Q14203 4 +Golgi organization 0.2714091130603603 0.181622583914937 0.8558789242184095 1.0 0.94540477412373 46 P83436,P50570,Q14746,P06493,Q92538,O75396,O15027,Q9UP83,Q9P2W9,Q9Y2V7,Q13190,Q8NHH9,Q8TBA6,P40616 14 +Ear development 0.3005131699556631 0.1813003020990248 0.8561318689172035 1.0 0.9455212404823008 19 P42892,Q9Y6M7 2 +Response to interleukin 4 0.3410048622366334 0.1805948657344965 0.8566855861693927 1.0 0.9456382762689828 8 P49736,P08238,P49327,Q14145,P11802,P33993,P12268 7 +Positive regulation of potassium ion transport 0.3425853359773049 0.1805796247628899 0.8566975500250114 1.0 0.9456382762689828 7 P50570 1 +Regulation of cell death 0.2367603797796615 0.1804135187219724 0.8568279420546414 1.0 0.9456382762689828 317 P46379,O94813,Q9P0J0,O95429,Q9HBM6,Q9BUP3,Q9NS69,Q99720,Q99956,P61978,P21796,P11717,O15118,Q9HCL2,Q9Y4G8,P50897,P02786,Q9Y3D6,Q96K76,P17655,P23396,Q96TA2,Q15392,Q9UMX5,P45880,O95831,P04899,O95817,Q92974,Q96HY6,Q96J02,P16989,Q92879,Q6FI81,Q86XL3,P50570,Q4KMQ2,O43464,P09601,Q12981,Q13794,Q9NQX7,Q9NXR7,P07948,Q8N163,P31751,P51572,P07196,P78318 49 +Interleukin 6 production 0.336665977385601 0.1800001405295453 0.8571524578736582 1.0 0.9458335780633756 10 P17655,Q92974,Q08722 3 +Protein stabilization 0.2676977780774753 0.1795275677916172 0.8575234729855019 1.0 0.9460227288454052 71 P83436,P46379,O95429,Q32P28,P41440,O75718,Q9H2J4,O95817 8 +Muscle contraction 0.2792993272586345 0.1782282972485963 0.8585436874944992 1.0 0.9465165503150548 38 P46939,Q86U42,P67936,Q9Y5P4,P28289,Q96PU5,P23634,P14649,P28161 9 +Response to ionizing radiation 0.2838686838464455 0.1763736776899139 0.8600003826442182 1.0 0.9475081561961908 34 Q68E01,O75844,Q9BXW9,P50570,P12956,Q9H1E3,P62993,P38398,Q9NXR7 9 +Positive regulation of interleukin 2 production 0.3423611619123859 0.1761638536161129 0.8601652172764631 1.0 0.9475269020007095 6 Q9UJZ1,P23396 2 +Transcription elongation from rna polymerase ii promoter 0.2870535522856515 0.1758493288507058 0.8604123146049956 1.0 0.9476362434051584 29 Q9GZS3,P35269,O14776,Q8IXH7 4 +Positive regulation of cell killing 0.3418906088472313 0.1747688681771683 0.8612612514015312 1.0 0.94824538328475 6 O15400,P04439 2 +Negative regulation of epithelial cell migration 0.3258250954807201 0.1744065178165782 0.8615459923463828 1.0 0.94839598333167 12 O94813 1 +Protein targeting to lysosome 0.3383080706725877 0.1721348167571008 0.8633315414571094 1.0 0.9500041866077392 8 P20645,Q14108 2 +Negative regulation of amyloid fibril formation 0.320006790161182 0.1717936604375939 0.863599749666661 1.0 0.9500041866077392 5 O60925 1 +Regulation of amyloid fibril formation 0.320006790161182 0.1717936604375939 0.863599749666661 1.0 0.9500041866077392 5 O60925 1 +Positive regulation of filopodium assembly 0.319624352331604 0.1706257311557616 0.8645180640774515 1.0 0.9506880752678784 5 Q9H6U6,P11233,P60953,Q06787 4 +Establishment of mitotic spindle localization 0.335927367055774 0.1704086011541584 0.8646888083326489 1.0 0.950712737806566 9 O43264,Q9BXS6,P53350,Q14980,P05556,Q14203,Q7Z460,P43034 8 +Ventricular septum development 0.3389824438673396 0.1696134730301083 0.8653141261382138 1.0 0.9508613212717796 7 O94813 1 +Regulation of response to cytokine stimulus 0.3015109639133895 0.169455713192408 0.8654382042770807 1.0 0.9508613212717796 18 Q14166,O94813,Q9Y3Z3 3 +Intermembrane lipid transfer 0.3398807484741108 0.1688563381844983 0.8659096430374809 1.0 0.9508613212717796 6 Q9Y5P4 1 +Microtubule organizing center organization 0.2841350169235042 0.16820004070424 0.8664259089240194 1.0 0.9509290773006784 32 P53350,O94927,P38398,P06493,Q9H6D7,P52732 6 +Neurotransmitter reuptake 0.2984784719974038 0.1678395027589271 0.8667095445844888 1.0 0.9509290773006784 4 O14656,Q99808,P05556 3 +Response to sterol depletion 0.3383281092624 0.1676482333707296 0.8668600234260995 1.0 0.9509290773006784 7 P07948 1 +Nuclear envelope organization 0.2851703871965737 0.1676302654755919 0.8668741596949019 1.0 0.9509290773006784 30 Q96FZ7,O75844,Q86XL3,P20700,Q5JTV8,P53350,O94901,Q8N1F7,Q9ULX6,P50402,P05771 11 +Regulation of apoptotic signaling pathway 0.2692527919419536 0.1672737634203022 0.867154647026041 1.0 0.950970207442094 91 Q8N163,P16989,Q9P0J0,Q9HBM6,P23396,O43464,P51572,P09601,P61978,P45880,Q13794,Q9Y3D6,P04899,Q9NQX7,Q96K76 15 +Positive regulation of protein kinase b signaling 0.3105201771813139 0.1670932236909671 0.867296697770122 1.0 0.950970207442094 15 Q13641 1 +Attachment of spindle microtubules to kinetochore 0.3101284815166257 0.1655713625155049 0.868494285586876 1.0 0.9514536257551978 15 P14635,Q96EE3 2 +Trna processing 0.2766574374969621 0.1612641778791939 0.87188533584898 1.0 0.9543353834665104 38 Q08J23,Q99575,Q5KU26,Q5VV42 4 +Negative regulation of cell growth 0.2845535534566148 0.1609251322532029 0.8721523676048077 1.0 0.9543353834665104 28 Q8N163,Q9P0J0,O94813,P50897,Q8N0X7 5 +Regulation of mitophagy 0.3364863082379964 0.1590408893024879 0.873636658792937 1.0 0.9549814090830024 6 P21796 1 +Cellular response to sterol depletion 0.3359248461289251 0.1574381403255674 0.8748995566117401 1.0 0.9557099791890344 6 Q9BY44,O75477,Q6P1A2,P05198,O94905 5 +Multivesicular body organization 0.3347375243033066 0.1570102689341599 0.8752367550442992 1.0 0.9557181426344956 7 Q96FZ7,Q99816,Q8WUX9,O43633,Q8WUM4,Q9BRG1 6 +Positive regulation of hydrolase activity 0.2685685453628531 0.1569864388591897 0.875255535802447 1.0 0.9557181426344956 81 Q96HY6,P07948,Q9P0J0,Q9UL46,O43464,P31751,Q96F07,P51572,P46108,Q9Y4G8,Q13794,Q66K14,O95831,Q9Y3D6,P84095 15 +Regulation of gliogenesis 0.3295888653477684 0.1568610926271968 0.8753543237764623 1.0 0.9557181426344956 10 Q96G23 1 +Peptidyl tyrosine dephosphorylation 0.3248892053271603 0.1551790930949438 0.876680129915318 1.0 0.9564722212343358 11 Q13614,Q99956 2 +Regulation of phospholipase activity 0.3340625742278967 0.1550383649956545 0.8767910720706642 1.0 0.9564722212343358 7 P40616,P50897 2 +Viral budding 0.3346290897311276 0.1537619703541246 0.8777974204291157 1.0 0.9572442097568276 6 Q96FZ7,Q99816,Q8WUX9,O43633,Q8WUM4 5 +Midbody abscission 0.3346290897311275 0.1537619703541243 0.8777974204291159 1.0 0.9572442097568276 6 Q96FZ7,Q8WUX9,O43633,Q8WUM4,O95235 5 +Regulation of mononuclear cell migration 0.3069821101702935 0.1534944326192046 0.8780083804105008 1.0 0.9573113996311124 15 P07948,O94813,P46108,Q08722 4 +Response to endogenous stimulus 0.2436107569425934 0.1532089051966777 0.8782335352525112 1.0 0.957394040981054 258 P42785,O94813,O95429,O15118,Q15291,Q9Y4G8,Q96KQ7,P04114,Q969T9,Q92896,O00459,P48163,P17655,O15173,Q16836,Q6IQ22,Q9H1E3,P62993,Q15392,P35241,Q9UQB8,P23634,Q8N0X7,O95831,P04899,Q92974,Q96HY6,Q9UNS1,Q6IAA8,P08670,P50570,P09601,Q06481,O43823,Q8TBX8,P05771,P33527,P28161,P07948,O95071,O75844,P31751,P46108,Q9HCD5,P09960,Q05086,Q86X55,Q9NUQ7,P07196 49 +Regulation of protein containing complex assembly 0.2671578726985428 0.1484201438205431 0.882011203659627 1.0 0.960138475368504 93 O94813,Q13045,O95429,Q71SY5,P23396,Q16625,Q96F07,P28289,P36405,P62993,Q9UEY8,P45880,P35241,Q9UQB8,P02786,P35611 16 +Negative regulation of neuron death 0.2781784537494967 0.1483087134475554 0.8820991390710016 1.0 0.960138475368504 35 O43464,Q9UMX5,P09601,P50897 4 +Sphingolipid metabolic process 0.28157318277421 0.1462584199358013 0.8837173888969025 1.0 0.9613702179712572 29 O43464,Q9Y5P4,Q8NCC3,P50897,Q96G23 5 +Regulation of retinoic acid receptor signaling pathway 0.2913564260278338 0.1459548364812346 0.8839570417945641 1.0 0.9613702179712572 4 Q13573,A5YKK6,P56545 3 +Regulation of response to biotic stimulus 0.2601216131155962 0.1459249117947887 0.8839806653233371 1.0 0.9613702179712572 54 P07948,Q96J02,O75844,Q14166,Q7Z434,P12956,P46108,Q06481,Q9NZ08,Q9Y3Z3,P04439,Q8WXF1 12 +Positive regulation of response to dna damage stimulus 0.2740689774902235 0.1449423076429362 0.884756422446562 1.0 0.9617243798342314 38 Q9UNS1,Q8N163,P23396,Q06787,P51114,Q9NQ88,P38398,Q13794,Q7Z4V5,P18887,Q9NXR7 11 +Maintenance of protein location in cell 0.2955951975234727 0.1446805077294084 0.884963129790568 1.0 0.9617859718476672 18 P24390,O43731 2 +Anatomical structure formation involved in morphogenesis 0.2547284373363659 0.1424730802690071 0.8867063412755218 1.0 0.9627677681297264 143 Q13614,P42785,Q9H6E4,O94813,Q13045,P41440,Q9NR77,P09601,Q9NZ08,P23634 10 +Regulation of histone h3 k4 methylation 0.2980214360283707 0.1412000661926984 0.8877118937854183 1.0 0.9634665152665988 17 Q9GZS3,Q6W2J9,P38398,Q96KQ7,Q03164,P18615 6 +Negative regulation of peptidase activity 0.2768551505081001 0.1405116072449536 0.8882557822162163 1.0 0.9637304610707425 35 Q15392,P78318,Q96K76,Q92530 4 +Amyloid precursor protein metabolic process 0.2944406994266247 0.1399687078532828 0.8886847144764101 1.0 0.964032665390724 18 P07948,Q15392,Q9NQX7 3 +Receptor localization to synapse 0.3274669933947041 0.1395757562644974 0.8889951967851755 1.0 0.9640431756712864 8 O15400 1 +Positive regulation of mitotic cell cycle phase transition 0.2795286728027305 0.1391925563532416 0.8892979904151743 1.0 0.9641670859328764 31 Q96FF9,P35241,Q9UJX3,Q96DY7,P14635 5 +Regulation of ubiquitin dependent protein catabolic process 0.2578653612335345 0.1370131539635029 0.8910203978093234 1.0 0.9649338004345044 55 Q96HY6,Q8N163,Q8WU17,P46379,Q9Y5A7,P53350,P51572,Q05086,O95816,Q96JB5,Q9H2J4,O15372 12 +Regulation of histone h4 acetylation 0.3285759392399041 0.1370126773547528 0.8910207745353871 1.0 0.9649338004345044 6 O75844,Q12824 2 +Positive regulation of viral life cycle 0.3079663212435213 0.1364865899081183 0.8914366250484838 1.0 0.9650084831379314 5 Q06787,Q99816,Q9UN37,P52292 4 +Regulation of viral entry into host cell 0.3079663212435209 0.1364865899081172 0.8914366250484846 1.0 0.9650084831379314 5 Q14258,Q92692,P14373,O60493 4 +Positive regulation of hexokinase activity 0.2660194174757326 0.1359927283998043 0.8918270294564448 1.0 0.9650084831379314 3 Q9NQ88,P49792 2 +Regulation of hexokinase activity 0.2660194174757326 0.1359927283998043 0.8918270294564448 1.0 0.9650084831379314 3 Q9NQ88,P49792 2 +Ncrna export from nucleus 0.3258766139909186 0.1349992765322187 0.8926124463387974 1.0 0.9654054196477142 8 P52298 1 +Intermediate filament based process 0.3042844937641326 0.1346708485430583 0.892872122676023 1.0 0.9654706994523122 14 Q96RT1,P08670 2 +Positive regulation of cell cycle phase transition 0.2694283932306316 0.1342459342002145 0.8932081043822824 1.0 0.9656710995261308 40 Q96HY6,Q96FF9,P35241,Q9UJX3,Q96DY7,P14635 6 +Positive regulation of histone h3 k4 methylation 0.3084356482299368 0.1312483677576563 0.8955788349170768 1.0 0.9675756098238898 13 Q9GZS3,Q03164,P38398,P18615 4 +Response to vitamin d 0.3262978476757981 0.1308922352247145 0.895860557228721 1.0 0.9675756098238898 6 Q15648,Q13573,Q8TB36 3 +Fibroblast proliferation 0.3007661282062091 0.1304232396548885 0.896231581038768 1.0 0.9676342318441136 15 P14635,O75844,Q71SY5 3 +Iron ion transmembrane transport 0.2637540453074481 0.129137597684056 0.8972487724214275 1.0 0.967787632929323 3 Q04656,Q9H1K1 2 +Regulation of cytosolic calcium ion concentration 0.2766024443488958 0.1290987033861925 0.8972795479717577 1.0 0.967787632929323 22 P07948,P51572,Q9Y3D6,P23634 4 +Protein insertion into er membrane by stop transfer membrane anchor sequence 0.3253190925755315 0.128293755360619 0.8979165067695953 1.0 0.9680905009384456 6 Q9NPA0 1 +Cell volume homeostasis 0.324386422648392 0.1277551680190562 0.8983427299819426 1.0 0.9682826465754586 7 P51790 1 +Glycerophospholipid biosynthetic process 0.2647352547654942 0.1266826009723561 0.8991916172887937 1.0 0.9687089524069188 43 Q13614,O00459,Q9Y2B2,P17655,Q9HCL2,Q10713,Q9NPH0,Q8TBX8,O60762 9 +Autophagosome maturation 0.2968164468154653 0.1254261419229867 0.9001861932689785 1.0 0.9693932336713448 16 Q9H267,Q8NHS3 2 +Cell morphogenesis 0.2545074113155367 0.1239927309031919 0.901321030547518 1.0 0.9700248162877084 153 Q9Y4F1,O94813,Q16181,Q71RC2,Q9Y4G8,P42892,P84095,Q13641,P41440,Q96AX1,Q96PU5,P35241,Q9UQB8,Q8N0X7,Q92974,O75400,P50570,Q9Y5P4,Q96F07,Q15375,Q06481,P35580,O75844,Q92766,P46108,Q05086,P07196 27 +Defense response 0.2548709570376907 0.1217107968553146 0.9031280621596558 1.0 0.9714802615276712 188 P42785,P12956,Q9HCL2,Q9NZ08,P02786,Q9Y5A7,P07437,P60602,Q96S55,P28070,Q5KU26,Q96J02,Q92879,P08670,Q08722,P09601,Q06481,O43823,Q13794,Q96EE3,P07948,Q9BXW9,Q03518 23 +Regulation of growth 0.2566828460478329 0.120698769956053 0.90392963330659 1.0 0.9720788933960404 115 O94813,Q9P0J0,Q9HBM6,Q99956,Q9HCL2,P50897,P02786,Q5BJF2,Q96K76,Q96PU5,O95470,P80723,Q8N0X7,Q9BTE7,Q96J02,P16989,Q6IAA8,P50570,O43464,Q15375,Q5PSV4,Q8N163 22 +Amyloid precursor protein catabolic process 0.3002647827555855 0.1206252405575197 0.903987875746302 1.0 0.9720788933960404 14 Q96S59,P07948,O75298,Q15392,Q96P70 5 +Rna destabilization 0.2732555092706203 0.1196908362388215 0.9047280597939876 1.0 0.9722224414550644 35 Q92879,Q96C86,P52758,Q9HCE1,Q9HBH5,P67809,Q92900,O60506,O75534,Q969T7,Q96B26,Q9NZI8,Q9NQT5,Q13868,P11940,Q9H2U1 16 +Peptidyl lysine acetylation 0.2609842636294488 0.118015109078125 0.9060556862313438 1.0 0.9726737202209133 49 Q9NRF9,O75844,P46379,Q9UKN8,O75448,Q86UY6,Q12824,Q969T9,Q03164,Q9BX68 10 +Regulation of immunoglobulin production 0.2972964302189961 0.1180115975846447 0.9060584685552376 1.0 0.9726737202209133 15 P02786,O96028,Q9NQT5 3 +Response to axon injury 0.3123408181693316 0.1155603838413016 0.9080009616024108 1.0 0.9741928237857138 11 P07948,Q96G23,P07196,P06493 4 +Platelet morphogenesis 0.2995956645599132 0.1137697484537842 0.9094203200879352 1.0 0.9744875044740328 5 Q96AX1,P35579 2 +Regulation of cyclin dependent protein kinase activity 0.2874670664727655 0.1123900397128255 0.910514152449052 1.0 0.9754965263577507 18 P53350,O00410,P42771,Q96JB5,Q9P287,P14635 6 +Regulation of protein autophosphorylation 0.3182951002477 0.1115451505611694 0.91118406399593 1.0 0.975994621425886 7 Q15375,Q99653 2 +Positive regulation of autophagy of mitochondrion 0.2985751295336765 0.1111052565311308 0.9115328804436222 1.0 0.975994621425886 5 P12235,P05141,P27544,P21796 4 +Peptidyl arginine modification 0.2985751295336764 0.1111052565311302 0.9115328804436228 1.0 0.975994621425886 5 O60678,Q86X55,Q99873,O14744 4 +Mrna splice site selection 0.2804201646021192 0.1110170526794329 0.9116028242384928 1.0 0.975994621425886 20 O95319,Q92879,Q15637,O75494,Q9UKA9,Q9NQ29,Q13247 7 +Regulation of ubiquitin protein transferase activity 0.2732146000159067 0.1108435964886389 0.9117403733382536 1.0 0.975994621425886 23 P53350,O95816,O60566,Q16763,Q9BTE7 5 +Nadp metabolic process 0.2927423035066909 0.1105867209565504 0.9119440780345828 1.0 0.9760149670559258 16 P48735 1 +Multi organism reproductive process 0.2522588000588447 0.1103665186715597 0.9121187051103874 1.0 0.9760149670559258 140 P46379,Q16181,Q8NB78,P11717,P04114,Q08J23,Q15102,P17655,P41440,O75718,Q9P0K7,P45880,O95470,P23634,P16989,Q92879,P50570,O94901,Q9UIQ6,Q9BXW9,P51572,Q05086 22 +Regulation of proteasomal protein catabolic process 0.255766974173307 0.1085946792274474 0.9135239811574416 1.0 0.976762088276764 64 Q96HY6,Q8N163,P46379,Q9UL46,Q9Y5A7,P60520,Q92530 7 +Anaphase promoting complex dependent catabolic process 0.3130971843260295 0.1071374320557686 0.914679951568558 1.0 0.977671917551185 10 Q9UJX3,Q16763 2 +Phosphatidylinositol phosphate biosynthetic process 0.3164197562228937 0.1067076148629505 0.915020941316466 1.0 0.977762135891094 7 Q8TBX8 1 +Positive regulation of production of molecular mediator of immune response 0.2828022404418421 0.1066464951758556 0.915069431078108 1.0 0.977762135891094 19 Q9NQT5,Q7Z434,O96028,P02786,P04439 5 +Regulation of peptidyl lysine acetylation 0.2792205462756487 0.1061189993305515 0.915487936975076 1.0 0.9778794208060828 20 O75844,Q12824,Q969T9,Q03164,Q9BX68 5 +T cell receptor signaling pathway 0.2938425249253965 0.1059960765721642 0.9155854650928228 1.0 0.9778794208060828 15 P23396,Q07666,Q9UJZ1,P15311,P04439 5 +Pore complex assembly 0.3051206084947189 0.1059312977833859 0.9156368617282542 1.0 0.9778794208060828 12 P57740,Q4KMQ2,P55196 3 +Lymphocyte apoptotic process 0.2883878865452086 0.1045967070854737 0.9166958277388804 1.0 0.9786929752239114 17 P24390,Q9HCL2 2 +Cerebral cortex development 0.2727417605292145 0.1024721455138251 0.9183819211034948 1.0 0.9795067311593176 26 P46108,O94813,Q8WXH0,P07196 4 +Negative regulation of response to biotic stimulus 0.2928099912332762 0.1024707028081139 0.9183830661883774 1.0 0.9795067311593176 15 Q14166,Q96J02,P46108,P04439 4 +Leukocyte differentiation 0.2510100683408111 0.1011635625710134 0.9194206211413832 1.0 0.980018587960768 57 P07948,Q9BXW9,P24390,P12956,P0CG08,O43290,P02786 7 +Endothelial cell development 0.2923343525051201 0.1008571262424524 0.9196638778002522 1.0 0.980018587960768 15 P55196,O60568,P35241,Q9Y4G8,P35611 5 +Response to amino acid starvation 0.3070626684920447 0.0999962987275279 0.9203472639055592 1.0 0.9802967699625514 11 P05198,Q96EE3,Q9P2J5 3 +Specification of symmetry 0.3132491091674733 0.0978096965344699 0.9220834075852063 1.0 0.9813641717575337 6 Q8TD19,Q15363,P35222,Q10567,Q9NVR5 5 +Cell cycle dna replication 0.2799434381349001 0.0955567152571085 0.9238726440412984 1.0 0.9829084893451824 19 O75844,Q92900,Q9BY42,Q14566,Q9BRX5,O75312,P25205,P33991 8 +Pyrimidine nucleobase biosynthetic process 0.3119533527696762 0.0947108428212527 0.9245445053699476 1.0 0.9832968772890932 6 Q9NRF8,P17812,P30085,P42345,P27708 5 +Negative regulation of cellular component organization 0.2527275277303005 0.0939265815960057 0.925167478116632 1.0 0.983796206822762 155 Q13614,O94813,P29372,P28289,O75396,Q9Y4G8,Q96KQ7,Q96DY7,P02786,Q13045,Q9NR77,Q13432,P45880,O00264,P38398,P35241,P07910,Q8N0X7,P18887,Q92974,P35611,P08670,P50570,Q15375,Q9NUQ9,P14635,O60925,Q9NQX7,P53350,Q05086,Q9NQ88,Q9UEY8,Q86X55,Q96G23 34 +Cristae formation 0.3094819122643634 0.093406935942529 0.925580280525268 1.0 0.9839556009018604 9 Q5XKP0 1 +Microtubule nucleation 0.3047373142299506 0.0933514244148624 0.9256243796315472 1.0 0.9839556009018604 11 Q96S59,Q96P70,Q9BSJ2,Q14203 4 +Regulation of system process 0.2575263651493014 0.093065121535033 0.9258518261265049 1.0 0.9840341909253684 49 Q13614,P42892,Q13555,Q9UQB8 4 +Protein localization to vacuole 0.2896568243497535 0.091896818872048 0.9267800189407104 1.0 0.9846259281565556 15 Q96RL7,P20645,Q14108 3 +Inner cell mass cell proliferation 0.3104459673137685 0.0917843235792901 0.9268693994534564 1.0 0.9846259281565556 7 Q9BRT9,Q9Y3A5 2 +Trna modification 0.2718599350219561 0.091115196573102 0.9274010577517192 1.0 0.9850274697909726 21 Q9H974,Q08J23,O75648,Q5VV42 4 +Regulation of biological process involved in symbiotic interaction 0.3083657587548657 0.0904916420292193 0.927896535399474 1.0 0.9852809800826522 9 Q14258,Q92692,Q9BTY2,P06756,Q9UPT5,P14373,Q96KP1,O60493 8 +Negative regulation of innate immune response 0.3092879022051491 0.0904264131979051 0.9279483679737476 1.0 0.9852809800826522 8 Q14166,P46108,P04439 3 +Nucleotide sugar metabolic process 0.3097280669406865 0.0900410715029763 0.9282545770232662 1.0 0.9852809800826522 7 Q9NR45,O60762 2 +Regulation of fibroblast migration 0.3087671496668131 0.0891223943237515 0.9289846401137398 1.0 0.9857294393526026 8 O95429 1 +Nuclear membrane organization 0.2672484327570357 0.0881096417752708 0.9297895331578272 1.0 0.9864202097884264 22 Q96FZ7,Q86XL3,Q5JTV8,P53350,Q9ULX6,P50402,P05771 7 +Positive regulation of ion transmembrane transport 0.2685813724575517 0.0876434593596333 0.9301600594853658 1.0 0.9864867606388475 24 Q4KMQ2,P50570,Q13586,Q12955,P54652,P08183,P28161 7 +Vascular associated smooth muscle cell proliferation 0.3026180021081181 0.0874094609296112 0.9303460494298812 1.0 0.9865207902143156 11 P09601 1 +5s class rrna transcription by rna polymerase iii 0.288746376384129 0.0866320333706989 0.9309640026660972 1.0 0.986849554670032 5 Q9Y5Q8 1 +Muscle tissue development 0.257069605441221 0.0859678139163721 0.9314920032497324 1.0 0.9870827807622392 48 P16989,P41440,Q9BYT8,Q9NQ29,Q9Y5Q8 5 +Positive regulation of map kinase activity 0.3077066130953038 0.0851905942975504 0.9321098680615464 1.0 0.9874712602612458 7 P18031,P30040,P23396,P41240 4 +Positive regulation of proteolysis 0.2618759016843348 0.084754778624646 0.9324563455493188 1.0 0.9876148669813508 83 Q96HY6,P07948,P46379,Q9P0J0,Q9UL46,Q9Y5A7,P23396,O43464,Q96A26,Q96F07,P51572,Q13794,Q96JB5,O95831,Q9Y3D6,O43847 16 +Hormone transport 0.2683060302980357 0.0825177447309955 0.934235008199762 1.0 0.9886224541649382 32 O95563,P50416,Q13555,Q6WKZ4 4 +Body morphogenesis 0.3064209492712586 0.082150394894724 0.9345271191856206 1.0 0.9886224541649382 7 O95470 1 +Cellular nitrogen compound catabolic process 0.2522249995737833 0.0818287694313967 0.9347828780868048 1.0 0.9886224541649382 159 P11940,Q96C86,Q9Y3B2,Q13126,Q5RKV6,Q7L8L6,Q6NZY4,P30519,Q96B26,Q9Y3Z3,Q9H773,P98175,Q9NQT5,Q08J23,Q99729,Q9HCE1,Q9Y4Y9,P67809,Q9BQ61,Q6P6C2,P62312,P07910,O95831,Q99575,Q9UK45,P16989,Q15717,Q14011,P08670,Q92879,Q13310,P09601,Q969T7,Q92804,P51114,P49902,Q9BPU6,Q9Y5S9,Q9NRN7,P33527,Q8IYS1,Q9H814,P53004,P52298,O60506,O43598 46 +Negative regulation of intracellular signal transduction 0.2611007130243114 0.0816186484225838 0.9349499714739244 1.0 0.9886224541649382 96 P07948,Q8N163,P16989,O94813,Q9P0J0,Q96J02,Q9HBM6,O00459,O43464,Q99956,P45880,Q10713,P23634,Q96P70,Q96RT1,Q92974,Q96K76,P78318 18 +Epithelial cell proliferation 0.2629717617888026 0.078544346684584 0.9373950556039652 1.0 0.990880987206698 38 Q92766,P09601,Q8WTV0 3 +Multicellular organismal movement 0.3046383713782638 0.0779928625488328 0.9378337305601732 1.0 0.991136441101142 7 P28161 1 +Vasculature development 0.2614824651150753 0.0776551472327278 0.9381023736339622 1.0 0.991136441101142 88 P42785,O94813,Q9H6E4,P09601,Q9NZ08,Q9Y4G8,P23634,Q96AY3 8 +Regulation of cellular component biogenesis 0.2513026934989834 0.0775424713138344 0.938192005740082 1.0 0.991136441101142 201 Q9Y4F1,O94813,O95429,Q16181,Q96JM7,P28289,O75396,P36405,Q8NEY8,Q9Y4G8,Q96KQ7,P02786,P84095,Q13641,Q13045,P23396,P41440,Q16625,P62993,P45880,P38398,Q9UQB8,P35241,Q8WXH0,P35611,Q15047,P50570,Q08722,Q96F07,Q15375,P51114,Q9P2W9,Q8TBX8,Q9NUQ9,Q71SY5,Q9NUL3,Q9UEY8,Q66K14 38 +Positive regulation of necrotic cell death 0.2657818064098347 0.0774630126653864 0.9382552144464478 1.0 0.991136441101142 4 P04637,P00403,Q9NZI8 3 +Alcohol biosynthetic process 0.2630494887986709 0.0729946289644284 0.9418103915759504 1.0 0.9942365958501056 37 P48449,P61457,Q15392,Q16850,P04114,Q15800 6 +Cellular component disassembly 0.2503836888576048 0.0676862542012446 0.9460353917737544 1.0 0.9980393122563802 148 Q96FZ7,P61221,Q07866,P29372,P21796,P28289,Q14203,Q96E11,Q9Y3D6,Q8NHS3,Q13045,P41440,Q96AX1,P35241,Q13190,P13798,O95831,Q92974,P35611,Q96HY6,O43464,O75381,Q96JB5,Q12824,P05771,O75844,Q86VR2,P53350,P60520,Q92538,Q9ULX6,Q9NQ88,Q9UEY8,P06493,Q9H267 35 +C4 dicarboxylate transport 0.2976459615929514 0.0661560262310267 0.947253606021599 1.0 0.9990342470858324 10 Q8TDW0,Q15758,O75746,Q9UJS0 4 +Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.2988654781199503 0.0654526051703453 0.9478136409666706 1.0 0.9994218520474352 8 Q9Y4L1,O60313,P18031,O95881,P55061,O76024,O00330 7 +Mitotic metaphase plate congression 0.2646250188364122 0.064253174331878 0.9487686378347642 1.0 1.0 27 P14635,Q96EE3,Q13561,Q53HL2,Q96DB5 5 +Glycoprotein biosynthetic process 0.2459463650027353 0.062366164383048 0.9502712393977476 1.0 1.0 59 O60476,Q86YN1,O60502,O15118,Q9HC07,Q8NCH0,Q9NQX7,O60762 8 +Antiviral innate immune response 0.2778453362825088 0.062037350945011 0.9505330875190076 1.0 1.0 5 Q9NVI7,Q92667,P35232 3 +Regulation of carbohydrate metabolic process 0.2637770846213116 0.0618435613816504 0.9506874128913696 1.0 1.0 33 Q15118,P31751,Q9BYT8,Q13794,Q14108 5 +Regulation of small molecule metabolic process 0.2510545054389637 0.0615926190398576 0.9508872549369034 1.0 1.0 52 P49748,Q15118,P50416,P31751,Q92520,Q9BYT8,P23634,Q13794,P04114 9 +Lung epithelium development 0.2776006200461572 0.0615161941244963 0.9509481177846376 1.0 1.0 5 P09960,Q13247 2 +Response to lipid 0.2481186137535534 0.061271801826653 0.9511427474781686 1.0 1.0 134 O94813,Q9P0J0,Q13126,Q86U42,P11717,O15118,P04114,P02786,P17655,O15173,O95831,Q96HY6,P08670,O43464,O43823,Q8WTV0,P07948,P50416,Q05086,Q86X55,Q9NUQ7,Q96RT1,P07196 23 +Regulation of adaptive immune response 0.2705660494378241 0.0611619296404292 0.9512302486898734 1.0 1.0 19 Q9NQT5,O15400,O96028,Q9NUQ9,P02786,P04439 6 +Regulation of mitotic spindle assembly 0.2963683527885885 0.0609296296480952 0.9514152522295504 1.0 1.0 9 P0DMV9,Q96FZ7,Q8WUX9,P53350,O43633,P12270,Q9Y295,Q8WUM4 8 +Electron transport chain 0.2555511632763995 0.0598466028106831 0.9522778083928758 1.0 1.0 72 P48163,Q9P0J0,Q6FI81,Q7KZN9,O95182,O43819,P51970,P14635,P06493,P00403,O75380,P21912,O43678,Q9Y375,P03886,P13073,O43676,O96000 18 +Positive regulation of sodium ion transmembrane transporter activity 0.2963829132029444 0.059616876959097 0.9524607764073278 1.0 1.0 7 Q12955,P50570 2 +Replication born double strand break repair via sister chromatid exchange 0.2372168284789693 0.0595826534340703 0.9524880343745956 1.0 1.0 3 P18887,O60216 2 +Dendritic transport 0.2960803368966599 0.0595318605843882 0.9525284893931624 1.0 1.0 6 Q00577,P33176,Q14254,P23246,Q9NUL3 5 +Oxidative phosphorylation 0.2543313322346946 0.0592147681086582 0.9527810470334 1.0 1.0 70 Q7KZN9,O95182,P00846,P14635,Q9Y375,P03886,P13073,P14406,O96000 9 +Cellular response to interleukin 1 0.2959376703501975 0.058865711756105 0.9530590687269872 1.0 1.0 8 Q86Y07,P38159,Q92900,Q08722 4 +Positive regulation of sodium ion transmembrane transport 0.2951112522484247 0.057040637024408 0.9545128241553628 1.0 1.0 8 Q12955,P50570 2 +Regulation of protein deacetylation 0.2783101438625623 0.0562858514965343 0.9551140898364688 1.0 1.0 15 Q8N163,O43823,Q9ULX6 3 +Biological adhesion 0.250023821750677 0.0562390734628228 0.9551513542810076 1.0 1.0 152 O95429,Q9HCL2,P02786,P49366,Q13641,P41440,Q53GQ0,Q8WWI1,P35241,Q9UQB8,Q96J02,P50570,Q08722,Q96F07,Q9UM22,Q8WTV0,P07948,P30825,Q92766,P46108,Q96RT1 21 +Supramolecular fiber organization 0.2500626354450359 0.0554627229620017 0.9557698269832444 1.0 1.0 153 O94813,O95429,Q13576,P29372,P28289,P36405,Q96AY3,P84095,Q92791,Q13045,P23396,P67936,Q16625,O75718,P62993,P49006,P35241,Q9UQB8,P13674,Q92974,P35611,P08670,Q08722,Q96F07,Q03001,P53367,O60925,Q9BSJ2,Q9UEY8,Q6WCQ1,Q96P70,P07196 32 +Negative regulation of map kinase activity 0.2937534538304255 0.0540682526066405 0.9568807859838732 1.0 1.0 7 P07948 1 +Regulation of circadian rhythm 0.2608657512133134 0.052354585817954 0.9582461597239078 1.0 1.0 25 Q05086,Q9UNS1 2 +Retinoic acid receptor signaling pathway 0.2915451895043697 0.0504315173075277 0.959778521153534 1.0 1.0 6 A5YKK6,P56545,Q13573,O43707,P46109 5 +Negative regulation of peptidyl lysine acetylation 0.2912635416969694 0.049880315215353 0.960217763956507 1.0 1.0 6 Q9BX68 1 +Regulation of exit from mitosis 0.290573372206022 0.0485365076923126 0.9612886697841604 1.0 1.0 6 O43264,Q9UJX2,Q96FF9,Q9NQW6,Q99623 5 +Maintenance of protein localization in organelle 0.2755681253115392 0.0482629009435795 0.9615067208386816 1.0 1.0 15 O43731 1 +Regulation of phosphatase activity 0.2868164300444448 0.0465914673903478 0.962838832682767 1.0 1.0 11 P04899,O95429 2 +Protection from non homologous end joining at telomere 0.2508902557461916 0.0451016797711045 0.9640262625230268 1.0 1.0 4 P18887,Q9UBB9,Q15554 3 +Microtubule polymerization or depolymerization 0.2599064667690313 0.0449627700546119 0.9641369841179052 1.0 1.0 34 Q96S59,Q8IX90,P23396,Q16625,P29372,Q9BSJ2,Q14203,P36405,Q96P70,Q92974,P36404,Q13526 12 +Insulin secretion 0.258127993576514 0.0442827882707723 0.9646789911855328 1.0 1.0 24 O95563,Q13555 2 +Positive regulation of lipase activity 0.2882048095875086 0.0439991952982476 0.9649050453068037 1.0 1.0 6 P35232,P40616,Q14344 3 +Divalent inorganic cation homeostasis 0.2446633985266441 0.041753504747085 0.9666952004996074 1.0 1.0 56 P07948,Q9HD20,Q13586,Q14344,Q96TC7,P35670,Q8WWC4,P51572,Q6P4Q7,P05771,Q9HC07,P23634,Q9UJZ1,Q9Y3D6,P28161 15 +Mrna cleavage involved in mrna processing 0.2870300487247404 0.0412531747829969 0.9670940623759106 1.0 1.0 10 O95639,P52298,Q6UN15 3 +Bone cell development 0.2665117187949821 0.0393269364545161 0.9686297310387476 1.0 1.0 5 Q15904,Q8IZP0 2 +Dendritic cell chemotaxis 0.2473292327614029 0.0381873133955308 0.969538335962764 1.0 1.0 4 P27797,P09429,Q4KMQ2 3 +Regulation of production of small rna involved in gene silencing by rna 0.2658678756476661 0.0381240155604169 0.9695888035779928 1.0 1.0 5 P17844,O75844,P04637,O75376 4 +Pigment granule maturation 0.247005503399154 0.0375743832498664 0.9700270326995716 1.0 1.0 4 Q9BXS5,Q13637,O43747 3 +Pigment accumulation 0.247005503399154 0.0375743832498664 0.9700270326995716 1.0 1.0 4 Q9BXS5,Q13637,O43747 3 +Negative regulation of signaling 0.2497845761615937 0.0366242354478971 0.9707846193977896 1.0 1.0 186 Q13614,O94813,Q9P0J0,Q8NBM4,Q9HBM6,Q99956,P50402,Q96K76,Q92896,O00459,Q13641,P45880,P23634,Q9NPR9,Q8N0X7,P04899,Q92974,Q96HY6,Q96J02,P16989,P50570,Q08722,O43464,P09601,Q6WKZ4,Q9NWT1,Q96JB5,Q8TBX8,P05771,P07948,Q8N163,Q14166,Q9HCD5,Q9NUL3,Q10713,Q96P70,Q96RT1,P78318 38 +Trna transcription 0.2841802802505037 0.0365534862379728 0.970841031326838 1.0 1.0 6 Q9Y5Q8 1 +Regulation of b cell activation 0.2696233376450291 0.0359768185688215 0.9713008430876536 1.0 1.0 16 P07948,P02786,O96028,Q9NQT5 4 +Regulation of response to external stimulus 0.2521611983318209 0.0358799058899626 0.9713781183264688 1.0 1.0 112 O94813,P12956,Q00013,Q9NZ08,Q9Y3Z3,P80303,P60900,Q13641,Q9UMX5,P28070,Q96J02,Q92879,Q4KMQ2,Q08722,Q06481,P33527,P07948,Q9BXW9,O75844,Q14166,P46108,P04439,Q96G23 23 +Dicarboxylic acid metabolic process 0.2503371404967884 0.0353870092603454 0.971771143333678 1.0 1.0 43 P48163,Q9UBQ7,P48735,Q9H9P8,P41440,P21912,Q8TD30,O14734,Q9NRN7 9 +Pyrimidine ribonucleoside triphosphate biosynthetic process 0.262305699481863 0.0316368980019524 0.9747616177574394 1.0 1.0 5 O75414,P27708,Q9NRF8,P17812 4 +Positive regulation of interleukin 6 production 0.2811748841976166 0.031209115367323 0.975102770444812 1.0 1.0 6 Q92974 1 +Regulation of protein acetylation 0.2526101123774766 0.0309533837591507 0.9753067162120316 1.0 1.0 22 O75844,Q12824,Q969T9,Q03164,Q9BX68 5 +Mitochondrial fission 0.2741277276993991 0.0308735398575489 0.9753703919954764 1.0 1.0 13 Q9UDX5,Q8TB36,O60313,O00429,Q9NUQ9,Q9Y3D6 6 +Positive regulation of substrate adhesion dependent cell spreading 0.2696340012311276 0.0285946590338548 0.9771878718177938 1.0 1.0 14 Q92766,P50570 2 +Regulation of protein tyrosine kinase activity 0.2799874384144993 0.0258658394868365 0.9793643470654576 1.0 1.0 9 Q96FZ7,Q13432 2 +Regulation of gene silencing by rna 0.2667316439246264 0.0239751018119494 0.9808724688731584 1.0 1.0 15 Q08211,O75844,Q15717,P17844,P55265,P40763,Q06787,Q9HAV4,P04637,P51114,O75376,Q04637,P26196,Q01085 14 +Response to camp 0.2784776795230331 0.0229424497985325 0.9816961792538276 1.0 1.0 9 Q9Y4G8 1 +Positive regulation of inflammatory response 0.2666450146151421 0.0210818916539535 0.9831803300522944 1.0 1.0 14 Q08211,P01130,Q15046,P51809,Q08722,P39019,P53634,P30046,Q9NZI8,Q53EL6,Q99497,Q99735,P33527 13 +Intraciliary transport 0.2558290155440393 0.0205667267994668 0.9835912830164956 1.0 1.0 5 A0AVF1,Q9UIS9,P36405,Q8WYA0 4 +Positive regulation of protein import 0.2600307773067402 0.0194875204570328 0.9844521923867506 1.0 1.0 18 O00459,O95071,O14737,Q7Z434,O00410,Q9NW64,O75312,P06493,O95817 9 +Regulation of protein polyubiquitination 0.272845106934556 0.0151666619618096 0.9878992185025596 1.0 1.0 7 P61088,O95071,O75150,Q14669,O00571,Q13309 6 +Negative regulation of apoptotic signaling pathway 0.2437416927774298 0.0143604959206551 0.9885423758266718 1.0 1.0 63 Q8N163,P16989,Q9P0J0,Q9HBM6,O43464,P09601,P45880,P04899,Q96K76 9 +Protein k48 linked deubiquitination 0.2729335494327499 0.0136747022695332 0.9890895062257674 1.0 1.0 8 Q93008,O94966,P45974,Q9H8M7,Q93009,Q99497,Q99496 7 +Protein acetylation 0.2423895838710402 0.0114665346848604 0.990851229491698 1.0 1.0 54 Q9NRF9,O75844,P46379,Q9UKN8,O75448,Q86UY6,Q12824,Q969T9,Q03164,Q9BX68 10 +Regulation of proteasomal ubiquitin dependent protein catabolic process 0.2462844270416137 0.0114150820775554 0.9908922800459908 1.0 1.0 45 Q96HY6,Q8N163,P46379,Q9Y5A7 4 +Positive regulation of mitochondrion organization 0.2467622899480647 0.0106101630242321 0.9915344735708906 1.0 1.0 22 O43464,Q13794,Q9Y3D6,P21796 4 +Demethylation 0.2618839447646386 0.0096609976623887 0.9922917590313662 1.0 1.0 14 Q9H6W3,Q16850 2 +Protein depolymerization 0.2507967415286866 0.009088749213284 0.9927483271636924 1.0 1.0 37 Q13045,P29372,P28289,Q9UEY8,P35241,Q92974 6 +Dendritic cell migration 0.2474093264248679 0.0075488926136859 0.9939769123374932 1.0 1.0 5 P27797,P60953,P09429,Q4KMQ2 4 +Neurotransmitter receptor transport 0.2470854922279772 0.0070786526608025 0.994352099497562 1.0 1.0 5 Q96QK1,Q13277,P61006,Q14160 4 +Organelle inheritance 0.2660298215869663 0.0070453945280478 0.9943786349865072 1.0 1.0 6 Q13190,Q92538 2 +P body assembly 0.2670123136746669 0.0059448652305825 0.9952567117555732 1.0 1.0 7 A5YKK6,Q9HBH5,P62310,Q9Y4Z0,P26196,Q96F86 6 +Regulation of spindle assembly 0.2673588578844901 0.0048795074395886 0.9961067317991574 1.0 1.0 11 P0DMV9,Q96FZ7,Q00839,Q8WUX9,P53350,O43633,P12270,Q9Y295,Q14980,Q8WUM4 10 +Protein k11 linked ubiquitination 0.2684366249802946 0.0048086393276383 0.9961632757081174 1.0 1.0 9 Q16763 1 +Positive regulation of interleukin 8 production 0.2660401814646801 0.0044754858059619 0.9964290908942036 1.0 1.0 7 P0DMV9,Q7Z434,P09429,P40763,P62820,Q99497 6 +Positive regulation of b cell activation 0.2685423128306745 0.0042629274099361 0.9965986863375488 1.0 1.0 10 P02786,O96028,Q9NQT5 3 +Regulation of mitotic cell cycle phase transition 0.2526151253590455 0.0041924667407064 0.9966549053152444 1.0 1.0 79 Q9UL46,Q13564,Q6NUQ1,Q96DY7,Q96K76,P42771,P38398,P35241,Q68E01,Q9NYL9,Q06481,Q9UJX3,Q96JB5,P14635,Q9NXR7,P53350,Q96FF9,Q9Y619,P31350,P06493,O60566 21 +Ribosomal small subunit export from nucleus 0.2633624878522801 0.0032589640114008 0.997399727533941 1.0 1.0 6 O14980,Q86U38,Q99567,P62826,P62841 5 +Positive regulation of posttranscriptional gene silencing 0.2663854639844221 0.0030396646337899 0.9975747022534622 1.0 1.0 11 Q08211,P17844,P40763,Q06787,Q9HAV4,P04637,P51114,Q04637,P26196,Q01085 10 +Myeloid leukocyte activation 0.2539376151812463 0.0023824669806245 0.998099068177866 1.0 1.0 18 P09601 1 +Golgi vesicle budding 0.2425518134715004 0.0007275695454417 0.9994194835439985 1.0 1.0 5 Q9BVK6,Q92538,P49755,Q15363 4 +Regulation of t cell receptor signaling pathway 0.242275820868652 0.0003548243257431 0.9997168911546328 1.0 1.0 5 P23396 1 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ad09de023a8df9763b9e765c3f4917f6fb0b355c --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activation of store operated calcium channel activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Acylglycerol transport", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine catabolic process", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp metabolic process", "Amp salvage", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Arterial endothelial cell differentiation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Bile acid signaling pathway", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into cytosol", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in cardiac muscle cell fate commitment", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac cell fate commitment", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell fate commitment", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell myoblast differentiation", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine secretion", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide 1 phosphate transport", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Choline transport", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Commissural neuron axon guidance", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion import", "Copper ion transmembrane transport", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid receptor signaling pathway", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial skeletal system development", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytolysis by host of symbiont cells", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine secretion", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal aorta development", "Dorsal aorta morphogenesis", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Elastic fiber assembly", "Elastin metabolic process", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardial cushion development", "Endocardial cushion formation", "Endocardial cushion morphogenesis", "Endocardium development", "Endocardium morphogenesis", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil mediated immunity", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial to mesenchymal transition involved in endocardial cushion formation", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of left right asymmetry", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat pad development", "Fat soluble vitamin biosynthetic process", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated inhibitory signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Heat generation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Heparin biosynthetic process", "Heparin metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "Hexose phosphate transport", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k119 monoubiquitination", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus development", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune effector process", "Immune response", "Immune response inhibiting cell surface receptor signaling pathway", "Immune response inhibiting signal transduction", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Inhibitory postsynaptic potential", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell fate commitment", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Iodide transport", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein particle remodeling", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteinizing hormone secretion", "Luteolysis", "Lymph vessel development", "Lymphatic endothelial cell differentiation", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage differentiation", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Mast cell proliferation", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Melanosome assembly", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane fusion involved in viral entry into host cell", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Menaquinone metabolic process", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell fate commitment", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myoblast proliferation", "Myofibroblast differentiation", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immune response to tumor cell", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of astrocyte activation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of camp mediated signaling", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of catecholamine secretion", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular amine metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular response to vascular endothelial growth factor stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of ceramide biosynthetic process", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of dopamine secretion", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of g0 to g1 transition", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of histone acetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein metabolic process", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage activation", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage derived foam cell differentiation", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microglial cell activation", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuroinflammatory response", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl cysteine s nitrosylation", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sphingolipid biosynthetic process", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell differentiation in thymus", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor 2 signaling pathway", "Negative regulation of toll like receptor 4 signaling pathway", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nitrogen utilization", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Norepinephrine metabolic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation cycle", "Ovulation cycle process", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parathyroid gland development", "Paraxial mesoderm development", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification process", "Penetration of zona pellucida", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl l cysteine s palmitoylation", "Peptidyl lysine acetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericardium development", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine acyl chain remodeling", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyamine transmembrane transport", "Polyamine transport", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic process involved in development", "Positive regulation of apoptotic process involved in morphogenesis", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of b cell receptor signaling pathway", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell proliferation involved in heart morphogenesis", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of complement activation", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental pigmentation", "Positive regulation of developmental process", "Positive regulation of digestive system process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of enamel mineralization", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of heat generation", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of inhibitory postsynaptic potential", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage derived foam cell differentiation", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic nuclear division", "Positive regulation of melanocyte differentiation", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myoblast proliferation", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immune response to tumor cell", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of store operated calcium channel activity", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tooth mineralization", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of uterine smooth muscle contraction", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor receptor signaling pathway", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein palmitoylation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adiponectin secretion", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte activation", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid secretion", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of development heterochronic", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of enamel mineralization", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate secretion", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of heat generation", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intestinal lipid absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage derived foam cell differentiation", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic nuclear division", "Regulation of melanocyte differentiation", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myoblast proliferation", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immune response to tumor cell", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pattern recognition receptor signaling pathway", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl cysteine s nitrosylation", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigment cell differentiation", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic cytosolic calcium ion concentration", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rab protein signal transduction", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle cell proliferation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of store operated calcium entry", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell apoptotic process", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 2 signaling pathway", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription from rna polymerase ii promoter involved in heart development", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell proliferation", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wnt signaling pathway involved in heart development", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to herbicide", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lithium ion", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cell programmed cell death", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Sebaceous gland development", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary heart field specification", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of bitter taste", "Sensory perception of chemical stimulus", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory perception of sweet taste", "Sensory perception of taste", "Sensory system development", "Septum primum development", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermidine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Store operated calcium entry", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Tolerance induction to self antigen", "Toll like receptor 2 signaling pathway", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by trans synaptic complex", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription factor catabolic process", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type b pancreatic cell proliferation", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Udp n acetylglucosamine transmembrane transport", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urea cycle", "Urea metabolic process", "Urinary bladder smooth muscle contraction", "Urinary tract smooth muscle contraction", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APOB", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C2CD5", "C3orf58", "C5orf51", "CAAP1", "CAB39", "CACYBP", "CAD", "CALR", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPI", "CENPP", "CENPQ", "CENPU", "CENPV", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COG2", "COG5", "COG6", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAM162A", "FAM192A", "FAM207A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMC1", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "M6PR", "MACF1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS27", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NEPRO", "NES", "NFATC2IP", "NFS1", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "ROMO1", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RSRC1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35A4", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPNS1", "SPOP", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF3", "TM9SF4", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM33", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPYL1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBIAD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "UROD", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YIF1A", "YIF1B", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZCCHC17", "ZCCHC3", "ZCCHC8", "ZDHHC20", "ZEB2", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF148", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["AASDHPPT", "ABCB1", "ABCC1", "ABCE1", "ABHD12", "ABI1", "ACADVL", "ACAT2", "ACBD3", "ACOT8", "ACOX3", "ACP6", "ACTN4", "ADAR", "ADD1", "ADD3", "ADK", "AFDN", "AHCYL1", "AIFM1", "AKAP1", "AKAP8", "AKAP8L", "AKR1B1", "AKT2", "ALDH1B1", "ALDH2", "ALKBH5", "ALYREF", "ANAPC7", "ANK3", "ANKLE2", "ANLN", "ANO6", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP2M1", "AP3B1", "AP3M1", "APEH", "APLP2", "APOB", "APRT", "ARFGAP1", "ARFIP1", "ARHGEF2", "ARL1", "ARL2", "ARL3", "ARL8B", "ASNA1", "ATAD1", "ATAD3A", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B4", "ATP2C1", "ATP5L", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP7A", "ATP7B", "AUP1", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG6", "BAIAP2", "BASP1", "BAX", "BCAP31", "BCAS3", "BCCIP", "BCOR", "BLMH", "BLVRA", "BNIP1", "BRCA1", "BRMS1L", "BUB1B", "BYSL", "C12orf73", "C19orf70", "C3orf58", "CAD", "CALR", "CAMK2G", "CAPN2", "CARM1", "CCAR2", "CCDC134", "CCDC22", "CCDC47", "CCNB1", "CCT2", "CD2AP", "CD47", "CDC23", "CDC37", "CDC42", "CDC73", "CDCA5", "CDCA8", "CDH2", "CDK1", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2A", "CELF1", "CELF2", "CENPP", "CERS1", "CERS2", "CFL2", "CHCHD3", "CHMP2A", "CHMP6", "CHMP7", "CHP1", "CHST14", "CHTOP", "CIAPIN1", "CIRBP", "CKAP2", "CLASP1", 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0000000000000000000000000000000000000000..114c3a14eed2429dc44cf7581f6a62bbf0e1f94d --- /dev/null +++ b/msigdb_gocc/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8a016e261fd30e8aef40c353f3389bc0d0bd5dafc4f5e47474a69b0d4b2e87dc +size 185033 diff --git a/msigdb_gocc/df_merge.tsv b/msigdb_gocc/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..135aff393ddb1ecf8a88d4ebbcb798159ab8dade --- /dev/null +++ b/msigdb_gocc/df_merge.tsv @@ -0,0 +1,30 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Organelle inner membrane 42 258 3.3473937638877724 0.000815752478753 79.6747572815534 237.5995145631068 1.5941979045672914 0.3906136455525962 32.81710191865129 21.467005610038825 2.570753705211445 0.4244355950981394 1.536685019495467e-05 6.540596558644666e-06 3.754023327159058e-08 9.041751996885989e-09 8.324450203850237e-10 +Mitochondrial envelope 57 336 3.0362829266793123 0.0023951450184871 98.51456310679612 309.05582524271847 1.3784407074331837 0.4315621435689855 37.853540978552445 29.592036616547553 2.6690149272426917 0.4358105924461398 0.0003090716806581 0.0001752376033939 1.1624915082453469e-07 5.6858715889392245e-11 6.292554231141559e-12 +Endocytic vesicle 22 84 2.919739820388166 0.0035032372965468 19.521844660194176 83.27669902912622 0.428513908443532 0.5353120905813061 7.647069906220736 7.607555057832984 1.324058617895936 0.3761698531660883 0.589824893083101 0.6294205244747506 0.1330886303833328 0.0013777303127351 4.6190893833988185e-05 +Golgi apparatus 57 300 2.881501705454883 0.0039578509276052 79.29126213592232 307.80825242718447 1.0941692666231844 0.5225509759640199 24.90716006851961 39.34912971804267 1.7376904428153446 0.4394682295132952 0.6479398024095182 0.7303300104462217 0.3806622037558752 0.0070451480548815 0.0043048750979148 +Endocytic vesicle membrane 18 43 2.8361025473818686 0.0045667780108868 11.41019417475728 40.75728155339806 0.6528171904926832 0.3529092384633215 4.825015011915381 4.780047567333447 1.5638167276319088 0.3380752375601685 1.0 1.0 0.2961867551178612 0.0198065600649204 2.711469626210813e-05 +Postsynaptic density membrane 2 5 2.523511602882026 0.0116189226203604 1.8106796116504855 6.669902912621359 0.9700827983290172 0.2992953748741365 1.3610684424812354 1.822930264123012 0.935271302642404 0.2569047527325972 0.140685207080191 0.1553991536419083 0.2872333566147377 0.2076979954646016 0.2375667468636007 +Tim23 mitochondrial import inner membrane translocase complex 3 9 2.508042121029063 0.012140219456634 2.2694174757281553 6.342233009708738 1.5180442383336388 0.125307709046494 1.369833329272529 0.8106469094037756 1.2674744491900518 0.2021471972412396 0.0009766247838039 1.6752670706047648e-05 0.0001343549216781 9.701143498590324e-05 0.001347246206883 +Proteasome core complex beta subunit complex 4 7 2.5052883345864547 0.0122351606009831 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 1.0 1.0 0.0031504918831051 9.327097249989188e-07 9.088718771147158e-07 +Postsynaptic specialization intracellular component 2 5 2.435327519234205 0.0148783159399079 0.9368932038834952 4.580097087378641 1.0243451866343556 0.3526172805798264 1.2251007718616247 0.7111401963913695 0.8141106380508738 0.2958370422450036 1.0 1.0 0.0743799864466655 0.0148625463558957 0.005213052276273 +Centriolar satellite 2 22 2.4297828580132013 0.0151078711058396 6.631067961165049 24.325242718446603 0.3067804976927401 0.628129362137114 3.814866909745424 4.218089072853329 0.8031313068812725 0.3161655469328873 0.0562694504679229 0.0680396063598938 0.0540767090111314 0.3661388620186562 0.6286617742637264 +Clathrin coated vesicle 12 42 2.4179196977316444 0.0156095211874212 9.936893203883496 47.157766990291265 0.2628715125167937 0.534532305855711 4.553447222704333 4.879804116719352 1.1779559306555245 0.358217133589648 0.0971155489483074 0.1162566833370341 0.3281099840481742 0.3425620879071548 0.0058861787677492 +Inner mitochondrial membrane protein complex 19 84 2.3914703169757927 0.0167810408355308 27.97087378640777 75.4635922330097 1.520604987560478 0.2664687480104057 12.043574857699111 6.447783897817093 2.3558486082891616 0.3692317407906862 0.0190902250974751 0.0036241696225553 0.0002703653485467 8.329903907889915e-05 1.2383667438952385e-06 +Perinuclear endoplasmic reticulum 0 5 2.346122048684742 0.0189698945719887 1.6432038834951457 4.907766990291262 0.0984317083916917 0.5173522806947106 1.2153458204502492 1.0456743372068014 0.926891313356721 0.2925044271694717 0.062853835992264 0.0697581245313758 0.1349531130589082 0.307957256786686 0.0329439287769651 +Proteasome core complex 5 15 2.303840611883381 0.0212315924500254 5.325242718446602 14.563106796116504 1.2215341624098188 0.3078540255827756 2.4387733048296822 0.5516067072365743 1.1166106206832802 0.3218631020970666 1.0 1.0 0.0113213926532688 1.8818469985730976e-06 7.441528927979243e-06 +Early endosome 16 78 2.2922531930712355 0.0218910370843372 24.66504854368932 96.93203883495146 0.530758374709677 0.5743319290889299 8.086272783051246 14.025470683081796 1.1449007118883376 0.3721207721610414 0.1213808717193412 0.1532286578704182 0.2869551331057779 0.5281964166728911 0.2034327811777965 +Postsynaptic specialization membrane 1 8 2.2531566454527128 0.0242492739046817 2.4199029126213594 10.24271844660194 0.7861101002372709 0.3813630835285081 1.6578416165380507 2.0900412009571863 0.9115241808638076 0.2917173074219844 0.162776730222371 0.1795501084992132 0.327507803675052 0.2616785322574622 0.3172421403160574 +Snare complex 8 16 2.247410604936243 0.0246137978823937 6.20873786407767 15.79368932038835 0.8138466711937282 0.3737991711938105 3.1112263618988054 3.010283181947674 1.1802712183474584 0.3261149602927671 1.0 1.0 1.0 0.6524035152067593 0.0163662094716421 +Messenger ribonucleoprotein complex 4 5 2.2209358860949395 0.0263553041979103 2.1432038834951457 4.978155339805825 0.6946670661171017 0.4479616993324847 1.1952078371419346 0.8401389709046068 0.8841292807137072 0.3125159243383019 1.0 1.0 1.0 0.2175647207167039 0.0808987135784085 +Apical plasma membrane 10 50 2.187657035831494 0.0286945938697698 13.313106796116504 44.91504854368932 0.8056122914935105 0.4638533528605782 6.08368206230376 5.803837594461636 1.1490032654706197 0.3657186109722784 0.1483953887820343 0.1757629685498992 0.194273291085049 0.0146509945269355 0.0204462262439837 +Lipid droplet 7 33 2.1844098258745306 0.0289321468466097 7.313106796116505 30.72087378640777 0.9597061621709796 0.3916106255858687 3.663189105886808 2.181620314734523 1.1934081113966928 0.3497541884861006 0.0327906271320101 0.0038595506966638 0.0254749821013702 0.0051340314390508 0.0042012874470427 +Chromosome telomeric repeat region 0 5 2.180432379896646 0.0292254261388449 1.970873786407767 4.179611650485437 -0.5579233261109299 0.5105601033595861 1.2634235403547602 0.6322803887211381 0.7776378549417727 0.2980429492374385 0.0547019579410807 0.0607401038440192 0.1180585699575878 0.2731207001200411 0.4744622644152227 +Vesicle membrane 63 240 2.1103169018891026 0.0348310687075714 59.03398058252427 252.66747572815535 0.5350285241159404 0.6113983912197217 17.512237349079548 29.567983380691818 1.3292572988488431 0.402876017449685 0.4265822340263817 0.5109691688089031 0.4618570263014726 0.0802217788181489 0.0119811618795963 +Endosome 35 181 2.027824060627549 0.0425782077791001 49.68446601941748 210.85679611650485 0.3589512364806963 0.6263779709054735 15.417095902733692 27.960293924368397 1.2603534839168704 0.3964197633252465 0.3434312889357372 0.4213184222052407 0.4917919823223609 0.0438282175868472 0.1205112235069186 +Envelope 71 494 2.0246875963482123 0.0428994530765747 133.55825242718447 476.99271844660194 1.1125762168925015 0.4931727688685032 47.82674034566458 40.415168802184624 2.6300132137901633 0.4489464989697134 0.0001904664560042 0.0001618781339786 4.855967560967177e-06 9.60545939343863e-10 1.0519258904670065e-11 +Golgi membrane 55 138 1.9983784483033389 0.0456756463442564 41.28398058252427 131.19174757281553 1.6327747521284677 0.3511039607499193 15.277988344159814 17.44963987873233 1.926180921267262 0.4033858283713009 0.5529365257734473 0.611897199111217 0.388119857036501 0.015151225604853 0.0139929712085834 +Golgi transport complex 3 5 1.9973947979755289 0.0457823124837091 1.6407766990291262 3.9757281553398056 -0.0759035663653856 0.5528679483092231 1.3749094863909204 1.7304786934905476 1.019411789610248 0.3179528979536178 1.0 1.0 1.0 0.1981219124770219 0.0075416763583454 +Striated muscle thin filament 3 5 1.993580794860193 0.0461978858968312 2.0776699029126213 4.036407766990291 0.3903791791430543 0.4433177448944362 1.1590866875641097 0.8708520037106524 1.0789606331951869 0.3204744543463996 1.0 1.0 1.0 1.0 0.359364707162026 +Myofilament 3 5 1.993580794860193 0.0461978858968312 2.174757281553398 4.186893203883495 0.404875148061941 0.4374833583964219 1.241883821669583 1.0388207738802084 1.088024284468753 0.3207832055944606 1.0 1.0 1.0 1.0 0.390305373111191 +External encapsulating structure 5 33 1.975241882245678 0.0482407050867921 8.740291262135923 33.067961165048544 0.2475250746714072 0.5329464629763961 4.007036034183376 4.3711590871852435 1.0928778643562622 0.3321243069645864 0.5214457461789757 0.559981185156499 0.2216305912196411 0.2266833636016097 0.8314919811725522 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c3c01aef693a0810fda69b7df174cf621e1932eb --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 895, + "title": "Average number of proteins per term", + "value": 28.287150837988825 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c9f6922804067684d930ea3132f168957f49fccf --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6b9cf963f319c6e770743f3d8d1c4a4a9232bc08 --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,292 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Organelle inner membrane 0.4074738105751825 3.3473937638877724 0.000815752478753 0.5182820105792458 0.0140403551631542 258 Q9P0J0,Q567V2,Q9UDX5,O60830,Q70HW3,Q99720,Q99595,P23786,Q69YU5,O43772,P03886,P14406,O96000,P49406,P09669,P49748,Q9BUP0,O95182,Q9H061,Q6DKK2,P60602,Q13505,Q5XKP0,Q9Y375,P13073,Q96IX5,O95831,P22830,P00846,O95563,P51970,Q96CU9,Q9Y584,Q8TBP6,Q86VD7,Q13423,Q7KZN9,O43819,Q9Y619,P62072,Q10713,Q9BQT8 42 +Microtubule organizing center attachment site 0.8521514073115484 3.3268568541931467 0.0008783147952824 0.5445353453250038 0.0146967178855488 2 Q8WXH0 1 +Intrinsic component of postsynaptic density membrane 0.8502102879327138 3.317756247515145 0.0009074363681498 0.5562634561220852 0.0147664645362563 2 P23634 1 +Histone pre mrna 3 end processing complex 0.8372694920737696 3.256809565220725 0.0011267199651083 0.6354103834498358 0.0166189945090537 2 P67809 1 +Mhc protein complex 0.8359754124878688 3.250688315916422 0.0011512599548171 0.6433396074906572 0.0166189945090537 2 P10321 1 +Mhc class i protein complex 0.8359754124878688 3.250688315916422 0.0011512599548171 0.6433396074906572 0.0166189945090537 2 P10321 1 +Tim22 mitochondrial import inner membrane insertion complex 0.8938230782673604 3.2403610410348014 0.0011937844179625 0.6566741572286958 0.0169593183186748 3 Q9Y584 1 +Protein phosphatase 4 complex 0.8058880621158309 3.106980959892742 0.0018900857182966 0.8160750334236315 0.0222092392697788 2 Q8TF05 1 +Myosin filament 0.7965059851180862 3.0616151686872004 0.0022014628405087 0.8608887368607457 0.0243248054599418 2 P35580 1 +Mitochondrial envelope 0.36705911773985 3.0362829266793123 0.0023951450184871 0.8830754097960816 0.025519699899357 336 Q9P0J0,Q567V2,Q9UDX5,O60830,Q70HW3,Q9NS69,Q99595,P23786,Q69YU5,O43772,Q9HCL2,P03886,P14406,Q96AY3,O96000,P49406,P09669,P49748,Q8N4H5,Q9BUP0,O95182,Q9H061,Q6DKK2,P60602,Q13505,Q5XKP0,Q9Y375,P13073,Q96IX5,O95831,P22830,P00846,O95563,O43464,P51970,P09601,Q9NX63,Q96CU9,P52888,Q9Y584,Q9BYT8,Q13794,Q9H974,Q8TBP6,Q5VT66,Q86VD7,Q96RL7,Q13423,Q7KZN9,O43819,P50416,Q9Y619,Q9P0S9,P62072,Q96H78,Q9BQT8,Q10713 57 +Endocytic vesicle 0.5064096465431432 2.919739820388166 0.0035032372965468 0.9567562368788328 0.0330041829516786 84 P11717,Q9Y4G8,Q14108,P04114,P02786,Q16625,Q13555,Q9Y487,Q5KU26,P08670,P50570,Q6WKZ4,Q06481,Q8WTV0,O00461,P07948,Q9BZG1,Q03518,Q14C86,P51790,P20645,Q93050 22 +Golgi apparatus 0.3565731347081049 2.881501705454883 0.0039578509276052 0.9712553907223384 0.0350573472020537 300 Q5VW38,Q6P1K2,Q4J6C6,P0CG08,O15118,P11717,Q8NEY8,Q9HC07,Q14108,P50897,P80303,O14653,Q92896,Q5BJH7,O60476,P24390,Q6IQ22,Q92520,Q15392,Q96PU5,Q9UQB8,Q9NPR9,O14773,Q96M27,Q8NCH0,Q9NX40,P50570,Q9UI14,Q9Y5P4,Q9P260,Q8IZA0,O75503,Q9GZM5,Q6ZRP7,O43823,Q9Y2V7,Q9BRK5,P53367,Q9NQX7,O15126,O00461,Q96RL7,Q9BZG1,P07948,P83436,P60520,P51572,P51790,Q9H3P7,P20645,Q9Y282,O43852,O43290,O95456,Q10713,Q93050,O43731 57 +Presynaptic cytosol 0.8710079060818023 2.881206502941753 0.0039615599544751 0.9713510306005576 0.0350573472020537 4 Q9UQB8 1 +Intrinsic component of postsynaptic specialization membrane 0.8094946046757434 2.85603606672702 0.0042896640245624 0.9786671570605252 0.036219333037579 3 P23634 1 +Endocytic vesicle membrane 0.5826457884981058 2.8361025473818686 0.0045667780108868 0.9833713413975634 0.0381987506518109 43 P07948,Q9BZG1,P50570,Q03518,Q13555,P20645,P11717,Q6WKZ4,Q9Y487,Q06481,Q14108,Q8WTV0,P04114,Q93050,P02786,P04439,Q5KU26,P10321 18 +Postsynaptic density intracellular component 0.8529726227167711 2.8017419640039956 0.0050827509551416 0.9895448678229252 0.0402571867685998 4 Q9UQB8 1 +Platelet alpha granule membrane 0.7744274720780259 2.690455804761973 0.0071354485609782 0.9983535267860416 0.0519205403420775 3 Q06481 1 +Dendritic shaft 0.7646493896777751 2.6436561010634025 0.0082015937807808 0.9993705685700268 0.0575248559250001 3 Q9UQB8 1 +Triglyceride rich plasma lipoprotein particle 0.7448383002968489 2.5479800703020543 0.010834866071621 0.9999417124285334 0.072911316797751 3 Q9UHG3 1 +Postsynaptic density membrane 0.8357994511818887 2.523511602882026 0.0116189226203604 0.9999713346082753 0.0753546068494392 5 Q99720,P23634 2 +Tim23 mitochondrial import inner membrane translocase complex 0.8406542357440664 2.508042121029063 0.012140219456634 0.9999821228979786 0.0781690389473916 9 O60830,Q99595,P60602 3 +Proteasome core complex beta subunit complex 0.8649711853928109 2.5052883345864547 0.0122351606009831 0.999983596414169 0.0782176338419995 7 P28070,P49721,P28074,Q99436 4 +Haus complex 0.7850186641527612 2.494943605488906 0.0125977150002929 0.999988190147376 0.0794010910229731 4 Q9H6D7 1 +Excitatory synapse 0.7726844924245158 2.437975148514458 0.014769789358235 0.999998354644542 0.0881953865739429 4 Q9UQB8 1 +Postsynaptic specialization intracellular component 0.8157271876115377 2.435327519234205 0.0148783159399079 0.9999985091243848 0.0881953865739429 5 Q9UQB8,P50570 2 +Centriolar satellite 0.6302723684297277 2.4297828580132013 0.0151078711058396 0.9999987898013885 0.0883761087563823 22 P41440,Q13045 2 +Clathrin coated vesicle 0.5338798660015442 2.4179196977316444 0.0156095211874212 0.9999992329441044 0.0907176718359868 42 P04114,P50570,P51572,Q5VW38,P20645,P11717,Q14108,Q8NC96,Q9H267,P42892,P02786,O15126 12 +Inner mitochondrial membrane protein complex 0.4579262406779996 2.3914703169757927 0.0167810408355308 0.9999997357781714 0.0944593179106927 84 Q9P0J0,O60830,Q99595,P03886,P14406,O96000,P09669,O95182,P60602,Q13505,Q5XKP0,Q9Y375,P13073,Q96IX5,P00846,P51970,Q96CU9,Q9Y584,P62072 19 +Cuticular plate 0.6609511484956343 2.3747712640004623 0.0175598281248166 0.99999986999184 0.0964174611761402 2 Q01082 1 +Myosin ii complex 0.7555717376443674 2.3582717112353997 0.0183602487795961 0.9999999373151846 0.1001976991325523 4 P35580,P14649 2 +Hulc complex 0.6573924296344242 2.355912309091996 0.0184772789617619 0.9999999436596032 0.1002252404289514 2 Q5VTR2 1 +Dendritic spine membrane 0.6964551258936411 2.3094171765072113 0.0209204427879738 0.9999999939452728 0.1053880196734955 3 P23634 1 +Dendrite membrane 0.6964551258936411 2.3094171765072113 0.0209204427879738 0.9999999939452728 0.1053880196734955 3 P23634 1 +Proteasome core complex 0.7006734214394593 2.303840611883381 0.0212315924500254 0.9999999954443656 0.1053880196734955 15 P49721,Q99436,P28070,P28074,Q92530 5 +Early endosome 0.4546375135124336 2.2922531930712355 0.0218910370843372 0.999999997507825 0.1070627223523598 78 Q13614,Q9BZF3,Q96J02,P41440,P31751,Q9UIQ6,Q5VW38,P51790,P11717,O15400,Q06481,Q9HC07,P04114,Q9H267,P02786,P10321 16 +Nuclear envelope lumen 0.7346325552455588 2.259691762939844 0.0238403878847155 0.9999999995820278 0.1126887568844733 4 P11717 1 +Postsynaptic specialization membrane 0.7956587181524335 2.2531566454527128 0.0242492739046817 0.9999999997127234 0.1126887568844733 8 Q99720 1 +Golgi lumen 0.7327930588528615 2.2509759959150304 0.0243870577559683 0.9999999997468314 0.1126887568844733 4 O00461 1 +Snare complex 0.6784818564356381 2.247410604936243 0.0246137978823937 0.9999999997943808 0.1129710210499608 16 O75396,Q12981,Q13277,O60499,Q9P2W9,O15400,Q13190,O14653 8 +Outer kinetochore 0.7306571706053783 2.240844625648894 0.0250361411713184 0.9999999998604524 0.114323195654745 4 P14635,O60566,P53350 3 +Messenger ribonucleoprotein complex 0.7678108808290146 2.2209358860949395 0.0263553041979103 0.9999999999584616 0.1185326495333152 5 P67809,P51991,Q99729,Q9NUL3 4 +Apical plasma membrane 0.4822275921839532 2.187657035831494 0.0286945938697698 0.9999999999951756 0.1258904976149214 50 P30825,Q16181,P41440,Q16625,P51790,Q8WWI1,Q9Y4G8,P23634,Q9Y6M7,P08183 10 +Lipid droplet 0.552203973027126 2.1844098258745306 0.0289321468466097 0.999999999996124 0.1263135191595887 33 Q96RL7,Q9H6V9,O43760,Q99720,P48449,Q8NBX0,P04114 7 +Golgi medial cisterna 0.7084748026848837 2.1349104476328393 0.0327683257673296 0.999999999999888 0.1332025919939762 4 P04439,Q16706 2 +Vesicle membrane 0.3499588176810725 2.1103169018891026 0.0348310687075714 0.9999999999999836 0.1391687789878413 240 Q13614,Q9BZF3,P42785,Q13576,O60831,P30519,P11717,O75396,O15118,Q9HC07,Q14108,Q8NC96,P04114,P42892,P02786,Q9Y5K8,P84095,O14653,P10321,Q9BXS5,P24390,Q9UHQ9,Q13555,Q6IQ22,Q96AX1,P62993,Q9Y487,O00264,O60749,Q13190,Q5KU26,Q96J02,Q9NVJ2,Q6IAA8,P50570,Q08722,Q4KMQ2,Q9UIQ6,O94979,Q6WKZ4,Q06481,P27105,Q8WTV0,Q9NQX7,O15126,O00461,Q96RL7,Q9BZG1,P07948,O75787,O43760,Q9UBB6,Q03518,Q9H267,P51790,P20645,Q9NRW7,O15400,Q9Y2T2,O60499,Q93050,P04439,O43731 63 +Sorting endosome 0.6069233257845414 2.0837593101712035 0.0371820662549531 0.999999999999998 0.1465844612732273 2 P18031 1 +Platelet dense tubular network 0.6062762859915942 2.0802133498553497 0.0375059683034291 0.9999999999999988 0.1465844612732273 2 Q9H4M9 1 +Platelet dense tubular network membrane 0.6062762859915942 2.0802133498553497 0.0375059683034291 0.9999999999999988 0.1465844612732273 2 Q9H4M9 1 +Dynactin complex 0.6935121471462531 2.062722104325622 0.0391390385446055 0.9999999999999996 0.1516425952269348 4 Q9UJW0,Q13561 2 +Vacuolar proton transporting v type atpase v0 domain 0.686823859107424 2.030264723796388 0.0423296379222573 1.0 0.1598524301283556 4 Q93050,Q9Y487 2 +Proton transporting v type atpase v0 domain 0.686823859107424 2.030264723796388 0.0423296379222573 1.0 0.1598524301283556 4 Q93050,Q9Y487 2 +Endosome 0.3670421303694657 2.0278240606275495 0.0425782077791001 1.0 0.1601155292533388 181 Q13614,Q9BZF3,Q5VW38,P11717,O15118,Q9HC07,Q9Y4G8,Q14108,P04114,P42892,P02786,O14653,P41440,Q6IQ22,Q9Y487,Q96PU5,O14773,Q9NX40,Q96J02,P50570,Q9UIQ6,Q9P260,Q6WKZ4,Q06481,Q9BRK5,O15126,O00461,Q96RL7,Q9UBB6,P31751,Q14C86,P51790,P20645,O15400,Q93050 35 +Envelope 0.3183052584681358 2.0246875963482123 0.0428994530765747 1.0 0.1606485795126961 494 Q9BZF3,Q9P0J0,Q567V2,Q9UDX5,O60830,Q70HW3,Q99720,Q9NS69,P11717,Q99595,P23786,Q69YU5,O43772,O15118,P03886,Q9HCL2,P14406,Q96AY3,O96000,Q5BJF2,P80303,P09669,P49406,P49748,Q8N4H5,Q9BUP0,O95182,P67809,Q9H061,Q6DKK2,P07437,P60602,O15173,Q13505,Q5XKP0,Q8WWI1,Q9Y375,P13073,Q96IX5,O95831,P22830,P00846,O95563,Q92575,O43464,P51970,P09601,Q9NX63,Q96CU9,P52888,Q6ZRP7,Q9Y584,Q9BYT8,Q13794,Q96EE3,Q9H974,Q8TBP6,Q5VT66,Q86VD7,Q96RL7,Q13423,Q7KZN9,O43819,P50416,Q9Y619,Q9P0S9,P62072,Q96H78,Q9BQT8,Q10713,Q96RT1 71 +Mcrd mediated mrna stability complex 0.6846579329744337 2.019728867952429 0.0434115189933397 1.0 0.1618887895793294 4 O60506 1 +Golgi membrane 0.3708996901075947 1.9983784483033389 0.0456756463442564 1.0 0.1686220974194225 138 Q99653,Q86SF2,Q16706,P0CG08,O75396,P36405,O15027,P11717,O95070,Q9HC07,Q14108,P40616,O14653,Q92896,P10321,Q5BJH7,O60476,Q9BXS5,P24390,Q6IQ22,Q15392,O00400,Q13190,Q8NCH0,Q8TBA6,Q8N6T3,Q9Y2D2,P50570,Q14746,Q8IZA0,Q6ZRP7,Q9UP83,Q9P2W9,Q8N2H4,Q8NDZ4,Q9Y2V7,P53367,O00461,P83436,Q6NTF9,P35670,P60520,Q92538,P51572,P51790,Q9H3P7,Q9NRW7,Q9Y282,P11166,O60499,Q10713,P62070,O43731,P04439,O43505 55 +Golgi transport complex 0.7191030724348142 1.9973947979755289 0.0457823124837091 1.0 0.1686220974194225 5 P83436,Q9UP83,Q9Y2V7 3 +Striated muscle thin filament 0.7182824463011662 1.9935807948601931 0.0461978858968312 1.0 0.1687637056231183 5 P67936,Q9NYL9,P28289 3 +Myofilament 0.7182824463011662 1.9935807948601931 0.0461978858968312 1.0 0.1687637056231183 5 P67936,Q9NYL9,P28289 3 +External encapsulating structure 0.5240714941877195 1.975241882245678 0.0482407050867921 1.0 0.1727017242107158 33 Q32P28,P55081,Q96RT1,Q5KU26,Q92896 5 +Organelle envelope lumen 0.5122731737086101 1.9498242405089508 0.0511970713038747 1.0 0.1818308683213012 35 P07948,P17655,O43464,P51970,P07437,P11717,P52888,P62072,Q9BYT8,Q9UJZ1,Q96AY3,O95831 12 +Dendritic growth cone 0.6239482200647267 1.938759178299093 0.0525306689678612 1.0 0.1831135657654938 3 Q7L576,P07900 2 +Dendrite terminus 0.6239482200647267 1.938759178299093 0.0525306689678612 1.0 0.1831135657654938 3 Q7L576,P07900 2 +Endoplasmic reticulum 0.3134708981359883 1.938330587998502 0.0525829028824564 1.0 0.1831135657654938 510 Q9BZF3,Q96PC5,Q8NBM4,Q9H6V9,Q99720,P30519,Q5BJF2,Q7Z2K6,Q13641,O60476,Q9UMX5,Q9UNW1,Q9UQB8,Q9BRK0,P09601,Q8TBX8,Q8IY17,Q14257,O60725,O95456,Q16850,O95302,P07099,O43731,P36578,Q9HD20,Q9H6E4,Q32P28,Q86YN1,Q9NWM8,O15118,Q9NZ08,Q96AY3,P80303,O14653,Q5BJH7,Q92791,P24390,Q53GQ0,O15173,Q13555,Q9BRR6,Q92530,Q96HY6,Q5VV42,Q92575,Q9Y5P4,P48449,O75503,Q9BRK5,P38435,Q96RL7,Q9Y282,Q6PIU2,Q8NHH9,Q9NUQ7,Q96G23,Q00765,Q9BTZ2,Q14108,P04114,P84095,O75718,Q15392,P43307,P13674,Q86XL3,O43464,Q12981,Q06481,P27105,O60762,Q15631,Q03518,P60520,P51572,O43852,Q9NPA0,Q9H2J4,Q15800,Q8TDW0,Q8N0U8,Q9Y3D6,P10321,O43390,O95793,P17655,P23396,Q9UHQ9,Q8IXB1,O95470,O43681,A1L0T0,Q13190,Q8WXH0,Q9Y2B2,P51571,Q9Y2G5,Q9P2W9,Q92643,P28161,O75844,O75787,Q9NUL3,P26885,O60506,P04439 107 +Endoplasmic reticulum tubular network membrane 0.6211751312298563 1.9242747385017576 0.0543201552647913 1.0 0.1869866883153395 3 Q8NHH9 1 +Mitochondrial crista 0.6626740045322128 1.9121096927401704 0.055862125880709 1.0 0.1901164693634109 4 P07948,P18031,O60313 3 +Cis golgi network 0.6178705767817818 1.9069202898940216 0.0565309103077753 1.0 0.1901164693634109 16 O00461,O43731,Q9NPR9 3 +Respirasome 0.4605056477587653 1.9065199979380132 0.0565827736374042 1.0 0.1901164693634109 47 Q9P0J0,Q13423,Q7KZN9,O95182,Q6DKK2,Q96CU9,Q9Y375,P03886,P13073,P14406,O96000,P09669 12 +Coated vesicle 0.4134539410478756 1.9037487778439108 0.0569429104305356 1.0 0.1901638240124232 86 Q5VW38,P11717,Q14108,P04114,Q8NC96,P42892,P02786,P10321,O14653,Q5BJH7,P24390,Q96AX1,P50570,O15126,P51572,P20645,Q9Y282,Q9H267,O43731 19 +Trans golgi network membrane 0.5250308036140018 1.8730486968345392 0.0610616607950356 1.0 0.202408097820581 29 P83436,Q14746,Q9BXS5,P35670,P20645,P11717,O15127,Q9UP83,O60499,Q9HC07,Q9Y2V7,P53367,P40616,O15126 14 +Caveola 0.633876496640451 1.7986052965039443 0.072081138942003 1.0 0.2312280263551711 13 P41440,P09601,Q8WTV0 3 +Perinuclear region of cytoplasm 0.3542518549615338 1.7773466071974209 0.0755112297378592 1.0 0.2354792704368782 167 Q13614,Q9BZF3,P11717,O15118,Q9Y4G8,P42892,P02786,Q96S55,Q99627,Q9Y487,P25205,O95831,Q92530,P16989,P50570,Q9Y5P4,Q96F07,Q9UIQ6,P09601,O75503,P27105,Q9NQX7,P07948,Q9BZG1,P51572,P20645,O15400,Q9H2J4,Q93050 29 +Vacuolar membrane 0.3663624530764792 1.7753062751629396 0.0758473298418007 1.0 0.2357061118347627 117 Q13614,P42785,O15118,Q9HC07,Q14108,P42892,Q8NHS3,P41440,Q16625,Q6IQ22,Q9Y487,Q9UIQ6,O75503,P27105,Q96EE3,Q8WTV0,Q9NQX7,Q96RL7,P07948,P60520,P51790,P20645,O15400,Q93050 24 +Presynapse 0.3987953904223322 1.7398930965104942 0.0818777911161683 1.0 0.249253819894458 87 Q13614,Q13641,P50570,P41440,Q9UI14,O43760,P51790,Q6IQ22,P50897,O15400,Q9BT78,Q9UQB8,P23634,P05771,O15126 15 +Dna replication preinitiation complex 0.6743267789922446 1.7361291190735122 0.0825410066599192 1.0 0.2504210202055177 9 P25205,Q9BRT9,Q9BRX5 3 +Cortical endoplasmic reticulum 0.5840504429746134 1.7282946176798486 0.0839354175438986 1.0 0.2537912118303693 3 P50402 1 +Apical part of cell 0.4070742725829558 1.7228155638389666 0.0849218833307992 1.0 0.2559093790608259 60 P30825,Q16181,P41440,Q16625,P51790,Q8WWI1,Q9Y4G8,P23634,Q9Y6M7,P08183 10 +Phagocytic vesicle 0.4493039640143957 1.718799264616219 0.0856509294934855 1.0 0.2572402077069448 43 Q9BZG1,P08670,P50570,Q03518,P51790,Q6WKZ4,Q9Y487,Q06481,Q93050,P04439,P10321 11 +Ribbon synapse 0.5813608976636897 1.7139526665890332 0.0865374192977828 1.0 0.2581699675717187 3 P56545 1 +Vacuole 0.3412444880897964 1.680252212022735 0.0929082546068413 1.0 0.2744319731786239 201 Q13614,P42785,Q8NHP8,Q15165,O15118,Q9HC07,Q14108,P50897,P04114,P42892,Q5BJF2,Q8NHS3,P41440,Q16625,P07437,Q6IQ22,Q8NCC3,Q9Y487,O14773,Q9UMR5,Q9NX40,P54802,Q9UHG3,Q9UIQ6,O75503,Q9UM22,P27105,Q96EE3,Q8WTV0,Q8TBX8,P38435,Q9NQX7,Q96RL7,P07948,P60520,P51790,P20645,O15400,Q93050 39 +External side of plasma membrane 0.5135049186329034 1.6772365300265522 0.0934962383438302 1.0 0.2752603069662108 23 P41440,P42892,P08183 3 +Gtpase complex 0.6500221897321561 1.6710732744038057 0.0947072054849313 1.0 0.2779113078984052 5 P04899,Q14344 2 +Plasma membrane raft 0.5450751852669475 1.6580213541610045 0.0973131562953946 1.0 0.2846250813214973 19 P41440,P09601,Q8WTV0 3 +Clathrin coated endocytic vesicle membrane 0.5833365119683948 1.6535650677061375 0.0982159152456272 1.0 0.2857839138430544 15 P04114,P02786,Q14108,P11717 4 +Mcm complex 0.6817967649668069 1.6497865188299148 0.0989866070294378 1.0 0.2857839138430544 6 P33993,Q14566,P33991,P25205 4 +Neuron projection terminus 0.5817439931952464 1.6444626964894355 0.1000806636565641 1.0 0.2870903652968745 15 Q13641,P51790,Q9UQB8 3 +Basal part of cell 0.4204150432584181 1.6356298988982905 0.1019170689271269 1.0 0.2897382297346633 51 P42785,P30825,Q15758,P41440,P23634,Q96RT1,Q9Y6M7 7 +Early endosome membrane 0.471458641706697 1.629924690572934 0.1031174145790541 1.0 0.2920572343299158 35 Q13614,Q9BZF3,Q96J02,P51790,O15400,Q06481,Q9HC07,Q9H267 8 +Cytosolic region 0.6667566004670947 1.6169334533257076 0.1058926462949423 1.0 0.2980311900439414 7 Q9UQB8 1 +Nuclear inner membrane 0.538085428570302 1.6140337823066715 0.1065200988881223 1.0 0.2988573307362679 19 O75844,P20700,Q5JTV8,O94901,Q99720,P50402,P62995,Q03252,Q9H1E5 9 +Postsynaptic endosome 0.5617830969235226 1.609011474543187 0.1076138326110918 1.0 0.3009824380841474 3 P20338 1 +Lsm1 7 pat1 complex 0.6003868729581621 1.6008339364310569 0.1094137049394825 1.0 0.3027358690036357 4 P62310,Q9Y4Y9 2 +Cytoplasmic stress granule 0.4423457815757338 1.598053122036715 0.1100311551652486 1.0 0.3027358690036357 41 O95793,Q92879,Q9NR56,Q9UBU9,Q9HCE1,Q14011,P67809,Q15717,Q13310,P61978,Q14157,Q9NUL3,Q71RC2,P11940 14 +Respiratory chain complex iv 0.6456899953868046 1.5969795227708383 0.1102702718381958 1.0 0.3027358690036357 9 P09669,P13073,P14406 3 +Clathrin coated vesicle membrane 0.4978480504258747 1.556369429072897 0.1196202703718256 1.0 0.3192687312332396 22 P04114,P11717,Q14108,Q8NC96,P02786 5 +Organelle subcompartment 0.3020099077071595 1.5550340878276374 0.1199379511145701 1.0 0.3192687312332396 401 Q9BZF3,Q96PC5,Q8NBM4,Q6NUM9,Q99720,P30519,Q4J6C6,O75396,Q5BJF2,Q7Z2K6,Q9NPR9,Q9BRK0,P09601,P53367,O00461,Q8IY17,O60725,Q16850,P07099,O43731,Q9HD20,Q86YN1,P0CG08,Q9NZ08,O14653,Q5BJH7,P24390,Q53GQ0,Q13555,Q9BRR6,Q96HY6,P50570,Q5VV42,Q92575,Q9Y5P4,Q9P260,P48449,Q9Y2V7,P38435,Q96RL7,Q9BZG1,Q9Y282,Q10713,Q6PIU2,Q8NHH9,Q96G23,Q00765,P11717,Q9BTZ2,Q9HC07,Q14108,P04114,P84095,Q15392,P43307,Q86XL3,O43464,Q12981,O60762,O15126,P83436,Q03518,P60520,P51572,P20645,O43852,Q9NPA0,Q15800,Q8TDW0,Q8N0U8,P10321,Q9UHQ9,O95470,A1L0T0,Q13190,Q8WXH0,Q9Y2B2,P51571,Q9Y2G5,Q9UP83,Q9P2W9,Q92643,O75844,O75787,O60499,P26885,P04439 87 +Intrinsic component of mitochondrial inner membrane 0.4677261778005294 1.5442346515762764 0.122531497114209 1.0 0.3239093052783903 33 O43819,O60830,O95563,Q13505,Q9NX63,Q99595,Q5XKP0 7 +Extrinsic component of postsynaptic specialization membrane 0.5095438369459827 1.5349428629905324 0.1247978635694595 1.0 0.3285120232196067 2 P52292 1 +Endoplasmic reticulum palmitoyltransferase complex 0.5076027175671398 1.5237254316788909 0.1275773137609563 1.0 0.3319235343489999 2 O15270 1 +Palmitoyltransferase complex 0.5076027175671398 1.5237254316788909 0.1275773137609563 1.0 0.3319235343489999 2 O15270 1 +Mitotic spindle microtubule 0.6491704898930235 1.4993574073876232 0.1337809368739602 1.0 0.3450545778161221 6 Q9H6D7 1 +Exocytic vesicle 0.4391672216075662 1.495620630203458 0.1347525439626447 1.0 0.3465618587545029 39 Q13614,O43760,Q9UI14,P51790,Q6IQ22,Q9NRW7,O15400,Q9BT78,P50897,O15126 10 +Centrosome 0.3380687380330256 1.4887490819047842 0.1365534550385465 1.0 0.3491866921699976 137 Q9UJW0,Q00013,P36405,P50402,Q9NTK5,Q9Y5K8,Q13045,P41440,Q6DKK2,Q13416,Q13432,P25205,P28074,P04899,P50570,P55081,O94927,Q86UY6,Q96JB5,Q9NY27,P14635,Q9P287,Q13561,Q9H6D7,P53350,Q03518,Q9H814,Q9BSJ2,Q71F23,Q7Z6E9,Q8N1F7 31 +Transport vesicle 0.3719163186784096 1.4774635562128566 0.1395514203497236 1.0 0.3548253443551213 93 Q13614,P11717,O75396,O00429,P50897,O14653,P10321,P24390,Q6IQ22,Q13190,P30040,Q9UI14,Q9GZM5,O94979,O15126,O00461,O43760,O60664,P51790,P20645,Q9NRW7,O15400,Q9BT78,O60499,P04439,O43731 26 +Extrinsic component of postsynaptic membrane 0.5745466299527154 1.4692865235455916 0.14175509053281 1.0 0.3553804090388373 4 Q9Y4F1 1 +Chloride channel complex 0.6055801681039559 1.456131997088066 0.1453561337636624 1.0 0.361254118312408 5 Q9C0H2 1 +Phagocytic vesicle membrane 0.4745133292546807 1.4489468241570873 0.1473524333354068 1.0 0.3643105741303566 26 Q9BZG1,P50570,Q03518,Q6WKZ4,Q9Y487,Q06481,Q93050,P04439,P10321 9 +Specific granule membrane 0.5285266672513713 1.4371208419811905 0.1506836600632386 1.0 0.3644915560989151 17 Q6IAA8,Q4KMQ2,Q08722,Q9BXS5,P30519,P27105,Q9Y5K8,O15126 8 +Ccr4 not core complex 0.4917502426399254 1.4318023135126825 0.1522004049950582 1.0 0.3661209645274627 2 Q92600 1 +Ccr4 not complex 0.4917502426399254 1.4318023135126825 0.1522004049950582 1.0 0.3661209645274627 2 Q92600 1 +Schaffer collateral ca1 synapse 0.5419393860570092 1.4150551547721044 0.1570523253432503 1.0 0.373834657399492 15 Q9BVA1,P07196,Q9UQB8,Q15375 4 +Intrinsic component of plasma membrane 0.3763637490885912 1.409965280258239 0.1585499350991979 1.0 0.3759720051738893 79 Q8TDW0,P11717,O15118,Q9Y4G8,P02786,P10321,O60637,Q13641,P41440,P23634,Q9BRK0,Q08722,O43464,Q9UIQ6,Q15375,P27105,Q99808,Q8WTV0,P07948,P30825,Q15758,P51572,P51790,P20645 24 +Clathrin coated endocytic vesicle 0.5047349907866012 1.4023478061173351 0.1608114111849008 1.0 0.3792270493912392 19 P50570,P11717,Q14108,P04114,P02786 5 +Cytochrome complex 0.5288708682909569 1.387059536925737 0.1654236090393372 1.0 0.3845735692040559 16 P09669,Q7KZN9,P14406 3 +Cyclin dependent protein kinase holoenzyme complex 0.598658129527049 1.3654167579238994 0.1721220998021242 1.0 0.3980601532891503 9 Q9P287,P14635 2 +Tight junction 0.4664371531082075 1.3626932457774914 0.1729792073858416 1.0 0.3986991345340928 24 Q16625,Q9NR77,P16989 3 +Paraspeckles 0.6189315037584966 1.358613694564805 0.1742690333403316 1.0 0.3999250893322995 6 Q16630,Q15233,Q8WXF1 3 +Nuclear outer membrane 0.5855194132526773 1.3002274205293998 0.1935230352210653 1.0 0.4319279713786868 9 Q99720,Q8WXH0,Q6NUM9 3 +Neuron to neuron synapse 0.3793686405247302 1.2831778899398898 0.1994297602729371 1.0 0.4421103558963867 53 Q13614,P51991,P07948,P23396,P50570,Q99720,Q15375,Q9UEY8,Q9UQB8,P23634,P35611,O43815 12 +Prespliceosome 0.5742226730110673 1.2822064759454892 0.1997702250892825 1.0 0.4421103558963867 10 O75400 1 +Hops complex 0.499636987822717 1.270747513004809 0.2038184866531271 1.0 0.4453077532438987 3 Q9H267 1 +Outer membrane 0.3582174679898973 1.2702496119858155 0.2039957305363111 1.0 0.4453077532438987 90 Q6NUM9,Q9NS69,Q99720,P21796,P50402,Q9HCL2,Q9Y3D6,Q15388,Q8N4H5,Q7Z434,Q13505,Q5XKP0,P45880,O00264,O43169,Q8N0X7,Q8WXH0,Q9BX68,Q9BUK6,P09601,Q9NX63,Q13794,Q9H974,Q5VT66,Q96RL7,P50416 26 +Tubular endosome 0.4983818770226568 1.263860134140809 0.2062802328669055 1.0 0.448108758290972 3 Q9UNH7,O75436 2 +Magnesium dependent protein serine threonine phosphatase complex 0.5860743909136819 1.2344069253309464 0.2170513097322801 1.0 0.4680986077358813 7 Q9NY27,Q8TF05,P63151,P30154 4 +Mitochondrial protein containing complex 0.320713780436266 1.2263407034168063 0.2200704900818599 1.0 0.4700789704612522 169 Q9P0J0,Q567V2,O60830,Q9NS69,Q99595,P03886,P14406,O96000,P49406,P09669,Q8N4H5,Q15118,O95182,P60602,Q13505,Q5XKP0,Q9Y375,P13073,Q96IX5,P00846,P51970,Q96CU9,Q9Y584,P62072 24 +Chitosome 0.4883495145631117 1.2087714263938465 0.2267506719940319 1.0 0.4791253937157904 3 Q13637,Q04656 2 +Neuromuscular junction 0.5252340075931438 1.2047625537061883 0.2282949797341382 1.0 0.4791253937157904 13 P46939,O43760,Q15375,P35579,P07196 5 +Trans golgi network 0.3590841090992885 1.2040032656816932 0.2285883163314441 1.0 0.4791253937157904 61 P83436,P50570,Q9BXS5,P35670,Q9P260,P20645,Q4J6C6,P11717,O15127,Q9UP83,O60499,Q9HC07,Q9NPR9,Q9Y2V7,P53367,P40616,O15126 17 +Microtubule organizing center 0.3192498962318028 1.1986876058324216 0.2306494391539273 1.0 0.4823160000999181 167 Q9UJW0,Q00013,P36405,P50402,Q9NTK5,Q69YQ0,Q9Y5K8,Q13045,P41440,Q6DKK2,Q13416,P28070,Q13432,P38398,P25205,P28074,P04899,P08670,P50570,P55081,O94927,Q9UFC0,Q86UY6,Q96JB5,Q9NY27,P14635,Q9P287,Q13561,Q9H6D7,P53350,Q03518,Q9H814,Q14166,Q9BSJ2,Q71F23,Q7Z6E9,Q8N1F7,P06493 38 +Cell surface 0.3571847448728555 1.1711505920040617 0.2415382510809092 1.0 0.4965737761239328 75 O75787,Q13641,P17655,Q4KMQ2,Q08722,P41440,P51790,P11717,Q8WWI1,Q8WTV0,P08183,P42892,P02786,P04439,P10321,O43847 16 +Intrinsic component of mitochondrial membrane 0.3718385359564573 1.1595338762878618 0.2462386363145097 1.0 0.5031588573093292 51 O43819,O60830,O95563,P50416,Q13505,Q9NX63,Q99595,Q6P4A7,Q5XKP0 9 +Recycling endosome 0.4077036589655947 1.1417073276884124 0.2535756939264384 1.0 0.5111492028472125 36 Q9P260,P51790,Q6IQ22,Q6WKZ4,O15400,O14773,Q9H267,P02786,O15126 9 +Leading edge membrane 0.4032476428956123 1.1311270763584929 0.2580016094697872 1.0 0.5171759432086397 37 Q9BZG1,P50570,P23396,P31751,P51790,Q06481,P23634,Q8WXH0,Q92974 9 +Rna polymerase ii transcription repressor complex 0.4399870592041429 1.1290496330103597 0.2588768967122576 1.0 0.5171759432086397 2 P35222 1 +Female pronucleus 0.5072613188684474 1.122740928023592 0.2615475401290164 1.0 0.5194719911002329 4 P83916,O43823 2 +Lsm2 8 complex 0.5683351425077622 1.121512732150335 0.2620696750136273 1.0 0.5194719911002329 6 Q9UK45,P62310,Q9Y4Y9 3 +Brca1 a complex 0.4711172792571022 1.1140885359744463 0.2652412062503511 1.0 0.5194719911002329 3 Q9NXR7 1 +Endoplasmic reticulum golgi intermediate compartment membrane 0.4244232054740038 1.1130853450329408 0.2656717770892549 1.0 0.5194719911002329 28 Q5BJH7,Q03518,P24390,P51572,Q9Y282,Q13190,O14653 7 +Nuclear outer membrane endoplasmic reticulum membrane network 0.2794780334792545 1.1096453037495435 0.2671519009788601 1.0 0.5194719911002329 340 Q9BZF3,Q9HD20,Q8TDW0,Q96PC5,Q8NBM4,Q6NUM9,Q86YN1,Q99720,P30519,O75396,Q9BTZ2,Q9NZ08,Q8N0U8,Q14108,P04114,Q5BJF2,P84095,O14653,P10321,Q7Z2K6,Q5BJH7,P24390,Q9UHQ9,Q53GQ0,Q13555,Q15392,Q9BRR6,P43307,O95470,A1L0T0,Q13190,Q8WXH0,Q96HY6,Q9Y2B2,Q9BRK0,Q86XL3,Q5VV42,Q92575,Q9Y5P4,O43464,P09601,P48449,P51571,Q12981,Q9Y2G5,Q9P2W9,Q92643,P38435,O60762,Q9NPA0,Q96RL7,O75844,O75787,Q8IY17,Q03518,P60520,P51572,P04439,O60725,Q9Y282,O43852,P26885,Q6PIU2,Q16850,Q8NHH9,P07099,Q15800,Q96G23,O43731 69 +Microvillus membrane 0.5046940757526593 1.109479983465411 0.2672231747736884 1.0 0.5194719911002329 4 P35222,P15311,P06756 3 +Endosome membrane 0.3295330456174633 1.1070649977122224 0.2682658274686103 1.0 0.5194719911002329 110 Q13614,Q9BZF3,P11717,O15118,Q9HC07,Q14108,P04114,P42892,P02786,O14653,P10321,Q96AX1,Q6IQ22,Q9Y487,Q96J02,Q6IAA8,Q06481,O15126,O00461,Q96RL7,O75787,Q9UBB6,Q9H267,P51790,Q9NRW7,O15400,Q93050,P04439 28 +Presynaptic active zone 0.5074321977960716 1.1061082528267354 0.2686796670668494 1.0 0.5194719911002329 13 P41440 1 +Replisome 0.5394561835205542 1.1054875318072814 0.2689483940410997 1.0 0.5194719911002329 10 P49005 1 +Ruffle membrane 0.4285795051335298 1.1046644565825008 0.2693050101138992 1.0 0.5194719911002329 25 Q9BZG1,P50570,P23396,P31751,P51790,Q06481 6 +Integral component of synaptic vesicle membrane 0.5647392693135446 1.1046463623711378 0.2693128534866011 1.0 0.5194719911002329 6 O15126 1 +Membrane microdomain 0.3488283387475785 1.0962064411032535 0.2729884414897001 1.0 0.5232307246821171 60 P07948,P17655,P41440,P07437,P09601,P46108,P21796,O15118,P27105,P23634,P50897,Q9UJZ1,O14773,Q8WTV0,P04899 15 +Nadh dehydrogenase complex 0.423120299323251 1.0894886936859358 0.2759384380446472 1.0 0.5232307246821171 27 Q9P0J0,O95182,P51970,O75380,Q96CU9,O43678,Q9Y375,P03886,O96000 9 +Filopodium membrane 0.4987031817839371 1.078546631965646 0.2807898831016615 1.0 0.531304324262129 4 Q8WXH0 1 +Origin recognition complex 0.5504435186195717 1.0640626831940538 0.2873003043278785 1.0 0.5356953591113569 7 Q9UFC0,Q9Y619 2 +Apical junction complex 0.4143142264975388 1.052574347973041 0.292536119035256 1.0 0.5436443259782043 29 Q16625,Q9NR77,P16989 3 +Gamma tubulin complex 0.4598152765767259 1.0520463494973404 0.2927782850519491 1.0 0.5436443259782043 3 Q9BSJ2 1 +Eukaryotic translation initiation factor 2 complex 0.4576051779935319 1.0399274711390476 0.2983735984071414 1.0 0.5506069496379207 3 P05198,Q9BY44 2 +Outer mitochondrial membrane protein complex 0.4683445308055753 1.0257965204271968 0.3049875065727234 1.0 0.5524252363074227 16 Q5XKP0,Q8N4H5,Q13505,Q9NS69 4 +Coated vesicle membrane 0.3456253247760721 1.0145169719604297 0.3103361351402287 1.0 0.5543928961087918 56 P04114,P10321,Q13190,P24390,P20645,P11717,O75396,O15027,O94979,Q14108,Q8NC96,O43731,P02786,P04439,O14653 15 +Endoplasmic reticulum tubular network 0.4786102966558788 1.0078692598926875 0.3135172307710965 1.0 0.5556394485943196 14 Q00765,Q9BRK0,P50402,Q8NHH9,Q9C0E8 5 +Platelet alpha granule 0.462771322584922 0.9925856101701296 0.3209119401982203 1.0 0.5665013539988307 16 Q9UHQ9,Q8NBX0,Q8NBM8,Q06481,Q9NTK5,Q9H267 6 +Microtubule cytoskeleton 0.2685415148076747 0.9814178778600018 0.3263867134965506 1.0 0.57390198149197 299 Q9UJW0,Q96FZ7,Q9BXS6,Q16181,Q07866,P29372,Q99426,Q00013,Q14203,P36405,P50402,Q9BZK7,Q9NTK5,Q9BUF5,Q69YQ0,Q08J23,Q9Y5K8,Q53HL2,P52732,O95793,P83916,Q13045,P23396,P41440,Q6DKK2,P07437,Q13416,P28070,Q13432,P38398,Q9UQB8,P25205,P28074,P04899,Q92974,Q9BTE7,Q9NVJ2,Q9BRK0,P08670,Q96TC7,P50570,P55081,O94927,Q9UFC0,Q86UY6,Q03001,Q9UJX3,Q96JB5,Q9NY27,P14635,Q9P287,Q13561,Q9H6D7,Q8N163,P53350,Q03518,Q9H814,Q14166,Q9BSJ2,Q71F23,Q7Z6E9,Q8N1F7,Q9NUL3,Q9BVA1,Q9UQE7,O95816,P35579,P06493,Q96P70,O60566,Q96DB5 71 +Zymogen granule membrane 0.4774643894366237 0.9691566462717096 0.3324670382081101 1.0 0.582305282184459 4 O15126 1 +Protein kinase complex 0.4202086386868848 0.9606520762181792 0.3367271350749794 1.0 0.5872030921122737 21 P14635,P12956 2 +Cell projection membrane 0.3362784746405889 0.9596493557082388 0.3372317199393393 1.0 0.5872030921122737 60 Q9BZG1,O75787,P23396,P50570,P41440,P31751,P51790,Q06481,P23634,Q8WXH0,Q92974 11 +Distal axon 0.3525168501082422 0.9490324935154808 0.3426040861045361 1.0 0.5942454594255036 50 Q13641,P50570,Q99720,P51790,P80723 5 +Anchored component of synaptic vesicle membrane 0.4710262220783337 0.9361339765646288 0.3492042114220952 1.0 0.596446124470945 4 P20339,Q15286,P51149 3 +Proteasome complex 0.3586666320043343 0.9142262088838335 0.3605979952361737 1.0 0.6089343504459915 44 P49721,Q9UL46,Q99436,P20618,Q05086,P28070,P28074,Q92530 8 +Glial cell projection 0.4321527213577035 0.9009670765367248 0.3676058250723317 1.0 0.6184346117288287 3 Q06787 1 +Secretory granule membrane 0.3330841280376745 0.8897708469767376 0.3735889434379809 1.0 0.6249758960317624 74 P42785,O75787,Q6IAA8,Q4KMQ2,Q13576,Q9BXS5,Q08722,Q9UHQ9,P30519,P11717,Q06481,P27105,Q9NQX7,Q93050,Q9Y5K8,P84095,P10321,O15126 18 +Ubiquitin conjugating enzyme complex 0.4606668824862288 0.8831979565880884 0.3771293254619792 1.0 0.625396998993687 4 P61088,Q5VTR2,O75150 3 +Ciliary transition zone 0.5172092028253362 0.8828182060089178 0.3773345021861352 1.0 0.625396998993687 6 P36405,A6NIH7 2 +Specific granule 0.3818995145625546 0.8698932431894062 0.3843587483245994 1.0 0.6323549260119787 33 Q6IAA8,Q4KMQ2,Q08722,Q9BXS5,P30519,P51790,P27105,Q9Y5K8,O15126 9 +Endoplasmic reticulum lumen 0.3277175788554362 0.861576804395272 0.3889204398048398 1.0 0.6359055675079117 61 Q14257,Q32P28,O75718,Q9NWM8,Q8IXB1,O43852,Q06481,Q9NZ08,Q9UNW1,P04114,Q96AY3,P13674 12 +Golgi apparatus subcompartment 0.3283308202504406 0.851444558715725 0.3945224484146901 1.0 0.6414256216809536 83 O00461,P83436,Q9BZG1,P50570,Q9P260,P51572,Q4J6C6,P0CG08,P11717,Q9HC07,Q10713,Q9NPR9,Q9Y2V7,P53367,O15126 15 +Mitochondrion 0.2661421436525217 0.8494956978386096 0.3956055230926105 1.0 0.6414256216809536 647 Q9BWD1,Q567V2,O60830,Q70HW3,Q99595,P23786,Q69YU5,O43772,P03886,Q9H773,Q9NPH0,P30837,Q8N4H5,Q13011,Q9H061,Q9NR77,P60602,Q8NBX0,Q9UMX5,P28070,O95831,P22830,P00846,O95563,P09601,Q96CU9,P52888,Q9Y584,Q13794,Q8TBP6,Q86VD7,P48735,Q7KZN9,Q9Y619,Q9H6K4,P62072,Q96H78,Q9BQT8,Q9UDX5,Q15165,Q9HCL2,P14406,Q96AY3,Q08J23,P09669,P49748,Q15118,Q6DKK2,Q5XKP0,Q9Y375,Q9Y5P4,Q96RR1,Q9BYT8,Q9H974,P14635,Q5VT66,Q96RL7,Q8N163,Q13423,O43819,P50416,Q9H3P7,Q9P0S9,Q10713,Q9P0J0,Q9NS69,Q9BQP7,Q9BTZ2,O96000,P02786,P49406,Q9BUP0,O95182,Q13505,P13073,Q96IX5,P13674,O43464,P51970,Q9NX63,Q12981,P27105,O43823,P07948,P51572,O43847,Q7L8L6,Q5JRX3,P21796,Q96E11,Q6P4A7,Q8TD30,Q9UJZ1,Q3SXM5,Q9Y3D6,O75648,P17655,P23396,Q9UHQ9,Q96TA2,P45880,O96011,O43169,Q8N0X7,Q8WXH0,Q9BX68 106 +Rough endoplasmic reticulum 0.380922180225888 0.8454730627310021 0.3978467663942318 1.0 0.6438930486850587 32 Q5BJF2,Q9UQB8,P36578 3 +U6 snrnp 0.50028523086017 0.8262782804472039 0.4086462512940518 1.0 0.6578028685398856 7 Q9UK45,P62310,Q9Y4Y9 3 +Microtubule 0.3132549048460343 0.8224962424498657 0.4107945243617688 1.0 0.6600737869008673 106 Q96FZ7,Q9BXS6,Q07866,P29372,Q99426,Q14203,O00429,P36405,P50402,Q9BUF5,P52732,P07437,Q9UQB8,Q92974,Q9BRK0,Q96TC7,P50570,O94927,Q03001,Q96JB5,Q13561,Q9H6D7,P53350,Q9BSJ2,Q9NUL3,Q9BVA1,O95816,P06493,Q96DB5 29 +Dendritic tree 0.3199819806335667 0.8131735171670597 0.4161185807994936 1.0 0.6663519198466833 94 Q13614,Q9Y4F1,P50897,O43815,Q99729,O95793,Q13641,P17655,Q12955,O75494,P98179,Q9UQB8,P23634,P04899,P12814,Q15375,Q06787,P51114,Q13277,Q9BPU6,Q9Y5S9,Q9P265,O75787,Q9UBB6,Q9NUL3,O95816,P21964 27 +Membrane protein complex 0.2596481163051848 0.8042146480929303 0.4212730205469686 1.0 0.670888529162877 292 Q8TDW0,Q9P0J0,O60830,Q9NS69,O75380,P21796,P11717,Q99595,O75396,P03886,P14406,Q8NC96,O96000,P02786,Q9Y5K8,P09669,O14653,P10321,Q15388,Q8N4H5,O00459,P55196,O95182,P41440,Q53GQ0,P60602,Q13505,Q96AX1,Q5XKP0,P62993,Q9Y487,O75964,Q9Y375,P45880,O43676,O60749,P13073,Q96IX5,Q13190,P04899,Q8WXH0,Q9C0H2,Q6IAA8,Q4KMQ2,P00846,O43464,P51970,O94901,P00403,Q9NX63,P51571,O94979,Q96CU9,P21912,Q9Y584,Q12981,Q9P2W9,Q92643,P07948,O75787,P46939,Q03518,Q9H267,O15400,Q9Y2T2,O60499,P62072,Q9NPA0,Q93050,O43678,P04439 71 +Mhc class i peptide loading complex 0.4700493282514435 0.7933872319506609 0.4275522473841053 1.0 0.6784738677460537 5 Q03518 1 +Dna polymerase complex 0.4493061845851365 0.7867985598171643 0.431399796709085 1.0 0.6833678195657188 13 P25205,P49005 2 +Sarcoplasmic reticulum membrane 0.4807693530993803 0.7819544334274952 0.4342413531490598 1.0 0.6853107512430877 9 Q8WXH0,Q13555,Q13586 3 +Aryl hydrocarbon receptor complex 0.3788417987706333 0.7740976407033966 0.4388730525771205 1.0 0.6899304429196108 2 P08238 1 +Ruffle 0.342771132429964 0.7698507231609828 0.4413884472292317 1.0 0.6899304429196108 44 Q9BZG1,P50570,P23396,P31751,P51790,Q06481,Q10713,Q9UQB8 8 +Synaptic vesicle membrane 0.4307468711491526 0.7690786094716631 0.4418466457336643 1.0 0.6899304429196108 15 O43760,O60499,O15126 3 +Basolateral plasma membrane 0.3425672838191564 0.7680112018551447 0.4424805298724654 1.0 0.6899304429196108 44 P30825,P41440,P23634,Q96RT1,Q9Y6M7 5 +Platelet alpha granule lumen 0.4644919165674952 0.7290409076232713 0.4659766396256617 1.0 0.7178125515748145 10 Q8NBX0 1 +Cop9 signalosome 0.4739502367998127 0.7252395901113008 0.4683050588973345 1.0 0.720159841431468 8 Q99627,Q9BT78 2 +Crd mediated mrna stability complex 0.482193830514991 0.7225754905592827 0.4699407306281007 1.0 0.7214355984771014 6 P67809 1 +Neuron spine 0.3710129323213979 0.7112053193728061 0.4769570127558462 1.0 0.7259804871028612 27 Q13614,Q9Y4F1,O75787,P12814,P51114,P23634,Q9UQB8,O43815 8 +Cell leading edge 0.3101298656551665 0.7082579859275895 0.4787850627157779 1.0 0.7262925951366462 98 Q13576,P23396,P41440,Q16625,P35241,Q9UQB8,O60749,P23634,Q8WXH0,Q92974,P08670,P50570,Q06481,Q03001,P35580,Q9BZG1,O75787,P31751,Q92538,P51790,Q10713,P11940 22 +Protein lipid complex 0.4737995500661935 0.6848695502892072 0.49342624216855 1.0 0.7422125827577349 6 Q9UHG3 1 +Synaptonemal structure 0.4599428985456936 0.681971616420005 0.495256898654788 1.0 0.7437163159329452 9 Q9UQE7,Q92791,P38398,P53350 4 +Nuclear exosome rnase complex 0.4527666588495068 0.6718972296171509 0.5016491241944601 1.0 0.7458072527475778 10 Q96B26,Q5RKV6,Q9Y3B2,Q9NQT5 4 +Endosome lumen 0.4400317529722996 0.6515847856912025 0.5146690651642893 1.0 0.7573454029949367 5 Q9UIQ6 1 +Plasma membrane region 0.2864898608760791 0.6474373412373834 0.5173489351284646 1.0 0.7590611425245506 173 Q13614,Q9Y4F1,Q16181,Q99720,Q9Y4G8,Q8NC96,P02786,P23396,P41440,Q16625,Q8WWI1,P35241,Q9UQB8,P23634,Q8WXH0,Q9Y6M7,Q92974,P50570,P09601,Q15375,Q06481,Q99808,Q8WTV0,Q96D71,P35580,P08183,P33527,P30825,Q9BZG1,Q15758,O75787,P31751,P51790,Q96RT1 34 +Endopeptidase complex 0.3190276463199405 0.6412221439350854 0.5213783644890153 1.0 0.7599896355336623 51 P49721,P17655,Q9UL46,Q99436,P28072,O43464,P20618,Q05086,P28070,O00231,P28074,Q92530 12 +Cd95 death inducing signaling complex 0.3542542866386223 0.6363712074979405 0.5245345028311044 1.0 0.7633469594046153 2 Q9UNN5 1 +Exon exon junction complex 0.4101331169973454 0.6310848035119657 0.527985076841432 1.0 0.7643338911835122 4 Q9Y5S9 1 +Proton transporting two sector atpase complex proton transporting domain 0.4263042505561333 0.6196739870964214 0.5354724450653667 1.0 0.7704949169348926 12 Q93050,Q9Y487,O75787,P00846 4 +Zymogen granule 0.4294298709728605 0.6027352644814836 0.5466848179574249 1.0 0.7828526593150325 5 O15126 1 +Meiotic cohesin complex 0.3985108449336206 0.5753308282092714 0.5650675758796053 1.0 0.7971934273027541 4 Q8N3U4,Q9UQE7,Q14683 3 +Intrinsic component of synaptic vesicle membrane 0.4311382056150219 0.5687623998121065 0.5695173946454459 1.0 0.800185350404512 10 O15126 1 +Risc loading complex 0.3377547719184717 0.5470967598167158 0.584312258217031 1.0 0.8095347849911242 2 O75569 1 +Nuclear stress granule 0.3377547719184645 0.5470967598166776 0.5843122582170572 1.0 0.8095347849911242 2 Q92797 1 +Sperm midpiece 0.4089083392075187 0.5106275451436865 0.6096118842360461 1.0 0.8286742734073516 5 Q96RL7 1 +Filopodium 0.3384401644384548 0.4807552892472176 0.6306904306326129 1.0 0.8470644761910896 26 Q9Y4F1,P46939,Q13576,Q06787,P51114,P35241,Q9UQB8,Q8WXH0,Q8IZP0 9 +Nuclear pore central transport channel 0.3508090614886766 0.4786011154067988 0.6322224246878747 1.0 0.8470644761910896 3 Q7Z3B4,P37198 2 +Protein phosphatase type 2a complex 0.4001685713083277 0.4725631526692233 0.6365248760682798 1.0 0.8502832299718066 5 P30154,P63151 2 +Cohesin complex 0.3986398963730548 0.4659858849679152 0.6412256039769848 1.0 0.8527443024656781 5 Q8WVM7,Q9UQE7,Q8N3U4,Q14683 4 +Transport vesicle membrane 0.3084177616897779 0.4610955909538283 0.6447300248723185 1.0 0.8551147936651876 43 O43760,O94979,O00429,O75396,O60499,Q13190,O14653,P04439,P10321,O15126 10 +Proton transporting v type atpase complex 0.393932391068695 0.4608322270742884 0.6449189784625717 1.0 0.8551147936651876 12 O75787,Q9Y487,Q93050,Q9Y5K8,Q8N511 5 +Cul2 ring ubiquitin ligase complex 0.3966639576841322 0.4575214627717582 0.6472962791267887 1.0 0.8562745479471335 5 Q13617,Q92990,Q8N668 3 +Lateral element 0.3728893599504144 0.4569321020216662 0.6477198491928846 1.0 0.8562745479471335 4 Q9UQE7 1 +Replication fork 0.3215453741466326 0.4387893496447985 0.6608141781360155 1.0 0.8599869323911871 35 P41440,P49005,P25205 3 +Copi coated vesicle membrane 0.3817792689140609 0.4379102987484792 0.6614513096774317 1.0 0.8599869323911871 13 O43731 1 +Podosome 0.4061588920317742 0.4371895250772644 0.6619739057540346 1.0 0.8599869323911871 9 P61978 1 +Copi coated vesicle 0.3739114307465629 0.4370256954398462 0.6620927132148755 1.0 0.8599869323911871 14 O43731 1 +Somatodendritic compartment 0.271916162421444 0.4360561903618862 0.6627959617262722 1.0 0.8599869323911871 122 Q13614,Q9Y4F1,Q14203,Q9Y4G8,P50897,P04114,O43815,Q99729,O95793,Q13641,P17655,Q12955,O75494,P98179,O00264,Q9UQB8,P23634,P04899,P12814,Q15375,Q06787,P51114,Q13277,Q9BPU6,Q9Y5S9,Q9P265,O75787,Q9UBB6,Q9H814,Q9NUL3,Q9UKA9,O95816,P21964 33 +Synaptic membrane 0.3174461559212899 0.4357657646620365 0.6630066853071721 1.0 0.8599869323911871 37 Q13614,Q99720,P51790,P23634,Q9UQB8 5 +Amphisome membrane 0.3368932038834999 0.4129306965549525 0.6796573902084464 1.0 0.8714804645222917 3 O43633,Q96FZ7 2 +Amphisome 0.3368932038834999 0.4129306965549525 0.6796573902084464 1.0 0.8714804645222917 3 O43633,Q96FZ7 2 +Escrt iii complex 0.3368932038834999 0.4129306965549525 0.6796573902084464 1.0 0.8714804645222917 3 O43633,Q96FZ7 2 +Endoplasmic reticulum exit site 0.3393849086002635 0.4050560537105739 0.6854363086014916 1.0 0.8755669222620795 20 Q96PC5,O94979,P04114,Q92734,P04439 5 +Filopodium tip 0.3837400871023329 0.4032592463740324 0.6867575189139439 1.0 0.8755669222620795 5 Q06787,Q8IZP0 2 +Nuclear inclusion body 0.3989330657337351 0.3923975657575002 0.6947644843693443 1.0 0.8816620100843743 8 Q86U42 1 +Micos complex 0.3803398122243651 0.3893212440545111 0.6970385230544269 1.0 0.8816620100843743 5 Q5XKP0 1 +Granular component 0.3573972159274715 0.3891038169437577 0.6971993500330413 1.0 0.8816620100843743 4 Q9NXV6,Q14684,O75683 3 +Recycling endosome membrane 0.3274663779169373 0.3682689838099131 0.7126726772221863 1.0 0.8971055500898126 21 Q6IQ22,O15127,P02786,P04439,P10321,O15126 6 +Microbody 0.2799799839627343 0.3651658776464858 0.7149875878037804 1.0 0.8978491982714621 60 O15254,Q9UBQ7,P48735,P08670,Q13011,Q9NR77,Q96CN7,Q9BTZ2,O96011,Q9Y3D6,Q8N4Q0 11 +Proton transporting two sector atpase complex 0.3192114294276501 0.3554220556322745 0.7222734280948642 1.0 0.90194255733913 25 O75787,Q93050,P00846,Q9Y487,O75964,Q96IX5,Q9Y5K8,Q8N511 8 +Nuclear replication fork 0.3492440256594908 0.3550370929160755 0.7225618029186103 1.0 0.90194255733913 16 P25205,P49005 2 +Side of membrane 0.2808879537909487 0.3479960135210924 0.7278431773608709 1.0 0.9060078494269532 64 P07948,Q9Y4F1,O75787,P17655,P41440,O43464,P51572,P51790,P08183,P42892,P02786,P04899,P10321 13 +Eukaryotic translation initiation factor 2b complex 0.3467141469731241 0.3443322126733082 0.7305964615508598 1.0 0.906814250017743 4 Q14232,P05198,Q9NR50 3 +U1 snrnp 0.3673097826237582 0.3394760916259074 0.7342511049961129 1.0 0.906814250017743 12 O75400 1 +Lamellipodium 0.2861667025406033 0.3372310603298159 0.7359427244919754 1.0 0.906814250017743 51 P11940,P50570,Q13576,P41440,P35241,Q9UQB8,Q8WXH0,P35580 8 +Tertiary granule 0.292589347136811 0.331980959343394 0.7399036366769358 1.0 0.908386494960024 43 P42785,Q6IAA8,Q4KMQ2,Q08722,P09960,O15400,P27105,Q93050 8 +Exoribonuclease complex 0.3459963089191928 0.3202646485292842 0.7487677193078568 1.0 0.918009738055523 15 Q96B26,Q9Y3B2,Q99547 3 +Prefoldin complex 0.3393479076841551 0.3145254236049186 0.7531220102366734 1.0 0.9181066160084056 4 O60925 1 +Vcp npl4 ufd1 aaa atpase complex 0.3392683716412956 0.3142086035401232 0.753362608678604 1.0 0.9181066160084056 4 Q96CS3,Q92890,Q9UNN5 3 +Golgi cisterna 0.3274813272697449 0.3124239215164306 0.7547183728355897 1.0 0.9181066160084056 19 O00461,Q9BZG1,Q10713,P0CG08 4 +Neuron projection membrane 0.3737507639289567 0.2850446404386264 0.7756099417784355 1.0 0.9338551039211306 7 P23634 1 +Rna polymerase ii core complex 0.3736228127025306 0.284583040390928 0.7759636060210551 1.0 0.9338551039211306 7 P19387,P62875,P30876,O15514,P24928,P19388 6 +Nuclear pore outer ring 0.3701575393440693 0.2805294761240133 0.7790713142722487 1.0 0.9343815162992576 8 Q96EE3 1 +Mitochondria associated endoplasmic reticulum membrane 0.3588969819165696 0.2794894079002637 0.7798692655592685 1.0 0.9343815162992576 11 Q15388,P51572 2 +Cluster of actin based cell projections 0.3022464043346753 0.2723742232363221 0.7853342905829133 1.0 0.9371655867622763 31 P41440,Q13045,Q9Y6M7 3 +Spliceosomal complex 0.2598398972458771 0.260408345094381 0.7945488065019255 1.0 0.9431315408743016 125 P09661,P52597,Q6NZY4,P61978,P62310,P62995,Q9NQ29,Q9Y312,Q86V81,O43390,P51991,Q9Y4Y9,P67809,Q13573,Q8IWZ8,O43395,P98179,O75940,P07910,P38159,O75400,Q9UK45,P31942,Q14011,Q8WWY3,Q96DF8,P55081,Q96E39,Q9Y5S9,O43290,Q9UKA9,O60506,P11940 33 +Vesicle tethering complex 0.3058906006372061 0.2498988398905865 0.8026655804012617 1.0 0.9505411079298546 21 P83436,Q9Y2D4,Q96AX1,Q9Y2V7,Q9H267 5 +Lumenal side of endoplasmic reticulum membrane 0.3642185860265591 0.2452643060174327 0.80625178746884 1.0 0.9505411079298546 6 P51572,P10321 2 +Photoreceptor connecting cilium 0.3208875961822197 0.2440870538246176 0.8071633989125022 1.0 0.9505411079298546 4 Q15019,P36405 2 +Xy body 0.319844609906112 0.2403027795884233 0.8100955403377861 1.0 0.9527404843657272 4 P16104,Q12824,Q92922 3 +Peptidase complex 0.264635526276028 0.2251674627952191 0.8218490004466206 1.0 0.9592455026226798 59 P49721,Q9UL46,Q99436,P20618,Q05086,P28070,O00231,P28074,Q92530 9 +Ficolin 1 rich granule 0.2746501658103312 0.220199219963914 0.825716004099057 1.0 0.9597608099592936 83 P42785,Q99436,P12956,P20618,Q93050 5 +Chromocenter 0.3538358042083302 0.2163625844041428 0.8287051288328213 1.0 0.9619858499421208 7 Q06787,P83916,P45973,Q53HL2 4 +Actomyosin 0.2947881227437328 0.2147332812148636 0.8299752731357817 1.0 0.9620736269157024 26 Q9UJW0,P35580,Q15942,P12814,P67936,Q16181,P35579,O95817,O00151 9 +Mib complex 0.3440995887915256 0.2054093619660684 0.8372523064355522 1.0 0.964505928008978 10 Q5XKP0,Q13505 2 +Septin cytoskeleton 0.3301702977458269 0.2039109638101298 0.8384230772036303 1.0 0.964505928008978 5 Q15019,Q16181 2 +Zona pellucida receptor complex 0.3299870466321221 0.2033138026344951 0.8388897678845408 1.0 0.964505928008978 5 P78371,P17987,P50990,P50991 4 +Copii coated er to golgi transport vesicle 0.2873902558987223 0.1977691699019892 0.8432256685675872 1.0 0.96642848221331 34 Q5BJH7,O94979,O75396,Q9Y282,Q13190,O14653,P04439,P10321 8 +Endoplasmic reticulum golgi intermediate compartment 0.269117545904428 0.1857907849826603 0.8526088312375382 1.0 0.9725239775089708 50 Q9BS26,Q5BJH7,Q99653,Q03518,P24390,Q8N511,P51572,Q92538,O75396,O95070,Q9Y282,Q13190,P80303,O14653 14 +Brush border 0.2890734528870621 0.1852972550700588 0.8529958908877564 1.0 0.9725239775089708 28 Q13045 1 +Sarcoplasm 0.3000743431893616 0.1793323067545102 0.8576767808996568 1.0 0.9726633029750102 19 Q13586,Q12955,Q13555,O43852,Q8WXH0,P28161 6 +Ciliary membrane 0.3430515063168161 0.1782177558958903 0.8585519657544782 1.0 0.9726633029750102 6 Q9H4M9,Q96J42,Q15019,P06744,O14936 5 +Pronucleus 0.3214105661040155 0.1761062752848491 0.8602104510120208 1.0 0.973070692562062 5 P83916,O43823 2 +Oxidoreductase complex 0.2643268932259087 0.173897311694665 0.8619461653975198 1.0 0.973070692562062 66 Q9P0J0,Q15118,O95182,P51970,P31350,O75380,Q96CU9,O43678,Q9Y375,P03886,O43676,O43169,O96000,P13674,Q5VT66 15 +Microtubule associated complex 0.2778709082471123 0.169018422746212 0.8657821506174663 1.0 0.9746855657894746 38 Q9UJW0,O95793,Q07866,O94927,Q96P70,Q9H6D7,Q13561,Q53HL2,P52732 9 +Synapse 0.2522056707263314 0.1658338073460467 0.8682877400590536 1.0 0.976278300694539 228 Q13614,Q9Y4F1,Q99720,Q9Y4G8,P50897,P51991,O95793,Q13641,P23396,P41440,Q9NR77,Q6IQ22,Q13432,Q9UQB8,P23634,Q8N0X7,P04899,P50570,Q9UI14,Q96F07,P63151,Q15375,Q99808,P05771,O15126,P07948,O75787,P46939,O43760,Q9UBB6,P51790,Q9NRW7,O15400,Q9UEY8,Q9BT78,Q96RT1,P07196 37 +Hippocampal mossy fiber to ca3 synapse 0.2945937196503669 0.1557556590969046 0.8762256228758682 1.0 0.9820109175308676 4 Q15375,P47756,O60716 3 +Chaperonin containing t complex 0.3303079416531709 0.1478796361302752 0.8824377595085999 1.0 0.9820109175308676 8 P50991,Q99832,P17987,P48643,P40227,P78371,P50990 7 +Er to golgi transport vesicle membrane 0.2809806468483844 0.1468363198030071 0.8832612163266462 1.0 0.9820109175308676 23 O94979,O75396,Q13190,O14653,P04439,P10321 6 +T tubule 0.328921481871298 0.1438065775028891 0.8856532087717432 1.0 0.9834486623457942 8 Q12955,P35241,P23634 3 +Tertiary granule membrane 0.3161222617922875 0.1410372838602526 0.8878404884510553 1.0 0.9846558081334504 12 P27105,Q4KMQ2,Q08722 3 +Main axon 0.2859983452671769 0.1302801018887557 0.8963448222813861 1.0 0.9858517486261228 4 Q9Y2J2,Q12955 2 +Epsilon dna polymerase complex 0.3056994818652829 0.1301840334479546 0.8964208265354863 1.0 0.9858517486261228 5 Q9NR33,Q9NRF9,Q07864,Q9NRG0 4 +Emc complex 0.3253190925755315 0.128293755360619 0.8979165067695953 1.0 0.9858517486261228 6 Q9NPA0 1 +Golgi associated vesicle membrane 0.2910426037632555 0.126339292384976 0.8994633546040913 1.0 0.9858517486261228 18 O43731 1 +Ribonucleoprotein granule 0.2646228551523927 0.1262197905212232 0.8995579460788325 1.0 0.9858517486261228 98 Q96C86,Q9UBU9,Q9HBH5,Q7L8L6,P62310,P61978,P42694,Q71RC2,Q08J23,P51991,P60900,Q99729,Q9NR56,Q9HCE1,O95793,P67809,P07437,P62312,Q9Y3Y2,Q92879,Q15717,Q14011,Q13310,Q14157,Q06787,P51114,Q9NUL3,P82979,Q07065,Q92797,P11940 31 +Beta catenin destruction complex 0.2829394626092511 0.1216415403298102 0.9031829133272696 1.0 0.9868917582588272 4 P35222,P48729,Q9HB71 3 +Clathrin coated pit 0.2790137132429321 0.1212095803172565 0.903525036072472 1.0 0.9868917582588272 21 Q8NC96,P02786,P50570 3 +Proton transporting atp synthase complex 0.2994780679676078 0.1019808116612084 0.9187719057427824 1.0 0.9967283098664124 13 P00846 1 +Organelle membrane contact site 0.2851275695502027 0.0928566755556032 0.9260174248771378 1.0 1.0 17 Q15388,P51572,Q96TC7,Q5XKP0 4 +Transcription factor tfiiic complex 0.288746376384129 0.0866320333706989 0.9309640026660972 1.0 1.0 5 Q9Y5Q8 1 +Rna polymerase iii transcription regulator complex 0.288746376384129 0.0866320333706989 0.9309640026660972 1.0 1.0 5 Q9Y5Q8 1 +Supramolecular complex 0.2326266530385685 0.06804805111388 0.9457473836445044 1.0 1.0 322 Q9UJW0,Q07866,P29372,P28289,P36405,P50402,Q69YQ0,Q96DY7,P60900,Q9UQB8,Q9BRK0,Q96TC7,P55081,P51114,Q03001,Q9H6D7,P53350,Q71F23,Q9BVA1,P35579,P06493,O60566,O00151,Q96FZ7,Q96C86,Q9UBU9,Q9BXS6,Q99426,Q14203,O00429,Q08J23,Q99729,Q9NR56,Q9HCE1,Q13586,P67809,Q12955,O75298,P62312,P23634,Q9NYL9,Q15717,Q14011,P08670,P50570,P12814,Q13310,Q06787,Q96EE3,P14635,Q9BZD4,O43819,Q15019,O60313,P11166,P82979,Q07065,P78371,Q96DB5,Q92797,Q16181,Q9HBH5,Q9Y266,Q6P1K2,P61978,P42694,Q9Y5K6,O75347,P05198,P09493,P67936,P07437,P14649,O95817,Q9Y3Y2,Q92879,O94927,Q9UFC0,Q96IY1,P57740,P07196,Q7L8L6,P62310,Q71RC2,Q9BUF5,P52732,P51991,O95793,P20700,Q13416,Q8WXH0,Q92974,Q14157,Q96JB5,Q13561,Q03252,P35580,Q9BSJ2,Q9NUL3,O95816,P11940 101 +Clathrin coat 0.2791465813915459 0.058778752830055 0.9531283319804388 1.0 1.0 15 Q8NC96,P11717 2 +Kinetochore microtubule 0.2905733722060217 0.048536507692312 0.9612886697841608 1.0 1.0 6 Q96FZ7,Q8WUX9,O43264,O43633,Q7Z460 5 +Microbody lumen 0.2557147655483155 0.0423388801023449 0.9662285512208896 1.0 1.0 22 O15254,Q9UBQ7,Q13011,O00116,Q9BTZ2,Q08426,O14734 7 +Condensed nuclear chromosome 0.2578635550278869 0.0378500799343459 0.9698072149416191 1.0 1.0 21 Q92791,P53350,Q9UQE7,Q9UEY8,P38398 5 +Ciliary plasm 0.2817284875143874 0.034771689796613 0.9722617952446287 1.0 1.0 11 Q10713 1 +Spindle microtubule 0.2575492843840859 0.0304813671359214 0.97568315334778 1.0 1.0 30 Q96TC7,P53350,O94927,P36405,P06493,Q96DB5,Q9H6D7,P52732 8 +Cytoplasmic exosome rnase complex 0.2787160915712987 0.0280788954659627 0.977599226414618 1.0 1.0 11 Q96B26,Q5RKV6,Q9NQT5 3 +Sarcolemma 0.2518766945207589 0.020564653751838 0.9835929367194408 1.0 1.0 24 P41440,P23634 2 +Blood microparticle 0.2587294146151496 0.0157248434795767 0.9874539072155974 1.0 1.0 18 P02786,P38435 2 +Spindle pole 0.2457891976823025 0.0085481709282869 0.9931796294554568 1.0 1.0 44 Q9UJW0,Q96TC7,P53350,Q9BSJ2,Q9UQE7,P50402,Q13432,Q9P287,P14635,Q96DB5,P52732 11 +Site of polarized growth 0.2467853016895886 0.0084003943973498 0.9932975338341964 1.0 1.0 41 P50570,Q99720,Q07866,Q06787,P51114,Q9UKA9,P80723,Q13561,Q8IZP0,P07196 10 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..174c51b29b8400dac47d5b310d174a4a74f5b2ec --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atp binding cassette abc transporter complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Calyx of held", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Chylomicron", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna recombinase mediator complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Muscle myosin complex", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class i", "Phosphatidylinositol 3 kinase complex class ia", "Phosphatidylinositol 3 kinase complex class iii", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Serine type endopeptidase complex", "Serine type peptidase complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilium bundle", "Stereocilium membrane", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquinone biosynthesis complex", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPGK", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C12orf73", "C14orf2", "C17orf75", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C3orf58", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARS2", "CASK", "CAST", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC22", "CCDC47", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPI", "CENPL", "CENPP", "CENPQ", "CENPU", "CENPV", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CISD3", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLTB", "CLTC", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP3", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM162A", "FAM207A", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP4", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMC1", "FMR1", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCX", "GGH", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD5", "HDLBP", "HEATR1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN2", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOXD11", "HP1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ISCU", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "IVD", "JAGN1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LETMD1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "M6PR", "MACF1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL7B", "METTL9", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD8", "MGAT1", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NEPRO", "NES", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPM1", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C3A", "NTHL1", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT12", "NUDT19", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAK1IP1", "PAK4", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PECR", "PEDS1", "PEF1", "PELP1", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHIP", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRSS3", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPS1", "ROMO1", "RP2", "RPA1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSRC1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT2", "SIGMAR1", "SIN3A", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35A4", "SLC35B2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPNS1", "SPOP", "SPOUT1", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TKT", "TLE3", "TLN1", "TM7SF2", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM214", "TMEM223", "TMEM230", "TMEM33", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBIAD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "USMG5", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H13", "ZC3H14", "ZC3H18", "ZC3H8", "ZC3HC1", "ZCCHC17", "ZCCHC8", "ZDHHC20", "ZEB2", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF148", "ZNF326", "ZNF346", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["AAR2", "ABCB1", "ABCC1", "ABI1", "ACADVL", "ACAT2", "ACBD3", "ACOT8", "ACOX3", "ACP6", "ACTN1", "ADD1", "ADD3", "ADPGK", "AFDN", "AGPS", "AIFM1", "AKAP8", "AKT2", "ALDH1B1", "ALYREF", "ANAPC7", "ANK3", "ANKLE2", "ANO6", "AP1M1", "AP3M1", "APLP2", "APOB", "ARFGAP1", "ARFIP1", "ARHGEF2", "ARL1", "ARL3", "ARL8B", "ASNA1", "ATL2", "ATP13A1", "ATP2B4", "ATP5L", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP7A", "ATP7B", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAIAP2", "BASP1", "BCAP31", "BCCIP", "BNIP1", "BRCA1", "BUB1B", "C12orf73", "C19orf70", "C3orf58", "CACYBP", "CALU", "CAMK2G", "CAPN2", "CAPZB", "CASK", "CBX1", "CBX5", "CCAR2", "CCDC134", "CCNB1", "CCT2", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD47", "CDCA8", "CDK1", "CDK5RAP3", "CDKAL1", "CDKN2AIP", "CELF1", "CENPU", "CERS2", "CHCHD3", "CHMP2A", "CHMP6", "CHMP7", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIRBP", "CKAP4", "CLASP1", "CLCN3", "CLN5", "CNOT9", "COG2", "COG5", "COG6", "COG7", "COL4A3BP", "COLEC12", "COMMD1", "COMT", "COPS4", "COPS8", "COX15", "COX2", "COX4I1", "COX6C", "COX7A2", "CPSF6", "CPT1A", "CPT2", "CRK", "CRTAP", "CSNK1A1", "CTBP2", "CTNNB1", "CTNND1", "CUL2", "CYB5B", "CYB5R1", "CYFIP1", "CYFIP2", "CYP51A1", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DCUN1D5", "DDRGK1", "DHCR24", "DHRS4", "DIP2B", "DNAJC10", "DNM1L", "DNM2", "DOLPP1", "DPM1", "DPYSL5", "DST", "ECE1", "ECH1", "EFHD1", "EHD1", "EHHADH", "EIF2A", "EIF2B1", "EIF2B3", "EIF2S1", "ELAVL1", "EMC7", "EMD", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "ERAP1", "ERBIN", "ERGIC3", "ERMP1", "ERP29", "ERP44", "ESS2", "EXOC6B", "EXOSC1", "EXOSC3", "EXOSC6", "EXOSC8", "EZR", "FAF1", "FAF2", "FAM3C", "FARP1", "FASTKD5", "FECH", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP9", "FLII", "FMR1", "FOXRED1", "FXR1", "GABARAPL2", "GALNT7", "GAPVD1", "GBF1", "GGCX", "GINS3", "GINS4", "GLG1", "GLMN", "GNA13", "GNAI2", "GOLGA5", "GOLIM4", "GOSR2", "GPAM", "GPI", "GPR107", "GPR108", "GPR89B", "GPT2", "GRB2", "GRHPR", "GSTM2", "GTF3C5", "H2AFX", "HAUS4", "HAUS5", "HELZ", "HINT2", "HLA-A", "HLA-C", "HMOX1", "HMOX2", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPF", "HNRNPH3", "HNRNPK", "HNRNPR", "HSD17B12", "HSDL1", "HSP90AA1", "HSP90AB1", "HTRA2", "ICMT", "IDH2", "IGF2R", "ILVBL", "IPO9", "IQGAP2", "ISOC1", "ITCH", "ITGAV", "ITM2C", "KDELR1", "KDELR3", "KIAA0319L", "KIAA1468", "KIF11", "KLC1", "KPNA2", "LAMTOR1", "LARP4", "LDAH", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LRRC8C", "LRWD1", "LSM3", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LYN", "M6PR", "MAN1A2", "MAN2A1", "MARC1", "MAVS", "MBNL1", "MCM3", "MCM4", "MCM6", "MCM7", "MFAP1", "MFSD8", "MGME1", "MIA2", "MINPP1", "MOV10", "MPC2", "MPG", "MPHOSPH6", "MPP1", "MPV17L2", "MRPL19", "MRRF", "MSMO1", "MSTO1", "MTBP", "MTFP1", "MTMR2", "MTX1", "MYH10", "MYH9", "MYL6B", "NAA40", "NAGLU", "NCDN", "NCEH1", "ND1", "NDUFA13", "NDUFA2", "NDUFA7", "NDUFA8", "NDUFAF1", "NDUFB10", "NDUFB3", "NDUFS6", "NECAP1", "NEDD4L", "NEFL", "NENF", "NLN", "NNT", "NONO", "NPC1", "NRDC", "NSL1", "NSUN2", "NUCB2", "NUDC", "NUF2", "NUP107", "NUP54", "NUP62", "NUP93", 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0000000000000000000000000000000000000000..e75977f185b8dd334b4df9b00399587bc128a30a --- /dev/null +++ b/msigdb_gomf/df_merge.tsv @@ -0,0 +1,46 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transporter activity 53 190 3.7756941701985496 0.0001595626704988 62.22330097087379 172.27912621359224 2.173366592838491 0.2707201784543502 25.984753572620328 19.29276868436311 2.593156143256053 0.3916539604106395 0.0003068482555216 0.0007089888835803 3.159881303904587e-05 3.193950833722375e-07 2.2895752482261976e-08 +Peptidase activity 33 105 3.1058691598854287 0.0018972064207205 29.021844660194176 113.626213592233 1.2572335980018865 0.3731282983707893 8.334453494010912 9.805689463637474 1.5136028692995414 0.3922229485757941 0.0014799249766011 0.0026017792618755 0.0001077218202972 2.7189312668959764e-05 1.5644785389819935e-06 +Ion transmembrane transporter activity 30 114 3.0514631082961885 0.0022772903142727 37.34466019417476 101.497572815534 2.0154097423383375 0.2561362875319209 17.172953606300336 11.579295798802024 2.277787478419462 0.3756175790939143 0.1488767778194473 0.186256583845972 0.0295213058069394 0.0001894557496079 9.190492268017762e-05 +Endopeptidase activity 22 56 2.908200171209114 0.0036351557272771 19.08495145631068 62.800970873786405 1.5604938505680932 0.2935756148549138 5.629332570724372 6.156865220927466 1.27979578418692 0.359984229645684 0.0344940938867227 0.0452685226123056 0.0052178109018932 0.0001941401036533 4.525258612641265e-06 +Anion transmembrane transporter activity 17 53 2.831767012652934 0.0046291565454394 18.594660194174757 45.61893203883495 1.6222323024349488 0.2373683627198559 9.346785472607134 6.017202751823004 1.8117646078257517 0.3183345645365742 0.422065399167455 0.4570575797650001 0.033005107755267 0.000235412956108 3.2406977549946285e-05 +Serine type carboxypeptidase activity 3 5 2.6644057384428166 0.0077124477605206 3.0558252427184467 4.997572815533981 1.0019911760482532 0.1105835516254352 1.1231414198895626 0.0492066381861973 1.8086551291944464 0.1930654928989846 0.0213958237580913 0.0238038053541035 0.0008973897437505 1.649417533450067e-06 2.5768870804533236e-05 +Tetrapyrrole binding 5 18 2.64562735407848 0.0081539587061414 7.402912621359223 16.83252427184466 2.0044897428967667 0.1259264696495541 2.9589081005845346 2.0417036568087963 1.3464702305086589 0.2177422235164347 0.0225977851626226 0.0276250495673642 0.0149914480702132 0.0018561414510811 0.0144870993594682 +Cation transmembrane transporter activity 16 79 2.5507599315217107 0.0107488337548808 25.62135922330097 70.51699029126213 1.766742880952279 0.2698419237572138 12.29126021871486 8.422243011776631 2.00238274385689 0.3706372466673562 0.2630357479278696 0.3052095683601886 0.1820864285977347 0.0014725426620442 0.0081518847742078 +Palmitoyltransferase activity 1 6 2.53948322394335 0.0111016369387582 1.8786407766990292 5.084951456310679 0.875863834441912 0.3421870647647222 1.2306088543936362 0.6827036113457149 1.018188317250868 0.2997914787323893 0.0789520148513954 0.0875404472016038 0.1677870330809631 0.0762921742488627 0.232790248880933 +Organic acid transmembrane transporter activity 7 23 2.5109488650661933 0.0120407136954634 8.592233009708737 21.276699029126213 1.5973629153049684 0.1905568538747131 4.4420473133518055 2.549726956007885 1.3213968531498468 0.2647933566957936 0.2555101444842079 0.2801168002074996 0.0275216398495969 0.0002231001666191 0.0051385782863233 +Serine hydrolase activity 9 21 2.50189377924099 0.012353098138893 6.934466019417476 18.83009708737864 1.2767207242593377 0.1489147276149277 2.386872767465543 1.965791668457755 1.709796217367629 0.2208345231085202 0.0181053013148336 0.0221752921752284 0.0108939889611676 0.0001418153943193 7.79127488810706e-05 +Exopeptidase activity 8 30 2.500764579299774 0.0123925527032116 9.74514563106796 31.84223300970874 1.193034763402526 0.2308543476384821 3.0338864063053523 1.9513159274241312 1.6646797512653713 0.2911825093455628 0.0022665329249465 0.003086924646434 0.0002876902013005 1.4349197272756235e-05 2.7913079286263463e-05 +Monooxygenase activity 3 8 2.4767586369493184 0.0132581526633546 4.043689320388349 8.322815533980583 1.6049222537693364 0.1501440468766332 1.612461779657682 1.2307404965531048 1.237349324058907 0.2369071661653372 0.1103417489787315 0.1221118561195742 0.0274603336438859 0.0038040834633598 0.0085681988325283 +Protein transporter activity 4 15 2.4503960968706235 0.0142699140657203 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 0.005126652342915 0.0063255491406275 0.0016986126979642 0.0028478177309091 0.0061038181966101 +Palmitoyl protein hydrolase activity 1 5 2.399237198024822 0.0164292683223754 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 1.0 1.0 0.1094892401774078 0.2550529546148332 0.1114297880404725 +Proline rich region binding 1 6 2.357291078108311 0.0184088107483491 1.1529126213592231 5.186893203883495 0.8836697013404169 0.3769016216180994 1.161024096877417 0.956085799787736 0.8816524975681769 0.2959695633458655 1.0 1.0 0.0100519320580488 0.0561137872346343 0.1789941624672536 +Proteasome binding 2 9 2.347369202125309 0.0189065100049214 2.9344660194174756 10.58980582524272 0.3784148328441568 0.5391220092078972 1.7853439081041342 1.2956959973836335 0.8542320107205437 0.3003434060811568 0.0669039716584752 0.0742352733278267 0.1432798584585485 0.0062267265321947 0.0391317335840731 +Metallopeptidase activity 13 37 2.3251287362144843 0.0200650774940955 11.548543689320388 40.60436893203884 1.2053444242445344 0.3510417366391842 4.586289489033314 2.1135899474190585 1.0988837346562612 0.3462572593421246 0.0048879575806257 0.0066118310835921 0.0001144472789083 0.0001286296435048 5.276742214439494e-06 +Serine type exopeptidase activity 4 7 2.320060876488238 0.0203375843833566 3.783980582524272 6.997572815533981 1.020609253431403 0.1137432544246352 1.3363606860118669 0.0492066381861973 1.87035730934538 0.1990592265121372 0.0381897723637082 0.0424464003246627 0.0031504918831051 9.327097249989188e-07 2.748807069516661e-05 +Threonine type endopeptidase activity 4 8 2.319902151640954 0.0203461711625909 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 1.0 1.0 0.0039135152062846 1.828578586842436e-06 2.1795177811063544e-06 +Metalloendopeptidase activity 7 14 2.284888268652788 0.0223193800927161 5.449029126213592 14.364077669902912 1.4597326207035937 0.2246869419023046 2.4848715129851016 0.6671711573432166 0.9390012824303952 0.2775881383017788 0.133195547841817 0.1471951297158956 0.0398064357050217 0.007920049564759 0.0001322973571325 +Snap receptor activity 8 15 2.2784760405550126 0.0226982304200911 5.803398058252427 13.6626213592233 0.8920027438628428 0.3386294703372389 3.103034547770364 2.9171839264116786 1.2201519782198902 0.3219991979242683 1.0 1.0 1.0 0.5661975770404395 0.005197217830129 +Inorganic anion transmembrane transporter activity 9 23 2.253633070239782 0.024219261092617 7.427184466019417 19.274271844660195 1.0921593405593897 0.2441056926448881 3.717191605498929 3.7816647851785734 1.4014196343960104 0.2816216967014333 1.0 1.0 0.3955810682553247 0.0367529115341812 0.0001584338115888 +Protein transmembrane transporter activity 3 12 2.2340645231447605 0.0254788278879845 4.37621359223301 11.264563106796116 1.6409152716253632 0.1284874270119089 2.3258190399954897 0.995332092405782 1.387057072324357 0.2266762256512647 0.002375523332682 0.0029386578360865 0.0005309775927247 0.0074273483269255 0.0077153530289291 +Threonine type peptidase activity 4 9 2.2261476844843715 0.0260042908218069 3.8106796116504857 8.762135922330097 1.392634148189787 0.2146040118876429 1.6274593113109357 0.6695334565847216 1.0340073360925757 0.2572219198248905 1.0 1.0 0.0077184558590264 1.3414362359281e-05 2.6394989589163704e-05 +Glutamate receptor binding 1 5 2.221582705293909 0.0263115197319143 2.2936893203883497 7.946601941747573 0.3900848348942944 0.57584767506371 1.7330759961215054 1.3318587299338784 0.7276949643591468 0.2861931388127574 0.0986950754944635 0.1093006244161378 0.2070995190727305 0.1139407547181512 0.3236023857744681 +Cargo receptor activity 3 7 2.2199496772243106 0.0264221837921541 3.7063106796116503 7.95873786407767 0.9623237890522576 0.1578680760704802 1.9530058934839476 1.7914972745396005 1.6202205206532496 0.203966946010782 1.0 1.0 0.0293903981750984 0.1467432355955838 0.0437795554968675 +Organic cation transmembrane transporter activity 2 7 2.20826502205889 0.0272258041003263 1.9271844660194175 5.04126213592233 1.6158747778246996 0.14183106997637 1.275055237696066 0.9168044752551467 0.8418646651592007 0.1871331589544055 0.0016026276778269 0.001984476440523 0.0002902447274798 0.0041946485896371 0.0036404640413724 +Dicarboxylic acid transmembrane transporter activity 2 8 2.198369299082352 0.027922799659948 2.842233009708738 7.20873786407767 1.0708946030323223 0.2426579907451208 1.9772646753006824 0.7975212565102757 1.0844681659651012 0.2564515003952125 0.0669039716584752 0.0742352733278267 0.1432798584585485 0.0062267265321947 0.0391317335840731 +Organic anion transmembrane transporter activity 7 35 2.159718130709868 0.0307944967596269 12.951456310679612 30.182038834951456 1.56101282472555 0.2452312368187786 6.880574373146614 3.5222410835885483 1.575669523214114 0.314839840161206 0.3086646498320265 0.3371313972628795 0.0483217377147592 0.0010205325993841 0.0075810649520667 +Macromolecule transmembrane transporter activity 3 13 2.139526566920233 0.0323930466766224 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 0.0032915927643824 0.0040679264544396 0.0008717411361388 0.01180448121602 0.0021733610219195 +Amino acid transmembrane transporter activity 3 10 2.129631112373405 0.0332020803503847 4.325242718446602 10.521844660194176 0.9562493229862624 0.2921494362491497 2.574340086864074 1.34633933573134 1.106576767449958 0.2884960270895668 1.0 1.0 1.0 0.0155108289838298 0.1254299298894934 +Sphingolipid binding 4 8 2.1269624246172767 0.0334232053787688 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 1.0 1.0 0.1596960736798767 0.0693365470158766 0.0013010595926517 +Molecular transducer activity 12 32 2.098458370533136 0.0358646736420602 10.91747572815534 33.40533980582524 1.343848990749489 0.2329582295822712 4.7124072380860955 5.830391636254363 1.6098335072319665 0.2956883791113679 0.6770062046169474 0.7160221244847005 0.453147445932042 0.5984088454862694 0.4771624278897896 +Ww domain binding 1 5 2.0964915805895497 0.0360386060182611 1.616504854368932 4.718446601941747 -0.4205734474272801 0.4557288584087624 1.1547787656296988 0.9845158065578428 1.0363685945374803 0.3093115248324538 1.0 1.0 1.0 0.0561137872346343 0.1789941624672536 +Ubiquitin like protein conjugating enzyme binding 1 8 2.0919082455262807 0.0364467243514738 3.1480582524271843 11.157766990291265 -0.1602789228193903 0.5367305081321924 1.84072619600132 1.5222820325035618 0.8886298239282414 0.2916968212143519 1.0 0.1093006244161378 0.0219975904219434 0.1139407547181512 0.1068437246174296 +Cyclic nucleotide binding 1 5 2.091833668635407 0.0364533974031837 1.2936893203883495 4.837378640776699 0.2279110104873585 0.4199844995335206 1.0742615348348612 0.5399217152263 1.1440679072094575 0.3006211359738628 0.0669039716584752 0.0742352733278267 0.1432798584585485 0.0561137872346343 0.1789941624672536 +Ceramide binding 3 6 2.06283732685636 0.0391280863059357 2.8228155339805827 5.048543689320389 1.42330045764979 0.1242195400491618 1.17628831869178 0.9309003969609838 1.481980135982154 0.2133994029014766 1.0 1.0 0.1180585699575878 0.0382400085743442 0.002702316606903 +Gated channel activity 5 14 2.021208253021324 0.0432582117379354 4.317961165048544 13.019417475728156 0.8697524591818097 0.2583579989367679 2.2914716766946497 2.0107989163575497 1.3733766112751231 0.2762671399351702 1.0 1.0 0.4407605172427877 0.1774767594454888 0.0682605802106512 +Phosphate ion binding 1 5 2.0040322950596874 0.0450666010656843 1.172330097087379 4.519417475728155 0.3003279513869437 0.5473773714904088 1.158301152955839 0.9015152565280586 0.7962961066418001 0.2795586989019824 1.0 1.0 1.0 0.0113265963942617 0.0415253310696985 +Alcohol binding 5 14 2.001094502960795 0.0453822066356954 5.70873786407767 16.094660194174757 1.0972550148478282 0.1642412137618775 2.3364194162363723 2.1334758164294443 1.72577974721897 0.2306417307890987 0.1948770046406188 0.2145132052152406 0.3837329617110586 0.342530892924546 0.0322180164961859 +L amino acid transmembrane transporter activity 2 8 1.9855466023665955 0.0470836906194473 3.628640776699029 8.201456310679612 0.919975936290114 0.2876791162304417 2.2759730869054327 1.0290432051153906 1.15482978403653 0.2925518180165951 1.0 1.0 1.0 0.0322769586697076 0.1624267369126913 +Scaffold protein binding 5 16 1.979265046271975 0.0477861728123991 4.453883495145631 19.78640776699029 0.4014949507499379 0.5241128000695782 2.407574912084857 2.8237910393168404 0.8563473729948742 0.2942678929205971 0.1771950337940978 0.1952735388158895 0.0693457394610891 0.0230341265569123 0.0201756535557514 +Mannose binding 2 6 1.9753420037553764 0.0482293495657184 2.487864077669903 6.235436893203883 0.6101269701833572 0.2582145467051042 1.3337836904766196 0.6757998162537485 1.36750331402198 0.2531492078603038 1.0 1.0 1.0 0.1781979724676324 0.005213052276273 +Peptide binding 14 67 1.972937666216752 0.0485026645706043 17.133495145631066 70.30339805825243 1.21997288878307 0.3503559587509399 5.621054768990946 6.443005397350486 1.219878183292811 0.3773673755377006 0.1321587620924428 0.1570363283812061 0.0135319942444888 0.0002322654146421 0.0007074975322617 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ab4b72a8d4185497cb035355217ac220dcd3bcc7 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 1362, + "title": "Average number of proteins per term", + "value": 16.06461086637298 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..aadd1505c2899c1c9c15189810067f12ed924b50 --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7e7a6248f0c3c6314bb07e22841f00e8f63f85db --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,382 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.9757360077644788 3.885325579591973 0.0001021928410975 0.1299405723294333 0.001855821994332 2 P30519 1 +Pattern recognition receptor activity 0.972177288903268 3.869790141856138 0.0001089290770355 0.1378874806466246 0.0019521237226629 2 Q5KU26 1 +L ornithine transmembrane transporter activity 0.9653833710773216 3.840046132751881 0.0001230111926677 0.1542669813574685 0.0021207752457406 2 P30825 1 +Transporter activity 0.4783602981300592 3.7756941701985496 0.0001595626704988 0.1953450262610006 0.0025560242840351 190 Q9BZF3,Q9HD20,Q9P0J0,Q8TDW0,Q8IXU6,O60830,Q70HW3,Q9NS69,P21796,P0CG08,Q99595,O15118,Q6P4A7,O43772,Q9HC07,P03886,P04114,O96000,Q9Y5K8,P51991,Q8NHS3,O95182,P41440,O15173,Q9Y487,P45880,O43681,P23634,P13073,Q9Y6M7,Q9C0H2,Q4KMQ2,P00846,O95563,Q9Y5P4,P51970,Q9Y584,Q99808,Q99567,Q8WTV0,P38435,P08183,Q86VD7,P30825,Q15758,Q13423,Q7KZN9,Q03518,Q9Y619,P51790,Q96H78,Q9BQT8,Q93050 53 +Er retention sequence binding 0.9456486573924304 3.7530022648673502 0.0001747292757745 0.2117989382573929 0.0027043326546016 2 O43731 1 +Nitric oxide synthase binding 0.9362665803946946 3.711278980748607 0.0002062146771015 0.2448911390014237 0.0030200472065844 2 P23634 1 +Carnitine o acyltransferase activity 0.9252669039145954 3.6620764830298937 0.0002501791379947 0.2887893474208864 0.0034074398594884 2 P23786 1 +O palmitoyltransferase activity 0.9252669039145954 3.6620764830298937 0.0002501791379947 0.2887893474208864 0.0034074398594884 2 P23786 1 +Inositol phosphate phosphatase activity 0.9210611452604376 3.643181416023344 0.0002692888993964 0.3070662433353555 0.0034506445776326 2 Q9UNW1 1 +Lysophosphatidic acid binding 0.910061468780332 3.593545651328808 0.0003262084637918 0.3587708579180054 0.0035982744032393 2 O14773 1 +Low density lipoprotein particle binding 0.958685005733528 3.5235274763931432 0.0004258429414512 0.4401697215427381 0.0043608878665905 3 Q5KU26 1 +Cytoskeleton nuclear membrane anchor activity 0.8521514073115484 3.3268568541931467 0.0008783147952824 0.6978375243714634 0.0071632619830819 2 Q8WXH0 1 +Abc type xenobiotic transporter activity 0.8456810093820851 3.2964796549514763 0.0009790470539186 0.7366088988706289 0.007752686554867 2 P08183 1 +Efflux transmembrane transporter activity 0.8456810093820851 3.2964796549514763 0.0009790470539186 0.7366088988706289 0.007752686554867 2 P08183 1 +Acid phosphatase activity 0.9316475637904926 3.142613418409431 0.0016744682721154 0.8979749939680679 0.0114901721051784 4 Q9NPH0 1 +Peptidase activity 0.488994632412461 3.1058691598854287 0.0018972064207205 0.924713123015637 0.012752272412895 105 P42785,P49721,Q5JRX3,Q4J6C6,Q9NZ08,P55786,P42892,P02786,Q96K76,Q7Z2K6,P17655,Q99436,P48147,Q96TA2,Q5TDH0,P28070,O14773,P28074,Q9H3G5,P28072,O43464,Q9UIQ6,P20618,P52888,O75976,Q9BYT8,Q92643,Q9HB40,P09960,Q9BT78,Q10713,Q9NUQ7,O43847 33 +Ion transmembrane transporter activity 0.4661447975996818 3.0514631082961885 0.0022772903142727 0.9551847358460348 0.0144056689954472 114 Q9HD20,Q8TDW0,Q70HW3,P21796,P0CG08,Q6P4A7,O43772,Q9HC07,Q9Y5K8,P41440,Q9Y487,P45880,O43681,P23634,P13073,Q9Y6M7,Q9C0H2,Q4KMQ2,P00846,O95563,Q99808,Q86VD7,P30825,Q15758,Q13423,Q7KZN9,Q9Y619,P51790,Q9BQT8,Q93050 30 +Manganese ion transmembrane transporter activity 0.836361751712603 2.98056152250882 0.0028772043742391 0.9802460285220076 0.0171104668264596 3 Q9HD20 1 +Tropomyosin binding 0.7719184729860902 2.9414435221679227 0.0032668640948898 0.9884000288745036 0.0187741303681011 2 P28289 1 +G protein alpha subunit binding 0.8828250365904388 2.932839669379846 0.0033587729311166 0.989769159903748 0.0191407896743969 4 P80303 1 +Endopeptidase activity 0.5362469652481816 2.908200171209114 0.0036351557272771 0.9929877940821802 0.0202913200842272 56 P49721,Q5JRX3,Q4J6C6,Q9NZ08,P42892,Q96K76,P17655,Q99436,P48147,Q96TA2,Q5TDH0,P28070,O14773,P28074,P28072,O43464,P20618,P52888,Q9BYT8,Q92643,Q10713,O43847 22 +Phosphatidyl phospholipase b activity 0.8162567205174354 2.8875657639612915 0.0038823543741262 0.994998701969271 0.0206553385060933 3 Q8NCC3 1 +Cardiolipin binding 0.7580071174377284 2.87261416778575 0.0040709095793207 0.9961353930980508 0.0213253032578264 2 Q9UJZ1 1 +Phosphatidylglycerol binding 0.7580071174377284 2.87261416778575 0.0040709095793207 0.9961353930980508 0.0213253032578264 2 Q9UJZ1 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.8111047301008228 2.863555178448017 0.0041891584349664 0.996712468079094 0.0217772282000929 3 Q16850 1 +L serine transmembrane transporter activity 0.7499191200258931 2.832313977693419 0.0046212446534659 0.9981796446485416 0.0232653550364892 2 Q15758 1 +Anion transmembrane transporter activity 0.5420209612919045 2.831767012652934 0.0046291565454394 0.9981992456499496 0.0232653550364892 53 Q9C0H2,Q8TDW0,P30825,Q15758,Q4KMQ2,P41440,O95563,Q9Y619,P51790,P21796,P0CG08,P45880,Q99808,O43681,Q9BQT8,Q9Y6M7,Q86VD7 17 +Vascular endothelial growth factor receptor binding 0.7476544807505736 2.8209922925907316 0.0047875353111892 0.9985501308220164 0.0237978945030648 2 Q9H2J4 1 +Sulfotransferase activity 0.7460368812682109 2.8128952523753266 0.0049097641911171 0.998773473144813 0.0242286189431213 2 Q8NCH0 1 +Protein lipid complex binding 0.8544754166538222 2.808394184239269 0.0049789241880615 0.9988842548104032 0.0244812084625987 4 Q5KU26 1 +Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor 0.7447428016823096 2.806411535968927 0.005009666597163 0.9989302326602184 0.0244996233773117 2 Q8IXB1 1 +Sodium channel regulator activity 0.8530285077505642 2.8019894437790738 0.0050788535467576 0.9990269007362382 0.0247049947524424 4 Q96PU5 1 +Ion gated channel activity 0.7837002561329347 2.734581557773683 0.006245962001993 0.9998032700521642 0.0291335624887482 3 Q9C0H2 1 +Intracellular calcium activated chloride channel activity 0.7837002561329347 2.734581557773683 0.006245962001993 0.9998032700521642 0.0291335624887482 3 Q9C0H2 1 +Procollagen proline dioxygenase activity 0.7732561736644388 2.684864377398382 0.007255924282056 0.9999507497858016 0.0327237379872857 3 Q32P28 1 +Peptidyl proline dioxygenase activity 0.7732561736644388 2.684864377398382 0.007255924282056 0.9999507497858016 0.0327237379872857 3 Q32P28 1 +Calcium activated cation channel activity 0.7169200905855782 2.6656900931610763 0.0076830481749956 0.9999725931510286 0.0338929272757781 2 Q4KMQ2 1 +Sphingolipid transporter activity 0.7691966161659747 2.665454503826094 0.0076884334102977 0.9999727949819074 0.0338929272757781 3 P08183 1 +Serine type carboxypeptidase activity 0.868327104051719 2.6644057384428166 0.0077124477605206 0.999973677078936 0.0338929272757781 5 P42785,O75976,Q9HB40 3 +Modified amino acid transmembrane transporter activity 0.8220162057866203 2.6634469981352917 0.007734459529769 0.9999744604890608 0.0338929272757781 4 P41440 1 +Tetrapyrrole binding 0.7243164455013109 2.6456273540784796 0.0081539587061414 0.9999856421980992 0.0352561643103639 18 Q8WUJ1,Q7KZN9,P09601,P30519,Q16850 5 +Xenobiotic transmembrane transporter activity 0.8159253388887114 2.6359497260233775 0.0083902161364333 0.999989620560866 0.0355996086536516 4 P41440 1 +Long chain fatty acid binding 0.7088320931737306 2.6243033218758125 0.008682642263921 0.999993054366041 0.0362753336302467 2 Q13277 1 +Class i dna apurinic or apyrimidinic site endonuclease activity 0.7072144936913709 2.6159997683944898 0.0088966617933583 0.999994823993575 0.0370558206805935 2 P23396 1 +Serine transmembrane transporter activity 0.7501618122977244 2.5738028937074633 0.0100587559012617 0.9999989528032308 0.0395954495304001 3 Q96NB2,Q15758 2 +Scavenger receptor activity 0.7985205302148439 2.55684863866682 0.0105625166549683 0.999999476466034 0.0411032790973338 4 Q5KU26,Q8WTV0 2 +Cation transmembrane transporter activity 0.4776611086379703 2.5507599315217107 0.0107488337548808 0.9999995949117798 0.0415906578811016 79 Q9HD20,P30825,Q15758,Q13423,Q7KZN9,P00846,Q70HW3,Q9Y619,P51790,Q9Y487,O43772,Q9HC07,P23634,Q93050,Q9Y6M7,Q86VD7 16 +14 3 3 protein binding 0.6942736978324167 2.5492550565141343 0.0107953315632247 0.9999996200326868 0.041652242462074 2 P85037 1 +Polypeptide n acetylgalactosaminyltransferase activity 0.6939501779359429 2.5475792076169967 0.0108473225031371 0.9999996462823796 0.0417346136985106 2 Q86SF2 1 +Palmitoyltransferase activity 0.8849520453954199 2.53948322394335 0.0111016369387582 0.999999750794173 0.0421898976282847 6 P23786 1 +Nitrite reductase activity 0.7429680403108823 2.53888810553209 0.0111205383616403 0.9999997571980292 0.0421898976282847 3 Q5VT66 1 +Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor 0.7429680403108823 2.53888810553209 0.0111205383616403 0.9999997571980292 0.0421898976282847 3 Q5VT66 1 +Structural constituent of postsynapse 0.741234141929919 2.530449792792381 0.0113916387138104 0.9999998328646444 0.0429789804105535 3 P07196 1 +G quadruplex rna binding 0.6903914590747348 2.5291214961326016 0.0114348436189775 0.9999998425229792 0.0430228094172579 2 Q06787 1 +Anaphase promoting complex binding 0.7375404530744251 2.512444113776468 0.011989809398089 0.9999999267074988 0.0446051514523906 3 Q16763,P53350 2 +Organic acid transmembrane transporter activity 0.6398455305868973 2.5109488650661933 0.0120407136954634 0.9999999316744708 0.0446051514523906 23 P30825,P41440,O95563,Q9Y619,Q96H78,Q9BQT8,P08183 7 +Pyrimidine nucleotide sugar transmembrane transporter activity 0.686832740213529 2.510620862146357 0.0120519058256092 0.9999999327206114 0.0446051514523906 2 Q9Y2D2 1 +Nucleotide sugar transmembrane transporter activity 0.686832740213529 2.510620862146357 0.0120519058256092 0.9999999327206114 0.0446051514523906 2 Q9Y2D2 1 +Serine hydrolase activity 0.6565129454000648 2.50189377924099 0.012353098138893 0.9999999555856596 0.0452282786698181 21 P42785,Q9HB40,O43464,Q5JRX3,Q4J6C6,O75976,Q6PIU2,O14773,Q9H3G5 9 +Exopeptidase activity 0.6103119074784307 2.500764579299774 0.0123925527032116 0.9999999579376908 0.0452510905677592 30 Q7Z2K6,P42785,Q9HB40,Q9UIQ6,Q9NZ08,P55786,O75976,O14773 8 +Monooxygenase activity 0.8461862474631022 2.4767586369493184 0.0132581526633546 0.9999999872581992 0.0473445438697723 8 P09601,P30519,Q16850 3 +Volume sensitive anion channel activity 0.7787011730520345 2.46581461823669 0.0136702063657947 0.999999992786088 0.048360574208344 4 Q9C0H2,P51790 2 +Protein transporter activity 0.7282560881848433 2.4503960968706235 0.0142699140657203 0.999999996849261 0.0498349306602847 15 O60830,Q9HD20,Q9Y584,Q99595 4 +Dopamine receptor binding 0.7186950038026588 2.41994560793249 0.0155228287851141 0.9999999994426922 0.0535242855831024 3 P50570 1 +Retromer complex binding 0.7676178147604125 2.4144574480934975 0.0157586635487596 0.9999999995978572 0.0542002519025521 4 P11717 1 +Copper ion transmembrane transporter activity 0.6677450663215848 2.4106538106802744 0.0159239553364973 0.9999999996800848 0.0546307989126182 2 P35670 1 +Palmitoyl protein hydrolase activity 0.8075745370147015 2.399237198024822 0.0164292683223754 0.9999999998410638 0.0558844309591592 5 Q9UMR5 1 +Proline rich region binding 0.8416691425502689 2.357291078108311 0.0184088107483491 0.9999999999897776 0.0611531713152475 6 Q9UQB8 1 +Glycosphingolipid binding 0.7548572490916106 2.354927109977997 0.0185263393324293 0.999999999991316 0.0613938544300942 4 Q9UM22 1 +Proteasome binding 0.8048383519815562 2.347369202125309 0.0189065100049214 0.9999999999948768 0.0623502823891115 9 O95456,P46379 2 +Insulin like growth factor receptor binding 0.6996763754045313 2.3255184185773143 0.0200442562095608 0.9999999999989452 0.065058197745397 3 P46108,Q04917 2 +Metallopeptidase activity 0.551318965308964 2.3251287362144843 0.0200650774940955 0.9999999999989752 0.065058197745397 37 Q7Z2K6,Q5JRX3,Q9UIQ6,P09960,P52888,Q9NZ08,P55786,O75976,Q9BYT8,Q10713,P42892,P02786,O43847 13 +Serine type exopeptidase activity 0.8220123078267901 2.320060876488238 0.0203375843833566 0.9999999999992985 0.065058197745397 7 O14773,P42785,O75976,Q9HB40 4 +Threonine type endopeptidase activity 0.8106020977570756 2.319902151640954 0.0203461711625909 0.9999999999993068 0.065058197745397 8 P28070,P49721,P28074,Q99436 4 +Phospholipase binding 0.7404725970615997 2.287303131562147 0.0221781358376089 0.9999999999999458 0.0700849675425137 4 P07196 1 +Metalloendopeptidase activity 0.7086153366548956 2.284888268652788 0.0223193800927161 0.9999999999999556 0.0703680455700912 14 Q5JRX3,Q96TA2,P52888,Q10713,Q9BYT8,P42892,O43847 7 +Snap receptor activity 0.6959460478539585 2.2784760405550126 0.0226982304200911 0.9999999999999738 0.0711829309322614 15 O75396,Q12981,Q13277,O60499,Q9P2W9,O15400,Q13190,O14653 8 +Galactoside binding 0.6402458751213234 2.2644346690509085 0.0235473936769869 0.999999999999992 0.0730008869511452 2 P16278 1 +G protein coupled serotonin receptor binding 0.6399223552248502 2.2626989262762724 0.0236542550648615 0.9999999999999932 0.073054638091477 2 P63096 1 +Oxidoreductase activity acting on nad p h heme protein as acceptor 0.734765445298512 2.2603210651976697 0.023801331518211 0.9999999999999944 0.0733425645425417 4 Q7KZN9 1 +Inorganic anion transmembrane transporter activity 0.5996902504423679 2.253633070239782 0.024219261092617 0.9999999999999968 0.0742942198381631 23 Q9C0H2,Q8TDW0,Q4KMQ2,P51790,P21796,P0CG08,P45880,O43681,Q9Y6M7 9 +Protein transmembrane transporter activity 0.7345907476666027 2.2340645231447605 0.0254788278879845 0.9999999999999994 0.0770432771020425 12 O60830,Q99595,Q9Y584 3 +Ribosomal protein s6 kinase activity 0.6334519572953776 2.2279082188406405 0.0258866360041436 0.9999999999999996 0.0775213719470595 2 P51812 1 +Threonine type peptidase activity 0.7782603667685603 2.2261476844843715 0.0260042908218069 0.9999999999999998 0.0775213719470595 9 P28070,P49721,P28074,Q99436 4 +Glutamate receptor binding 0.7679536222749065 2.221582705293909 0.0263115197319143 0.9999999999999998 0.0782451743992737 5 P41440 1 +Cargo receptor activity 0.7991834201617599 2.2199496772243106 0.0264221837921541 1.0 0.0784030813178952 7 Q5KU26,Q14108,Q8WTV0 3 +Histone h3 methyl lysine 4 demethylase activity 0.6772325112315274 2.21268365344648 0.0269194631506837 1.0 0.0791885719465037 3 Q9H6W3 1 +Organic cation transmembrane transporter activity 0.7965361222357261 2.20826502205889 0.0272258041003263 1.0 0.0795741312975204 7 Q70HW3,O43772 2 +Dicarboxylic acid transmembrane transporter activity 0.7834783478255094 2.198369299082352 0.027922799659948 1.0 0.0812980895380303 8 P41440,Q9BQT8 2 +Peptide transmembrane transporter activity 0.6741212552660756 2.1969222406157445 0.0280260001547709 1.0 0.0812980895380303 3 Q03518 1 +Map kinase scaffold activity 0.6260109996764847 2.1877203841882658 0.0286899763086498 1.0 0.0829633709817009 2 O60271 1 +Organic anion transmembrane transporter activity 0.5396929061321332 2.159718130709868 0.0307944967596269 1.0 0.0873898638993459 35 P30825,P41440,O95563,Q9Y619,Q9BQT8,Q9Y6M7,Q86VD7 7 +Tap binding 0.7136351724599637 2.1596704553947297 0.0307981899204743 1.0 0.0873898638993459 4 Q03518,P10321 2 +Glucocorticoid receptor binding 0.6205111614364331 2.157893754632499 0.0309360931852382 1.0 0.0875986671898014 2 Q04917 1 +Rna strand annealing activity 0.7114555200811795 2.149220819631366 0.0316168996619068 1.0 0.0891557294814019 4 P51114,P23588 2 +Macromolecule transmembrane transporter activity 0.6986597337498376 2.1395265669202335 0.0323930466766224 1.0 0.0905941059005334 13 O60830,Q99595,Q9Y584 3 +Amino acid transmembrane transporter activity 0.7459842319840301 2.129631112373405 0.0332020803503847 1.0 0.0915158226340882 10 P30825,Q9Y619,Q96H78 3 +Sphingolipid binding 0.7677162953538647 2.1269624246172767 0.0334232053787688 1.0 0.0915943777180748 8 P07948,Q9Y5P4,P21796,Q9UM22 4 +Molecular transducer activity 0.5448140810260498 2.0984583705331357 0.0358646736420602 1.0 0.0957239367999724 32 Q15758,Q08722,Q99720,O15173,P20645,P11717,O15118,Q15375,Q14108,Q8WTV0,Q5KU26,Q9UBG0 12 +Ww domain binding 0.7405448358229632 2.0964915805895497 0.0360386060182611 1.0 0.0957239367999724 5 Q9Y4G8 1 +Ubiquitin like protein conjugating enzyme binding 0.7600244007216527 2.0919082455262807 0.0364467243514738 1.0 0.0962200140758455 8 O14776 1 +Cyclic nucleotide binding 0.7395317305416608 2.091833668635407 0.0364533974031837 1.0 0.0962200140758455 5 P41440 1 +Galactosyltransferase activity 0.6512779714927255 2.080309631931184 0.0374971419064653 1.0 0.0984029041938455 3 O43505 1 +Ceramide binding 0.7736583968187145 2.06283732685636 0.0391280863059357 1.0 0.1017031556272605 6 Q9UM22,Q9Y5P4,P21796 3 +Gated channel activity 0.659122146482575 2.0212082530213236 0.0432582117379354 1.0 0.1089051467413457 14 Q9C0H2,P51790,P21796,P0CG08,P45880 5 +Phosphate ion binding 0.7205320078100397 2.0040322950596874 0.0450666010656843 1.0 0.1128321886975406 5 Q8NCH0 1 +Alcohol binding 0.6554034714558253 2.001094502960795 0.0453822066356954 1.0 0.1134138815372793 14 Q9BZF3,P21796,O15118,Q14108,O60762 5 +Intramembrane lipid transporter activity 0.633888794922235 1.9904982403731504 0.046536077637187 1.0 0.115240250439725 3 P08183 1 +L amino acid transmembrane transporter activity 0.7368641471571764 1.9855466023665953 0.0470836906194473 1.0 0.1157544884904103 8 P30825,Q9Y619 2 +Scaffold protein binding 0.630571666414213 1.979265046271975 0.0477861728123991 1.0 0.1170589341195821 16 P07948,P08670,P12956,Q9UQB8,P23634 5 +Mannose binding 0.7538792542862436 1.9753420037553764 0.0482293495657184 1.0 0.1175105082442013 6 O75503,P11717 2 +Peptide binding 0.4305343878948077 1.972937666216752 0.0485026645706043 1.0 0.1179654091877913 67 P24390,Q9UIQ6,Q15392,Q9Y584,Q9NZ08,P55786,Q9BYT8,Q8WTV0,O14773,P42892,O60925,Q9NQX7,O43731,Q9NXR7 14 +Sh3 domain binding 0.637494827502569 1.9589415522859064 0.0501196320552179 1.0 0.1208949867033341 15 P07948,Q16204,P50570,O75525,P46108,Q9Y5K6,P62993,Q07666,Q96D71,Q8IZP0,Q96PU8 11 +Lysophospholipase activity 0.7408055439306538 1.9586737711448767 0.0501510040289161 1.0 0.1208949867033341 7 Q8NCC3 1 +Neutral amino acid transmembrane transporter activity 0.6685521965295032 1.94100604934609 0.0522575436219197 1.0 0.1255287026685266 4 Q96NB2,Q15758 2 +Phosphatidylinositol bisphosphate phosphatase activity 0.6225901361934121 1.93166837514809 0.0534004505367358 1.0 0.1280482634349193 3 Q13614 1 +Anion channel activity 0.6584790489196785 1.9294518416714472 0.0536747931660008 1.0 0.128479909124944 13 Q9C0H2,Q8TDW0,P51790,P21796,P0CG08,P45880 6 +Lipase binding 0.6212033774615267 1.924422385960356 0.0543016606915447 1.0 0.1295251521223887 3 P04114 1 +Gtpase activating protein binding 0.7032809552469875 1.9235853585433955 0.0544065777482847 1.0 0.1295485295335031 5 Q14C86,P07437,P36405 3 +Type i transforming growth factor beta receptor binding 0.5768359754124955 1.9173779956650483 0.0551899276384846 1.0 0.1306440883948801 2 Q96AC1 1 +Transforming growth factor beta receptor binding 0.5768359754124955 1.9173779956650483 0.0551899276384846 1.0 0.1306440883948801 2 Q96AC1 1 +Mhc class ib protein binding 0.6171681535509939 1.9033065215141705 0.0570005603908145 1.0 0.1331769979104836 3 Q03518 1 +Steroid binding 0.5842423745651005 1.90159368746144 0.0572242938403613 1.0 0.1331769979104836 19 Q9BZF3,O15173,P21796,O15118,Q14108,P38435 6 +Pdz domain binding 0.6828983512649142 1.896558734234848 0.0578862012547174 1.0 0.1340833437226618 11 Q9UQB8,P51790,Q9Y4G8 3 +Oxidoreductase activity acting on other nitrogenous compounds as donors 0.6573242881415304 1.885735886268323 0.059330554440681 1.0 0.1361831932079406 4 Q5VT66 1 +Voltage gated cation channel activity 0.5687479780006549 1.8721400192658353 0.0611872346711961 1.0 0.1385037074408193 2 P06756 1 +Voltage gated calcium channel activity 0.5687479780006549 1.8721400192658353 0.0611872346711961 1.0 0.1385037074408193 2 P06756 1 +L ascorbic acid binding 0.6912494178694333 1.8670779165342728 0.061890707815114 1.0 0.1391008977626821 5 Q32P28 1 +Gtpase inhibitor activity 0.6904155130955119 1.8631493964389352 0.062441250137617 1.0 0.1398630643737751 5 O94813,Q13576 2 +L aspartate transmembrane transporter activity 0.6521907448988861 1.8603609745958565 0.0628344721337499 1.0 0.1400663683243329 4 Q15758,O75746 2 +Acidic amino acid transmembrane transporter activity 0.6521907448988861 1.8603609745958565 0.0628344721337499 1.0 0.1400663683243329 4 Q15758,O75746 2 +Sterol transporter activity 0.7147735552703829 1.8397850025760496 0.0657998081135122 1.0 0.144293835874466 7 O15118,Q9BZF3 2 +Monosaccharide binding 0.5337721157765188 1.832069958652779 0.0669409984228379 1.0 0.1461116023267713 24 Q32P28,O75503,P11717,P13674,Q5KU26 5 +Cholesterol binding 0.6529286320230739 1.8195963967847923 0.0688204908099887 1.0 0.1494952288408368 12 O15118,Q9BZF3,P21796,Q14108 4 +Heparin binding 0.6800708381504056 1.81166173186391 0.07003848006475 1.0 0.1518987417964801 10 P04114,O94813,Q53GQ0 3 +Lipid binding 0.3580273478384774 1.8019402381052156 0.0715548085617894 1.0 0.1549406188571656 128 O15254,Q9BZF3,P21796,P11717,O15118,Q9Y4G8,Q14108,P50897,P04114,Q13045,O15173,Q8NCC3,P28070,Q13432,O14773,Q9Y5P4,Q9UM22,Q06481,Q8WTV0,P38435,P53367,P07948,A6NIH7 23 +Amide transmembrane transporter activity 0.7055008005367458 1.797097234541048 0.0723201846808603 1.0 0.1561015713713657 7 Q03518,P41440,P33527 3 +Phosphatidylinositol 4 phosphate binding 0.674808111307904 1.7893419166882578 0.0735597673418226 1.0 0.158025872428332 5 P53367 1 +Hsp70 protein binding 0.6059891576034296 1.7823129829607636 0.0746982066919594 1.0 0.1597157888766857 15 P02786,P46379,Q8IXB1,P23396 4 +Protein arginine omega n asymmetric methyltransferase activity 0.5923432405419276 1.7723971974940622 0.0763286466848813 1.0 0.1626911060795124 3 Q86X55 1 +Protein kinase a regulatory subunit binding 0.6988882843240951 1.7665507786886123 0.0773034904018425 1.0 0.1634752154360844 7 Q96M27,Q9H3P7,Q9ULX6 3 +Epoxide hydrolase activity 0.6331883374200663 1.765875866179153 0.0774166769135642 1.0 0.1634752154360844 4 P07099 1 +Ether hydrolase activity 0.6331883374200663 1.765875866179153 0.0774166769135642 1.0 0.1634752154360844 4 P07099 1 +Voltage gated chloride channel activity 0.5888346431983409 1.753759918818376 0.0794716536233439 1.0 0.166267883617503 3 P51790 1 +Sterol binding 0.6100839648816029 1.7527246150300635 0.0796492884122082 1.0 0.1663839429715146 14 O15118,Q9BZF3,P21796,Q14108 4 +Polyubiquitin modification dependent protein binding 0.6676100649719487 1.7504148705645308 0.0800467518706897 1.0 0.1667028685747392 10 P46379 1 +Single stranded dna exodeoxyribonuclease activity 0.6658658945677272 1.7468187994379776 0.0806687745244989 1.0 0.1674860836926334 5 Q9UQ84 1 +Lipopolysaccharide binding 0.6913381649712282 1.7315682781306696 0.0833504583026822 1.0 0.1717132005090293 7 P28070 1 +Metalloexopeptidase activity 0.5631272867557188 1.7066396566380726 0.0878890494767481 1.0 0.1781322699216234 18 Q7Z2K6,Q9UIQ6,Q9NZ08,P55786,O75976,P02786 6 +Carboxypeptidase activity 0.6291710594708438 1.695780118372293 0.0899275290248484 1.0 0.1817229889196492 12 P42785,O75976,Q9HB40 3 +Dynactin binding 0.5770226537216867 1.6907801685513906 0.0908787961632549 1.0 0.1825618294606978 3 Q8TD16,P43034 2 +Transition metal ion transmembrane transporter activity 0.690600051929267 1.690074469192409 0.0910137085708691 1.0 0.182563580373378 6 Q9HD20,Q9HC07 2 +Voltage gated channel activity 0.6368444115912575 1.6638609922659826 0.0961402118792746 1.0 0.1897724182312639 11 P45880,P51790,P21796,P0CG08 4 +Wide pore channel activity 0.6125112034333609 1.66211017956282 0.0964906848910502 1.0 0.1899137468520383 4 P21796 1 +Porin activity 0.6125112034333609 1.66211017956282 0.0964906848910502 1.0 0.1899137468520383 4 P21796 1 +Voltage gated anion channel activity 0.6749730023091997 1.6553720019722202 0.0978490616927758 1.0 0.1923094112922954 7 P45880,P51790,P21796,P0CG08 4 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.4944784041819277 1.6295512879721696 0.1031963668019706 1.0 0.2005042105339287 28 Q32P28,P09601,P30519,P61457,Q9H6W3,Q16850,P13674,Q15800 8 +G protein beta gamma subunit complex binding 0.6405440414507759 1.6255243725438064 0.1040508749401933 1.0 0.2018764838583239 5 P63096,P04899,P41208,Q14344 4 +Peptide antigen binding 0.6733477439811443 1.6109941530876446 0.1071809968343386 1.0 0.2064788086115548 6 Q03518,Q15392,P10321 3 +Phosphatase activity 0.4330591691313691 1.5745862623921816 0.1153519758511361 1.0 0.2206592571759092 43 Q13614,Q8TF05,Q5TFE4,Q99956,Q13555,Q969T7,P49902,Q9UNW1,Q10713,Q9NPH0 10 +Signaling receptor binding 0.3418021022581602 1.555556985567252 0.1198134739255143 1.0 0.2282320999811895 155 P46379,O94813,Q9NZ08,Q9Y4G8,P04114,Q9UJZ1,Q92896,O00459,P41440,P07437,Q92520,Q9UMX5,P23634,P04899,Q96J02,Q9BRK0,P50570,O75381,Q15375,P14635,Q9NXR7,P07948,P28161,P46939,Q03518,P60520,P51572,P46108,P04439,Q9H2J4,Q96RT1 31 +Protease binding 0.4856267180217746 1.5461545416003346 0.122067249122634 1.0 0.2318766991701918 27 P41440,P46379 2 +C palmitoyltransferase activity 0.5076027175671398 1.5237254316788909 0.1275773137609563 1.0 0.2406652373163747 2 O15270 1 +Collagen binding 0.6296013769743489 1.5181434475972002 0.1289782403273531 1.0 0.2429714568822337 9 Q32P28,Q92791,Q53GQ0,O75718 4 +Phosphoric ester hydrolase activity 0.4024516685936375 1.5149713480151092 0.1297796602024081 1.0 0.2441435044139225 53 Q13614,Q8TF05,Q5TFE4,Q99956,P09601,Q13555,Q969T7,P49902,Q9UNW1,Q10713,Q9NPH0 11 +O acyltransferase activity 0.5466519502181691 1.4924683295704917 0.1355764137797619 1.0 0.2543458341157517 16 P23786,Q9HCL2,Q8NCC3 3 +Purine nucleotide transmembrane transporter activity 0.6026277795291533 1.4880513469811707 0.13673735286969 1.0 0.255848548361696 11 P41440 1 +Sulfatide binding 0.5378966068578621 1.4797935735806762 0.1389283442263136 1.0 0.2592060340222454 3 O14773 1 +Phospholipid transporter activity 0.6102762123451207 1.4789968075797648 0.1391411680383045 1.0 0.2592479765638452 5 Q9Y5P4,P08183 2 +Mrna 3 utr binding 0.4105307670749304 1.467149282455039 0.1423354502005898 1.0 0.2637563036370113 48 Q96B26,Q71RC2,Q9NZI8,P07910,Q9H2U1,P16989,Q92879,Q14011,Q15717,Q13310,Q92804,Q06787,P51114,Q08257,P22626,Q15287,Q01085,O95319,P35637,P11940 20 +Amide binding 0.3650834748548332 1.4383352170509267 0.1503389641397992 1.0 0.2748478780649751 98 P49748,P41440,P24390,Q9Y5P4,Q9UIQ6,Q9UM22,Q9Y584,Q9NZ08,P55786,O14773,Q9BYT8,Q8WTV0,Q96AY3,P42892,Q9NQX7,O43731,Q9NXR7 17 +Protein kinase a binding 0.5536187106955939 1.4358186105622526 0.1510539627091984 1.0 0.2757848488068743 14 Q9H3P7,Q9ULX6,P35241,O43823,Q96M27 5 +Cyclin dependent protein serine threonine kinase regulator activity 0.6005234696678455 1.4314765509694047 0.1522936827487653 1.0 0.2776760319997568 5 P49736,P14635,P42771 3 +Macrolide binding 0.5996225553650399 1.4270802614229987 0.1535567612628616 1.0 0.278487761438106 5 Q96AY3 1 +Fk506 binding 0.5996225553650399 1.4270802614229987 0.1535567612628616 1.0 0.278487761438106 5 Q96AY3 1 +Metalloaminopeptidase activity 0.5984887052511583 1.4051225569506312 0.1599848375868977 1.0 0.2878459032937315 10 Q9UIQ6,P55786 2 +Hormone binding 0.6270720760945522 1.3966063383823355 0.1625319832072156 1.0 0.2896276389528762 6 P42892 1 +Acyltransferase activity 0.3813777744883462 1.3895842718292264 0.1646551545154446 1.0 0.2916259043563532 56 Q9BWD1,P50416,Q8NCC3,P23786,Q9HCL2,Q86UY6,Q96G23 7 +Microtubule minus end binding 0.5902802638179653 1.3814315227554663 0.1671463191044071 1.0 0.2946827142572564 5 Q9H6D7 1 +Inorganic molecular entity transmembrane transporter activity 0.3707178155376335 1.3811055682612765 0.1672465037598085 1.0 0.2946827142572564 85 Q9HD20,Q8TDW0,P21796,P0CG08,Q9HC07,Q9Y5K8,Q9Y487,P45880,O43681,P23634,P13073,Q9Y6M7,Q9C0H2,Q4KMQ2,P00846,Q13423,Q7KZN9,P51790,Q93050 19 +Protein arginine omega n monomethyltransferase activity 0.4813976059527692 1.371503280408681 0.170218121614091 1.0 0.2972270277415428 2 O60678 1 +Mitogen activated protein kinase p38 binding 0.4813976059527647 1.371503280408654 0.1702181216140994 1.0 0.2972270277415428 2 Q15750 1 +Ribosomal large subunit binding 0.6189416630234718 1.3586611494248555 0.1742539884297045 1.0 0.3015678935721188 6 Q96E11,P98179 2 +Kinase activator activity 0.6036648024948694 1.3526648814298332 0.1761627145593087 1.0 0.3038647011314563 8 Q9NQS7,O00571,Q15750,P14635,Q8IZP0 5 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.61588532242356 1.344380402978384 0.1788254075887367 1.0 0.3075255115351761 6 Q8NBM8,Q9UHG3 2 +Oxidoreductase activity acting on a heme group of donors 0.6028829613194966 1.3146666192946808 0.188621969871122 1.0 0.3194285700887142 7 P13073,Q7KZN9 2 +Mitogen activated protein kinase binding 0.5765464022589454 1.3141495338927116 0.1887958876075 1.0 0.3194285700887142 5 Q15750,Q96JB5,Q9NUL3 3 +Lim domain binding 0.4694273697832442 1.3015726095851383 0.1930625281922537 1.0 0.3254346081656555 2 Q9Y490 1 +Protein carrier chaperone 0.5660584202792426 1.2980782589339197 0.1942604443154105 1.0 0.3270491040266863 11 P62072,O95817,Q9NPA0 3 +Nucleotide transmembrane transporter activity 0.5248773055728277 1.272200928970173 0.2033017376562869 1.0 0.3410061166106684 14 P41440 1 +Carbohydrate derivative transmembrane transporter activity 0.5243086471800962 1.268954101549834 0.2044574346818466 1.0 0.3416822405357977 14 P41440 1 +Succinate transmembrane transporter activity 0.4613393723714019 1.254225447019323 0.209760073037323 1.0 0.3488204411293669 2 Q02978 1 +Sulfate transmembrane transporter activity 0.4613393723714019 1.254225447019323 0.209760073037323 1.0 0.3488204411293669 2 Q02978 1 +Aminopeptidase activity 0.5340400012763813 1.2535396743023763 0.2100093698429375 1.0 0.3488204411293669 13 Q9UIQ6,P55786 2 +Spectrin binding 0.563779408545643 1.2514607149630772 0.2107664378680573 1.0 0.3492261415770001 5 Q13561,P35611 2 +Glycosaminoglycan binding 0.5194592430332408 1.2412558460026697 0.2145112502687443 1.0 0.3532821316396974 14 P04114,O94813,Q53GQ0 3 +Exogenous protein binding 0.4854022748515672 1.22465509198154 0.2207052010993204 1.0 0.3608649266473883 18 O15118,Q15758,Q14108,Q8WTV0 4 +G protein coupled receptor binding 0.4442517030838153 1.2054104070032925 0.2280449058976872 1.0 0.3684426593507117 24 P04899,Q9Y4G8,P50570,Q9BRK0 4 +Antiporter activity 0.5232179921917439 1.1935910708159951 0.2326379685239299 1.0 0.3745306301768233 13 P41440 1 +Vitamin transmembrane transporter activity 0.5635048064272117 1.1907288319702547 0.2337600554160777 1.0 0.375449522967804 9 P41440,P38435 2 +Secondary active transmembrane transporter activity 0.4394688921222122 1.1828523294584468 0.2368676771680116 1.0 0.3795456191798021 25 P41440,P51790,Q9Y6M7 3 +Fad binding 0.5428552432248726 1.1768928819123594 0.2392382635140189 1.0 0.3824442663217062 11 O15254,Q8NB78,Q15392,O95831 4 +Actin monomer binding 0.4818770226537266 1.173208542226135 0.2407121873115547 1.0 0.3843493541832797 3 P35080,P07737 2 +Organophosphate ester transmembrane transporter activity 0.4976268009607533 1.1567091793327604 0.2473911981070389 1.0 0.3936294530628352 15 P41440 1 +Signal sequence binding 0.4354406750817611 1.1539289959747894 0.248529280278098 1.0 0.3942552417361637 25 P24390,Q9Y584,O43731 3 +Adenylyltransferase activity 0.5439156325949526 1.1537768935567223 0.2485916496572127 1.0 0.3942552417361637 5 P51003 1 +Atpase regulator activity 0.5681815742397651 1.1488491864365944 0.250618173457092 1.0 0.3942552417361637 7 O95817,O95429 2 +Adenyl nucleotide exchange factor activity 0.5681815742397651 1.1488491864365944 0.250618173457092 1.0 0.3942552417361637 7 O95817,O95429 2 +C4 dicarboxylate transmembrane transporter activity 0.5736360167829211 1.1463822284236012 0.2516370327281119 1.0 0.3948498140272908 6 Q02978,Q9UJS0,Q15758,O75746 4 +Iron ion binding 0.4357862882096346 1.1353230115629949 0.2562400039789962 1.0 0.4006875837191652 23 P22830,Q32P28,P31350,Q9H6W3,Q16850,P13674,Q15800 7 +Nucleobase containing compound transmembrane transporter activity 0.4771445321439015 1.1234861620534544 0.2612310744049368 1.0 0.4070134904255886 17 Q9Y2D2,P51991,P41440,Q99808,O00400,Q86VD7 6 +Phosphatidylinositol phosphate phosphatase activity 0.5289513294231882 1.0801929184945167 0.2800562811714393 1.0 0.4288939639825477 5 Q13614 1 +Cyclin dependent protein kinase activity 0.5252590673575114 1.0620531450670867 0.288211559347598 1.0 0.4381073033832907 5 P11802,P50750,Q00535,P06493 4 +Vinculin binding 0.524417373699752 1.0579193530137485 0.2900922112431545 1.0 0.4404744612187029 5 P35221,P46939,P12814 3 +Lys48 specific deubiquitinase activity 0.4935926747857205 1.0521784699424488 0.2927176755089702 1.0 0.4429794156035749 4 Q93009 1 +Nucleoside triphosphatase regulator activity 0.3471035566887284 1.030059037558969 0.302982292563954 1.0 0.4564843832656032 56 Q9Y4F1,O94813,Q6IAA8,Q13576,A4D1U4,Q14344,Q14C86,Q92538,O00410,O00429,Q9Y4G8,Q9P2J5,P55010,Q66K14,P80303,Q92974 16 +Channel regulator activity 0.4814288316047184 1.0239377223669277 0.3058646913827958 1.0 0.4598098340655275 14 P05771,Q96PU5,P23634 3 +Phosphatase regulator activity 0.4676548059456497 1.0216838373842383 0.3069305632273356 1.0 0.4609034477570354 16 Q8TF05,Q86XL3,P35269,P63151,O60315,P30154,Q9NY27,P78318 8 +Adp ribose diphosphatase activity 0.4202523455192661 1.013496197331376 0.3108232115599052 1.0 0.4636815050871751 2 Q9BW91 1 +Nuclear receptor activity 0.4183112261404047 1.002157466738704 0.3162675465743731 1.0 0.4702580768933365 2 P40763 1 +Exodeoxyribonuclease activity 0.5188998436854534 1.0011466561874784 0.3167559115539751 1.0 0.4704706123626107 10 Q9UQ84 1 +Carbohydrate binding 0.3810592541461203 0.9986723609778188 0.3179534339187215 1.0 0.4717348333303908 39 Q32P28,O75503,P11717,Q9UBG0,P13674,Q5KU26,O60762 7 +Active ion transmembrane transporter activity 0.3609177044071832 0.994182513012737 0.3201340199517457 1.0 0.4744532482853946 48 Q9HD20,Q7KZN9,P41440,P51790,P23634 5 +Nucleobase containing compound kinase activity 0.4692456162694075 0.9910648972345032 0.321653892174679 1.0 0.4746706867261335 15 Q5KU26 1 +Mismatch repair complex binding 0.4485436893203933 0.9903086390288044 0.3220232852679496 1.0 0.4746706867261335 3 P43246,P12004 2 +Mutlalpha complex binding 0.4485436893203933 0.9903086390288044 0.3220232852679496 1.0 0.4746706867261335 3 P43246,P12004 2 +Passive transmembrane transporter activity 0.3861888073836459 0.9890604596948088 0.322633561764875 1.0 0.4750561201337944 37 Q9C0H2,Q8TDW0,P00846,P51790,P21796,P0CG08,P45880 7 +Non membrane spanning protein tyrosine kinase activity 0.5074140474938604 0.9745675288642328 0.3297748270669158 1.0 0.4826705789134928 5 P07948,P19525 2 +Protein tyrosine serine threonine phosphatase activity 0.5368779619526268 0.9742524443457428 0.3299312106963743 1.0 0.4826705789134928 6 Q13614,Q99956 2 +Lysine acetylated histone binding 0.513297937687702 0.9727922745454496 0.3306565530534513 1.0 0.4832126880459235 10 Q86X55,Q03164,Q15059 3 +Calcium channel regulator activity 0.4776820038287767 0.9702742350141712 0.3319098164103717 1.0 0.4845242979109607 4 P05771 1 +Lipid transporter activity 0.4351638118965321 0.9561349512459504 0.3390040586847163 1.0 0.4927679060070262 19 O15118,Q9BZF3,Q9Y5P4,P08183 4 +Membrane insertase activity 0.5207764057503835 0.9491150125337656 0.3425621198033117 1.0 0.4968792408648675 8 P62072,Q9NPA0 2 +Nadh dehydrogenase activity 0.4057176636637667 0.9408903729331324 0.3467610416088096 1.0 0.5017426862003419 25 Q9P0J0,O95182,P51970,O75380,O43678,P03886,O43676,O96000,O95831 9 +Oxidoreductase activity acting on nad p h 0.3848107926590527 0.9317746448308692 0.3514530007446164 1.0 0.5053403549340791 35 Q9P0J0,Q13423,Q7KZN9,O95182,P51970,Q9UHQ9,O75380,Q9BTZ2,O43678,P03886,O96000,O95831 12 +Lamin binding 0.5225426589942523 0.9312298186771412 0.3517346963858347 1.0 0.5053403549340791 7 O94901,Q5JTV8,Q9ULX6 3 +Cation chloride symporter activity 0.4047233904885106 0.9230209793559896 0.3559962723647376 1.0 0.5082462504829902 2 P55011 1 +Potassium chloride symporter activity 0.4047233904885106 0.9230209793559896 0.3559962723647376 1.0 0.5082462504829902 2 P55011 1 +Anion cation symporter activity 0.4047233904885106 0.9230209793559896 0.3559962723647376 1.0 0.5082462504829902 2 P55011 1 +Active transmembrane transporter activity 0.3300700606833853 0.8868902063357939 0.3751380149490615 1.0 0.5305690304887037 86 Q9HD20,Q9P0J0,O75380,P03886,O96000,Q9Y5K8,Q15388,O95182,P41440,O43676,P23634,P13073,Q9Y6M7,P51970,P00403,P08183,P33527,Q15758,Q7KZN9,P35670,Q03518,P51790,O43678 23 +Phospholipid binding 0.3295766094964809 0.8524941798461301 0.3939398679681654 1.0 0.5531403094563312 78 Q13045,Q9UJZ1,Q9Y5P4,P21796,Q8NCC3,Q9UM22,Q06481,P45880,Q9Y4G8,Q14108,Q8WTV0,P04114,O14773,P53367,P50897 15 +Protein c terminus binding 0.3512385741169508 0.8465558359242495 0.3972427392064626 1.0 0.5566302580238705 44 P12956,Q9UQB8 2 +Amyloid beta binding 0.4782902946312263 0.8411615499766906 0.4002574375911409 1.0 0.5597505344486629 11 O60925,Q9NQX7,Q8WTV0 3 +Guanyl nucleotide exchange factor activity 0.3891022507722844 0.8411007442601701 0.4002914982033756 1.0 0.5597505344486629 27 Q9Y4F1,A4D1U4,Q14C86,Q9Y4G8,P80303,Q92974 6 +Glycolipid binding 0.4780560760471309 0.8399586998064249 0.4009315434298826 1.0 0.5600705252835898 11 P07948,Q9UM22,O14773,P50897 4 +Primary active transmembrane transporter activity 0.3254450351901135 0.8319752959667039 0.4054228888439777 1.0 0.5646073359974413 62 Q9HD20,Q9P0J0,O75380,P03886,O96000,Q9Y5K8,Q15388,O95182,P13073,O43676,P23634,P51970,P00403,P08183,P33527,Q7KZN9,P35670,Q03518,O43678 19 +Phosphoprotein phosphatase activity 0.3843542949912871 0.8172505051936855 0.4137852854289654 1.0 0.5732604804498606 28 Q13614,Q8TF05,Q99956,Q9UNW1 4 +Notch binding 0.3862827563895197 0.8165917753905165 0.4141617568007802 1.0 0.5732604804498606 2 Q13573 1 +Ephrin receptor binding 0.4965125545669179 0.8086235849405422 0.4187316943968142 1.0 0.5784103121383986 7 P07948,P46108,Q15375 3 +Nadp retinol dehydrogenase activity 0.4947165867505874 0.800235593171126 0.4235743113273857 1.0 0.5823688935722257 7 Q9BTZ2,Q6UX07 2 +Structural constituent of muscle 0.4990847362275143 0.7993613201524316 0.4240809320061647 1.0 0.5823688935722257 6 P67936 1 +Rna 7 methylguanosine cap binding 0.4839434520698775 0.7973592397788928 0.4252424245400212 1.0 0.5832630233872195 9 Q96F07 1 +Growth factor binding 0.4604156537143045 0.7958051218356678 0.4261453142871645 1.0 0.5839133984498169 12 Q92896,O43847,P11717 3 +Phosphotyrosine residue binding 0.488575066834685 0.7716381490166652 0.440328772909031 1.0 0.5999913481215308 7 O00459,P46108 2 +Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides 0.4077669902912659 0.7696811307257927 0.4414890658134371 1.0 0.5999913481215308 3 P27708,Q9BPU6 2 +Oxidoreduction driven active transmembrane transporter activity 0.3689439416550704 0.7691269266721451 0.4418179646807287 1.0 0.5999913481215308 33 Q9P0J0,Q7KZN9,O95182,P51970,P00403,O75380,O43678,P03886,P13073,O43676,O95168,O96000 12 +Growth factor receptor binding 0.4460251453104606 0.7690833210901975 0.4418438488736382 1.0 0.5999913481215308 13 P07948,Q92990,Q9Y5K6,P62993,Q9NZ08,O60749,Q9H2J4 7 +2 iron 2 sulfur cluster binding 0.4761303817001183 0.7595120011340335 0.4475463377529785 1.0 0.6053208659578517 9 P21912,P0C7P0,Q6FI81,P22830 4 +Single stranded dna helicase activity 0.4532340840977371 0.7581909755481213 0.4483366629470007 1.0 0.6057882291010069 12 P25205,Q96S55 2 +Proton transmembrane transporter activity 0.3548305822680548 0.7520409317988394 0.4520264439730552 1.0 0.6095643729616844 38 Q13423,Q7KZN9,P00846,P51790,Q9Y487,Q93050 6 +Histone methyltransferase activity h3 k4 specific 0.4885083146165753 0.751149268379326 0.4525628276738678 1.0 0.6096840467772581 6 Q03164 1 +Nucleotidase activity 0.4858630748460864 0.7391586737725802 0.4598106519389042 1.0 0.6157936164609514 6 Q969T7,Q5TFE4 2 +Oxidoreductase activity 0.2783235833057902 0.7192596019577266 0.4719809819873 1.0 0.6277715795573268 238 O15254,Q9P0J0,Q9UBQ7,Q9BUP3,Q32P28,Q8NB78,P30519,P61457,Q9BTZ2,Q8N0U8,P03886,P14406,Q3SXM5,O96000,P30837,Q8N4Q0,P49748,O95182,Q9UHQ9,Q53GQ0,Q8IXB1,Q8NBX0,Q15392,P13073,O95831,P13674,Q9UHG3,P51970,P09601,Q96CU9,Q6ZRP7,Q5VT66,P48735,Q13423,Q7KZN9,O43819,Q8NBM8,Q9H6W3,Q16850,Q15800,P53004 41 +Mrna 3 utr au rich region binding 0.452769665065846 0.7113908416597655 0.4768420726484854 1.0 0.6314014553614782 11 Q96B26,Q15717,Q01085,Q9H2U1 4 +Rage receptor binding 0.3957928802589027 0.7062881026818788 0.4800089905970288 1.0 0.6347303351389838 3 Q99584,P26583 2 +Phosphatidylserine binding 0.4595267020453736 0.7047519341638757 0.4809646255289124 1.0 0.6353771289722393 10 Q14108,Q8WTV0 2 +Protein phosphatase regulator activity 0.4325085264328635 0.6966983487912535 0.485991592377657 1.0 0.6395367621433515 13 Q8TF05,Q86XL3,P63151,P30154,Q9NY27,P78318 6 +Antigen binding 0.4639517374421229 0.6785271147084412 0.4974375378334117 1.0 0.6502014649991428 8 Q03518,Q15392,P10321 3 +Gtp dependent protein binding 0.4677383890552016 0.6757930257750234 0.4991720632915002 1.0 0.6518430970307031 7 O00429,Q9BZG1 2 +Long chain acyl coa dehydrogenase activity 0.415525421859294 0.6573067409547635 0.510983702949644 1.0 0.6630281377654884 4 P49748 1 +Molecular carrier activity 0.3530915898164951 0.6341668114456741 0.5259719643754592 1.0 0.6771019049899579 32 O15504,Q9UI26,O43819,P62072,Q9NPA0,Q9P0I2,Q96P70,O95817 8 +Protein phosphatase 2a binding 0.4538213192333967 0.6317590640399539 0.5275443265938509 1.0 0.677205817927262 8 Q86XL3,P78318 2 +Modified amino acid binding 0.3677776594165067 0.6144045199987729 0.5389480496606147 1.0 0.6863668990500372 21 P41440,Q14108,Q8WTV0 3 +Metal ion transmembrane transporter activity 0.3565086309711441 0.6091239485714807 0.5424422847664174 1.0 0.6898285638205981 27 Q9HD20,Q9Y6M7,P23634 3 +Rna cap binding 0.4224722307672072 0.6003665089736826 0.548262002746225 1.0 0.6946352072003334 12 Q96F07 1 +Mhc protein binding 0.4408323993761836 0.5923518450661456 0.5536150053670466 1.0 0.7001147978736466 9 Q03518,P51572,Q9NUQ9,P07437 4 +Double stranded rna adenosine deaminase activity 0.344548689744414 0.5834875735381139 0.5595651199377334 1.0 0.7043694023615461 2 Q9NZI8 1 +Adenosine deaminase activity 0.344548689744414 0.5834875735381139 0.5595651199377334 1.0 0.7043694023615461 2 Q9NZI8 1 +Phosphatidylinositol phosphate binding 0.3509195169060183 0.5704465669527119 0.5683748532256188 1.0 0.7128237109514667 27 P53367,Q13045 2 +Abc type transporter activity 0.4235261699765318 0.5672042832558049 0.5705753983097375 1.0 0.7149252000900298 11 Q03518,Q9HD20,P08183 3 +Mhc class i protein binding 0.4365141605504266 0.5534265574652512 0.579971357758515 1.0 0.7246981552909151 8 Q03518,P07437 2 +Thiolester hydrolase activity 0.3860416173135336 0.5484135460127748 0.5834079772738767 1.0 0.7250015192034854 16 Q9UMR5,Q9NUQ7 2 +Signaling receptor regulator activity 0.3902082255884915 0.5442241887313377 0.5862872084639781 1.0 0.727915385531393 15 Q9UMX5,Q92520 2 +Dynein complex binding 0.4413135664529832 0.5427507748915047 0.5873014096669675 1.0 0.728140239482705 6 Q9UQE7 1 +Oxidoreductase activity acting on a sulfur group of donors 0.3467316583458935 0.5359696277325939 0.5919795415524873 1.0 0.732978305085898 26 Q6ZRP7,Q8NBM8,Q9UHG3,O43819 4 +Atp dependent peptidase activity 0.4133293512538719 0.5301644476259031 0.5959979183913402 1.0 0.7366144871588071 5 Q96TA2 1 +Protein arginine n methyltransferase activity 0.3884309293185447 0.5279375849466302 0.5975426570364035 1.0 0.7378541241011619 4 Q86X55 1 +Nadph binding 0.43068411195034 0.5116455350874463 0.6088991107683825 1.0 0.7471356656455288 7 Q9UBQ7,Q9NX74,Q08257,Q14739,P00374 5 +Endoribonuclease activity producing 5 phosphomonoesters 0.3880482134049647 0.5088455528194319 0.6108604866992304 1.0 0.748867671363053 14 Q9UQ84 1 +Phosphatidylcholine binding 0.4284878915847372 0.5022461793494551 0.6154943628565457 1.0 0.7524498168337984 7 P21796,Q14108 2 +Hydrolase activity acting on ether bonds 0.4304503015965168 0.4969215214985201 0.6192443942264236 1.0 0.7550679184748335 6 P07099 1 +Beta tubulin binding 0.3811034000404445 0.4958417838999951 0.6200060422704068 1.0 0.7553204200109964 15 Q9NVJ2,O75381,P60520,Q9UQE7,P50402,O75347 6 +Acetyltransferase activity 0.3350922362684385 0.475732502479896 0.6342649621992087 1.0 0.7706234420297255 29 Q9BWD1 1 +Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.3751104937554986 0.464554509454856 0.6422505154913856 1.0 0.778243062365896 15 Q9UQ84 1 +Hydrolase activity hydrolyzing n glycosyl compounds 0.4177849456626753 0.4570825951512989 0.6476116798248659 1.0 0.7833455665377153 7 P29372,O43598,P23396 3 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.3774935427645755 0.4549764271377368 0.6491261978187608 1.0 0.7844592653849706 14 Q15392,Q8N4Q0 2 +Electron transfer activity 0.2935661231119443 0.444104101342482 0.6569673213813787 1.0 0.7912484421840498 54 P48163,Q9P0J0,Q6FI81,Q7KZN9,O95182,P51970,P00403,O75380,P21912,O43678,P03886,P13073,P14406,O43676,O96000 15 +Translation initiation factor activity 0.3274268915860776 0.4386830667003774 0.6608911984143118 1.0 0.7944693841485372 31 P55010,P23588 2 +Microtubule binding 0.2907184633350396 0.4335469760375265 0.6646174463797045 1.0 0.7975409356556454 67 Q99653,Q9BXS6,P29372,Q9Y3A5,Q14203,O00429,P36405,P52732,Q13586,P23396,Q92974,Q9BRK0,Q96TC7,P50570,O75381,Q06787,Q03001,Q9BPU6,Q9H6D7,P53350,P60520,Q9BSJ2,O60313,Q96DB5 24 +Calcium ion binding 0.2928770840964383 0.4280884726044424 0.6685867089869308 1.0 0.8004219538739682 84 Q9BUP0,Q96AY3,O94813,Q9BRK5,Q14257,O60476,P67936,Q9NWM8,Q9UM22,Q9Y4G8,O95302,Q66K14,P80303 13 +Sodium ion transmembrane transporter activity 0.4107007716908775 0.4278211480146128 0.6687813388462378 1.0 0.8004219538739682 7 Q9Y6M7 1 +Poly pyrimidine tract binding 0.3858902712931382 0.4231416799441288 0.6721918941599507 1.0 0.8023885712934732 12 Q13310,P31943,Q06787,P07910,P11940 5 +Sirna binding 0.3378640776699074 0.4174192812318438 0.6763717541699656 1.0 0.8052607772548018 3 Q06787,P51608 2 +Small ribosomal subunit rrna binding 0.4098711550915745 0.4130913429388805 0.679539691837723 1.0 0.8062134671454518 6 Q14011 1 +Hydrolase activity acting on ester bonds 0.2726583468376789 0.4101357756502192 0.6817063502797562 1.0 0.8080801123420609 162 Q13614,Q9Y3B2,Q9H6V9,Q9BQP7,Q99956,Q8NHP8,Q15165,Q9UQ84,Q96B26,Q9NPH0,P50897,Q15102,Q13555,Q8NCC3,Q9UNW1,Q9UMR5,Q99575,P09601,Q969T7,Q8TF05,Q8IY17,Q10713,Q6PIU2,Q9NUQ7 24 +Symporter activity 0.3955992360270846 0.4081905533907286 0.6831337829728814 1.0 0.808365084629943 10 Q9Y6M7 1 +Structural constituent of synapse 0.383230638563485 0.4011615779980916 0.6883011667136132 1.0 0.812362382204455 5 P07196,P12814 2 +Cysteine type endopeptidase inhibitor activity involved in apoptotic process 0.3567497572029749 0.3863412513820319 0.6992439533522314 1.0 0.8238497097454491 4 P51812,Q15418,P30048 3 +Nad binding 0.3202940632871243 0.3718086307169359 0.7100353372688957 1.0 0.8306046478042799 28 P48163,Q9UBQ7,P48735,Q13423,Q16836,Q00796,Q08426,P30837 8 +Epidermal growth factor receptor binding 0.375382221051981 0.3692710616681038 0.7119256931012594 1.0 0.8315975934853477 5 P62993 1 +Translation repressor activity 0.3896809360820893 0.3551765099467403 0.7224573613368894 1.0 0.841332297165433 8 Q14011 1 +Atp dependent activity acting on dna 0.2818853991278606 0.3348525210385592 0.7377363391609304 1.0 0.8566043426574486 54 P41440,P12956,P25205,Q96S55 4 +Mirna binding 0.3546649130875545 0.3125209568002011 0.7546446388522221 1.0 0.8666323761523832 13 Q9BWF3,Q15717,P67809,Q06787,P43243,P22626,P98175,P09651 8 +Supercoiled dna binding 0.3588082901554382 0.3047710245712327 0.760540551316164 1.0 0.8711995213562788 5 P26583,P09429,O75475,P23396 4 +Calcium ion transmembrane transporter activity 0.3409334284366337 0.2967054319936318 0.7666914095669424 1.0 0.8762070202544688 15 P23634 1 +Dna helicase activity 0.2982382202671952 0.2956658264479523 0.767485297476932 1.0 0.8762070202544688 37 P12956,Q96S55,Q96RR1,P25205,P33991 5 +Cytokine receptor binding 0.3279975560995999 0.2922540946557165 0.770092354465151 1.0 0.8777119554657202 18 Q96J02,Q9NZ08,Q9NXR7 3 +Ubiquitin like modifier activating enzyme activity 0.3487694300518116 0.2677818309931343 0.788867256907015 1.0 0.8938745456799954 5 Q13564,Q9UBT2,A0AVT1,P22314 4 +Protein methyltransferase activity 0.303322091887324 0.2643612525113907 0.7915015657401432 1.0 0.8953697114103614 27 Q14166,O60725,Q15291,Q86X55,O96028,Q03164,Q15047 7 +Nadplus binding 0.3463531938545922 0.2591320413469288 0.7955333634977659 1.0 0.8985150609599118 5 Q16836 1 +Transcription coactivator binding 0.3682969149565731 0.2590438057153336 0.7956014416429176 1.0 0.8985150609599118 6 Q15648,P62829,Q00059,Q71SY5 4 +Protein kinase a catalytic subunit binding 0.3232861493284812 0.2528722879428116 0.8003669046630164 1.0 0.9016540315558548 4 P15311,P41240 2 +Demethylase activity 0.3554255192967571 0.2362940293894627 0.8132045196368312 1.0 0.910094129618212 9 Q9H6W3,Q16850 2 +Protein tyrosine kinase activity 0.3501436413726341 0.2177365551789389 0.8276343800101884 1.0 0.921699121483137 9 P07948,P11717,Q15375,P19525,P41240 5 +Oxidoreductase activity acting on the ch ch group of donors 0.2923307993925657 0.2165419991861252 0.8285652910311072 1.0 0.9219819660003008 32 P49748,Q7KZN9,Q15392,Q8N4Q0,P53004 5 +2 oxoglutarate dependent dioxygenase activity 0.3305430171159033 0.2120385498916556 0.8320769595754167 1.0 0.9236257693086533 13 Q32P28,Q9H6W3 2 +Dna n glycosylase activity 0.3319953836303027 0.2098938050989251 0.8337505573543225 1.0 0.924729852700804 5 P23396 1 +Hydrolase activity hydrolyzing o glycosyl compounds 0.3059405886613452 0.2061084078774644 0.8367062312383309 1.0 0.9270412151944945 19 O60476 1 +Cis trans isomerase activity 0.2903779400866866 0.1933137208997083 0.8467132812793539 1.0 0.936058026868896 23 O95302,Q9NWM8 2 +Dna binding bending 0.325777202072537 0.1897760462099622 0.8494846271271241 1.0 0.9380621383417972 5 O15347,Q00059,P09429,P26583 4 +Heat shock protein binding 0.2693674938485766 0.1877675274450752 0.8510588923039564 1.0 0.9385766893263064 50 P46379,P23396,Q6W2J9,Q8IXB1,Q9NUL3,Q9Y4R8,O95816,P02786 8 +Histone lysine n methyltransferase activity 0.314880232924927 0.1843035529742533 0.8537753268028501 1.0 0.9400501173043508 15 Q14166,Q03164,Q15291,O96028,Q15047 5 +Lysine n methyltransferase activity 0.314880232924927 0.1843035529742533 0.8537753268028501 1.0 0.9400501173043508 15 Q14166,Q03164,Q15291,O96028,Q15047 5 +Single stranded dna endodeoxyribonuclease activity 0.3021562765143067 0.1795988660729251 0.8574674949497678 1.0 0.9431971922320078 4 P18887 1 +Copper ion binding 0.3303841957532801 0.1736481048944148 0.8621420240508584 1.0 0.9457058522612471 11 P00403,O43819 2 +Poly a binding 0.3301443481634034 0.1728281554439488 0.862786505209509 1.0 0.9457058522612471 11 Q13310,Q71RC2,P11940,O14979 4 +Sequence specific mrna binding 0.3384116693679124 0.1724572064089834 0.8630781015864393 1.0 0.9457058522612471 8 P62495,P04818,Q06787,P00374,Q08170,P05455,P51513 7 +Hydrolase activity acting on glycosyl bonds 0.2863535957781496 0.169674306224127 0.8652662817076817 1.0 0.9465240239302158 26 P54802,P23396,O60476,P29372,O60502,Q16706,O75503,O43598 8 +Lipid transfer activity 0.3398807484741108 0.1688563381844983 0.8659096430374809 1.0 0.9465240239302158 6 Q9Y5P4 1 +Structural constituent of cytoskeleton 0.2838275755126461 0.158291683892066 0.8742269608231008 1.0 0.9522959083326024 29 Q16204,P08670,P07437,Q9UEY8,Q96RT1,P07196 6 +Pentosyltransferase activity 0.3093156537441088 0.152859495591741 0.8785090782800649 1.0 0.953365073339706 14 Q13126 1 +Tubulin binding 0.2672813909490119 0.1507529292535379 0.8801706188027558 1.0 0.953365073339706 94 Q99653,Q9BXS6,P29372,Q9Y3A5,Q14203,O00429,P36405,P50402,O75347,P52732,Q13586,P23396,P38398,Q92974,Q9NVJ2,Q9BRK0,Q96TC7,P50570,O75381,Q06787,Q03001,Q9BPU6,Q9P265,Q9H6D7,P07948,P53350,Q14166,P60520,Q9BSJ2,O60313,Q9UQE7,Q96DB5 32 +Protein tyrosine phosphatase activity 0.3184365531898659 0.1487960013695913 0.8817146059597614 1.0 0.953365073339706 12 Q13614,Q99956 2 +Aldo keto reductase nadp activity 0.3267859180243485 0.1479893361214719 0.8823511841157636 1.0 0.953365073339706 10 Q9BTZ2,Q6UX07,Q9HBH5 3 +Calmodulin binding 0.2795820130037058 0.1424714892865853 0.8867075978774208 1.0 0.9554554970799424 32 Q13576,Q13555,P49006,Q9UEY8,P23634,P35580,P35611,O43815 8 +Poly purine tract binding 0.3035093796109253 0.1319284852540137 0.8950408575754039 1.0 0.9606348684142632 14 Q13310,Q06787,Q71RC2,O14979,P11940 5 +Histone methyltransferase activity 0.2808397943863273 0.1291894861815452 0.8972077153052722 1.0 0.9622022899573076 21 Q14166,Q15291,Q86X55,O96028,Q03164,Q15047 6 +Atpase coupled transmembrane transporter activity 0.2771032056693225 0.1229930437875499 0.902112606397496 1.0 0.9636685254222664 29 Q15388,Q9HD20,Q03518,P23634,P08183,Q9Y5K8,P33527 7 +Protein disulfide isomerase activity 0.3171313620269183 0.1187423835502321 0.90547945685235 1.0 0.964375776149111 10 Q6ZRP7,P30040,Q92643 3 +Atpase binding 0.2732731390665731 0.1085577180721742 0.913553298573833 1.0 0.9720778067637192 24 Q93050,Q9Y487,P35241,P60520 4 +Protein membrane adaptor activity 0.3142719365778463 0.1032031494581827 0.9178017403551736 1.0 0.97406434895341 8 O94901,Q8WXH0,P35579 3 +Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor 0.2746924170261734 0.1028055168755756 0.9181173266348162 1.0 0.97406434895341 21 P30837 1 +Phosphatidylinositol binding 0.2603810598975656 0.1027532385134441 0.9181588189986578 1.0 0.97406434895341 46 P53367,Q13045,Q8WTV0 3 +Oxidized dna binding 0.3151797738003251 0.1024899305546732 0.9183678050150984 1.0 0.97406434895341 6 P23396 1 +Atpase coupled cation transmembrane transporter activity 0.2846527044516282 0.1016983647595065 0.9189961001506106 1.0 0.97406434895341 18 Q9HD20,P23634 2 +Smad binding 0.3081414206941332 0.0933894471397395 0.9255941738414156 1.0 0.9795332282610784 10 Q93008,Q96AC1,Q00577,Q9UNE7,P35222,Q13573,P17844,Q9UPN9,O95373 9 +3 hydroxyacyl coa dehydrogenase activity 0.3104163731299584 0.0917122475229421 0.9269266662891722 1.0 0.9801817697871524 7 Q53GQ0,Q16836 2 +Chaperone binding 0.2589797264058251 0.0884760710855229 0.9294983022493652 1.0 0.981377277258632 42 P30040,O95429,O14976,O43808,O43615,Q8IXB1,P54652,P62072,O95816,Q14108,P02786,O95817 12 +Dioxygenase activity 0.2821052224481249 0.0822738223085799 0.9344289706036988 1.0 0.984927368657739 17 Q32P28,Q9H6W3 2 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.2687055907082006 0.081517803109634 0.9350301671618624 1.0 0.984927368657739 29 Q9P0J0,O95182,Q9BTZ2,P03886,O96000 5 +Alcohol dehydrogenase nadpplus activity 0.3035020205407734 0.0781145437563287 0.9377369383006102 1.0 0.9870152318125436 9 Q9BTZ2,Q6UX07 2 +Ribosomal small subunit binding 0.3034230539716125 0.0760810744705079 0.9393545968796156 1.0 0.987954410000028 8 P61221,P23588 2 +Poly g binding 0.2800330384273298 0.0667568434333235 0.9467752806781125 1.0 0.993457574948836 5 O14979 1 +Gamma tubulin binding 0.2987090985286 0.065000652728456 0.9481734805533388 1.0 0.99415879947163 6 P07948 1 +Microtubule plus end binding 0.2955988615302551 0.0611459500905695 0.9512429747073248 1.0 0.996225603957142 10 Q03001,Q13586,Q14203 3 +Modification dependent protein binding 0.2507320528514936 0.0592719695218612 0.9527354869320428 1.0 0.9966403480809848 52 P07948,P46379,Q15059,Q9UFC0,Q15291,Q86X55,Q03164,Q9ULU4,Q9NXR7 9 +Phosphatidylinositol 3 4 5 trisphosphate binding 0.2937743190661502 0.054968110918789 0.9561638691675172 1.0 0.9994590865741814 9 Q96AC1,P46940,Q13576,O15294,Q92538,Q9H0H5,Q9BWH2,Q8N668 8 +Snare binding 0.2612105989305097 0.049461559958144 0.9605514703939352 1.0 1.0 27 Q13190,O15400,P60520,O14653 4 +N acetyltransferase activity 0.2773141155480685 0.0491101986709189 0.9608314758518968 1.0 1.0 14 Q9H9T3,Q9BXJ9,Q9UKN8,O75448,Q86UY6 5 +Nuclear export signal receptor activity 0.2896953985742077 0.0457939868143013 0.96347445161156 1.0 1.0 7 O14980,O15504,P35658,P55060,Q9HAV4,Q9UIA9 6 +Oxidoreductase activity acting on the aldehyde or oxo group of donors 0.2563162414848113 0.0407274906367184 0.9675131454141273 1.0 1.0 23 P30837 1 +Endoribonuclease activity 0.2552011434433739 0.0404275045951122 0.9677523026730196 1.0 1.0 22 Q9UQ84 1 +Regulatory rna binding 0.2720388305906682 0.0382746678564751 0.9694686881046404 1.0 1.0 15 Q9BWF3,Q15717,P67809,Q06787,P43243,P22626,P98175,P09651 8 +N acyltransferase activity 0.2672258392039211 0.0344971379235679 0.9724807245976534 1.0 1.0 17 Q9H9T3,Q9BXJ9,Q9UKN8,O75448,Q86UY6,Q96G23 6 +Phosphoprotein binding 0.253338521710396 0.0226923313301391 0.9818956929741054 1.0 1.0 25 O00459,P07948,P29372,P46108,P11717 5 +Ubiquitin like protein specific protease activity 0.2535905740083184 0.018323711786319 0.9853806113707946 1.0 1.0 27 Q9HBH5,Q9H8M7,Q9BT78,Q96K76,Q93009,Q9NUQ7,O15372,Q99496 8 +Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor 0.2490284974093242 0.0099336074814313 0.9920742583051888 1.0 1.0 5 P21953,Q02218,P08559,P11177 4 +Protein domain specific binding 0.2482078977242339 0.009549235282059 0.9923809283956632 1.0 1.0 176 Q6P1K2,P61978,Q9Y4G8,Q9NQ29,Q96K76,P41440,Q16625,P07437,Q16629,Q9UQB8,P23634,P80723,P08670,P50570,P53367,O15126,P07948,Q16204,P46108,P51790,P20645,P07196 22 +Methyl cpg binding 0.2692871567228804 0.0085930738231071 0.9931438034447816 1.0 1.0 11 Q9Y3Y2 1 +Flavin adenine dinucleotide binding 0.2508246076402981 0.0015038823790721 0.9988000759207788 1.0 1.0 31 O15254,P49748,Q8NB78,Q9UHQ9,Q15392,O95831 6 +Amp binding 0.263123784834746 0.0001818846742422 0.9998548770273756 1.0 1.0 7 P17858,Q9NUB1,P06737,P07741,P54619,Q01813 6 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ed34a52e3eb9ed8ee571936ab14fe46274be9980 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 3 kinase regulator activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5alpha androstane 3beta 17beta diol dehydrogenase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 1 adaptor complex binding", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide 1 phosphate binding", "Ceramide 1 phosphate transfer activity", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Choline transmembrane transporter activity", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromatin insulator sequence binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Copper ion transmembrane transporter activity", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix protein binding", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibronectin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyl n acetylgalactosaminyl proteoglycan 4 beta n acetylgalactosaminyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophosphodiester phosphodiesterase activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanosine diphosphatase activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Icosanoid binding", "Identical protein binding", "Igg binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n acetyltransferase activity acting on acetyl phosphate as donor", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Neuregulin binding", "Neurexin family protein binding", "Neurotransmitter binding", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphate ion transmembrane transporter activity", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphorylation dependent protein binding", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Platelet derived growth factor receptor binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein cysteine s stearoyltransferase activity", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase 2b binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein self association", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp n acetylglucosamine transmembrane transporter activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL8A", "ARL8B", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPIF1", "ATRIP", "ATRX", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf35", "C1orf52", "C2CD5", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC22", "CCDC47", "CCDC59", "CCDC6", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA5", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPV", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "COG2", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC19", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GID8", "GIGYF2", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPI", "GPR107", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS4", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1147", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LETMD1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLPH", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LZIC", "M6PR", "MACF1", "MAEA", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NES", "NFS1", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NKRF", "NKTR", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDZD8", "PEBP1", "PECR", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2B", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PWWP2A", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RTCB", "RTF1", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35A4", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPOP", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFRC", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKT", "TLE3", "TLN1", "TM7SF2", "TMBIM6", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM165", "TMEM192", "TMEM201", "TMEM43", "TMEM59", "TMEM70", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPYL1", "TST", "TTC1", "TTC26", "TTC4", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBFD1", "UBIAD1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "URB1", "UROD", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VPS16", "VPS25", "VPS33B", "VPS35", "VPS4A", "VRK1", "VRK2", "WARS", "WARS2", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZCCHC17", "ZCCHC3", "ZCCHC8", "ZDHHC20", "ZEB2", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF148", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF644", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCC1", "ABCE1", "ABI1", "ACADVL", "ACAT2", "ACBD3", "ACOX3", "ACP6", "ACSS1", "ACTN1", "ADD1", "ADD3", "AIFM1", "AKAP8", "AKAP8L", "ALDH1B1", "ANKLE2", "ANO6", "APLP2", "APOB", "APRT", "ARFIP1", "ARHGEF2", "ARL3", "ARL8B", "ASNA1", "ATP13A1", "ATP2B4", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP7B", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG6", "BAIAP2", "BASP1", "BCAP31", "BCKDHB", "BCOR", "BICD2", "BLVRA", "BNIP1", "BRCA1", "BRD3", "CAD", "CAMK2G", "CAPN2", "CARM1", "CCDC6", "CCNB1", "CD2AP", "CD47", "CDK1", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKN2A", "CELF1", "CELF2", "CERS2", "CETN2", "CHP1", "CHST14", "CHTOP", "CIAPIN1", "CIRBP", "CISD3", "CLCN3", "CLN5", "COL4A3BP", "COLEC12", "COMMD1", "COPS4", "COX15", "COX2", "COX4I1", "COX7A2", "CPD", "CPT1A", "CPT2", "CPVL", "CRK", "CRTAP", "CRYZ", "CSE1L", "CSK", "CTNNA1", "CTNNB1", "CYB5D2", "CYB5R1", "CYFIP2", "CYP51A1", "DCTN1", "DCTN2", "DDI2", "DDX3X", "DDX5", "DHCR24", "DHFR", "DHRS13", "DHRS4", "DHX36", "DIP2B", "DNAJC10", "DNM1L", "DNM2", "DNPH1", "DPM1", "DPYSL5", "DST", "DUS2", "DUSP9", "ECE1", "EFHD1", "EHHADH", "EIF2AK2", "EIF3H", "EIF4B", "EIF5", "ELAVL1", "ELP3", "EMC3", "EMC7", "EMD", "EPDR1", "EPHA7", "EPHX1", "ERAP1", "ERBIN", "ERMP1", "ERP29", "ETF1", "EXO1", "EXOSC1", "EXOSC8", "EZR", "FAM3C", "FAM49B", "FARP1", "FECH", "FERMT2", "FKBP10", "FKBP14", "FKBP9", "FLII", "FMR1", "FOXK1", "FOXRED1", "FUNDC2", "FUS", "FXR1", "GABARAPL2", "GAK", "GALNT7", "GAPVD1", "GBF1", "GGCX", "GLB1", "GLG1", "GLMN", "GNA13", "GNAI1", "GNAI2", "GOSR2", "GPAM", "GPR89B", "GRB2", "GRHPR", "GSTM2", "GTF2F1", "GTF3C4", "HADH", "HAUS4", "HLA-A", "HLA-C", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPDL", "HNRNPH1", "HNRNPK", "HSD17B12", "HSDL1", "HSPA2", "HTATIP2", "HTRA2", "ICMT", "IDH2", "IGBP1", "IGF2BP1", "IGF2R", "INCENP", "IPO11", "IPO5", "IPO7", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGAV", "ITM2C", "KDELR1", "KDELR3", "KDM1B", "KHDRBS1", "KHDRBS3", "KIAA1147", "KIF11", "KMT2A", "LAMTOR1", "LARP4", "LARS", "LBR", "LDAH", "LNPEP", "LRRC8C", "LRWD1", "LTA4H", "LUC7L", "LYN", "M6PR", "MAN1A2", "MAN2A1", "MARC1", "MARCKSL1", "MATR3", "MCM2", "MCM3", "MCM4", "ME1", "MECP2", "MED1", "MED24", "MED25", "MFSD8", "MGEA5", "MGME1", "MINDY3", "MINPP1", "MPC2", "MPG", "MRC2", "MRRF", "MSH2", "MSMO1", "MTAP", "MTMR2", "MYH10", "MYH9", "NAA15", "NAA40", "NAE1", "NAGLU", "NCEH1", "ND1", "NDUFA13", "NDUFA2", "NDUFA7", "NDUFA8", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFS6", "NEDD4L", "NEFL", "NENF", "NLN", "NNT", "NOVA1", "NPC1", "NPEPPS", "NRDC", "NSD2", "NT5C2", "NT5C3B", "NT5DC1", "NUCB2", "NUDT9", "NUP214", "NUP88", "NUPL2", "NUSAP1", "OCLN", "OGDH", "OGT", "OPA1", "OSBPL6", "P3H1", "P3H4", "P4HA1", "PABPC1", "PABPC4", "PAFAH1B1", "PAFAH1B3", "PAPOLA", "PCBD1", "PCNA", "PCYOX1", "PCYOX1L", "PDCL3", "PDHA1", "PDHB", "PEX14", "PFDN1", "PFKL", "PFKP", "PFN1", "PFN2", "PGRMC2", "PIGK", "PIK3R2", "PITRM1", "PLA2G15", "PLBD2", "PLK1", "PMF1", "PMPCA", "PNPLA6", "PON2", "POP1", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP4R2", "PPT1", "PPT2", "PRCP", 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1.8349514563106797 5.186893203883495 0.878985239421048 0.4043272377350911 1.2929764516183682 0.5365505235508999 0.7767472061372565 0.306948917766608 1.0 1.0 1.0 0.0561137872346343 0.0391317335840731 +Mitochondrial respiratory chain defects 2 6 2.2987554327913617 0.0215188308433722 1.8033980582524272 5.177184466019417 1.0048180638921334 0.285673153216041 1.1353491002390874 1.0681459460620504 1.0953831291184488 0.2879410254685434 0.0021018010008498 0.0026008925831016 0.000440337804097 0.0062267265321947 0.0061301079468053 +Distal muscle weakness 9 61 2.293557097938796 0.0218159520898801 13.99514563106796 64.27912621359224 0.378143548680081 0.6371085023737708 5.834278994576672 7.014703781301811 0.8046554605614199 0.3362876084172668 0.0280225225113226 0.0369413340125406 0.0158491381338637 0.0040287665764379 0.0335991250904749 +Abnormality of lower limb metaphyses 1 5 2.2929833419866656 0.0218489640092836 1.555825242718447 6.567961165048544 0.325931310493526 0.581716400339986 1.7121184426589482 1.378666415733149 0.7913367048445564 0.30401595093073 1.0 1.0 0.1349531130589082 0.307957256786686 0.1615113588580296 +Bulbar signs 2 11 2.261995173009696 0.0236977015288371 4.888349514563107 12.016990291262136 1.527818207801298 0.1656113111527082 2.218011046873564 1.4803576942139227 1.2783367300196684 0.2344360472575242 0.0083155770901944 0.0102371045657047 0.0034893000144238 0.0415700360883472 0.0662412432855518 +Abnormal csf protein level 2 13 2.2552971421727563 0.0241146838972585 4.434466019417476 12.20631067961165 1.1239853500963992 0.2260559983233297 2.11400242863219 2.084072511592451 1.241935948510828 0.248039542652958 0.0006148568653246 0.0008441205885139 0.0061250241039257 0.0678108138951911 0.0381699787004707 +Blurred vision 1 5 2.231859883203027 0.0256242250195517 1.4684466019417477 4.449029126213592 0.7772225957067546 0.3401357669580369 0.986055451759567 0.9450042528934012 1.0938682095756602 0.2939628040587096 0.0789520148513954 0.0875404472016038 0.014058804472369 0.0762921742488627 0.232790248880933 +Coxa vara 6 15 2.2304552529457857 0.0257172349542931 4.310679611650485 13.54126213592233 0.853738655548226 0.4218003203060939 1.9720332330132235 1.9928869528934432 0.8140335419312188 0.3116542205645756 1.0 1.0 0.327507803675052 0.002945649466309 0.0031456326440873 +Muscle stiffness 5 21 2.224176264314828 0.0261365873516503 5.109223300970874 19.216019417475728 1.2530133657268057 0.2695837776665858 2.5817154639007844 2.4582801786037667 1.0397164239726309 0.2961148999712332 0.2121874464474668 0.2333020504203794 0.0157478410048603 0.0438041643494559 0.0481684147987639 +Mitochondrial inheritance 1 5 2.2093399284770725 0.0271510059220092 1.577669902912621 4.247572815533981 0.9928856357718184 0.2727497270810077 1.119676794457053 1.2095369137272214 1.2442723588935711 0.2811589341958167 0.062853835992264 0.0697581245313758 0.0088504827764808 0.0498779046475234 0.0329439287769651 +Abnormal upper motor neuron morphology 1 9 2.207231744546729 0.0272978730602653 2.104368932038835 10.152912621359222 0.6668580581129538 0.4264480473015415 1.810508789672501 1.2708136152843803 0.93546763978058 0.305632736845798 0.0749529906412748 0.083126337411673 0.1596960736798767 0.0693365470158766 0.214697112815727 +Occipital meningocele 2 5 2.154030572984711 0.0312377743983334 1.614077669902913 5.305825242718447 0.4694090704141183 0.5064024976559787 1.173781489144657 0.9895890333349424 0.8607405237454151 0.3006870950401374 1.0 1.0 1.0 0.2365379696877526 0.0958131716431155 +Abnormal circulating acetylcarnitine concentration 1 7 2.133356625214457 0.0328954823523361 1.7475728155339805 6.606796116504855 1.2739071869107932 0.2367430781797907 1.3686393682873708 0.7076231425197869 0.8717674578101685 0.2465605045996027 0.0011687386103089 0.0014481500629001 0.0056684159955205 0.0328731354880699 0.1114297880404725 +Amyotrophic lateral sclerosis 2 13 2.1200447702759173 0.0340022698979507 4.453883495145631 16.203883495145632 1.0855969203541704 0.3037117925086244 2.3812188822255287 1.5445439412417563 1.0118111691913367 0.2917679915833991 0.162776730222371 0.1795501084992132 0.327507803675052 0.0764078368784309 0.3172421403160574 +Demyelinating peripheral neuropathy 3 15 2.11752695489805 0.0342151501252143 3.6189320388349513 16.41990291262136 0.8004175255851168 0.4261699448763591 1.908827430762096 2.446692237122478 0.9042326115295364 0.3171508979101954 0.0006148568653246 0.0008441205885139 0.000509979222831 0.0142235096743441 0.0102933346763684 +Muscle weakness 53 288 2.1089810610963324 0.0349462164097764 62.08495145631068 284.65776699029124 0.4543336947629458 0.7075817001495509 18.861530859314332 26.81339440066312 0.9176952901579704 0.374241019778978 0.0096443798223082 0.0181335235208407 0.0170895122146583 0.0001904177807049 3.750223646231316e-05 +Hypothermia 4 12 2.105695409424791 0.0352308188515806 2.4174757281553396 9.49271844660194 1.0856169578047503 0.2588610618328691 1.611694349619475 1.8201795996814751 1.0634596616937388 0.2538467530049644 0.0043471847254306 0.0053672672920639 0.0013262573806951 0.0001885722773553 0.0006117952479182 +Macrovesicular hepatic steatosis 6 7 2.101553134208233 0.0355924388899269 2.466019417475728 6.87621359223301 0.939079379807938 0.3067324443022926 1.4701927354039712 1.258646689249585 1.014263353538022 0.2700508944960845 0.0423440523288004 0.0470522829573702 0.0921025797166938 0.001485709034831 5.279662360650864e-05 +Episodic vomiting 4 14 2.0962364800167026 0.0360612183509923 4.179611650485437 11.12378640776699 1.060494846441687 0.2663322982599159 1.9809215871966128 1.7630834730718608 1.1982900451883365 0.2840581402107739 0.1256421060924307 0.1389130578490434 0.0354914601129098 0.0063239101987386 0.0154010672791248 +Astrocytosis 0 5 2.063856626641646 0.0390313121861776 1.7888349514563109 6.650485436893204 0.2566372779470236 0.4739812199291527 1.6624264643760962 1.3525146508840034 1.0110665114325208 0.308672837139904 1.0 1.0 0.1758008751515455 0.3879443652654283 0.6284576152398091 +Axonal degeneration 2 6 2.063771380423302 0.0390393978151366 1.953883495145631 6.33252427184466 0.7159471209009113 0.4369970691072399 1.334860985460392 1.282295588998971 0.8258089310760343 0.3006708246946786 1.0 1.0 1.0 0.0062267265321947 0.0391317335840731 +Abnormality of renal excretion 0 6 2.0513365230920213 0.040234186039638 0.9854368932038836 6.776699029126213 0.6442154854600826 0.4742848097497059 1.381142608933526 0.6816889196715323 0.849303919889795 0.31439981627391 0.0908479857652614 0.1006582454154426 0.191600110602388 0.4172977923286156 0.6635182138461756 +Ventricular arrhythmia 14 34 2.0381044737908103 0.0415394858554434 10.0 36.96601941747573 1.0415384316890377 0.3677574027458479 3.8522468541414527 4.8022861343455805 1.0152201826292362 0.3231502492090489 0.000908511851067 0.0013653653935254 0.0028323971587756 0.0112337149724148 0.0236019283340162 +Deep palmar crease 6 11 2.023148603693953 0.0430578287793248 3.866504854368932 11.75728155339806 0.5990239856383347 0.4998099821006278 1.9281120141985588 1.1231545330869228 0.7799394834925686 0.2989134885739745 1.0 1.0 1.0 0.1060727287920157 0.0228511399682266 +Hypoplasia of the musculature 1 5 2.0203054611213607 0.0433517126963947 1.412621359223301 5.393203883495145 0.6491558839366509 0.4339241341629252 1.0724420559765822 0.8594152602202743 0.8694942858597294 0.2925094147190523 0.062853835992264 0.0697581245313758 0.1349531130589082 0.0498779046475234 0.1615113588580296 +Rhabdomyolysis 3 15 2.014897131801165 0.0439154285985001 3.0242718446601944 13.451456310679612 0.3809613122276756 0.4596197923813932 2.630920176410559 1.2027770518432574 0.9520162845961792 0.2764012957742299 0.0073328074064037 0.0090330503435184 0.0028960612595367 0.0056128198685199 0.0543801140407061 +Abnormal speech prosody 1 8 2.0118897639962623 0.0442315586555515 1.7184466019417477 7.531553398058253 0.8238611105871386 0.3292070194756458 1.3593793253030109 1.1305443806694235 1.0768574157850217 0.2870822069632543 0.070936999678044 0.0786913117950012 0.0113213926532688 0.062605312422627 0.1967448754466316 +Pendular nystagmus 2 7 2.005757721741089 0.0448821034251465 1.635922330097087 6.162621359223301 0.2094781614976387 0.4554400721653512 1.5559066516120088 0.9554447560554616 1.0787950758907725 0.3151205808465558 1.0 1.0 0.1596960736798767 0.0693365470158766 0.0531269764991638 +Polyphagia 1 6 2.0040156674052594 0.045068382145516 2.5145631067961167 7.684466019417476 0.0300396919709153 0.5779048306307499 1.8920584037759212 1.7172600258604214 0.8405756412544837 0.2977280257161214 0.1518012535528692 0.1675604235637086 0.3076603852203092 0.2345960405017343 0.5535889295625431 +Abnormal neuron morphology 3 24 2.003304006604123 0.0451446677106519 6.186893203883495 28.24514563106796 0.6484714329574719 0.4735595458743487 3.2896606279139218 2.2567268866496706 0.9337112301481814 0.3347227917865519 0.2555101444842079 0.2801168002074996 0.4825947600252522 0.0824194625829831 0.4172172592589917 +Hyperventilation 1 6 1.991049214564296 0.046475476925569 1.5121359223300972 5.842233009708738 0.257199533402791 0.3684899252913141 1.1070595624125217 1.4234045280807717 1.1968077455675237 0.2703462773314473 0.0947798403579739 0.1049896535105009 0.0202898922491691 0.1060727287920157 0.3055391640015715 +Pain 22 167 1.9853265709146988 0.0471081496606964 37.08009708737864 174.89563106796118 0.560521494187844 0.6082034136674831 12.418311408681989 15.731400802334642 0.9626712538875356 0.3834317739449847 0.1537537642129376 0.2011557632640148 0.0926594565378828 0.0134965839788371 0.0631914387601362 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a402bf3334ae8d0d4a3a0c26e52818485b0697dd --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 4530, + "title": "Average number of proteins per term", + "value": 23.4 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2ab1f499ebad22e833411ae4d55d5a5295210184 --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7ce7eae5f45578c8cedf4d6725e79bf0b4cee006 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1304 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Retinal arterial tortuosity 0.9773536072468468 3.8923770240611018 9.926682019156809e-05 0.3621811792812978 0.0036804050710543 2 P03886 1 +Leber optic atrophy 0.9773536072468468 3.8923770240611018 9.926682019156809e-05 0.3621811792812978 0.0036804050710543 2 P03886 1 +Multiple glomerular cysts 0.9773536072468468 3.8923770240611018 9.926682019156809e-05 0.3621811792812978 0.0036804050710543 2 P03886 1 +Low plasma citrulline 0.9773536072468468 3.8923770240611018 9.926682019156809e-05 0.3621811792812978 0.0036804050710543 2 P03886 1 +Intracellular accumulation of autofluorescent lipopigment storage material 0.9340019411193792 3.701174380631096 0.0002146039242261 0.6217727622410446 0.0056894169956817 2 O14773 1 +Cold induced muscle cramps 0.978352547428112 3.6073924395801154 0.0003092896857022 0.7537231553503175 0.0073975690838524 3 P23786 1 +Episodic respiratory distress 0.9527203147744882 3.4979140047241133 0.0004689123025767 0.8805277212820709 0.009398994383507 3 P03886 1 +Vascular tortuosity 0.95141672319426 3.4923049120101033 0.0004788712615573 0.8858002744827382 0.0095563295808576 3 P03886 1 +Psoriasiform dermatitis 0.8663862827563891 3.3932687942527777 0.0006906383265015 0.95626788192197 0.0117791789299852 2 Q15800 1 +Long upper lip 0.8628275638951854 3.3767192793480083 0.0007335587483237 0.9640001512489086 0.0123206118513237 2 Q9BZK7 1 +Chorioretinal hypopigmentation 0.8615334843092917 3.37069247195202 0.0007497950793631 0.9665547569324898 0.0124416546136079 2 Q9Y619 1 +Extra axial cerebrospinal fluid accumulation 0.846328049175024 3.2995227637825035 0.0009684937246194 0.987591858759626 0.0144435054866806 2 P20700 1 +Excessive wrinkling of palmar skin 0.906871348429393 3.298161749514565 0.0009732005552485 0.987853875525577 0.0144435054866806 3 Q9BZK7 1 +Abnormality of the foot musculature 0.8375930119702428 3.258339118324167 0.0011206639914242 0.9937766976829696 0.015601459684553 2 P50570 1 +Abnormal superior cerebellar peduncle morphology 0.8291814946619276 3.218471752837922 0.0012887566373116 0.99709648360475 0.0173236426321121 2 Q10713 1 +Elongated superior cerebellar peduncle 0.8291814946619276 3.218471752837922 0.0012887566373116 0.99709648360475 0.0173236426321121 2 Q10713 1 +Scanning speech 0.8801397413124159 3.179280356995474 0.0014764121526322 0.9987605519844162 0.0187210541367438 3 Q8IY17 1 +Peripheral hypermyelination 0.8770226537216654 3.1652984552401433 0.0015492394955809 0.9991092946314624 0.0194599698157414 3 Q13614,Q9NR77 2 +Protrusio acetabuli 0.8603164527356287 3.089928496191553 0.0020020468717769 0.9998858917522746 0.0224486938840337 3 Q96AY3 1 +Alveolar ridge overgrowth 0.7861533484309355 3.0112445446993186 0.0026017922171837 0.9999925065249284 0.027032382440005 2 Q15392 1 +Abnormal urine sodium concentration 0.7855063086379904 3.0080854295723607 0.0026289922335507 0.9999933773640274 0.0271283253257057 2 Q13423 1 +Knee clonus 0.7780653510190914 2.971662331522345 0.0029619224615717 0.999998540503268 0.0296847538737172 2 Q8N0X7 1 +Chondrosarcoma 0.8316263396430006 2.958757892253043 0.0030888166873146 0.9999991800267196 0.0306178109267731 3 P48735 1 +Abnormality of the brainstem white matter 0.8294498381876975 2.9487158806407456 0.0031909718683071 0.9999994845443942 0.0311532382832577 3 Q10713,P20700 2 +Decreased palmar creases 0.7696538337107843 2.9302804098371724 0.0033865625308784 0.9999997881026564 0.0326406984359134 2 Q8NCH0 1 +Morning glory anomaly 0.7580071174377214 2.8726141677857164 0.0040709095793212 0.9999999905651812 0.0362398726675726 2 O00429 1 +Temporal optic disc pallor 0.7580071174377214 2.8726141677857164 0.0040709095793212 0.9999999905651812 0.0362398726675726 2 O00429 1 +Agenesis of cerebellar vermis 0.7576835975412592 2.871006177861188 0.0040916752832784 0.9999999914155464 0.0363437039867676 2 Q10713 1 +Atlantoaxial abnormality 0.8106744399976092 2.86154648046937 0.0042157968207616 0.999999995119064 0.0368678756719119 3 Q9NWM8 1 +Polar cataract 0.7460368812682105 2.8128952523753266 0.0049097641911171 0.9999999997925252 0.041806826664969 2 P08670 1 +Prominent crus of helix 0.7460368812681998 2.8128952523752826 0.0049097641911177 0.9999999997925252 0.041806826664969 2 Q9H5V9 1 +Lumbar kyphosis 0.742801682303468 2.7966758040998063 0.0051631312585249 0.9999999999345396 0.0434739490727102 2 Q96AX1 1 +Flattened epiphysis 0.8474825598379766 2.777391866613813 0.0054797069858041 0.9999999999845178 0.0452975778206071 4 O95831 1 +Reduced forced vital capacity 0.8452104685774193 2.7672923609580264 0.0056524039524601 0.9999999999929504 0.0459306027166861 4 Q9BQT8 1 +Hyporeflexia of upper limbs 0.7905436501953517 2.7669883961122683 0.0056576768909295 0.9999999999931176 0.0459306027166861 3 Q9NR77 1 +Centrocecal scotoma 0.8391439704496968 2.7402630054862 0.0061390037740731 0.9999999999992324 0.0487034800289868 4 P03886 1 +Breathing dysregulation 0.7822834376093792 2.727855460768053 0.0063747533793763 0.999999999999738 0.0500954911369696 3 Q10713 1 +Profound sensorineural hearing impairment 0.8334762710517485 2.71492654685013 0.0066290471654322 0.9999999999999178 0.0514205199647396 4 Q9NR77 1 +Sensorimotor neuropathy 0.635588957167469 2.705955847812323 0.0068108100613217 0.999999999999964 0.0527056379460043 31 P41440,Q9NR77,P03886,O95831,Q5KU26 5 +Segmental peripheral demyelination remyelination 0.8775906735751292 2.704081643005699 0.0068493458008735 0.99999999999997 0.0527056379460043 5 Q9NR77,P03886,P50570,P00846 4 +Molar tooth sign on mri 0.7759822292823197 2.6978716206501407 0.0069784346802947 0.9999999999999832 0.0533991707799585 3 Q10713 1 +Abnormal echocardiogram 0.8237506963674259 2.6712599849281315 0.0075567092794293 0.9999999999999988 0.0557498527416521 4 P49748 1 +Deformed sella turcica 0.7699029126213566 2.6688349390025685 0.0076114845686818 0.9999999999999992 0.0557498527416521 3 O75431,Q96AX1 2 +J shaped sella turcica 0.7699029126213566 2.6688349390025685 0.0076114845686818 0.9999999999999992 0.0557498527416521 3 O75431,Q96AX1 2 +Aplasia hypoplasia of the palmar creases 0.7699029126213458 2.66883493900251 0.0076114845686832 0.9999999999999992 0.0557498527416521 3 Q8NCH0,Q99567 2 +Action tremor 0.50456798170006 2.658821410804658 0.0078414516377256 0.9999999999999996 0.0557498527416521 57 Q96RL7,Q9BRK0,Q8IY17,P00846,P41440,Q99720,Q9NR77,Q9H6K4,P03886,O14773 10 +Central scotoma 0.8573236508950189 2.6424275655274485 0.008231407005433 1.0 0.0579910944550723 10 Q9H061,Q8NHS3,P03886,P00846 4 +Abnormal subcutaneous fat tissue distribution 0.8170265994873346 2.6409284267244004 0.0082679183849831 1.0 0.058032338705919 4 Q9BZK7 1 +Bile duct proliferation 0.7629865276071698 2.6356696659878733 0.0083971434098035 1.0 0.0585430873150412 3 Q9NSD9 1 +Broad chin 0.7085085732772609 2.622643311436748 0.0087250564282623 1.0 0.059795016066609 2 Q9H5V9 1 +Anomalous trichromacy 0.758252427184433 2.6128883798096294 0.0089780618923109 1.0 0.0609754428368347 3 O00429,Q9H6K4 2 +Tritanomaly 0.758252427184433 2.6128883798096294 0.0089780618923109 1.0 0.0609754428368347 3 O00429,Q9H6K4 2 +Retinal telangiectasia 0.8530641397896331 2.598601445847931 0.0093604382307721 1.0 0.0633823395895334 5 P03886 1 +Lateral clavicle hook 0.754438965945186 2.594489634889129 0.009473146991594 1.0 0.0636696674657583 3 Q9Y619 1 +Chromosomal breakage induced by crosslinking agents 0.7495145631067748 2.570667738498219 0.0101502658455585 1.0 0.0659214130541392 3 Q9BXW9,P13073 2 +Diastasis recti 0.800273829557778 2.564852535188111 0.0103219663139324 1.0 0.0666458542411814 4 Q8NCH0 1 +Abnormality of krebs cycle metabolism 0.8417912059368797 2.549650969302473 0.010783081301448 1.0 0.0690910301210176 5 P03886 1 +Nonketotic hypoglycemia 0.8415034987974082 2.548397760201785 0.0108219002783342 1.0 0.0692418195774779 5 P23786,P31751 2 +Abnormal muscle fiber morphology 0.4844971160474044 2.5332446517243 0.0113012045474445 1.0 0.0717009196077363 67 Q86U42,Q70HW3,Q9BQP7,Q99720,P61978,P23786,P50402,P03886,O75648,O43676,O95831,Q8WXH0,Q9BUK6,P50570,P00846,P00403,P51114,Q96RR1,Q96RL7,O14979,P07196 21 +Abnormal circulating citrulline concentration 0.836963423863224 2.5285961111099495 0.0114519726827291 1.0 0.0720899673349949 5 P03886,P00846 2 +Sensory ataxia 0.8354207355127361 2.521856594975821 0.0116737287911352 1.0 0.0722431576828452 5 Q9NR77,Q96RR1 2 +Vitreous floaters 0.7368361387990096 2.509006186492392 0.0121071363976681 1.0 0.0741153079478874 3 P04439 1 +Postural tremor 0.6719377680433616 2.508018602996874 0.0121410275060638 1.0 0.0741883271831433 20 Q9BRK0,P00846,Q9NR77,Q9H6K4,P03886,O14773 6 +Recurrent hand flapping 0.7365695792879896 2.5077046610947673 0.0121518187130005 1.0 0.0741883271831433 3 Q05086,Q06787 2 +Profound hearing impairment 0.8317227822789522 2.5056785661690153 0.0122216668675827 1.0 0.0743816626373289 5 Q9NR77 1 +Peroneal muscle atrophy 0.7360891081738914 2.5053581401033513 0.0122327458421214 1.0 0.0743816626373289 3 Q9NR77 1 +Abnormality of the extraocular muscles 0.6835975412487916 2.4937647747002964 0.0126396275754931 1.0 0.0746775542770216 2 Q9BVA1 1 +Giant platelets 0.6829505014558441 2.490389284503809 0.0127603245421379 1.0 0.0750704807479024 2 P35579 1 +Subependymal cysts 0.6816564218699535 2.4836340270341775 0.0130049385239581 1.0 0.0751208267404281 2 Q9BSJ2 1 +Reduced pancreatic beta cells 0.6816564218699446 2.4836340270341286 0.0130049385239598 1.0 0.0751208267404281 2 P40763 1 +Progressive pulmonary function impairment 0.7313915857605129 2.4823802472028555 0.0130507926368028 1.0 0.0751208267404281 3 Q12824,Q99496 2 +Neuralgia 0.7313915857605129 2.4823802472028555 0.0130507926368028 1.0 0.0751208267404281 3 Q12824,Q99496 2 +Decreased circulating follicle stimulating hormone concentration 0.7313915857605129 2.4823802472028555 0.0130507926368028 1.0 0.0751208267404281 3 Q12824,Q99496 2 +Hypothalamic hypothyroidism 0.7313915857605129 2.4823802472028555 0.0130507926368028 1.0 0.0751208267404281 3 Q12824,Q99496 2 +Ear pain 0.7313915857605129 2.4823802472028555 0.0130507926368028 1.0 0.0751208267404281 3 Q12824,Q99496 2 +Decreased pulmonary function 0.7313915857605129 2.4823802472028555 0.0130507926368028 1.0 0.0751208267404281 3 Q12824,Q99496 2 +Transient global amnesia 0.7313915857605129 2.4823802472028555 0.0130507926368028 1.0 0.0751208267404281 3 Q12824,Q99496 2 +Intracranial meningioma 0.7313915857605129 2.4823802472028555 0.0130507926368028 1.0 0.0751208267404281 3 Q12824,Q99496 2 +Visual acuity test abnormality 0.7313915857605129 2.4823802472028555 0.0130507926368028 1.0 0.0751208267404281 3 Q12824,Q99496 2 +Brain stem compression 0.7313915857605129 2.4823802472028555 0.0130507926368028 1.0 0.0751208267404281 3 Q12824,Q99496 2 +Hypoketotic hypoglycemia 0.8407109820496986 2.4528137788225295 0.014174369674313 1.0 0.0802623682807977 8 P49748,P23786,P31751,O43772 4 +Hypotriglyceridemia 0.6748625040439991 2.4480752112072435 0.0143621672008995 1.0 0.0802895415866231 2 Q10471 1 +Hypolipidemia 0.6748625040439991 2.4480752112072435 0.0143621672008995 1.0 0.0802895415866231 2 Q10471 1 +Amelogenesis imperfecta 0.7740369051472937 2.4442411256668186 0.0145157213153088 1.0 0.0802895415866231 4 Q9HC07,Q13586,Q6P4Q7 3 +Scotoma 0.7585105495201384 2.4437622901887535 0.0145349998751529 1.0 0.0802895415866231 13 Q9H061,Q8NHS3,P03886,P00846 4 +Ragged red muscle fibers 0.6738472494903699 2.4377727292025124 0.0147780618464194 1.0 0.0812434710731557 19 P00846,Q86U42,Q70HW3,Q9BQP7,Q96RR1,P03886,O95831 7 +Hypermetric saccades 0.7171521035598438 2.412325626735131 0.0158511176386342 1.0 0.0863047631045829 3 P18887,O14773 2 +Limited knee extension 0.6677450663215854 2.4106538106802797 0.0159239553364971 1.0 0.0863392126643081 2 Q9BPU6 1 +Laryngeal cleft 0.6667745066321662 2.4055374380842176 0.0161486972298658 1.0 0.0871260095879376 2 Q69YQ0 1 +Suicidal ideation 0.6667745066321629 2.4055374380842025 0.0161486972298665 1.0 0.0871260095879376 2 Q14203 1 +Abnormal circulating aromatic amino acid concentration 0.7155339805824891 2.4043264715753607 0.0162022964315151 1.0 0.0871260095879376 3 P35270,P61457 2 +Pleuritis 0.7150792329985661 2.4020770230814783 0.0163022754837416 1.0 0.0871260095879376 3 Q9NZ08 1 +Neuroinflammation 0.7150792329985661 2.4020770230814783 0.0163022754837416 1.0 0.0871260095879376 3 Q9NZ08 1 +Pulmonary embolism 0.7150792329985661 2.4020770230814783 0.0163022754837416 1.0 0.0871260095879376 3 Q9NZ08 1 +Orchitis 0.7150792329985661 2.4020770230814783 0.0163022754837416 1.0 0.0871260095879376 3 Q9NZ08 1 +Hypopigmentation of the fundus 0.7102675679785739 2.3782376650805257 0.017395609860767 1.0 0.0908905567119662 3 Q9Y619 1 +Abnormality of fundus pigmentation 0.7102675679785739 2.3782376650805257 0.017395609860767 1.0 0.0908905567119662 3 Q9Y619 1 +Impaired proprioception 0.5313640266127957 2.347087810400068 0.0189207950839864 1.0 0.0968488155146426 41 Q96RL7,P54802,P20700,Q9BRK0,P00846,P41440,O43819,Q9NR77,Q9Y619,Q9H6K4,Q96RR1,O14773,P07196 13 +Renal tubular atrophy 0.7515951040147251 2.339639462769973 0.0193023634183631 1.0 0.0984681377085415 4 P57740 1 +Flat forehead 0.7507872437406908 2.335849167962254 0.0194991040280119 1.0 0.0990257188866524 4 Q8NCH0,Q13555 2 +Basal ganglia cysts 0.8252563803035226 2.334192333844462 0.0195856531472717 1.0 0.0991696081451226 7 P23786 1 +Septate vagina 0.701294498381871 2.333594722244324 0.0196169532149017 1.0 0.0991794621244474 3 Q6W2J9,O60315 2 +Deformed tarsal bones 0.7003291418673712 2.328777426729564 0.0198708598525763 1.0 0.1002700624579357 3 O75787 1 +Increased cerebral lipofuscin 0.791734445636279 2.3286628223709895 0.019876935118593 1.0 0.1002700624579357 5 O75503,O14773 2 +Narrow iliac wing 0.6993527508090567 2.3239022113134813 0.0201307357267748 1.0 0.1007353567576991 3 P51812,Q9NR45 2 +Abnormal urine phosphate concentration 0.6992308784843516 2.323293489330138 0.0201633913438619 1.0 0.1007353567576991 3 P35670 1 +Hyperphosphaturia 0.6992308784843516 2.323293489330138 0.0201633913438619 1.0 0.1007353567576991 3 P35670 1 +Congenital hepatic fibrosis 0.7471910820680927 2.318955814462705 0.020397432270685 1.0 0.1013161931866262 4 Q8IY17 1 +Deep plantar creases 0.8309504258975534 2.311548198989046 0.0208025940966181 1.0 0.1020972386323727 6 Q9BZK7,Q9Y487 2 +Punctate cataract 0.744401015566019 2.3058255576723834 0.0211203815428224 1.0 0.1033210889729868 4 Q9H6K4 1 +Moderately reduced visual acuity 0.695469255663427 2.304483107193088 0.021195539550157 1.0 0.1034652954334175 3 O00429,O60313 2 +Focal tonic seizure 0.6467162730507942 2.2990736691725315 0.0215007563985429 1.0 0.104704944919953 2 Q00577 1 +Mitochondrial respiratory chain defects 0.8279631450104279 2.2987554327913617 0.0215188308433722 1.0 0.104704944919953 6 P03886,Q4J6C6 2 +Abnormal protein o linked glycosylation 0.6941747572815551 2.2979999709087933 0.0215617907830565 1.0 0.1048014079906074 3 Q15904,Q8N511 2 +Distal muscle weakness 0.4623713572053658 2.2935570979387956 0.0218159520898801 1.0 0.1056965379327884 61 Q13614,Q8IY17,P50570,P00846,P41440,Q99720,Q9NR77,Q9BQT8,O95831 9 +Abnormality of lower limb metaphyses 0.7837771396214044 2.2929833419866656 0.0218489640092836 1.0 0.1057433835064687 5 O95831 1 +Type ii transferrin isoform profile 0.74134023955974 2.2913975734600993 0.0219404297962531 1.0 0.1060727288975736 4 Q9UP83,O75787,Q9Y2V7 3 +Neoplasm of the tracheobronchial system 0.6441281138790067 2.2852354065695972 0.0222990281367516 1.0 0.1074623377228564 2 P30154 1 +Renal steatosis 0.6877431797507417 2.2657142878146677 0.0234688821696378 1.0 0.1123827021442488 3 P04114 1 +Bulbar signs 0.7574214385543736 2.2619951730096957 0.0236977015288371 1.0 0.1132390167991899 11 Q99720,P03886 2 +Abnormal csf protein level 0.7211927678442352 2.2552971421727563 0.0241146838972585 1.0 0.1141056174175012 13 Q16625,P03886 2 +Abnormality of the costochondral junction 0.6383047557424817 2.254014793978781 0.0241952373008176 1.0 0.1141056174175012 2 Q9Y3A5 1 +Proximal femoral metaphyseal irregularity 0.6383047557424817 2.254014793978781 0.0241952373008176 1.0 0.1141056174175012 2 Q9Y3A5 1 +Enlargement of the costochondral junction 0.6383047557424817 2.254014793978781 0.0241952373008176 1.0 0.1141056174175012 2 Q9Y3A5 1 +Abnormal monocyte morphology 0.6383047557424798 2.254014793978771 0.0241952373008182 1.0 0.1141056174175012 2 Q9UJV9 1 +Monocytosis 0.6383047557424798 2.254014793978771 0.0241952373008182 1.0 0.1141056174175012 2 Q9UJV9 1 +Abnormal circulating free fatty acid concentration 0.7334145423349998 2.253921667410876 0.0242010963173922 1.0 0.1141056174175012 4 P49748,Q16836 2 +Decreased circulating gonadotropin concentration 0.7316283586921605 2.245452858335616 0.0247390753387517 1.0 0.1158924625486852 4 Q12824,Q8IY17,Q99496 3 +Hemifacial spasm 0.7316283586921468 2.2454528583355504 0.0247390753387559 1.0 0.1158924625486852 4 Q12824,Q10713,Q99496 3 +Abnormal central sensory function 0.7316283586921369 2.245452858335502 0.024739075338759 1.0 0.1158924625486852 4 O75787,Q12824,Q99496 3 +Abnormal urinary color 0.7304075320390379 2.239659700604907 0.0251130237113332 1.0 0.1172449413740396 4 P23786 1 +Progressive visual field defects 0.6353930766742215 2.2383605999215863 0.0251975492080434 1.0 0.1172449413740396 2 O43395 1 +Severely reduced visual acuity 0.6353930766742208 2.2383605999215828 0.0251975492080436 1.0 0.1172449413740396 2 Q13277 1 +Germinoma 0.6353930766742186 2.2383605999215725 0.0251975492080442 1.0 0.1172449413740396 2 Q14145 1 +Pilomatrixoma 0.6353930766742186 2.2383605999215725 0.0251975492080442 1.0 0.1172449413740396 2 Q14145 1 +Small epiphyses 0.7291526469812603 2.233700806986896 0.0255027658738997 1.0 0.1181263081889222 4 O95831 1 +Blurred vision 0.7702230558289267 2.231859883203027 0.0256242250195517 1.0 0.1185676602028288 5 P03886 1 +Coxa vara 0.6870326501402735 2.2304552529457857 0.0257172349542931 1.0 0.1188766064723957 15 Q96HY6,Q99575,Q9NUQ7,Q9Y487,Q96AY3,O95831 6 +Muscle stiffness 0.6115746004349345 2.224176264314828 0.0261365873516503 1.0 0.1200798587251279 21 P49748,Q9BRK0,P00846,Q15392,P23786 5 +Widow s peak 0.7248135145872989 2.2130640125084873 0.0268932327498014 1.0 0.1226851403389735 4 P29372 1 +Mitochondrial inheritance 0.7652536806567563 2.2093399284770725 0.0271510059220092 1.0 0.1236121174137707 5 P03886 1 +Abnormal upper motor neuron morphology 0.7741462979698019 2.207231744546729 0.0272978730602653 1.0 0.1241559889186766 9 Q99720 1 +Chromosomal breakage induced by ionizing radiation 0.7219164778245357 2.199258010270283 0.0278595815797502 1.0 0.125576024434098 4 Q969G3,Q12824,Q99496 3 +Absent brainstem auditory responses 0.6734627831715093 2.19358272895585 0.028265421165101 1.0 0.1269459338152356 3 O60313,P07196 2 +Eeg with irregular generalized spike and wave complexes 0.6266580394694322 2.191222553846649 0.0284356912573047 1.0 0.1269459338152356 2 P11166 1 +Generalized myoclonic atonic seizure 0.6266580394694322 2.191222553846649 0.0284356912573047 1.0 0.1269459338152356 2 P11166 1 +Eeg with focal spike waves 0.6266580394694322 2.191222553846649 0.0284356912573047 1.0 0.1269459338152356 2 P11166 1 +Choroidal melanoma 0.6253639598835392 2.1842167725949424 0.0289463230192119 1.0 0.1278039408158189 2 Q99496 1 +Abnormal ciliary body morphology 0.6253639598835392 2.1842167725949424 0.0289463230192119 1.0 0.1278039408158189 2 Q99496 1 +Mydriasis 0.6253639598835392 2.1842167725949424 0.0289463230192119 1.0 0.1278039408158189 2 Q99496 1 +Lens subluxation 0.6253639598835392 2.1842167725949424 0.0289463230192119 1.0 0.1278039408158189 2 Q99496 1 +Ocular pain 0.6253639598835392 2.1842167725949424 0.0289463230192119 1.0 0.1278039408158189 2 Q99496 1 +Inferior lens subluxation 0.6253639598835392 2.1842167725949424 0.0289463230192119 1.0 0.1278039408158189 2 Q99496 1 +Metamorphopsia 0.6253639598835392 2.1842167725949424 0.0289463230192119 1.0 0.1278039408158189 2 Q99496 1 +Uveal melanoma 0.6253639598835392 2.1842167725949424 0.0289463230192119 1.0 0.1278039408158189 2 Q99496 1 +Photopsia 0.6253639598835392 2.1842167725949424 0.0289463230192119 1.0 0.1278039408158189 2 Q99496 1 +Abnormal chromosome morphology 0.6243934001941197 2.178958652196463 0.029334739981548 1.0 0.1290158952586529 2 Q6NZY4 1 +Abnormal circulating ceruloplasmin concentration 0.715468905115026 2.1684519738378984 0.0301243149253556 1.0 0.1310885173985215 4 O00400,Q8N511 2 +Proximal femoral metaphyseal abnormality 0.6678382825201683 2.165004324295365 0.0303873541139252 1.0 0.1316637921678823 3 Q9NUQ7 1 +Upper limb postural tremor 0.667652024700595 2.1640563112128106 0.030460027943358 1.0 0.1317321054723468 3 Q9NR77 1 +Occipital meningocele 0.7531036075709827 2.154030572984711 0.0312377743983334 1.0 0.1340454349318401 5 Q92766,Q10713 2 +Inappropriate antidiuretic hormone secretion 0.618246522161118 2.145581967736919 0.0319063453762644 1.0 0.1360976879044049 2 Q13724 1 +Abnormal circulating acetylcarnitine concentration 0.7796481691857196 2.133356625214457 0.0328954823523361 1.0 0.1391377544874724 7 P23786 1 +Renal cortical microcysts 0.615658362989329 2.131489790992584 0.0330488126095505 1.0 0.1396558965683431 2 Q8TD19 1 +Amyotrophic lateral sclerosis 0.6948959265092913 2.1200447702759173 0.0340022698979507 1.0 0.143135598529847 13 Q99720,Q15165 2 +Demyelinating peripheral neuropathy 0.666255627567778 2.11752695489805 0.0342151501252143 1.0 0.1432482717811655 15 P41440,Q9NR77,P03886 3 +Hyperplasia of the maxilla 0.6124231640245915 2.113842270453819 0.0345287412829578 1.0 0.1440287274510118 2 Q96CW1 1 +Muscle weakness 0.3203461817354832 2.1089810610963324 0.0349462164097764 1.0 0.1446695261162161 288 Q13614,Q9P0J0,Q13126,Q86U42,Q70HW3,Q99720,Q9BQP7,Q9NWM8,P61978,Q4J6C6,Q15165,P23786,Q9BZK7,O43772,Q96B26,P03886,Q9HC07,Q9BUF5,Q8NC96,Q9NQT5,O96000,P49748,O75648,P20700,P41440,Q6DKK2,Q9NR77,Q96TA2,Q5XKP0,O96011,Q9Y375,Q9UNW1,P13073,O43681,Q8NCH0,O95831,Q8N0X7,Q5KU26,O95817,P50570,P00846,P51970,Q96F07,Q96CU9,Q92804,Q96RR1,Q96RL7,Q8IY17,Q71SY5,O43819,Q10713,Q9BQT8,P07196 53 +Hypothermia 0.7089161300606077 2.105695409424791 0.0352308188515806 1.0 0.1452189348477345 12 P49748,O43772,P03886,P00846 4 +Macrovesicular hepatic steatosis 0.7725210628645391 2.101553134208233 0.0355924388899269 1.0 0.1464430046969745 7 O75648,Q96AX1,Q5XKP0,P23786,Q9Y375,O75431 6 +Episodic vomiting 0.6730623269433696 2.0962364800167026 0.0360612183509923 1.0 0.1476006618510065 14 P49748,Q9Y619,P03886,P00846 4 +Decreased circulating copper concentration 0.6511053876682894 2.079422671048178 0.0375785185285126 1.0 0.1525991656185713 3 Q14746 1 +Corneal neovascularization 0.6946187503624534 2.068081069097422 0.038632400519619 1.0 0.1548511916004873 4 Q92766 1 +Hypertensive crisis 0.6946187503624534 2.068081069097422 0.038632400519619 1.0 0.1548511916004873 4 Q92766 1 +Tricuspid atresia 0.6946187503624534 2.068081069097422 0.038632400519619 1.0 0.1548511916004873 4 Q92766 1 +Multiple suture craniosynostosis 0.6946187503624534 2.068081069097422 0.038632400519619 1.0 0.1548511916004873 4 Q92766 1 +Axonal degeneration 0.7738705629531444 2.063771380423302 0.0390393978151366 1.0 0.1550653250668645 6 Q6DKK2,Q9BQT8 2 +Duodenal adenocarcinoma 0.6023940472339109 2.05890765437001 0.0395030856924463 1.0 0.1565334897041357 2 P78549 1 +Adenocarcinoma of the small intestine 0.6023940472339109 2.05890765437001 0.0395030856924463 1.0 0.1565334897041357 2 P78549 1 +Heparan sulfate excretion in urine 0.6461127077854514 2.0537254529488544 0.0400022716092809 1.0 0.1572629274259566 3 P54802 1 +Ventricular arrhythmia 0.5281788178447476 2.0381044737908103 0.0415394858554434 1.0 0.1611077662030468 34 P49748,Q8WXH0,P00846,Q8NFF5,P00403,Q96AX1,P23786,P50402,O43772,P21912,P03886,Q96RR1,P42892,P04899 14 +Pulmonary edema 0.6409233832333219 2.0269378455125824 0.0426687695074359 1.0 0.1648688399527444 3 Q13724 1 +Choroid plexus carcinoma 0.6403868136386712 2.0241635055969325 0.0429533311791887 1.0 0.1657398554018101 3 Q12824 1 +Deep palmar crease 0.708386538462546 2.023148603693953 0.0430578287793248 1.0 0.1658450300562872 11 P61978,Q96AX1,Q9BZK7,Q9Y487,Q69YQ0,O75431 6 +Abnormality of the crus of the helix 0.6401294498381729 2.0228325017991837 0.0430904195091059 1.0 0.1658450300562872 3 Q7LGA3,Q9H5V9 2 +Abnormality of cartilage of external ear 0.6401294498381729 2.0228325017991837 0.0430904195091059 1.0 0.1658450300562872 3 Q7LGA3,Q9H5V9 2 +Hypoplasia of the musculature 0.7240396659386069 2.0203054611213607 0.0433517126963947 1.0 0.1664264902666678 5 Q9NR77 1 +Rhabdomyolysis 0.6475892553772541 2.0148971318011655 0.0439154285985001 1.0 0.1678131999243285 15 P23786,O43772,Q86VD7 3 +Abnormal rib ossification 0.6385113268608447 2.014459617432188 0.0439613005450443 1.0 0.1678131999243285 3 Q9Y3A5,Q14739 2 +Abnormal speech prosody 0.7425758407363132 2.0118897639962623 0.0442315586555515 1.0 0.1678131999243285 8 P03886 1 +Pendular nystagmus 0.7512033177139424 2.005757721741089 0.0448821034251465 1.0 0.1699965957490918 7 Q9BZK7,P00846 2 +Polyphagia 0.7603407121410364 2.0040156674052594 0.045068382145516 1.0 0.1705595414529553 6 Q4J6C6 1 +Abnormal neuron morphology 0.5589770992808758 2.003304006604123 0.0451446677106519 1.0 0.1707056299910295 24 Q99720,Q8IY17,Q15165 3 +Irregular epiphyses 0.6810979497132947 2.0023854511650248 0.0452432919937673 1.0 0.1709358738380032 4 Q9NUQ7 1 +Hyperventilation 0.7574163491242032 1.991049214564296 0.046475476925569 1.0 0.1737078469247755 6 P03886 1 +Pain 0.3671848259935812 1.9853265709146988 0.0471081496606964 1.0 0.1753491519827073 167 Q70HW3,Q15165,P23786,Q9BZK7,Q9NZ08,Q14108,P42892,P49748,Q9NR77,P28070,Q9UNW1,Q96HY6,Q9BRK0,P50570,P00846,Q92804,Q96RR1,P48735,Q13423,Q14C86,Q9H6K4,Q9NUQ7 22 +Nemaline bodies 0.6773976919380611 1.984324034080101 0.0472197285570161 1.0 0.17547610366143 4 P07196,O43676 2 +Abnormality of chorioretinal pigmentation 0.6771467940345776 1.9830980967786205 0.0473564731649021 1.0 0.175840019210661 4 Q5XKP0,Q9Y619 2 +Barrel shaped chest 0.6765082484463567 1.979977307198457 0.0477060786460821 1.0 0.1766182074517046 4 Q32P28 1 +Heat intolerance 0.6756110073896344 1.975590419391078 0.048201184607975 1.0 0.1775214359952252 4 Q05086 1 +Nephropathy 0.6154677973493176 1.9550596460054404 0.0505760305742095 1.0 0.1834342822267168 17 P00403,P57740,P03886,Q10713,Q14108,Q9H267 6 +Vitreous hemorrhage 0.6255663430420746 1.9472007560766065 0.0515106710944188 1.0 0.186227725504962 3 P35222,Q99496 2 +Right ventricular hypertrophy 0.6249890061597376 1.9441897168188096 0.0518725773767283 1.0 0.1868393932329746 3 Q9H267 1 +Atrophy degeneration involving the caudate nucleus 0.7073264473783297 1.9425119947618583 0.0520751492862938 1.0 0.1872190820580997 5 P00846 1 +Reduced circulating prolactin concentration 0.6687910495182244 1.942178371458846 0.0521155104801907 1.0 0.1872190820580997 4 Q12824,Q99496 2 +Unsteady gait 0.4654487066223054 1.9265850452618705 0.0540313638421872 1.0 0.1925744124351755 46 O95319,Q96F07,Q9NR77,Q5JRX3,O75503,Q9H6K4,Q10713,Q8NC96,O95831,P07196,P49366 11 +Abnormal circulating bilirubin concentration 0.5343358087192978 1.9161396809986289 0.0553473186439932 1.0 0.1960307689267312 28 P41440,P23786,Q9NSD9 3 +Abnormal visual field test 0.701353955454416 1.914556909619125 0.0555490348939884 1.0 0.1962848112868702 5 Q99496,Q12824,P00846 3 +Pain in head and neck region 0.6623973197053509 1.9107474063991936 0.056037049427462 1.0 0.1977008052230552 4 Q12824,Q99496 2 +Obsessive compulsive trait 0.7001295336787553 1.908815838072335 0.0562858529933425 1.0 0.1982596997441378 5 Q93009,Q06787,Q8WXI9,O75503 4 +Impaired vibratory sensation 0.518298273657952 1.9023409771793691 0.057126591863432 1.0 0.1999872188109329 32 Q96RL7,Q9BRK0,P20700,P00846,O43819,Q9NR77,Q9Y619,Q96RR1,O14773,P07196 10 +Vasculitis 0.6974772315297255 1.896368121253429 0.0579113841997753 1.0 0.2016437897194331 5 Q9NZ08,Q8NBM4 2 +Lacticaciduria 0.735811602484451 1.8947042049913416 0.0581316003512002 1.0 0.2019448999930499 6 P03886,Q9BQT8,P00846 3 +Increased serum pyruvate 0.500009809003154 1.8882916977005084 0.0589868012754186 1.0 0.2038216703109432 36 Q9BWD1,Q70HW3,Q96CU9,Q9Y375,P03886,Q96RR1,O95831 7 +Optic disc coloboma 0.6534456879709349 1.8665701173032512 0.0619616438727028 1.0 0.2102518702197333 4 Q10713,P78318 2 +Hemoptysis 0.6526257346098407 1.8625136329180263 0.0625307256277616 1.0 0.2117071652419732 4 Q9NZ08 1 +Abnormal circulating carbohydrate concentration 0.4726139099737144 1.8583441117457835 0.0631201633781335 1.0 0.2129501658272839 41 Q9BWD1,Q70HW3,Q96CU9,Q9Y375,P03886,Q96RR1,O95831 7 +Flared iliac wing 0.6514400543059561 1.8566448963805977 0.0633616919797881 1.0 0.2134040629505132 4 O95831 1 +Recurrent fever 0.6441817496006386 1.8536109212670424 0.0637948440042244 1.0 0.214384750251585 13 P28070,Q9NR77,P61978,Q9Y2V7 4 +Oromandibular dystonia 0.6877411522494767 1.8505401187967243 0.0642357412888574 1.0 0.2152277426320445 5 Q99720 1 +Moderate albuminuria 0.6070598009818324 1.8502081429758723 0.0642835557717917 1.0 0.2152287565751787 3 P40763 1 +Progressive visual loss 0.5404790240176804 1.8454613307867125 0.0649704586150174 1.0 0.2169020012661156 22 Q8IY17,P00846,O75503,P03886,O14773 5 +Goiter 0.6969969189051602 1.8451018844783256 0.0650227191433521 1.0 0.2169020012661156 9 P48735,Q9UNW1 2 +Tachycardia 0.5403271419337574 1.8444436416482364 0.0651185121155331 1.0 0.217061707051777 22 P23786,P42892,O43772 3 +Abnormal circulating non proteinogenic amino acid concentration 0.7150295915781624 1.840961204130012 0.0656272441952698 1.0 0.2182756359798623 7 P03886,P00846 2 +Undetectable electroretinogram 0.6478550982821271 1.8388795840028345 0.0659328992905261 1.0 0.2188102811619659 4 O14773 1 +Slow decrease in visual acuity 0.6943383639336064 1.8323797409313471 0.0668948642279243 1.0 0.2203881708745435 9 P03886 1 +Equinovarus deformity 0.7123754597860595 1.82876192183688 0.0674352816302841 1.0 0.2215241666317527 7 Q9NR77 1 +Cognitive impairment 0.3585579712482186 1.828415197207901 0.0674872622778728 1.0 0.2215342739991042 158 Q99720,O15118,Q9NZ08,P03886,Q14108,P50897,Q8NC96,Q03164,Q8NHS3,P20700,Q6DKK2,Q5XKP0,Q9Y487,O96011,O95470,O43681,Q8N0X7,O95831,Q9BRK0,P54802,P00846,O43464,O75381,Q96F07,O75503,Q96RR1,Q12824,Q96RL7,O95319,Q8IY17,O43819,Q9Y619,Q9H6K4,Q9UQE7,Q9UEY8,P57740,Q10713,P21964,P07196 39 +Uncombable hair 0.5583953413134997 1.8139286896447528 0.0696887051223962 1.0 0.2266259990206259 2 Q6PGP7 1 +Trichorrhexis nodosa 0.5583953413134997 1.8139286896447528 0.0696887051223962 1.0 0.2266259990206259 2 Q6PGP7 1 +Urinary bladder sphincter dysfunction 0.6904849401481439 1.8139123282375311 0.0696912244201271 1.0 0.2266259990206259 9 Q9NR77 1 +Reduction of neutrophil motility 0.5999999999999972 1.8129545679368588 0.0698388288372613 1.0 0.2266259990206259 3 Q9Y3A5,P61011 2 +Deformed rib cage 0.5999999999999972 1.8129545679368588 0.0698388288372613 1.0 0.2266259990206259 3 Q9Y3A5,P61011 2 +Abnormality of vitamin k metabolism 0.5999999999999972 1.8129545679368588 0.0698388288372613 1.0 0.2266259990206259 3 Q9Y3A5,P61011 2 +Abnormality of vitamin e metabolism 0.5999999999999972 1.8129545679368588 0.0698388288372613 1.0 0.2266259990206259 3 Q9Y3A5,P61011 2 +Focal cortical dysplasia 0.5580718214170255 1.8121041250433003 0.0699701091285098 1.0 0.2268658098076994 2 Q8WUM0 1 +Saccadic smooth pursuit 0.6771762062260769 1.8005746054728125 0.0717699547493486 1.0 0.230529948947925 5 O14773 1 +Cardiac conduction abnormality 0.5210990010187794 1.8003509248184293 0.0718052445840005 1.0 0.230529948947925 27 P49748,P00846,O43819,P23786,O43772,P03886 6 +Dysesthesia 0.7138969935909909 1.796010210859197 0.072492893109848 1.0 0.2310233362601009 6 Q9NR77 1 +Peripheral demyelination 0.5876322741213652 1.7916436910867568 0.0731900597221992 1.0 0.2320160745567268 17 P20700,P50570,P00846,Q9NR77,P03886,P07196 6 +Ependymoma 0.5957980600397812 1.790716744712808 0.0733387612540126 1.0 0.2323248870494245 3 P42771 1 +Abnormal astrocyte morphology 0.6070014087053595 1.788033176356351 0.0737706554309862 1.0 0.2328787937995594 15 O95831,P00846 2 +Small earlobe 0.6729716434754155 1.780622683268952 0.0749741115835198 1.0 0.2355876307516781 5 Q92766,P21964 2 +Personality changes 0.6451182225729715 1.7790413411308528 0.075232984454959 1.0 0.23605222391091 12 Q96RL7,Q8IY17,P20700,P35670,P00403,P03886 6 +Visual loss 0.4464826544382114 1.778817573123935 0.0752696751608281 1.0 0.23605222391091 47 Q8NHS3,Q8IY17,P00846,Q6W2J9,P48449,O75503,P36405,P03886,Q10713,P50897,O14773,Q92734,Q12824,P04439,P52732 15 +Toxemia of pregnancy 0.7100639506956611 1.7786509111281237 0.0752970118214713 1.0 0.23605222391091 6 O43772 1 +Persistent head lag 0.7089266050136205 1.773494609198588 0.0761467843758323 1.0 0.238221638965829 6 Q9NSD9 1 +Cogwheel rigidity 0.7083879889087225 1.7710518622005011 0.0765520778663386 1.0 0.2391592501617338 6 Q96RR1,P00846 2 +Abnormal circulating copper concentration 0.6992453227233565 1.7682023208084563 0.0770270863633304 1.0 0.2396515805122849 7 P35670,Q9Y487,Q14746,O43819 4 +Somatic sensory dysfunction 0.3869503440450268 1.7481679728889297 0.0804349456222011 1.0 0.2466962110146046 100 Q13614,P61978,Q9NZ08,Q13045,P41440,Q9NR77,O14773,Q8NCH0,O95831,O95817,Q9BRK0,P54802,P50570,P00846,Q96RR1,Q96RL7,Q71SY5,O43819,Q9Y619,Q9H6K4 20 +Cerebral calcification 0.5001445932360071 1.7397330110684155 0.0819059100064962 1.0 0.2495575892837937 31 P23786,Q16625,P03886 3 +Migraine 0.5223342825930007 1.73770437735762 0.0822629170252762 1.0 0.2495575892837937 23 Q8NBM4,Q13586,P00403,O60313,O43791,O00429,Q9NZ08,O96011,P03886,Q96RR1,Q12824 11 +Abnormality of temperature regulation 0.3904735714656294 1.7323823247615449 0.0832055129011128 1.0 0.2512806489613609 95 P49748,P50570,P00846,Q14C86,Q9NR77,P61978,Q05086,P23786,P28070,O43772,Q9BZK7,P03886,Q9NZ08,Q5XKP0,Q9Y2V7 15 +Polyneuropathy 0.5455773608512106 1.7283835363970876 0.0839194851668942 1.0 0.2527628110412441 20 O95831,P03886 2 +Morphological abnormality of the pyramidal tract 0.5204819717919961 1.7250432503106106 0.0845196784453528 1.0 0.2542324989093281 23 O95831,Q13045,P00846 3 +Abnormality of the mitochondrion 0.3870706344146191 1.7238988596419127 0.0847261032394013 1.0 0.254684305026203 98 P49748,Q9P0J0,Q7KZN9,P00846,Q70HW3,Q9BQP7,Q4J6C6,Q96CU9,P23786,Q9Y584,O43772,Q9Y375,P03886,Q96RR1,P13073,O96000 16 +Abnormal renal tubule morphology 0.5327719132350639 1.7169569781885996 0.0859870329457339 1.0 0.2577903767334049 21 O43819,P00846,P23786,P57740,P03886 5 +Prominent nasolabial fold 0.6943922334519638 1.7073867627088108 0.0877501891181795 1.0 0.262035831710846 6 Q9Y487 1 +Abnormality of the nasolabial region 0.6943922334519638 1.7073867627088108 0.0877501891181795 1.0 0.262035831710846 6 Q9Y487 1 +Chorea 0.4011371907764414 1.7055765670335985 0.0880869453424297 1.0 0.2627443726767577 80 Q96RL7,Q9BWD1,P00846,O43819,Q9UBB6,Q99720,Q9H6K4,Q5XKP0,P03886,Q08J23,Q9NUQ7,Q86VD7 12 +Muscle fiber atrophy 0.5419604154277997 1.7051767373236162 0.0881614672116273 1.0 0.2627443726767577 20 Q96RL7,P23786,Q99720 3 +Impaired distal vibration sensation 0.6931207321783336 1.7015849250878583 0.0888332054219183 1.0 0.2643984366368528 6 Q96RR1,Q9BRK0 2 +Cerebral palsy 0.6423164581122655 1.6917608009019858 0.0906915903878797 1.0 0.2684993475836402 11 P48735,O75874,P61457,Q9BVA1,P98175,Q12824 6 +Paresthesia 0.5398294339178307 1.6914835787189195 0.0907444814901883 1.0 0.2684993475836402 20 P54802,Q9NR77,Q9H6K4,Q9NZ08,P07196 5 +Hemianopia 0.6722787191181568 1.682764083933294 0.0924207704275383 1.0 0.2718306195128478 8 P00403,Q9BVA1,P03886,Q12824,Q99496 5 +Progressive gait ataxia 0.611640874159715 1.6789918370539283 0.0931536346598038 1.0 0.273315225032585 13 Q05086,O14773,P00846 3 +Spondyloepimetaphyseal dysplasia 0.6800315390836243 1.6789774042689152 0.0931564475607751 1.0 0.273315225032585 7 Q96HY6,O95831,Q9NR45 3 +Myositis 0.6709987063060106 1.67667727347824 0.0936056070451627 1.0 0.2741004524334759 8 P28070,Q9NZ08,Q8NBM4 3 +Inflammation of the large intestine 0.6392170765271172 1.6759661251196074 0.0937448280364061 1.0 0.2743307952228165 11 P49748,P08183 2 +Abnormal acetabulum morphology 0.567903406240543 1.6743561907062865 0.0940606173019724 1.0 0.2747224992765539 17 O75718,Q9NR45,Q9Y584,Q96AY3,Q9NUQ7 5 +Motor neuron atrophy 0.5473625912813908 1.6723843082181458 0.0944485643616983 1.0 0.2754934864390078 19 Q99720,Q15165 2 +Episodic tachypnea 0.6853695409991233 1.6661536265159578 0.0956828197251415 1.0 0.2785624507422181 6 P49748,Q10713 2 +Metaphyseal dysplasia 0.6486155853536418 1.656415088151011 0.0976377876466647 1.0 0.2817864366112386 10 O95831,Q99575,Q9NUQ7 3 +Optic disc pallor 0.4225536806498934 1.6562999882361953 0.0976610828873387 1.0 0.2817864366112386 51 Q8NHS3,P00846,Q9H061,Q9H6K4,Q96CU9,Q9Y375,P03886,Q10713,O96000,O95831 10 +Abnormal intraocular pressure 0.6464807708521292 1.6540744259896418 0.0981123915578039 1.0 0.2829084237790272 5 Q8NCH0,P04439 2 +Occipital encephalocele 0.6099498106343358 1.6491905356485344 0.0991086062821717 1.0 0.284874356889745 4 Q10713 1 +Agyria 0.5689320388349555 1.647439233592117 0.099467796718029 1.0 0.2853635966641366 3 O00139,P43034 2 +Delayed ability to roll over 0.6428517435845774 1.636630132611418 0.1017077755537982 1.0 0.2910525731261568 5 Q5BJH7 1 +Variable expressivity 0.3972792029361645 1.6330292863913187 0.1024628373683274 1.0 0.2928433143713079 75 P07196,Q9UBQ7,Q70HW3,Q9H061,Q9NR77,Q6P4A7,P57740,Q9UEY8,Q9Y375,P03886,Q9BUF5,Q9NQT5,O95470,P52732,O60762 15 +Clumsiness 0.530514833003178 1.6314568790477209 0.1027939515057894 1.0 0.2936044138217061 20 Q9NR77,O75503,Q05086,Q96RR1,O14773 5 +Ventricular tachycardia 0.6302100403558686 1.6299504882585434 0.1031119616922484 1.0 0.2941655558072687 11 P49748,P23786,O43772 3 +Onion bulb formation 0.6760869839891811 1.6235841208828776 0.1044645966792598 1.0 0.2974384808026696 6 Q9NR77,P50570 2 +Mixed demyelinating and axonal polyneuropathy 0.6398505363066673 1.622184956447922 0.1047637517807433 1.0 0.2981028866625424 5 P00403,P03886,P07196 3 +Long eyelashes 0.4535041929760481 1.616689912886041 0.1059452323855376 1.0 0.3012755195897587 39 Q8IY17,Q9Y619,Q96AX1,Q4J6C6,O43791,Q9UQE7,P38398,Q12824,Q03164,Q5KU26,Q92974 11 +Basal ganglia calcification 0.6740519920445839 1.614232176197589 0.1064770752187287 1.0 0.3025979615689091 6 O00429,P03886,P00403,Q9Y3Z3 4 +Impaired vibration sensation in the lower limbs 0.5763664297980925 1.6136790531094591 0.1065970597542769 1.0 0.3027490161046234 15 Q9NR77,Q9BRK0,P00846 3 +Clubbing of toes 0.6365305999387633 1.6061862856027127 0.1082329857365267 1.0 0.3064346408665412 5 Q9Y2B2,P38398,Q9BXW9 3 +Postural instability 0.5556837432864412 1.6011510475636543 0.1093434681343943 1.0 0.3088066774618493 17 P41440,Q9NR77,O75503 3 +Panniculitis 0.6703272471364577 1.5970971280665944 0.1102440582736326 1.0 0.3103825879301154 6 P28070,P52732 2 +Hammertoe 0.5339814465196132 1.5881401832865714 0.1122546435793476 1.0 0.3136257001532118 19 Q99720 1 +Duodenal stenosis 0.5978203252525721 1.5878241091477512 0.1123261181554819 1.0 0.3136257001532118 4 Q9BXW9,P38398 2 +Pyridoxine responsive sideroblastic anemia 0.5978203252525721 1.5878241091477512 0.1123261181554819 1.0 0.3136257001532118 4 Q9BXW9,P38398 2 +Lung adenocarcinoma 0.5578188327836316 1.587651197303759 0.112365234293303 1.0 0.3136257001532118 3 Q99496 1 +Psychomotor deterioration 0.6422948387577444 1.5803798647169578 0.1140198999111974 1.0 0.3178523979062919 9 Q9Y487,Q03164 2 +Chorioretinal coloboma 0.6655948956692532 1.5752943412189788 0.1151885195593722 1.0 0.3209126651930851 6 Q6W2J9,Q10713,O60826 3 +Thick hair 0.653316167589832 1.5538082121802954 0.1202301710908351 1.0 0.3322683268473161 7 Q9UQE7,Q9Y487,Q96AX1 3 +Tinnitus 0.5873087845426657 1.5467624996562586 0.1219205259571327 1.0 0.3353209370102289 13 Q9NR77 1 +Multifactorial inheritance 0.6139717192144977 1.546580733565013 0.1219643785019617 1.0 0.3353209370102289 11 P42892,P38398,P10321 3 +Retinopathy 0.4802784628475864 1.5458495723600778 0.1221409016451635 1.0 0.3353209370102289 29 Q8NHS3,P00846,O43819,P07437,Q9NZ08,Q9Y375,O96028,P52732,O60762 9 +Intestinal pseudo obstruction 0.6264290401177879 1.54571614581907 0.1221731361480285 1.0 0.3353209370102289 10 P00403,P61978,Q96RR1,P38398,P03886 5 +Abnormality of the parathyroid gland 0.5272208833154054 1.5453825928258096 0.1222537482656047 1.0 0.3353209370102289 19 P48735,Q92766,Q96DF8,P00403,P03886,P21964,Q08J23 7 +Fatiguable weakness of proximal limb muscles 0.6238603028658811 1.5449480403979714 0.1223588319818782 1.0 0.3353209370102289 5 Q92734,Q9Y281,Q13586 3 +Pancreatic fibrosis 0.5101908767389312 1.5386800174451898 0.123882433022024 1.0 0.338472510005892 2 Q96J42 1 +Generalized limb muscle atrophy 0.6416349467910564 1.5362334982377377 0.1244811230059257 1.0 0.3394939718343429 8 Q8IY17 1 +Abnormal circulating protein concentration 0.3408529660857077 1.532648013379912 0.1253626046221398 1.0 0.3406002519592859 143 Q86U42,Q9BQP7,Q5JRX3,Q9NWM8,P23786,O43772,Q9HC07,Q08J23,O14653,P49748,O75648,P41440,Q96AX1,Q5XKP0,Q9Y487,O95470,O95831,O95817,P50570,Q9Y584,Q9NSD9,Q96RR1,Q9Y2V7,O60762,Q86VD7,Q96RL7,P83436,P50416,Q14C86,P57740,P07196 31 +Broad alveolar ridges 0.5082497573600882 1.5274655639714996 0.1266452838833305 1.0 0.3428778914014537 2 Q9UBM7 1 +Anterior open bite malocclusion 0.5082497573600785 1.527465563971444 0.1266452838833442 1.0 0.3428778914014537 2 P08754 1 +Impaired distal tactile sensation 0.5076027175671398 1.5237254316788909 0.1275773137609563 1.0 0.3440031138911502 2 O15270 1 +Penetrating foot ulcers 0.5076027175671398 1.5237254316788909 0.1275773137609563 1.0 0.3440031138911502 2 O15270 1 +Emg slow motor conduction 0.5076027175671398 1.5237254316788909 0.1275773137609563 1.0 0.3440031138911502 2 O15270 1 +Trophic changes related to pain 0.5076027175671398 1.5237254316788909 0.1275773137609563 1.0 0.3440031138911502 2 O15270 1 +Gait ataxia 0.3889115900547672 1.52138225391699 0.1281639395691354 1.0 0.3447640417150732 67 Q8IY17,P00846,P41440,Q9NR77,O15118,Q05086,Q96RR1,P03886,Q10713,O14773 10 +Response to drugs acting on neuromuscular transmission 0.5069556777741887 1.5199843191508935 0.1285149167412542 1.0 0.3450934041718327 2 Q9H553 1 +Single fiber emg abnormality 0.5069556777741887 1.5199843191508935 0.1285149167412542 1.0 0.3450934041718327 2 Q9H553 1 +Emg decremental response of compound muscle action potential to repetitive nerve stimulation 0.5069556777741887 1.5199843191508935 0.1285149167412542 1.0 0.3450934041718327 2 Q9H553 1 +Corneal erosion 0.5063086379812414 1.5162422326824594 0.1294581126989125 1.0 0.3468038146221606 2 P51648 1 +Reduced tendon reflexes 0.338475166099185 1.512161329505616 0.130492825972823 1.0 0.3491627298623087 163 Q9Y3B2,Q99720,Q9BQP7,P61978,P03886,Q8NC96,Q96AY3,P04114,O14653,O75648,Q13045,P41440,Q9NR77,Q96AX1,O96011,O43681,O95831,Q8WXH0,O95817,Q92974,Q9Y2B2,P54802,P50570,P00846,O75381,Q96F07,Q96RR1,Q96RL7,P83436,O95319,Q8IY17,Q71SY5,O43819,P50416,Q9H6K4,Q10713,Q9BQT8,P07196 38 +Cough 0.4808809353096973 1.511793582164565 0.1305863825980389 1.0 0.3492067964398561 27 P41440,Q9NR77,Q9NSD9 3 +Hypoparathyroidism 0.5668935144584182 1.5109510780966036 0.1308009156931118 1.0 0.3495741286665466 14 Q92766,Q96DF8,P00403,P03886,P21964,Q08J23 6 +Right ventricular dilatation 0.5050145583953537 1.5087551634272305 0.1313613626630099 1.0 0.3505073555016304 2 Q7Z392 1 +Increased muscle glycogen content 0.5418651495356728 1.5013434288506171 0.1332667576877142 1.0 0.35377780815161 3 O75648 1 +Dysdiadochokinesis 0.56500572038695 1.5002871190681992 0.1335400446093055 1.0 0.35377780815161 14 P20700,P41440,Q6DKK2,O75503,P18887 5 +Chromosome breakage 0.6042348046166767 1.4963562325857926 0.1345608485512868 1.0 0.3560517780007764 11 Q969G3,Q9BXW9,Q9NVI1,Q06787,P38398,P13073,Q12824,P33991,Q99496 9 +Pancreatic islet cell hyperplasia 0.5024263992235607 1.4937696218386605 0.1352358441155816 1.0 0.3576289397802596 2 Q14739 1 +Rigidity 0.4053620807946565 1.4893249617232849 0.1364018176561563 1.0 0.3602916816223838 51 O95319,O75787,Q9BRK0,P00846,O43464,Q96F07,Q9H6K4,Q96CU9,Q15392,Q96RR1,O43681,Q8NC96,P52732 13 +Hyporeflexia 0.3496688095618072 1.4883818253232797 0.1366502268584579 1.0 0.3605273894401948 115 Q9Y3B2,Q99720,Q9BQP7,P03886,Q8NC96,O75648,Q13045,P41440,Q9NR77,Q96AX1,O43681,O95831,O95817,Q92974,P54802,P50570,P00846,Q96F07,Q96RR1,Q96RL7,P83436,O95319,O75787,Q8IY17,Q71SY5,Q10713,P07196 27 +Abnormality of hepatobiliary system physiology 0.3838905407256011 1.4839151643436357 0.137831428337233 1.0 0.3631773603604727 76 P22830,P00846,O43819,P50416,Q16625,Q9Y619,O15118,P23786,Q5XKP0,O43772,Q9NSD9,P03886,P55263 13 +Positive romberg sign 0.6219872346411023 1.4806862320550476 0.1386902044820415 1.0 0.3644237971598886 9 P41440,Q96RR1,Q9H6K4 3 +Decreased ldl cholesterol concentration 0.6095753484585931 1.4755863687237445 0.1400549666966746 1.0 0.3665216632789925 5 P04114 1 +Head titubation 0.6366240666661231 1.4750179422716116 0.1402077197170543 1.0 0.3667095671583466 7 Q96RL7,Q99720 2 +Soft skin 0.6197862415776506 1.46984230447844 0.1416044685775865 1.0 0.3697223300613643 9 Q13126 1 +Abnormality of the antitragus 0.5740541919352878 1.4667682672169426 0.1424391047780031 1.0 0.3708864744509875 4 Q8IY17 1 +Mania 0.5726796448115744 1.4666716403240816 0.142465401177614 1.0 0.3708864744509875 13 Q96RR1,Q92766,P03886,P21964 4 +Spastic paraparesis 0.504754426761817 1.464105431451116 0.1431651434771286 1.0 0.3720815260765305 20 O75787,Q6W2J9,Q6DKK2,Q9Y619,Q9H6K4,Q5XKP0,Q9Y3Z3,Q8N0X7 8 +Abnormality of neutrophil physiology 0.5720297831013257 1.4564116781599667 0.1452788491612207 1.0 0.3771422273354325 4 Q9Y3A5,Q7Z2Z2,P61011 3 +Tetany 0.6051013706229399 1.453798985283611 0.1460020449049754 1.0 0.3783893973435565 5 Q92766 1 +Respiratory distress 0.4089388959666353 1.452092505491153 0.1464758855339707 1.0 0.3787304574594106 48 P49748,O75648,P00846,O43819,P51970,Q9Y619,Q96AX1,P23786,P03886,O95831,O60762 11 +Mental deterioration 0.3717714999517486 1.4516425536737918 0.1466010200765972 1.0 0.37883777578265 91 Q96RL7,Q8NHS3,Q8IY17,P54802,P00846,O43819,Q96F07,O75503,O15118,Q5XKP0,Q9Y487,Q96RR1,P03886,Q10713,Q14108,Q8NC96,Q03164,P50897 18 +Contractures of the joints of the upper limbs 0.3813437409686251 1.444866790790837 0.1484953059353386 1.0 0.3826414879903778 73 Q9Y2B2,Q71SY5,Q9Y2D4,Q99720,Q9NR77,Q9Y619,Q8IZA0,Q15392,P23786,Q9UP83,P57740,Q99567,Q96AY3,P42892,Q8WXH0,P07196 16 +Respiratory arrest 0.6219871768332045 1.4414810506126017 0.1494488269911356 1.0 0.3848795828708609 8 P23786,O43772 2 +Abnormal auditory evoked potentials 0.6293072248874549 1.4403571350639588 0.1497663844202001 1.0 0.3849292371070687 7 Q13614,P07196 2 +Eeg with multifocal slow activity 0.6210440044813816 1.43691893466962 0.1507410290758699 1.0 0.3868877403477002 8 Q8NC96,Q96F07 2 +Easy fatigability 0.4902883359095618 1.434109760049434 0.1515409431104326 1.0 0.3883747215432013 21 P50570,Q9BQP7,Q9NWM8,P61978,Q96RR1 5 +Abnormal circulating sulfur amino acid concentration 0.6203179890846046 1.433406420619992 0.1517417245886343 1.0 0.3884597768035016 8 P41440 1 +Pancreatic hypoplasia 0.600388601036268 1.4308184858548847 0.1524822436317143 1.0 0.3896461009060284 5 P40763,O00330,Q9Y3A5,P61011 4 +Memory impairment 0.4620915392149257 1.4307430463750157 0.1525038712817634 1.0 0.3896461009060284 30 Q9BRK0,Q8NBM4,Q9NZ08,Q96RR1,P03886,O43681,Q12824 7 +Supranuclear gaze palsy 0.4882467650242109 1.420390299090056 0.1554940854426352 1.0 0.3957237118287289 21 O15118,Q96RL7,Q99720,Q96RR1 4 +Recurrent fractures 0.4658016447730689 1.4195394928645304 0.1557417915334473 1.0 0.3959092680395716 28 P48735,Q13126,Q32P28,Q9UNW1,Q96AY3 5 +Microscopic hematuria 0.5265068801438053 1.4177860661595962 0.156253233440631 1.0 0.3960980120235358 3 Q03252 1 +Wormian bones 0.5160529282002339 1.4162021568691503 0.1567163245898521 1.0 0.3968278090508834 18 Q32P28,Q96AY3,Q9Y487,O95831 4 +Low levels of vitamin d 0.6166648316544276 1.4157220643986883 0.1568568956377254 1.0 0.3969618643792716 8 Q9NSD9 1 +Focal segmental glomerulosclerosis 0.4872242631375071 1.4135154674178114 0.1575042167650266 1.0 0.3979331299194483 21 Q14C86,P00403,Q96AX1,Q8N1F7,P57740,O95470,P03886,Q14108 8 +Abnormal circulating long chain fatty acid concentration 0.5965455010513676 1.4120569022588303 0.1579332072749331 1.0 0.3985723838191904 5 P23786,O96011 2 +Babinski sign 0.3693331958101679 1.4100454541223957 0.1585262617796081 1.0 0.3995151822185959 90 Q9BRK0,Q8IY17,P00846,P41440,Q99720,Q9NR77,Q6DKK2,Q9H6K4,O95831 9 +Ventricular hypertrophy 0.4401446184390957 1.4075476234401114 0.1592650660042673 1.0 0.4008170827774062 36 P23786,O43772 2 +Hepatic failure 0.407995054758841 1.401987829516263 0.160918881039964 1.0 0.4043053417143854 46 P22830,P00846,P50416,Q9Y619,O15118,P23786,O43772,P03886 8 +Increased serum lactate 0.343680964803036 1.4007497129732986 0.1612889310206011 1.0 0.4050104531725739 115 Q9P0J0,Q9BWD1,Q7KZN9,P00846,O43819,Q70HW3,O43464,Q96CU9,Q5XKP0,Q9Y584,Q9Y375,P03886,Q96RR1,P13073,O95831,Q86VD7 16 +Chronic pulmonary obstruction 0.6208334110548827 1.4001316268155122 0.1614739058002094 1.0 0.4050259098975354 7 Q92766,P09601 2 +Abnormality of endocrine pancreas physiology 0.5603083421159688 1.3963254904589186 0.1626165011160214 1.0 0.407440680340474 4 P40763,Q14739 2 +Slowly progressive 0.3760005681778543 1.3942747200268932 0.1632346618082611 1.0 0.4083119922647284 59 Q9BRK0,P50570,P41440,Q99720,Q9NR77,O14773,O95831 7 +Atrophic scars 0.6257380672386228 1.390385085176547 0.1644119730674247 1.0 0.4103505443501014 6 Q9NWM8 1 +Secondary growth hormone deficiency 0.5590787662722007 1.3900113149154012 0.1645254414770329 1.0 0.4104076265919379 4 Q12824,Q99496 2 +Optic neuropathy 0.465838871276262 1.3864428283959245 0.1656117263486543 1.0 0.4127865519203525 26 Q9P0J0,P00846,Q96CU9,Q9Y375,P03886,P04114 6 +Abnormal peripheral myelination 0.4559631052867836 1.3844886477538578 0.1662088817681217 1.0 0.4134885179193792 30 Q13614,Q96RL7,P20700,P50570,P00846,Q9NR77,P03886,P07196 8 +Functional intestinal obstruction 0.5578540145745121 1.383719958825816 0.1664442197452513 1.0 0.4134885179193792 4 P42771,P38398 2 +Extrahepatic cholestasis 0.5578540145745121 1.383719958825816 0.1664442197452513 1.0 0.4134885179193792 4 P42771,P38398 2 +Peritoneal abscess 0.5578540145745121 1.383719958825816 0.1664442197452513 1.0 0.4134885179193792 4 P42771,P38398 2 +Aplasia hypoplasia involving the femoral head and neck 0.5942244319364021 1.383568102349623 0.1664907409900546 1.0 0.4134885179193792 10 Q96HY6,O95831,Q99575,Q9NR45 4 +Peripheral axonal degeneration 0.3758847193350373 1.3777133509801065 0.1682918076261981 1.0 0.4172158808279845 66 Q8IY17,P50570,P00846,P41440,Q6DKK2,Q96RR1,P03886,Q9BQT8,O95831 9 +Hypoglycemic seizures 0.608461915118752 1.3759549974770957 0.1688355664073926 1.0 0.417937221762562 8 P31751,Q13423 2 +Respiratory failure 0.3753819063960302 1.3745876927010952 0.1692593063163763 1.0 0.4184892893102841 64 O43819,O43464,Q70HW3,Q9BQP7,Q9Y619,Q15165,Q5XKP0,P23786,Q96B26,Q92804,Q9NSD9 11 +Focal t2 hyperintense basal ganglia lesion 0.4698335293651142 1.37434135818934 0.1693357322970752 1.0 0.4184892893102841 23 P03886,Q96CU9,P00846 3 +Decreased plasma carnitine 0.5541414047270905 1.3646535674865334 0.1723619598839625 1.0 0.4236569062801683 13 P23786,O43772 2 +Visual field defect 0.4111677520715842 1.3626743859312742 0.1729851538107285 1.0 0.4247277760230896 42 Q9H061,Q8NHS3,P03886,P00846 4 +Knee flexion contracture 0.457802892265905 1.3605220671197678 0.1736647746163675 1.0 0.4257042364784334 28 Q86XL3,P23786,P49902,Q96AY3,O95817,O60762 6 +Cholestatic liver disease 0.5523115957898799 1.35522618587433 0.1753455041690061 1.0 0.4286644003699935 4 Q9H267 1 +Abnormal involuntary eye movements 0.2928553900879561 1.3489857945105312 0.177341528935331 1.0 0.4309855826593614 275 Q9P0J0,Q99720,O75380,P36405,Q9BZK7,O43772,P03886,Q9NQT5,Q8NC96,Q08J23,O96000,P52732,O75648,P20700,P41440,Q9H061,Q16625,Q9NR77,Q6DKK2,Q96AX1,Q5XKP0,Q15392,O96011,Q9Y375,Q9UNW1,O14773,O95831,Q5KU26,Q92974,Q8WWY3,P00846,O75381,Q96F07,O75503,Q9NR45,Q96CU9,P49902,Q96RR1,Q96D71,O60762,O95319,Q9BXW9,Q8IY17,Q7KZN9,O43819,Q9H9P8,Q9H6K4,Q05086,Q9UQE7,Q9UEY8,Q10713,O43678,O96028,P07196,P78318 55 +Exercise intolerance 0.4395710857554697 1.3484893237798494 0.1775010517075386 1.0 0.4311419647373458 34 P23786,Q96RR1,Q9NSD9,P03886 4 +Talipes calcaneovalgus 0.6153003657092461 1.3416462335341488 0.1797107278912082 1.0 0.4351093518691466 6 Q9H267,Q9NR77,P07196 3 +Headache 0.3724928888008605 1.3412991325413384 0.1798233513413791 1.0 0.4351494559703246 65 Q8NBM4,O00429,P23786,Q9NZ08,Q9Y3Z3,P03886,Q13586,O96011,Q99496,P00846,P00403,O43791,P21912,Q9NSD9,Q96RR1,Q12824,Q14C86,O60313,Q8N1F7,P57740 20 +Phenotypic variability 0.3568042571256083 1.3400667046629269 0.1802236595377699 1.0 0.4354203614432522 99 Q9UBQ7,Q70HW3,O00429,Q6P4A7,Q9Y3Z3,P03886,Q92733,Q9BUF5,Q08426,Q9NQT5,P52732,Q9H061,Q9NR77,Q9Y375,O95470,Q8WWY3,P00846,P00403,P21912,Q12824,O60762,Q9BVA1,Q9UEY8,P57740,O14979,P07196 26 +Ventricular preexcitation 0.607648963640992 1.3373878339762473 0.1810960735819735 1.0 0.4370806123196213 7 P03886 1 +Muscle hypertrophy of the lower extremities 0.6143843585218328 1.337364087272332 0.1811038210428099 1.0 0.4370806123196213 6 Q9NR77 1 +Titubation 0.5921748846087163 1.3332693963597504 0.182443412961321 1.0 0.4387137270687813 9 Q96RL7,Q99720,Q5JRX3 3 +Pericarditis 0.5480365112029155 1.3332236383808047 0.1824584242378772 1.0 0.4387137270687813 4 Q9NZ08 1 +Central diabetes insipidus 0.4742801682303494 1.329946432851008 0.1835359212030298 1.0 0.4403808785160461 2 P35222 1 +Heinz bodies 0.4739566483338755 1.328055774789387 0.1841596820411806 1.0 0.4412164349841216 2 O14936 1 +Distal upper limb amyotrophy 0.5713815600398995 1.325829510092715 0.1848961758667704 1.0 0.4424266508397049 11 Q9NR77,Q9BQT8 2 +Long toe 0.5905053648288904 1.324984458781551 0.1851763059789126 1.0 0.4424266508397049 9 P23786,Q8WXI9 2 +Abnormal chorioretinal morphology 0.461026027853927 1.3244009173859652 0.1853699300869227 1.0 0.4424266508397049 24 Q8IY17,Q6W2J9,O75381,Q9Y619,Q96AX1,O60826,Q5XKP0,O96011,Q10713,P04439,P52732,O43505 12 +Abnormal choroid morphology 0.461026027853927 1.3244009173859652 0.1853699300869227 1.0 0.4424266508397049 24 Q8IY17,Q6W2J9,O75381,Q9Y619,Q96AX1,O60826,Q5XKP0,O96011,Q10713,P04439,P52732,O43505 12 +Vertebral compression fracture 0.525848689422113 1.3214762023206883 0.186342632352944 1.0 0.4442800655572823 15 Q96HY6,Q96AY3,Q32P28,Q14108 4 +Sloping forehead 0.4260445886496132 1.3208561213080603 0.1865493427531261 1.0 0.4445389388067656 37 Q9BXW9,Q86XL3,Q16625,Q9BSJ2,P23786,P57740,P38398,Q9H267,Q08J23,O60566,P52732 11 +Absent thumbnail 0.5084142394822051 1.3188732818498032 0.1872114797774475 1.0 0.4456868905275667 3 O14936,Q9H936 2 +Recurrent sinopulmonary infections 0.6032452226056344 1.3163943048134543 0.1880417329636636 1.0 0.4466891422595822 7 Q9Y487 1 +Stroke like episode 0.6032442368640417 1.3163896037861793 0.1880433099975769 1.0 0.4466891422595822 7 P51970,P00403,P03886 3 +Gastrointestinal inflammation 0.4999238075700638 1.315561039234913 0.1883214175427783 1.0 0.446881100821784 18 P49748,P08183 2 +Fever 0.3698110706043274 1.31517797378044 0.1884500959155155 1.0 0.4469523217263274 74 P00846,Q14C86,Q9NR77,P61978,Q9BZK7,P23786,Q9NZ08,P28070,P03886,Q9Y2V7 10 +Abnormal pyramidal sign 0.3262326964867559 1.314596628891606 0.1886455036932914 1.0 0.4471816492572529 123 Q9P0J0,Q8NBM4,Q99720,Q9NZ08,Q9Y3Z3,Q8TD30,P20700,P41440,Q6DKK2,Q9NR77,O43681,O14773,Q8N0X7,O95831,Q9BRK0,P00846,P49902,O75787,Q8IY17,Q9H9P8,P51572,Q9Y619,Q9H6K4,Q9UEY8,P07196 25 +Abnormal circulating dicarboxylic acid concentration 0.4023430927945068 1.3142257262572925 0.1887702534602573 1.0 0.4472433306354423 44 P41440,P23786,P48735,Q9NSD9 4 +Muscle fiber tubular inclusions 0.5071197411003281 1.3117803191240296 0.1895942672489894 1.0 0.4489608105791542 3 Q9H553,Q13586 2 +Fluctuations in consciousness 0.6085328094555734 1.3099929083760522 0.1901982346520623 1.0 0.449920628184774 6 P03886 1 +Biconcave vertebral bodies 0.5754455856979998 1.308748993152698 0.1906193899618922 1.0 0.450681543072741 5 Q96AY3 1 +Neuropathic arthropathy 0.5064724919093899 1.3082331688911275 0.1907942350427847 1.0 0.4508596164547808 3 O15269,O15270 2 +Hemiparesis 0.4984891521621969 1.3065901003219167 0.191351960588213 1.0 0.4519418047260714 18 Q8NBM4,P00403,O60313,O43791,O00429,Q9BVA1,Q9NZ08,P03886,Q12824,Q99496 10 +Thin ribs 0.5435404758735722 1.306105161529772 0.1915167979446299 1.0 0.4520954115107731 13 P50570,Q32P28,Q9Y2D4,Q9Y619,O95831 5 +Abnormality of the optic nerve 0.3065566170406525 1.303591794131111 0.1923728000051867 1.0 0.4536433024588735 242 Q9P0J0,Q8NBM4,O75380,P61978,P36405,Q9NZ08,P03886,P50897,Q8NC96,P04114,Q92734,O96000,P52732,Q8NHS3,Q8WXI9,O75648,P41440,Q9H061,Q6P4Q7,Q96TA2,Q96AX1,Q5XKP0,O96011,Q96PU5,Q9UNW1,O43676,Q9Y375,O43681,O95831,Q5KU26,Q92974,Q8WWY3,Q9BUK6,P00846,Q6W2J9,Q96F07,O75381,P00403,O43791,O94979,Q96CU9,P49902,Q96RR1,Q9Y2V7,P38435,Q12824,O60762,O95319,Q8IY17,Q92766,Q7KZN9,O43819,Q9H9P8,P51572,Q9BSJ2,Q9H6K4,Q10713,P21964,O43678,O96028,P04439,P07196,P78318 63 +Dilated cardiomyopathy 0.4163436146600045 1.3011980231708389 0.1931906817612669 1.0 0.4550038273939332 39 P49748,Q96RL7,P00846,O43819,Q9BQP7,P23786,Q96RR1,P03886,O95817 9 +Microcytic anemia 0.5764200618104868 1.2933596614995593 0.1958866948294559 1.0 0.460730388150278 10 P22830 1 +Abnormal circulating fatty acid anion concentration 0.5208428533873959 1.2922946817976158 0.1962551130088163 1.0 0.461357375158245 15 P23786,O43772 2 +Xerostomia 0.5405852597282537 1.2897623692825846 0.1971331771989311 1.0 0.4627887645236894 13 P55011,P35637,Q15165,Q14203,Q92804,P43243,Q14739,P50995 8 +Median cleft lip 0.4671627305079249 1.2883219896003215 0.1976339016041839 1.0 0.4627887645236894 2 Q14683 1 +Cyclopia 0.4671627305079249 1.2883219896003215 0.1976339016041839 1.0 0.4627887645236894 2 Q14683 1 +Abnormal dura mater morphology 0.4671627305079249 1.2883219896003215 0.1976339016041839 1.0 0.4627887645236894 2 Q14683 1 +Panhypopituitarism 0.4671627305079249 1.2883219896003215 0.1976339016041839 1.0 0.4627887645236894 2 Q14683 1 +Median cleft palate 0.4671627305079235 1.288321989600314 0.1976339016041866 1.0 0.4627887645236894 2 Q14739 1 +Constitutional symptom 0.3085252411045974 1.2881858009986675 0.1976812934554832 1.0 0.4627887645236894 235 Q70HW3,Q99720,Q4J6C6,Q15165,P23786,Q9BZK7,Q9NZ08,Q14108,P04114,P42892,P52732,P49748,P20700,Q9NR77,P28070,O96011,Q9UNW1,O43681,P04899,Q8WXH0,Q96HY6,Q9BRK0,P50570,P00846,Q92804,Q9UP83,Q96RR1,Q12824,Q03252,P48735,Q92766,Q13423,P50416,Q14C86,Q9H6K4,P57740,Q9NUQ7,Q15800,P07196 39 +Kyphoscoliosis 0.3891952463209945 1.285213154555874 0.1987178080464258 1.0 0.4644951859908715 49 Q9Y2D4,Q9NR77,Q9NWM8,Q8N0X7,Q9Y487,P57740,Q9HC07,Q96AY3,Q8NCH0,Q99575,Q5KU26 11 +Abnormal corpus striatum morphology 0.5115257156005075 1.283744584817753 0.1992313388223885 1.0 0.4654553712560186 16 Q96RL7,O95831,P00846 3 +Neoplasm of the adrenal cortex 0.5699688110174703 1.2818661233856268 0.1998896135001411 1.0 0.4665120809663262 5 P48735,P42771 2 +Abnormal nephron morphology 0.3787821566590815 1.2772577624991657 0.2015112601216464 1.0 0.4688474619163114 53 Q8NBM4,P00846,O43819,Q14C86,P00403,Q96AX1,Q8N1F7,P23786,P21912,Q9NZ08,O95470,P03886,Q14108,P57740,Q03252 15 +Increased csf lactate 0.3705598971591348 1.276486553887784 0.2017835769825917 1.0 0.4691018157651579 56 Q9P0J0,Q7KZN9,P00846,O43464,O43819,Q96CU9,Q9Y375,P03886,P13073,O96000,O95831 11 +Abnormality of circulating enzyme level 0.3547227592952405 1.2737084453692882 0.2027667622933751 1.0 0.4695978697285221 95 Q86U42,Q9BQP7,Q5JRX3,Q9NWM8,P23786,P50402,O43772,Q9HC07,Q08J23,Q92734,O14653,P49748,O75648,Q16836,O95831,Q8WXH0,O95817,Q9BUK6,P50570,Q9Y584,Q96RR1,Q9Y2V7,O60762,Q86VD7,Q96RL7,P83436,P50416,O14979,P07196 29 +Aplasia hypoplasia involving the skeletal musculature 0.586102197920569 1.2672230907638578 0.2050755315350931 1.0 0.4739755907418225 8 Q9NR77 1 +Symptomatic seizures 0.5780404535802377 1.263056386550997 0.2065689162572566 1.0 0.4758783433639434 9 P31751,Q13423 2 +Gait disturbance 0.2817854055423363 1.2628748756476758 0.2066341504187365 1.0 0.4758783433639434 305 Q86U42,Q99720,Q5JRX3,P61978,Q4J6C6,O15118,Q9NZ08,Q8TD30,P03886,Q14108,Q8NC96,Q96AY3,Q03164,O14653,P49366,O75648,Q13045,P20700,P41440,Q9NR77,Q96AX1,Q5XKP0,O43681,O14773,Q8N0X7,O95831,Q8WXH0,Q9Y2B2,Q9BRK0,P50570,P00846,O43464,Q9Y5P4,Q96F07,O75503,Q96CU9,P49902,Q96RR1,Q96D71,Q12824,Q03252,Q96RL7,O95319,O75844,Q8IY17,Q71SY5,O43819,Q9Y619,Q9H6K4,Q05086,Q10713,Q9BQT8,Q9NUQ7,P07196 54 +Abnormality of pulmonary circulation 0.4370524996319913 1.260628953160208 0.207442562110578 1.0 0.4770125920613798 31 O75844,Q8NBM4,Q71SY5,P51970,Q96AX1,Q8IZA0,Q9NZ08,P03886,Q14108,Q69YQ0,O96000 11 +Bruxism 0.5846365433278685 1.260082714876832 0.2076395250403888 1.0 0.4770669918796441 8 Q96RL7,Q9Y5P4 2 +Hyperactive deep tendon reflexes 0.5767151126596299 1.2564655771322182 0.2089472187869026 1.0 0.4794247581969687 9 O00429,Q9NR77,O75787,P21912 4 +Tetraplegia 0.546518459163364 1.2562627353371345 0.2090207279114819 1.0 0.4794247581969687 12 Q13423,P51970,P51572,O43681,O95831 5 +Thick upper lip vermilion 0.5834724278158008 1.254410523294561 0.2096928295693723 1.0 0.4798343569189695 8 Q9UNW1 1 +Abnormal brain positron emission tomography 0.5322127480843504 1.2516353247317316 0.2107027766207017 1.0 0.4815759728010992 4 Q12824,Q99496 2 +Hyperconvex nail 0.5825255884688164 1.2497964894681557 0.2113738988148816 1.0 0.4826522790794599 8 P42892 1 +Dysphagia 0.3225608148476243 1.248927597236188 0.211691556712817 1.0 0.4831046609113658 129 Q86U42,Q99720,P29372,Q9BQP7,O15118,P03886,Q14108,Q9BUF5,Q69YQ0,Q92734,Q03164,P20700,Q9NR77,Q8N0X7,P18887,P00846,Q8NFF5,Q8IZA0,O94979,P21912,Q96RR1,Q9BPU6,Q96D71,Q96RL7,P48735,O43819,P35670,Q05086,Q9UEY8 29 +Airway obstruction 0.5132721522569986 1.2481151267365442 0.2119888994505239 1.0 0.4832578546952813 15 Q96HY6,O75844,Q92766,P09601,Q96AX1 5 +Hemiplegia hemiparesis 0.429519048068852 1.2448434817855647 0.2131892894071563 1.0 0.4843267206692167 33 Q8IY17,Q8NBM4,P50416,P00403,O60313,O43791,O00429,Q9BVA1,P57740,Q9NZ08,Q9Y3Z3,P03886,Q12824,Q99496 14 +Contractures of the joints of the lower limbs 0.3611078559733536 1.2381098768399723 0.2156753221171006 1.0 0.4882604743580538 58 O00459,Q86XL3,Q5JTV8,Q6W2J9,Q99720,Q8IZA0,P23786,P50402,P21912,P49902,Q96AY3,Q08J23,Q8WXH0,O95817,O60762 15 +Abnormal brain lactate level by mrs 0.5723289286908183 1.2346468183730857 0.2169619765039705 1.0 0.4904380007799334 9 P21912,P00403,P03886,O43819 4 +Prenatal maternal abnormality 0.5182280301393452 1.2342210308225596 0.2171205527632007 1.0 0.4905002512785494 14 O43772,P49366 2 +Mild microcephaly 0.5858690364176298 1.233425432510205 0.2174170812241036 1.0 0.4906943886666914 7 Q05086 1 +Abnormal brainstem mri signal intensity 0.4496663662093826 1.2329079040621382 0.2176101261875542 1.0 0.4906943886666914 23 O95831,Q9Y375,P03886,Q96CU9 4 +Limb joint contracture 0.3444350613083907 1.2323090891877602 0.2178336458297387 1.0 0.4906943886666914 104 Q99720,P23786,Q96AY3,Q08J23,P42892,O00459,Q9Y2D4,Q9NR77,Q15392,Q8WXH0,O95817,Q9Y2B2,Q86XL3,Q8IZA0,Q9UP83,P49902,Q99567,O60762,Q71SY5,Q9Y619,P57740,P07196 22 +Parkinsonism 0.4382118692975693 1.2320082558718382 0.2179460001549817 1.0 0.4907034695338307 29 Q96RL7,Q99720,Q96RR1,P61457 4 +Prenatal movement abnormality 0.366101908412963 1.2297407369999371 0.2187942067645232 1.0 0.4918797799718561 56 Q13045,P50570,Q7KZN9,Q70HW3,Q4J6C6,Q8NC96 6 +Neonatal insulin dependent diabetes mellitus 0.4919093851132736 1.2283253048341896 0.2193248753999244 1.0 0.4925838798025095 3 P40763,O00330 2 +Abnormal blood gas level 0.4919093851132732 1.2283253048341871 0.2193248753999253 1.0 0.4925838798025095 3 P06753,Q9Y3E5 2 +Long palm 0.4568100938207855 1.2276868848636575 0.2195645316246004 1.0 0.4928777642514568 2 Q9BZI7 1 +Abnormal left atrium morphology 0.4906148867313966 1.22121545115103 0.2220044555605955 1.0 0.4971231753284715 3 Q14315,O95235 2 +Left atrial enlargement 0.4906148867313966 1.22121545115103 0.2220044555605955 1.0 0.4971231753284715 3 Q14315,O95235 2 +Fulminant hepatic failure 0.4903333063550097 1.219668805820834 0.2225904514430217 1.0 0.4979430839688337 3 Q16836 1 +Macroscopic hematuria 0.4551924943383996 1.2182057193977411 0.2231458067698404 1.0 0.4984222532237579 2 P07741 1 +Uric acid nephrolithiasis 0.4551924943383996 1.2182057193977411 0.2231458067698404 1.0 0.4984222532237579 2 P07741 1 +Dyschromatopsia 0.5826306179033551 1.2179453065923345 0.2232447575697582 1.0 0.4984222532237579 7 Q9H061 1 +Abnormal eating behavior 0.458067876505067 1.2166985206418253 0.2237189421412666 1.0 0.4989044695657325 21 Q05086,Q4J6C6 2 +Tremor 0.3205035642806972 1.2145902639814272 0.2245224040273774 1.0 0.5000425222438643 163 Q99720,Q5JRX3,P61457,Q6P4A7,Q8TD30,P03886,Q14108,Q8NC96,O14653,P20700,P41440,Q6DKK2,Q9NR77,O14773,O95831,Q9BRK0,P00846,O43464,Q96F07,O75503,Q96RR1,O60762,Q96RL7,Q8IY17,Q9H6K4,Q05086,Q10713,P07196 28 +Mixed hearing impairment 0.5556731104366432 1.2116090136584778 0.225662082566179 1.0 0.5020870501104081 5 Q9NWM8 1 +Cortical dysplasia 0.437631904362878 1.2111307063945491 0.2258453146414851 1.0 0.5021699347004978 28 Q9UBB6,P07437,Q96PU5,Q08J23,Q9NUQ7 5 +Irregular vertebral endplates 0.5555310870330709 1.2109105853997724 0.2259296752456501 1.0 0.5021699347004978 5 Q9NR45 1 +Hyperthyroidism 0.567505608472235 1.2106439361582382 0.2260318977603344 1.0 0.5021699347004978 9 Q96RR1,Q92766,Q9BUK6,P21964 4 +Incoordination 0.3608224370481447 1.20816466496703 0.2269839303872711 1.0 0.5032977017397643 68 P00846,O43819,Q6DKK2,Q9NR77,Q9Y619,O75503,Q05086,Q96RR1,O14773 9 +Atrophy degeneration involving the spinal cord 0.57369335921327 1.2067375239351907 0.2275332431952939 1.0 0.5036418438229426 8 Q96RR1,Q8IY17,P07196 3 +Distal joint laxity 0.4870550161812348 1.2016596910596813 0.2294954044741661 1.0 0.5071288693990111 3 O75340,Q9H553 2 +Abnormal renal vascular morphology 0.5222993246205246 1.2004389131375175 0.2299689237104045 1.0 0.5079274619249793 4 P04114 1 +Abnormal nasal mucosa morphology 0.5527407179322209 1.19718728143566 0.2312335660557973 1.0 0.5101735951373524 5 Q03518,Q13432 2 +Fatigable weakness of respiratory muscles 0.5354436340843206 1.1967221295115311 0.2314148786240941 1.0 0.5101735951373524 12 P35637,Q15165,Q14203,Q92804,Q9Y281,P43243,P50995 7 +Arterial thrombosis 0.5526349406120055 1.1966670214406925 0.2314363660060174 1.0 0.5101735951373524 5 Q9NZ08 1 +Abnormal full field electroretinogram 0.5778723467287402 1.1951942813971712 0.2320111323182314 1.0 0.5109433298014529 7 P00846 1 +Abnormal light and dark adapted electroretinogram 0.5778723467287402 1.1951942813971712 0.2320111323182314 1.0 0.5109433298014529 7 P00846 1 +Lower limb spasticity 0.3520463155676829 1.192244928227452 0.2331652214885415 1.0 0.5122397930858842 90 Q9BRK0,Q8IY17,Q7KZN9,P00846,Q99720,Q6DKK2,Q9Y619,Q9H6K4,Q96CU9,O95831 10 +Caesarian section 0.5205226422508196 1.191259834508081 0.2335515965572636 1.0 0.5127233634665026 4 P33991,O60313 2 +Abnormality of the alveolar ridges 0.5514888869182252 1.191030074836637 0.2336417785123534 1.0 0.5127233634665026 5 Q15392,P98175 2 +Bifid scrotum 0.582265833715194 1.1868742138886297 0.2352772398998932 1.0 0.5158789432461357 6 Q69YQ0,O60566,Q9UBM7,O60315 4 +Neonatal hypoglycemia 0.5096545189809136 1.1852144058492002 0.2359326855442303 1.0 0.516815795703754 14 O43772 1 +Abnormal consumption behavior 0.4413592769202074 1.1848647315220349 0.2360709338640647 1.0 0.5168631232762292 24 Q05086,Q4J6C6 2 +Retinal vascular tortuosity 0.5088625229926451 1.1806861200452916 0.2377274374250257 1.0 0.5192407384452106 14 P03886 1 +Aganglionic megacolon 0.4523420480820829 1.1779337109018828 0.2388230344167843 1.0 0.5208802820934199 21 Q9Y2B2,Q9BXW9,Q92766,P36405,P38398,Q10713,P21964,P42892 8 +Wide intermamillary distance 0.4520851660255379 1.1761942629633677 0.2395172565225527 1.0 0.5218918576465434 21 Q9BZK7,Q9Y5P4,P61978,P23786 4 +Pigmentary retinopathy 0.3818431406585367 1.1754994931404357 0.2397949398391459 1.0 0.5222457103227552 47 Q8NHS3,Q8IY17,P00846,Q96CU9,P03886 5 +Myoglobinuria 0.5526296049426639 1.172470105419949 0.2410083675385284 1.0 0.5236659779716292 10 P23786 1 +Prominent nasal bridge 0.3831396526228329 1.170117529181897 0.2419536751677475 1.0 0.5246769499808026 46 Q9Y2B2,P42892,Q92766,P20700,P78318,Q6W2J9,Q9UQE7,P36405,P38398,P13073,Q10713,Q69YQ0,P21964,Q08J23,P49366 15 +Horizontal nystagmus 0.4375504837077302 1.169078340724404 0.2423720694962168 1.0 0.5253327630707474 25 Q9H061,O95831,P00846 3 +Small basal ganglia 0.5656978713267035 1.167739609012312 0.2429118145306406 1.0 0.5256854775775777 8 Q96RL7,P00846 2 +Cavernous hemangioma 0.5152583831514004 1.1640596168392905 0.2443998526020072 1.0 0.5272053963271871 4 P50570 1 +Limb tremor 0.576984244603183 1.1620925320616706 0.2451978805697776 1.0 0.5284235960899585 6 Q9NR77 1 +Genu varum 0.5392616579613988 1.1581085699246785 0.2468197331562622 1.0 0.5314132087442339 11 Q96HY6,Q9Y619 2 +Oligohydramnios 0.420999371724676 1.1566283820846317 0.2474242213029338 1.0 0.5324616258918244 32 P49366,Q9Y2B2,Q9BXW9,Q9NVI1,Q9Y5P4,P23786,P51114,Q9UP83,Q9NSD9,P38398,O60566,Q99496 12 +Motor axonal neuropathy 0.5164696000532215 1.1561901982498606 0.2476033681713332 1.0 0.5325613086824159 13 O95831 1 +Annular pancreas 0.4781766599678022 1.1528747671328747 0.2489617903161916 1.0 0.5342477073104444 3 Q9BXW9 1 +Abnormality of the musculature of the lower limbs 0.4365222934994631 1.1504993422201777 0.2499382649752666 1.0 0.5350391349948314 24 Q96RL7,P50570,P00846,Q9NR77,O14979,Q8WXH0,P07196 7 +Abnormal circulating metabolite concentration 0.2809097549208589 1.1503747989241415 0.2499895351572687 1.0 0.5350391349948314 337 Q9P0J0,Q9BWD1,Q70HW3,Q9BQP7,Q9NWM8,P61457,Q4J6C6,P23786,O43772,Q9HC07,P03886,P04114,Q08J23,O14653,P49748,Q13045,P41440,Q5XKP0,P28070,Q9Y487,Q9Y375,O95831,P22830,P00846,P50570,Q96CU9,Q9Y584,Q9NSD9,Q96RR1,Q9Y2V7,Q86VD7,Q96RL7,P48735,Q13423,O43819,P50416,Q14C86,P31751,Q9Y619,P55263 40 +Abnormality of vitamin d metabolism 0.5553393826246218 1.1500764764340246 0.2501123741164699 1.0 0.5350391349948314 9 Q9NSD9 1 +Abnormality of circulating leptin level 0.5125310499564766 1.1499672256058888 0.2501573704015569 1.0 0.5350391349948314 4 P31751 1 +Abnormal macroscopic urine appearance 0.4813650444673514 1.1493122092696444 0.250427265427152 1.0 0.535363620757432 17 Q14C86,P57740,P23786 3 +Tented upper lip vermilion 0.4345023122809499 1.1471909673805 0.2513027038757256 1.0 0.5359704560061379 25 Q71SY5,Q13045,Q96F07,Q4J6C6,O60762 5 +Functional abnormality of the gastrointestinal tract 0.2869438387135137 1.1451833506712208 0.2521332137172023 1.0 0.5368284136903134 268 Q8NBM4,Q86U42,Q99720,P29372,Q9BQP7,P61978,O15118,Q9NZ08,P03886,Q14108,Q9BUF5,Q69YQ0,Q8NC96,P42892,Q92734,Q03164,P49748,Q13045,P20700,Q9NR77,Q96AX1,Q96PU5,P38398,Q8N0X7,P18887,Q96J02,P00846,Q8NFF5,Q96F07,P00403,Q8IZA0,O43791,O94979,P51571,P21912,Q9Y584,Q9NSD9,Q96RR1,Q9Y2V7,Q96D71,P08183,Q96RL7,P83436,O95319,P48735,Q92766,O43819,Q9Y619,Q05086,Q9UQE7,Q9UEY8,P21964,O96028 53 +Decreased activity of mitochondrial complex iv 0.472436775957309 1.143375678538269 0.2528826460780871 1.0 0.5378208388421288 18 Q70HW3 1 +Muscle fiber inclusion bodies 0.5538102799730857 1.1424637778318407 0.2532612940786258 1.0 0.5383733750240146 9 Q13586,Q14315,Q9Y281,O43676,P09651,P07196 6 +Agitation 0.4260932736392659 1.1410168792650228 0.2538628989140092 1.0 0.5392259595386001 29 O43464,P48449,Q15165,Q92804,P42892 5 +Abnormal biliary tract morphology 0.4468771359650487 1.1409266810934426 0.2539004352529435 1.0 0.5392259595386001 21 Q96J02,P09601,Q5XKP0,Q9NSD9,O43681,Q14108,Q10713 7 +Abnormal csf metabolite level 0.3534214137682673 1.1385750710661684 0.2548804309462176 1.0 0.540800164958485 62 Q9P0J0,Q7KZN9,P00846,O43464,O43819,Q96CU9,Q9Y375,P03886,P13073,O96000,O95831 11 +Abnormality of chromosome stability 0.4937857322685763 1.1342617968661564 0.2566847490447055 1.0 0.5432741058297377 15 Q969G3,Q9BXW9,Q9NVI1,Q06787,P38398,P13073,Q12824,P33991,Q99496 9 +Limb dystonia 0.4706473398967958 1.1321565513248038 0.2575686230899592 1.0 0.5441441370640275 18 Q5BJH7,Q99720 2 +Decreased methylcobalamin 0.4737864077669954 1.1287518466812805 0.2590025311523458 1.0 0.5464748328458904 3 O14678,Q99707 2 +Unilateral ptosis 0.4396635393076663 1.1271528395667632 0.2596778659702121 1.0 0.5476220085055856 2 Q14683 1 +Anal stenosis 0.5080521677357562 1.1268264677022508 0.2598158576274896 1.0 0.5476220085055856 4 Q08J23 1 +Abnormal head movements 0.5332347406524242 1.1266064749906286 0.2599089002841079 1.0 0.5476220085055856 11 Q96RL7,P20700,P35637,Q99720,P11166,Q06787 6 +Hiatus hernia 0.5564057852430335 1.1224164380355115 0.2616854184936792 1.0 0.5508526699704307 8 Q8NCH0,P57740 2 +Ovoid vertebral bodies 0.5682694692168634 1.1212046577446029 0.2622007575689293 1.0 0.5511832602853279 6 Q99575 1 +Secondary microcephaly 0.3530329550405697 1.1189613953954556 0.2631566087176167 1.0 0.5524093778919387 71 Q9NQT5,P83436,O43464,Q9Y5P4,Q9BSJ2,Q96CU9,Q5XKP0,Q05086,Q9Y487,Q8TD30,Q9HC07,P50897,Q9Y2V7,Q5KU26,O60762 15 +Abnormality of tibia morphology 0.5314795946353779 1.1174339053426323 0.2638088449774591 1.0 0.5535220323056461 11 O95831 1 +Recurrent abscess formation 0.437398900032349 1.1138764820844231 0.265332179961216 1.0 0.5554319663698284 2 O00203 1 +Heart block 0.4507791605900309 1.1092511778622725 0.2673218402795356 1.0 0.5572793080838917 20 P23786,O43772 2 +Fatigable weakness of bulbar muscles 0.518349516833782 1.104778688673662 0.2692554970754885 1.0 0.5597647552785513 12 P35637,Q15165,Q14203,Q92804,P43243,P50995 6 +Hydroxyprolinuria 0.4357813005499809 1.104394929314259 0.2694218594398898 1.0 0.5598536803957344 2 P30038 1 +Fatigable weakness of swallowing muscles 0.528476162614344 1.101740178518411 0.2705746441298124 1.0 0.5607349991141478 11 P35637,Q15165,Q14203,Q92804,P43243,P50995 6 +Progressive hearing impairment 0.5062402133979187 1.099504741803204 0.2715479668257696 1.0 0.5609267166989222 13 O96011,Q96RR1,P03886 3 +Dicarboxylic aciduria 0.4276441262273832 1.0979495511920316 0.2722265190141759 1.0 0.5618160050725363 25 P48735,P23786,O43772 3 +Acute phase response 0.456927928490588 1.0956563116479283 0.2732292084468493 1.0 0.5631157025769915 19 P41440 1 +Speech articulation difficulties 0.4673139158576105 1.0931998227487547 0.2743060748591301 1.0 0.5642900784457809 3 P30038,P08754 2 +Optic atrophy 0.3120509180221019 1.0931851868546028 0.274312499564264 1.0 0.5642900784457809 177 Q9P0J0,P03886,P50897,Q8NC96,P52732,Q8NHS3,P41440,Q9H061,Q96TA2,Q96AX1,Q5XKP0,O96011,Q96PU5,Q9UNW1,O43681,Q5KU26,Q8WWY3,P00846,O75381,Q96F07,Q96CU9,P49902,Q96RR1,Q9Y2V7,O60762,O95319,Q8IY17,Q92766,Q7KZN9,O43819,Q9H9P8,P51572,Q9BSJ2,Q9H6K4,P21964,O43678 36 +Cystic hygroma 0.5622420677496518 1.0929360840570892 0.2744218637563036 1.0 0.5642900784457809 6 Q99567,Q96S52,P61978 3 +Abnormality of the knee 0.345166239153199 1.0884824778282074 0.2763821678142635 1.0 0.5675481505886735 88 P23786,Q96AY3,O00459,Q9Y2D4,Q9NR77,Q96PU5,Q8N0X7,O95831,O95817,Q96HY6,Q9Y2D2,Q86XL3,Q6W2J9,P21912,Q9UP83,P49902,Q9BPU6,Q9Y5S9,O60762,Q92766,Q9Y619,Q9Y4R8,P21964,Q9NUQ7 24 +Skin nodule 0.4388248544151209 1.0864095988632996 0.2772978166839697 1.0 0.5686550971382448 21 Q92990,P48735,Q8NBM4,O75874,P21912,Q9NZ08,P04114,P52732 8 +Myoclonic seizure 0.3597892322613742 1.085083811143996 0.2778845367246436 1.0 0.5692037926595461 53 Q8NHS3,P00846,Q9UBB6,Q9Y619,Q5XKP0,P03886 6 +Type i diabetes mellitus 0.524667521446081 1.0818451474045303 0.2793213417311908 1.0 0.5709953420768477 11 P03886 1 +Gastroparesis 0.5414891898434302 1.081145365054227 0.2796324565432777 1.0 0.5710450131373448 9 Q96RR1,P61978 2 +Color vision defect 0.4911335355134961 1.0793362057454217 0.2804378783623171 1.0 0.5719872080059868 14 Q9H061,Q13432,Q9H6K4 3 +Abnormal femoral neck morphology 0.3969633619474318 1.078758325090461 0.2806954774666317 1.0 0.5722549563113599 37 Q96HY6,Q9Y2D4,O75718,Q9Y619,Q99575,Q9NR45,Q9NUQ7,Q9Y487,Q96AY3,O95831 10 +Abnormal posterior segment imaging 0.4985980519525133 1.0780039995722766 0.2810319712525673 1.0 0.5726832342663652 4 Q8WWY3 1 +Broad hallux phalanx 0.4309285021028801 1.0759610409611953 0.2819446804680336 1.0 0.5741528003024543 2 Q6DKJ4 1 +Poor eye contact 0.3792119086799841 1.075822565476411 0.2820066182501017 1.0 0.5741528003024543 42 Q9P0J0,Q96CU9,Q5XKP0,Q9Y375,P03886,Q96RR1,Q5KU26 7 +Myoclonic spasms 0.5580705103995858 1.073380811675341 0.2831002902516775 1.0 0.5761205367655431 6 Q10713,P00846 2 +Dyslexia 0.5579097394528885 1.0726273490183538 0.2834383488438716 1.0 0.5765494927089082 6 Q9H6K4,Q13586 2 +Gangrene 0.5227635227321505 1.0719025708613354 0.2837637953798548 1.0 0.5769524205883045 11 Q9BZK7,Q9NZ08,Q8NBM4,P52732 4 +Juvenile aseptic necrosis 0.5574342247352744 1.0703989131777742 0.2844397882844065 1.0 0.5780052637204607 6 Q9Y619 1 +Abnormal circulating glutamine concentration 0.4296344225169818 1.068382090766788 0.2853481922146708 1.0 0.5790819086063486 2 Q9UJS0 1 +Elevated urinary dicarboxylic acid level 0.4289873827240389 1.0645932539027083 0.2870600339478726 1.0 0.5806406298324865 2 P50336 1 +Respiratory paralysis 0.4289873827240389 1.0645932539027083 0.2870600339478726 1.0 0.5806406298324865 2 P50336 1 +Porphyrinuria 0.4289873827240389 1.0645932539027083 0.2870600339478726 1.0 0.5806406298324865 2 P50336 1 +Elevated urinary delta aminolevulinic acid 0.4289873827240389 1.0645932539027083 0.2870600339478726 1.0 0.5806406298324865 2 P50336 1 +Adducted thumb 0.4214120789432745 1.0644698703204296 0.287115896429309 1.0 0.5806406298324865 26 P83436,P42892,Q71SY5,Q86XL3,Q8NCH0 5 +Hypocalcemia 0.4745650720706519 1.0629152889600595 0.287820368914895 1.0 0.5812867905414509 16 Q9NSD9,Q4J6C6 2 +Breech presentation 0.5437628029535123 1.0607925036324588 0.2887842097400825 1.0 0.5817471724964774 8 Q9Y619 1 +Left ventricular systolic dysfunction 0.5552068704821711 1.0599626537526528 0.2891615899384323 1.0 0.5819200366153259 6 P49748,Q96RR1 2 +Exercise induced myalgia 0.5302934047288892 1.0589352508810193 0.289629268873607 1.0 0.5821156668994149 10 P49748,P23786 2 +Cupped ear 0.4806001994254991 1.057249307067586 0.2903978221138763 1.0 0.5831398100188665 15 Q15392,Q9Y2B2,P42892,P78318 4 +Posterior subcapsular cataract 0.4935668317993957 1.0520451874785537 0.2927788181591881 1.0 0.5863342379580558 4 Q9H6K4 1 +Distal amyotrophy 0.3540700700062678 1.050997564313113 0.2932597085062656 1.0 0.5865194170125312 54 Q13614,Q8IY17,P50570,Q99720,Q9NR77,Q9BQT8 6 +Incomplete penetrance 0.4072001400090331 1.0491394877583695 0.2941139242837596 1.0 0.5874497694027473 32 Q8WWY3,O14979,P00846,O60313,P11166,P21912,Q06787,Q92733,P50995,P03886,Q12824,P52732 12 +Dyskinesia 0.3464272950606253 1.0460702769495651 0.2955285870201782 1.0 0.588200570826629 68 Q96RL7,Q5BJH7,Q9P0J0,P00846,O43464,O43819,Q96F07,Q9UBB6,P03886,Q8NC96,Q08J23,Q9NUQ7 12 +Hypoamylasemia 0.4920686306247857 1.044319476320991 0.2963376048518413 1.0 0.5892929543366292 4 Q9Y3A5,Q7Z2Z2,P61011 3 +Cerebral visual impairment 0.3436085364847973 1.0349651931185515 0.3006851666639483 1.0 0.595070064742867 61 Q5BJH7,P20700,Q71SY5,Q9Y5P4,Q9UBB6,Q96CU9,Q9UP83,Q96RR1,P03886,Q08J23,Q9NUQ7,O60762 12 +Abnormality of blood volume homeostasis 0.4902036301539575 1.0347055123144329 0.3008064609542886 1.0 0.595070064742867 4 P40763,Q13277 2 +Myoclonus 0.3396152837840765 1.0345071721710335 0.3008991255946818 1.0 0.595070064742867 90 P00846,Q96F07,O75503,Q96CU9,Q05086,Q96RR1,Q9UNW1,P03886,Q9Y4G8,Q8NC96,O14773,Q10713,Q14108,P50897,O14653 15 +Excessive wrinkled skin 0.5383410020743347 1.0343973440407646 0.3009504455465581 1.0 0.595070064742867 8 Q9BZK7 1 +Hypergonadotropic hypogonadism 0.4828715556871478 1.0321668632439829 0.3019939553838513 1.0 0.5957240778698831 14 Q9BQP7,Q96RR1,P48449 3 +Central primitive neuroectodermal tumor 0.4559870550161866 1.0310583415433108 0.3025134617035399 1.0 0.5957240778698831 3 P42771,Q14145 2 +Abnormality of the fetal cardiovascular system 0.4894616611099848 1.0308817623538469 0.3025962700173512 1.0 0.5957240778698831 4 Q9Y2B2 1 +Malrotation of small bowel 0.4892829989216017 1.0299611173970504 0.3030282585063637 1.0 0.5960564529022265 4 Q8NCH0 1 +Abnormal delivery 0.4383834686712511 1.0275990456008643 0.3041384733468137 1.0 0.5979714394772528 20 P50570,O75718,Q9Y619,Q9Y487,P33991 5 +Basal ganglia gliosis 0.5368761247828924 1.0272703619733488 0.3042931742014367 1.0 0.5979714394772528 8 P00846 1 +Hyperlipidemia 0.4019091436500698 1.027048083277678 0.3043978232747339 1.0 0.5979714394772528 33 O75844,Q13045,P22830,P50416,P31751,P23786,P50402,P28070,O95470,P04114,Q8WXH0 11 +Generalized myoclonic seizure 0.3772379022683347 1.0251883860134736 0.3052743071710906 1.0 0.5989582611354115 41 Q8NHS3,P03886,P00846 3 +Abnormal visual fixation 0.541217337271396 1.0200358610975178 0.3077114534324128 1.0 0.6023910475578349 7 Q5KU26 1 +Toe walking 0.4189249679971867 1.016852710558729 0.3092235024907337 1.0 0.6044507615566888 23 Q99720 1 +Cytochrome c oxidase negative muscle fibers 0.5344792711216244 1.0156138443889295 0.3098133095548401 1.0 0.6044507615566888 8 Q96RR1 1 +Chronic diarrhea 0.4586221129707737 1.0102796508733387 0.3123613276164365 1.0 0.608429329048209 17 Q96J02,Q13277,Q9Y2V7,Q93009,Q08J23,P02786,Q96A33 7 +Abnormal circulating pyruvate family amino acid concentration 0.417894215479369 1.009622335454391 0.31267626446451 1.0 0.608429329048209 23 Q5XKP0,Q9P0J0,P03886,P00846 4 +Bone pain 0.4188634380095062 1.00884281971806 0.3130500216410676 1.0 0.6088836896777374 22 Q9BZK7,P48735,Q9UNW1 3 +Tremor by anatomical site 0.4083368080734776 1.0077490911583395 0.3135749312720155 1.0 0.6093927235788204 29 Q05086,Q99720,Q9NR77 3 +External ophthalmoplegia 0.4504628031899905 1.0057543351817413 0.3145337587376222 1.0 0.6099477427574609 18 Q13586,P50570,Q8N183,Q9BQP7,P00403,P21912,Q96RR1,P03886 8 +Spinal muscular atrophy 0.4892156248971284 1.0053134684969596 0.3147459317337189 1.0 0.6100980191500842 13 Q99720 1 +Pace of progression 0.3081244373350852 1.0038207213020542 0.3154650347182051 1.0 0.6105243495724237 158 Q9P0J0,Q13126,Q86U42,Q99720,Q9BQP7,Q8TD30,Q14108,Q9BUF5,O14653,Q8NHS3,P20700,P41440,Q9NR77,Q5XKP0,O95470,O14773,O95831,O95817,Q9BRK0,P54802,P50570,Q96RR1,Q96D71,Q03252,O60762,Q96RL7,Q8IY17,P57740,Q10713,P55263,P07196 31 +Glomerulopathy 0.525814620112049 1.0032786736248291 0.3157264229062095 1.0 0.6105243495724237 9 Q9NZ08,Q03252,Q14108 3 +Redundant neck skin 0.5427761147368391 1.001793675194094 0.3164432525752856 1.0 0.6105243495724237 6 Q9Y487 1 +Biliary tract abnormality 0.4142339763072612 1.0017830558701155 0.3164483825156845 1.0 0.6105243495724237 25 Q96J02,P09601,Q5XKP0,Q9NSD9,O43681,Q14108,Q10713,O96028 8 +Progressive external ophthalmoplegia 0.4990188361873304 1.0009822596128346 0.3168353851840788 1.0 0.6110107683626551 12 Q96RR1,P03886 2 +Abnormal atrioventricular conduction 0.5186632402983667 0.9999481713300804 0.3173355905545212 1.0 0.6117149894519068 10 P49748,P50402,O43772,Q8WXH0 4 +Tracheal stenosis 0.4825883846662664 0.995493076737119 0.3194965098166149 1.0 0.6138226057147327 4 Q96HY6,O60315 2 +Abnormal sputum 0.5414179779744261 0.9954479812158716 0.3195184322571629 1.0 0.6138226057147327 6 Q9NZ08,Q8NBM4 2 +Decreased activity of mitochondrial complex i 0.3802670112758142 0.9918864065437764 0.3212529408912614 1.0 0.6158594254072849 39 Q70HW3,Q96CU9,Q9Y584,Q9Y375,P03886,O96000 6 +Wide nasal ridge 0.5105196782639498 0.9897646108013266 0.3222891861251544 1.0 0.616576425383185 5 Q9BZK7 1 +Abnormal thalamic mri signal intensity 0.5348558305396462 0.9897291945308264 0.3223065012521955 1.0 0.616576425383185 7 Q12824,Q96RR1,Q96EY7,Q99496 4 +Abnormal cardiac ventricular function 0.4324355934966331 0.9884941068711804 0.3229107191816516 1.0 0.6174696318669827 20 P49748,O75844,P00403,Q96RR1,P03886,P04114 6 +Abnormal brainstem morphology 0.3370127078036867 0.9861361028408732 0.3240663294724148 1.0 0.6188956460834905 88 Q9Y3B2,O75380,O00429,P36405,P03886,O96000,P20700,P07437,Q9Y375,Q9UNW1,O43676,Q96S52,O95831,Q5KU26,Q92974,Q99496,Q96CU9,Q06787,Q9UP83,Q96RR1,Q96DA6,Q12824,O60762,O43819,Q8N183,Q9BVA1,Q10713,O43505 28 +Macular purpura 0.4615105785327345 0.9850800930066774 0.3245847308288367 1.0 0.6193634501493811 16 Q8NCH0,Q9BZK7,Q16625 3 +Elevated pulmonary artery pressure 0.4103251396971835 0.9841508587898872 0.3250413435766539 1.0 0.6199735942746283 26 O75844,Q71SY5,P51970,Q96AX1,Q8IZA0,P03886,Q14108,Q69YQ0,O96000 9 +Zonular cataract 0.515463815138577 0.98374949949883 0.3252386951320418 1.0 0.6200889263249788 10 Q9H6K4 1 +Stomatocytosis 0.4150760271756722 0.9832757291562416 0.3254717520742236 1.0 0.6202222675109687 2 P11166 1 +Head tremor 0.4739595777292245 0.98138251862893 0.3264041435332423 1.0 0.6209120449166066 14 Q96RL7,Q99720,P07196 3 +Hypoplasia of the frontal lobes 0.537774765057857 0.9784370731349944 0.3278581998430723 1.0 0.6224633886375178 6 Q86XL3 1 +Pediatric onset 0.2975056215173359 0.9743487263430975 0.3298834186519979 1.0 0.6252602035537868 218 Q9P0J0,Q70HW3,Q5JRX3,O15118,P23786,Q9BUF5,P49366,P49748,Q5BJH7,Q8NHS3,Q8WXI9,O75648,P20700,P41440,Q9NR77,Q96TA2,Q96AX1,Q5XKP0,Q9Y375,P35241,O14773,Q8N0X7,O95831,Q8WXH0,P54802,P22830,P50570,P51970,Q96CU9,Q9NSD9,Q92643,Q03252,O60762,O75787,Q8IY17,Q9H9P8,Q9UBB6,Q9BSJ2,Q9UEY8,P57740,Q10713,Q9NUQ7,P55263,P07196 44 +Spastic paraplegia 0.3366297495801504 0.9739985125733344 0.3300572777631949 1.0 0.6253280921234936 58 Q8IY17,Q9BRK0,Q7KZN9,P00846,Q96CU9,O95831 6 +Functional motor deficit 0.3063064243906178 0.9727817552490912 0.3306617822763316 1.0 0.6256883348837854 148 Q99720,Q9BQP7,Q9NWM8,P61978,P23786,Q8TD30,P03886,Q8NC96,O14653,P20700,Q9NR77,O43681,O14773,Q8N0X7,O95817,Q92974,P50570,P00846,Q96F07,Q9NSD9,Q96RR1,Q12824,Q96RL7,O95319,Q71SY5,O43819,Q05086,P07196 28 +Arthropathy 0.5068005181347134 0.9715670304371732 0.3312659911507967 1.0 0.6259222971481729 5 P40763,O15269,Q9Y3Z3,O15270 4 +Disturbance of facial expression 0.5065244093476718 0.9702169013376004 0.3319383878781832 1.0 0.6260120304280474 5 Q9NR77,P50570 2 +Nonprogressive 0.5058913533891294 0.9671218221262564 0.3334831376784981 1.0 0.6267288054011069 5 Q10713 1 +Abnormality of peripheral nerves 0.3657202898806383 0.9661617469379484 0.3339632509592301 1.0 0.626959604991841 43 Q13614,P50570,Q99720,Q9NR77,Q9Y619,O95831 6 +Limb ataxia 0.4103825002041727 0.9650468168965862 0.3345213630200039 1.0 0.6277472139522028 24 P41440,Q9NR77,Q10713,Q14108,O14773 5 +Juvenile onset 0.3667432696834865 0.9638283599156892 0.3351319857342836 1.0 0.6283724732517818 42 Q8NHS3,P54802,Q8IY17,P50570,P41440,Q9NR77,O15118,P57740,O14773 9 +Abdominal pain 0.3386458380202439 0.9561974820412188 0.3389724718348628 1.0 0.6334757827606965 76 Q13423,Q70HW3,Q14C86,Q9BZK7,P23786,Q9NZ08,P42892 7 +Retinal hemorrhage 0.532173818530088 0.9523215383858826 0.3409339378137908 1.0 0.6366161328509778 6 Q9Y487 1 +Pleural effusion 0.5268142328431804 0.951496068852822 0.341352613170623 1.0 0.6368728738315167 7 Q9NZ08,Q8NBM4,P52732 3 +Increased connective tissue 0.5209843546203727 0.950122025697544 0.3420502527436704 1.0 0.6371236148465022 8 O95831 1 +Generalized onset motor seizure 0.3441174981075956 0.9490166006442085 0.3426121690432846 1.0 0.6371236148465022 54 Q8NHS3,Q9Y619,P03886,P00846 4 +Abnormal urine ph 0.362225410281211 0.9467386561135662 0.3437719673783421 1.0 0.6380662028707763 44 P48735,P00846,P23786,O43772,P03886,Q9BQT8 6 +Upper limb muscle weakness 0.406140943212517 0.9439120874396724 0.3452145746416768 1.0 0.6390155605743318 25 P50570,P00846,P50402,Q8N0X7,Q12824,Q8WXH0,P07196 7 +Iris atrophy 0.4082821093497242 0.9437012869667404 0.3453223161779171 1.0 0.6390155605743318 2 O60315 1 +Multiple prenatal fractures 0.5250296631943668 0.943025340117165 0.3456679417137669 1.0 0.6393939469021495 7 Q32P28 1 +Subcutaneous hemorrhage 0.3744921302367845 0.9424730877483832 0.3459504832970952 1.0 0.639459248803681 39 Q9BXW9,Q13126,Q16625,Q9NWM8,Q9BZK7,Q14108,Q8NCH0,P38435 8 +Vocal cord paresis 0.4719974101650908 0.9411099592041918 0.3466485123596263 1.0 0.6399012880966208 4 O95140,P43243,Q8TB36 3 +Involuntary movements 0.2700852191306924 0.9394807357520064 0.3474839784280223 1.0 0.6400608265905706 322 Q9P0J0,Q9BWD1,Q99720,P61457,P03886,Q9Y4G8,Q14108,Q8NC96,P50897,Q08J23,Q03164,O14653,Q8WXI9,Q13045,P41440,Q6DKK2,Q9NR77,Q5XKP0,Q9UNW1,P13073,O14773,O95831,Q9BRK0,P00846,Q9Y5P4,Q96F07,O75503,Q96CU9,Q96RR1,Q86VD7,Q96RL7,Q8IY17,O43819,Q9UBB6,Q9Y619,Q9H6K4,Q05086,Q10713,Q9BQT8,Q9NUQ7 40 +Abnormality of the calf musculature 0.4875051104276143 0.9393923196911254 0.3475293548118556 1.0 0.6400608265905706 12 Q9NR77,P50570 2 +Heteronymous hemianopia 0.499202015894486 0.9344597699281 0.3500667787389582 1.0 0.6425455865832579 5 Q12824,Q99496 2 +Prolonged partial thromboplastin time 0.5282007601480223 0.93382677669283 0.350393254776137 1.0 0.6427515674120481 6 P38435 1 +Mitochondrial myopathy 0.3919146016566745 0.9303865794168352 0.3521709646895068 1.0 0.6445020186266592 32 P00846,Q96CU9,Q96RR1,Q9Y375,P03886 5 +Abnormal activity of mitochondrial respiratory chain 0.3339890303715565 0.9299080278058128 0.352418706150889 1.0 0.6445020186266592 61 Q9P0J0,Q7KZN9,Q70HW3,Q96CU9,Q9Y584,Q9Y375,P03886,P13073,O96000 9 +Restless legs 0.4981862178479512 0.9295073442242144 0.3526262209168163 1.0 0.6445020186266592 5 O43464 1 +Axonal loss 0.5272674415748395 0.92948616143949 0.3526371936714745 1.0 0.6445020186266592 6 P41440 1 +Abnormal thalamic size 0.4053704302814615 0.926778239437248 0.3540416853830215 1.0 0.6452937428147331 2 P11166 1 +Paraplegia 0.3327541245618736 0.9266118707218048 0.3541280893239351 1.0 0.6452937428147331 59 Q8IY17,Q9BRK0,Q7KZN9,P00846,Q96CU9,O95831 6 +Single naris 0.4365695792880305 0.9249762207002152 0.3549782768082394 1.0 0.6463229879185388 3 Q8N3U4,Q14683 2 +Abnormal morphology of the olfactory bulb 0.4365695792880305 0.9249762207002152 0.3549782768082394 1.0 0.6463229879185388 3 Q8N3U4,Q14683 2 +Impaired visuospatial constructive cognition 0.5203019267079352 0.9206122812137272 0.3572528879614087 1.0 0.6488995920068892 7 P03886 1 +Abnormal motor nerve conduction velocity 0.4292505610687823 0.918395414297489 0.3584118906136804 1.0 0.6490481374127685 19 Q99720,Q9NR77 2 +Semilobar holoprosencephaly 0.4674651990935451 0.9179069178671364 0.3586675996005939 1.0 0.6490481374127685 4 Q14683,A5YKK6,O94979 3 +Solitary median maxillary central incisor 0.4674651990935451 0.9179069178671364 0.3586675996005939 1.0 0.6490481374127685 4 Q6W2J9,A5YKK6,Q14683 3 +Abnormal peripheral nervous system physiology 0.3545475483563797 0.917493936297484 0.3588838689406777 1.0 0.6490481374127685 47 Q13614,Q96RL7,P20700,P50570,Q71SY5,Q99720,Q9NR77,Q9Y619,O95831,P07196 10 +Muscle spasm 0.3317137127896145 0.9153598862956764 0.3600027297786186 1.0 0.6502441650307584 59 P49748,P00846,Q9NR77,Q15165,Q9H6K4,Q92804,P23786 7 +Aplasia hypoplasia of the femur 0.4495378428823264 0.9139770282370164 0.3607289164714646 1.0 0.6510366500461094 16 Q96HY6,Q9Y2D4,Q9NR45,Q99575,O00116,O95831 6 +Long hallux 0.4344704794839319 0.9135590200303508 0.3609486078443011 1.0 0.651147417588735 3 O60762 1 +Heterophoria 0.402135231316721 0.9080051903499108 0.363875479414127 1.0 0.6536006485137132 2 Q7Z392 1 +Abnormal cranial nerve physiology 0.3343940521524948 0.9070702662165068 0.3643696405559677 1.0 0.6542189741254594 70 Q13614,Q8NBM4,Q86U42,Q9BQP7,Q9NZ08,Q9BUF5,Q92734,Q9NR77,Q96TA2,O96011,P38398,O95817,Q9H5V9,P50570,O75381,Q96RR1,Q12824,Q9BXW9,P48735,O43819,P07196 21 +Abnormality of salivation 0.3532200782367438 0.904988884788091 0.3654712757772067 1.0 0.6554255628027371 47 Q15165,Q14203,Q8TD30,P51812,Q15233,Q9NR77,P55795,Q8N0X7,Q9H5V9,Q9Y5P4,Q92804,Q03252,Q96RL7,O75787,P35670,P35637,O60315,Q9BVA1,Q05086 19 +Impaired pain sensation 0.4192930630137815 0.9023862198082516 0.3668517387243333 1.0 0.6572258803915151 20 Q9NR77,Q13045 2 +Progressive cerebellar ataxia 0.3666111613013254 0.9022673865634124 0.3669148458079783 1.0 0.6572258803915151 40 Q7KZN9,P41440,Q9Y619,Q96CU9,Q9Y487,O14773 6 +Upper airway obstruction 0.4640796501059042 0.9006065659073743 0.3677975423239898 1.0 0.6572476791825145 4 Q96HY6 1 +Abnormality of the autonomic nervous system 0.3370002933311566 0.8993314979819959 0.3684761147624511 1.0 0.6582006308651039 55 Q96RL7,Q9Y2B2,Q9BXW9,Q92766,P20700,P41440,O43464,P36405,Q96RR1,O43681,P38398,Q10713,P21964,P42892 14 +Multifocal cerebral white matter abnormalities 0.4916322371268236 0.8976074504601089 0.3693948655807326 1.0 0.6590458015267668 5 Q9Y619 1 +Micropenis 0.3300596436037112 0.8974807709341789 0.3694624296560316 1.0 0.6590458015267668 59 Q9BXW9,Q8IY17,P48449,Q9Y619,Q9BZK7,Q9UP83,O95470,Q9Y3Z3,Q9UNW1,Q9BPU6,Q10713,P42892,O60566,Q03252 14 +Joint contracture of the hand 0.3523751909364323 0.8970340555626425 0.3697007450192275 1.0 0.6590886953707599 47 Q9Y2B2,Q71SY5,Q9NR77,Q9Y619,Q8IZA0,Q15392,Q9UP83,P57740,Q99567,P42892,P07196 11 +Abnormality of the phalanges of the hallux 0.4310679611650532 0.8950793028535078 0.3707446970321248 1.0 0.6604299951063806 3 Q6DKJ4,Q8WVQ1 2 +Aplasia hypoplasia of the uvula 0.5191283219093094 0.8917057560354147 0.3725506675042558 1.0 0.6630008369670366 6 Q9NVI1,Q9BXW9,P38398,Q01082 4 +Abnormal caudate nucleus morphology 0.4959655056276404 0.8854261244072172 0.3759268475531738 1.0 0.6663029180547961 10 Q96RL7,P00846 2 +Limb muscle weakness 0.3320300600945247 0.8835960255581753 0.3769143252947509 1.0 0.6670118176920152 79 Q96RL7,Q8IY17,Q13126,P00846,P50570,Q99720,Q9NR77,Q96RR1,Q9BQT8 9 +Abnormal renal cortex morphology 0.3509415078260797 0.8835435549206073 0.3769426607707635 1.0 0.6670118176920152 47 Q8NBM4,P00846,Q14C86,P00403,Q96AX1,Q8N1F7,P21912,P57740,Q9NZ08,O95470,P03886,Q14108,Q03252 13 +Aplasia hypoplasia of the patella 0.5120914469256415 0.8817974546588592 0.3778863483599504 1.0 0.6684206005742191 7 Q9Y619 1 +Sensory neuropathy 0.3756395606235034 0.8788936236610282 0.3794589562740815 1.0 0.6694407292191552 36 O95831,Q96RR1,P03886,P00846 4 +Rapidly progressive 0.4856192353792067 0.8788875579162884 0.3794622454650884 1.0 0.6694407292191552 11 Q8NHS3,Q14108 2 +Nephrolithiasis 0.4154689566964233 0.8774356510152901 0.3802500561402442 1.0 0.6696413079669641 20 Q8NCH0,Q9BQP7,Q4J6C6 3 +Fatigue 0.3316760249353337 0.8773295594202574 0.3803076612545821 1.0 0.6696413079669641 78 Q13423,Q70HW3,Q15165,Q4J6C6,Q92804,Q9BZK7,Q9NZ08,Q96RR1 8 +Neoplasm of the tongue 0.4874388977645889 0.8772509457790838 0.3803503499777039 1.0 0.6696413079669641 5 Q12824,Q99496 2 +Abnormal nerve conduction velocity 0.3634651757335596 0.8750443174136634 0.3815497926247528 1.0 0.67123128566607 40 Q13614,Q99720,Q9NR77,Q9Y619,O95831 5 +Abnormality of ocular smooth pursuit 0.3987620486744532 0.8698436835539541 0.3843858352126923 1.0 0.6734542101828493 22 P41440,O14773 2 +Microcornea 0.3898315652556662 0.8695679265563186 0.384536571909871 1.0 0.6734542101828493 29 Q13045,Q71SY5,Q6W2J9,P07437,Q9NWM8,Q9UQE7,Q9BZK7,Q8NCH0,P52732 9 +Long palpebral fissure 0.3930135266454507 0.8694567394405486 0.3845973602081747 1.0 0.6734542101828493 27 O00459,Q9Y2B2,Q8WXI9,Q9H5V9,P20700,Q13555,P61978,Q5KU26 8 +Night sweats 0.3953413134907745 0.8687002809349427 0.3850110877287676 1.0 0.6739181713335846 2 Q9UJS0 1 +Abnormal anterior chamber morphology 0.4851366896864433 0.8660945955770175 0.3864382886855182 1.0 0.6758939952684933 5 Q8NCH0 1 +Abnormal vascular physiology 0.3420992075793326 0.865773407208502 0.3866144351031804 1.0 0.6759411003540746 51 O75844,Q8NBM4,Q71SY5,P51970,Q9NWM8,Q96AX1,Q8IZA0,Q9NZ08,Q9Y3Z3,P03886,Q14108,O96000 12 +Abnormal pleura morphology 0.4532545189667603 0.8640497506144968 0.3875605611825601 1.0 0.6770726348465088 14 Q8NCH0,Q9NZ08,P52732 3 +Abnormal growth hormone level 0.3889504016819549 0.8630211678103646 0.3881258287032012 1.0 0.6773736163538082 29 Q8IY17,Q4J6C6 2 +Abnormal urine protein level 0.3377032840091518 0.8617709079172942 0.3888135969225859 1.0 0.6774702745801678 53 P35670,Q14C86,P09601,Q96AX1,P00403,Q8N1F7,P21912,P57740,O95470,P03886,Q14108,P35579,O75431,Q03252 14 +Platybasia 0.4842355929067434 0.8617319561964464 0.3888350361828778 1.0 0.6774702745801678 5 Q92766 1 +Foot dorsiflexor weakness 0.3885250221250667 0.8598621092479797 0.3898650574251823 1.0 0.6787427786841183 29 Q99720,Q9NR77,Q9BQT8 3 +Medulloblastoma 0.5113508986651383 0.8557430182871184 0.392139939782147 1.0 0.6816553826604475 6 P42771,Q14145,Q12824 3 +Neoplasm of the thyroid gland 0.3924297257904043 0.8552180819420047 0.3924304277527941 1.0 0.6818986719294812 26 P42892 1 +Short sternum 0.4234346734046261 0.8537578676701751 0.3932391635136487 1.0 0.6826625833136359 3 O60566 1 +Peripheral axonal neuropathy 0.3368365861095218 0.8530460046305036 0.3936337927737765 1.0 0.6826625833136359 53 Q8IY17,P50570,P00846,Q96RR1,P03886,O95831 6 +Abnormality of the cerebrospinal fluid 0.2989251337905804 0.8527893695915996 0.3937761200758756 1.0 0.6826625833136359 145 Q9P0J0,O75380,P36405,P23786,Q9Y3Z3,P03886,O96000,Q08J23,O00459,P20700,Q16625,Q9NR77,Q96AX1,Q15392,Q9Y375,P38398,P13073,O43681,O95831,P00846,O43464,P51970,Q96CU9,Q9Y2V7,Q12824,Q03252,Q9BXW9,Q92766,Q7KZN9,O43819,Q10713,P21964,O43678,O96028 34 +Hypoventilation 0.4805004919200809 0.8525210817440582 0.3939249432189502 1.0 0.6826625833136359 11 Q8N183,O75380,P61978,O43819 4 +Genetic anticipation 0.3921061145260393 0.8500475370434435 0.3952986576201249 1.0 0.6839965313289404 2 Q9UBB4 1 +Short foot 0.3902860237182757 0.8496746280298255 0.3955060082396497 1.0 0.6840940119609062 27 Q9Y2B2,Q08J23,Q9Y5P4,Q13555,Q9UQE7,Q9BZK7,Q06787,Q9Y4R8,Q93009,Q8N0X7,Q99496 11 +Abnormality of the temporomandibular joint 0.4536278661379348 0.8474013743507276 0.3967714387154801 1.0 0.6841041112293927 4 Q96RL7 1 +Glomerular sclerosis 0.3847774532969628 0.8450848779877704 0.3980634507570322 1.0 0.6849966951000545 30 Q14C86,P00403,Q96AX1,Q8N1F7,P21912,P57740,O95470,P03886,Q14108 9 +Platyspondyly 0.3764226157867849 0.8449390356469365 0.3981448781895018 1.0 0.6849966951000545 34 Q96HY6,P48735,Q32P28,Q9NUQ7,Q96AY3,O95831 6 +Abnormal oral physiology 0.3256294769098273 0.844098902843489 0.3986141407643644 1.0 0.6855436817245902 60 Q15165,Q14203,Q9BZK7,Q8TD30,P51812,Q15233,Q9NR77,P55795,P50995,Q8N0X7,Q9H5V9,Q6W2J9,Q9Y5P4,Q92804,Q03252,Q96RL7,O75787,P35670,P35637,O60315,Q9BVA1,Q05086 22 +Abnormal c peptide level 0.4528973777921527 0.843695732991158 0.398839452570243 1.0 0.6856708615344216 4 O00330,A5YKK6,Q16836 3 +Sparse lateral eyebrow 0.4930667328959665 0.8418368986123477 0.3998792549621701 1.0 0.6871976574274016 9 Q08J23,P61978,Q9Y2V7 3 +Retinal dystrophy 0.3372855175187409 0.8373615165636099 0.4023893903938051 1.0 0.6907484933616557 52 Q8NHS3,Q8WWY3,Q8IY17,P00846,O96011,P03886,Q10713,Q9NQT5,P04114,P38435,P52732 11 +Subcutaneous nodule 0.4364279792684217 0.8366074961068436 0.4028132306402447 1.0 0.690929168799814 16 P48735,Q8NBM4,O75874,P21912,Q9NZ08,P52732 6 +Neurodegeneration 0.3906960369856406 0.8341049098872247 0.4042218686127186 1.0 0.6919163473448194 25 Q6DKK2,Q8NHS3,Q15165 3 +Retinal arteriolar tortuosity 0.4854999873758951 0.8330335042128146 0.4048258338251589 1.0 0.6919163473448194 10 Q92766,P00846 2 +High frequency sensorineural hearing impairment 0.4505851156061643 0.8319783450359023 0.4054211677634702 1.0 0.6923133048078219 4 Q9NWM8 1 +Thick corpus callosum 0.4192922661313989 0.8314234319440041 0.4057344664387763 1.0 0.6925309468604585 3 O00459 1 +Aplasia hypoplasia of the sternum 0.4771430874441081 0.8274788004246978 0.4079657330547368 1.0 0.695553169265321 5 O60566,Q9Y619 2 +Muscle abnormality related to mitochondrial dysfunction 0.3546947181547575 0.8266954504115532 0.4084097007025007 1.0 0.6959887456829343 41 O75648,Q9BUK6,P00846,P00403,O75380,Q96CU9,Q9Y375,P03886,O43676,Q96RR1,O96000 11 +Abnormal circulating fatty acid concentration 0.4000501209286113 0.8255608327781538 0.4090532610247037 1.0 0.6963589900195069 21 P49748,O75648,P23786,O96011,O43772 5 +Paraparesis 0.3867962961455913 0.8244210498174321 0.4097003583711611 1.0 0.6965543383601077 27 O75787,Q6W2J9,Q6DKK2,Q9Y619,Q9H6K4,Q5XKP0,Q9Y3Z3,Q8N0X7 8 +Papillary renal cell carcinoma 0.5044689776128048 0.8240542592857097 0.4099087284485176 1.0 0.6965543383601077 6 Q9UNW1 1 +Emg impaired neuromuscular transmission 0.4490126254451147 0.8240208108435596 0.40992773331222 1.0 0.6965543383601077 4 O60313,O75340,Q9H553 3 +Acetabular dysplasia 0.4947332170238113 0.8237529202438546 0.4100799633144776 1.0 0.6965543383601077 8 Q9Y584 1 +Neoplasm of the larynx 0.4486888960828653 0.822383734178248 0.4108585338691033 1.0 0.6970745911711753 4 P42771,P04637,P43246 3 +Choreoathetosis 0.3777722131240126 0.8212532094216756 0.4115020538134053 1.0 0.6976479040445979 32 Q96RL7,P00846,Q9H6K4,Q5XKP0,Q86VD7 5 +Morphological abnormality of the corticospinal tract 0.4333727790658102 0.8186720790775661 0.4129735307398552 1.0 0.6987264951137327 16 Q13045 1 +Abnormality of the peripheral nervous system 0.3194270182519055 0.8180687401340027 0.4133179372629927 1.0 0.6987264951137327 96 Q13614,Q96RL7,Q9BXW9,Q92766,Q71SY5,P50570,P20700,P41440,O43464,Q99720,Q9NR77,Q9Y619,Q96RR1,Q10713,O43681,P42892,O95831,P07196 18 +Abnormality of the curvature of the vertebral column 0.2629839154151005 0.8172262562963291 0.4137991403504086 1.0 0.6987264951137327 309 Q13614,Q32P28,Q99720,Q9BQP7,Q9NWM8,P61978,Q9BZK7,P36405,P50402,Q9HC07,Q9Y3Z3,Q14108,Q96AY3,Q08J23,O14653,O00459,Q5BJH7,O75648,Q13045,P20700,Q9Y2D4,O75718,Q9NR77,Q96AX1,Q9Y487,Q96PU5,Q9Y375,P38398,Q8NCH0,O95831,Q99575,Q5KU26,O95817,Q8N0X7,Q96HY6,Q96J02,Q8WXH0,Q9Y2B2,Q9Y2D2,Q9BUK6,P50570,Q8NFF5,Q6W2J9,P48449,P51571,Q96CU9,P21912,Q9NSD9,Q99567,O96028,Q9BPU6,Q12824,Q03252,Q9BXW9,P48735,Q92766,Q71SY5,O75844,O75787,Q05086,P57740,Q10713,Q9BQT8,P21964,Q9NUQ7,P07196,P78318 67 +Dementia 0.3290396782353927 0.8171593877387381 0.4138373479889945 1.0 0.6987264951137327 55 Q96RL7,Q8IY17,P20700,P00846,O43464,O15118,Q9Y487,Q96RR1,P03886,Q14108 10 +Purpura 0.3986082932533418 0.8159676264995956 0.4145186516912607 1.0 0.6992392882109714 21 Q8NCH0,Q9BZK7,Q16625,P38435 4 +Abnormal cellular phenotype 0.2940545030696133 0.8152873852083307 0.4149078278541762 1.0 0.6994910532859763 193 Q9UJW0,Q9P0J0,Q70HW3,Q9BQP7,O75380,Q4J6C6,P23786,O43772,P03886,Q14108,O96000,P02786,P49748,O75648,Q16836,Q96AX1,P28070,Q9Y375,P38398,O43676,O14773,P13073,Q96J02,Q96DF8,P00846,P51970,P17812,P09601,P00403,O75503,Q96CU9,P21912,Q9Y584,Q96RR1,Q9Y2V7,Q92643,Q12824,P33991,Q9BXW9,O75844,Q92766,O75787,Q7KZN9,Q9NRW7,P21964,O43678 46 +Erythrocyte inclusion bodies 0.474417098445594 0.8143569440980057 0.4154404966533482 1.0 0.699607973918092 5 O14936,Q9Y606,Q13586,P08865 4 +Poikilocytosis 0.4322724129518804 0.8122226151151014 0.4166639050777343 1.0 0.7003664155852083 16 Q96RL7,P41440 2 +Abnormal joint morphology 0.2732634274354123 0.8073286719558037 0.4194771493367621 1.0 0.7031299650011971 263 Q8NBM4,P23786,P50402,Q9NZ08,Q9Y3Z3,Q14108,Q9NQT5,Q96AY3,P42892,Q03164,P10321,O00459,Q9Y2D4,O75718,Q9NR77,Q96AX1,Q15392,P28070,Q9Y487,Q96PU5,P38398,Q8NCH0,O95831,Q99575,O95817,Q8WXH0,Q8N0X7,Q96HY6,Q9Y2D2,Q96J02,Q9Y2B2,Q86XL3,Q6W2J9,Q8IZA0,Q9NR45,O94979,P51571,P21912,Q9Y584,P49902,Q9UP83,Q9BPU6,Q9Y5S9,Q99567,P38435,Q03252,O60762,Q96RL7,Q9BXW9,O75844,Q92766,Q71SY5,Q5JTV8,O75787,P35670,Q9Y619,Q9H6K4,Q05086,Q9UQE7,P57740,Q9Y4R8,P21964,O96028,Q9NUQ7,P07196 65 +Weakness of facial musculature 0.3208874214575953 0.8047173313685894 0.4209828159501672 1.0 0.7052707678455093 58 Q13614,P50570,O43819,Q86U42,O75381,Q9BQP7,Q96TA2,O96011,Q96RR1,Q9BUF5,Q9BQT8,O95817,P07196,Q86VD7 14 +Abnormality of pain sensation 0.383811741945659 0.802878984172256 0.422044684101029 1.0 0.706788324945531 27 O95831,Q8NCH0,Q9NR77,Q13045 4 +Elevated hepatic transaminase 0.3159970237963663 0.8018391696675476 0.4226459974647536 1.0 0.7074446582544075 100 P49748,Q96RL7,P50416,Q16625,Q9Y619,Q5XKP0,P23786,P28070,O43772,Q9NSD9,Q96RR1,Q10713,Q9Y2V7,P55263 14 +Erythema 0.4364595109511818 0.801661247505323 0.4227489381665963 1.0 0.7074446582544075 15 P03886 1 +Abnormal basal ganglia mri signal intensity 0.3744054937402617 0.7954348369028199 0.4263606021151254 1.0 0.7109364061468959 32 P03886,Q96CU9,P00846 3 +Episodic pain 0.4603163931296785 0.7952836817920338 0.4264485036270122 1.0 0.7109364061468959 12 P23786 1 +Acanthosis nigricans 0.4692916627241269 0.7950888094620921 0.4265618436881375 1.0 0.7109364061468959 11 P28070 1 +Gonadal dysgenesis 0.4769689980636679 0.7905897344011016 0.429183439215159 1.0 0.7130714306802874 10 Q96RR1,Q9UNW1 2 +Abnormal tendon morphology 0.2886600385892904 0.7902908561938342 0.4293579256275397 1.0 0.7130714306802874 214 Q99720,P23786,Q96B26,P50897,P04114,Q96AY3,Q08J23,P42892,Q9NQT5,O00459,P20700,P41440,Q9Y2D4,Q9NR77,Q96AX1,Q15392,P28070,Q96PU5,Q8NCH0,Q99575,O95831,O95817,Q8N0X7,Q8WXH0,Q96J02,Q9Y2B2,Q86XL3,P50570,P48449,Q8IZA0,Q9UP83,P49902,Q99567,O60762,Q71SY5,Q9Y619,P57740,Q9H267,P07196 39 +Abnormal pancreas size 0.4925469863901449 0.7901174231166324 0.4294591955203124 1.0 0.7130714306802874 7 Q9Y3E5,Q9Y3A5,P40763,Q7Z2Z2,O00330,P61011 6 +Absent testis 0.4692132344671539 0.7893812689132637 0.4298892002622219 1.0 0.7130714306802874 5 Q9BXW9,P38398 2 +High narrow palate 0.3802361738874433 0.7872184282648046 0.4311540112833907 1.0 0.7146460560240614 28 P23786,Q9Y619,P61978,O60762 4 +Gaze evoked nystagmus 0.4759754529351381 0.7856642685030999 0.4320642018069436 1.0 0.7153396036788966 10 P41440 1 +Limited wrist movement 0.440930609884224 0.7832757124599492 0.4334652224338864 1.0 0.7160353431776896 4 Q9H6K4 1 +Dyspnea 0.3160871403366933 0.7805760045644887 0.4350519092607994 1.0 0.7171707237814487 97 P49748,P00846,O43819,P51970,Q9BQP7,Q9Y619,Q15165,Q92804,P23786,Q9BZK7,Q96RR1,P03886,P04114,O95831 14 +Hand muscle weakness 0.4800004480143189 0.7782285820915908 0.4364342696927994 1.0 0.7186649370077721 9 Q9NR77 1 +Extramedullary hematopoiesis 0.4392972842774693 0.7750750929173568 0.4382952882677267 1.0 0.7204200492934694 4 P98175,Q9NRW7 2 +Sudden loss of visual acuity 0.3788417987706284 0.7740976407033685 0.4388730525771371 1.0 0.7204518716091697 2 P35222 1 +Abnormality of upper limb joint 0.3045516873776161 0.7737453848435213 0.4390813754558089 1.0 0.7204518716091697 112 P23786,Q96AY3,P42892,Q03164,Q9Y2D4,Q9NR77,Q15392,Q99575,O95831,Q8WXH0,Q96J02,Q9Y2B2,Q8IZA0,Q9NR45,Q9UP83,Q99567,O75844,Q71SY5,Q9Y619,Q9H6K4,Q9UQE7,P57740,O96028,Q9NUQ7,P07196 25 +Limitation of movement at ankles 0.4386475918303885 0.7718164786872015 0.4402231303784065 1.0 0.7204518716091697 4 Q05086 1 +Impaired t cell function 0.4644532915492937 0.7704476309447859 0.4410344084689974 1.0 0.7212886034780489 11 P17812,Q92766,P21964,Q9Y2V7 4 +Chronic sinusitis 0.4375749894936007 0.7664409926606295 0.4434139494402842 1.0 0.7238433120592748 4 Q03518 1 +Large for gestational age 0.4774044684331193 0.7656669431260492 0.4438745011620313 1.0 0.7239010842693482 9 P31751,P50570 2 +Abnormal femoral neck head morphology 0.3410342327661823 0.7652874932387443 0.4441003697809347 1.0 0.7239010842693482 45 Q96HY6,O75718,Q9Y619,Q99575,Q9NUQ7,Q9Y487,Q96AY3,O95831 8 +Skeletal muscle atrophy 0.2938728564532289 0.7652258037199948 0.4441370968412022 1.0 0.7239010842693482 156 Q13614,Q13126,Q99720,Q9BQP7,Q9NWM8,Q15165,Q96B26,Q6P4A7,Q9NQT5,O00459,Q6DKK2,Q9NR77,Q9UNW1,Q8N0X7,O95831,Q8WXH0,O95817,P50570,P51970,Q92804,Q99567,Q96RL7,P83436,Q8IY17,Q71SY5,O43819,P50416,Q9BQT8,P55263,P07196 30 +Impaired social interactions 0.3318160372615786 0.7650389565216442 0.4442483475207037 1.0 0.7239010842693482 51 Q9P0J0,Q96CU9,Q5XKP0,Q9Y375,P03886,Q96RR1,O96000,Q5KU26 8 +Broad phalanx of the toes 0.4914790660578709 0.7646489950521276 0.4444805856882194 1.0 0.7240190770110155 6 Q71SY5,Q7LGA3,Q6DKJ4,Q9H936 4 +Ectropion of lower eyelids 0.3769006793917827 0.7630649616734223 0.445424654924222 1.0 0.7244760757949262 2 Q99496 1 +Cerebellar atrophy 0.2930006747019635 0.7625686089748631 0.4457207115321102 1.0 0.7244760757949262 138 Q9BQP7,Q5JRX3,Q14108,Q9NQT5,Q5BJH7,Q8NHS3,O75648,P41440,Q6DKK2,P07437,Q5XKP0,P13073,O14773,Q8N0X7,P51970,Q96F07,O75503,Q96CU9,Q9UP83,Q96RR1,Q9Y2V7,Q96D71,Q92643,O60762,P83436,O75787,Q8IY17,P51572,Q9H6K4,Q10713 30 +Chronic fatigue 0.4817421684745835 0.7619722091759331 0.4460765908926816 1.0 0.724794460811997 8 P38398,P30038,P42771,Q13423 4 +Abnormal exteroceptive sensation 0.3346254052394649 0.759338887003806 0.4476498610038479 1.0 0.7263263002657375 49 P54802,Q13045,Q9NR77,P61978,Q9H6K4,Q9NZ08,Q8NCH0,O95831 8 +3 methylglutaconic aciduria 0.452456976667309 0.7541351992264314 0.4507680433514855 1.0 0.7303216153012266 12 Q5XKP0,Q9H6K4 2 +Abnormality of the basal ganglia 0.3178692689309045 0.7518308478654672 0.452152788433374 1.0 0.731644625984384 89 Q96RL7,Q7KZN9,P00846,O43819,Q9UBB6,Q96CU9,Q9NUQ7,P23786,P03886,Q08J23,O95831 11 +Hypoplastic heart 0.4607697549827741 0.7490855716551351 0.4538056307810918 1.0 0.7331453307554728 5 O43791 1 +Abnormal autonomic nervous system physiology 0.3717356564149477 0.7477306799354346 0.4546226217744773 1.0 0.7342033784807066 30 Q96RL7,P20700,P41440,O43464,P42892 5 +Psychosis 0.3699630185646596 0.747369797113837 0.4548403714829969 1.0 0.7342858297873154 31 O15118,Q6DKK2,Q96RR1,P03886 4 +Abnormality of the tonsils 0.4783231253349718 0.745821451062265 0.4557752799861259 1.0 0.7342858297873154 8 P31751,Q92766 2 +Sepsis 0.4084141089528876 0.7456967455545632 0.4558506255726264 1.0 0.7342858297873154 18 P42892,P02786 2 +Polymicrogyria 0.320240668006271 0.7448954790805558 0.4563349083836443 1.0 0.7346116328990436 71 O00459,Q71SY5,Q9UBB6,Q16625,P07437,Q15392,P23786,Q9Y487,O96011,Q10713,Q08J23,Q9NUQ7 12 +Arthralgia 0.3692019599893493 0.7416552290663099 0.4582962521184082 1.0 0.7369833234278981 31 Q96HY6,P28070,Q9NZ08,P04114,Q15800,Q9NUQ7,Q03252 7 +Irritability 0.3198343929333316 0.7375344539904978 0.4607973988839084 1.0 0.7389069794492409 73 Q96RL7,Q5BJH7,P00846,Q14C86,P61457,O43772,Q9NZ08,O95831,Q5KU26 9 +Abnormal facial expression 0.366373482874729 0.7341714449679082 0.46284425449081 1.0 0.7416641219820904 32 Q8WXI9,P50570,Q9Y5P4,Q9NR77,Q05086,Q96RR1 6 +Clonus 0.3679854075246185 0.7325306339087122 0.4638447520043911 1.0 0.7429501200312885 31 Q99720,Q9Y619 2 +Subcapsular cataract 0.457123291606603 0.7317800570522406 0.4643028233573019 1.0 0.7429501200312885 5 Q9H6K4 1 +Brisk reflexes 0.3759523329375014 0.7305014177260651 0.4650837466996267 1.0 0.7437687362534581 25 Q9UP83,Q99720,Q5JRX3,Q10713 4 +Abnormality of the pulmonary veins 0.4749462928703947 0.7299200709738606 0.4654390430296198 1.0 0.7437687362534581 8 P62244,O75718,Q15392,Q9NVR5 4 +Abnormality of the phalanges of the toes 0.412029060991147 0.7293304709275715 0.4657995374726402 1.0 0.7437687362534581 17 Q9Y2B2,O75844,Q9BXW9,Q71SY5,Q9NVI1,P38398,O75431 7 +Peripheral edema 0.4000000000000044 0.7284623174015192 0.466330627860267 1.0 0.7438929776154146 3 Q14315,O95235 2 +Abnormal circulating proteinogenic amino acid derivative concentration 0.3745534424755669 0.7280472949763878 0.4665846353281875 1.0 0.7439733889604679 26 Q5XKP0,Q9P0J0,P03886,P00846 4 +Eeg with abnormally slow frequencies 0.4113735409471892 0.7254510204480491 0.4681753826022063 1.0 0.7444100058833468 17 P20700,Q96F07,O75503,Q05086,Q8NC96 5 +Tics 0.4785000816616168 0.7250467269958527 0.4684233647256843 1.0 0.7444100058833468 7 Q96RL7 1 +Aplasia hypoplasia involving the carpal bones 0.4826007377698548 0.7244116074711469 0.4688130758140443 1.0 0.7444100058833468 6 Q9Y2D4,Q9NR45 2 +Carpal bone hypoplasia 0.4826007377698548 0.7244116074711469 0.4688130758140443 1.0 0.7444100058833468 6 Q9Y2D4,Q9NR45 2 +Nasal congestion 0.3697832416693613 0.7228218840569954 0.4697893205670875 1.0 0.7444100058833468 2 Q9NVR5 1 +Abnormal atrial arrangement 0.3697832416693613 0.7228218840569954 0.4697893205670875 1.0 0.7444100058833468 2 Q9NVR5 1 +Wheezing 0.3697832416693613 0.7228218840569954 0.4697893205670875 1.0 0.7444100058833468 2 Q9NVR5 1 +Abnormal respiratory motile cilium morphology 0.3697832416693613 0.7228218840569954 0.4697893205670875 1.0 0.7444100058833468 2 Q9NVR5 1 +Abnormal respiratory motile cilium physiology 0.3697832416693613 0.7228218840569954 0.4697893205670875 1.0 0.7444100058833468 2 Q9NVR5 1 +Abnormal nervous system electrophysiology 0.2908568538747724 0.7204794533231329 0.4712298458967914 1.0 0.7456064274930021 171 Q13614,Q99720,P03886,Q14108,P50897,Q8NC96,Q08J23,P49366,Q8NHS3,Q13045,P20700,Q9NR77,O96011,O43681,P13073,O14773,O95831,Q9Y2B2,P50570,O75381,Q96F07,P48449,O75503,O60762,Q96RL7,O95319,Q71SY5,Q9UBB6,Q9BSJ2,Q9Y619,Q05086,P57740,P21964,Q9NUQ7,P07196 35 +Neoplasm of the endocrine system 0.3480997891161543 0.7188014862875509 0.4722632417774826 1.0 0.7463320629483235 39 P42892,Q9UNW1 2 +Encephalopathy 0.3079743242240027 0.7186180090769063 0.4723763140578032 1.0 0.7463320629483235 103 Q7KZN9,Q96F07,Q9Y619,Q96CU9,P23786,O43772,Q9Y375,P03886,Q96RR1,Q8NC96,Q5KU26 11 +Abnormal patella morphology 0.3730382624118871 0.7173753801059242 0.4731425066328731 1.0 0.7463341872230819 26 Q92766,Q9Y2D4,Q9Y619,Q96PU5,Q96AY3 5 +Decreased number of peripheral myelinated nerve fibers 0.4216040240264264 0.717301805885087 0.4731878931927271 1.0 0.7463341872230819 15 Q96RL7,Q9NR77,P50570 3 +Abnormality of the lymph nodes 0.3614793623373776 0.7116296380844805 0.4766941489418732 1.0 0.7482413356572023 33 Q9BZK7,P28070,Q9UNW1 3 +Deviation of the 2nd finger 0.4794505740934566 0.7102164509728669 0.4775699207938095 1.0 0.7490968632949991 6 Q9H6K4 1 +Retinal dysplasia 0.4790140913161941 0.7082531890643174 0.4787880410312952 1.0 0.749709583778696 6 P07437,Q10713,P52732 3 +Hyperreflexia 0.2791047204245681 0.7043152305648079 0.4812364834445901 1.0 0.752762869476517 233 Q9P0J0,Q99720,Q5JRX3,Q9NZ08,Q8TD30,P03886,Q9NQT5,Q08J23,P20700,Q16625,Q9NR77,Q6DKK2,Q5XKP0,O96011,Q9UNW1,P13073,O14773,O43681,Q96IX5,Q8N0X7,O95831,Q5KU26,Q8WWY3,Q9BRK0,Q86XL3,P00846,O43464,O75381,Q96F07,O75503,Q96CU9,P49902,O60762,Q9BXW9,Q8IY17,Q7KZN9,Q9Y619,Q9H6K4,Q05086,Q10713,Q9BQT8 41 +Metaphyseal widening 0.3951272984517042 0.7035548441912832 0.4817100408099686 1.0 0.7532267927129579 19 Q96HY6,Q9Y2D4,O95831,Q9NR45 4 +Disproportionate short stature 0.3717769215037173 0.7014583404790733 0.4830170243707781 1.0 0.7545059035860775 25 Q32P28,O75718,Q03164,Q96HY6 4 +Conjugated hyperbilirubinemia 0.3938780751684279 0.6962345286425077 0.4862819672522567 1.0 0.7573712414672645 3 Q9H267 1 +Hyperammonemia 0.3544252203053898 0.6893958513023942 0.4905741934773318 1.0 0.7611907511241465 35 P49748,Q9Y619,P23786,O43772,Q86VD7 5 +Spasticity 0.2569871603213547 0.6889969193868379 0.4908252061884397 1.0 0.7611907511241465 306 Q9P0J0,Q99720,Q15165,O15118,Q96B26,Q8TD30,P03886,P50897,Q8NC96,Q9NQT5,Q08J23,P52732,P49366,Q5BJH7,Q8WXI9,P20700,Q16625,Q6DKK2,Q5XKP0,Q15392,Q9Y487,O96011,Q9UNW1,O43681,Q8N0X7,O95831,Q5KU26,Q9BRK0,Q86XL3,P00846,O43464,P51970,Q96F07,O75381,O75503,Q96CU9,Q92804,P49902,Q96D71,O60762,O95319,O75787,Q8IY17,Q71SY5,Q7KZN9,O43819,Q9H9P8,Q9UBB6,Q9Y619,Q9H6K4,Q9UEY8,Q10713,Q9NUQ7,P07196 54 +Abnormal sella turcica morphology 0.4742696366022993 0.6869720564234633 0.4921003376181732 1.0 0.7620469359188625 6 O60568,O75431,Q96AX1 3 +Red eye 0.4048339775002661 0.6869125944614692 0.4921378098652837 1.0 0.7620469359188625 17 P02786,P28070,Q9NZ08,Q96AX1 4 +Retinal detachment 0.4214046650312418 0.6868095472854138 0.4922027526394781 1.0 0.7620469359188625 14 Q13045,Q6W2J9,Q8NCH0,P04439,P52732,O43505 6 +Abnormal thyroid morphology 0.3442665791109642 0.6867847262420887 0.4922183961365545 1.0 0.7620469359188625 39 P42892,P48735,Q96RR1,Q9UNW1 4 +Abnormal circulating nitrogen compound concentration 0.3236110856291297 0.6853655837965138 0.4931132559745075 1.0 0.7629108775835106 51 P49748,Q9Y619,P61457,P23786,O43772,Q86VD7 6 +Broad foot 0.4551650102619549 0.6835237969507294 0.4942759183393095 1.0 0.7639269566963739 10 O95831 1 +Loss of subcutaneous adipose tissue in limbs 0.4206787605087267 0.6825539815897865 0.494888721188671 1.0 0.7642833599650606 4 O75844,Q03252 2 +Vestibular dysfunction 0.3656425843205834 0.6818242346032078 0.4953500982025205 1.0 0.7642833599650606 28 P41440,Q9BZK7,Q9NZ08 3 +Ecchymosis 0.4295807196035638 0.6811620817697296 0.4957689380288683 1.0 0.7646691485429942 13 Q9BZK7,Q8NCH0 2 +Focal t2 hyperintense brainstem lesion 0.3843198248536888 0.6770952422597569 0.4983455273888757 1.0 0.7676535069337598 20 Q9Y375,P03886,Q96CU9 3 +Arthritis 0.3374454587426316 0.6770382755984999 0.4983816697333747 1.0 0.7676535069337598 41 Q96HY6,Q96RL7,O75844,Q92766,Q8NBM4,P28070,Q9NZ08,Q14108,P21964,Q9NUQ7,P10321 11 +Intellectual disability progressive 0.4537639542705133 0.6767277561189923 0.4985787024860078 1.0 0.7676959626993934 10 O95831 1 +Gait imbalance 0.3841412702506998 0.6759666649845585 0.4990618098750476 1.0 0.7677382210794117 20 Q05086,Q9NR77 2 +Abnormality of coordination 0.2578044248827951 0.675883549488123 0.4991145830196175 1.0 0.7677382210794117 315 Q9P0J0,Q8NBM4,Q99720,Q5JRX3,O75380,O15118,Q6P4A7,Q9NZ08,P03886,Q14108,P50897,Q8NC96,P04114,O96000,O14653,Q8NHS3,P20700,P41440,Q6DKK2,Q9NR77,P07437,Q96TA2,Q5XKP0,Q9Y487,O96011,Q9Y375,O95470,O43681,O14773,Q96IX5,Q8N0X7,O95831,Q92974,Q9Y2B2,P00846,O75381,Q96F07,O75503,Q9NR45,Q96CU9,Q9UP83,Q96RR1,Q96D71,Q92643,Q12824,Q03252,O60762,Q86VD7,Q96RL7,O95319,O75787,Q8IY17,Q7KZN9,O43819,Q9Y619,Q9H6K4,Q05086,P57740,Q10713,O43678,O96028,P07196 62 +Frequent falls 0.3454643424674401 0.674882824252998 0.4997502136668887 1.0 0.7683829133097698 38 P00846,O43819,Q9NR77,Q96RR1,O43681,Q92974 6 +Abnormal reflex 0.2621290942659964 0.6744530907120502 0.5000232993384324 1.0 0.7683829133097698 350 Q9P0J0,Q9Y3B2,Q99720,Q9BQP7,Q5JRX3,P61978,Q9NZ08,Q8TD30,P03886,Q9NQT5,Q8NC96,Q96AY3,Q08J23,P04114,O14653,O75648,Q13045,P20700,P41440,Q16625,Q9NR77,Q6DKK2,Q96AX1,Q5XKP0,O96011,Q9UNW1,P13073,O14773,O43681,Q96IX5,Q8N0X7,O95831,Q8WXH0,Q5KU26,O95817,Q92974,Q9Y2B2,Q8WWY3,Q9BRK0,P54802,P50570,P00846,Q86XL3,O43464,Q96F07,O75503,Q96CU9,P49902,Q96RR1,O60762,Q96RL7,P83436,Q9BXW9,Q8IY17,Q71SY5,Q7KZN9,O43819,P50416,Q9Y619,Q9H6K4,Q05086,Q10713,Q9BQT8,P07196 64 +Lissencephaly 0.325535608802455 0.6732292454852539 0.5008014581721207 1.0 0.7689326178170175 49 O00459,Q86XL3,Q16625,Q15392,P23786,Q9Y487,P57740,Q9H267 8 +Paraplegia paraparesis 0.3137080360157563 0.6716343451930872 0.5018165078460566 1.0 0.7694139385667867 82 Q8IY17,Q9BRK0,Q7KZN9,P00846,Q6DKK2,Q9Y619,Q9H6K4,Q96CU9,O95831 9 +Poor head control 0.3142120416004809 0.671499355575564 0.5019024698597914 1.0 0.7694139385667867 75 Q9P0J0,Q96F07,Q9NWM8,Q96CU9,Q5XKP0,Q9Y375,P03886,P13073,Q10713,Q8NC96,O96000,Q5KU26 12 +Spastic gait 0.3661177253508644 0.6688967525388884 0.5035613419176657 1.0 0.770652999623995 26 O75787,Q9BRK0,P20700,Q9Y619,O75298,P49902,O00400,Q8N0X7 8 +Bilateral coxa valga 0.3600776447751472 0.6685490471981367 0.5037831846871299 1.0 0.7707321265223568 2 Q96A33 1 +Bradycardia 0.4355559047123915 0.6667414465889159 0.5049372996907493 1.0 0.7722369910867976 12 O43464,O43772,Q96RR1 3 +Areflexia 0.3131449857258812 0.6628110572230844 0.5074515710707668 1.0 0.7746062017525498 81 Q96RL7,Q8IY17,P50570,O43819,P41440,Q9NR77,Q9H6K4,Q96RR1,Q9BQT8,O95831,O14653 11 +Delayed ability to walk 0.3122272931981234 0.6627160824887878 0.5075124076824653 1.0 0.7746062017525498 68 P49366,Q9UBB6,Q99720,P48449,Q05086,Q10713,Q86VD7 7 +Motor delay 0.278872256695809 0.6618191815702232 0.5080871115054317 1.0 0.7749611498719211 226 Q13614,Q99720,Q9NWM8,P61457,Q4J6C6,P61978,P03886,Q08J23,Q03164,P49366,Q5BJH7,O75648,P20700,Q9NR77,P07437,Q96AX1,Q5XKP0,Q9Y487,Q8NCH0,Q8N0X7,Q5KU26,Q92974,Q96J02,P50570,P51970,P48449,Q9UP83,P49902,Q9NSD9,Q96D71,Q03252,Q86VD7,Q71SY5,O43819,Q9UBB6,Q05086,Q10713,Q9NUQ7,P07196 39 +Telangiectasia 0.3542642030765466 0.656561198301202 0.5114631051257588 1.0 0.7778025461564193 33 P03886,P00846 2 +Aplastic clavicle 0.4401125662792073 0.6519600011298347 0.5144269761753142 1.0 0.7809964406847149 5 Q9Y619 1 +Distal lower limb muscle weakness 0.3987967512063058 0.6516227236090056 0.5146445849306307 1.0 0.7809964406847149 17 Q9NR77,P00846 2 +Abnormal blood ion concentration 0.3095437370488907 0.6494686818566848 0.5160354830149592 1.0 0.7823863925927874 64 P49748,Q13423,P61457,Q4J6C6,Q9Y487,Q9NSD9 6 +Rhizomelia 0.4319915980670942 0.6485359693990393 0.516638354217362 1.0 0.7826340453142331 12 O75718,Q03164 2 +Minicore myopathy 0.3846061337883162 0.6479276387046152 0.517031753484055 1.0 0.7828054289046688 3 P51114 1 +Abnormal cerebral artery morphology 0.4088900787938341 0.6462142662117566 0.5181406016783541 1.0 0.7829142513685604 15 P38435,Q9NSD9 2 +Broad palm 0.4518363068155377 0.6436687564521275 0.5197902541485027 1.0 0.7842664675247224 9 O95831 1 +Motor deterioration 0.4382412946010822 0.6432823271133001 0.5200409216298598 1.0 0.7842664675247224 5 O75503 1 +Increased hepatocellular lipid droplets 0.3552248463280485 0.6417122732071558 0.5210600188433681 1.0 0.784969034040724 2 Q9Y6B6 1 +Bradykinesia 0.362119292021085 0.6411061276908592 0.5214537332697178 1.0 0.7853010012339833 26 Q96RL7,O75787,Q5JPH6,Q96IX5,O43464,Q6DKK2,Q14203,Q06787,Q96RR1,P19525 10 +Impaired smooth pursuit 0.4023536166860095 0.6395562723763941 0.5224611185539048 1.0 0.785990731742154 16 P41440 1 +Neurofibromas 0.4635287018279648 0.6392263576858618 0.5226756877170513 1.0 0.785990731742154 6 Q969G3,P21912,Q12824,Q99496 4 +Abnormal synaptic transmission at the neuromuscular junction 0.363152682670872 0.6367175003412998 0.5243088722483455 1.0 0.7862921970886082 24 Q9UNW1,Q15165 2 +Tapered finger 0.3454848141378639 0.6364855208719272 0.5244600153041918 1.0 0.7862921970886082 36 P23786,P42892,Q03164 3 +Hypergalactosemia 0.3539307667421486 0.6345928701335884 0.5256939794593904 1.0 0.7872375956862938 2 Q9UJS0 1 +Hand apraxia 0.3536072468456803 0.6328155511246641 0.526854100226676 1.0 0.7887141685481964 2 Q14683 1 +Pituitary hypothyroidism 0.4617017899159401 0.6311702066248636 0.5279292402042493 1.0 0.7892820537163423 6 Q12824,Q99496 2 +Abnormal esophagus physiology 0.2784182024556175 0.6291366334676758 0.5292596091396233 1.0 0.7893795849895566 221 Q86U42,Q99720,P29372,Q9BQP7,O15118,P03886,Q14108,Q9BUF5,Q69YQ0,Q8NC96,Q92734,Q03164,P49748,Q13045,P20700,Q9NR77,Q96PU5,Q8N0X7,P18887,Q96J02,P00846,Q8NFF5,Q96F07,Q8IZA0,O43791,O94979,P51571,P21912,Q9Y584,Q9NSD9,Q9BPU6,Q96RR1,Q96D71,Q96RL7,P83436,O95319,P48735,Q92766,O43819,P35670,Q9Y619,Q05086,Q9UQE7,Q9UEY8,P21964,O96028 46 +Abnormal circulating lipid concentration 0.3103157589001854 0.6261620578267492 0.5312086511214709 1.0 0.7903831670412161 78 P23786,P50402,O43772,P04114,Q92734,P49748,O75648,Q13045,Q15392,P28070,O96011,O95470,Q8WXH0,P22830,O75381,Q03252,O75844,P50416,P31751,P57740,Q15800 21 +Hypertriglyceridemia 0.3615734114113397 0.6260470984461645 0.5312840493687645 1.0 0.7903831670412161 24 P28070,Q13045,P22830 3 +Short nail 0.4088408935220725 0.6248325654111889 0.5320809548406147 1.0 0.7911100023414566 4 Q9Y487 1 +Muscular hypotonia of the trunk 0.3101101911519621 0.6238249296997467 0.532742565605762 1.0 0.7913270042794778 76 Q5BJH7,Q16625,P61457,Q5XKP0,Q96PU5,Q9NSD9,Q8NC96,Q08J23,P49366 9 +Dilated third ventricle 0.4340110857834814 0.6237497997738498 0.5327919123735998 1.0 0.7913270042794778 5 O75787,Q71SY5 2 +Abnormality of vitamin metabolism 0.3610810217006737 0.6227260704987969 0.5334645476525701 1.0 0.7915474617969678 24 P41440 1 +Abnormal peripheral nervous system morphology 0.2850869221293789 0.6214948980145915 0.5342740503577019 1.0 0.7919703691493422 150 Q13614,Q86U42,Q99720,Q9BQP7,Q9BZK7,P03886,Q9BUF5,P20700,P41440,Q6DKK2,Q9NR77,Q96TA2,O96011,O43681,O95831,O95817,P50570,P00846,O75381,Q96RR1,Q96RL7,Q8IY17,Q71SY5,O43819,Q9Y619,Q9BQT8,P07196 27 +Bruising susceptibility 0.354436790708389 0.6208281574154328 0.5347126946768315 1.0 0.7923613041825471 30 Q13126,Q9NWM8,Q9BZK7,Q14108,Q8NCH0,P38435 6 +Skin appendage neoplasm 0.4075752670767155 0.6187213539064653 0.5360999400483091 1.0 0.7933788724007971 4 P35222,Q14145,P43246 3 +Mask like facies 0.425211506540101 0.6141564216198354 0.5391119672428433 1.0 0.7948364160203208 12 O75787,Q86U42,Q14203,Q05086,Q06787 5 +Diaphragmatic weakness 0.4314567774620612 0.6120145423631534 0.5405281360821264 1.0 0.7959202366916083 5 Q9NR77 1 +Polydactyly 0.3268257596953534 0.6110666140870009 0.541155481017694 1.0 0.7959202366916083 42 O00459,Q9BXW9,Q92766,Q13045,Q8IY17,P61978,Q10713,P21964,Q9Y2V7,O96028 10 +Hemolytic anemia 0.3513351487454079 0.6091300598468948 0.5424382343232985 1.0 0.7961909895344148 31 P41440,P22830 2 +Abnormally folded helix 0.3914318895272568 0.6089972221611846 0.5425262801434245 1.0 0.7961909895344148 17 P23786,Q9Y2B2,Q92766,P21964 4 +Multiple rows of eyelashes 0.3770226537216866 0.6089314361493634 0.5425698862456376 1.0 0.7961909895344148 3 Q9Y2Z4,Q9Y606 2 +Absent forearm bone 0.405317704039928 0.6078515230126712 0.5432859537257098 1.0 0.79672559740287 4 Q9BXW9 1 +Metaphyseal irregularity 0.4390312981973008 0.606013578558374 0.5445057365141073 1.0 0.7976638784064832 10 Q96HY6,Q9NR45 2 +Furrowed tongue 0.4481603182540769 0.605903530687968 0.5445788147958122 1.0 0.7976638784064832 8 P61978,Q71SY5 2 +Proximal tubulopathy 0.3578233583281758 0.6056435614853658 0.5447514690429918 1.0 0.7976638784064832 25 Q9Y2V7,Q9Y375,P03886,Q96CU9 4 +Dilatation of the cerebral artery 0.4389360385292152 0.6055611758118086 0.5448061897990417 1.0 0.7976638784064832 10 Q9NSD9 1 +Left ventricular hypertrophy 0.3590540585258351 0.6051149936738102 0.5451025924370358 1.0 0.7978399818222204 23 O75787,P00403,P21912,Q96RR1,P03886 5 +Narrow palpebral fissure 0.3846851362306187 0.6034254081440297 0.5462257237328865 1.0 0.7988674601907416 18 Q8WXI9,O75648,Q96DF8,Q9BZK7,Q03164,P38159 6 +Abnormal blood transition element cation concentration 0.4147230859312539 0.6032631539522729 0.5463336405454564 1.0 0.7988674601907416 13 P35670,Q9Y487,Q14746,O43819 4 +Central hypoventilation 0.4543485624726051 0.5989535285279097 0.5492038744491436 1.0 0.8015120976980092 6 Q8N183,O43819 2 +Slurred speech 0.4293364118422919 0.5953570557042953 0.5516048248830772 1.0 0.8039800053797747 11 Q96RL7,Q8N0X7,Q9Y487 3 +Paroxysmal involuntary eye movements 0.3574112933932553 0.5913034706211198 0.5543171045815523 1.0 0.8068947569904986 22 Q9Y375,P03886,Q96CU9 3 +Hypopituitarism 0.3415418252651155 0.5891917464710853 0.5557326531730322 1.0 0.8079168545808203 35 Q8IY17,Q4J6C6 2 +Attenuation of retinal blood vessels 0.4480543582410509 0.5873926955283264 0.5569399984488403 1.0 0.8083749416767853 7 P38435,P04439 2 +Lymphoproliferative disorder 0.4006669325349209 0.5855892868106222 0.5581515494079401 1.0 0.8098739650281771 4 P33991 1 +Decreased facial expression 0.3529530741917275 0.5844709714528515 0.5589034898896572 1.0 0.8101864989440472 27 O75787,Q9BUK6,Q86U42,Q9Y5P4,Q14203,Q05086,Q06787,Q96RR1,P19525 9 +Abnormal sternal ossification 0.4251998262819283 0.5834676861796951 0.5595785040700472 1.0 0.8106461859409382 5 Q9Y619 1 +Cleft hard palate 0.3439016499514655 0.5799982694374397 0.5619157848196881 1.0 0.8132519186048521 2 O60315 1 +Abnormal blood inorganic cation concentration 0.3336640921937922 0.5791745920451804 0.5624713730085089 1.0 0.8137960139663192 38 Q9NSD9,P61457,Q4J6C6 3 +Abnormal cortical gyration 0.2796412309211366 0.5753217184493103 0.5650737357445266 1.0 0.8163645581842474 123 P23786,Q9BZK7,Q08J23,P52732,O00459,P20700,Q16625,P07437,Q15392,Q9Y487,O96011,Q5KU26,Q86XL3,O75381,Q9Y2V7,Q12824,Q03252,Q71SY5,Q9UBB6,P57740,Q10713,Q9H267,Q9NUQ7 23 +Polysplenia 0.3699029126213638 0.5727979706779927 0.5667814932753545 1.0 0.8176815810628523 3 P54577,Q9NVR5 2 +Abnormality on pulmonary function testing 0.3848630254837791 0.5714224710846274 0.5677133003824639 1.0 0.8177119811809708 17 Q96J02,O95817,Q9BQT8 3 +Sporadic 0.3526205735939072 0.5704982136196809 0.5683398333793992 1.0 0.8177119811809708 25 Q9BWD1 1 +Hemorrhage of the eye 0.4240975448925501 0.5699603272387411 0.5687046063927148 1.0 0.8177119811809708 11 Q99496,Q9Y487,P50570,O60315 4 +Abnormal pons morphology 0.3607426006019877 0.569692842166206 0.568886045706448 1.0 0.8177119811809708 21 Q9Y3B2,Q9BVA1,P36405,Q9UNW1,Q10713,Q92974,O60762 7 +Type ii diabetes mellitus 0.3389065025928883 0.5689722183515822 0.5693749936915193 1.0 0.8177119811809708 35 Q8IY17,P03886 2 +Falls 0.4309627168327613 0.5679397801881555 0.5700758591486068 1.0 0.8177465617299521 10 Q96RL7,O75787,Q9BQT8 3 +Abnormal iliac wing morphology 0.4307898663465453 0.5671297747275038 0.5706260150835931 1.0 0.8178505712060286 10 O95831,Q9NR45 2 +Abnormality of acid base homeostasis 0.2811934724281785 0.5662639048559182 0.5712143936761196 1.0 0.8180229101147595 182 Q9P0J0,Q9BWD1,Q70HW3,Q4J6C6,P23786,P03886,O96000,P49748,Q5XKP0,Q9Y375,P13073,O95831,P00846,O43464,Q96CU9,Q9Y584,Q96RR1,Q86VD7,P48735,Q7KZN9,O43819,P50416,Q9Y619,Q10713 24 +Hand polydactyly 0.3480607047959848 0.5657797155220187 0.5715435373360815 1.0 0.8180229101147595 29 O00459,Q9BXW9,Q8IY17,Q92766,Q13045,Q10713,P21964,O96028 8 +Neuronal loss in central nervous system 0.4344039002062029 0.5627787265272015 0.5735855680714512 1.0 0.8191496290553827 9 O15118 1 +Nephrotic syndrome 0.3655335395062102 0.5601081851278085 0.57540564776899 1.0 0.8201974777827327 20 Q96AX1,P57740,O95470,Q14108,Q8NCH0 5 +Progressive spastic paraplegia 0.3412961256937341 0.5591738484466008 0.5760430790228894 1.0 0.8204947265187681 33 Q8IY17,Q96CU9,P00846 3 +Underdeveloped supraorbital ridges 0.4141800022223539 0.5590061027879848 0.5761575552000444 1.0 0.8204947265187681 12 O75381,O43791,O96011,Q08J23,P52732 5 +Abnormality of exocrine pancreas physiology 0.3766977296823586 0.5567242791752431 0.57771582587658 1.0 0.8224552769393172 18 Q9UJW0,Q15904,Q9Y3A5,P09601,P40763,Q5HYI8,P42771,P38398 8 +Meningitis 0.4439464434542622 0.5540021585229122 0.5795773684964978 1.0 0.8228302982456155 6 P02786,Q9NZ08 2 +Weakness of the intrinsic hand muscles 0.3390488515043657 0.5539851962684591 0.5795889770790443 1.0 0.8228302982456155 2 Q13586 1 +Hepatitis 0.3814938676526432 0.5523294354798977 0.5807226669145173 1.0 0.8232252816648921 17 Q96J02,Q9Y2V7,Q9Y619,P11717 4 +Prominent nasal tip 0.393613169372053 0.552182951578678 0.5808230135681995 1.0 0.8232252816648921 4 Q71SY5 1 +Aplasia hypoplasia involving the vertebral column 0.4046894770418591 0.5516930409274562 0.5811586786540577 1.0 0.8232252816648921 13 O95831 1 +Abnormal metabolic brain imaging by mrs 0.3912171437773717 0.5496437721414263 0.5825637298187001 1.0 0.8246683986339228 15 P03886 1 +Myalgia 0.3273850032474127 0.5480474553715743 0.5836593184437695 1.0 0.8252112086611347 39 P49748,Q92766,Q8NBM4,P20700,Q13586,Q9BUK6,P50570,O00429,P23786,Q06787,Q9NZ08,Q96RR1,P21964 13 +Slender long bone 0.3899118397877206 0.5426342131179049 0.5873816777807455 1.0 0.8289218069616128 15 Q32P28,Q9Y487,Q9Y619 3 +Abnormal mitochondria in muscle tissue 0.3494136879450938 0.5417397178263241 0.587997824373359 1.0 0.8295329007820978 23 Q9Y375,P03886,Q96CU9 3 +Coma 0.3352352783421866 0.5409866175114763 0.5885168068039524 1.0 0.8300065799570062 35 Q13423,P31751,Q9Y619,P23786,O43772 5 +Abnormal ilium morphology 0.3680614697815859 0.5393733467303254 0.5896292681878001 1.0 0.830535553181448 19 Q9Y2D4,Q99575,Q9NR45,O95831 4 +Abnormal femoral head morphology 0.3680175393781233 0.5391134412112917 0.5898085815860306 1.0 0.830535553181448 19 O95831,Q99575 2 +Abnormality of neuronal migration 0.2792644751529247 0.5368092463974635 0.5913993840453498 1.0 0.8321351465327906 140 P61978,P23786,Q9BZK7,Q08J23,P52732,O00459,P20700,Q16625,P07437,Q15392,Q9Y487,O96011,Q96PU5,Q5KU26,Q86XL3,O75381,Q9Y2V7,Q12824,Q03252,Q71SY5,Q9UBB6,Q9UEY8,P57740,Q10713,Q9H267,Q9NUQ7 26 +Abnormality of retinal pigmentation 0.301319009280092 0.5329680382810724 0.5940557053817157 1.0 0.8339238752337069 71 Q9P0J0,P36405,P03886,P52732,Q8NHS3,Q6P4Q7,Q16836,Q96AX1,Q13432,O96011,Q8WWY3,Q9BUK6,P00846,O75381,P00403,Q96CU9,P21912,Q8IY17,Q7KZN9,O43678 20 +Abnormal gastrointestinal motility 0.3467815405777678 0.5314989452182963 0.595073072042998 1.0 0.8345552311753848 25 Q96RR1,P03886 2 +Abnormal retinal artery morphology 0.3546138057705497 0.5312545827016716 0.5952423734939665 1.0 0.8345552311753848 21 P03886 1 +Abnormal bleeding 0.2958043785941912 0.5308992070770058 0.5954886272756856 1.0 0.8346421663239035 100 Q13126,Q9NWM8,P23786,Q9BZK7,Q9NZ08,Q14108,Q16625,Q9Y487,Q96PU5,Q8NCH0,P50570,Q4KMQ2,Q9Y2V7,Q12824,P38435,Q9BXW9,O75844,Q92766,P21964,Q9H267 20 +Nasogastric tube feeding in infancy 0.4154034722089877 0.5283382564009783 0.5972645835032255 1.0 0.8363550427417656 11 O75648,Q8TD30,P61978 3 +Gynecomastia 0.3600712806979272 0.5268667272668432 0.598286141055858 1.0 0.8374921616693731 20 Q8IY17 1 +Abnormal glial cell morphology 0.3038189090893236 0.5266360022335861 0.5984463857226845 1.0 0.8374921616693731 53 P48735,Q7KZN9,O43819,P00846,O95831 5 +Acanthocytosis 0.4371171079310147 0.5249306091917334 0.5996314299833245 1.0 0.8386324105663662 6 Q96RL7 1 +Unexplained fevers 0.4367840484308195 0.5235224022779926 0.6006107655558228 1.0 0.8394837297031401 6 Q9HC07 1 +Abnormal renal physiology 0.2790304292237365 0.5209706524560516 0.6023872156802428 1.0 0.8404967680414244 151 Q9UBQ7,Q8NBM4,O75380,P23786,Q9BZK7,O43772,Q9NZ08,P03886,Q14108,O96000,Q16625,Q96AX1,Q9Y375,P38398,O43676,O95470,Q8NCH0,Q6W2J9,P09601,P00403,Q96CU9,P21912,Q9Y2V7,Q03252,Q9BXW9,Q8IY17,O43819,P35670,Q8N183,P50416,Q14C86,Q8N1F7,Q9UQE7,P57740,Q10713,Q9H267 36 +Hypoplasia of the brainstem 0.3456960204493035 0.5205297818797877 0.6026943759312431 1.0 0.8404967680414244 24 Q10713,Q9UNW1 2 +Areflexia of lower limbs 0.3463487556301438 0.5197939556149991 0.6032071926375295 1.0 0.8404967680414244 22 Q9H6K4,Q9NR77,Q96RR1,P50570 4 +Abnormality of muscle size 0.277598589844096 0.5182209453182807 0.6043041226444503 1.0 0.8412167301455862 191 Q13614,Q13126,Q99720,Q9BQP7,Q9NWM8,P61978,Q15165,Q96B26,Q6P4A7,Q9NQT5,O00459,O75648,Q6DKK2,Q9NR77,Q96AX1,Q9Y487,Q9UNW1,Q8N0X7,Q99575,O95831,O95817,Q8WXH0,P50570,P51970,Q92804,Q99567,Q12824,Q96RL7,P83436,Q8IY17,Q71SY5,O43819,P50416,Q05086,Q10713,Q9BQT8,P55263,P07196 38 +Large basal ganglia 0.3749063941619308 0.5153816028184527 0.6062863856694125 1.0 0.8421039702840513 17 Q9UBB6,Q08J23,Q9NUQ7 3 +Abnormal circulating carboxylic acid concentration 0.2972068917899915 0.5152344239801431 0.6063892165709879 1.0 0.8421039702840513 93 P48735,P00846,P41440,Q9Y619,P61457,P23786,Q9NSD9,P03886,P55263 9 +Chronic lung disease 0.4193521446333924 0.5141048663681466 0.6071786752764741 1.0 0.8424255433391814 10 Q9UNW1 1 +Arteriovenous malformation 0.4343361956085601 0.5132010419742276 0.607810697167118 1.0 0.8427063858477268 6 Q9BXW9,Q92990,P38398 3 +Increased susceptibility to fractures 0.3069309969312864 0.5130173612756797 0.6079391763687354 1.0 0.8427063858477268 50 P48735,Q13126,Q32P28,Q9UNW1,Q14108,Q96AY3 6 +Increased circulating lactate dehydrogenase concentration 0.4044812374157345 0.5114395563339065 0.6090433024855528 1.0 0.8437205383056741 12 P41440,P23786 2 +Hypoglycemic coma 0.4225301281801628 0.5090538391700856 0.6107144865610334 1.0 0.844160725125646 9 P31751 1 +Patellar dislocation 0.3683549995595892 0.5087501423338553 0.6109273706812215 1.0 0.844160725125646 18 Q9Y2D4,Q92766,Q96PU5,P21964 4 +Petechiae 0.4038238395525191 0.5082498185265688 0.6112781572695023 1.0 0.8442347720825748 12 Q16625 1 +Photophobia 0.3325670683570077 0.5072421604036385 0.611984916352581 1.0 0.8449532676248681 34 Q8WWY3,Q8IY17,Q8NBM4,P48449,P36405,Q13432,Q9NZ08,P04439 8 +Abnormal morphology of the abdominal musculature 0.4168508061531287 0.502668981648988 0.6151970212927407 1.0 0.8462273453765333 10 Q69YQ0,Q8NCH0 2 +Abnormal renal pelvis morphology 0.3028794904387106 0.5024711011239632 0.615336175644658 1.0 0.8462273453765333 52 P83436,Q9Y2B2,P20700,Q71SY5,Q8NCH0,Q6W2J9,O75718,O75381,P61978,Q8N0X7,P36405,P23786,O96011,P98175,Q08J23,O43505 16 +Decreased absent ankle reflexes 0.3865993777926702 0.5013693243806171 0.6161112244767168 1.0 0.8466335556666199 14 Q96RL7,P07196,Q96RR1,Q9H6K4 4 +Decreased cd4 cd8 ratio 0.3826589409748182 0.5012541957221931 0.616192236872593 1.0 0.8466335556666199 4 Q13432 1 +Disproportionate short limb short stature 0.3557201887620153 0.5006814198597315 0.616595350606433 1.0 0.8469305452538332 20 Q32P28,O75718,Q03164 3 +Excessive salivation 0.3315441797086076 0.4996778378215077 0.617301939984475 1.0 0.8471970529273775 34 Q96RL7,O75787,Q9H5V9,P35670,Q9Y5P4,Q9NR77,Q05086,Q8TD30,Q8N0X7,Q03252 10 +Focal dystonia 0.3486426550226985 0.4943202793926183 0.6210800053440346 1.0 0.850946169767809 21 Q99720 1 +Hypotension 0.3416358738427947 0.4941369152563448 0.6212094886141599 1.0 0.850946169767809 24 Q13423,O43772,P20700,P49366 4 +Macrogyria 0.4050718424528098 0.4938242286868986 0.6214303204647345 1.0 0.8509913396932428 5 Q15392 1 +Abnormal macular morphology 0.3420931671397785 0.4927676017995762 0.6221768051591081 1.0 0.851142337127728 22 Q8WWY3,Q8NHS3,P50897,P04439,O60762 5 +Lack of peer relationships 0.3537216828479015 0.4926864073069142 0.6222341834553258 1.0 0.851142337127728 3 P11166,Q96CW1 2 +Frontotemporal dementia 0.4256798260471215 0.4902917209372961 0.6239274846381222 1.0 0.8520927058820299 7 P35637,Q14203,O96008,P22626,P09651 5 +Telecanthus 0.3151221373998489 0.4891152472758118 0.6247601074003177 1.0 0.8521184451963626 41 O00459,O75844,Q92766,Q9Y3B2,Q86XL3,Q8NCH0,P29372,Q96AX1,P36405,Q9BZK7,P21964,Q69YQ0,Q08J23,Q03164 14 +Delayed gross motor development 0.2872816701137968 0.4887740639058932 0.6250016619388428 1.0 0.8521184451963626 109 P49366,Q5BJH7,P50570,Q9UBB6,Q99720,P48449,Q05086,Q10713,Q8NCH0,Q03164,Q5KU26,Q86VD7 12 +Abnormality of the calf 0.2907834941549176 0.4885784933015316 0.6251401422081169 1.0 0.8521184451963626 58 Q96HY6,Q13126,Q32P28,O75718,Q9NR77,Q9Y619,Q9NUQ7,O95831 8 +Protruding tongue 0.3918868865017963 0.4873553461473395 0.6260065322424659 1.0 0.8526186383218192 13 Q96RL7,P83436,Q05086,Q10713 4 +Palpebral edema 0.3790870831984315 0.4849221148349123 0.6277315945299706 1.0 0.8537874487821191 4 Q12756,A6NHR9,Q01082 3 +Upgaze palsy 0.4273732668824272 0.4841256583964352 0.6282966926418729 1.0 0.8541968840539269 6 Q96RR1 1 +Micromelia 0.3405631862222381 0.4831232069226697 0.6290082571455464 1.0 0.854651291202557 22 Q96HY6,O75718,P48735 3 +Bilateral cryptorchidism 0.4053636817316122 0.4811811734829327 0.6303877400864162 1.0 0.8549610289841313 11 P48449 1 +Retinal coloboma 0.4117663581085465 0.4796152281494208 0.6315010161105747 1.0 0.8549610289841313 10 Q9Y2B2,Q10713,O60315 3 +Noncompaction cardiomyopathy 0.3770302186604759 0.4755827912948157 0.6343716377031754 1.0 0.8566228588069003 4 P21912,Q96DA6 2 +Decerebrate rigidity 0.3764972483004077 0.4731708178976758 0.6360913156491124 1.0 0.8575873987769298 4 P16278,O43681,Q9NZJ7 3 +Abnormal heart rate variability 0.3764972483004073 0.4731708178976743 0.6360913156491135 1.0 0.8575873987769298 4 Q8N3U4,Q14683,Q9NZJ7 3 +Microretrognathia 0.3564236747087612 0.4714450460056631 0.6373229543793655 1.0 0.8584882037140599 19 Q16625 1 +Tongue fasciculations 0.3961363023408861 0.471300359506526 0.6374262589747626 1.0 0.8584882037140599 12 O95831 1 +Venous thrombosis 0.388607366798528 0.4711725641495677 0.6375175093364454 1.0 0.8584882037140599 13 P48735,Q9NZ08,P52732 3 +Abnormal left ventricle morphology 0.3368942844992966 0.4705909460621 0.637932874417948 1.0 0.8585530044716939 26 O75787,P00403,P21912,Q96RR1,P03886,O75431 6 +Abnormal muscle glycogen content 0.3989286172251706 0.4672262247290628 0.6403380328919177 1.0 0.860751124332459 5 O75648 1 +Abnormal prolactin level 0.3986122447467953 0.4658671409817322 0.6413106025686843 1.0 0.8607813421144118 5 Q12824,Q99496 2 +Aplasia hypoplasia involving the pelvis 0.3656988320234272 0.4646772502833533 0.6421626023114437 1.0 0.8609572874758384 17 Q96HY6,Q9Y2D4,O95831,Q9NR45,Q99575 5 +Abnormal diaphysis morphology 0.2922463890376285 0.4595666030422139 0.6458273354228916 1.0 0.8634840685146735 65 Q96HY6,Q13126,Q32P28,Q9NR77,Q9Y619,Q9Y487,Q9HC07,Q96AY3,Q9NUQ7 9 +Underdeveloped nasal alae 0.3367619443433091 0.4593361004882037 0.645992827416386 1.0 0.8634840685146735 22 Q08J23,Q5KU26 2 +Lipodystrophy 0.327567393051749 0.4589551358643635 0.6462663838155422 1.0 0.8635949022667865 33 O75844,P31751,Q9Y487,P50402,P28070,Q03252,Q8WXH0,O95817 8 +Ectrodactyly 0.3643177637621369 0.4571747056739982 0.6475454775692391 1.0 0.8648633722651068 17 Q99720,Q9NR77 2 +Constriction of peripheral visual field 0.3483707879785531 0.4571023596402787 0.6475974743318416 1.0 0.8648633722651068 20 Q8WWY3,P00846,Q9H061,O75381,O96011 5 +Ovarian carcinoma 0.3963724702110917 0.4562764090563523 0.6481912258866362 1.0 0.8651462148693171 5 P42771,P38398 2 +Exaggerated cupid s bow 0.4137411093731688 0.454120888960759 0.6497418191789757 1.0 0.8664499384400235 8 P61978 1 +Atrophy degeneration affecting the central nervous system 0.2454637860838862 0.4537001973326225 0.6500446248776961 1.0 0.866598631752785 298 Q9Y3B2,Q99720,Q5JRX3,Q15165,O15118,Q9BZK7,Q96B26,P03886,P50897,Q8NC96,Q9NQT5,Q08J23,Q5BJH7,Q8NHS3,O75648,P20700,Q16625,Q6DKK2,Q96TA2,Q96AX1,P13073,O14773,O95831,Q5KU26,Q9Y2B2,P00846,O43464,P51970,Q96F07,O75503,Q9NR45,Q92804,Q9UP83,Q9NSD9,Q96RR1,Q9Y2V7,Q96D71,O60762,Q96RL7,P83436,O95319,O75787,Q8IY17,Q71SY5,O43819,Q9H9P8,Q9UBB6,P51572,Q9Y619,Q05086,Q10713,Q9NUQ7,P55263,P07196 54 +Broad based gait 0.3348284911909228 0.4505175406724021 0.6523373093109279 1.0 0.8686325723628757 24 Q9Y5P4,Q05086,Q8TD30,O14773,Q03164 5 +Torsion dystonia 0.3446601941747617 0.4492398391751965 0.6532586512278584 1.0 0.869260933879721 3 P11166,O14656 2 +Axonal regeneration 0.3711286394091133 0.4490648525108436 0.6533848741413797 1.0 0.869260933879721 4 P07196 1 +Blue sclerae 0.3345704472005965 0.4469060001139888 0.6549429315646265 1.0 0.8703113757664294 23 Q8NCH0,Q96AY3,O75718,Q9Y3B2 4 +Abnormality of lower limb joint 0.2748063722159164 0.4457575578746158 0.655772382786385 1.0 0.8709026367699573 167 P23786,Q9NQT5,Q96AY3,O00459,Q9Y2D4,O75718,Q9NR77,Q96AX1,Q9Y487,Q96PU5,P38398,Q8N0X7,O95831,O95817,Q96HY6,Q9Y2D2,Q9Y2B2,Q86XL3,Q6W2J9,Q9NR45,O94979,P21912,Q9Y584,P49902,Q9UP83,Q9BPU6,Q9Y5S9,Q03252,O60762,Q9BXW9,O75844,Q92766,O75787,Q5JTV8,Q9Y619,Q05086,Q9UQE7,Q9Y4R8,P21964,O96028,Q9NUQ7 41 +Abnormal duodenum morphology 0.3828669007069864 0.4431680719551802 0.6576441709207068 1.0 0.8723654741642173 13 Q9BXW9,P38398,P98175,Q8NCH0,O60566 5 +Upper extremity joint dislocation 0.3512109684559692 0.4416764818724125 0.6587233304859037 1.0 0.8732855390989592 19 Q96PU5 1 +Confusion 0.3660681776527436 0.4409665513249428 0.6592372123664823 1.0 0.8737111094266135 16 Q9Y619 1 +Serositis 0.3556946343111237 0.4377796483538418 0.6615460253561902 1.0 0.8754903578333455 18 Q8NBM4,Q14C86,P57740,Q9NZ08,P38398 5 +Abnormal vitreous humor morphology 0.412903423205271 0.4368622912028679 0.6622112206535222 1.0 0.8758589283388192 7 Q6W2J9,P04439,P36405 3 +Increased circulating prolactin concentration 0.4124752613654646 0.4351007286143548 0.6634893145870733 1.0 0.8764295963055446 7 Q12824,Q9BUK6,Q99496 3 +Supraventricular arrhythmia 0.3693327641536368 0.4348529281499457 0.6636691838136786 1.0 0.8764295963055446 15 P50402,Q8WXH0,Q96RR1,P00846 4 +Generalized joint laxity 0.3877531828007196 0.4317991089220759 0.6658874272231836 1.0 0.8781618721228301 12 Q9Y487 1 +Abnormal 2nd finger morphology 0.4107905602032533 0.4281886693071902 0.6685137649441146 1.0 0.879154254063086 7 Q9H6K4 1 +Gray matter heterotopia 0.330336648515944 0.4279730247156552 0.6686707599009767 1.0 0.879154254063086 26 Q86XL3,Q9BSJ2,P61978,Q9BVA1,Q06787,Q9UEY8,Q96PU5,O43505 8 +Tongue atrophy 0.3663369050333592 0.4278532758561361 0.6687579464903215 1.0 0.879154254063086 4 P07196 1 +Varicose veins 0.3896493618978592 0.4278253639362268 0.6687782692056059 1.0 0.879154254063086 5 Q92766 1 +Delayed cranial suture closure 0.3275761027886101 0.4249335920371385 0.6708850857485507 1.0 0.8808817138671056 29 O75844,Q32P28,Q8NCH0,O75718,O75381,Q9Y487,Q08J23 7 +Abnormal size of the clitoris 0.3578941765851308 0.4226607283580912 0.6725428121457655 1.0 0.8825663206895474 17 Q9UNW1 1 +Epistaxis 0.3661102107614228 0.4184974033005104 0.6755834846981195 1.0 0.8839957208788218 15 Q13586,P12814,Q6W2J9,Q9Y3A5,Q9BZK7,P35579,P38435 7 +Upper motor neuron dysfunction 0.2528604447002013 0.4139859087071129 0.6788844266977567 1.0 0.8870338773985688 366 Q9P0J0,Q99720,Q15165,O15118,Q96B26,Q9NZ08,Q8TD30,P03886,P50897,Q8NC96,Q9NQT5,Q08J23,P52732,P49366,Q5BJH7,Q8WXI9,P20700,P41440,Q16625,Q9NR77,Q6DKK2,Q5XKP0,Q15392,Q9Y487,O96011,Q9UNW1,O43681,O14773,Q8N0X7,O95831,Q5KU26,Q9BRK0,Q86XL3,P00846,O43464,P51970,Q96F07,O75381,O75503,Q96CU9,Q92804,P49902,Q96D71,Q12824,O60762,O95319,O75787,Q8IY17,Q13423,Q7KZN9,O43819,P50416,Q9UBB6,Q71SY5,P51572,Q9Y619,Q9H9P8,Q9H6K4,Q9UEY8,P57740,Q10713,Q9NUQ7,P07196 63 +Proximal muscle weakness 0.2867206826895566 0.4134522054244685 0.6792753326276297 1.0 0.8871185558544729 63 Q13614,Q9BUK6,Q13126,P50570,Q86U42,P00846,Q99720,Q8NFF5,P21912,P50402,P51114,Q96RR1,Q9BQT8,Q92734,Q8WXH0,P07196 16 +Paranoia 0.3861335649516816 0.4131579341479058 0.6794909057474943 1.0 0.8871185558544729 5 Q96RL7 1 +Aplasia hypoplasia of the vagina 0.3365695792880298 0.4114377812456522 0.6807515551245626 1.0 0.8876812160950688 3 P30153,P51809 2 +Abnormality of the clitoris 0.3400519080959744 0.4088688411813352 0.6826359164362361 1.0 0.8888590691164557 20 Q9UNW1 1 +Myopathic facies 0.4055695626242714 0.4069673530382957 0.684031966334691 1.0 0.8897229505549387 7 Q9Y5P4 1 +Weakness due to upper motor neuron dysfunction 0.270756895173481 0.4066422783837686 0.684270740556502 1.0 0.8897229505549387 136 Q9P0J0,Q8NBM4,Q96B26,Q9NZ08,Q9Y3Z3,P03886,Q8TD30,Q92734,P20700,Q6DKK2,Q5XKP0,O43681,Q8N0X7,O95831,Q9BRK0,P00846,Q6W2J9,P51970,P00403,O43791,Q96CU9,P21912,P49902,Q12824,O75787,Q8IY17,Q13423,Q7KZN9,Q9H9P8,P50416,Q8N183,P51572,Q9Y619,Q9H6K4,P57740,O43678 36 +Distal sensory impairment 0.3010759478605367 0.4060294656661186 0.6847209503065566 1.0 0.8897229505549387 44 Q13614,P54802,Q71SY5,P50570,Q9NR77,Q96RR1,O95831,O95817,P07196 9 +Status epilepticus 0.302089151997442 0.4036141136343474 0.6864965054817032 1.0 0.8898599478424049 42 P51970,Q96F07,Q15392,Q9Y487,Q96RR1,Q8NC96,P42892,Q03252,P52732 9 +Tachypnea 0.3492330049002659 0.402531737511519 0.6872927359937728 1.0 0.8898599478424049 18 P49748,Q9Y619,Q9NSD9 3 +Waddling gait 0.3268192171029661 0.4024765758834843 0.6873333239515618 1.0 0.8898599478424049 25 P07196,Q9NUQ7,Q8WXH0,Q4J6C6 4 +Sensory axonal neuropathy 0.3628074452446732 0.4018997395916001 0.6877578143903236 1.0 0.8899008566661427 15 O95831 1 +Abnormality of the intrinsic pathway 0.3932601708223353 0.3981156841454487 0.6905449136560715 1.0 0.8914700652214317 10 Q9Y487,P38435 2 +Central nervous system cyst 0.29160685524142 0.3976874369945138 0.6908605991038308 1.0 0.891623508245115 52 P00846,O60566,Q6W2J9,P07437,Q9BSJ2,P23786,Q9Y487,O96028,Q9BPU6,Q99567,Q9NQT5,Q12824 12 +Duplicated collecting system 0.4056314479193731 0.3963717965978924 0.6918307689428989 1.0 0.892113117936616 6 Q9Y2B2,Q9BXW9 2 +Hypoplastic nipples 0.3920667568078456 0.3930024391709233 0.6943176798461748 1.0 0.8937689044606146 10 Q9Y2B2,P07437 2 +Abnormality of the distal phalanges of the toes 0.4044355815373355 0.391692914900347 0.695285125677529 1.0 0.8937689044606146 6 O75844,Q71SY5,O75431 3 +Progressive 0.2847674039245964 0.3856673684040421 0.6997430328714977 1.0 0.8976036124870868 100 Q96RL7,O60762,Q8IY17,P54802,Q13126,P20700,Q86U42,Q99720,Q9BQP7,Q5XKP0,P57740,Q96RR1,Q8TD30,O95470,Q96D71,O95831,P55263,O14653 18 +Generalized hypotonia 0.2494936696972096 0.380558638469411 0.7035307775148181 1.0 0.9007038450379774 347 Q9P0J0,Q9BWD1,Q70HW3,P61457,Q4J6C6,P61978,O15118,P23786,Q6P4A7,O43772,Q9HC07,Q8TD30,P50897,Q8NC96,Q9NQT5,Q08J23,Q03164,Q5BJH7,O75648,Q9NR77,P07437,Q13555,Q96TA2,Q5XKP0,Q9Y487,O95470,O43681,P13073,Q8NCH0,O95831,Q8N0X7,Q5KU26,Q92974,Q96J02,Q9Y2B2,P50570,O43464,O75381,Q96F07,Q9NR45,P51571,Q96CU9,Q9NSD9,Q96RR1,Q9Y2V7,Q96D71,Q92643,Q12824,O60762,Q86VD7,P83436,Q71SY5,Q7KZN9,O43819,P50416,Q9UBB6,Q9Y619,Q05086,Q10713,Q9H267,Q9NUQ7,P55263 62 +Bilateral sensorineural hearing impairment 0.323815416871782 0.3803812214607991 0.7036624520064905 1.0 0.9007038450379774 22 P00403,Q96RR1,P03886,O43681,Q96DA6,P38159 6 +Abnormal branching pattern of the aortic arch 0.3550192020127931 0.3789876022539838 0.7046970703008482 1.0 0.9012783487151156 4 O00459 1 +Thoracolumbar scoliosis 0.3947231044182617 0.375324653089882 0.7074190335452915 1.0 0.9032153951409724 8 Q99575 1 +Repetitive compulsive behavior 0.3538361929426898 0.3739862901609592 0.7084145161736868 1.0 0.9041850285605024 4 Q96DA6,Q9H7D7,Q01082 3 +Abnormal palate morphology 0.2487275479923084 0.3737670023190712 0.7085776713884733 1.0 0.9041850285605024 273 P29372,Q9NWM8,P61978,P23786,Q9BZK7,Q9BUF5,Q69YQ0,Q08J23,Q03164,P49366,Q8WXI9,O75648,Q13045,Q9Y2D4,Q16625,P07437,Q15392,Q9Y487,P46783,Q96PU5,Q9UNW1,P38398,O96011,Q8NCH0,O95831,Q5KU26,Q92974,Q9Y2B2,Q9BUK6,Q96DF8,Q6W2J9,P51970,O75381,O43791,O94979,P21912,Q9UP83,Q9NSD9,Q9BPU6,Q03001,Q96RR1,Q99567,O60762,Q9BXW9,O75844,Q92766,Q71SY5,Q9UBB6,Q9Y619,Q9UQE7,P57740,Q10713,P21964,O96028,P07196,P78318 56 +Supernumerary nipple 0.3678782669478923 0.3721813899375356 0.7097578011206815 1.0 0.9049262142067794 13 Q9Y2B2,Q8IY17,P61978,O60315,Q7LGA3 5 +Supernumerary tooth 0.3938411669367848 0.3717765408140301 0.7100592314560328 1.0 0.9050558014901036 8 Q9Y2B2,Q9UHX1,Q6W2J9,P21281,O60488,Q6DKJ4,Q9UBM7 7 +Abnormal pericardium morphology 0.3898327180627452 0.3685496448580138 0.7124634347696066 1.0 0.9059585052293202 9 P49748,Q9NZ08 2 +Gastroesophageal reflux 0.2671083971200749 0.3680935309283441 0.7128034943599211 1.0 0.9059585052293202 127 P49748,Q13045,P00846,Q96F07,Q9Y619,Q8IZA0,Q9Y584,Q96PU5,Q9NSD9,Q8NC96,Q03164 11 +Hypogonadotropic hypogonadism 0.3213844745892988 0.3670359344810944 0.713592213904239 1.0 0.9059585052293202 24 P03886 1 +Skeletal dysplasia 0.3042774455948977 0.3668012060118222 0.7137673079831002 1.0 0.9059585052293202 39 Q96HY6,Q9Y2D4,Q96AX1,Q99575,Q9NR45,Q9NUQ7,O96011,Q9HC07,O95831 9 +Constipation 0.2840207550425084 0.3664546227733354 0.7140258669152955 1.0 0.9060328227244504 98 P78318,Q8WXI9,Q13045,Q13423,Q92766,Q8NCH0,O43464,P61978,Q05086,Q96RR1,P03886,P42892,Q03164,P49366 14 +Facial diplegia 0.3852756215689441 0.3642661094377258 0.715659304671854 1.0 0.9068354266191604 10 Q96RR1,O43819 2 +Abnormality of subcutaneous fat tissue 0.3548890898898049 0.3628288671796293 0.7167327263361516 1.0 0.90716808629673 15 Q9Y487,Q9BZK7,O75844 3 +Abnormality of skull ossification 0.3721208079749937 0.3606443427184237 0.7183653363273486 1.0 0.9079748097412468 12 Q32P28,O75718,P54802 3 +Metatarsus adductus 0.3784239088211429 0.3604635877094932 0.71850048178167 1.0 0.9079748097412468 11 Q15392,Q08J23,Q03252 3 +Oral ulcer 0.391008742782622 0.3604498436439927 0.7185107581945387 1.0 0.9079748097412468 8 Q9NZ08 1 +Stomatitis 0.3579740226881768 0.3594760196666279 0.7192390141130198 1.0 0.9085757763335136 14 Q9BZK7 1 +Abnormal circulating glutamine family amino acid concentration 0.3948175246641334 0.3546842692092739 0.7228261370915727 1.0 0.9113944696016932 6 Q9UJS0,O96000 2 +Apnea 0.2865208184179924 0.3528966732257399 0.7241659049692442 1.0 0.9119919745270462 82 Q7KZN9,P00846,O43819,Q96CU9,P23786,O43772,P03886,Q10713 8 +Cutaneous photosensitivity 0.3245807427060007 0.3517852092008832 0.7249993517913349 1.0 0.9119919745270462 21 P22830,Q08J23,Q14108,P14324 4 +Nausea and vomiting 0.2681003673769871 0.3511446453086369 0.725479835683553 1.0 0.9121353471125436 144 P49748,Q13423,P00846,Q9BQP7,P61978,Q9Y619,Q8IZA0,Q15165,Q96CU9,Q92804,P23786,Q9Y584,Q9NZ08,Q9NSD9,P03886,Q9Y375,P42892 17 +Myopathy 0.2832591810194814 0.3491284717106784 0.7269928624877022 1.0 0.9126781141883014 96 Q13126,Q86U42,Q9BQP7,Q9NWM8,P23786,P50402,P03886,O75648,Q9Y375,O43676,Q8NCH0,Q8WXH0,O95817,Q9BUK6,P50570,P00846,Q8NFF5,P00403,P21912,Q96RR1,Q03252,Q96RL7,O14979,P07196 24 +Generalized muscle weakness 0.3159940991523542 0.3490626512469329 0.7270422750940482 1.0 0.9126781141883014 29 O95831,Q15165 2 +Abnormal circulating albumin concentration 0.3165992385847167 0.3482915084088621 0.7276212704127414 1.0 0.9126781141883014 28 Q14C86,Q96AX1,Q5XKP0,P57740,Q9NSD9 5 +Hypertrophic cardiomyopathy 0.278453038680681 0.3481827793262047 0.7277029197253664 1.0 0.9126781141883014 107 Q9P0J0,O75380,P50402,Q9Y3Z3,P03886,O96000,P49748,Q9H061,Q16836,Q96AX1,Q5XKP0,Q9Y375,P38398,O43676,Q96IX5,Q8WXH0,O95817,P54802,P00846,P00403,Q96CU9,P83436,Q9BXW9,Q13423,Q7KZN9,O43819,P50416,O43678 28 +External ear malformation 0.3384399127636806 0.3453383729003966 0.729840001646701 1.0 0.9140655812716494 18 Q9BXW9,O75381,P07437,O96011,P38398,Q8NCH0 6 +Premature rupture of membranes 0.3907081198481795 0.3392252883465689 0.7344400201671522 1.0 0.915741419840472 6 Q9Y487 1 +Female infertility 0.3200647249190982 0.337623987954586 0.7356465628453732 1.0 0.9163074954601076 3 Q86Y56,Q9NVR5 2 +Abnormality of corneal size 0.3003822159846371 0.3375854924232042 0.7356755763771328 1.0 0.9163074954601076 39 Q13045,Q71SY5,P07437,Q9NWM8,Q9UQE7,Q9BZK7,Q8NCH0,P52732 8 +Facial capillary hemangioma 0.3197411003236302 0.3362251163306994 0.7367011142070221 1.0 0.916872247930688 3 P16435,Q9UBM7 2 +Nephronophthisis 0.31941747572816 0.3348282195826132 0.737754671852205 1.0 0.917635547361474 3 Q8TD19,Q9NQH7 2 +Narrow palate 0.2998403622711414 0.3335575782343526 0.7387134341613768 1.0 0.918166635735154 39 P23786,Q9Y619,P61978,O60762 4 +Abnormal social behavior 0.281099336616442 0.3334565132402452 0.7387897102107366 1.0 0.918166635735154 67 Q9P0J0,Q96CU9,Q5XKP0,Q9Y375,P03886,Q96RR1,Q9Y2V7,O96000,Q5KU26 9 +Inappropriate laughter 0.3834511871257645 0.330756432566751 0.7408284720336895 1.0 0.9202134803139076 8 Q05086 1 +Ophthalmoparesis 0.282534198906019 0.3303232586927981 0.7411557204447965 1.0 0.9202134803139076 71 Q9P0J0,P50570,P00846,O43819,Q7KZN9,Q9BQP7,Q96CU9,Q96RR1,P03886,Q10713,Q96IX5 11 +Ectopic calcification 0.2782163715236694 0.329393026540977 0.7418586379925807 1.0 0.9202134803139076 56 O75844,P35670,O75381,Q16625,P00403,Q96AX1,P38435,O00116,P23786,O96011,Q9Y3Z3,P03886,Q9NSD9,P04114,O75431,Q12824 16 +Vascular skin abnormality 0.275066621357369 0.3276766079713598 0.7431561918811171 1.0 0.920945603084808 110 Q9BXW9,P22830,P00846,Q13126,Q8NCH0,Q16625,Q9NWM8,Q8IZA0,Q9BZK7,Q9Y487,P03886,Q14108,Q08J23,P38435,O60762 15 +Aphthous ulcer 0.3874882119856366 0.3272677825536489 0.7434653577221066 1.0 0.920945603084808 6 Q9NZ08 1 +Abnormal electroretinogram 0.311680850094809 0.3216535502634466 0.74771517064706 1.0 0.9249453094022888 29 O14773,Q8IY17,P00846,P50897 4 +Widely spaced incisors 0.3626228614686084 0.3192520518397534 0.7495353887280303 1.0 0.9263828941980782 5 Q8WXI9,Q9BSJ2 2 +Abnormal palmar dermatoglyphics 0.2737406678970099 0.3190411671066993 0.7496952958344711 1.0 0.9263828941980782 58 P61978,P36405,Q9BZK7,P98175,Q69YQ0,Q96AX1,Q9Y487,O96011,Q96S52,Q8NCH0,Q96J02,Q6W2J9,O75381,Q99567,Q8IY17,Q71SY5,Q9UQE7,P57740,Q9Y4R8,O75431,O96028 21 +Periorbital edema 0.3132747118416454 0.3183767327291685 0.7501991853617158 1.0 0.9267266041417768 23 Q14C86,P28070 2 +Thin skin 0.3185344535312486 0.3178652187381134 0.7505871767320482 1.0 0.9267266041417768 21 Q9Y619,Q96PU5 2 +Asymmetry of the ears 0.3152103559870586 0.3168511444467614 0.7513565543873759 1.0 0.9271711226845036 3 Q6W2J9,Q9UHX1 2 +Restrictive behavior 0.3392683716412967 0.3142086035401267 0.7533626086786014 1.0 0.9283065432487532 4 Q14683,Q01082,P51608 3 +High palate 0.2646658732667899 0.3122076335827398 0.7548827311057866 1.0 0.9292288602617096 202 P29372,P61978,P23786,Q69YQ0,Q08J23,Q03164,P49366,Q8WXI9,O75648,Q9Y2D4,Q16625,P07437,Q9Y487,P46783,O96011,Q9UNW1,P38398,Q8NCH0,O95831,Q5KU26,Q92974,Q9Y2B2,Q9BUK6,Q6W2J9,P51970,O75381,O43791,O94979,P21912,Q9UP83,Q9NSD9,Q03001,Q96RR1,Q99567,O60762,Q9BXW9,O75844,Q71SY5,Q9UBB6,Q9Y619,Q9UQE7,P57740,P07196,P78318 44 +Dilated fourth ventricle 0.2969115169204813 0.3119455807718199 0.7550818812018998 1.0 0.9292288602617096 39 O60566,Q6W2J9,P07437,P23786,Q9Y487,Q9BPU6,Q99567,Q10713,Q12824,O43505 10 +Infantile spasms 0.307347274156479 0.3111705109185877 0.7556709998335163 1.0 0.9292288602617096 32 P03886 1 +Abnormality of lower limb epiphysis morphology 0.3401060270090548 0.31049093326764 0.756187653244488 1.0 0.9292288602617096 16 O95831 1 +Abnormal cerebral cortex morphology 0.263088599328483 0.3103351043522385 0.7563061385838683 1.0 0.9292288602617096 212 P23786,Q9BZK7,Q96B26,P03886,Q08J23,P52732,O00459,O75648,P20700,Q16625,P07437,Q15392,Q9Y487,O96011,Q96PU5,Q5KU26,Q9Y2B2,Q86XL3,P00846,P51970,O75381,O75503,Q96RR1,Q9Y2V7,Q12824,Q03252,O60762,Q96RL7,Q71SY5,O43819,Q9UBB6,P51572,Q9Y619,Q9BSJ2,Q05086,P57740,Q10713,Q9H267,Q9NUQ7 39 +Osteoarthritis 0.3663359945048194 0.3096037184486991 0.7568623282384657 1.0 0.9296600723753388 11 Q96HY6,O75844,Q9NUQ7,Q14108 4 +Abnormal retinal morphology 0.2636097826798891 0.308290062315088 0.7578616271675616 1.0 0.9297411635593248 208 Q9P0J0,Q8NBM4,P36405,Q9NZ08,P03886,P50897,Q8NC96,P04114,Q9NQT5,P52732,Q8NHS3,O75648,Q13045,P07437,Q6P4Q7,Q16836,Q96AX1,Q5XKP0,Q9Y487,Q13432,Q9Y375,O96011,O14773,Q8NCH0,Q9Y2B2,Q8WWY3,Q9BUK6,P50570,Q96DF8,P00846,Q6W2J9,Q96F07,O75381,P00403,O75503,Q96CU9,P21912,P38435,O60762,O95319,Q8IY17,Q92766,Q7KZN9,O43819,Q9Y619,Q10713,P21964,O43678,O96028,P04439 50 +Abnormality of female external genitalia 0.3030452304341262 0.3075531619467512 0.7584223649946438 1.0 0.9297411635593248 35 O75381,Q9Y619,Q15392,Q9UQE7,O96011,Q9UNW1,Q08J23 7 +Low frustration tolerance 0.3713700073809786 0.3074842606809742 0.7584748013060625 1.0 0.9297411635593248 10 Q03164 1 +Abnormal tongue physiology 0.3309633390956996 0.3070891517053781 0.7587755147193873 1.0 0.9297411635593248 18 O95831 1 +Nasal speech 0.3052196958419592 0.3045903998708669 0.7606781325972896 1.0 0.9313167407204652 33 O75648,Q92766,Q96DF8,Q9BQP7,Q4J6C6,Q9Y487,P21964,O95817 8 +Intestinal malrotation 0.3088536461596379 0.3039612079190508 0.7611574452623691 1.0 0.9316517770976848 29 Q92766,Q6W2J9,O60826,Q15392,Q9UQE7,Q9NSD9,P21964,Q8NCH0,O96028 9 +Poor suck 0.3100873231687659 0.3000972713405388 0.7641029604966258 1.0 0.9328367942723352 24 O43464,Q05086,O43819 3 +Abnormality of the kidney 0.2421136456595721 0.2999899204752249 0.7641848440495886 1.0 0.9328367942723352 318 Q8WU17,Q9UBQ7,Q8NBM4,Q9BQP7,P61978,Q4J6C6,O75380,P23786,Q9BZK7,O43772,Q9NZ08,P03886,Q92733,Q14108,P04114,P36405,Q08J23,Q03164,O96000,Q69YQ0,O00459,Q13045,P20700,Q16625,O75718,Q96AX1,Q15392,P46783,Q9Y375,Q9UNW1,O96011,O95470,P38398,O43676,Q8NCH0,Q8N0X7,Q9Y2B2,Q86XL3,P00846,O75381,Q6W2J9,P09601,P51571,P00403,Q96CU9,O43791,P21912,Q9Y5S9,Q9Y2V7,Q12824,Q03252,P83436,Q9BXW9,Q8IY17,Q92766,Q71SY5,O43819,P50416,Q14C86,P35670,Q8N183,O60566,Q8N1F7,Q9UQE7,P57740,Q9Y4R8,Q10713,P21964,P35579,Q9H267,O75431,O96028,O43505 73 +Hypokalemia 0.3793326854551314 0.2976189149273685 0.7659940364190381 1.0 0.9335491778900684 6 Q9H3U1,P05023,P04637,Q08426,Q9UNF1 5 +Avascular necrosis 0.3145539003649513 0.2960173866725472 0.7672168034823588 1.0 0.9345232911468364 21 O75844,Q9Y619,Q9NZ08,Q14108,Q9NUQ7 5 +Cerebellar vermis atrophy 0.3712054639461227 0.2946364914678385 0.7682715827945412 1.0 0.9348026511037528 9 Q96S52,P07437,Q10713 3 +Abnormal myocardium morphology 0.2656755972856783 0.2935157356571065 0.7691279735713756 1.0 0.9353422067861292 167 Q9P0J0,Q8NBM4,Q9BQP7,O75380,P23786,P50402,O43772,Q9Y3Z3,P03886,Q9NZ08,Q14108,O96000,P49748,Q9H061,Q16836,Q96AX1,Q5XKP0,O96011,Q9Y375,P38398,O43676,Q96IX5,Q8WXH0,O95817,P54802,P00846,Q8NFF5,O75381,P00403,Q96CU9,Q96RR1,Q96RL7,P83436,Q9BXW9,P48735,Q13423,Q7KZN9,O43819,P50416,P57740,O43678 41 +Lipid accumulation in hepatocytes 0.2806625489024325 0.2927157064007427 0.7697394635137189 1.0 0.9358346134506568 77 P49748,Q7KZN9,P50416,P31751,Q5XKP0,P23786,O43772,Q9NSD9,Q9Y375,P55263 10 +Inability to walk 0.2810143946536701 0.2919446390268909 0.7703289524280104 1.0 0.9363000146227226 85 Q96C86,Q99720,P61978,O00429,Q92734,Q9NR77,Q96AX1,Q96S52,Q9NVI7,Q9BUK6,P00846,O75503,O94979,Q96CU9,P21912,Q96RR1,Q96D71,Q9C0E8,Q96RL7,O75787,Q71SY5,P35637,O60315,Q9Y4R8,P07196 25 +Abnormal form of the vertebral bodies 0.2808236278520803 0.2886974889856589 0.7728128844222848 1.0 0.9376163117128432 83 Q96HY6,Q96J02,P48735,P54802,Q13045,Q32P28,Q9Y619,Q99575,Q9NUQ7,Q10713,Q96AY3,O95831 12 +Abnormal myelination 0.2618883967748669 0.2885656310467795 0.7729137995334987 1.0 0.9376163117128432 212 Q13614,Q9P0J0,Q9Y3B2,Q99720,Q8TD30,P03886,Q8NC96,O96000,Q5BJH7,Q8WXI9,P20700,P41440,Q9NR77,Q96AX1,Q9Y375,O43681,O95831,Q5KU26,O95817,Q9Y2B2,P50570,P00846,Q96F07,Q96CU9,Q9Y584,Q9UP83,O60762,Q96RL7,P83436,O95319,O75787,Q7KZN9,O43819,Q9UBB6,P51572,Q05086,P07196 37 +Aortic regurgitation 0.3080393721201248 0.2884434426037903 0.7730073176971062 1.0 0.9376163117128432 23 Q96PU5 1 +Generalized amyotrophy 0.3077183767784023 0.2883139468546567 0.7731064321791488 1.0 0.9376163117128432 26 Q8IY17,O43819,Q9BQP7,Q99567,O95817 5 +Abnormality of head blood vessel 0.3077494859302512 0.2872125467512252 0.7739495799452356 1.0 0.9376816253415132 25 P03886 1 +Abnormality of femur morphology 0.2764108919353945 0.2859021412636695 0.7749530736819386 1.0 0.9380280375029654 67 Q96HY6,Q32P28,O75718,Q9Y619,Q99575,Q9NR45,Q9NUQ7,Q9Y487,Q96AY3,O95831 10 +Abnormal conjugate eye movement 0.2394998717259127 0.284943849719255 0.7756871606647717 1.0 0.9380280375029654 306 Q9P0J0,Q9Y3B2,Q99720,O75380,O15118,P36405,Q9BZK7,P03886,Q9NQT5,Q08J23,Q03164,O96000,Q8WXI9,O75648,Q13045,P20700,Q9H061,Q96TA2,Q15392,Q9Y487,P46783,Q96PU5,Q9Y375,O96011,O95470,Q8NCH0,Q5KU26,Q92974,Q9Y2B2,O75381,Q9NR45,P51571,Q96CU9,Q9UP83,Q96RR1,P38435,Q12824,O60762,Q96RL7,Q9BXW9,Q8IY17,Q92766,Q7KZN9,O43819,Q71SY5,Q9UBB6,Q9H9P8,P51572,Q9Y619,Q05086,Q9UQE7,Q9UEY8,Q10713,P21964,O43678,O96028 56 +Cerebellar cyst 0.2981313390035395 0.2839946048748969 0.7764145151873083 1.0 0.9380280375029654 36 O60566,Q6W2J9,P07437,P23786,Q9Y487,Q9BPU6,Q99567,Q9NQT5,Q12824,O43505 10 +Emg neuropathic changes 0.3066952409860533 0.2811163650628061 0.7786211495891211 1.0 0.9380280375029654 25 Q96RL7,Q9NR77,O14773 3 +Diffuse alveolar hemorrhage 0.3725011182309345 0.2805471368233045 0.7790577668055749 1.0 0.9380280375029654 7 Q6W2J9,Q9BZK7,Q6UN15 3 +Addictive behavior 0.3725011182309345 0.2805471368233045 0.7790577668055749 1.0 0.9380280375029654 7 Q6W2J9,Q9BZK7,Q6UN15 3 +Metrorrhagia 0.3725011182309345 0.2805471368233045 0.7790577668055749 1.0 0.9380280375029654 7 Q6W2J9,Q9BZK7,Q6UN15 3 +Motor polyneuropathy 0.3642709845404197 0.2796592988802758 0.7797389075381147 1.0 0.9380280375029654 10 P07196,O43819 2 +Angina pectoris 0.3742273984310464 0.2795452729662403 0.7798263993898824 1.0 0.9380280375029654 6 P04114 1 +Retinal degeneration 0.2769026140942392 0.2778497486692199 0.7811277002143682 1.0 0.9385617157515465 53 O95319,P04114,O75648,Q8WWY3,Q8IY17,Q96F07,O75503,Q10713,O14773,Q8NC96,P50897 11 +Abnormal pulmonary interstitial morphology 0.300947879154108 0.2766378435145237 0.7820582033426313 1.0 0.9387185111664336 33 P09601,Q8IZA0,Q13432,Q9NSD9,Q14108 5 +Complete duplication of phalanx of hand 0.3509273135680135 0.2755914227424756 0.7828618983003504 1.0 0.9389368279853288 5 Q9BXW9 1 +Respiratory insufficiency 0.2644049837197147 0.2745418913050143 0.7836682152198085 1.0 0.9390060083464672 178 Q70HW3,Q9BQP7,Q15165,P23786,Q96B26,O43772,P03886,Q96AY3,Q08J23,O96000,P49748,Q9NR77,Q5XKP0,Q9Y375,O95831,O95817,P50570,O43464,Q96CU9,Q92804,Q9NSD9,Q96RR1,P33991,O43819,Q9Y619 25 +Abnormal hypothalamus physiology 0.37235662280309 0.2730198195369487 0.7848379803576595 1.0 0.939317318631492 6 Q969G3,Q12824,Q99496 3 +Corneal dystrophy 0.3500647668393765 0.2724602856230379 0.7852681240012349 1.0 0.939398819045528 5 Q13868,P06280,P12235,Q9Y5Z9 4 +Duplication involving bones of the feet 0.3388727388924457 0.2723221705443232 0.7853743105453395 1.0 0.939398819045528 14 O96028,Q92766,Q10713,P21964 4 +Poor speech 0.2788202816303499 0.2709564272537022 0.786424545007673 1.0 0.9394786890518878 78 Q9P0J0,Q9UBB6,P61978,Q96CU9,Q05086,Q9Y487,Q10713,Q08J23,Q9NUQ7,P55263 10 +Central apnea 0.3672609400324205 0.269947469737496 0.787200666751642 1.0 0.939888762891154 8 Q14683,P07602,P11166,Q8N3U4,Q10713,O76024,Q9NZJ7 7 +Childhood onset 0.29964314694579 0.2682148500852143 0.788533944934958 1.0 0.9401076957763728 33 P22830,Q9NR77,Q5JRX3,Q8N0X7,Q9NUQ7,Q8WXH0 6 +Vertical supranuclear gaze palsy 0.3443483655689826 0.2681143347469709 0.7886113121302907 1.0 0.9401076957763728 13 O15118,Q96RR1 2 +Infectious encephalitis 0.3620026921770895 0.2600984621408473 0.794787824148325 1.0 0.9449839483968274 9 Q9NZ08,Q9H9P8 2 +Extrapyramidal muscular rigidity 0.3679522315175906 0.2578690111745186 0.7965080017081203 1.0 0.9465323315156834 6 O75787,Q9H6K4 2 +Pulmonary infiltrates 0.3677123880970715 0.2570526491353585 0.7971381300487388 1.0 0.9469446200126306 6 Q9NZ08 1 +Macular thickening 0.3676610173306282 0.2568779148567844 0.7972730200282943 1.0 0.9469446200126306 6 Q8WWY3,P04439 2 +Peripheral neuropathy 0.2629763968925304 0.255938059276395 0.7979986660413769 1.0 0.9474945262346806 155 Q96RL7,Q8IY17,Q13045,Q7KZN9,P00846,P41440,P50570,O43819,Q9NR77,Q96CU9,Q96RR1,P03886,Q10713,O95831,Q5KU26 15 +Generalized onset seizure 0.271036226219704 0.2557364738334963 0.7981543293844462 1.0 0.9474945262346806 108 O60762,Q8NHS3,Q8WXI9,P00846,Q9UBB6,Q9Y619,O75503,P61978,Q05086,P03886,Q14108,Q08J23,Q9NUQ7,O14653 14 +Dysuria 0.3670229996760579 0.2547112135382838 0.7989461547006189 1.0 0.948186031122296 6 O00170,P07741,O76024,P00492,Q8N0X7 5 +Postaxial polydactyly 0.323776866523969 0.2520126510923701 0.801031285178921 1.0 0.949168642914076 17 Q10713,P61978,Q9Y2V7 3 +Difficulty walking 0.2766979073775458 0.250342725820857 0.8023223176981604 1.0 0.9504498167292538 77 P50570,P00846,Q99720,Q9NR77,O14773,Q8NC96,O14653 7 +Abnormal size of the palpebral fissures 0.2769658804865892 0.2496695714481212 0.8028428915559775 1.0 0.950657119115034 88 P61978,Q9BZK7,Q08J23,Q03164,O00459,Q8WXI9,O75648,P20700,P07437,Q13555,P38398,Q5KU26,P38159,Q9Y2B2,Q9H5V9,Q96DF8,Q6W2J9,O43791,P83436,Q9BXW9,O75844,Q9Y619 22 +Hypokinesia 0.3447895277928349 0.245671452774748 0.8059365724187821 1.0 0.9529868632359914 12 O95831 1 +Decreased circulating acth level 0.3410701153873309 0.2405767127701316 0.8098832006649332 1.0 0.9548509449147164 5 Q12824,Q99496 2 +Flat occiput 0.3313150671839511 0.2398565257561744 0.8104414845205152 1.0 0.9548509449147164 14 Q05086,O96011,P52732,O60762 4 +Abnormal muscle fiber type distribution 0.3562400004247769 0.2392005542155001 0.8109500729355619 1.0 0.9549519402743544 9 P50570 1 +Productive cough 0.3556479376346163 0.2370865666298967 0.8125896335845506 1.0 0.9555405310122662 9 Q6W2J9,Q9BZK7,Q6UN15,Q9NVR5 4 +Short ribs 0.3479471733811459 0.2369594241492797 0.8126882686714065 1.0 0.9555405310122662 11 Q9Y619 1 +Cutaneous melanoma 0.3186187918547725 0.2358832564493251 0.8135232611025212 1.0 0.9559018486442032 4 P42771 1 +Endocarditis 0.3609399406412934 0.2343810747991969 0.8146891496240369 1.0 0.9561904831653796 6 Q9NZ08 1 +Posteriorly rotated ears 0.2703742818246112 0.2327869714237805 0.8159268303307448 1.0 0.9568078025882149 106 Q8IY17,Q08J23,Q8NCH0,P07437,Q9Y619,Q4J6C6,Q15392,P23786,Q9BZK7,Q9HC07,Q10713,P42892 12 +Self mutilation 0.3512928138328829 0.2310281128043492 0.8172929618790314 1.0 0.9576660934588754 10 Q96RL7,Q10713 2 +Abnormality of facial musculature 0.2748789440914894 0.2288860160211145 0.8189575096793189 1.0 0.9584429134419364 78 Q13614,P50570,O43819,Q86U42,O75381,Q9BQP7,Q96TA2,Q13555,O96011,Q96RR1,Q9BQT8,Q9BUF5,Q12824,O95817,P07196,Q86VD7 16 +Aplasia hypoplasia of the breasts 0.3570084133577299 0.2268609880661172 0.820531838166942 1.0 0.9589807086935622 7 Q9Y619 1 +Thickened helices 0.3581063652256503 0.2251179055892831 0.8218875518194451 1.0 0.9598146811809628 6 Q96S52,Q9Y2B2,O43791 3 +Talipes valgus 0.3153123988345672 0.2241159824865405 0.8226670565496963 1.0 0.960189074338248 4 O00754,P49589,Q15233 3 +Abnormal blood glucose concentration 0.2714247134474126 0.2238969042579786 0.8228375246315847 1.0 0.960189074338248 102 P49748,Q13423,P31751,Q4J6C6,Q96CU9,Q5XKP0,P23786,O43772,Q9NSD9,P03886,Q9Y375 11 +Hypoplastic toenails 0.2959280290109328 0.2211419699648291 0.8249818918142475 1.0 0.9612265086217217 24 P23786 1 +Knee dislocation 0.3135706814572305 0.2180086376299982 0.8274223814337913 1.0 0.9624804108045334 4 Q9Y2D4 1 +Vocal cord paralysis 0.3081819966528464 0.216600412750167 0.8285197640460904 1.0 0.9624804108045334 19 P21912,P50402,Q9NR77,Q8WXH0 4 +Abnormality of coagulation 0.2636887436057596 0.2164344176404975 0.8286491405875769 1.0 0.9624804108045334 59 O75648,P48735,Q4KMQ2,Q6W2J9,O75381,Q9Y619,Q16836,Q96AX1,P51571,Q5XKP0,Q9BZK7,Q9Y487,O96011,Q9Y5S9,P38435,O60762 16 +Facial edema 0.2949403020470328 0.2158623813480285 0.8290950211000154 1.0 0.9624804108045334 24 Q14C86,P28070 2 +Oculomotor nerve palsy 0.3335684850885408 0.2151019166071064 0.8296878596449675 1.0 0.9624804108045334 5 Q12824,Q99496 2 +Venous insufficiency 0.354298276472334 0.212881690523164 0.831419243899489 1.0 0.9638995751461344 6 Q92766 1 +Bowing of the legs 0.2724895167200066 0.212714614054662 0.831549567256312 1.0 0.9638995751461344 50 Q96HY6,Q13126,Q32P28,Q9NR77,Q9Y619,Q9NUQ7 6 +Abnormality of the metaphysis 0.2739873690948144 0.2112099364707162 0.8327234574667339 1.0 0.9641809768653108 48 Q96HY6,P48735,Q13126,Q9Y2D4,Q99575,Q9NR45,Q9NUQ7,Q9HC07,O95831 9 +Kinetic tremor 0.2905576099076679 0.2111525655333762 0.8327682234139595 1.0 0.9641809768653108 33 P41440,Q8IY17,P20700,Q14108 4 +Blepharophimosis 0.2739464672708517 0.2108897568232821 0.832973297253849 1.0 0.9641809768653108 48 Q9BXW9,O75648,Q8WXI9,O75844,Q96DF8,Q6W2J9,P07437,Q9Y619,Q9BZK7,P38398,Q08J23,Q03164,P38159 13 +Abnormality of the umbilical cord 0.3503168415107356 0.210869783343913 0.8329888833441741 1.0 0.9641809768653108 8 Q9Y2B2,O75844,O60826 3 +Progressive inability to walk 0.3025067291637768 0.2097604768143388 0.8338546216904228 1.0 0.9641809768653108 20 Q96RR1,P00846 2 +Abnormality of corneal stroma 0.329802186144628 0.2091454385964018 0.8343347040974161 1.0 0.9641809768653108 13 Q16625 1 +Fragile nails 0.3446973376566098 0.2075002746841278 0.8356191781733615 1.0 0.9651593261410832 10 Q13555 1 +Corpus callosum atrophy 0.3172152427708261 0.2067627465864214 0.8361951513437287 1.0 0.9653323230344268 16 P20700,Q9H9P8,P51970,P51572,O75503,O00429 6 +Abnormal larynx physiology 0.3289831582318431 0.2059612600459837 0.8368211724974808 1.0 0.9658088946276656 13 Q15165 1 +Limited elbow movement 0.2815279820311515 0.203355553248003 0.8388571372910922 1.0 0.9679120814897216 39 Q96J02,Q9Y2D4,Q9H6K4,Q9UQE7,P23786,Q96AY3,Q8WXH0 7 +Inflammatory abnormality of the eye 0.2869965864437248 0.2021312724694158 0.8398141005251256 1.0 0.9682763744919366 35 Q96AX1,P04439,Q9UQE7,P28070,Q9NZ08,P02786,Q15800 7 +Short palm 0.2962490708821911 0.2010802938693418 0.8406357905017134 1.0 0.9686243579053386 21 Q9BZK7,Q9Y619,Q13555,O60762 4 +Brain imaging abnormality 0.2827032419481446 0.2005240081376764 0.8410707835070079 1.0 0.9686243579053386 38 Q05086,Q9BZK7,P03886 3 +Gastrostomy tube feeding in infancy 0.2876994223431388 0.1996705209206427 0.8417382703809613 1.0 0.9687396018208724 34 Q96J02,Q99720,Q9Y2B2,O60762 4 +Aplasia hypoplasia of the earlobes 0.3468563155922323 0.199429649416603 0.8419266693970804 1.0 0.9687396018208724 8 Q92766,P21964 2 +Pulmonary fibrosis 0.2948832531217304 0.1943932504760206 0.8458679744598947 1.0 0.9714009064860216 21 P09601 1 +Acne 0.3247998349750752 0.1899351781597917 0.8493599260112885 1.0 0.9740760670458576 13 Q9NZ08,Q92766,P21964 3 +Abnormality of facial adipose tissue 0.3050827003382983 0.189173783851905 0.8499566141173707 1.0 0.9744288163021064 4 Q03252 1 +Gingival bleeding 0.3245507765925595 0.1889937410612908 0.8500977223015285 1.0 0.9744288163021064 13 Q9BZK7 1 +Abnormality of the vertebral endplates 0.3459198410817133 0.1868443446580116 0.851782677101304 1.0 0.9753729846483588 6 Q9NR45 1 +Loss of ability to walk 0.3181132753039802 0.1862366197972968 0.8522592078277182 1.0 0.9756720271568268 14 P00846 1 +Lethargy 0.2713867385764238 0.1847252002543071 0.8534445793843783 1.0 0.9767084570856058 83 P49748,P50416,Q9Y619,Q96CU9,P23786,O43772,Q9Y375,P03886,Q96RR1,P46783,O96000 11 +Insulin resistant diabetes mellitus 0.3412070704885468 0.1812348715502944 0.8561832242577356 1.0 0.9789273109256796 8 O75844,P31751 2 +Abnormal renal collecting system morphology 0.3408371998704668 0.1752282482871411 0.860900288789642 1.0 0.982584607764444 7 Q9Y2B2,Q9BXW9 2 +Erectile dysfunction 0.3386222152138218 0.1731130504270348 0.8625625670676511 1.0 0.9829958311487949 8 Q06787,Q12824,P20700,Q99496 4 +Impotence 0.3386222152138218 0.1731130504270348 0.8625625670676511 1.0 0.9829958311487949 8 Q06787,Q12824,P20700,Q99496 4 +Abnormal iris pigmentation 0.3055943749004456 0.1719047551780266 0.8635124081488208 1.0 0.983336151059366 17 Q05086,O96011,Q8IY17 3 +Hepatic encephalopathy 0.2987880438612509 0.1688174356345523 0.8659402435115071 1.0 0.9839942265623012 4 Q6NUQ1 1 +Cardiac arrest 0.2857129442074455 0.1685052533507786 0.8661858111884118 1.0 0.9839942265623012 29 P04114,P50416,O43772,P49748 4 +Mildly elevated creatine kinase 0.2976144731990964 0.1684078066436085 0.8662624670045158 1.0 0.9839942265623012 19 O75648,P50570,Q16836,Q96RR1,Q92734 5 +Abnormal size of pituitary gland 0.3395653722524073 0.1679353479312569 0.8666341413890091 1.0 0.984066971851002 6 Q12824,Q14746,Q99496 3 +Restlessness 0.2831680532362096 0.166960491057434 0.8674011360727758 1.0 0.9842405619575642 33 O43464,P48449,Q15165,Q92804,P42892 5 +Calcification of the aorta 0.339156567449418 0.1667442642201116 0.8675712752542988 1.0 0.9842405619575642 6 P04114 1 +Renal tubular dysfunction 0.2759273138239858 0.1661443201462588 0.8680433763848132 1.0 0.984289485612817 39 O43819,P50416,Q96CU9,Q9Y375,P03886,Q9Y2V7 6 +Abnormality of central nervous system electrophysiology 0.2558070481098005 0.1626894894361442 0.8707629229479479 1.0 0.9856461532766688 141 Q13614,P03886,Q14108,P50897,Q8NC96,Q08J23,P49366,Q8NHS3,Q13045,P20700,O96011,P13073,Q9Y2B2,O75381,Q96F07,P48449,O75503,O60762,O95319,Q71SY5,Q9UBB6,Q9BSJ2,Q05086,P57740,P21964,Q9NUQ7,P07196 27 +Thoracic kyphosis 0.3115458737634197 0.1611342312359434 0.87198767987933 1.0 0.9856461532766688 14 O95831 1 +Coarse hair 0.2958551086278187 0.1607073138709712 0.8723239286793794 1.0 0.9856461532766688 19 P54802,O60568,Q9Y5P4,Q96AX1,Q9Y487,P62070,Q96A33 7 +Abnormal cd4 cd8 ratio 0.3160236293828341 0.1597772238497276 0.8730565662979088 1.0 0.9856461532766688 5 Q13432 1 +Submucous cleft of soft and hard palate 0.2830730783755624 0.1569155848615202 0.8753113770738037 1.0 0.9871656278586516 23 O75844,Q96DF8,Q6W2J9,Q9Y619,O60315,Q15392,Q08J23,O43505 8 +Flared metaphysis 0.3313859809124599 0.1561337076940231 0.8759276292726492 1.0 0.9872815050121384 9 Q96HY6,Q9NR45 2 +Hydroureter 0.3205545415476837 0.1560076862244159 0.8760269626758925 1.0 0.9872815050121384 12 Q9BXW9,Q9NVI1,Q6W2J9,Q9UQE7,P38398 5 +Neoplasm of the pituitary gland 0.3101327485358255 0.1558761981301259 0.8761306070968644 1.0 0.9872815050121384 14 Q99496,P48735,O75874,Q12824 4 +Joint laxity 0.2674661247132244 0.1546023272927963 0.8771348351454125 1.0 0.9876760634374144 77 Q96HY6,Q8WXI9,Q32P28,Q9Y619,P61978,Q9BZK7,Q9Y487,Q9NSD9,Q9HC07,Q96AY3,Q8NCH0 11 +Cns hypomyelination 0.272046524375885 0.1512240847929021 0.8797989518572791 1.0 0.989673808046528 40 Q99720 1 +Abnormality of the anterior fontanelle 0.2804012907505442 0.1509675088012878 0.8800013463159857 1.0 0.989673808046528 33 Q32P28,O75381,O75718,Q9Y619,Q9Y487,O96011,Q08J23 7 +Increased circulating antibody level 0.3230475051981881 0.1491389417189378 0.8814439984379323 1.0 0.9904240787877296 11 P28070,Q96AX1,Q14108 3 +Episodic ataxia 0.2923276141145949 0.148869174160627 0.8816568655816777 1.0 0.9904240787877296 4 P11166,O14936,Q9H936 3 +Type 1 muscle fiber atrophy 0.3317924717763582 0.1484713048511217 0.8819708303585752 1.0 0.9904240787877296 7 Q8WXH0,P61978 2 +Fetal distress 0.2821920100978239 0.1483775294185284 0.8820448326939816 1.0 0.9904240787877296 26 Q9Y375,P03886,Q96CU9 3 +Abnormal platelet function 0.2913564260278345 0.1459548364812372 0.8839570417945621 1.0 0.9911665749945238 4 O00203,P62070,Q8N5K1 3 +Multiple joint contractures 0.302147063937777 0.1455706987659456 0.8842603005353133 1.0 0.9911665749945238 16 P41440,O75844,Q99567 3 +Abnormal conjunctiva morphology 0.2816001214386602 0.1454009079747316 0.8843943478223404 1.0 0.9911665749945238 26 Q8NBM4,Q96AX1,P28070,Q9NZ08,P02786 5 +Widely spaced teeth 0.2780912342081304 0.1423559736439862 0.8867988360862593 1.0 0.9928820757337284 34 Q9Y2B2,Q9Y5P4,P51571,O60315,Q9UQE7,Q9BZK7,Q05086,Q96S52,P51812,Q96A33 10 +Hypoplasia of the iris 0.310042245172929 0.1423553724811172 0.8867993109091976 1.0 0.9928820757337284 5 O96028,Q13586 2 +Cerebral cortical atrophy 0.2663002797408494 0.1420559293585702 0.8870358283407611 1.0 0.99290148316868 96 Q96RL7,P00846,Q16625,Q9Y619,O75503,Q05086,Q96RR1,P03886,Q5KU26 9 +Abnormality of the musculature of the thigh 0.3282235064974627 0.1417709105366758 0.8872609619746921 1.0 0.9929081417355126 8 Q8WXH0,P07196,O14979 3 +Neoplasm of the adrenal gland 0.3162531933513364 0.1414728273557952 0.8874964247524826 1.0 0.99292635320542 12 P21912,P48735,P42771 3 +Fetal ultrasound soft marker 0.3058429300437451 0.1402332673758499 0.888475688033477 1.0 0.9935311939747348 14 Q9Y2B2,O75381,P61978,O60826,O96011,Q9BPU6 6 +Progressive psychomotor deterioration 0.3274956514475912 0.1396586991038048 0.8889296598519711 1.0 0.993548324482958 8 Q10713,O43681 2 +Fibrous tissue neoplasm 0.2905454886817127 0.1380531200803272 0.8901984356715582 1.0 0.9938051366993936 19 Q15392,P21912,Q12824,Q13126 4 +Abnormality of the coagulation cascade 0.2683473060899934 0.137964376773673 0.8902685714774892 1.0 0.9938051366993936 41 O75648,Q4KMQ2,Q6W2J9,Q9Y619,Q16836,P51571,Q5XKP0,Q9BZK7,Q9Y487,P38435,O60762 11 +Abnormality of the glabella 0.3266569658520027 0.1372383222302929 0.8908424207100301 1.0 0.9939694989695655 8 O96028,O60762 2 +Primary microcephaly 0.2930354191570314 0.1342887570328271 0.893174243304057 1.0 0.995835422635338 18 O43791,Q9UQE7,Q9BZK7,Q9Y4R8,Q03252,Q99496 6 +Peripheral cyanosis 0.3266364225534715 0.1339330611025462 0.8934555068207355 1.0 0.995903899089058 7 P55265,Q9Y3Z3,O95163,O75792,P51812,Q9UHD8 6 +Contractures involving the joints of the feet 0.2817847477737547 0.1333654457524884 0.8939043715455963 1.0 0.9959141178311736 21 Q8IZA0,P50402,P49902,Q08J23,Q8WXH0 5 +Abnormal nipple morphology 0.2533437120948558 0.1322626907612604 0.894776516528037 1.0 0.996575281688728 58 P83436,Q9Y2B2,Q8IY17,Q9Y5P4,P07437,P61978,Q9UQE7,Q9BZK7,P23786,Q92974,O60762 11 +Stage 5 chronic kidney disease 0.2789109033313118 0.1315086335658367 0.8953729572924001 1.0 0.996732154522222 27 P23786,P57740,Q14C86 3 +Abnormality of the synovia 0.2658937701496137 0.1311133219273268 0.8956856627653684 1.0 0.996732154522222 80 Q9NQT5,Q96AY3,Q9Y2D4,O75718,Q96AX1,Q9Y487,P38398,Q9Y2D2,Q9Y2B2,Q9NR45,O94979,Q9Y584,Q9BPU6,Q9Y5S9,Q03252,Q9BXW9,O75844,Q9UQE7,Q9Y4R8,O96028,Q9NUQ7 21 +Proximal amyotrophy 0.3032590299039336 0.131046195147655 0.8957387640308974 1.0 0.996732154522222 14 Q13586,Q9BQP7,P50402,O14979,Q92734,Q8WXH0,P07196 7 +Diarrhea 0.2614705760739188 0.1299112689024576 0.8966366285528009 1.0 0.9974862297014214 69 Q96J02,P54802,Q13423,Q08J23,O43464,P50416,Q9BQP7,P03886,Q9Y2V7,P42892,P02786 11 +Abnormality of the wrist 0.2775632323434489 0.1285930600681648 0.8976796579767987 1.0 0.9981967337944756 31 Q9Y2D4,Q9NR45,Q9H6K4,Q9NUQ7,O95831 5 +Pollakisuria 0.2852055681450249 0.1280194460135292 0.8981335839717661 1.0 0.9984159841453008 4 P54886,Q06787,O60934 3 +Abnormal visual electrophysiology 0.2646648347615099 0.1277152505030446 0.8983743207753665 1.0 0.9984385851600616 44 Q8WWY3,Q8IY17,P00846,O75503,O43681,O14773,P50897 7 +Oculomotor apraxia 0.2760409413065148 0.1265443598282911 0.8993010371850834 1.0 0.9990532614829004 22 Q9NQT5,Q9Y2B2,P36405,Q10713,O14773,P18887 6 +Abnormal ureter morphology 0.2770574535376726 0.1260573502954249 0.8996865276206376 1.0 0.9991615518807276 24 Q9BXW9,O75844,Q9UQE7,P23786,P38398 5 +Bicornuate uterus 0.3209649200718408 0.1250001195147713 0.9005234557228736 1.0 0.9993780039946264 9 Q9NVI1,Q69YQ0,Q9BXW9,P38398 4 +Cervical ribs 0.2618122977346321 0.123374438348584 0.901810597657636 1.0 0.9998439394713312 3 Q9UHX1,Q9Y5S9 2 +Turricephaly 0.3212715546281096 0.1220429861214134 0.9028649746956684 1.0 1.0 8 Q92766 1 +Elbow flexion contracture 0.2770126044672703 0.1219941990885197 0.9029036124131784 1.0 1.0 28 P23786 1 +Decreased activity of the pyruvate dehydrogenase complex 0.2745352042123391 0.1197527751949456 0.9046789925681747 1.0 1.0 22 Q7KZN9,Q96CU9 2 +Abnormality of the elbow 0.2527692971174393 0.1192993335555293 0.905038211475398 1.0 1.0 59 Q9Y619,Q9H6K4,P23786,Q96AY3,Q03164 5 +Depression 0.264381262772404 0.1182085466626642 0.9059024181821856 1.0 1.0 95 Q96RL7,Q92766,Q71SY5,P20700,O43464,Q9UBB6,Q6DKK2,Q15165,Q92804,Q96RR1,P03886,P50897,Q08J23,Q9NUQ7 14 +Capillary hemangioma 0.3201555411536056 0.1164157421402321 0.9073230597980444 1.0 1.0 7 Q15436,Q9UHX1,P16435,P21281,Q7LGA3,Q9UBM7 6 +Abnormal enchondral ossification 0.2756306249378248 0.1161322061223332 0.9075477646985104 1.0 1.0 26 Q96HY6,O75381,Q9Y619,Q9NUQ7,O96011,P38435 6 +Abnormal urine cytology 0.2716507449882606 0.1160161912887831 0.9076397096546682 1.0 1.0 36 Q9UBQ7,Q6W2J9,P09601,Q9BZK7,P21912,Q14108,Q03252 7 +Abnormality of the scrotum 0.2606185709762116 0.1153441338185285 0.9081723580507576 1.0 1.0 49 Q8IY17,Q9NSD9,Q9UNW1 3 +Skin ulcer 0.2753426121602335 0.1147553309201653 0.9086390558337424 1.0 1.0 26 Q03518,P48735,Q8IZA0,P52732 4 +Transposition of the great arteries 0.3198480671875587 0.1141162567625269 0.9091456353765446 1.0 1.0 6 Q9Y2B2,O75844 2 +Dolichocephaly 0.2722010484459885 0.113701663893254 0.9094742934814022 1.0 1.0 35 Q96J02,Q9BXW9,Q9Y2D4,O75381,P61978,Q4J6C6,O96011,O96028,Q03164 9 +Short palpebral fissure 0.2752324563837836 0.1131335406256739 0.9099246841116332 1.0 1.0 28 P83436,Q9BXW9,O75844,Q9NVI1,P07437,Q9Y619,P38398,P98175,Q13868,Q03164 10 +Abnormal aortic arch morphology 0.3022444814596092 0.1107958698715039 0.9117782205531346 1.0 1.0 13 O00459,Q92766,P21964,Q96DF8 4 +Redundant skin 0.2728755601585766 0.1093244448937221 0.912945158575064 1.0 1.0 23 Q8NCH0,Q9Y487,P38435 3 +Ankyloblepharon 0.2566845367810606 0.1086598862979682 0.9134722594994468 1.0 1.0 3 Q6W2J9 1 +Proptosis 0.2562253661543484 0.1067127863536949 0.91501683849005 1.0 1.0 53 Q96J02,Q9BXW9,O75844,Q32P28,Q9Y2D4,O75718,O60568,P61978,O96028,P38398,Q9BPU6,P62070,Q69YQ0,O75431,Q12824,Q5KU26,Q99496 17 +Unusual infection by anatomical site 0.305015386349824 0.1056099960127578 0.9158917934382008 1.0 1.0 12 P02786,Q9NZ08,Q9H9P8 3 +Blindness 0.2624888006596025 0.1049496122299617 0.9164157914373592 1.0 1.0 77 Q8NBM4,O75380,P36405,Q9NZ08,P03886,P50897,O96000,P52732,O00459,Q8NHS3,Q9Y375,O43676,Q8WWY3,P00846,Q6W2J9,Q96CU9,P21912,Q12824,Q8N183,Q9H6K4 20 +Spinal rigidity 0.2953518619648845 0.1040592979720111 0.9171222909578 1.0 1.0 14 Q9BQP7,P50402,Q8WXH0,O95817 4 +Abnormality of hair pigmentation 0.2706921559004016 0.1028084329648777 0.9181150121955308 1.0 1.0 22 Q05086 1 +Recurrent pneumonia 0.2746610581427275 0.1026744602189555 0.9182213442869724 1.0 1.0 21 Q13432,Q71SY5,P20700,P78318 4 +Hypoplasia of the pons 0.2875762731253031 0.101643008775621 0.9190400401453052 1.0 1.0 17 Q9UNW1,Q9Y3B2 2 +Emphysema 0.3109740053678118 0.1011784124997376 0.9194088330958384 1.0 1.0 10 Q9NSD9 1 +Anencephaly 0.2981478301713888 0.0978142728876701 0.9220797736087488 1.0 1.0 13 Q92766,Q9Y3Z3,P21964 3 +Abnormality of skeletal muscle fiber size 0.2835185906220737 0.0974625863629655 0.9223590444965456 1.0 1.0 18 O95831 1 +Abnormal vertebral morphology 0.2598118322198014 0.0969013242051993 0.922804757194252 1.0 1.0 106 Q96HY6,Q96J02,P48735,P54802,Q13045,Q32P28,O75718,Q9Y619,Q99575,P61978,Q9NUQ7,Q10713,Q14108,Q96AY3,Q8NCH0,O95831 16 +Abnormality of thalamus morphology 0.2909502866263694 0.0961992121143119 0.923362356555983 1.0 1.0 15 O43819,P11166,Q96RR1,Q12824,Q96EY7,Q99496 6 +Phthisis bulbi 0.3123740144103363 0.0957131438480688 0.9237484015483128 1.0 1.0 6 Q9UQE7 1 +Diminished movement 0.2765200101361786 0.0952783870492172 0.9240937091816646 1.0 1.0 20 O95831 1 +Abnormality of the thoracic cavity 0.3092999891599786 0.0929298688255833 0.92595927652481 1.0 1.0 9 Q92990,Q9Y3A5,Q12824,Q99496 4 +Recurrent skin infections 0.3007166136674457 0.0927223457998603 0.9261241441043312 1.0 1.0 12 Q8NCH0 1 +Infantile onset 0.2531703889733543 0.0898834485987363 0.9283798340124844 1.0 1.0 169 Q9P0J0,Q70HW3,Q5JRX3,P23786,Q9BUF5,P49366,P49748,Q5BJH7,Q8WXI9,O75648,P20700,Q9NR77,Q96TA2,Q96AX1,Q5XKP0,Q9Y375,P35241,O95831,P51970,Q96CU9,Q9NSD9,Q92643,O60762,O75787,Q9H9P8,Q9UBB6,Q9BSJ2,Q9UEY8,Q10713,P55263 30 +Flat face 0.2695169904077987 0.0894385693458063 0.928733372372564 1.0 1.0 25 O75381,P07437,Q13555,Q9Y487,O96011,Q03164 6 +Diaphragmatic eventration 0.2882124352331583 0.0853646630368537 0.93197148539636 1.0 1.0 5 O60568,Q15650,Q96DA6,P08243 4 +Diffuse mesangial sclerosis 0.2891022328906434 0.0839623622138831 0.9330863566642558 1.0 1.0 14 Q14C86,P57740,O95470,Q8N1F7 4 +Large forehead 0.3069743784861852 0.0834548132994816 0.9334899057628968 1.0 1.0 7 Q96AX1,O43791 2 +Atrioventricular canal defect 0.3062216461438801 0.0816822250460859 0.9348994134786786 1.0 1.0 7 P36776,Q9UHX1,P24468,O60826,P19022,Q9UBM7 6 +Athetosis 0.286104843280319 0.080335510029979 0.9359704165505438 1.0 1.0 15 Q96CU9 1 +Tube feeding 0.2563533095468223 0.0773964186420927 0.938308189748182 1.0 1.0 70 Q96J02,Q9Y2B2,O75648,Q71SY5,Q9UBB6,Q99720,P61978,Q8TD30,Q08J23,Q9NUQ7,O60762 11 +Abnormal enzyme coenzyme activity 0.2523806919018038 0.0770290232351731 0.9386004563514924 1.0 1.0 182 P49748,Q96RL7,P00846,P41440,P50416,Q16625,Q9Y619,O15118,P23786,P28070,O43772,Q9NSD9,P03886,Q5XKP0,Q96RR1,Q96AY3,Q9Y2V7,P55263 18 +Multiple cafe au lait spots 0.2946207567501145 0.0752556032531185 0.9400113447370892 1.0 1.0 12 P21912,Q9BXW9,O60566,P38398 4 +Aplasia hypoplasia involving bones of the lower limbs 0.2611766820704146 0.0746533710480645 0.9404905086027336 1.0 1.0 86 Q9BZK7,Q69YQ0,Q96AY3,Q08J23,Q03164,O75648,Q9Y2D4,Q13555,P13073,Q8N0X7,Q99575,O95831,Q96HY6,Q9Y2B2,Q9Y5P4,Q9NR45,Q9BPU6,Q9Y5S9,Q9Y619,Q9UQE7,Q9Y4R8,O00116,O96028 23 +Thoracic scoliosis 0.2938679874300519 0.0731651338959596 0.94167471112009 1.0 1.0 12 O00459,Q96J02 2 +Macular atrophy 0.3015314222467994 0.0710304069157079 0.943373555383173 1.0 1.0 6 Q8WWY3 1 +Abnormality of the urinary system physiology 0.2371618406524498 0.0696198898555133 0.9444962055360216 1.0 1.0 265 P61457,Q4J6C6,P23786,Q9BZK7,O43772,Q9NZ08,P03886,P49748,Q16625,Q5XKP0,Q9Y375,Q8NCH0,P00846,P09601,Q96CU9,Q9NSD9,Q9Y2V7,P48735,Q8IY17,Q13423,O43819,P50416,Q14C86,Q9Y619,Q9H6K4,Q9BQT8 26 +Abnormality of epiphysis morphology 0.2512938292897484 0.0694217631378221 0.9446539062288668 1.0 1.0 53 Q96HY6,Q9Y2B2,Q9Y2D4,O75381,Q9Y619,Q9NR45,P38435,Q9NUQ7,O96011,Q9HC07,O95831 11 +Multicystic kidney dysplasia 0.269730461052603 0.0691814323024364 0.9448452025688878 1.0 1.0 20 O75381,O43791,Q9UQE7,P36405,O96011,Q10713 6 +Lumbar hyperlordosis 0.2801462647798442 0.0678714235592145 0.9458879869779476 1.0 1.0 16 Q96HY6,Q96J02,Q96AX1 3 +Bone cyst 0.2401294498381926 0.0662363628425792 0.9471896469654668 1.0 1.0 3 P21912,Q15437 2 +Conjunctival hamartoma 0.2401294498381926 0.0662363628425792 0.9471896469654668 1.0 1.0 3 P21912,Q15437 2 +Increased muscle fatiguability 0.2788212435233141 0.0641292184236346 0.948867336785502 1.0 1.0 5 P53985,Q7Z392,Q13586,P24468 4 +Congestive heart failure 0.2479760011109613 0.0634692283355348 0.949392862054981 1.0 1.0 61 O43819,Q70HW3,P07437,Q9Y375,P03886,O95817 6 +Increased urine alpha ketoglutarate concentration 0.2784974093264225 0.0634326763742492 0.9494219676516396 1.0 1.0 5 P21912,P30038,P00367,P21281 4 +Bulbous nose 0.2548922190982903 0.0634217161940101 0.9494306950373912 1.0 1.0 44 P23786 1 +Aplasia hypoplasia involving the nose 0.2643231342731742 0.0629248211335746 0.9498263696008628 1.0 1.0 27 Q08J23,Q5KU26 2 +Rod cone dystrophy 0.2575810656054066 0.0617188142535163 0.9507867569239444 1.0 1.0 40 Q8WWY3,P00846,O96011,P03886,P04114,P38435 6 +Resting tremor 0.2641042255786832 0.0606597455007388 0.9516301910497372 1.0 1.0 21 Q96RR1,Q9H6K4 2 +Emotional lability 0.2496843959676056 0.0575884804188334 0.9540764257390026 1.0 1.0 53 Q96RL7,Q9P0J0,Q7KZN9,Q15165,Q96CU9,Q92804,O43681,Q8N0X7,Q12824 9 +Pancytopenia 0.2617979569436998 0.0574168380929698 0.9542131502700156 1.0 1.0 35 Q96J02,Q9BZK7,Q9NSD9,Q14108,Q9Y2V7 5 +Nephritis 0.266356528849421 0.0568419594615609 0.9546710891348154 1.0 1.0 20 Q14C86,Q96AX1,Q8N1F7,P57740,Q03252 5 +Fatty replacement of skeletal muscle 0.2942346413842562 0.0557771484107937 0.955519339524119 1.0 1.0 6 Q8NFF5,P51114 2 +Premature skin wrinkling 0.2690015772295011 0.0557252904285365 0.955560651953981 1.0 1.0 19 Q9BZK7,Q9Y487,Q9UP83 3 +Enlarged thorax 0.2836034052046113 0.0553808129219318 0.9558350814456756 1.0 1.0 13 Q32P28,O75844,Q99575,Q96AX1 4 +Cerebral white matter atrophy 0.2591116831027423 0.0552555396477018 0.9559348822398844 1.0 1.0 22 P20700,Q9H9P8,P51970,P51572,O75503,O00429,Q9UP83,Q93009 8 +Proximal muscle weakness in upper limbs 0.287134650416723 0.0551229363037009 0.9560405233944668 1.0 1.0 12 P07196,Q8WXH0,P50570 3 +Pseudobulbar paralysis 0.2942580035761157 0.0551215257695422 0.9560416471293848 1.0 1.0 7 P20700,O94979,Q14203 3 +Proximal muscle weakness in lower limbs 0.2682631795147494 0.0531897061635991 0.9575807572978 1.0 1.0 19 P50570,P35670,P50402,Q96RR1,Q8WXH0,P07196 6 +Abnormality of the peritoneum 0.2707913590215388 0.0528652480485971 0.9578392736987718 1.0 1.0 18 Q14C86,Q8N1F7,P57740,P42771,P38398 5 +Bone marrow hypercellularity 0.291810471064188 0.0521360364035616 0.9584202991017932 1.0 1.0 10 Q6W2J9,P62263,Q9BZK7,Q6UN15 4 +Peritonitis 0.2776327067405079 0.0499988156375364 0.9601233321273144 1.0 1.0 14 Q14C86,P57740,P38398,Q8N1F7 4 +Abnormal clavicle morphology 0.2610885366666918 0.0494458039389314 0.9605640265149696 1.0 1.0 21 Q9Y2B2,O75844,Q6W2J9,Q9Y619,Q9Y5S9,Q96AY3 6 +Abnormality of hindbrain morphology 0.2315085582052861 0.0490531749600928 0.9608769194203292 1.0 1.0 278 Q9Y3B2,Q99720,Q9BQP7,Q5JRX3,P23786,Q9BZK7,Q96B26,Q14108,Q9NQT5,Q5BJH7,Q8NHS3,O75648,P20700,P41440,Q16625,Q6DKK2,P07437,Q96TA2,Q5XKP0,Q9Y487,Q9UNW1,P13073,O14773,Q8N0X7,Q92974,P00846,P51970,Q96F07,O75503,Q96CU9,Q9UP83,Q96RR1,Q99567,Q9Y2V7,Q96D71,Q92643,Q12824,O60762,P83436,O75787,Q8IY17,Q9H9P8,P51572,Q9H6K4,Q9UQE7,Q10713 46 +Osteopenia 0.2531046055734008 0.0483239740953301 0.961458048305341 1.0 1.0 70 Q13126,Q32P28,Q9NWM8,P61978,Q9Y487,Q9NSD9,Q14108,Q96AY3 8 +Cirrhosis 0.2593197571280093 0.0483070287467966 0.9614715529655544 1.0 1.0 36 P22830,P11717,Q9NSD9,Q10713,Q14108,Q9Y2V7 6 +Hypopigmented skin patches 0.2593734334517396 0.0462782858865576 0.9630884461152736 1.0 1.0 25 Q9BXW9,Q92766,Q8IZA0,P38398,P21964 5 +Epileptic encephalopathy 0.2586056714361414 0.0461642092448528 0.9631793689305757 1.0 1.0 24 Q8NC96,Q96F07 2 +Small hand 0.2603664197707108 0.045883703925717 0.9634029428800877 1.0 1.0 27 Q9Y619,Q9UQE7,Q06787,Q9Y4R8,Q69YQ0,Q08J23,O60762,Q99496 8 +Abnormal circulating androgen level 0.2796837239395647 0.044940019029078 0.9641551184792644 1.0 1.0 13 Q12824,Q13423,Q99496 3 +Arrhinencephaly 0.2884451351308148 0.0444180774961658 0.9645711521112216 1.0 1.0 10 Q92766,P21964 2 +Congenital malformation of the left heart 0.2882018407818895 0.0439935804265232 0.964909520992414 1.0 1.0 6 O43791 1 +Shyness 0.2502151087339656 0.0437664674139724 0.9650905565862936 1.0 1.0 4 Q06787 1 +Keratoconjunctivitis 0.2873947066119091 0.0407262662116447 0.9675141215541024 1.0 1.0 8 Q9NZ08 1 +Increased intracranial pressure 0.2642678709916038 0.0398104160764642 0.9682442719876176 1.0 1.0 19 P21912,Q9NZ08,Q8NBM4,Q12824 4 +Optic nerve hypoplasia 0.2696086253586356 0.0359346910404494 0.9713344342714894 1.0 1.0 16 Q9NVI7,Q8WXI9,Q9NVI1,P61978,O43791,P07196 6 +Delusions 0.2694202362157437 0.0311108483506455 0.975181138125654 1.0 1.0 15 Q96RL7,O43681,P21964 3 +Large beaked nose 0.2616580310880804 0.0304879456892364 0.975677906860042 1.0 1.0 5 O75792,P55265,Q9Y3Z3,Q12797 4 +Malignant neoplasm of the central nervous system 0.2554641227608017 0.0294909924418947 0.9764730028085952 1.0 1.0 21 P48735,P07437,P21912,P42771,Q12824 5 +Leukodystrophy 0.2406382953647707 0.0284061409258439 0.9773382264285028 1.0 1.0 58 Q9P0J0,P20700,Q7KZN9,O43819,O75380,Q96CU9,P21912,O43678,Q9Y3Z3,P03886,Q9Y375,O43681,O43676,O96000 14 +Unilateral renal agenesis 0.2667793916460541 0.0279622208709842 0.9776922827337022 1.0 1.0 16 Q9Y2V7 1 +Proportionate short stature 0.2565377417680762 0.0270692313021238 0.9784045156277894 1.0 1.0 33 Q96HY6,Q9Y619,Q8IY17,Q13555 4 +Limited elbow extension 0.268677755682879 0.0261623746951933 0.9791278262461957 1.0 1.0 14 Q96J02,Q9H6K4 2 +Abnormal shoulder morphology 0.256229634871786 0.0256315475959288 0.979551222988316 1.0 1.0 29 Q96PU5 1 +Decreased circulating level of specific antibody 0.27850295855498 0.0247844275132199 0.9802269122882554 1.0 1.0 7 Q9Y2V7 1 +Male sexual dysfunction 0.2740558627889727 0.0234832856058482 0.9812647709635796 1.0 1.0 12 P20700,O43464,O75298,Q06787,Q12824,Q99496 6 +Skin dimple 0.25535446242191 0.0234041109021791 0.9813279258796505 1.0 1.0 28 Q08J23,Q03164,P49366 3 +Agnosia 0.274700356333006 0.0203180977903183 0.9837896188179284 1.0 1.0 6 O75787,P52701,P43246,O96008,Q16658 5 +Abnormal right ventricle morphology 0.2755566411983087 0.0196927150848662 0.984288502174462 1.0 1.0 7 Q9H267,Q15233 2 +Pes cavus 0.2553992350466766 0.0193853904324137 0.9845336649659152 1.0 1.0 98 Q96RL7,Q9BRK0,P50570,Q99720,Q9NR77,Q9H6K4,Q96RR1,Q08J23,O95831 9 +Atrophy degeneration affecting the brainstem 0.2645841375217552 0.0184354448896762 0.9852914763093216 1.0 1.0 15 P20700,O00429,Q9UP83,Q96RR1,Q96DA6 5 +Glioblastoma multiforme 0.2747893713545076 0.0183964957359492 0.9853225479683432 1.0 1.0 7 P52701,O75874,P43246,P04637,P42771,Q16658 6 +Thoracic kyphoscoliosis 0.2728675261854298 0.0173881588713722 0.9861269555806322 1.0 1.0 6 Q96J02 1 +Pancreatic adenocarcinoma 0.2750567628932888 0.0163774538074796 0.986933266593063 1.0 1.0 10 P52701,P78549,P43246,Q5HYI8,P42771,P04637,P38398,Q16658,Q6P1J9 9 +Atrophy degeneration affecting the cerebrum 0.240441341646992 0.0147295066345743 0.9882479790194438 1.0 1.0 244 Q9Y3B2,Q5JRX3,Q96B26,P03886,P50897,Q8NC96,Q9NQT5,Q08J23,Q5BJH7,Q8NHS3,O75648,P20700,Q16625,Q6DKK2,P13073,O14773,O95831,Q5KU26,Q9Y2B2,P00846,O43464,P51970,Q96F07,O75503,Q9NR45,Q9UP83,Q9NSD9,Q96RR1,Q9Y2V7,Q96D71,O60762,Q96RL7,P83436,O95319,O75787,Q71SY5,Q9H9P8,Q9UBB6,P51572,Q9Y619,Q05086,Q9UQE7,Q10713,Q9NUQ7,P55263 45 +Achilles tendon contracture 0.2723516291105007 0.0146837046038739 0.9882845198007786 1.0 1.0 11 Q08J23,Q8WXH0 2 +Acute coronary syndrome 0.2580303813853536 0.0137282283255167 0.9890468026206678 1.0 1.0 18 P04114,O75844,Q9NZ08,Q8NBM4 4 +Round face 0.2500784318624558 0.0115695805197896 0.990769016264606 1.0 1.0 21 Q32P28,Q9Y2B2,O75718,Q03164 4 +Abnormality of the vasculature of the eye 0.2480826886673777 0.0106579728743249 0.9914963289864716 1.0 1.0 69 Q8WWY3,Q92766,Q8NBM4,Q96DF8,P00846,Q96AX1,P38435,P36405,P28070,Q9NZ08,P03886,P21964,P02786,P04439 14 +Ventriculomegaly 0.2482062050142599 0.0094152297514631 0.9924878445328388 1.0 1.0 177 P23786,Q9BZK7,Q9Y3Z3,Q69YQ0,Q13045,P20700,Q16625,P07437,Q15392,Q9Y487,P38398,Q8NCH0,Q5KU26,Q86XL3,P00846,O43464,Q6W2J9,Q96F07,P51970,Q9NR45,O94979,Q96CU9,Q9UP83,Q9BPU6,Q99567,Q9Y2V7,Q12824,Q03252,O60762,Q96RL7,Q9BXW9,O75787,Q71SY5,O43819,Q9BVA1,Q9UQE7,Q10713,O96028,O60566 39 +Severe global developmental delay 0.2464291598328521 0.0090855975220575 0.9927508417456374 1.0 1.0 67 O75648,Q71SY5,P00846,P51970,Q9BZK7,O96011,P03886,P55263,O60762 9 +Truncus arteriosus 0.2701695186272433 0.0077768288720157 0.9937950508559984 1.0 1.0 9 Q92766 1 +Hypoplastic ilia 0.2696665780010693 0.0069084840674775 0.9944878710704111 1.0 1.0 9 Q99575 1 +Bilateral ptosis 0.2605885342416303 0.0066694415177989 0.9946785950344348 1.0 1.0 14 Q9Y5P4 1 +Cranial asymmetry 0.264866683659762 0.00537729754125 0.9957095579895936 1.0 1.0 6 O96028 1 +Cerebral hypomyelination 0.258934372969461 0.0045399345985837 0.996377668720055 1.0 1.0 15 Q9Y2B2,Q9BTW9,O43175,Q9UI10,P54136,P00387,Q8NB90,P51572,O75746,Q9H553,Q9H7D7,Q9NR50,O75340,Q14232 14 +Supernumerary bones of the axial skeleton 0.2449527145845105 0.0040371173910095 0.9967788551134404 1.0 1.0 5 Q9Y5S9 1 +Simple ear 0.2444948186528472 0.0033966184258376 0.9972898958101728 1.0 1.0 5 P16435,Q92925,Q96KP1,O60231 4 +Motor seizure 0.2524641790789098 0.0027145469846705 0.99783410753135 1.0 1.0 105 O60762,Q8NHS3,P00846,Q9UBB6,Q9Y619,O75503,Q05086,Q5XKP0,P03886,P13073,Q08J23,Q9NUQ7,O14653 13 +Abnormal sclera morphology 0.2504052532274976 0.0020115640387338 0.998395005192834 1.0 1.0 29 Q8NCH0,Q96AY3,O75718,Q9Y3B2 4 +Abnormal glomerular mesangium morphology 0.2571283143686942 0.0003049426917179 0.9997566909381196 1.0 1.0 15 Q14C86,P57740,O95470 3 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..25fa9fc79b80e36f3aa0f69ce5ca1c00eed08616 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality of von willebrand factor", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Adult onset sensorineural hearing impairment", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonate wasting renal tubular acidosis", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid nasal tip", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Chin with horizontal crease", "Choanal stenosis", "Choking episodes", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clinodactyly of the 2nd finger", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Common atrium", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of renal pelvis", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid apraxia", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Imbalanced hemoglobin synthesis", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Inappropriate sexual behavior", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urinary potassium", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the 5th finger", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist movement", "Lingual dystonia", "Lipemia retinalis", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low self esteem", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Menorrhagia", "Mental deterioration", "Mesomelia", "Metabolic acidosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Percussion myotonia", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Punctate opacification of the cornea", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal sodium wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Sex reversal", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASS", "ABAT", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADSL", "AFG3L2", "AGA", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANXA11", "AP1B1", "AP1S2", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APOB", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARL6IP1", "ASAH1", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATIC", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7A", "ATP7B", "ATRIP", "ATRX", "ATXN10", "AURKA", "B3GAT3", "B4GAT1", "BAG3", "BANF1", "BARD1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCKDHA", "BCKDHB", "BCOR", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRCA1", "BRD4", "BUB1B", "BUB3", "BUD23", "C19orf70", "C1QBP", "CAD", "CALR", "CAMK2G", "CANT1", "CAPN1", "CARS", "CARS2", "CASK", "CAST", "CBX2", "CCDC22", "CCDC47", "CCT5", "CD2AP", "CD3EAP", "CDC40", "CDC42", "CDC73", "CDH2", "CDK4", "CDK5", "CDKN2A", "CELF2", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHORDC1", "CHP1", "CHST14", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLCN7", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNP", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COQ9", "COX15", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2A1", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CUL3", "CUL4B", "CUL7", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DBT", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DIAPH1", "DIP2B", "DKC1", "DLAT", "DLD", "DLST", "DNAAF2", "DNAAF5", "DNAJB11", "DNAJB6", "DNAJC13", "DNAJC19", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DPP9", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DYNC1H1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EHHADH", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF3F", "EIF4A3", "EIF4G1", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "EPB41", "EPRS", "ERAL1", "ERAP1", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ESCO2", "ESS2", "ETFA", "ETFB", "ETFDH", "EXOC2", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EZR", "FANCD2", "FANCI", "FAR1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD2", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALNT2", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GATC", "GBA", "GCDH", "GCLC", "GDAP1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLS", "GLUD1", "GM2A", "GNAI2", "GNAI3", "GNPAT", "GNS", "GOSR2", "GOT2", "GPAA1", "GPD2", "GPI", "GPT2", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUF1", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HCFC1", "HELLS", "HEXA", "HEXB", "HEXIM1", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-C", "HMGA1", "HMGB3", "HMGCL", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IFT81", "IGBP1", "IGF2BP2", "IGF2R", "IMPAD1", "INTS1", "INTS8", "IRF2BPL", "IRS4", "ISCU", "ITCH", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KIAA0319L", "KIDINS220", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KMT2A", "KMT2B", "L2HGDH", "LAMB1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDLR", "LEMD2", "LEMD3", "LETM1", "LIPA", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPAP1", "LRPPRC", "LRRC8A", "LSS", "MACF1", "MAGED2", "MAGT1", "MAN2B1", "MAPK1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MED12", "MED17", "MED23", "MED25", "MED27", "MESD", "MFN2", "MFSD8", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MOCS1", "MOGS", "MORC2", "MPDU1", "MPG", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MYH9", "MYO6", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEFL", "NEK9", "NELFA", "NEPRO", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP10", "NOP56", "NPC1", "NPC2", "NPM1", "NR2F2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCLN", "OGDH", "OGT", "OPA1", "OPA3", "ORC6", "OXCT1", "P3H1", "P4HB", "PABPN1", "PAFAH1B1", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDHA1", "PDHB", "PDHX", "PDK3", "PEPD", "PEX11B", "PEX14", "PEX19", "PEX3", "PFKM", "PFN1", "PGK1", "PGM1", "PHB", "PHF6", "PHGDH", "PHIP", "PI4KA", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PISD", "PITRM1", "PKN1", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPOX", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKAR1A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PTCD3", "PTDSS1", "PTPN1", "PTRH2", "PUF60", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QRSL1", "RAB11B", "RAB18", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RABL3", "RAC1", "RAD21", "RAD50", "RAD51C", "RAI1", "RALA", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RBPJ", "RDH11", "RDX", "REEP2", "REPS1", "RFC1", "RFC2", "RFT1", "RHOA", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNPC3", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS29", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RREB1", "RRP7A", "RSPRY1", "RSRC1", "RTN2", "SAMHD1", "SAR1B", "SARS", "SARS2", "SBDS", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SDHA", "SDHB", "SDHC", "SEC23A", "SEC23B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEPT9", "SERPINB6", "SERPINH1", "SETD2", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC27A4", "SLC2A1", "SLC33A1", "SLC35A3", "SLC37A4", "SLC44A1", "SLC5A6", "SLTM", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPOP", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SRCAP", "SRP54", "SRP72", "SSBP1", "SSR4", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STT3A", "STT3B", "STUB1", "STX3", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCF20", "TCOF1", "TECR", "TELO2", "TERF2IP", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIMM22", "TIMM50", "TIMMDC1", "TKT", "TMCO1", "TMEM126A", "TMEM126B", "TMEM165", "TMEM199", "TMEM43", "TMEM70", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOP3A", "TOR1A", "TOR1AIP1", "TP53", "TPI1", "TPM1", "TPM3", "TPP1", "TPP2", "TRAPPC11", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSPYL1", "TTC19", "TTC37", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUFM", "TWNK", "TXNDC15", "UBA1", "UBAC2", "UBAP1", "UBE3A", "UBIAD1", "UBR7", "UBTF", "UFC1", "UFD1", "UFSP2", "UMPS", "UNC119", "UNC45A", "UPF3B", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP7", "USP9X", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VMA21", "VPS13A", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WBP11", "WDR1", "WDR26", "WDR36", "WFS1", "WIPI2", "XPNPEP3", "XRCC1", "YARS", "YARS2", "YEATS2", "YIF1B", "YME1L1", "YWHAE", "YWHAG", "ZC3H14", "ZCCHC8", "ZEB2", "ZFR", "ZMPSTE24", "ZNF148", "ZNF644", "ZPR1"], "leading_proteins": ["ABCB1", "ABCD4", "ACADVL", "ACAT2", "ACSL4", "ACTN1", "ADAR", "ADD3", "ADK", "AGPS", "AIFM1", "AIP", "AKT2", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALG2", "ANKLE2", "ANO6", "ANXA11", "AP2M1", "AP3B1", "APOB", "APRT", "ARHGEF2", "ARL3", "ASNA1", "ASNS", "ASPH", "ATAD3A", "ATP1A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1B2", "ATP7B", "ATXN10", "B4GAT1", "BAG3", "BCAP31", "BCOR", "BRCA1", "BUB1B", "C19orf70", "CAMK2G", "CANT1", "CARS", "CASK", "CCDC22", "CCDC47", "CDC73", "CDH2", "CDKN2A", "CELF2", "CFL2", "CHST14", "CISD2", "CLN5", "CNNM4", "CNOT1", "COG2", "COG5", "COG6", "COG7", "COL4A3BP", "COLEC12", "COMT", "COX15", "COX2", "COX4I1", "CPT1A", "CPT2", "CRTAP", "CTNNB1", "CTPS1", "CXorf56", "CYB5R3", "CYFIP2", "DCPS", "DCTN1", "DCTN4", "DDRGK1", "DDX41", "DHCR24", "DHCR7", "DHPS", "DHX16", "DNAAF2", "DNAAF5", "DNAJC19", "DNM1L", "DNM2", "DPM1", "DPYSL5", "DST", "EARS2", "ECE1", "EFL1", "EHHADH", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "ELP1", "EMD", "ERAP1", "ESS2", "EXOC2", "EXOC6B", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "FANCD2", "FANCI", "FARSB", "FDPS", "FECH", "FIP1L1", "FKBP10", "FKBP14", "FLAD1", "FLII", "FLNC", "FMR1", "FOXRED1", "FSCN1", "FUS", "FXR1", "GALNT2", "GAPVD1", "GATAD2B", "GDAP1", "GGCX", "GLA", "GLB1", "GLMN", "GLUD1", "GNAI2", "GNAI3", "GOSR2", "GPT2", "GRHPR", "HADH", "HLA-A", "HLA-C", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HPRT1", "HS2ST1", "HTRA2", "IDH1", "IDH2", "IGBP1", "IGF2R", "ITCH", "KEAP1", "KIAA0319L", "KIF11", "KIF1A", "KIF20A", "KIF2A", "KMT2A", "L2HGDH", "LBR", "LMNB1", "LMNB2", "LNPK", "LONP1", "LSS", "MAGED2", "MAN2B1", "MATR3", "MCM4", "MECP2", "MED25", "MFN2", "MFSD8", "MGME1", "MINPP1", "MOGS", "MPG", "MSH2", "MSH6", "MSMO1", "MSTO1", "MTAP", "MTCH1", "MTMR2", "MTR", "MTX2", "MYH9", "NAGLU", "NANS", "NBN", "NCDN", "ND1", "NDUFA13", "NDUFA2", "NDUFA8", "NDUFAF1", "NDUFAF2", "NDUFB10", "NDUFB3", "NDUFS6", "NECAP1", "NEDD4L", "NEFL", "NEK9", "NNT", "NONO", "NPC1", "NR2F2", "NSD2", "NSUN2", "NT5C2", "NTHL1", "NUP107", "NUP133", "NUP88", "NUP93", "NXN", "OCLN", "OPA1", "OPA3", "P3H1", "PABPN1", "PAFAH1B1", "PCBD1", "PDCD6", "PDHX", "PEX11B", "PEX14", "PHGDH", "PIGK", "PIGL", "PIGS", "PIK3R2", "PITRM1", "PLOD3", "PMPCA", "PNPLA6", "PON2", "POP1", "POR", "PPOX", "PPP2R1A", "PPP2R1B", "PPT1", "PRCC", "PREPL", "PRPF3", "PRPF31", "PSAP", "PSMB4", "PTCD3", "PTRH2", "PUF60", "PURA", "PUS1", "PXMP2", "RABL3", "RAPGEF2", "RARS", "RBM10", "RBM8A", "RBMX", "RDX", "REEP2", "REPS1", "RINT1", "RNASEH2A", "RNF139", "RNF2", "RPS10", "RPS14", "RPS15A", "RPS6KA3", "RPSA", "RRAS2", "RREB1", "RTN2", "SAMHD1", "SAR1B", "SBDS", "SCARB2", "SCO2", "SDHB", "SEC23A", "SEC23B", "SEC31A", "SEPT9", "SFXN4", "SGPL1", "SIGMAR1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A4", "SLC25A42", "SLC2A1", "SLC33A1", "SLC35A3", "SMARCB1", "SMARCD2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SPART", "SPATA5", "SPECC1L", "SPOP", "SPR", "SPTBN1", "SPTLC1", "SPTLC2", "SRP54", 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sha256:657bab15aa0fce01502e4690352aeab4d33b8c908a17b1d6a232706f81f67096 +size 79883 diff --git a/msigdb_kegg/df_merge.tsv b/msigdb_kegg/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7e4fc5775d010ac8b9a7164f36452cc3801e9b96 --- /dev/null +++ b/msigdb_kegg/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Riboflavin metabolism 1 5 2.4740255482726 0.0133600142470642 1.2597087378640777 5.470873786407767 0.8651682051380694 0.3242718261444057 1.1073575266667028 1.2430881579904736 0.9666566709677474 0.2578857718572043 0.0464807950838554 0.0516364610584135 0.1008375048293403 0.027832231049335 0.0958131716431155 +Snare interactions in vesicular transport 8 15 2.2784760405550126 0.0226982304200911 5.803398058252427 13.6626213592233 0.8920027438628428 0.3386294703372389 3.103034547770364 2.9171839264116786 1.2201519782198902 0.3219991979242683 1.0 1.0 1.0 0.5767416823779237 0.0060226058745804 +Proteasome 7 34 2.119978941994866 0.0340078212030998 10.895631067961164 35.30825242718446 0.6639562464102341 0.4930746972205201 6.290791570409542 1.0118856061679289 1.2857516091435552 0.3675316845524202 1.0 1.0 0.0538434207197609 0.0003172858283449 7.632718264953843e-05 +Porphyrin and chlorophyll metabolism 3 12 1.9628508386180024 0.0496635085457524 3.728155339805826 13.315533980582524 1.2215621624941897 0.2689555702886888 1.770547470360957 1.4201912411596824 1.0389071586082248 0.2908939383930566 0.082934142330337 0.0919337377678228 0.0008717411361388 0.0011993766429203 0.0021733610219195 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6161b90a28931d541af1719d2f74cdc98d769400 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 180, + "title": "Average number of proteins per term", + "value": 15.477777777777778 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1c6358e6fc84956d2eb3336bf174d3eeff9cb3ef --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b8045eb54db4d914c415ce2474bb5a6f4ef9e9ce --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,74 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Renin angiotensin system 0.7897355168361612 2.516624112966515 0.0118485160869457 0.8829867910951699 0.1938848086954752 4 P52888,Q9UIQ6 2 +Riboflavin metabolism 0.8245088281664779 2.4740255482726 0.0133600142470642 0.91116825370843 0.2004002137059635 5 Q9NPH0 1 +O glycan biosynthesis 0.6941747572815511 2.2979999709087737 0.0215617907830576 0.9802297237902536 0.2431293831693009 3 Q86SF2,O43505 2 +Snare interactions in vesicular transport 0.6959460478539585 2.2784760405550126 0.0226982304200911 0.983961515638484 0.2431293831693009 15 O75396,Q12981,Q13277,O60499,Q9P2W9,O15400,Q13190,O14653 8 +Pentose and glucuronate interconversions 0.6373341960530586 2.2487999799894247 0.024525224658954 0.98854782875757 0.2452522465895401 2 Q7Z4W1 1 +Proteasome 0.5390446835426664 2.119978941994866 0.0340078212030998 0.998026442311003 0.2731459064165836 34 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Graft versus host disease 0.6535958130653214 2.0922131332112723 0.0364194541888778 0.9987415261885372 0.2731459064165836 3 P10321 1 +Allograft rejection 0.6535958130653214 2.0922131332112723 0.0364194541888778 0.9987415261885372 0.2731459064165836 3 P10321 1 +Autoimmune thyroid disease 0.6535958130653214 2.0922131332112723 0.0364194541888778 0.9987415261885372 0.2731459064165836 3 P10321 1 +Porphyrin and chlorophyll metabolism 0.680759845579851 1.9628508386180024 0.0496635085457524 0.9998957843244518 0.3575772615294173 12 P09601,P30519,P22830 3 +Cell adhesion molecules cams 0.6757408156293725 1.860720143865655 0.0627837076558883 0.9999914656718216 0.4036095492164252 11 Q92896 1 +Mismatch repair 0.5809496101133924 1.7520458276863309 0.0797659281001919 0.9999996825351578 0.463157001872082 17 P41440,Q9UQ84 2 +Glioma 0.5947708661806456 1.44738825621092 0.1477882130359178 0.9999999999996848 0.6901895911753573 11 O00459,P31751,Q13555,P62993,P05771 5 +Tight junction 0.4369354434379181 1.4428586327229778 0.1490602983248639 0.9999999999997592 0.6901895911753573 38 P16989,P63096,Q92797,P55196,P12814,Q16625,Q9Y2J2,P31751,P63151,P30154,P05771,P62070,P35579,P30153,P67870,P04899,P35580 17 +Fc epsilon ri signaling pathway 0.6174722900228199 1.419632273409925 0.1557147646086025 0.9999999999999414 0.6901895911753573 8 O00459,P31751,P05771,P07948 4 +Gap junction 0.5620453028040847 1.3395964958420674 0.1803765636781991 0.9999999999999996 0.719463840130881 12 P07437,Q9BVA1,P62993,P05771,Q9BUF5,P06493,P04899 7 +Leukocyte transendothelial migration 0.4663075978997998 1.2724410738373635 0.2032164482171743 1.0 0.719463840130881 21 O00459,P55196,P12814,Q16625,P05771,P63096,P04899 7 +Tryptophan metabolism 0.5043694542892543 1.2410207909624846 0.2145980684608406 1.0 0.719463840130881 16 Q9BWD1 1 +P53 signaling pathway 0.5313161356649234 1.23845631397491 0.2155469109304055 1.0 0.719463840130881 13 P14635,P31350,Q13794,P06493 4 +Aldosterone regulated sodium reabsorption 0.5585460807207886 1.202554465540958 0.2291487773407823 1.0 0.719463840130881 10 P05771,Q96PU5 2 +Melanogenesis 0.569982391126498 1.1886385232002854 0.2345819418008712 1.0 0.719463840130881 8 P05771,Q13555 2 +Vibrio cholerae infection 0.460931441055152 1.1761908013235045 0.2395186394970836 1.0 0.719463840130881 20 P24390,Q9Y487,Q93050,P05771,O43731 5 +Erbb signaling pathway 0.5275266032435039 1.15413644303182 0.2484442345534081 1.0 0.7202629959968561 12 O00459,P31751,P46108,Q13555,P05771 5 +Non small cell lung cancer 0.5544027857203249 1.14541356005589 0.2520378838050465 1.0 0.7202629959968561 9 O00459,P62993,P31751,P05771 4 +Lysine degradation 0.4270374211958985 1.1182341222755805 0.2634670144536257 1.0 0.7202629959968561 27 P30837,Q9BWD1 2 +B cell receptor signaling pathway 0.5468378723249311 1.1077573169833466 0.2679666382714081 1.0 0.7202629959968561 9 P07948,P31751,P05771,O00459 4 +Fatty acid metabolism 0.4125999169312946 1.0725605698940424 0.2834683240407161 1.0 0.7202629959968561 31 P49748,P23786,P30837,Q9BWD1 4 +Calcium signaling pathway 0.4789099427697422 1.0473865835449945 0.294921317015191 1.0 0.7202629959968561 15 P05771,P23634,Q13555,P21796 4 +Retinol metabolism 0.5217627411091603 1.0448855228618072 0.2960758815724933 1.0 0.7202629959968561 5 Q9BTZ2 1 +Chemokine signaling pathway 0.4355682566038621 1.0090820618060414 0.3129352801145004 1.0 0.7322024060357143 20 O00459,P07948,P31751,P46108,P04899,P05771 6 +Cardiac muscle contraction 0.4329044921041437 0.9915744681679242 0.3214051491447858 1.0 0.7322024060357143 20 P67936,P09669,P14406 3 +Mtor signaling pathway 0.4904682163552156 0.955219327325504 0.3394667938810101 1.0 0.7451710109583148 12 P31751,P23588 2 +Gnrh signaling pathway 0.5298048480315325 0.9412906112139856 0.3465559528077311 1.0 0.7507801090914729 6 P05771,Q13555 2 +Butanoate metabolism 0.4158606669633093 0.9313882049845406 0.3516527899604411 1.0 0.7507801090914729 21 Q9BWD1 1 +Phosphatidylinositol signaling system 0.5159631886219512 0.9258286194034884 0.3545350515154177 1.0 0.7507801090914729 8 Q8TBX8,P05771,Q10713 3 +Inositol phosphate metabolism 0.5031666735088558 0.8641600602041651 0.3874999693039584 1.0 0.7808188540002097 8 Q8TBX8,Q9UNW1 2 +Folate biosynthesis 0.4236245954692615 0.8547834676521324 0.3926710322345026 1.0 0.7808188540002097 3 P35270,P00374 2 +Nucleotide excision repair 0.4040186679069865 0.8520212805649217 0.3942022809305394 1.0 0.7808188540002097 21 P41440 1 +Prostate cancer 0.4797677683328574 0.8487534204311996 0.3960185139353696 1.0 0.7808188540002097 11 O00459,P31751 2 +Long term depression 0.4878278862969743 0.84465894735311 0.3983012866414055 1.0 0.7808188540002097 10 P07948,Q14344,P30154,P05771,P63096,P04899 6 +Apoptosis 0.42674996869445 0.8171258414151066 0.4138565166153718 1.0 0.7924912020294353 17 O00459,P31751,O95831,P17655 4 +Fc gamma r mediated phagocytosis 0.3887597609493681 0.8012966108363414 0.4229599524529011 1.0 0.7984462674610768 22 P07948,P50570,P31751,P46108,P05771 5 +Steroid hormone biosynthesis 0.4360039630068747 0.7585774262823197 0.4481053804856343 1.0 0.8065896848741417 4 Q53GQ0 1 +Type i diabetes mellitus 0.4295215857704909 0.7262615644172888 0.4676784370113327 1.0 0.8334863233865335 4 P10321 1 +Endocytosis 0.3415001533147686 0.711953837596545 0.4764933620692253 1.0 0.8387025551175742 41 Q96FZ7,Q96J02,P50570,Q9NRW7,Q6WKZ4,O00429,P20338,Q96PU5,Q8N6T3,P02786,P04439,P10321 12 +Oxidative phosphorylation 0.3147072378675026 0.7055789153880649 0.4804500401504059 1.0 0.8387025551175742 64 Q7KZN9,O95182,P00846,P51970,P00403,O75380,Q9Y5K8,Q9Y487,O75964,O43678,P03886,P13073,P14406,O43676,Q93050,O96000,P09669 17 +Progesterone mediated oocyte maturation 0.3667472726449009 0.6565112251158107 0.5114952475028485 1.0 0.8462915518173102 23 O00459,P63096,P53350,P31751,Q9UJX3,P06493,P14635,P04899 8 +Glycerolipid metabolism 0.4112728628001009 0.5854265452401364 0.5582609441002298 1.0 0.8746406151640498 13 P30837 1 +Dna replication 0.3497118314541975 0.5774335764606867 0.5636465977146385 1.0 0.8746406151640498 29 P41440,P49005,P33991,P25205 4 +Parkinsons disease 0.2965921256719784 0.5412821874509509 0.5883130960907974 1.0 0.8746406151640498 59 O95182,P00846,O43464,P51970,P00403,O75380,P21796,P45880,O43678,P03886,P13073,P14406,O43676,O96000,P09669 15 +Acute myeloid leukemia 0.4363482202955885 0.5360796081311233 0.5919035327157636 1.0 0.8746406151640498 7 O00459,P31751 2 +Endometrial cancer 0.4227024162703059 0.5098243887134437 0.6101744977189196 1.0 0.877481217037255 9 O00459,P31751 2 +Toll like receptor signaling pathway 0.4273244720607162 0.4972845320153023 0.6189884179578462 1.0 0.877481217037255 7 P31751 1 +Regulation of actin cytoskeleton 0.3132373308846737 0.4954866852931048 0.6202566183645564 1.0 0.877481217037255 42 O00459,Q14344,Q13576,P12814,Q96F07,P46108,Q9Y281,P35241,Q9UQB8,P62070,Q8TBX8,P35579,P15311,P35580,P41240 15 +Pathogenic escherichia coli infection 0.3487856817137905 0.4279787700579302 0.6686665769521849 1.0 0.9050514447204974 19 Q16625,P07437,Q9BUF5 3 +Thyroid cancer 0.4090137188650523 0.4209322229673986 0.673804574592261 1.0 0.9050514447204974 7 Q16204 1 +Chronic myeloid leukemia 0.3594782548056082 0.33390987310936 0.7384475693156363 1.0 0.93478308491326 13 O00459,P62993,P31751,P46108 4 +Natural killer cell mediated cytotoxicity 0.3567149059516229 0.2942074013118185 0.768599425373125 1.0 0.93478308491326 12 O00459,P05771,P04439,P10321 4 +Colorectal cancer 0.3514125365762822 0.2722956647455781 0.7853946893648793 1.0 0.9424736272378552 12 P31751 1 +Adherens junction 0.3036486498697768 0.2639188617786061 0.7918424411887708 1.0 0.943469042413494 23 Q9UQB8 1 +Pancreatic cancer 0.3504308190709387 0.2464102226531482 0.8053646936332064 1.0 0.943469042413494 11 P31751 1 +Neurotrophin signaling pathway 0.2973724974235742 0.2289191105776556 0.8189317868404431 1.0 0.9457670839086844 24 P31751,P46108,Q13555 3 +Abc transporters 0.3530759168175196 0.2279761188991271 0.8196648060541931 1.0 0.9457670839086844 9 Q03518,P08183 2 +Rna degradation 0.2903497488857313 0.2161181001703231 0.8288956911995986 1.0 0.9497777996003914 34 Q9GZS3,Q9UK45,Q96C86,Q9Y3B2,Q99547,Q9Y4Y9,Q5RKV6,P62310,Q96B26,P51003,Q9NQT5 11 +N glycan biosynthesis 0.2938650717441357 0.1894465895344082 0.8497428123581263 1.0 0.9549631866608562 21 O60476 1 +Melanoma 0.3436320799690169 0.1838112669956439 0.8541615169577659 1.0 0.9549631866608562 7 P31751 1 +Viral myocarditis 0.3316180042618585 0.1568527881870809 0.8753608687471643 1.0 0.9726231874968492 9 P04439,P35580,P10321 3 +Leishmania infection 0.3088522044460181 0.0874327126660954 0.9303275679851573 1.0 1.0 6 P05771 1 +Long term potentiation 0.3050940061409514 0.0852169279654214 0.9320889329636736 1.0 1.0 10 Q13555 1 +Rig i like receptor signaling pathway 0.2801457325055292 0.0670029026114315 0.94657939244555 1.0 1.0 5 Q7Z434 1 +Epithelial cell signaling in helicobacter pylori infection 0.2738105611099455 0.0629496667181538 0.9498065849158774 1.0 1.0 18 P07948,Q93050,Q9Y487 3 +Mapk signaling pathway 0.2558532544508589 0.0228349273063279 0.981781947320708 1.0 1.0 31 P31751,Q99956,Q9Y4G8 3 +Cytosolic dna sensing pathway 0.2617427923550338 0.001026724306275 0.9991807926717516 1.0 1.0 6 Q7Z434,P55265,Q9NZI8,O15160,Q13546 5 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..718a91d63513530aef168e5cba573524a06c4156 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTN1", "ACTN4", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGA", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALYREF", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEX1", "APRT", "AQR", "ARF6", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AURKA", "B3GAT3", "B4GAT1", "BAIAP2", "BAX", "BCAS2", "BCAT2", "BCKDHA", "BCKDHB", "BIRC6", "BLM", "BLVRA", "BNIP1", "BRCA1", "BUB1B", "BUB3", "BUD23", "BUD31", "CAB39", "CACYBP", "CAD", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CAPN2", "CARS", "CARS2", "CASK", "CBR1", "CCDC6", "CCNB1", "CD47", "CDC16", "CDC23", "CDC27", "CDC34", "CDC40", "CDC42", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDKN2A", "CETN2", "CFL1", "CFL2", "CHD8", "CHDH", "CHEK1", "CHERP", "CHMP2A", "CHMP6", "CHORDC1", "CHP1", "CHST14", "CKB", "CKMT1A*", "CLN5", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT9", "COMT", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPOX", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CS", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CXADR", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", 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"FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GCAT", "GCDH", "GCLC", "GGCT", "GGH", "GLA", "GLB1", "GLCE", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPI", "GPT2", "GRB2", "GRHPR", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HDAC1", "HDAC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HK1", "HK2", "HLA-A", "HLA-C", "HMGB1", "HMGCL", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", 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0.0039215884373549 15.264563106796116 64.83495145631068 0.939000341067099 0.4699320360831873 6.884300879212943 3.5957015529431366 1.0482386655891682 0.3835416044430508 0.3801575604193632 0.4130249240673272 0.0213556169291773 6.941601174933413e-05 4.7318803320597495e-06 +Intra golgi traffic 10 16 2.4394186979785006 0.0147109125066988 4.424757281553398 13.87135922330097 0.7636302424906817 0.4243971711811651 2.688824171738392 3.845367291797066 0.9598354803720488 0.3140361333882177 0.1664042855086975 0.1835089509173778 0.0614247268920475 0.0182997950486615 0.0036212839296716 +Cyclin a cdk2 associated events at s phase entry 8 42 2.436161117409535 0.014844071127861 13.196601941747574 42.85679611650485 0.6136168472607347 0.5150313285959647 7.221373891468615 2.098630488986879 1.3159566032429193 0.3694066609952225 1.0 1.0 0.175896893635733 0.002958524345255 0.0045099849487425 +Switching of origins to a post replicative state 14 58 2.4196434784471235 0.0155357305167174 16.810679611650485 58.20873786407767 0.6859740885709421 0.5709255515574044 8.560355820358037 3.2791073494099976 1.198149892515979 0.3860301174542495 1.0 1.0 0.1967082241040804 0.0010205325993841 1.144608165570603e-05 +Transport of small molecules 41 163 2.4194623569293783 0.0155434694098248 41.730582524271846 151.96601941747574 1.4265613612661356 0.380396759556163 14.87709311863932 12.598305121005488 1.746958952072276 0.4128488770716938 0.4879108573660617 0.5457531457684409 0.0101886176345373 4.610353517036176e-06 3.035322485886537e-07 +Antigen processing cross presentation 15 49 2.4144630034613463 0.0157584232412302 13.364077669902912 51.03883495145631 0.6606344305939695 0.5456453275819227 6.483621701094183 2.525298521609755 1.0422529083240153 0.3659829171921698 1.0 1.0 0.0377829414296325 0.0025565179770561 7.073536776167003e-05 +Synthesis of dna 19 81 2.3955823940702894 0.0165939842200772 23.16990291262136 82.84708737864078 0.4375997809997383 0.6204468538632794 11.716110681669798 5.49919819946737 1.2425112242470815 0.3782848222763735 0.398845479645601 0.4327036796546861 0.0260774389953396 0.0001217230774778 6.880552268825156e-07 +S phase 22 94 2.3779964973236667 0.0174069912672156 25.58252427184466 94.497572815534 0.3936025929765626 0.6471527110395977 12.311904628033766 6.6662819095148595 1.1799446716032989 0.3778079902664983 0.4977407158168507 0.5356345621372292 0.0656047650092995 0.0004513829051847 2.2397023084710663e-05 +Transport of inorganic cations anions and amino acids oligopeptides 3 10 2.372064821572713 0.0176889870665806 3.45873786407767 9.99514563106796 1.347451847228265 0.1988162564497566 2.1544143797408783 1.7967002462592632 1.0339867286779445 0.2465647399589519 0.173613373871201 0.1913705796369965 0.3467918934582977 0.0213813720021448 0.1611434930114498 +Heme biosynthesis 1 5 2.362965128438609 0.0181293754062159 1.616504854368932 5.298543689320389 0.3799926448994593 0.4874403957378427 1.1838391624700522 0.9657723985293564 0.9261555255993276 0.2942490709743225 1.0 1.0 0.1094892401774078 0.0328731354880699 0.1114297880404725 +Transcriptional regulation by runx2 9 48 2.362935624242818 0.018130818766449 16.021844660194176 51.64320388349515 0.5147340657969439 0.5490234274922848 8.286848189022676 3.0091087328640205 1.321202711135219 0.3758826947187164 1.0 1.0 0.2497932687322087 0.002894195016663 0.0086214897485596 +Cellular response to chemical stress 15 76 2.3574654848250183 0.0184001657364449 16.92233009708738 74.85436893203884 0.6393995551476427 0.564482392286313 7.443234134196828 3.8890130701767585 0.935566980068825 0.3664371412566685 0.4395171503297744 0.4752886178187883 0.0390712286884639 0.0003768289036047 6.727362196563217e-05 +Sting mediated induction of host immune responses 0 5 2.321033328457592 0.0202850451560088 2.262135922330097 6.036407766990291 -0.0301785213505694 0.5056398973526773 1.7788463865556277 0.5583737732194141 0.9710900078272215 0.3001381754391826 0.0423440523288004 0.0470522829573702 0.0921025797166938 0.2175647207167039 0.390305373111191 +Irf3 mediated induction of type i ifn 0 5 2.321033328457592 0.0202850451560088 2.478155339805826 5.233009708737864 -0.3059741337931244 0.5707238308572093 1.6076300156228986 0.4284513429828394 0.7439157051183788 0.2827483954530069 0.0340178825746634 0.0378187125466048 0.0743799864466655 0.1781979724676324 0.3268572232473809 +Metabolism of porphyrins 3 9 2.318848307683498 0.0204032628080763 2.766990291262136 9.186893203883496 1.2638611374915407 0.2204767139400954 1.3861582272503026 1.170645435718008 1.0950295956895657 0.2541910601955712 0.070936999678044 0.0786913117950012 0.0005309775927247 0.00062382482254 9.60684890252726e-05 +Orc1 removal from chromatin 12 49 2.3176534193766094 0.020468164478864 14.364077669902912 49.74757281553398 0.6917566411101944 0.5422658696614091 8.355189705990739 2.308567607855075 1.2721915859610031 0.3803308697876651 1.0 1.0 0.1290920553826253 0.0001621519489155 1.0740547566811618e-05 +Downregulation of erbb2 signaling 1 6 2.297682232894706 0.0215798815010503 2.104368932038835 6.106796116504855 0.1202031261869137 0.6071003154486625 1.5442597559951623 1.2020421245160804 0.7932629856141031 0.293315823503834 1.0 1.0 1.0 0.0693365470158766 0.214697112815727 +Assembly and cell surface presentation of nmda receptors 3 5 2.2694128184402484 0.0232432334017784 4.021844660194175 10.050970873786408 0.6119431771279947 0.4638365400303644 2.466672711798564 1.7830986526204615 1.029606868598912 0.3372268056856337 1.0 1.0 1.0 0.4972078859355511 0.1506847481690166 +Protein localization 21 78 2.262216652129762 0.0236840209750224 25.97087378640777 74.18203883495146 1.5594110758345356 0.2555609300308859 10.717199959161563 6.26233677332747 2.0947329132902324 0.3569924888492793 2.9974412898800404e-05 5.608080016760057e-05 6.361576956114066e-05 0.0023493338214379 1.0995003357092104e-06 +Downstream signaling events of b cell receptor bcr 8 38 2.2092828138486245 0.0271549758206153 13.109223300970871 42.81310679611651 0.5337893000107979 0.5120527765027618 7.35013455914348 2.784583610128895 1.330630298725885 0.3688632335833426 1.0 1.0 0.1487873266068847 0.0015979936813088 0.0020368548478273 +Runx1 regulates transcription of genes involved in differentiation of hscs 9 39 2.172827003557519 0.0297933401038825 11.74514563106796 40.9247572815534 0.4838158037368226 0.5501011058260618 6.5789160679611225 1.5190277579548277 1.1933646193238052 0.3604187581137549 1.0 1.0 0.1388614812827933 0.0012385676091947 0.0003721491072164 +The role of gtse1 in g2 m progression after g2 checkpoint 14 44 2.1720579234533197 0.0298512941704582 14.79611650485437 48.84466019417476 0.6226477470486884 0.5168095546238419 7.820323564061835 1.8499922936255029 1.3076695437390702 0.3722860732713196 1.0 1.0 0.1355867800667393 0.0011340341959979 0.0003258251621959 +Regulation of pten stability and activity 8 41 2.158273647763352 0.0309065623193625 12.611650485436892 41.82281553398058 0.6486618107800725 0.5229501310802542 7.056269001912706 2.1755846965350556 1.2659780846667748 0.3745012259374719 1.0 1.0 0.1226746045160812 0.0007830560056471 0.000795541851367 +Mitotic g1 phase and g1 s transition 18 76 2.1393878730780145 0.0324042682596736 22.104368932038835 76.02184466019418 0.5927262006732629 0.5705780900762646 11.678595487596883 5.354610434747646 1.3736272695770486 0.3846948779804449 1.0 1.0 0.400845832923264 0.0024735212605852 0.0001732678785335 +Regulation of signaling by cbl 3 6 2.132036317548444 0.0330038610825813 1.6771844660194175 4.276699029126213 -0.2552274244101926 0.5196690710450351 1.149150735358173 1.338794116403102 0.9419287734895342 0.3075453144867306 1.0 1.0 1.0 1.0 0.0531269764991638 +Cdt1 association with the cdc6 orc origin complex 8 39 2.126474306831443 0.0334637863764615 11.8373786407767 39.713592233009706 0.7088745358379469 0.5132999135100862 6.7665841522618235 1.8864642297262784 1.2345641700762902 0.3668156388656303 1.0 1.0 0.0949012099695084 0.0003015006992345 4.279797017838851e-05 +Asymmetric localization of pcp proteins 7 36 2.0910817288913406 0.0365207382687389 11.28883495145631 37.80825242718446 0.5764639774033125 0.5188050170985335 6.482730726459962 1.1863421199640956 1.2423982841678427 0.3682278814782295 1.0 1.0 0.0949012099695084 0.0018561414510811 0.0010063228921216 +Metabolism of polyamines 7 36 2.083512413232637 0.0372045414093611 11.783980582524272 38.49271844660194 0.5956280690899458 0.5058612771265996 6.813709458301494 1.1915745430318114 1.300721756016792 0.3709861514268986 1.0 1.0 0.0775813155228076 0.0009951056419778 0.0004103028700699 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 4 9 2.0825866460397857 0.0372889174840838 4.016990291262136 10.99757281553398 1.1239772251284714 0.2752182956921286 1.9514004604865949 1.181365809872934 1.0815649178051203 0.2865915409883788 0.0789520148513954 0.0875404472016038 0.014058804472369 0.0762921742488627 0.0116417512175889 +Mitochondrial protein import 10 36 2.080428746355357 0.0374862248623688 13.468446601941748 34.5873786407767 1.6025718162972953 0.1874419874946837 6.078090089851624 2.2108812815475147 1.8878681708577505 0.2901223460226844 0.0020596287369404 0.0028071579475431 0.0024373211620913 0.0029289523616429 0.0001005734989968 +Egr2 and sox10 mediated initiation of schwann cell myelination 1 6 2.0802949276010967 0.0374984897714854 1.5631067961165048 6.456310679611651 0.9405466898133904 0.3504222949879002 1.1919625891097876 1.444955732376159 0.8981851290078471 0.2877478182828594 0.082934142330337 0.0919337377678228 0.1758008751515455 0.0834574734746242 0.069181328144546 +Degradation of axin 7 35 2.0738123885532507 0.0380967381653287 11.135922330097088 36.5 0.6371703324335989 0.5044883973483546 6.515923056292238 1.1005294401076644 1.2875505119575097 0.3689236351245595 1.0 1.0 0.0775813155228076 0.0009951056419778 0.0004103028700699 +Dna replication 19 86 2.073375061401353 0.0381373879993096 24.50242718446602 88.36650485436893 0.2923135263536031 0.6312906600612657 12.317305449092803 5.805851117746023 1.1877285197942282 0.3655243748981305 0.4492572278358224 0.4854356723902606 0.0428059841697078 0.0004857227802637 8.56207346651452e-06 +Scf skp2 mediated degradation of p27 p21 7 40 2.070032762403296 0.0384492765149466 12.78883495145631 40.70873786407767 0.5921499036968256 0.5162943652980111 7.12520288261254 1.2647657441579598 1.3047123749289669 0.3686628673319737 1.0 1.0 0.0949012099695084 0.0018561414510811 0.0010063228921216 +Antigen processing ubiquitination proteasome degradation 16 82 2.066667824205989 0.0387654650297579 25.228155339805824 89.88592233009709 0.3040503636743611 0.5349081840989588 12.844717984151089 7.994482069951932 1.4235342488403817 0.383588489924638 0.6653399447083752 0.7045733708560526 0.0331776056462107 0.018618787305556 0.0583428588171107 +Cross presentation of soluble exogenous antigens endosomes 8 36 2.060105611279884 0.0393884455684074 11.097087378640778 36.91019417475728 0.6471378136535638 0.507052502601231 6.457500437861876 1.2421375880066114 1.2717860238430438 0.3672755762882163 1.0 1.0 0.0588586045542952 0.0004199381068154 1.8103742194584104e-05 +Ion channel transport 10 32 2.0573636102747925 0.0396512627831902 9.031553398058252 27.74271844660194 0.8980727715308076 0.3472480807052641 4.2752930421976005 3.4432740668393595 1.4212023690700646 0.3452897078102002 1.0 1.0 0.1862598674919939 0.0036501932708164 0.0018514914580574 +Regulation of ras by gaps 7 36 2.0521796799894334 0.0401522035119632 11.558252427184469 38.29611650485437 0.5949031665539309 0.5179046122727133 6.637200606991292 1.5039380235434 1.2829290056167597 0.3733028763215757 1.0 1.0 0.1039407380726692 0.0024554723849656 0.0014977097109146 +Degradation of dvl 7 36 2.0521796799894334 0.0401522035119632 11.50728155339806 37.79611650485437 0.5954952616194853 0.5106657090472662 6.536116642578212 1.2295647923796569 1.2774118860610646 0.3695881914917919 1.0 1.0 0.0832345551471358 0.0012377122057681 0.0005626054357481 +Hedgehog on state 8 40 2.05122410226259 0.0402451277532713 12.5752427184466 41.80339805825243 0.5567751925024539 0.5304257926517765 6.636298293339077 1.8972867972618663 1.2545866277969462 0.3643204702561447 1.0 1.0 0.1454623761357323 0.0068401475593005 0.0018268109851973 +Dna replication pre initiation 13 60 2.0421521514855656 0.0411364410937771 16.987864077669904 61.73300970873787 0.4288945668380205 0.5957541730468855 9.845276246498855 3.587542857888571 1.230696609236802 0.3684137615844171 1.0 1.0 0.2213471409258044 0.001707701287303 0.0001212134289169 +Signaling by the b cell receptor bcr 9 42 2.034105653784241 0.0419409440585425 14.0873786407767 45.66747572815534 0.5600618981864348 0.5194725240755018 7.669263829832862 3.2521255837555954 1.3165243686049508 0.3716278052198193 1.0 1.0 0.2178091494673695 0.0064725887331866 0.0042424291630432 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 2 5 2.029374267731186 0.0424201840049414 1.924757281553398 5.359223300970874 0.336977121900856 0.5615787693388659 1.3244044968153963 1.0273386196659136 0.8252392613858638 0.3024273388948905 1.0 1.0 1.0 0.5094216597603356 0.4115219783459027 +Regulation of hmox1 expression and activity 8 45 2.029009730360792 0.0424572992443648 12.524271844660197 45.58009708737864 0.7171016159839839 0.514573723238038 7.335701580194855 2.006274620945924 1.1938232298543638 0.3651188593292154 1.0 1.0 0.0181443698350236 0.000471503205235 0.0004030556375816 +Degradation of gli1 by the proteasome 8 39 2.027048127262192 0.0426574910236974 12.514563106796116 40.61407766990291 0.5405675752115602 0.5324758124461996 7.125251251124314 1.5545410691631658 1.272200728765061 0.3678115987415289 1.0 1.0 0.0919415891551245 0.0016834035897202 0.0001869989789037 +Stabilization of p53 7 37 2.025774108945821 0.0427879382906881 11.759708737864075 38.849514563106794 0.5626554032387434 0.5211156380328503 6.862945949053685 1.536505541452464 1.2546862993954295 0.3691198814060923 1.0 1.0 0.08610744549237 0.001374788533299 0.0006545278337592 +Regulation of runx3 expression and activity 7 36 2.0234396030802397 0.0430278445875464 11.46359223300971 36.730582524271846 0.6696914114866416 0.4949350431730664 6.642474003130895 1.4202887203012589 1.288769965462232 0.3632605735082652 1.0 1.0 0.0890100643743446 0.0015231541907095 0.0007583614663082 +G1 s dna damage checkpoints 7 39 2.013939454844806 0.0440158905183543 12.276699029126211 40.3252427184466 0.5620621733571898 0.5261130346169095 7.080750657966309 1.8659034848764728 1.2552712987328345 0.3710523646543767 1.0 1.0 0.1163398228410075 0.0034676048515423 0.0024345091408165 +Interleukin 1 signaling 7 40 2.0029046441158664 0.0451875245264661 13.79368932038835 46.30582524271845 0.5021606336105483 0.5332552544880472 7.891168652335007 2.7901813019255988 1.3195993763744758 0.3779352216468381 1.0 1.0 0.1862598674919939 0.0143895951598155 0.0169254538912603 +Cellular response to hypoxia 7 38 1.98962307579286 0.0466324722186199 12.067961165048544 40.00485436893204 0.522970313217548 0.5163863933875538 6.981963081004602 1.736242938617286 1.3015320227429066 0.3618367398400983 1.0 1.0 0.1100932826860655 0.0029289523616429 0.0019208853708131 +2 ltr circle formation 0 5 1.9833850565142768 0.0473244350272823 2.516990291262136 5.317961165048544 -0.7460036474006798 0.4230772547046059 1.4370961382542755 0.5646269654757307 0.8110523787380166 0.2878898717022174 0.0298283100591577 0.0331691185540615 0.0653907127050202 0.1577810442013011 0.2927037483377068 +Pcp ce pathway 8 48 1.9672432146132728 0.0491551781467987 13.383495145631068 48.61407766990291 0.2861400551198787 0.573085795011315 7.677259284018882 2.3137612538026593 1.2152839684208736 0.370148963517148 1.0 1.0 0.1724639155075248 0.0027518908513611 0.0041113362871812 +Negative regulation of notch4 signaling 7 38 1.965675270907581 0.0493361331252699 12.218446601941748 39.786407766990294 0.5856668642754154 0.5088435203982538 7.300807876201572 1.1247479582770583 1.3003786017754655 0.3684988575140048 1.0 1.0 0.0803922289273931 0.0011113418092766 0.0004815310793091 +Regulation of runx2 expression and activity 7 40 1.9632766527469836 0.04961403678741 13.184466019417476 42.609223300970875 0.5014097272359687 0.5334388394290158 7.623733474716015 1.80350585730159 1.3084091861848088 0.3700608446837968 1.0 1.0 0.1163398228410075 0.0034676048515423 0.0024345091408165 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..efe74c810961c9f0ef40a40528bc15f6e5e9a556 --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 1367, + "title": "Average number of proteins per term", + "value": 18.901243599122164 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..73be5c7cab5d8fb118c63cd48b16c2196617ded9 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..57b281fcc3d73ac0b12764ddb4b9519d64af526b --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,474 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Scavenging by class b receptors 0.9097379488838604 3.5920809703656458 0.0003280478808287 0.3614242826966793 0.0064389445028307 2 Q8WTV0 1 +Abacavir transport and metabolism 0.8906502749919172 3.505172134180752 0.0004563121508556 0.4641607515125201 0.00673239234063 2 P08183 1 +Ras activation upon ca2 influx through nmda receptor 0.8767389194435502 3.4412123138264903 0.000579113930291 0.5470067519843784 0.0068839021105036 2 Q13555 1 +Unblocking of nmda receptors glutamate binding and activation 0.8767389194435502 3.4412123138264903 0.000579113930291 0.5470067519843784 0.0068839021105036 2 Q13555 1 +Long term potentiation 0.8767389194435502 3.4412123138264903 0.000579113930291 0.5470067519843784 0.0068839021105036 2 Q13555 1 +Negative regulation of nmda receptor mediated neuronal transmission 0.8767389194435502 3.4412123138264903 0.000579113930291 0.5470067519843784 0.0068839021105036 2 Q13555 1 +Synthesis of leukotrienes lt and eoxins ex 0.8456810093820784 3.2964796549514763 0.0009790470539186 0.7378957380581801 0.010380141977371 2 P09960 1 +Amino acid transport across the plasma membrane 0.8789445599923382 3.1739222755597223 0.0015039395784297 0.8722184251521017 0.0140279506735334 3 P30825 1 +Interleukin receptor shc signaling 0.8188288579747671 3.1691193698519147 0.0015290158378613 0.8765308841789882 0.0140279506735334 2 O00459 1 +Signal regulatory protein family interactions 0.8188288579747696 3.1691193698519147 0.0015290158378613 0.8765308841789882 0.0140279506735334 2 Q08722 1 +Tie2 signaling 0.8188288579747671 3.1691193698519147 0.0015290158378613 0.8765308841789882 0.0140279506735334 2 O00459 1 +The activation of arylsulfatases 0.8107408605629264 3.1303416354101885 0.0017460311377315 0.9082704521833492 0.0152027042374458 2 O43681 1 +Cd28 dependent pi3k akt signaling 0.8627505141055662 3.100955499162997 0.0019289727783764 0.9285996368209046 0.0163782968201279 3 P31751 1 +Gap junction assembly 0.7984471044969299 3.0710231303984097 0.0021332662431945 0.9460279993839116 0.0174621254757301 2 Q9BUF5 1 +Transport of connexons to the plasma membrane 0.7984471044969299 3.0710231303984097 0.0021332662431945 0.9460279993839116 0.0174621254757301 2 Q9BUF5 1 +Endosomal vacuolar pathway 0.8362459546925343 2.9800290790251136 0.0028822102153793 0.9806617489601148 0.0218866917486772 3 Q9UIQ6,P10321 2 +Role of lat2 ntal lab on calcium mobilization 0.8190938511326793 2.900756512576687 0.0037226301425616 0.9938930688803844 0.0266431173030462 3 O00459,P07948 2 +Cytoprotection by hmox1 0.5209848954814736 2.8844011577973547 0.0039215884373549 0.995352149405468 0.0274913404813546 65 P49721,Q9UL46,Q99436,O43819,P09601,P30519,P20618,Q9BZK7,P28070,P13073,O00231,Q86X55,P28074,P09669,Q92530 15 +Carboxyterminal post translational modifications of tubulin 0.7987055016181168 2.805464213673382 0.005024416029467 0.9989776889903964 0.0316515055865502 3 Q14166,Q9BUF5 2 +Phosphorylation of emi1 0.7964401294498388 2.7948039786043934 0.0051931192886682 0.9991892015824406 0.0323903085778327 3 P14635,P53350 2 +Heme degradation 0.8462285529297717 2.7718193749950686 0.0055743958781171 0.9995199006181656 0.0338675518461606 4 P53004,P09601,P30519 3 +Erythropoietin activates ras 0.7873207453194235 2.7517430449862377 0.0059279013651174 0.9997047106126652 0.0346300904534852 3 P07948 1 +Signaling by erythropoietin 0.7873207453194235 2.7517430449862377 0.0059279013651174 0.9997047106126652 0.0346300904534852 3 P07948 1 +Gab1 signalosome 0.7314784859268879 2.739639914943361 0.0061506529284569 0.999782629272097 0.035619685673798 2 P62993 1 +Fceri mediated ca 2 mobilization 0.7789644012944932 2.71207632664501 0.0066863194784083 0.9998959764006768 0.037926135796615 3 P07948,P62993 2 +Rora activates gene expression 0.8180386526728449 2.6455010819447073 0.0081570026165436 0.999986275791449 0.0437648261167765 4 P50416,Q9BZK7 2 +Neurotransmitter clearance 0.6971853769006868 2.564321784905504 0.0103377653146945 0.999999322785494 0.0521465873992156 2 P21964 1 +Interleukin 15 signaling 0.6949207376253699 2.5526056929691774 0.010692046380301 0.9999995848917452 0.0537353948598219 2 P62993 1 +Bmal1 clock npas2 activates circadian gene expression 0.7886085468480017 2.5114494072132927 0.0120236519311087 0.999999934153781 0.0597684806902752 4 Q9BZK7 1 +Trafficking of myristoylated proteins to the cilium 0.7343042071197045 2.496635044980669 0.0125377918862212 0.9999999676778062 0.0609764982636279 3 P36405,A6NIH7 2 +Flt3 signaling 0.7317152103559497 2.4839653610536816 0.0129928445755025 0.999999982787194 0.062320065034077 3 P62993,P31751 2 +Antigen activates b cell receptor bcr leading to generation of second messengers 0.7792165749433445 2.4681949816747433 0.0135796328394455 0.9999999923652276 0.0644561044844514 4 P07948,P62993,Q13586 3 +Intra golgi traffic 0.7136622101467116 2.4394186979785006 0.0147109125066988 0.9999999984094742 0.0689270216796387 16 O00461,P83436,O60476,Q16706,Q9NRW7,Q9UP83,Q9Y2V7,Q13190,Q8TBA6,O14653 10 +Cyclin a cdk2 associated events at s phase entry 0.5361081798454612 2.436161117409535 0.014844071127861 0.9999999986777872 0.0689270216796387 42 P49721,Q9UL46,Q99436,P31751,P20618,P28070,P28074,Q92530 8 +Switching of origins to a post replicative state 0.4751876342370406 2.4196434784471235 0.0155357305167174 0.9999999994937756 0.0709786179197881 58 P49721,Q9UL46,Q99436,Q9Y619,P20618,Q13416,P28070,Q9UJX3,P33991,P25205,O00231,P28074,Q16763,Q92530 14 +Transport of small molecules 0.3957045543230894 2.4194623569293783 0.0155434694098248 0.9999999994991864 0.0709786179197881 163 Q9HD20,Q8TDW0,P49721,Q9UL46,Q70HW3,P30519,P21796,O15118,P04114,O00231,Q9UJZ1,P02786,Q9Y5K8,Q99436,Q9UHQ9,Q96TA2,Q13555,P28070,Q9Y487,Q96PU5,P45880,P23634,P28074,Q9Y6M7,Q92530,Q9C0H2,P28072,Q4KMQ2,P09601,P20618,P27105,Q99808,Q8WTV0,P08183,P30825,Q15758,P51790,Q9UEY8,Q10713,Q6PIU2,Q93050 41 +Activated tak1 mediates p38 mapk activation 0.6690391459074738 2.4174706136215707 0.0156287958989438 0.9999999995551462 0.0709786179197881 2 Q15750 1 +Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.6690391459074738 2.4174706136215707 0.0156287958989438 0.9999999995551462 0.0709786179197881 2 Q15750 1 +Antigen processing cross presentation 0.5109948587964945 2.4144630034613463 0.0157584232412302 0.9999999996284364 0.0713303462608003 49 P49721,Q9UL46,P28072,Q99436,Q03518,Q9UIQ6,P04439,P20618,O75396,P28070,Q9UBG0,O00231,P28074,P10321,Q92530 15 +Synthesis of dna 0.4614085856659717 2.3955823940702894 0.0165939842200772 0.9999999998836356 0.0738891740353279 81 P49721,Q9UL46,Q9BRT9,O00231,Q16763,Q99436,P41440,Q13416,P28070,P25205,P28074,Q92530,Q9NRF9,P20618,Q9UJX3,P49005,P33991,Q9Y619,Q9BRX5 19 +Irs mediated signalling 0.7619859335240433 2.3882367770176223 0.0169294307683423 0.9999999999270076 0.0748949251143169 4 O00459,P31751 2 +Regulation of innate immune responses to cytosolic dna 0.6619217081850554 2.379907053367633 0.0173170053500206 0.9999999999574232 0.0753017628553285 2 Q9NZI8 1 +S phase 0.4441246933990078 2.3779964973236667 0.0174069912672156 0.999999999962433 0.0753017628553285 94 P49721,Q9UL46,Q9BRT9,O00231,Q16763,Q99436,P41440,Q13416,P28070,P25205,P28074,Q92530,Q9NRF9,P28072,P20618,Q9UJX3,P49005,P33991,P31751,Q96FF9,Q9Y619,Q9BRX5 22 +Transport of inorganic cations anions and amino acids oligopeptides 0.7977892687953863 2.372064821572713 0.0176889870665806 0.9999999999746252 0.0760403940880997 10 Q70HW3,P30825,Q9Y6M7 3 +Heme biosynthesis 0.7994166453974458 2.362965128438609 0.0181293754062159 0.9999999999862538 0.0769715194215399 5 P22830 1 +Transcriptional regulation by runx2 0.5086237418795659 2.362935624242818 0.018130818766449 0.9999999999862814 0.0769715194215399 48 P49721,Q9UL46,Q99436,P31751,P20618,P28070,P14635,P28074,Q92530 9 +Cellular response to chemical stress 0.4622108059608729 2.3574654848250183 0.0184001657364449 0.9999999999905718 0.077156523195461 76 P49721,Q9UL46,Q99436,O43819,P09601,P30519,P20618,Q9BZK7,P28070,P13073,O00231,Q86X55,P28074,P09669,Q92530 15 +Runx3 regulates p14 arf 0.6557748301520592 2.347325644404767 0.0189087206307427 0.9999999999953572 0.0784107409474184 2 P42771 1 +Adrenaline noradrenaline inhibits insulin secretion 0.7006860306798233 2.3305586905169062 0.0197766418771574 0.9999999999986152 0.0787774338871137 3 P04899 1 +Metabolism of porphyrins 0.7985514706092804 2.318848307683498 0.0204032628080763 0.9999999999994224 0.0787888707871197 9 P09601,P30519,P22830 3 +Orc1 removal from chromatin 0.500071290939219 2.3176534193766094 0.020468164478864 0.9999999999994724 0.0788168474439636 49 P49721,Q9UL46,Q99436,Q9Y619,P20618,Q13416,P28070,P33991,P25205,O00231,P28074,Q92530 12 +Ptk6 regulates proteins involved in rna processing 0.6964401294498362 2.3093421444611764 0.0209246027533158 0.999999999999721 0.0798992512954826 3 O75525,Q07666 2 +Dap12 signaling 0.6954692556634117 2.3044831071930125 0.0211955395501612 0.9999999999998088 0.0807083636910041 3 O00459,P62993 2 +O linked glycosylation of mucins 0.6941747572815511 2.2979999709087737 0.0215617907830576 0.9999999999998854 0.0812663857078123 3 Q86SF2,O43505 2 +Downregulation of erbb2 signaling 0.8277127436432903 2.297682232894706 0.0215798815010503 0.9999999999998884 0.0812663857078123 6 P31751 1 +Grb2 sos provides linkage to mapk signaling for integrins 0.6447751536719599 2.288697139207053 0.0220969553631478 0.9999999999999456 0.0820829836451788 2 P62993 1 +Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.6447751536719541 2.288697139207019 0.0220969553631498 0.9999999999999456 0.0820829836451788 2 P63000 1 +Assembly and cell surface presentation of nmda receptors 0.7785388374349039 2.2694128184402484 0.0232432334017784 0.9999999999999892 0.0854914028746115 5 P07196,Q13555,Q9BUF5 3 +Constitutive signaling by overexpressed erbb2 0.7359619978534131 2.2659852425155877 0.0234522868163711 0.999999999999992 0.0854914028746115 4 Q96RT1 1 +Signaling by erbb2 ecd mutants 0.7359619978534131 2.2659852425155877 0.0234522868163711 0.999999999999992 0.0854914028746115 4 Q96RT1 1 +Signaling by erbb2 in cancer 0.7359619978534131 2.2659852425155877 0.0234522868163711 0.999999999999992 0.0854914028746115 4 Q96RT1 1 +Protein localization 0.4518899727091346 2.262216652129762 0.0236840209750224 0.999999999999994 0.0861065337044033 78 O15254,P46379,O60830,Q9NS69,Q5JRX3,P21796,Q99595,Q9BTZ2,Q9Y3D6,Q8N4H5,Q13011,Q9NR77,Q13505,O96011,O43681,Q13190,P09601,Q9NX63,Q9Y584,P62072,Q10713 21 +Fructose metabolism 0.637334196053063 2.248799979989449 0.0245252246589524 0.9999999999999982 0.088693074361873 2 Q00796 1 +Linoleic acid la metabolism 0.6366871562601113 2.2453216313339315 0.0247474923547545 0.9999999999999988 0.0890258474972356 2 O95864 1 +Creb phosphorylation 0.6334519572953776 2.2279082188406405 0.0258866360041436 0.9999999999999998 0.0919143673186087 2 P51812 1 +Downstream signaling events of b cell receptor bcr 0.5310792052928583 2.2092828138486245 0.0271549758206153 1.0 0.0956722988319101 38 P49721,Q9UL46,Q99436,P20618,P28070,P05771,P28074,Q92530 8 +Activation of nima kinases nek9 nek6 nek7 0.7202978310132796 2.191534573703111 0.0284131306468329 1.0 0.0995916656262067 4 P14635,P53350,P06493 3 +Signaling by ntrk2 trkb 0.6721884341016491 2.1871160253302113 0.0287340550522208 1.0 0.1004589597350022 3 P62993 1 +Hs gag biosynthesis 0.6247169200905902 2.1807117193481753 0.0292047456819659 1.0 0.1017083815642976 2 Q7LGA3 1 +Runx1 regulates transcription of genes involved in differentiation of hscs 0.5211558752172945 2.172827003557519 0.0297933401038825 1.0 0.1029078111385662 39 P49721,Q9UL46,Q99436,P20618,P28070,O00231,Q03164,P28074,Q92530 9 +Nod1 2 signaling pathway 0.669255663430405 2.1722150802559312 0.0298394437397984 1.0 0.1029078111385662 3 Q96J02,Q15750 2 +The role of gtse1 in g2 m progression after g2 checkpoint 0.4989245843847154 2.1720579234533193 0.0298512941704582 1.0 0.1029078111385662 44 P60900,P49721,Q9UL46,P28072,Q99436,P53350,P20618,Q9BVA1,P28070,Q9BUF5,O00231,P14635,P28074,Q92530 14 +Dap12 interactions 0.7160254740554775 2.1711155558655273 0.0299224384356739 1.0 0.1029078111385662 4 O00459,P10321 2 +Mastl facilitates mitotic progression 0.7134995144059613 2.1590204529252204 0.0308485802095157 1.0 0.1048368999765969 4 P30154,P14635,P06493 3 +Regulation of pten stability and activity 0.5083389100097659 2.1582736477633517 0.0309065623193625 1.0 0.1048368999765969 41 P49721,Q9UL46,Q99436,P31751,P20618,P28070,P28074,Q92530 8 +Adenylate cyclase inhibitory pathway 0.6647707767742668 2.14937809702565 0.0316044402581554 1.0 0.1069387867150953 3 P04899 1 +Mitotic g1 phase and g1 s transition 0.4421080817650457 2.1393878730780145 0.0324042682596736 1.0 0.1088369403218032 76 P07948,Q9NRF9,P49721,Q9UL46,P28072,Q99436,P31751,Q9Y619,P20618,P63151,Q13416,P28070,P33991,P25205,O00231,P14635,P28074,Q92530 18 +Signaling by egfr in cancer 0.661689627683165 2.133653951260637 0.0328711181341496 1.0 0.1089765171494896 3 P62993 1 +Constitutive signaling by ligand responsive egfr cancer variants 0.661689627683165 2.133653951260637 0.0328711181341496 1.0 0.1089765171494896 3 P62993 1 +Constitutive signaling by egfrviii 0.661689627683165 2.133653951260637 0.0328711181341496 1.0 0.1089765171494896 3 P62993 1 +Regulation of signaling by cbl 0.7894362296450503 2.1320363175484434 0.0330038610825813 1.0 0.1089765171494896 6 P07948,P46108,O00459 3 +Cdt1 association with the cdc6 orc origin complex 0.5153857481028777 2.126474306831443 0.0334637863764615 1.0 0.110228905967766 39 P49721,Q9UL46,Q99436,Q9Y619,P20618,P28070,P28074,Q92530 8 +Asymmetric localization of pcp proteins 0.5259777569325642 2.0910817288913406 0.0365207382687389 1.0 0.1194014540696581 36 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Metabolism of polyamines 0.5249995317818789 2.083512413232637 0.0372045414093611 1.0 0.1202215806621286 36 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.747253928053469 2.0825866460397857 0.0372889174840838 1.0 0.1202215806621286 9 Q13190,P46379,P09601,O43681 4 +Mitochondrial protein import 0.5246012177179057 2.080428746355357 0.0374862248623688 1.0 0.1202923558690696 36 Q8N4H5,O60830,Q9NS69,Q5JRX3,Q13505,Q9NX63,Q99595,Q9Y584,P62072,Q10713 10 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.7776274217847055 2.0802949276010967 0.0374984897714854 1.0 0.1202923558690696 6 Q9NR77 1 +Enos activation 0.6511131358666427 2.0794624933015022 0.0375748617089193 1.0 0.1202923558690696 3 P35270 1 +Degradation of axin 0.5284035408172427 2.0738123885532507 0.0380967381653287 1.0 0.1212414171978053 35 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Dna replication 0.4279218165652447 2.073375061401353 0.0381373879993096 1.0 0.1212414171978053 86 P49721,Q9UL46,Q9BRT9,O00231,Q16763,Q99436,P41440,Q13416,P28070,P25205,P28074,Q92530,Q9NRF9,P20618,Q9UJX3,P49005,P33991,Q9Y619,Q9BRX5 19 +Scf skp2 mediated degradation of p27 p21 0.5031355655466953 2.070032762403296 0.0384492765149466 1.0 0.121949329456919 40 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +O linked glycosylation 0.6943994820330247 2.0670194688774366 0.0387323194772748 1.0 0.1223842741239703 4 Q9Y2G5,Q86SF2,O43505 3 +Antigen processing ubiquitination proteasome degradation 0.4310877207944358 2.066667824205989 0.0387654650297579 1.0 0.1223842741239703 82 Q96J02,P49721,Q9UL46,Q99436,Q9UIQ6,P20618,P52888,Q05086,P28070,Q8WWI1,P55786,Q96PU5,O00231,P28074,Q16763,Q92530 16 +Cross presentation of soluble exogenous antigens endosomes 0.5219790608696843 2.0601056112798837 0.0393884455684074 1.0 0.1232128262975126 36 P49721,Q9UL46,Q99436,P20618,P28070,O00231,P28074,Q92530 8 +Ion channel transport 0.5392167207664679 2.0573636102747925 0.0396512627831902 1.0 0.123751772202331 32 Q9C0H2,Q9HD20,Q13555,P51790,Q9Y487,Q96PU5,P27105,P23634,Q93050,Q9Y5K8 10 +Regulation of ras by gaps 0.5209578183956647 2.0521796799894334 0.0401522035119632 1.0 0.1247455959110312 36 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Degradation of dvl 0.5209578183956647 2.0521796799894334 0.0401522035119632 1.0 0.1247455959110312 36 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Hedgehog on state 0.5008493077488587 2.05122410226259 0.0402451277532713 1.0 0.1247507701558321 40 P49721,Q9UL46,Q99436,P20618,P28070,O00231,P28074,Q92530 8 +Dna replication pre initiation 0.4377070916807137 2.0421521514855656 0.0411364410937771 1.0 0.1269379570546124 60 Q9NRF9,P49721,Q9UL46,Q99436,Q9Y619,P20618,Q13416,P28070,P33991,P25205,O00231,P28074,Q92530 13 +Signaling by the b cell receptor bcr 0.4879338793537656 2.0341056537842412 0.0419409440585425 1.0 0.128838810175343 42 P49721,Q9UL46,Q99436,P20618,P28070,P05771,O00231,P28074,Q92530 9 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.7259971219952511 2.029374267731186 0.0424201840049414 1.0 0.1295516251496578 5 O00459,P31751 2 +Regulation of hmox1 expression and activity 0.4796957982846101 2.0290097303607917 0.0424572992443648 1.0 0.1295516251496578 45 P49721,Q9UL46,Q99436,P09601,P20618,P28070,P28074,Q92530 8 +Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.6411003236245987 2.027852532018045 0.0425753010038354 1.0 0.129583978287543 3 P07900,P35270 2 +Degradation of gli1 by the proteasome 0.5030958084925999 2.027048127262192 0.0426574910236974 1.0 0.129583978287543 39 P49721,Q9UL46,Q99436,P20618,P28070,O00231,P28074,Q92530 8 +Stabilization of p53 0.5128387087616241 2.025774108945821 0.0427879382906881 1.0 0.1296920435551457 37 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Regulation of runx3 expression and activity 0.5172611757994193 2.0234396030802393 0.0430278445875464 1.0 0.1301306715733983 36 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +G1 s dna damage checkpoints 0.5014840953193485 2.013939454844806 0.0440158905183543 1.0 0.131374939603909 39 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Interleukin 1 signaling 0.4949944212214892 2.0029046441158664 0.0451875245264661 1.0 0.1335117689515073 40 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Cellular response to hypoxia 0.503458815631987 1.9896230757928597 0.0466324722186199 1.0 0.1365023330253822 38 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Pcp ce pathway 0.464355126158514 1.9672432146132728 0.0491551781467987 1.0 0.1423625604378683 48 P49721,Q9UL46,Q99436,P20618,P28070,P05771,P28074,Q92530 8 +Negative regulation of notch4 signaling 0.5004822890784545 1.9656752709075815 0.0493361331252699 1.0 0.142584553873666 38 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Regulation of runx2 expression and activity 0.4902122103833163 1.9632766527469832 0.04961403678741 1.0 0.1430852073594716 40 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Class i mhc mediated antigen processing presentation 0.398324277060417 1.9565615543228456 0.050399038818929 1.0 0.1447384161039412 104 P49721,Q9UL46,Q9NZ08,P55786,O00231,Q16763,Q99436,Q8WWI1,P28070,Q96PU5,P28074,Q92530,Q96J02,Q9UIQ6,P20618,P52888,Q9UJX3,Q9UBG0,Q03518,Q05086 20 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.7479580430946327 1.9489892502330903 0.0512967084928672 1.0 0.1463937380161786 6 P09601 1 +Transport and synthesis of paps 0.5816887738595997 1.94441812444592 0.051845049982671 1.0 0.1473434164788176 2 O43252 1 +Beta catenin independent wnt signaling 0.4522241638084 1.939707760761256 0.0524152158835122 1.0 0.1483469981630668 51 P49721,Q9UL46,Q99436,P20618,P28070,P05771,P28074,Q92530 8 +Dectin 1 mediated noncanonical nf kb signaling 0.4958266916445536 1.9281131231651376 0.0538410570211036 1.0 0.1517540720574199 38 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Tnfr2 non canonical nf kb pathway 0.4958266916445534 1.9281131231651376 0.0538410570211036 1.0 0.1517540720574199 38 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Unwinding of dna 0.7234516090083697 1.9234001036813804 0.0544298213295062 1.0 0.1530978719288786 8 P25205,Q9BRT9,Q9BRX5 3 +Transcriptional regulation by runx3 0.4791966186011776 1.914228539173276 0.0555909606896976 1.0 0.1560427993076316 41 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Platelet sensitization by ldl 0.6611890672669554 1.9047962024900804 0.056806567723417 1.0 0.1591282337662113 4 P04114,P30154 2 +Deadenylation dependent mrna decay 0.5030394514928224 1.878204092706775 0.0603532505013002 1.0 0.167009905739428 35 Q9GZS3,Q9UK45,Q96C86,Q9Y3B2,Q9Y4Y9,P23588,Q5RKV6,Q14240,P62310,Q969T7,Q96B26,P62312,Q9NQT5,Q13868,P11940 15 +Binding and uptake of ligands by scavenger receptors 0.7020527965642979 1.8692531092378168 0.0615876085118343 1.0 0.1697911236128436 9 Q5KU26,Q8WTV0 2 +Fceri mediated nf kb activation 0.4738802226939637 1.86911563592632 0.0616067280994663 1.0 0.1697911236128436 41 P49721,Q9UL46,Q99436,P20618,P28070,O00231,P28074,Q92530 8 +Striated muscle contraction 0.7279833995926179 1.859559131555879 0.0629479259548624 1.0 0.1725091753760322 6 P67936,Q9NYL9,P08670,P28289 4 +Signaling by notch4 0.4717808618040141 1.851252604746058 0.0641332210512286 1.0 0.1746416597151983 41 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Intra golgi and retrograde golgi to er traffic 0.4096230121173277 1.847897137685125 0.0646172246944867 1.0 0.1756098333148376 85 Q9UJW0,Q07866,Q6NUQ1,Q16706,Q14203,O75396,P11717,Q9BUF5,P40616,O14653,P52732,Q15102,O60476,P24390,Q13190,Q8N6T3,Q8TBA6,Q14746,Q12981,Q9UP83,Q9P2W9,Q9Y2V7,Q13561,O00461,P83436,O60664,Q92538,P20645,Q9NRW7,Q9BVA1,O60499,O43731 32 +Hedgehog off state 0.4614128223057655 1.8457296351289048 0.0649314719660789 1.0 0.1758676342356776 44 Q96J02,P49721,Q9UL46,Q99436,P20618,P28070,Q9BUF5,O00231,P28074,Q92530 10 +Sensing of dna double strand breaks 0.6416634426112087 1.808123289352514 0.0705873142280439 1.0 0.1884626143549533 4 Q92878 1 +Clec7a dectin 1 signaling 0.4599266127900114 1.7931251534586874 0.0729529144635321 1.0 0.1936439496536862 42 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Phase i functionalization of compounds 0.6068808304058123 1.787351945721492 0.0738806231944142 1.0 0.195005732488741 15 P07099,P30837,Q16850 3 +Abc transporter disorders 0.456445600797061 1.7817092514645545 0.0747966574422274 1.0 0.1962514985096446 43 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Defective cftr causes cystic fibrosis 0.4574317697896028 1.771415788647331 0.0764915849782994 1.0 0.1995496119567468 42 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Vegfr2 mediated cell proliferation 0.5893247560772918 1.7563653014306448 0.0790260536305222 1.0 0.2037123812696007 3 P05771 1 +Ret signaling 0.5881088542105694 1.7499005478114609 0.0801354761574058 1.0 0.2043753654984584 3 O00459 1 +Hedgehog ligand biogenesis 0.464461123553811 1.747480233369396 0.0805540707340659 1.0 0.2050603625576688 40 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Interleukin 1 family signaling 0.4531354530447003 1.733941827912736 0.0829284052630763 1.0 0.2087718784431405 42 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Apc c mediated degradation of cell cycle proteins 0.4175717015631416 1.7285710597967352 0.0838858929163772 1.0 0.2107941463542053 55 P49721,Q9UL46,Q99436,P20618,P28070,O00231,P14635,P28074,Q16763,Q92530 10 +Tcr signaling 0.4502454493895753 1.727110510172152 0.0841478183958355 1.0 0.2110643444901048 43 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Pp2a mediated dephosphorylation of key metabolic factors 0.5833838289765965 1.7247416464876535 0.0845740421092275 1.0 0.21174490029911 3 P30154 1 +Scavenging by class a receptors 0.6605319582372982 1.721374972556638 0.0851828027659187 1.0 0.2124822180024658 5 Q5KU26 1 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.4375477660352752 1.7205371414907478 0.0853348483418827 1.0 0.2124822180024658 48 P49721,Q9UL46,Q99436,P20618,P28070,O00231,P28074,Q16763,Q92530 9 +Iron uptake and transport 0.5645644331703403 1.715410498315464 0.0862699919729657 1.0 0.2137953910872129 18 P09601,P30519,Q9Y487,Q93050,P02786 5 +G2 m dna replication checkpoint 0.5810579100717879 1.7123358275031983 0.0868347977546384 1.0 0.2146531076502545 3 P14635 1 +Adp signalling through p2y purinoceptor 12 0.6204622512273967 1.702124772760281 0.0887319809324231 1.0 0.2169885830673032 4 P04899 1 +Gaba receptor activation 0.6204622512273967 1.702124772760281 0.0887319809324231 1.0 0.2169885830673032 4 P04899 1 +Gaba b receptor activation 0.6204622512273967 1.702124772760281 0.0887319809324231 1.0 0.2169885830673032 4 P04899 1 +Mitotic g2 g2 m phases 0.4014447940380257 1.6960913859959084 0.0898685747178977 1.0 0.2189845662020788 78 P49721,Q9UL46,Q9BUF5,O00231,P60900,Q99436,P07437,P28070,P28074,Q92530,P28072,O94927,P20618,P63151,P14635,Q13561,Q9H6D7,P53350,Q9BSJ2,Q9BVA1,P06493 21 +Ub specific processing proteases 0.404279917678646 1.6891194774919285 0.0911965359458475 1.0 0.2214698742764475 66 Q9NZL9,Q9HBM6,Q9UL46,P49721,Q99436,P21796,P20618,P28070,P45880,O00231,P28074,Q96K76,Q92530 13 +Mismatch repair 0.6527205067970069 1.676792543475293 0.0935830563509998 1.0 0.2260983910613205 10 Q9UQ84 1 +Ctla4 inhibitory signaling 0.6876588439305561 1.6766293256206843 0.093614988544775 1.0 0.2260983910613205 6 P31751 1 +Signal amplification 0.6500221897321561 1.6710732744038057 0.0947072054849313 1.0 0.2283328922361573 5 P04899,Q14344 2 +Retrograde transport at the trans golgi network 0.5671595160489903 1.6699115020939257 0.0949368742938405 1.0 0.2284324564466528 17 P83436,Q14746,O60664,P20645,P11717,Q9UP83,O60499,Q9Y2V7,P40616 9 +Signaling by notch 0.4004071402149907 1.657197885932035 0.097479473833101 1.0 0.2333702990014871 58 P49721,Q9UL46,Q99436,P67809,P20618,Q9BZK7,P28070,O00231,P28074,Q92530 10 +Regulation of tp53 expression and degradation 0.656559283976861 1.6499807018355686 0.0989468831807971 1.0 0.2349493920147726 9 P31751,P30154,P42771,P06493,Q93009 5 +Platelet aggregation plug formation 0.645401554404144 1.6488893794433457 0.0991702993361549 1.0 0.2349493920147726 5 P18031,P46108,P41240,P62993 4 +Integrin signaling 0.645401554404144 1.6488893794433457 0.0991702993361549 1.0 0.2349493920147726 5 P18031,P46108,P41240,P62993 4 +Mrna decay by 3 to 5 exoribonuclease 0.5820926910773258 1.6464563025650047 0.0996698495470234 1.0 0.2350734953567659 15 Q9GZS3,Q96C86,Q9Y3B2,Q5RKV6,Q969T7,Q96B26,Q9NQT5 7 +Stimuli sensing channels 0.6428337247133756 1.6276563138779876 0.1035977811461892 1.0 0.2431924692381546 10 Q9C0H2,P27105,P51790,Q96PU5 4 +Transcriptional regulation by runx1 0.3977486700707908 1.6225647687214677 0.1046824770077221 1.0 0.2442370791949768 70 P49721,Q9UL46,Q99436,Q16625,P20618,Q15291,Q9HCL2,P28070,P05771,O00231,Q03164,P28074,Q92530 13 +Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.5247492720802391 1.6224896019418693 0.1046985577236696 1.0 0.2442370791949768 2 P11802 1 +Ptk6 regulates cell cycle 0.5247492720802391 1.6224896019418693 0.1046985577236696 1.0 0.2442370791949768 2 P11802 1 +Fc epsilon receptor fceri signaling 0.4274170776635403 1.6031013320916232 0.1089122839743643 1.0 0.2523442240558577 47 O00459,P07948,P60900,P49721,Q9UL46,P28072,Q99436,P20618,P28070,O00231,P28074,Q92530 12 +C type lectin receptors clrs 0.430877783213233 1.5926486541390008 0.111239032197318 1.0 0.2565178051898046 45 P49721,Q9UL46,Q99436,P20618,P28070,O00231,P28074,Q92530 8 +Hdr through homologous recombination hrr 0.4918876272166604 1.5913685874270085 0.1115266494182429 1.0 0.2565178051898046 27 P41440,Q9UQ84 2 +Class a 1 rhodopsin like receptors 0.6689622731273205 1.590812135294356 0.1116518610738359 1.0 0.2565178051898046 6 P42892 1 +Peptide ligand binding receptors 0.6689622731273205 1.590812135294356 0.1116518610738359 1.0 0.2565178051898046 6 P42892 1 +Gpcr ligand binding 0.6517616654726579 1.5848375203412133 0.1130032551662885 1.0 0.2591869963293899 8 P42892 1 +Neddylation 0.393706727766801 1.5796507014626002 0.1141868812701123 1.0 0.2601557778270726 71 P49721,Q9UL46,Q9Y5A7,Q99436,P20618,Q15291,Q8WWI1,P28070,O00231,P28074,Q9BTE7,Q92530 12 +Dna strand elongation 0.4942072018795916 1.5733895186462818 0.1156286524741094 1.0 0.2625653952360592 25 P41440,Q9BRX5,Q9BRT9,P25205,P49005 5 +G2 m checkpoints 0.3888481765520362 1.568867594320872 0.1166787941315434 1.0 0.2636362174839999 81 Q9NXR7,P49721,Q9UL46,Q99436,Q9Y619,P20618,Q9UQ84,P28070,P25205,P14635,P28074,Q92530 12 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.6393380362133774 1.5659069191076922 0.1173704097986685 1.0 0.2643251238793737 9 P49366,P38435,O43681,O60725 4 +Pink1 prkn mediated mitophagy 0.6473254155660013 1.5635661983707592 0.1179194781290107 1.0 0.2651248792801935 8 Q8N4H5,P21796,Q9NS69 3 +Cholesterol biosynthesis 0.5489584653589499 1.5606926846293032 0.1185962781280909 1.0 0.2656914977860536 17 Q9BWD1,P48449,Q15392,Q16850,Q15800 5 +Synthesis of pa 0.6345820796876299 1.5425960783190178 0.1229288101545522 1.0 0.273596269644249 9 Q9NPH0 1 +Post chaperonin tubulin folding pathway 0.6504240930366406 1.5401869403143909 0.1235147923322714 1.0 0.2740985732438556 7 Q9BVA1,Q99426,O75347,Q9BUF5 4 +Class b 2 secretin family receptors 0.5101908767389256 1.538680017445159 0.1238824330220316 1.0 0.2744688588997037 2 P63218 1 +Rhoa gtpase cycle 0.4305715366237835 1.5354031779219068 0.12468482360244 1.0 0.2750926842095202 42 O00459,Q96HY6,Q9Y4F1,P41440,P51572,O15173,P30519,P27105,Q13190,P02786,Q96RT1 11 +Tcf dependent signaling in response to wnt 0.3888862298623618 1.532189981043387 0.1254755601805584 1.0 0.2757445214740812 59 P49721,Q9UL46,Q99436,P31751,P20618,Q15291,P28070,P28074,Q92530 9 +Degradation of beta catenin by the destruction complex 0.4201219013741968 1.5142872026177276 0.1299530128969717 1.0 0.2845432164486081 46 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Dna double strand break repair 0.3962267099645845 1.5117873476966524 0.1305879691239737 1.0 0.2847109310884722 55 Q9UNS1,P41440,P12956,Q9UQ84,P49005 5 +Regulation of kit signaling 0.5822927494066281 1.508846290290616 0.1313380680654359 1.0 0.2856235209483726 4 P07948 1 +Polo like kinase mediated events 0.5822265255185377 1.5085085144425103 0.1314244291708313 1.0 0.2856235209483726 4 P14635 1 +Diseases of signal transduction by growth factor receptors and second messengers 0.338234068193295 1.4924733919526405 0.1355750875884416 1.0 0.2918600704462987 134 P49721,Q9UL46,O95429,Q07866,Q99956,P35269,Q9BZK7,O00231,Q92734,P84095,O43815,O00459,P60900,Q99436,P67936,Q13555,Q9NRY5,P62993,P28070,Q8WWI1,P28074,Q92530,P28072,P20618,O94979,P07948,P31751,Q6WCQ1,P52298,Q96RT1 30 +Signaling by erbb2 0.6000464585731446 1.474702594848425 0.1402925181622889 1.0 0.299656050512264 11 P31751 1 +Cd28 co stimulation 0.6192289362209495 1.467095433587071 0.1423500961824519 1.0 0.3026323195667369 9 P07948,P31751,O00459 3 +Uch proteinases 0.4180526212729392 1.4572846829556594 0.1450378131318999 1.0 0.3064400163080482 44 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Metabolism of steroids 0.4108143305636131 1.448346777062382 0.147520091643974 1.0 0.3097695319159947 47 Q9BZF3,Q9BWD1,Q53GQ0,P48449,Q15392,Q9BZK7,Q9HCL2,Q86X55,Q16850,P38435,Q15800 11 +Anchoring of the basal body to the plasma membrane 0.4739843388512347 1.4451408195976885 0.1484183353078723 1.0 0.3107011705449639 26 Q7Z4H7,P61981,P53350,Q15019,O94927,P07437,Q14203,Q7Z460,Q9H6D7,P41208,P06493,P30153,Q13561,P61163 14 +Cdc6 association with the orc origin complex 0.5680260615993906 1.4359104785810015 0.1510278163979115 1.0 0.3142390030684095 4 Q9Y619 1 +Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.5990344962192364 1.424210072155375 0.1543856701021675 1.0 0.3207374027806429 5 Q8NB78,Q9BZK7 2 +Interleukin 7 signaling 0.52599297941872 1.414983104198867 0.1570734499246509 1.0 0.3227860919696647 3 O00459 1 +Metabolism of fat soluble vitamins 0.6303988725079005 1.412112659746824 0.1579167917316324 1.0 0.3235043098332953 6 P04114,Q8N0U8 2 +Insulin receptor signalling cascade 0.5964406555164201 1.4115447942276969 0.1580840372850338 1.0 0.3235043098332953 5 O00459,P31751 2 +Adaptive immune system 0.3309340621999688 1.3959527153309486 0.1627287346493326 1.0 0.3305351861302196 168 Q9UJW0,P49721,Q9UL46,Q07866,O75396,Q9NZ08,P55786,Q9BUF5,O00231,P52732,Q16763,P10321,O00459,P60900,Q99436,Q9BXS5,Q8WWI1,P28070,Q96PU5,P28074,Q5KU26,Q92530,Q96J02,P28072,P50570,Q9UIQ6,P20618,P52888,Q9UJX3,Q9UBG0,Q13561,P05771,P07948,Q03518,P31751,P51572,Q05086,P04439 38 +Signaling by hedgehog 0.3912327068395215 1.3760020255669052 0.1688210061562116 1.0 0.3399560781749581 52 Q96J02,P49721,Q9UL46,Q99436,P20618,P28070,Q9BUF5,O00231,P28074,Q92530 10 +Polymerase switching 0.5422749184600859 1.371373720094096 0.1702584854159763 1.0 0.3422696317112347 14 P41440 1 +Rhof gtpase cycle 0.5151944732707608 1.3560348488669762 0.1750880803371095 1.0 0.3504325121827654 17 O00459,Q9Y4F1,P20700,Q5JTV8,P12814,Q9UEY8,P80723,Q9Y6M7 8 +Costimulation by the cd28 family 0.5507235803204956 1.3457913776384898 0.1783698069282846 1.0 0.355958432220387 13 O00459,P07948,P31751,P30154,P62993,P30153,P41240 7 +Slc mediated transmembrane transport 0.4593048666518998 1.3250827077844305 0.1851437208260447 1.0 0.3662684028497874 25 Q70HW3,P30825,Q9Y6M7 3 +Heme signaling 0.595968374182812 1.3152523394952045 0.1884251101019614 1.0 0.3716841637942009 8 P04114,Q9BZK7,P09601 3 +Inhibition of replication initiation of damaged dna by rb1 e2f1 0.6073858114674542 1.3046245995988102 0.1920207075783029 1.0 0.3782309902875217 6 P49643,P49642,P30154,P30153,Q14181 5 +Nephrin family interactions 0.5915721231766666 1.2938596430668032 0.1957139065683997 1.0 0.3843978595962678 8 O00459,Q13813,P46940,P12814,Q01082,Q9Y5K6,O14936 7 +Recruitment of numa to mitotic centrosomes 0.4460121934343354 1.2905009888233132 0.1968767687321362 1.0 0.3858507730788235 29 Q7Z4H7,P61981,P53350,P06493,O94927,P07437,Q9BSJ2,Q14203,Q7Z460,Q9BVA1,Q9H6D7,Q9BUF5,P41208,P30153,Q13561,P61163 16 +G alpha s signalling events 0.5713136119137228 1.2884691735288918 0.1975826928713799 1.0 0.3858507730788235 5 P04899 1 +Nrage signals death through jnk 0.53721435511001 1.277445416169575 0.2014450394157352 1.0 0.3928321952657775 4 Q92974,Q14344 2 +Interleukin 3 interleukin 5 and gm csf signaling 0.5870859335866712 1.2720149462487575 0.2033678088675938 1.0 0.3934251730488503 8 P07948,P46108,O00459 3 +Caspase mediated cleavage of cytoskeletal proteins 0.5361027670873038 1.2717106906705613 0.2034759307575253 1.0 0.3934251730488503 4 P08670 1 +Auf1 hnrnp d0 binds and destabilizes mrna 0.4088238597019344 1.2695349441967174 0.2042503355212699 1.0 0.393909276981473 40 P49721,Q9UL46,Q99436,P20618,P28070,P28074,Q92530 7 +Programmed cell death 0.3550372109159018 1.2693882721550729 0.2043026169567405 1.0 0.393909276981473 94 P49721,P08670,Q9UL46,Q99436,P41440,Q16625,P31751,P20618,P28070,Q13794,P28074,Q92530 12 +Abc family proteins mediated transport 0.3778453873802632 1.2677993290787246 0.2048696218525636 1.0 0.3944461592569781 53 P49721,Q9UL46,Q99436,P20618,P28070,P28074,P08183,Q92530 8 +Organic anion transporters 0.461339372371403 1.2542254470193293 0.2097600730373208 1.0 0.4004776813435999 2 Q9H936 1 +Ion transport by p type atpases 0.5329882253872185 1.2477160293933234 0.2121350690168777 1.0 0.4041275778600433 13 Q9HD20,Q13555 2 +E2f enabled inhibition of pre replication complex formation 0.592539929689003 1.2350669061304342 0.2168056046966742 1.0 0.4087907056832464 6 Q13416,P14635,Q9Y619 3 +Golgi associated vesicle biogenesis 0.4447019441165751 1.2334797808255222 0.2173968157309072 1.0 0.408942328538725 26 P50570,Q9H3P7,P11717,O75976,Q8NC96 5 +G alpha z signalling events 0.5921514212415201 1.2332451220764746 0.2174843254189122 1.0 0.408942328538725 6 P05771 1 +Regulation of mrna stability by proteins that bind au rich elements 0.3600462447893936 1.2266759909791831 0.2199443950497688 1.0 0.4124334540919533 58 P49721,Q9UL46,Q9Y3B2,Q99436,P20618,Q96B26,P28070,P28074,Q92530 9 +Polymerase switching on the c strand of the telomere 0.5012422386324011 1.2223389471968311 0.2215794766765282 1.0 0.4133680376796888 16 P41440 1 +Rho gtpase cycle 0.3213063096678227 1.2188207103875208 0.2229122490958341 1.0 0.4151512868038219 144 Q9Y4F1,Q13576,Q9Y266,P30519,P50402,P62995,P02786,Q8IZP0,P84095,O00459,Q96CS3,Q14126,Q15904,P20700,Q14344,P41440,P67936,O15173,Q13505,P62993,Q9UQB8,Q13190,P80723,P07910,Q9Y6M7,Q92974,P38159,Q96HY6,Q9BX68,Q9NYL9,Q6IAA8,P08670,Q86XL3,P12814,Q96F07,P42167,Q03001,O75976,P27105,Q9P0I2,Q99707,Q15758,Q5JTV8,P51572,Q7Z6E9,Q9UEY8,Q9BT78,P62070,Q07065,P78371,Q96RT1 51 +Response of eif2ak1 hri to heme deficiency 0.4898791612954465 1.2171742353641386 0.2235379307563225 1.0 0.4152324846615709 3 P05198 1 +Nuclear receptor transcription pathway 0.454868974441926 1.2163093230859578 0.2238671113354629 1.0 0.4152324846615709 2 Q15648 1 +Mapk6 mapk4 signaling 0.3839397677038186 1.1776042175620725 0.2389544276915394 1.0 0.4361157578829565 46 P49721,Q9UL46,Q99436,Q16181,P20618,P28070,P28074,Q92530 8 +Dcc mediated attractive signaling 0.4480750566159797 1.1764760297909629 0.2394047055355548 1.0 0.4362010897368025 2 P63000 1 +Recruitment of mitotic centrosome proteins and complexes 0.4367645933610126 1.1758886631380243 0.2396393697090992 1.0 0.4362010897368025 26 Q7Z4H7,P61981,P53350,O94927,P07437,Q9BSJ2,Q14203,Q7Z460,Q9H6D7,P41208,P06493,P30153,Q13561,P61163 14 +Gpvi mediated activation cascade 0.5797216522878404 1.1749369172928992 0.2400199545321917 1.0 0.436312869475407 6 P07948,P84095 2 +Epha mediated growth cone collapse 0.5730525895294467 1.172144917072905 0.2411388789598154 1.0 0.4371841479284718 7 P07948,P35580,Q15375 3 +Cyclin a b1 b2 associated events during g2 m transition 0.5574444178741103 1.1605567786080384 0.2458221909150602 1.0 0.4444959457419143 9 P53350,P63151,P30154,P06493,P14635 5 +Rho gtpases activate iqgaps 0.5639701541022683 1.1593119101992806 0.2463290687082855 1.0 0.4448240910491761 8 P35221,Q13576,P35222,P63000,Q9BVA1,Q9BUF5 6 +Metabolism of cofactors 0.5405399810598078 1.137172306970601 0.2554662613466014 1.0 0.4588993157172196 5 P35270,O75874,P07900 3 +Lipophagy 0.5070828660025776 1.1218190640526304 0.2619393787749533 1.0 0.4680668376279231 4 O60664 1 +Cell surface interactions at the vascular wall 0.4749658068574282 1.110156154097704 0.2669317429674094 1.0 0.4751245997870425 17 P07948,O00459,Q08722,P04114,Q92896 5 +Ra biosynthesis pathway 0.5024393901563017 1.0978358387508722 0.272276178889939 1.0 0.4815026345957913 4 Q9BTZ2 1 +Lagging strand synthesis 0.4705990890035862 1.0834467477066616 0.2786101755444785 1.0 0.4907709553192632 17 P41440 1 +Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.5285204671720596 1.078075659830961 0.2809999928731277 1.0 0.4937364913336318 5 Q13555 1 +Pi3k akt signaling in cancer 0.5464417725286729 1.0738430022303225 0.2828930529237907 1.0 0.4964246512796174 8 O00459,P31751,P84095,O43815 4 +Apoptosis 0.3463884776242799 1.0665205003604108 0.2861884166086375 1.0 0.5009213386735051 82 P49721,P08670,Q9UL46,Q99436,Q16625,P31751,P20618,P28070,Q13794,P28074,Q92530 11 +Recognition of dna damage by pcna containing replication complex 0.4667415899458829 1.059863770975738 0.2892065797347487 1.0 0.5043872748082859 17 P41440 1 +Negative regulation of the pi3k akt network 0.5078118858789689 1.0481530489955784 0.2945680982915211 1.0 0.5103606975469066 12 O00459,P31751,Q8TBX8,P84095,O43815 5 +Rac3 gtpase cycle 0.4090351157676682 1.0451519893154753 0.2959527288901293 1.0 0.5114631863373031 31 O00459,Q6IAA8,Q15758,O15173,Q9UQB8,P02786,Q96RT1 7 +Signaling by erbb4 0.5513998366073811 1.042133086541616 0.2973499806143724 1.0 0.5132290700755646 6 Q96J02 1 +Activation of bh3 only proteins 0.5062282564552117 1.039651007678993 0.2985020698284004 1.0 0.5132733703841804 12 Q13794 1 +Cell cycle checkpoints 0.3098054116680562 1.035520608225336 0.3004258472680063 1.0 0.5152849852137574 138 P49721,Q9UL46,Q6P1K2,Q9UQ84,O00231,Q53HL2,Q16763,Q99436,Q13416,P28070,P25205,P28074,Q92530,P20618,Q96EE3,Q9UJX3,P14635,P33991,Q9NXR7,Q96IY1,Q6IPU0,Q9Y619,P57740 23 +Mapk family signaling cascades 0.3443920103707429 1.0255529122232907 0.3051023724942809 1.0 0.5219961742173743 77 O00459,P49721,Q9UL46,Q99436,Q16181,Q99956,Q13555,P20618,O60725,P28070,Q9Y4G8,O00231,Q96P70,P28074,P07196,Q92530 16 +Trna modification in the nucleus and cytosol 0.5292745485929927 1.0204458966897043 0.3075170361307671 1.0 0.5248137183405226 9 Q9H974,Q08J23,Q5VV42 3 +Pi metabolism 0.4591885113029885 1.0137355338702525 0.3107089636472255 1.0 0.5295999417777523 17 Q13614,Q8TBX8,Q8IY17 3 +E2f mediated regulation of dna replication 0.5009768577461918 1.0114778243480171 0.3117877895503831 1.0 0.5307769717501541 12 P49642,Q9Y619,Q13416,P30154,P06493,P14635 6 +Termination of translesion dna synthesis 0.4579949278696933 1.006453486955265 0.3141974754388428 1.0 0.5338369363509943 17 P41440 1 +Deubiquitination 0.3399214044271752 0.9926493667545436 0.3208808579651576 1.0 0.5427531223332317 83 Q9NZL9,P49721,Q9UL46,Q9HBM6,Q8NB78,P21796,O00231,Q96K76,Q15388,P60900,Q99436,Q7Z434,P28070,P45880,P28074,Q92530,P28072,P20618,Q9NXR7 19 +Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.4407094032421628 0.9916093631658088 0.321388120023836 1.0 0.5427531223332317 19 P41440 1 +Signaling by kit in disease 0.5392351011379117 0.9852535977389422 0.3244995193063604 1.0 0.546294141492358 6 P07948,O00459 2 +Aurka activation by tpx2 0.4102915522170322 0.9839079006415176 0.3251607987206413 1.0 0.5467340859177326 26 Q7Z4H7,P61981,P53350,O94927,P07437,Q14203,Q7Z460,Q9H6D7,P41208,P06493,P30153,Q13561,P61163 13 +Signaling by wnt 0.3392222302643631 0.9796926590607176 0.3272378508235769 1.0 0.5475326096399384 82 P49721,Q9UL46,Q99436,P31751,P20618,Q15291,P28070,P05771,P28074,Q92530 10 +Cargo recognition for clathrin mediated endocytosis 0.4025000733179166 0.9788025573435396 0.3276775458883623 1.0 0.5475980504026787 30 P04114,P20645,P11717,Q99627,Q9BT78,Q14108,Q96D71,Q8NC96,P02786 9 +Signaling by pdgf 0.5367236192110225 0.9735323701603752 0.3302887801709477 1.0 0.5497278821894943 6 O00459,P46108 2 +Downstream signal transduction 0.5367236192110225 0.9735323701603752 0.3302887801709477 1.0 0.5497278821894943 6 O00459,P46108 2 +Interferon alpha beta signaling 0.5296912257268364 0.965163282385757 0.3344630345816546 1.0 0.554867679943109 7 P61221,P04439,P10321 3 +Trans golgi network vesicle budding 0.3934529962159165 0.960480025064208 0.3368136794179293 1.0 0.558090060320375 33 P50570,Q9BXS5,P20645,Q9H3P7,P11717,O75976,O60749,Q8NC96,P02786 9 +Dna damage bypass 0.4197547921031369 0.9575949565137314 0.3382670433546235 1.0 0.559819671023935 21 P41440 1 +Homology directed repair 0.3621722591223282 0.9462527234717618 0.3440197003944001 1.0 0.5672797713379312 44 P41440,Q9UNS1,P49005,Q9UQ84 4 +Ire1alpha activates chaperones 0.4034372172107204 0.9246207790618955 0.3551632005589491 1.0 0.5800574613668859 25 P49748,Q9NWM8,O14773,O14653,O43731 5 +Signaling by insulin receptor 0.4561586198655488 0.9150733805203588 0.3601531084513623 1.0 0.586147410384524 15 O00459,P31751,Q9Y487,Q93050,Q9Y5K8 5 +Nef mediated downregulation of mhc class i complex cell surface expression 0.4948490953835951 0.913252727307589 0.3611096385002865 1.0 0.5869641805349486 5 P04439 1 +Carnitine metabolism 0.5224590411229042 0.9071499291730508 0.3643275177638678 1.0 0.5910517028072187 6 P23786,O43772 2 +Separation of sister chromatids 0.3223886852345215 0.9068443945657604 0.3644890895877728 1.0 0.5910517028072187 102 P49721,Q9UL46,Q6P1K2,Q9BUF5,O00231,Q53HL2,Q16763,P60900,Q99436,P28070,P28074,Q92530,P28072,P20618,Q96EE3,Q9UJX3,Q96IY1,P53350,Q6IPU0,Q96FF9,Q71F23,Q9BVA1,Q9UQE7,P57740 24 +Abortive elongation of hiv 1 transcript in the absence of tat 0.44775581096445 0.903426026251032 0.3662998321582364 1.0 0.593284206825011 16 P52298,P35269,Q8IXH7 3 +Unfolded protein response upr 0.3612106561404835 0.8838380894632248 0.3767836216522124 1.0 0.6066704485260006 41 P49748,O43731,Q9Y3B2,P35611,Q5RKV6,Q9NWM8,Q14203,O95070,Q96B26,O94979,P43307,Q9NQT5,Q13868,O14773,Q8N6T3,O14653 16 +Antigen presentation folding assembly and peptide loading of class i mhc 0.4492410232577086 0.8750877362079782 0.3815261693896064 1.0 0.6114258775563797 15 Q03518,P51572,Q9NZ08,P04439,P10321 5 +Rhob gtpase cycle 0.4288483443552014 0.8712220002889839 0.3836329496883244 1.0 0.6133640259929116 18 O00459,P41440,P27105,P02786,Q96RT1 5 +Regulation of tp53 activity through acetylation 0.4533207430068038 0.86442305344303 0.3873555332288125 1.0 0.6178704946601946 14 Q8TBX8,P31751 2 +Synthesis of pips at the plasma membrane 0.5026324554985927 0.8615943765570256 0.3889107665996292 1.0 0.6189068893384088 8 Q13614,Q8TBX8 2 +Telomere c strand lagging strand synthesis 0.4121404288782916 0.8557664036884813 0.3921270018620864 1.0 0.6216317555558821 20 P41440 1 +Nuclear signaling by erbb4 0.4551634833279276 0.8551971866286758 0.3924419934489584 1.0 0.6216317555558821 4 P16949,Q92542,P61201 3 +Transport to the golgi and subsequent modification 0.3289587400664785 0.8439473348735248 0.3986988356574306 1.0 0.6279047331148706 71 Q9UJW0,Q96PC5,Q16706,Q14203,O75396,O15027,Q9BUF5,Q92734,O14653,O60476,P24390,Q12955,Q13190,Q8N6T3,O94979,Q9UP83,Q9Y2V7,Q13561,P83436,Q92538,Q9BVA1,O43731 22 +Signaling by pdgfr in disease 0.5082705400372225 0.8415424587774205 0.4000441093481832 1.0 0.6279498624924899 6 O00459,P62993,Q6UN15,O43815 4 +Gap filling dna repair synthesis and ligation in gg ner 0.4240287445150745 0.8414326840768255 0.4001055817344248 1.0 0.6279498624924899 18 P41440 1 +Sphingolipid de novo biosynthesis 0.4781121192697641 0.8402464980290946 0.4007701924362301 1.0 0.6282716204820259 11 Q9Y5P4,Q96G23 2 +Collagen biosynthesis and modifying enzymes 0.483195257197727 0.8215413809449148 0.4113379633703888 1.0 0.638540508409494 10 Q32P28,O75718 2 +Interleukin 4 and interleukin 13 signaling 0.4652431520285114 0.8212135430071241 0.4115246436786863 1.0 0.638540508409494 12 P09601 1 +Leishmania infection 0.3732583570773212 0.8199583925924793 0.4122398268241032 1.0 0.6389249923679695 34 P07948,Q96F07,P09601,Q9UQB8,P04899 5 +Cilium assembly 0.3346485672057598 0.8111964298727784 0.4172528755293994 1.0 0.6445024642358067 52 Q92973,Q14203,Q7Z460,P36405,Q9BUF5,P61981,P07437,P41208,O75695,Q7Z4H7,O94927,Q13561,P61163,Q9H6D7,P53350,Q15019,Q92538,Q9BVA1,A6NIH7,Q10713,P06493,P30153,P78371 23 +Activation of the pre replicative complex 0.3965852454792118 0.8025267563970242 0.4222483173856126 1.0 0.6507479705367898 21 P25205,Q13416,P33991,Q9Y619 4 +Vesicle mediated transport 0.2856506439410467 0.7970111674191371 0.4254445456171549 1.0 0.6544352544181402 227 Q9UJW0,Q96FZ7,Q96PC5,Q07866,Q6NUQ1,Q16706,Q14203,O75396,O15027,P11717,Q14108,Q9BUF5,Q8NC96,P04114,Q92734,P02786,P40616,O14653,P52732,Q15102,O60476,Q9BXS5,P24390,Q6IQ22,P62993,Q99627,O60749,Q13190,Q5KU26,P50570,Q9UIQ6,O94979,Q12981,Q9UP83,Q9P2W9,O75976,Q8WTV0,Q9Y2V7,Q96D71,Q13561,O00461,P83436,Q14C86,P31751,Q92538,O60664,Q9H3P7,P60520,P20645,Q9BVA1,Q9NRW7,Q9BT78,O60499,P35579,O43731 55 +Transferrin endocytosis and recycling 0.4694959060628113 0.7961311314374951 0.4259558211419585 1.0 0.6544352544181402 11 Q93050,Q9Y487,P02786 3 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.4968073394215961 0.7889456275329194 0.4301437862257442 1.0 0.6584619885448962 6 Q5KU26,P10321 2 +Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.441015183547541 0.783700665889044 0.4332157717196665 1.0 0.6616826368053454 4 O00459 1 +Interleukin 2 family signaling 0.441015183547541 0.783700665889044 0.4332157717196665 1.0 0.6616826368053454 4 O00459 1 +Copi mediated anterograde transport 0.3374029638655619 0.7707333470542936 0.4408650017425606 1.0 0.6718645009833671 48 Q9UJW0,P83436,O43731,P24390,Q12955,Q92538,Q14203,Q9BVA1,Q13561,Q9UP83,Q9BUF5,Q9Y2V7,Q13190,Q8N6T3,O14653 15 +Metalloprotease dubs 0.4381201319558985 0.7691723728932742 0.4417909888116345 1.0 0.6725259261753946 4 Q9NXR7 1 +Deadenylation of mrna 0.4633496743465443 0.7648412238848064 0.4443660968191718 1.0 0.6741936230319733 11 Q14240,P11940,P23588 3 +Inla mediated entry of listeria monocytogenes into host cells 0.3769006793917867 0.7630649616734454 0.4454246549242082 1.0 0.6743028829251303 2 P35222 1 +Intracellular signaling by second messengers 0.3209702809504489 0.7589051424411476 0.4479093025244149 1.0 0.6761503777986358 82 P49721,Q9UL46,Q99436,P31751,Q13555,P20618,P28070,Q8TBX8,O00231,P28074,P84095,Q92530 12 +Rab gefs exchange gtp for gdp on rabs 0.3799194812979429 0.7582288033471939 0.4483140208293077 1.0 0.6761503777986358 25 P31751,Q6IQ22 2 +Mitophagy 0.4515459940411972 0.7493845084046487 0.4536254854204624 1.0 0.6814352072195298 12 Q8N4H5,P21796,Q9NS69 3 +Signaling by interleukins 0.3136629308132195 0.7484773354791356 0.454172290808134 1.0 0.681507707502436 97 P52597,P07948,O00459,P49721,P08670,Q13126,Q99436,Q9UL46,P20700,P09601,P46108,P20618,P28070,O00231,P28074,Q92530 16 +Pcna dependent long patch base excision repair 0.4070711609649726 0.7375289349930438 0.460800753805402 1.0 0.6892873540477319 18 P41440 1 +Activation of ppargc1a pgc 1alpha by phosphorylation 0.3723714008411494 0.7374158071072634 0.4608695256763913 1.0 0.6892873540477319 2 P54619 1 +Signaling by retinoic acid 0.4451952038119015 0.7163852616249727 0.4737534929373412 1.0 0.7047018768719755 12 P50416,Q15118 2 +Vitamin c ascorbate metabolism 0.3970873786407811 0.7130987391500369 0.4757846596655601 1.0 0.7061863515340073 3 P11166,P78417 2 +Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.3957928802589047 0.7062881026818896 0.4800089905970222 1.0 0.7116836118721577 3 P61088,Q15750 2 +Pten regulation 0.3152349548493448 0.7030020330075707 0.4820544825160771 1.0 0.7131693480513824 66 P49721,Q9UL46,Q99436,P31751,P20618,P28070,O00231,P28074,Q92530 9 +Myogenesis 0.4485103626942985 0.691165481688204 0.4894615534627085 1.0 0.7210744167091993 5 P35222,P35221,P19022,O60271 4 +Rhobtb3 atpase cycle 0.3864077669902976 0.6572628470605238 0.5110119212925492 1.0 0.7423520684451805 3 P51151,O60664 2 +Mtor signalling 0.4223294707894381 0.6429355844366927 0.5202658983697954 1.0 0.7518007220629073 13 P31751,P23588 2 +Anti inflammatory response favouring leishmania parasite infection 0.4280307261538912 0.6284101167123254 0.5297353114219727 1.0 0.7605277809259462 12 P07948,O43865,P35579,P63096,P04899 5 +Formation of the early elongation complex 0.3946741430811155 0.6277012150212842 0.530199689262931 1.0 0.7605277809259462 17 P52298,P35269,Q8IXH7 3 +Phosphorylation of the apc c 0.4265057693762834 0.6206925198917497 0.5348019519588356 1.0 0.766325228855061 12 P14635,Q16763,Q9UJX3,P53350 4 +Sema4d induced cell migration and growth cone collapse 0.4070020657204189 0.6159576711456036 0.5379224570934538 1.0 0.7675782868964001 4 P35580 1 +Perk regulates gene expression 0.4074010179117421 0.6108743878191218 0.5412827419198143 1.0 0.768783158432041 14 Q9NQT5,Q9Y3B2,Q5RKV6,Q96B26,P05198,Q13868 6 +Phospholipid metabolism 0.3173646767148445 0.6104273244851246 0.5415787721799967 1.0 0.768783158432041 50 Q13614,Q8IY17,Q8NCC3,Q9NPH0,Q8TBX8 5 +Dual incision in gg ner 0.3666608283989417 0.6072674157735604 0.5436734588135228 1.0 0.7698180485419359 21 P41440 1 +Class i peroxisomal membrane protein import 0.4237476153926254 0.6067795132261269 0.5439972457143454 1.0 0.7698180485419359 12 Q9NR77,Q9Y3D6,O96011 3 +Gap junction trafficking and regulation 0.4478782979830109 0.6046210964551603 0.5454307859460954 1.0 0.7710484843726084 8 Q9BUF5,P50570 2 +Regulation of mecp2 expression and activity 0.4305398913751557 0.6012224922966437 0.547691805409737 1.0 0.7734449359453622 11 Q9BZK7 1 +Cyclin d associated events in g1 0.4372801636790244 0.597707895643853 0.550034856176342 1.0 0.7759521655243131 10 P07948,P30154,P42771,P63151 4 +Cell cycle mitotic 0.2711049887139696 0.5953462998932283 0.5516120130271347 1.0 0.7765742758064811 241 P49721,Q9UL46,Q6P1K2,Q9BRT9,Q9BUF5,O00231,Q53HL2,Q16763,P20700,Q99436,P41440,P07437,Q13416,P28070,P25205,P28074,Q92530,Q9NRF9,Q86XL3,P28072,O94927,P20618,P63151,Q99567,Q96EE3,Q9UJX3,P49005,P14635,Q13561,P05771,Q9H6D7,P33991,P07948,Q96IY1,O15504,P31751,Q6IPU0,Q9Y619,Q9BRX5,Q96FF9,Q9BSJ2,P31350,P57740 43 +Selective autophagy 0.3537431083704227 0.5899345443090009 0.5552345335774782 1.0 0.779266537372087 27 Q15388,Q8N4H5,P08670,Q9NS69,O60664,P21796,Q9BUF5 7 +Rhog gtpase cycle 0.3410187739394083 0.5851703249520281 0.5584331961985032 1.0 0.7811360630168102 35 Q6IAA8,Q86XL3,Q13576,O15173,Q13190,P02786,Q96RT1,P84095 8 +Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.4391780842453342 0.584711158622443 0.5587419497294426 1.0 0.7811360630168102 9 P14635,Q86X55 2 +Ros and rns production in phagocytes 0.4359130326819841 0.56969229445061 0.5688864172588848 1.0 0.7854088458741532 9 Q93050,Q9Y487 2 +Nonhomologous end joining nhej 0.3893808064356781 0.5668522240711538 0.5708145857284417 1.0 0.7854088458741532 16 P12956 1 +Fgfr2 alternative splicing 0.3839840833333408 0.5664293171973794 0.5711019698602109 1.0 0.7854088458741532 17 P52597,P35269,P31943,P52298,P19388 5 +G1 s specific transcription 0.4303385467129036 0.5650159769641171 0.5720628970832202 1.0 0.7859382966983097 10 Q9Y619,P31350 2 +Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.3641298066517622 0.551528152459756 0.5812716733425805 1.0 0.795393771230538 20 P41440 1 +Sealing of the nuclear envelope ne by escrt iii 0.4389201406536087 0.5472625086096811 0.5841983971246802 1.0 0.7971605359108624 7 Q9BVA1,Q9BUF5 2 +Dex h box helicases activate type i ifn and inflammatory cytokines production 0.3377547719184713 0.5470967598167128 0.584312258217033 1.0 0.7971605359108624 2 Q9H2U1 1 +G alpha 12 13 signalling events 0.3911340652224908 0.5405515431073711 0.5888167251035967 1.0 0.8015781165995105 4 Q92974 1 +Signaling by vegf 0.3484480625518753 0.5385671352063477 0.5901855696316827 1.0 0.8015781165995105 24 Q96F07,P31751,P46108,Q9UQB8,P05771 5 +Atf4 activates genes in response to endoplasmic reticulum stress 0.4099484107968639 0.5381390383614603 0.5904810629017907 1.0 0.8015781165995105 12 Q9Y3B2,Q5RKV6,Q96B26,Q9NQT5,Q13868 5 +Hiv infection 0.2781705639410567 0.5325319734588917 0.5943576030956215 1.0 0.8052445805948579 132 P49721,Q9UL46,Q9HBM6,P12956,P35269,O00231,Q8IXH7,P60900,Q99436,P28070,Q96PU5,P28074,Q92530,P28072,P20618,Q92804,Q99567,Q96EE3,O15504,P57740,P52298,P04439,P18615 23 +Extracellular matrix organization 0.3436875671375516 0.5275548969781129 0.5978083046179767 1.0 0.8083125147505185 28 Q08722,Q32P28,O75718,P55081,P13674 5 +Rhod gtpase cycle 0.3443782456600883 0.5257393866484088 0.59906929388278 1.0 0.8086097808889335 27 O00459,P20700,Q5JTV8,P12814,O15173,P50402,Q9UEY8,Q9Y6M7,Q9BX68 9 +Depolymerisation of the nuclear lamina 0.4142807142828557 0.5230142602883665 0.6009643296146263 1.0 0.809377574958812 11 P20700,P50402,P06493,P14635,P05771 5 +Mrna decay by 5 to 3 exoribonuclease 0.4240190347523843 0.5157220249703406 0.6060485694285966 1.0 0.8154216480402476 9 Q9UK45,P62310,Q9Y4Y9 3 +Apoptotic cleavage of cellular proteins 0.383914154888364 0.5106732606072261 0.6095798673535511 1.0 0.8166383198199585 15 Q16625,P51572,P08670 3 +Regulation of plk1 activity at g2 m transition 0.3377524183805608 0.5019712238978673 0.6156877629683648 1.0 0.8196738324645271 30 Q7Z4H7,P61981,P53350,O94927,P07437,P61163,Q14203,Q7Z460,Q13561,P41208,P06493,P30153,P14635,Q9H6D7 14 +Ion homeostasis 0.4023163662205234 0.5009528366497752 0.6164043158548163 1.0 0.8196738324645271 12 Q13555 1 +Cardiac conduction 0.4023163662205234 0.5009528366497752 0.6164043158548163 1.0 0.8196738324645271 12 Q13555 1 +Apc c cdc20 mediated degradation of cyclin b 0.4088931122903189 0.4976406661102014 0.618737335486657 1.0 0.821178580204136 11 P14635,Q16763 2 +Lysosome vesicle biogenesis 0.3856165169200113 0.496311845349875 0.6196744102546281 1.0 0.8214731327644298 14 P20645,P50570 2 +Parasite infection 0.3419890029115273 0.4921097502482364 0.6226417598718446 1.0 0.823163719288986 22 P07948,Q96F07,P46108,P62993,Q9UQB8,P35579 6 +Trafficking of ampa receptors 0.4127533225027057 0.4840696298857558 0.6283364539413061 1.0 0.8272574563765496 10 Q13555 1 +Muscle contraction 0.3388075103537763 0.4831769205443741 0.6289701211619567 1.0 0.8272574563765496 26 P08670,Q13586,P67936,Q13555,O43865,P28289,P23634,P14649 8 +Constitutive signaling by aberrant pi3k in cancer 0.4254559178592331 0.4761962560127751 0.6339345665652234 1.0 0.8300656633090617 6 O00459,P84095,O43815 3 +Rac1 gtpase cycle 0.3154945267675812 0.4718180822368767 0.6370566430524705 1.0 0.8325587294959149 40 O00459,Q9Y4F1,Q6IAA8,Q15758,Q13576,Q96F07,Q9UQB8,P02786,Q96RT1 9 +Mitotic metaphase and anaphase 0.2744811484462634 0.4697538045238353 0.6385309222583533 1.0 0.8336884152121957 134 P49721,Q9UL46,Q6P1K2,P50402,Q9BUF5,O00231,Q53HL2,Q16763,P60900,P20700,Q99436,P28070,P28074,Q92530,Q86XL3,P28072,P20618,P63151,Q96EE3,Q9UJX3,P14635,Q96IY1,P53350,Q6IPU0,Q96FF9,Q71F23,Q8N1F7,Q9BVA1,Q9UQE7,P57740,P06493,O60566 32 +Processing of dna double strand break ends 0.3350369389651629 0.4630962020093899 0.6432954122414833 1.0 0.8355819581846432 27 Q9UNS1,Q9UQ84 2 +Condensation of prophase chromosomes 0.4156048987122275 0.4620610838277826 0.6440375166875321 1.0 0.8355819581846432 8 P14635,Q9NTJ3,P53350 3 +Collagen formation 0.3940683326870769 0.4614762466576524 0.6444569593990561 1.0 0.8355819581846432 12 Q32P28,O75718 2 +Activation of ampk downstream of nmdars 0.3971610537175101 0.4596468986611057 0.6457696903645576 1.0 0.8359537563715437 5 Q9BVA1,Q9BUF5 2 +Cargo concentration in the er 0.3679628191826966 0.4509267722218229 0.6520423272506155 1.0 0.8392350675569049 16 Q13190,Q96PC5,O14653 3 +Er to golgi anterograde transport 0.2922655486083772 0.4499191321341438 0.652768751728833 1.0 0.8392350675569049 67 Q9UJW0,Q96PC5,Q14203,O75396,O15027,Q9BUF5,Q92734,O14653,P24390,Q12955,Q13190,Q8N6T3,O94979,Q9UP83,Q9Y2V7,Q13561,P83436,Q92538,Q9BVA1,O43731 20 +Cell death signalling via nrage nrif and nade 0.4188876739566455 0.4492991333733385 0.6532158828679933 1.0 0.8392350675569049 6 Q92974,Q14344 2 +Insulin receptor recycling 0.4046108131769439 0.4476331479536101 0.6544179761122366 1.0 0.8399900219205891 10 Q93050,Q9Y487 2 +Ksrp khsrp binds and destabilizes mrna 0.389348698516768 0.4392496917523633 0.6604806225601942 1.0 0.8429028559725268 12 Q96B26,Q5RKV6,Q9Y3B2,Q9NQT5 4 +Beta catenin phosphorylation cascade 0.3915155440414487 0.4356706605526143 0.6630756955987556 1.0 0.8429028559725268 5 P35222,P30154,Q14738,P30153 4 +Signaling by ctnnb1 phospho site mutants 0.3915155440414487 0.4356706605526143 0.6630756955987556 1.0 0.8429028559725268 5 P35222,P30154,Q14738,P30153 4 +Disassembly of the destruction complex and recruitment of axin to the membrane 0.3915155440414487 0.4356706605526143 0.6630756955987556 1.0 0.8429028559725268 5 P35222,P30154,Q14738,P30153 4 +Signaling by fgfr2 0.3446069633224283 0.4351273564399047 0.6634699875833496 1.0 0.8429028559725268 20 P52597,P35269,P31943,P62993,P52298,P19388,Q01085 7 +Signaling by fgfr 0.3446069633224283 0.4351273564399047 0.6634699875833496 1.0 0.8429028559725268 20 P52597,P35269,P31943,P62993,P52298,P19388,Q01085 7 +Rac2 gtpase cycle 0.3216746063403908 0.4170697382478161 0.6766273988965961 1.0 0.8572285952656598 33 O00459,Q6IAA8,Q86XL3,O15173,Q13505,P02786,Q96RT1 7 +Nr1h2 and nr1h3 mediated signaling 0.4068915684555018 0.4123117091003565 0.6801109674194525 1.0 0.8584595498267698 7 Q9BZK7 1 +Wnt ligand biogenesis and trafficking 0.3827720207253868 0.3992760163359141 0.6896898370831757 1.0 0.8672254710324323 5 Q96QK1,Q9Y3A6,O75436,O60493 4 +Dag and ip3 signaling 0.4058386738466825 0.3971842581133075 0.6912315897120564 1.0 0.8672254710324323 6 P13861,Q13555,O43865 3 +Beta oxidation of pristanoyl coa 0.3591993155090743 0.3968249712055943 0.6914965350587792 1.0 0.8672254710324323 4 O15254 1 +Membrane trafficking 0.2661024110566237 0.3933638101578218 0.6940507950065262 1.0 0.869631014458223 220 Q9UJW0,Q96FZ7,Q96PC5,Q07866,Q6NUQ1,Q16706,Q14203,O75396,O15027,P11717,Q14108,Q9BUF5,Q8NC96,P04114,Q92734,P02786,P40616,O14653,P52732,Q15102,O60476,Q9BXS5,P24390,Q6IQ22,P62993,Q99627,O60749,Q13190,P50570,Q9UIQ6,O94979,Q12981,Q9UP83,Q9P2W9,O75976,Q9Y2V7,Q96D71,Q13561,O00461,P83436,Q14C86,P31751,Q92538,O60664,Q9H3P7,P60520,P20645,Q9BVA1,Q9NRW7,Q9BT78,O60499,P35579,O43731 53 +Signaling by egfr 0.3801142201818323 0.3884017980857326 0.6977187137931544 1.0 0.871033316671454 5 P62993,P42566 2 +Butyrate response factor 1 brf1 binds and destabilizes mrna 0.3901160227172875 0.3846845342177443 0.7004711549912046 1.0 0.8722925961940281 10 Q96B26,Q5RKV6,Q9Y3B2,Q9NQT5 4 +Robo receptors bind akap5 0.3057263021675802 0.3844543169354096 0.7006417488083707 1.0 0.8722925961940281 2 P13861 1 +Regulation of lipid metabolism by pparalpha 0.3236333539750716 0.3826118647395133 0.7020075717168464 1.0 0.8725472441041293 25 O75448,Q71SY5,P50416,Q9BZK7,P23786,Q86X55 6 +Resolution of abasic sites ap sites 0.3230474977565757 0.3771516006897091 0.7060609459096887 1.0 0.8735725278638786 24 P41440 1 +Miro gtpase cycle 0.3518938167691717 0.3658205843442627 0.7144989588935382 1.0 0.8807214398624588 4 Q8IWA4,O95140,Q8IXI1 3 +Oncogenic mapk signaling 0.3210573250420139 0.3640156051740878 0.7158463564195086 1.0 0.8807938516880901 22 Q99956,Q13555,Q6WCQ1 3 +Mitochondrial biogenesis 0.3094085955437791 0.3631007358836209 0.7165296349278387 1.0 0.8808417364625499 36 P48735,P00846,Q13505,Q9NX63,Q5XKP0,Q9BZK7,Q96RR1 7 +Dual incision in tc ner 0.3149424532788898 0.3616260859767705 0.7176314683703224 1.0 0.8814036094000276 32 P41440 1 +Rhoj gtpase cycle 0.3311608750324957 0.3587662061965389 0.7197699954424777 1.0 0.8819982844244646 20 O00459,Q15758,P27105,P02786,Q9Y6M7 5 +Cell cycle 0.2409836899658224 0.3585420050412131 0.7199377389254611 1.0 0.8819982844244646 289 P49721,Q9UL46,Q6P1K2,Q9UQ84,Q9BRT9,Q9BUF5,O00231,Q53HL2,Q16763,P20700,Q99436,P41440,P07437,Q13416,P28070,P25205,P28074,Q8WXH0,Q92530,Q9NRF9,Q86XL3,P28072,O94927,O94901,P20618,P63151,Q99567,Q96EE3,Q9UJX3,P49005,P14635,Q13561,P05771,Q9H6D7,P33991,Q9NXR7,P07948,Q96IY1,O15504,P31751,Q6IPU0,Q9Y619,Q9BRX5,Q96FF9,Q9BSJ2,P31350,Q9UQE7,P57740 48 +Clathrin mediated endocytosis 0.291848593241775 0.3576580413497051 0.7205992368159082 1.0 0.8819982844244646 48 P04114,P50570,Q14C86,P20645,P11717,Q99627,Q14108,Q8NC96,P02786 9 +Transcriptional activation of mitochondrial biogenesis 0.3561099243110094 0.3506744716557428 0.7258325794717284 1.0 0.8859045858373685 14 Q9BZK7,P48735,Q96RR1 3 +Rho gtpases activate ktn1 0.3884869293471074 0.3398180341964448 0.7339935659407462 1.0 0.8942684533342246 7 Q07866,P84095,P63000 3 +Signaling by ptk6 0.3665310364993474 0.336084446683777 0.7368071867088544 1.0 0.8968970830195939 12 O75525,P23246,P46108,P63000,P40763,Q07666 6 +Signaling by fgfr2 in disease 0.3631783536979941 0.3215967041368445 0.747758241020529 1.0 0.9057063579751432 12 P52298,P35269 2 +Pyruvate metabolism 0.3380194093169237 0.3203778428772572 0.7486819199063 1.0 0.9057063579751432 17 O95563,P21796,Q15118 3 +Rho gtpases activate wasps and waves 0.3410983932226168 0.3152488861548504 0.7525726906210521 1.0 0.9092057624299106 16 Q9UQB8 1 +Methylation 0.3830352154422282 0.3109635111848611 0.7558283611924672 1.0 0.9111264283510606 6 Q9NZL9,P21964 2 +Synthesis of substrates in n glycan biosythesis 0.3745303449837411 0.307450579331622 0.7585004344139454 1.0 0.9127377586653728 9 Q86YN1,Q9NR45 2 +Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.3653338632218947 0.3054921738530163 0.759991329637995 1.0 0.91277494749093 11 Q96B26,Q5RKV6,Q9Y3B2,Q9NQT5 4 +Translation of replicase and assembly of the replication transcription complex 0.3370022661055236 0.3052282382207659 0.760192326937605 1.0 0.91277494749093 4 Q99570,Q96FZ7,O43633 3 +Organelle biogenesis and maintenance 0.2804099489348904 0.289593154750683 0.7721275044274623 1.0 0.9226449665722344 88 Q92973,Q14203,Q7Z460,P36405,Q9BZK7,Q9BUF5,Q9NVH1,Q00059,Q15648,Q16891,P07437,Q13505,Q5XKP0,O75964,O75695,Q7Z4H7,P00846,O94927,P06576,Q9NX63,Q96RR1,Q13561,Q9H6D7,P61163,P48735,P53350,Q15019,Q92538,Q9BVA1,A6NIH7,P54619,Q10713,P06493,P30153,P78371,O75431,Q86X55 37 +Biological oxidations 0.2895781697849368 0.2878221184448275 0.7734829054073011 1.0 0.9226449665722344 41 P07099,P30837,Q5VT66,Q16850 4 +Mtorc1 mediated signalling 0.3697244854350203 0.2789388802466989 0.7802917301164831 1.0 0.9283366362656504 8 P23588 1 +Activation of nmda receptors and postsynaptic events 0.3320710232943646 0.2727267532581272 0.7850632678926979 1.0 0.930773189253528 16 Q13555,P63000,Q9BVA1,P54619,Q9BUF5,P51812,P07196,P13861 8 +Miscellaneous transport and binding events 0.37179931802596 0.2710861757678858 0.7863247537636358 1.0 0.9314609518153292 6 Q8TDW0,Q9UEY8 2 +Intrinsic pathway for apoptosis 0.3179246608914376 0.2637948321859614 0.7919380168899899 1.0 0.9348698351369744 19 Q13794 1 +Recycling of eif2 gdp 0.3468264248704644 0.2608181753199632 0.7942327275610992 1.0 0.9359621884276056 5 Q14232,P05198,P20042,Q9NR50 4 +Signaling by fgfr2 iiia tm 0.3531059657906202 0.2567202518649793 0.7973947366479959 1.0 0.936459282644167 11 P52298 1 +Fgfr2 mutant receptor activation 0.3531059657906202 0.2567202518649793 0.7973947366479959 1.0 0.936459282644167 11 P52298 1 +G protein mediated events 0.3579996991645583 0.2557857968565362 0.7981162416332739 1.0 0.9365020620709744 10 O43865,Q13555,P63096,P04899,P13861 5 +Activation of atr in response to replication stress 0.3095146207694376 0.2442254793913739 0.8070561947301491 1.0 0.9421427740253978 20 P25205,Q9Y619,P33991 3 +Signaling by scf kit 0.3563593760271909 0.2396275470820145 0.8106190073817945 1.0 0.9434418969122828 9 P07948,O00459 2 +Processing of intronless pre mrnas 0.3129174086571586 0.2392236882991975 0.8109321352391605 1.0 0.9434418969122828 19 O95639,Q86U42,P51003,P52298,O94913,Q92797,Q5KU26 7 +Deactivation of the beta catenin transactivating complex 0.35318624077299 0.2379341487042447 0.8119321691231001 1.0 0.943802104754488 10 P31751 1 +Extension of telomeres 0.2968369011387521 0.2314056403070194 0.8169996837394673 1.0 0.9446555567312748 29 P41440 1 +Fcgamma receptor fcgr dependent phagocytosis 0.296725926096617 0.230756889025419 0.8175036749181404 1.0 0.9446555567312748 29 O00459,P07948,Q96F07,P46108,P62993,Q9UQB8,P35579,Q8IZP0 8 +Golgi cisternae pericentriolar stack reorganization 0.352964400012302 0.2275838185824981 0.8199698007679523 1.0 0.946704998015026 9 P14635,P53350 2 +Heparan sulfate heparin hs gag metabolism 0.3318062101758784 0.2092706923220442 0.8342369293708012 1.0 0.95621343474073 5 Q7LGA3,P54802 2 +Egfr downregulation 0.3109478696942195 0.2089326380560164 0.8345008249054067 1.0 0.95621343474073 4 P62993 1 +Response to elevated platelet cytosolic ca2 0.289239646204431 0.2031184982557944 0.8390424135772405 1.0 0.9606122105193364 33 Q9UHQ9,Q92520,O43852,Q8NBX0,Q8NBM8,Q06481,O94919,P05771 8 +Tp53 regulates metabolic genes 0.2869077675572422 0.2015736196922573 0.8402500703079374 1.0 0.9611898293815484 35 Q6IAA8,O43819,P31751,P00403,Q9NQ88,P13073,P09669 7 +Respiratory electron transport 0.2624508117035365 0.1991612848824473 0.8421365829013014 1.0 0.9617382696959724 57 Q9P0J0,O95182,O43819,P51970,Q8N183,P00403,O75380,P21912,O43678,Q9Y375,P03886,P13073,O43676,O96000,P09669 15 +Assembly of the orc complex at the origin of replication 0.3457331155131388 0.1957641719764429 0.8447947540448153 1.0 0.9620827355706107 8 Q9Y619 1 +Signaling by alk in cancer 0.2899369433719854 0.1944701576561769 0.8458077603899186 1.0 0.9620827355706107 30 P67936,Q07866,O94979,P62993,Q8WWI1,P35579,Q92734,O43815 8 +Rna polymerase ii transcription 0.2371125813217309 0.1921689981160325 0.8476098292095462 1.0 0.9620827355706107 316 P49721,Q9UL46,Q9HBM6,Q86U42,Q9UQ84,Q15291,Q9BZK7,Q9HCL2,O00231,Q03164,P09669,Q16763,Q8IXH7,Q8WXI9,Q99436,Q16625,Q13555,P28070,Q96PU5,Q16629,P13073,P28074,Q5KU26,Q92530,Q9Y3Y2,Q96J02,P20618,Q92804,Q13794,Q9UJX3,Q8TBX8,P14635,P05771,Q9BXW9,Q71SY5,O43819,Q9H814,P31751,P52298,Q86X55 40 +Hur elavl1 binds and stabilizes mrna 0.3059242473292295 0.191962529207786 0.8477715568765107 1.0 0.9620827355706107 4 O14980,Q15717,P35658 3 +Ca2 pathway 0.3059242473292245 0.1919625292077693 0.8477715568765238 1.0 0.9620827355706107 4 P35222,P63218,Q9HCE1 3 +Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.3059242473292237 0.1919625292077664 0.8477715568765261 1.0 0.9620827355706107 4 P30153,P30154,Q14738 3 +Tp53 regulates transcription of cell cycle genes 0.3231911102066064 0.1838797044467738 0.8541078268231461 1.0 0.964930082039042 13 P14635,Q86X55 2 +Cristae formation 0.2921814861651274 0.1813399486067827 0.8561007513344636 1.0 0.9652882500583876 21 Q5XKP0,Q13505,P00846 3 +Rab regulation of trafficking 0.2866052285044256 0.1786427723167059 0.8582182072249973 1.0 0.9652882500583876 31 Q14C86,P31751,Q6IQ22 3 +Rnd1 gtpase cycle 0.3099458864608358 0.1764810905036208 0.8599160031156918 1.0 0.9653841534591286 16 O00459,P02786,O75976,P38159 4 +Opioid signalling 0.3094271951411034 0.1743736616515948 0.8615718121581104 1.0 0.9653841534591286 16 O43865,Q13555,P30154,P30153,P63096,P04899,P13861 7 +Signaling by rho gtpases miro gtpases and rhobtb3 0.2513557928324541 0.1703247126623382 0.8647547773162949 1.0 0.9669099166230566 233 Q9Y4F1,Q13576,Q07866,Q9Y266,Q6P1K2,P30519,P30154,P50402,P62995,Q9BUF5,P02786,Q53HL2,Q8IZP0,P84095,Q13526,O00459,Q96CS3,Q14126,Q15904,P20700,Q14344,P41440,P67936,O15173,Q13505,P62993,Q9UQB8,Q13190,P80723,P07910,Q9Y6M7,Q92974,P38159,Q96HY6,Q9BX68,Q9NYL9,Q6IAA8,P08670,Q86XL3,P12814,Q96F07,P42167,Q03001,O75976,Q96EE3,P27105,Q9P0I2,P05771,Q99707,Q9BZD4,P35580,Q96IY1,Q15758,Q5JTV8,P53350,O60664,Q6IPU0,Q71F23,Q7Z6E9,P51572,Q9BVA1,Q9UEY8,Q9BT78,P57740,P62070,P35579,Q07065,P78371,O60566,Q96RT1 70 +Signaling by fgfr in disease 0.2938431685463759 0.1691601961833604 0.8656706373784271 1.0 0.9669099166230566 20 P52298,P35269,O95429 3 +Fanconi anemia pathway 0.3183290155440392 0.1666922045330815 0.8676122395991364 1.0 0.9669099166230566 5 Q9NVI1,P27694,Q9BXW9,Q16658 4 +Platelet homeostasis 0.3278885930818389 0.1651778914347069 0.8688039663066012 1.0 0.9669099166230566 11 P23634 1 +G2 m dna damage checkpoint 0.2834572870363845 0.1643175910810835 0.8694811342315418 1.0 0.9669099166230566 32 P14635,Q9UQ84 2 +Rhoc gtpase cycle 0.2844914464076974 0.1600054218968689 0.8728768031917142 1.0 0.9675339254550858 27 P41440,Q96RT1,P02786,P27105 4 +Formation of tubulin folding intermediates by cct tric 0.3305222186182325 0.1598525376300656 0.8729972371111585 1.0 0.9675339254550858 10 P50991,Q9BVA1,Q99832,P17987,P40227,P78371,Q9BUF5,P48643,P50990 9 +Complex i biogenesis 0.2818568064098838 0.1593421484248896 0.873399315297422 1.0 0.9675339254550858 33 Q9P0J0,O95182,P51970,Q8N183,O75380,O43678,Q9Y375,P03886,O43676,O96000 10 +Transcriptional regulation by tp53 0.2571352950134792 0.1583671487210772 0.8741674985972141 1.0 0.9676007858966734 118 Q9BXW9,Q8WXI9,Q9HBM6,O43819,P31751,Q9UQ84,Q92804,Q13794,P13073,Q8TBX8,P14635,Q86X55,P09669,Q8IXH7 14 +Base excision repair 0.2831850090779274 0.1536960607980901 0.8778493909047551 1.0 0.9693215810717288 28 P41440 1 +Folding of actin by cct tric 0.3303079416531709 0.1478796361302752 0.8824377595085999 1.0 0.9735737755955692 8 P50991,Q99832,P17987,P40227,P78371,P48643,P50990 7 +Bbsome mediated cargo targeting to cilium 0.3300939423388421 0.14114693213943 0.8877538682604416 1.0 0.976765109006231 6 P50990,P50991,P17987,P78371,P48643 5 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.3259893367304347 0.1397244784084874 0.8888776851527076 1.0 0.976765109006231 9 Q16763 1 +Rho gtpases activate nadph oxidases 0.3280997730296823 0.1357250401158231 0.8920386517412806 1.0 0.979451274642836 6 P05771,Q13526,P63000 3 +Mitochondrial calcium ion transport 0.298847653423635 0.1330058291028611 0.8941887705044269 1.0 0.9810241165967508 16 Q96TA2,P21796,P45880,Q10713,Q9UJZ1 5 +Syndecan interactions 0.3060233160621742 0.1310775945110706 0.8957139252132673 1.0 0.98155542550849 5 P05556,O14936,P06756,P12814 4 +Mitotic prometaphase 0.2655784728814223 0.1213193267151821 0.9034381125792328 1.0 0.9872101517952128 87 Q9Y266,Q6P1K2,Q14203,Q7Z460,P30154,Q9BUF5,Q53HL2,P61981,P07437,P41208,Q9BW27,Q7Z4H7,Q9NQS7,Q9Y6G9,O94927,P07900,Q96EE3,P14635,Q9NTJ3,P67870,Q9H6D7,Q9BZD4,P61163,Q13561,Q8N0S6,Q29RF7,Q8TD19,Q96IY1,P53350,Q6IPU0,Q96FF9,Q71F23,Q9BSJ2,Q9BVA1,Q9UQE7,P57740,P06493,P30153,O60566 39 +Regulation of tp53 activity 0.2568358889998937 0.1195058651699222 0.9048745936047072 1.0 0.9879900714517852 54 Q92804,P31751,Q8TBX8,Q9UQ84 4 +Initiation of nuclear envelope ne reformation 0.2912097158135345 0.1150254019747984 0.9084249878092674 1.0 0.9908738144393336 17 Q86XL3,P20700,P63151,P50402,P06493,P14635 6 +Rhoq gtpase cycle 0.2879741525803238 0.114343570135594 0.9089654449940924 1.0 0.9908738144393336 18 P02786,Q15758,Q9Y6M7,P27105 4 +Visual phototransduction 0.3184529980424566 0.1105961409163051 0.9119366078162154 1.0 0.9918781070862172 6 P04114 1 +Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.3142714215934526 0.1104772669646006 0.912030877831512 1.0 0.9918781070862172 10 Q16763 1 +Copi dependent golgi to er retrograde traffic 0.2622248382472651 0.1092828322388324 0.912978162923701 1.0 0.9918781070862172 42 P24390,Q07866,Q6NUQ1,Q92538,O75396,Q12981,Q9BVA1,Q9P2W9,Q9BUF5,P52732,O43731 11 +Signaling by receptor tyrosine kinases 0.260781285783056 0.1090988867786073 0.9131240578421485 1.0 0.9918781070862172 106 P52597,Q96J02,P07948,P50570,P31751,Q96F07,P46108,P35269,Q9Y5K8,Q9Y487,P05771,P52298,Q9UQB8,Q93050,Q96P70,Q96RT1 16 +Suppression of phagosomal maturation 0.3142209264658246 0.1001561285464982 0.9202203751655242 1.0 0.994419962728278 6 Q14974,P52294,P20339,P51149,Q9H267 5 +Fcgr3a mediated il10 synthesis 0.3119969545424059 0.0948145651457039 0.9244621176799004 1.0 0.9966401536817222 6 P07948,O43865 2 +Amino acids regulate mtorc1 0.302544524165521 0.0872054096199161 0.9305082394857296 1.0 1.0 11 Q9Y5K8,Q96EE3 2 +Neurotransmitter receptors and postsynaptic signal transmission 0.2694065812808583 0.0850530626849416 0.9322192055785536 1.0 1.0 28 P51812,Q13555,P63000,Q9BVA1,P05771,P54619,Q9BUF5,P63096,P04899,P07196,P13861 11 +Trna modification in the mitochondrion 0.3074421201029417 0.084188136714155 0.9329068502329648 1.0 1.0 6 O75648 1 +Dna replication initiation 0.3059967585089262 0.0822840499618239 0.9344208376929112 1.0 1.0 8 P09884,Q9NRF9,P49643,P49642,Q9NR33,Q07864,Q14181 7 +Non integrin membrane ecm interactions 0.30612244897959 0.0811883855654458 0.935292135999731 1.0 1.0 6 P12814,P07942,P06756,P05556,O14936 5 +Late endosomal microautophagy 0.304612205364855 0.0808927645845977 0.9355272341341028 1.0 1.0 9 O60664,P08670 2 +Fgfr1 mutant receptor activation 0.3043548148863007 0.0802461696400171 0.9360414704700424 1.0 1.0 9 P40763,Q16630,O95429,P62993 4 +Signaling by fgfr1 in disease 0.3043548148863007 0.0802461696400171 0.9360414704700424 1.0 1.0 9 P40763,Q16630,O95429,P62993 4 +Potential therapeutics for sars 0.2658559440879862 0.0751176853566254 0.940121076699406 1.0 1.0 34 Q99720,Q8WXI9 2 +Fceri mediated mapk activation 0.2835011857926675 0.0744614671603423 0.9406432007680724 1.0 1.0 5 P07948 1 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.2547206925383232 0.0740056463801111 0.9410058924218728 1.0 1.0 68 Q9P0J0,O95182,P00846,P51970,O43819,Q8N183,P00403,O75380,P21912,O43678,O75964,Q9Y375,P03886,P13073,O43676,O96000,P09669 17 +Signaling by braf and raf1 fusions 0.2739494336855638 0.0732166782530471 0.9416336946812972 1.0 1.0 19 Q6WCQ1,Q13555 2 +Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.2781735751295315 0.0627385181357987 0.9499747247573644 1.0 1.0 5 Q99808,P12235,P36404,P05141 4 +Rab geranylgeranylation 0.2598692518292608 0.0582010592900212 0.9535884769630668 1.0 1.0 22 Q6IQ22 1 +Processing of capped intronless pre mrna 0.2605929633830958 0.0476371703959993 0.9620054079518552 1.0 1.0 21 Q86U42,P51003,P52298,Q5KU26 4 +Recycling pathway of l1 0.2687932890348271 0.0391859997327399 0.9687420956587562 1.0 1.0 17 P50570,Q9BVA1,P35241,Q9BUF5,P15311 5 +Copi independent golgi to er retrograde traffic 0.252916433026724 0.0320587847302153 0.9744251715225024 1.0 1.0 22 Q9UJW0,Q15102,Q9Y6G9,Q14203,Q9BVA1,Q9BUF5,Q13561 7 +Signaling by notch1 0.2787594290773986 0.0281735716988182 0.977523715583827 1.0 1.0 11 Q9BZK7 1 +Signaling by csf3 g csf 0.2801527558004792 0.0277150114434585 0.977889450902367 1.0 1.0 7 P07948 1 +Cdc42 gtpase cycle 0.2560404695808757 0.0262065755964668 0.9790925711175 1.0 1.0 28 O00459,Q9Y4F1,Q6IAA8,P27105,Q9UQB8,P02786 6 +Cooperation of prefoldin and tric cct in actin and tubulin folding 0.2665544761579562 0.0208584524134482 0.983358569577644 1.0 1.0 14 Q9BVA1,Q9UHV9,O60925,Q9BUF5 4 +Rhoh gtpase cycle 0.2571847738973477 0.0175158506491074 0.9860250877969476 1.0 1.0 19 Q15758,P02786,P27105,Q9Y6M7 4 +Nuclear events kinase and transcription factor activation 0.2747587582768085 0.0158015692001328 0.9873926965530088 1.0 1.0 10 P30154,P51812,P50570 3 +Rhobtb1 gtpase cycle 0.2576421657168545 0.0126267924415936 0.9899255449640478 1.0 1.0 18 P08670,Q7Z6E9,Q9BT78,P62995,P07910,P38159 6 +M phase 0.2476236058586414 0.0009989911357406 0.9992029205289924 1.0 1.0 184 Q96FZ7,P49721,Q9UL46,Q6P1K2,P50402,Q9BUF5,O00231,Q53HL2,Q16763,P60900,P20700,Q99436,P07437,P28070,P28074,Q92530,Q86XL3,P28072,O94927,P20618,P63151,Q99567,Q96EE3,Q9UJX3,P14635,Q9NTJ3,P05771,Q9H6D7,Q13561,Q96IY1,O15504,P53350,Q6IPU0,Q96FF9,Q71F23,Q9BSJ2,Q8N1F7,Q9BVA1,Q9UQE7,P57740,P06493,O60566 42 +Signaling by flt3 fusion proteins 0.2425518134715001 0.0007275695454411 0.9994194835439988 1.0 1.0 5 Q9UBW7,P62993,Q14789,Q01082 4 +Flt3 signaling in disease 0.2425518134715001 0.0007275695454411 0.9994194835439988 1.0 1.0 5 Q9UBW7,P62993,Q14789,Q01082 4 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9fa096f008208a4d43a185b194e42c1544bcfa2c --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of gene expression by srebf srebp", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pe", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha defensins", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd22 mediated bcr regulation", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate biosynthesis", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Chylomicron remodeling", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of particulate exogenous antigens phagosomes", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Dectin 2 family", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Defensins", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of base excision repair", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Elevation of cytosolic ca2 levels", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythrocytes take up carbon dioxide and release oxygen", "Erythropoietin activates phosphoinositide 3 kinase pi3k", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Erythropoietin activates stat5", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Ncam1 interactions", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O glycosylation of tsr domain containing proteins", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr regulates axonogenesis", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Phase 0 rapid depolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 24 hydroxycholesterol", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldl clearance", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc transporters"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APBB1", "APEH", "APEX1", "APLP2", "APOB", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8A", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3B", "ATG3", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATRIP", "ATRX", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BARD1", "BASP1", "BAX", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCKDHA", "BCKDHB", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BRCA1", "BRD1", "BRD2", "BRD4", "BSG", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "CAB39", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC22", "CCDC59", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA5", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2A", "CENPC", "CENPI", "CENPL", "CENPP", "CENPQ", "CENPU", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHST14", "CHTOP", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLNS1A", "CLSPN", "CLTB", "CLTC", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT9", "COA1", "COG2", "COG5", "COG6", "COG7", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ9", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC3", "DNAJC7", "DNAJC8", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPM1", "DPYSL2", "DPYSL5", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHD1", "EHHADH", "EHMT1", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERLEC1", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESCO2", "ESD", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF2", "FAHD1", "FAM114A2", "FAM3C", "FAM49B", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FIP1L1", "FIS1", "FKBP14", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FOXK1", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "FYTTD1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GINS3", "GINS4", "GLA", "GLB1", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLS", "GLUD1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPI", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILK", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INCENP", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "ISCU", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIN9", "LIPA", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMO7", "LNPEP", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPPRC", "LRRC1", "LRRC8A", "LRRC8C", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LYN", "LYPLA1", "M6PR", "MAGED2", "MAGT1", "MAIP1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAPK1", "MAPRE1", "MARC1", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MFAP1", "MFN1", "MFN2", "MGAT1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYDGF", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1C", "MYO6", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAPA", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCOR1", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NLN", "NME1", "NMT1", "NNT", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN4", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCK2", "PCMT1", "PCNA", "PCYOX1L", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELP1", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "POFUT1", "POFUT2", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPID", "PPIE", "PPIH", "PPIL3", "PPIL4", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUS1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QTRT2", "RAB10", "RAB11B", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBBP7", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "REPS1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIPK1", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPS1", "RP2", "RPA1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP36", "RRP7A", "RRP8", "RRP9", "RSF1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SC5D", "SCAMP1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35B2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLIT2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX9", "SOAT1", "SOD2", "SORD", "SPAG9", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPOP", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX10", "STX18", "STX3", "STX5", "STX6", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SYMPK", "SYNE2", "SYS1", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL3", "TCEA1", "TCP1", "TDRKH", "TECR", "TERF2", "TERF2IP", "TEX10", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TLE3", "TLN1", "TM7SF2", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM126B", "TMEM59", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMX3", "TNPO1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRMT1", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSG101", "TSN", "TSNAX", "TST", "TTC26", "TTC37", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAP1", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBIAD1", "UBN1", "UBR4", "UBTF", "UCHL5", "UFD1", "UFL1", "UGGT1", "UHRF1", "UMPS", "UNC119B", "UPF1", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USO1", "USP10", "USP14", "USP19", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WBP11", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WFS1", "WIPI2", "WTAP", "XAB2", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZMYM2", "ZNF512B", "ZNF638", "ZW10", "ZWILCH"], "leading_proteins": ["ABCB1", "ABCE1", "ABI1", "ACADVL", "ACAT2", "ACBD3", "ACOX3", "ACP6", "ACTN1", "ACTR1A", "ADD1", "ADD3", "AHCYL1", "AKT2", "ALDH1B1", "ANAPC7", "ANK3", "ANKLE2", "ANO6", "AP1M1", "APLP2", "APOB", "ARFGAP1", "ARHGEF2", "ARL1", "ARL2", "ARL3", "ASNA1", "ATP13A1", "ATP2B4", "ATP5B", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "B4GAT1", "BABAM2", "BAG4", "BAG6", "BAIAP2", "BASP1", "BCAP31", "BLVRA", "BNIP1", "BUB1B", "C19orf70", "CALU", "CAMK2G", "CARM1", "CASK", "CCNB1", "CCT2", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD47", "CDCA5", "CDCA8", "CDH2", "CDK1", "CDK4", "CDKAL1", "CDKN2A", "CENPL", "CENPP", "CENPU", "CERS2", "CETN2", "CHCHD3", "CHMP2A", "CHMP6", "CHTOP", "CKAP4", "CLASP1", "CLCN3", "COG2", "COG5", "COG6", "COG7", "COL4A3BP", "COLEC12", "COMT", "COPS2", "COPS4", "COPS8", "COX2", "COX4I1", "COX6C", "CPD", "CPSF4", "CPSF6", "CPT1A", "CPT2", "CRK", "CRTAP", "CSK", "CSNK2B", "CTNNA1", "CTNNB1", "CYB5R1", "CYFIP2", "CYP51A1", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCUN1D5", "DDRGK1", "DHCR24", "DHPS", "DHRS4", "DHX36", "DNAJC11", "DNM2", "DOLPP1", "DSG2", "DST", "DUSP9", "DYNC1LI1", "ECE1", "ECH1", "EIF2B1", "EIF2B3", "EIF2S1", "EIF2S2", "EIF4A2", "EIF4B", "ELAVL1", "EMC3", "EMD", "ENDOD1", "EPHA7", "EPHX1", "EPS15", "ERAP1", "ERBIN", "EXO1", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC6", "EXOSC8", "EZR", "FADS2", "FAF2", "FAM114A2", "FAM3C", "FANCD2", "FANCI", "FARP1", "FECH", "FIP1L1", "FIS1", "FKBP14", "FSCN1", "GABARAPL2", "GALNT7", "GAPVD1", "GATAD2B", "GBF1", "GGCX", "GINS3", "GINS4", "GLG1", "GNA13", "GNAI1", "GNAI2", "GNG5", "GOLGA5", "GOLGB1", "GOLIM4", "GOSR2", "GPAM", "GRB2", "GSTO1", "GTF2F1", "HAUS4", "HAUS5", "HAUS6", "HINT2", "HLA-A", "HLA-C", "HMOX1", "HMOX2", "HNRNPC", "HNRNPF", "HNRNPH1", "HS2ST1", "HSD17B12", "HSP90AA1", "ICMT", "IDH1", "IDH2", "IGF2BP1", "IGF2R", "IMMT", "INCENP", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGAV", "ITGB1", "KDELR1", "KDELR3", "KDM1B", "KHDRBS1", "KHDRBS3", "KIF11", "KLC1", "KMT2A", "KPNA1", "KPNB1", "LAMB1", "LAMTOR1", "LMNB1", "LMO7", "LNPEP", "LRRC8C", "LSM3", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LYN", "M6PR", "MAN1A2", "MAN2A1", "MARC1", "MAT2B", "MAVS", "MCM3", "MCM4", "MED1", "MED24", "MED25", "MFAP1", "MFN1", "MFN2", "MIA2", "MOV10", "MPC2", "MPRIP", "MRC2", "MSMO1", "MTAP", "MTMR2", "MTR", "MTX1", "MTX2", "MYH10", "MYH9", "MYL6B", "NAGLU", "NANS", "NCBP2", "NCEH1", "NCSTN", "ND1", "NDUFA13", "NDUFA2", "NDUFA7", "NDUFA8", "NDUFAF1", "NDUFAF2", "NDUFB10", "NDUFB3", "NDUFS6", "NECAP1", "NEDD4L", "NEFL", "NEK9", "NELFCD", "NELFE", "NPC1", "NPEPPS", "NSL1", "NSUN2", "NT5C3B", "NUB1", "NUDC", "NUF2", "NUP107", "NUP214", "NUP85", "NUP88", "NUP93", "NUPL2", "OCLN", "ORC2", 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0.2993998188698849 1.0 1.0 1.0 0.0294507732567689 0.1506847481690166 +Transcriptional activation by nrf2 in response to phytochemicals 0 5 1.9874755718131236 0.0468697203391361 0.8762135922330098 4.242718446601942 0.717175969663976 0.3989152917542212 1.1327932797172364 1.1057310494588604 0.9463878468242582 0.2968222225345399 1.0 1.0 0.1180585699575878 0.2731207001200411 0.4744622644152227 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..87d171a32a0557837c87b0c5333ee72913decdf6 --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 591, + "title": "Average number of proteins per term", + "value": 9.830795262267344 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3e6b92ebb6acb6c16d019e7778eec44f97678024 --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3bea4712346c2d6aff144d8d114e324029ecb146 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,168 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Pkcgamma calcium signaling pathway in ataxia 0.9414428987382728 3.7343262521073135 0.0001882183762083 0.1052827479184446 0.0042169311623268 2 Q15118 1 +Irinotecan pathway 0.8456810093820841 3.2964796549514763 0.0009790470539186 0.4394855411259851 0.0106667747651101 2 O15118 1 +Congenital generalized lipodystrophy cgl 0.8188288579747752 3.1691193698519147 0.0015290158378613 0.5951909933074655 0.0150608060029343 2 P31751 1 +Pi3kaktmtor signaling pathway and therapeutic opportunities 0.8619799764091118 3.0974664377948664 0.0019518249631986 0.6848339900122697 0.0180238836445378 3 Q15118 1 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.8933842026332549 2.9786894959794616 0.0028948396735952 0.8197357330612836 0.02444071781564 4 P09601 1 +Serotonin and anxiety 0.7670656745389945 2.917502792878312 0.0035284648883491 0.8761904053057457 0.0285645377812415 2 P05771 1 +Prostaglandin and leukotriene metabolism in senescence 0.7538013587835726 2.8516842200131705 0.0043488278910459 0.9239041938236487 0.0334385315703307 2 P09960 1 +Nocgmppkg mediated neuroprotection 0.7767268973367014 2.701421033549659 0.0069043873645504 0.9833383359086576 0.0423049837245637 3 Q13555 1 +Cancer immunotherapy by pd1 blockade 0.6949207376253712 2.552605692969185 0.0106920463803008 0.9982585264763504 0.0554039355318474 2 P04439 1 +Methylation pathways 0.7345832596400856 2.4979994437654773 0.0124896389795263 0.9994055413763104 0.0605030871877056 3 Q9NZL9 1 +Signal transduction through il1r 0.6823034616628922 2.487012368793699 0.0128820920158483 0.999530000700017 0.0613977127529545 2 Q9BQ95 1 +Mitochondrial complex iv assembly 0.7630880502378158 2.2891917488444964 0.0220682138020571 0.999998127764805 0.0869487623801051 11 P14406,P09669,Q7KZN9,O43819 4 +Metabolic pathway of ldl hdl and tg including diseases 0.7229877314196758 2.2043657237726517 0.0274986341914651 0.9999999303181004 0.1015730800447243 4 Q8WTV0 1 +Purinergic signaling 0.6647707767742668 2.14937809702565 0.0316044402581554 0.9999999942826 0.1125194228468064 3 P04899 1 +Kisspeptinkisspeptin receptor system in the ovary 0.7378069153341962 2.0838979795363124 0.0371694481817073 0.999999999810343 0.1269777102623642 5 P31751,Q15118 2 +Il10 antiinflammatory signaling pathway 0.6871625299268267 2.031911043210519 0.0421626623676316 0.9999999999912212 0.1376986258331224 4 P09601 1 +Vitamin a and carotenoid metabolism 0.6288487247650996 1.9643013489845331 0.0494951553530622 0.9999999999999064 0.150781633060102 3 Q8WTV0 1 +Dna mismatch repair 0.5885199667881834 1.9278742914686604 0.0538707641750706 0.999999999999994 0.1624368450380956 19 P41440,Q9UQ84 2 +Ketogenesis and ketolysis 0.7316742464330646 1.9171333918982176 0.0552209874136648 0.9999999999999972 0.1648262806135148 7 P23786 1 +Oxidation by cytochrome p450 0.7384142714776654 1.906361524765544 0.0566033169564734 0.9999999999999988 0.1672628016063791 6 Q9UHQ9,Q16850 2 +1q211 copy number variation syndrome 0.6871517213947144 1.846311200499193 0.0648470323756866 1.0 0.1868637590955549 10 Q9NPH0 1 +Striated muscle contraction pathway 0.7124777836327294 1.789586112792939 0.0735204726464093 1.0 0.2069076158763235 6 P67936,P08670,P28289 3 +Hostpathogen interaction of human coronaviruses apoptosis 0.5522484632805009 1.7792062873419223 0.0752059479685063 1.0 0.2106479395705556 2 Q07812 1 +Translation factors 0.4947146496574162 1.7525531285060656 0.0796787427687339 1.0 0.2180662541664289 33 P23588,O75822,O75153,P55010,P11940,O15372 6 +Proteasome degradation 0.4693290169627617 1.749145876387339 0.0802658069029689 1.0 0.218453575108742 39 P49721,Q9UL46,P28072,Q99436,P04439,P20618,P28070,O00231,P28074,P10321 10 +Dna repair pathways full network 0.4371225881819127 1.716584197824709 0.0860551717894033 1.0 0.231175484216079 48 P41440,P12956,Q9UQ84 3 +Methionine metabolism leading to sulfur amino acids and related disorders 0.6137568367572239 1.6683880680802117 0.0952387153584553 1.0 0.2479563029817051 4 P55263 1 +Interactions between loxl4 and oxidative stress pathway 0.5721682847896402 1.664794898873617 0.0959536820072672 1.0 0.2487220441504165 3 Q9BQ95,Q8TAG9 2 +Dna damage response 0.5131434771800596 1.6608489992166868 0.0967437773557642 1.0 0.2496749887216447 22 P41440,P14635,Q13794 3 +Acquired partial lipodystrophy barraquersimons syndrome 0.6086772000612891 1.642766320831064 0.1004312909486275 1.0 0.2569475885309043 4 P20700,O60725 2 +Mirna regulation of dna damage response 0.4990477555004928 1.5776185684399533 0.1146532639596142 1.0 0.2849746377890499 23 P41440,P14635,Q13794 3 +Type i collagen synthesis in the context of osteogenesis imperfecta 0.5984338856119897 1.4663581016496972 0.142550754419708 1.0 0.3397076446050299 11 Q32P28,Q96AY3,O75718 3 +Familial partial lipodystrophy fpld 0.6270741617461573 1.4297651071226891 0.1527844467901689 1.0 0.3589346356100568 7 P31751,Q03252,P20700,O60725 4 +Nucleotidebinding oligomerization domain nod pathway 0.6293774170731892 1.4073529242196778 0.1593227630759035 1.0 0.3692539332465058 6 Q96RT1 1 +Apoptosis modulation and signaling 0.5603726690733732 1.399002760950886 0.1618121551285121 1.0 0.3717146444058239 13 O95831,O95817,Q13794 3 +Leptininsulin signaling overlap 0.4755742478162417 1.3375076531737815 0.1810569858235644 1.0 0.4004820944820579 2 P40763 1 +Phosphoinositides metabolism 0.6087218585774665 1.310877623947991 0.1898991117349133 1.0 0.4126116729240213 6 Q8TBX8 1 +Statin inhibition of cholesterol production 0.5998681395906094 1.3002844952717862 0.1935034800931747 1.0 0.4186367809534714 7 Q8WTV0 1 +Hepatitis c and hepatocellular carcinoma 0.5995105114626407 1.298577990703611 0.1940887952305434 1.0 0.4186367809534714 7 P31350,P63000,P40763,P62993,P38398 5 +Nanomaterial induced apoptosis 0.5710273001592583 1.2870634734841078 0.1980721654101263 1.0 0.4226016236728687 5 O95831 1 +Chemokine signaling pathway 0.4943123028680038 1.2804579056976328 0.2003841400200237 1.0 0.4259964991073166 18 P07948,O00459,P31751,P46108,P04899,P05771 6 +Mitochondrial long chain fatty acid betaoxidation 0.5180897622625222 1.2762345273387092 0.2018726267118713 1.0 0.4276226608842866 15 P49748,P23786,O43772 3 +Modulators of tcr signaling and t cell activation 0.5757457546956113 1.25164441823149 0.2106994615885931 1.0 0.4415326317691648 9 O00459,P62993,O96000,Q12824 4 +Hostpathogen interaction of human coronaviruses autophagy 0.4957928802589045 1.249649426537247 0.2114276392397185 1.0 0.4415326317691648 3 Q99570,P42345 2 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.4501317196719079 1.247158999462056 0.2123392031827253 1.0 0.4418748911302489 24 Q9BWD1,P48449,Q15392,Q16850,Q15800 5 +Synaptic signaling pathways associated with autism spectrum disorder 0.5729629219316179 1.2031753040468072 0.2289084894661646 1.0 0.4648966229364374 8 Q05086,P31751 2 +Thermogenesis 0.4374690981741131 1.194795492658276 0.2321669418109406 1.0 0.4698995294872121 27 P23786 1 +G1 to s cell cycle control 0.4376036091315989 1.1581821762215867 0.246789700393653 1.0 0.494118920683105 24 P49642,Q9Y619,Q13416,P42771,P06493,P25205,P14635,P33991 8 +Erbb signaling pathway 0.5153763245018901 1.1501308513259518 0.2500899812615671 1.0 0.4959838218979401 13 O00459,P31751,P46108,Q13555,P05771 5 +Mecp2 and associated rett syndrome 0.4452067891006428 1.1296157028429088 0.2586381913581759 1.0 0.5067467919599098 21 P52597,Q03518,P67809,Q9UQE7,Q05086 5 +Nsp1 from sarscov2 inhibits translation initiation in the host cell 0.5115425941433283 1.1288840424697202 0.2589467532519336 1.0 0.5067467919599098 13 P55010,O75822 2 +Alzheimers disease and mirna effects 0.3525540589513604 1.1137791368633476 0.2653739494480682 1.0 0.5169903120908379 72 O00459,P49721,P17655,P28072,Q99436,Q13564,Q07866,P07437,P31751,P21796,P20618,P28070,P45880,Q9BUF5,Q96IX5,P28074 16 +Dna replication 0.4222940539979357 1.1124825731487142 0.2659307189096696 1.0 0.5169903120908379 29 P41440,Q9Y619,P25205,P49005,P33991 5 +Metapathway biotransformation phase i and ii 0.431188178066378 1.0945257698588216 0.2737244515306354 1.0 0.5269418594612558 22 P07099,Q86UY6,Q16850 3 +Camkk2 pathway 0.5382452312347583 1.0650131666206035 0.2868699715201428 1.0 0.5451451870366701 9 O00429,Q9Y3D6,P09601 3 +Pparalpha pathway 0.5429089387901075 1.0566340093808233 0.2906786528173333 1.0 0.5486762649500948 8 P23786 1 +Copper homeostasis 0.552845871839978 1.0489040123770432 0.2942222986623966 1.0 0.5502701851565708 6 P35670,Q8N668,O43819 3 +Intracellular trafficking proteins involved in cmt neuropathy 0.515007981932908 1.0314336899965766 0.3023374889315549 1.0 0.5587045495837256 11 Q13614,Q9UI14,Q9NR77 3 +Caloric restriction and aging 0.4559870550161866 1.0310583415433108 0.3025134617035399 1.0 0.5587045495837256 3 P43490,P42345 2 +Mammary gland development pathway involution stage 4 of 4 0.4559870550161866 1.0310583415433103 0.3025134617035401 1.0 0.5587045495837256 3 P40763,Q07812 2 +Methionine de novo and salvage pathway 0.5240535329801702 0.9945463311867688 0.3199569610303769 1.0 0.5836251974350395 9 Q13126 1 +Folate metabolism 0.4691914421834326 0.9907495868330424 0.3218078713889782 1.0 0.5851952368950344 15 P41440,Q8WTV0 2 +Ranklrank signaling pathway 0.5220328461771917 0.984531928498217 0.3248540406982085 1.0 0.5878879308627902 9 P07948,P31751 2 +Alzheimers disease 0.3410163650083571 0.9815981678958076 0.3262978504384284 1.0 0.5879330171009488 71 O00459,P49721,P17655,P28072,Q99436,Q13564,Q07866,P07437,P31751,P21796,P20618,P28070,P45880,Q9BUF5,P28074 15 +Embryonic stem cell pluripotency pathways 0.5214832189974773 0.9525381322936024 0.3408241366027147 1.0 0.6017036902732896 8 O00459,P31751 2 +P53 transcriptional gene network 0.5091954141179117 0.952058655143749 0.3410672356033029 1.0 0.6017036902732896 10 P11166,Q9NQ88,Q709F0,Q13794 4 +Influence of laminopathies on wnt signaling 0.5260501989443874 0.9478687973180684 0.3431962514666242 1.0 0.6036576923118301 7 O75844,P50402,O60725 3 +Translation inhibitors in chronically activated pdgfra cells 0.4548856376759109 0.9456935754164508 0.3443049002955045 1.0 0.6038106708446385 16 O00459,P31751,Q15118,P23588 4 +Complement system in neuronal development and plasticity 0.517681944057553 0.934138965800497 0.3502322142958944 1.0 0.6123882800262533 8 Q5KU26 1 +B cell receptor signaling pathway 0.4832876305376413 0.9168982913754754 0.3591959394053046 1.0 0.6262088501136726 12 P07948,P05771,P46108,O00459 4 +Micrornas in cardiomyocyte hypertrophy 0.4826831679864646 0.9136778070524476 0.3608861687554077 1.0 0.6273050756895469 12 P31751,P05771 2 +Sulfation biotransformation reaction 0.4326860841423998 0.9038633327217792 0.3660678742215448 1.0 0.6287853240504038 3 P11413,O43252 2 +Male infertility 0.4267560526705459 0.9025068623652048 0.3667876777171586 1.0 0.6287853240504038 19 P04114,P08183,P41440,Q15165 4 +Fatty acid betaoxidation 0.4003965099272661 0.8810922026494976 0.3782679172261727 1.0 0.6405625761623728 22 P49748,P23786,O43772 3 +Regulation of actin cytoskeleton 0.3889649409227576 0.8765611322011684 0.3807250583038248 1.0 0.6428814555930299 30 O00459,Q96F07,P46108,P35241,Q9UQB8,Q8TBX8 6 +Nucleotide excision repair 0.4040186679069865 0.8520212805649217 0.3942022809305394 1.0 0.6619183381335915 21 P41440 1 +Regulation of wnt bcatenin signaling by small molecule compounds 0.3911355548366241 0.8444605613057848 0.3984120928629615 1.0 0.6651456126610459 2 P35222 1 +3q29 copy number variation syndrome 0.5062770097876426 0.8323664006202894 0.4052021611770222 1.0 0.6726811158865735 6 P52298 1 +Allograft rejection 0.4930502721062654 0.8157156924587249 0.4146627617278104 1.0 0.6830044473032296 8 P10321,P08670,P08183 3 +Chromosomal and microsatellite instability in colorectal cancer 0.4324571169958792 0.8133048131590638 0.4160433181542515 1.0 0.6830044473032296 16 Q13794 1 +Splicing factor nova regulated synaptic proteins 0.4345663482015257 0.7908454496243055 0.4290341842667178 1.0 0.6946827476756993 15 Q13573,Q9UBB6,Q12955,Q13555,Q06481 5 +Nonsmall cell lung cancer 0.4490383190720877 0.7853503885706228 0.4322481599588272 1.0 0.6979744878023686 13 O00459,Q15118,P31751,P62993,P05771 5 +Vitamin dsensitive calcium signaling in depression 0.4882166259897275 0.7699734342396211 0.4413156513768554 1.0 0.7087433422927216 7 P23634 1 +S1p receptor signal transduction 0.4874134095437497 0.7662448493535435 0.4435306269102308 1.0 0.7103701910676055 7 P31751 1 +Mitochondrial complex i assembly model oxphos system 0.3714524927343272 0.7585675138503227 0.4481113120161559 1.0 0.7138376965001297 31 Q9P0J0,O95182,P51970,Q8N183,O75380,Q96CU9,O43678,Q9Y375,P03886,O43676,O96000 11 +Kit receptor signaling pathway 0.4432542298401604 0.7541632596874008 0.450751195896268 1.0 0.7141929136050789 13 P07948,P05771,P46108,O00459 4 +Tcell receptor tcr signaling pathway 0.4644429199750463 0.7033955497013243 0.4818092791664559 1.0 0.7473734487857622 9 O00459,P46108,P08670 3 +Electron transport chain oxphos system in mitochondria 0.3176808731047371 0.7008093278516595 0.4834220160350966 1.0 0.7479120719286442 55 Q7KZN9,O95182,P00846,P51970,P00403,O75380,O43678,O75964,P03886,P13073,P14406,O43676,O96000,P09669 14 +Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.4156685011330439 0.6580053149097812 0.5105347159378888 1.0 0.7738541578457495 4 P06753,P18031,P61201 3 +Cholesterol biosynthesis with skeletal dysplasias 0.4672657199487114 0.6557661827226194 0.5119745782025178 1.0 0.7738541578457495 6 Q16850 1 +Angiopoietinlike protein 8 regulatory pathway 0.3596022086268864 0.612768946267494 0.5400291267910284 1.0 0.8058086375722114 24 P41440,P31751,P46108 3 +Ethanol effects on histone modifications 0.4306110085906035 0.6015694527641307 0.5474607677022276 1.0 0.810900535619089 11 P41440,Q9H9T3,O14929,Q96KQ7 4 +Progeriaassociated lipodystrophy 0.4423070782763898 0.5991799442706509 0.5490528954048544 1.0 0.8112256529606723 9 Q03252,P20700,O60725 3 +Mammary gland development pathway embryonic development stage 1 of 4 0.3432546101585182 0.576513773487659 0.5642679627950702 1.0 0.8268700868229625 2 O60315 1 +Folatealcohol and cancer pathway hypotheses 0.3422840504690978 0.5712961533461653 0.5677989087801052 1.0 0.8285658150346721 2 Q99707 1 +Nongenomic actions of 125 dihydroxyvitamin d3 0.4420185958449395 0.5608045461902924 0.5749307871827267 1.0 0.8286859425507144 7 Q13555 1 +Il18 signaling pathway 0.3073051970579725 0.5603092594062616 0.5752685127302923 1.0 0.8286859425507144 53 Q13011,P50416,P09601,Q9HC07,Q9NQX7,Q9UMR5,P05771,Q9Y6M7 8 +Calcium regulation in cardiac cells 0.3519336152590063 0.5581840387710137 0.5767187189054712 1.0 0.8286859425507144 23 P05771,Q13555,P23634 3 +Hijack of ubiquitination by sarscov2 0.3928716200916461 0.5486975833369226 0.5832130049355397 1.0 0.8286859425507144 4 Q13617,Q13564 2 +Head and neck squamous cell carcinoma 0.4023831633764879 0.5399745649267607 0.5892145734940983 1.0 0.8286859425507144 13 P31751 1 +Type i interferon induction and signaling during sarscov2 infection 0.3622337552388109 0.534455889858806 0.5930261597852844 1.0 0.8286859425507144 3 Q7Z434 1 +Eicosanoid metabolism via lipooxygenases lox 0.4379397587897669 0.5284127644307924 0.5972128800170811 1.0 0.8286859425507144 6 O15254,P09960 2 +Nitric oxide metabolism in cystic fibrosis 0.3884309293185447 0.5279375849466302 0.5975426570364035 1.0 0.8286859425507144 4 Q86X55 1 +Disruption of postsynaptic signaling by cnv 0.43274556178461 0.5065213913192936 0.6124906766712472 1.0 0.8406429884450445 6 Q06787,Q7L576,Q13555 3 +Cholesterol biosynthesis pathway 0.4033004473969507 0.5057135620050737 0.61305774622642 1.0 0.8406429884450445 12 Q15800,P48449,Q16850 3 +Tolllike receptor signaling pathway 0.4273244720607162 0.4972845320153023 0.6189884179578462 1.0 0.8430042349899121 7 P31751 1 +15q112 copy number variation syndrome 0.3752337293459336 0.467466105375009 0.6401664367133182 1.0 0.8606592948260288 4 Q06787,Q9BSJ2 2 +G protein signaling pathways 0.3878348062928292 0.4673794102071416 0.6402284509993366 1.0 0.8606592948260288 13 Q92667,Q14344,P05771,O43823,P63096,P04899 6 +Epithelial to mesenchymal transition in colorectal cancer 0.3552317693037867 0.4646001156600696 0.6422178494387119 1.0 0.8606592948260288 19 Q16625 1 +Met in type 1 papillary renal cell carcinoma 0.3671484361196683 0.4466390280118004 0.6551357116281893 1.0 0.8666770158115423 16 O00459,P31751,P46108,Q92733,O43815 5 +Dna damage response only atm dependent 0.3387316566400191 0.4342864967564896 0.6640804082693015 1.0 0.8738437482065785 21 P31751,Q13794 2 +Epo receptor signaling 0.3908151565148175 0.4327214969000393 0.665217110669339 1.0 0.8738437482065785 5 Q15118 1 +Pathogenic escherichia coli infection 0.3487856817137905 0.4279787700579302 0.6686665769521849 1.0 0.8738789939255242 19 Q16625,P07437,Q9BUF5 3 +Pdgfrbeta pathway 0.4111368880652953 0.4181217467380467 0.6758581058505975 1.0 0.8778728363905562 6 P62993,P05771,P19525 3 +Ciliopathies 0.36330454067537 0.3849682072897728 0.7002609705583582 1.0 0.8977315262472662 14 Q8TD19,P36405,Q13432,Q10713,O75695,Q9UBB4,Q9NVR5 7 +Egfr tyrosine kinase inhibitor resistance 0.3676846819730596 0.3712864781915898 0.7104241681842809 1.0 0.9087893580019696 13 O00459,P31751,P05771 3 +Selenium micronutrient network 0.3731101581918885 0.3650422830080976 0.7150798436188956 1.0 0.9120164328807124 12 Q8WTV0 1 +Pathways of nucleic acid metabolism and innate immune sensing 0.3730629518677967 0.360005582346918 0.7188429589707812 1.0 0.9120164328807124 5 Q9Y3Z3 1 +16p112 proximal deletion syndrome 0.3196125850933967 0.35551220077835 0.7222059062405641 1.0 0.9120164328807124 22 Q8TF05,Q16204 2 +Nuclear receptors metapathway 0.289156972095949 0.3434341021061898 0.7312719080763723 1.0 0.9156391899854576 49 P23786,Q9HCL2,P09601,P08183 4 +Sphingolipid pathway 0.3805408986283114 0.3310447829947014 0.7406106588930157 1.0 0.9158153875553462 9 Q9Y5P4,Q96G23 2 +Insulin signaling 0.3064182711739728 0.3307842710634899 0.7408074425808335 1.0 0.9158153875553462 35 P41440,P46108,P31751,P05771 4 +Sphingolipid metabolism integrated pathway 0.3847099263205337 0.3254838153508513 0.7448149298470288 1.0 0.9158153875553462 7 Q96G23 1 +Sphingolipid metabolism overview 0.3847099263205337 0.3254838153508513 0.7448149298470288 1.0 0.9158153875553462 7 Q96G23 1 +Cellular proteostasis 0.3393479076841551 0.3145254236049186 0.7531220102366734 1.0 0.9158169149244418 4 O60925 1 +Pyrimidine metabolism 0.296962180046501 0.3123170865739841 0.754799555848974 1.0 0.9158169149244418 39 Q9H773 1 +Nonalcoholic fatty liver disease 0.2818866523412645 0.3104647818715411 0.7562075371964934 1.0 0.9158169149244418 52 O00459,Q96J02,Q9P0J0,O95182,P51970,P31751,P00403,O75380,P21912,O43678,P13073,P14406,O43676,O95168,O96000,P09669 16 +Vitamin d receptor pathway 0.3502953388339793 0.2934662881635457 0.7691657638364098 1.0 0.9265094881038234 13 P08183 1 +Nad metabolism sirtuins and aging 0.307443365695798 0.2845888973008416 0.7759591183395198 1.0 0.9311899518630248 3 P43490,Q00059 2 +Sterol regulatory elementbinding proteins srebp signaling 0.3030171176077514 0.28314423911525 0.7770662706103377 1.0 0.9311899518630248 32 Q9HCL2,Q16850,Q8WTV0 3 +Il5 signaling pathway 0.3681446257584124 0.2731614978583828 0.7847290750749527 1.0 0.9322648197386924 8 P07948,O00459 2 +Vitamin b12 metabolism 0.3637995612244989 0.2574810382853138 0.796807451240261 1.0 0.9350887151946032 8 Q8WTV0 1 +Initiation of transcription and translation elongation at the hiv1 ltr 0.360506680278819 0.2546178436290041 0.7990182760969113 1.0 0.9350887151946032 9 Q8IXH7 1 +Corticotropinreleasing hormone signaling pathway 0.3334018922656473 0.2486976082324301 0.8035946990803218 1.0 0.9382122749362384 14 P42892,P05771 2 +Small cell lung cancer 0.3470557313676072 0.2335961965676898 0.8152984807671761 1.0 0.9466432261952872 11 P31751 1 +Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.3530551333597295 0.2138062161604178 0.8306981772498756 1.0 0.960266170298124 7 P62993,Q15118 2 +Integrinmediated cell adhesion 0.3114104582098374 0.2131818837773572 0.8311850981411064 1.0 0.960266170298124 18 O00459,P46108,P31751,P17655 4 +Novel intracellular components of rigilike receptor rlr pathway 0.3525807503791014 0.2122580541259982 0.8319057177540432 1.0 0.960266170298124 7 Q13573,Q7Z434,Q13526,Q92841 4 +Joubert syndrome 0.3150668300039673 0.197670185458588 0.843303117966969 1.0 0.9620127405746196 16 Q8TD19,P36404,P36405,Q13432,Q10713,O75695,Q92878 7 +Glioblastoma signaling pathways 0.3204268423647153 0.1953349383376919 0.84513074700532 1.0 0.9620127405746196 14 O00459,P62993,P31751,P05771 4 +Oxidative phosphorylation 0.2853822493765873 0.1920434924046389 0.8477081374161186 1.0 0.9620127405746196 35 O75787,P00846,O95182,P51970,O75380,O43678,P03886,O96000 8 +Hedgehog signaling pathway wp4249 0.3059242473292266 0.1919625292077761 0.8477715568765185 1.0 0.9620127405746196 4 Q13618,P48729,O43791 3 +Proximal tubule transport 0.3327875291165639 0.1819327543808633 0.8556354991618025 1.0 0.9620127405746196 11 P08183 1 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.3277823588994252 0.1814006278188317 0.8560531261252902 1.0 0.9620127405746196 12 O75844,P50402,O60725 3 +Fluoropyrimidine activity 0.3325788138790636 0.1665090603175681 0.8677563536010087 1.0 0.9674249060730862 10 Q99808,P31350,P04818,Q06203 4 +Hepatitis b infection 0.2923911040502756 0.16258384400569 0.8708461083432857 1.0 0.9674249060730862 20 O00459,P31751,Q7Z434,P05771 4 +Type 2 papillary renal cell carcinoma 0.3304773453687956 0.1533283935117773 0.8781393106243995 1.0 0.9694478422134872 9 Q13617,P11166,P23246,Q92733 4 +Myometrial relaxation and contraction pathways 0.3034893519850292 0.1507707765895633 0.8801565396055284 1.0 0.9694478422134872 16 Q13555 1 +Nucleotide excision repair in xeroderma pigmentosum 0.2811070806542988 0.145434974949213 0.884367452190638 1.0 0.9694478422134872 30 P41440 1 +Circadian rhythm genes 0.2710917126855507 0.144994485915082 0.8847152253865438 1.0 0.9694478422134872 40 Q9UNS1,Q8N163,P50416,Q05086,Q03164 5 +Il1 signaling pathway 0.3028572641725754 0.1224393124337008 0.902551105889301 1.0 0.9715987314764606 5 O00459,Q9BQ95,Q15750 3 +Bladder cancer 0.2973078191050881 0.1078285742192763 0.9141316760848066 1.0 0.9787170662429724 5 O00459 1 +Spinal cord injury 0.2901512507933764 0.1014055524383449 0.9192285289886768 1.0 0.9797633760756738 16 O94813,P08670 2 +Primary focal segmental glomerulosclerosis fsgs 0.2898439358811856 0.1003299783952865 0.920082358243653 1.0 0.9797633760756738 16 P08670,P46939,Q14108 3 +Tca cycle in senescence 0.302251325870351 0.0733050383472048 0.9415633824680228 1.0 0.996612941196539 8 Q15118 1 +Nephrotic syndrome 0.299960001120543 0.0719385397929 0.9426508191689768 1.0 0.996612941196539 10 O75844,P35579,Q14108 3 +Melanoma 0.2915097017559696 0.0667113770942414 0.9468114768794648 1.0 0.997644083993465 12 O00459,P62993,P31751 3 +Endometrial cancer 0.293486336990037 0.0630659779949578 0.9497139659744452 1.0 0.998720558524728 11 O00459,P31751 2 +Atm signaling pathway 0.2773608566228665 0.0534823782933413 0.9573475706378674 1.0 1.0 15 P14635,Q9BXW9,P38398 3 +16p112 distal deletion syndrome 0.2910858995137866 0.0483663433037096 0.9614242820513526 1.0 1.0 8 Q99873,Q8NCF5,P20339,P62993,Q9H2V7,P20338,Q8WWM7 7 +Genes related to primary cilium development based on crispr 0.2904692624525446 0.0475954323620055 0.9620386723530008 1.0 1.0 9 Q10713 1 +Eicosanoid metabolism via cyclooxygenases cox 0.2886214654067411 0.0447890064089532 0.96427548791498 1.0 1.0 6 O15254 1 +Fragile x syndrome 0.2570205587757757 0.0283220683421373 0.9774052796666663 1.0 1.0 32 Q96F07,P50570,Q15118 3 +Amyotrophic lateral sclerosis als 0.2807288112483564 0.0276889331680411 0.9779102503734136 1.0 1.0 8 P07197,P20339,P63000,O96008,P07196 5 +Ccl18 signaling pathway 0.2771898796972503 0.0247746216381744 0.9802347338428764 1.0 1.0 11 P07196,P00403,P08670,O60315 4 +Disorders of folate metabolism and transport 0.2770576798444712 0.0222640650444191 0.9822373137126292 1.0 1.0 7 Q99707,P22102,P00374,P34897,P11586,P04818 6 +Egfegfr signaling pathway 0.2539974572591119 0.0167626462927704 0.98662596964764 1.0 1.0 34 O00459,Q96J02,Q9P0J0,P00403,P46108,P63000,P40763,P62993,P42566,P05771,P51812,Q8IZP0,P41240 13 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9c07ee6f451262b2df4362be293664c4b568a2a2 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Ganglio sphingolipid metabolism", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes associated with the development of rheumatoid arthritis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpr143 in melanocytes and retinal pigment epithelium cells", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactions of natural killer cells in pancreatic cancer", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoblast signaling", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAR2", "AARS", "AASS", "ABAT", "ABCB1", "ABCC1", "ABCD3", "ABCF1", "ABCF2", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANXA1", "ANXA2", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APBB1", "APEX1", "APLP2", "APMAP", "APOB", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARL8B", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATIC", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AURKA", "AURKB", "B3GAT3", "BAG2", "BAG3", "BAG4", "BAIAP2", "BAK1", "BANF1", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BCAS3", "BCAT2", "BCKDHA", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BLM", "BLVRA", "BMI1", "BPTF", "BRCA1", "BRD1", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "C1QBP", "CAAP1", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CANT1", "CAP1", "CAPN1", "CAPN2", "CAPZB", "CARM1", "CASK", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR2", "CCDC124", "CCDC6", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC73", "CDCA5", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2A", "CEBPZ", "CECR2", "CELF1", "CELF2", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHMP6", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CIP2A", "CKB", "CLASP1", "CLCN7", "CLIC1", "CLPTM1L", "CLSPN", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT9", "CNP", "COA1", "COA3", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COQ8A", "COQ9", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPT1A", "CPT2", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DARS", "DCAF1", "DCAF7", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DECR1", "DEK", "DERL1", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX36", "DHX38", "DHX8", "DHX9", "DIAPH1", "DLAT", "DLD", "DLST", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC1", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHD1", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMD", "ENAH", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPRS", "EPS15", "ERBIN", "ERCC3", "ESCO2", "ESD", "ESS2", "ETF1", "ETFA", "ETFDH", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOSC2", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAM120A", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIS1", "FKBP10", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FOXRED1", "FSCN1", "FTL", "FTO", "FUCA1", "FUS", "FXR1", "G3BP1", "G6PD", "GABARAPL2", "GAPDH", "GART", "GBA", "GCDH", "GCLC", "GDAP1", "GGCT", "GGCX", "GGH", "GID8", "GIGYF2", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GM2A", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPI", "GPS1", "GPT2", "GRB2", "GRSF1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F2", "GTF2I", "GTPBP4", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOXD11", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP3", "ILF2", "ILK", "IMPAD1", "IMPDH2", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIDINS220", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF4A", "KIF5B", "KLC1", "KMT2A", "KMT2B", "KPNA1", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3BP", "LIG1", "LIG3", "LIN9", "LIPA", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPCAT3", "LPGAT1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM4", "LSM7", "LSS", "LTA4H", "LUC7L", "LYN", "MACF1", "MAEA", "MAGT1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MEPCE", "MFAP1", "MFN2", "MGST1", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MOCS1", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPI", "MPP1", "MPST", "MRE11", "MRI1", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTR", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1C", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAM1", "NCAPG", "NCAPG2", "NCBP1", "NCBP2", "NCDN", "NCKAP1", "NCL", "NCOR1", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NFATC2IP", "NIPBL", "NKRF", "NME1", "NME6", "NONO", "NOP2", "NPC1", "NPC2", "NR2F2", "NSD1", "NSDHL", "NSF", "NT5C3A", "NTHL1", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCLN", "OGDH", "OGT", "OPA1", "ORC2", "ORC3", "ORC6", "OXCT1", "P3H1", "P4HA1", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELO", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGRMC2", "PGS1", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PIAS1", "PIGT", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PKN2", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMAIP1", "PMPCA", "PMVK", "PNP", "PNPLA8", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB21", "RAB2A", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RBBP7", "RBM14", "RBM17", "RBM39", "RBM4", "RBM5", "RBMX", "RBPJ", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RIF1", "RIPK1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPS1", "RP2", "RPA1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP38", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RTCB", "RTF1", "RTN3", "RTN4", "RUVBL1", "S100A10", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARS", "SC5D", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SDHC", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEL1L", "SEPT11", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SFPQ", "SFSWAP", "SGPL1", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIN3A", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMYD3", "SNAP23", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SPEN", "SPNS1", "SPOP", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRPK2", "SRRM1", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSR4", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STIP1", "STMN1", "STOM", "STRAP", "STRN", "STUB1", "STX3", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SUZ12", "SYNE2", "TAB1", "TACO1", "TALDO1", "TAP1", "TARDBP", "TBC1D4", "TBCA", "TBL1XR1", "TBL2", "TCF20", "TCP1", "TECR", "TELO2", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMELESS", "TIMMDC1", "TJP1", "TK1", "TKT", "TLE3", "TLN1", "TM7SF2", "TMED10", "TMEM126B", "TMEM165", "TMEM43", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNPO1", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP3A", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRIP4", "TRRAP", "TSG101", "TSPYL1", "TTC19", "TTC26", "TTF1", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TXNDC15", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBAP2L", "UBE2J1", "UBE2L3", "UBE2N", "UBE3A", "UBIAD1", "UBR5", "UBTF", "UCHL5", "UFD1", "UGGT1", "UHRF1", "UMPS", "UNC119", "UPF1", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP10", "USP5", "USP7", "USP9X", "UTRN", "VANGL1", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS16", "VPS33A", "VPS4A", "WAPL", "WARS", "WDHD1", "WDR1", "WDR26", "WDR5", "WDR74", "WFS1", "WIPI2", "XAB2", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YES1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZEB2", "ZFR", "ZMPSTE24", "ZNF281", "ZNF318", "ZYX"], "leading_proteins": ["ABCB1", "ABI1", "ACAD11", "ACADVL", "ACAT2", "ACOX3", "ACP6", "ADK", "AIFM1", "AKAP1", "AKAP8", "AKT2", "ANK3", "APLP2", "APOB", "ARL2", "ARL3", "ATP2B4", "ATP5L", "ATP6", "ATP6AP2", "ATP7B", "ATXN10", "ATXN2L", "BAG3", "BAIAP2", "BAX", "BRCA1", "CAMK2G", "CAPN2", "CARM1", "CCAR2", "CCDC6", "CCNB1", "CDK1", "CDKN2A", "CERS2", "CLUH", "COL4A3BP", "COLEC12", "COMMD1", "COPS2", "COX15", "COX2", "COX4I1", "COX6C", "COX7A2", "CPT1A", "CPT2", "CRK", "CRTAP", "CSK", "CSNK1A1", "CTNNB1", "CUL2", "CUL3", "CYB5R1", "CYFIP1", "CYFIP2", "CYP51A1", "DCTPP1", "DDX17", "DHCR24", "DHFR", "DNAAF2", "DNM1L", "DNM2", "ECE1", "ECH1", "ECSIT", "EHMT2", "EIF2AK2", "EIF3H", "EIF3J", "EIF4B", "EIF5", "ELP3", "EMD", "EPHX1", "EPS15", "ERBIN", "EXO1", "EXOC6", "FANCD2", "FIS1", "FKBP10", "FMR1", "FOXRED1", "G6PD", "GART", "GNA13", "GNAI1", "GNAI2", "GPAM", "GRB2", "HAT1", "HLA-A", "HLA-C", "HMOX1", "HNRNPF", "ICMT", "ITCH", "ITM2C", "KLC1", "KMT2A", "LMNB1", "LMNB2", "LSS", "LTA4H", "LYN", "MAT2B", "MAVS", "MCM3", "MCM4", "MSMO1", "MTAP", "MTHFD1", "MTMR2", "MTOR", "MTR", "MYH9", "NAA40", "NAE1", "NAMPT", "NCBP2", "NCDN", "ND1", "NDUFA13", "NDUFA2", "NDUFA7", "NDUFA8", "NDUFAF1", "NDUFAF2", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFS6", "NEFL", "NEFM", "NEK9", "NELFCD", "NFATC2IP", "NPC1", "OCLN", "ORC2", "P3H1", "PABPC1", "PAPSS1", "PDK1", "PFDN1", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PMAIP1", "PMPCA", "POLD2", "PON2", "PPAT", "PPP4R1", "PPT2", "PRCC", "PRIM1", "PRKCB", "PRMT1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMD11", "PSME2", "PTPN1", "PXMP2", "RAB4A", "RAB5A", "RABAC1", "RAC1", "RAD50", "RDX", "RP2", "RPS6KA3", "RRM2", "SAMHD1", "SCARB1", "SCARB2", "SCO2", "SDHB", "SFPQ", "SHMT2", "SLC19A1", "SLC25A15", "SLC25A20", "SLC29A1", "SLC2A1", "SLC4A7", "SLIT2", "SMARCB1", "SMC3", "SNW1", "SPNS1", "SPOP", "STAT3", "STRN", "TAB1", "TAP1", "TFAM", "TIGAR", "TIMELESS", "TMEM165", "TMOD1", "TOMM40", "TPM3", "TPM4", "TUBB", "TUBB6", "TUBGCP2", "TYMS", "UBE3A", "UNC119", "USMG5", "UTRN", "VDAC1", "VDAC2", "VIM", "XRCC6", "YBX1", "ZEB2", "ZMPSTE24"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json b/opencell_localization/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..e77640fd2d486c182953c84dda188669948fded5 --- /dev/null +++ b/opencell_localization/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "golgi"} \ No newline at end of file diff --git a/opencell_localization/advanced/plot_0.png b/opencell_localization/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7d53be5ff41fefb877d57c0304e68b5f0b15fdd1 --- /dev/null +++ b/opencell_localization/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5d66827c31c89ec79015c7008d99628bd25c195b044a382065da16b37a65468b +size 198500 diff --git a/opencell_localization/basic/idx2term.json b/opencell_localization/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..2b90cf0aadddc87f8684d2332f9e60420513e6d6 --- /dev/null +++ b/opencell_localization/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "golgi", "1": "vesicles", "2": "cytoskeleton", "3": "membrane"} \ No newline at end of file diff --git a/opencell_localization/basic/plot_0.png b/opencell_localization/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..8c712951765654669d3ed999b82c8195621c01ca --- /dev/null +++ b/opencell_localization/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f948fc561541f0a2a958c2d393dde8d88271d11f490c21616d0c12b974b0e104 +size 123807 diff --git a/opencell_localization/basic/plot_1.png b/opencell_localization/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..13015db8ca2b128b81bcf7bc7f175c49c64e6842 --- /dev/null +++ b/opencell_localization/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e43ae1ab46ffe4de6bf89374c3bcf1f3b791cdff5aba53c0c1e86cb30add4792 +size 137226 diff --git a/opencell_localization/basic/plot_2.png b/opencell_localization/basic/plot_2.png new file mode 100644 index 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https://git-lfs.github.com/spec/v1 +oid sha256:48dd9b8cfa9c8b1982460e70bd8965bc510259d485753e21302f25f89fbe441e +size 68861 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0525fa711957a98dae2f1207eaec67d22ab86a02 --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +golgi 7 58 2.3140396532585874 0.0206655471199024 15.631067961165048 61.19417475728155 0.6692399314943925 0.523533703348586 6.922582002252161 5.868805558877078 1.075539554450533 0.3729249549278102 0.070269142937276 0.0846554635732882 0.0028323971587756 0.0030790050493254 0.0092689304184675 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5b49dfe329cc79ad1491c4fc8d1700d482df2c85 --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 88.94117647058823 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f69d503b7a197c568f11a635225177d1c7a2a41b --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ae1ee2d73e010bb5fb235457888a1ac781160ab0 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,7 @@ 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file mode 100644 index 0000000000000000000000000000000000000000..a4556bbf3d7b2538026aa9afd7413fa864a35911 --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,9 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +transporter 8 56 3.523685074826461 0.0004255897581892 16.281553398058254 57.34708737864078 1.7781248355514696 0.2510912048406951 6.627271511266295 3.5084386843827997 1.4364723564792363 0.3433005081320681 9.928192222865757e-06 1.877054437832283e-05 0.0001278957824949 0.0005338046281504 0.0001493711857724 +protein modifying enzyme 9 24 2.6163016927496665 0.0088887980491652 6.487864077669903 24.82281553398058 0.9737051724681342 0.3238157719208961 2.575528657386725 2.871041189126622 1.1448244681235864 0.2930923238696635 0.2223985575239768 0.2443632781182481 0.107004894081217 0.0129296559640097 0.0004030556375816 +metalloprotease 12 25 2.603076524749289 0.0092391328704342 8.58495145631068 26.398058252427184 1.4262736372921438 0.246779453311036 3.321022586051017 1.6463540525991265 1.1083706824215755 0.2918245458017476 0.0015952289104889 0.0021781449325651 0.0001612622666265 4.204252026569053e-05 1.1798382677149156e-06 +transmembrane signal receptor 3 7 2.4922172397555986 0.0126948365583177 3.266990291262136 7.169902912621359 1.6693846681257831 0.1085289610325799 1.5770125590990791 1.7927217985188668 1.0928815816574815 0.16461969248918 0.0596671413131687 0.0720814043883259 0.058599533767272 0.183699096822524 0.2838535460021641 +oxygenase 2 7 2.4218090802379075 0.0154434617862597 3.138349514563106 6.771844660194175 1.5409868347565758 0.1477866581414416 1.2914149665013366 1.041089559555361 1.2379399582807478 0.2357869798067575 0.0986950754944635 0.1093006244161378 0.0219975904219434 0.0195244436529747 0.1068437246174296 +membrane traffic protein 23 59 2.2936227933100155 0.0218121749778723 17.393203883495147 64.0364077669903 0.6866153002436179 0.5279969401351168 6.983388919650095 8.417857504136053 1.0746394007588131 0.378481933491251 1.0 1.0 0.4276292777269929 0.1601789205270119 0.0142776858958333 +ion channel 1 5 2.2509134781280427 0.0243910179128914 2.0072815533980584 5.492718446601942 0.2992882974166039 0.3902010231102108 1.227692360641773 1.2742579749591922 1.1645136438376027 0.2881631781964495 1.0 1.0 0.2297987482657219 0.1383652025719425 0.3769388356060853 +serine protease 4 18 2.0640723094598545 0.0390108609590844 5.662621359223301 17.516990291262136 1.1445634795625386 0.1820139001244477 2.0809494011218104 1.6626107291843584 1.568325484830445 0.2384821649427795 0.0188245552590614 0.0230489069918226 0.0803922289273931 0.006410021202963 0.0086316463885958 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..daf82fe9429861c533b03e205496b3791555b0a1 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 157, + "title": "Average number of proteins per term", + "value": 13.292993630573248 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..eaa51769ceefaa4597f07cbb13c0be8c21f6a0e7 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ce3214bbfb1bed6f639d1d7dc2f13d7ff33b0f11 --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,54 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +transporter 0.6059957777121656 3.523685074826461 0.0004255897581892 0.0646474991750739 0.0071686833629951 56 Q567V2,O60830,P41440,Q9NR77,Q9Y619,Q99595,Q9Y584,O43772 8 +G-protein coupled receptor 0.9543689320388308 3.5050018934583034 0.0004566040358595 0.0691928861554417 0.0071686833629951 3 Q5VW38,Q9NPR9 2 +deacetylase 0.8547395664833428 3.338974324310332 0.0008408833614432 0.1237240489532293 0.0110015573122162 2 Q6PIU2 1 +viral or transposable element protein 0.762212876091886 2.893487703766843 0.0038098920804534 0.4508015395448195 0.0284834788871996 2 Q9H2J4 1 +tubulin 0.7987055016181124 2.8054642136733534 0.0050244160294674 0.546527972678425 0.0318412223142781 3 P07437,Q9BUF5 2 +extracellular matrix protein 0.8261780805438348 2.682181192593546 0.0073143831249748 0.6841786295127448 0.041214101412925 4 P55081,Q9UFC0 2 +protein modifying enzyme 0.6529284443914705 2.6163016927496665 0.0088887980491652 0.7538417450570479 0.0442426262971047 24 Q92791,Q15102,O60476,Q86YN1,O75718,O60725,P50897,Q9UMR5,P13674 9 +DNA glycosylase 0.7072144936913679 2.615999768394473 0.0088966617933587 0.7541481898903549 0.0442426262971047 2 P29372 1 +metalloprotease 0.6469963871252378 2.6030765247492895 0.0092391328704342 0.7671326512219884 0.0442426262971047 25 Q7Z2K6,Q5JRX3,Q96TA2,Q9UIQ6,P52888,Q9NZ08,P55786,Q9BYT8,Q10713,P42892,P02786,O43847 12 +transmembrane signal receptor 0.8619081330930488 2.4922172397555986 0.0126948365583177 0.8654539028940628 0.0569454097044537 7 Q8WUJ1,Q9UMX5,Q99720 3 +oxygenase 0.8454920110481945 2.4218090802379075 0.0154434617862597 0.9131472227443532 0.065530364876832 7 P09601,P30519 2 +membrane traffic protein 0.4624767234641079 2.2936227933100155 0.0218121749778723 0.968645943617699 0.0878079864493835 59 Q96FZ7,Q00765,Q96PC5,P11717,O00429,Q92734,Q9BXS5,Q9Y2D4,Q13432,P43307,Q9NX40,P30040,Q9BRK0,P50570,Q9UI14,Q8N2H4,Q96D71,Q96RL7,P51572,O14976,P20645,Q9Y2T2,A6NIH7 23 +voltage-gated ion channel 0.6883730120057034 2.2688814730548303 0.0232755346723094 0.9752135462841948 0.0891282669159167 3 P21796 1 +ion channel 0.7744377361441175 2.2509134781280427 0.0243910179128914 0.9792843273920266 0.0899505204687218 5 Q9C0H2 1 +primase 0.6370106761565881 2.247060986256541 0.0246361298099047 0.980085643069036 0.0899505204687218 2 P49642 1 +major histocompatibility complex protein 0.6535958130653214 2.0922131332112723 0.0364194541888778 0.9970459377147974 0.1121147903461532 3 P10321 1 +serine protease 0.6226260673788583 2.0640723094598545 0.0390108609590844 0.9980644639703068 0.1134204661217826 18 O14773,P42785,Q4J6C6,Q9HB40 4 +acyltransferase 0.596242374597132 1.9070597423774245 0.0565128516159374 0.9998919685393014 0.1576558119717352 18 P23786,Q9HCL2,Q9BWD1,Q8NCC3 4 +mitochondrial carrier protein 0.6823794061050432 1.7749623521389566 0.0759041036790071 0.9999958545131687 0.1862022543375643 9 Q70HW3 1 +heterotrimeric G-protein 0.6884034552475568 1.680034622530549 0.0929505796066658 0.9999997771261204 0.217809567138008 6 Q8NHH9,P04899,Q14344 3 +membrane trafficking regulatory protein 0.5397089333999311 1.45138052515228 0.1466739295903436 0.9999999999846872 0.3198306520233882 16 O43760,P24390,Q96AX1,Q14108,Q8WTV0,Q9H267,O43731 7 +nucleotide phosphatase 0.6372586806699951 1.4440463069647882 0.1487259499627464 0.9999999999895072 0.3198626595089204 6 P49902,Q5TFE4,Q9BX68 3 +oxidase 0.5496752514914014 1.4134386614521717 0.1575267847488408 0.9999999999979474 0.3299977350352755 14 O43819,Q6ZRP7,P13073,P14406,Q15800 5 +amino acid transporter 0.5635662597193533 1.413045894833521 0.1576422301123927 0.999999999997991 0.3299977350352755 4 P30825 1 +protease 0.4295146692432826 1.3805989860763177 0.1674022952828038 0.9999999999996776 0.3394319655491316 38 P49721,Q99436,P28070,O75976,P28074 5 +primary active transporter 0.4488669509041542 1.2636769894491229 0.2063459874691475 0.9999999999999998 0.4007581264979448 26 Q15388,Q8N4H5,Q15758,Q6NTF9,P35670,Q9NS69,O75381,Q6P4A7,P09132,P23634,Q96NB2 11 +DNA helicase 0.5592449403690235 1.2625232596936755 0.2067605620785575 1.0 0.4007581264979448 11 P12956,Q96S55 2 +SNARE protein 0.5184835687158998 1.1673524388269552 0.2430680698203913 1.0 0.4489610230800169 13 O15400,Q13277,O60499,Q9P2W9,Q13190,O14653 6 +kinase inhibitor 0.4637540453074486 1.073656831733914 0.2829765158141866 1.0 0.4922082584237456 3 Q96P16,Q5VT52 2 +lyase 0.490171060029227 1.0105909900952557 0.3122122298945642 1.0 0.5105970843067352 13 Q9UHG3,P22830 2 +translation initiation factor 0.3748842279857745 0.945824831953355 0.3442379378386544 1.0 0.5514832269455995 39 O75153,O75822,P55010,P23588 4 +esterase 0.493894731356934 0.8458869845425233 0.3976157939558447 1.0 0.600246919721804 9 Q969T7 1 +basic leucine zipper transcription factor 0.3879003558718851 0.82586870606448 0.4088785742526566 1.0 0.6056031712987462 2 Q9Y6E2 1 +nucleic acid metabolism protein 0.420200712204588 0.6802046221405009 0.4963749060846947 1.0 0.6958112522794382 4 Q96FV9,Q9NYF8,P49750 3 +kinase modulator 0.455618150083184 0.6044912079029051 0.5455171128560996 1.0 0.7383291958483418 6 O00459,P67870,P54619,P13861 4 +ATP-binding cassette (ABC) transporter 0.4070289832853537 0.4889307518868454 0.624890723354538 1.0 0.8108086245178715 11 Q03518,Q8NC96,P08183 3 +actin or actin-binding cytoskeletal protein 0.367166414575138 0.4726802491959793 0.6364413196877035 1.0 0.8138051241511526 17 Q9NYL9,Q15942,P28289,Q6WCQ1,P35241,P14649,O00151 7 +cytoskeletal protein 0.4236563759395442 0.468785496070226 0.639222968171218 1.0 0.8138051241511526 6 Q15019,P27105,Q16181 3 +ATP synthase 0.3385738040742289 0.4333443008312876 0.6647646586872267 1.0 0.8220196816694362 21 Q96IX5,Q9Y487,Q93050,P00846 4 +chaperone 0.2870549198375301 0.3950631490194554 0.6927962842232249 1.0 0.8220196816694362 67 O95456,Q99426,P46379,Q7KZN9 4 +Hsp90 family chaperone 0.3583684040142385 0.3932590892368324 0.6941281310877228 1.0 0.8220196816694362 4 Q12931,P08238,P07900 3 +guanyl-nucleotide exchange factor 0.4046820331698582 0.3926558106715351 0.6945737124722373 1.0 0.8220196816694362 6 Q9Y4G8 1 +oxidoreductase 0.2956410399191583 0.3902379224605254 0.6963606220511784 1.0 0.8220196816694362 48 O15254,P48163,Q9BUP3,O95182,P51970,P00403,O75380,O43678,Q8N0U8,O43676,O43169,O96000,O95831,Q8N4Q0 14 +hydrolase 0.3342583143310522 0.3481824114294415 0.7277031960000087 1.0 0.8358029312321857 19 Q96C86,O60502,Q96CN7,Q9Y3Z3,Q9BPU6,P07099,O43598 7 +histone modifying enzyme 0.3489340388980779 0.3341637120538494 0.7382560251628947 1.0 0.8398999706563367 15 Q03164,Q8WUB8,Q15047 3 +G-protein 0.3485296170475448 0.2669188300617115 0.7895316581770522 1.0 0.8785828073165433 5 Q9NTK5 1 +general transcription factor 0.301709718659179 0.2602878100965197 0.7946417747703767 1.0 0.8785828073165433 29 O75448,Q71SY5,Q16625,P35269,O14776,Q9Y5Q8 6 +kinase 0.3092366427166313 0.1736012694195499 0.862178834318085 1.0 0.9465879509646108 16 Q8TBX8 1 +non-motor microtubule binding protein 0.3100339909299721 0.1366886241252714 0.8912769217621157 1.0 0.9550586391421604 13 Q8WWK9,O94901,Q9BSJ2,P60520,Q9BZD4 5 +dehydrogenase 0.2624829781662323 0.1341722539504511 0.8932663656428628 1.0 0.9550586391421604 70 P49748,Q9P0J0,Q9UBQ7,P48735,Q13423,Q96CU9,Q9BTZ2,P03886,P30837,P53004 10 +GTPase-activating protein 0.3087321298486847 0.1048472217899667 0.9164970389459142 1.0 0.970158063833652 11 Q66K14,Q8N6T3,Q13576 3 +protease inhibitor 0.3066852427761963 0.0839678927240339 0.9330819594833216 1.0 0.970158063833652 8 Q92530 1 +nucleotide kinase 0.2765708550795604 0.0292169493107586 0.976691563408969 1.0 1.0 12 Q13126 1 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c9d4476c5de0df10856637b95de65011b81983e9 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "C4 zinc finger nuclear receptor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "storage protein", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "zinc finger transcription factor"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGPAT1", "AGPAT5", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC7", "ANGEL1", "ANKFY1", "ANLN", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APLP2", "APOB", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARID3B", "ARL1", "ARL6IP5", "ARPC1A", "ARPC3", "ARPC4", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD5", "ATG3", "ATL2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BAP18", "BCAP29", "BCAP31", "BCAS2", "BCAT2", "BCKDHA", "BCKDHB", "BCLAF1", "BLM", "BLMH", "BLVRA", "BOP1", "BPHL", "BRCA1", "BRD1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX8", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKN2AIP", "CEBPZ", "CENPC", "CEPT1", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHDH", "CHEK1", "CHERP", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNP", "COA1", "COA3", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSE1L", "CSGALNACT2", "CSNK1A1", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBT", "DCAF13", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DDT", "DECR1", "DECR2", "DEK", "DENR", "DERL1", "DERL2", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC25", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERH", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESCO2", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FAM3C", "FAM98A", "FAM98B", "FARS2", "FARSA", "FARSB", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDE1", "GDI2", "GDPD1", "GFM2", "GGH", "GID8", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLMN", "GLO1", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLT1B", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HM13", "HMGA1", "HMGCL", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATIP2", "HTRA2", "HUWE1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPAD1", "IMPDH2", "ING5", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "ISCU", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LENG8", "LETM1", "LETMD1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A2", "MAPK1", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "METTL16", "METTL7B", "MFAP1", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKRN2", "MMAB", "MMS19", "MOGS", "MON2", "MORF4L1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKIPSD", "NCOA5", "NCOR1", "ND1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NENF", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NKTR", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA1", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN3", "NSUN4", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC6", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPN1", "PAFAH1B3", "PAFAH2", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PARN", "PARP1", "PARP2", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHC2", "PHF10", "PHF3", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PICALM", "PIGL", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2B", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN9", "PUF60", "PURA", "PUS1", "PWP1", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABAC1", "RAC1", "RACGAP1", "RAD23B", "RAD51C", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM26", "RBM27", "RBM34", "RBM4", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIPK1", "RNASEH2A", "RNF2", "RNMT", "RNPS1", "RP2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35A3", "SLC35B2", "SLC37A4", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPOP", "SPOUT1", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAT1", "STAT3", "STK11IP", "STOM", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TADA3", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRKH", "TECR", "TERF2IP", "TES", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIAL1", "TIGAR", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TJP1", "TK1", "TKT", "TLE3", "TM7SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMOD1", "TMOD3", "TMPO", "TMX2", "TMX3", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1B", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRAP1", "TRIM24", "TRIM27", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TST", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA6", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UBE3A", "UBE3C", "UBIAD1", "UBN1", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UFL1", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", 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0000000000000000000000000000000000000000..d5da3687ec1b819afe36ca81f065f36773b5e3fc --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,13 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +SLC superfamily of solute carriers 13 55 3.429429814004706 0.0006048508458482 18.888349514563107 44.33009708737864 2.1618907004737498 0.1690913715307362 9.633686860107934 5.825351940723624 1.7350998035598977 0.2760301582542676 0.0076435854210874 0.0111376955132978 0.001815615318323 0.0004762934947769 0.0299739114578383 +SLC25 family of mitochondrial transporters 6 25 3.182275555180079 0.0014612272219647 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.0110145064728175 0.0135379522122687 0.0004155585626268 2.4880325513906888e-05 0.0017012881386174 +Receptor 13 26 3.029932174678422 0.0024460866363997 8.25242718446602 27.344660194174757 1.739519175745715 0.1905542238199536 2.855648283399814 4.245230977176689 1.1861053756197322 0.2707159726336181 0.0106202180107422 0.0142331659478869 0.0034901493178882 0.0436986166677031 0.0017136660940566 +Mitochondrial amino acid transporter subfamily 3 7 2.629237532101195 0.0085576563430342 1.75 5.106796116504855 1.5314439851709 0.1644824524943633 1.357512359363716 0.7195281808878056 0.8276270779181836 0.2049815877367878 0.0340178825746634 0.0378187125466048 0.002465796513642 2.1797401302891516e-05 0.0003209969829564 +Metalloprotease 15 35 2.4728680435391617 0.0134033622781115 10.080097087378642 37.81310679611651 1.0846602244748076 0.3802793741361127 4.2814674000125414 2.184793664748831 0.9789887795730944 0.3416347995760264 0.0037785636351715 0.0051240399378157 0.0006633301665035 0.0003656395100037 3.962247606886656e-05 +Transporter 44 201 2.397992198974299 0.0164852163266704 57.59466019417476 188.27912621359224 1.4971900036635353 0.4160578104205245 21.77919356765414 18.57070590158326 1.926868489654782 0.421013047757716 0.1578423962086624 0.2061592057158703 0.002412408312648 0.0001296584454858 4.19984955157054e-05 +Extracellular structure 7 9 2.3930685049922293 0.0167081211629722 2.842233009708738 8.092233009708737 0.8560017356043709 0.3472532488838395 1.4285109580808126 1.0866524100509705 0.962827743376652 0.290186194394739 1.0 1.0 0.0255840399150975 0.0033024410276518 0.0012335596495353 +Translation initiation factor 3 18 2.29319127865583 0.0218369950388119 5.283980582524272 20.803398058252423 0.4565236500219777 0.559881468182603 3.9896024669487 1.082826267249171 0.8934418568512774 0.3359596376002439 0.1141911897347652 0.1263420182810564 0.0293903981750984 0.0294507732567689 0.0437795554968675 +Translation factor 3 23 2.1402599944537672 0.0323337611089333 6.951456310679611 26.34223300970874 0.3217105737724597 0.5885494153132408 5.03989644056169 1.243180568658069 0.9262525781273792 0.3373319193546022 0.159133749222444 0.1755724648168266 0.0563311776114605 0.0720513532108381 0.1254299298894934 +Oxygenase 0 5 2.0101788893517147 0.0444122588897897 1.325242718446602 5.089805825242719 0.6977327730253281 0.3871728673651154 1.2525871050154007 0.6417459204185357 0.96253954683313 0.2912793467281958 1.0 1.0 1.0 0.290751966651369 0.4998540513040848 +SNARE protein 6 12 2.001335437930632 0.0453562531729969 4.555825242718447 10.6626213592233 0.9494792984446184 0.3117420251981136 2.5225757464631977 2.583604188764985 1.1633177546874711 0.3031193116521645 1.0 1.0 1.0 0.4846912912858679 0.0085681988325283 +Acetyltransferase 4 21 1.9638488406253156 0.0495476241904133 5.449029126213592 21.199029126213592 -0.1983462818127869 0.5857201502880531 2.9469128208871305 2.4944986127975195 0.8415601948114603 0.2981313136426305 0.0127949178851295 0.0157111699130222 0.0065760397653667 0.0155108289838298 0.0419614124429943 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..24fe97b76bf28b342f625d47a3800f6959d4c048 --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 1951, + "title": "Average number of proteins per term", + "value": 3.1353152229625834 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..dddf733df3f8dba21a0a08b9d53312c6b92ff32e --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7566c217846694377e1131f4e9a65be8a811d6ed --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,60 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +SLC superfamily of solute carriers 0.6007059484011865 3.429429814004706 0.0006048508458482 0.6928506063761916 0.0018043792052751 55 P30825,Q15758,Q8IXU6,P41440,Q70HW3,O95563,Q9Y619,O43772,Q96H78,Q9BQT8,Q8TBP6,Q9Y6M7,Q86VD7 13 +SLC25 family of mitochondrial transporters 0.7407464749424543 3.182275555180079 0.0014612272219647 0.942325446365444 0.0034347642289797 25 Q70HW3,Q9Y619,O43772,Q96H78,Q8TBP6,Q86VD7 6 +Receptor 0.7107015011506754 3.029932174678422 0.0024460866363997 0.9915885492024306 0.0050129359533781 26 O75787,Q13641,Q567V2,O75381,Q9NR77,Q9UFC0,P20645,P11717,Q13432,A6NIH7,Q14108,Q9UQB8,Q8WTV0 13 +SLC56 Sideroflexins 0.749919120025879 2.8323139776933424 0.004621244653467 0.9998810664241324 0.0081741145230409 2 Q96NB2 1 +Tubulin 0.7987055016181124 2.8054642136733534 0.0050244160294674 0.9999460441659423 0.0086902798523856 3 P07437,Q9BUF5 2 +Mitochondrial amino acid transporter subfamily 0.8942618444897505 2.629237532101195 0.0085576563430342 0.9999999477819173 0.0133996689608827 7 Q8TBP6,O43772,Q9Y619 3 +Glycosylase 0.7072144936913679 2.615999768394473 0.0088966617933587 0.9999999732052426 0.0138416165541012 2 P29372 1 +DNA glycosylase 0.7072144936913679 2.615999768394473 0.0088966617933587 0.9999999732052426 0.0138416165541012 2 P29372 1 +Extracellular matrix glycoprotein 0.7896567675661526 2.5162626279735743 0.0118606764968527 0.9999999999223262 0.017597094939437 4 Q32P28,Q9Y2T2 2 +Metalloprotease 0.581691219495207 2.4728680435391617 0.0134033622781115 0.9999999999963152 0.0195294696076143 35 Q7Z2K6,O75844,Q5JRX3,Q96TA2,Q9UIQ6,P52888,Q9NZ08,P55786,Q9BPU6,Q9BYT8,Q10713,P42892,P02786,O15372,O43847 15 +Cu+-ATPases 0.6677450663215848 2.4106538106802744 0.0159239553364973 0.9999999999999748 0.022447714495308 2 P35670 1 +Transporter 0.3836609842947957 2.397992198974299 0.0164852163266704 0.9999999999999918 0.0230887703182584 201 Q00765,Q8IXU6,Q9NWU2,Q70HW3,O43772,Q9HC07,Q9Y5K8,O14653,P41440,P24390,Q9Y2D4,Q96AX1,Q9Y487,P23634,Q13190,Q9Y6M7,Q9BRK0,P00846,O95563,Q9UI14,Q9Y5P4,Q9Y584,Q9P2W9,Q99808,Q99567,Q96EE3,Q8TBP6,P08183,Q86VD7,P33527,P30825,Q15758,O43760,Q03518,Q9H267,P51572,Q9Y619,Q9NRW7,O15400,P57740,Q96H78,Q9BQT8,Q93050,O43731 44 +Extracellular structure 0.8149558443883071 2.3930685049922293 0.0167081211629722 0.9999999999999948 0.0233339616241652 9 Q92791,Q32P28,O75718,P55081,O43290,Q9Y2T2,Q5KU26 7 +Translation initiation factor 0.66190548702839 2.29319127865583 0.0218369950388119 1.0 0.0292609734345619 18 P55010,O75153,P23588 3 +RSK family 0.6334519572953776 2.2279082188406405 0.0258866360041436 1.0 0.033714837679629 2 P51812 1 +RSK subfamily 0.6334519572953776 2.2279082188406405 0.0258866360041436 1.0 0.033714837679629 2 P51812 1 +Aspartic protease 0.6751083574128551 2.20192599008153 0.0276705367745691 1.0 0.0355399718546308 3 Q5BJF2 1 +Translation factor 0.5823498701840748 2.1402599944537672 0.0323337611089333 1.0 0.0405423150464666 23 O75153,P55010,P23588 3 +SNARE protein 0.6883043634742646 2.001335437930632 0.0453562531729969 1.0 0.0534090522927816 12 O15400,Q13277,O60499,Q9P2W9,Q13190,O14653 6 +Acetyltransferase 0.5706462496084242 1.9638488406253152 0.0495476241904133 1.0 0.0574717091530894 21 P50416,P23786,Q9BWD1,Q8WUB8 4 +Signaling 0.5965921486821447 1.9091571975006123 0.0562418160077846 1.0 0.0641682941702853 18 Q8WUJ1,O15173 2 +Ion channel 0.7159336205650875 1.8883926414857193 0.058973258484726 1.0 0.0667382989000582 8 Q9C0H2,P51790 2 +Phosphatase 0.5074188441322278 1.6839423411279015 0.0921928124264297 1.0 0.0981813193471421 26 Q13614,Q8TF05,Q5TFE4,Q86YN1,P49902,O43681,Q9NPH0,Q9BX68 8 +Heterotrimeric G-protein 0.6884034552475568 1.680034622530549 0.0929505796066658 1.0 0.098934304862305 6 Q8NHH9,P04899,Q14344 3 +Growth factor 0.6499498421091118 1.6707262481634373 0.0947757618358315 1.0 0.1008090132184703 5 Q96PC5,Q7Z4V5 2 +Mitochondrial nucleotide transporter subfamily 0.6381505918448593 1.670526488812327 0.0948152430834921 1.0 0.1008090132184703 11 Q70HW3 1 +DNA helicase 0.6041666775566579 1.638515378283457 0.101314228730327 1.0 0.1076601635364205 13 P25205,P12956,Q96RR1,Q96S55 4 +Protease 0.3721765776087861 1.5811538750138965 0.1138428588104241 1.0 0.1209076851056817 102 P42785,Q8NHP8,Q5JRX3,P61978,Q9NZ08,P55786,P42892,P02786,Q5BJF2,Q96K76,Q7Z2K6,P17655,P48147,Q96TA2,Q5TDH0,O14773,Q9H3G5,Q9UIQ6,P17812,P52888,Q9BYT8,Q92643,Q9HB40,Q10713,Q66K14,O43847 26 +Nucleotide phosphatase 0.6458925154548666 1.5566885950622178 0.1195444377413792 1.0 0.1268940141639994 8 P49902,O43681,Q5TFE4,Q9BX68 4 +Helicase 0.4966090896690349 1.5478729278151642 0.1216528937667202 1.0 0.1290618791402236 22 P12956,P42694,Q96S55,Q96RR1,P25205 5 +Guanyl-nucleotide exchange factor 0.536607378470721 1.472786419540938 0.1408086353467408 1.0 0.1490600366584326 3 Q9Y4G8 1 +AGC group 0.5836027931268395 1.2225928393289356 0.2214835190485649 1.0 0.2331971644164868 7 P31751 1 +G-protein 0.4331133618438547 1.2113057181086488 0.2257782580589458 1.0 0.2375908206434753 30 Q9UI26,P50570,Q16181,Q14344,Q15019,O60313,Q96P70,O95373,O00429,Q9NTK5,P62070,Q8NHH9,P04899,P84095 14 +Enzyme modulator 0.3389813596125686 1.112253748960208 0.2660290638558966 1.0 0.2790444642918572 100 P46379,Q13576,Q16181,P55209,Q9NTK5,Q9Y4G8,Q9UJZ1,P84095,O00459,Q99733,P04899,Q92530,P50570,Q96F07,Q06481,P27105,Q96D71,P14635,P53367,Q14C86,Q96P70,Q6WCQ1,Q8NHH9 23 +Esterase 0.5192736231246223 1.109747721545554 0.2671077526109677 1.0 0.280025376326705 12 Q9UMR5,Q8IY17,Q969T7 3 +CDK family 0.5252590673575114 1.0620531450670867 0.288211559347598 1.0 0.3018254172233836 5 P11802,P50750,Q00535,P06493 4 +TK group 0.5225306662582987 1.0486552926636838 0.2943367976385576 1.0 0.3075795887481659 5 P07948,Q15375 2 +G-protein modulator 0.4210591110369751 1.0406845316119857 0.2980219845782668 1.0 0.3112638607667015 24 Q14C86,Q96F07,P53367,Q9Y4G8 4 +Miscellaneous SLC25 mitochondrial transporters 0.4208993853121968 1.0172772566460098 0.3090215527970077 1.0 0.322407549807761 2 Q9Y6C9 1 +Membrane trafficking regulatory protein 0.4555367946657291 0.9914641100488416 0.3214590089301734 1.0 0.3350248538583164 17 O43760,P24390,Q96AX1,Q9NRW7,Q96EE3,Q9H267,O43731 7 +mRNA splicing factor 0.3385954488619236 0.9758949290260588 0.3291165353239482 1.0 0.3426394666046014 62 P09661,P62310,P62995,Q13247,Q15233,Q15637,Q9Y4Y9,O75525,Q8IWZ8,O75494,O43395,P98179,P62312,Q16629,Q8IY67,P38159,Q9UK45,Q8WWY3,Q14011,Q96E39,Q92804,Q8WXF1,P35637,Q07666,Q96PU8 25 +Protease inhibitor 0.5096026917296012 0.9541156673850024 0.3400250962983249 1.0 0.3536188501482046 10 Q06481,P27105,Q92530 3 +SLC12 family of cation-coupled chloride transporters 0.4047233904885106 0.9230209793559896 0.3559962723647376 1.0 0.3696374280913268 2 P55011 1 +Dehydrogenase 0.3202774224048318 0.7808216634359734 0.4349073908103809 1.0 0.4484695134625016 61 O95831,Q8N4Q0,P30837,P03886 4 +Immune response 0.481699203991197 0.7203445488490873 0.4713128822788364 1.0 0.4844738847871495 6 Q9NX40 1 +Oxidase 0.3844262522927499 0.6377676665715001 0.5236249301174594 1.0 0.5359875333993511 19 O15254,P49748,O43819,Q6ZRP7,P14406,Q15800 6 +V-type ATPase 0.4420844327477724 0.5783995334579828 0.5629944088653216 1.0 0.5759843165685592 8 Q93050,Q9Y487 2 +Kinase modulator 0.413271081002979 0.5545097309585206 0.5792300479061994 1.0 0.5922839745623664 12 O00459,P14635,Q15942 3 +Small GTPase 0.3481679247295599 0.5336442214692775 0.5935877069487994 1.0 0.6066472583850747 23 Q9UI26,P50570,Q16181,Q15019,O60313,O95373,O00429,Q96P70,P84095 9 +Protein arginine methyltransferase 0.3884309293185447 0.5279375849466302 0.5975426570364035 1.0 0.6100500909879766 4 Q86X55 1 +F-type and V-type ATPases 0.362582857759431 0.4477902277375953 0.6543045967228498 1.0 0.6662569249510856 17 Q93050,Q9Y487,P00846 3 +Hsp90 family chaperone 0.3583684040142385 0.3932590892368324 0.6941281310877228 1.0 0.7049682372473436 4 Q12931,P08238,P07900 3 +Non-protein kinase 0.3470798257708399 0.3253718705963896 0.7448996422895768 1.0 0.7545686407616637 15 Q8TBX8 1 +ABCB subfamily 0.3852301951496759 0.3189660129557766 0.7497522854092082 1.0 0.7590901446981657 6 P08183 1 +ATP-binding cassette transporter family 0.3562816983145119 0.2310988621890904 0.8172379990390723 1.0 0.8235699050233627 8 Q03518,P08183 2 +Non-motor microtubule binding protein 0.3451929716217037 0.2266183095748108 0.8207205536871611 1.0 0.8266524523715288 11 O94901,P60520 2 +Hydrolase 0.2718811081945025 0.193239181526532 0.8467716545586381 1.0 0.8520121186404863 89 Q13614,Q8TF05,Q8IY17,Q969T7,Q8NCC3,Q9NPH0,Q9UMR5 7 +Oxidoreductase 0.2566166943423684 0.1750729290540063 0.8610223292155261 1.0 0.8659044145873668 120 P49748,O15254,Q9P0J0,Q9UBQ7,Q13423,O43819,P30837,P51970,Q96CU9,Q15392,Q6ZRP7,P53004,P03886,Q16850,P14406,O95831,Q15800,Q8N4Q0 18 +Cysteine protease 0.261587577452939 0.0495224497055382 0.9605029468691736 1.0 0.9629708372773677 32 P17655,Q8NHP8,P17812,Q66K14,Q96K76 5 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..69ee5109397592fac84a9668f01ed06d5d7ea1ef --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2,4-dienoyl-CoA reductase, mitochondrial", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L41, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-aminobutyrate aminotransferase, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-1", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-methylcytosine rRNA methyltransferase NSUN4", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-1 complex subunit sigma-2", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP synthase-coupling factor 6, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family B member 8, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family D member 4", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase WRNIP1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "AUR family", "Abl interactor 1", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A synthetase 2-like, mitochondrial", "Acetyl-coenzyme A transporter 1", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Activating signal cointegrator 1", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine aminotransferase 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amyloid-like protein 2", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Anion exchange protein 2", "Anion exchangers", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Antigen peptide transporter 2", "Apoptosis regulator BAX", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arginase-2, mitochondrial", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical group", "Aurora kinase a", "Aurora kinase b", "B-cell receptor-associated protein 29", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2 homologous antagonist/killer", "Bcl-2-associated transcription factor 1", "Beta-galactosidase", "Beta-galactosidase-1-like protein 2", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 3", "Bromodomain-containing protein 4", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CDKN2A-interacting protein", "CHK1 subfamily", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CMGC group", "COMM domain-containing protein 5", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "COUP-TF-like receptors", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carbonyl reductase family member 4", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Cat eye syndrome critical region protein 2", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere protein C", "Centromere/kinetochore protein zw10 homolog", "Chaperone", "Chaperonin", "Charged multivesicular body protein 6", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Choline dehydrogenase, mitochondrial", "Choline transporter-like protein 1", "Choline/ethanolaminephosphotransferase 1", "Chondroitin sulfate N-acetylgalactosaminyltransferase 2", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 2", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 4", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collagen type IV alpha-3-binding protein", "Collectin-12", "Condensin complex subunit 1", "Copper-transporting ATPase 1", "Copper-transporting ATPase 2", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1C", "Coup transcription factor 2", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cu+-ATPases", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystatin-B", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DCK/DGK family", "DDB1- and CUL4-associated factor 13", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA topoisomerase 3-alpha", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(14)-sterol reductase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxyguanosine kinase, mitochondrial", "Deoxyribonuclease-2-alpha", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Derlin-2", "Desmocollin-1", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Dna-dependent protein kinase catalytic subunit", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase ZNF598", "EF-hand domain-containing protein D1", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER lumen protein-retaining receptor 3", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "ERO1-like protein beta", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endonuclease III-like protein 1", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 7", "Epidermal growth factor receptor substrate 15", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Estradiol 17-beta-dehydrogenase 8", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 1", "Exocyst complex component 3", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 6B", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferritin light chain", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Folate transporter 1", "Fragile X mental retardation syndrome-related protein 1", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "GC-rich sequence DNA-binding factor 2", "GDP-fucose protein O-fucosyltransferase 2", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General vesicular transport factor p115", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate exchanger SLC37A4", "Glucose-6-phosphate isomerase", "Glucose-induced degradation protein 8 homolog", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase catalytic subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--tRNA ligase", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi SNAP receptor complex member 2", "Golgi pH regulator family", "Golgi ph regulator b", "Graves disease carrier protein", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "H/ACA ribonucleoprotein complex subunit 3", "HBS1-like protein", "HDAC class I", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histidine triad nucleotide-binding protein 3", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase NSD3", "Histone-lysine N-methyltransferase SETD2", "Histone-lysine N-methyltransferase SMYD3", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "ILK subfamily", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of growth protein 5", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 3", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF18B", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIFC1", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LETM1 domain-containing protein 1", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Legumain", "Lethal(3)malignant brain tumor-like protein 3", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophosphatidylcholine acyltransferase 2", "Lysophospholipid acyltransferase 5", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "M-phase phosphoprotein 8", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAPK family", "MBT domain", "MCU family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB", "Mediator of RNA polymerase II transcription subunit 12", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 20", "Mediator of RNA polymerase II transcription subunit 25", "Mediator of RNA polymerase II transcription subunit 27", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine--tRNA ligase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Methyltransferase-like protein 7B", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial coenzyme A transporter SLC25A42", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import inner membrane translocase subunit Tim22", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multifunctional protein ADE2", "Muscleblind-like protein 1", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light chain 6B", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 12", "Myotubularin-related protein 2", "N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 50", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral cholesterol ester hydrolase 1", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear cap-binding protein subunit 2", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor", "Nuclear receptor coactivator 5", "Nuclear receptor corepressor 1", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase 6", "Nucleoside diphosphate kinase A", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "OCIA domain-containing protein 1", "Obg-like ATPase 1", "Occludin", "Origin recognition complex subunit 2", "Origin recognition complex subunit 3", "Origin recognition complex subunit 6", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P53-like transcription factor", "PAKB subfamily", "PAX3- and PAX7-binding protein 1", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PKC alpha subfamily", "PKC family", "PKN family", "PLK family", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 3", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal 2,4-dienoyl-CoA reductase", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal bifunctional enzyme", "Peroxisomal biogenesis factor 19", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phenylalanine--tRNA ligase, mitochondrial", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 3-kinase regulatory subunit beta", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylated adapter RNA export protein", "Plasma membrane calcium-transporting ATPase 1", "Plasma membrane calcium-transporting ATPase 4", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Platelet-activating factor acetylhydrolase 2, cytoplasmic", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polyhomeotic-like protein 2", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Pre-mRNA cleavage complex 2 protein Pcf11", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Prenylated Rab acceptor protein 1", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX37", "Probable E3 ubiquitin-protein ligase makorin-2", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable cysteine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable helicase with zinc finger domain", "Probable histidine--tRNA ligase, mitochondrial", "Probable leucine--tRNA ligase, mitochondrial", "Probable ribosome biogenesis protein RLP24", "Probable serine carboxypeptidase CPVL", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein NDRG3", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein S100-A13", "Protein SCAF8", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SYS1 homolog", "Protein Wiz", "Protein XRP2", "Protein angel homolog 1", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein gpr107", "Protein kinase", "Protein kinase c alpha type", "Protein kinase c beta type", "Protein lin-9 homolog", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1G", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec23B", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog A", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pterin-4-alpha-carbinolamine dehydratase", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RIPK family", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA polymerase II elongation factor ELL", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein FUS", "RNA-binding protein Nova-1", "RNA-binding protein with serine-rich domain 1", "RNA/RNP complex-1-interacting phosphatase", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor beta", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein R-Ras2", "Ras-related protein Ral-A", "Reader", "Receptor", "Receptor expression-enhancing protein 2", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Recombining binding protein suppressor of hairless", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinoic acid-induced protein 1", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal RNA-processing protein 7 homolog A", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "Ribosome-releasing factor 2, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "SAP30-binding protein", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC33 acetylCoA transporter", "SLC35 family of nucleotide sugar transporters", "SLC37 family of phosphosugar/phosphate exchangers", "SLC4 family of bicarbonate transporters", "SLC44 choline transporter-like family", "SLC5 family of sodium-dependent glucose transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STE group", "STE20 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Secretory carrier-associated membrane protein 4", "Sentrin-specific protease 3", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 11-interacting protein", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase chk1", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters", "Sodium-dependent HCO3- transporters", "Sodium-dependent multivitamin transporter", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 9", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 25 member 33", "Solute carrier family 25 member 40", "Solute carrier family 25 member 44", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 23", "Syntaxin-10", "Syntaxin-12", "Syntaxin-18", "Syntaxin-3", "Syntaxin-5", "Syntaxin-6", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "Syntenin-1", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TOPK family", "TP53-binding protein 1", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Testin", "Testis-specific Y-encoded-like protein 1", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Torsin-1A", "Torsin-1B", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription factor 20", "Transcription initiation factor IIB", "Transcription initiation factor TFIID subunit 9B", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor CTCF", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transducin-like enhancer protein 3", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation release factor", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 4", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Trypsin-3", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2B chain", "Tubulin beta-6 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase lyn", "Tyrosine-protein kinase yes", "Tyrosine-protein phosphatase non-receptor type 9", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP4", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm3", "U6 snRNA-associated Sm-like protein LSm4", "U6 snRNA-associated Sm-like protein LSm5", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "UDP-N-acetylglucosamine transporter", "UDP-glucose:glycoprotein glucosyltransferase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "UbiA prenyltransferase domain-containing protein 1", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 36", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Very long-chain acyl-CoA synthetase", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WEE family", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YLP motif-containing protein 1", "YSK subfamily", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCHC domain-containing protein 8", "Zinc finger E-box-binding homeobox 2", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 148", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein 644", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 5", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial", "tRNA pseudouridine synthase A"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG12", "ALYREF", "ANAPC1", "ANGEL1", "ANO6", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APLP2", "ARCN1", "ARFIP1", "ARG2", "ARHGDIA", "ARID3B", "ARPC1A", "ARPC3", "ARPC4", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATIC", "ATL2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "BAG6", "BAIAP2", "BAK1", "BAX", "BCAP29", "BCAP31", "BCAS2", "BCAT2", "BCKDHB", "BCLAF1", "BLMH", "BLVRA", "BOP1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIX1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC37", "CDC40", "CDC42", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKN2AIP", "CEBPZ", "CECR2", "CENPC", "CEPT1", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHDH", "CHEK1", "CHERP", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNP", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPOX", "CPSF1", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBT", "DCAF13", "DCPS", "DCTN1", "DCTN2", "DDB1", "DDI2", "DDOST", "DDT", "DECR1", "DECR2", "DENR", "DERL1", "DERL2", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIS3", "DLD", "DLST", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUSP11", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "EPHA7", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERH", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FAM177A1", "FARS2", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FOXRED1", "FSCN1", "FTL", "FUBP1", "FUBP3", "FUS", "FXR1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GCAT", "GCFC2", "GCLC", "GCN1", "GDI2", "GFM2", "GGH", "GID8", "GLB1", "GLB1L2", "GLDC", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNPDA1", "GNS", "GOSR1", "GOSR2", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPR107", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2F2", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HEATR1", "HEATR6", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HPRT1", "HSD17B10", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPAD1", "IMPDH2", "ING5", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "IVD", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LETMD1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LRRC47", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LYN", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A2", "MAPK1", "MAPRE1", "MAPRE2", "MARCH5", "MARS2", "MAT2A", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED12", "MED14", "MED20", "MED25", "MED27", "METTL7B", "MFAP1", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MKRN2", "MMS19", "MORF4L1", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL14", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL38", "MRPL39", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL48", "MRPL49", "MRPL9", "MRPS11", "MRPS16", "MRPS18A", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA50", "NADK2", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCBP1", "NCBP2", "NCEH1", "NCL", "NCOA5", "NCOR1", "ND1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEDD4L", "NEK9", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA1", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN3", "NSUN4", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCLN", "OLA1", "OPA1", "ORC2", "ORC3", "ORC6", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "PAFAH2", "PAICS", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDHX", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF10", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIK3C2A", "PIK3R2", "PIK3R4", "PINX1", "PIP4K2C", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNP", "PNPLA6", "PNPT1", "POFUT2", "POGZ", "POLA2", "POLD2", "POLDIP3", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL3", "PPM1G", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA1", "PRKAA2", "PRKAG1", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2B", "PRRC2C", "PRSS3", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPN9", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "RAB3GAP2", "RABAC1", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIPK1", "RNASEH2A", "RNH1", "RNPS1", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "S100A10", "S100A11", "S100A13", "SAE1", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIN3A", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMN1*", "SMYD3", "SNAP23", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SPAG9", "SPCS2", "SPCS3", "SPNS1", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAT1", "STAT3", "STK11IP", "STK26", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUPT16H", "SUPT6H", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM22", "TJP1", "TK1", "TKT", "TLE3", "TM7SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM165", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOP3A", "TOR1A", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRIP4", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TST", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA6", "UBE2L3", "UBIAD1", "UCHL5", "UGGT1", "UNC119", "UNC119B", "UPF1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP5", "USP7", "UTP11", "UTP14A", "UTP3", "UTP6", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VRK1", "VRK2", "WARS", "WDHD1", "WDR1", "WDR33", "WDR74", "WDR82", "WIZ", "WRNIP1", "XAB2", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS2", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZCCHC8", "ZEB2", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF148", "ZNF281", "ZNF598", "ZNF622", "ZNF644", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCC1", "ACADVL", "ACAT2", "ACOX3", "ACP6", "AIFM1", "AKT2", "ALDH1B1", "AP3M1", "APLP2", "ARFIP1", "ASNA1", "ATL2", "ATP2B4", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP7B", "BAG6", "BAIAP2", "BCAP31", "BLVRA", "CAPN2", "CARM1", "CCNB1", "CDK1", "CDK4", "CDK5", "CDK9", "CIRBP", "CLCN3", "CLUH", "COL4A3BP", "COLEC12", "COX7A2", "CPT1A", "CPT2", "CPVL", "CRTAP", "CTPS1", "CYB5D2", "CYFIP2", "CYP51A1", "DDI2", "DHCR24", "DNM1L", "DNM2", "DOLPP1", "DPYSL5", "ECE1", "EIF3H", "EIF4B", "EIF5", "EPHA7", "ERAP1", "ERMP1", "EXOC6B", "FOXRED1", "FUS", "GABARAPL2", "GAPVD1", "GID8", "GNA13", "GNAI2", "GOSR2", "GRHPR", "HDGFL2", "HELZ", "HINT2", "HNRNPK", "HSP90AA1", "HSP90AB1", "IGF2R", "IPO11", "IPO7", "IPO9", "IQGAP2", "KDELR1", "KDELR3", "KHDRBS1", "KHDRBS3", "LNPEP", "LRWD1", "LSM3", "LSM5", "LSM6", "LSM7", "LYN", "M6PR", "MCM3", "MFAP1", "MIA2", "MPC2", "MPG", "MPRIP", "MPV17L2", "MSMO1", "MTCH2", "MTMR2", "NAP1L1", "NAP1L4", "ND1", "NDUFA13", "NDUFA8", "NLN", "NNT", "NONO", "NPEPPS", "NRDC", "NT5C2", "NT5C3B", "NT5DC1", "NUP107", "NUP88", "OCIAD1", "OLA1", "OPA1", "P3H1", "P3H4", "PEX14", "PGRMC2", "PHF10", "PIGK", "PIK3R2", "PIP4K2C", "PITRM1", "PLA2G15", "PLBD2", "PMPCA", "PNPLA6", "PPP4R1", "PPT2", "PRCP", "PREP", "PRPF3", "PRPF31", "PSMF1", "PSPC1", "PXMP2", "QKI", "QSOX2", "RABAC1", "RAPGEF2", "RAVER1", "RBM3", "RBMX", "RBMXL1", "REEP2", "REEP5", "REPS1", "RHOG", "RPS6KA3", "RRAS2", "SART1", "SCARB1", "SCARB2", "SCO2", "SCPEP1", "SEH1L", "SEPT2", "SEPT7", "SF1", "SFXN2", "SLC12A2", "SLC19A1", "SLC1A5", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A40", "SLC25A42", "SLC25A44", "SLC29A1", "SLC35F2", "SLC4A7", "SLC7A1", "SNRPA1", "SRSF10", "SRSF6", "SRSF7", "STOM", "STOML2", "STX10", "STX18", "STX3", "STX5", "STX7", "SUGP1", "SUN1", "SYNGR2", "TAF15", "TAP1", "TBC1D9B", "TFRC", "THOP1", "TIMM22", "TMEM165", "TMEM97", "TPBG", "TPP1", "TRA2B", "TRAP1", "TTYH3", "TUBB", "TUBB6", "TWNK", "UNC119", "UNC119B", "USP47", "VPS33A", "VPS33B", "VPS45", "WRNIP1", "XRCC6", "YME1L1", "ZADH2", "ZMPSTE24", "ZYX"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..61535a796704ebaa5615648b4b855d9c5c3c7f08 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tdark", "1": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a6f88c50eae389c5866a3b9fe45102cdb7301804 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a528dc193db1adf42ab1045386ce6bd85d4f3842055cb222b37d67aeb1a5e6f1 +size 131715 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..7450bc6bc0d4fc1612eac514c361ea9566220392 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:67b8a984beaeee2f0766edfde4d328cbc1d97373ddf066c6f7b9b699ece50b49 +size 132441 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..bbbda02a78b37be744c7069fe925e3ac58582e3e --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b1e5478049b0440050f80a01559310503c8f4db1191527adb2bc5fc526b706a9 +size 68126 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..504756511ed369e892237a5cbe783cbb13fe474a --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 773.0 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8b3b9512ad27c938aa0b20ef6455a5d5503dbd47 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4c80ad02cdacca1d45f7782aaefba8934494818c --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tdark 0.3124496649749341 1.8544769899824856 0.0636709491219684 0.2313759085858615 0.1494210419008726 346 Q8WUJ1,Q9HD20,Q8IXU6,A4D1U4,O60830,Q86YN1,Q5VW38,P0CG08,Q69YU5,P14406,Q8NC96,Q7Z2K6,Q8N4H5,Q9H0E3,Q96HH6,Q9Y4Y9,Q5TFE4,O60476,Q9NR77,Q96CP7,Q9NRY5,Q9NPR9,P14649,Q96M27,Q9NSI2,Q96IX5,Q9BTE7,Q4VC44,Q9BRK0,Q92575,Q9P260,Q969T7,Q9H910,Q9NU23,Q8TBP6,Q9Y5Q8,Q96CN7,Q9P0S9,Q8NBM8,Q96H78,Q5SWX8,O95302,Q66K14,Q8N6N3,Q96DB5,O43731 46 +Tclin 0.3976799818080201 1.658838612592769 0.0971483173260523 0.335544887794897 0.1494210419008726 79 Q9P0J0,P49721,Q99720,O75380,P14324,P03886,Q9BUF5,O96000,O95182,P07437,Q9Y375,O43676,P28074,P51970,P20618,Q99808,P38435,P07948,P48735,Q8N183,P31350,Q9BVA1,P21964,O43678 24 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..093d97c700b978381fe629136ea12caaeae9cc5d --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf35", "C1orf52", "C2CD5", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf33", "CAAP1", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC59", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPI", "CENPL", "CENPP", "CENPQ", "CENPU", "CENPV", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM114A2", "FAM120A", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM207A", "FAM208A", "FAM208B", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMC1", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LETMD1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM12", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "M6PR", "MACF1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NEPRO", "NES", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2B", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "ROMO1", "RP2", "RPA1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RSRC1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35A4", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPNS1", "SPOP", "SPOUT1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THEM6", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THYN1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF3", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED8", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM19", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM223", "TMEM230", "TMEM245", "TMEM33", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBFD1", "UBIAD1", "UBN1", "UBQLN4", "UBR4", 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sha256:346b5cd5b70fda3e53c1940c4d5f29bb20ef858d5655bdb50b00ae683f063ddb +size 147517 diff --git a/protein_atlas_biological_process/consensus.joblib b/protein_atlas_biological_process/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..fcc35f37e8996e6e2b42d6c8668d2021cfb7631a --- /dev/null +++ b/protein_atlas_biological_process/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a012e6708bbdb8edc748cc1eecd9b6d9dfeae0b1d9e7ed83533dd52b9df08533 +size 97642 diff --git a/protein_atlas_biological_process/df_merge.tsv b/protein_atlas_biological_process/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e699045caf5dd6ec1b8e06d0ef7db68ff45e6461 --- /dev/null +++ b/protein_atlas_biological_process/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 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1.9171930478617292 1.3907470472448622 1.1684874391815692 0.271335812648974 1.0 1.0 1.0 0.0322769586697076 0.0489208457435743 +Lipid transport 5 22 1.9630842024929365 0.0496363908406103 5.140776699029126 21.796116504854368 0.7022879686929654 0.35525802853007 2.5598823127228028 3.5727100026626353 1.209238263022456 0.2984698606617377 0.0318830002952024 0.0388410242837302 0.1290920553826253 0.0203556588144228 0.0363470309637756 diff --git a/protein_atlas_biological_process/metrics.json b/protein_atlas_biological_process/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..bd7bf027a6e04a0f11e5c7e7f47b87db92418579 --- /dev/null +++ b/protein_atlas_biological_process/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 173, + "title": "Average number of proteins per term", + "value": 29.69942196531792 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..adbe76c8e860e512a93b5f38481a1508585d1257 --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c547d24171bee597b30c680b9cce25687efc4c92 --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,49 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transport 0.3777971971827393 3.4576897507322237 0.0005448284143678 0.0899729926479006 0.0067325225489744 500 Q9BZF3,P46379,Q8IXU6,O60830,Q70HW3,Q99720,O60831,O75380,Q99595,P23786,O75396,O43772,P36405,P03886,Q92734,Q15388,Q8N4H5,Q8NHS3,Q9UI26,P41440,Q9BXS5,Q6P4Q7,O75964,O43676,O60749,Q9C0H2,Q9Y2D2,Q9NVJ2,P00846,O95563,P00403,O43615,Q96CU9,O94979,O15127,Q9Y584,Q8TBP6,P08183,Q86VD7,O00461,P30825,P31751,Q9Y619,P51790,A6NIH7,P62072,Q96H78,Q9BQT8,O43731,Q9HD20,P0CG08,O15118,Q8NC96,O14653,Q5BJH7,P24390,Q6DKK2,Q6IQ22,Q9Y487,Q16629,P23634,Q9Y6M7,Q9Y5P4,Q9P260,Q6WKZ4,Q96EE3,Q9Y2V7,Q96RL7,Q15758,P50416,Q9Y282,P52298,Q93050,Q9P0J0,Q9NS69,P11717,P04114,O96000,O95182,Q13505,Q13432,Q9Y3Y2,P51970,Q12981,O43823,O15126,P83436,Q03518,Q9H814,P60520,P51572,P20645,P57740,Q9H267,Q96P70,Q8TDW0,P21796,Q6P4A7,Q9Y5K8,O00459,P49321,Q9Y2D4,Q96AX1,P45880,O43681,O43169,Q13190,Q4KMQ2,O75381,Q9UP83,Q9P2W9,Q99808,Q99567,P33527,O15504,Q9NRW7,Q9NUL3,Q9Y2T2,O60499,O43678 120 +DNA excision 0.9175276975112528 3.345049218779032 0.0008226796983972 0.1327102531792993 0.0088952242389199 3 Q9UQ84 1 +Biomineralization 0.6881268197994241 2.5173533379399635 0.011824018492337 0.8722582615680281 0.0454898012501776 2 Q6P4Q7 1 +Purine salvage 0.8324511075236293 2.5088674387678784 0.0121118927641818 0.878537562693133 0.0454898012501776 5 P55263 1 +Copper transport 0.6677450663215848 2.4106538106802744 0.0159239553364973 0.9377759656425466 0.0547376526107169 2 P35670 1 +Neurogenesis 0.5252790270135781 2.297536872243851 0.0215881621531783 0.9770779286985202 0.0691620750462937 41 Q8WUJ1,O94813,Q99426,Q9Y4G8,Q8WUB8 5 +Amino-acid transport 0.7459961215148457 1.9822073111250156 0.0474560427454942 0.9997776129219744 0.1294835441938033 7 P30825,Q15758,Q96H78 3 +Lipid transport 0.5581298962271463 1.9630842024929365 0.0496363908406103 0.9998503987977406 0.1301075093246301 22 Q9BZF3,Q9Y5P4,Q99720,Q9P260,O15118 5 +DNA synthesis 0.6132189872067831 1.8825961285079855 0.0597551214519769 0.999976520494867 0.1498208117564059 3 P04183 1 +Cell shape 0.6746674199816601 1.78867419230068 0.0736673015780784 0.9999982188929216 0.1677398526757128 5 P15311,P35580,P35579 3 +Apoptosis 0.365532004161943 1.7870307089433843 0.0739325253703202 0.9999983049785766 0.1677398526757128 118 P46379,Q9P0J0,Q9UDX5,Q9BUP3,P21796,Q03164,Q9Y3D6,P23396,O95470,O95831,O95817,Q9BX68,Q96J02,Q6FI81,O43464,Q96F07,P09601,Q15375,Q12981,Q13794,P05771,Q9NXR7,Q8N163,P31751,P51572,Q9UHR5,Q9H2J4 27 +Methionine biosynthesis 0.5792880258899544 1.7028864817835534 0.0885893143079246 0.9999998927142396 0.1846500165695296 3 Q99707,Q9BV57 2 +Meiosis 0.588985719413928 1.6351783382398233 0.1020116677524487 0.9999999917618436 0.2076237473079251 14 O94901,Q9UQ84 2 +Antiport 0.6577032600763881 1.6132740766940858 0.1066849759621262 0.9999999966595698 0.2078873185120597 8 P41440 1 +Symport 0.6645495958770122 1.6065885297539917 0.1081446603427074 0.999999997482705 0.2078873185120597 7 Q9Y6M7 1 +Vision 0.6723850714357072 1.606566609944115 0.1081494720582969 0.9999999974850534 0.2078873185120597 6 Q13432,Q6P4Q7,Q9H6K4,P50897 4 +Sensory transduction 0.6723850714357072 1.606566609944115 0.1081494720582969 0.9999999974850534 0.2078873185120597 6 Q13432,Q6P4Q7,Q9H6K4,P50897 4 +Immunity 0.3821619318671398 1.4469337174944792 0.1479154885692941 0.9999999999990592 0.2665560366925822 68 P07948,Q96J02,P46379,Q03518,Q14166,P12956,P17812,P04439,Q9UQ84,Q96S55,Q9NZ08,Q9Y3Z3,O43823,P05771,Q92974,P10321 16 +Protein transport 0.3134561455749221 1.4296859888177404 0.1528071633766499 0.9999999999996524 0.2697514210628615 241 Q9HD20,Q96FZ7,Q9UBU9,O60830,Q9NS69,Q6NUQ1,O60831,P0CG08,Q99595,P36405,O75396,O15027,P20338,Q8NC96,O14653,Q15388,Q8N4H5,Q5BJH7,O00459,Q9UI26,Q9BXS5,P24390,P49321,Q9Y2D4,O00410,Q13505,O60826,Q6IQ22,Q96AX1,Q13432,O60749,Q8N6T3,Q9NVJ2,Q7Z3B4,O75381,O43615,O94979,O15127,Q6WKZ4,Q9Y584,Q9P2W9,Q9UP83,O43823,Q96EE3,Q9Y2V7,Q99567,O15126,Q96RL7,P83436,O15504,Q03518,Q9H814,P60520,Q92538,P51572,Q8N1F7,Q96P70,Q9NRW7,Q9Y2T2,A6NIH7,P57740,P62072,O60499,Q9H267,O75431,O43731 66 +Heme biosynthesis 0.6262770338884784 1.3928988265174729 0.1636503873547157 0.9999999999999626 0.2803120496273843 6 P22830 1 +Sugar transport 0.5422279630952329 1.303298876743055 0.1924727444416154 1.0 0.3201710075807641 4 Q9Y2D2,P31751 2 +Translocation 0.3819955565994975 1.1957068546750198 0.2318109754693285 1.0 0.3819361786304174 48 O60830,Q9NS69,O75381,Q99595,Q9Y584,P57740,P62072,Q99567,Q96EE3 9 +Pentose shunt 0.4296344225169841 1.0683820907668014 0.2853481922146648 1.0 0.4613573575059533 2 P52209 1 +Adaptive immunity 0.4755525768756924 0.990450847330971 0.3219538027258029 1.0 0.5017838546987738 14 P07948,Q03518,Q9NZ08,P05771,P10321 5 +Steroid biosynthesis 0.4119124145398943 0.9758698007959852 0.329128989143542 1.0 0.5083867421592212 24 Q9UHQ9,Q53GQ0,P48449,Q9H3P7,P14324,Q15392,Q16850,Q15800 8 +Respiratory chain 0.3907869314058384 0.958964317929314 0.3375767211170464 1.0 0.5168209978163631 34 Q9P0J0,O95182,P51970,Q6DKK2,P00403,O75380,Q96CU9,O43678,P03886,O43676,O95168,O96000 12 +Lipid degradation 0.4680594728529144 0.9478382685743144 0.3432117953023761 1.0 0.5208389525202726 14 Q8IY17,Q9H6V9,Q8NHP8,Q8NCC3,Q6PIU2 5 +Ion transport 0.3264763502496996 0.8480773415342627 0.3963948995141213 1.0 0.5801525067576891 61 Q9C0H2,Q8TDW0,P00846,P51790,P21796,P0CG08,Q9Y487,P45880,P23634,Q93050,Q9Y5K8,Q9Y6M7 12 +Glucose metabolism 0.462029615979107 0.7169799402008794 0.4733864742683367 1.0 0.6658200003936767 10 P31751 1 +Spermatogenesis 0.3666676801345715 0.5670585712775342 0.5706743885775678 1.0 0.7387272311345925 20 Q08J23,P46379,Q9P0K7,Q16181 4 +ER-Golgi transport 0.3144462040751575 0.5575455825030441 0.5771547245735673 1.0 0.7387272311345925 48 P24390,Q6NUQ1,P51572,O94979,O75396,O15027,Q12981,Q9P2W9,Q9Y282,Q92734,O43731 11 +Endocytosis 0.3504932402724876 0.5562326436283297 0.5780518262210228 1.0 0.7387272311345925 25 P50570,Q14C86,Q13432,Q8NC96,P02786 5 +Cholesterol metabolism 0.3177266063399105 0.3485677679504053 0.7274138292326724 1.0 0.8739068920642522 26 O15118,Q15392,Q16850,P04114,Q15800 5 +Cholesterol biosynthesis 0.3443743879248208 0.3126621142382148 0.7545373818588779 1.0 0.9002411521488681 15 Q15392,Q15800,Q16850 3 +Electron transport 0.282775250546655 0.2980050512175793 0.7656993083758459 1.0 0.9047231560481284 50 Q9P0J0,O95182,P51970,Q6DKK2,P00403,O75380,Q96CU9,P21912,O43678,P03886,O43676,O43169,O96000,Q9H1E5 14 +Nucleotide metabolism 0.3737949557939537 0.2940061525896874 0.7687532019599703 1.0 0.9047231560481284 8 Q969T7 1 +Differentiation 0.2781543132038455 0.2738862809842817 0.7841720148034295 1.0 0.9109100302994968 74 P46379,O94813,Q99426,Q96PU5,Q9Y4G8,Q08J23 6 +tRNA processing 0.3048623594479893 0.2734061721852592 0.784541008755058 1.0 0.9109100302994968 27 O75648,Q5VV42,O15091,Q9H974,Q08J23,Q99575 6 +DNA replication 0.2800138734328212 0.266469920781393 0.7898773219380892 1.0 0.910991844635263 49 P49321,Q9UFC0,P31350,Q9BRX5,Q96S55,Q13416,Q9BRT9,Q96RR1,P25205,P49005,P33991 11 +Sterol metabolism 0.2983883914923683 0.2378059387233037 0.8120316123566003 1.0 0.9236310018041464 28 P14324,O15118,Q15392,Q16850,P04114,Q15800 6 +Angiogenesis 0.349657708840234 0.2251180932283018 0.8218874058511276 1.0 0.9236310018041464 10 Q9H2J4,Q9BUP3 2 +Hydrogen ion transport 0.3009875681664556 0.2247268714654997 0.8221917588314367 1.0 0.9236310018041464 21 Q93050,Q9Y487,P00846 3 +Sterol biosynthesis 0.3140777526564872 0.2082055726935259 0.8350684575579757 1.0 0.932044149403418 17 Q15392,Q15800,Q16850,P14324 4 +Carbohydrate metabolism 0.2860674278696838 0.1526828711820715 0.878648369190588 1.0 0.942636085384962 21 P31751,Q15118 2 +Nonsense-mediated mRNA decay 0.3183198622541895 0.1484017460580905 0.8820257221755416 1.0 0.942636085384962 12 P52298,P11940 2 +Steroid metabolism 0.2819221666127471 0.1481082472111833 0.8822573408980612 1.0 0.942636085384962 29 P14324,O15118,Q15392,Q16850,P04114,Q15800 6 +Pyrimidine biosynthesis 0.3118523316062155 0.1475477578323902 0.8826996868922765 1.0 0.942636085384962 5 P27708,Q9NRF8,P17812,P30085 4 +Host-virus interaction 0.2433646400829489 0.0512542300273999 0.9591229392815146 1.0 1.0 240 Q9P0J0,P49721,Q9UBU9,Q9BUP3,P61221,Q07866,P12956,P61978,P21796,P14324,O15118,Q9Y3Z3,Q14108,P02786,Q8IZP0,P10321,Q8TAE8,O95793,Q9HCE1,Q99436,Q9BXS5,Q13573,O75525,Q7Z434,P62993,P28070,Q96PU5,O14734,P28074,Q96J02,P08670,P28072,Q14240,Q8IZA0,P20618,Q12981,Q96JB5,Q8WTV0,Q12824,O95639,P07948,O95071,Q15758,O43760,Q03518,O60502,Q71F23,Q7Z6E9,Q92538,Q9H3P7,Q05086,Q9ULX6,P51572,Q9Y2T2,P06493,O60506,Q86X55,P04439 58 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1147d49669f6f43acf159051ea51a4752934342d --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Anion exchange", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Copper transport", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "Digestion", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Ion transport", "Iron storage", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Menaquinone biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sexual differentiation", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT2", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALG13", "ALKBH5", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEX1", "API5", "APOB", "APOO", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARG2", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL8A", "ARL8B", "ARMC10", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATG3", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATRIP", "ATRX", "AUP1", "AURKA", "AURKB", "BABAM2", "BAG3", "BAG6", "BAHD1", "BAK1", "BANF1", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BICD2", "BIRC6", "BLM", "BMI1", "BMS1", "BNIP1", "BOP1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C2CD5", "CAAP1", "CACYBP", "CAD", "CAMK2G", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CARS2", "CBR4", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC59", "CCDC86", "CCDC93", "CCNB1", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC34", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CEBPZ", "CELF1", "CELF2", "CENPC", "CENPU", "CENPV", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CGGBP1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHST14", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLIC1", "CLPTM1", "CLPTM1L", "CLSPN", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "COG2", "COG5", "COG6", "COG7", "COL4A3BP", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS6", "COPZ1", "COQ8A", "COQ9", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCPS", "DCTN1", "DCTN3", "DCXR", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DECR1", "DECR2", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX15", "DHX16", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLST", "DMAP1", "DNAAF5", "DNAJB1", "DNAJB12", "DNAJC13", "DNAJC19", "DNAJC3", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPYSL2", "DSC1", "DSC3", "DSG2", "DST", "DTYMK", "DUS2", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECH1", "ECHS1", "ECI1", "ECSIT", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFL1", "EFTUD2", "EHD1", "EHHADH", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC4", "EMG1", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESCO2", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAM162A", "FAM208A", "FANCD2", "FANCI", "FAR1", "FAR2", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXK1", "FOXRED1", "FRYL", "FTL", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCFC2", "GCLC", "GCN1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GHITM", "GID8", "GINS3", "GINS4", "GLRX", "GM2A", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPI", "GPR89B", "GRB2", "GRSF1", "GRWD1", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HELLS", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD11", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILVBL", "IMP4", "IMPDH2", "INA", "INCENP", "ING5", "INTS13", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BP1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDLR", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LMAN1", "LMAN2", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPPRC", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L3", "LYAR", "LYN", "LYPLA1", "M6PR", "MACF1", "MAEA", "MAGT1", "MANF", "MAPK1", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MESD", "MFAP1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGEA5", "MGME1", "MGST2", "MIA3", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MKRN2", "MLEC", "MMS19", "MOCS1", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL41", "MRPL58", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MYBBP1A", "MYCBP", "MYDGF", "MYH10", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCEH1", "NCKAP1", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NME1", "NME6", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP10", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPM1", "NR2F2", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUBP1", "NUCKS1", "NUDC", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OGDH", "OGT", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "PA2G4", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCF11", "PCID2", "PCK2", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDK1", "PDK3", "PDS5A", "PDS5B", "PDZD8", "PECR", "PEDS1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGP", "PGS1", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHGDH", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIN1", "PISD", "PITPNB", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLIN3", "PLK1", "PLRG1", "PMAIP1", "PMF1", "PMVK", "PNN", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "POP1", "PPAT", "PPHLN1", "PPID", "PPIE", "PPIF", "PPIH", "PPIL3", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKCA", "PRKCB", "PRKDC", "PRKRA", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK7", "PTPMT1", "PTRH2", "PUF60", "PURA", "PUS1", "PWP1", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB35", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM14", "RBM15", "RBM17", "RBM22", "RBM23", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCOR1", "REEP3", "REEP4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN3", "RMND1", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPS1", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP14", "RPP30", "RPP38", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RPUSD3", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSF1", "RSL24D1", "RSRC1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDF4", "SDHA", "SDHB", "SDHC", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35B2", "SLC35F2", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMU1", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOAT1", "SON", "SPATA5", "SPC25", "SPECC1L", "SPEN", "SPNS1", "SPOP", "SPOUT1", "SPTLC1", "SPTLC2", "SRCAP", "SREK1", "SRFBP1", "SRM", "SRPK1", "SRPK2", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STK26", "STMN1", "STRAP", "STRBP", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNGR2", "SYS1", "TACO1", "TADA3", "TAF6L", "TAF9B", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBCB", "TBL1XR1", "TCEA1", "TCERG1", "TCF20", "TDRKH", "TECR", "TEFM", "TERF2", "TERF2IP", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", 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sha256:4ec317871ac821631ef2bd4874e137f7cc67c16ddbae11de4dfea76033bec5d4 +size 86707 diff --git a/protein_atlas_disease_involvement/df_merge.tsv b/protein_atlas_disease_involvement/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8fe3ea1a65364f72a6028babbf71e76d9f6e575a --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Neuronal ceroid lipofuscinosis 3 5 2.5823450150667338 0.0098131427319423 2.1941747572815533 3.616504854368932 0.8145003765175237 0.1716854616439567 0.950812145720796 0.8293870806734848 1.6764073513361384 0.2241811956153294 0.0506000729453915 0.0561990347849709 0.1094892401774078 0.00262770885776 0.0019443402252438 +Diabetes mellitus 2 9 2.166213030093338 0.0302949118867492 3.1966019417475726 10.315533980582524 0.6190680538080506 0.4730085508812801 1.8480344075927575 1.973723369210009 0.8597438282474712 0.3113207504672028 0.1554752784430136 0.1715759324473242 0.3143397790261298 0.0678108138951911 0.2904552114252967 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..22c5ec0234f8eaf185ba5c256e78d33a5809aca7 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 114, + "title": "Average number of proteins per term", + "value": 21.37719298245614 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d3e9dbd367f03748e3aa629713c428a78fd831c0 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..217f07b94d5fbaceed10ed455c602a5daf854187 --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,30 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Leber hereditary optic neuropathy 0.9773536072468468 3.8923770240611018 9.926682019156809e-05 0.0112531830887553 0.0028291043754597 2 P03886 1 +Ehlers-Danlos syndrome 0.9045627912921104 3.287966729291905 0.0010091376450471 0.1087227895558293 0.009058583736026 3 Q9NWM8 1 +Cone-rod dystrophy 0.8204464574571382 3.176851549246305 0.0014888322393757 0.156211449415658 0.0121233482349171 2 Q13432 1 +Dystroglycanopathy 0.7939178259463007 3.049053330618449 0.0022956372546973 0.2304916655144872 0.0153942733550295 2 O60762 1 +Premature ovarian failure 0.7379488838563557 2.772283002507914 0.0055664618864923 0.4707791297455047 0.0285230773987653 2 Q06787 1 +Neuronal ceroid lipofuscinosis 0.8493127998325417 2.5823450150667338 0.0098131427319423 0.6750953161438473 0.0414332693126454 5 Q8NHS3,O75503,O14773 3 +Diabetes mellitus 0.7652552078084736 2.166213030093338 0.0302949118867492 0.970013700071982 0.0885543578228055 9 P31751,P03886 2 +Nemaline myopathy 0.5211905532190342 1.6020532160008991 0.1091438422081751 0.9999981030108974 0.2073733001955328 2 Q9Y281 1 +Fanconi anemia 0.5978203252525721 1.5878241091477512 0.1123261181554819 0.9999987384851692 0.2099209421266384 4 Q9BXW9,P38398 2 +FDA approved drug targets 0.3539255413901147 1.4725749329473583 0.1408656880849372 0.9999999695938584 0.2388427980488535 111 P48735,P49721,Q15758,Q15118,Q13423,P50416,Q99720,P20618,P02786,P23786,P05771,P03886,P23634,Q16850,P38435,P28074 16 +Mucopolysaccharidosis 0.5743275904193756 1.468166435364861 0.1420590190904742 0.999999974049538 0.2388427980488535 4 P54802 1 +Progressive external ophthalmoplegia 0.5855448827596164 1.3582544816934192 0.1743829483037671 0.9999999996743384 0.2839950872375635 5 Q96RR1 1 +Neurodegeneration 0.3273208317741733 1.3198595988682755 0.1868818986300129 0.9999999999427844 0.2987510249845084 134 Q13614,Q99720,Q96B26,P03886,Q14108,P50897,Q9NQT5,O14653,Q8NHS3,O14773,Q8N0X7,O95831,Q9BRK0,P54802,P50570,O43464,O75503,P49902,Q9NSD9,Q96RR1,Q96D71,Q03252,Q96RL7,Q8IY17,Q71SY5,Q10713,P07196 27 +Leigh syndrome 0.5766104480237952 1.2943258240205653 0.195552900102748 0.9999999999831456 0.3053839809823737 10 Q7KZN9,P00846 2 +Osteogenesis imperfecta 0.5886112430196515 1.279443665128942 0.2007408656958749 0.999999999991939 0.3062666607904274 8 Q32P28,Q96AY3 2 +Primary mitochondrial disease 0.3410057634688075 1.1851195617527823 0.2359701777367175 0.9999999999999528 0.34879307026241 104 Q9P0J0,Q7KZN9,P00846,O43819,Q70HW3,Q6DKK2,Q9BQP7,Q96CU9,Q5XKP0,Q9Y584,Q9Y375,P03886,Q9BQT8,Q96RR1,P13073,O95831 16 +Hereditary nonpolyposis colorectal cancer 0.4483985765124588 1.178373116952549 0.2386478901795437 0.9999999999999684 0.34879307026241 2 P43246 1 +Retinitis pigmentosa 0.4500208409002427 0.8795876819575473 0.3790827142799613 1.0 0.5144693979513761 15 Q8IY17,P00846 2 +Epilepsy 0.3174562333922054 0.7401627392119744 0.4592012536097416 1.0 0.6155860062603216 63 Q96RL7,O75787,Q92643,O43464,Q96F07,O75503,P57740,P03886,Q9Y4G8,Q14108,Q8NC96,O14773,Q03252,O14653 14 +Kartagener syndrome 0.3697832416693613 0.7228218840569954 0.4697893205670875 1.0 0.6155860062603216 2 Q9NVR5 1 +Primary ciliary dyskinesia 0.3697832416693613 0.7228218840569954 0.4697893205670875 1.0 0.6155860062603216 2 Q9NVR5 1 +Lissencephaly 0.4515086410242821 0.642128982275016 0.5207894393593415 1.0 0.6560982308869446 9 Q9BSJ2 1 +Hereditary spastic paraplegia 0.35120913093846 0.4416660662054099 0.6587308686827273 1.0 0.7822429065607388 19 Q9BRK0,Q8IY17,O75298,Q92734,P49902,Q8N0X7 6 +Charcot-Marie-Tooth disease 0.3320239510341949 0.4300550041362288 0.6671556301592569 1.0 0.7840798127644876 22 Q13614,P54802,Q71SY5,P50570,O95831 5 +Neuropathy 0.2927093914514657 0.3432148524898669 0.7314368318977271 1.0 0.8255821666964445 45 Q13614,P54802,Q71SY5,P50570,P00846,Q96RR1,O95831 7 +Dwarfism 0.284545845934879 0.3042250726906693 0.7609564243249443 1.0 0.8422236152722684 49 Q96HY6,Q8IY17,Q32P28,O75718,Q99575,Q9NUQ7,O95831 7 +Cardiomyopathy 0.3006086174028503 0.2472646824359824 0.8047033896016305 1.0 0.8736779658531988 23 P49748,O43819,P00846 3 +Proto-oncogene 0.2638173424886471 0.121933242556446 0.9029518882949532 1.0 0.9479077789615332 44 P07948,Q16204,P55196,P31751,P46108,Q92804,Q92733,O96028,Q92734,Q03164 10 +Hypotrichosis 0.3007281174542359 0.0691085324985019 0.9449032293172176 1.0 0.9792633467469348 7 P48449 1 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0a81973f8a63fc0ca8f21c937f2f7376fec52879 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atherosclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital dyserythropoietic anemia", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Corneal dystrophy", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AARS", "AARS2", "ABAT", "ABCB1", "ABCB7", "ABCC1", "ABCD4", "ABHD12", "ABI1", "ACAA1", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADAR", "ADD3", "ADK", "ADNP", "ADSL", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AKAP12", "AKR1B1", "AKT2", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANO10", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA7", "AP1B1", "AP1S2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APEX1", "APOB", "APRT", "ARCN1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL2", "ARL3", "ARL6IP1", "ASAH1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATIC", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP7A", "ATP7B", "ATRX", "ATXN10", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BAG3", "BANF1", "BARD1", "BAX", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCKDHA", "BCKDHB", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BMI1", "BMS1", "BPTF", "BRCA1", "BRD3", "BRD4", "BRI3BP", "BUB1B", "BUD23", "C19orf70", "C1QBP", "C3orf58", "CAD", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBX2", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC6", "CCNB1", "CCT5", "CDC16", "CDC27", "CDC34", "CDC37", "CDC42", "CDC73", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDKAL1", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHEK1", "CHP1", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COL4A3BP", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COQ9", "COX15", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRK", "CRTAP", "CSDE1", "CSE1L", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DBN1", "DBT", "DCPS", "DCTN1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIAPH1", "DIS3", "DKC1", "DLD", "DLST", "DNAAF2", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC13", "DNAJC19", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DSC3", "DSG2", "DSP", "DST", "DYNC1H1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EHHADH", "EHMT1", "EI24", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF5A", "ELAC2", "ELL", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "ENO1", "EPB41", "EPB41L3", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ESCO2", "ETFA", "ETFB", "ETFDH", "EXOC6B", "EXOC8", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EZR", "FADS2", "FAF1", "FAM120A", "FAM3C", "FANCD2", "FANCI", "FAR1", "FARS2", "FARSB", "FASN", "FASTKD2", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GALK1", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GCDH", "GCLC", "GDAP1", "GEMIN4", "GFM1", "GFM2", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLS", "GLUD1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNPAT", "GNS", "GOLGA5", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPI", "GPT2", "GRB2", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2I", "GTPBP3", "GUF1", "GYG1", "GYS1", "H4C1*", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HK2", "HLA-A", "HMGA1", "HMGB3", "HMGCL", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOXD11", "HPRT1", "HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IFT81", "IGBP1", "IGF2R", "ILF3", "ILK", "IMPAD1", "IMPDH2", "INTS1", "INTS8", "IPO7", "IRF2BPL", "IRS4", "ITGAV", "ITGB1", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KIDINS220", "KIF11", "KIF1A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KMT2A", "KMT2B", "KTN1", "L2HGDH", "LAMB1", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETMD1", "LGALS3BP", "LGMN", "LIN9", "LIPA", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPPRC", "LSS", "LTA4H", "LYN", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN2B1", "MAP4", "MAPK1", "MARS", "MARS2", "MATR3", "MBD1", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED12", "MED17", "MED23", "MED25", "MESD", "MFN2", "MFSD8", "MGME1", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MMAB", "MOCS1", "MOGS", "MORC2", "MPDU1", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MYH10", "MYH9", "MYO6", "NAA15", "NAGLU", "NAMPT", "NANS", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG2", "NCAPH", "NCKIPSD", "NCOR1", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEFL", "NEK9", "NEPRO", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NISCH", "NME1", "NNT", "NONO", "NOP10", "NOP56", "NPC1", "NPC2", "NPM1", "NR2F2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSMCE2", "NSMCE3", "NSUN2", "NSUN3", "NSUN5", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OCLN", "OGDH", "OGT", "OPA1", "OPA3", "ORC6", "OXCT1", "P3H1", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCNA", "PDCD4", "PDHA1", "PDHB", "PDK1", "PDK3", "PEPD", "PEX11B", "PEX14", "PEX19", "PEX3", "PFKM", "PFN1", "PGK1", "PGM1", "PHB", "PHF6", "PHGDH", "PHIP", "PI4KA", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIN1", "PINX1", "PISD", "PKM", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNN", "PNP", "PNPLA4", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP2R1A", "PPP2R5D", "PPP5C", "PPP6C", "PPT1", "PQBP1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PTDSS1", "PTRH2", "PUF60", "PURA", "PUS1", "PYCR1", "PYCR2", "PYGL", "QARS", "QKI", "QRSL1", "RAB10", "RAB11B", "RAB18", "RAB3GAP2", "RAB7A", "RAB8A", "RABL3", "RAC1", "RAD21", "RAD23B", "RAD51C", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM15", "RBM28", "RBM6", "RBMX", "RBPJ", "RDH11", "RDX", "REEP2", "REPS1", "RFC1", "RFC2", "RFT1", "RHOA", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNASET2", "RNPC3", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", 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"SORD", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPOP", "SPR", "SPTAN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRP54", "SRP72", "SRSF3", "SSB", "SSR4", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STMN1", "STRAP", "STRN", "STT3A", "STT3B", "STUB1", "STX5", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D4", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCEA1", "TCF20", "TCOF1", "TECR", "TELO2", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIMM17A", "TIMM22", "TIMM50", "TIMMDC1", "TK1", "TKT", "TMCO1", "TMEM126B", "TMEM165", "TMEM199", "TMEM230", "TMEM43", "TMEM70", "TMF1", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TPX2", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSG101", "TTC19", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUFM", "TWNK", "TXLNA", "TXNDC15", "TXNRD1", "TYMS", "U2AF1", "UBA1", "UBAP1", "UBE2N", "UBE3A", "UBIAD1", "UBQLN4", "UBR5", "UBTF", "UFC1", "UFSP2", "UMPS", "UNC119", "UPF3B", "UQCRB", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP9X", "UTP4", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VKORC1L1", "VPS13A", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WBP2", "WDR1", "WDR26", "WDR36", "WDR5", "WFS1", "WIPI2", "XPNPEP3", "XPO1", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZC3H14", "ZCCHC8", "ZEB2", "ZMPSTE24", "ZMYM2", "ZNF148", "ZNF644"], "leading_proteins": ["ACADVL", "AFDN", "AIFM1", "AKT2", "ATP2B4", "ATP6", "ATP6AP2", "BRCA1", "C19orf70", "CCDC6", "CFL2", "CLN5", "COX15", "COX4I1", "CPT1A", "CPT2", "CRK", "CRTAP", "CYFIP2", "CYP51A1", "DDRGK1", "DNAAF2", "DNM2", "DPM1", "EXOSC3", "EXOSC8", "FANCD2", "FARSB", "FKBP10", "FKBP14", "FMR1", "FOXRED1", 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sha256:e75428e98c31403633a6347c245de10efbdbffaaa0f6fa8cd36adab5db980c38 +size 148258 diff --git a/protein_atlas_molecular_function/consensus.joblib b/protein_atlas_molecular_function/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..fa97cedf198cf530ce9af235dd6b5521121b8d09 --- /dev/null +++ b/protein_atlas_molecular_function/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7e64152a8d2b5bab2cc679ee46b6f589aefe95a4b96b6bab27595641edbba842 +size 84014 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..971d85c80706c6f383701242c31226fcb512f556 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Protease 27 74 3.067020250443766 0.002162042095378 20.788834951456312 82.44417475728156 1.1215350835872162 0.3507517256058336 6.07090559629836 8.079357013764625 1.4678877461728397 0.3691345771929886 0.0004252659380112 0.0007670318408205 6.922830596561845e-05 0.0001467010678635 5.649004950939052e-06 +Receptor 14 43 2.8954504026729526 0.0037861485502828 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 0.6653399447083752 0.7045733708560526 0.4328346363727663 0.1535245661700581 0.096683593880526 +Metalloprotease 12 25 2.833017114271858 0.0046110917177504 8.160194174757281 26.429611650485437 1.390302281711237 0.2661274848815638 3.192614043118206 1.543038499308978 1.1108461579919544 0.309446154241223 0.0019607751615915 0.0026733926607684 1.827159812714955e-05 7.125032306985868e-05 2.8137949230689167e-06 +Carboxypeptidase 3 6 2.3761746933508205 0.0174931786512229 3.1359223300970873 6.150485436893204 0.9957728306848488 0.1212034427500092 1.2071674596015187 0.4479454254223922 1.8250051834990677 0.2074401112551974 0.062853835992264 0.0697581245313758 0.0088504827764808 0.000371706641515 0.0047772438954047 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..290e014bf6cef814995b76bd05ce2a86a7073a54 --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 97, + "title": "Average number of proteins per term", + "value": 37.36082474226804 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f3183499c4d7a1566ad818097c46415bbfcbb9b1 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b3fc799d2ccbe492043f44057f41b3ae475ae785 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,29 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protease 0.5327453558733473 3.067020250443766 0.002162042095378 0.189371268120066 0.0125683933165914 74 P42785,Q5JRX3,Q4J6C6,Q9NZ08,P55786,P42892,Q96K76,Q7Z2K6,P17655,Q99436,P48147,Q96TA2,Q5TDH0,O14773,P28074,Q9H3G5,P28072,O43464,Q9UIQ6,P52888,O75976,Q9BYT8,Q92643,Q9HB40,P09960,Q9NUQ7,O43847 27 +Threonine protease 0.8540453074433454 3.061445876609308 0.0022027081070314 0.1925695444709419 0.0125683933165914 3 P28074,Q99436 2 +Receptor 0.590167875301598 2.8954504026729526 0.0037861485502828 0.3078505738281994 0.0172462963954941 43 P30825,Q15758,Q9NS69,Q99720,P24390,O15173,P11717,O15118,Q14108,Q8WTV0,O43731,P02786,Q5KU26,Q9UBG0 14 +Metalloprotease 0.6834651954401009 2.833017114271858 0.0046110917177504 0.3612935326955713 0.0186364956925746 25 Q7Z2K6,Q5JRX3,Q96TA2,Q9UIQ6,P09960,P52888,Q9NZ08,P55786,O75976,Q9BYT8,P42892,O43847 12 +Chloride channel 0.8114418387307165 2.6156480160022983 0.0089058311658813 0.5800985912193756 0.0345546249236198 4 Q9C0H2 1 +Carboxypeptidase 0.8461111265541198 2.3761746933508205 0.0174931786512229 0.8194694501306454 0.056561277638954 6 P42785,O75976,Q9HB40 3 +Voltage-gated channel 0.7374485861414919 2.273017084738988 0.0230251504014384 0.8956029505249917 0.0720464383528881 4 P0CG08 1 +Ion channel 0.6716556587031076 1.770337052677419 0.0766710090893252 0.9995639083507838 0.188621912848316 10 Q9C0H2,Q8TDW0,P0CG08 3 +Acyltransferase 0.4728694158896164 1.7410698030823184 0.0816713437075182 0.9997424750854834 0.188621912848316 38 Q9BWD1,Q8NCC3,P23786,Q9HCL2,Q86UY6 5 +Aminopeptidase 0.6577790871377354 1.701856972500335 0.0887821833704451 0.9998788415625812 0.191888302279099 10 Q9UIQ6,P55786 2 +Muscle protein 0.6929023538360978 1.7005881737566644 0.0890203464181387 0.9998818750345446 0.191888302279099 6 P67936,Q03001,P14649 3 +Porin 0.6125112034333609 1.66211017956282 0.0964906848910502 0.9999468546168094 0.2034694877050408 4 P21796 1 +Transducer 0.6422224235517062 1.5014889075529287 0.1332291535874727 0.999999052200084 0.2749622957018055 7 P02786,P04899,Q14344 3 +Heparin-binding 0.6327541342824982 1.4230830817386024 0.1547120721589094 0.9999999169283846 0.3001414199882844 6 O94813 1 +Hydrolase 0.2896894658531799 1.308776804736436 0.190609966230729 0.99999999876601 0.3530450735450847 360 Q13614,P42785,Q9H6V9,Q86YN1,Q9BQP7,P12956,Q99956,Q8NHP8,Q4J6C6,Q9UQ84,Q15165,P42694,Q9NZ08,P55786,Q9H773,Q9NPH0,P50897,P42892,Q96K76,Q7Z2K6,Q15102,O60476,Q99436,Q8NCC3,Q96S55,Q9UNW1,O14773,P25205,Q9UMR5,Q99575,P28074,Q9H3G5,P50570,Q9UIQ6,Q969T7,P52888,Q96RR1,O75976,Q9BYT8,Q8IY17,Q9HB40,O60502,Q9NUQ7,Q6PIU2,Q8NHH9,P07099 46 +Guanine-nucleotide releasing factor 0.5380715693255762 1.2758551307316697 0.2020067347276004 0.999999999688165 0.3628639494180971 13 Q9Y4F1,A4D1U4,Q14C86,Q9Y4G8,P80303 5 +Host cell receptor for virus entry 0.4854022748515672 1.22465509198154 0.2207052010993204 0.999999999968734 0.3822929376184658 18 O15118,Q15758,Q14108,Q8WTV0 4 +Translocase 0.4383194221123967 1.2010346594582202 0.2297377569910623 0.9999999999899088 0.3909572355812815 27 Q9HD20,P03886,P23634,P08183 4 +Tyrosine-protein kinase 0.5663963716679683 1.1124184481227049 0.2659582762872134 0.9999999999999056 0.4447922896527536 6 P07948,P19525,Q15375 3 +Serine protease 0.53556803218447 1.0857273898727864 0.2775996190277205 0.99999999999998 0.4563925939947271 10 O43464,Q4J6C6,O14773 3 +GTPase activation 0.4015044402699505 0.6674137553979701 0.5045078819729809 1.0 0.7092357181359297 17 Q66K14,Q9Y4G8 2 +Glycosidase 0.3716587122521278 0.560738246197434 0.5749759903048199 1.0 0.7434894451092514 19 O60476 1 +Oxidoreductase 0.2751202012460812 0.4537225135264919 0.650028560660763 1.0 0.7689362241962684 174 O15254,Q9UBQ7,Q9BUP3,Q32P28,Q8NB78,P30519,Q9BTZ2,Q8N0U8,P30837,Q8N4Q0,P49748,Q9UHQ9,Q53GQ0,Q8NBX0,Q15392,P13073,O95831,P13674,Q9UHG3,P09601,Q96CU9,Q6ZRP7,Q5VT66,P48735,Q8NBM8,Q9H6W3,Q16850,Q15800,P53004 29 +Initiation factor 0.3286837485374534 0.4393277141088407 0.6604240956522256 1.0 0.7718209310634444 30 P55010,P23588 2 +Calmodulin-binding 0.3283693478129901 0.4243199265081944 0.6713325088715321 1.0 0.7752292066730787 28 Q13576,Q13555,P49006,Q9UEY8,P23634,P35580,P35611,O43815 8 +Developmental protein 0.2899259181236045 0.4055141182200235 0.6850996428293636 1.0 0.7818195924052738 72 Q9UNS1,Q9Y4F1,O94813,Q9BUP3,Q13045,Q8NB78,Q99426,P31751,Q13555,Q92520,Q9Y4G8,Q9NQZ2,Q92974 13 +Rotamase 0.300672303214438 0.2009734773606039 0.8407193129329469 1.0 0.8961513555439105 20 O95302,Q9NWM8 2 +Dioxygenase 0.3046602709447741 0.1447529324964839 0.8849059451403138 1.0 0.9229664158990368 15 Q32P28,Q9H6W3 2 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8b8d5c56d2621f2b71f0899e3b7fa68e83f17308 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA replication inhibitor", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgG-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCC1", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ANLN", "ANO6", "ANP32B", "ANXA1", "ANXA2", "APBB1", "APEH", "APEX1", "APLP2", "APOB", "APRT", "AQR", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL8B", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7A", "ATP7B", "ATRX", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BANF1", "BAP18", "BARD1", "BAZ1B", "BCAT2", "BCKDHA", "BCKDHB", "BCLAF1", "BCOR", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "CAD", "CALR", "CAMK2G", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX2", "CBX3", "CBX8", "CCAR1", "CCAR2", "CCDC47", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC34", "CDC37", "CDC42", "CDC5L", "CDCA7L", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPU", "CEPT1", "CERS1", "CERS2", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT9", "CNP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPS5", "COQ8A", "CORO1C", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRYZ", "CS", "CSDE1", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CUL5", "CXADR", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCPS", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPRS", "ERAL1", "ERAP1", "ERCC3", "ERCC6L", "ERMP1", "ERO1A", "ERO1B", "ERP44", "ESCO2", "ESD", "ETFDH", "EXD2", "EXO1", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "F11R", "FADS2", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLYWCH1", "FMR1", "FN3KRP", "FOXK1", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDE1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GGCT", "GGCX", "GGH", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPI", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPAD1", "IMPDH2", "INA", "ING5", "INTS11", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "KARS", "KAT7", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIAA1147", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KRR1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPAP1", "LRPPRC", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L3", "LYAR", "LYN", "LYPLA1", "M6PR", "MACF1", "MAEA", "MAGED2", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAPK1", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MATR3", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFN1", "MFN2", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOCS1", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MYBBP1A", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCAM1", "NCBP2", "NCBP3", "NCEH1", "NCL", "NCOA5", "NCOR1", "ND1", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NEPRO", "NES", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NKRF", "NKTR", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUCB1", "NUCB2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NUSAP1", "NXF1", "NXN", "OAT", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC6", "OTUB1", "OXCT1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PEBP1", "PECR", "PEDS1", "PELO", "PELP1", "PEPD", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB2", "PHC2", "PHF2", "PHF5A", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PIAS1", "PIGG", "PIGK", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP5C", "PPP6C", "PPT1", "PPT2", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKCA", "PRKCB", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRSS3", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "RAB10", "RAB11B", "RAB18", "RAB1A", "RAB1B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAI1", "RALA", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC3", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOX1", "RIPK1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPEP", "RNPS1", "ROMO1", "RP2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP14", "RPP30", "RPP38", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RREB1", "RRM1", "RRM2", "RRP1B", "RRP7A", "RRP8", "RRP9", "RSBN1", "RSBN1L", "RSF1", "RTCB", "RTF1", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARNP", "SARS", "SARS2", "SART3", "SC5D", "SCAF1", "SCAF8", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SENP3", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A2", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMYD3", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAT1", "STAT3", "STAU1", "STAU2", "STK26", "STMN1", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRKH", "TECR", "TERF2", "TERF2IP", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TLE3", "TM7SF2", "TMCO1", "TMEM109", "TMEM126B", "TMF1", "TMOD1", "TMOD3", "TMPPE", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TST", "TTF1", "TTYH3", "TUFM", "TWNK", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBIAD1", "UBN1", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF3B", "UROD", "USP10", "USP14", "USP19", "USP36", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP3", "UTRN", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VRK1", "VRK2", "WARS", "WARS2", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR5", "WRNIP1", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "ZADH2", "ZC3H13", "ZC3H14", "ZC3H8", "ZC3HAV1", "ZCCHC17", "ZCCHC3", "ZDHHC20", "ZEB2", "ZFR", "ZMPSTE24", "ZNF148", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZRANB2"], "leading_proteins": ["ABCB1", "ACADVL", "ACAT2", "ACOX3", "ACP6", "ADD1", "ADD3", "AIFM1", "AKT2", "ALDH1B1", "ARHGEF2", "ATL2", "ATP13A1", "ATP2B4", "BLVRA", "CAMK2G", "CAPN2", "COLEC12", "COX4I1", "CPD", "CPT2", "CPVL", "CYB5R1", "CYP51A1", "DCTPP1", "DDI2", "DHCR24", "DHRS4", "DNM2", "DOLPP1", "DST", "DUSP9", "ECE1", "EIF2AK2", "EIF4B", "EIF5", "EPHA7", "EPHX1", "ERAP1", "ERMP1", "EXO1", "FAM3C", "FARP1", "FKBP14", "FKBP9", "FLII", "FOXRED1", "GAPVD1", "GNA13", "GNAI2", "GPAM", "GPR89B", "GRHPR", "HELZ", "HMOX1", "HMOX2", "HSD17B12", "HTATIP2", "HTRA2", "IDH2", "IGF2R", "IQGAP2", "KDELR1", "KDELR3", "KDM1B", "KIAA1147", "LDAH", "LNPEP", "LRRC8C", "LTA4H", "LYN", "MAN1A2", "MARC1", "MARCKSL1", "MCM3", "MGEA5", "MGME1", "MINPP1", "MRC2", "MSMO1", "MTMR2", "MYH10", "MYL6B", "NAA40", "NCEH1", "ND1", "NLN", "NPC1", "NPEPPS", "NRDC", "NT5C3B", "NUCB2", "P3H1", "P4HA1", "PAFAH1B3", "PCYOX1", "PCYOX1L", "PGRMC2", "PIGK", "PITRM1", "PLA2G15", "PLBD2", "PNPLA6", "PON2", "POP1", "PPT1", "PPT2", "PRCP", "PREP", "PREPL", "PSMB5", "PSMB6", "PSMB7", "QSOX2", "RAPGEF2", "RIOX1", "SCARB1", "SCARB2", "SCCPDH", "SCPEP1", "SIGMAR1", "SLC1A5", "SLC7A1", "SLIT2", "STRN", "TBC1D9B", "TBCB", "TFRC", "THOP1", "TIMELESS", "TOMM22", "TPM4", "TPP1", "TTYH3", "TWNK", "UFSP2", "USP47", "UTP3", "VDAC1", "VKORC1L1", "WRNIP1", "XRCC6", "YME1L1", "ZADH2"]} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/idx2term.json b/protein_atlas_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..3b4a91a6451b09fdb7f3c18823315586d5adcbb5 --- /dev/null +++ b/protein_atlas_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Predicted membrane proteins", "1": "Predicted secreted proteins", "2": "Transporters"} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/plot_0.png b/protein_atlas_protein_class/advanced/plot_0.png new file mode 100644 index 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0000000000000000000000000000000000000000..aee22e6e47aa04445b3bb3c42bb45e57107a05e3 --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fc1e7617842baecfc13f29eddbddfbca9123db4326b921cb4152cce7ba160af9 +size 93061 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b60ad92121cc6c643beb307528164d697a0152f8 --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 172 624 5.161213300128502 2.453544268114593e-07 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 2.3651832633060523e-06 3.538686468070131e-07 8.314904430757826e-09 7.927572223242637e-10 1.923119499816169e-11 +Predicted secreted proteins 14 55 2.5177241430665105 0.01181157889545 15.29368932038835 51.737864077669904 1.393291060716792 0.256881456821794 5.463351773637434 6.9884942404294375 1.5049506819867255 0.3173597508227758 0.692400565153258 0.7310572648855516 0.4805906600463954 0.1185127466126223 0.2277072114083925 +Transporters 71 390 2.235147240845168 0.0254076838399641 108.9004854368932 367.3009708737864 1.469396346451591 0.4764419032567517 40.40141182476491 35.10022679965902 2.352674986871393 0.4490473364946538 0.0004330292154395 0.0003394393223519 0.0004827346345 0.0002528750693301 3.634004033376979e-05 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d79c837a885dfdec6c3f2bbb430a959eb00a996f --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 21, + "title": "Average number of proteins per term", + "value": 475.0952380952381 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1ca4ae39bc0e8e4b983eb7441b7731613e7a8dd9 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8dd750037ea46c449dc52fb49c90878d96fef1b6 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,9 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.4292730956631894 5.161213300128502 2.453544268114593e-07 5.1524303213343885e-06 5.152442963061644e-06 624 Q96PV6,Q96PC5,Q567V2,Q8IXU6,Q9H6V9,O60830,Q70HW3,Q99720,Q8NBM4,Q5VW38,P30519,Q6NUM9,P29372,Q99595,O60831,O75396,O43772,P03886,P42892,Q5BJF2,Q92896,Q7Z2K6,O60637,Q8NHS3,Q13641,O60476,P41440,Q9H061,Q16625,Q9NR77,Q96CP7,Q8NCC3,Q8NBX0,Q9NPR9,O95831,Q5KU26,Q15047,Q9C0H2,Q9BRK0,P00846,O95563,Q9UI14,Q9UIQ6,P09601,Q8IZA0,Q9Y584,O75976,Q8WTV0,Q8TBP6,P08183,Q86VD7,O00461,P30825,Q8IY17,Q7KZN9,O43760,Q9Y619,P51790,Q9H6K4,O60725,Q05086,Q96H78,Q16850,O43731,Q9HD20,O94813,Q9UDX5,Q86YN1,P0CG08,O15118,Q9HCL2,P09669,O14653,Q5BJH7,Q96HH6,P24390,Q53GQ0,O15173,Q13555,Q8WWI1,Q9Y487,P23634,Q8NCH0,Q9NX40,Q9Y6M7,Q5VV42,Q92575,Q9P260,Q92804,P38435,Q9NQX7,Q15758,Q13423,O43819,P50416,Q9P0S9,Q9Y282,Q6PIU2,Q5SWX8,Q93050,Q8NHH9,Q96G23,Q00765,Q9P0J0,Q9NS69,P42694,P11717,Q9HC07,Q14108,P02786,Q13505,Q8TCG1,Q15392,P46783,P43307,P13073,Q96M27,Q96IX5,Q86XL3,Q08722,O43464,Q9GZM5,Q6ZRP7,Q12981,Q06481,P27105,Q9UBG0,O60925,O15126,Q15631,Q03518,P51572,P20645,O15400,Q9NPA0,Q15800,Q8TDW0,Q9BUP3,Q6P4A7,Q8N0U8,Q3SXM5,Q9Y3D6,P10321,Q96TA2,Q8IXB1,O96011,O95470,O43169,A1L0T0,Q13190,Q8WVI0,Q8WXH0,Q4KMQ2,Q3B7T1,O75381,O94901,P51571,Q15375,Q9P2W9,Q99808,Q99567,Q92643,P33527,O75844,O75787,O75448,Q96A26,P31350,P51003,O60499,O94919,P04439 172 +Predicted secreted proteins 0.4986582634845407 2.5177241430665105 0.01181157889545 0.220825057955471 0.0496086313608901 55 Q8WUJ1,Q9H6E4,O94813,Q9HB40,O75718,Q15165,Q92520,Q9UMX5,Q9UM22,Q9NZ08,Q8NBM8,P04114,P02786,P80303 14 +Transporters 0.3310553935779137 2.235147240845168 0.0254076838399641 0.4175178202395 0.0794929036962126 390 Q9HD20,Q8TDW0,Q8IXU6,Q70HW3,Q99720,Q5VW38,P11717,O15118,Q6P4A7,O43772,Q9HC07,Q14108,P02786,Q5BJF2,O60637,Q8NHS3,P41440,Q9H061,Q16625,Q9NR77,P60602,P24390,Q13555,P45880,O43681,P23634,P13073,Q13190,P80723,Q9Y6M7,Q9C0H2,P50570,Q08722,O95563,Q9UI14,Q4KMQ2,O75381,O94901,Q9GZM5,P27105,Q99808,Q96EE3,Q8WTV0,Q99567,Q9BRK5,Q8TBP6,P14635,P05771,P08183,Q86VD7,Q96RL7,O15126,P30825,P33527,Q15758,O75844,O75787,P50416,Q03518,Q9H814,P51572,Q9Y619,P20645,Q96P70,P57740,P52298,Q96H78,Q9BQT8,Q9NPA0,Q93050,Q8NHH9 71 +FDA approved drug targets 0.3539255413901147 1.4725749329473583 0.1408656880849372 0.9587634477751386 0.2958179449783683 111 P48735,P49721,Q15758,Q15118,Q13423,P50416,Q99720,P20618,P02786,P23786,P05771,P03886,P23634,Q16850,P38435,P28074 16 +CD markers 0.3930142198541245 0.6528217222286855 0.5138712179359088 0.999999735894142 0.7194197051102723 18 P02786,P11717,P08183,Q08722 4 +Candidate cardiovascular disease genes 0.3578415898574477 0.2551927960628059 0.7985741948265723 0.9999999999999976 1.0 10 Q15165 1 +Metabolic proteins 0.2403636144010547 0.1777886316894126 0.8588889757108473 1.0 1.0 874 Q9BWD1,Q70HW3,P30519,P23786,O43772,P55786,P03886,Q9H773,Q9NPH0,P30837,Q8N4Q0,Q96K76,Q13011,O60476,P41440,Q8NCC3,Q8NBX0,Q96PU5,Q9UNW1,Q9UMR5,Q15047,Q9UHG3,P22830,P00846,O95563,P09601,Q969T7,P52888,Q86UY6,Q9NSD9,Q8WTV0,Q8TBX8,P49005,P08183,Q86VD7,P30825,P48735,Q8IY17,P31751,O60502,Q9Y619,O60725,Q05086,Q9BQT8,Q16850,O95302,P07099,P55263,Q13614,Q13126,Q86YN1,Q99426,Q99956,Q9NWM8,P61457,Q15165,O15118,Q9BZK7,Q9HCL2,Q96AY3,Q03164,P09669,P49366,P49748,Q15118,Q53GQ0,Q13555,Q9Y487,Q9BRR6,P23634,O14773,Q8NCH0,Q9Y6M7,P50570,Q9Y5P4,P48449,Q9BYT8,Q96EE3,Q9H974,P05771,Q9NXR7,Q15758,Q13423,P50416,Q10713,Q93050,Q96G23,Q9NZL9,Q9P0J0,Q9BTZ2,P50897,P04114,O96000,P02786,Q16763,Q9H0E3 96 +RAS pathway related proteins 0.2876907674777587 0.1262451503489318 0.8995378724357579 1.0 1.0 19 O00459,P31751,P05771,P55196 4 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1e005fbe751faf121b514c4421bc5fb97ecbf406 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Nuclear receptors", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf35", "C1orf52", "C2CD5", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf33", "CAAP1", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC59", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPI", "CENPL", "CENPP", "CENPQ", "CENPU", "CENPV", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM114A2", "FAM120A", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM207A", "FAM208A", "FAM208B", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMC1", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH8", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LETMD1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM12", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "M6PR", "MACF1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP", "MYDGF", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NENF", "NEPRO", "NES", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "ROMO1", "RP2", "RPA1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RSRC1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35B2", "SLC35F2", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPNS1", "SPOP", "SPOUT1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THEM6", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THYN1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF3", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED8", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM19", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM223", "TMEM230", "TMEM245", "TMEM33", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBFD1", "UBIAD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "UROD", "USMG5", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS16", "VPS25", "VPS26A", 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--- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Golgi apparatus 41 174 3.550926981904579 0.0003838769015258 46.45873786407767 176.03155339805826 1.3643789213018729 0.3972771337532677 14.511319530749702 26.453870355965975 1.6568954592349954 0.4161874156663988 0.0617110857710017 0.0937351458200969 0.0234679865121522 0.0012416162119831 0.002518266790358 +Vesicles 51 291 2.1606728581978967 0.0307206189544912 63.69174757281554 303.19174757281553 0.3021616120018026 0.6308308858815788 16.21576692438533 35.60761931464484 1.2670437076534344 0.3993041904676221 0.4106937381366497 0.208330216775119 0.1669691328623625 0.2934135922918063 0.1576127145173894 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a8bae00f50862f39b05c31b29ecad610e9b67511 --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3093, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 142.21212121212122 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4c9032b9852cd81300f3380c8ccc3a14432d33e9 --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C176/C176_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b1d6b21a514c5b99ba1c38d07b009825653b03e5 --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,13 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Golgi apparatus 0.4696203787615309 3.550926981904579 0.0003838769015258 0.0125904386433018 0.0063339688751766 174 Q8IXU6,A4D1U4,Q5VW38,Q9NWM8,P11717,Q8NEY8,Q9HC07,P50897,O00231,P80303,Q8N4Q0,O14653,Q92896,Q9BUP0,Q5BJH7,O60637,O60476,P24390,Q92520,Q9NPR9,Q8NCH0,Q5KU26,P50570,Q9Y5P4,P09601,Q8IZA0,Q9GZM5,Q6ZRP7,Q9Y2V7,Q9BRK5,P53367,O00461,P07948,P83436,Q9HB40,O43760,Q9H3P7,O43290,O95456,O95302,Q93050 41 +Vesicles 0.3205905602027225 2.1606728581978967 0.0307206189544912 0.6428783720153345 0.2534451063745532 291 Q13614,Q9HD20,P42785,Q32P28,Q86YN1,Q6P1K2,P30519,P11717,O15118,Q96B26,Q9BTZ2,P50897,O75153,Q8NC96,P04114,Q8N4Q0,Q96K76,Q8IXH7,Q5BJH7,Q92791,Q8NHS3,P67809,P24390,Q9NRY5,Q6IQ22,Q8NCC3,Q8NBX0,Q9Y487,Q9NPR9,Q96M27,Q9UMR5,Q8N128,P13674,Q5KU26,Q15047,Q96J02,Q08722,Q9UFC0,Q6WKZ4,Q06481,P27105,Q13794,Q8WTV0,Q9NQZ2,P53367,O15126,P31751,Q96CN7,P51790,O95302,Q93050 51 +Centriolar satellite 0.5349660839850054 1.8402425609735904 0.0657326340085076 0.8939406617473624 0.3276460240492455 24 Q13045,Q03518,Q9P260,Q00013,Q86UY6,O43169 6 +Plasma membrane 0.3166057833116238 1.7036523361838665 0.088446057707932 0.9529219646897789 0.3299432594952142 263 Q8WUJ1,Q9BZF3,Q9NZL9,Q16181,P42694,Q69YU5,Q9NZ08,Q9Y4G8,Q16763,P41440,P67809,Q16625,O15173,Q13555,Q8TCG1,Q9Y487,P35241,Q9UQB8,P23634,P80723,P04899,Q9Y6M7,Q86XL3,Q08722,Q96F07,P09601,Q9H910,P27105,Q8TBX8,O60925,P08183,P07948,Q15758,Q14C86,Q9UEY8,Q5SWX8,Q66K14,Q96RT1,P55263 39 +Lysosomes 0.6128214879711049 1.5406563834760711 0.1234004374698676 0.9870448860823038 0.3299432594952142 11 O15400,P02786,Q8WTV0 3 +Actin filaments 0.357201903102534 0.9275129265775804 0.3536602833867044 0.9999994438296465 0.7231082192030112 46 Q16181,P42694,Q69YQ0,P67936,O75718,Q9P0K7,Q6P4Q7,Q8WWI1,P49006,P62312,Q9NYL9,P12814,P17812,P35580,Q15942,Q9HCD5,Q6WCQ1,P35579,Q96DB5,O00151 20 +Centrosome 0.3381316903381766 0.8878224562561152 0.3746362614587637 0.9999998127684884 0.7231082192030112 54 Q9UJW0,Q13564,Q3B7T1,P55081,Q9BSJ2,Q69YU5,Q9BRT9,Q9BRR6,P57740,Q96DB5,Q13561,P28074 12 +Intermediate filaments 0.3770223822442849 0.8154966273415931 0.4147880943231898 0.999999979042762 0.7231082192030112 32 P07196,Q15102,P08670,Q86YN1,O75718,Q9H974,Q3SXM5,Q8WXH0,Q96K76 9 +Focal adhesion sites 0.3206414607190054 0.3625370527451124 0.7169507399002688 1.0 0.8757528363121765 24 Q9Y487,P08183 2 +Endoplasmic reticulum 0.2664713933156084 0.3599241528010093 0.7189038544825226 1.0 0.8757528363121765 208 Q8WUJ1,Q00765,Q99956,P0CG08,Q8N0U8,Q5BJF2,Q92791,P23396,P67809,P43307,O95470,O43169,P13674,Q9H3G5,Q96HY6,Q9BRK0,Q86XL3,Q92575,Q96F07,P51571,Q12981,Q8IY17,Q14257,Q15631,Q03518,Q96CN7,P51572,O43852,Q6PIU2,Q16850,Q8NHH9,Q15800,Q96G23,O43731,P36578 35 +Cytokinetic bridge 0.3171153805814412 0.3413658299272253 0.7328281955871012 1.0 0.8757528363121765 24 Q96TC7,P07437,Q14203,Q96E11,Q9BVA1,Q9BUF5,Q53HL2,O75319 8 +Mitotic spindle 0.3158532634428777 0.2160463768618851 0.8289515975880861 1.0 0.9384090338869876 17 Q8IX90,P07437,Q14203,Q9BVA1,Q9BUF5,P52732 6 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0fcd61649536e7f5fc889ae528fff2a93d4d3b5f --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABAT", "ABCB1", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ADAR", "ADD1", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANF1", "BAP18", "BARD1", "BASP1", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf35", "C1orf52", "C2CD5", "C5orf15", "C5orf24", "C5orf51", "C8orf33", "CAAP1", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC59", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPI", "CENPP", "CENPQ", "CENPU", "CENPV", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHID1", "CHMP2A", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COQ8A", "COQ9", "COTL1", "COX15", "COX4I1", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CWC15", "CWC25", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DOLPP1", "DPF2", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "EMC8", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERH", "ERLIN1", "ERLIN2", "ERP29", "ESCO2", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FAF1", "FAF2", "FAHD1", "FAM114A2", "FAM120A", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM207A", "FAM208A", "FAM208B", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMC1", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR2", "GOT1", "GPAA1", "GPAM", "GPATCH8", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXIM1", "HGH1", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "IARS", "IARS2", "IBA57", "ICE2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "ISCU", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LETMD1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRWD1", "LSM12", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "MACF1", "MAEA", "MAGED2", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD8", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEFL", "NEFM", "NELFA", "NELFCD", "NELFE", "NEPRO", "NES", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C3A", "NT5DC1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCNP", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGL", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PUS1", "PWP1", "PWP2", "PWWP2A", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB32", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "RP2", "RPA1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSRC1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX2", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPC25", "SPCS2", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STRN4", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THEM6", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THYN1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMMDC1", "TJP1", "TKT", "TLE3", "TLN1", "TM7SF2", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED8", "TMEM109", "TMEM126A", "TMEM126B", "TMEM165", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM223", "TMEM230", "TMEM245", "TMEM70", "TMEM97", "TMF1", "TMOD3", "TMPPE", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TST", "TTC1", "TTC19", "TTC37", "TTC4", "TTF1", "TTLL12", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUFM", "TWISTNB", "TXLNA", "TXLNG", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBFD1", "UBIAD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF3B", "UQCC1", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "UROD", "USMG5", "USO1", "USP10", "USP14", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR77", "WDR82", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZDHHC20", "ZEB2", "ZFR", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF148", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF644", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ACBD3", "ACTN1", "ADD3", "ADK", "ADPGK", "AKT2", "ANKLE2", "APLP2", "APOB", "ARFIP1", "ATL2", "ATP13A1", "ATP2B4", "ATP6V0A1", "ATP6V0A2", "BAIAP2", "BASP1", "BCAP31", "BNIP1", "C12orf73", "CALU", "CAMK2G", "CD47", "CDCA8", "CERS2", "CHST14", "CIP2A", "CLCN3", "CLUH", "CNNM4", "COG6", "COG7", "COL4A3BP", "COLEC12", "CPVL", "CRTAP", "CTPS1", "CYB5B", "CYB5D2", "CYFIP2", "CYP51A1", "DCTN1", "DCTN2", "DCTN4", "DDRGK1", "DHRS4", "DNM2", "DOLPP1", "DUSP11", "DUSP9", "EDRF1", "EFHD1", "ERAP1", "ERBIN", "EXOSC8", "FAM114A2", "FAM177A1", "FAM3C", "FKBP14", "FKBP9", "FLII", "GAPVD1", "GINS4", "GLG1", "GNAI2", "GOLIM4", "GOSR2", "GPR107", "GPR108", "GPR89B", "HELZ", "HMOX1", "HMOX2", "HSDL1", "IGF2R", "ISOC1", "ITCH", "JPT2", "KDELR1", "KDELR3", "KIAA0319L", "KIAA1147", "KIAA1468", "KIF11", "LMO7", "LRWD1", "LSM6", "LYN", "MAN1A2", "MARCKSL1", "MAT2B", "MFAP1", "MFSD8", "MPP1", "MPRIP", "MRRF", "MSMO1", "MTMR2", "MYH10", "MYH9", "NAA40", "NAE1", "NCEH1", "NCOA5", "NECAP1", "NEFL", "NELFCD", "NPC1", "NUCB2", "NUP107", "OCLN", "ODR4", "OSBPL6", "P3H1", "P3H4", "P4HA1", "PAFAH1B3", "PDLIM1", "PFDN1", "PGRMC2", "PIP4K2C", "PLA2G15", "PMAIP1", "PMF1", "PNPLA6", "PPHLN1", "PPT1", "PPT2", "PRCP", "PRRC1", "PSMB5", "PSMD11", "PSMG1", "QSOX2", "QTRT2", "RAB11FIP1", "RAB12", "RAI14", "RAPGEF2", "RCN2", "RDX", "REEP2", "REEP5", "RMDN1", "RMDN3", "RPL4", "RPS3", "SART1", "SCAMP1", "SCARB1", "SCCPDH", "SCPEP1", "SDF4", "SEPT7", "SETDB1", "SGPL1", "SKA3", "SLC19A1", "SLC1A5", "SLC35F2", "SLC4A7", "SPECC1L", "SSR1", "SSR4", "STOM", "STX7", "SYNE2", "SYNGR2", "TAP1", "TBC1D9B", "TFRC", "TMEM165", "TMEM97", "TMOD3", "TPM4", "TSN", "TSPAN3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "UBE2S", "UBXN4", "USP47", "UTP3", "VIM", "VKORC1L1", "YBX1", "YIF1B", "YIPF3", "ZADH2", "ZYX"]} \ No newline at end of file