diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..853ec9fee62edeb00f1633c7d9a6185e4ac410ff --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:02131b116f82e6e807c05289b7aae5bdaca5e1fde0e4a938cf7867e1bfc00813 +size 77969 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..dc5f7ea4c397fc6bf23183e764449ba3ff8ff5ba --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 56, + "title": "Average number of proteins per term", + "value": 2.375 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3af4693ea32f7e2d10d215d02365cbae6a6bf6a3 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dca7271971a6938d00c4497eaf82ff26d0e72fe4 --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Histidine acid phosphatase active site [IPR033379] 0.9625322997415984 1.679592201764284 0.0930366859860589 0.995782798526063 0.1929649783414556 2 Q9NPH0 1 +Serine carboxypeptidase, serine active site [IPR018202] 0.8400646203554267 1.128023075105343 0.25931017410517 0.999999949923123 0.4400415075724097 3 Q9HB40,Q9H3G5 2 +ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003] 0.4379200563021249 0.2321943072233575 0.8163870991235236 1.0 0.8625976896399494 4 P06576 1 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..95ac9ee2d2dd7fbf68b5d59481b6dcfa23cd69e3 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine proteases, trypsin family, histidine active site [IPR018114]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CHEK1", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP11", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAPK1", "MDH1", "MDH2", "MTMR2", "NCEH1", "NEK9", "NME1", "NME6", "OXCT1", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKCA", "PRKCB", "PRPF4B", "PRSS3", "PTK7", "PTPMT1", "PTPN1", "PTPN9", "RIPK1", "RNASET2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "VRK2", "YES1"], "leading_proteins": ["ACP6", "ATP5B", "CPVL", "SCPEP1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b6823bbba9d9434ba0a91b639df477220943322c --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:32a2e8534ccd610024253419600ce9841162a7a38fd4b0bab65b46b01914c23e +size 140541 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..1628bc7374c536c372a577618c630dc0138084bf --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bfcd0958b0b44b340ef332f64fe597613c268346d50e0f16f334b8cfe31242ae +size 71234 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..3215fabed3097e145d7a06ae6cba378577909cc8 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 29, + "title": "Average number of proteins per term", + "value": 4.275862068965517 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4fcb2f503367ba7ea5f18f3581ade4781328ff69 --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..98fb07c8492d29ad1f30dbe46cd22ecf78d15a20 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Peptidase M16, zinc-binding site [IPR001431] 0.6455060247964413 1.170774229144595 0.2416895391702949 0.9996722336495591 0.4331678136194573 5 Q10713,P22695 2 +Beta tubulin, autoregulation binding site [IPR013838] 0.8436187399030685 1.1408653522521912 0.2539259597079577 0.9997955081804496 0.4331678136194573 3 P07437,Q9BVA1 2 +EF-Hand 1, calcium-binding site [IPR018247] 0.3403469902613198 0.5627599766612554 0.5735983373296456 0.9999999999816028 0.6653740713023889 36 Q02818,O95202,P80303,Q14257,Q9BRK5,P41208,O95302,Q9NWM8 8 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6b30e2035b148823112ce60be8f22561b40ac405 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "AURKB", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CETN2", "CHEK1", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP14", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LPCAT2", "LYN", "MACF1", "MAPK1", "MCCC1", "MICU1", "MYH10", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "PA2G4", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKAA2", "PRKCA", "PRKCB", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "TKT", "TUBB", "TUBB2B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["CETN2", "FKBP14", "FKBP9", "LETM1", "NUCB1", "NUCB2", "PMPCA", "RCN2", "SDF4", "TUBB", "TUBB2B", "UQCRC2"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..006ed1423bd766d7c2fceea23f15ffb49217a050 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Syntaxin/epimorphin, conserved site [IPR006012]", "1": "Proteasome beta-type subunit, conserved site [IPR016050]", "2": "ABC transporter-like, conserved site [IPR017871]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a912e4664297c730a7cd8b7e43532c2b0ad26073 --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c1d7fe4299e7acf4a404c8e26f8fafab397eb324c88a2da5ab2e1e6c70466ddc +size 138021 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..641557b4d7849d2fdf875ca5cfdba0d823faae8e --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6a9a9f9b70a845f0e0497bd59b71110f3c3f9ae953828645168941c1ac43b4bf +size 142842 diff --git a/interpro_conserved_site/basic/plot_2.png b/interpro_conserved_site/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..ff8684c2306449137057997ee512bc6fcaf1b1f7 --- /dev/null +++ b/interpro_conserved_site/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:21745034517549f37e3dbd1d0946f074a2ff45d8f5557e35cdd43e0afc836d3f +size 140311 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..cc54381d6f94264a755fb658d84dd5bac72f29c6 --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b0554617a84bb16c5547cc155885808fb4f7521a33122d6de253abc7f900d2ae +size 94729 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..248d110d75c8b56092ba84c294006e0d97665450 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 277, + "title": "Average number of proteins per term", + "value": 2.6823104693140793 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f4bdec982bb9c57ae7c95c2de5661003de272079 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f781e553e2f8f5899463084a7ed8d45f102c7d5e --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,18 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Syntaxin/epimorphin, conserved site [IPR006012] 0.7591446973848249 1.898593345718718 0.0576179640061265 0.9999999274096848 0.2280025147099577 7 O43752,O15400,Q13277,Q9P2W9,O60499 5 +Haem oxygenase conserved site [IPR018207] 0.9757751937984468 1.732204000597203 0.0832372470036126 0.9999999999649104 0.2900241182447184 2 P30519 1 +Proteasome beta-type subunit, conserved site [IPR016050] 0.6800940016086875 1.688106957380287 0.0913906991549711 0.9999999999970456 0.2978261607756117 8 P28074,P28072,P49721,P28070,P20618 5 +ABC transporter-like, conserved site [IPR017871] 0.6021504808539841 1.6585367630484638 0.0972091736004534 0.9999999999995016 0.2998305907682788 12 Q03518,O14678,P08183,P33527,O75027 5 +Thioredoxin, conserved site [IPR017937] 0.5998736681083771 1.548880483158928 0.12141045341217 0.9999999999999998 0.3085384916988175 11 Q8IXB1,Q9H1E5 2 +Tetraspanin, conserved site [IPR018503] 0.9192506459948232 1.5072088176986629 0.1317571407881947 1.0 0.3243648938520267 2 O60637 1 +Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.928583856161466 1.4499247473571135 0.1470795054014719 1.0 0.3245875917582254 3 Q8N4Q0 1 +C-type lectin, conserved site [IPR018378] 0.863372093023243 1.2848007967693271 0.198861903877912 1.0 0.3889065546905323 2 Q5KU26 1 +Intermediate filament protein, conserved site [IPR018039] 0.5737403892714299 1.1787656205384622 0.2384915176071125 1.0 0.4494023835181644 8 P08670,P07196,P20700 3 +Tubulin, conserved site [IPR017975] 0.8436187399030685 1.1408653522521912 0.2539259597079577 1.0 0.4720636969067402 3 P07437,Q9BVA1 2 +Heavy-metal-associated, conserved site [IPR017969] 0.7729328165374701 0.931985043672298 0.3513442548847139 1.0 0.5724844623709751 2 P35670 1 +Guanylate kinase, conserved site [IPR020590] 0.4420980702300843 0.2428011249188632 0.8081594640855625 1.0 0.8954406862068033 4 Q9NZW5 1 +Aldehyde dehydrogenase, cysteine active site [IPR016160] 0.3428328567513051 0.1140232154897451 0.909219390162152 1.0 0.9724083825286338 7 P51648 1 +Ribosomal protein L24e, conserved site [IPR023442] 0.4463824289405695 0.0920173335635597 0.9266842678267944 1.0 0.9872751622616232 2 Q9UHA3 1 +Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.4481421647818978 0.0798732856599932 0.936338036884262 1.0 0.9937380697967072 3 Q9BXS5,Q9Y2T2 2 +DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514] 0.3779069767441838 0.0564707970197855 0.9549667589919276 1.0 0.9947579917550416 2 O15160 1 +Heat shock protein Hsp90, conserved site [IPR019805] 0.406462035541178 0.0477960911146797 0.9618787518364572 1.0 0.9947579917550416 3 P08238,P07900 2 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ce9a750fb4490d56feebe3aec1e506ddf929d125 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycerate/sugar phosphate transporter, conserved site [IPR021159]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinate dehydrogenase, cytochrome b subunit, conserved site [IPR018495]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APLP2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7A", "ATP7B", "BAG6", "BAK1", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BLM", "BMI1", "BOP1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDKAL1", "CECR2", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX38", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "EPS15", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FTL", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GFM2", "GLA", "GLB1", "GLB1L2", "GLO1", "GNPDA1", "GNS", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXD11", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPAD1", "IMPDH2", "INA", "ING5", "IQGAP1", "IQGAP2", "ITGAV", "IVD", "KDM2A", "KDSR", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MOCS1", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPST", "MRC2", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSD3", "NSF", "NTHL1", "NUBP1", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PHF2", "PHF3", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SDHC", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A2", "SLC27A4", "SLC2A1", "SLC37A4", "SLC4A2", "SLC5A6", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STMN1", "STOM", "STRN", "STRN4", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TM7SF2", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP13", "TSFM", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBFD1", "UHRF1", "USP10", "USP14", "USP19", "USP36", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCB7", "ABCC1", "ABCD4", "ALDH3A2", "AP1M1", "AP3M1", "ATP7B", "COLEC12", "DNAJC10", "HMOX2", "HSP90AA1", "HSP90AB1", "LMNB1", "MPP6", "NEFL", "POLR1C", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "RSL24D1", "STX10", "STX18", "STX3", "STX6", "STX7", "TAP1", "TMX4", "TSPAN3", "TUBB", "TUBB2B", "VIM", "ZADH2"]} \ No newline at end of file diff --git a/interpro_domain/advanced/idx2term.json b/interpro_domain/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_domain/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_domain/basic/idx2term.json b/interpro_domain/basic/idx2term.json new file mode 100644 index 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@@ +version https://git-lfs.github.com/spec/v1 +oid sha256:31a70f9c4cb5bf3cdf135e6f2493d308e375a7b98cd6b1e9c550bbd2b7687abe +size 148942 diff --git a/interpro_domain/basic/plot_9.png b/interpro_domain/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..cc7c685498ad76c696041169e82af4a59f0d964f --- /dev/null +++ b/interpro_domain/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4e36043c812942da6a753e1416a07c927c9cde8c6411197c593f91404c74ad71 +size 133014 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..f73ce42d1ba214393489d0c7e3dc7742ac2d8140 --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:92b15f0f7f64efcc7455713c1ca813b2437c10fb7eeba18aa031a7fb714446ad +size 322182 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7b1adfa1cf8e69b8ece1d25a647fd011d39690c6 --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 3 6 2.3897370946713883 0.0168604372934824 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 3.811917339060444e-05 0.0014481500629001 0.0001833288791406 0.000142755965642 0.0019884945269669 +Glutathione S-transferase, N-terminal [IPR004045] 1 8 2.2834458860600946 0.0224041169788014 2.4635922330097086 7.354368932038835 0.1379245375050955 0.5007649291980636 1.692684060559357 0.9479949918991396 0.9964823876403148 0.2990443112345751 0.0147099496631327 0.0012105019492812 0.0048484802924912 0.027832231049335 0.0968157430558884 +Glutathione S-transferase, C-terminal-like [IPR010987] 1 11 2.036007480931588 0.041749604075012 3.949029126213592 11.37621359223301 -0.0908035435769439 0.5323098181486043 2.6346872162188446 1.2313530457632356 0.9588413776865506 0.2992576122582335 0.0303360476395803 0.0026008925831016 0.0102498345034834 0.0561137872346343 0.1807018090276839 +Polyketide synthase, enoylreductase domain [IPR020843] 1 5 2.0272227019791127 0.0426396424699231 1.6189320388349515 6.283980582524272 0.4837477775906041 0.3583565743712875 1.2357658783365448 1.1656223303878015 1.2317099658487027 0.2921137785685181 0.0147099496631327 1.0 0.1018169846714528 0.027832231049335 0.0968157430558884 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..df92c8e3538371ad93480e97631df86cfc0ec29b --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 2495, + "title": "Average number of proteins per term", + "value": 2.171142284569138 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e481a85de7342f3edc2ca2ef8e29aac26e5875b1 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4fd11dab3c280336e1df42f578eaf2120d9261e5 --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,208 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.8969836854872061 2.3897370946713883 0.0168604372934824 1.0 0.1208815834690764 6 Q9UMX5,O43169,Q8WUJ1 3 +Glutathione S-transferase, N-terminal [IPR004045] 0.8109072229825439 2.2834458860600946 0.0224041169788014 1.0 0.1355594432261878 8 Q9H7Z7 1 +Glutathione S-transferase, C-terminal-like [IPR010987] 0.6932167133693996 2.0360074809315876 0.041749604075012 1.0 0.1799054614285925 11 Q9H7Z7 1 +Polyketide synthase, enoylreductase domain [IPR020843] 0.8495989136466542 2.0272227019791127 0.0426396424699231 1.0 0.1827936562928835 5 Q8N4Q0 1 +Target SNARE coiled-coil homology domain [IPR000727] 0.7170544907899895 1.9522444565384327 0.0509091883747767 1.0 0.2022586385271783 9 O43752,O15400,Q13277,O60499,Q9UNK0 5 +Major facilitator superfamily domain [IPR020846] 0.781471628614007 1.9100823274275105 0.0561226140579345 1.0 0.2150935822957705 6 P53985,Q8NHS3,Q9H2V7 3 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.7049311463738145 1.894560041419152 0.0581507128361031 1.0 0.2188326222112782 9 Q04656,P16615,P98194,Q9HD20,P35670,P20020,P23634 7 +ABC transporter type 1, transmembrane domain [IPR011527] 0.6960340857549782 1.8519977584906195 0.0640261447835532 1.0 0.23069110504081 9 Q03518,O14678,P08183,P33527,O75027 5 +Sterile alpha motif domain [IPR001660] 0.7480734536598245 1.8499549939435809 0.0643200365728788 1.0 0.2312370190912576 7 Q15375,Q13586 2 +LEM domain [IPR003887] 0.7460473978188771 1.7578670224234323 0.0787701381340229 1.0 0.2627167738661094 6 Q86XL3,P50402 2 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.7786366931692127 1.7353059191754268 0.0826866338861762 1.0 0.2707591662839105 5 P55786,Q9UIQ6,Q9NZ08 3 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.7786366931692127 1.7353059191754268 0.0826866338861762 1.0 0.2707591662839105 5 P55786,Q9UIQ6,Q9NZ08 3 +Alcohol dehydrogenase, N-terminal [IPR013154] 0.7704420683021054 1.7010979162749131 0.0889246021399925 1.0 0.2822733872001035 5 Q8N4Q0 1 +Reticulon [IPR003388] 0.8274078862314163 1.6671027731892498 0.0954939708150015 1.0 0.2887963243398979 4 Q9NQC3,O95197,O75298 3 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.7620433236340269 1.6659404564179647 0.09572527464092 1.0 0.2887963243398979 5 P98194,P20020,P16615,P23634 4 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.7620433236340269 1.6659404564179647 0.09572527464092 1.0 0.2887963243398979 5 P98194,P20020,P16615,P23634 4 +ABC transporter-like, ATP-binding domain [IPR003439] 0.6021504808539841 1.6585367630484638 0.0972091736004534 1.0 0.2922131182326883 12 Q03518,O14678,P08183,P33527,O75027 5 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.8199642856976035 1.6377157555678998 0.1014810023626409 1.0 0.2985791284136663 4 Q96CP7,Q96G23 2 +GOLD domain [IPR009038] 0.659842211459019 1.5925593675258976 0.1112590749263782 1.0 0.312955346044322 8 Q15363,Q9H3P7,Q9Y3B3 3 +Prenylcysteine lyase [IPR010795] 0.9360465116279038 1.5741551213958738 0.1154515918014289 1.0 0.3179378824995201 2 Q9UHG3 1 +Marvel domain [IPR008253] 0.934431524547804 1.567719642154324 0.1169465755915819 1.0 0.3213454913006575 2 O43760 1 +GMP phosphodiesterase, delta subunit [IPR008015] 0.933139534883718 1.562570910628414 0.1181535548519736 1.0 0.3243048617774194 2 A6NIH7 1 +BAG domain [IPR003103] 0.800407434523022 1.5602522330945376 0.1187002865553932 1.0 0.3254474889623144 4 O95817,Q9UL15 2 +Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.9292635658914672 1.547123096779732 0.1218335654583904 1.0 0.3280418436547405 2 Q13505 1 +Metaxin, glutathione S-transferase domain [IPR033468] 0.9292635658914672 1.547123096779732 0.1218335654583904 1.0 0.3280418436547405 2 Q13505 1 +Syntaxin 6, N-terminal [IPR015260] 0.9173126614987084 1.499482921888743 0.1337483959162941 1.0 0.3461641574804502 2 O60499 1 +ERAP1-like C-terminal domain [IPR024571] 0.9350565428109848 1.473512461634797 0.1406129061548973 1.0 0.3558105485359724 3 P55786,Q9UIQ6 2 +Phospholipid/glycerol acyltransferase [IPR002123] 0.6111424066899058 1.436849266292248 0.1507608281902226 1.0 0.3692227583332823 9 Q9HCL2 1 +GINS subunit, domain A [IPR021151] 0.8924418604651168 1.4003678148940517 0.161403202840157 1.0 0.3845033310862072 2 Q9BRX5 1 +Choline/carnitine acyltransferase domain [IPR039551] 0.8879198966408282 1.3823627897839132 0.1668603353918549 1.0 0.3934938911178432 2 P23786 1 +Cysteine-rich flanking region, C-terminal [IPR000483] 0.8821059431524467 1.3592256528914348 0.1740750947610689 1.0 0.4036406704729248 2 Q13641 1 +Leucine-rich repeat N-terminal domain [IPR000372] 0.8821059431524467 1.3592256528914348 0.1740750947610689 1.0 0.4036406704729248 2 Q13641 1 +Glycosyltransferase 2-like [IPR001173] 0.7458952994859267 1.3428475361091792 0.1793213473689086 1.0 0.4112194500785174 4 O60762 1 +BTB/Kelch-associated [IPR011705] 0.8717700258397851 1.3181356712664063 0.1874582352008236 1.0 0.4248031760454631 2 Q14145 1 +C-type lectin-like [IPR001304] 0.863372093023243 1.2848007967693271 0.198861903877912 1.0 0.4371457710796392 2 Q5KU26 1 +CD209-like, C-type lectin-like domain [IPR033989] 0.863372093023243 1.2848007967693271 0.198861903877912 1.0 0.4371457710796392 2 Q5KU26 1 +Cyclic nucleotide-binding domain [IPR000595] 0.671202445570381 1.2806828501098733 0.2003050859762252 1.0 0.4399306245692622 5 Q9Y4G8,Q8IY17 2 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.8601421188630448 1.2719941611518686 0.2033751938393333 1.0 0.444129642881269 2 Q5T9A4 1 +BTB/POZ domain [IPR000210] 0.6645366605948521 1.2521800353805967 0.21050426910362 1.0 0.4508224475652636 5 Q14145,O43791 2 +Pleckstrin homology domain [IPR001849] 0.4673928942386233 1.218861057972788 0.2228969322440641 1.0 0.4700996161867625 18 P31751,Q9BZF3,Q6WCQ1,P50570 4 +Intermediate filament head, DNA-binding domain [IPR006821] 0.7132604832907118 1.2122021214011802 0.225435019642632 1.0 0.4724536784633355 4 P08670 1 +Band 7 domain [IPR001107] 0.5779136080481719 1.1990186270273984 0.2305207027853959 1.0 0.478095721903211 8 O75955,Q9UJZ1,Q14254,Q99623,P35232,P27105 6 +Intermediate filament, rod domain [IPR039008] 0.5737403892714299 1.1787656205384622 0.2384915176071125 1.0 0.4888093798799528 8 P08670,P07196,P20700 3 +CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.8523579513866988 1.1724923305145685 0.2409994495128742 1.0 0.488924792324792 3 Q9NUQ9 1 +Tripartite DENN domain [IPR037516] 0.830426356589151 1.154677578337873 0.2482224846402783 1.0 0.4932113780795123 2 A4D1U4 1 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.8436187399030685 1.1408653522521912 0.2539259597079577 1.0 0.4980701804020083 3 P07437,Q9BVA1 2 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.8436187399030685 1.1408653522521912 0.2539259597079577 1.0 0.4980701804020083 3 P07437,Q9BVA1 2 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.8255813953488373 1.1356577807837756 0.2560998164765062 1.0 0.4988048728406581 2 O60506 1 +Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141] 0.8149224806201565 1.0939485304493797 0.2739775524452521 1.0 0.5186488182576783 2 P20020 1 +HIT-like domain [IPR011146] 0.8123385012919928 1.083867506590604 0.278423548499886 1.0 0.5231789257193876 2 Q9NQE9 1 +Cold shock domain [IPR011129] 0.8210160189853875 1.0594300282460425 0.2894039801917309 1.0 0.5309286254252712 3 P16989 1 +Cold-shock protein, DNA-binding [IPR002059] 0.8210160189853875 1.0594300282460425 0.2894039801917309 1.0 0.5309286254252712 3 P16989 1 +Cold-shock (CSD) domain [IPR019844] 0.8210160189853875 1.0594300282460425 0.2894039801917309 1.0 0.5309286254252712 3 P16989 1 +Exosome complex component, N-terminal domain [IPR025721] 0.8045865633074921 1.053702498488141 0.2920191446944054 1.0 0.531811348514237 2 Q13868 1 +FAD-binding domain, PCMH-type [IPR016166] 0.800387596899208 1.0374152180986391 0.2995423890354445 1.0 0.53892393267509 2 Q15392 1 +FAD linked oxidase, N-terminal [IPR006094] 0.800387596899208 1.0374152180986391 0.2995423890354445 1.0 0.53892393267509 2 Q15392 1 +Class II aldolase/adducin N-terminal [IPR001303] 0.7990956072351465 1.0324115365961235 0.3018793697753894 1.0 0.5397792376254353 2 Q9UEY8 1 +Dynamin, N-terminal [IPR045063] 0.5658996528842722 1.02177192400549 0.3068888605480155 1.0 0.5426416587127186 7 P50570,Q8IWA4,O00429,O60313,Q9H4M9 5 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.5658996528842722 1.02177192400549 0.3068888605480155 1.0 0.5426416587127186 7 P50570,Q8IWA4,O00429,O60313,Q9H4M9 5 +Glutamine amidotransferase type 2 domain [IPR017932] 0.7884366925064641 0.9912806818130996 0.3215485432970255 1.0 0.5538462645739038 2 Q06203 1 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.7877906976744227 0.988796917952347 0.3227625125011848 1.0 0.5538462645739038 2 P10321 1 +MHC class I, alpha chain, C-terminal [IPR010579] 0.7877906976744227 0.988796917952347 0.3227625125011848 1.0 0.5538462645739038 2 P10321 1 +Fibronectin type II domain [IPR000562] 0.7993035655834033 0.9818548582890252 0.3261713575818274 1.0 0.5581344461814438 3 Q9UBV2 1 +Rpn11/EIF3F, C-terminal [IPR024969] 0.6467307046524764 0.9474854579057737 0.3433914629436239 1.0 0.5765556527889244 4 P51665 1 +Glycosyl transferase, family 1 [IPR001296] 0.7866491767224918 0.9370236941034936 0.3487463700723365 1.0 0.5824111066469074 3 Q9BT22 1 +Heavy metal-associated domain, HMA [IPR006121] 0.7729328165374701 0.931985043672298 0.3513442548847139 1.0 0.5855737581411898 2 P35670 1 +Heavy metal-associated domain, copper ion-binding [IPR006122] 0.7729328165374701 0.931985043672298 0.3513442548847139 1.0 0.5855737581411898 2 P35670 1 +LEM-like domain [IPR013146] 0.7722868217054217 0.9295294927150526 0.3526147481541459 1.0 0.5869071358536319 2 P42167 1 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.5058693790016298 0.9076166141570242 0.3640808133481685 1.0 0.5921653385291268 9 Q9NWM8 1 +Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.7754442649434763 0.8976089101081696 0.3693940871273908 1.0 0.5959320663003574 3 Q96RQ1,Q9Y282 2 +Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.7754442649434763 0.8976089101081696 0.3693940871273908 1.0 0.5959320663003574 3 Q96RQ1,Q9Y282 2 +Ion transporter-like, CBS domain [IPR044751] 0.7587209302325575 0.8782733634943279 0.3797953873089978 1.0 0.6032143247746623 2 Q6P4Q7 1 +CNNM, transmembrane domain [IPR002550] 0.7587209302325575 0.8782733634943279 0.3797953873089978 1.0 0.6032143247746623 2 Q6P4Q7 1 +UBX domain [IPR001012] 0.7678619081748348 0.8711055732350578 0.3836965113449868 1.0 0.606401516781734 3 Q92575 1 +CBS domain [IPR000644] 0.5448074517157748 0.8652096786352822 0.3869237140843025 1.0 0.6098387028681836 6 Q6P4Q7,P51790,Q8NE01 3 +Peptidase M16, C-terminal [IPR007863] 0.5248213436628226 0.8331140100141847 0.4047804329240341 1.0 0.6234243557417649 7 Q10713,P22695 2 +Peptidase M16, N-terminal [IPR011765] 0.5248213436628226 0.8331140100141847 0.4047804329240341 1.0 0.6234243557417649 7 Q10713,P22695 2 +Zinc finger C2H2 AKAP95-type [IPR034736] 0.7457033052923724 0.7945547304270176 0.4268725604158545 1.0 0.6418511604538844 3 Q5BKZ1 1 +Syntaxin, N-terminal domain [IPR006011] 0.7446619813586999 0.790993935096976 0.4289475306466399 1.0 0.6418511604538844 3 Q13277 1 +Peptidase M28 [IPR007484] 0.7445738361458647 0.7906926861508039 0.4291233450762497 1.0 0.6418511604538844 3 Q7Z2K6 1 +Ricin B, lectin domain [IPR000772] 0.6041444876600569 0.7818803269034897 0.4342849077273178 1.0 0.6418511604538844 4 Q9UBG0 1 +MHC class I-like antigen recognition-like [IPR011161] 0.7418001997693924 0.7812265093277032 0.4346692848435463 1.0 0.6418511604538844 3 P10321 1 +Immunoglobulin C1-set [IPR003597] 0.7418001997693924 0.7812265093277032 0.4346692848435463 1.0 0.6418511604538844 3 P10321 1 +FAD dependent oxidoreductase [IPR006076] 0.5991195414546138 0.7626856297241378 0.4456509027479907 1.0 0.650440995431678 4 Q9H9P8,Q96CU9 2 +DALR anticodon binding [IPR008909] 0.7238372093023263 0.7496916944664244 0.4534404108937038 1.0 0.6550861755528611 2 P54136 1 +Arginyl-tRNA synthetase, catalytic core domain [IPR035684] 0.7238372093023263 0.7496916944664244 0.4534404108937038 1.0 0.6550861755528611 2 P54136 1 +RBM1CTR [IPR012604] 0.7225452196382414 0.745033380508033 0.456251540613759 1.0 0.6583849588382469 2 Q96E39 1 +Ras-associating (RA) domain [IPR000159] 0.7199612403100824 0.7357416899994529 0.4618879130745434 1.0 0.6616463637869061 2 Q9Y4G8 1 +Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958] 0.724717285945077 0.7235208398033739 0.4693599554444718 1.0 0.668409297279656 3 Q9NR33,Q9NRF9 2 +Dynamin, GTPase domain [IPR001401] 0.7186814870043525 0.7033973773433715 0.4818081405066157 1.0 0.6783515726276605 3 P50570 1 +Chromo shadow domain [IPR008251] 0.701992860316123 0.6485652041112128 0.5166194524299086 1.0 0.6948601260445402 3 P83916 1 +Chromo domain subgroup [IPR017984] 0.701992860316123 0.6485652041112128 0.5166194524299086 1.0 0.6948601260445402 3 P83916 1 +NOPS [IPR012975] 0.7001615508885304 0.642625525923114 0.5204671158385099 1.0 0.697778320267105 3 Q15233,P23246 2 +Myotubularin-like phosphatase domain [IPR010569] 0.6912144702842262 0.6348307134611986 0.5255388296307872 1.0 0.7017455009570894 2 Q9C0I1 1 +KHDRBS, Qua1 domain [IPR032571] 0.6895994832041343 0.6293077334561744 0.5291476094071998 1.0 0.7019238779765953 2 O75525 1 +Sam68, tyrosine-rich domain [IPR032335] 0.6895994832041343 0.6293077334561744 0.5291476094071998 1.0 0.7019238779765953 2 O75525 1 +Chromatin target of PRMT1 protein, C-terminal [IPR025715] 0.6886304909560743 0.6260020246188512 0.5313136133574996 1.0 0.7019238779765953 2 Q86V81 1 +SLC12A transporter, C-terminal [IPR018491] 0.6873385012919848 0.6216039295189206 0.5342023365230297 1.0 0.7019238779765953 2 Q9BXP2 1 +Amino acid permease/ SLC12A domain [IPR004841] 0.6873385012919848 0.6216039295189206 0.5342023365230297 1.0 0.7019238779765953 2 Q9BXP2 1 +Zinc finger, CHHC-type [IPR012996] 0.6927302100161581 0.6186906070214698 0.5361201990412408 1.0 0.7029460991566808 3 P52597,P31943 2 +Dbl homology (DH) domain [IPR000219] 0.6821705426356465 0.6041223163974845 0.5457623235681066 1.0 0.7118018804508239 2 Q9Y4F1 1 +Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 0.4643275190785022 0.5635479057403918 0.5730618486112706 1.0 0.7330280213896413 7 Q15375 1 +PABP, RNA recognition motif 2 [IPR045305] 0.6592377260981932 0.528841623215299 0.5969153208822118 1.0 0.7453972600606198 2 P11940 1 +Man1/Src1, C-terminal [IPR018996] 0.6563307493540071 0.519585830964695 0.6033522757886349 1.0 0.7489372776580319 2 Q9Y2U8 1 +SET domain [IPR001214] 0.4164890629472237 0.5163250631280207 0.6056273942022492 1.0 0.7495239824080415 10 Q15047 1 +Zinc finger, RanBP2-type [IPR001876] 0.4498115859778113 0.5016339029023796 0.6159250666607621 1.0 0.7526639630412686 7 P98175,Q92804 2 +CARG-binding factor, N-terminal [IPR012956] 0.6437338501291996 0.4802866126844529 0.6310236067885993 1.0 0.7589437769401177 2 Q99729 1 +Radical SAM [IPR007197] 0.6476296521659506 0.480058626627432 0.6311857062728434 1.0 0.7589437769401177 3 Q5VV42 1 +Elp3/MiaB/NifB [IPR006638] 0.6476296521659506 0.480058626627432 0.6311857062728434 1.0 0.7589437769401177 3 Q5VV42 1 +FAD/NAD(P)-binding domain [IPR023753] 0.4757526261561703 0.4746686544307156 0.6350231633074439 1.0 0.7606254404474664 5 O95831 1 +Proteasome activator PA28, N-terminal domain [IPR003185] 0.6445912186715317 0.4711836771875148 0.6375095740198997 1.0 0.7628711689111031 3 Q9UL46 1 +Proteasome activator PA28, C-terminal domain [IPR003186] 0.6445912186715317 0.4711836771875148 0.6375095740198997 1.0 0.7628711689111031 3 Q9UL46 1 +Staufen, C-terminal [IPR032478] 0.6310177705977369 0.4323512820127358 0.6654861206259013 1.0 0.7797415687152547 3 O75569,Q9NUL3 2 +Immunoglobulin-like domain [IPR007110] 0.3907084028551533 0.4272425447619731 0.669202676234576 1.0 0.7820424717589073 11 P35613,Q08722,P10321 3 +OCRE domain [IPR041591] 0.6211856366377034 0.4050967266458958 0.685406412499677 1.0 0.7943413033745038 3 P78332 1 +v-SNARE, coiled-coil homology domain [IPR042855] 0.6210016155088877 0.404593932804475 0.6857760190255235 1.0 0.7943413033745038 3 O75396,P51809 2 +Longin domain [IPR010908] 0.6210016155088877 0.404593932804475 0.6857760190255235 1.0 0.7943413033745038 3 O75396,P51809 2 +Rho GTPase-activating protein domain [IPR000198] 0.6166020671834663 0.4004963615861988 0.6887909627829749 1.0 0.7970934379144352 2 O00459 1 +Armadillo repeat-containing domain [IPR006911] 0.6146640826873275 0.3950702572013099 0.6927910384833655 1.0 0.8000233707084407 2 Q8N2F6 1 +Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798] 0.6101421188630354 0.3825589054401538 0.7020468450813357 1.0 0.8042272169320168 2 Q9UKA9 1 +EF-hand domain [IPR002048] 0.3283510933178334 0.3816407833335247 0.7027278291197019 1.0 0.8045501456222576 44 Q02818,O95202,P80303,Q14257,Q9BRK5,P41208,O95302,O75746,Q9NWM8,Q9UJS0 10 +JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.415894845420131 0.3636061786497294 0.7161521122727474 1.0 0.8155037117771547 7 O00303,P51665 2 +LSM domain, eukaryotic/archaea-type [IPR001163] 0.3838847010020122 0.361651951067913 0.7176121373421038 1.0 0.815674364550791 10 P62310,Q9Y4Y9 2 +Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004] 0.6012924071082432 0.3523795556538286 0.7245536321997357 1.0 0.8161450620037655 3 Q13310,P11940 2 +Immunoglobulin I-set [IPR013098] 0.5978682170542687 0.3496845287417023 0.7265754658047769 1.0 0.817684162013044 2 P13591 1 +Glycoside hydrolase family 38, N-terminal domain [IPR000602] 0.5907622739018058 0.3314009783594102 0.7403416259863029 1.0 0.8255339471696695 2 O00754 1 +Glycosyl hydrolase family 38, C-terminal [IPR011682] 0.5907622739018058 0.3314009783594102 0.7403416259863029 1.0 0.8255339471696695 2 O00754 1 +Glycoside hydrolase family 38, central domain [IPR015341] 0.5907622739018058 0.3314009783594102 0.7403416259863029 1.0 0.8255339471696695 2 O00754 1 +Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219] 0.4335596508244424 0.3270748534273021 0.7436112707888021 1.0 0.8282634467044916 5 Q92974,Q8NEN9,Q9H0H5,P05771 4 +TRASH domain [IPR011017] 0.4466709760827426 0.2546635288829356 0.7989829873798635 1.0 0.8808937487904372 4 Q9UBW7,Q5VZL5,Q9UHA3 3 +K Homology domain, type 1 [IPR004088] 0.3203409052022807 0.252589442751278 0.8005854889997792 1.0 0.8818811457194036 22 Q9NZI8,Q07666,O75525,Q96PU8,P51513,Q92667,P61978,Q92945,Q9NQT5,Q13868,Q15637,Q96I24 12 +EF-hand, Ca insensitive [IPR014837] 0.5579967689822186 0.2501896001868131 0.8024407274156238 1.0 0.8831449558456027 3 O43707,P12814 2 +Lamin tail domain [IPR001322] 0.55728799919922 0.2486715441899431 0.8036148619609251 1.0 0.8840472136651271 3 P20700 1 +ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100] 0.4379200563021249 0.2321943072233575 0.8163870991235236 1.0 0.8914161104215279 4 P06576 1 +ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194] 0.4379200563021249 0.2321943072233575 0.8163870991235236 1.0 0.8914161104215279 4 P06576 1 +Glycerophosphodiester phosphodiesterase domain [IPR030395] 0.5445736434108582 0.226946762610578 0.8204651392816438 1.0 0.8954770439666234 2 Q9NZC3 1 +Far upstream element-binding protein, C-terminal [IPR015096] 0.5436046511627934 0.2250344547445145 0.8219524705881907 1.0 0.8967080953727747 2 Q92945 1 +SPRY-associated [IPR006574] 0.545517697475481 0.2242316160729042 0.8225770836820572 1.0 0.8969973006060895 3 P14373 1 +EF hand associated, type-2 [IPR013567] 0.5326227390180944 0.2041870859042949 0.8382073027253745 1.0 0.909272704478178 2 Q8IXI2 1 +EF hand associated, type-1 [IPR013566] 0.5326227390180944 0.2041870859042949 0.8382073027253745 1.0 0.909272704478178 2 Q8IXI2 1 +MIRO domain [IPR020860] 0.5326227390180944 0.2041870859042949 0.8382073027253745 1.0 0.909272704478178 2 Q8IXI2 1 +MPN domain [IPR037518] 0.357759927246281 0.2016676335036374 0.8401765674043875 1.0 0.9106170876081436 8 O00303,P51665 2 +Rad60/SUMO-like domain [IPR022617] 0.5274547803617567 0.1949033304506786 0.8454686268721407 1.0 0.9155573889088504 2 Q8NCF5 1 +Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120] 0.5271317829457388 0.194334310804217 0.8459141215735626 1.0 0.915642400575288 2 Q9Y305 1 +Amine oxidase [IPR002937] 0.5276435781991259 0.189954473094315 0.849344806111689 1.0 0.918558860532581 3 P50336 1 +RING-type zinc-finger, LisH dimerisation motif [IPR027370] 0.5161498708010395 0.1757723148469936 0.8604728205240757 1.0 0.9279436896707424 2 O15344 1 +Ran binding domain [IPR000156] 0.5195476575121101 0.1755774352240458 0.8606259310212818 1.0 0.9279436896707424 3 P43487,P49792 2 +Zinc finger, MYM-type [IPR010507] 0.5151808785529701 0.1742075728310948 0.8617023342821319 1.0 0.9283019533825212 2 Q9UBW7 1 +Protein of unknown function DUF3504 [IPR021893] 0.5151808785529701 0.1742075728310948 0.8617023342821319 1.0 0.9283019533825212 2 Q9UBW7 1 +Survival motor neuron [IPR010304] 0.5122739018087926 0.1695842345707121 0.865337121940891 1.0 0.9318153298413996 2 Q16637 1 +Major sperm protein (MSP) domain [IPR000535] 0.5121163166397358 0.1630179757218372 0.8705042814144057 1.0 0.9365710142858742 3 Q8NHP6,Q9P0L0 2 +Heat shock protein Hsp90, N-terminal [IPR020575] 0.4065934065934085 0.1600420203286062 0.8728479733724555 1.0 0.9385809907119862 4 Q12931,P08238,P07900 3 +Zinc finger, UBP-type [IPR001607] 0.5054909560723618 0.1592085171252223 0.8735045937578025 1.0 0.9385848240420832 2 P45974 1 +Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040] 0.5019379844961244 0.1540026128515243 0.8776076754066191 1.0 0.9400640795250372 2 Q9Y678 1 +Coatomer subunit gamma, C-terminal [IPR032154] 0.5019379844961244 0.1540026128515243 0.8776076754066191 1.0 0.9400640795250372 2 Q9Y678 1 +3'-5' exonuclease domain [IPR002562] 0.5006459948320506 0.1521483671702101 0.8790699167528273 1.0 0.9400640795250372 2 Q9NVH0 1 +Extended synaptotagmin, C-terminal C2 domain [IPR037752] 0.4996770025839788 0.1507712219379929 0.8801561882847644 1.0 0.9400640795250372 2 Q9BSJ8 1 +Synaptotagmin, SMP domain [IPR039010] 0.4996770025839788 0.1507712219379929 0.8801561882847644 1.0 0.9400640795250372 2 Q9BSJ8 1 +Extended synaptotagmin, C2B domain [IPR037749] 0.4996770025839788 0.1507712219379929 0.8801561882847644 1.0 0.9400640795250372 2 Q9BSJ8 1 +Extended synaptotagmin, C2A domain [IPR037733] 0.4996770025839788 0.1507712219379929 0.8801561882847644 1.0 0.9400640795250372 2 Q9BSJ8 1 +Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468] 0.4998384491114678 0.1436089502205609 0.8858092726702678 1.0 0.944888471702573 3 Q8NEN9,Q9BSJ8 2 +Oxidoreductase FAD/NAD(P)-binding [IPR001433] 0.4970310483140976 0.139405618814462 0.889129632544648 1.0 0.9472153856528168 3 P16435 1 +FAD-binding domain, ferredoxin reductase-type [IPR017927] 0.4970310483140976 0.139405618814462 0.889129632544648 1.0 0.9472153856528168 3 P16435 1 +Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709] 0.4970310483140976 0.139405618814462 0.889129632544648 1.0 0.9472153856528168 3 P16435 1 +TOG domain [IPR034085] 0.3547865459249641 0.1388737914652675 0.8895498816368321 1.0 0.9472586234246247 6 O00410,Q14008,Q86Y56,Q8TEX9,Q7Z460 5 +CTP synthase, N-terminal [IPR017456] 0.4899870801033611 0.1376330486009716 0.8905304350736316 1.0 0.9474940023491304 2 P17812 1 +CTP synthase GATase domain [IPR033828] 0.4899870801033611 0.1376330486009716 0.8905304350736316 1.0 0.9474940023491304 2 P17812 1 +SMARCC, N-terminal [IPR032450] 0.4848191214470349 0.1310911947246585 0.895703166643919 1.0 0.9501613098539872 2 Q92922 1 +SMARCC, SWIRM-associated domain [IPR032448] 0.4848191214470349 0.1310911947246585 0.895703166643919 1.0 0.9501613098539872 2 Q92922 1 +SMARCC, C-terminal [IPR032451] 0.4848191214470349 0.1310911947246585 0.895703166643919 1.0 0.9501613098539872 2 Q92922 1 +ERM family, FERM domain C-lobe [IPR041789] 0.4894991922455421 0.1285585015360722 0.8977070047147289 1.0 0.951882268067679 3 P35241,P15311 2 +Pleckstrin homology domain 9 [IPR041681] 0.4783591731266261 0.1233603086082351 0.9018217860932856 1.0 0.9538132074195622 2 Q01082 1 +Pleckstrin homology domain, spectrin-type [IPR001605] 0.4783591731266261 0.1233603086082351 0.9018217860932856 1.0 0.9538132074195622 2 Q01082 1 +PSP, proline-rich [IPR006568] 0.4709302325581415 0.1150705529525597 0.9083892001699192 1.0 0.9599453851859164 2 Q6NZY4 1 +Fzo/mitofusin HR2 domain [IPR006884] 0.4693152454780356 0.1133518907971656 0.909751579387287 1.0 0.9606378536562044 2 Q8IWA4 1 +SWAP/Surp [IPR000061] 0.3450840879689454 0.1132724878739748 0.9098145283325094 1.0 0.9606378536562044 6 Q8IWZ8,Q8IWX8,Q8IX01,O15042,Q12872 5 +SWIRM domain [IPR007526] 0.3778280542986445 0.1058647947660646 0.9156896267639674 1.0 0.9643924097830724 4 Q8NB78,Q8TAQ2,Q92922 3 +Zinc finger, GATA-type [IPR000679] 0.3736263736263757 0.0989442118717331 0.9211825651138356 1.0 0.9697681434426244 4 Q8WXI9,O94776,Q13330 3 +Guanylate kinase-like domain [IPR008144] 0.3476178346162796 0.0967875913474145 0.922895078336641 1.0 0.9706776102601568 5 Q9NZW5 1 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.3476178346162796 0.0967875913474145 0.922895078336641 1.0 0.9706776102601568 5 Q9NZW5 1 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.463974151857831 0.0963864984280703 0.9232136148887182 1.0 0.9706776102601568 3 Q9BYT8,P52888 2 +Ancestral coatomer element 1, Sec16/Sec31 [IPR024298] 0.4447674418604621 0.0907217615326814 0.9277136787312472 1.0 0.9745876330250366 2 O94979 1 +Glutamine amidotransferase [IPR017926] 0.3603749191984507 0.0787687308119541 0.937216575941809 1.0 0.9792107860028532 4 P27708,P17812,Q9NRF8 3 +Protein of unknown function DUF3715 [IPR022188] 0.4257105943152409 0.0773166269315732 0.9383716641213408 1.0 0.980007242353598 2 Q9UK61 1 +EH domain [IPR000261] 0.3581124757595366 0.0755725957298929 0.9397591395373064 1.0 0.9805024537464876 4 Q9H223,Q96D71,Q9H4M9 3 +ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728] 0.4215116279069777 0.0748029992115571 0.9403714554801146 1.0 0.9805024537464876 2 Q14240 1 +Exoribonuclease, phosphorolytic domain 1 [IPR001247] 0.3278791701564231 0.0720150913437164 0.942589897879356 1.0 0.9805024537464876 6 Q96B26 1 +SGS domain [IPR007699] 0.4118217054263534 0.0695581564296187 0.9445453425629916 1.0 0.9807077110672758 2 Q9HB71 1 +Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187] 0.3911498708010401 0.0607045066611451 0.951594542506068 1.0 0.985975242339136 2 Q8WUM0 1 +DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263] 0.3779069767441838 0.0564707970197855 0.9549667589919276 1.0 0.9863104443427996 2 O15160 1 +DNA-directed RNA polymerase, insert domain [IPR011262] 0.3779069767441838 0.0564707970197855 0.9549667589919276 1.0 0.9863104443427996 2 O15160 1 +Methyltransferase type 11 [IPR013216] 0.4197092084006251 0.0563279233046132 0.9550805745620056 1.0 0.9863104443427996 3 Q6FI81,Q6UX53 2 +PTBP1, RNA recognition motif 2-like [IPR021790] 0.3410562735573433 0.0537576339892072 0.9571282638602808 1.0 0.9875004362388744 4 Q8WVV9 1 +Tudor domain [IPR002999] 0.3079266290074259 0.0523219174067371 0.9582721896685992 1.0 0.9879707079434524 9 Q15047 1 +ZU5 domain [IPR000906] 0.3439922480620134 0.0495121209390926 0.9605111779351356 1.0 0.9882045761265974 2 Q12955 1 +Ras GTPase-activating domain [IPR001936] 0.4090468497576759 0.0493484849855038 0.9606415811279614 1.0 0.9882045761265974 3 Q14C86,P46940 2 +Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333] 0.3217054263565829 0.0470978044769867 0.962435277171211 1.0 0.9885365950994788 2 Q9UHQ9 1 +MIT domain [IPR007330] 0.313630490956067 0.046509100310234 0.962904480938192 1.0 0.9885365950994788 2 Q8N0X7 1 +DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.3345184227537189 0.0464360054669443 0.96296273924096 1.0 0.9885365950994788 4 P42694,Q9HCE1,Q92900 3 +Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164] 0.2803617571059345 0.0451179817985552 0.964013268614374 1.0 0.9889856518062758 2 Q5JTZ9 1 +Thioredoxin domain [IPR013766] 0.282820542626974 0.0426794475923755 0.9659570630843096 1.0 0.989644327798179 25 O43819,Q8IXB1,Q9H1E5 3 +Death domain [IPR000488] 0.3660743134087237 0.0297150470173922 0.9762943114366474 1.0 0.997075033579384 3 Q12955,Q96FV9 2 +DNA2/NAM7 helicase, helicase domain [IPR041677] 0.3344103392568671 0.0219583874682552 0.9824811495165652 1.0 1.0 3 P42694,Q92900 2 +NIPSNAP [IPR012577] 0.3334410339256894 0.0217873933761458 0.9826175504298889 1.0 1.0 3 Q9BPW8,Q9UFN0 2 +Myosin tail [IPR002928] 0.3089202318550329 0.0184590399575817 0.9852726533719316 1.0 1.0 3 P35580 1 +Protein-tyrosine phosphatase, catalytic [IPR003595] 0.2694033333890204 0.0159299862492793 0.9872902474674234 1.0 1.0 3 P18031 1 +PDZ domain [IPR001478] 0.2758629674514232 0.0152275202640349 0.9878506662097628 1.0 1.0 18 Q9Y4G8,Q8WWI1,Q96RT1,Q9NZW5,O43464 5 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..773e91183dc5f014ee8422d801ec208585b9cae8 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase alpha 1 catalytic subunit, C-terminal [IPR039137]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA C-terminal domain [IPR032423]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADD domain [IPR025766]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARIP4, DEXH-box helicase domain [IPR044573]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ASCH domain [IPR007374]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "ATRX, ADD domain [IPR041430]", "AWS domain [IPR006560]", "Abl Interactor 1, SH3 domain [IPR035725]", "Abl-interactor, homeo-domain homologous domain [IPR012849]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acetyl-coenzyme A synthetase, N-terminal domain [IPR032387]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase [IPR006862]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Alpha/beta hydrolase fold-3 [IPR013094]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apolipoprotein B100 C-terminal [IPR022176]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAAT/Acyl-CoA thioester hydrolase C-terminal [IPR014940]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BARD1, Zinc finger, RING-type [IPR039503]", "BAT2, N-terminal [IPR009738]", "BCAS3 domain [IPR022175]", "BCL-6 corepressor, PCGF1 binding domain [IPR032365]", "BCL-6 corepressor, non-ankyrin-repeat domain [IPR031628]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BR140-related, PWWD domain [IPR035502]", "BRCA1, serine-rich domain [IPR025994]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BRPF2, PHD domain [IPR042009]", "BRPF2, ePHD domain [IPR042004]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-trefoil DNA-binding domain [IPR015350]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin/lipoyl attachment [IPR000089]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Bud22 domain [IPR015158]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBF1-interacting co-repressor CIR, N-terminal domain [IPR019339]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCDC93, coiled-coil domain [IPR019159]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-C, middle DNMT3B-binding domain [IPR028931]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COG complex component, COG2, C-terminal [IPR024603]", "COMM domain [IPR017920]", "COMMD1 N-terminal domain [IPR033776]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COQ9 [IPR013718]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRAL/TRIO, N-terminal domain [IPR011074]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centrosomal CEP44 domain [IPR029157]", "Chaperone DnaJ, C-terminal [IPR002939]", "Checkpoint kinase 1, catalytic domain [IPR034670]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain [IPR041715]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Classical Protein Kinase C alpha, catalytic domain [IPR034663]", "Classical protein kinase C beta, catalytic domain [IPR034664]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Conserved oligomeric Golgi complex, subunit 2, N-terminal [IPR024602]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-glucuronyl C5-epimerase, C-terminal [IPR010598]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEK, C-terminal [IPR014876]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIRP domain [IPR033471]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein Rad51-like, C-terminal [IPR013632]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA recombination and repair protein RecA-like, ATP-binding domain [IPR020588]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase 3-like, TOPRIM domain [IPR034144]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IA, DNA-binding domain [IPR003602]", "DNA topoisomerase, type IA, central [IPR013497]", "DNA topoisomerase, type IA, domain 2 [IPR003601]", "DNA topoisomerase, type IA, zn finger [IPR013498]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dehydrogenase, E1 component [IPR001017]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF1977, DnaJ-like [IPR015399]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3528, homeobox protein, eukaryotic [IPR021918]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF3699 [IPR022168]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4171 [IPR025228]", "Domain of unknown function DUF4195 [IPR025243]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4477 [IPR027951]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF4757 [IPR031865]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drought induced 19 protein type, zinc-binding domain [IPR008598]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EXOG, C-terminal [IPR041003]", "EXPERA domain [IPR033118]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enhancer of polycomb-like, N-terminal [IPR019542]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst complex component Sec3, C-terminal [IPR019160]", "Exocyst complex component Sec3, PIP2-binding N-terminal domain [IPR028258]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM192A/Fyv6, N-terminal [IPR019331]", "FAM3C (ILEI) domain [IPR039475]", "FAM69, protein-kinase domain [IPR022049]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FLYWCH-type zinc finger-containing protein, N-terminal [IPR029279]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferritin-like diiron domain [IPR009040]", "Ferritin/DPS protein domain [IPR008331]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Ferrodoxin-fold anticodon-binding domain [IPR005121]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Follistatin-like, N-terminal [IPR003645]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCF, C-terminal [IPR022783]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPI ethanolamine phosphate transferase 2, C-terminal [IPR045687]", "GPI ethanolamine phosphate transferase 2, N-terminal [IPR037674]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "Gid-type RING finger domain [IPR044063]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucose-methanol-choline oxidoreductase, C-terminal [IPR007867]", "Glucose-methanol-choline oxidoreductase, N-terminal [IPR000172]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyl transferase, family 28, C-terminal [IPR007235]", "Glycosyltransferase 2-like [IPR001173]", "Glycosyltransferase subfamily 4-like, N-terminal domain [IPR028098]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Groucho/TLE, N-terminal Q-rich domain [IPR005617]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Heavy metal-associated domain, HMA [IPR006121]", "Heavy metal-associated domain, copper ion-binding [IPR006122]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "HhH-GPD domain [IPR003265]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histidyl-anticodon-binding [IPR033656]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homeobox domain, metazoa [IPR020479]", "Homocysteine-binding domain [IPR003726]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "Hpc2-related domain [IPR014840]", "HuR, RNA recognition motif 2 [IPR034996]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I/LWEQ domain [IPR002558]", "IF2a, S1-like domain [IPR044126]", "IFT81, calponin homology domain [IPR041146]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Inhibitor of growth protein, N-terminal histone-binding [IPR024610]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrator complex subunit 5, C-terminal [IPR029444]", "Integrator complex subunit 5, N-terminal [IPR029445]", "Integrin alpha-2 [IPR013649]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KAP family P-loop domain [IPR011646]", "KASH domain [IPR012315]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KMT2B, ePHD domain [IPR041959]", "KOW [IPR005824]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore assembly subunit CENP-C, N-terminal domain [IPR028052]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIN-9, C-terminal [IPR045831]", "LIS1 homology motif [IPR006594]", "LKB1 serine/threonine kinase interacting protein 1, N-terminal [IPR031782]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "LYRM2, LYR domain [IPR045293]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipid desaturase domain [IPR019547]", "Lipid transport, open beta-sheet [IPR009454]", "Little elongation complex subunit 2 , C-terminal [IPR019535]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lunapark domain [IPR019273]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "MABP domain [IPR023341]", "MAGE homology domain [IPR002190]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MYST, zinc finger domain [IPR040706]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Mediator complex, subunit Med12 [IPR019035]", "Mediator complex, subunit Med12, LCEWAV-domain [IPR021990]", "Mediator complex, subunit Med12, catenin-binding [IPR021989]", "Mediator complex, subunit Med25, NR box [IPR021406]", "Mediator complex, subunit Med25, PTOV domain [IPR021394]", "Mediator complex, subunit Med25, synapsin 1 [IPR021397]", "Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain [IPR021419]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "MgsA AAA+ ATPase C-terminal [IPR021886]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Mif2/CENP-C cupin domain [IPR025974]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondria fission protein Fis1, cytosolic domain [IPR033745]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdenum cofactor synthesis C-terminal [IPR010505]", "Molybdopterin cofactor biosynthesis C (MoaC) domain [IPR002820]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Myb domain [IPR017930]", "Myc-type, basic helix-loop-helix (bHLH) domain [IPR011598]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myotubularin-like phosphatase domain [IPR010569]", "Myotubularin-related 12-like C-terminal domain [IPR022587]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-CoR, GPS2-interacting domain [IPR031557]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-acetyltransferase ESCO, acetyl-transferase domain [IPR028009]", "N-acetyltransferase ESCO, zinc-finger [IPR028005]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase intermediate-associated protein 30 [IPR013857]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NCBP2, RNA recognition motif [IPR034148]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, C-terminal [IPR001075]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NP60, PWWP domain [IPR035501]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nischarin, PX domain [IPR037904]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear hormone receptor, ligand-binding domain [IPR000536]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear protein 96 [IPR021967]", "Nuclear speckle splicing regulatory protein 1, N-terminal [IPR018612]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar 27S pre-rRNA processing, Urb2/Npa2, C-terminal [IPR018849]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PB1 domain [IPR000270]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K p85 subunit, C-terminal SH2 domain [IPR035020]", "PI3K p85 subunit, N-terminal SH2 domain [IPR035022]", "PI3K regulatory subunit p85-related , inter-SH2 domain [IPR032498]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PINIT domain [IPR023321]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLD-like domain [IPR032803]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKAA1, UBA-like autoinhibitory domain [IPR028797]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palmitoyltransferase, DHHC domain [IPR001594]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Patatin-like phospholipase domain [IPR002641]", "Patatin-like phospholipase domain containing protein 8-like [IPR045217]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 3-kinase regulatory subunit beta, SH3 domain [IPR035586]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Plus-3 domain [IPR004343]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Pop1, N-terminal [IPR009723]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein OS9-like domain [IPR012913]", "Protein RED, C-terminal [IPR012492]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein furry, C-terminal [IPR045842]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAD51 interacting motif [IPR031419]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM40, RNA recognition motif 1 [IPR034147]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM8, RNA recognition motif [IPR033744]", "RBP-J/Cbf11/Cbf12, DNA binding [IPR015351]", "RBP-Jkappa, IPT domain [IPR038007]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING finger and SPRY domain-containing protein 1, SPRY domain [IPR035774]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 2-O ribose methyltransferase, substrate binding [IPR013123]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II elongation factor ELL, N-terminal [IPR019464]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RQC domain [IPR018982]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rad18, zinc finger UBZ4-type [IPR006642]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad51/DMC1/RadA [IPR033925]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap1 Myb domain [IPR015010]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rhodanese-like domain [IPR001763]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal RNA-processing protein 7, C-terminal domain [IPR024326]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ricin B, lectin domain [IPR000772]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rrp7, RRM-like N-terminal domain [IPR040447]", "Rrp7A, RNA recognition motif [IPR034890]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SCAF8, RNA recognition motif [IPR034370]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD2/Set2, SET domain [IPR044437]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGF29 tudor-like domain [IPR010750]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMYD3, SET domain [IPR044420]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX2, PX domain [IPR037918]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPOP, C-terminal BACK domain [IPR034089]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAR protein, homodimerisation region [IPR032377]", "STARD11, START domain [IPR041952]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Scaffold protein Nfu/NifU, N-terminal [IPR014824]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine proteases, trypsin domain [IPR001254]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set2 Rpb1 interacting domain [IPR013257]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein LSm5 [IPR033871]", "Sm-like protein Lsm3 [IPR034105]", "Sm-like protein Lsm4 [IPR034101]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromal interaction molecule 1, SAM domain [IPR037609]", "Stromal interaction molecule, Orai1-activating region [IPR032393]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfatase-modifying factor enzyme [IPR005532]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA element modulatory factor 1, TATA binding [IPR022091]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG, PB1 domain [IPR034857]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TGS [IPR004095]", "THAP-type zinc finger [IPR006612]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRC8 N-terminal domain [IPR025754]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRIM27, PRY/SPRY domain [IPR035791]", "TRIM4, PRY/SPRY domain [IPR035829]", "TROVE domain [IPR008858]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Target SNARE coiled-coil homology domain [IPR000727]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere repeat-binding factor, dimerisation domain [IPR013867]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Telomeric repeat-binding factor 2, Rap1-binding domain [IPR031902]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine synthase, N-terminal [IPR029144]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor 20, ePHD domain [IPR041972]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Lyn, SH2 domain [IPR035852]", "Tyrosine-protein kinase Lyn, SH3 domain [IPR035748]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC2, UBA domain [IPR041928]", "UBX domain [IPR001012]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UMA domain [IPR023340]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "UVR domain [IPR001943]", "Ubinuclein middle domain [IPR026947]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VIP36, lectin domain [IPR035664]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vitellinogen, open beta-sheet [IPR015255]", "Vitellogenin, N-terminal [IPR001747]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WRNIP1, ubiquitin-binding domain [IPR040539]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C2HC5-type [IPR009349]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FCS-type [IPR012313]", "Zinc finger, FLYWCH-type [IPR007588]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc finger, nuclear hormone receptor-type [IPR001628]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cDENN domain [IPR001194]", "dDENN domain [IPR005112]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA splicing factor Cwf21 domain [IPR013170]", "p21 activated kinase binding domain [IPR033923]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNase Z endonuclease [IPR027794]", "uDENN domain [IPR005113]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTN1", "ACTN4", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "APLP2", "APMAP", "APOB", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL2", "ARL3", "ARL8A", "ARL8B", "ARMC10", "ARMCX3", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATP7A", "ATP7B", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAP18", "BARD1", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS3", "BCKDHA", "BCKDHB", "BCOR", "BCS1L", "BIRC6", "BLM", "BLVRA", "BMI1", "BMS1", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "C1orf35", "C2CD5", "C3orf58", "CACYBP", "CAD", "CALU", "CAMK2G", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASK", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC93", "CCNB1", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC34", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPV", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHORDC1", "CHP1", "CHRAC1", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLIC1", "CLPB", "CLPX", "CLTC", "CLUH", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNPY2", "COA3", "COG2", "COIL", "COL4A3BP", "COLEC12", "COMMD1", "COMMD10", "COMMD5", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC25", "CWF19L1", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCTN1", "DCUN1D5", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "EARS2", "ECE1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMC8", "EMD", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESCO2", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM192A", "FAM208A", "FAM208B", "FAM3C", "FAM49B", "FAM8A1", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FBXO22", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDE1", "GDPD1", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGB1", "GORASP2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPI", "GPR89B", "GPS1", "GPT2", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F2", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HELLS", "HELZ", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGXB4", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA4", "HSPA4L", "HSPB1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "IARS", "IARS2", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS11", "INTS14", "INTS3", "INTS5", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "IVD", "IWS1", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1147", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LETMD1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LRRC8C", "LSM12", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "M6PR", "MACF1", "MAEA", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBD3", "MBNL1", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED25", "MEPCE", "METTL7B", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD8", "MGME1", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPHOSPH8", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRM3", "MRPL11", "MRPL12", "MRPL15", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCBP1", "NCBP2", "NCEH1", "NCKIPSD", "NCL", "NCLN", "NCOR1", "NCSTN", "NDUFA10", "NDUFA2", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFE", "NENF", "NEPRO", "NES", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NTHL1", "NTPCR", "NUB1", "NUBP1", "NUCB1", "NUCB2", "NUDC", "NUDT1", "NUDT12", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NVL", "NXF1", "NXN", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAXBP1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDZD8", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF3", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP4R1", "PPP5C", "PPP6C", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2B", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPMT1", "PTPN1", "PTPN9", "PUF60", "PUM3", "PUS1", "PWP2", "PWWP2A", "PYCR1", "PYCR2", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RAC1", "RACGAP1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAI1", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOX1", "RIPK1", "RMND1", "RNASEH2A", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPEP", "RNPS1", "RP2", "RPA1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRP12", "RRP7A", "RSF1", "RSL24D1", "RSPRY1", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SC5D", "SCAF11", "SCAF8", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A2", "SLC27A4", "SLC2A1", "SLC37A4", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMU1", "SMYD3", "SNAP23", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPC25", "SPECC1L", "SPEN", "SPNS1", "SPOP", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK11IP", "STK26", "STOM", "STOML2", "STRBP", "STRN", "STRN4", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THNSL1", "THOC1", "THOC2", "THOC3", "THOP1", "THYN1", "TIAL1", "TIMELESS", "TIMM10", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TKT", "TLCD1", "TLE3", "TLN1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED8", "TMED9", "TMEM201", "TMEM205", "TMEM97", "TMF1", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOX4", "TP53", "TP53BP1", "TPBG", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMT1L", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TST", "TTC4", "TTF1", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBFD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCRC1", "UQCRC2", "URB1", "URB2", "UROD", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS16", "VPS29", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WASHC4", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WRNIP1", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YBX1", "YBX3", "YES1", "YIPF4", "YKT6", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZCCHC17", "ZCCHC3", "ZCCHC8", "ZDHHC20", "ZEB2", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF148", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF644", "ZPR1", "ZRANB2", "ZYX"], "leading_proteins": ["AARS2", "ABCB1", "ABCB7", "ABCC1", "ABCD4", "ACBD3", "ACOT9", "ACTN1", "ACTN4", "ADD3", "AIFM1", "AKAP1", "AKT2", "ALG1", "ALYREF", "ANK3", "ANKLE2", "ARHGEF2", "ARMC10", "ATAD3B", "ATP13A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5B", "ATP7A", "ATP7B", "BAG3", "BAG5", "BSG", "CACYBP", "CAD", "CBX1", "CD47", "CDKAL1", "CERS2", "CETN2", "CHERP", "CIAPIN1", "CKAP5", "CLASP1", "CLCN3", "CNNM3", "CNNM4", "COLEC12", "COPG1", "CPT2", "CTPS1", "CTPS2", "CYB5B", "CYB5D2", "CYB5R1", "DHCR24", "DNAAF5", "DNAJC10", "DNM1L", "DNM2", "DPM1", "EHD1", "EHD4", "EIF3F", "EIF4A2", "EMD", "EPHA7", "ERAP1", "ERBIN", "ERGIC2", "ERGIC3", "ERMP1", "ESYT1", "EXD2", "EXOSC2", "EXOSC3", "EXOSC8", "EZR", "FAM208A", "FAM49B", "FARP1", "FKBP14", "FKBP9", "FLOT1", "FLOT2", "FOXRED1", "FUBP3", "GAPVD1", "GATAD2B", "GDE1", "GINS3", "GPAM", "HELZ", "HINT3", "HLA-C", "HNRNPAB", "HNRNPF", "HNRNPH1", "HNRNPK", "HNRNPLL", "HSP90AA1", "HSP90AB1", "HTRA2", "IGF2BP1", "IPO4", "IPO5", "IQGAP1", "KDM1B", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA1147", "L2HGDH", "LEMD3", "LETM1", "LMNB1", "LMO7", "LNPEP", "LSM3", "LSM5", "MAN2B1", "METTL7B", "MFN1", "MFSD8", "MID1", "MOSPD2", "MOV10", "MPP6", "MPRIP", "MRC2", "MTA1", "MTA2", "MTMR12", "MTX1", "MYH10", "NCAM1", "NEFL", "NENF", "NFATC2IP", "NIPSNAP1", "NIPSNAP3A", "NLN", "NONO", "NOVA1", "NPEPPS", "NUCB1", "NUCB2", "NUP133", "OPA1", "OSBPL6", "PABPC1", "PABPC4", "PCYOX1", "PDZD8", "PHB", "PHB2", "PIK3R2", "PMPCA", "PNPLA6", "POLE3", "POLE4", "POLR1C", "POR", "PPAT", "PPOX", "PRKCB", "PRKRA", "PSMD7", "PSME2", "PTBP2", "PTGES2", "PTPN1", "QKI", "RACGAP1", "RANBP1", "RANBP2", "RAPGEF2", "RARS", "RBM10", "RBM6", "RBMXL1", "RCN2", "RDX", "REPS1", "RHOT1", "RSL24D1", "RTN2", "RTN3", "RTN4", "SCO2", "SDF4", "SEC22B", "SEC31A", "SEL1L", "SETDB1", "SF1", "SFPQ", "SFSWAP", "SLC12A9", "SLC16A1", "SLC25A12", "SLC25A13", "SMARCC1", "SMARCC2", "SMN1*", "SPART", "SPNS1", "SPOP", "SPTBN1", "STAU2", "STIM1", "STOM", "STOML2", "STX10", "STX3", "STX6", "STX7", "STX8", "SUGP1", "SUGP2", "SYNCRIP", "SYNGR2", "TAF15", "TAP1", "THOC1", "THOP1", "TLCD1", "TMED2", "TMED7", "TMPO", "TMX4", "TPBG", "TRAP1", "TRIM27", "TUBB", "TUBB2B", "U2SURP", "UBXN4", "UNC119B", "UPF1", "UQCRC2", "USP5", "VAMP7", "VAPA", "VIM", "YBX3", "ZADH2", "ZCCHC8", "ZMYM2", "ZMYM4", "ZNF326"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..cebd2625a48b1bd59d52168d8236a1cb2344bd59 --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Proteasome B-type subunit [IPR023333]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..57626135115d23174e818c6ddb4c7760bc531948 --- /dev/null +++ b/interpro_family/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:af0df748a71602514cdcb4575c65dcbd91235beda01b55efc1d2a6ccd593e23e +size 185797 diff --git a/interpro_family/advanced/plot_1.png b/interpro_family/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..4b645b056e5c40a8d120b8dd570715773b003a65 --- /dev/null +++ b/interpro_family/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:31c211526e30e0acf40854917eb74d5af92563f7e17d4f08bedc44a3136119d0 +size 180737 diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..f4022ddbcd3b7d3ac3e4b51e26e58ee6da009c09 --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Proteasome B-type subunit [IPR023333]", "2": "P-type ATPase [IPR001757]", "3": "Syntaxin [IPR045242]", "4": "Proteasome, subunit alpha/beta [IPR001353]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..06cfdc7082ec4843972cdfd13b35bc927b5277c8 --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a0699d0e91299357f4891aa7470c83eda902b2e9688473598553237999221380 +size 136888 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..89955f48f528fa282f6f91abfad436cc41f85fb8 --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:65380bb6c539e0a5be91e477393b28898a37caf84f1ebc790763b528687a859e +size 136829 diff --git a/interpro_family/basic/plot_2.png b/interpro_family/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..d9ea0dfdad4a6ff6d18b0e45829fd175736f5fc3 --- /dev/null +++ b/interpro_family/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6a58bcc7eb209a473002ad138345a34804edbabd5f024305a035eabc877b3456 +size 127075 diff --git a/interpro_family/basic/plot_3.png b/interpro_family/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..6dacdac619fee26cead257e9aa181b3de9523b5c --- /dev/null +++ b/interpro_family/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:98ebfc22e0dda3777fb2fab9775c5f0eb008206a3b8b4f202cb0a1b25029c2f4 +size 126308 diff --git a/interpro_family/basic/plot_4.png b/interpro_family/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..619487baeb18b27a6f771b805753d82381d3dc2b --- /dev/null +++ b/interpro_family/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ffe0fc95a779ccf9fae2ca99c2c725c61b911a047aa6b688d13f72dfef1f34d0 +size 143887 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d32dfde6c2f6938a27ec4d1b0c483868d4874d5f --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:38ffd645397b232385f2a86c526c4564e394a6ce62301bab9091d3be2729f4bc +size 421267 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9ce039b44371bb17728c1771577839ad3ef405da --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier protein [IPR002067] 8 15 2.545667059939273 0.0109069160395178 5.686893203883495 11.07766990291262 0.8032246115450145 0.31892620527414 3.2338505495684404 1.5403272908315857 1.3918146051602212 0.3274613788058813 0.0459284510874455 1.0 1.0 0.01180448121602 2.7180346417726147e-05 +Glutathione Transferase family [IPR040079] 2 9 2.140630489401396 0.0323038480374264 2.6650485436893203 9.45388349514563 0.453215617797485 0.4615521029697171 1.6850115229858122 1.256172900264393 0.947748980990547 0.2879961408071128 0.023528073884608 0.0652597674910206 0.0078714328443906 0.0041946485896371 0.0277461310389573 +Proteasome B-type subunit [IPR023333] 5 7 1.962321188259692 0.0497251018913174 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 0.0098489116445482 1.0 0.0841007109914387 0.0188064524051028 2.8311070051942505e-05 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..792b7628cc8e44896a1a466800dad61d0e2d3fe8 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 2391, + "title": "Average number of proteins per term", + "value": 1.288582183186951 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ca2b2ee0df65d521e014ae7f469058b779e7ebe1 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..01166b5654c0d68aa266716638e1c85e9bcce2ab --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,119 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial carrier protein [IPR002067] 0.7048523510607422 2.5456670599392734 0.0109069160395178 0.9999999999959068 0.0660718482698809 15 Q86VD7,Q8TBP6,Q9BQT8,O75746,Q96H78,P16260,O43808,Q9UJS0 8 +Glutathione Transferase family [IPR040079] 0.7571966758116859 2.140630489401396 0.0323038480374264 1.0 0.108086474593305 9 Q9H7Z7,Q13505 2 +Proteasome B-type subunit [IPR023333] 0.7737374506279218 1.962321188259692 0.0497251018913174 1.0 0.1407014421563786 7 P28074,P28072,P49721,P28070,P20618 5 +Major facilitator superfamily [IPR011701] 0.7883153984541187 1.9392226127320236 0.0524742372857793 1.0 0.1458905829654633 6 P53985,Q8NHS3,Q9H2V7 3 +P-type ATPase [IPR001757] 0.7049311463738145 1.894560041419152 0.0581507128361031 1.0 0.1563985988651549 9 Q04656,P16615,P98194,Q9HD20,P35670,P20020,P23634 7 +Syntaxin [IPR045242] 0.7538438924386892 1.8753366365383388 0.0607464261966637 1.0 0.1613830055958032 7 O43752,O15400,Q13277,O60499,Q9UNK0 5 +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.997093023255814 1.8166872295213845 0.0692650182518295 1.0 0.1754515887818567 2 Q99595 1 +Eukaryotic porin/Tom40 [IPR027246] 0.8580004960648473 1.7872516714487563 0.0738968212940629 1.0 0.1833757212397302 4 P21796 1 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.9893410852713168 1.785999205750507 0.0740993867366608 1.0 0.1835065774232669 2 Q5VW38 1 +Palmitoyl protein thioesterase [IPR002472] 0.9883720930232548 1.782160420024741 0.0747230751940277 1.0 0.1841510160159876 2 Q9UMR5 1 +CD36 family [IPR002159] 0.9877260981912132 1.779600896627623 0.0751412993836888 1.0 0.184420714370685 2 Q14108 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.9874031007751932 1.7783210357289994 0.0753511433870559 1.0 0.184420714370685 2 Q9Y487 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.9874031007751932 1.7783210357289994 0.0753511433870559 1.0 0.184420714370685 2 Q9Y487 1 +ER lumen protein retaining receptor [IPR000133] 0.9819121447028416 1.7565535148296365 0.0789939422582324 1.0 0.1907823393327613 2 P24390 1 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.7786366931692127 1.7353059191754268 0.0826866338861762 1.0 0.196260364302539 5 P55786,Q9UIQ6,Q9NZ08 3 +Haem oxygenase-like [IPR016053] 0.9757751937984468 1.732204000597203 0.0832372470036126 1.0 0.1966603335826461 2 P30519 1 +Haem oxygenase [IPR002051] 0.9757751937984468 1.732204000597203 0.0832372470036126 1.0 0.1966603335826461 2 P30519 1 +Mpv17/PMP22 [IPR007248] 0.9638242894056812 1.684728799104052 0.0920409075020072 1.0 0.2095090089149576 2 Q567V2 1 +Type 1 protein exporter [IPR039421] 0.7170442085334139 1.6316083595917583 0.102762016061491 1.0 0.2264552814774424 6 Q03518,P08183,O75027 3 +Histidine phosphatase superfamily, clade-2 [IPR000560] 0.9628432956381244 1.5746526214515415 0.1153366494677965 1.0 0.2436120825398178 3 Q9NPH0,Q9UNW1 2 +Prenylcysteine oxidase [IPR017046] 0.9360465116279038 1.5741551213958738 0.1154515918014289 1.0 0.2436120825398178 2 Q9UHG3 1 +Transmembrane emp24 domain-containing protein [IPR015720] 0.6957397299062857 1.538013579333686 0.1240452945822134 1.0 0.2556830166776486 6 Q15363,Q9Y3B3 2 +Tetraspanin, animals [IPR000301] 0.9192506459948232 1.5072088176986629 0.1317571407881947 1.0 0.2672021404788581 2 O60637 1 +Tetraspanin/Peripherin [IPR018499] 0.9192506459948232 1.5072088176986629 0.1317571407881947 1.0 0.2672021404788581 2 O60637 1 +Cytochrome P450 [IPR001128] 0.9111757105943072 1.4750181552949146 0.1402076624473887 1.0 0.2772841364033965 2 Q16850 1 +Aminopeptidase N-type [IPR034016] 0.9350565428109848 1.473512461634797 0.1406129061548973 1.0 0.2776263076931127 3 P55786,Q9UIQ6 2 +Nucleobindin [IPR040250] 0.9056847545219556 1.453131132825368 0.1461873485135505 1.0 0.2846367673419376 2 P80303 1 +Stomatin/HflK/HflC family [IPR001972] 0.9034237726098134 1.4441200305565278 0.1487052145416612 1.0 0.2883502166372966 2 P27105 1 +Acyltransferase ChoActase/COT/CPT [IPR000542] 0.8879198966408282 1.3823627897839132 0.1668603353918549 1.0 0.3129122054289609 2 P23786 1 +Yif1 family [IPR005578] 0.8853359173126538 1.3720777774508852 0.1700392266249843 1.0 0.3170137979679269 2 Q5BJH7 1 +Mitochondrial carrier UCP-like [IPR002030] 0.8833979328165305 1.364365921751717 0.1724524277633907 1.0 0.3196385695986568 2 Q9UBX3 1 +Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019] 0.7412960776561075 1.3244413933459098 0.185356494980474 1.0 0.3337254363692118 4 Q14344,P04899 2 +Porin, eukaryotic type [IPR001925] 0.892015424142562 1.3166328606722342 0.187961718442404 1.0 0.3363019307699408 3 P21796 1 +Tricarboxylate/iron carrier [IPR004686] 0.8898864242673241 1.3088775863025046 0.1905758200822771 1.0 0.3382826917718816 3 Q6P4A7 1 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.8688630490956046 1.3065909341816986 0.1913516772377494 1.0 0.3388014050254228 2 O43819 1 +Copper chaperone SCO1/SenC [IPR003782] 0.8688630490956046 1.3065909341816986 0.1913516772377494 1.0 0.3388014050254228 2 O43819 1 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.8601421188630448 1.2719941611518686 0.2033751938393333 1.0 0.3516052700432726 2 Q5T9A4 1 +SCAMP [IPR007273] 0.7070592868577491 1.1873884928568863 0.2350744168172844 1.0 0.387879738959922 4 O15127,O15126 2 +Beta tubulin [IPR002453] 0.8436187399030685 1.1408653522521912 0.2539259597079577 1.0 0.4062314975019192 3 P07437,Q9BVA1 2 +Tubulin [IPR000217] 0.8436187399030685 1.1408653522521912 0.2539259597079577 1.0 0.4062314975019192 3 P07437,Q9BVA1 2 +HnRNP R/Q splicing factor [IPR006535] 0.8255813953488373 1.1356577807837756 0.2560998164765062 1.0 0.4084954377553879 2 O60506 1 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.8400646203554267 1.128023075105343 0.25931017410517 1.0 0.4111476301627728 3 Q9HB40,Q9H3G5 2 +Sulfotransferase [IPR005331] 0.8217054263565736 1.1204685030803434 0.2625141673601789 1.0 0.4134857537273965 2 Q8NCH0 1 +KH domain-containing BBP-like [IPR045071] 0.6900452488687794 1.1193924423794628 0.2629727537445065 1.0 0.4139194648549755 4 O75525,Q15637,Q96PU8 3 +P-type ATPase, subfamily IIB [IPR006408] 0.8149224806201565 1.0939485304493797 0.2739775524452521 1.0 0.4234520542318021 2 P20020 1 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.8232633279483152 1.0674994117636378 0.285746379130372 1.0 0.4346180613872262 3 P28074,P28072 2 +Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699] 0.8062015503875963 1.059976842419869 0.2891551347496064 1.0 0.4384083241511153 2 Q9NQT5 1 +TB2/DP1/HVA22-related protein [IPR004345] 0.6702964783767184 1.040731302940238 0.2980002708970257 1.0 0.4475619646449676 4 Q9BRK0,Q00765 2 +Molecular chaperone regulator BAG [IPR039773] 0.8080775444264999 1.0131123824863668 0.3110064844266489 1.0 0.4598741522969187 3 O95817,Q9UL15 2 +Prenylated rab acceptor PRA1 [IPR004895] 0.8003231017770713 0.9854800907059632 0.3243883061561394 1.0 0.4709243715964356 3 Q9UI14,O75915 2 +E3 ubiquitin-protein ligase, SMURF1 type [IPR024928] 0.7748708010335847 0.939359308084304 0.3475462978057528 1.0 0.4896777831782882 2 Q96PU5 1 +P-type ATPase, subfamily IB [IPR027256] 0.7729328165374701 0.931985043672298 0.3513442548847139 1.0 0.492848115836044 2 P35670 1 +Endoplasmic reticulum vesicle transporter [IPR045888] 0.7754442649434763 0.8976089101081696 0.3693940871273908 1.0 0.5093548225614715 3 Q96RQ1,Q9Y282 2 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.7590439276485608 0.879486520424106 0.3791375386317708 1.0 0.5183655756483353 2 O96005 1 +Cleft lip and palate transmembrane 1 [IPR008429] 0.7590439276485608 0.879486520424106 0.3791375386317708 1.0 0.5183655756483353 2 O96005 1 +Ancient conserved domain protein family [IPR045095] 0.7587209302325575 0.8782733634943279 0.3797953873089978 1.0 0.5186795344668639 2 Q6P4Q7 1 +TAF15/EWS/TLS family [IPR034870] 0.7571059431524565 0.8722131447541861 0.3830921098566242 1.0 0.5204393378790844 2 Q92804 1 +Integral membrane protein EMC3/TMCO1-like [IPR002809] 0.7532299741601881 0.8577072108305976 0.3910541573256383 1.0 0.5265814887338611 2 Q9P0I2 1 +Prefoldin beta-like [IPR002777] 0.751937984496119 0.8528842810809947 0.3937234794546336 1.0 0.5285423795498506 2 O60925 1 +Proteasome, subunit alpha/beta [IPR001353] 0.4365581140641519 0.838833594503862 0.4015626959836353 1.0 0.5351930914698284 14 P28074,P28072,P49721,P28070,P20618 5 +HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380] 0.7528271405492933 0.8190071586094899 0.4127823293255668 1.0 0.5458863658282246 3 Q5TFE4,P49902 2 +Protein-tyrosine phosphatase-like, PTPLA [IPR007482] 0.7416020671834604 0.8145352712022522 0.4153383747792696 1.0 0.547671589069914 2 Q6Y1H2 1 +A-kinase anchoring protein 95 (AKAP95) [IPR007071] 0.7457033052923724 0.7945547304270176 0.4268725604158545 1.0 0.5577675326403265 3 Q5BKZ1 1 +Arginine-tRNA ligase [IPR001278] 0.7238372093023263 0.7496916944664244 0.4534404108937038 1.0 0.5810160891998102 2 P54136 1 +G-protein alpha subunit, group I [IPR001408] 0.7322378056255163 0.7487936600981637 0.4539815815512651 1.0 0.5810867031526097 3 P04899 1 +Graves disease carrier protein [IPR002167] 0.7290286782882138 0.7379831040795353 0.4605247164403527 1.0 0.5866353740057983 3 Q86VD7 1 +Flotillin family [IPR027705] 0.7154392764857754 0.7195631794092008 0.4717939893874201 1.0 0.5930898880077669 2 O75955 1 +Tropomyosin [IPR000533] 0.7232230523817791 0.7185254262268008 0.4724333761442487 1.0 0.5930898880077669 3 P67936 1 +E3 ubiquitin ligase Bre1 [IPR013956] 0.7151162790697692 0.7184116468400792 0.47250350760541 1.0 0.5930898880077669 2 Q5VTR2 1 +Dynamin [IPR022812] 0.7186814870043525 0.7033973773433715 0.4818081405066157 1.0 0.6003041824901473 3 P50570 1 +Prohibitin [IPR000163] 0.7041343669250638 0.6795973779104385 0.4967594303979048 1.0 0.6116126663652885 2 P35232 1 +Myotubularin family [IPR030564] 0.6912144702842262 0.6348307134611986 0.5255388296307872 1.0 0.6303370146554937 2 Q9C0I1 1 +SLC12A transporter family [IPR004842] 0.6873385012919848 0.6216039295189206 0.5342023365230297 1.0 0.6367853723933674 2 Q9BXP2 1 +Vacuolar protein sorting-associated protein 33 [IPR027121] 0.6715116279069777 0.5686498171910445 0.5695938099264728 1.0 0.6605247288822315 2 Q9H267 1 +Peptidase C13, legumain [IPR001096] 0.6673126614986946 0.5549018592238025 0.5789617901280499 1.0 0.6661682580347292 2 Q92643 1 +Synaptobrevin [IPR001388] 0.6624677002583849 0.5392048178668092 0.5897455363564048 1.0 0.670828533505311 2 O75396 1 +Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515] 0.6592377260981932 0.528841623215299 0.5969153208822118 1.0 0.6748106535363444 2 P11940 1 +ADP-ribosylation factor-like protein 2/3 [IPR044612] 0.6511627906976656 0.5033013661195839 0.614752406114043 1.0 0.684936161704882 2 P36404 1 +Sec1-like protein [IPR001619] 0.4824697490180321 0.4996838826814576 0.617297682934262 1.0 0.6861732960928966 5 Q9NRW7 1 +Proteasome activator PA28 [IPR009077] 0.6445912186715317 0.4711836771875148 0.6375095740198997 1.0 0.6976134514789841 3 Q9UL46 1 +CPSF6/7 family [IPR034772] 0.6085271317829496 0.3781419301139189 0.7053251610894946 1.0 0.7446002228644992 2 Q8N684 1 +Importin beta family [IPR040122] 0.4824622739545038 0.3560417423779355 0.7218093048444629 1.0 0.7586136474211477 4 Q92973,O00410 2 +TMEM70/TMEM186/TMEM223 protein family [IPR045325] 0.5878552971576283 0.3240841812604947 0.7458743027054044 1.0 0.7804750362225916 2 Q9BUB7 1 +Initiation factor 2B-related [IPR000649] 0.5857835218093667 0.3137029463475992 0.7537466627977762 1.0 0.7876784400128859 3 Q9UI10,Q9BV20 2 +Cell-cycle alteration and expression-elevated protein in tumour [IPR032337] 0.5822294022617037 0.3051555554630352 0.7602476805425196 1.0 0.7941250345902858 3 Q96P16,Q5VT52 2 +Structural maintenance of chromosomes protein [IPR024704] 0.4560439560439578 0.2797831259659106 0.7796438984273142 1.0 0.8122564536556462 4 Q14683,Q9NTJ3,Q9UQE7 3 +Tumour protein D52 [IPR007327] 0.564922480620162 0.2697994029102235 0.7873145822029648 1.0 0.8191771827882023 2 P55327 1 +Nucleosome assembly protein (NAP) [IPR002164] 0.5501759833381913 0.2337293807203915 0.8151950769089915 1.0 0.8445110177163773 3 P55209 1 +THRAP3/BCLAF1 family [IPR029199] 0.5406976744186103 0.2193682413515719 0.8263632072492255 1.0 0.8545996663204577 2 Q9NYF8 1 +Mitochondrial Rho GTPase [IPR021181] 0.5326227390180944 0.2041870859042949 0.8382073027253745 1.0 0.865725123462795 2 Q8IXI2 1 +Ran binding protein RanBP1-like [IPR045255] 0.5195476575121101 0.1755774352240458 0.8606259310212818 1.0 0.8862000865942656 3 P43487,P49792 2 +Vesicle-associated membrane-protein-associated protein [IPR016763] 0.5119509043927669 0.1690770859862758 0.8657360081664673 1.0 0.8910782589436175 2 Q9P0L0 1 +Ribosomal protein L14P [IPR000218] 0.5096899224806202 0.1655636916834656 0.8685003227090282 1.0 0.8928217282948538 2 Q6P1L8 1 +Heat shock protein Hsp90 family [IPR001404] 0.4065934065934085 0.1600420203286062 0.8728479733724555 1.0 0.8964688592498029 4 Q12931,P08238,P07900 3 +Coatomer gamma subunit [IPR017106] 0.5019379844961244 0.1540026128515243 0.8776076754066191 1.0 0.9005836703421571 2 Q9Y678 1 +Protein disulphide isomerase [IPR005792] 0.4969305331179163 0.1392567404332283 0.8892472728603085 1.0 0.9117453813932236 3 P07237,P13667 2 +CTP synthase [IPR004468] 0.4899870801033611 0.1376330486009716 0.8905304350736316 1.0 0.91266964006046 2 P17812 1 +Nucleolar, Nop52 [IPR010301] 0.4857881136951019 0.1322934336965344 0.8947522008792737 1.0 0.9166034757079448 2 Q14684 1 +Ezrin/radixin/moesin [IPR011174] 0.4894991922455421 0.1285585015360722 0.8977070047147289 1.0 0.9192365945494292 3 P35241,P15311 2 +Spectrin, beta subunit [IPR016343] 0.4783591731266261 0.1233603086082351 0.9018217860932856 1.0 0.9218708381996776 2 Q01082 1 +Mitofusin family [IPR027094] 0.4693152454780356 0.1133518907971656 0.909751579387287 1.0 0.9287856645239126 2 Q8IWA4 1 +ADP-ribosylation factor-like protein 8A/8B [IPR044154] 0.4654392764858004 0.1093466266631044 0.9129275655544008 1.0 0.9305657672661912 2 Q9NVJ2 1 +GDP-fucose protein O-fucosyltransferase [IPR019378] 0.4625322997416033 0.1064520817553485 0.915223672522522 1.0 0.9319845830499788 2 Q9Y2G5 1 +Bcl-2 family [IPR026298] 0.3752264640562316 0.1015498688348071 0.9191139725208132 1.0 0.9347518112706356 4 Q9BXK5,Q07812 2 +Bcl2-like [IPR002475] 0.3752264640562316 0.1015498688348071 0.9191139725208132 1.0 0.9347518112706356 4 Q9BXK5,Q07812 2 +Peptidase M3A/M3B [IPR045090] 0.463974151857831 0.0963864984280703 0.9232136148887182 1.0 0.9381231420309925 3 Q9BYT8,P52888 2 +Ribosomal protein L24e-related [IPR000988] 0.4463824289405695 0.0920173335635597 0.9266842678267944 1.0 0.9412498234383456 2 Q9UHA3 1 +SURP and G-patch domain-containing protein 1/2 [IPR040169] 0.4392764857881137 0.0865089348290032 0.9310618537341502 1.0 0.9452946464026976 2 Q8IWZ8 1 +Clathrin adaptor, mu subunit [IPR001392] 0.4481421647818978 0.0798732856599932 0.936338036884262 1.0 0.9487185152336552 3 Q9BXS5,Q9Y2T2 2 +Bax inhibitor 1-related [IPR006214] 0.4295865633074934 0.0797726113204419 0.9364181078843272 1.0 0.9487185152336552 2 Q9H3K2 1 +ADP/ATP carrier protein, eukaryotic type [IPR002113] 0.4423263327948284 0.0744381637946324 0.9406617427056204 1.0 0.9522109342968408 3 P05141,P12236 2 +HnRNP-L/PTB [IPR006536] 0.3410562735573433 0.0537576339892072 0.9571282638602808 1.0 0.965163303849358 4 Q8WVV9 1 +NADH:cytochrome b5 reductase-like [IPR001834] 0.3217054263565829 0.0470978044769867 0.962435277171211 1.0 0.9688758828318488 2 Q9UHQ9 1 +DNA2/NAM7-like helicase [IPR045055] 0.3345184227537189 0.0464360054669443 0.96296273924096 1.0 0.9688758828318488 4 P42694,Q9HCE1,Q92900 3 +Calcium uptake protein 1/2/3 [IPR039800] 0.3020025839793243 0.045861338472618 0.9634207691641204 1.0 0.9688758828318488 2 Q8IYU8 1 +Paraneoplastic encephalomyelitis antigen [IPR002343] 0.2958656330749299 0.0455979495541282 0.9636307034928951 1.0 0.9688758828318488 2 Q15717 1 +Alanine-tRNA ligase, class IIc [IPR002318] 0.2803617571059345 0.0451179817985552 0.964013268614374 1.0 0.9688758828318488 2 Q5JTZ9 1 +Alanine-tRNA ligase, eukaryota/bacteria [IPR023033] 0.2803617571059345 0.0451179817985552 0.964013268614374 1.0 0.9688758828318488 2 Q5JTZ9 1 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..284b02e02ed6f06049d85c9329c271878abbb675 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1-Cys peroxiredoxin [IPR045020]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-oxoisovalerate dehydrogenase subunit alpha [IPR034616]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S26 [IPR026140]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-keto-steroid reductase [IPR042829]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "4-aminobutyrate aminotransferase, eukaryotic [IPR004631]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "50S ribosomal protein uL4 [IPR013005]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABI family [IPR028457]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 10 [IPR042951]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1 complex subunit sigma [IPR044733]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit ATP5MJ, mitochondrial [IPR012574]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP synthase-coupling factor 6, mitochondrial [IPR008387]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase ARIP4-like [IPR044574]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "ATR-interacting protein [IPR033349]", "Abl interactor 1 [IPR028456]", "Acetate-CoA ligase [IPR011904]", "Acetyl-coenzyme A transporter 1-like [IPR024371]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Actin family [IPR004000]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Activating signal cointegrator 1-like [IPR039128]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active regulator of SIRT1 [IPR023262]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA thioesterase, long chain [IPR016662]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A diphosphatase NUDT19 [IPR039121]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine kinase [IPR001805]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase ALAT1/2-like [IPR045088]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid beta precursor protein binding family B member 1/2/3 [IPR039576]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Anion exchange protein 2 [IPR002978]", "Anion exchange protein [IPR001717]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-10 [IPR031291]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Antigen peptide transporter 2 [IPR005293]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAK [IPR026308]", "Apoptosis regulator BAX [IPR026304]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Apyrase [IPR009283]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arylacetamide deacetylase [IPR017157]", "Arylesterase [IPR002640]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Asparaginyl endopeptidase [IPR043577]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase B [IPR028772]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BTB-kelch protein [IPR017096]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bicaudal-D protein [IPR018477]", "Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [IPR013109]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bud22/Serum response factor-binding protein 1 [IPR037393]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-alcohol phosphatidyltransferase class-II family [IPR016270]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CGG triplet repeat-binding protein 1 [IPR033375]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COG complex component, COG2 [IPR009316]", "COMM domain-containing protein 1 [IPR037351]", "COMM domain-containing protein 10 [IPR037361]", "COMM domain-containing protein 5 [IPR037357]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF complex subunit CPSF4-like [IPR045348]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase activity and apoptosis inhibitor 1 [IPR038991]", "Cat eye syndrome critical region protein 2 [IPR029614]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cationic amino acid transport permease [IPR004755]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein C/Mif2/cnp3 [IPR028386]", "Centromere protein I [IPR012485]", "Centromere protein P [IPR027801]", "Centromere protein Q [IPR025212]", "Centromere protein U [IPR025214]", "Centromere subunit L [IPR025204]", "Centrosomal protein of 44kDa [IPR033603]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Choline transporter-like [IPR007603]", "Choline/ethanolamine phosphotransferase [IPR014472]", "Chondroitin N-acetylgalactosaminyltransferase [IPR008428]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin complexes subunit BAP18 [IPR037931]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homolog 2 [IPR042796]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Claspin [IPR024146]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 137 [IPR026680]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 167 [IPR028194]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 90-like [IPR024461]", "Coiled-coil domain-containing protein 93 [IPR039116]", "Coilin [IPR024822]", "Complex I intermediate-associated protein 30, mitochondrial [IPR039131]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit G2 [IPR024741]", "Conserved oligomeric Golgi complex subunit 5 [IPR019465]", "Conserved oligomeric Golgi complex subunit 6 [IPR010490]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1C [IPR027333]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-7 [IPR031223]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 1 [IPR014807]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP1/Nbp35 [IPR028601]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "D-glucuronyl C5-epimerase [IPR039721]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 16 [IPR028216]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA recombination and repair protein, RecA-like [IPR016467]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IA [IPR000380]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "DUF5568 family [IPR040419]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Dehydrogenase/reductase SDR member 4-like [IPR029511]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxynucleoside kinase [IPR002624]", "Deoxyribonuclease II [IPR004947]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dipeptidyl-peptidase 3 [IPR005317]", "Divergent protein kinase domain 2A/B [IPR020519]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 25-like [IPR044632]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [IPR039485]", "Dolichol kinase [IPR026566]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 SUMO-protein ligase PIAS1 [IPR027227]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RING2 [IPR037937]", "E3 ubiquitin-protein ligase RNF123/RSPRY1-like [IPR045129]", "E3 ubiquitin-protein ligase UBR7 [IPR040204]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Endonuclease III-like protein 1 [IPR030841]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Ephrin receptor type-A /type-B [IPR016257]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec10-like [IPR009976]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "F-box-like/WD repeat-containing protein Ebi-like [IPR045183]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FLYWCH-type zinc finger-containing protein 1/2 [IPR040312]", "FUN14 [IPR007014]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 2 [IPR030305]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferritin [IPR001519]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fyv10 family [IPR045098]", "Fyv7/TAP26 [IPR013730]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase 2-like [IPR045130]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GOSR2/Membrin/Bos1 [IPR027027]", "GPI ethanolamine phosphate transferase 2 [IPR039527]", "GPI mannosyltransferase [IPR005599]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI transamidase subunit PIG-U [IPR009600]", "GPI-anchor transamidase [IPR028361]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "Galactokinase [IPR000705]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucose-methanol-choline oxidoreductase [IPR012132]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 13 [IPR004139]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 43 [IPR005027]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Groucho/transducin-like enhancer [IPR009146]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "H/ACA ribonucleoprotein complex, subunit Nop10 [IPR007264]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HEXIM [IPR024872]", "HMG domain-containing protein 4 [IPR042477]", "HMG-CoA lyase [IPR043594]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 12A [IPR026685]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase XPB/Ssl2 [IPR001161]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histidine-tRNA ligase [IPR015807]", "Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit [IPR004516]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone acetyltransferases subunit 3 [IPR019340]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1 [IPR038035]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase SETD2, animal [IPR042294]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "ING family [IPR028651]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of growth protein 4/5 [IPR028638]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B alpha/beta/delta [IPR011559]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol monophosphatase-like [IPR000760]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integral membrane protein SYS1 [IPR016973]", "Integral membrane protein SYS1-related [IPR019185]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 10 [IPR026164]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 5 [IPR040316]", "Integrator complex subunit 8 [IPR038751]", "Integrin alpha chain [IPR000413]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intracellular chloride channel [IPR002946]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intraflagellar transport protein 81 [IPR029600]", "Intron Large complex component GCFC2-like [IPR012890]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KRR1 interacting protein 1 [IPR018034]", "Kelch-like ECH-associated protein 1 [IPR030563]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore Mis14/Nsl1 [IPR013950]", "Kinetochore protein Spc25 [IPR045143]", "Kintoun [IPR034727]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LIM domain only protein 7 [IPR029978]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "Las1 [IPR007174]", "Learning associated protein 18-like [IPR018784]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lipid droplet-associated hydrolase [IPR019363]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Luc7-related [IPR004882]", "Lunapark family [IPR040115]", "Lupus La protein [IPR002344]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase phosphoprotein 6 [IPR019324]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "METTL16/RlmF family [IPR010286]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MKRN-like [IPR045072]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "Macrophage migration inhibitory factor [IPR001398]", "Magnesium transporter protein 1 [IPR006844]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannose-P-dolichol utilization defect 1 protein [IPR016817]", "Mannosyltransferase ALG2 [IPR027054]", "Med25/PTOV1 [IPR045105]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med20 [IPR013921]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med27 [IPR021627]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribose-1-phosphate isomerase [IPR005251]", "Methylthiotransferase [IPR005839]", "Methyltransferase METTL16/PsiM [IPR017182]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microsomal glutathione S-transferase 1-like [IPR040162]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondria fission 1 protein [IPR016543]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial calcium uniporter regulator 1 [IPR012439]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein Mtm1-like [IPR045315]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit TIM22 [IPR039175]", "Mitochondrial import inner membrane translocase subunit Tim10 [IPR027100]", "Mitochondrial import inner membrane translocase subunit Tim29 [IPR019322]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdenum cofactor biosynthesis C [IPR023045]", "Molybdenum cofactor biosynthesis protein A [IPR013483]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 12 [IPR030576]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetylglucosaminyl phosphatidylinositol deacetylase-related [IPR003737]", "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase [IPR039516]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase 1, beta subcomplex, subunit 6 [IPR019174]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, iron-sulphur subunit 5 [IPR019342]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Nck-associated protein 1 [IPR019137]", "Nectin-2 [IPR033318]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neural cell adhesion [IPR009138]", "Neural cell adhesion molecule 1 [IPR033019]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Non-specific endonuclease [IPR040255]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nuclear MIS12/MIND complex subunit PMF1/Nnf1 [IPR007128]", "Nuclear RNA export factor [IPR030217]", "Nuclear RNA-splicing-associated protein, SR-25 [IPR019532]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 2 [IPR027157]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear hormone receptor [IPR001723]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear speckle splicing regulatory protein 1 [IPR042816]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar and spindle-associated protein 1 [IPR026756]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar protein of 40kDa [IPR037320]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase 6 [IPR037994]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "Nucleotide-sugar transporter [IPR007271]", "NudC family [IPR037898]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ODR-4-like [IPR029454]", "Occludin [IPR002958]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Oligosaccharyltransferase complex subunit OSTC [IPR042416]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 2 [IPR007220]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 6 [IPR008721]", "Origin recognition complex, subunit 6, metazoa/plant [IPR020529]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IB [IPR027256]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PDZ domain-containing protein 8 [IPR039275]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PSME3-interacting protein [IPR039845]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic antigen Ma [IPR026523]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Patatin-like phospholipase domain-containing protein 4 [IPR033902]", "Patatin-like phospholipase domain-containing protein [IPR033562]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1A, chymotrypsin family [IPR001314]", "Peptidase S1C [IPR001940]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal biogenesis factor 11 [IPR008733]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phenylalanyl-tRNA synthetase, class IIc, mitochondrial [IPR004530]", "Phorbol-12-myristate-13-acetate-induced protein 1 [IPR024140]", "Phosducin-like [IPR045037]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [IPR042165]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like [IPR044596]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phospholipase B-like [IPR007000]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Platelet-activating factor acetylhydrolase, eucaryote [IPR016715]", "Platelet-activating factor acetylhydrolase-like [IPR005065]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polycomb protein EED [IPR037352]", "Polyprenol kinase family [IPR032974]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA splicing factor [IPR022209]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable E3 ubiquitin-protein ligase makorin-2 [IPR026293]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein CIP2A [IPR042510]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM3C [IPR039219]", "Protein FAM8A1 [IPR039871]", "Protein FMC1 homologue [IPR037667]", "Protein Fyv10/E3 ubiquitin-protein transferase MAEA [IPR027714]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LCHN/Anr2 [IPR018626]", "Protein LIN-9/Protein ALWAYS EARLY [IPR010561]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein Mon2-like [IPR026829]", "Protein NCBP2AS2 [IPR042407]", "Protein NDRG3 [IPR030692]", "Protein Njmu-R1 [IPR028280]", "Protein OS-9-like [IPR045149]", "Protein PCF11-like [IPR045154]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein TFG [IPR033512]", "Protein XRP2 [IPR039093]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C, alpha/beta/gamma types [IPR014375]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF1387 [IPR009816]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF4660 [IPR029089]", "Protein of unknown function DUF719 [IPR007998]", "Protein of unknown function DUF842, eukaryotic [IPR008560]", "Protein of unknown function DUF92, TMEM19 [IPR002794]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein suppressor of sable-like [IPR045124]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein unc-119 homologue A-like [IPR032977]", "Protein virilizer [IPR026736]", "Protein-L-histidine N-pros-methyltransferase [IPR007884]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA methyltransferase [IPR003750]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAB11-binding protein RELCH [IPR040362]", "RAD51-associated protein 1 [IPR026632]", "RFT1 [IPR007594]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II elongation factor ELL [IPR031184]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein Nova-1 [IPR033086]", "RNA-binding region-containing protein RBM41/RNPC3 [IPR045164]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit Pop5/Rpp14/Rnp2-like [IPR002759]", "RNase P subunit p30 [IPR002738]", "RPA-related protein RADX [IPR040893]", "RSBN1/Dpy-21 [IPR026306]", "RZZ complex, subunit Zw10 [IPR009361]", "RZZ complex, subunit Zwilch [IPR018630]", "Rab GDI protein [IPR000806]", "Rab11-family interacting protein class I [IPR037789]", "Rab12 [IPR041830]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab35 [IPR041815]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Rab29/Rab38/Rab32 [IPR030697]", "Ras-related protein Ral [IPR028412]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulophagy receptor 1/3 [IPR043384]", "Reticulophagy regulator 3 [IPR033361]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease P protein subunit Rpp38 [IPR042848]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein 7 [IPR040446]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24e [IPR023438]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27/L41, mitochondrial [IPR019189]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome biogenesis protein Slx9-like [IPR028160]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "Ribosome-releasing factor 2, mitochondrial [IPR030851]", "RidA family [IPR006056]", "Romo1/Mgr2 [IPR018450]", "Root UVB sensitive family [IPR006968]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAGA-associated factor 29 [IPR037802]", "SAP30-binding protein [IPR012479]", "SCAMP [IPR007273]", "SERRATE/Ars2 [IPR039727]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNARE associated Golgi protein [IPR032816]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "STEEP-like [IPR029704]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BAF60B [IPR030090]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sds3-like [IPR013907]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/Arginine-related protein 53 [IPR034604]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shikimate kinase/Threonine synthase-like 1 [IPR000623]", "Shikimate kinase/gluconokinase [IPR031322]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smooth muscle protein/calponin [IPR003096]", "Snapin [IPR017246]", "Snapin/Pallidin/Snn1 [IPR028119]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium/solute symporter [IPR001734]", "Sodium:dicarboxylate symporter [IPR001991]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 12 member 9 [IPR030345]", "Solute carrier family 25 member 44 [IPR042164]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sororin protein [IPR018605]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle and kinetochore-associated protein 3 [IPR033341]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 3B subunit 5/RDS3 complex subunit 10 [IPR009846]", "Splicing factor 3B, subunit 5 [IPR017089]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Stromal interaction molecule 1 [IPR030463]", "Stromal interaction molecule [IPR037608]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, cytochrome b556 subunit [IPR014314]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit [IPR000701]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar phosphate transporter [IPR000849]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of hairless-like [IPR040159]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntaxin-3 [IPR031186]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA element modulatory factor 1 DNA binding [IPR022092]", "TB2/DP1/HVA22-related protein [IPR004345]", "TE2IP/Rap1 [IPR039595]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TREX component Tex1/THOC3 [IPR040132]", "Taxilin family [IPR026183]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Telomeric repeat-binding factor 1/2 [IPR017357]", "Telomeric repeat-binding factor 2 [IPR030657]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 15 [IPR042418]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine synthase-like [IPR004450]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A [IPR030549]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription initiation factor TAFII31 [IPR003162]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulator TACO1-like [IPR002876]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 223 [IPR026100]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 41A/B [IPR045014]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transmembrane protein TqsA-like [IPR002549]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm3 [IPR040002]", "UAA transporter [IPR013657]", "UAP56-interacting factor [IPR009782]", "UBAP2/protein lingerer [IPR022166]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "UPF0767 family [IPR031933]", "USP39 [IPR033809]", "UV excision repair protein Rad23 [IPR004806]", "UbiA prenyltransferase domain containing protein 1 [IPR026046]", "UbiA prenyltransferase family [IPR000537]", "Ubinuclein-1 [IPR026936]", "Ubiquinol-cytochrome c chaperone, CBP3 [IPR007129]", "Ubiquinol-cytochrome c chaperone/UPF0174 [IPR021150]", "Ubiquinone biosynthesis protein COQ9 [IPR012762]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin domain-containing protein UBFD1 [IPR039120]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-associated protein 1 [IPR038870]", "Ubiquitin-fold modifier-conjugating enzyme 1 [IPR014806]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised conserved protein UCP013899, metal binding [IPR016617]", "Uncharacterised protein family UPF0390 [IPR019034]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family UPF0640 [IPR028183]", "Uncharacterised protein family, TMEM59 [IPR022065]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Ureohydrolase [IPR006035]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar ATPase assembly integral membrane protein Vma21 [IPR019013]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vang-like protein [IPR009539]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "WASH complex subunit 7 [IPR027307]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "Xyloside xylosyltransferase 1 [IPR042465]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YIP1 family member 3 [IPR026637]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter Msc2-like [IPR045316]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA export factor Gle2/RAE1 [IPR037631]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein RRP36 [IPR009292]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7 [IPR028590]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-specific 2-thiouridylase [IPR004506]"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACSS1", "ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFG3L2", "AGA", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANKLE2", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEX1", "API5", "APLP2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFIP1", "ARG2", "ARHGDIA", "ARID1A", "ARID3B", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC6", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATXN2L", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAX", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCL2L13", "BCLAF1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPTF", "BRCA1", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUD23", "BUD31", "BYSL", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf35", "C1orf52", "C2CD5", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf33", "CAAP1", "CAB39", "CAD", "CALR", "CALU", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CAST", "CBR1", "CBR4", "CBX2", "CBX3", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC59", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC37", "CDC40", "CDC42", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK5RAP3", "CDKAL1", "CEBPZ", "CECR2", "CELF2", "CENPC", "CENPI", "CENPL", "CENPP", "CENPQ", "CENPU", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHDH", "CHERP", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHST14", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COIL", "COLGALT1", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF2", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSGALNACT2", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CWF19L1", "CXorf56", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DCAF1", "DCAF16", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DECR1", "DECR2", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAJA1", "DNAJA2", "DNAJC10", "DNAJC13", "DNAJC25", "DNAJC8", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLK", "DOLPP1", "DPM1", "DPP3", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EED", "EEF1A2", "EEF1E1", "EEF1G", "EFHD1", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2B1", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENDOD1", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESF1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAM114A2", "FAM120A", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM207A", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIS1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMC1", "FMR1", "FN3KRP", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GCAT", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDI2", "GEMIN4", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GHITM", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLS", "GLUD1", "GM2A", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRPEL1", "GRSF1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDHD5", "HEATR1", "HEBP1", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTRA2", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS10", "INTS13", "INTS14", "INTS3", "INTS5", "INTS8", "IPO4", "IPO5", "IRS4", "ISCU", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KDELR1", "KDELR3", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF5B", "KLC1", "KMT2A", "KMT2B", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LETMD1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMF2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT3", "LRPAP1", "LRPPRC", "LRRC47", "LSM12", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LZIC", "M6PR", "MACF1", "MAEA", "MAGED2", "MAGT1", "MAK16", "MAN1A2", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL9", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPST", "MPV17L2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTR", "MTX1", "MTX2", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYO18A", "NAA15", "NAA40", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NAT10", "NAXE", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF1", "NDUFB10", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NFS1", "NHP2", "NIP7", "NIPBL", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NSA2", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT19", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUSAP1", "NXF1", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH2", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PAWR", "PAXBP1", "PBRM1", "PC", "PCBD1", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PELO", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGS1", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIP4K2C", "PISD", "PITPNB", "PKM", "PKMYT1", "PLA2G15", "PLBD2", "PLEC", "PLIN3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA4", "PNPT1", "POFUT1", "POFUT2", "POLA1", "POLA2", "POLD1", "POLD2", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIE", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2B", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM23", "RBM26", "RBM27", "RBM39", "RBM45", "RBM5", "RBM6", "RBM8A", "RBPJ", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFT1", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPEP", "ROMO1", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RSRC1", "RTCB", "RTFDC1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARS", "SARS2", "SART1", "SBDS", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B5", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35A4", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLK", "SLTM", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMIM12", "SMIM4", "SMPD4", "SMU1", "SMYD3", "SNAPIN", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPNS1", "SPOUT1", "SPR", "SPTBN1", "SPTBN2", "SQLE", "SRFBP1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF6", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SURF6", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYS1", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARS", "TARS2", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TECR", "TEFM", "TERF2", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM29", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TLE3", "TM7SF2", "TM9SF3", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM19", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM223", "TMEM230", "TMEM245", "TMEM33", "TMEM41A", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMX2", "TNPO1", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPX2", "TRABD", "TRAM1", "TRAP1", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TST", "TTC19", "TTC26", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UAP1", "UBA1", "UBA2", "UBA6", "UBAP1", "UBAP2L", "UBE3A", "UBE3C", "UBFD1", "UBIAD1", "UBN1", "UBR4", "UBR7", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC119", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRQ", "URB1", "UROD", "USMG5", "USP10", "USP14", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP3", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "WAPL", "WARS", "WARS2", "WASHC4", "WBP11", "WBP2", "WDR12", "WDR18", "WDR33", "WDR41", "WDR46", "WDR74", "WDR82", "WDR91", "WFS1", "WIPI2", "WTAP", "XAB2", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YEATS2", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YLPM1", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H14", "ZC3H8", "ZCCHC17", "ZCCHC3", "ZMPSTE24", "ZMYND8", "ZNF326", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZWILCH"], "leading_proteins": ["AARS2", "ABCB1", "ABCB7", "ACP6", "AP1M1", "AP3M1", "ARL2", "ARL6IP5", "ARL8B", "ATAD3B", "ATP13A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP6V0A2", "ATP7A", "ATP7B", "BAG3", "BAG5", "BAX", "BCL2L13", "BCLAF1", "CHST14", "CLPTM1", "CNNM4", "COPG1", "CPSF7", "CPT2", "CPVL", "CTPS1", "CYB5R1", "CYP51A1", "DNM2", "EIF2B4", "ELAVL1", "EMC3", "ERAP1", "ERGIC2", "ERGIC3", "EXOSC3", "EZR", "FLOT1", "GHITM", "GNA13", "GNAI2", "GPR107", "HACD2", "HELZ", "HMOX2", "HNRNPLL", "HSP90AA1", "HSP90AB1", "IPO5", "KDELR1", "KHDRBS3", "LNPEP", "MFN1", "MFSD8", "MICU2", "MINPP1", "MOV10", "MPV17L2", "MRI1", "MRPL14", "MTMR12", "MTX1", "NAP1L1", "NEDD4L", "NLN", "NPEPPS", "NT5C2", "NT5DC1", "NUCB2", "P4HB", "PABPC1", "PCYOX1", "PDIA4", "PFDN1", "PHB", "PIGK", "POFUT2", "PPT2", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSME2", "PTGES2", "QKI", "RABAC1", "RANBP1", "RANBP2", "RARS", "RDX", "REEP2", "REEP5", "RHOT1", "RNF20", "RPRD1A", "RPRD2", "RRP1B", "RSL24D1", "SCAMP1", "SCAMP2", "SCARB2", "SCO2", "SCPEP1", "SEC22B", "SF1", "SFXN4", "SLC12A9", "SLC16A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A16", "SLC25A17", "SLC25A21", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SMC1A", "SMC3", "SMC4", "SPNS1", "SPTBN1", "STOM", "STX10", "STX3", "STX6", "STX7", "STX8", "SUGP1", "SYNCRIP", "TAF15", "TAP1", "THOP1", "TIMM17A", "TMED2", "TMED7", "TMEM70", "TNPO1", "TPD52", "TPM4", "TRAP1", "TSPAN3", "TUBB", "TUBB2B", "UPF1", "VAPA", "VDAC1", "VPS33B", "VPS45", "YIF1B", "ZNF326"]} \ No newline at end of file diff --git a/interpro_homologous_superfamily/advanced/idx2term.json b/interpro_homologous_superfamily/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..551a911eb1304886fab42c0c0a0821f7d76e6844 --- /dev/null +++ b/interpro_homologous_superfamily/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier domain superfamily [IPR023395]", "1": "Glycoside hydrolase superfamily [IPR017853]", "2": "Alpha/Beta hydrolase fold [IPR029058]"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/advanced/plot_0.png b/interpro_homologous_superfamily/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..3c6cb176d7015c77f5334e91fe89a0b7d329cb1a --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid 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b/interpro_homologous_superfamily/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..481c95fd49ff39f4ff00e1c81f69de5878b8c931 --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c641b2d836552e3afd2dc85bc026d0f26f0d43b782f3f56fd6a9a201202983b6 +size 147731 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5384c4ffd50c210c47ec265752ebab1715c93d17 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier domain superfamily [IPR023395] 15 25 3.3156711128906715 0.0009142335245009 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.0004580163913592 0.1675604235637086 0.0523352985295366 2.9874917190946567e-05 1.1113235605961464e-09 +Glycoside hydrolase superfamily [IPR017853] 5 15 2.582552500054535 0.00980724394425 7.094660194174757 15.565533980582524 0.5992585613623983 0.1928722204186086 2.565315823223627 1.245604487832095 1.9386029676344616 0.2695693578719223 4.198132317436559e-06 1.0 0.0260710687649276 2.914413274201657e-05 0.0012730265791845 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 3 6 2.3897370946713883 0.0168604372934824 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 3.811917339060444e-05 0.0014481500629001 0.0001833288791406 0.000142755965642 0.0019884945269669 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 3 16 2.3024726059192533 0.0213085345552124 4.434466019417476 16.66747572815534 0.2357810231502951 0.5538564173973619 3.0446637157573253 1.3736813401106382 0.9202997959616273 0.3110539503026115 0.0069459336161985 0.0053672672920639 0.0013656945298514 0.0020705519968491 0.0233101974365333 +Alpha/Beta hydrolase fold [IPR029058] 9 26 2.199349390402459 0.0278530882961649 7.793689320388349 25.487864077669904 0.3803730368869525 0.1931612116461074 2.8504230618688027 2.5849355029363217 1.9090082785106757 0.2379814650369476 1.840761596590995e-05 7.179758233963367e-07 3.5484935840982423e-06 4.2773306632342085e-06 7.825314737739928e-05 +Histidine phosphatase superfamily [IPR029033] 3 6 1.9951922873068004 0.0460219119163423 1.1262135922330097 5.514563106796117 0.7684120115144248 0.3501978831807532 1.087703661549979 0.6771453167512235 0.986671075305162 0.2738673806375665 0.0028771223664049 0.0786913117950012 0.152955667850895 0.0074273483269255 0.0078812527225172 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..405da54dc8d1b5a8dd8ac45e6682a02eef7ac8cc --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 950, + "title": "Average number of proteins per term", + "value": 4.671578947368421 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5fcf5c91fb8b7d07a7c6dca9e04178ed0f835042 --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1c2217fd109e98d47e77d34442d6e7620934f37e --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,124 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial carrier domain superfamily [IPR023395] 0.7470280292359393 3.3156711128906715 0.0009142335245009 0.580595363842753 0.127827185208763 25 O43772,Q86VD7,Q9Y619,Q9H2D1,Q8TBP6,Q9BQT8,Q70HW3,Q9BSK2,Q9NZJ7,Q9UBX3,O75746,Q96H78,P16260,Q9Y6C9,Q9UJS0 15 +Glycoside hydrolase superfamily [IPR017853] 0.7114328192238958 2.582552500054535 0.00980724394425 0.9999141465798822 0.1296369853497505 15 P16278,P06280,Q9BTY2,P54802,O60502 5 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.8969836854872061 2.3897370946713883 0.0168604372934824 0.9999999035251012 0.1421108815695176 6 Q9UMX5,O43169,Q8WUJ1 3 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.641248180605569 2.3024726059192533 0.0213085345552124 0.9999999987012932 0.1467956846877812 16 Q9H7Z7,P78417,Q13505 3 +Alpha/Beta hydrolase fold [IPR029058] 0.5715088232472687 2.199349390402459 0.0278530882961649 0.9999999999977852 0.1787867154145723 26 P07099,Q9H3G5,Q9NUJ1,Q9H6V9,P50897,P42785,Q9UMR5,Q8NCC3,Q9HB40 9 +Histidine phosphatase superfamily [IPR029033] 0.8015192142793451 1.9951922873068004 0.0460219119163423 1.0 0.2428934240029177 6 Q9NPH0,P11117,Q9UNW1 3 +P-type ATPase, A domain superfamily [IPR008250] 0.7049311463738145 1.894560041419152 0.0581507128361031 1.0 0.2715096729694201 9 Q04656,P16615,P98194,Q9HD20,P35670,P20020,P23634 7 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.7049311463738145 1.894560041419152 0.0581507128361031 1.0 0.2715096729694201 9 Q04656,P16615,P98194,Q9HD20,P35670,P20020,P23634 7 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.7049311463738145 1.894560041419152 0.0581507128361031 1.0 0.2715096729694201 9 Q04656,P16615,P98194,Q9HD20,P35670,P20020,P23634 7 +SNARE [IPR010989] 0.754605487241923 1.878681550991727 0.0602879883830909 1.0 0.2729595242333845 7 O43752,O15400,Q13277,O60499,O14653 5 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.6960340857549782 1.8519977584906195 0.0640261447835532 1.0 0.2855626175792283 9 Q03518,O14678,P08183,P33527,O75027 5 +GroES-like superfamily [IPR011032] 0.7019710430706443 1.7903687674627848 0.0733946478229556 1.0 0.3039046763175749 8 Q8N4Q0 1 +Porin domain superfamily [IPR023614] 0.8580004960648473 1.7872516714487563 0.0738968212940629 1.0 0.3039046763175749 4 P21796 1 +LEM/LEM-like domain superfamily [IPR011015] 0.7460473978188771 1.7578670224234323 0.0787701381340229 1.0 0.3164592720067027 6 Q86XL3,P50402 2 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.7786366931692127 1.7353059191754268 0.0826866338861762 1.0 0.3164592720067027 5 P55786,Q9UIQ6,Q9NZ08 3 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.7786366931692127 1.7353059191754268 0.0826866338861762 1.0 0.3164592720067027 5 P55786,Q9UIQ6,Q9NZ08 3 +GOLD domain superfamily [IPR036598] 0.7784243706259903 1.7344208015858982 0.0828434468495489 1.0 0.3164592720067027 5 Q9H3P7,Q9Y3B3 2 +Haem oxygenase-like, multi-helical [IPR016084] 0.9757751937984468 1.732204000597203 0.0832372470036126 1.0 0.3164592720067027 2 P30519 1 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.8438914027149326 1.7319708324366976 0.0832787557912375 1.0 0.3164592720067027 4 P07437,Q9BVA1,Q9BUK6 3 +Sterile alpha motif/pointed domain superfamily [IPR013761] 0.6680060203611466 1.716679871362839 0.0860376798944406 1.0 0.3218247398144295 9 Q15375,Q13586 2 +Glycosyl hydrolase, all-beta [IPR013780] 0.6815631199745406 1.6950059002547364 0.0900743015008864 1.0 0.3245005766991641 8 P06280 1 +GMP phosphodiesterase, delta subunit superfamily [IPR037036] 0.933139534883718 1.562570910628414 0.1181535548519736 1.0 0.3644346659395291 2 A6NIH7 1 +Tetraspanin, EC2 domain superfamily [IPR008952] 0.9192506459948232 1.5072088176986629 0.1317571407881947 1.0 0.388724483691879 2 O60637 1 +Cytochrome P450 superfamily [IPR036396] 0.9111757105943072 1.4750181552949146 0.1402076624473887 1.0 0.4018645874802021 2 Q16850 1 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.4971784006077485 1.461255514502199 0.1439453331668387 1.0 0.4045800784275054 20 Q8NBM8,Q96CU9,O95831,P50336,P00390,Q9UHG3,Q6NUM9,Q14534 8 +HAD-like superfamily [IPR036412] 0.4992764999392008 1.454391672360369 0.1458377474367354 1.0 0.4051048539909316 19 Q04656,P16615,P05023,P98194,Q9HD20,P35670,P20020,Q969T7,Q5TFE4,P49902,P23634 11 +HAD superfamily [IPR023214] 0.4992764999392008 1.454391672360369 0.1458377474367354 1.0 0.4051048539909316 19 Q04656,P16615,P05023,P98194,Q9HD20,P35670,P20020,Q969T7,Q5TFE4,P49902,P23634 11 +GINS, helical bundle-like domain superfamily [IPR036224] 0.8924418604651168 1.4003678148940517 0.161403202840157 1.0 0.4343712257737938 2 Q9BRX5 1 +MFS transporter superfamily [IPR036259] 0.55427637511435 1.3910870532880235 0.1641990303415061 1.0 0.4381715697315474 12 Q14728,Q9H2V7,Q8NHS3,Q16625,P53985,P41440 6 +Choline/Carnitine o-acyltransferase, domain 2 [IPR042231] 0.8879198966408282 1.3823627897839132 0.1668603353918549 1.0 0.4427858062074364 2 P23786 1 +G protein alpha subunit, helical insertion [IPR011025] 0.7412960776561075 1.3244413933459098 0.185356494980474 1.0 0.4670787008791786 4 Q14344,P04899 2 +C-type lectin-like/link domain superfamily [IPR016186] 0.863372093023243 1.2848007967693271 0.198861903877912 1.0 0.4794893621421736 2 Q5KU26 1 +Cyclic nucleotide-binding-like [IPR018490] 0.671202445570381 1.2806828501098733 0.2003050859762252 1.0 0.4805298779732675 5 Q9Y4G8,Q8IY17 2 +Band 7/SPFH domain superfamily [IPR036013] 0.5779136080481719 1.1990186270273984 0.2305207027853959 1.0 0.5315404554517624 8 O75955,Q9UJZ1,Q14254,Q99623,P35232,P27105 6 +Ricin B-like lectins [IPR035992] 0.8476409892160304 1.155413486906653 0.2479211415508895 1.0 0.5549858281071317 3 Q9UBG0 1 +FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156] 0.6956004974637662 1.1415764923206957 0.2536300999742176 1.0 0.5556023894530164 4 O95831 1 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.8436187399030685 1.1408653522521912 0.2539259597079577 1.0 0.5556023894530164 3 P07437,Q9BVA1 2 +Tubulin/FtsZ, C-terminal [IPR008280] 0.8436187399030685 1.1408653522521912 0.2539259597079577 1.0 0.5556023894530164 3 P07437,Q9BVA1 2 +Tubulin, C-terminal [IPR023123] 0.8436187399030685 1.1408653522521912 0.2539259597079577 1.0 0.5556023894530164 3 P07437,Q9BVA1 2 +Beta-hexosaminidase-like, domain 2 [IPR029018] 0.8384367544717396 1.1221452168392894 0.2618007010620098 1.0 0.5601591576777236 3 P54802 1 +Isoprenoid synthase domain superfamily [IPR008949] 0.8145994832041191 1.092687722358978 0.2745309322277842 1.0 0.5708278604564575 2 P37268 1 +C-type lectin fold [IPR016187] 0.8184168012924223 1.0501056131366855 0.2936695582962345 1.0 0.5877223936285962 3 Q9UBG0,Q5KU26 2 +FAD-binding, type PCMH-like superfamily [IPR036318] 0.800387596899208 1.0374152180986391 0.2995423890354445 1.0 0.5916117870762418 2 Q15392 1 +FAD-binding, type PCMH, subdomain 2 [IPR016169] 0.800387596899208 1.0374152180986391 0.2995423890354445 1.0 0.5916117870762418 2 Q15392 1 +Class II aldolase/adducin N-terminal domain superfamily [IPR036409] 0.7990956072351465 1.0324115365961235 0.3018793697753894 1.0 0.5937585947963145 2 Q9UEY8 1 +BAG domain superfamily [IPR036533] 0.8080775444264999 1.0131123824863668 0.3110064844266489 1.0 0.6003503217759993 3 O95817,Q9UL15 2 +Fibronectin type II domain superfamily [IPR036943] 0.7993035655834033 0.9818548582890252 0.3261713575818274 1.0 0.609966121462079 3 Q9UBV2 1 +Kringle-like fold [IPR013806] 0.7993035655834033 0.9818548582890252 0.3261713575818274 1.0 0.609966121462079 3 Q9UBV2 1 +DHS-like NAD/FAD-binding domain superfamily [IPR029035] 0.5823367333056533 0.902027221087641 0.3670424077333842 1.0 0.6534309250887126 5 P49366,Q13423 2 +Heavy metal-associated domain superfamily [IPR036163] 0.7731825525040401 0.8896883807239749 0.3736332347440552 1.0 0.6538758543572126 3 Q9NVT9,P35670 2 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.5248213436628226 0.8331140100141847 0.4047804329240341 1.0 0.6676066168017923 7 Q10713,P22695 2 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.7418001997693924 0.7812265093277032 0.4346692848435463 1.0 0.6928453365794781 3 P10321 1 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.7418001997693924 0.7812265093277032 0.4346692848435463 1.0 0.6928453365794781 3 P10321 1 +Ubiquitin-like domain superfamily [IPR029071] 0.3610722462857668 0.7778910563976205 0.4366332412213778 1.0 0.6940744575438728 33 Q9Y4G8,P46379,Q9NRR5,Q92575,Q96K76,Q9Y4F1 6 +Thioredoxin-like superfamily [IPR036249] 0.3764985036645466 0.7749262042997747 0.4383832669147622 1.0 0.6941068392817069 49 Q9H7Z7,Q9H1E5,Q92575,O43819,Q8IXB1,P78417 6 +Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695] 0.7238372093023263 0.7496916944664244 0.4534404108937038 1.0 0.7070188654780204 2 P54136 1 +AH/BAR domain superfamily [IPR027267] 0.4721882776760764 0.6891772605267156 0.4907117248486079 1.0 0.7381891676186472 8 Q9UQB8,Q9Y5X1 2 +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.3898651711705507 0.6884959551000992 0.491140516613215 1.0 0.7381891676186472 18 P28074,P28072,Q06203,P49721,P28070,P20618 6 +Galactose-binding-like domain superfamily [IPR008979] 0.4884660357202607 0.6692869629033255 0.5033124415524948 1.0 0.7421662985130154 7 Q15375,P16278 2 +HIT-like superfamily [IPR036265] 0.5716722591412614 0.6595913983664997 0.5095160756433983 1.0 0.7446773413249668 4 Q9NQE9 1 +Dbl homology (DH) domain superfamily [IPR035899] 0.6821705426356465 0.6041223163974845 0.5457623235681066 1.0 0.7667428176185325 2 Q9Y4F1 1 +SKP1/BTB/POZ domain superfamily [IPR011333] 0.4703341491887045 0.5895650056645175 0.5554823186099931 1.0 0.7737656930784361 7 Q14145,O43791 2 +Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155] 0.6715116279069777 0.5686498171910445 0.5695938099264728 1.0 0.7853615666620453 2 Q9H267 1 +MAN1, winged-helix domain [IPR041885] 0.6563307493540071 0.519585830964695 0.6033522757886349 1.0 0.8044345662380643 2 Q9Y2U8 1 +RmlC-like jelly roll fold [IPR014710] 0.425409276048993 0.5137329495835661 0.6074387118927711 1.0 0.8044345662380643 9 Q9Y4G8,Q9BV57,P38435,Q8IY17 4 +Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080] 0.6543927648578832 0.5134533576728604 0.6076342295628749 1.0 0.8044345662380643 2 Q9BYT8 1 +SH3-like domain superfamily [IPR036028] 0.3552472686875742 0.5110105902324678 0.6093436412348927 1.0 0.8044345662380643 24 Q96PC5,Q5JRA6,Q9UQB8,Q9Y5X1 4 +Zinc finger, NHR/GATA-type [IPR013088] 0.6518087855297038 0.5053248206020252 0.6133307124775158 1.0 0.8044345662380643 2 Q8WXI9 1 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.4498115859778113 0.5016339029023796 0.6159250666607621 1.0 0.8044345662380643 7 P98175,Q92804 2 +Sec1-like superfamily [IPR036045] 0.4824697490180321 0.4996838826814576 0.617297682934262 1.0 0.8044345662380643 5 Q9NRW7 1 +Sec1-like, domain 1 [IPR043154] 0.4824697490180321 0.4996838826814576 0.617297682934262 1.0 0.8044345662380643 5 Q9NRW7 1 +Sec1-like, domain 3a [IPR043127] 0.4824697490180321 0.4996838826814576 0.617297682934262 1.0 0.8044345662380643 5 Q9NRW7 1 +Sec1-like, domain 2 [IPR027482] 0.4824697490180321 0.4996838826814576 0.617297682934262 1.0 0.8044345662380643 5 Q9NRW7 1 +Proteasome activator PA28, C-terminal domain superfamily [IPR036997] 0.6445912186715317 0.4711836771875148 0.6375095740198997 1.0 0.8118382737222989 3 Q9UL46 1 +Proteasome activator PA28, N-terminal domain superfamily [IPR036996] 0.6445912186715317 0.4711836771875148 0.6375095740198997 1.0 0.8118382737222989 3 Q9UL46 1 +Proteasome activator superfamily [IPR036252] 0.6445912186715317 0.4711836771875148 0.6375095740198997 1.0 0.8118382737222989 3 Q9UL46 1 +Zinc finger, CCHC-type superfamily [IPR036875] 0.5183292554701568 0.4707997936620025 0.6377837119084688 1.0 0.8118382737222989 4 Q16629 1 +Immunoglobulin-like domain superfamily [IPR036179] 0.3907084028551533 0.4272425447619731 0.669202676234576 1.0 0.8297183170522425 11 P35613,Q08722,P10321 3 +EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044] 0.6273553682113399 0.4221105392248353 0.6729443355898543 1.0 0.8313356551500151 3 Q6NUQ1 1 +LSM domain superfamily [IPR010920] 0.3838847010020122 0.361651951067913 0.7176121373421038 1.0 0.8575239377044007 10 P62310,Q9Y4Y9 2 +PABC (PABP) domain [IPR036053] 0.6012924071082432 0.3523795556538286 0.7245536321997357 1.0 0.8582617837777418 3 Q13310,P11940 2 +Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291] 0.5907622739018058 0.3314009783594102 0.7403416259863029 1.0 0.861045334280524 2 O00754 1 +Glycoside hydrolase family 38, central domain superfamily [IPR037094] 0.5907622739018058 0.3314009783594102 0.7403416259863029 1.0 0.861045334280524 2 O00754 1 +Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330] 0.5907622739018058 0.3314009783594102 0.7403416259863029 1.0 0.861045334280524 2 O00754 1 +Glycoside hydrolase families 57/38, central domain superfamily [IPR028995] 0.5907622739018058 0.3314009783594102 0.7403416259863029 1.0 0.861045334280524 2 O00754 1 +Immunoglobulin E-set [IPR014756] 0.3413616232933685 0.3251907818629554 0.7450366848896102 1.0 0.865262653600403 15 Q13432,A6NIH7,Q9UGP8 3 +Initiation factor 2B-like, C-terminal [IPR042529] 0.5857835218093667 0.3137029463475992 0.7537466627977762 1.0 0.8721794514712393 3 Q9UI10,Q9BV20 2 +Rho GTPase activation protein [IPR008936] 0.4094437257438501 0.3111179294437732 0.7557109713515866 1.0 0.8723273666877366 6 O15031,Q9H0H5,Q14C86,O00459,P46940 5 +EF-hand domain pair [IPR011992] 0.3226443615168649 0.2829523873560549 0.7772133354327573 1.0 0.8853149504329969 50 Q8N163,Q02818,O95202,P80303,Q14257,Q9BRK5,P41208,O95302,O75746,Q9NWM8,Q9UJS0 11 +Lamin tail domain superfamily [IPR036415] 0.55728799919922 0.2486715441899431 0.8036148619609251 1.0 0.9088501415034272 3 P20700 1 +NAP-like superfamily [IPR037231] 0.5501759833381913 0.2337293807203915 0.8151950769089915 1.0 0.9132492017258748 3 P55209 1 +PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946] 0.5445736434108582 0.226946762610578 0.8204651392816438 1.0 0.9180705327650902 2 Q9NZC3 1 +ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121] 0.5405600471199137 0.2143779384901975 0.8302523442858971 1.0 0.9257508533704252 3 P06576 1 +Phosphoribosyltransferase-like [IPR029057] 0.3647593349325349 0.1668704151402494 0.8674720120182386 1.0 0.9549482714971954 6 Q06203 1 +von Willebrand factor A-like domain superfamily [IPR036465] 0.3045525311880349 0.1659674162204071 0.8681825925908524 1.0 0.9549482714971954 16 P12956 1 +Ribosomal protein L14 superfamily [IPR036853] 0.5096899224806202 0.1655636916834656 0.8685003227090282 1.0 0.9549482714971954 2 Q6P1L8 1 +PapD-like superfamily [IPR008962] 0.5121163166397358 0.1630179757218372 0.8705042814144057 1.0 0.9553852465306972 3 Q8NHP6,Q9P0L0 2 +HSP90, C-terminal domain [IPR037196] 0.4065934065934085 0.1600420203286062 0.8728479733724555 1.0 0.9564078139605912 4 Q12931,P08238,P07900 3 +Coatomer, gamma subunit, appendage domain superfamily [IPR037067] 0.5019379844961244 0.1540026128515243 0.8776076754066191 1.0 0.9583072317658484 2 Q9Y678 1 +GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266] 0.5040387722132342 0.1500607692877588 0.8807166710221104 1.0 0.960558808449034 3 Q5T440,Q969Y2 2 +Riboflavin synthase-like beta-barrel [IPR017938] 0.4970310483140976 0.139405618814462 0.889129632544648 1.0 0.9642387567550408 3 P16435 1 +Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261] 0.4970310483140976 0.139405618814462 0.889129632544648 1.0 0.9642387567550408 3 P16435 1 +Rhomboid-like superfamily [IPR035952] 0.3952681151952523 0.1373002252416138 0.8907934924058261 1.0 0.9649416394361856 4 Q9GZP9,Q6NTF9 2 +Moesin tail domain superfamily [IPR008954] 0.4894991922455421 0.1285585015360722 0.8977070047147289 1.0 0.9706549931808256 3 P35241,P15311 2 +SWAP/Surp superfamily [IPR035967] 0.3450840879689454 0.1132724878739748 0.9098145283325094 1.0 0.9795265466695188 6 Q8IWZ8,Q8IWX8,Q8IX01,O15042,Q12872 5 +Bcl-2-like superfamily [IPR036834] 0.3752264640562316 0.1015498688348071 0.9191139725208132 1.0 0.9847319005850708 4 Q9BXK5,Q07812 2 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.463974151857831 0.0963864984280703 0.9232136148887182 1.0 0.9861333958923916 3 Q9BYT8,P52888 2 +Ribosomal protein L24e/L24 superfamily [IPR038630] 0.4463824289405695 0.0920173335635597 0.9266842678267944 1.0 0.9875945921821374 2 Q9UHA3 1 +K homology domain superfamily, prokaryotic type [IPR009019] 0.4431524547803603 0.0894520832793585 0.9287226328602216 1.0 0.9875945921821374 2 P23396 1 +K homology domain-like, alpha/beta [IPR015946] 0.4431524547803603 0.0894520832793585 0.9287226328602216 1.0 0.9875945921821374 2 P23396 1 +Galactose mutarotase-like domain superfamily [IPR011013] 0.3668390433096337 0.0882984847901054 0.9296394432157776 1.0 0.9875945921821374 4 O00754,Q16706,P10253 3 +Death-like domain superfamily [IPR011029] 0.3661926308985153 0.087318860005492 0.9304180631610665 1.0 0.9875945921821374 4 Q12955,Q96FV9,Q7Z434 3 +PNPase/RNase PH domain superfamily [IPR027408] 0.3278791701564231 0.0720150913437164 0.942589897879356 1.0 0.9938517236241824 6 Q96B26 1 +Exoribonuclease, PH domain 2 superfamily [IPR036345] 0.3278791701564231 0.0720150913437164 0.942589897879356 1.0 0.9938517236241824 6 Q96B26 1 +tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026] 0.4229402261712273 0.0586326244867935 0.9532447247907754 1.0 0.9959140177985578 3 Q92979,Q5T280 2 +Alpha/beta knot methyltransferases [IPR029028] 0.4229402261712273 0.0586326244867935 0.9532447247907754 1.0 0.9959140177985578 3 Q92979,Q5T280 2 +RNA polymerase, RBP11-like subunit [IPR036603] 0.3779069767441838 0.0564707970197855 0.9549667589919276 1.0 0.9959140177985578 2 O15160 1 +DNA-directed RNA polymerase, insert domain superfamily [IPR036643] 0.3779069767441838 0.0564707970197855 0.9549667589919276 1.0 0.9959140177985578 2 O15160 1 +MIT domain superfamily [IPR036181] 0.313630490956067 0.046509100310234 0.962904480938192 1.0 0.99653167049364 2 Q8N0X7 1 +ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366] 0.3045865633074887 0.0459873326600098 0.9633203463013196 1.0 0.99653167049364 2 P25705 1 +Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162] 0.2803617571059345 0.0451179817985552 0.964013268614374 1.0 0.99653167049364 2 Q5JTZ9 1 +Dimeric alpha-beta barrel [IPR011008] 0.3334410339256894 0.0217873933761458 0.9826175504298889 1.0 1.0 3 Q9BPW8,Q9UFN0 2 +Prefoldin [IPR009053] 0.3071066385897544 0.0215742584713907 0.9827875675157796 1.0 1.0 4 O60925 1 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..99373fc26ca9d91a9bafa192b72aa4c7bfa4e86c --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP synthase-coupling factor 6 superfamily, mitochondrial [IPR036204]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioester hydrolase/BAAT, N-terminal [IPR042490]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "Apyrase superfamily [IPR036258]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Beta-trefoil domain superfamily [IPR036358]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DENN domain, C-terminal lobe [IPR043153]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA glycosylase [IPR011257]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IA, central region, subdomain 1 [IPR013824]", "DNA topoisomerase, type IA, central region, subdomain 2 [IPR013825]", "DNA topoisomerase, type IA, central region, subdomain 3 [IPR013826]", "DNA topoisomerase, type IA, core domain [IPR023405]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DUSP-like superfamily [IPR035927]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Deoxyhypusine synthase superfamily [IPR036982]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FCS-type zinc finger superfamily [IPR038603]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FTO, C-terminal domain superfamily [IPR038413]", "Fe-S cluster assembly domain superfamily [IPR034904]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like [IPR012347]", "Ferritin-like superfamily [IPR009078]", "Ferrodoxin-fold anticodon-binding domain superfamily [IPR036690]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarate reductase/succinate dehydrogenase, transmembrane subunit [IPR034804]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "H/ACA ribonucleoprotein complex, subunit Nop10 superfamily [IPR036756]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-hairpin-helix, base-excision DNA repair, C-terminal [IPR023170]", "Helix-loop-helix DNA-binding domain superfamily [IPR036638]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "I/LWEQ domain superfamily [IPR035964]", "IFT81, N-terminal domain superfamily [IPR043016]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrase-like, N-terminal [IPR017856]", "Integrin alpha, N-terminal [IPR028994]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Lipid transport protein, beta-sheet shell [IPR015819]", "Lipovitellin-phosvitin complex, superhelical domain [IPR011030]", "Longin-like domain superfamily [IPR011012]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex subunit 25, PTOV domain superfamily [IPR038196]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthioribose-1-phosphate isomerase, N-terminal [IPR027363]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "Moesin tail domain superfamily [IPR008954]", "Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily [IPR036522]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nuclear hormone receptor-like domain superfamily [IPR035500]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PCGF Ub-like fold discriminator superfamily [IPR038227]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PH-like domain superfamily [IPR011993]", "PIN-like domain superfamily [IPR029060]", "PINIT domain superfamily [IPR038654]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S1, PA clan, chymotrypsin-like fold [IPR043504]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Putative deacetylase LmbE-like domain superfamily [IPR024078]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RBP-J/Cbf11, DNA binding domain superfamily [IPR037095]", "RGS domain superfamily [IPR036305]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RNase P subunit Pop5/Rpp14/Rnp2-like domain superfamily [IPR038085]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RRF superfamily [IPR036191]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scaffold protein Nfu/NifU, N-terminal domain superfamily [IPR036498]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Set2 Rpb1 interacting domain superfamily [IPR038190]", "Seven-hairpin glycosidases [IPR036026]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Sodium/glucose symporter superfamily [IPR038377]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfatase-modifying factor enzyme superfamily [IPR042095]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Telomere repeat-binding factor, dimerisation domain superfamily [IPR036507]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonine synthase, N-terminal domain superfamily [IPR037158]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transcriptional regulator TACO1-like, domain 3 [IPR026564]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Triosephosphate isomerase superfamily [IPR035990]", "Tryptophan synthase beta subunit-like PLP-dependent enzyme [IPR036052]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UROD/MetE-like superfamily [IPR038071]", "UbiA prenyltransferase superfamily [IPR044878]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-associated protein 1, C-terminal [IPR042575]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vitellinogen, beta-sheet N-terminal [IPR015816]", "Vitellinogen, open beta-sheet, subdomain 1 [IPR015817]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "YEATS superfamily [IPR038704]", "YebC-like [IPR029072]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG13", "ALG5", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL10", "ARL2", "ARL3", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5J", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATRX", "ATXN10", "AURKA", "AURKB", "B3GAT3", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BCAS3", "BCAT2", "BCKDHA", "BCKDHB", "BCL2L13", "BCOR", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C1QBP", "C2CD5", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2A", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPV", "CEPT1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHORDC1", "CHP1", "CHRAC1", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT9", "CNP", "COA7", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCPS", "DCTN1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDC4", "EDF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FIS1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GORASP2", "GOSR2", "GOT1", "GOT2", "GPATCH8", "GPD2", "GPI", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMPDH2", "ING5", "INTS1", "INTS11", "INTS14", "INTS4", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL3", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LYAR", "LYN", "LYPLA1", "LZIC", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED16", "MED25", "MEPCE", "METTL16", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPG", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL4", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKIPSD", "NCL", "NCOA5", "NCOR1", "NDRG3", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAF1", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEK9", "NELFE", "NENF", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF3", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGL", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD6", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PUS1", "PWP1", "PWP2", "PYCR1", "PYCR2", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REPS1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "RP2", "RPA1", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RREB1", "RRM1", "RRM2", "RRP12", "RRP7A", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RTCB", "RTF1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SCAF11", "SCAF8", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC37A4", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMU1", "SMYD3", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPECC1L", "SPEN", "SPNS1", "SPOP", "SPOUT1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STUB1", "STX10", "STX12", "STX3", "STX5", "STX6", "STX7", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "THEM6", "THNSL1", "THOC1", "THOC3", "THOC6", "THOP1", "THYN1", "TIAL1", "TIGAR", "TIMM10", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKT", "TLE3", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMED8", "TMEM14C", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBFD1", "UBIAD1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UFC1", "UFD1", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YKT6", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H13", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZCCHC17", "ZCCHC3", "ZEB2", "ZFR", "ZMYND8", "ZNF148", "ZNF280C", "ZNF281", "ZNF346", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF644", "ZPR1", "ZRANB2"], "leading_proteins": ["AARS2", "ABCB1", "ABCB7", "ABCC1", "ABCD4", "ABHD10", "ACBD3", "ACP2", "ACP6", "ADD3", "ADI1", "AIFM1", "ANK3", "ANKLE2", "ARMC1", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP7A", "ATP7B", "BAG3", "BAG5", "BAG6", "BAIAP2", "BAX", "BCL2L13", "BSG", "CCAR2", "CD47", "CETN2", "CHERP", "COLEC12", "COPG1", "CPT2", "CPVL", "CYB5B", "CYB5D2", "CYP51A1", "DERL2", "DHCR24", "DHPS", "DNAJC10", "EIF2B4", "EMD", "EMG1", "EPHA7", "EPHX1", "ERAP1", "EXOSC8", "EZR", "FARP1", "FDFT1", "FKBP14", "FKBP9", "FLOT1", "FLOT2", "FOXRED1", "FUCA2", "GAA", "GAPVD1", "GATAD2B", "GDE1", "GGCX", "GINS3", "GLA", "GLB1", "GNA13", "GNAI2", "GOSR2", "GSR", "GSTO1", "GTPBP3", "HINT3", "HLA-C", "HMOX2", "HSP90AA1", "HSP90AB1", "IBA57", "IQGAP1", "KEAP1", "LDAH", "LEMD3", "LETM1", "LMNB1", "LNPEP", "LSM3", "LSM5", "MAN2A1", "MAN2B1", "MAVS", "MFSD10", "MFSD8", "MGEA5", "MIA2", "MIA3", "MINPP1", "MOSPD2", "MRC2", "MRI1", "MRPL14", "MSTO1", "MTCH1", "MTCH2", "MTX1", "NAGLU", "NAP1L1", "NENF", "NIPSNAP1", "NIPSNAP3A", "NLN", "NNT", "NPEPPS", "NT5C2", "NT5C3B", "NT5DC1", "NUCB1", "NUCB2", "OCLN", "PABPC1", "PABPC4", "PCYOX1", "PCYOX1L", "PFDN1", "PHB", "PHB2", "PIK3R2", "PLA2G15", "PLXNB2", "PMPCA", "PNPLA6", "POLR1C", "POR", "PPAT", "PPOX", "PPT1", "PPT2", "PRCP", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSME2", "PTGES2", "RACGAP1", "RAPGEF2", "RARS", "RBM10", "RCN2", "RDX", "RETSAT", "RHBDD2", "RINT1", "RPS3", "RSL24D1", "SCO2", "SCPEP1", "SDF4", "SEC63", "SEL1L", "SFSWAP", "SLC16A1", "SLC19A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A40", "SLC25A42", "SLC25A44", "SNX9", "SPART", "SPNS1", "SPOP", "SPOUT1", "SQLE", "SRSF7", "STIM1", "STOM", "STOML2", "STX10", "STX3", "STX6", "STX7", "SUGP1", "SUGP2", "TAF15", "TAP1", "THOC1", "THOP1", "TMED7", "TMX4", "TRAP1", "TSPAN3", "TUBB", "TUBB2B", "U2SURP", "UBQLN4", "UBXN4", "UNC119", "UNC119B", "UQCRC2", "USP47", "VAPA", "VDAC1", "VPS33B", "VPS45", "XRCC6", "ZADH2"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6b2b1d3e31851c6905a093a9239a9bf9fdb4ccf5 --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "P-type ATPase, phosphorylation site [IPR018303]"} \ No newline at end of file diff --git a/interpro_ptm/basic/plot_0.png b/interpro_ptm/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..31c8520b1cbbc772aacd18fb9b2bbd72dae77a4f --- /dev/null +++ b/interpro_ptm/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:548e54e14073d4cd7b9e156fca8c49fdf5fcd23b02d00c54646ac836f9d06701 +size 136433 diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..1d9ad0be62776cb096e2e5c89ef5fca721db4571 --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:13edd7b6828a9b78c911cba156b34d0d3c8f1dd285abc0d8de3925db8ba8343a +size 68236 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2bf935d74d1ad6b648c1c7cff7a089dd6ff1cf9f --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 3.25 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..988e1ca49fd9d8586b1d253e2dbe5295bb0c58e8 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..878eac9562f8d401b9c17388fee5f7227e22df78 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.7049311463738145 1.894560041419152 0.0581507128361031 0.2130889321441932 0.2326028513444127 9 Q04656,P16615,P98194,Q9HD20,P35670,P20020,P23634 7 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..287bfd7316756c4f68d247474ebdbb0b6e04bf11 --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP7A", "ATP7B", "EIF5A", "FASN", "LDLR", "SLIT2"], "leading_proteins": ["ATP13A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP7A", "ATP7B"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..bf782b48154af983078ccbbfb390a571d9d7e0c7 --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7c95e3b54a8f183e3361d4e67e3a6bc45649590560e4843c9798b6c62133ef53 +size 184501 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..3e30a487f578ebed1ee6d5e4012d2948a5c3d59e --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:90713d5d42e563cbc23a58ef13f54450982ce0a1e0a8da2ef00a5fffd6a0b962 +size 146141 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..ca4611034bea3cc595d0bab17df304ecd3259abc --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3331a3685a3cefffbd42168105d387fe85c46847d73304e3401a4723a2cea077 +size 76252 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bff6d78e1a730eb1f0467368c3f5d0adaa6e9fce --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 15 25 3.3156711128906715 0.0009142335245009 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.0004580163913592 0.1675604235637086 0.0523352985295366 2.9874917190946567e-05 1.1113235605961464e-09 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e57835973123df34d204d3f51b7a48cf853b2d18 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 75, + "title": "Average number of proteins per term", + "value": 5.266666666666667 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..65f172a1cd855033198d73519658a6c869465c49 --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e4416254d7dfb85a11d1c9c359b18b137dfb981e --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.7470280292359393 3.3156711128906715 0.0009142335245009 0.0662988658544668 0.0599653568286506 25 O43772,Q86VD7,Q9Y619,Q9H2D1,Q8TBP6,Q9BQT8,Q70HW3,Q9BSK2,Q9NZJ7,Q9UBX3,O75746,Q96H78,P16260,Q9Y6C9,Q9UJS0 15 +Spectrin repeat [IPR002017] 0.509655663084521 0.9266483388876527 0.354109148365632 0.9999999999999942 0.6052840731677442 9 Q8WXH0,Q03001,P12814 3 +HEAT, type 2 [IPR021133] 0.4426935055385882 0.8142775425351823 0.4154859720029367 1.0 0.6774227804395707 13 Q9BU89,Q8TF05 2 +Leucine-rich repeat, typical subtype [IPR003591] 0.4496064970673246 0.7954267571184466 0.4263653004997683 1.0 0.6803701603719706 12 Q96RT1,Q13641,O94813,Q96AG4 4 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..101112714050d7cf7a735fa6097f9fcb902c7fff --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "FG-GAP repeat [IPR013517]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Fis1, C-terminal tetratricopeptide repeat [IPR028061]", "Fis1, N-terminal tetratricopeptide repeat [IPR028058]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hs1/Cortactin [IPR003134]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "Integrin alpha beta-propellor [IPR013519]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PQ-loop repeat [IPR006603]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "ACTN1", "ACTN4", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC1", "ARMC6", "ARMCX3", "ARPC1A", "ASPH", "BARD1", "BCOR", "BIRC6", "BOP1", "BUB3", "CAST", "CDC16", "CDC23", "CDC27", "CDC40", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "COA7", "COLEC12", "COPA", "COPB2", "CORO1C", 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50.63834951456311 1.9310146760091371 0.188342667216329 9.760351579527285 3.939196260509299 1.9786128158557912 0.3017981993827387 2.091175371768076e-07 5.111567422339664e-05 0.0001694771292921 1.1325122383507624e-07 9.558447491165752e-13 +Membrane organization 61 220 3.2833315741775064 0.0010258792541786 62.02427184466019 223.60922330097088 0.9560408776070136 0.5603311757674675 21.467957454898308 21.375973545731355 1.611091026762519 0.4273954777865132 3.852434142123896e-05 0.1086550668492848 0.000558086783449 1.46755965375835e-06 1.5763652125867942e-10 +Cation transport 42 158 3.276363255213311 0.0010515321932795 40.9247572815534 152.4733009708738 1.0106305648473772 0.4693050539746304 15.98502541638414 15.374508146736815 1.5607432077940149 0.4143686874753333 0.0249432479890011 0.0888810791636973 0.0086109576280519 0.0045823733282514 0.0102852539630712 +Monovalent inorganic cation homeostasis 12 30 3.185430811794895 0.0014453866103434 9.014563106796116 27.87378640776699 1.1567920478867002 0.2845186374336156 4.051822262152646 3.607380814764068 1.4117439861533438 0.3149022278800241 0.000253043820741 0.000401649685731 0.0006947605035307 6.238783903159406e-05 8.850050427314066e-06 +Endomembrane system organization 43 150 3.170689191503935 0.0015207776508521 47.08980582524272 169.73058252427185 0.8987911429216844 0.5600148744834964 15.914797198368843 20.49740065572335 1.4161383035869868 0.4170367608227654 0.0071040198953975 0.2845607441622844 0.0820121782494786 0.0129959294650849 1.1021573294787977e-05 +Protein insertion into membrane 13 30 3.0966288966439386 0.0019573474439449 9.861650485436892 27.67718446601942 1.4180388387951812 0.2751856944202687 4.426616888970974 3.3195747527036987 1.508549988584809 0.3318307488597651 2.472883658089222e-05 0.0018472853800074 0.0014732567036546 2.7393573916684325e-05 8.28667164925179e-08 +Cellular monovalent inorganic cation homeostasis 11 28 3.085959125573348 0.0020289671162949 8.191747572815533 25.12378640776699 1.1978511848260835 0.2636491484517694 3.558748260132903 2.9783551257949803 1.4212259473978417 0.3021468238591936 8.06047962028845e-05 0.0002008886603826 0.0003016125361838 1.4349197272756235e-05 5.478593541938059e-06 +Protein transmembrane transport 10 27 3.0341354642664324 0.0024122608686827 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 0.0002846017068054 0.000115947693888 0.0017009652209114 0.0002678672315905 6.470525843091244e-06 +Mitochondrial transport 26 89 3.0333936222681523 0.0024181995164784 26.76456310679612 83.42233009708738 1.9353944346565397 0.260698067067068 11.29934298946582 6.8259418360610375 1.9296757414965091 0.3685496297416806 1.2408261435134372e-06 1.450917938575332e-05 6.692618059919773e-07 2.4174200692442393e-08 2.216000479574193e-09 +Organophosphate ester transport 14 30 3.022727145566153 0.0025050800166064 10.29126213592233 27.364077669902912 1.4948680330369015 0.1889391065154625 4.84293313185659 4.31957284765524 1.6451867819665518 0.2532208690981375 0.0116734382143932 0.0551599902794207 0.0413282647695778 0.0424479309650379 0.0003936097898921 +Ph reduction 6 13 2.940679972008636 0.0032749269324736 4.422330097087379 12.509708737864075 1.1966830084586066 0.1930048880851129 1.91475781321527 1.7851607614701208 1.4167744165903868 0.2497649393583847 3.533798468146991e-07 8.855241383339473e-06 6.418208082332269e-06 3.446945158628824e-06 4.205073922679249e-06 +Protein targeting 28 108 2.9289056183015663 0.0034015769200379 30.48543689320388 111.54126213592232 1.595466660966077 0.3336055854889273 10.683999539888966 11.70327920021055 1.673091584234216 0.3988264387816677 6.06812472864321e-08 0.0001789997777504 3.008901507904801e-05 7.227554503110613e-07 4.316484166543819e-06 +Chemical homeostasis 39 183 2.9268516256133736 0.003424121939987 43.762135922330096 177.7597087378641 0.7082111793088889 0.511106347874914 13.668464281922288 17.87763227716401 1.3204137511810292 0.4179418895476048 0.0035039529912939 0.0002633225511404 8.548427312506777e-05 0.0044579605086261 0.000942282984896 +Regulation of ph 10 23 2.917148842820396 0.0035324715947069 6.890776699029126 20.859223300970875 1.2151699598837196 0.2373503364294603 2.930458126920059 2.7746402510870145 1.4154672965603718 0.2873526492076106 2.816377916155326e-05 0.0001075756277076 0.0001411644236219 3.680912371066755e-06 5.23259107087535e-06 +Regulation of cellular ph 10 23 2.917148842820396 0.0035324715947069 6.885922330097087 20.844660194174757 1.215766922704761 0.2375185297794358 2.9319293283093293 2.765976649626597 1.4143296516981956 0.2875299337708636 1.888840196386407e-05 8.508689216563006e-05 0.0001059830796752 2.189956478285847e-06 2.672510894072328e-06 +Protein localization to endoplasmic reticulum 11 36 2.884530389883416 0.0039199792212696 9.50242718446602 34.50485436893204 0.9935384348474128 0.428255638055916 4.399083524593319 2.6617527855555916 1.1934894982037212 0.3717243536861919 0.0029353788574153 0.0025436512836883 0.0022276957658844 0.0024554723849656 1.4366492032750328e-05 +Protein targeting to mitochondrion 20 49 2.8363883429233603 0.0045626929312461 14.980582524271844 46.067961165048544 1.7767024064550243 0.249920045184344 6.494927942714517 4.708517660750424 1.5433015545903224 0.3384144763122346 2.566926569563043e-06 0.0008162643340865 2.194109410249272e-05 8.327521080072054e-06 1.8984114034648183e-05 +Inner mitochondrial membrane organization 7 23 2.8246603977701263 0.004733075186637 9.985436893203884 20.800970873786408 1.138268089020681 0.2873707765098114 4.6289277788641146 2.4012939531921327 1.609232985153232 0.3229583948801056 0.003633380055843 0.1635258499471353 0.0054315442599267 2.226230744371199e-06 5.121649611699266e-05 +Mitochondrial membrane organization 12 49 2.8162625758276065 0.0048585939484222 16.983009708737864 46.91019417475728 1.283632855732258 0.3380738792929293 7.413069190635445 4.027718639381892 1.6948461264793506 0.367302285357348 0.0013285554982852 0.0108990791164893 0.0023726768380501 3.220936123422926e-06 5.471666537932621e-05 +Establishment of protein localization to membrane 25 88 2.79770838762512 0.0051466555619914 23.133495145631063 87.3616504854369 1.231448880072231 0.4195243824117992 8.397245527204214 9.510228790351464 1.3947369206386535 0.4065372973031916 4.403180528678698e-07 0.0163421355973242 0.0001573496286064 2.163056328212412e-06 1.675203348876896e-07 +Protein targeting to membrane 9 33 2.739939226281608 0.00614505459183 9.03640776699029 34.86407766990291 0.8678999397376299 0.4369909067843477 3.776027437978551 4.807050937156168 0.9685770296783628 0.3476738150633759 0.0001687778645134 0.0707254675278004 0.0584891686146332 0.0015917790382586 0.0125470884313581 +Mitochondrial respiratory chain complex assembly 18 42 2.723364870257825 0.0064620645272446 14.427184466019416 38.300970873786405 1.6683402305651691 0.229838901803248 5.648441561419256 5.588363345618 1.6629328950455762 0.3088219725228932 0.0001687778645134 0.0009257347283437 0.0117389654214918 1.1550137002587494e-05 1.4333048478181703e-06 +Inorganic anion transport 9 29 2.709988612651523 0.0067285518167115 9.900485436893204 25.351941747572816 1.3590123122148194 0.2025490755989976 4.608697956226863 4.352203003870329 1.5972877171217004 0.2769639658120273 2.2915855719864427e-05 0.0043748091677711 0.0044625009891105 5.620809439698452e-06 0.0001052998001008 +Neutral lipid biosynthetic process 2 8 2.693568094993384 0.0070691703538365 2.1067961165048543 6.288834951456311 1.1186547336258812 0.1821371148552785 1.2515048910859687 1.3298556757746482 1.2887117600293918 0.213034599641239 0.0109086979057498 0.0073558029266518 0.0021930786590517 0.0267619345648551 0.1410707299584872 +Intracellular protein transmembrane transport 11 23 2.6835550609432173 0.0072843979199317 7.233009708737864 21.9004854368932 1.450039081018812 0.2247265328975946 3.8281123729210935 2.4627910122818513 1.3220665029303609 0.2876555154826584 0.0073675752544559 0.0196403757049561 0.0705821305211966 0.0044406378118471 4.558635539447923e-05 +Transition metal ion transport 10 16 2.653713178511938 0.0079611465315454 4.70873786407767 14.08980582524272 0.8861898222657586 0.2678437025860737 2.4756329698054333 2.718007722894407 1.3738160036140448 0.271065502827487 0.0815719560401729 1.0 0.1119611835326611 0.0543044475705096 0.0654262733188917 +Endoplasmic reticulum organization 15 46 2.6382331338223213 0.0083339266041295 14.91747572815534 43.67718446601942 1.1418424810127707 0.3725584991544436 6.208589840117394 4.768440325801463 1.6823827875834556 0.3705219831566139 0.042168081475276 0.0514861271532366 0.1682749782688163 0.0368512438420236 5.431164603415837e-07 +Vacuolar acidification 4 9 2.636022596411285 0.0083884145286439 3.4757281553398056 8.922330097087379 1.27407749822917 0.1611429668415415 1.4148632661931722 1.303016071016461 1.4195929612668792 0.2212670077717619 1.0339158095414144e-05 1.3710267859167043e-06 6.043050183903694e-07 5.302129833761715e-05 0.0001429815632908 +Establishment of protein localization to mitochondrial membrane 7 19 2.6164890146038227 0.0088839222958674 5.572815533980583 16.524271844660195 1.1986544459127668 0.291784793504827 2.8501471321161915 2.5441524813639957 1.2232399066733852 0.3232066755573589 8.588426588809346e-05 0.0073558029266518 0.0021930786590517 3.671693537728937e-05 2.980512657152744e-06 +Triglyceride metabolic process 6 13 2.5962427005401545 0.009424946561483 3.4805825242718447 10.771844660194176 0.9779567044833 0.270555786798488 1.9834538010888536 2.3392770219831345 1.099054194056709 0.249087443977639 0.2134543739745593 0.0239365913088697 0.0846927074465841 0.1203869764331773 0.0099411678564375 +Porphyrin containing compound metabolic process 7 16 2.558393021794346 0.0105157169507941 4.91747572815534 16.531553398058254 1.0269348271542438 0.279733852070357 2.276512713100022 2.089380108414912 1.2578863722796805 0.2914421038569487 0.0220828366682075 0.1553991536419083 0.045127039841821 0.0097601039903573 0.0002147363626889 +Vacuole organization 12 47 2.5583432496687 0.0105172223227136 14.220873786407768 51.74514563106796 0.8524122478550634 0.3147425083910056 5.370022076358251 7.439112114793103 1.7567175511320523 0.3563110134355993 0.0178374922695348 0.0064011041353566 0.0173550139352357 0.0130564574399452 0.0383133074429545 +Cytochrome complex assembly 7 13 2.537602563598998 0.0111614657703886 5.339805825242719 11.616504854368932 1.5489281771301031 0.1834582376033618 2.45860248431673 2.439266047793512 1.3189185418401956 0.2620853228235733 0.0204436144926609 0.151306852499084 0.2827159209662828 0.000144725329193 0.0001729005795719 +Vitamin transport 5 10 2.448313351874422 0.0143526771632802 3.587378640776699 7.597087378640777 1.658661901456128 0.1256251915839625 1.8073839707699664 1.6422194495621811 1.0713624000848283 0.1994200282768667 0.063811929472465 0.1093006244161378 0.208984012191681 0.0195244436529747 0.0052134507581354 +Protein localization to mitochondrion 24 62 2.4433640031817654 0.014551052640376 18.37621359223301 58.6747572815534 1.743973973786015 0.2835887708870952 7.329731795051445 5.553888141183353 1.6030721833013164 0.3628376459321563 1.6359698402952086e-05 0.001748605497394 8.22914280876113e-05 5.861217240468368e-05 3.935999247766727e-06 +Entry into host 3 31 2.4312735136860018 0.0150458517317457 7.968446601941747 31.24514563106796 0.6061616104105989 0.3954837799611526 3.566493820193545 3.4119437173329663 1.31706945612869 0.333413728218646 0.076973366344576 0.0734458650364987 0.0616304522136525 0.1885836684813616 0.4735789670016921 +Triglyceride biosynthetic process 1 7 2.426593909175187 0.0152413052337871 1.4757281553398058 5.274271844660194 0.8957176915704722 0.2655240444557116 1.2274740041869927 1.2502497629633054 1.1422343750332298 0.2371147384530898 0.0591475015489903 0.0053672672920639 0.0206800818926893 0.1060727287920157 0.3080842130268088 +Cation transmembrane transport 31 122 2.426369069751264 0.0152507521553157 33.43446601941748 118.4004854368932 1.1701058025505957 0.4085228823574113 14.425169362008605 12.553856783980793 1.6663185381795875 0.4066910074955585 0.0127745925659043 0.0329027153172182 0.0033357135019959 0.0007561599316184 0.0012725535521377 +Sphingolipid metabolic process 14 29 2.4091345647853 0.0159904009307105 12.631067961165048 29.174757281553397 1.3566630100256978 0.1614907042591146 4.986857078326301 3.461093559903884 2.232073980338918 0.2503191978902473 0.0002115805305972 0.3654998372428625 0.0632302441478985 0.0004398170742491 0.0018998026291165 +Protein transmembrane import into intracellular organelle 7 14 2.3972037421983186 0.0165207346368401 4.951456310679611 13.45631067961165 1.503963012554726 0.1758225015375162 2.735521961789203 1.4944992929031071 1.2360761671845495 0.245991671368161 0.0145822304975559 0.0090330503435184 0.03403446937649 0.0352396407582777 0.0027845492980534 +Response to increased oxygen levels 2 9 2.38254644341814 0.01719336305029 1.9563106796116505 8.939320388349515 0.9100937072347148 0.3197058737817761 1.2933864561055997 1.001798152387997 1.0059424935454593 0.2746313949658078 0.0046437067491223 0.0001122733832082 0.0008978593047678 0.01180448121602 0.0701952648708137 +Establishment of protein localization to organelle 25 169 2.346110705643015 0.0189704719154777 40.4247572815534 180.123786407767 0.6176411706537287 0.628535284461401 14.116769229706104 14.40373863390995 1.0281809729691214 0.3983757503188239 0.0035193414149697 0.0014701182407849 0.0023853821188681 0.0060826753237184 0.0082796779353711 +Regulation of lysosomal lumen ph 4 7 2.342246220985755 0.0191680647904732 2.3567961165048543 5.58252427184466 1.1719038900849827 0.159040563248536 1.2351555175791742 1.4280428037740598 1.4707016211600112 0.2132438131163355 0.0019745890336275 0.0022827689145391 0.0003712110430798 0.000371706641515 0.0005289198821125 +Chloride transport 3 13 2.3297515401425124 0.0198192867616548 4.33252427184466 12.12621359223301 1.0302584084066435 0.2341882174183942 2.3624510960969567 2.26059366569241 1.2797232968088257 0.2563105728143979 0.002374895513008 0.1471951297158956 0.0405463165390607 0.007920049564759 0.07392944267488 +Glycerophospholipid catabolic process 2 10 2.313275238231558 0.0207075112092065 2.216019417475728 7.563106796116505 0.8419758607208171 0.2558936783676348 1.405411068501889 1.391164232085279 1.2384126210044872 0.2497846504551273 0.0023996235659409 0.0742352733278267 0.0102498345034834 0.0062267265321947 0.0397387250697101 +Cellular ion homeostasis 32 92 2.3083778055253994 0.020978132336032 24.48543689320388 87.34708737864078 0.921352068115914 0.4223079442129951 9.212290310790763 8.933596252465952 1.5207794649628892 0.4002972861975121 0.0076989939570692 0.0096723767157603 0.0013083403638517 0.0026413619474206 0.0001440391577151 +Vitamin transmembrane transport 3 7 2.306679312010488 0.0210727043987086 2.9344660194174756 6.094660194174757 1.6910321805591797 0.1136175735100163 1.344920850275403 0.8913122381585616 1.0580472895861666 0.1862049292817703 0.0268439946301445 0.0697581245313758 0.1362380906066266 0.0051503840765812 0.0048822579474643 +Nucleotide transport 8 16 2.299149919974965 0.0214964276474658 6.189320388349515 13.405339805825244 1.3859091987706234 0.2148450774807873 3.399469193898354 2.266957807297256 1.34942986946681 0.2785977875693559 0.0734939527005626 1.0 1.0 0.1300982938321277 0.0001788650990257 +Phospholipid transport 5 13 2.2873268456245297 0.0221767526759435 4.038834951456311 13.844660194174756 0.8595089147672731 0.22382450694892 1.931709490395295 2.5542930986961077 1.4491821424024287 0.2459407475876757 0.0576324875298074 0.0248381956323572 0.0132042256106822 0.1257511849434855 0.1000707214680032 +Anion transport 35 78 2.281413364416802 0.022523997952516 26.953883495145632 69.53155339805825 1.854216838065017 0.2425457725148559 12.138973160217668 8.434296289414672 2.014686633079497 0.3448588040224388 0.0001761227395126 0.0710204091336867 0.129783031482388 2.757011435594295e-05 7.849375238217139e-09 +Establishment of protein localization to endoplasmic reticulum 5 21 2.269362465330826 0.0232462927713936 5.657766990291262 22.070388349514563 0.461449325411609 0.540521677773824 3.0958573736115995 1.7687681096977308 0.870924743015325 0.3289535305239591 0.0204436144926609 0.0115082778780227 0.0428134756181982 0.0088087297166582 0.0053527619374205 +Carbohydrate derivative transport 11 22 2.247733149611904 0.0245932108650932 7.924757281553398 17.024271844660195 1.3665639952580566 0.1869571280171947 4.210097511648942 2.624454303682939 1.5541767319140831 0.2467993156006303 0.0446798083571155 0.1991580424676108 0.3622612502953293 0.0998367022916053 0.0014891058006406 +Response to arsenic containing substance 2 12 2.243241754598698 0.0248812290793261 2.8689320388349513 12.75728155339806 0.6381797187741653 0.4824630798477249 2.146866270122349 1.3032149895842966 0.7673368711275027 0.2943437667902449 0.0785007730839361 0.1221118561195742 0.0279813079733609 0.1383652025719425 0.1410707299584872 +Negative regulation of calcium ion transport 1 8 2.2388599339649566 0.0251650311351834 2.378640776699029 8.815533980582524 0.865801675063994 0.3348216966365627 1.767376998119782 1.5264501163101216 0.996781239251156 0.2731835761958332 0.0941229184977135 0.0090330503435184 0.03403446937649 0.1637924032376012 0.4315495391205481 +Tetrapyrrole metabolic process 9 19 2.2349808819254853 0.0254186038904518 5.652912621359223 19.283980582524272 1.0342508202848784 0.290677507336007 2.6828141040028877 2.549402305664568 1.2308389507353266 0.2976223887279709 0.0399573695699691 0.1913705796369965 0.0678620701894922 0.0213813720021448 0.00110124435718 +Cellular response to arsenic containing substance 1 7 2.2341611176939447 0.0254724737839124 1.5800970873786409 8.160194174757281 0.59082546149262 0.4433212212071914 1.5219724013838232 0.8805161555361953 0.8678314304321456 0.2799713330796864 0.0339972376759384 0.0786913117950012 0.0115435449528709 0.062605312422627 0.1985866733922443 +Protein insertion into mitochondrial inner membrane 3 8 2.229591898851336 0.0257745481626547 2.45873786407767 5.665048543689321 0.6692509200083531 0.3406754428009103 1.501050234026552 1.645659707056692 1.2686438529444872 0.3125184360343283 0.0009918498188417 0.0561990347849709 0.0057815105752346 0.000142755965642 0.0001575214550341 +Regulation of blood pressure 5 17 2.2260745731536566 0.0260091867634557 5.762135922330097 17.737864077669904 1.3077123393993415 0.1882731913471478 2.2751770017499977 2.3871059987956724 1.372929386780725 0.2480453688154592 0.0031682161674039 0.0315268496209905 0.0023751027082345 0.0026843919056765 0.0065824357934952 +Proton transmembrane transport 11 47 2.223565390267999 0.0261776992992748 14.28640776699029 43.01699029126213 0.7821394801431882 0.3918912894345224 6.076814900000799 3.1076483585332 1.5710697941383835 0.3739424994204808 0.0231678869200826 0.0748187401998431 0.0131034302652722 0.0019595403906339 0.0018998026291165 +Sterol homeostasis 6 12 2.221086470194603 0.0263451052450505 3.2597087378640777 11.594660194174756 0.7425754872590924 0.2773502445350785 1.6018884221780605 1.6170423171351411 1.3033948892752858 0.2615762483252933 0.0274187927150404 0.0142466262053111 0.0058560324261939 0.063688713570506 0.0353817250131281 +Phosphatidic acid metabolic process 1 8 2.216298481039872 0.026671066995678 2.2233009708737863 6.235436893203883 0.8816881639607732 0.2856229767394486 1.614148841412113 1.5439850574626743 1.1927985254107716 0.2824496640110863 0.0734939527005626 0.0068317681715133 0.0260710687649276 0.1300982938321277 0.1298078118605267 +Outer mitochondrial membrane organization 1 5 2.2146711320126045 0.0267826457011819 1.4296116504854368 4.956310679611651 1.1531610290328034 0.2630141305877053 0.9963023114429655 0.2044029443827893 0.89744850896642 0.2676384061848394 0.0028631449281781 0.0238038053541035 0.047623940504538 0.0055694485300755 0.0213301790272909 +Cellular homeostasis 49 147 2.2039345237462444 0.0275289491682597 35.03155339805825 140.69660194174756 0.4666088113804902 0.5685618966047314 11.62423291193178 14.777892439656425 1.1736922314243927 0.3887657095146841 0.1148161737813265 0.0513484222325217 0.0214821273088445 0.0898065941568243 0.0142419171556769 +Macromolecule depalmitoylation 2 5 2.199421100508843 0.0278479936378039 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0009918498188417 0.0014481500629001 0.0057815105752346 0.00262770885776 0.018020673376298 +Mitochondrial atp synthesis coupled proton transport 3 12 2.19150288589904 0.0284154211313008 3.9927184466019416 10.769417475728156 0.5022502301293951 0.29867761594221 2.4440229028906213 0.8937412640542226 1.3849431163992842 0.2834040324316194 0.0378207561175528 0.0032958763634803 0.012905013470629 0.0693365470158766 0.0097510399506001 +Glycoside catabolic process 2 5 2.1854277326910267 0.0288574993169368 2.995145631067961 5.604368932038835 0.914408298188202 0.1915126053981477 1.4021397407455505 0.554137429771367 1.5051386650706404 0.245673751384095 0.0002656754373321 1.0 1.0 0.0007187465088185 0.0053031795330487 +Iron ion homeostasis 3 18 2.179814004822801 0.0292712513925079 4.468446601941747 17.140776699029125 1.0306963602610326 0.26770320823289 2.1032740346004313 1.762496954108992 1.1437451534606062 0.2692749918411525 0.0114109532240053 0.0018472853800074 0.0014732567036546 0.0345596402774107 0.1000707214680032 +Calcium ion regulated exocytosis 2 9 2.172494481398731 0.0298183854446867 2.5825242718446604 8.966019417475728 0.2490819455283515 0.6155759649447953 1.894162067704679 1.2709642695136016 0.7341501796400864 0.2903992185898027 1.0 1.0 1.0 0.544318157098314 0.2015708610705285 +Atp synthesis coupled proton transport 3 13 2.166703591458288 0.0302574625778311 4.067961165048544 11.769417475728156 0.4798560195228825 0.3249136059986872 2.5150503707528173 0.8937412640542226 1.340203957668315 0.2941072770431484 0.0459284510874455 0.0040679264544396 0.0158256043387446 0.0834574734746242 0.0143001062154138 +Negative regulation of calcium ion transmembrane transport 1 6 2.166660749672634 0.030260731521057 2.1067961165048543 7.601941747572815 0.9433101814663925 0.3101119054926485 1.594362771690279 1.170758660555987 1.028728108691548 0.2750664841729511 0.0417999766536677 0.0036723611473879 0.0143328298354406 0.0762921742488627 0.2348875720984273 +Calcium ion import 2 14 2.1597352155298317 0.0307931733792643 4.516990291262136 12.686893203883496 1.0417029373125424 0.2391249176108038 2.3196506830054986 1.9148178088324157 1.3383409214307818 0.27915846054651 0.1334837777517871 0.1635258499471353 0.0498890213657128 0.2256009180273313 0.2668248172965894 +Ion homeostasis 35 107 2.159412546706533 0.0308181753705121 28.021844660194176 105.69174757281552 0.8349951537384392 0.4299135801564597 10.40966729997928 11.411952082971936 1.4722934854811005 0.3963893325418664 0.0124248053377853 0.0048934230764703 0.0013956128269463 0.0068813031757395 0.0007521744468236 +Mitochondrial electron transport cytochrome c to oxygen 3 6 2.156223521196167 0.0310662157440118 2.6189320388349513 6.021844660194175 0.7576771538928655 0.3133819177040797 1.4641113893518565 0.9306060741204804 1.2097595052740109 0.2966582872605096 1.0 1.0 1.0 0.00262770885776 0.0019884945269669 +Lysosomal lumen acidification 2 5 2.1541823467426866 0.0312258747088221 1.9077669902912624 4.094660194174757 1.0430284513288333 0.1731957374320673 1.0102570393282595 1.1504623937719378 1.495459416196642 0.2154807950267566 0.0007534171574726 0.0012105019492812 0.0001384716540127 0.0020064706347618 0.0013781701696679 +Membrane lipid metabolic process 17 40 2.152985810840477 0.0313197936972156 15.813106796116504 37.71116504854369 1.423850539998867 0.1808469841706369 6.252884620395072 4.742042041181393 2.289538519382486 0.2724480316274368 0.0002243425346026 0.4409382257745535 0.1111181143510491 0.0006520562274492 0.0019842175144136 +Amino acid transmembrane transport 9 15 2.1264401491580123 0.0334666277447699 6.213592233009709 14.228155339805824 0.7890307267204019 0.3318923540291705 3.493823914060917 1.9561661273054285 1.3497309258640615 0.3227865040448734 0.5596785998836412 1.0 1.0 0.3157753203157507 0.0070893533545687 +Protein insertion into er membrane 5 12 2.1126060405842884 0.0346345012750803 4.451456310679611 12.691747572815531 0.9645901040516046 0.3077872373135509 2.16101217194965 1.431147904526304 1.1733171268605926 0.305304417896891 0.0546082347726425 0.1006582454154426 0.1933613304033528 0.0983610682747182 0.0004867641084232 +Adult locomotory behavior 3 14 2.1078160459155666 0.0350469043475327 3.95873786407767 14.822815533980584 0.7389907423501648 0.3383620981823156 1.833016072372531 1.4878680371825237 1.1254592435779416 0.2897204029443448 0.0048303145699814 0.1755724648168266 0.0067632743899401 0.0155108289838298 0.1274755097437061 +Pattern recognition receptor signaling pathway 7 25 2.107159501040506 0.0351037561200127 6.783980582524272 30.48543689320388 0.3893983283533752 0.5277852242642479 3.0860531364168065 4.421623999132768 0.9404779897396882 0.3335139395352661 0.2813804815604027 0.4043878907472013 0.2786826950506385 0.482172538788556 0.1482732403897816 +Fatty acid transmembrane transport 4 8 2.106799010225368 0.0351350053380301 2.3519417475728157 6.720873786407767 1.487456141723218 0.1763040127694548 1.5547987465385102 1.1092073674791965 0.7935702169981724 0.2103298472796338 0.0174535696320652 1.0 0.1105474823156849 0.00262770885776 0.0019884945269669 +Nadh dehydrogenase complex assembly 11 31 2.100124883204826 0.0357178569412002 9.266990291262136 26.96359223300971 1.1245271541492263 0.3013677937017552 4.122702675359976 4.029157649894909 1.4460543016521823 0.3224564676521605 0.0166605968009377 0.0025436512836883 0.0177960185678587 0.0120464435451714 0.0003655904724143 +Immune response regulating signaling pathway 12 46 2.0905387703697653 0.036569429446958 11.87135922330097 55.80339805825243 0.3432268025292578 0.6206637713853932 5.259337982730306 7.360527636927723 0.8133581401956841 0.3313585351560056 0.3206183159521289 0.2801791252263636 0.1599930923503212 0.608151722626576 0.2560854822741795 +Mannosylation 5 8 2.088861674956983 0.0367201766356697 2.6262135922330097 6.966019417475728 0.6104715271961744 0.3620085753936749 1.5520397580890246 1.435949900284761 1.1183031747274563 0.2897179829421447 0.3754602418326228 1.0 1.0 0.4846912912858679 0.1410707299584872 +Regulation of pattern recognition receptor signaling pathway 5 16 2.079880425695451 0.0375365018464668 4.691747572815534 19.70873786407767 0.80673262224624 0.4173389113947272 2.517825740704142 3.173406084005513 0.919675411949683 0.3119180769844089 0.2903299991295317 0.2588687133858448 0.4548903476361624 0.445381784247055 0.0792626216408109 +Protein import into mitochondrial matrix 5 11 2.0796849523804006 0.0375544391853264 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 0.0268439946301445 0.0022827689145391 0.0090253131212995 0.0498779046475234 0.0048822579474643 +L alpha amino acid transmembrane transport 7 11 2.076938908888103 0.0378071980359042 4.480582524271845 10.533980582524272 0.7590361902351016 0.3223730555033793 2.606398335255894 1.1951807271273862 1.273814103695318 0.3116596719827348 1.0 1.0 1.0 0.5553918894123164 0.0045924061823516 +Neurotransmitter secretion 3 17 2.070430582747427 0.0384120403827057 4.878640776699029 19.800970873786408 0.4739837619437216 0.5379742436571602 2.5178643472114657 2.5013004441236206 0.8040908235944773 0.3018218439933647 0.7615434466089132 0.3274019772455256 0.552149589688304 0.5946863363415549 0.568363206821541 +Protein quality control for misfolded or incompletely synthesized proteins 3 12 2.063672930923952 0.0390487375494013 2.79126213592233 12.0 0.5975496500899943 0.4916109553523294 2.034918800227117 1.0096620601608022 0.8606428606135228 0.3201479866678081 0.0785007730839361 0.0073558029266518 0.0279813079733609 0.0267619345648551 0.0397044670530444 +Organic acid transport 24 50 2.057875343970391 0.0396021011212803 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 0.0095316752926836 1.0 0.3851788136583873 0.000119244422606 6.494888416187712e-07 +Negative regulation of transmembrane transport 4 18 2.0572228438348152 0.0396647951316564 4.915048543689321 20.038834951456312 0.539232326403696 0.5077941070021844 2.6236539308948164 2.892649976298608 0.8428552268580063 0.3052620790205636 0.0983732565949483 0.037759654532188 0.1279708837725801 0.2020945775525867 0.1985748090604032 +Nerve development 1 6 2.0567847688335874 0.0397069338281421 1.5679611650485437 7.463592233009709 0.9323166733630548 0.322181793723066 1.371606215406715 1.1303984643014222 0.9327393846140116 0.2711478939504144 0.1757749360267854 0.1913705796369965 0.0678620701894922 0.2887846572413305 0.637323462105345 +Amino acid transport 11 20 2.0521628719443155 0.0401538364205313 7.771844660194175 19.75 0.8410032854505353 0.3449280742441291 4.117377746800764 3.003739578643708 1.287399790463736 0.3206698223659758 0.3349491447838933 1.0 1.0 0.0859135005289206 0.0058898561186024 +Cellular response to increased oxygen levels 1 6 2.049690229672719 0.0403946690501189 1.6504854368932038 6.385922330097087 1.138869139630967 0.2726341581961526 1.2184562719610088 0.8029653015671253 0.9206381175249092 0.2739573544488438 0.0174535696320652 0.0014481500629001 0.0057815105752346 0.0328731354880699 0.1125747569923622 +Lysosomal protein catabolic process 2 9 2.048875147903358 0.0404743250534858 2.6941747572815533 6.587378640776699 0.838918419522322 0.2080383809566978 1.5899151374262637 1.8707342212441815 1.5239608036504366 0.2420459791980847 0.0378207561175528 0.0032958763634803 0.012905013470629 0.0087554356838108 0.0539281835546241 +Protein catabolic process in the vacuole 2 9 2.048875147903358 0.0404743250534858 2.70873786407767 6.618932038834951 0.8383076008345888 0.2101105309103242 1.6017652153393662 1.88837291272598 1.5176899437744062 0.242508547144668 0.0459284510874455 0.0040679264544396 0.0158256043387446 0.01180448121602 0.0701952648708137 +Regulated exocytosis 5 32 2.0293448045727223 0.0424231827659349 9.385922330097088 34.342233009708735 0.5889869251407832 0.528096964379338 3.868480531815476 4.573760415025692 0.9122431884356956 0.3457208176316948 0.6260674201758081 1.0 0.6980596213140103 0.3425620879071548 0.380844976353619 +Homologous chromosome pairing at meiosis 4 9 2.02856091540173 0.0425030328973117 2.4975728155339807 8.245145631067961 0.965829654578573 0.3348869860078453 1.4047402178514554 0.97323438747629 0.9242483632276672 0.2995534430572119 0.0459284510874455 0.0919337377678228 0.1774332758731671 0.0834574734746242 0.0701952648708137 +Endoplasmic reticulum membrane organization 5 10 2.0250990243332936 0.0428571970827669 3.5679611650485437 8.12621359223301 0.656874598832497 0.271683145803182 1.813579499342004 1.2879547393790816 1.532817064292788 0.2945772195616556 0.2026771210299193 1.0 1.0 0.2731207001200411 1.6279070379868977e-05 +Nucleotide transmembrane transport 6 11 2.019613650950546 0.0434234780631936 4.029126213592233 9.24271844660194 1.3657020532080593 0.1972377481261837 2.230443861436908 1.484326001257553 1.1744026177454787 0.2553979780962895 0.0303360476395803 1.0 1.0 0.0561137872346343 0.0007388687073799 +L amino acid transport 7 12 2.016186485609739 0.0437804790604381 5.114077669902913 11.91504854368932 0.7755289387861473 0.3283794523692901 2.998235059113201 1.3256494094845783 1.3058948249973923 0.3189923022900864 1.0 1.0 1.0 0.5661975770404395 0.0053527619374205 +Calcium mediated signaling 5 16 2.0115677431978365 0.0442655225660972 4.538834951456311 18.50242718446602 0.6092287356409146 0.5038251477928647 2.523856388514679 2.605538151751357 0.8029171469877773 0.3120022623859673 0.4212819300555683 0.3306605597140526 0.1926825508424764 0.6013150674679382 0.5780515197764531 +Negative regulation of ion transmembrane transport 3 14 2.007886046199681 0.0446554023065579 3.851941747572816 15.769417475728156 0.5591127282390159 0.4901790245134628 2.193308693671018 2.0873490063373943 0.8555485550788116 0.3017041398323139 0.1819837603944453 0.0196403757049561 0.0705821305211966 0.2978006616879862 0.1732034237667374 +Inorganic ion transmembrane transport 41 118 1.986698352507871 0.0469558345097125 32.300970873786405 111.99514563106796 0.9881513097876132 0.4268253140664947 13.185263141323642 11.586314982845243 1.7161030277526947 0.4113555760685328 0.0347698006970898 0.0811245339020894 0.0179345442445998 0.0016509709005717 0.00466776509866 +Pigment metabolic process 10 27 1.9784417800085037 0.0478788903823867 6.730582524271845 27.429611650485437 0.7330558837492486 0.3938325994367372 3.1680652652278396 2.973572406869117 1.1788232115476622 0.3357800616079686 0.0691272889323803 0.2333020504203794 0.0995728547031488 0.0438041643494559 0.0012031940780095 +Sarcoplasmic reticulum calcium ion transport 2 6 1.9700301229658328 0.0488349183427263 1.9563106796116505 7.322815533980583 0.6468881172758483 0.4186906915304785 1.3230715882937036 1.363591714565082 0.9330202288701288 0.2915813242092217 0.0378207561175528 0.083126337411673 0.012905013470629 0.0693365470158766 0.0539281835546241 +Chemokine production 2 8 1.963501587726328 0.0495879201746936 1.8810679611650485 8.337378640776699 0.9152793985046536 0.327029475914965 1.2820382835273771 1.4780796128991345 0.9350060766690576 0.2657366976150246 0.4276775695775323 1.0 0.2685353106225043 0.544318157098314 0.2015708610705285 +Cell recognition 2 18 1.962728963843724 0.049677675762676 5.29126213592233 22.859223300970875 0.9056944851933356 0.3618031966115522 2.859598274322472 2.538937048941188 0.9847101891513528 0.3060121099700091 0.0881322466080071 0.0345877004093447 0.0212914346042941 0.1835520270988697 0.3438081646501767 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d8df3afd2bfd0a68f075b15a105155a44ce24b4b --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 6410, + "title": "Average number of proteins per term", + "value": 18.20436817472699 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e7a3b054be42fef9ff800c1d6df62f8f282b2857 --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b472cd9e3dbc24c1b5e86052d0285b100c3738ee --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1597 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transmembrane transport 0.5825507410164273 4.942238805074664 7.723053522899664e-07 0.0049382457930068 0.0040622315656179 224 O43615,P00846,Q99595,O14678,Q4KMQ2,O60830,P35670,P21796,P45880,Q70HW3,Q9Y584,Q9C0H2,O43808,O14925,P78417,Q8WTV0,Q8NHS3,Q9NS69,O75964,Q8IXU6,Q13423,O43772,P98194,Q9HD20,P08183,Q9UDW1,O75844,Q6P4A7,Q9UHG3,Q9BSK2,Q8TBP6,P41440,Q03518,Q96NB2,P31751,P0CG08,O95831,P27105,Q7KZN9,P51790,Q9BQT8,Q9UBX3,P53985,Q96H78,P13073,Q16625,P20674,Q9Y6M7,P38435,P30825,O75298,O95202,Q9HC07,P23786,P16615,Q9H2V7,P00403,Q13586,Q9UJS0,Q86VD7,Q9UGP8,Q9UJZ1,Q15388,Q8TB61,Q9Y619,O75381,Q96PU5,O75746,Q15629,Q9Y277,P50416,Q9H2D1,P06576,Q14728,O00400,P33527,O75915,O75027,Q15758,P16260,P50570,O95563,P20020,P60602,Q8TDW0 85 +Ion transmembrane transport 0.5485522099887072 4.844788387141424 1.2674669471496805e-06 0.0080915539849334 0.0040622315656179 163 P00846,Q14728,P16615,Q96NB2,P00403,P0CG08,P21796,P45880,Q70HW3,O00400,P27105,P33527,Q13586,Q9C0H2,O75915,P78417,Q7KZN9,Q9UJS0,O75027,Q86VD7,P51790,Q15758,Q9UJZ1,Q9BQT8,O75964,Q8TB61,Q9UBX3,P53985,Q13423,P13073,O43772,Q9Y619,P50570,P98194,Q9HD20,O95563,Q96PU5,P08183,O75746,P20674,Q9UDW1,Q9Y277,O75844,Q9Y6M7,P30825,Q6P4A7,O95202,Q9HC07,Q9H2D1,P06576,Q9UHG3,P41440 52 +Mitochondrion organization 0.497828489205367 3.958939005624139 7.528345827489957e-05 0.3828141797699721 0.1608556558473708 193 Q99595,Q96A26,O60830,P21796,P45880,O95831,P03886,Q9Y584,O43676,Q9H061,P14406,Q9UDX5,Q9Y2R0,Q9NS69,Q9UJZ1,Q69YU5,O14737,Q99536,Q15388,Q53H12,Q5XKP0,Q9NQ88,P62072,Q13505,Q8N163,Q8N4H5,O95168,O75153,P35914,P51572,P55786,Q9NVT9,O00203,Q9NUQ9,Q6DKK2,Q5T9A4,O75431,Q13794,Q9Y6C9,O96000,Q10713,O95202,O43819,Q96TA2,Q9BSK2,Q9P0J0,Q15070 47 +Organic acid transmembrane transport 0.7101598248536664 3.598795300875462 0.0003196946970147 0.8712098114099798 0.2687068745597027 34 Q96NB2,P31751,P33527,O75915,Q9UJS0,Q15758,Q9BQT8,Q9UBX3,P53985,O43772,Q9Y619,O95563,P08183,O75746,P50416,P30825,Q9H2D1,P23786,Q8TDW0,P41440 20 +Localization within membrane 0.4546066411200645 3.5057061749045775 0.0004553976445844 0.9460535709269374 0.2687068745597027 168 Q9Y2D4,O43752,O43681,P46379,Q9BRK0,O75955,P07602,Q5VZ89,P31751,Q9P0I2,Q8N2H4,Q9HD45,Q9NZJ7,Q9Y584,P27105,Q13641,O75915,Q5BJH7,O00264,Q15363,P49458,Q9Y4G8,Q9NPA0,O15400,Q9BTX1,Q5W0Z9,Q9UGP8,Q9NS69,O14737,O15118,O60725,Q96A33,Q53H12,P62072,P23634,Q07812,P50570,P98194,Q13277,Q4J6C6,Q9HD20,O00203,O95429,Q15629,Q9Y3D6,Q9BXS4,P60602,P43307,O14976,P35613,Q9NV70,Q9P0J0,Q9UNK0,Q7Z3B4,P41440,Q15070 56 +Anion transmembrane transport 0.6912043237717945 3.4454337289105355 0.0005701437509215 0.9741556603061594 0.2687068745597027 49 Q4KMQ2,Q96NB2,P21796,P45880,P33527,O75915,O43808,Q9UJS0,Q86VD7,P51790,Q15758,Q9BQT8,Q8TB61,Q9UBX3,P53985,Q9Y619,O95563,P08183,O75746,Q9Y277,Q9Y6M7,P30825,Q9H2D1,Q9UHG3,Q8TDW0,P41440,Q14728 27 +Ion transport 0.4687657821251781 3.3989813084994673 0.0006763733859562 0.9869245688172614 0.2687068745597027 215 P00846,O15173,O43681,P16615,Q14728,Q96NB2,P07602,P00403,P0CG08,P21796,P45880,Q70HW3,O00400,P27105,P33527,Q13586,Q9C0H2,O75915,P78417,Q7KZN9,Q9UJS0,O75027,Q86VD7,P04899,P51790,Q15758,Q9UJZ1,Q9BQT8,Q08722,O75964,Q8TB61,Q9UBX3,P53985,Q13423,P13073,O43772,Q9Y619,P50570,P98194,Q9HD20,O95563,Q96PU5,P08183,O75746,P20674,Q9UDW1,Q9Y277,O75844,Q9Y6M7,P30825,Q6P4A7,O95202,Q9HC07,P06576,Q9H2D1,Q9UHG3,P14174,P41440 58 +Lytic vacuole organization 0.7793043524246587 3.3960353647092387 0.0006836952542585 0.9875244606727636 0.2687068745597027 23 Q14108,P50897,Q8NHS3,Q9HC07,O75503,P54802,O00203,P11117,O14773,Q8N511 10 +Mitochondrial transmembrane transport 0.6689360651647649 3.290518422289505 0.0010000295344723 0.9983605535813728 0.2687068745597027 57 O43615,P00846,Q99595,Q96NB2,O60830,P21796,O95831,O75027,Q9UJS0,Q9UJZ1,Q9BQT8,O75964,Q15388,O43772,Q9Y619,O95563,O75746,P50416,P60602,O95202,Q6P4A7,P06576,Q9H2D1,P23786,Q9BSK2 25 +Membrane organization 0.4630849044690699 3.2833315741775064 0.0010258792541786 0.9986111252061182 0.2687068745597027 220 O43752,O43681,P16615,P46379,Q00765,Q9BRK0,O75955,Q9P0I2,P31751,P45880,P04114,Q9Y584,P33527,Q12981,O43760,Q15363,Q9NPA0,P51790,P50897,O15400,Q9NQC3,Q15392,Q9NS69,Q9Y5X1,Q86XL3,O14737,O15118,Q9BSR8,Q96A33,Q53H12,Q5XKP0,P62072,Q13505,Q8N1F7,Q5JRA6,P61916,P50570,P98194,Q13277,Q8NHH9,P50402,P08183,O00203,Q15629,O14653,O75431,Q9UQB8,Q13794,Q96CP7,O75844,P60602,O95249,O14976,O95202,Q9P2W9,O60499,P20700,Q9P0J0,Q9UNK0,P41440,Q15070 61 +Cation transport 0.4475781303276168 3.276363255213311 0.0010515321932795 0.9988219181071688 0.2687068745597027 158 P00846,O15173,P16615,P02786,Q4KMQ2,Q96NB2,P00403,P35670,P21796,Q70HW3,O00400,P27105,Q13586,O43808,O75027,P78417,Q7KZN9,Q86VD7,P04899,Q9BXP2,P51790,Q15758,Q9UJZ1,O75964,P23634,Q13423,O43772,P13073,Q9Y619,P50570,P98194,Q9HD20,Q96PU5,P20020,P20674,Q9UDW1,O75844,Q9Y6M7,P30825,O95202,Q9HC07,P06576 42 +Monovalent inorganic cation homeostasis 0.674663001627506 3.185430811794895 0.0014453866103434 0.9999059449522544 0.2687068745597027 30 Q9Y6M7,P04899,P51790,P50897,Q93050,Q9HC07,P06576,O75503,P0CG08,Q96PU5,Q9Y487,Q8N511 12 +Endomembrane system organization 0.4700854817807123 3.170689191503935 0.0015207776508521 0.9999420311451144 0.2687068745597027 150 O43752,O43681,Q14108,P46379,P16615,Q00765,Q9BRK0,P40616,Q4KMQ2,Q9UL15,O75955,Q9P0I2,P31751,Q12981,O94901,O43760,Q15363,Q9NPA0,P51790,Q9UP83,Q9NQC3,O95197,Q9Y5X1,Q86XL3,Q9BSR8,Q96A33,Q8N1F7,Q5JRA6,P50570,Q13277,Q8NHH9,P50402,Q9Y3B3,Q15629,Q9UQB8,Q96CP7,O75844,Q9BVK6,O14976,Q9P2W9,P83436,P20700,P41440 43 +Protein insertion into membrane 0.6620205675952601 3.0966288966439386 0.0019573474439449 0.9999964864800458 0.2687068745597027 30 Q9NPA0,O43681,P46379,Q9P0I2,Q9NS69,Q15629,O14737,P62072,Q9Y584,Q9P0J0,Q53H12,Q96A33,Q15070 13 +Cellular monovalent inorganic cation homeostasis 0.6816139934613212 3.085959125573348 0.0020289671162949 0.9999977819699862 0.2687068745597027 28 Q9Y6M7,P51790,P50897,Q93050,Q9HC07,P06576,O75503,P0CG08,Q96PU5,Q9Y487,Q8N511 11 +Protein transmembrane transport 0.683815491746649 3.0341354642664324 0.0024122608686827 0.9999998109533672 0.2687068745597027 27 O75298,Q99595,O60830,Q9UGP8,O75381,Q9NS69,P31751,O95831,Q15388,Q9Y584 10 +Mitochondrial transport 0.6097317715634808 3.0333936222681523 0.0024181995164784 0.9999998180312764 0.2687068745597027 89 P00846,Q99595,O60830,P45880,O95831,Q9Y584,Q9UJS0,Q9UJZ1,Q9NS69,O75964,O14737,Q15388,Q9UBX3,Q53H12,P62072,O43772,Q8N4H5,P51572,P55786,O75431,Q13794,P50416,Q10713,P23786,Q9P0J0,Q15070 26 +Organophosphate ester transport 0.6515967328893048 3.022727145566153 0.0025050800166064 0.9999998958787027 0.2687068745597027 30 Q86VD7,Q14108,P61916,Q8WTV0,Q4KMQ2,Q9H2D1,Q8TDW0,Q08722,P08183,O00400,Q8TB61,Q9BSK2,P33527,P41440 14 +Ph reduction 0.8252786108515001 2.9406799720086356 0.0032749269324736 0.9999999992617444 0.2687068745597027 13 P50897,Q93050,O75503,P0CG08,Q9Y487,Q8N511 6 +Protein targeting 0.5664211634134851 2.9289056183015663 0.0034015769200379 0.9999999996730704 0.2687068745597027 108 O43681,Q14108,P46379,Q99595,Q96RT1,O60830,P31751,O95831,Q9Y584,P27105,Q5BJH7,P49458,Q9UGP8,Q9NS69,O14737,O60725,Q15388,Q53H12,P62072,Q8N4H5,O75381,P51572,P55786,O00203,Q10713,P43307,Q9Y5M8,Q9P0J0 28 +Chemical homeostasis 0.4235785006237166 2.9268516256133736 0.003424121939987 0.9999999997172012 0.2687068745597027 183 P30519,P16615,O15254,P42785,Q9HCL2,P0CG08,Q5BJF2,P04114,Q9Y487,O75880,Q13586,P78417,Q8N511,P04899,P51790,P50897,Q8WTV0,Q93050,Q9NQC3,Q9UJZ1,P49366,O15118,P53985,Q96A33,P98194,P09601,Q9HD20,O75503,P51572,Q96PU5,O00203,Q9Y6C9,Q96CP7,Q9Y6M7,O95202,Q9HC07,P06576,O75787,O43819 39 +Regulation of ph 0.7006430818290532 2.917148842820396 0.0035324715947069 0.9999999998591366 0.2687068745597027 23 Q9Y6M7,P51790,P50897,Q93050,Q9HC07,P06576,O75503,P0CG08,Q9Y487,Q8N511 10 +Regulation of cellular ph 0.7006430818290532 2.917148842820396 0.0035324715947069 0.9999999998591366 0.2687068745597027 23 Q9Y6M7,P51790,P50897,Q93050,Q9HC07,P06576,O75503,P0CG08,Q9Y487,Q8N511 10 +Protein localization to endoplasmic reticulum 0.6136976799239248 2.884530389883416 0.0039199792212696 0.9999999999883584 0.2687068745597027 36 P49458,O43681,Q96HY6,P46379,P24390,Q9NQC3,Q9UGP8,Q9Y5M8,P51572,O43731,Q15629 11 +Protein targeting to mitochondrion 0.6121123852198137 2.8363883429233603 0.0045626929312461 0.999999999999814 0.2687068745597027 49 O43615,Q99595,O60830,O95831,Q9Y584,O14925,Q9NS69,O43464,O14737,Q15388,Q53H12,P62072,O95817,Q8N4H5,P51572,P55786,O95429,P60602,Q10713,Q9P0J0 20 +Inner mitochondrial membrane organization 0.6859571202552981 2.8246603977701263 0.004733075186637 0.999999999999938 0.2687068745597027 23 Q9Y584,Q9P0J0,Q53H12,Q5XKP0,O75431,P62072,Q13505 7 +Mitochondrial membrane organization 0.6095865294057103 2.8162625758276065 0.0048585939484222 0.9999999999999724 0.2687068745597027 49 O95202,Q9NS69,Q9P0J0,O14737,P45880,Q9Y584,Q13794,Q53H12,Q5XKP0,O75431,P62072,Q13505 12 +Establishment of protein localization to membrane 0.5853455928269847 2.7977083876251196 0.0051466555619914 0.9999999999999956 0.2687068745597027 88 O43681,P46379,Q9BRK0,Q9P0I2,P31751,Q8N2H4,Q9Y584,P27105,Q5BJH7,P49458,Q9UGP8,Q9NS69,O14737,O15118,O60725,Q96A33,Q53H12,P62072,P98194,Q13277,Q9HD20,O00203,P43307,Q9P0J0,Q15070 25 +Protein targeting to membrane 0.5928751156893969 2.739939226281608 0.00614505459183 1.0 0.279605924674817 33 P49458,P43307,O43681,P46379,Q9UGP8,P31751,O60725,P27105,Q5BJH7 9 +Mitochondrial respiratory chain complex assembly 0.5959743844971905 2.723364870257825 0.0064620645272446 1.0 0.279605924674817 42 O43676,O96000,Q9Y375,Q9H061,O95168,Q96CU9,Q9Y2R0,Q69YU5,O43819,O95831,Q9BSK2,P03886,O75880,Q9P0J0,Q6DKK2,Q8TB37,Q86Y39,Q15070 18 +Inorganic anion transport 0.6180203169285479 2.709988612651523 0.0067285518167115 1.0 0.279605924674817 29 O43681,P51790,P0CG08,P21796,P45880,P08183,Q9UHG3,Q9UBX3,Q9C0H2 9 +Neutral lipid biosynthetic process 0.9065469045229304 2.6935680949933833 0.0070691703538365 1.0 0.279605924674817 8 Q9HCL2,Q8WTV0 2 +Intracellular protein transmembrane transport 0.6638570164160417 2.6835550609432173 0.0072843979199317 1.0 0.279605924674817 23 O43615,O75298,Q99595,O60830,Q9UGP8,O75381,P31751,O95831,Q15388,Q15629,P60602 11 +Transition metal ion transport 0.7008181861009548 2.653713178511938 0.0079611465315454 1.0 0.279605924674817 16 O15173,P50570,P02786,P98194,Q9HC07,Q9HD20,P35670,Q8TAD4,Q15907,O75027 10 +Endoplasmic reticulum organization 0.5867407283407425 2.6382331338223213 0.0083339266041295 1.0 0.279605924674817 46 Q15363,O43681,Q9NPA0,Q00765,P46379,Q5JRA6,Q9BRK0,O14976,Q9NQC3,O95197,Q9P0I2,Q15629,Q9P2W9,Q96A33,Q12981 15 +Vacuolar acidification 0.8671767923860809 2.636022596411285 0.0083884145286439 1.0 0.279605924674817 9 Q93050,Q9Y487,P50897,Q8N511 4 +Establishment of protein localization to mitochondrial membrane 0.678896013713142 2.6164890146038227 0.0088839222958674 1.0 0.279605924674817 19 Q9NS69,O14737,Q9Y584,Q9P0J0,Q53H12,P62072,Q15070 7 +Triglyceride metabolic process 0.7573563742370405 2.5962427005401545 0.009424946561483 1.0 0.279605924674817 13 Q9UBV2,Q8WTV0,Q9HCL2,Q9BZK7,P04114,P50416 6 +Porphyrin containing compound metabolic process 0.6844033864140324 2.558393021794346 0.0105157169507941 1.0 0.279605924674817 16 P30519,Q9P0S9,P22830,P09601,P50336,P33527,Q7KZN9 7 +Vacuole organization 0.5771824296446117 2.5583432496687 0.0105172223227136 1.0 0.279605924674817 47 Q8TBX8,Q14108,P50897,P16615,Q8NHS3,Q9HC07,O75503,P54802,O00203,P11117,O14773,Q8N511 12 +Cytochrome complex assembly 0.7460778656653428 2.537602563598998 0.0111614657703886 1.0 0.279605924674817 13 Q9Y2R0,Q69YU5,O43819,Q9BSK2,Q6DKK2,Q7KZN9,Q15070 7 +Vitamin transport 0.7997823763038684 2.448313351874422 0.0143526771632802 1.0 0.3017351378519001 10 P38435,Q8WTV0,Q9H2D1,P33527,P41440 5 +Protein localization to mitochondrion 0.5641900895944059 2.4433640031817654 0.014551052640376 1.0 0.3017351378519001 62 O43615,Q99595,O60830,O95831,Q9Y584,O14925,Q9NS69,O43464,O14737,Q15388,Q53H12,P62072,O95817,Q8N4H5,Q07812,P51572,P55786,O00203,O95429,Q9P0J0,Q9Y6C9,P60602,Q10713,Q15070 24 +Entry into host 0.5621520847264077 2.4312735136860018 0.0150458517317457 1.0 0.3017351378519001 31 Q14108,O15118,Q8WTV0 3 +Triglyceride biosynthetic process 0.8833174317984628 2.426593909175187 0.0152413052337871 1.0 0.3017351378519001 7 Q9HCL2 1 +Cation transmembrane transport 0.4906937440371148 2.4263690697512637 0.0152507521553157 1.0 0.3017351378519001 122 P00846,P16615,Q96NB2,P00403,P21796,Q70HW3,O00400,P27105,Q13586,O75027,Q7KZN9,P78417,P51790,Q15758,Q9UJZ1,O75964,Q13423,P13073,O43772,Q9Y619,P50570,P98194,Q9HD20,Q96PU5,P20674,Q9UDW1,Q9Y6M7,P30825,O95202,Q9HC07,P06576 31 +Sphingolipid metabolic process 0.5770353761979918 2.4091345647852997 0.0159904009307105 1.0 0.3017351378519001 29 P50897,P16278,P06865,O95470,P07602,Q13510,O43464,P06280,Q8NCC3,Q9NZJ7,Q06136,Q53H12,O15269,Q96G23 14 +Protein transmembrane import into intracellular organelle 0.6994373929000841 2.3972037421983186 0.0165207346368401 1.0 0.3034324040749145 14 O43615,Q99595,O75381,O60830,O95831,Q15388,P60602 7 +Response to increased oxygen levels 0.8100667758134124 2.3825464434181396 0.01719336305029 1.0 0.311067467197227 9 Q9Y487,P00846 2 +Establishment of protein localization to organelle 0.3802823775078067 2.346110705643015 0.0189704719154777 1.0 0.32513562828399 169 O43681,Q14108,P46379,Q99595,O60830,O95831,Q9Y584,P49458,Q9UGP8,Q9NS69,O14737,Q15388,Q53H12,Q7Z4Q2,P62072,Q8N4H5,O75381,P51572,P55786,O00203,Q15629,Q9P0J0,Q9Y5M8,Q10713,Q15070 25 +Regulation of lysosomal lumen ph 0.8629563141301602 2.342246220985755 0.0191680647904732 1.0 0.32764612081849 7 Q9HC07,P50897,O75503,Q8N511 4 +Chloride transport 0.7067423855824277 2.3297515401425124 0.0198192867616548 1.0 0.3300473397900995 13 P08183,Q9UHG3,Q9C0H2 3 +Glycerophospholipid catabolic process 0.7709762910540296 2.313275238231558 0.0207075112092065 1.0 0.3377484652697557 10 Q8NCC3,Q8WTV0 2 +Cellular ion homeostasis 0.5294166127011954 2.3083778055253994 0.020978132336032 1.0 0.3404299449973813 92 P16615,P02786,P35670,P0CG08,O75880,Q9Y487,Q13586,O75027,P78417,Q8N511,P51790,P50897,Q93050,Q9UJZ1,Q14344,Q96A33,P23634,P98194,P09601,Q9HD20,O75503,P51572,Q96PU5,O00203,P20020,Q9Y6M7,O95202,Q9HC07,P06576,Q05086,O75787,O43819 32 +Vitamin transmembrane transport 0.8544332694648111 2.3066793120104876 0.0210727043987086 1.0 0.3411010989790974 7 P38435,P41440,Q8WTV0 3 +Nucleotide transport 0.6406964222843747 2.299149919974965 0.0214964276474658 1.0 0.3429326234298713 16 Q86VD7,Q9H2D1,Q08722,O00400,Q8TB61,Q9BSK2,Q8TDW0,P41440 8 +Phospholipid transport 0.6988334860219992 2.2873268456245297 0.0221767526759435 1.0 0.3478544446870812 13 Q14108,P61916,Q8WTV0,P08183,P33527 5 +Anion transport 0.5392357345214599 2.281413364416802 0.022523997952516 1.0 0.3483228548867455 78 Q14728,O43681,Q4KMQ2,Q96NB2,P07602,P0CG08,P21796,P45880,O00400,Q9NZJ7,P33527,Q9C0H2,O43808,O75915,Q9UJS0,Q86VD7,P51790,Q15758,Q9BQT8,Q08722,Q8TB61,Q9UBX3,P53985,Q9Y619,O95563,P08183,O75746,Q9Y277,Q9Y6M7,P30825,Q9H2D1,Q9UHG3,Q8TDW0,P14174,P41440 35 +Establishment of protein localization to endoplasmic reticulum 0.6124821294271302 2.269362465330826 0.0232462927713936 1.0 0.3542809844708827 21 P49458,O43681,P46379,Q9UGP8,Q9Y5M8 5 +Carbohydrate derivative transport 0.603677521600295 2.247733149611904 0.0245932108650932 1.0 0.3632315245282206 22 Q86VD7,P61916,Q8WTV0,P07602,Q08722,O00400,Q8TB61,Q9NZJ7,Q8TDW0,O43808,P41440 11 +Response to arsenic containing substance 0.7112563041904805 2.243241754598698 0.0248812290793261 1.0 0.3647094470550592 12 P09601,P78417 2 +Negative regulation of calcium ion transport 0.8007990680611801 2.2388599339649566 0.0251650311351834 1.0 0.3647094470550592 8 P21796 1 +Tetrapyrrole metabolic process 0.6174186241364895 2.2349808819254853 0.0254186038904518 1.0 0.3647094470550592 19 P30519,Q9P0S9,O14678,P22830,P09601,P50336,P33527,O75027,Q7KZN9 9 +Cellular response to arsenic containing substance 0.8371683155272104 2.2341611176939447 0.0254724737839124 1.0 0.3647094470550592 7 P78417 1 +Protein insertion into mitochondrial inner membrane 0.7987047073845452 2.229591898851336 0.0257745481626547 1.0 0.3671441193835937 8 Q9P0J0,P62072,Q9Y584 3 +Regulation of blood pressure 0.6247667441905291 2.2260745731536566 0.0260091867634557 1.0 0.36717516960252 17 Q9UIQ6,P42785,P09601,Q9HB40,P42892 5 +Proton transmembrane transport 0.5368361016393306 2.223565390267999 0.0261776992992748 1.0 0.36717516960252 47 P00846,P51790,P06576,Q9UJZ1,P00403,O75964,Q13423,Q9UDW1,P20674,Q7KZN9,P13073 11 +Sterol homeostasis 0.7069909835933575 2.221086470194603 0.0263451052450505 1.0 0.3687164293029996 12 P61916,Q8WTV0,Q6IAA8,O15118,Q5BJF2,P04114 6 +Phosphatidic acid metabolic process 0.7957047658996093 2.2162984810398716 0.026671066995678 1.0 0.3709847964934133 8 Q9NPH0 1 +Outer mitochondrial membrane organization 0.8962755056869702 2.2146711320126045 0.0267826457011819 1.0 0.3715947163302515 5 Q9NS69 1 +Cellular homeostasis 0.4104871281778749 2.2039345237462444 0.0275289491682597 1.0 0.3803029400184161 147 Q9NUT2,P16615,P02786,Q4KMQ2,P35670,P0CG08,O75880,Q9Y487,Q13586,O75027,P78417,Q8N511,Q8IYU8,Q9BXP2,P50897,P51790,Q93050,Q9NQC3,Q9UJZ1,Q14344,Q07820,Q8TAD4,Q96A33,Q15907,P23634,O95817,Q07812,P98194,P09601,Q9HD20,O75503,P51572,O95563,Q96PU5,O00203,P20020,Q16763,Q9Y3D6,Q9Y6M7,Q96RR1,O95202,Q9HC07,P06576,P10253,Q05086,O75787,O43819,P00390,Q9BWH2 49 +Macromolecule depalmitoylation 0.8924426625084776 2.199421100508843 0.0278479936378039 1.0 0.3822390561420205 5 Q9UMR5,P50897 2 +Mitochondrial atp synthesis coupled proton transport 0.7013128772531605 2.19150288589904 0.0284154211313008 1.0 0.383956942919691 12 O75964,P00846,Q9UJZ1 3 +Glycoside catabolic process 0.8889313185818657 2.1854277326910267 0.0288574993169368 1.0 0.3860852285146051 5 Q9NUJ1,P06280 2 +Iron ion homeostasis 0.6131893448396066 2.179814004822801 0.0292712513925079 1.0 0.3868251540558588 18 Q9Y487,P30519,Q8N511 3 +Calcium ion regulated exocytosis 0.7640731792726309 2.172494481398731 0.0298183854446867 1.0 0.3892058714587879 9 P16615,Q9BRK5 2 +Atp synthesis coupled proton transport 0.6765611934678708 2.166703591458288 0.0302574625778311 1.0 0.3910711472781764 13 O75964,P00846,Q9UJZ1 3 +Negative regulation of calcium ion transmembrane transport 0.8424767018842696 2.166660749672634 0.030260731521057 1.0 0.3910711472781764 6 P21796 1 +Calcium ion import 0.6568940287268629 2.1597352155298313 0.0307931733792643 1.0 0.3943004074350952 14 O75844,P21796 2 +Ion homeostasis 0.4948136485940708 2.159412546706533 0.0308181753705121 1.0 0.3943004074350952 107 P30519,P16615,P02786,P35670,P0CG08,O75880,Q9Y487,Q13586,O75027,P78417,Q8N511,P04899,Q9BXP2,P50897,P51790,Q93050,Q9UJZ1,Q14344,Q96A33,P23634,P98194,P09601,Q9HD20,O75503,P51572,Q96PU5,O00203,P20020,Q9Y6M7,O95202,Q9HC07,P06576,Q05086,O75787,O43819 35 +Mitochondrial electron transport cytochrome c to oxygen 0.8399610279840855 2.156223521196167 0.0310662157440118 1.0 0.3958935246900908 6 P20674,Q7KZN9,P13073 3 +Lysosomal lumen acidification 0.881110309215795 2.1541823467426866 0.0312258747088221 1.0 0.3964230159439854 5 P50897,Q8N511 2 +Membrane lipid metabolic process 0.5247084150944181 2.152985810840477 0.0313197936972156 1.0 0.3964230159439854 40 P50897,P16278,Q92643,P06865,Q8NBX0,O95470,P07602,Q13510,O43464,P06280,Q8NCC3,O60762,Q9NZJ7,Q06136,Q53H12,O15269,Q96G23 17 +Amino acid transmembrane transport 0.6320584248892668 2.1264401491580123 0.0334666277447699 1.0 0.3997776619326592 15 Q9Y619,P30825,Q96NB2,Q15758,O60831,O75746,Q8TDW0,O75915,Q9UJS0 9 +Protein insertion into er membrane 0.686265207723635 2.1126060405842884 0.0346345012750803 1.0 0.4103644236104718 12 O43681,P46379,Q9P0I2,Q96A33,Q15629 5 +Adult locomotory behavior 0.6477477198203808 2.1078160459155666 0.0350469043475327 1.0 0.4106747449218094 14 O75844,O15118,P50897 3 +Pattern recognition receptor signaling pathway 0.5652437418278587 2.107159501040506 0.0351037561200127 1.0 0.4106747449218094 25 Q9NPR9,Q96RT1,Q9NQC3,Q5KU26,O00203,O43657,P41440 7 +Fatty acid transmembrane transport 0.7711731793609041 2.1067990102253673 0.0351350053380301 1.0 0.4106747449218094 8 O43772,P23786,P50416,P31751 4 +Nadh dehydrogenase complex assembly 0.5203688747108937 2.100124883204826 0.0357178569412002 1.0 0.4120489774912423 31 O43676,O96000,Q9H061,O95168,Q96CU9,P03886,Q9Y375,Q9P0J0,Q8TB37,Q86Y39,Q15070 11 +Immune response regulating signaling pathway 0.5207262634523296 2.0905387703697653 0.036569429446958 1.0 0.4185893620625021 46 Q9NPR9,P46379,Q96RT1,Q9NQC3,O75955,Q9UJZ1,Q08722,O00203,Q5KU26,Q9NR50,O43657,P41440 12 +Mannosylation 0.7671845554827023 2.088861674956983 0.0367201766356697 1.0 0.4188457562143123 8 Q9BV10,Q9BT22,Q6ZXV5,O60762,O43505 5 +Regulation of pattern recognition receptor signaling pathway 0.6047474050942513 2.079880425695451 0.0375365018464668 1.0 0.4228741072990133 16 Q9NPR9,Q96RT1,Q9NQC3,O43657,P41440 5 +Protein import into mitochondrial matrix 0.701823604347609 2.0796849523804006 0.0375544391853264 1.0 0.4228741072990133 11 O43615,Q99595,O60830,Q15388,P60602 5 +L alpha amino acid transmembrane transport 0.7012812190745655 2.076938908888103 0.0378071980359042 1.0 0.4234867946351447 11 Q9Y619,P30825,Q15758,O60831,O75746,O75915,Q9UJS0 7 +Neurotransmitter secretion 0.5997302619236518 2.070430582747427 0.0384120403827057 1.0 0.4282107458315543 17 Q13277,P16615,P50897 3 +Protein quality control for misfolded or incompletely synthesized proteins 0.6770007623732939 2.063672930923952 0.0390487375494013 1.0 0.4324007059880733 12 Q96TA2,Q16740,P46379 3 +Organic acid transport 0.5185827953397457 2.057875343970391 0.0396021011212803 1.0 0.4324007059880733 50 O14678,Q96NB2,P31751,P33527,O75915,Q9UJS0,Q15758,Q9BQT8,Q9UBX3,P53985,Q96H78,O43772,Q9Y619,O95563,P08183,O75746,P50416,P30825,Q6P4A7,Q9H2D1,P23786,Q8TDW0,P14174,P41440 24 +Negative regulation of transmembrane transport 0.5938238707423736 2.0572228438348152 0.0396647951316564 1.0 0.4324007059880733 18 P21796,Q96PU5,P31751,P78417 4 +Nerve development 0.8161417557488011 2.0567847688335874 0.0397069338281421 1.0 0.4324007059880733 6 Q9H061 1 +Amino acid transport 0.5844220891254842 2.0521628719443155 0.0401538364205313 1.0 0.4324007059880733 20 Q9Y619,P30825,Q6P4A7,Q96NB2,Q15758,O60831,Q8TDW0,O75746,Q96H78,O75915,Q9UJS0 11 +Cellular response to increased oxygen levels 0.8144524322110513 2.049690229672719 0.0403946690501189 1.0 0.4324007059880733 6 Q9Y487 1 +Lysosomal protein catabolic process 0.7375372872522743 2.048875147903358 0.0404743250534858 1.0 0.4324007059880733 9 Q8NHS3,Q8N511 2 +Protein catabolic process in the vacuole 0.7375372872522743 2.048875147903358 0.0404743250534858 1.0 0.4324007059880733 9 Q8NHS3,Q8N511 2 +Phosphatidylcholine catabolic process 0.9208143554082906 2.0303187405404466 0.0423241504898401 1.0 0.4368724712397351 4 Q8WTV0 1 +Regulated exocytosis 0.503346275075402 2.0293448045727223 0.0424231827659349 1.0 0.4371906777003905 32 P16615,Q13277,P09601,Q9BRK5,O43760 5 +Homologous chromosome pairing at meiosis 0.7332127599360463 2.02856091540173 0.0425030328973117 1.0 0.4373104989916022 9 Q92791,P46379,Q9BTX1,Q9BXW9 4 +Endoplasmic reticulum membrane organization 0.711044461382042 2.0250990243332936 0.0428571970827669 1.0 0.4395434132808575 10 Q15363,Q00765,Q9NQC3,Q9P2W9,Q12981 5 +Nucleotide transmembrane transport 0.6899971843779679 2.019613650950546 0.0434234780631936 1.0 0.4446397673882932 11 Q86VD7,Q9H2D1,Q8TB61,Q9BSK2,Q8TDW0,P41440 6 +L amino acid transport 0.6680591121169932 2.016186485609739 0.0437804790604381 1.0 0.4468676286264466 12 Q9Y619,P30825,Q15758,O60831,O75746,O75915,Q9UJS0 7 +Calcium mediated signaling 0.59372768017873 2.0115677431978365 0.0442655225660972 1.0 0.4495976060492902 16 O75844,P16615,P51572,P78417,P23634 5 +Negative regulation of ion transmembrane transport 0.6302933811016909 2.007886046199681 0.0446554023065579 1.0 0.4507734311575377 14 P21796,Q96PU5,P78417 3 +Inorganic ion transmembrane transport 0.4610271631880056 1.986698352507871 0.0469558345097125 1.0 0.4659239925808936 118 P00846,Q9NUT2,P16615,Q9H936,Q4KMQ2,P00403,P35670,P21796,Q6P4Q7,O00400,P27105,Q13586,O75027,Q7KZN9,P78417,Q8IYU8,Q9BXP2,P51790,Q9UJZ1,P24539,O75964,Q9UBX3,Q8TAD4,P23634,Q13423,P13073,Q04656,Q07812,P25705,P50570,P98194,Q9HD20,Q96PU5,P20020,P20674,Q9UDW1,Q9Y6M7,O95202,Q9HC07,P06576,Q9UHG3 41 +Pigment metabolic process 0.5346431105454209 1.9784417800085037 0.0478788903823867 1.0 0.4714342355623646 27 P30519,Q9P0S9,P22830,Q06203,P09601,P50336,P33527,O75027,Q7KZN9,O00264 10 +Sarcoplasmic reticulum calcium ion transport 0.7955734866938216 1.9700301229658332 0.0488349183427263 1.0 0.4742906463285998 6 O75844,P78417 2 +Chemokine production 0.7395360996354854 1.963501587726328 0.0495879201746936 1.0 0.4774121463849373 8 P14174,P09601 2 +Cell recognition 0.5790732765209008 1.962728963843724 0.049677675762676 1.0 0.4774121463849373 18 P45880,Q8WTV0 2 +Toll like receptor signaling pathway 0.6344842514345185 1.9341856859272184 0.0530903016764559 1.0 0.4965592329345172 13 Q9NPR9,Q9NQC3,O00203,Q5KU26,P41440 5 +Regulation of calcium ion dependent exocytosis 0.825318768480449 1.928251203773707 0.053823888061891 1.0 0.5014696547626771 5 P16615 1 +Import across plasma membrane 0.5654673342369687 1.926647088066442 0.054023626111461 1.0 0.5018716570644426 20 Q9BXP2,P30825,Q15758,P31751,Q8TDW0,O75915,P41440 7 +Smad protein signal transduction 0.7308780879118343 1.923881451781595 0.054369444678227 1.0 0.5036244803286636 8 Q6PIU2,P08670,Q9UIQ6,O00400 4 +Cellular response to oxygen levels 0.4938685874326108 1.919089124522 0.0549730555857987 1.0 0.5084809326190047 36 Q96A26,P09601,P55786,O95831,Q9Y487,Q13794,Q8N511 7 +Regulation of response to osmotic stress 0.7818088719185299 1.911520350564081 0.0559377441042574 1.0 0.5124635367218217 6 O95202,P08183 2 +Sensory perception of light stimulus 0.6133005828969551 1.9095345172588472 0.0561931733511469 1.0 0.5124635367218217 14 Q9H6K4,P50897 2 +Adult behavior 0.5627205345348123 1.9083203256050063 0.0563498275292311 1.0 0.5124635367218217 20 O75844,O15118,P50897 3 +Negative regulation of proteasomal protein catabolic process 0.5575134444163851 1.903291078222343 0.0570025743654694 1.0 0.5124635367218217 21 Q8N163,Q96HY6,P46379,Q9UL15,Q9GZU8,Q92530 6 +Xenobiotic transport 0.817628874875843 1.8967029703365976 0.0578671514679713 1.0 0.518781036237338 5 P33527,P08183,P41440 3 +Plasma membrane organization 0.555760751483989 1.8913812334699176 0.0585734718732848 1.0 0.5236484723957546 21 P16615,P50570,O75955,Q9Y5X1,P31751,Q9UQB8,P41440,Q96CP7 8 +Homologous chromosome segregation 0.6648423949291931 1.8904905660444988 0.0586923811167134 1.0 0.5239377065233232 11 Q92791,P46379,Q9BTX1,Q9BXW9 4 +Lipoprotein localization 0.7766044022020779 1.88930451257964 0.0588510372381891 1.0 0.5239377065233232 6 Q13432,A6NIH7,P04114 3 +Posttranslational protein targeting to endoplasmic reticulum membrane 0.7562857339060374 1.886057024693369 0.0592872706507341 1.0 0.5242455382601917 7 O43681,P46379 2 +Excretion 0.8827838531455398 1.8837704434381377 0.0595960331561489 1.0 0.5242455382601917 4 P04899,P09601 2 +Endoplasmic reticulum to golgi vesicle mediated transport 0.5007544078509115 1.8816030724929944 0.0598899287546348 1.0 0.5245731953322954 66 Q15363,Q5JRA6,P24390,O95249,O95070,Q6NUQ1,Q96RQ1,Q8NHH9,Q9P2W9,P51572,Q96PC5,Q9Y3B3,Q9BSR8,Q9Y282,O43731,O14653,Q5BJH7,Q8WU17 18 +Mitochondrial calcium ion transmembrane transport 0.6818735545657506 1.8813104440259385 0.0599297011331292 1.0 0.5245731953322954 10 P21796,O95202 2 +Transition metal ion homeostasis 0.5201338739448406 1.8689864402505685 0.0616247009241801 1.0 0.5325903716702299 27 P30519,P02786,P09601,O43819,O00203,O75880,Q9Y487,O75027,Q8N511 9 +Ceramide metabolic process 0.56404204591564 1.8654551295702744 0.0621176360565622 1.0 0.5351801708636617 18 P06865,O95470,Q13510,P06280,Q8NCC3,Q53H12,Q96G23 7 +Regulation of small gtpase mediated signal transduction 0.4833789160196467 1.861908282537409 0.062616019387178 1.0 0.5380277269059136 32 P50570,Q96RT1,O75955,O15294,Q5VZ89,Q4VCS5,O94813,Q9NUQ9,Q96AG4,P41440 10 +Cotranslational protein targeting to membrane 0.6046811075942538 1.859250240280768 0.0629916765457456 1.0 0.5390876457386244 14 P49458,Q9UGP8,P43307 3 +Respiratory chain complex iii assembly 0.8074814535543879 1.854927209855599 0.0636066217778954 1.0 0.5436037968724826 5 Q9BSK2,Q69YU5 2 +Metal ion export 0.6758893791032785 1.851533699553956 0.0640928112499876 1.0 0.5444171600099726 10 Q04656,O95202,Q4KMQ2,P35670,P20020,P23634 6 +Tail anchored membrane protein insertion into er membrane 0.6958212108519055 1.8509770428182872 0.0641728558700915 1.0 0.5444171600099726 9 Q9P0I2,O43681,P46379 3 +Dicarboxylic acid transport 0.5617519203240839 1.8505487554262297 0.0642344977469391 1.0 0.5444171600099726 18 Q9H2D1,Q15758,O60831,Q9BQT8,O75746,Q9UBX3,Q8TDW0,O75915,P41440,Q9UJS0 10 +Export across plasma membrane 0.6945354651788453 1.8448096848702629 0.0650652281039025 1.0 0.5444171600099726 9 P33527,Q4KMQ2,P20020,P08183 4 +Tetrapyrrole catabolic process 0.8726183609046263 1.8442740746783788 0.0651432077578235 1.0 0.5444171600099726 4 P30519 1 +Organic cation transport 0.745807842804587 1.839971312787788 0.0657724491031053 1.0 0.5458556406685543 7 O43772,Q70HW3 2 +Response to food 0.8033474529402148 1.8378613251654925 0.0660828422889636 1.0 0.5458556406685543 5 Q9UMX5,P80303 2 +Protein deglycosylation 0.7115548107759416 1.8348403732524536 0.0665293446072319 1.0 0.5458556406685543 8 O60476,O60502 2 +Sulfur compound transport 0.6337018974834948 1.8313928762987792 0.0670419238208597 1.0 0.5458556406685543 12 Q70HW3,O00400,Q8TB61,Q9UBX3,P33527 5 +Sensory perception 0.4875023495262813 1.8313902264144808 0.0670423190565998 1.0 0.5458556406685543 31 Q14108,P50897,Q13432,Q9H6K4,P62072 5 +Intracellular lipid transport 0.5828574546651893 1.831331682351626 0.0670510515143283 1.0 0.5458556406685543 15 O43772,P61916,P23786,O15118,P50416,Q9P260 6 +Sodium ion transmembrane transport 0.5511003488867465 1.830409131795715 0.0671887832273774 1.0 0.5458556406685543 20 Q9Y6M7,P50570,Q4KMQ2,Q96PU5,Q12955,Q6P4Q7,P27105,P23634 8 +Mitochondrial protein processing 0.7617963649453353 1.825820439937339 0.067877313393301 1.0 0.5475823521672549 6 Q10713,Q96TA2 2 +Cellular iron ion homeostasis 0.5808176973159108 1.8188960721342036 0.0689272872163695 1.0 0.5519491453968818 15 Q9Y487,Q8N511 2 +Oxidative phosphorylation 0.4932961127719607 1.8180386621180271 0.0690582238078469 1.0 0.5519491453968818 70 O43676,P00846,O95182,P22695,O96000,O14949,P14406,O95168,Q9UJZ1,P00403,O75964,P14635,P03886,Q9BSK2,P20674,Q9UDW1,Q7KZN9,P13073 18 +Metal ion homeostasis 0.4876632571004778 1.816362547847397 0.0693147763167558 1.0 0.5528183491363202 83 P30519,P16615,P02786,P35670,Q6P4Q7,O75880,Q9Y487,Q13586,O75027,P78417,Q8N511,Q8IYU8,P04899,Q9BXP2,Q9UJZ1,Q14344,Q8TAD4,Q96A33,P23634,Q04656,Q07812,P98194,P09601,Q9HD20,P51572,Q12955,Q96PU5,O00203,P20020,Q9Y3D6,P05023,O95202,Q9HC07,Q8NE01,O43819 35 +Peptide catabolic process 0.6682675730309662 1.813472827462503 0.0697589258813082 1.0 0.553691868023618 10 P55786,Q9UIQ6,P42892,Q9NZ08 4 +Regulation of response to extracellular stimulus 0.7970926707341478 1.811989936438464 0.0699877514904334 1.0 0.5545383029093677 5 P80303 1 +Respiratory chain complex iv assembly 0.7056707217942098 1.807560419965726 0.0706749430706941 1.0 0.5575743914050599 8 O43819,Q9Y2R0,Q7KZN9,Q15070 4 +Lipid homeostasis 0.4918582353819022 1.8066501329772624 0.0708168475154997 1.0 0.5575743914050599 30 Q8WTV0,Q9HCL2,O15118,Q5BJF2,Q96CP7 5 +Carboxylic acid transport 0.4803710979885806 1.8040500904092451 0.0712234548204768 1.0 0.5575743914050599 36 Q9Y619,P30825,Q96NB2,Q15758,Q9H2D1,P07602,Q9BQT8,O95563,Q8TDW0,Q9UBX3,P53985,O75746,P33527,P14174,O75915,P41440,Q9UJS0 17 +Maintenance of protein localization in endoplasmic reticulum 0.8622340487878835 1.8037931730881265 0.0712637364834463 1.0 0.5575743914050599 4 P24390 1 +Protein retention in er lumen 0.8622340487878835 1.8037931730881265 0.0712637364834463 1.0 0.5575743914050599 4 P24390 1 +Terpenoid metabolic process 0.5501877489969991 1.7981501437783638 0.072153217778961 1.0 0.5575743914050599 19 P41247,P48449,P37268,O43464,Q9BTZ2,P51648,Q6NUM9,Q9HB40,Q9HBH5,P14324 10 +Positive regulation of chemokine production 0.7541429173800756 1.7928526075927906 0.0729964950159995 1.0 0.5576967020888646 6 P09601 1 +Regulation of cardiac muscle contraction by calcium ion signaling 0.7916221126048636 1.7893131023033169 0.0735644051269956 1.0 0.5589758167217718 5 P78417 1 +Walking behavior 0.8565115995439933 1.7814290696086412 0.0748423828080768 1.0 0.5643996162350268 4 O15118 1 +Negative regulation of proteasomal ubiquitin dependent protein catabolic process 0.5528553346068745 1.7717694599541436 0.0764328340816378 1.0 0.5694195986784314 17 Q8N163,Q9UL15,Q96HY6,P46379 4 +Negative regulation of leukocyte migration 0.7866750798284168 1.76876751288681 0.0769326803416434 1.0 0.5694195986784314 5 P14174,P09601,O94813 3 +Amyloid precursor protein metabolic process 0.5491039974160588 1.7678212694867577 0.0770907879757523 1.0 0.5694195986784314 18 Q9NQX7,O75298,Q9NQC3,Q15392,O95197,Q96IZ0 6 +Neuron apoptotic process 0.4814866977538781 1.7665600658041505 0.0773019338428189 1.0 0.5694195986784314 43 Q99720,P50897,Q96A26,P09601,P31751 5 +Diacylglycerol biosynthetic process 0.9841731266149858 1.765518843537614 0.0774766061387404 1.0 0.5694195986784314 2 Q9HCL2 1 +Atp biosynthetic process 0.5329699409821923 1.765018072602028 0.0775607283878225 1.0 0.5694195986784314 22 P00846,Q9UJZ1,P00403,O75964,O75746,Q9UJS0 6 +Xenobiotic metabolic process 0.6043708653753084 1.7641222296007804 0.0777114026021128 1.0 0.5694195986784314 13 Q6PIU2,O43169,P07099,P78417 4 +Reactive nitrogen species metabolic process 0.5718561854803801 1.7640771100542856 0.0777189976799239 1.0 0.5694195986784314 15 P16435,P50570,P06280,Q08722,O43169,P23634 6 +Diacylglycerol metabolic process 0.851702853797615 1.7626056052420604 0.0779670310524687 1.0 0.5694195986784314 4 Q9HCL2 1 +Vascular process in circulatory system 0.493060878531648 1.7603368158797374 0.0783507154499807 1.0 0.5694195986784314 29 P30825,P02786,Q15758,Q16625,O94813,P08183,P20020,P53985,P33527,Q9HB40,P42892,P41440 12 +Phosphatidylcholine metabolic process 0.5525175969384374 1.7516148494957198 0.0798400574385169 1.0 0.5756746548716465 16 Q8NCC3,Q8IY17,Q8WTV0 3 +Regulation of embryonic development 0.5486982670284491 1.744838818461185 0.0810129296089792 1.0 0.5821669044770815 17 P46379 1 +Positive regulation of release of cytochrome c from mitochondria 0.723939713790722 1.7430873357474037 0.0813183604197622 1.0 0.5837073799447661 7 Q96A26,O14737 2 +Amino acid import 0.6916638508579677 1.7423161892870145 0.0814531321282017 1.0 0.5840046541746832 8 Q96NB2,O75915,P30825 3 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.5148405971465905 1.7412880497484131 0.0816330998659151 1.0 0.5840046541746832 25 P24390,Q6NUQ1,Q96RQ1,Q9P2W9,P83436,O43731,Q12981,Q9Y282 8 +T cell apoptotic process 0.6360937948621117 1.7407197996084127 0.0817327059303776 1.0 0.5840653790565447 11 Q9HCL2 1 +Negative regulation of lymphocyte apoptotic process 0.7791974476725042 1.7376432459638338 0.0822736947238675 1.0 0.5853519925735204 5 Q9HCL2 1 +Negative regulation of leukocyte apoptotic process 0.7791974476725042 1.7376432459638338 0.0822736947238675 1.0 0.5853519925735204 5 Q9HCL2 1 +Negative regulation of cell projection organization 0.4833856132782558 1.73761868187478 0.0822780257891953 1.0 0.5853519925735204 30 Q9NQX7,P50570,O14976,Q9NQC3,Q9UL15,Q05086,O94813,Q9NR77,P08670,Q15375,Q96G23 11 +Response to retinoic acid 0.6160591314057929 1.7350957236012925 0.082723851647732 1.0 0.5872202536677321 12 P02786,Q8TB36,O43464,Q13573,Q99623,Q9NVR5,Q9P0J0 7 +Glial cell development 0.583322212926462 1.733524223172721 0.0830025359034472 1.0 0.5881669210873265 14 Q9NR50,P08670,P31751,O43175 4 +Protein depalmitoylation 0.8439465360241596 1.7321872978068082 0.0832402198906847 1.0 0.5882798340675736 4 P50897 1 +Lipoprotein catabolic process 0.7399215155464824 1.731317295929897 0.0833951882667254 1.0 0.5887259436010022 6 P50897,Q9NUJ1 2 +Nuclear pore organization 0.615252773522208 1.7306724349589235 0.0835102043317568 1.0 0.588889339677185 12 Q8N1F7,Q96EE3,Q9BTX1,Q9NQC3,P57740,Q7Z3B4,Q8NFH5 7 +Negative regulation of macroautophagy 0.6328901374315926 1.7238889355893354 0.0847278951186452 1.0 0.5922636943408024 11 Q9NQ88,P09601,Q9NRR5,O15118 4 +Organic anion transport 0.4821306812024307 1.7208006262809867 0.0852870087493027 1.0 0.595522577432495 55 Q96NB2,P07602,O00400,Q9NZJ7,P33527,O75915,Q9UJS0,Q86VD7,Q15758,Q08722,Q9BQT8,Q8TB61,Q9UBX3,P53985,Q9Y619,O95563,O75746,Q9Y6M7,P41440,P30825,Q9H2D1,Q8TDW0,P14174,Q14728 24 +Cellular response to gamma radiation 0.686084393720611 1.7162094495080749 0.0861237143089219 1.0 0.5956677937022973 8 P12956 1 +Negative regulation of response to food 0.9715762273901812 1.7155317927336318 0.0862477716166227 1.0 0.5956677937022973 2 P80303 1 +Regulation of response to food 0.9715762273901812 1.7155317927336318 0.0862477716166227 1.0 0.5956677937022973 2 P80303 1 +Regulation of appetite 0.9715762273901812 1.7155317927336318 0.0862477716166227 1.0 0.5956677937022973 2 P80303 1 +Sphingoid metabolic process 0.7737460454209363 1.7149016589538844 0.0863632584604048 1.0 0.5956677937022973 5 Q13510,Q06136 2 +Connective tissue development 0.5256582213821764 1.7137285896211216 0.0865785836811756 1.0 0.5956677937022973 22 O75844,P16435,O15173,P43490,Q92896,Q9BZK7 6 +Response to l glutamate 0.7732892707195247 1.712994209081068 0.086713604960368 1.0 0.5956677937022973 5 Q9UQB8 1 +Negative regulation of neuron projection development 0.5254505841701508 1.7122684979432223 0.0868471992699375 1.0 0.5956677937022973 22 Q9NQX7,O14976,Q9NQC3,Q9UL15,Q9NR77,P08670,Q15375,Q96G23 8 +Torc1 signaling 0.7354848700157661 1.7120485356663346 0.0868877243612507 1.0 0.5956677937022973 6 Q8NHS3 1 +Iron ion transport 0.6480602836677428 1.7118445165562357 0.0869253257830309 1.0 0.5956677937022973 10 Q04656,O15173,P50570,P02786,Q15907,O75027 6 +Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.7350916423105343 1.7103390994492047 0.0872031855435944 1.0 0.5956677937022973 6 Q8N163,Q96K76 2 +Endoplasmic reticulum tubular network organization 0.5947776611346013 1.7093282329772248 0.0873901664078249 1.0 0.5956677937022973 13 Q6NUK4,Q9BRK0,Q9NQC3,Q8NHH9,O95197 5 +Modified amino acid transport 0.7345835812243463 1.7081300740750054 0.0876122097308498 1.0 0.5956677937022973 6 O43772,Q9H2D1,P41440 3 +Phospholipid homeostasis 0.9696382428940538 1.7078338170419596 0.0876671823332859 1.0 0.5956677937022973 2 Q9HCL2 1 +Regulation of mitophagy 0.7337933198335465 1.7046931909877172 0.0882516604259107 1.0 0.5973528440655624 6 P21796 1 +Regulation of membrane lipid distribution 0.7711009534986331 1.703851909177239 0.0884087573451104 1.0 0.5977849520908839 5 P33527,P08183,Q96CP7 3 +Skeletal system morphogenesis 0.543961439542004 1.6967823141688294 0.0897378236116956 1.0 0.6030610825726634 16 O75844,P16435,Q92896 3 +Response to oxygen levels 0.4806787702784629 1.6962019886683268 0.0898476339870348 1.0 0.6030610825726634 61 P00846,P30519,Q96A26,P09601,P55786,O95831,Q9Y487,Q8N511 8 +Aminoglycan metabolic process 0.5604816314051422 1.6940728528174451 0.0902514401774654 1.0 0.6033662736377755 15 P16278,P06865,P54802,P15586,Q8NCH0,O43505,O94923 7 +Sphingolipid biosynthetic process 0.5599619804159802 1.690863557724513 0.0908628648295426 1.0 0.6041499159660888 15 O95470,Q13510,Q53H12,Q06136,Q96G23 5 +Cellular hormone metabolic process 0.5291658234343356 1.681702005998241 0.0926266388644216 1.0 0.6041536042859702 20 Q53GQ0,P41247,O95470,Q9HBH5,Q6UX07,Q9BTZ2,Q6NUM9,Q9HB40,P42892,Q15648,Q8NBN7 11 +Cellular transition metal ion homeostasis 0.5163366715960996 1.6793765884015737 0.0930786730492052 1.0 0.6041536042859702 23 P02786,P09601,O43819,O00203,O75880,Q9Y487,O75027,Q8N511 8 +Antigen processing and presentation of peptide antigen 0.6047586392759082 1.672935204387228 0.0943400524784032 1.0 0.6078431277015908 12 Q03518,Q9UIQ6,Q9NZ08,P10321 4 +Fibroblast proliferation 0.5559860263151059 1.666276972153113 0.0956582611175056 1.0 0.6078431277015908 15 O75844,P50402,P14635,Q71SY5,P14174,Q96IZ0 6 +Positive regulation of macroautophagy 0.5381877219847973 1.6596214658362778 0.0969906272156468 1.0 0.6078431277015908 16 Q8TBX8,P21796,P09601 3 +Positive regulation of toll like receptor signaling pathway 0.7605193161619804 1.659550617946112 0.0970048896757707 1.0 0.6078431277015908 5 Q9NQC3,P41440 2 +Toll like receptor 3 signaling pathway 0.8254562583048755 1.6594032865190111 0.0970345544837447 1.0 0.6078431277015908 4 Q5KU26,P41440 2 +Antigen processing and presentation of exogenous peptide antigen 0.7604029542484838 1.659062609476889 0.0971031767186316 1.0 0.6078431277015908 5 Q03518,Q9UIQ6,P50570 3 +Protein localization to membrane raft 0.7595615299248659 1.6555332354940366 0.0978163804687894 1.0 0.6099250961137554 5 Q9BRK0,P41440 2 +Purine nucleotide transport 0.584318418737896 1.6492614739446814 0.099094078746345 1.0 0.6120486478066423 13 Q86VD7,Q08722,O00400,Q8TB61,Q8TDW0,P41440 6 +Positive regulation of transmembrane transport 0.4789000009018817 1.6467108468045544 0.0996174936504792 1.0 0.6133987841494446 29 P50570,Q4KMQ2,Q16625,P31751,P08183,Q13586,P78417 7 +Isoprenoid metabolic process 0.5113969135427585 1.6438863373374506 0.1001996828469709 1.0 0.6152106964071681 23 P41247,P61916,P48449,P37268,O43464,Q9BTZ2,O60762,P51648,Q6NUM9,Q9HB40,Q9HBH5,P14324 12 +Hormone metabolic process 0.4718166044621766 1.642660915853637 0.100453109585159 1.0 0.616176490374038 30 O75844,Q53GQ0,P16435,P41247,P05023,O95470,O75787,Q9HBH5,Q6UX07,Q9BTZ2,Q8TAD4,Q6NUM9,Q9HB40,P42892,Q15648,Q8NBN7 16 +Neurotransmitter transport 0.5108513539003484 1.6399599010880663 0.1010135046759681 1.0 0.6184303390381622 23 P16615,P50897,Q13277,O75955,P41440 5 +Bone morphogenesis 0.7170922555716427 1.631818659769487 0.1027176932228384 1.0 0.6205734596262361 6 O75844,Q92896 2 +Regulation of calcium ion transmembrane transport 0.5281473748621248 1.6292916899479233 0.1032512845091524 1.0 0.6205734596262361 18 P21796 1 +Cdp diacylglycerol metabolic process 0.6983329308006918 1.6284887661517404 0.1034212893334367 1.0 0.6205734596262361 7 Q99943,Q9HCL2 2 +Protein trimerization 0.8173285013251318 1.6272964981953697 0.1036741412866075 1.0 0.6205734596262361 4 P14174,Q99720 2 +Negative regulation of ion transport 0.5306198593397212 1.626922934872873 0.1037534662733596 1.0 0.6205734596262361 17 P21796,Q96PU5,P78417 3 +Positive regulation of cysteine type endopeptidase activity 0.4764188929845944 1.626685822732938 0.1038038413026281 1.0 0.6205734596262361 29 Q07812,Q9Y3D6,Q96F07,Q96A26,O43464,P51572,O14737,O95831,Q9NZJ7,Q9P0J0,O75915,Q13794 12 +Regulation of necrotic cell death 0.630817103600717 1.6243263810734394 0.1043061697933613 1.0 0.6205734596262361 10 Q13510,P00403,P16989 3 +Protein localization to golgi apparatus 0.6490416395890615 1.624099763024112 0.1043545185544321 1.0 0.6205734596262361 9 O14976,Q92538,Q96RL7,P83436,Q8N2H4,P40616 6 +Cartilage development 0.6133460304522633 1.6206252711587044 0.1050980290791061 1.0 0.6231992288594546 11 O75844,P16435,Q92896 3 +Membrane protein proteolysis 0.6482170277805399 1.6200563374941217 0.105220175482497 1.0 0.6233411247658972 9 Q16740,Q9NZ08,Q9Y5X1 3 +Regulation of er to golgi vesicle mediated transport 0.6963595688671648 1.619608283822309 0.105316449004909 1.0 0.6233411247658972 7 Q9P2W9,Q8WU17 2 +Lymphocyte apoptotic process 0.5292173817064235 1.6177224898249465 0.1057224169892199 1.0 0.6240370270135521 17 P24390,Q9HCL2 2 +Ribonucleoprotein complex localization 0.6930816386536334 1.6048420832142278 0.1085285620230587 1.0 0.6352962734763076 7 Q08J23 1 +Regulation of toll like receptor signaling pathway 0.6448647078900082 1.6036035956642014 0.1088014576723399 1.0 0.6352962734763076 9 Q9NPR9,Q9NQC3,P41440 3 +Biomineralization 0.6086866581985036 1.5958627630370903 0.1105194367992743 1.0 0.6411127510256548 11 O75844,Q9UNW1,Q4KMQ2,P20020,Q13586 5 +Regulation of triglyceride metabolic process 0.8083354243385465 1.5916967854703166 0.1114528509685166 1.0 0.6441954686277652 4 Q9BZK7,Q8WTV0 2 +Vascular transport 0.5593793845750958 1.5907665973373435 0.1116621128342827 1.0 0.6443286084198793 14 P30825,P02786,Q15758,P08183,P53985,P33527,P41440 7 +Vesicle docking 0.5437478451948047 1.5902545299404676 0.1117774434575515 1.0 0.6443286084198793 15 Q13277,O43752,O60499,Q9UNK0 4 +Bone remodeling 0.6589524745031563 1.5883430739507118 0.1122087823470385 1.0 0.6450747038964281 8 Q9UBB6,O14773,Q92791 3 +Polyadenylation dependent snorna 3 end processing 0.7064284287847189 1.585055825413941 0.1129536510324822 1.0 0.6461450956219789 6 Q5RKV6,O95453,Q9NQT5 3 +Positive regulation of glucose transmembrane transport 0.8058943670379961 1.5820207965742208 0.1136448229863162 1.0 0.6461450956219789 4 P31751 1 +Regulation of protein folding 0.7411560498566918 1.5781029716895405 0.1145419556319571 1.0 0.6491723568530904 5 O14737,Q9UL15 2 +Ribonucleoside triphosphate biosynthetic process 0.4763560203966052 1.5768426185354354 0.1148317425182336 1.0 0.6502398140829311 28 P00846,Q9UJZ1,P00403,O75964,O75746,Q9UJS0 6 +Calcium ion transmembrane transport 0.4576154930379588 1.5695885087573307 0.1165108736073872 1.0 0.655982751648858 41 P16615,P98194,O95202,Q9HC07,P21796,Q13586,P78417 7 +Adenylate cyclase activating g protein coupled receptor signaling pathway 0.7386555130826232 1.5675512070142896 0.1169859068265832 1.0 0.655982751648858 5 Q9Y4G8,P04899,Q14344 3 +Bone mineralization 0.6838439274047486 1.5631305209864914 0.1180218980912179 1.0 0.6582569944899066 7 O75844,P20020,Q9UNW1 3 +Antigen processing and presentation 0.4952217112522727 1.5594068619001131 0.1189001132363554 1.0 0.6601540442652998 24 Q03518,Q9UIQ6,P50570,Q13637,Q9NZ08,P10321,P04439,O00203 8 +Mitochondrion localization 0.5534044720581327 1.5548584739732143 0.1199797791683154 1.0 0.6601540442652998 14 Q9NVT9,O75153,P07196 3 +Positive regulation of response to endoplasmic reticulum stress 0.6499942644577782 1.545808624549243 0.1221507935150487 1.0 0.6661732682774507 8 Q13794,Q07812,P46379,P51572 4 +Ceramide transport 0.6966832647687227 1.542172790940708 0.1230316101301118 1.0 0.6670290880998856 6 P08183 1 +Amyloid precursor protein catabolic process 0.5512460741840515 1.5418604519942198 0.1231075081038519 1.0 0.6670290880998856 14 Q15392,O95197,O75298 3 +Atp synthesis coupled electron transport 0.4564545232194633 1.539504717331251 0.123681127135623 1.0 0.6670290880998856 44 O43676,O96000,O95182,O14949,P00403,P14635,P03886,P20674,Q9UDW1,Q7KZN9,P13073 11 +Sterol metabolic process 0.4524907224976848 1.53884246416269 0.123842760229478 1.0 0.6670290880998856 39 P16435,O76062,Q8WTV0,P48449,P37268,Q15392,Q15800,O15118,P04114,Q16850,Q14534 11 +Diol metabolic process 0.6782112448614627 1.5376279107618875 0.1241396190583685 1.0 0.6670290880998856 7 P61457,Q13510,O15269 3 +Diol biosynthetic process 0.6782112448614627 1.5376279107618875 0.1241396190583685 1.0 0.6670290880998856 7 P61457,Q13510,O15269 3 +Membrane docking 0.4769155965888919 1.5361172877541898 0.1245096170273107 1.0 0.6673132484490486 27 O43752,P16615,Q13277,O60499,Q9UNK0 5 +Regulation of dna damage response signal transduction by p53 class mediator 0.6129385159381755 1.532853930683912 0.1253118490945557 1.0 0.6688167799301433 10 O75844,Q13794 2 +Tor signaling 0.5338687619207332 1.5285225087102396 0.1263828593561438 1.0 0.6699682071776615 15 O75844,Q8NHS3 2 +L aspartate transmembrane transport 0.7921784098254693 1.5275575091376226 0.126622438357784 1.0 0.6699682071776615 4 Q15758,O75746,Q9UJS0 3 +Neuron cellular homeostasis 0.6901136176750583 1.5131873958915452 0.1302320648976298 1.0 0.674516845868134 6 P20020,P51790 2 +Calcium ion export 0.7885235673762792 1.5130193019300446 0.1302747560158477 1.0 0.674516845868134 4 O95202,P20020 2 +Antigen processing and presentation of exogenous antigen 0.6428502087725181 1.511782571925494 0.1305891844558941 1.0 0.674516845868134 8 Q03518,O00203,Q9UIQ6,P50570 4 +Aminoglycan catabolic process 0.7878958971059956 1.5105215465969 0.1309103956656825 1.0 0.674516845868134 4 P16278 1 +Glycosaminoglycan catabolic process 0.7878958971059956 1.5105215465969 0.1309103956656825 1.0 0.674516845868134 4 P16278 1 +Regulation of glucose transmembrane transport 0.6084562988904059 1.509811758193934 0.1310914638948315 1.0 0.674516845868134 10 Q16625,P31751 2 +T cell homeostasis 0.6883917448878123 1.505580733042995 0.1321748375516191 1.0 0.674516845868134 6 Q9HCL2 1 +Negative regulation of glycoprotein metabolic process 0.7856285316611935 1.501496368813195 0.1332272251830972 1.0 0.674516845868134 4 O14734,Q9NQX7 2 +Positive regulation of mitochondrial translation 0.6403918648161504 1.500052972850703 0.1336006812503543 1.0 0.674516845868134 8 Q567V2 1 +Cristae formation 0.6233599877316938 1.497515033318625 0.1342592968533797 1.0 0.674516845868134 9 O95202,Q9NX63,Q5XKP0 3 +Calcium ion import into sarcoplasmic reticulum 0.9163436692506398 1.495619977244543 0.1347527142151756 1.0 0.674516845868134 2 O75844 1 +Regulation of regulated secretory pathway 0.5093487383400338 1.4866122675971438 0.1371172458836755 1.0 0.674516845868134 17 P04899,P16615,P09601 3 +Peripheral nervous system axon regeneration 0.9140826873384972 1.4866065233304315 0.1371187639041458 1.0 0.674516845868134 2 Q96G23 1 +Mitochondrial fusion 0.5418246874970817 1.4849653667554936 0.1375529986802115 1.0 0.674516845868134 14 Q9NX63,Q07812,P02786,Q9UJZ1,Q99536,O60313,Q9Y6C9 7 +Cholesterol efflux 0.6369042661624947 1.483394603169126 0.1379696004587431 1.0 0.674516845868134 8 O15118,P61916,P04114,Q8WTV0 4 +Antigen processing and presentation of peptide antigen via mhc class i 0.6027014866341291 1.4801662203323294 0.1388288928016174 1.0 0.674516845868134 10 Q03518,Q9UIQ6,Q9NZ08 3 +Endothelial cell proliferation 0.5259048806416956 1.4785340632444943 0.1392648866543275 1.0 0.674516845868134 15 Q8WTV0 1 +Cytosolic calcium ion transport 0.4838536594864763 1.475297226561123 0.1401326517505214 1.0 0.674516845868134 24 P21796,O95202,P78417 3 +Divalent inorganic cation homeostasis 0.455536321462093 1.474358893452287 0.14038498605157 1.0 0.674516845868134 56 P16615,P35670,Q6P4Q7,Q13586,P78417,Q8IYU8,Q9UJZ1,Q14344,Q8TAD4,Q96A33,P23634,Q07812,P98194,Q9HD20,P51572,Q12955,O00203,P20020,Q9Y3D6,O95202,Q9HC07,Q8NE01,Q9UM00 23 +Ceramide biosynthetic process 0.6181451120074045 1.47165370684153 0.1411144145875424 1.0 0.674516845868134 9 Q53H12,Q13510,Q96G23 3 +Cellular response to exogenous dsrna 0.661859151752159 1.4633126804836267 0.1433818395337245 1.0 0.6802942941607507 7 Q5KU26,P41440 2 +Regulation of glucose import 0.6613134216467089 1.4608256903800836 0.1440632836546722 1.0 0.6803856208762238 7 Q16625,P31751 2 +Negative regulation of lipid localization 0.7747774238116778 1.4582547278876852 0.144770343823033 1.0 0.6805532620928463 4 P31751 1 +Methionine metabolic process 0.7127195056982254 1.4577016080248262 0.1449228085423923 1.0 0.6805532620928463 5 Q13126 1 +Methionine biosynthetic process 0.7127195056982254 1.4577016080248262 0.1449228085423923 1.0 0.6805532620928463 5 Q13126 1 +Sulfur amino acid biosynthetic process 0.7127195056982254 1.4577016080248262 0.1449228085423923 1.0 0.6805532620928463 5 Q13126 1 +Regulation of sodium ion transport 0.5063875146751143 1.452787190923601 0.1462828494680974 1.0 0.6839535936544395 16 P50570,Q96PU5,Q12955,P27105,P23634 5 +Mitochondrial cytochrome c oxidase assembly 0.6593170833322242 1.451724441696313 0.1465782403969746 1.0 0.6839535936544395 7 O43819,Q9Y2R0,Q15070 3 +L glutamate transmembrane transport 0.659098112706299 1.4507258216533054 0.146856222260066 1.0 0.6839535936544395 7 O75915,O60831,O75746,Q9UJS0 4 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.5038029483659547 1.4497734957323762 0.1471216928289547 1.0 0.6839535936544395 17 Q13794,O95831,P46379 3 +Copper ion homeostasis 0.6752880335565379 1.4475675263200316 0.1477380385733293 1.0 0.684674199893326 6 O75880,O43819,P35670 3 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.6122997211525835 1.4426072031335953 0.1491311531099142 1.0 0.6862475958579517 9 Q8N163,P14174,Q96K76 3 +Glycolipid transport 0.7705235940530067 1.4412828803119049 0.1495047818027475 1.0 0.6862475958579517 4 P61916,Q9NZJ7,P07602 3 +Lipid translocation 0.7705235940530065 1.4412828803119038 0.1495047818027477 1.0 0.6862475958579517 4 P33527,Q4KMQ2,P08183 3 +Negative regulation of regulated secretory pathway 0.7698100239384169 1.438434865999925 0.1503107058634265 1.0 0.6862475958579517 4 P09601 1 +Manganese ion transport 0.9247172859450774 1.4358313453088962 0.151050338101079 1.0 0.6871771946259168 3 P98194,Q9HD20 2 +Manganese ion transmembrane transport 0.9247172859450774 1.4358313453088962 0.151050338101079 1.0 0.6871771946259168 3 P98194,Q9HD20 2 +Cholesterol storage 0.7677638157944816 1.4302664381663062 0.1526405634617482 1.0 0.6892440805914753 4 P04114,Q8WTV0 2 +Locomotory behavior 0.4522443650672479 1.4298729310229634 0.1527534923399078 1.0 0.6892440805914753 29 O75844,P54802,O15118,P50897 4 +Regulation of nitric oxide synthase activity 0.6706744694143663 1.4270923612545194 0.1535532740161886 1.0 0.6900113912398554 6 Q8WTV0 1 +Inositol phosphate metabolic process 0.7054107978885813 1.4266273673306826 0.1536873314688152 1.0 0.6900113912398554 5 Q9UNW1 1 +Regulation of postsynaptic membrane neurotransmitter receptor levels 0.6533694383600495 1.4245767871634276 0.1542795739972557 1.0 0.6901130979221282 7 Q13277 1 +Cerebellar cortex development 0.5599482914543356 1.423059864790406 0.1547188018212899 1.0 0.6911132541285495 12 P54802,Q5KU26 2 +Peripheral nervous system development 0.60811848009249 1.421793693284811 0.1550861509898919 1.0 0.6922717464103118 9 Q9NR77,P31751 2 +Neuron development 0.3227533524737597 1.4203833590313557 0.155496104780177 1.0 0.693136322420678 163 Q14108,Q96F07,Q9UL15,P07196,O75955,Q9NZJ7,Q13641,Q96G23,O00264,Q9Y4G8,P50897,O14949,Q8NHS3,Q9NQC3,O43464,Q9BVA1,Q32P28,Q15375,Q9NQX7,P50570,Q13277,O75503,Q96PU5,P08670,P42892,Q9UQB8,Q9UBB6,Q9Y6M7,Q9UBB4,O14976,Q05086,O94813,Q9NR77,P54802,Q9Y4F1,P41440 36 +Cellular copper ion homeostasis 0.7038371396144613 1.4199307443984064 0.1556278443073098 1.0 0.6931743563462118 5 O75880,O43819,P35670 3 +Protein lipid complex subunit organization 0.6522552624888398 1.4194859301358749 0.1557573959493319 1.0 0.6931743563462118 7 Q9Y5X1,Q8WTV0 2 +Cellular response to retinoic acid 0.622936681388985 1.4164789651722218 0.1566353185613294 1.0 0.6941163986425868 8 Q9P0J0 1 +Positive regulation of glucose import 0.919301569618885 1.4160890094050993 0.1567494455543738 1.0 0.6941163986425868 3 P31751 1 +Regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.6225554704718046 1.414648388454761 0.1571716138216967 1.0 0.6941163986425868 8 P09601 1 +Ornithine transport 0.8959948320413452 1.4145194577391331 0.1572094384329543 1.0 0.6941163986425868 2 P30825 1 +Antiviral innate immune response 0.7023783817799574 1.4137212867565188 0.157443752714725 1.0 0.6941163986425868 5 P35232,Q9NVI7,Q92667 3 +Double strand break repair via break induced replication 0.6505294307466394 1.411597120790557 0.1580686206596167 1.0 0.6941163986425868 7 P33991 1 +Sterol transport 0.4832370848420142 1.4115943327421645 0.1580694420549571 1.0 0.6941163986425868 22 Q9BZF3,Q8WTV0 2 +Protein demannosylation 0.918045282655908 1.4115091094055263 0.1580945515187233 1.0 0.6941163986425868 3 O60476 1 +Amino acid import across plasma membrane 0.667081315000478 1.411129064657575 0.1582065613754788 1.0 0.6941163986425868 6 O75915,P30825 2 +Protein targeting to lysosome 0.6204149985219156 1.4043658132249932 0.1602099455705641 1.0 0.6968856107176769 8 Q14108 1 +Positive regulation of pattern recognition receptor signaling pathway 0.6480156393123564 1.4000997113202345 0.1614834615050462 1.0 0.697056960463883 7 Q9NQC3,P41440 2 +Cartilage development involved in endochondral bone morphogenesis 0.7601571379535309 1.3998817863575506 0.1615487210551021 1.0 0.697056960463883 4 O75844 1 +Positive regulation of calcium ion transmembrane transporter activity 0.6193557300703599 1.3992747184362264 0.1617306178929449 1.0 0.697056960463883 8 P78417 1 +Sodium ion transport 0.473320222967706 1.396894400431403 0.1624453287236256 1.0 0.6979051991410457 24 Q9Y6M7,P50570,Q4KMQ2,Q96PU5,Q12955,Q6P4Q7,P27105,P23634 8 +Regulation of caveolin mediated endocytosis 0.8914728682170505 1.396508977198413 0.162561279166872 1.0 0.6979355656126254 2 Q13432 1 +Nuclear transcribed mrna catabolic process exonucleolytic 0.5407099300191933 1.3954617540655108 0.1628766402962949 1.0 0.6988214620476909 13 Q5RKV6,Q6PGP7,Q9NQT5,Q96B26,Q969T7 5 +Positive regulation of oxidoreductase activity 0.602740771223521 1.3949817036002363 0.1630213569986582 1.0 0.6989745139541134 9 P16435,P04899,P00374,Q8WTV0 4 +Neuron projection guidance 0.4925080410064323 1.3899024413476229 0.1645585041805999 1.0 0.7032082178799407 18 O94813,Q9BVA1,Q15375,P42892,O00264 5 +Regulation of systemic arterial blood pressure 0.6160945164636291 1.38359041241209 0.1664839056879077 1.0 0.7059899339022179 8 P42785 1 +Negative regulation of protein secretion 0.6159062374132566 1.3826844531569007 0.1667616409686338 1.0 0.7059899339022179 8 Q6WKZ4,Q16836,Q16850 3 +Positive regulation of fatty acid beta oxidation 0.8879198966408192 1.3823627897838775 0.1668603353918658 1.0 0.7059899339022179 2 P31751 1 +Positive regulation of fatty acid oxidation 0.8879198966408192 1.3823627897838775 0.1668603353918658 1.0 0.7059899339022179 2 P31751 1 +Positive regulation of lipid catabolic process 0.8879198966408192 1.3823627897838775 0.1668603353918658 1.0 0.7059899339022179 2 P31751 1 +Positive regulation of peptidase activity 0.4344615224492182 1.3788995305792722 0.1679257329380599 1.0 0.7076949034404759 39 Q07812,Q96HY6,Q96F07,Q96A26,Q9UL46,Q9BXK5,O43464,P51572,O14737,O95831,Q9NZJ7,Q9P0J0,Q13794,O75915,Q9Y3D6 15 +Regulation of programmed necrotic cell death 0.6142881755268206 1.374896646847053 0.169163488992238 1.0 0.7115078506825758 8 Q13510,P16989 2 +Lymphocyte homeostasis 0.5814511905433124 1.3701436317529638 0.1706420700545612 1.0 0.7146760030795101 10 Q13794,Q9HCL2 2 +Cellular response to xenobiotic stimulus 0.4652835273679594 1.369253097463596 0.1709201735914023 1.0 0.7146760030795101 25 O43169,P07099,P78417 3 +Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.5810005207045315 1.3678015991921504 0.171374187015004 1.0 0.7154618486107358 10 P14174,P46379 2 +Mitotic dna replication 0.5809582610165585 1.367581967626803 0.1714429640352714 1.0 0.7154618486107358 10 O75844,P33991 2 +Nuclear pore complex assembly 0.6126262372957884 1.3668939211331506 0.1716585576624076 1.0 0.7154822407529767 8 Q8N1F7,Q9NQC3,Q9BTX1 3 +Retrograde transport endosome to golgi 0.432532519330806 1.366761398628012 0.1717001057794827 1.0 0.7154822407529767 31 O43752,O95249,Q9BVK6,P49257,P51151,Q4J6C6,Q92538,P53367,O75503,Q13190,O60499,Q9UNH7,P40616,O60749 14 +Srp dependent cotranslational protein targeting to membrane 0.5805341231453774 1.365377480276834 0.1721344381186016 1.0 0.7154822407529767 10 P49458,Q9UGP8 2 +Folate transmembrane transport 0.8833979328165287 1.36436592175171 0.1724524277633929 1.0 0.7154822407529767 2 P41440 1 +Folic acid transport 0.8833979328165287 1.36436592175171 0.1724524277633929 1.0 0.7154822407529767 2 P41440 1 +Tetrapyrrole biosynthetic process 0.5491377405532583 1.3620628681049558 0.1731780454601392 1.0 0.715784010031192 12 Q9P0S9,P22830,P50336,O75027,Q7KZN9 5 +Regulation of retrograde protein transport er to cytosol 0.6902351283150665 1.361970034211222 0.1732073421943187 1.0 0.715784010031192 5 Q9GZP9,Q8NBM4,P51572 3 +Membrane lipid catabolic process 0.5650541818705508 1.3615638949554103 0.1733355561139058 1.0 0.715784010031192 11 P06865,P50897,P06280 3 +Positive regulation of transporter activity 0.4850270662724349 1.3564731662831655 0.1749486675073106 1.0 0.7177868102246682 19 P08183,Q13586,P78417 3 +Antigen processing and presentation of endogenous peptide antigen 0.6546166090688139 1.3556474031862165 0.1752113817332679 1.0 0.7177868102246682 6 Q03518,Q9NZ08,P10321 3 +Antigen processing and presentation of endogenous antigen 0.6546166090688139 1.3556474031862165 0.1752113817332679 1.0 0.7177868102246682 6 Q03518,Q9NZ08,P10321 3 +Lipid droplet formation 0.880813953488373 1.354086197633346 0.175708879118561 1.0 0.7178418834607879 2 Q14534 1 +Clathrin dependent endocytosis 0.5201290401641524 1.3530410313455696 0.1760425225108364 1.0 0.7179694288324492 14 Q13432,Q5VW38 2 +Intrinsic apoptotic signaling pathway in response to dna damage 0.4714290600229081 1.3529358599278845 0.1760761220163198 1.0 0.7179694288324492 23 Q8N163,P09601,P46379,Q96K76 4 +Aerobic respiration 0.4344238402989429 1.3520920608005156 0.1763458667634889 1.0 0.7181556581664321 95 P00846,O95182,P00403,P03886,Q7KZN9,O43676,O14949,P14406,Q9UJZ1,O75964,P14635,Q13423,P13073,P22695,O95168,P20674,Q9UDW1,O96000,Q9BSK2,Q15070 20 +Mitochondrion distribution 0.6874211603183059 1.349963580298213 0.1770276653879006 1.0 0.7192018648843569 5 Q9NVT9,O75153 2 +Negative regulation of proteolysis involved in cellular protein catabolic process 0.4529692236703174 1.3477351173107284 0.1777435928969957 1.0 0.7193307166029721 27 Q8N163,Q96HY6,P46379,Q9UL15,Q9GZU8,Q92530 6 +Negative regulation of protein polymerization 0.4706102756141409 1.3469123308100537 0.1780084696971269 1.0 0.7193307166029721 23 P45880,Q9NUQ9,O94813 3 +Secondary alcohol metabolic process 0.4342414945305151 1.346862299394134 0.1780245856082769 1.0 0.7193307166029721 43 P16435,O76062,Q8WTV0,P48449,P37268,Q15392,Q15800,O15118,P04114,Q16850,Q14534 11 +Regulation of t cell mediated cytotoxicity 0.7463094805538764 1.34450483435645 0.1787851941975526 1.0 0.7193307166029721 4 Q9NUQ9,O15400 2 +Positive regulation of t cell mediated cytotoxicity 0.7463094805538764 1.34450483435645 0.1787851941975526 1.0 0.7193307166029721 4 Q9NUQ9,O15400 2 +Myeloid leukocyte cytokine production 0.63571136710958 1.3437134121429433 0.1790410785509788 1.0 0.7193307166029721 7 P09601 1 +Collagen biosynthetic process 0.7460636692112371 1.3435212539586232 0.1791032486268866 1.0 0.7193307166029721 4 P08670 1 +Negative regulation of blood pressure 0.745769024747273 1.342342252939856 0.1794850492759545 1.0 0.71960256221417 4 P42785 1 +Negative regulation of muscle cell apoptotic process 0.685105789137274 1.340081015701532 0.1802190073349046 1.0 0.71960256221417 5 Q8NDZ4 1 +Phagocytosis recognition 0.896651892564392 1.3335257963271991 0.1823593158117891 1.0 0.723188670643557 3 Q8WTV0 1 +Regulation of erad pathway 0.6829180692491249 1.3307405805363246 0.183274385399454 1.0 0.724887085767563 5 P46379 1 +Regulation of cellular response to osmotic stress 0.6824043782502272 1.328547019848325 0.1839974610645596 1.0 0.7263356711558655 5 O95202 1 +Bone resorption 0.6315335443996011 1.3245295424968393 0.1853272382968682 1.0 0.7263356711558655 7 Q9UBB6,O14773 2 +Ovulation cycle process 0.8730620155038771 1.3232684667616317 0.1857461142425835 1.0 0.7263356711558655 2 O94813 1 +Plasma membrane raft assembly 0.8727390180878453 1.321985167379375 0.1861730901262226 1.0 0.7263356711558655 2 P41440 1 +Positive regulation of heterotypic cell cell adhesion 0.8727390180878453 1.321985167379375 0.1861730901262226 1.0 0.7263356711558655 2 P41440 1 +Regulation of synaptic transmission dopaminergic 0.8727390180878453 1.321985167379375 0.1861730901262226 1.0 0.7263356711558655 2 P41440 1 +Plasma membrane raft organization 0.8727390180878453 1.321985167379375 0.1861730901262226 1.0 0.7263356711558655 2 P41440 1 +Positive regulation of toll like receptor 3 signaling pathway 0.8727390180878453 1.321985167379375 0.1861730901262226 1.0 0.7263356711558655 2 P41440 1 +Glutathione metabolic process 0.4770933169689716 1.3209470410990989 0.1865190231080529 1.0 0.7268866155789018 20 Q9H7Z7 1 +Regulation of oxidoreductase activity 0.4839819452666214 1.3173449528208567 0.187723023558993 1.0 0.7268866155789018 17 P04899,Q8WTV0,P06280,Q15070 4 +Regulation of bone mineralization 0.6791321503392949 1.3145708997871104 0.188654155483261 1.0 0.7268866155789018 5 O75844,P20020 2 +Centromere complex assembly 0.6016532116528289 1.3139658575454063 0.1888576942017152 1.0 0.7268866155789018 8 Q6IPU0,P50748,Q9NRZ9 3 +Protein localization to lysosome 0.5561931450427452 1.3135198509312949 0.189007836318622 1.0 0.7268866155789018 11 Q9NQC3,Q14108 2 +Regulation of phosphatidylinositol 3 kinase signaling 0.6780895319750846 1.3101166807529887 0.1901563662642678 1.0 0.7268866155789018 5 Q10713,Q8NDZ4 2 +Protein containing complex remodeling 0.8691860465116139 1.3078733964827094 0.1909162542646634 1.0 0.7268866155789018 2 Q8WTV0 1 +Retrograde transport vesicle recycling within golgi 0.6772223509887314 1.3064115895461528 0.1914126267082028 1.0 0.7268866155789018 5 Q9Y2V7,Q9UP83,P83436 3 +Sphingolipid translocation 0.8682170542635537 1.3040262306253056 0.1922246390144004 1.0 0.7268866155789018 2 P08183 1 +Xenobiotic transport across blood brain barrier 0.8682170542635537 1.3040262306253056 0.1922246390144004 1.0 0.7268866155789018 2 P08183 1 +Sterol biosynthetic process 0.4422903517506168 1.3034584602271913 0.1924182892675963 1.0 0.7268866155789018 28 P16435,P48449,P37268,Q14534,Q15392,Q15800,Q16850,O76062 8 +Positive regulation of mitochondrion organization 0.4682567569189629 1.303277035490573 0.1924801982820667 1.0 0.7268866155789018 22 P21796,Q96A26,O14737 3 +Membrane lipid biosynthetic process 0.4607321571478432 1.3026700576007877 0.1926874286351909 1.0 0.7268866155789018 24 Q8NBX0,O95470,Q13510,Q06136,Q53H12,O15269,Q96G23 7 +Extrinsic apoptotic signaling pathway via death domain receptors 0.5537774770108163 1.3004001108527838 0.1934638719661126 1.0 0.7268866155789018 11 O95817,P09601,Q13794 3 +Heme transport 0.8669250645994726 1.2988977239990156 0.1939790308760953 1.0 0.7268866155789018 2 O15173 1 +Iron coordination entity transport 0.8669250645994726 1.2988977239990156 0.1939790308760953 1.0 0.7268866155789018 2 O15173 1 +Positive regulation of mitochondrial membrane potential 0.7346275668243207 1.2977465816806226 0.1943744311200101 1.0 0.7268866155789018 4 P31751 1 +Negative regulation of axonogenesis 0.674967253132708 1.2967750483029004 0.19470859832728 1.0 0.7268866155789018 5 Q15375,Q8N0X7,Q9NQC3 3 +Leukotriene metabolic process 0.734324499030382 1.2965332184226217 0.1947918432537028 1.0 0.7268866155789018 4 O14880,P33527,P09960 3 +Sphingosine biosynthetic process 0.7339274720221015 1.2949436652610868 0.1953396638691231 1.0 0.7268866155789018 4 Q13510 1 +Neutral amino acid transport 0.7335714404849121 1.293518229950577 0.1958318831739742 1.0 0.7268866155789018 4 Q96NB2 1 +T cell mediated cytotoxicity 0.6405105969339023 1.292690888636431 0.1961179902948959 1.0 0.7268866155789018 6 Q9NUQ9,O15400 2 +Calcium ion transport 0.4359058649886105 1.291596659497079 0.1964968615027424 1.0 0.7268866155789018 56 O75844,P04899,P16615,P98194,O95202,Q9HC07,P21796,Q13586,P78417 9 +Chromosome organization involved in meiotic cell cycle 0.4777325502754314 1.2894666285351322 0.1972359107844745 1.0 0.7268866155789018 18 Q92791,P46379,Q9BTX1,Q9BXW9 4 +Phosphatidylinositol dephosphorylation 0.7324837634522405 1.28916345196594 0.1973412680797432 1.0 0.7268866155789018 4 Q10713 1 +Phospholipid dephosphorylation 0.7324837634522405 1.28916345196594 0.1973412680797432 1.0 0.7268866155789018 4 Q10713 1 +Central nervous system neuron development 0.5655558322085931 1.2873487157025554 0.1979727708293115 1.0 0.7268866155789018 10 Q9Y4G8,O94813,O14949 3 +Pigment granule localization 0.6721629485936029 1.2847888759630748 0.19886607066418 1.0 0.7268866155789018 5 Q15907,Q13561,Q9H267,P62820 4 +Inorganic anion transmembrane transport 0.5354638004827049 1.2845876292119012 0.198936423878169 1.0 0.7268866155789018 12 Q9UHG3,Q4KMQ2,P51790,Q9UBX3 4 +Skin epidermis development 0.5508036399597628 1.2842367955714475 0.1990591141957529 1.0 0.7268866155789018 11 O75844,Q08J23 2 +Positive regulation of mammary gland epithelial cell proliferation 0.8630490956072376 1.2835197472207671 0.1993100457541876 1.0 0.7268866155789018 2 Q9NQC3 1 +Chloride transmembrane transport 0.6224165063560794 1.2826062880054852 0.1996300460897444 1.0 0.7268866155789018 7 Q9UHG3,Q4KMQ2,P51790 3 +Lipid localization 0.4374647438946978 1.2807243354800155 0.2002905089223572 1.0 0.7268866155789018 71 Q99720,Q14108,Q9H6V9,Q9H2V7,P07602,P31751,Q9BZF3,P04114,Q8WTV0,Q9UJZ1,O15118,O43772,P08183,Q14534,P50416,Q9P260,P23786,Q9Y679,P14174 19 +Regulation of lymphocyte apoptotic process 0.5798834833550714 1.280543453720387 0.2003540724994008 1.0 0.7268866155789018 9 Q9HCL2 1 +Ubiquitin dependent erad pathway 0.41829935074372 1.278832473885288 0.2009560557193923 1.0 0.7268866155789018 34 Q9UBV2,P46379,Q92575,P51572,Q8IXB1,Q96A33 6 +Regulation of macroautophagy 0.4302620573943205 1.278239936225446 0.2011648387694284 1.0 0.7268866155789018 48 P21796,Q9Y487,Q93050,O15118 4 +Golgi vesicle transport 0.3830894100743653 1.2775072021895597 0.20142323935159 1.0 0.7268866155789018 130 O43752,Q6NUQ1,Q8N2H4,Q96PC5,O15127,Q12981,Q5BJH7,O60749,Q15363,P24390,Q9UP83,Q96RQ1,Q9BSR8,O43731,Q8WU17,Q5JRA6,P50570,P98194,Q4J6C6,Q8NHH9,P51572,Q9Y3B3,O14653,Q9Y282,O95249,O95070,Q9BVK6,O14976,Q9P2W9,P83436,O60499,P40616 32 +Progesterone receptor signaling pathway 0.7288360553815669 1.2745584200588231 0.2024655825513939 1.0 0.7268866155789018 4 Q05086,Q969T9 2 +Embryonic heart tube development 0.6696221239242708 1.2739265317788648 0.2026894545201325 1.0 0.7268866155789018 5 P42892 1 +Glycosylation 0.4323685106102533 1.271225595643919 0.2036484032632797 1.0 0.7268866155789018 53 Q9UP83,Q9BT22,Q9BV10,Q9NR45,Q9HC07,O15294,O75503,P83436,O60476,O15118,O60762,O60502,Q86YN1,O43505,P46977,Q86SF2,Q9BXS4 17 +Trna catabolic process 0.5780090085171271 1.2711287142044103 0.2036828615987194 1.0 0.7268866155789018 9 Q96B26,Q9NQT5,Q08J23,Q99575 4 +Mitophagy 0.5196110054642152 1.2710278164077058 0.2037187529645352 1.0 0.7268866155789018 13 P21796 1 +Regulation of axon guidance 0.8598191214470301 1.2707139805660177 0.2038304200821623 1.0 0.7268866155789018 2 O94813 1 +Positive regulation of glucose metabolic process 0.6684959149991777 1.2691112130901527 0.2044014015751927 1.0 0.7268866155789018 5 Q13794,P31751 2 +Positive regulation of cellular carbohydrate metabolic process 0.6684959149991777 1.2691112130901527 0.2044014015751927 1.0 0.7268866155789018 5 Q13794,P31751 2 +Response to cell cycle checkpoint signaling 0.8785480111598962 1.2675992072691638 0.2049411151826656 1.0 0.7268866155789018 3 O75844 1 +Ribonucleoside metabolic process 0.5917158663711096 1.2659128906787604 0.2055442707619235 1.0 0.7268866155789018 8 Q13126,P49902 2 +Purine ribonucleoside metabolic process 0.5917158663711096 1.2659128906787604 0.2055442707619235 1.0 0.7268866155789018 8 Q13126,P49902 2 +Nuclear transcribed mrna catabolic process exonucleolytic 3 5 0.576952934741935 1.2658227550327852 0.2055765464316863 1.0 0.7268866155789018 9 Q5RKV6,Q6PGP7,Q9NQT5,Q96B26 4 +Regulation of glycoprotein metabolic process 0.531932533475655 1.2645285958911958 0.2060403635792862 1.0 0.7268866155789018 12 O14734,Q9NQX7,Q9BXS4 3 +Branching morphogenesis of a nerve 0.8582041343669278 1.2643144442134222 0.2061171872109606 1.0 0.7268866155789018 2 Q9NQC3 1 +Regulation of neurotransmitter transport 0.5055199697238119 1.2635980135024325 0.2063743469703594 1.0 0.7268866155789018 14 O75955,P16615,P41440 3 +Steroid biosynthetic process 0.4278746237310039 1.2563494259633567 0.2089893092533663 1.0 0.7268866155789018 48 Q53GQ0,Q9H3P7,P16435,O76062,P48449,P37268,Q14534,Q15392,Q13510,Q15800,Q9BZF3,Q16850,O14734 13 +Purine containing compound transmembrane transport 0.5594630671040288 1.2555196032528917 0.2092901963161235 1.0 0.7268866155789018 10 Q8TDW0,Q86VD7,Q8TB61,P41440 4 +Regulation of mammary gland epithelial cell proliferation 0.7239166211957061 1.254861245891446 0.2095291345405168 1.0 0.7268866155789018 4 Q92766,Q9NQC3 2 +Negative regulation of mononuclear cell migration 0.8546511627906994 1.250243794159851 0.211210503342395 1.0 0.7282729028643098 2 O94813 1 +Cellular response to biotic stimulus 0.4246328508163365 1.2479788511308985 0.2120388022624166 1.0 0.7286688829876297 30 O75844,Q8WTV0,P08670,Q9NUQ9,Q96A33,P14174 6 +Positive regulation of cell adhesion molecule production 0.8730210016155164 1.2474960517967462 0.2122156670252866 1.0 0.7286688829876297 3 Q5KU26,P41440 2 +Cell adhesion molecule production 0.8730210016155164 1.2474960517967462 0.2122156670252866 1.0 0.7286688829876297 3 Q5KU26,P41440 2 +Positive regulation of small gtpase mediated signal transduction 0.6303913273020694 1.2474408570631372 0.2122358933997268 1.0 0.7286688829876297 6 Q96RT1 1 +Regulation of chondrocyte differentiation 0.7218317652730704 1.246513899456296 0.2125757895767344 1.0 0.7286688829876297 4 P16435,Q92896 2 +Regulation of cartilage development 0.7218317652730704 1.246513899456296 0.2125757895767344 1.0 0.7286688829876297 4 P16435,Q92896 2 +Bile acid metabolic process 0.5575446519901597 1.2454883508153962 0.2129522949344409 1.0 0.7292381424501045 10 O15118,Q9BZF3 2 +Inner ear receptor cell development 0.6141852647109455 1.2446952230964747 0.2132438025553968 1.0 0.7292381424501045 7 P54802 1 +Cellular respiration 0.4110680622945458 1.241782321601151 0.2143168870209257 1.0 0.7298897011835311 109 P00846,O95182,P00403,P03886,Q7KZN9,Q9UJS0,O43676,O14949,P14406,Q9UJZ1,O75964,P14635,Q13423,P13073,P22695,O95168,O75746,P20674,Q9UDW1,O96000,O43819,Q9BSK2,Q15070 23 +Phosphatidylglycerol metabolic process 0.5017825148200831 1.240650863302574 0.2147347535072967 1.0 0.7298897011835311 14 Q9HCL2 1 +Regulation of skeletal muscle tissue development 0.6288624508645348 1.240599278908008 0.2147538184761528 1.0 0.7298897011835311 6 P41440,P16989 2 +Cell cycle dna replication initiation 0.6285193857420726 1.239063940710282 0.2153218196297959 1.0 0.7310449490609067 6 P33991 1 +Organic hydroxy compound catabolic process 0.5561663593929117 1.2382787920669978 0.2156127047282381 1.0 0.7312579033375695 10 Q10713,P30837,Q8WTV0 3 +Necrotic cell death 0.4876266688534575 1.2358792436379156 0.216503453450892 1.0 0.7323414968972127 15 Q13510,O15294,P00403,P16989 4 +Regulation of hormone metabolic process 0.660194588137569 1.2336081016603049 0.2173489726278967 1.0 0.7338908524850651 5 O75844 1 +Positive regulation of membrane protein ectodomain proteolysis 0.8501291989664115 1.232353376737038 0.2178171089653129 1.0 0.7342515106543303 2 Q9Y5X1 1 +Regulation of membrane protein ectodomain proteolysis 0.8501291989664115 1.232353376737038 0.2178171089653129 1.0 0.7342515106543303 2 Q9Y5X1 1 +Low density lipoprotein particle clearance 0.5127241147444354 1.230236859299436 0.218608420871345 1.0 0.7344797311073974 13 Q6PIU2,P09601,P04114,Q8WTV0 4 +Response to corticosterone 0.8491602067183432 1.2285224474078291 0.2192509080906153 1.0 0.7350409627933285 2 P07196 1 +Intrinsic apoptotic signaling pathway by p53 class mediator 0.4684962754919689 1.2264064374987085 0.2200457647049447 1.0 0.736001301553902 18 Q13794,P46379 2 +Fatty acid derivative biosynthetic process 0.4720209153868296 1.225793089946984 0.2202765482146744 1.0 0.7361068294481664 16 Q53GQ0,Q9UMR5,P50897 3 +Regulation of sodium ion transmembrane transport 0.4986820742182688 1.2215975230956864 0.2218598657740704 1.0 0.739148513311742 14 P27105,Q96PU5,P50570,P23634 4 +Positive regulation of membrane potential 0.6243602277981875 1.2204461130390174 0.2222958055655488 1.0 0.7394605002378776 6 P31751 1 +Cellular response to lipoprotein particle stimulus 0.7151028487434781 1.219576195007124 0.2226255751051948 1.0 0.7397770536154998 4 O15118 1 +Positive regulation of cation channel activity 0.6080180613155628 1.216259205323228 0.2238861964833014 1.0 0.7415809028673813 7 P78417 1 +Peroxisome fission 0.6540575493048987 1.2073550792290992 0.2272954272877103 1.0 0.7450803881578313 5 O14734,Q9Y3D6,P40855,O96011 4 +Regulation of release of cytochrome c from mitochondria 0.5366388911732952 1.2070866106428275 0.2273987907435528 1.0 0.7450803881578313 11 O14737,Q96A26,Q07812,Q13794 4 +Response to progesterone 0.710946011450366 1.2029396152869145 0.2289996887590291 1.0 0.7477778935024841 4 Q969T9 1 +Retinol metabolic process 0.5643864211465974 1.202600757147824 0.229130854554872 1.0 0.7478252432264408 9 P41247,Q9BTZ2,Q6NUM9,Q9HBH5,Q8NBN7 5 +Positive regulation of protein localization to membrane 0.4295638135311732 1.200141786475573 0.2300842792152133 1.0 0.7487284025313639 28 P27105,O14737,P98194,P31751 4 +Pore complex assembly 0.5206075366901053 1.200079627031564 0.2301084170026188 1.0 0.7487284025313639 12 Q8N1F7,Q4KMQ2,Q9NQC3,Q9BTX1 4 +Regulation of anion transmembrane transport 0.6516656968999919 1.1971229203596776 0.2312586474804829 1.0 0.7494674594172517 5 P08183 1 +Cerebellar purkinje cell layer development 0.6029974960044089 1.1930939896161168 0.2328325651530096 1.0 0.7505842964512147 7 P54802 1 +Intracellular distribution of mitochondria 0.8579913613074648 1.1929125746246252 0.2329036139846281 1.0 0.7505842964512147 3 O75153 1 +Synaptic transmission gabaergic 0.708115737193626 1.1916149566918424 0.2334122576669617 1.0 0.7514678913336136 4 Q13641 1 +Endosome organization 0.4586694846372903 1.1912490710024728 0.2335558207423509 1.0 0.7515526159430068 20 P51790,Q14108 2 +Steroid metabolic process 0.4280522544934759 1.1882952095999126 0.2347171243687349 1.0 0.7539821540034571 69 Q53GQ0,Q9H3P7,P16435,O76062,P38435,Q8WTV0,P48449,P37268,O95470,Q14534,Q15392,Q13510,Q15800,Q9BZF3,O15118,Q16850,O14734 17 +Circulatory system process 0.4276939923142467 1.1875728528385046 0.2350017384526852 1.0 0.754312039800557 66 P16615,P42785,P33527,Q9HB40,P78417,P04899,Q9UIQ6,P53985,Q9NZ08,P09601,Q16625,Q96PU5,P08183,P42892,O75844,P30825,O94813,O75787,P41440 19 +Second messenger mediated signaling 0.4488280259133534 1.1859497323051051 0.2356421514906261 1.0 0.7556109009779459 23 O75844,Q9Y4G8,P16615,P51572,P78417,P23634 6 +Regulation of dna primase activity 0.8543649983104515 1.1797648013089863 0.2380937725824186 1.0 0.7591558659089954 3 Q9BRX5 1 +Lysosomal transport 0.4071502670316423 1.179576061919534 0.2381688683842417 1.0 0.7591558659089954 34 Q14108,O14976,P07602,O15118,Q9UNK0 5 +Chromatin remodeling at centromere 0.7041953796290209 1.1759331299690463 0.239621598690354 1.0 0.760908466499093 4 Q6IPU0,Q9NRZ9 2 +Interferon beta production 0.5589374869113403 1.1751462973830815 0.2399361909383413 1.0 0.760908466499093 9 P41440 1 +Positive regulation of interferon beta production 0.5589374869113403 1.1751462973830815 0.2399361909383413 1.0 0.760908466499093 9 P41440 1 +Mitochondrial electron transport ubiquinol to cytochrome c 0.703395568735327 1.172734543042665 0.2409022745525699 1.0 0.7618073901736426 4 Q9UDW1 1 +Negative regulation of ion transmembrane transporter activity 0.5720865289792461 1.1707365877219127 0.2417046737117538 1.0 0.7618987121868883 8 P78417 1 +Amyloid beta formation 0.5580554100994761 1.1707000897425843 0.2417193491441667 1.0 0.7618987121868883 9 O95197,O75298 2 +Regulation of mitochondrial membrane permeability 0.4636243069989164 1.16993652689343 0.2420265130877932 1.0 0.7618987121868883 16 P45880 1 +Neuromuscular process 0.452539505535095 1.1673561341017138 0.2430665781365995 1.0 0.7631995666437705 21 O75844,O14773,P78417 3 +Positive regulation of fibroblast proliferation 0.6124375404428908 1.1670447668441115 0.2431922913603714 1.0 0.7631995666437705 6 P14174 1 +Response to nitric oxide 0.5972970479617677 1.1667779074792026 0.243300071069147 1.0 0.7631995666437705 7 O95831,P50570 2 +Cellular response to reactive nitrogen species 0.5972970479617677 1.1667779074792026 0.243300071069147 1.0 0.7631995666437705 7 O95831,P50570 2 +Response to muramyl dipeptide 0.850056740390605 1.1641579396454589 0.2443600118610951 1.0 0.7643633919965375 3 P08670 1 +Positive regulation of protein kinase activity 0.411423383852069 1.1638162882380945 0.244498469799947 1.0 0.7643633919965375 40 Q9Y4G8,Q8NDZ4,P14174,Q9Y5X1,Q13432,P14635,Q99627,P12956,P23634 9 +Cobalamin transport 0.8320413436692531 1.161025292472478 0.2456316138924659 1.0 0.765906508968564 2 P33527 1 +Positive regulation of bone mineralization 0.8317183462532307 1.159755448091445 0.246148387768768 1.0 0.765906508968564 2 P20020 1 +Purinergic nucleotide receptor signaling pathway 0.8317183462532267 1.1597554480914307 0.2461483877687738 1.0 0.765906508968564 2 P04899 1 +Negative regulation of cell volume 0.8317183462532165 1.15975544809139 0.2461483877687904 1.0 0.765906508968564 2 P51790 1 +Regulation of tube size 0.5697680709352196 1.1594788625686634 0.24626104757944 1.0 0.765906508968564 8 Q9HB40 1 +Regulation of multicellular organism growth 0.4755540251052231 1.1587210867151765 0.246569892697158 1.0 0.7664951562506223 15 Q9HCL2 1 +Peptidyl glutamic acid modification 0.6994928624832297 1.15713102148234 0.2472188342342927 1.0 0.7678251052950689 4 Q8N0U8 1 +Immune response regulating cell surface receptor signaling pathway 0.4448334053134732 1.1563063203270858 0.2475558840362692 1.0 0.7679343359977917 23 Q07812,P46379,Q9UJZ1,Q08722,Q9NR50,Q96IZ0 6 +Xenobiotic export 0.83010335917311 1.1534084916451035 0.2487427576994341 1.0 0.7698894625076642 2 P08183 1 +Mucopolysaccharide metabolic process 0.5537849314615368 1.1491680237320614 0.2504867033913789 1.0 0.7730475535574092 9 O43505,Q8NCH0,P16278,O94923 4 +Molting cycle 0.5251349606232917 1.144272989143981 0.2525104414873569 1.0 0.775076311467598 11 O75844 1 +Retinal metabolic process 0.6955568196221491 1.1414019964047812 0.2537026742939896 1.0 0.7762454139496293 4 Q9BTZ2,Q8NBN7 2 +Glycosphingolipid metabolic process 0.565100477789575 1.1368077393503666 0.2556186672748679 1.0 0.7780226292649114 8 P06280,P16278 2 +Amino acid salvage 0.8417941484383358 1.134270927823348 0.2566809200622657 1.0 0.7793238845945248 3 Q13126 1 +L methionine salvage from methylthioadenosine 0.8417941484383358 1.134270927823348 0.2566809200622657 1.0 0.7793238845945248 3 Q13126 1 +Protein localization to vacuole 0.4716580617724748 1.133780686777107 0.2568865542054075 1.0 0.7793238845945248 15 Q9NQC3,Q14108 2 +Negative regulation of synapse organization 0.8249354005167977 1.133124550227712 0.2571619529850637 1.0 0.7793238845945248 2 Q15375 1 +Insulin receptor signaling pathway 0.4448035184969414 1.1324715486068522 0.2574362393130607 1.0 0.7793238845945248 22 Q8TBX8,P04899,P43490,Q9HCD5,O15294,P31751,Q9UQB8 7 +Early endosome to golgi transport 0.5897466220963273 1.1319058521583256 0.2576740180700356 1.0 0.7793238845945248 7 O60499,Q9BVK6,Q13190,O60749 4 +Response to muscle activity 0.6361062672977915 1.1305805865349912 0.2582316623376992 1.0 0.7793238845945248 5 Q9UDX5 1 +Regulation of cell cell adhesion mediated by cadherin 0.6927698542035476 1.1302702644502196 0.2583623602396914 1.0 0.7793238845945248 4 P41440 1 +Positive regulation of cell cell adhesion mediated by cadherin 0.6927698542035476 1.1302702644502196 0.2583623602396914 1.0 0.7793238845945248 4 P41440 1 +Microtubule organizing center organization 0.399298978278378 1.1296940743520552 0.2586051549899752 1.0 0.7793413462556377 32 O94927,Q9H6D7,P53985 3 +Positive regulation of skeletal muscle tissue development 0.6922608983272153 1.1282379128934832 0.2592194563847756 1.0 0.7797262859814227 4 P41440 1 +Positive regulation of muscle tissue development 0.6922608983272153 1.1282379128934832 0.2592194563847756 1.0 0.7797262859814227 4 P41440 1 +Phosphatidylethanolamine metabolic process 0.6921350759654207 1.1277355078005844 0.2594316371108718 1.0 0.7799984961916924 4 Q8NCC3 1 +Lens development in camera type eye 0.6353571307801383 1.1273785029243768 0.2595824840522005 1.0 0.7800861335089571 5 P08670,Q15648,P28289 3 +Atp transport 0.5874568356853163 1.1213282814593462 0.2621481514841606 1.0 0.7827134816754094 7 Q86VD7,Q08722 2 +Regulation of cytosolic calcium ion concentration 0.4424396553180161 1.115196608014073 0.2647661793137721 1.0 0.7827134816754094 22 Q07812,O95202,P51572,Q14344,P20020,P78417,P23634 7 +Positive regulation of protein targeting to membrane 0.5465126489605894 1.1124820552440902 0.2659309414684614 1.0 0.7827134816754094 9 P31751 1 +Regulation of protein targeting to membrane 0.5465126489605894 1.1124820552440902 0.2659309414684614 1.0 0.7827134816754094 9 P31751 1 +Glycoside metabolic process 0.5464261903396856 1.112045801010687 0.2661184582426736 1.0 0.7827134816754094 9 Q9NUJ1,P06280 2 +Neuron death 0.4192812417342089 1.111865815299836 0.2661958486821205 1.0 0.7827134816754094 63 Q99720,P50897,Q96A26,Q9UL15,P09601,P31751,O95831,Q9UMX5 8 +Plasma lipoprotein particle clearance 0.4807794817665437 1.1113372245368611 0.266423222220383 1.0 0.7830228585202456 14 Q6PIU2,P09601,P04114,Q8WTV0 4 +Membrane raft organization 0.5593822496867731 1.1090248534089118 0.2674194605033393 1.0 0.7841531298382456 8 O15118,P50897 2 +Negative regulation of transporter activity 0.5453805759631342 1.1067696866788008 0.2683935173852281 1.0 0.7841796698282537 9 P78417 1 +Photoreceptor cell differentiation 0.6304708052601888 1.1064987334252956 0.2685107119288958 1.0 0.7841796698282537 5 P54802,Q8NBN7 2 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.8338067230515314 1.105442434449326 0.2689679250986954 1.0 0.7841796698282537 3 Q03518 1 +Cell motility involved in cerebral cortex radial glia guided migration 0.81750645994832 1.1040418274000137 0.2695749938845972 1.0 0.7844999419286854 2 O94901 1 +Endoplasmic reticulum calcium ion homeostasis 0.5447960986557234 1.1038203439049 0.2696710780758562 1.0 0.7844999419286854 9 Q07812,P16615,Q9UM00,P51572,Q96A33,Q9Y3D6 6 +Golgi organization 0.4092143525339068 1.0979617261316563 0.27222120240852 1.0 0.7864738518469068 46 Q15363,O43752,Q9UP83,Q9BVK6,P50570,O14976,Q9UL15,O75396,Q8NHH9,Q9P2W9,P83436,Q9Y3B3,Q13190,Q9BSR8,P40616 15 +Proteasome assembly 0.6844466981592434 1.0970574329577727 0.272616286499554 1.0 0.7864738518469068 4 O95456 1 +Negative regulation of protein exit from endoplasmic reticulum 0.6841501510293466 1.095875068503963 0.2731334510103722 1.0 0.7864738518469068 4 Q9GZP9,Q8NBM4 2 +Negative regulation of amyloid precursor protein catabolic process 0.5432032698156828 1.0957824309807096 0.2731739988540123 1.0 0.7864738518469068 9 O95197,O75298 2 +Amyloid precursor protein biosynthetic process 0.6278911116704788 1.0954804172660757 0.2733062201453435 1.0 0.7864738518469068 5 Q9NQX7 1 +Copi coated vesicle budding 0.6839043309631552 1.094895013780921 0.2735626337827859 1.0 0.7864738518469068 4 Q15363,Q92538,Q9BVK6 3 +Positive regulation of camp dependent protein kinase activity 0.8149224806201546 1.093948530449373 0.273977552445255 1.0 0.7864738518469068 2 Q9Y4G8 1 +Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway 0.8149224806201492 1.0939485304493524 0.2739775524452641 1.0 0.7864738518469068 2 P04899 1 +Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process 0.8149224806201492 1.0939485304493524 0.2739775524452641 1.0 0.7864738518469068 2 P04899 1 +Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway 0.8149224806201492 1.0939485304493524 0.2739775524452641 1.0 0.7864738518469068 2 P04899 1 +Keratan sulfate metabolic process 0.8290791599353939 1.0884124990259836 0.2764130457554241 1.0 0.7916924143397089 3 O43505,P16278 2 +Prostate gland growth 0.8281098546042025 1.084924060019526 0.2779552907202265 1.0 0.792166494893114 3 Q05086,P07602 2 +Mitochondrial fission 0.4881843411989243 1.0844272120367435 0.2781754237712945 1.0 0.792166494893114 13 O00203,O60313,Q9UDX5,Q9NUQ9 4 +Nucleoside triphosphate biosynthetic process 0.3950663032949194 1.0816606007236476 0.2794033661055779 1.0 0.7931689888116716 33 P00846,Q9UJZ1,P00403,O75964,O75746,Q9UJS0 6 +Alcohol catabolic process 0.5402429176813471 1.0808427671943357 0.279767060833616 1.0 0.7935851060253339 9 Q10713,Q8WTV0 2 +Positive regulation of erad pathway 0.8263915587039403 1.078742903363908 0.2807023541367051 1.0 0.7954474314837664 3 P46379 1 +Exonucleolytic catabolism of deadenylated mrna 0.5397525697368556 1.0783681342249496 0.2808695018365417 1.0 0.7954848154913848 9 Q9NQT5,Q96B26,Q969T7 3 +Acute inflammatory response 0.6797039877288388 1.0781568883987696 0.2809637476244142 1.0 0.7954848154913848 4 P42785,P02786 2 +Fucose metabolic process 0.6795241841546924 1.0774407387011475 0.281283412354977 1.0 0.7956869696361 4 Q9BTY2,P04066 2 +Synaptic vesicle membrane organization 0.5921586608739877 1.076200350702989 0.2818376629523129 1.0 0.7959368645055802 6 O43760 1 +Negative regulation of ubiquitin dependent protein catabolic process 0.4340156618393738 1.0759000284140197 0.2819719692288052 1.0 0.7959368645055802 23 Q8N163,Q9H2J4,Q96HY6,P46379,Q9UL15,O15294 6 +Regulation of mitochondrial gene expression 0.4744977398143 1.072583091124787 0.283458214678622 1.0 0.7967430296456461 14 Q567V2 1 +Positive regulation of neuron projection development 0.432834436907308 1.0671116585223095 0.2859214178591778 1.0 0.7980513986351206 23 Q14108 1 +Positive regulation of ion transmembrane transport 0.4293364068287359 1.065806773094497 0.2865109985252463 1.0 0.7980513986351206 24 P50570,Q4KMQ2,P08183,Q13586,P78417 5 +Regulation of mitochondrial fusion 0.6765533583952654 1.065612588257728 0.2865988063448432 1.0 0.7980513986351206 4 Q99536,Q9Y6C9 2 +Regulation of biomineralization 0.5894595884141733 1.0641167809022196 0.2872757998225776 1.0 0.7980513986351206 6 O75844,P20020 2 +Ceramide catabolic process 0.5892821285920999 1.063322422038115 0.2876357603158728 1.0 0.7980513986351206 6 P06865,P06280 2 +Positive regulation of monooxygenase activity 0.5892397294783172 1.0631326342398772 0.2877218069026153 1.0 0.7980513986351206 6 P16435,P00374,Q8WTV0 3 +Synaptic vesicle exocytosis 0.4600924905333923 1.0596693320497352 0.2892950595265151 1.0 0.7989927371843788 15 Q13277,P16615 2 +Respiratory gaseous exchange by respiratory system 0.5095173116433704 1.0588735579726598 0.2896573679965926 1.0 0.7989927371843788 11 O60476,Q7KZN9 2 +Energy derivation by oxidation of organic compounds 0.3749232761835337 1.0587770625422193 0.2897013222229718 1.0 0.7989927371843788 125 P00846,O95182,P31751,P00403,P03886,Q7KZN9,Q9UJS0,O43676,O14949,P14406,Q9UJZ1,O75964,P14635,Q9NQ88,Q13423,P13073,P22695,O95168,O75746,P20674,Q9UDW1,O96000,O43819,Q9BSK2,Q15070 25 +Positive regulation of cell cell adhesion 0.4166374048028179 1.0581229377357708 0.2899993982615294 1.0 0.7989927371843788 27 P30825,O75955,Q9HCL2,P49366,O00203,Q9NUQ9,P41440 7 +Regulation of fatty acid transport 0.6189266642902463 1.0572258562756651 0.2904085220445274 1.0 0.7991714692923101 5 P14174,P31751 2 +Positive regulation of calcium ion transmembrane transport 0.5091314765832281 1.056763054516991 0.2906197396282055 1.0 0.7991731149793211 11 P78417 1 +Endochondral bone morphogenesis 0.6186863068322995 1.0562010110413245 0.2908763889667742 1.0 0.7995358719026686 5 O75844 1 +Regulation of membrane permeability 0.4416026091311764 1.0550038376834487 0.2914235695802309 1.0 0.7997277519575647 19 P45880 1 +Negative regulation of fatty acid transport 0.8049095607234968 1.054956931114824 0.2914450227962102 1.0 0.7997277519575647 2 P31751 1 +Transepithelial transport 0.5873972484798166 1.054886163600334 0.2914773910775519 1.0 0.7997277519575647 6 P08183 1 +Cellular hyperosmotic response 0.5480326292101726 1.0538738144176216 0.2919406929824748 1.0 0.7998946339598226 8 O95202 1 +Reactive oxygen species metabolic process 0.4010937925170131 1.0537329094507442 0.2920052173893892 1.0 0.7998946339598226 42 P04899,P51790,P42785,P00403,Q9BSK2,Q9P0J0,Q13794,Q13423 8 +Ovarian follicle development 0.6732385261797037 1.0524253997417177 0.2926044203803308 1.0 0.8005097458975334 4 P35221,Q07812,Q05086 3 +Carbohydrate derivative catabolic process 0.3905488899128629 1.051691322435635 0.2929411935433319 1.0 0.8007475695576792 32 Q9NUJ1,P16278,P06280,Q13126,Q9BTY2,P54802,O60502,P49902 8 +Erad pathway 0.3979058412802707 1.0501123079632255 0.2936664806062738 1.0 0.8017044892190015 39 Q9UBV2,P46379,Q92575,P51572,Q8IXB1,Q96A33,Q8WU17 7 +Lung cell differentiation 0.6709760827407896 1.0434317279502558 0.2967483852868997 1.0 0.804657058447416 4 Q13155,P35222,P09960 3 +Regulation of transmembrane transport 0.4126982336125299 1.0415411143794484 0.2976244819116949 1.0 0.8047593865296865 66 O75844,O75298,Q16625,P31751,P0CG08,P21796,P08183,P27105,Q13586,P78417 10 +Aminoglycan biosynthetic process 0.5321745296866356 1.0401263207498783 0.2982812166533 1.0 0.8047593865296865 9 P06865,Q8NCH0,O43505,O94923 4 +Adenylate cyclase activating adrenergic receptor signaling pathway 0.8151857835218044 1.0385279919076145 0.299024310300259 1.0 0.8047593865296865 3 Q9Y4G8,P04899 2 +Adrenergic receptor signaling pathway 0.8151857835218044 1.0385279919076145 0.299024310300259 1.0 0.8047593865296865 3 Q9Y4G8,P04899 2 +Protein hexamerization 0.5836530934419893 1.038134186539 0.2992075874930262 1.0 0.8047593865296865 6 O95202,Q96TA2,Q96RR1 3 +Lipid droplet organization 0.5691500609095999 1.0367740882591103 0.2998411542361574 1.0 0.8047593865296865 7 Q96CS3,Q14534,Q9Y679 3 +Liposaccharide metabolic process 0.4403451074861426 1.033355059805274 0.3014377692611369 1.0 0.8057352257292112 18 P06280,P16278,Q8NBX0 3 +Negative regulation of membrane potential 0.8135702746365112 1.032744909441197 0.3017232909340404 1.0 0.8057352257292112 3 O75915,Q13794 2 +Regulation of amyloid precursor protein catabolic process 0.491174137456893 1.03205287782931 0.3020473470011224 1.0 0.8057352257292112 12 O95197,O75298 2 +Negative regulation of response to cytokine stimulus 0.6669751517536977 1.027541862544362 0.3041653838258993 1.0 0.8070719767947175 4 Q14166,O94813 2 +Respiratory electron transport chain 0.4082620369381493 1.0268931685703728 0.3044707714312522 1.0 0.807173309315053 57 O43676,P13073,O95182,O96000,O14949,O95168,P00403,P14635,O43819,P03886,P20674,Q9UDW1,Q7KZN9,Q9UJS0 14 +Regulation of mitochondrion organization 0.3971088025819883 1.025693355550633 0.3050361472791059 1.0 0.8076339132833824 41 Q07812,P02786,Q96A26,O43464,P21796,O14737,Q99536,O60313,Q9NUQ9,Q9NQ88,Q9Y6C9,Q13794 12 +Positive regulation of t cell mediated immunity 0.6108717721439966 1.0229102713734095 0.3063502726008162 1.0 0.8083469546530911 5 Q9NUQ9,O15400 2 +Eye photoreceptor cell differentiation 0.665702801718674 1.022492810987797 0.3065477134578722 1.0 0.8083469546530911 4 P54802,Q8NBN7 2 +Organic hydroxy compound transport 0.397929026621263 1.020847394011407 0.3073267460358839 1.0 0.8086881946182333 30 Q14728,Q8WTV0,Q9BZF3,O15118,P04114,P53985,Q9P260 7 +Cytokine production involved in immune response 0.5279610951503297 1.0188692468963505 0.3082650453929394 1.0 0.8093093618663343 9 P09601 1 +Protein mannosylation 0.8093699515347386 1.017727525714442 0.3088074623824881 1.0 0.8093093618663343 3 O43505,O60762 2 +Protein o linked mannosylation 0.8093699515347383 1.017727525714442 0.3088074623824881 1.0 0.8093093618663343 3 O43505,O60762 2 +Receptor localization to synapse 0.5402555733066954 1.0160975703534965 0.309582925943253 1.0 0.8093093618663343 8 Q13277 1 +Associative learning 0.513392141740721 1.0139041491841534 0.3106284913345716 1.0 0.8100827844802599 10 P50897 1 +Receptor mediated endocytosis 0.4007484701518002 1.0130880135572826 0.3110181230779081 1.0 0.8100827844802599 47 Q14108,P50897,P50570,O14976,Q5VW38,O75955,Q9Y5X1,Q13432,P41440 9 +Amyloid beta metabolic process 0.5011208966932403 1.0129495516577829 0.3110842582238589 1.0 0.8100827844802599 11 O95197,O75298 2 +Dendrite extension 0.6081365577168971 1.0112728784139178 0.3118858432030407 1.0 0.8105513517268734 5 Q96PU5 1 +Regulation of neurotransmitter levels 0.4105272065413494 1.009169517451585 0.3128933429265248 1.0 0.8105513517268734 27 P21964,P16615,P50897,Q13277,O75955,P41440 6 +Postsynaptic cytoskeleton organization 0.6608973530743452 1.0034427307100438 0.3156472957013285 1.0 0.8129469604124883 4 P07196 1 +Fatty acyl coa biosynthetic process 0.4745602780864213 1.0033392551182547 0.3156972020220148 1.0 0.8129469604124883 13 Q9UMR5,P50897 2 +Vasculogenesis 0.5107028411517756 0.9997897951555358 0.3174122453916759 1.0 0.8129469604124883 10 O95470,Q4VCS5 2 +Regulation of microtubule depolymerization 0.5610041590121176 0.9991885155002004 0.3177033781870402 1.0 0.8129469604124883 7 Q9UJX6,Q8WWK9,O15344,Q92974,Q9ULW0 5 +Glycoprotein biosynthetic process 0.4065360191859441 0.9985038324424368 0.3180351070141907 1.0 0.8129469604124883 60 O15294,Q8NCH0,O43505,O14734,Q9BT22,O15118,O60762,Q86SF2,Q9NQX7,O60476,O60502,Q86YN1,Q96IZ0,Q9BXS4,Q9BV10,Q9HC07,P83436,P46977,O94923 19 +Ribonucleoside monophosphate catabolic process 0.6595882633732477 0.9982587137837812 0.3181539221112452 1.0 0.8129469604124883 4 P49902 1 +Purine nucleoside monophosphate catabolic process 0.6595882633732477 0.9982587137837812 0.3181539221112452 1.0 0.8129469604124883 4 P49902 1 +Ear development 0.4331865001033844 0.996306481606624 0.3191012554822703 1.0 0.8139431148592728 19 P54802,P42892 2 +Cytoplasmic pattern recognition receptor signaling pathway 0.484436588999427 0.9935660614047824 0.3204341738755718 1.0 0.8153962106162824 12 Q96RT1,Q9NUD5,P35232,Q96J02,O43657 5 +Neuron maturation 0.6579197603561069 0.9916550456507716 0.3213658273879149 1.0 0.8164571594438236 4 O75503 1 +Sodium ion homeostasis 0.5730588140497123 0.9907892321451938 0.3217885082860094 1.0 0.8164571594438236 6 Q96PU5,P04899 2 +Bone growth 0.8017927194734961 0.9907089815121632 0.3218277041566804 1.0 0.8164571594438236 3 O75844 1 +Growth plate cartilage development 0.8017927194734961 0.9907089815121632 0.3218277041566804 1.0 0.8164571594438236 3 O75844 1 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.7877906976744227 0.988796917952347 0.3227625125011848 1.0 0.8180734302619987 2 P10321 1 +Mammary gland epithelium development 0.5341110856300624 0.9862726728548608 0.3239993258619054 1.0 0.8199114404953863 8 Q92766,Q9NQC3,P31751 3 +Regulation of calcium ion transport 0.3984448774313652 0.9835925327453138 0.3253158981334967 1.0 0.8219208155412465 29 P21796,Q13586,P78417 3 +Mitochondrial electron transport nadh to ubiquinone 0.4027982867809576 0.9816473695531022 0.3262736021914532 1.0 0.8228885887494525 28 O43676,O96000,O95182,O75306,O95168,Q16718,O75208,P03886,Q9Y375,O75380 10 +Positive regulation of carbohydrate metabolic process 0.5568831911663472 0.9801914805888504 0.3269916090704723 1.0 0.8231406036938874 7 Q13794,P31751 2 +Neural retina development 0.5568480859816143 0.9800297114323432 0.3270714527419418 1.0 0.8231406036938874 7 P54802,P20020,P23634 3 +Metal ion transport 0.3972951499268021 0.974828454403315 0.3296453601170064 1.0 0.8257699779949573 99 O15173,Q9NUT2,P16615,P02786,Q4KMQ2,P35670,P21796,Q6P4Q7,P27105,Q13586,O75027,P78417,Q8IYU8,P04899,Q9BXP2,Q9UJZ1,Q8TAD4,Q15907,P23634,Q04656,Q07812,P50570,P98194,Q9HD20,Q12955,Q96PU5,P20020,O75844,Q9Y6M7,O95202,Q9HC07 31 +Positive regulation of cholesterol storage 0.7967689822294209 0.9728507045202236 0.3306275080390599 1.0 0.8262465210644734 3 P04114,Q8WTV0 2 +Vacuolar transport 0.3882252434353568 0.9715971704670862 0.331250990749647 1.0 0.8265157067751021 38 Q14108,O14976,P07602,O15118,Q9UNK0 5 +Sensory perception of mechanical stimulus 0.4580639017978251 0.9711753311129748 0.331460976061964 1.0 0.8265913094041659 14 Q14108 1 +Phosphatidylinositol 3 kinase signaling 0.530718995711146 0.9698193796235656 0.3321365311986601 1.0 0.8265913094041659 8 Q10713,Q8NDZ4 2 +Generation of precursor metabolites and energy 0.3074956276080786 0.9687156322031728 0.3326870908507118 1.0 0.8265913094041659 184 P00846,O95182,P31751,P00403,P03886,Q7KZN9,Q9UJS0,O43676,O14949,P14406,Q9UJZ1,O75964,P14635,Q9BRR6,Q9NQ88,Q13423,P13073,P22695,O95168,P35914,O75746,P20674,Q9UDW1,O96000,P16435,P22830,P06576,O43819,Q9BSK2,Q9P0J0,Q15070 31 +Substrate dependent cell migration 0.5680836386894496 0.9685921576811882 0.3327487177405284 1.0 0.8265913094041659 6 P06576 1 +Nucleoside monophosphate catabolic process 0.5979254782435277 0.9679107509855044 0.3330889445691856 1.0 0.8265913094041659 5 P16260,P49902 2 +Adp transport 0.5979011881688252 0.9678077739238528 0.3331403806111561 1.0 0.8265913094041659 5 Q86VD7 1 +Negative regulation of lipid transport 0.7953331710243255 0.967755276865695 0.3331666043546299 1.0 0.8265913094041659 3 P31751 1 +Centriole assembly 0.5301648305866252 0.9671323456359932 0.3334778775627807 1.0 0.8265913094041659 8 P41208 1 +Maintenance of protein localization in organelle 0.4455367747834561 0.9663604596966412 0.3338638423476341 1.0 0.8269193313169763 15 P24390 1 +Development of primary female sexual characteristics 0.5170830045402169 0.964031914592522 0.3350299255538553 1.0 0.8282074133436995 9 P57740,O95470,Q05086,O94813 4 +Perk mediated unfolded protein response 0.6500831540243073 0.960697285526404 0.3367043964794129 1.0 0.8305443617100686 4 Q15363 1 +Integrated stress response signaling 0.6500831540243073 0.960697285526404 0.3367043964794129 1.0 0.8305443617100686 4 Q15363 1 +Mitochondrial fragmentation involved in apoptotic process 0.5648684801921791 0.9542628116728944 0.3399506272373265 1.0 0.8322318075846254 6 Q8N163,Q07812 2 +Regulation of protein targeting 0.414482017169853 0.9532920864698832 0.3404420999191266 1.0 0.8322318075846254 24 P27105,P55786,P31751 3 +Regulation of nitric oxide metabolic process 0.514927948904336 0.9531790073579568 0.3404993808241578 1.0 0.8322318075846254 9 P06280,Q08722,P50570 3 +Regulation of cellular carbohydrate catabolic process 0.5641498143780945 0.9510616506627544 0.3415730807284101 1.0 0.8322318075846254 6 Q14108 1 +Microtubule anchoring 0.5626691595099889 0.9444685305856988 0.3449302757903876 1.0 0.834655744740047 6 O75381 1 +Inositol lipid mediated signaling 0.4751956854513638 0.9408223581034728 0.3467959012261046 1.0 0.8355496961909148 12 Q10713,Q8NDZ4,Q05086,O15294 4 +Regulation of plasma lipoprotein particle levels 0.4280435544250933 0.9396221171778693 0.3474114272953299 1.0 0.8355496961909148 17 Q6PIU2,P09601,P04114,Q8WTV0 4 +Positive regulation of receptor catabolic process 0.7748708010335921 0.939359308084332 0.3475462978057384 1.0 0.8355496961909148 2 P18031 1 +Response to ischemia 0.5477623248796082 0.9382024310155834 0.3481403893080339 1.0 0.8355496961909148 7 O95831 1 +Regulation of heterotypic cell cell adhesion 0.7869268262497058 0.9380038783509131 0.3482424169994471 1.0 0.8355496961909148 3 P41440 1 +Regulation of toll like receptor 3 signaling pathway 0.7869268262497058 0.9380038783509131 0.3482424169994471 1.0 0.8355496961909148 3 P41440 1 +Forebrain neuron differentiation 0.6441330833087919 0.937262502388448 0.3486235462329357 1.0 0.8355496961909148 4 Q9Y4G8,O14949 2 +Forebrain neuron development 0.6441330833087919 0.937262502388448 0.3486235462329357 1.0 0.8355496961909148 4 Q9Y4G8,O14949 2 +Negative regulation of cellular protein catabolic process 0.3830482565202253 0.9370188345421772 0.3487488697265113 1.0 0.8355496961909148 31 Q8N163,Q96HY6,P46379,Q9UL15,Q9GZU8,Q92530 6 +Negative regulation of defense response to virus 0.5906069453153103 0.9369263977321552 0.3487964194075852 1.0 0.8355496961909148 5 O43657 1 +Regulation of endocytic recycling 0.7742248062015499 0.9368999601901586 0.3488100196897539 1.0 0.8355496961909148 2 Q9H4M9 1 +Protein localization to endoplasmic reticulum exit site 0.5902370904157528 0.9353629332673936 0.3496012925404108 1.0 0.8355496961909148 5 Q92538,Q5JRA6,P51572 3 +Cellular response to nutrient 0.5469252936863884 0.934353710426106 0.3501214671020058 1.0 0.8364256316444657 7 P09601 1 +Copper ion transmembrane transport 0.7729328165374701 0.931985043672298 0.3513442548847139 1.0 0.8367841270216639 2 P35670 1 +Copper ion import 0.7729328165374701 0.931985043672298 0.3513442548847139 1.0 0.8367841270216639 2 P35670 1 +Response to cobalt ion 0.772932816537458 0.9319850436722528 0.3513442548847372 1.0 0.8367841270216639 2 Q9NQ88 1 +Mitochondrial calcium ion homeostasis 0.4731975189038863 0.9294281164906872 0.3526672622598268 1.0 0.8367841270216639 12 Q8IYU8,P08133,O95202,P51572,Q9Y3D6 5 +Triglyceride catabolic process 0.7719638242894076 0.9283021979430908 0.3532508342777882 1.0 0.8367841270216639 2 P04114 1 +Vesicle fusion with golgi apparatus 0.6411796031576789 0.9256548133780922 0.3546253977793596 1.0 0.8373459453391756 4 Q9BSR8,O75396 2 +Collagen metabolic process 0.4965366375491548 0.9255261757031524 0.3546922744038636 1.0 0.8373459453391756 10 Q9UBG0,P08670,Q92791,Q32P28 4 +Carbohydrate derivative biosynthetic process 0.2955837665590902 0.9253363034522436 0.354791000433843 1.0 0.8373459453391756 164 P00846,Q9UMR5,P00403,O15294,Q8NCH0,O43505,O14734,Q9UJS0,Q53GQ0,P50897,Q9BT22,P06865,Q9UJZ1,Q06203,O75964,O15118,Q8TB61,O60762,P16260,Q86SF2,Q9NQX7,Q9NR45,O95563,O60476,O60502,O75746,Q86YN1,Q96IZ0,Q9BXS4,Q9BV10,Q9HC07,P06576,Q13126,P46977,Q8NBX0,O94923 36 +Adenylate cyclase modulating g protein coupled receptor signaling pathway 0.4614032286786366 0.9251021613859576 0.3549127688953502 1.0 0.8373459453391756 13 Q9Y4G8,P04899,P07602,Q14344,Q9NZJ7,Q9NPQ8 6 +Cellular modified amino acid catabolic process 0.5212757414611021 0.924074602565882 0.3554474753928076 1.0 0.8373459453391756 8 Q9UHG3 1 +Regulation of presynaptic cytosolic calcium ion concentration 0.7827205432921149 0.9231721822842442 0.3559174830152631 1.0 0.8379117257744156 3 P20020 1 +Alcohol biosynthetic process 0.3816309400935125 0.9214800078405336 0.3567998742643306 1.0 0.8381301121641421 37 P61457,P16435,P48449,P37268,Q15392,Q13510,Q15800,P04114,Q16850,O76062 10 +Cell migration involved in gastrulation 0.7818703667448385 0.9201790842161456 0.3574791824332961 1.0 0.8381301121641421 3 Q4VCS5 1 +Regulation of collateral sprouting 0.7697028423772656 0.9197202119200408 0.3577189876310842 1.0 0.8381301121641421 2 Q15375 1 +Collateral sprouting 0.7697028423772656 0.9197202119200408 0.3577189876310842 1.0 0.8381301121641421 2 Q15375 1 +Negative regulation of collateral sprouting 0.7697028423772656 0.9197202119200408 0.3577189876310842 1.0 0.8381301121641421 2 Q15375 1 +Response to mineralocorticoid 0.5569861503837945 0.9191922619109788 0.3579950178529332 1.0 0.8381301121641421 6 O95831,P07196 2 +Positive regulation of anion transport 0.5431918739777709 0.9171982933600712 0.3590387409660649 1.0 0.8387165924170831 7 P08183 1 +Regulation of electron transfer activity 0.6386921087190358 0.91589210908246 0.3597234859506715 1.0 0.839092993065431 4 Q04656,Q9BSH4 2 +Chondrocyte differentiation 0.5425509589834772 0.9142551477323864 0.3605827924977447 1.0 0.8403640627329508 7 P16435,Q9C0E8,P08133,Q92896 4 +Organelle fusion 0.3891096423902396 0.9130016174395446 0.3612416908714457 1.0 0.8403640627329508 46 O43752,Q9NX63,P02786,P31751,Q12981,O15400,Q9UJZ1,O75396,Q99536,Q9BSR8,Q07812,Q13277,O60313,O14653,Q9Y6C9,Q9Y3D6,O95249,O60499,Q9UNK0 19 +Positive regulation of mitochondrial calcium ion concentration 0.5551629860351804 0.9110940301277322 0.3622458316824655 1.0 0.8415694134754971 6 Q9Y3D6,P51572 2 +Aspartate transmembrane transport 0.5841147587378299 0.9095190336140284 0.3630762154599183 1.0 0.8422249322203681 5 Q8TDW0,O75746,Q9UJS0 3 +Negative regulation of cell growth 0.3938651202424508 0.908620141501687 0.3635506709940923 1.0 0.8426597442980827 28 Q8N163,P50897,Q9NQC3,O94813,Q9P0J0 5 +Lens fiber cell development 0.766149870801014 0.9062670358405608 0.3647945288038008 1.0 0.8426597442980827 2 P08670 1 +Lens fiber cell differentiation 0.766149870801014 0.9062670358405608 0.3647945288038008 1.0 0.8426597442980827 2 P08670 1 +Ensheathment of neurons 0.4201817714457604 0.9056619726991332 0.3651147959955791 1.0 0.8426597442980827 19 Q9NR77,P31751 2 +Positive regulation of neural precursor cell proliferation 0.5532099814066918 0.9024252674669136 0.3668310037158813 1.0 0.8426597442980827 6 P04899 1 +Signaling receptor ligand precursor processing 0.635093153179232 0.901790290417707 0.3671682785997729 1.0 0.8426597442980827 4 P42892 1 +Glycerolipid biosynthetic process 0.3899433549908284 0.8994698106321347 0.3684024691489789 1.0 0.8445850598157921 49 Q8TBX8,Q8WTV0,Q9NPH0,Q96N66,Q9Y6K0,Q9HCL2,Q8NCC3,O60762,Q10713,Q99943 10 +Skeletal muscle cell differentiation 0.5390583792624228 0.8982275495100497 0.3690642487978199 1.0 0.8447607416341131 7 Q9Y5Q8,P50402 2 +Endocytosis 0.3923767778545544 0.8972416191327597 0.369590001360232 1.0 0.8447607416341131 96 Q14108,P02786,Q5VW38,O75955,Q08380,O60749,P51790,P50897,Q8WTV0,Q9UBG0,Q9Y5X1,O15118,Q5JRA6,P50570,P61978,Q13432,Q96PU5,Q5KU26,O14976,Q05086,Q9NX40,Q8NC96,P41440 23 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.445977507010257 0.8967060913967861 0.3698757693564514 1.0 0.84479319003064 14 Q07812,Q96A26,O95831,Q9NZJ7,Q13794 5 +Regulation of ion transmembrane transport 0.3933656548727397 0.8955397892408649 0.370498605795277 1.0 0.8448570771122403 55 O75844,P50570,P23634,Q4KMQ2,P0CG08,P21796,Q96PU5,P08183,P27105,Q13586,O75915,P78417 12 +Urogenital system development 0.3807065729012436 0.8944022216870141 0.3711067242095838 1.0 0.8450569645035358 39 O75844,Q07812,P46379,O95470,P07602,Q05086,O94813,P57740,Q9NZJ7,Q15375,Q13418 11 +Ribonucleoside triphosphate metabolic process 0.3780671941894947 0.8893576986303474 0.3738108714521617 1.0 0.8463964695936754 37 P00846,Q9UJZ1,P00403,O75964,O75746,Q9UJS0 6 +Regulation of adenylate cyclase activity 0.6318719686694145 0.8891929496131137 0.3738993912785793 1.0 0.8463964695936754 4 Q13586 1 +Regulation of cyclase activity 0.6318719686694145 0.8891929496131137 0.3738993912785793 1.0 0.8463964695936754 4 Q13586 1 +Regulation of hormone biosynthetic process 0.7613049095607162 0.8879888629866859 0.3745467420559834 1.0 0.8463964695936754 2 P16435 1 +Regulation of steroid hormone biosynthetic process 0.7613049095607162 0.8879888629866859 0.3745467420559834 1.0 0.8463964695936754 2 P16435 1 +Positive regulation of canonical wnt signaling pathway 0.419156121920332 0.8879018918151547 0.3745935270192089 1.0 0.8463964695936754 18 Q8N163,O75787,Q9BZK7,Q96K76,Q13418 5 +Positive regulation of er associated ubiquitin dependent protein catabolic process 0.7606589147286729 0.8855578049035224 0.3758558575445585 1.0 0.8473975957590871 2 P51572 1 +U4 snrna 3 end processing 0.5360401753998988 0.8843924222282148 0.376484412176129 1.0 0.8476519431152045 7 Q5RKV6,Q9NQT5,Q96B26 3 +Lipophagy 0.6302097484561116 0.8827017251625177 0.3773974498041035 1.0 0.847976875924346 4 Q9Y679 1 +Positive regulation of protein tyrosine kinase activity 0.7690740848315127 0.8753328759139477 0.3813928109705955 1.0 0.8523270938658382 3 Q13432 1 +Vacuolar localization 0.4181687769782684 0.8668559257585808 0.3860209550049776 1.0 0.8543509455860887 16 Q9H267,Q6IAA8,P35579,P09601,O60271,P51809,Q96AX1,Q9BZG1,Q9UNH7 9 +Bleb assembly 0.7658256033520323 0.8640128605447381 0.3875808257922872 1.0 0.8556352953155276 3 Q9NR77 1 +Negative regulation of nuclear division 0.4167561773074582 0.8633803187871621 0.3879283967996709 1.0 0.8559796982739728 17 P50748,Q96DY7 2 +Maintenance of protein location in cell 0.4152997318436382 0.8614905145778231 0.3889679431496218 1.0 0.8573134721738286 18 P24390 1 +Lipopolysaccharide mediated signaling pathway 0.5309275393919948 0.8609930797751799 0.3892418544755851 1.0 0.8573134721738286 7 Q8WTV0 1 +Serine transport 0.7649088747502322 0.8608233581532168 0.3893353381432161 1.0 0.8573134721738286 3 Q96NB2 1 +Regulation of protein dephosphorylation 0.4162818765766644 0.8601818798360642 0.3896887915416169 1.0 0.8575026274568365 17 Q86XL3 1 +Defense response to gram positive bacterium 0.5722789579228288 0.8597780354115957 0.3899114091630706 1.0 0.8576980551596716 5 Q96EE3,P60602 2 +Prostanoid metabolic process 0.483788483336868 0.8589069339919085 0.390391863550533 1.0 0.8581220012632912 10 Q9H7Z7,Q8N4Q0 2 +Adipose tissue development 0.4722587492217954 0.855494212901705 0.3922776068261417 1.0 0.8587920243551014 11 O15173,P43490 2 +Selective autophagy 0.4010352358143362 0.851558863655894 0.3944589794617616 1.0 0.8605195715720273 24 Q96HY6,O43464,P21796,Q9Y679,Q9NQ88,O15269 6 +Positive regulation of metallopeptidase activity 0.7512919896640775 0.8504751823214931 0.3950609525943009 1.0 0.8605195715720273 2 Q96HY6 1 +Eating behavior 0.7512919896640723 0.8504751823214748 0.3950609525943112 1.0 0.8605195715720273 2 P50416 1 +Negative regulation of protein targeting to mitochondrion 0.7618739903069517 0.8502805204139153 0.3951691439691511 1.0 0.8605195715720273 3 O95817,O95429 2 +Roof of mouth development 0.5697492051362731 0.8491892643915899 0.3957759860329444 1.0 0.8605576901191226 5 O95470 1 +Negative regulation of mrna splicing via spliceosome 0.4271402571103319 0.8487068696487041 0.3960444226926669 1.0 0.860690505804357 15 P98175,P26368,O75494,O00422,Q16629,P61978 6 +Regulation of immune system process 0.2909176977321449 0.8405722676605222 0.4005876002528006 1.0 0.8657129842743926 164 P46379,Q96RT1,O96005,O75955,Q9HCL2,Q9NPR9,O15400,Q9NQC3,Q9UJZ1,Q08722,P28070,P49366,P12956,Q9BXW9,Q9NZ08,P09601,Q5KU26,O00203,Q9NUQ9,Q9NR50,P30825,O94813,P14174,O43657,P41440 25 +Magnesium ion homeostasis 0.7589660743134099 0.8402026540301416 0.400794770586153 1.0 0.8657129842743926 3 Q12955,Q6P4Q7 2 +Atp metabolic process 0.3708632518123149 0.8384258217520187 0.4017915922212645 1.0 0.8657129842743926 115 P00846,O95182,P00403,P03886,Q7KZN9,Q9UJS0,O43676,O14949,P14406,Q9UJZ1,O75964,P14635,Q9BRR6,Q9NQ88,P13073,P22695,O95168,O75746,P20674,Q9UDW1,O96000,Q9BSK2 22 +Regulation of oxidative phosphorylation 0.4780993315285195 0.8292736566775081 0.4069495739318025 1.0 0.8699192752997195 10 P14406 1 +Oligosaccharide lipid intermediate biosynthetic process 0.4894341091433299 0.825284859246833 0.409209885673218 1.0 0.872028494601857 9 Q9BV10,Q9BT22,Q9H553,Q86YN1 4 +T helper 17 type immune response 0.7445090439276457 0.8252776183877877 0.409213995594756 1.0 0.872028494601857 2 P40763 1 +Regulation of reactive oxygen species biosynthetic process 0.4892558506071379 0.8243949428201608 0.4097151874160225 1.0 0.8725163957929251 9 P51790,P00403,Q9BSK2 3 +Specification of symmetry 0.5354023420605748 0.823732866999364 0.4100913600098139 1.0 0.8727375888655071 6 Q15363 1 +Regulation of reactive oxygen species metabolic process 0.3746892506972367 0.8227380728678186 0.4106569594514466 1.0 0.8730716783030756 30 P04899,P51790,P42785,Q7Z4W1,P00403,Q9BTZ2,Q9BSK2,Q9NQ88,O75027,P60602 10 +Positive regulation of autophagy 0.3970724782189622 0.8216462652889603 0.4112782498360881 1.0 0.8738129205997098 24 P21796,P09601,Q8TBX8,Q9BXS4 4 +Negative regulation of protein catabolic process 0.3734463133873362 0.8195585223188802 0.4124678271046424 1.0 0.8742955386529693 40 Q8N163,Q96HY6,P46379,Q9UL15,O15294,Q9GZU8,P10619,Q92530,Q16850 9 +Respiratory system development 0.3965114025457941 0.8174146141641397 0.4136915268610672 1.0 0.8743724207893663 24 P46379 1 +Transferrin transport 0.6133243160074363 0.8171627465628416 0.4138354287601036 1.0 0.8743724207893663 4 P50570,P02786 2 +Positive regulation of wnt signaling pathway 0.3991491073557649 0.8166414961329173 0.4141333337779276 1.0 0.8743724207893663 23 Q8N163,Q9H2V7,O75787,Q9BZK7,Q96K76,Q13418 6 +Regulation of monooxygenase activity 0.4750315268314669 0.8133252347146133 0.4160316126524486 1.0 0.8752405135791025 10 P16435,Q8WTV0,P06280,P23634,P00374 5 +Lipid storage 0.4099476573145329 0.8122807168148268 0.4166305727682466 1.0 0.8752405135791025 16 Q9H6V9,Q8WTV0,Q9Y679,Q14534,P50416 5 +Protein processing 0.378916321191277 0.8117080574447402 0.4169591698329149 1.0 0.8752405135791025 47 O75844,Q96F07,Q92896,Q15392,Q9UJZ1,O75503,P42892,O75787,Q96TA2,P67812,Q10713,Q8WU17,O75976,Q9BXS4 14 +Mitochondrial genome maintenance 0.4860938868717595 0.8086225400997854 0.4187322955758494 1.0 0.876861814649198 9 Q9BQP7,Q9BSK2 2 +Learning 0.409184147668521 0.8072222044086509 0.4195384752233835 1.0 0.8778823568408729 16 Q05086,Q13641,P50897,O00264 4 +Motor learning 0.7390180878553004 0.8050161521041777 0.420810359066214 1.0 0.8780287007899984 2 Q05086 1 +Mechanoreceptor differentiation 0.4850152331850887 0.8032478802001435 0.4218314761374153 1.0 0.8789370707970636 9 P54802 1 +Glycolytic fermentation 0.7478296970624221 0.8018367917371771 0.4226473731708045 1.0 0.87960053961846 3 Q9NQ88 1 +Fermentation 0.7478296970624221 0.8018367917371771 0.4226473731708045 1.0 0.87960053961846 3 Q9NQ88 1 +Response to dsrna 0.4081588626321114 0.8004323797101204 0.4234603269971688 1.0 0.8801493826367874 16 Q5KU26,Q13794,P41440 3 +Iron ion transmembrane transport 0.747087791894472 0.7992944085844994 0.4241197202806077 1.0 0.8811036315091404 3 O75027 1 +Programmed necrotic cell death 0.4300811771275016 0.7991656726514184 0.42419435364075 1.0 0.8811036315091404 14 Q13510,O15294,P16989 3 +Neutral lipid metabolic process 0.4061103418070776 0.7987054319657516 0.4244612363359787 1.0 0.8813723760653139 18 Q9UBV2,Q8WTV0,Q9HCL2,Q9BZK7,Q8NCC3,P04114,P50416 7 +Postsynaptic signal transduction 0.6080859801916381 0.7969963281694152 0.425453163822264 1.0 0.8825743624921399 4 P04899 1 +Regulation of neurotransmitter uptake 0.6078726449230487 0.7961768657135794 0.4259292420180258 1.0 0.8827049600179585 4 P41440 1 +Cellular response to dsrna 0.4827738782910551 0.7920897976001089 0.42830831851616 1.0 0.8853454761975446 9 Q5KU26,P41440 2 +Positive regulation of protein serine threonine kinase activity 0.3981290691381981 0.7913515003867833 0.4287389033302591 1.0 0.8856643152906738 22 Q9Y4G8,Q8NDZ4,P14635,P14174,P23634 5 +Organelle membrane fusion 0.3660894400744684 0.7893201376204056 0.429924919709211 1.0 0.8875422658087093 31 O43752,O95249,O15400,Q13277,P31751,O60499,Q9UNK0,Q12981,O14653 9 +Regulation of clathrin dependent endocytosis 0.7439810930959468 0.7886675642659614 0.4303063303323253 1.0 0.8880436501707036 3 Q13432 1 +Regulation of phospholipid metabolic process 0.4480922467294155 0.786871537056053 0.4313570709691658 1.0 0.8893595643335543 12 Q8WTV0 1 +Cell volume homeostasis 0.5141587127664058 0.7846399308298743 0.4326647111685187 1.0 0.8900003522558554 7 Q4KMQ2,P51790,Q9BXP2 3 +Regulation of exit from mitosis 0.5264886718084338 0.7846322165389582 0.4326692354389572 1.0 0.8900003522558554 6 P50748 1 +Regulation of neuron projection development 0.3846290840603923 0.784544956592217 0.4327204134812965 1.0 0.8900003522558554 61 Q14108,Q9NQX7,O14976,Q9NQC3,P07196,Q9UL15,O94813,Q96PU5,P08670,Q9NR77,Q32P28,Q9UQB8,Q96G23 13 +Layer formation in cerebral cortex 0.6046694718084222 0.783890717339414 0.4331042370333455 1.0 0.8900003522558554 4 Q96N66 1 +Regulation of b cell proliferation 0.5251582697548846 0.778815943179438 0.4360881447013365 1.0 0.8930750822797339 6 P14174,Q96IZ0 2 +Electron transport chain 0.3864789119206179 0.7735348307214618 0.4392059235413303 1.0 0.895255404013306 72 O95182,O75306,P00403,P03886,Q7KZN9,Q9UJS0,O43676,O14949,O75208,O43175,P14635,P13073,O95168,O75746,P20674,Q9UDW1,O96000,P16435,O43819,P00390,Q9Y375,Q9P0J0,O75380 23 +Protein catabolic process 0.3257756394847746 0.7726955901329563 0.4397025571224597 1.0 0.8956127712599197 255 Q96HY6,P46379,Q9NUJ1,Q9UL15,O15294,Q9BZK7,P20618,Q96K76,Q16740,Q8N511,Q9UIQ6,P50897,Q8NHS3,Q9Y5X1,Q9GZU8,P28070,Q16850,Q14145,Q96A33,Q8WU17,Q8N163,Q8NBM8,O75503,P49721,P51572,Q96PU5,Q92530,O60502,O43791,Q13794,O75844,Q9UBV2,O00231,P28074,Q92575,Q9Y679,Q9UHG3,Q8IXB1,Q96TA2,Q9P0J0,O14773,Q9UJX3 42 +Negative regulation of oxidoreductase activity 0.6013621788583983 0.7712413559856188 0.4405638853357234 1.0 0.8957758753205691 4 P06280,Q15070 2 +Positive regulation of erk1 and erk2 cascade 0.435050703083331 0.769259817814868 0.4417390860980217 1.0 0.8957758753205691 13 P14174,Q13641 2 +Regulation of defense response to virus 0.4250593523692515 0.7685002594454446 0.44219003658664 1.0 0.8961608143395917 14 O75844 1 +Positive regulation of heart rate 0.7290051679586345 0.7684059357983437 0.4422460550023352 1.0 0.8961608143395917 2 P16615 1 +Negative regulation of transforming growth factor beta receptor signaling pathway 0.4888666813933177 0.7682337374975294 0.4423483333183258 1.0 0.8961608143395917 8 Q92896 1 +Positive regulation of deoxyribonuclease activity 0.7286821705426335 0.7672325669063464 0.4429432531853883 1.0 0.8967991954890521 2 P12004 1 +Nuclear envelope organization 0.368063449900299 0.7664617313620722 0.4434016138772798 1.0 0.8971604624221476 30 O75844,Q8N1F7,P50402,Q86XL3,P20700,O94901 6 +Regulation of tetrapyrrole metabolic process 0.7369124582227242 0.7646085133523707 0.4445046981814042 1.0 0.8981098189309976 3 Q9P0S9 1 +Positive regulation of synaptic transmission 0.4338348980818175 0.7621165809711952 0.4459904275609976 1.0 0.8981098189309976 13 Q13277,P41440 2 +Golgi to plasma membrane protein transport 0.4238935552143184 0.7613943456899045 0.4464215636989066 1.0 0.8981098189309976 14 Q4J6C6,Q12955,P98194,Q8N2H4 4 +Regulation of muscle organ development 0.4872327875062999 0.7604460461090242 0.4469880083232747 1.0 0.8981098189309976 8 P41440,P16989 2 +Sno s rna processing 0.4763777862161529 0.7603286554556667 0.447058157317999 1.0 0.8981098189309976 9 O95453,Q5RKV6,Q9NQT5 3 +Epithelial cell differentiation involved in prostate gland development 0.7355003834848532 0.7598230500896122 0.4473603628779414 1.0 0.8981098189309976 3 P07602 1 +Regulation of t cell mediated immunity 0.5203812678836374 0.7579776897916396 0.4484643389163918 1.0 0.8987299253240358 6 Q9NUQ9,O15400 2 +Negative regulation of gtpase activity 0.4863384980245344 0.756187151831499 0.4495369949053338 1.0 0.8990488687795619 8 Q4VCS5 1 +Protein localization to axon 0.7254521963824284 0.7555260929644156 0.4499333822658391 1.0 0.8990488687795619 2 Q12955 1 +Leukotriene biosynthetic process 0.7340872374798019 0.755041076461003 0.4502243361888571 1.0 0.8990488687795619 3 O14880,P09960 2 +Regulation of membrane repolarization 0.547001224755276 0.754805025973843 0.4503659777926947 1.0 0.8990488687795619 5 O75844 1 +Leukocyte apoptotic process 0.3949671150207718 0.7536832275163786 0.4510394555470567 1.0 0.8998328384863472 21 Q9HCL2 1 +L serine transport 0.7248062015503801 0.7531908094385582 0.4513352613239776 1.0 0.9001428204999056 2 Q15758 1 +Fatty acyl coa metabolic process 0.3992715208427158 0.752163900049112 0.4519525001380029 1.0 0.9003012172156898 18 Q9UMR5,P50897 2 +Pyramidal neuron differentiation 0.5960918288070419 0.7511635668641161 0.4525542235273663 1.0 0.900376165980856 4 O14949 1 +Reactive oxygen species biosynthetic process 0.452834319958139 0.7504215432849974 0.4530008599660591 1.0 0.900376165980856 11 P51790,P00403,Q9BSK2 3 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.7326435732342041 0.7501632822038683 0.453156370008235 1.0 0.900376165980856 3 O75844 1 +Positive regulation of i kappab kinase nf kappab signaling 0.3567165589396358 0.750057348482292 0.4532201659471504 1.0 0.900376165980856 32 Q9Y3E0,P98194,P09601,O43657 4 +Response to abiotic stimulus 0.3028415150913064 0.7466581234387083 0.4552699537199678 1.0 0.9029021825860988 201 P00846,P30519,Q96A26,P31751,P00403,O95831,Q96K76,Q9Y487,Q8N511,P12956,Q8N163,P09601,Q9BRK5,P55786,Q13432,P08183,Q9NR50,Q13794,O75844,O95202,P22830 21 +Bile acid biosynthetic process 0.48271415281745 0.7389539747362748 0.4599349456380053 1.0 0.9071658656010828 8 Q9BZF3 1 +Positive regulation of blood circulation 0.729240710823909 0.7386961870746813 0.4600915016147624 1.0 0.9071658656010828 3 P05023,P16615 2 +Actin myosin filament sliding 0.7292407108239058 0.7386961870746693 0.4600915016147697 1.0 0.9071658656010828 3 P14649,P60660 2 +Ether metabolic process 0.4603723810540858 0.737487844205434 0.460825732750791 1.0 0.907215278541944 10 P07099 1 +C4 dicarboxylate transport 0.4601915997813517 0.7365570113456128 0.4613917855365539 1.0 0.9074935088337868 10 Q9H936,Q15758,O75746,Q9UBX3,Q8TDW0,Q9UJS0 6 +Regulation of lipid transport 0.4090445236346039 0.7338004458585063 0.4630703687906095 1.0 0.908564757865873 15 Q9BZF3,P31751 2 +Regulation of tor signaling 0.4595841190941526 0.7334300113758537 0.4632962003902163 1.0 0.9087241252499602 10 O75844 1 +Membrane protein ectodomain proteolysis 0.5027470487549692 0.7331167785440924 0.4634872074701421 1.0 0.9087241252499602 7 Q9NZ08,Q9Y5X1 2 +Head morphogenesis 0.541677763418184 0.7329697265162256 0.4635768938482636 1.0 0.9087241252499602 5 O75787 1 +Cytoplasmic translational initiation 0.3969966553980951 0.7307245317687615 0.4649474282036592 1.0 0.9098616767525634 17 P55010 1 +Regulation of anion transport 0.4381018530370785 0.730623965709476 0.4650088694292351 1.0 0.9098616767525634 12 P14174,P08183 2 +Sequestering of calcium ion 0.4079671488508242 0.7269992593752014 0.4672264094465985 1.0 0.9103944855394778 15 O95202,P78417,P35670 3 +Lipid metabolic process 0.3346444978696686 0.7256891594773649 0.4680293489151408 1.0 0.9103944855394778 289 Q9H7Z7,O43681,Q9H6V9,Q9BWD1,O15254,Q9NPH0,P07602,Q9HCL2,P31751,Q9BZK7,Q9BZF3,O14734,Q9HB40,Q96G23,Q53GQ0,P07099,P50897,Q9BT22,Q8WTV0,P06865,P37268,Q15392,Q13510,Q9UJZ1,Q9Y6K0,Q8NCC3,O15118,Q9H6K4,Q16850,P53985,Q53H12,Q99943,Q9H3P7,P21964,P16278,Q6PIU2,P35914,Q15800,Q8N4Q0,P51648,Q86YN1,O76062,Q14534,P50416,O75844,Q8TBX8,P16435,Q9UBV2,Q13011,P38435,P14174,P06280,P23786,Q8NHP8,Q10713,Q8NBX0,O14773,Q06136,Q8IY17 59 +Columnar cuboidal epithelial cell differentiation 0.4798490274250856 0.7253630889918897 0.4682293110729905 1.0 0.9103944855394778 8 P07437,Q9NQ88 2 +Negative regulation of leukocyte chemotaxis 0.7244800376426981 0.7227271001777367 0.4698475625533878 1.0 0.9107114835098928 3 P14174 1 +Inorganic ion import across plasma membrane 0.5002080094853066 0.72171145756864 0.4704718963070129 1.0 0.9113704609634188 7 Q9BXP2,P05023,P23634 3 +Regulation of cellular response to growth factor stimulus 0.3533058874209288 0.7198282042613161 0.4716307771694603 1.0 0.9121311976354174 32 Q96F07,P50570,Q9Y2U8,Q92896,P35222,Q8N0X7,O94813,Q13573,Q06330,Q13526,O60315,P18031,Q13418,Q9UNH7,P23634 15 +Negative regulation of nitric oxide metabolic process 0.7232481010880896 0.7186090943978569 0.4723818083247675 1.0 0.9121311976354174 3 P06280 1 +Positive regulation of leukocyte proliferation 0.4260019381236141 0.716234865058803 0.4738463381914917 1.0 0.9121311976354174 13 P14174,P30825,Q9HCL2 3 +Negative regulation of autophagy 0.3877029228721445 0.715762245894516 0.4741381682355099 1.0 0.9121311976354174 22 P09601,Q9NRR5,P10619,O15118,Q9NQ88 5 +Er overload response 0.5867207298924814 0.7157233691693536 0.4741621779978242 1.0 0.9121311976354174 4 Q9UM00,Q96A33 2 +Regulation of cysteine type endopeptidase activity 0.3706447731996287 0.7138211648655807 0.4753377704678856 1.0 0.9129293133705368 50 P16435,Q07812,P78318,Q96F07,Q96A26,Q15392,Q9P0J0,O43464,P51572,O14737,O95831,Q96K76,Q9NZJ7,Q15375,Q13794,O75915,Q9Y3D6 17 +Signal peptide processing 0.5368969679427449 0.7134553186487878 0.4755640524538411 1.0 0.9129293133705368 5 O75503,P67812 2 +Positive regulation of calcium ion transport 0.405744874786311 0.7129881209265708 0.4758531079182906 1.0 0.9129657054044428 15 Q13586,P20020,P78417 3 +Membrane biogenesis 0.390808049286259 0.7120067168643719 0.4764606166841236 1.0 0.9134575431536238 20 Q86XL3,P41440,Q96CP7 3 +Allantoin metabolic process 0.7212321521014015 0.7118834081701276 0.4765369772707828 1.0 0.9134575431536238 3 P49902 1 +Neuron projection regeneration 0.5096139328425464 0.711297911769636 0.4768996453529932 1.0 0.9138794399738974 6 Q96G23 1 +Carbohydrate transmembrane transport 0.4330500773078789 0.7023313297883956 0.4824725593162466 1.0 0.9182799738938489 12 Q16625,P31751 2 +Regulation of neutrophil migration 0.4744902418653175 0.700026003180313 0.4839110654032761 1.0 0.9196856814763504 8 O94813 1 +Maintenance of location in cell 0.3576523132331626 0.6961439397740139 0.486338691414593 1.0 0.9207929882018074 38 P24390,P78417 2 +Negative regulation of neuron apoptotic process 0.3825168885937827 0.6939694138636726 0.4877013904556206 1.0 0.9207929882018074 23 P09601,P50897 2 +Embryonic hindlimb morphogenesis 0.7080103359173118 0.6932200518039797 0.4881714663062524 1.0 0.9207929882018074 2 Q15648 1 +Hindlimb morphogenesis 0.7080103359173118 0.6932200518039797 0.4881714663062524 1.0 0.9207929882018074 2 Q15648 1 +Regulation of neutrophil chemotaxis 0.4937425919004145 0.6927768118835932 0.488449626291394 1.0 0.9207929882018074 7 O94813 1 +Positive regulation of leukocyte cell cell adhesion 0.3864001113811609 0.692767016844917 0.4884557742382691 1.0 0.9207929882018074 21 P30825,Q08722,Q9HCL2,O00203,P49366,Q9NUQ9 6 +Regulation of myoblast fusion 0.5803064981064279 0.6916734195795392 0.4891424429772115 1.0 0.9207929882018074 4 O75955,P41440 2 +Regulation of syncytium formation by plasma membrane fusion 0.5803064981064279 0.6916734195795392 0.4891424429772115 1.0 0.9207929882018074 4 O75955,P41440 2 +Positive regulation of syncytium formation by plasma membrane fusion 0.5803064981064279 0.6916734195795392 0.4891424429772115 1.0 0.9207929882018074 4 O75955,P41440 2 +Positive regulation of myoblast fusion 0.5803064981064279 0.6916734195795392 0.4891424429772115 1.0 0.9207929882018074 4 O75955,P41440 2 +Positive regulation of map kinase activity 0.4930506024108898 0.6896896434762334 0.4903893800766852 1.0 0.9207929882018074 7 P14174,P30040,P18031 3 +Regulation of autophagy of mitochondrion 0.4214211372873263 0.689528644762312 0.4904906535625097 1.0 0.9207929882018074 13 P21796 1 +Glucose import 0.461702851921706 0.6879918457590484 0.4914579163566042 1.0 0.9207929882018074 9 Q16625,P31751 2 +Response to heat 0.3495678195789322 0.6867777183699078 0.4922228129060175 1.0 0.9207929882018074 32 P09601 1 +Protein o linked glycosylation 0.4013619404775454 0.6854284374632842 0.493073604291605 1.0 0.9207929882018074 15 O15294,O60502,O60762,O43505,Q86SF2 5 +Regulation of monocyte chemotaxis 0.5031425238713321 0.683459097274392 0.494316787859888 1.0 0.9207929882018074 6 O94813 1 +Cellular lipid metabolic process 0.3084259069819604 0.6802751368576815 0.4963302644497378 1.0 0.9207929882018074 223 Q9H7Z7,Q9BWD1,O15254,P48449,O95470,Q9NPH0,P07602,Q9HCL2,P31751,Q9BZK7,P04114,O14734,Q9HB40,O15269,Q96G23,Q53GQ0,P07099,P50897,Q9BT22,Q8WTV0,P06865,P37268,Q9UJZ1,Q13510,Q9Y6K0,Q8NCC3,O60762,Q53H12,Q99943,P61916,P16278,Q6PIU2,Q96N66,A1L0T0,Q15800,Q8N4Q0,P51648,Q86YN1,Q96BW9,P50416,O75844,Q8TBX8,P16435,Q9UBV2,Q13011,Q9C0I1,P14174,P06280,P23786,Q8NHP8,Q10713,Q8NBX0,Q9HBH5,Q06136,Q8IY17 55 +Activation of protein kinase c activity 0.7041343669250638 0.6795973779104385 0.4967594303979048 1.0 0.9207929882018074 2 P35232 1 +Activation of phospholipase c activity 0.7041343669250638 0.6795973779104385 0.4967594303979048 1.0 0.9207929882018074 2 P35232 1 +Branching involved in mammary gland duct morphogenesis 0.7041343669250638 0.6795973779104385 0.4967594303979048 1.0 0.9207929882018074 2 Q15648 1 +Regulation of phospholipase c activity 0.7041343669250638 0.6795973779104385 0.4967594303979048 1.0 0.9207929882018074 2 P35232 1 +Regulation of morphogenesis of an epithelium 0.7041343669250636 0.6795973779104371 0.4967594303979057 1.0 0.9207929882018074 2 P35222 1 +Regulation of t cell proliferation 0.3897774835424695 0.6794550655248909 0.4968495696070405 1.0 0.9207929882018074 16 P30825,P02786,Q9HCL2,P04439,P49366,Q96IZ0 6 +Nuclear transcribed mrna catabolic process deadenylation dependent decay 0.3778140542983997 0.6771370486920708 0.498319004297642 1.0 0.9212199147739564 24 O95453,P67809,O60506,Q96B26,Q9NQT5,Q969T7,Q9HBH5 7 +Cell cell adhesion mediated by cadherin 0.501059399448301 0.6745360047777822 0.4999706032136894 1.0 0.9225134043177172 6 P41440 1 +Tetrahydrobiopterin metabolic process 0.7096353695841784 0.673521926737096 0.5006153039568408 1.0 0.9226895783570348 3 P61457 1 +Regulation of golgi organization 0.5749849195107911 0.671858890424876 0.501673533666456 1.0 0.9229986655574002 4 Q9P2W9,P50570 2 +Intracellular sterol transport 0.4581547686267974 0.6706341682618854 0.5024536101361692 1.0 0.9232234913134628 9 O15118,Q9P260 2 +Epidermis morphogenesis 0.7082390953150255 0.6689424548900197 0.5035321867646549 1.0 0.9242959098400454 3 Q04656,O60568 2 +Negative regulation of fibroblast proliferation 0.4882771824761129 0.6684484439513266 0.5038473811357873 1.0 0.9246097088692804 7 Q71SY5,Q96IZ0,P50402 3 +Multicellular organism growth 0.3708302012047425 0.6668264781665317 0.5048829776033785 1.0 0.9250802935209466 26 Q15363,Q9BZK7,O75844,Q9HCL2 4 +Muscle cell proliferation 0.370754216633973 0.6662389772249385 0.505258363122751 1.0 0.9250802935209466 26 Q8NDZ4,P12956 2 +Regulation of b cell apoptotic process 0.5249897580443283 0.6652831419093822 0.5058694110312578 1.0 0.9251656421624754 5 P14174 1 +Regulation of carbohydrate catabolic process 0.3981440866317646 0.6652629788141702 0.5058823051138028 1.0 0.9251656421624754 15 Q9NQ88,Q14108,O75746 3 +Mammary gland development 0.3802065868577891 0.6617605611211621 0.5081246853928723 1.0 0.9267726973835296 22 Q92766,Q9NQC3,P00403,P31751,P35670,Q13505 6 +Histone h4 k16 acetylation 0.466106209930289 0.6606241848382652 0.5088533552214778 1.0 0.9267726973835296 8 O75844 1 +Response to carbohydrate 0.3513274887689763 0.6597320313113195 0.5094258074536162 1.0 0.9267726973835296 36 Q5KU26,Q9HCL2 2 +Glycoprotein metabolic process 0.3745103858375659 0.6582494266468749 0.5103778692391376 1.0 0.9267726973835296 70 O15294,Q8NCH0,O43505,O14734,Q9BT22,O15118,O60762,Q86SF2,Q8WU17,Q9NQX7,O60476,O60502,Q86YN1,Q96IZ0,Q9BXS4,Q9BV10,Q9HC07,P83436,P46977,O94923 20 +Nadph regeneration 0.4554921122222903 0.6576464554055437 0.5107653361272666 1.0 0.9267726973835296 9 Q13423 1 +Cellular carbohydrate catabolic process 0.3864290654672684 0.6576104270299373 0.5107884926824853 1.0 0.9267726973835296 16 Q14108,Q9NUJ1 2 +Regulation of superoxide metabolic process 0.5708768404315642 0.6566537003320301 0.5114036112978182 1.0 0.9267726973835296 4 P04899 1 +Regulation of morphogenesis of a branching structure 0.7043618739903081 0.6562724221047208 0.5116488583632026 1.0 0.9267726973835296 3 P35222,Q9NQC3 2 +Regulation of cell cycle checkpoint 0.4542753219221582 0.6517227232809552 0.5145800609541344 1.0 0.927993375920919 9 Q8N163 1 +Fatty acid derivative metabolic process 0.3785601894403563 0.6499481034622248 0.5157257444716481 1.0 0.927993375920919 22 Q53GQ0,P50897,Q9UMR5 3 +Pigment biosynthetic process 0.3764961397117438 0.6499240843087837 0.5157412601614368 1.0 0.927993375920919 23 Q9P0S9,P22830,Q06203,P50336,O75027,Q7KZN9,O00264 7 +Regulation of type i interferon mediated signaling pathway 0.4538685658789155 0.6497441432061368 0.5158575046983076 1.0 0.927993375920919 9 Q9NZI8,Q7Z434,Q14166,P61086,Q9Y3Z3,P18031,P08238,P55265 8 +Centriole centriole cohesion 0.7023407121920973 0.6496952319841219 0.5158891043996792 1.0 0.927993375920919 3 Q9C0F1 1 +Cellular response to mineralocorticoid stimulus 0.7022203347833655 0.6493041104339011 0.5161418294433968 1.0 0.927993375920919 3 O95831 1 +Positive regulation of cell junction assembly 0.4429123262102209 0.6482154010726985 0.5168456421012757 1.0 0.927993375920919 10 Q13641,P41440 2 +Positive regulation of secondary metabolite biosynthetic process 0.6944444444444464 0.6459264407305404 0.5183269950837766 1.0 0.9285679910416152 2 Q04656 1 +Positive regulation of developmental pigmentation 0.694444444444444 0.6459264407305314 0.5183269950837823 1.0 0.9285679910416152 2 Q07812 1 +Nuclear ncrna surveillance 0.4938940228367064 0.6439959413880484 0.5195780658327378 1.0 0.929089012443172 6 Q96B26,Q9NQT5 2 +Body morphogenesis 0.4826227986885025 0.6434174869529888 0.5199532395826807 1.0 0.929089012443172 7 O75787 1 +Membrane repolarization 0.462037526420042 0.6416193962244122 0.521120336023658 1.0 0.929089012443172 8 O75844 1 +Positive regulation of extrinsic apoptotic signaling pathway 0.441581481916166 0.6414698145406679 0.5212174865437826 1.0 0.929089012443172 10 Q9NQX7 1 +Regulation of receptor clustering 0.6928294573643408 0.6403703497131696 0.5219318544909592 1.0 0.9295868817135452 2 Q14696 1 +Positive regulation of catalytic activity 0.2855290857764799 0.6376869262200666 0.5236774976702856 1.0 0.9312877874226544 176 Q96HY6,Q96F07,Q96A26,P07602,P31751,O95831,Q9NZJ7,Q13586,O75915,Q9Y4G8,Q9BTE7,P04899,Q8WTV0,Q9Y5X1,O43464,Q14344,O14737,P14635,Q9BRX5,Q15375,P12956,Q9NQ88,P50991,P23634,Q07812,O95453,Q8NDZ4,Q9UL46,Q9BRT9,P51572,Q13432,P18031,Q16763,Q13794,P16435,Q99627,Q9P0J0,P14174,P40616 39 +Positive regulation of smooth muscle cell proliferation 0.4611789871926268 0.637619633200123 0.5237213121482722 1.0 0.9312877874226544 8 P09601 1 +Response to acetylcholine 0.6978716145008093 0.6352210512295192 0.5252842554818806 1.0 0.9323265721212276 3 P04899 1 +Regulation of protein localization to membrane 0.3517266241004229 0.633525697504967 0.5263904051224655 1.0 0.9331201595229546 39 O15400,Q9BXS4,Q13277,P98194,P31751,O14737,P27105,Q9UNK0,P23634,O00264 10 +Membrane fusion 0.3546331301476414 0.63170255818967 0.5275812561022122 1.0 0.933898399107728 42 O43752,O95249,O15400,Q13277,Q9P2W9,P31751,O60499,Q9UNK0,Q12981,O14653 10 +Retinal ganglion cell axon guidance 0.5638306047661101 0.630769016491062 0.5281915648341049 1.0 0.9342461177115376 4 O94813 1 +Cellular pigmentation 0.4196893097119377 0.6281091346253023 0.5299324494863902 1.0 0.935364178778896 12 Q13637,Q9H267,Q13561,P62820,O60315,O00203,Q15907 7 +Regulation of ras protein signal transduction 0.3685801907124689 0.6275631967775227 0.5302901244502143 1.0 0.9356343786748896 25 P50570,Q96RT1,O75955,O15294,Q96AG4,P41440 6 +Regulation of secondary metabolic process 0.6946688206785194 0.6249080257814712 0.532031424529616 1.0 0.936998780118094 3 Q04656,Q9Y4G8 2 +Muscle cell apoptotic process 0.4101765029222975 0.624448238045014 0.5323332540024004 1.0 0.936998780118094 13 Q8NDZ4,P09601 2 +Fat soluble vitamin metabolic process 0.4891406799988183 0.6238759341085038 0.5327090662555563 1.0 0.936998780118094 6 Q8N0U8,P38435 2 +Regulation of mitochondrial atp synthesis coupled electron transport 0.6940226171243961 0.6228334437503014 0.5333939785484316 1.0 0.936998780118094 3 Q9H3K2,P14635 2 +Glial cell migration 0.418701088980481 0.6226593598635652 0.5335083943730905 1.0 0.936998780118094 12 Q9NQC3,O94901,Q96N66,Q96G23 4 +Pyridine containing compound metabolic process 0.4777865371357082 0.62212950006125 0.5338567185798109 1.0 0.936998780118094 7 Q13126 1 +Transepithelial chloride transport 0.6873385012919888 0.6216039295189338 0.5342023365230211 1.0 0.936998780118094 2 P51798 1 +Cellular response to potassium ion 0.6873385012919886 0.6216039295189325 0.534202336523022 1.0 0.936998780118094 2 Q9NXV6 1 +Response to potassium ion 0.6873385012919886 0.6216039295189325 0.534202336523022 1.0 0.936998780118094 2 Q9NXV6 1 +Activation of immune response 0.3544083931447659 0.6208371623390926 0.5347067691858325 1.0 0.936998780118094 43 P12956,P46379 2 +Regulation of receptor mediated endocytosis 0.3760779955348499 0.6199518208872011 0.5352895069940622 1.0 0.937224906318794 21 P50897,P50570,O75955,Q13432,P41440 5 +Negative regulation of cell aging 0.5599958853809903 0.6167911893476227 0.537372464148778 1.0 0.938734749130836 4 P14174 1 +Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway 0.6914919991182351 0.6147294746517726 0.5387333912469836 1.0 0.9387560510642456 3 P04899 1 +Anaphase promoting complex dependent catabolic process 0.4361286499987653 0.6139325421853737 0.5392599049076228 1.0 0.9387560510642456 10 Q16763,Q9UJX3 2 +Dephosphorylation 0.3694267291536926 0.6134768641625036 0.5395610759590572 1.0 0.9387560510642456 68 P04899,Q9UNW1,Q6PIU2,Q9NPH0,Q86XL3,P11117,Q969T7,Q10713,P49902,Q8TF05,Q99956 11 +Schwann cell development 0.5119104880237351 0.6131730139900451 0.5397619463001391 1.0 0.9387560510642456 5 P31751 1 +Protoporphyrinogen ix metabolic process 0.5588897200349536 0.6127740207566289 0.5400257709914762 1.0 0.9387560510642456 4 P22830 1 +Leukocyte mediated cytotoxicity 0.4081443524933282 0.6127690865900338 0.5400290339944895 1.0 0.9387560510642456 13 P07437,Q9NUQ9,O15400 3 +Meiotic sister chromatid cohesion centromeric 0.6844315245478041 0.6117484909518113 0.5407041738770952 1.0 0.9387560510642456 2 O60566 1 +Lactation 0.4079573454005349 0.611695710374674 0.5407391005201354 1.0 0.9387560510642456 13 Q04656,Q13505,P00403,P35670 4 +Response to fibroblast growth factor 0.4860931435963722 0.6110389250347159 0.5411738112734468 1.0 0.9388157321414868 6 Q8NEM2,P35222,P48506,P46109,P46940 5 +Hindbrain development 0.3419851443274266 0.6090204012311017 0.5425109163679949 1.0 0.9392343162840036 33 Q5KU26,O95456,Q9BRK5,P54802 4 +Organic hydroxy compound biosynthetic process 0.3621334322113096 0.6085897154221723 0.5427964231220164 1.0 0.9392795914052412 54 P61457,P16435,O76062,P48449,P37268,Q14534,Q15392,Q13510,Q15800,Q9BZF3,P04114,Q16850,O14734 13 +Myoblast fusion 0.485179719510092 0.6072012521164929 0.5437173613986195 1.0 0.9394146324973452 6 O75955,P41440 2 +Syncytium formation 0.485179719510092 0.6072012521164929 0.5437173613986195 1.0 0.9394146324973452 6 O75955,P41440 2 +Positive regulation of torc1 signaling 0.6885298869143809 0.6052855665389825 0.5449892699610519 1.0 0.9408513925263514 3 Q96EE3,Q9P2J5 2 +P body assembly 0.4738840598751838 0.6050392761152171 0.5451529002081696 1.0 0.9408729600849814 7 P62310 1 +Positive regulation of axonogenesis 0.4340953010558656 0.6037078458477569 0.546037896922458 1.0 0.9409084607172398 10 P07196 1 +Regulation of calcium ion transmembrane transporter activity 0.4059399752927159 0.6001317998007862 0.5484184011008577 1.0 0.9429736779904438 13 P78417 1 +Negative regulation of growth 0.3396756303310817 0.5998324882212843 0.5486178792019061 1.0 0.9429736779904438 32 Q8N163,P50897,Q9NQC3,O94813,Q9P0J0 5 +Blood vessel endothelial cell migration 0.3745882091777547 0.5995581960143778 0.5488007144347635 1.0 0.9429736779904438 20 P42785,P09601,Q8WTV0 3 +Positive regulation of protein phosphorylation 0.3694551677745888 0.5994593910810222 0.5488665823061383 1.0 0.9429736779904438 82 Q9Y4G8,P41440,Q96HY6,P02786,Q99627,Q8NDZ4,P14174,O75955,Q9Y5X1,P31751,Q13432,P14635,O95429,Q15375,Q9H7B4,P12956,Q13418,P23634 18 +Positive regulation of t cell proliferation 0.4433150542645181 0.5987171303719119 0.5493615318382346 1.0 0.943571119797182 9 P30825,Q9HCL2 2 +Regulation of interleukin 1 mediated signaling pathway 0.6799095607235168 0.5965310320497277 0.5508205294242554 1.0 0.9455703250159286 2 Q86Y07 1 +Interleukin 1 mediated signaling pathway 0.6799095607235168 0.5965310320497277 0.5508205294242554 1.0 0.9455703250159286 2 Q86Y07 1 +Nucleoside triphosphate metabolic process 0.3525947887866638 0.5958735327584676 0.5512597157437829 1.0 0.945572395089644 44 P00846,Q9UJZ1,P00403,Q9H773,O75964,O75746,Q9UJS0 7 +Leukocyte homeostasis 0.4051668535557711 0.5957077120943604 0.5513705052744626 1.0 0.945572395089644 13 Q13794,Q9HCL2 2 +Positive regulation of cell killing 0.482409461552893 0.5955910141054377 0.5514484811016942 1.0 0.945572395089644 6 Q9NUQ9,O15400 2 +Golgi vesicle budding 0.5064751828160104 0.5917968907484653 0.5539866055169456 1.0 0.9468205497068224 5 Q15363,Q92538,Q9BVK6 3 +Proton transporting two sector atpase complex assembly 0.4707330694628804 0.5913003902532465 0.5543191681540234 1.0 0.9468205497068224 7 Q8N511 1 +Positive regulation of phospholipase activity 0.5060715703757276 0.5902165705082659 0.5550454641979241 1.0 0.9468205497068224 5 P35232,Q14344,P40616 3 +Crd mediated mrna stabilization 0.4508002591747259 0.5895804485747553 0.5554719626659266 1.0 0.9468205497068224 8 Q9NZI8,O60506,P11940,P67809 4 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.4508002591747259 0.5895804485747553 0.5554719626659266 1.0 0.9468205497068224 8 Q9NZI8,O60506,P11940,P67809 4 +Regulation of t cell activation 0.3397568651430609 0.5894965539660602 0.555528223137082 1.0 0.9468205497068224 33 P30825,O96005,Q08722,Q9HCL2,P49366,O00203,Q9NUQ9,Q96IZ0,Q9BXW9 9 +B cell proliferation 0.4409010319535724 0.5871350203865421 0.5571130291214803 1.0 0.9468205497068224 9 P14174,Q96IZ0,P02786 3 +Regulation of camp dependent protein kinase activity 0.5517198120499985 0.586903768265219 0.5572683388405706 1.0 0.9468205497068224 4 Q9Y4G8 1 +Positive regulation of nucleobase containing compound transport 0.5517129928894651 0.5868793059415852 0.5572847690541647 1.0 0.9468205497068224 4 Q07666,Q16630,P52298 3 +Positive regulation of rna export from nucleus 0.5517129928894651 0.5868793059415852 0.5572847690541647 1.0 0.9468205497068224 4 Q07666,Q16630,P52298 3 +Negative regulation of hormone secretion 0.4802672044583264 0.5866431586902188 0.5574433903907376 1.0 0.9468205497068224 6 Q6WKZ4,Q16836,Q8N183,Q8N5M9 4 +Positive regulation of ion transport 0.3429936525486496 0.5860243475830264 0.5578591532591826 1.0 0.9468205497068224 36 P50570,Q4KMQ2,P08183,P20020,P14174,Q13586,P78417 7 +Vesicle mediated transport in synapse 0.3423889982624509 0.585120448452964 0.5584667302376429 1.0 0.9468205497068224 31 P51790,P16615,P50570,O14976,Q13277,O00203 6 +Protein localization to cilium 0.440363316309395 0.5845600380242738 0.5588435846758535 1.0 0.9468205497068224 9 Q10713,Q9Y5K8,Q9H4M9 3 +Lipoprotein metabolic process 0.3691970825980598 0.5831614913456773 0.559784591872166 1.0 0.9468205497068224 22 P50897,Q9NUJ1,Q92643,O60762,P04114 5 +Antigen receptor mediated signaling pathway 0.3741170138776215 0.5831427593602226 0.5597972008358121 1.0 0.9468205497068224 18 Q9NR50,Q96IZ0,Q07812,Q9UJZ1 4 +Dna deamination 0.6810985460420176 0.5817979701545509 0.5607027714790491 1.0 0.9468205497068224 3 Q5RKV6,Q9NQT5 2 +Biological process involved in interaction with host 0.3560902389807237 0.5800656189350007 0.5618703678615851 1.0 0.9468205497068224 50 Q14108,O15118,Q8WTV0 3 +Hyperosmotic response 0.4293344567638065 0.5798679999165033 0.5620036367659509 1.0 0.9468205497068224 10 O95202 1 +Regulation of cell projection size 0.6803735717954665 0.5795227552126764 0.5622364970724241 1.0 0.9468205497068224 3 P07196 1 +Positive regulation of kinase activity 0.3589355076418493 0.5789908327560745 0.5625953587960326 1.0 0.9468205497068224 54 Q9Y4G8,Q99627,Q8NDZ4,P14174,Q9Y5X1,Q13432,P14635,Q15375,P12956,Q9NQ88,P23634 11 +Heart valve development 0.5494939341049365 0.5789336943482135 0.5626339138243805 1.0 0.9468205497068224 4 P43243,O94813 2 +Regulation of cation channel activity 0.3927486313864812 0.5741217651454695 0.5658854058539933 1.0 0.9468205497068224 14 P27105,P78417 2 +Positive regulation of adaptive immune response 0.4012689539172268 0.5734693284397154 0.5663269606398031 1.0 0.9468205497068224 13 O15400,P02786,Q5RKV6,Q9NUQ9,Q9NQT5 5 +Negative regulation of cellular response to growth factor stimulus 0.4276625371301996 0.5715307727881278 0.5676399067804603 1.0 0.9468205497068224 10 O14936,Q9Y2U8,Q8N0X7,O94813,P18031,P23634 6 +Regulation of systemic arterial blood pressure by hormone 0.6771451355540339 0.5694266535739193 0.5690666330472478 1.0 0.9468205497068224 3 P42892 1 +Endoplasmic reticulum to cytosol transport 0.39181693312494 0.568618212642204 0.5696152623449116 1.0 0.9468205497068224 14 Q9UBV2,Q96CS3,Q9GZP9,P51572,Q9Y679 5 +Regulation of apoptotic dna fragmentation 0.6766274907477462 0.5678133542969421 0.5701617109907988 1.0 0.9468205497068224 3 O95831 1 +Regulation of dna catabolic process 0.6766274907477462 0.5678133542969421 0.5701617109907988 1.0 0.9468205497068224 3 O95831 1 +Ventricular system development 0.4756574141118099 0.5674824506442617 0.5703864464170905 1.0 0.9468205497068224 6 Q9H6E4,Q96N66 2 +Negative regulation of intrinsic apoptotic signaling pathway 0.3384604485187802 0.5673129190494811 0.570501601283804 1.0 0.9468205497068224 34 Q8N163,Q9UL15,P45880,Q96K76,Q9P0J0,P14174 6 +Wnt signaling pathway involved in heart development 0.6705426356589159 0.5654655675410036 0.571757138020281 1.0 0.9468205497068224 2 P35222 1 +Cell proliferation involved in heart morphogenesis 0.6705426356589159 0.5654655675410036 0.571757138020281 1.0 0.9468205497068224 2 P35222 1 +Specification of animal organ identity 0.6705426356589159 0.5654655675410036 0.571757138020281 1.0 0.9468205497068224 2 P35222 1 +Ventricular trabecula myocardium morphogenesis 0.6705426356589159 0.5654655675410036 0.571757138020281 1.0 0.9468205497068224 2 Q15648 1 +Canonical wnt signaling pathway involved in heart development 0.6705426356589159 0.5654655675410036 0.571757138020281 1.0 0.9468205497068224 2 P35222 1 +Heart trabecula morphogenesis 0.6705426356589159 0.5654655675410036 0.571757138020281 1.0 0.9468205497068224 2 Q15648 1 +Cell surface receptor signaling pathway involved in heart development 0.6705426356589159 0.5654655675410036 0.571757138020281 1.0 0.9468205497068224 2 P35222 1 +Regulation of cardiac muscle cell proliferation 0.6705426356589153 0.5654655675410026 0.5717571380202817 1.0 0.9468205497068224 2 P06493 1 +Positive regulation of cardiac muscle cell proliferation 0.6705426356589153 0.5654655675410026 0.5717571380202817 1.0 0.9468205497068224 2 P06493 1 +Toll like receptor 4 signaling pathway 0.5456908923873307 0.5653863720715911 0.5718109919015362 1.0 0.9468205497068224 4 P41440 1 +Regulation of toll like receptor 4 signaling pathway 0.5456908923873307 0.5653863720715911 0.5718109919015362 1.0 0.9468205497068224 4 P41440 1 +Definitive hemopoiesis 0.6702196382428952 0.5644056933587103 0.5724780650797077 1.0 0.946886021615794 2 Q96JB5 1 +Pre mirna processing 0.6702196382428947 0.5644056933587083 0.572478065079709 1.0 0.946886021615794 2 O75569 1 +Mirna loading onto risc involved in gene silencing by mirna 0.6702196382428947 0.5644056933587083 0.572478065079709 1.0 0.946886021615794 2 O75569 1 +Regulation of cell aging 0.4080025175765205 0.5640757166332487 0.5727026035339153 1.0 0.946886021615794 12 O75844,P14174,Q96IZ0 3 +Regulation of nervous system process 0.4451679886511905 0.5637749505534275 0.5729073015033728 1.0 0.946886021615794 8 Q9UQB8 1 +Establishment of pigment granule localization 0.6752827140549329 0.5636293953256898 0.5730063771993237 1.0 0.946886021615794 3 Q15907,Q13561 2 +Positive regulation of ligase activity 0.6695736434108552 0.5622882686981658 0.5739196298602876 1.0 0.9479064229333788 2 Q13155 1 +Calcium ion transport into cytosol 0.3906047239510763 0.5614684166809885 0.5744782551072336 1.0 0.9481772530680652 14 P78417 1 +Gdp metabolic process 0.6686046511627839 0.5591179663763151 0.576081213933701 1.0 0.948787405271075 2 Q00013 1 +Negative regulation of response to external stimulus 0.3421157524941859 0.5580736125760084 0.5767941185177854 1.0 0.9491867237908675 38 P80303,P28070,Q9UMX5,P14174,O43657,Q96G23 6 +Glycolipid catabolic process 0.4733420637098584 0.557908712892184 0.5769067215776431 1.0 0.9491867237908675 6 P06280 1 +Negative regulation of insulin secretion involved in cellular response to glucose stimulus 0.6676356589147301 0.5559547063543264 0.5782418186098586 1.0 0.9494472359041312 2 Q8N183 1 +Cellular sodium ion homeostasis 0.4968056198085042 0.5542183700630988 0.5794294077762725 1.0 0.9494472359041312 5 Q96PU5,P05023 2 +Regulation of pigmentation 0.6717285945072642 0.5526222161017976 0.5805221261633737 1.0 0.949987418023714 3 Q07812,O60315 2 +Schwann cell differentiation 0.4712886488878355 0.549447106289015 0.5826986542237882 1.0 0.9506486061528334 6 P31751 1 +Protein localization to condensed chromosome 0.4146988941791436 0.5487763159210611 0.5831589657399954 1.0 0.9507126322672432 11 Q96DY7 1 +Calcium mediated signaling using intracellular calcium source 0.6703294159511449 0.5483093848497933 0.5834794844523143 1.0 0.9507126322672432 3 P51572 1 +Positive regulation of cytoplasmic translation 0.4143695778598892 0.5470741192124159 0.584327811976143 1.0 0.9518529287845175 11 P67809,P16989 2 +Positive regulation of osteoblast differentiation 0.5400968940968317 0.5456256028216536 0.5853233214434237 1.0 0.9525063443646472 4 P35222,Q13418 2 +Odontogenesis of dentin containing tooth 0.4320365741752429 0.5449268101829278 0.5858038562223109 1.0 0.9525380754554176 9 Q07812,P35221,P35613,Q6P4Q7,Q13586 5 +Exit from mitosis 0.4138992913417912 0.5446447078862237 0.5859978997770499 1.0 0.9525380754554176 11 P50748,Q16763 2 +Positive regulation of interferon gamma production 0.4940557002844756 0.5436436989364066 0.5866866825076393 1.0 0.9525380754554176 5 P04439,Q9NUQ9 2 +Regulation of steroid metabolic process 0.3784382460084168 0.543348208880332 0.5868900775081927 1.0 0.9525380754554176 15 P16435,P49748,Q6IAA8,Q13510,P04114,Q15637 6 +Negative regulation of protein maturation 0.4938974052933045 0.5430365648837367 0.5871046271538121 1.0 0.9525380754554176 5 Q92896 1 +Granulocyte differentiation 0.4595086997997331 0.5428367557322761 0.587242203802377 1.0 0.9525380754554176 7 O00203 1 +T cell activation 0.3533982647641883 0.5413383158522148 0.5882744153354387 1.0 0.9531722544281092 52 P24390,P30825,O96005,Q9UJZ1,Q9HCL2,P0CG08,Q08722,P49366,O00203,Q9NUQ9,Q96IZ0,Q9BXW9 12 +Apoptotic mitochondrial changes 0.3327355799146317 0.5394123146027741 0.5896023857324142 1.0 0.9531722544281092 32 Q8N163,Q96A26,P45880,O14737 4 +Regulation of histamine secretion by mast cell 0.6624677002583996 0.5392048178668581 0.5897455363563711 1.0 0.9531722544281092 2 Q9UNH7 1 +Nuclear transcribed mrna poly a tail shortening 0.4918837748824695 0.5353286437244282 0.5924226227951273 1.0 0.955087779707436 5 O95453 1 +Synaptic transmission dopaminergic 0.4917773761663799 0.5349221570836188 0.5927036861510602 1.0 0.9553006357124204 5 P41440 1 +Protein deneddylation 0.4387437162352295 0.5345938369504663 0.5929307462497915 1.0 0.9554263658776176 8 Q9BT78 1 +Negative regulation of neuron death 0.3356639657381824 0.5322545555016229 0.5945497024273534 1.0 0.9565922672086684 35 Q9UMX5,P07196,P09601,P50897 4 +Negative regulation of mitochondrion organization 0.393700801161595 0.5306359090245548 0.5956711068444398 1.0 0.9569877797449192 13 P02786,P42765,Q99536,O60313,Q9NQ88 5 +Membrane depolarization during action potential 0.6595607235142135 0.5298742271662962 0.5961991364593704 1.0 0.9569877797449192 2 Q12955 1 +Negative regulation of dendrite morphogenesis 0.6595607235141988 0.5298742271662494 0.5961991364594028 1.0 0.9569877797449192 2 Q9Y4G8 1 +Phagosome maturation 0.4900859051278902 0.5284708914044087 0.5971725452790908 1.0 0.9570180350959718 5 Q13637 1 +Meiosis i cell cycle process 0.3627878156418098 0.5274649382186145 0.5978707583895382 1.0 0.9573698629220436 21 Q92791,P46379,Q9BTX1,Q9BXW9 4 +Regulation of the force of heart contraction 0.489669941964196 0.5268875591057551 0.5982716737487932 1.0 0.9576882217853808 5 P16615,P10253,P23634 3 +Positive regulation of endocytosis 0.3653804922516718 0.5255883896886169 0.5991742253126309 1.0 0.9578921585381668 18 P50897,P50570,O75955,P61978,Q96PU5,P41440 6 +Transmembrane receptor protein serine threonine kinase signaling pathway 0.3404248257746372 0.5237481154091602 0.6004537450251313 1.0 0.9588425510714568 40 Q8N1F7,Q9UIQ6,Q92896,Q6PIU2,P08670,O00400 6 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.4274934944028362 0.5235074787648867 0.6006211479627366 1.0 0.9588425510714568 9 P35232,O43657,Q9NUD5 3 +Interferon gamma production 0.436229843605008 0.5232536308386456 0.6007977644096942 1.0 0.9588425510714568 8 Q9NUQ9,Q08722 2 +Collagen fibril organization 0.4358848319605224 0.5217008658076788 0.6018786217603878 1.0 0.9588425510714568 8 Q04656,Q92791,O75718 3 +Anterograde dendritic transport 0.6607431340872398 0.5190819165661349 0.6037036181768214 1.0 0.959725191312602 3 Q14254,Q9NUL3 2 +Negative regulation of type i interferon mediated signaling pathway 0.6595051615057692 0.5153495013689551 0.6063088136431207 1.0 0.961560160529298 3 Q14166 1 +Nitrogen compound transport 0.3590251965260322 0.5135994630637593 0.6075320550587346 1.0 0.961560160529298 562 O43615,Q9Y2D4,Q14108,P46379,P02786,Q99595,O14678,O60830,Q9NRW7,Q5VZ89,P57740,Q9NZJ7,Q9Y584,Q16836,O43808,O14925,P49458,P24390,P50897,Q5W0Z9,O75396,Q9NS69,O43464,Q15005,Q16850,O43731,P52292,P62072,O43772,O95817,Q8N4H5,Q07812,P98194,Q9HD20,P55786,P08183,O95429,P18031,Q9Y3D6,Q9Y282,P43307,Q9BY77,Q6P4A7,Q9P2W9,O60831,Q13190,Q08J23,L0R6Q1,Q9NV70,Q9BSK2,Q9P0J0,Q9H4M9,Q86V81,P41440,P61019,Q03518,A6NIH7,O15173,O43681,O43823,Q9H936,Q96CS3,Q96NB2,P53367,P07602,P31751,P0CG08,P49321,O95831,Q96P70,Q969Q5,P27105,Q6WKZ4,Q99567,P51991,Q5BJH7,Q9BTX1,O14737,O60725,P53985,Q96H78,Q53H12,Q7Z4Q2,Q13277,P41208,Q13432,Q9Y3B3,O14653,Q9UBV2,P30825,O75298,Q9Y5M8,Q8NC96,O60499,Q10713,Q9UNK0,Q15070,Q9Y3E0,O43752,Q9BRK0,Q96RT1,Q8N2H4,Q96PC5,O15127,Q9UJS0,Q15363,Q86VD7,Q9UGP8,Q9Y5X1,Q15388,Q8TB61,Q9Y619,Q96EE3,O75381,P50402,P51572,O00203,O75746,Q15629,Q9Y277,P50416,O95249,O95070,Q9UI26,Q9H2D1,Q16629,Q9Y679,Q96KC8,Q6NUQ1,O75955,O00400,P04114,P33527,O75915,O75027,O60749,Q9UP83,O15400,Q15758,Q08722,Q32P28,Q8N1F7,Q5JRA6,P50570,Q4J6C6,O95563,P60602,Q9BVK6,P83436,P67809,P10619,Q8TDW0,Q7Z3B4,P40616 154 +Fibroblast growth factor receptor signaling pathway 0.4859359844810871 0.512731320078918 0.6081392778101926 1.0 0.961562104283013 5 P46109,P35222,Q8NEM2,P46940 4 +Neuron differentiation 0.2868127353678834 0.5114704249630048 0.6090216924898373 1.0 0.9624825071153492 194 Q14108,Q96F07,Q8WUJ1,Q9UL15,P07196,O75955,Q9NZJ7,Q13641,Q96G23,O00264,Q9Y4G8,P50897,O14949,Q8NHS3,Q9NQC3,O43464,Q9BVA1,Q32P28,Q15375,Q9NQX7,P50570,Q13277,O75503,Q96PU5,P08670,P42892,Q9UQB8,Q9UBB6,Q9Y6M7,Q9UBB4,O14976,Q05086,O94813,Q9NR77,P54802,Q9Y4F1,P41440 37 +Regulation of aerobic respiration 0.3727190268976036 0.5085897900766588 0.6110397869966548 1.0 0.9630830915950124 15 P14406 1 +Response to ketone 0.3327253085807558 0.5067086088261924 0.6123592892534433 1.0 0.9631668495340572 35 P16435,P16278,P07196,O94813,Q13126,O95831,P20020,Q969T9,Q9H7B4 9 +Heart formation 0.6565428109854586 0.5064584030132654 0.6125348840506442 1.0 0.9631668495340572 3 P35222,Q06330 2 +Endothelial cell fate commitment 0.6518087855297164 0.5053248206020641 0.6133307124774885 1.0 0.9632333350898684 2 Q06330 1 +Epithelial cell fate commitment 0.6518087855297164 0.5053248206020641 0.6133307124774885 1.0 0.9632333350898684 2 Q06330 1 +Regulation of protein localization to plasma membrane 0.3522002393179126 0.5052207211694063 0.6134038180712704 1.0 0.9632333350898684 25 O15400,Q13277,P98194,O00264,Q9UNK0,Q9BXS4 6 +Cellular response to ionizing radiation 0.3614523511450241 0.5040153240420491 0.6142506085418618 1.0 0.9638546880669115 19 P12956 1 +Negative regulation of telomere capping 0.5271493212669698 0.5007006898408878 0.616581786712755 1.0 0.9651500006907836 4 P18887,Q92878,Q15554 3 +Rrna 3 end processing 0.4494980187881278 0.500312830434006 0.6168548211837912 1.0 0.9652662644770992 7 Q96B26,Q9NQT5 2 +Positive regulation of peptidyl serine phosphorylation 0.3800433807706305 0.4997338817943892 0.6172624719027868 1.0 0.9652726140270464 14 Q9H7B4,P14174,P23634,P02786 4 +Embryonic digit morphogenesis 0.4486434327139985 0.4967161662056247 0.6193892206257747 1.0 0.9660167681926284 7 Q07812,P42892 2 +Meiotic chromosome segregation 0.3565409878557458 0.4941893446533113 0.6211724642016516 1.0 0.9660167681926284 22 Q92791,P46379,Q9BTX1,Q9BXW9 4 +Regulation of ossification 0.428986854077663 0.4908462209348253 0.6235352161663501 1.0 0.9660167681926284 8 O75844,P20020 2 +Negative regulation of phosphatase activity 0.4800236389535541 0.4905324536752175 0.6237571706053331 1.0 0.9660167681926284 5 P04899 1 +Regulation of cellular respiration 0.360279440389863 0.4903292290013333 0.6239009470428472 1.0 0.9660167681926284 17 P14406 1 +Mammary gland epithelial cell proliferation 0.4565852794188266 0.4897189976335162 0.6243327567491406 1.0 0.9660167681926284 6 Q92766,Q9NQC3,Q07812,Q15648 4 +Regulation of osteoblast differentiation 0.4468120310585758 0.4890270910556538 0.6248225172938213 1.0 0.9660167681926284 7 Q13418,Q9H6W3 2 +Negative regulation of microtubule polymerization or depolymerization 0.4029802397149359 0.4887477552252249 0.6250202899045116 1.0 0.9660167681926284 11 Q9UJX6,Q8WWK9,Q7Z460,P29372,O15344,P16949,Q15691,Q9BTW9,Q92974,Q9ULW0 10 +Regulation of synaptic vesicle exocytosis 0.4108269174902469 0.4887239739585351 0.6250371285308063 1.0 0.9660167681926284 10 P16615 1 +Amide transport 0.3353062842245525 0.4885061753706544 0.6251913526751804 1.0 0.9660167681926284 39 Q03518,Q9H2D1,P07602,O95563,P08183,O00400,Q9NZJ7,P53985,P33527,P50416,P41440 11 +Cellular response to molecule of bacterial origin 0.3539982199991434 0.4880306021718695 0.6255281651905216 1.0 0.9660167681926284 23 P08670,Q9NUQ9,Q8WTV0 3 +Nucleotide binding domain leucine rich repeat containing receptor signaling pathway 0.6498599590382815 0.4866139815415002 0.6265319134708753 1.0 0.9665630722859954 3 Q96RT1 1 +Central nervous system neuron differentiation 0.3857396644898112 0.4861310941420018 0.6268742221896275 1.0 0.9667937253196084 13 Q9Y4G8,O94813,O14949 3 +Positive regulation of cell activation 0.3349220763075871 0.4851534612944076 0.6275674915382048 1.0 0.9667937253196084 39 P30825,P02786,Q5RKV6,P14174,Q08722,Q9HCL2,P49366,O00203,Q9NUQ9,P12956 10 +Vesicle mediated transport 0.3317037946301908 0.4851268327459602 0.6275863792597334 1.0 0.9667937253196084 324 Q9Y3E0,O43752,Q9Y2D4,Q14108,P16615,P40616,Q6NUQ1,P02786,Q4KMQ2,Q5VW38,O75955,P31751,Q8N2H4,Q08380,Q96PC5,O15127,Q12981,O43760,Q5BJH7,O60749,Q15363,P04899,P24390,P50897,P51790,Q8WTV0,Q9UP83,O15400,Q9UBG0,Q96RQ1,O95197,Q9Y5X1,Q08722,O15118,Q9BSR8,O43731,Q8WU17,Q5JRA6,P50570,P98194,Q13277,Q4J6C6,P09601,Q9BRK5,O75503,P51572,Q13432,Q9Y3B3,Q96PU5,Q5KU26,O00203,Q8NHH9,P61978,O14653,Q9Y282,O95249,O95070,Q9BVK6,O14976,Q9P2W9,Q05086,Q9NX40,Q8NC96,P83436,O60499,Q9UNK0,P41440 67 +Positive regulation of b cell proliferation 0.6488621740566645 0.4836770365061442 0.62861509275259 1.0 0.9679132223262316 3 P14174 1 +Folic acid metabolic process 0.4451536733344129 0.4820868900769579 0.6297442224730883 1.0 0.9685074476807968 7 Q9H2D1,P41440 2 +Autophagosome maturation 0.3589172560198711 0.481560807517454 0.6301179734301936 1.0 0.9685074476807968 16 Q8NHS3 1 +Regulation of axonogenesis 0.3588885603094712 0.4814703964253529 0.6301822147728293 1.0 0.9685074476807968 17 Q9NQC3,P07196,O94813 3 +Base excision repair ap site formation 0.6434108527131811 0.4792967919884275 0.6317275040350181 1.0 0.9685074476807968 2 P78549 1 +Macromolecule deacylation 0.3341071456481483 0.4780493992302859 0.6326150457203727 1.0 0.9685074476807968 39 Q8N163,Q9UMR5,P50897,Q9NUJ1 4 +Paranodal junction assembly 0.6427648578811397 0.4773199003337125 0.6331343423046647 1.0 0.9685074476807968 2 Q9Y2J2 1 +Cellular response to hydrogen peroxide 0.357514740761973 0.4744619022867518 0.6351705593672285 1.0 0.9685074476807968 18 Q99720 1 +Protein insertion into er membrane by stop transfer membrane anchor sequence 0.4527611988520568 0.4744524717572362 0.6351772828486126 1.0 0.9685074476807968 6 Q9P0I2 1 +Negative regulation of establishment of protein localization to mitochondrion 0.5188189946424958 0.4724442354742187 0.6366097363523298 1.0 0.969279907367799 4 O95817,O95429 2 +Response to gamma radiation 0.3570160949685131 0.4696814945722192 0.6385825910044827 1.0 0.9706697672133588 16 O75844,P12956,Q9NQ88 3 +Positive regulation of glucokinase activity 0.639857881136954 0.4684695970702541 0.6394488078355338 1.0 0.971262441226793 2 Q9UNI6 1 +Cellular response to osmotic stress 0.3899657568825226 0.4673801021781371 0.6402279560126978 1.0 0.9713692196303768 12 O95202,P16989 2 +Organ growth 0.3550487997780249 0.4671303762268132 0.6404066025207444 1.0 0.9713692196303768 20 O75844,P16989,Q8NDZ4,P07602,Q99956 5 +T cell mediated immunity 0.4148505910580778 0.4647595908591226 0.6421036286427579 1.0 0.9719881473286672 9 Q9NUQ9,O15400 2 +Cellular protein catabolic process 0.2965359334234722 0.4646460295388041 0.6421849637099379 1.0 0.9719881473286672 223 Q96HY6,P46379,Q9UL15,O15294,Q9BZK7,Q96K76,Q16740,Q8N511,P50897,Q8NHS3,Q9GZU8,P28070,Q96A33,Q14145,Q8WU17,Q8N163,Q8NBM8,P49721,P51572,Q96PU5,Q92530,O43791,Q13794,O75844,Q9UBV2,O00231,P28074,Q92575,Q9Y679,Q9UHG3,Q8IXB1,Q96TA2,O14773,Q9UJX3 34 +Regulation of synapse structure or activity 0.3239969935796394 0.4642247326209557 0.6424867431389756 1.0 0.9719881473286672 32 P07437,P50897,Q05086,Q9Y4F1,Q15375,Q13641,Q9UQB8 7 +Golgi to plasma membrane transport 0.3465741329697422 0.4639021806148642 0.6427178304434351 1.0 0.9719881473286672 25 Q9Y2D4,P50570,Q4J6C6,P98194,Q8N2H4,Q12955,Q9NV70,Q9BZG1 8 +Regulation of fertilization 0.6375968992248092 0.4616383127892475 0.6443407149193527 1.0 0.9719881473286672 2 P35579 1 +Embryonic appendage morphogenesis 0.404935086418792 0.4603020296894468 0.6452994445167874 1.0 0.9725768726434536 10 Q07812,Q9C0E8,Q9NR56,P42892,Q15648 5 +Epidermis development 0.3320143275132814 0.4598521947542192 0.6456223158423504 1.0 0.9727239135468604 39 O75844,Q9Y6M7,P16615,P98194,Q13510,O00203,Q08J23,P51648,Q14145 9 +Positive regulation of peptidyl tyrosine phosphorylation 0.3807686926097665 0.4586654413885758 0.6464744345654703 1.0 0.9727239135468604 13 Q13432 1 +Protein kinase c signaling 0.6399730627839423 0.4578199562408514 0.647081797204003 1.0 0.9727239135468604 3 P41440 1 +Post translational protein modification 0.3961143523564845 0.4541493669851452 0.6497213233376014 1.0 0.973281214048506 11 O75718,O60725,P46977,Q32P28 4 +Response to osmotic stress 0.3516185970328898 0.4511983133248264 0.6518466251797164 1.0 0.9741495581739562 21 O95202,P08183,Q8TDW0,P16989 4 +Negative chemotaxis 0.5114007763209261 0.4477432310150108 0.6543385178823036 1.0 0.974453239664481 4 O94813 1 +Positive regulation of small molecule metabolic process 0.3622839975778886 0.4460847735891435 0.6555360111181525 1.0 0.974453239664481 15 P31751,P00403,O75746,P50416,Q13794 5 +Negative regulation of secretion 0.362166068026547 0.4453858232185912 0.6560409555523832 1.0 0.974453239664481 15 P09601,Q16850 2 +Aspartate family amino acid metabolic process 0.3506981942839584 0.4449848794274319 0.6563306813323404 1.0 0.974453239664481 21 Q9BV57,Q9NRN7,Q9BQT8,O43175,Q13126,O75746,Q9UJS0 7 +Regulation of ligase activity 0.6352180936995133 0.4442223744601747 0.6568818172527648 1.0 0.974453239664481 3 P18887,Q13155 2 +Dna damage response signal transduction by p53 class mediator 0.3616102175756275 0.4420937695349574 0.6584213527683964 1.0 0.9758213596530364 15 O75844,Q13794 2 +Positive regulation of long term synaptic potentiation 0.6308139534883755 0.4414251190306491 0.6589052605901191 1.0 0.9760995424965712 2 Q99538 1 +Maintenance of protein location 0.3409993717246422 0.440384177586245 0.6596588826339445 1.0 0.976792982021652 26 O43731,P24390 2 +Regulation of vasoconstriction 0.6338202835275238 0.4402570445996525 0.6597509482189579 1.0 0.976792982021652 3 P42892 1 +Positive regulation of protein autophosphorylation 0.5084033613445396 0.4378920300397051 0.6614645533464154 1.0 0.976792982021652 4 O60934,Q92878,O00571 3 +Regulation of organic acid transport 0.3928432589472764 0.4378313222239275 0.6615085634693454 1.0 0.976792982021652 11 P14174,O75915,P31751 3 +Regulation of activin receptor signaling pathway 0.6295219638242928 0.4376236195745329 0.661659146324183 1.0 0.976792982021652 2 Q9Y2U8 1 +Activin receptor signaling pathway 0.6295219638242928 0.4376236195745329 0.661659146324183 1.0 0.976792982021652 2 Q9Y2U8 1 +Regulation of leukocyte proliferation 0.3493311469053243 0.435778199993393 0.6629976620826046 1.0 0.9778292823792504 21 P30825,Q9HCL2,P49366,P14174,Q96IZ0 5 +Female sex differentiation 0.399604577634192 0.4348720769684733 0.6636552837007104 1.0 0.9778292823792504 10 P57740,O95470,Q05086,O94813 4 +Response to endoplasmic reticulum stress 0.3531009112797967 0.4338449465380131 0.6644010402135345 1.0 0.9785870100571592 85 Q15363,Q9UBV2,P16615,P46379,Q96HY6,Q9H3N1,Q92575,P51572,O95831,Q7Z2K6,Q8IXB1,Q9Y679,Q96A33,P41440,Q13794,Q8WU17 16 +Acidic amino acid transport 0.3832018903885545 0.4319342635444135 0.6657891911292588 1.0 0.9797326665430932 12 O60831,O75746,Q8TDW0,O75915,Q9UJS0 5 +Synaptic vesicle endosomal processing 0.6308644534690809 0.431920506575039 0.6657991900141278 1.0 0.9797326665430932 3 O43752 1 +Regulation of metal ion transport 0.3411611010469257 0.4304965808766888 0.6668344533322399 1.0 0.9805373028557014 52 P04899,P50570,P23634,Q4KMQ2,P21796,Q96PU5,P20020,P27105,Q13586,P78417 10 +Regulation of lyase activity 0.4414150675286125 0.4298807196203004 0.6672824112086411 1.0 0.9805744116018604 6 Q13586 1 +Skeletal muscle organ development 0.3439008852432724 0.4295968900760741 0.6674888997221102 1.0 0.9805744116018604 24 P14649,P50402,P41440,P16989 4 +Regulation of stem cell differentiation 0.3754280468585178 0.4294633312440225 0.6675860736709078 1.0 0.9805744116018604 13 Q08J23,Q9NX40 2 +Regulation of cardiac conduction 0.4630217699618286 0.4283044803010217 0.6684294574650069 1.0 0.981555152633777 5 P20020,P16615 2 +Positive regulation of atp biosynthetic process 0.505195233621657 0.4274337876479583 0.6690634021300268 1.0 0.9817739172315404 4 P00403 1 +Positive regulation of nucleotide biosynthetic process 0.505195233621657 0.4274337876479583 0.6690634021300268 1.0 0.9817739172315404 4 P00403 1 +Adenylate cyclase inhibiting g protein coupled receptor signaling pathway 0.4064425422362683 0.4264766386821705 0.6697605672457592 1.0 0.9817739172315404 9 Q9NPQ8,P04899,P07602,Q9NZJ7 4 +Protein lipid complex assembly 0.4397531647488313 0.4234485770508793 0.6719680093237657 1.0 0.9834052373893464 6 Q9Y5X1 1 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.3811784336426264 0.4214294179659904 0.6734415413895678 1.0 0.9850815203369174 12 P50570,Q92896,Q8N0X7,Q13526,Q9UNH7 5 +Regulation of histone h2b ubiquitination 0.5031715058120482 0.4208829897197184 0.673840527005223 1.0 0.9852458435455016 4 Q5VTR2,P50750 2 +Negative regulation of mitochondrial fusion 0.6264451412262925 0.4195815457809779 0.6747911719647213 1.0 0.9859611151798184 3 Q99536 1 +Development of secondary sexual characteristics 0.5024837012871948 0.4186648602975365 0.6754610803187533 1.0 0.9863255416324076 4 Q07812,Q15648 2 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.4380112092638425 0.416734381804389 0.6768727030679065 1.0 0.9867532469104572 6 P14174 1 +Negative regulation of organic acid transport 0.5017085124684362 0.4161700057296736 0.6772856062955888 1.0 0.9869990155782938 4 O75915,P31751 2 +Negative regulation of protein containing complex assembly 0.3180044474388988 0.4133695144327087 0.6793359065845515 1.0 0.9883370452594626 32 P45880,Q9NUQ9,O94813 3 +Lymphocyte activation 0.3500347893029894 0.4125183189724251 0.6799595564316521 1.0 0.9885035893753084 91 P46379,P02786,O96005,Q9HCL2,P0CG08,P24390,Q5RKV6,Q9UJZ1,Q08722,P49366,Q9NQT5,P12956,Q9BXW9,Q07812,P78318,O00203,Q9NUQ9,Q96IZ0,Q9UQ84,P30825,P14174 21 +Body fluid secretion 0.3646807249900982 0.4120443714196318 0.680306901025576 1.0 0.9885035893753084 14 Q13505 1 +T cell proliferation 0.3431206152554115 0.4118705879767971 0.6804342796704508 1.0 0.9885035893753084 23 Q07812,P30825,P02786,Q9HCL2,P04439,P49366,Q96IZ0 7 +Negative regulation of mrna processing 0.3429709378786287 0.4108348097735298 0.6811936665719562 1.0 0.9885398010621542 23 P98175,P18615,P26368,O75494,O00422,P38159,Q16629,P61978,Q5VTR2,P50750 10 +T cell receptor signaling pathway 0.356269112575527 0.410668508536627 0.6813156214357774 1.0 0.9885398010621542 15 Q9NR50,Q9UJZ1 2 +Embryonic pattern specification 0.4361886922768268 0.4097406314708285 0.6819962208998982 1.0 0.9885398010621542 6 Q15363,Q9UK61 2 +Embryonic axis specification 0.4361886922768268 0.4097406314708285 0.6819962208998982 1.0 0.9885398010621542 6 Q15363,Q9UK61 2 +Regulation of heart rate by chemical signal 0.6198320413436658 0.4096240574906284 0.6820817464300668 1.0 0.9885398010621542 2 P09493 1 +Metencephalon development 0.328313390558173 0.4087855866701274 0.6826970182235343 1.0 0.9885398010621542 29 P54802,Q5KU26,Q9BRK5 3 +Regulation of systemic arterial blood pressure mediated by a chemical signal 0.4574041138499649 0.4083155058399708 0.683042056902688 1.0 0.9885398010621542 5 P42892 1 +Regulation of viral entry into host cell 0.4571613320400892 0.4074584694151786 0.68367129086385 1.0 0.9885398010621542 5 P07237,Q14258,P14373,Q92692 4 +Regulation of cellular carbohydrate metabolic process 0.3362725883147474 0.4055471601844564 0.685075360242567 1.0 0.9885398010621542 26 O75844,Q14108,P31751,O75746,Q9NQ88,Q13794 6 +Response to hydrogen peroxide 0.3361240740448127 0.4044585598195884 0.6858755453049898 1.0 0.9885398010621542 26 Q99720,P09601 2 +Regulation of cell killing 0.4091594356250624 0.4044307907777555 0.6858959617906826 1.0 0.9885398010621542 8 Q9NUQ9,O15400 2 +Cellular response to growth hormone stimulus 0.620584330312537 0.4034548141532733 0.6866136694713161 1.0 0.9885398010621542 3 P18031 1 +Growth hormone receptor signaling pathway via jak stat 0.620584330312537 0.4034548141532733 0.6866136694713161 1.0 0.9885398010621542 3 P18031 1 +Regulation of immune response 0.3453827174716574 0.403149629535773 0.6868381522960654 1.0 0.9885398010621542 101 Q9NPR9,P46379,O15400,Q96RT1,Q9NQC3,Q9NZ08,P09601,Q9UJZ1,O75955,P28070,Q5KU26,O00203,Q9NUQ9,Q9NR50,P12956,O43657,P41440 17 +Vasoconstriction 0.4974634020343345 0.4026044642326266 0.687239225007735 1.0 0.9885398010621542 4 P42892 1 +Positive regulation of tor signaling 0.4555773355156317 0.4018810555246728 0.6877715655316499 1.0 0.9885398010621542 5 Q9P2J5,Q96EE3,Q6IAA8 3 +Neuron recognition 0.6198431223770151 0.4014349175828623 0.688099945790317 1.0 0.9885398010621542 3 Q9NQC3 1 +Sequestering of triglyceride 0.6169250645994778 0.401404412409897 0.6881224013009879 1.0 0.9885398010621542 2 O60664 1 +Regulation of sequestering of triglyceride 0.6169250645994778 0.401404412409897 0.6881224013009879 1.0 0.9885398010621542 2 O60664 1 +Liver regeneration 0.3922846515923252 0.4004295843291295 0.6888401378098297 1.0 0.9886982522565728 10 P09601 1 +Neutrophil differentiation 0.4964447317388509 0.3993739502373409 0.6896176853575771 1.0 0.9886982522565728 4 Q14739,Q6IAN0,Q8N5M9 3 +Cd40 signaling pathway 0.4961826585275043 0.3985444034155768 0.690228934088547 1.0 0.9886982522565728 4 P35232,Q9BXW9 2 +Alcohol metabolic process 0.3497120177478953 0.3984792755001654 0.6902769319314117 1.0 0.9886982522565728 84 P61457,P48449,P04114,O15269,Q8WTV0,P37268,Q15392,Q13510,O15118,O60762,Q16850,Q15800,P51648,Q14534,O76062,P16435,Q9UNW1,Q10713,P30837,Q9HBH5 20 +Cellular modified amino acid metabolic process 0.3412708834152022 0.3984666014619309 0.6902862725639511 1.0 0.9886982522565728 57 Q9H7Z7,P16435,Q8NBM8,P23786,Q8NCC3,O60725,Q9UHG3,P41440,P50416,P78417 10 +Prostanoid biosynthetic process 0.4332216707957173 0.3984241205150958 0.6903175809178634 1.0 0.9886982522565728 6 Q9H7Z7 1 +Maternal process involved in female pregnancy 0.4242098089522584 0.3964483595172604 0.69177429659784 1.0 0.9886982522565728 7 Q15363,P35613,Q8IZL8 3 +Small gtpase mediated signal transduction 0.3489822408133415 0.3943791955490868 0.6933011012894288 1.0 0.9886982522565728 77 Q9Y4G8,Q02818,P50570,Q15047,Q96RT1,Q92766,P80303,P09601,Q4VCS5,Q5VZ89,Q15392,O94813,O75955,O15294,Q9NUQ9,Q96AG4,P41440 17 +Endocrine process 0.4518125664857614 0.3887252885466579 0.6974793732375681 1.0 0.9886982522565728 5 P42892 1 +Pteridine containing compound metabolic process 0.3438138741023324 0.3871005747322515 0.6986817521467621 1.0 0.9890732241197796 17 P61457,Q9H2D1,Q9NRN7,P41440 4 +Positive regulation of isotype switching to iga isotypes 0.6114341085271362 0.3861120437669856 0.6994136905495165 1.0 0.9890732241197796 2 O96028 1 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.450986079212024 0.3858564107429214 0.6996030145147598 1.0 0.9890732241197796 5 O43657 1 +Response to activity 0.3519802006449123 0.3857222669544363 0.6997023700033806 1.0 0.9890732241197796 15 O43819,Q9UDX5 2 +Regulation of steroid biosynthetic process 0.3816903306882048 0.3830824036724325 0.7016586661236641 1.0 0.9890732241197796 11 P16435,Q15637,Q13510,P04114 4 +Potassium ion import across plasma membrane 0.4494130265360097 0.3804155288832441 0.7036369891975669 1.0 0.9893207064611546 5 P05023,Q9BXP2 2 +Potassium ion homeostasis 0.4494130265360097 0.3804155288832441 0.7036369891975669 1.0 0.9893207064611546 5 P05023,Q9BXP2 2 +Lysine metabolic process 0.4902873534664287 0.3800561507680884 0.7039037344455645 1.0 0.9894787144289624 4 Q9BQT8 1 +Regulation of transporter activity 0.3214241566925322 0.3788355093151351 0.7048100167084006 1.0 0.9901012945651648 38 P27105,P08183,Q13586,P78417 4 +Protein localization to early endosome 0.4896574014221089 0.378100372392968 0.7053560316863234 1.0 0.9902109146279776 4 P35241,Q14160,P15311 3 +Positive regulation of establishment of protein localization to mitochondrion 0.3724525012641841 0.3766971345072794 0.7063986925924735 1.0 0.9902740077173934 12 P55786 1 +Maintenance of centrosome location 0.6078811369509081 0.3763827855663835 0.706632341856374 1.0 0.9902740077173934 2 P43034 1 +Maintenance of organelle location 0.6078811369509081 0.3763827855663835 0.706632341856374 1.0 0.9902740077173934 2 P43034 1 +Negative regulation of adaptive immune response 0.606589147286813 0.3728776707175191 0.7092394916472222 1.0 0.9917594113129788 2 P14373 1 +Immune response 0.2762666542885991 0.3688384564866688 0.7122481383736736 1.0 0.9927181054523262 188 Q03518,P46379,Q96RT1,O75955,O00584,Q9Y487,Q9NPR9,O15400,Q92667,Q9NQC3,Q9UJZ1,Q08722,P10321,P28070,Q9NVI7,P12956,P07437,Q9NZ08,P09601,P08670,Q5KU26,O00203,Q9NUQ9,Q96S55,Q9NR50,Q96IZ0,Q9UQ84,Q9UNK0,P14174,O43657,P41440 31 +Regulation of lipid localization 0.3391811213006431 0.3683113222257735 0.7126411110931699 1.0 0.992837704970537 21 Q9BZF3,P31751,Q8WTV0 3 +Hormone biosynthetic process 0.3931160350309924 0.3672890266266803 0.7134034384689207 1.0 0.992837704970537 9 P16435,Q53GQ0,P05023,Q15648 4 +Isotype switching to iga isotypes 0.6067851373182493 0.3665974766582291 0.7139192907072258 1.0 0.992837704970537 3 P43246,O96028 2 +Protein maturation 0.344387617640616 0.3663254407709275 0.7141222480129974 1.0 0.992837704970537 70 O75844,Q96F07,Q92896,Q9BU89,Q15392,Q9UJZ1,O75503,P42892,O75787,P49366,Q9UMS0,Q96TA2,P67812,Q10713,Q8WU17,O75976,Q9BXS4 17 +Negative regulation of dna binding transcription factor activity 0.3308539121093503 0.3660814647701867 0.7143042879366288 1.0 0.992837704970537 26 Q14145,Q96RT1,P09601 3 +Protein localization to ciliary membrane 0.6040051679586612 0.3659204786471166 0.7144244148097096 1.0 0.992837704970537 2 P36405 1 +Fatty acid beta oxidation using acyl coa oxidase 0.4163389480193701 0.3653419403334347 0.7148561749997195 1.0 0.992837704970537 7 O15254 1 +Meiotic cell cycle process 0.3160663510385568 0.3645087845778764 0.7154781152132248 1.0 0.992837704970537 35 Q08J23,P46379 2 +Intracellular protein transport 0.3204877424833345 0.3618071571283456 0.7174961433766858 1.0 0.9935515832889514 308 O43752,O43681,Q14108,P46379,Q99595,Q9BRK0,O60830,Q96RT1,P31751,O95831,Q9Y584,P27105,Q5BJH7,Q15363,P49458,Q9UGP8,Q9NS69,Q9Y5X1,O14737,O60725,Q15388,Q53H12,Q7Z4Q2,P62072,Q8N4H5,Q13277,O75381,P50402,P51572,P55786,Q9Y3B3,O00203,Q15629,Q9Y282,Q10713,P43307,Q9UBV2,O75298,Q9UI26,Q9P2W9,Q9Y5M8,O60499,Q9P0J0,Q9UNK0,Q15070 45 +Pyrimidine nucleotide catabolic process 0.6046551371875137 0.3610525781515808 0.7180601425575655 1.0 0.993688582425301 3 Q9H773 1 +Response to salt stress 0.3984967407881231 0.3595787943251694 0.7191621439749758 1.0 0.9941321259506408 8 O95202 1 +Regulation of cell cell adhesion 0.3245113079019008 0.357556294888169 0.7206753903319836 1.0 0.9941321259506408 43 Q5JRA6,P30825,O75955,Q08722,Q9HCL2,P49366,O00203,Q9NUQ9,Q15375,Q96IZ0,P41440 11 +Regulation of leukocyte mediated cytotoxicity 0.4139711127758817 0.356112044181404 0.7217566577672987 1.0 0.9941321259506408 7 Q9NUQ9,O15400 2 +Metaphase anaphase transition of cell cycle 0.3362681658611678 0.3560013731622313 0.7218395368297532 1.0 0.9941321259506408 22 P50748,Q9UJX3 2 +Pyramidal neuron development 0.6026359621728092 0.3558328333612857 0.7219657588072903 1.0 0.9941321259506408 3 O14949 1 +Rna stabilization 0.3242039167655406 0.3542465291235442 0.7231541362699498 1.0 0.9941321259506408 28 P98175,P16989,O95453,P67809,Q92804,P07910,P35637,Q08J23,O60506,Q9H814 10 +Caveolin mediated endocytosis 0.6019767184858122 0.3541364115858939 0.723236655484305 1.0 0.9941321259506408 3 Q13432 1 +Guanine nucleotide transport 0.6005840199008591 0.3505652720467527 0.72591451387625 1.0 0.9957440688950916 3 P41440 1 +Cyclic gmp amp transmembrane import across plasma membrane 0.6005840199008591 0.3505652720467527 0.72591451387625 1.0 0.9957440688950916 3 P41440 1 +Guanine nucleotide transmembrane transport 0.6005840199008591 0.3505652720467527 0.72591451387625 1.0 0.9957440688950916 3 P41440 1 +Lung associated mesenchyme development 0.5978682170542529 0.3496845287416615 0.7265754658048076 1.0 0.99600842205824 2 P35222 1 +Positive regulation of smoothened signaling pathway 0.4403223200420466 0.3494874257704062 0.7267234092031667 1.0 0.99600842205824 5 Q96J42,P16435,Q9BZG1 3 +Carbohydrate transport 0.3376176150847177 0.3488680245843912 0.7271883914722033 1.0 0.9962445754922972 18 Q16625,P31751 2 +Microtubule depolymerization 0.3664938431626742 0.3467243158437786 0.7287984407348025 1.0 0.9972140919796352 12 Q9UJX6,Q14008,Q8WWK9,Q7Z460,Q99661,P29372,P16949,O15344,Q86Y91,Q92974,Q9ULW0 11 +Protein ufmylation 0.4792980267148498 0.3465075850451053 0.7289612848445692 1.0 0.9972140919796352 4 Q96HY6 1 +Er nucleus signaling pathway 0.3598214413044566 0.3462067776007521 0.7291873215356013 1.0 0.9972457288336256 13 Q15363,P16615,P18031,Q96A33,Q9UM00 5 +Regulation of leukocyte apoptotic process 0.3586860048823057 0.3402840669013018 0.7336426147715733 1.0 1.0 13 Q9HCL2 1 +Polyadenylation dependent rna catabolic process 0.4097654439005839 0.3398712259442518 0.7339535064856135 1.0 1.0 7 Q96B26,Q9NQT5 2 +Phagolysosome assembly 0.4767291531997433 0.3388442757344395 0.734727045025817 1.0 1.0 4 P61106,Q9BZG1,Q9NVJ2 3 +Nervous system process 0.3436044163263864 0.338542675271788 0.7349542733121832 1.0 1.0 87 O75844,Q14108,P50897,Q9BRK0,Q13432,Q9UQB8,Q9H6K4,Q13641,O14773,P62072,P78417 11 +Detection of stimulus 0.3582142287396638 0.3378289729668886 0.7354920749225662 1.0 1.0 13 Q13432,Q8WTV0 2 +Regulation of extrinsic apoptotic signaling pathway 0.3244868389045129 0.3369565500210456 0.7361496546515118 1.0 1.0 27 P09601,Q9NQX7 2 +Regulation of fat cell differentiation 0.3924328647876776 0.3346496380701909 0.7378893959167225 1.0 1.0 8 Q8N4Q0 1 +Multicellular organism aging 0.3766999121243102 0.3291792794241526 0.7420201836125833 1.0 1.0 10 O75844 1 +Regulation of proteasomal ubiquitin dependent protein catabolic process 0.3232110109154767 0.3287531975847451 0.7423422413011944 1.0 1.0 45 Q8N163,Q96HY6,P46379,Q9UL15,P51572,Q14145 6 +Trna transport 0.4337678288883579 0.3277569202471354 0.7430954622344643 1.0 1.0 5 Q15388 1 +Response to monosaccharide 0.3178182665584055 0.3276241792591642 0.7431958377059096 1.0 1.0 29 Q9HCL2 1 +Maintenance of location 0.3359211067889896 0.327063243342402 0.7436200518360274 1.0 1.0 61 P24390,Q9H6V9,Q8WTV0,Q14534,O95202,Q9Y679,Q14145,O43731,P50416,P78417 10 +Positive regulation of dna methylation dependent heterochromatin assembly 0.4059620666306596 0.3253581388928644 0.7449100337539882 1.0 1.0 7 Q15047 1 +Positive regulation of chromatin organization 0.3757896683659774 0.3251140842274903 0.7450947298259076 1.0 1.0 10 Q15047 1 +Negative regulation of endoplasmic reticulum calcium ion concentration 0.4717190987649197 0.3241012525810451 0.7458613786478989 1.0 1.0 4 Q07812,P51572 2 +Attachment of mitotic spindle microtubules to kinetochore 0.3896080238325431 0.3231896135729281 0.7465516463666022 1.0 1.0 8 Q96DB5 1 +Negative regulation of rna splicing 0.3332026269649543 0.3218790920897766 0.7475442930510989 1.0 1.0 18 P98175,Q9UKA9,P26368,O75494,O00422,Q16629,P61978 7 +Lymphocyte mediated immunity 0.313835712957681 0.3207442726557185 0.7484041936749812 1.0 1.0 30 P07437,O15400,Q9UQ84,P02786,Q5RKV6,Q9NQT5,Q9NUQ9 7 +Proteoglycan biosynthetic process 0.4046983759741669 0.3205737819289087 0.7485334087736664 1.0 1.0 7 Q8NCH0,O94923 2 +Extracellular matrix disassembly 0.4117193088527079 0.3191934351821556 0.7495798347730815 1.0 1.0 6 P41440 1 +3 utr mediated mrna destabilization 0.4117076326002522 0.3191518384778424 0.7496113759533491 1.0 1.0 6 Q9HCE1,Q14103,Q92945,Q13148,Q92900 5 +Regulation of proteolysis 0.2729336639344946 0.3181545019669979 0.7503677431174642 1.0 1.0 155 Q9H2J4,Q96KC8,P46379,Q96HY6,Q96F07,Q96A26,Q9UL15,Q9NRR5,O15294,O95831,Q9NZJ7,Q96K76,O75915,Q15392,Q9Y5X1,O43464,Q9GZU8,O14737,Q14145,Q15375,Q8WU17,Q8N163,Q07812,P78318,Q92896,Q9UL46,P51572,Q6ZXV5,O43847,Q92530,O43791,O15372,Q13794,Q9BXS4,P16435,Q05086,Q9P0J0 37 +Fat cell differentiation 0.3289564289821119 0.3155842415010261 0.7523181003320392 1.0 1.0 23 Q9NZ08,Q8N4Q0,Q9BRK5,P31751 4 +Positive regulation of reactive oxygen species biosynthetic process 0.4687133846294133 0.3153876496748223 0.7524673428449187 1.0 1.0 4 P51790 1 +Regulation of dna methylation dependent heterochromatin assembly 0.3805788380862189 0.3135153021240698 0.7538891968660189 1.0 1.0 9 Q15047,Q8NEY8 2 +Organic hydroxy compound metabolic process 0.3296701330136013 0.3122770597943332 0.754829972574464 1.0 1.0 113 P61457,P48449,Q9BZF3,P04114,O14734,O15269,Q8WTV0,P37268,Q15392,Q13510,O15118,O60762,Q16850,Q9NQ88,P21964,Q15800,P51648,O75746,Q14534,O76062,P16435,P38435,Q9UNW1,Q9HBH5,Q10713,P30837 26 +Regulation of nadp metabolic process 0.4286779333642296 0.311227836060454 0.7556274230078359 1.0 1.0 5 Q9NQ88 1 +Lipid biosynthetic process 0.2835773665449888 0.3104970389508107 0.7561830108727112 1.0 1.0 149 Q9H7Z7,P48449,O95470,Q9NPH0,Q9HCL2,Q9BZF3,P04114,O14734,Q96G23,Q53GQ0,Q8WTV0,P37268,Q15392,Q13510,Q9Y6K0,Q8NCC3,Q16850,Q53H12,Q99943,Q9H3P7,Q15800,Q86YN1,O76062,Q14534,Q8TBX8,P16435,P14174,Q10713,Q8NBX0,Q06136 30 +Nls bearing protein import into nucleus 0.3864042944306288 0.3103151497366979 0.7563213115951655 1.0 1.0 8 Q7Z3B4,Q8NFH5,P52292 3 +Eye morphogenesis 0.3662681773810705 0.3099604016028842 0.7565910692491573 1.0 1.0 11 P54802,Q07812,Q9NUL3,Q8NBN7 4 +Dephosphorylation of rna polymerase ii c terminal domain 0.5820413436692506 0.3097394885455083 0.7567590709947631 1.0 1.0 2 Q96P16 1 +Positive regulation of neutrophil migration 0.4274167474943436 0.3071803651319863 0.758706089869223 1.0 1.0 5 P63000,O00429,Q8NE86,Q8NHP6 4 +Positive regulation of granulocyte chemotaxis 0.4274167474943436 0.3071803651319863 0.758706089869223 1.0 1.0 5 P63000,O00429,Q8NE86,Q8NHP6 4 +Heparan sulfate proteoglycan metabolic process 0.4657663703983546 0.3069417987308134 0.7588876729100691 1.0 1.0 4 Q7LGA3,O94923 2 +Heparan sulfate proteoglycan biosynthetic process 0.4657663703983546 0.3069417987308134 0.7588876729100691 1.0 1.0 4 Q7LGA3,O94923 2 +Regulation of dna directed dna polymerase activity 0.4008888691790178 0.3062677588866547 0.7594007851487736 1.0 1.0 7 Q9BRX5 1 +Regulation of protein exit from endoplasmic reticulum 0.3852005331875973 0.3055122310518297 0.7599760559595796 1.0 1.0 8 Q9GZP9,Q9Y385,Q8NBM4,P51572 4 +Striated muscle adaptation 0.4648586537800341 0.3043600822440259 0.7608535758074386 1.0 1.0 4 P16615,P23634 2 +Dna strand elongation involved in dna replication 0.3578007428750133 0.3039223306961836 0.7611870645837122 1.0 1.0 12 P33991 1 +G protein coupled receptor signaling pathway involved in heart process 0.5808333472517281 0.3018312475247841 0.7627807090376266 1.0 1.0 3 P04899 1 +Dendritic transport 0.4067216914723464 0.3015417579072974 0.763001412655089 1.0 1.0 6 Q14254,Q9NUL3,P23246 3 +Glycerolipid metabolic process 0.3381785850295211 0.3014645688540169 0.7630602639724464 1.0 1.0 72 Q8TBX8,Q9UBV2,Q8WTV0,Q9NPH0,Q9UJZ1,Q9HCL2,Q9Y6K0,Q96N66,Q9BZK7,Q8NCC3,O60762,P04114,Q96BW9,Q10713,Q53H12,P50416,Q99943,Q8IY17 18 +Negative regulation of peptide secretion 0.4249908199444599 0.2994497672978577 0.764596894339588 1.0 1.0 5 Q16836,Q8N183,Q8N5M9 3 +Axoneme assembly 0.4629196468285933 0.2988766003399685 0.7650342017389831 1.0 1.0 4 Q9NVR5,A0AVF1 2 +Response to bacterium 0.3273329051718052 0.2940961939586224 0.7686843991339241 1.0 1.0 54 Q96EE3,Q8WTV0,Q9Y4Y9,Q96RT1,Q9NZ08,Q9BTY2,P08670,Q5KU26,Q9NUQ9,P14174,Q9UQB8 11 +Leukocyte cell cell adhesion 0.3072729053785462 0.2917412014377309 0.7704845046909774 1.0 1.0 35 Q5JRA6,P30825,Q08722,Q9HCL2,O00203,P49366,Q9NUQ9,Q96IZ0 8 +Regulation of insulin receptor signaling pathway 0.3618350076788994 0.2895712805068562 0.772144240887588 1.0 1.0 11 Q8TBX8,P04899,Q9HCD5,O15294,P18031 5 +Macroautophagy 0.3385550562438649 0.2881419192825704 0.7732381057276965 1.0 1.0 88 O95817,Q8TBX8,P16615,Q96HY6,Q93050,Q8NHS3,O75396,Q9NRR5,O43464,P09601,P21796,Q9Y679,O15118,Q9Y487,Q9Y5K8,Q9NQ88,O15269 17 +Histamine transport 0.4583063994828718 0.2860047231435942 0.7748745040492298 1.0 1.0 4 P07948,Q9UNH7,P51809 3 +Histamine production involved in inflammatory response 0.4583063994828718 0.2860047231435942 0.7748745040492298 1.0 1.0 4 P07948,Q9UNH7,P51809 3 +Histamine secretion 0.4583063994828718 0.2860047231435942 0.7748745040492298 1.0 1.0 4 P07948,Q9UNH7,P51809 3 +Demethylation 0.3410864608847821 0.2837614745915479 0.7765931802201562 1.0 1.0 14 P16435,Q16850 2 +Regulation of cation transmembrane transport 0.317883589061582 0.2836288956988987 0.7766947905348025 1.0 1.0 45 Q04656,Q07812,P50570,P23634,Q4KMQ2,P21796,Q96PU5,Q8TAD4,P27105,Q13586,P78417 11 +Meiotic chromosome condensation 0.4560439560439576 0.2797831259659097 0.7796438984273149 1.0 1.0 4 Q9NTJ3,Q15021,Q15003 3 +Peptidyl proline hydroxylation 0.4004061560496852 0.2796852701016705 0.7797189802628517 1.0 1.0 6 O75718 1 +Cellular response to topologically incorrect protein 0.3105533526135832 0.2780869537650929 0.7809456103012167 1.0 1.0 39 Q15363,O95817,Q07812,Q96HY6,P46379,Q9GZP9,Q96JB5,Q9Y679,P18031,Q9Y4P3,Q6NTF9,Q7Z2K6 12 +Neuroblast proliferation 0.3649611398963709 0.2776563826805029 0.7812761460236435 1.0 1.0 10 P61026,O15031,Q9H0H5,O60341,P35222,P35221,Q96N67,P43034,Q92974 9 +Polyol metabolic process 0.3255106640911623 0.2770852117750858 0.7817146767272833 1.0 1.0 20 P61457,Q10713,Q13510,Q9UNW1 4 +Extrinsic apoptotic signaling pathway 0.3040009771459727 0.2757201737080808 0.7827629996465777 1.0 1.0 34 Q9P0J0,P09601,Q9NQX7 3 +Negative regulation of proteolysis 0.3313354003776286 0.2752504486842398 0.7831238307633703 1.0 1.0 63 Q8N163,P16435,Q96KC8,Q96HY6,P46379,Q92896,Q9UL15,Q15392,Q9GZU8,Q92530,Q96K76,Q9BXS4 12 +Negative regulation of chemotaxis 0.4542755394772332 0.2749624100427735 0.7833451179872621 1.0 1.0 4 P14174 1 +Copper ion transport 0.5685304551144224 0.2733594227289248 0.784576941255716 1.0 1.0 3 P35670 1 +Protein exit from endoplasmic reticulum 0.3240009044821221 0.2708668374932837 0.7864934516875179 1.0 1.0 21 Q9UBV2,Q9BVK6,Q96CS3,Q9GZP9,P51572,Q9Y679,Q8NBM4 7 +Regulation of phagocytosis 0.3236404073904578 0.2700494231428471 0.7871222313823114 1.0 1.0 16 Q08722,P50570,Q8WTV0 3 +Negative regulation of potassium ion transport 0.5667278651566237 0.2693142950781537 0.7876878325593488 1.0 1.0 3 Q96PU5 1 +Negative regulation of potassium ion transmembrane transport 0.5667278651566237 0.2693142950781537 0.7876878325593488 1.0 1.0 3 Q96PU5 1 +Glycerophospholipid biosynthetic process 0.3140133460013243 0.2690305620166401 0.7879061642925316 1.0 1.0 43 Q8TBX8,Q9NPH0,Q96N66,Q9Y6K0,Q9HCL2,O60762,Q10713,Q99943 8 +Coenzyme a biosynthetic process 0.3971045577873165 0.2684668777752218 0.7883399670421971 1.0 1.0 6 P16260 1 +Smooth muscle cell proliferation 0.32422657252878 0.2678689918180197 0.7888001626537728 1.0 1.0 19 P12956,P09601 2 +Cerebral cortex cell migration 0.3621505109560713 0.2656252180020954 0.7905278619399907 1.0 1.0 10 Q9NQC3,O94901,Q96N66,O94813 4 +Negative regulation of lipid storage 0.562984496124038 0.265498894228346 0.790625161579859 1.0 1.0 2 Q9BZF1 1 +Regulation of transforming growth factor beta activation 0.562984496124035 0.2654988942283394 0.7906251615798641 1.0 1.0 2 P08238 1 +Transforming growth factor beta activation 0.562984496124035 0.2654988942283394 0.7906251615798641 1.0 1.0 2 P08238 1 +Monosaccharide catabolic process 0.3436419048008208 0.2637984383049676 0.7919352380142342 1.0 1.0 13 Q9NQ88,P16278 2 +Forebrain generation of neurons 0.4132129400270066 0.262977916873766 0.7925675999953252 1.0 1.0 5 Q9Y4G8,O14949 2 +Positive regulation of cell adhesion 0.3223437544946502 0.2580314013686065 0.7963826728012537 1.0 1.0 53 Q53GQ0,P30825,P50570,P02786,Q13277,Q92766,O75955,P36404,Q9HCL2,Q08722,P49366,O00203,O95429,Q9NUQ9,Q13418,P41440 16 +Import into cell 0.3085538392040937 0.2580309065314963 0.796383054696844 1.0 1.0 29 Q9BXP2,P30825,O75955,Q15758,P31751,Q8TDW0,O75915,P41440 8 +Secondary metabolite biosynthetic process 0.4473433375301829 0.2564296887349691 0.7976190657444062 1.0 1.0 4 Q04656,Q9Y4G8 2 +Sno s rna metabolic process 0.3544448633523017 0.256276128267133 0.7977376287671047 1.0 1.0 11 O95453,Q5RKV6,Q9NQT5 3 +Cerebral cortex radially oriented cell migration 0.3719506609584524 0.2539630106164521 0.7995241346447315 1.0 1.0 8 Q9NQC3,O94901,Q96N66 3 +Telencephalon glial cell migration 0.3719506609584524 0.2539630106164521 0.7995241346447315 1.0 1.0 8 Q9NQC3,O94901,Q96N66 3 +Mammary gland duct morphogenesis 0.5592907140533412 0.2529744250819151 0.8002879763550712 1.0 1.0 3 Q15648 1 +Positive regulation of receptor mediated endocytosis 0.3716287521234781 0.2527420208207183 0.8004675738782872 1.0 1.0 8 P50897,P50570 2 +Regulation of response to cytokine stimulus 0.321541177501974 0.2524560031914389 0.8006886172564391 1.0 1.0 18 Q9NZI8,Q7Z434,Q14166,Q86Y07,O94813,P18031,Q99943,Q15648 8 +Regulation of rho protein signal transduction 0.3531310389541842 0.2504520896218106 0.8022377511172267 1.0 1.0 11 P41440 1 +Protein localization to nuclear envelope 0.3916558861578195 0.2502764257464507 0.8023735859775158 1.0 1.0 6 Q9NVM9,Q9BZF1,Q5JTV8,P53350,Q7Z3B4 5 +Postsynaptic actin cytoskeleton organization 0.5568823878475403 0.247805145835629 0.8042851732910392 1.0 1.0 3 Q9Y4F1 1 +Regulation of lipid kinase activity 0.3844310955199109 0.2466100789247894 0.8052100035758583 1.0 1.0 7 Q8TBX8 1 +Somatic diversification of immunoglobulins involved in immune response 0.3337870150849614 0.2460287399546039 0.8056599848732588 1.0 1.0 14 Q5RKV6,Q9UQ84,P02786 3 +B cell activation involved in immune response 0.3337870150849614 0.2460287399546039 0.8056599848732588 1.0 1.0 14 Q5RKV6,Q9UQ84,P02786 3 +Immunoglobulin production involved in immunoglobulin mediated immune response 0.3337870150849614 0.2460287399546039 0.8056599848732588 1.0 1.0 14 Q5RKV6,Q9UQ84,P02786 3 +Trna methylation 0.3574167401822935 0.2456463499977897 0.8059560062024014 1.0 1.0 10 Q7L0Y3,Q08J23,O75648 3 +Negative regulation of transforming growth factor beta production 0.553294573643416 0.2446853666776038 0.8067000593849774 1.0 1.0 2 P08238 1 +Positive regulation of phosphorus metabolic process 0.3246658471848236 0.2445563612547514 0.8067999567594999 1.0 1.0 112 Q96HY6,P02786,O75955,P31751,P00403,Q9Y4G8,Q9UJZ1,Q9Y5X1,Q86XL3,P14635,Q15375,Q9H7B4,P12956,Q9NQ88,Q13418,P23634,Q8NDZ4,Q13432,O95429,O75746,Q99627,P14174,P41440 23 +Pyroptosis 0.5513565891472947 0.2406616182844274 0.8098173888817948 1.0 1.0 2 Q9NZI8 1 +Regulation of atp metabolic process 0.30868436851092 0.2402189524322805 0.8101605218641157 1.0 1.0 28 P14406,P00403,O75746,Q9BSK2,Q9NQ88 5 +Neurotransmitter uptake 0.387976429158916 0.2382270560661628 0.8117049933961658 1.0 1.0 6 P41440 1 +Mitochondrial dna replication 0.3817452981347364 0.2372267471139758 0.8124808872710045 1.0 1.0 7 Q9BQP7,Q9UJZ1 2 +Regulation of leukocyte chemotaxis 0.3250575537588942 0.2362358488316737 0.8132496632732495 1.0 1.0 15 Q4KMQ2,P14174,O94813 3 +Ethanol metabolic process 0.4394543763680876 0.2360636176464498 0.8133833050580108 1.0 1.0 4 P30837 1 +Establishment of lymphocyte polarity 0.5508873906158075 0.2352001119043308 0.8140534191453817 1.0 1.0 3 Q14254 1 +Activation of phospholipase d activity 0.5508802060491378 0.2351852321478751 0.8140649676102107 1.0 1.0 3 P40616 1 +Negative regulation of actin filament polymerization 0.3185058277209969 0.234873651647278 0.8143068005020346 1.0 1.0 18 Q9UEY8,Q9NUQ9,O94813,P35611 4 +Tooth mineralization 0.4386585501096541 0.2340529008511599 0.814943910061233 1.0 1.0 4 Q13586 1 +Protein localization to plasma membrane 0.3292979842929318 0.2337781914884361 0.8151571811511253 1.0 1.0 68 O75955,Q5VZ89,P31751,Q8N2H4,Q13641,O75915,O00264,Q15363,Q9Y4G8,O15400,P23634,Q4J6C6,Q13277,P98194,O95429,Q9BXS4,O14976,P35613,Q9UNK0,P41440 20 +Regulation of vascular permeability 0.3806488497554543 0.2334260439127177 0.8154305915625106 1.0 1.0 7 Q16625 1 +Positive regulation of nf kappab transcription factor activity 0.3172533129103012 0.2331979146148359 0.8156077251128329 1.0 1.0 22 P40763,Q96HY6,P02786,P23396,O75955,Q14254,Q92974,P14373,P41440 9 +Bone development 0.3180799797167135 0.2319591327651376 0.816569755462333 1.0 1.0 20 O75844,P16435,Q92896 3 +Cellular response to vitamin d 0.4026834415924564 0.2319365344244864 0.8165873077664436 1.0 1.0 5 P20020,Q8TB36,Q15648 3 +Morphogenesis of a branching structure 0.3173404606922586 0.2307588905096249 0.8175021199220152 1.0 1.0 17 Q15363,Q9NQC3,O94813,Q14344,Q15375 5 +Protein localization to organelle 0.3132547863619129 0.230017828059647 0.8180779163228045 1.0 1.0 308 O43615,O43681,Q14108,P46379,Q96HY6,P02786,Q99595,O60830,Q9P0I2,Q8N2H4,P57740,O95831,Q9Y584,Q9NVN8,O94901,O14925,P49458,Q9NPA0,P24390,Q9NQC3,Q9UGP8,Q9NS69,O43464,O14737,Q15005,Q15388,Q96A33,O43731,Q53H12,Q7Z4Q2,P62072,P52292,P50991,O95817,P50748,Q8N4H5,Q8N1F7,Q5JRA6,O75381,P51572,P55786,O00203,Q9Y5K8,Q15629,Q9Y6C9,P60602,Q10713,Q96DY7,O14976,Q9UI26,Q9Y5M8,Q13561,P83436,P67809,Q7Z3B4,Q8NEY8,Q9Y679,Q9P0J0,O14773,P40616,Q15070 61 +Positive regulation of biomineralization 0.5478071341667404 0.2288707355634978 0.8189693865245284 1.0 1.0 3 P20020 1 +N acylethanolamine metabolic process 0.5445736434108582 0.226946762610578 0.8204651392816438 1.0 1.0 2 Q9NZC3 1 +Ethanolamine containing compound metabolic process 0.5445736434108582 0.226946762610578 0.8204651392816438 1.0 1.0 2 Q9NZC3 1 +Presynaptic modulation of chemical synaptic transmission 0.5466882067851244 0.2265964628271272 0.8207375430130273 1.0 1.0 3 P35268,P05771 2 +Embryonic hemopoiesis 0.4348854397317706 0.224630856009346 0.8222664586401345 1.0 1.0 4 Q9H6E4 1 +Reticulophagy 0.4346818554506765 0.224127719110543 0.8226579243412464 1.0 1.0 4 Q96HY6 1 +Positive regulation of lymphocyte mediated immunity 0.3227556844864882 0.2241206859154099 0.8226633968323271 1.0 1.0 15 O15400,P02786,Q5RKV6,Q9NUQ9,Q9NQT5 5 +Developmental maturation 0.301071020821222 0.2211631692754999 0.8249653858285704 1.0 1.0 37 P51790,Q96JM7,P07196,O75503,O75787,Q08J23 6 +Spinal cord development 0.3455635541752379 0.2174980508798809 0.8278202258172054 1.0 1.0 11 O95817,P07196,O43175 3 +Regulation of dephosphorylation 0.3126058518735128 0.2168310792499599 0.8283399903651882 1.0 1.0 24 Q86XL3,P04899,P78318 3 +Retina development in camera type eye 0.3211400146125738 0.215688491571943 0.8292305724797091 1.0 1.0 15 Q07812,P23634,P54802,P20020,Q8NBN7 5 +Engulfment of apoptotic cell 0.538759689922486 0.2156497946827067 0.8292607383533324 1.0 1.0 2 P63000 1 +Axonal transport of mitochondrion 0.4310166830127449 0.2151623530996193 0.8296407413745546 1.0 1.0 4 P07196 1 +Neutrophil activation involved in immune response 0.5384366925064676 0.2150346511639013 0.8297403027094288 1.0 1.0 2 P51809 1 +Neutrophil degranulation 0.5384366925064676 0.2150346511639013 0.8297403027094288 1.0 1.0 2 P51809 1 +Negative regulation of g protein coupled receptor signaling pathway 0.3804803180309614 0.2142860513855579 0.8303239947939514 1.0 1.0 6 P04899,P50570 2 +Amelogenesis 0.5397920159601404 0.2128750528183959 0.8314244213682624 1.0 1.0 3 Q13586 1 +Enamel mineralization 0.5397920159601404 0.2128750528183959 0.8314244213682624 1.0 1.0 3 Q13586 1 +Mesonephros development 0.3799527141646222 0.2126324397496438 0.8316136667390792 1.0 1.0 6 O94813 1 +Negative regulation of small gtpase mediated signal transduction 0.3492272224528619 0.2119697102134936 0.8321306651103593 1.0 1.0 10 Q9NUQ9 1 +Glomerular epithelium development 0.536175710594321 0.210765466285822 0.8330702871078237 1.0 1.0 2 P80723 1 +Glomerular epithelial cell differentiation 0.536175710594321 0.210765466285822 0.8330702871078237 1.0 1.0 2 P80723 1 +Glomerulus development 0.536175710594321 0.210765466285822 0.8330702871078237 1.0 1.0 2 P80723 1 +Regulation of protein polymerization 0.3182463543692295 0.209094489038268 0.8343744767340748 1.0 1.0 55 Q16625,Q9Y5X1,O94813,P45880,Q9NUQ9,Q9UEY8,Q9UQB8 7 +Cellular response to vitamin 0.378648990565671 0.20856439436147 0.8347883084443892 1.0 1.0 6 P20020,Q8TB36,Q15648 3 +Regulation of autophagy 0.3306446017060133 0.2084232273212127 0.8348985217559353 1.0 1.0 84 O75844,Q93050,Q8NHS3,P09601,P07602,P21796,O15118,Q9Y487 8 +Response to dexamethasone 0.3538634030576166 0.2063642484537368 0.8365063953573117 1.0 1.0 9 P16435,P25705,Q9H7B4 3 +Axis elongation 0.426955397543635 0.205435130946086 0.8372321750324088 1.0 1.0 4 Q93074,Q15648,Q13308 3 +Positive regulation of nucleotide metabolic process 0.3773619315241282 0.2045737470061647 0.8379051684413354 1.0 1.0 6 P00403 1 +Positive regulation of atp metabolic process 0.3773619315241282 0.2045737470061647 0.8379051684413354 1.0 1.0 6 P00403 1 +Negative regulation of establishment of protein localization 0.3070039422135444 0.1998899899506099 0.8415666193202793 1.0 1.0 26 O95817,Q9GZP9,O95429,Q8NBM4,P30040,Q16850,Q6WKZ4,Q16836 8 +Maternal placenta development 0.3909514113384078 0.1992005384021321 0.8421058782778825 1.0 1.0 5 Q15363 1 +Histone h3 k4 demethylation 0.5325458144223085 0.1990100391577369 0.8422548915558756 1.0 1.0 3 Q9H6W3 1 +Response to vitamin d 0.3755421548958472 0.198974795765492 0.8422824604390047 1.0 1.0 6 P20020,Q8TB36,Q15648 3 +B cell mediated immunity 0.3105944405534444 0.1979381636083613 0.8430934446166081 1.0 1.0 16 Q5RKV6,Q9UQ84,P02786 3 +Myotube differentiation 0.3241457417397296 0.1978698024932234 0.8431469311454449 1.0 1.0 14 Q9H7B4,P41440 2 +Regulation of long term synaptic potentiation 0.5318255250403767 0.1976630271421524 0.8433087189796784 1.0 1.0 3 O95793,Q99538 2 +Intrinsic apoptotic signaling pathway 0.3280497457855315 0.1957765651074929 0.8447850534422832 1.0 1.0 76 Q8N163,P46379,P16989,Q9UL15,P09601,P45880,O95831,Q8IXB1,Q96K76,Q9P0J0,P14174,Q13794 12 +Muscle hypertrophy in response to stress 0.5305491893234988 0.1952900712817523 0.8451658694004438 1.0 1.0 3 P16615 1 +Asymmetric neuroblast division 0.5305331179321396 0.1952603049798544 0.8451891709390418 1.0 1.0 3 P61026,Q92974 2 +Neuroblast division 0.5305331179321396 0.1952603049798544 0.8451891709390418 1.0 1.0 3 P61026,Q92974 2 +Response to transforming growth factor beta 0.3041845332135668 0.1934827335871116 0.8465809271677203 1.0 1.0 27 Q92896 1 +Forebrain cell migration 0.3394159729305386 0.1915072161866482 0.8481282274702786 1.0 1.0 11 Q9NQC3,O94901,Q96N66,O94813 4 +Regulation of tau protein kinase activity 0.525193798449616 0.1909479045944427 0.8485664081660644 1.0 1.0 2 P08238 1 +Positive regulation of tau protein kinase activity 0.525193798449616 0.1909479045944427 0.8485664081660644 1.0 1.0 2 P08238 1 +Positive regulation of actin filament polymerization 0.3328125791120043 0.1880766971308343 0.8508165281037443 1.0 1.0 12 Q9UQB8 1 +Negative regulation of nervous system development 0.3152807781843983 0.1856226205564316 0.8527407132113483 1.0 1.0 15 Q9Y4G8,P35222,Q9NQC3,Q8N0X7,P35221,Q15375,Q96G23 7 +Alpha beta t cell proliferation 0.5250344896663677 0.1852423268173521 0.8530389715419149 1.0 1.0 3 P04439 1 +Mesoderm development 0.3378684807256207 0.1850802409805386 0.8531660992742651 1.0 1.0 11 P05556,Q9BYW2,Q9Y2G5,P06744,Q14696,Q8WUM0,Q9HCM4,P10644,P17252,P63173 10 +Cellular potassium ion homeostasis 0.4179056237879787 0.1845570831318641 0.8535764502778924 1.0 1.0 4 P55011,P54709,P05023 3 +Regulation of post translational protein modification 0.5238517591422952 0.1831309190541029 0.8546952960955634 1.0 1.0 3 O75718 1 +Glial cell differentiation 0.295555746221034 0.1828574758816178 0.8549098495747727 1.0 1.0 30 Q9NR50,P31751 2 +Modulation by host of symbiont catalytic activity 0.5200258397932912 0.1821496547347317 0.8554652816339499 1.0 1.0 2 P51151 1 +Neural plate development 0.5187338501292077 0.1800028151772962 0.8571503581073199 1.0 1.0 2 P35222 1 +Foregut morphogenesis 0.5187338501292077 0.1800028151772962 0.8571503581073199 1.0 1.0 2 P35222 1 +Ectoderm development 0.5187338501292077 0.1800028151772962 0.8571503581073199 1.0 1.0 2 P35222 1 +Paraxial mesoderm development 0.5187338501292025 0.1800028151772879 0.8571503581073263 1.0 1.0 2 Q8WUM0 1 +Protein localization to chromosome centromeric region 0.3260170833208603 0.1796008058638957 0.8574659719821418 1.0 1.0 13 Q96DY7 1 +Neuroepithelial cell differentiation 0.5216914276169116 0.1793140909192936 0.8576910832162714 1.0 1.0 3 P07437 1 +Estrogen metabolic process 0.3643657740623418 0.1791267473474494 0.8578381803114752 1.0 1.0 7 Q53GQ0 1 +Leukocyte proliferation 0.2915391969425708 0.1772705845745608 0.8592958549570644 1.0 1.0 34 Q07812,P30825,P02786,Q9NRZ9,Q9HCL2,P04439,P49366,P14174,Q96IZ0 9 +Negative regulation by host of viral process 0.5201938610662238 0.1766984429023056 0.8597452640147321 1.0 1.0 3 P17980,Q9P0L0 2 +Positive regulation of epithelial cell proliferation 0.3073178190896586 0.1756116679403812 0.860599035124773 1.0 1.0 17 Q04656,Q9H2J4,P40763,Q92766,Q9NQC3,P09601 6 +Positive regulation of rho protein signal transduction 0.5158268733850128 0.1752494201815919 0.8608836534572377 1.0 1.0 2 P63000 1 +Response to copper ion 0.3675832516477322 0.1750979344433583 0.8610026812741385 1.0 1.0 6 Q04656,P35670,Q00796,P02786 4 +Positive regulation of neurotransmitter secretion 0.5155038759689994 0.1747278396163022 0.8612934914230266 1.0 1.0 2 Q00535 1 +Platelet derived growth factor receptor signaling pathway 0.413101889367089 0.1739295272786987 0.8619208468806467 1.0 1.0 4 O95470 1 +Regulation of ire1 mediated unfolded protein response 0.3625793418998981 0.1734248101442982 0.8623175248931745 1.0 1.0 7 Q07812,Q96HY6 2 +Establishment of endothelial intestinal barrier 0.3617477851916075 0.1707885590329759 0.8643900254677845 1.0 1.0 7 Q9Y4G8,P55196,Q9H0U4 3 +Zinc ion homeostasis 0.3799729879755305 0.1704279714657185 0.8646735758675312 1.0 1.0 5 O00203,P35670 2 +Positive regulation of b cell activation 0.3386540129170992 0.1702772120209666 0.8647921317141543 1.0 1.0 10 Q5RKV6,P14174,P02786 3 +Trna wobble uridine modification 0.4111932301239517 0.1697956181055458 0.8651708731354675 1.0 1.0 4 O75648 1 +Regulation of alternative mrna splicing via spliceosome 0.2877519839900366 0.1694515431611841 0.8654414840523508 1.0 1.0 32 P98175,Q8IY67,O75525,O00422,Q9NR56,Q9H0G5,P62995,Q9UHX1,P38159,Q92879 10 +Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.3382690290597258 0.1687992383952604 0.8659545574018053 1.0 1.0 10 Q13794,O60313,P30040,P18031 4 +Regulation of lymphocyte activation 0.3088968948636038 0.1680949150297447 0.866508609651131 1.0 1.0 50 P30825,P02786,Q5RKV6,O96005,P14174,Q08722,Q9HCL2,P49366,O00203,Q9NUQ9,P12956,Q96IZ0,Q9BXW9 13 +Inflammasome complex assembly 0.5109819121447121 0.1675634964642628 0.8669266906890731 1.0 1.0 2 P19525 1 +Positive regulation of chemokine c c motif ligand 5 production 0.510981912144705 0.1675634964642519 0.8669266906890818 1.0 1.0 2 Q7Z434 1 +Neurotrophin signaling pathway 0.3784232632041864 0.1665161303499381 0.8677507901951593 1.0 1.0 5 Q96F07 1 +Ncrna catabolic process 0.3061886809516229 0.1657460468842831 0.8683568070263665 1.0 1.0 22 Q99575,Q5RKV6,O95453,Q08J23,Q96B26,Q9NQT5 6 +Ire1 mediated unfolded protein response 0.3473612858303458 0.165463691378144 0.8685790259625286 1.0 1.0 8 Q07812,Q96HY6 2 +Regulation of protein localization to cell periphery 0.293129807644889 0.1653217275154156 0.8686907580366137 1.0 1.0 30 O15400,Q13277,P98194,O00264,Q9UNK0,Q9BXS4 6 +Negative regulation of t cell proliferation 0.3641655886157754 0.1651571235132366 0.8688203122221696 1.0 1.0 6 Q92990,P78540,Q14160,Q96J02,Q96IZ0 5 +Positive regulation of protein k63 linked ubiquitination 0.5093669250646096 0.1650670078436064 0.8688912406786045 1.0 1.0 2 O00571 1 +Negative regulation of nervous system process 0.508720930232562 0.1640775575691797 0.869670088830649 1.0 1.0 2 Q13614 1 +Negative regulation of myelination 0.508720930232562 0.1640775575691797 0.869670088830649 1.0 1.0 2 Q13614 1 +Axon development 0.3159896961206377 0.1640175481428333 0.8697173294689478 1.0 1.0 59 Q9NQC3,P07196,O75955,O94813,Q9BVA1,Q15375,P42892,Q9UQB8,P41440,Q96G23 10 +Hypothalamus development 0.376023230751367 0.1605323429220302 0.87246174602632 1.0 1.0 5 O14949 1 +Fertilization 0.2878936743812638 0.159900566755481 0.8729594020582832 1.0 1.0 33 P16989,Q05086,P45880,O00203,P04114,P50991 6 +Positive regulation of t cell receptor signaling pathway 0.5045219638242979 0.157773168532272 0.8746355422244323 1.0 1.0 2 P23396 1 +Adhesion of symbiont to host cell 0.5045219638242938 0.1577731685322661 0.874635542224437 1.0 1.0 2 P08238 1 +Virion attachment to host cell 0.5045219638242938 0.1577731685322661 0.874635542224437 1.0 1.0 2 P08238 1 +Positive regulation of mast cell activation 0.5045219638242892 0.1577731685322593 0.8746355422244423 1.0 1.0 2 P51809 1 +Regulation of mitotic recombination 0.5082390953150195 0.1567081921606073 0.8754748304458349 1.0 1.0 3 Q92878,Q15554 2 +Regulation of camp mediated signaling 0.5073608319655061 0.155302072627251 0.8765831817201915 1.0 1.0 3 Q9Y4G8 1 +Lamellipodium morphogenesis 0.3731448162852623 0.1534760028086132 0.878022913081479 1.0 1.0 5 O60749 1 +Positive regulation of histone ubiquitination 0.3731005496281971 0.1533685133432488 0.8781076738074518 1.0 1.0 5 O60341,Q5VTR2,O75150,P50750 4 +Plasma membrane tubulation 0.5054679755490042 0.1523006595942561 0.8789498047084601 1.0 1.0 3 Q9Y5X1 1 +Negative regulation of interleukin 2 production 0.5003229974160243 0.1516880305693184 0.8794329981457709 1.0 1.0 2 P14373 1 +Sphingolipid mediated signaling pathway 0.5003229974160218 0.151688030569315 0.8794329981457736 1.0 1.0 2 P63000 1 +Positive regulation of antigen receptor mediated signaling pathway 0.5046849757673519 0.1510707133287869 0.8799199346984683 1.0 1.0 3 P23396,P05771 2 +Response to axon injury 0.3291233318807446 0.1496769096100735 0.8810195263936624 1.0 1.0 11 P07196,Q07812,Q96G23 3 +Apoptotic dna fragmentation 0.3577668247441405 0.147064771362289 0.8830808958655705 1.0 1.0 6 O95831,Q07812 2 +Deoxyribonucleoside monophosphate catabolic process 0.5020795233373655 0.1470269789082483 0.883110725634634 1.0 1.0 3 P16260 1 +Negative regulation of immune system process 0.2952807669953747 0.1465224277081445 0.8835089862293763 1.0 1.0 40 Q5JRA6,P09601,Q08722,Q9HCL2,O94813,P28070,P14174 7 +Negative regulation of blood circulation 0.5016894435748982 0.1464280401038568 0.8835834930671922 1.0 1.0 3 P16615 1 +Regulation of anaphase promoting complex dependent catabolic process 0.4958010335917422 0.1453782472048899 0.8844122384111779 1.0 1.0 2 P24941 1 +Endoplasmic reticulum plasma membrane tethering 0.4998384491114658 0.1436089502205581 0.88580927267027 1.0 1.0 3 O95292,Q9BSJ8 2 +Endoplasmic reticulum localization 0.4998384491114658 0.1436089502205581 0.88580927267027 1.0 1.0 3 O95292,Q9BSJ8 2 +Cellular response to ether 0.493863049095617 0.142750808593568 0.8864869881345527 1.0 1.0 2 P11802 1 +Regulation of er associated ubiquitin dependent protein catabolic process 0.4990464632775914 0.1424143335652343 0.8867527412350897 1.0 1.0 3 P51572 1 +Negative regulation of dephosphorylation 0.340327118521311 0.142067319326872 0.8870268317033254 1.0 1.0 8 P04899 1 +Ventral spinal cord development 0.4932170542635769 0.1418851779576558 0.8871707021412458 1.0 1.0 2 Q14203 1 +Regulation of ion transport 0.3223402224676874 0.140674255208914 0.8881272841834456 1.0 1.0 77 O75844,P04899,P50570,P0CG08,P21796,Q96PU5,P08183,P27105,P14174,Q13586,O75915,P78417 12 +Negative regulation of muscle tissue development 0.4974957614783894 0.1400953818381105 0.8885846293690884 1.0 1.0 3 P16989 1 +Negative regulation of muscle organ development 0.4974957614783894 0.1400953818381105 0.8885846293690884 1.0 1.0 3 P16989 1 +Regulation of skeletal muscle cell differentiation 0.4972536348949884 0.1397357010515061 0.8888688177686386 1.0 1.0 3 Q92841,Q9BYT8 2 +Endoplasmic reticulum unfolded protein response 0.3010272622181795 0.138925291017286 0.8895091854167716 1.0 1.0 23 Q15363,Q07812,Q96HY6,Q9GZP9,Q96JB5,P18031,Q9Y4P3,Q6NTF9,Q7Z2K6 9 +Cellular response to thyroid hormone stimulus 0.4966074313408632 0.1387789336002801 0.8896248414301529 1.0 1.0 3 P35241,Q15648 2 +Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 0.4966074313408543 0.1387789336002668 0.8896248414301633 1.0 1.0 3 P42765,P05141 2 +Nadh oxidation 0.4896640826873373 0.137214780801044 0.8908610280272049 1.0 1.0 2 P43304 1 +Response to growth hormone 0.3946978817043298 0.1362034148431573 0.8916604756730355 1.0 1.0 4 P18031 1 +Regulation of establishment of protein localization to mitochondrion 0.2997139689387514 0.1355636569211707 0.8921662377326924 1.0 1.0 17 O95817,O14737,P55786,O43464 4 +Response to ether 0.4940226171243769 0.1349979833275915 0.8926134688071703 1.0 1.0 3 Q14103,P11802 2 +Regulation of b cell receptor signaling pathway 0.4874031007752051 0.1343220886359561 0.8931478873116792 1.0 1.0 2 P05771 1 +Negative regulation of myeloid leukocyte differentiation 0.4874031007751956 0.1343220886359444 0.8931478873116885 1.0 1.0 2 P35222 1 +Cellular response to radiation 0.2971550616729754 0.133479559192693 0.8938141290080006 1.0 1.0 43 O75844,P12956,P31751 3 +Leukocyte mediated immunity 0.2971469578662802 0.1334167462641286 0.89386380219863 1.0 1.0 43 P07437,O15400,Q9UQ84,P02786,Q5RKV6,P09601,Q9NUQ9 7 +Mesoderm morphogenesis 0.3375404530744404 0.1330533584229229 0.8941511816720162 1.0 1.0 8 P05556,Q9BYW2,Q9Y2G5,P06744,Q9HCM4,P10644,P17252 7 +Regulation of protein localization to chromatin 0.3924580072388429 0.1319401546426486 0.8950316274339658 1.0 1.0 4 Q96FF9 1 +Proteoglycan metabolic process 0.3371628619314949 0.1318433213332372 0.8951082201493099 1.0 1.0 8 Q8NCH0,O94923 2 +Regulation of response to endoplasmic reticulum stress 0.2989953656867899 0.1318262059561394 0.895121758084378 1.0 1.0 24 Q07812,Q96HY6,P46379,P51572,O60313,Q13794 6 +Regulation of protein localization to endosome 0.4894991922455421 0.1285585015360722 0.8977070047147289 1.0 1.0 3 P35241,P15311 2 +Positive regulation of protein localization to early endosome 0.4894991922455421 0.1285585015360722 0.8977070047147289 1.0 1.0 3 P35241,P15311 2 +Folic acid containing compound metabolic process 0.3092552811395189 0.1277253781538644 0.8983663057191809 1.0 1.0 14 Q9H2D1,Q9NRN7,P41440 3 +Embryonic body morphogenesis 0.48094315245479 0.1263936835532109 0.8994203018503626 1.0 1.0 2 Q7Z460 1 +Execution phase of apoptosis 0.313805974579591 0.1252942665120107 0.9002905910767502 1.0 1.0 13 Q07812,Q9BXF3,O43464,O95831,Q12981 5 +Proteasomal protein catabolic process 0.2700207021854116 0.1228507837356886 0.9022252591929476 1.0 1.0 150 Q96HY6,P46379,Q9UL15,O15294,Q9BZK7,P20618,P51665,Q9GZU8,P28070,Q96A33,Q14145,Q8WU17,Q8N163,P28072,P49721,P51572,Q96PU5,Q92530,O43791,Q13794,Q9UBV2,P28074,Q92575,Q9Y679,Q8IXB1,Q9UJX3 26 +Positive regulation of ossification 0.4845054114733808 0.1217102432725107 0.9031285005953992 1.0 1.0 3 P20020 1 +Positive regulation of synaptic plasticity 0.4751291989664052 0.1196779944783643 0.9047382329131346 1.0 1.0 2 Q9UJX6 1 +Anatomical structure maturation 0.2943752132710798 0.1182284455922946 0.9058866516924676 1.0 1.0 26 Q08J23,Q96JM7,O75503,O75787 4 +Positive regulation of catabolic process 0.2976641254981156 0.117596195651696 0.9063876194610516 1.0 1.0 130 Q96HY6,P46379,P31751,P21796,O15269,O75396,Q9Y5X1,Q9NQT5,Q969T7,Q14145,Q8WU17,O95817,Q07812,O95453,P09601,P51572,Q6ZXV5,Q96PU5,O43847,P18031,Q96B26,P50416,Q92879,Q9BXS4,Q8TBX8,P67809,O60506,Q9P0J0,Q9HBH5 29 +Vascular associated smooth muscle cell proliferation 0.3206407687064496 0.1169033007680917 0.9069366824563564 1.0 1.0 11 P09601 1 +Cell fate specification 0.3463777490297487 0.1165905275196522 0.9071845444724178 1.0 1.0 6 Q9UJX6,P35222,Q14318,Q96KQ7,Q06330 5 +Regulation of lipase activity 0.3286447042979339 0.1164772531238939 0.9072743127565266 1.0 1.0 9 P16435,P50897,P40616 3 +Protein import 0.3202215633149292 0.1146469217944055 0.908724986670085 1.0 1.0 80 O43615,Q8N1F7,Q99595,Q9UI26,O60830,O75381,Q9NS69,Q7Z3B4,P57740,O95831,O14737,Q7Z4Q2,Q15388,P52292,O14925,P60602 16 +Positive regulation of intrinsic apoptotic signaling pathway 0.2944051718278988 0.1145504915131328 0.908801423335019 1.0 1.0 16 Q07812,P23246,P51572,Q07820,Q13794,Q9Y3D6 6 +Intracellular transport 0.3405734925917295 0.1140161743465092 0.909224971781558 1.0 1.0 519 O43615,P00846,Q9Y2D4,Q14108,P46379,Q99595,O14678,O60830,Q9NRW7,P57740,P45880,Q03001,Q9NZJ7,Q9Y584,O94901,O14925,P49458,P24390,Q5W0Z9,O75396,Q9NS69,O43464,O75964,Q15005,O15118,Q8WXH0,O43731,P52292,P62072,O43772,O95817,Q8N4H5,Q07812,O75503,P55786,A4D1P6,O60313,O95429,P18031,Q9Y3D6,Q9Y282,O75844,P43307,Q9BY77,Q86U38,Q9P2W9,Q08J23,Q9P0J0,Q03518,O43681,P07602,P31751,O95831,P27105,Q5BJH7,O14737,O60725,Q9UBX3,Q53H12,Q7Z4Q2,Q8WU17,Q13277,Q9Y3B3,O14653,O75431,Q13794,Q9UBV2,O14976,O75298,Q9Y5M8,P23786,O60499,Q10713,Q9UNK0,Q15070,O43752,P16615,Q00765,Q9BRK0,Q96RT1,P07196,Q8N2H4,Q96PC5,Q9UJS0,Q15363,Q9UGP8,Q9UJZ1,Q9Y5X1,Q15388,P07437,O75381,P50402,P51572,O00203,Q15629,P50416,Q9P260,O95249,O95070,Q9UI26,P06576,Q9Y679,Q6NUQ1,O60749,O15400,Q96RQ1,Q9BSR8,P16260,Q8N1F7,Q5JRA6,P61916,Q4J6C6,Q8NHH9,P60602,Q9BVK6,P83436,P10619,Q7Z3B4,Q5SNT2,P40616 120 +Lung epithelium development 0.3557619343753559 0.1137067495181508 0.9094702618857696 1.0 1.0 5 P09960 1 +Regulation of map kinase activity 0.3061034312034048 0.1136017198165899 0.9095535239626972 1.0 1.0 14 P14174,Q96JB5,P30040,P18031 4 +Response to estrogen 0.3110518809820953 0.1135512118243226 0.909593564422058 1.0 1.0 13 P09601 1 +Dna unwinding involved in dna replication 0.3003328439032535 0.1128864256029052 0.9101205983343346 1.0 1.0 15 Q9BRX5,P33991,Q9BRT9 3 +Negative regulation of interleukin 6 production 0.468023255813966 0.1119981303330964 0.9108248890228268 1.0 1.0 2 P04062 1 +Chondrocyte differentiation involved in endochondral bone morphogenesis 0.4677002583979337 0.1116626172031455 0.911090921053499 1.0 1.0 2 P08133 1 +Phagosome lysosome fusion 0.4765751211631505 0.1113930670761802 0.9113046575192104 1.0 1.0 3 Q9BZG1,Q9NVJ2 2 +Response to light stimulus 0.3006531231143951 0.1100938276346143 0.912334963236012 1.0 1.0 49 Q8N163,P22830,Q9BRK5,P31751,Q96K76 5 +Response to interleukin 6 0.3540252182347155 0.1100060833882142 0.912404550352536 1.0 1.0 5 P35232,P40763,Q13546,Q6PD62 4 +Regulation of ubiquitin dependent protein catabolic process 0.3060844262603488 0.1085311431679534 0.9135743777369116 1.0 1.0 55 Q8N163,Q9H2J4,Q96HY6,P46379,Q9UL15,O15294,Q05086,P51572,Q14145,Q8WU17 10 +Fluid transport 0.4638242894056972 0.1077270636679338 0.9142122007361162 1.0 1.0 2 O43865 1 +Mrna 5 splice site recognition 0.3784744667097629 0.1069519847358914 0.914827071808758 1.0 1.0 4 Q12872,Q07955,O75475 3 +Protein o linked fucosylation 0.4625322997416033 0.1064520817553485 0.915223672522522 1.0 1.0 2 Q9Y2G5 1 +Fucosylation 0.4625322997416033 0.1064520817553485 0.915223672522522 1.0 1.0 2 Q9Y2G5 1 +Intermembrane lipid transfer 0.3415944104278723 0.1044706729832598 0.9167958404734272 1.0 1.0 6 P04114 1 +Farnesyl diphosphate metabolic process 0.4707538394680032 0.1042509336509562 0.9169702149319672 1.0 1.0 3 P37268 1 +Meiotic cell cycle 0.3018413448362537 0.1038688234856301 0.9172734485030204 1.0 1.0 51 Q9UQ84,Q08J23,P46379,Q9BTX1 4 +Positive regulation of type i interferon mediated signaling pathway 0.4697899838449014 0.1031032602127401 0.9178810175401272 1.0 1.0 3 Q9NZI8,Q7Z434 2 +Positive regulation of mapk cascade 0.2856961238165442 0.10284025981344 0.9180897519344606 1.0 1.0 37 Q9Y4G8,P18615,P04899,Q6IAA8,P35222,P23396,P14174,O15344,P30040,Q99623,P46109,P18031,P35232,Q9UMX5,Q13641,O75915 16 +Negative regulation of plasma membrane bounded cell projection assembly 0.3404657625088702 0.1016706506359245 0.9190180987973062 1.0 1.0 6 O94813 1 +Mitochondrial transcription 0.3273723478758736 0.1014365222443024 0.9192039454204284 1.0 1.0 8 Q00059,Q9BSK2,O00411,Q96RR1 4 +Lymphocyte costimulation 0.4681744749595948 0.1012017380971156 0.919390317002037 1.0 1.0 3 P07947,P07948 2 +Cellular response to fatty acid 0.340232858990938 0.1010957031444088 0.9194744889660912 1.0 1.0 6 P01130,P13010,Q15120,P11802,P50416 5 +Cell cycle dna replication 0.2945706458386306 0.101058914164679 0.919503692761267 1.0 1.0 19 O75844,P33991 2 +Negative regulation of hormone metabolic process 0.4563953488372129 0.1006432600946329 0.9198336544395408 1.0 1.0 2 P05023 1 +Organelle transport along microtubule 0.2913416470432411 0.0994092642946256 0.9208133273576048 1.0 1.0 26 O75381,P07196,O00203,Q8WXH0,O94901,Q5SNT2 6 +Cd4 positive or cd8 positive alpha beta t cell lineage commitment 0.4541343669250663 0.098604540878869 0.9214522644948224 1.0 1.0 2 P40763 1 +Positive t cell selection 0.4541343669250663 0.098604540878869 0.9214522644948224 1.0 1.0 2 P40763 1 +T helper cell lineage commitment 0.4541343669250663 0.098604540878869 0.9214522644948224 1.0 1.0 2 P40763 1 +Cellular response to leucine 0.4541343669250618 0.0986045408788651 0.9214522644948256 1.0 1.0 2 Q9P2J5 1 +Establishment of protein localization to plasma membrane 0.2943645904968342 0.0967406801375988 0.9229323332433704 1.0 1.0 21 P98194,Q8N2H4 2 +Regulation of generation of precursor metabolites and energy 0.2847393221724038 0.0957762768571706 0.9236982590519762 1.0 1.0 37 P14406,P31751,P14635,O75746,Q9BSK2,Q9NQ88 6 +Response to toxic substance 0.3033259588994708 0.093511629209075 0.9254971114046864 1.0 1.0 54 P08183,P07099,P78417,Q15165 4 +Regulation of leukocyte mediated immunity 0.2887440724157119 0.0925096916353774 0.9262930914305694 1.0 1.0 27 O15400,P02786,Q5RKV6,P09601,Q9NQT5,Q9NUQ9 6 +Rna surveillance 0.3133271087692337 0.0899625505258751 0.928316974466294 1.0 1.0 11 Q5RKV6,Q9NQT5,Q96B26 3 +Long chain fatty acid biosynthetic process 0.4549273021001632 0.0866380418722308 0.930959226533109 1.0 1.0 3 O00154,Q96PU8 2 +Positive regulation of phosphatase activity 0.4542810985460365 0.0859738169355183 0.9314872312011232 1.0 1.0 3 Q15257,P08238 2 +Positive regulation of phosphoprotein phosphatase activity 0.4542810985460365 0.0859738169355183 0.9314872312011232 1.0 1.0 3 Q15257,P08238 2 +Cochlea development 0.3420627222761047 0.085883346376521 0.9315591502574754 1.0 1.0 5 P33993,P49736,P43034,Q13308 4 +Pigmentation 0.2914609486142544 0.0850562714535311 0.9322166545956284 1.0 1.0 19 Q04656,Q07812,Q9H267,Q13561,O75787,O00203,Q15907 7 +Regulation of response to interferon gamma 0.4529886914377983 0.0846580485368991 0.9325332486008892 1.0 1.0 3 Q15648,P08238 2 +Regulation of neuroblast proliferation 0.3642533936651603 0.0844155890154823 0.9327260132832288 1.0 1.0 4 O60341,P35222,P35221 3 +Regulation of tissue remodeling 0.3642533936651604 0.0844155890154823 0.9327260132832288 1.0 1.0 4 P41240,P17252,P02786 3 +Cellular response to cold 0.4331395348837196 0.0821418719713808 0.9345338965890332 1.0 1.0 2 Q13217 1 +Negative regulation of glial cell differentiation 0.4315245478036138 0.0810507454582505 0.935401596178002 1.0 1.0 2 P35222 1 +Regulation of potassium ion transmembrane transporter activity 0.3174415333763892 0.0806260761640281 0.9357393279310446 1.0 1.0 9 Q96PU5,P50570 2 +Regulation of t circle formation 0.4305555555555552 0.0804074485668168 0.9359132029890572 1.0 1.0 2 Q15554 1 +Regulation of atp biosynthetic process 0.3314509338324657 0.0801354775267729 0.9361295064818208 1.0 1.0 6 P00403 1 +Positive regulation of protein localization to cell periphery 0.290003519333443 0.0776664780614558 0.938093360162716 1.0 1.0 19 P98194 1 +Multi multicellular organism process 0.2902599844077744 0.0750757077322714 0.940154475687843 1.0 1.0 22 Q9UIQ6,P41440 2 +Mitochondrial adp transmembrane transport 0.4423263327948284 0.0744381637946324 0.9406617427056204 1.0 1.0 3 P05141,P12236 2 +Trna modification 0.2901555010196744 0.0741654021633851 0.9408787750804016 1.0 1.0 21 Q9NX74,Q5JTZ9,Q7L0Y3,Q08J23,Q5VV42,O75648,Q9H9T3 7 +Regulation of canonical wnt signaling pathway 0.2775006262601467 0.0730251760907344 0.9417860833686986 1.0 1.0 34 Q8N163,P50402,Q9BZK7,Q96K76,Q13641 5 +Positive regulation of nuclease activity 0.4402685973816294 0.0725938533606824 0.9421293181238636 1.0 1.0 3 P12004 1 +Membrane invagination 0.3007765244562304 0.0714988440218005 0.9430007445422056 1.0 1.0 13 P51790,Q9Y5X1 2 +Negative regulation of circadian rhythm 0.4127906976744147 0.070049021121152 0.9441546422202336 1.0 1.0 2 P23246 1 +Response to molecule of bacterial origin 0.2770667502634856 0.0699342942844775 0.944245957049713 1.0 1.0 34 P08670,P14174,Q9NUQ9,Q8WTV0 4 +Cardioblast differentiation 0.4111757105943143 0.0692349362327695 0.9448026147242156 1.0 1.0 2 Q06330 1 +Intracellular mrna localization 0.411175710594312 0.0692349362327684 0.9448026147242166 1.0 1.0 2 Q99729 1 +Negative regulation of mrna metabolic process 0.2920392065188433 0.0684984062423016 0.9453888887323624 1.0 1.0 46 P26368,O75494,Q99729,Q14011,P07910,Q5VTR2,P50750,Q92804,Q15717,P16989,O00422,P61978,P38159,P98175,P18615,Q16629,P67809,P35637,O75150,O60506 20 +Somatic stem cell population maintenance 0.4092377260981902 0.068284374024946 0.9455592628151336 1.0 1.0 2 Q06330 1 +T cell differentiation 0.2883267498035998 0.0662200596677586 0.947202626520406 1.0 1.0 23 O96005,O00203,P24390,P0CG08 4 +Phosphorylation of rna polymerase ii c terminal domain 0.4326332794830377 0.0661018437270929 0.9472967429820158 1.0 1.0 3 Q8WUA2,P50750 2 +Negative regulation of low density lipoprotein particle clearance 0.4316639741518587 0.0653166121031801 0.9479219160417782 1.0 1.0 3 P41240,Q92945 2 +Cellular response to amyloid beta 0.3299377913860005 0.0638824631791268 0.9490638161093108 1.0 1.0 5 P33527,Q9UNH7 2 +Response to amyloid beta 0.3299377913860005 0.0638824631791268 0.9490638161093108 1.0 1.0 5 P33527,Q9UNH7 2 +Regulation of humoral immune response 0.4271405492730132 0.0617656146832228 0.9507494866903394 1.0 1.0 3 P35232,Q99623 2 +Regulation of complement activation 0.4271405492730132 0.0617656146832228 0.9507494866903394 1.0 1.0 3 P35232,Q99623 2 +Complement activation 0.4271405492730132 0.0617656146832228 0.9507494866903394 1.0 1.0 3 P35232,Q99623 2 +Suppression of viral release by host 0.4268174474959598 0.0615190463887342 0.9509458463092136 1.0 1.0 3 Q14258,P14373 2 +Regulation of b cell activation 0.2829574781744804 0.0603174449657812 0.951902808168606 1.0 1.0 16 Q5RKV6,P14174,Q96IZ0,P02786 4 +Negative regulation of mitochondrial membrane permeability 0.3875968992248062 0.0594682428218296 0.952579159252122 1.0 1.0 2 P42765 1 +Negative regulation of membrane permeability 0.3875968992248062 0.0594682428218296 0.952579159252122 1.0 1.0 2 P42765 1 +Negative regulation of chromatin binding 0.3853359173126595 0.058720998737804 0.9531743336219852 1.0 1.0 2 Q7Z5K2 1 +Regulation of nuclease activity 0.3094852703140088 0.0568197082443315 0.9546888143903608 1.0 1.0 9 P61221,P12004,P55061,P23396,P26583,Q15554,O00273,P06748 8 +Serotonin metabolic process 0.3785529715762276 0.0566544442547427 0.9548204639091328 1.0 1.0 2 Q04656 1 +Response to interleukin 7 0.3094012982426299 0.0565759892782366 0.954882961681768 1.0 1.0 9 P06576 1 +Positive regulation of neuroblast proliferation 0.3775839793281632 0.0563798043798796 0.9550392451313224 1.0 1.0 2 P35222 1 +Negative regulation of alpha beta t cell proliferation 0.3753229974160211 0.055758153550373 0.9555344716809406 1.0 1.0 2 Q96J02 1 +Interleukin 17 production 0.375322997416016 0.0557581535503716 0.9555344716809416 1.0 1.0 2 P35232 1 +Negative regulation of ossification 0.3746770025839796 0.0555853876422129 0.9556721054787922 1.0 1.0 2 Q06330 1 +Visual behavior 0.3425985778926974 0.0555673979827818 0.9556864370000676 1.0 1.0 4 Q9NPQ8,P05556,Q00535 3 +Linoleic acid metabolic process 0.4184168012924052 0.0554312388145888 0.9557949091128808 1.0 1.0 3 P28161,Q9NP80 2 +Relaxation of cardiac muscle 0.4177705977382916 0.0549882388295117 0.956147833671076 1.0 1.0 3 P28161,P05023 2 +Sodium ion export across plasma membrane 0.4177705977382899 0.0549882388295103 0.9561478336710773 1.0 1.0 3 P54709,P05023 2 +Negative regulation of cell death 0.2643597389617157 0.0536282941894941 0.9572313134397978 1.0 1.0 201 P46379,Q9UL15,P07196,Q9HCL2,P31751,P21796,P45880,Q96K76,Q12981,P04899,P50897,Q15392,Q86XL3,O15118,Q9NQ88,Q8N163,Q8NDZ4,P09601,Q9UMX5,Q96TA2,Q9P0J0,P14174 22 +Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia 0.364018087855298 0.0530277038172766 0.9577098343071035 1.0 1.0 2 Q06330 1 +Regulation of transcription from rna polymerase ii promoter in response to hypoxia 0.364018087855298 0.0530277038172766 0.9577098343071035 1.0 1.0 2 Q06330 1 +Negative regulation of neuroblast proliferation 0.3640180878552921 0.0530277038172752 0.9577098343071048 1.0 1.0 2 P35221 1 +B cell homeostasis 0.3230743744417238 0.0525196297468583 0.9581146546421606 1.0 1.0 5 P14174 1 +Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.3594961240310032 0.05209772461297 0.9584508260017232 1.0 1.0 2 P23396 1 +Establishment of mitochondrion localization 0.3095068898308296 0.05097268037194 0.959347290144582 1.0 1.0 8 P07196 1 +Negative regulation of mrna catabolic process 0.2849687960350559 0.0505705518721544 0.9596677289908512 1.0 1.0 24 P98175,P16989,Q99729,Q14011,P67809,Q92804,P07910,P11940,Q15717,P35637,O60506 11 +Regulation of spontaneous synaptic transmission 0.3459302325581386 0.0497889457771563 0.9602905757506937 1.0 1.0 2 P55011 1 +Spontaneous synaptic transmission 0.3459302325581386 0.0497889457771563 0.9602905757506937 1.0 1.0 2 P55011 1 +Regulation of leukocyte migration 0.2847720025127364 0.0494818858975748 0.960535272474623 1.0 1.0 24 Q5JRA6,Q4KMQ2,P09601,O94813,Q08722,P14174 6 +Regulation of synapse maturation 0.3430232558139526 0.0493782399959874 0.9606178689722952 1.0 1.0 2 Q9UJX6 1 +Arf protein signal transduction 0.4087237479806159 0.0491515311364916 0.9607985370942352 1.0 1.0 3 Q8N6T3,Q92538 2 +Negative regulation of tumor necrosis factor superfamily cytokine production 0.408530752890276 0.0490342845454488 0.960891973674725 1.0 1.0 3 O43823 1 +Regulation of dna dependent dna replication 0.2852139083328371 0.0484535736192743 0.9613547638359012 1.0 1.0 21 Q9BRX5,Q9UJZ1,O75844,Q9BRT9 4 +Lactate metabolic process 0.316733252800339 0.0481987528028877 0.9615578441532906 1.0 1.0 6 Q9NQ88 1 +Cellular monovalent inorganic anion homeostasis 0.3330103359173131 0.0481590852130633 0.9615894575987788 1.0 1.0 2 P55011 1 +Cellular anion homeostasis 0.3330103359173131 0.0481590852130633 0.9615894575987788 1.0 1.0 2 P55011 1 +Regulation of glucocorticoid metabolic process 0.3278423772609762 0.0476362994871025 0.9620061020486284 1.0 1.0 2 P05023 1 +Regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.3031088082901534 0.0471083437315036 0.96242687738622 1.0 1.0 10 Q9HBM6,P61254,O60341,P61978,P04637,P62081,P14174,P63241,Q8N2F6 9 +Regulation of tolerance induction 0.3087855297157579 0.0462131496937796 0.9631403617330448 1.0 1.0 2 Q96J02 1 +Vascular endothelial cell proliferation 0.3087855297157543 0.0462131496937793 0.963140361733045 1.0 1.0 2 P40763 1 +Positive regulation of vascular endothelial cell proliferation 0.3087855297157543 0.0462131496937793 0.963140361733045 1.0 1.0 2 P40763 1 +Positive regulation of neuron apoptotic process 0.2969510198497357 0.0454385021862607 0.9637577923593474 1.0 1.0 12 Q15375,O95831,Q07812 3 +Regulation of lipoprotein metabolic process 0.3184610410604541 0.0453214999883188 0.9638510505318056 1.0 1.0 5 Q5HYI8,P06756,Q15042,P04062 4 +Regulation of endoplasmic reticulum tubular network organization 0.3184610410604544 0.0453214999883188 0.9638510505318056 1.0 1.0 5 Q15042,P57088,Q15041,Q9C0E8 4 +Peroxisome proliferator activated receptor signaling pathway 0.3993537964458821 0.0437947282581996 0.9650680292948476 1.0 1.0 3 O43707,Q15648 2 +Constitutive secretory pathway 0.3987075928917649 0.0434499402476906 0.9653428687023222 1.0 1.0 3 Q8TBQ9,Q15907 2 +Development of secondary female sexual characteristics 0.3964458804523376 0.042267441980449 0.9662854996163748 1.0 1.0 3 Q15648,Q99623 2 +Peroxisome organization 0.296029574088308 0.042205400353662 0.966334957538456 1.0 1.0 12 O14678,O75381,Q9Y3D6,O14734 4 +Renal water homeostasis 0.3935379644588081 0.0408016776901974 0.9674540018709096 1.0 1.0 3 P17252,O76024 2 +Glucocorticoid metabolic process 0.3280542986425359 0.0397426742518556 0.968298279402128 1.0 1.0 4 P05023,P51608,Q04917 3 +Post chaperonin tubulin folding pathway 0.3254686489980627 0.0372136929422991 0.9703146207861107 1.0 1.0 4 O75347,Q9BTW9,O75695 3 +Cellular metabolic compound salvage 0.3022345314293906 0.0363665296708397 0.9709901019699404 1.0 1.0 9 Q13126 1 +Deoxyribose phosphate catabolic process 0.3122971143300768 0.036328565591203 0.9710203729201944 1.0 1.0 7 Q9H773 1 +Negative regulation of glycolytic process 0.383777462952885 0.0363124773357506 0.9710332010267462 1.0 1.0 3 Q9NQ88 1 +Regulation of myelination 0.3032362459546998 0.0348661809132735 0.9721864479293564 1.0 1.0 8 P35222,Q7L576,O75312,P53634,O75746,P42345,Q13614 7 +Protein polymerization 0.3056945990961411 0.0342915505399386 0.9726446626010308 1.0 1.0 67 P07196,Q16625,Q9Y5X1,O94813,P45880,Q9NUQ9,Q9UEY8,Q9UQB8 8 +Golgi disassembly 0.3223070422498391 0.0342342172257883 0.9726903811238068 1.0 1.0 4 Q13190,Q92538 2 +Primary amino compound metabolic process 0.3786752827140542 0.0342164101774912 0.9727045807737436 1.0 1.0 3 Q04656,Q9NZC3 2 +Positive regulation of cell size 0.3777059773828738 0.033836710862717 0.973007361661298 1.0 1.0 3 Q04656,P08238 2 +Positive regulation of epithelial to mesenchymal transition 0.3103782735208482 0.033551642531718 0.9732346842046128 1.0 1.0 5 P35222,P42345,Q96AC1,Q92769 4 +Vascular associated smooth muscle cell migration 0.3102959553624762 0.0334372297608916 0.9733259211952552 1.0 1.0 5 Q04656,Q14344 2 +Chemokine c c motif ligand 5 production 0.3754442649434557 0.032973112207836 0.9736960293281254 1.0 1.0 3 Q7Z434,O00571 2 +Regulation of epithelial to mesenchymal transition 0.3105791006146805 0.0324978613457119 0.9740750215292326 1.0 1.0 7 Q96AC1,P35222,Q7Z460,Q9Y2G5,Q92769,P42345 6 +Thioester metabolic process 0.2835647288001927 0.0319375768332942 0.9745218319348712 1.0 1.0 43 P50897,Q9UMR5,Q9HCL2 3 +Negative regulation of metaphase anaphase transition of cell cycle 0.2864409683503274 0.0318602904426712 0.9745834661869968 1.0 1.0 14 P50748 1 +Regulation of deoxyribonuclease activity 0.3090850307145096 0.0317667862081421 0.9746580340274194 1.0 1.0 5 O00273,P23396,P12004,P06748 4 +3 utr mediated mrna stabilization 0.3018943005609764 0.031530385928576 0.9748465597197916 1.0 1.0 8 P98175,P07910,P16989 3 +Negative regulation of autophagosome assembly 0.3712439418416779 0.0314503213874384 0.9749104103146886 1.0 1.0 3 Q8WVM8,O75396 2 +Peptidyl lysine hydroxylation 0.3077580365185405 0.0307098858178618 0.9755009071396076 1.0 1.0 6 Q92791,Q9H267 2 +Regulation of protein lipidation 0.3183581124757616 0.030684071053639 0.9755214946392892 1.0 1.0 4 Q5HYI8,Q15042,P04062 3 +Interleukin 10 production 0.3180625990303967 0.0304259434568749 0.9757273545441854 1.0 1.0 4 Q08722 1 +Monovalent inorganic anion homeostasis 0.3673973969928963 0.0301449782698763 0.9759514295428924 1.0 1.0 3 Q9BXP2 1 +Nadp metabolic process 0.2761500339626931 0.0301333700584441 0.9759606873498614 1.0 1.0 16 Q13423,Q9NQ88,Q7Z4W1,P23368 4 +Interleukin 6 mediated signaling pathway 0.3660743134087264 0.0297150470173931 0.9762943114366468 1.0 1.0 3 P40763,Q6PD62 2 +Nuclear body organization 0.3167420814479661 0.0292851778947669 0.9766371481596904 1.0 1.0 4 P78362,Q15637,O75312 3 +Negative regulation of helicase activity 0.3641357027463653 0.0291022749586087 0.9767830214131608 1.0 1.0 3 P33993,P49736 2 +Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus 0.3641357027463652 0.0291022749586084 0.976783021413161 1.0 1.0 3 Q06330,Q9NXV6 2 +Actin filament polymerization 0.2752413600083551 0.0278439038270687 0.9777866493331004 1.0 1.0 37 Q9Y5X1,O94813,Q9NUQ9,Q9UEY8,Q9UQB8 5 +Regulation of metallopeptidase activity 0.3582988260074419 0.0273764459674702 0.9781594846014012 1.0 1.0 3 Q96HY6 1 +Cellular response to leucine starvation 0.3544426494345726 0.0263300838826395 0.9789940597564162 1.0 1.0 3 P42345,Q9P2J5 2 +Negative regulation of endoplasmic reticulum unfolded protein response 0.3034521994113439 0.0243043687757053 0.9806098283825596 1.0 1.0 5 Q96HY6,P18031 2 +Negative regulation of anoikis 0.3460420032310218 0.0242908765693391 0.9806205904284226 1.0 1.0 3 Q07820,Q9Y3E5 2 +Positive regulation of cellular response to transforming growth factor beta stimulus 0.310277957336783 0.0239951790536259 0.9808564541591922 1.0 1.0 4 Q13573,O60315,P08238 3 +Sensory perception of pain 0.3424878836833622 0.0235208668027635 0.98123479378684 1.0 1.0 3 Q9BPW8,Q00535 2 +Negative regulation of response to dna damage stimulus 0.2799467145336632 0.0232647907716341 0.9814390570013538 1.0 1.0 24 Q8N163,Q96K76 2 +Dendritic cell chemotaxis 0.3089851325145466 0.0229946515242318 0.9816545392879704 1.0 1.0 4 Q4KMQ2,P27797,Q07021 3 +Regulation of receptor internalization 0.2948434322886397 0.0226543963034395 0.9819259529671708 1.0 1.0 10 P41440 1 +Regulation of protein complex stability 0.3083387201034281 0.0225014340862863 0.982047968055198 1.0 1.0 4 Q9BQ95,Q969V3,Q7Z392 3 +Vesicle cargo loading 0.2873398487805486 0.0209697549917734 0.9832697823887364 1.0 1.0 13 Q15363,Q96PC5 2 +Regulation of alcohol biosynthetic process 0.305080481133256 0.020633538473081 0.9835379863234852 1.0 1.0 7 P16435 1 +Regulation of cholesterol biosynthetic process 0.305080481133256 0.020633538473081 0.9835379863234852 1.0 1.0 7 P16435 1 +Positive regulation of jun kinase activity 0.3232451976033605 0.02018383819719 0.9838967205107992 1.0 1.0 3 P18031 1 +Positive regulation of mirna mediated gene silencing by inhibition of translation 0.3205169628432994 0.0198110506233447 0.9841941024915656 1.0 1.0 3 P26196,P40763 2 +Positive regulation of translation in response to stress 0.3205169628432964 0.0198110506233441 0.984194102491566 1.0 1.0 3 Q13217,O00571 2 +Positive regulation of translation in response to endoplasmic reticulum stress 0.3205169628432964 0.0198110506233441 0.984194102491566 1.0 1.0 3 Q13217,O00571 2 +Pathway restricted smad protein phosphorylation 0.3101777059773831 0.0185887373967467 0.9851691875405872 1.0 1.0 3 Q13526,P67870 2 +Regulation of endodeoxyribonuclease activity 0.3088852988691462 0.0184554917568603 0.9852754839443184 1.0 1.0 3 P23396,P06748 2 +Tolerance induction 0.3088852988691471 0.0184554917568603 0.9852754839443184 1.0 1.0 3 Q96J02,P07948 2 +Mesonephric tubule morphogenesis 0.3088225831097646 0.0184491289922985 0.9852805598317138 1.0 1.0 3 Q13418 1 +Regulation of osteoclast differentiation 0.3017770597738304 0.0177921568654985 0.985804661685638 1.0 1.0 3 P35222,P42345 2 +Response to leucine 0.2969305331179341 0.0174020943260819 0.9861158383785784 1.0 1.0 3 P42345,Q9P2J5 2 +Regulation of production of molecular mediator of immune response 0.2788099522487351 0.0172245075768515 0.986257510869023 1.0 1.0 24 P02786,Q5RKV6,P09601,Q9NQT5,P14174 5 +Cell fate determination 0.2929581395507149 0.0171163688125114 0.9863437804013728 1.0 1.0 3 Q07820 1 +Feeding behavior 0.2998390427819636 0.016530965862807 0.9868107982740616 1.0 1.0 6 Q9GZP9,P50416 2 +Nuclear membrane organization 0.2790359074480326 0.0164965025371927 0.9868382922803712 1.0 1.0 22 Q86XL3 1 +Regulation of synapse assembly 0.2945483687400689 0.0160112339449046 0.9872254294522822 1.0 1.0 9 Q15375,Q13641,Q9Y4F1 3 +Steroid esterification 0.2701130856219732 0.0159552876889061 0.987270062404738 1.0 1.0 3 P35610,Q6IAA8 2 +Ubiquitin recycling 0.2436187399030741 0.0153084485463298 0.9877861023085326 1.0 1.0 3 P61086,Q16763 2 +Production of molecular mediator of immune response 0.2659315183054987 0.013278929374798 0.9894052586305018 1.0 1.0 32 P09601,Q9UQ84 2 +Cellular extravasation 0.2942127384416356 0.0131402884359995 0.9895158684441931 1.0 1.0 5 P46109,P05556,Q9Y624,Q08722 4 +Rna destabilization 0.2700664574008953 0.0115614512837707 0.9907755020227308 1.0 1.0 35 O95453,P67809,O60506,Q96B26,Q9NQT5,Q969T7,Q9HBH5,Q92879 8 +Dna methylation dependent heterochromatin assembly 0.2868968690623313 0.0114420723125022 0.9908707463605636 1.0 1.0 12 Q15047,Q8NEY8,Q96JM7 3 +Neuromuscular junction development 0.2964306987344109 0.0107875820377021 0.9913929217810922 1.0 1.0 6 Q12955,Q14696 2 +Kidney epithelium development 0.2891409639051776 0.0102923232198098 0.991788059192816 1.0 1.0 11 Q15375,O94813 2 +Canonical wnt signaling pathway 0.2712685701404073 0.0101172697361858 0.9919277243921284 1.0 1.0 36 Q8N163,P50402,Q9BZK7,Q96K76,Q13641 5 +Anoikis 0.28839314581312 0.0067749126666558 0.9945944431345262 1.0 1.0 5 Q07820,P05556,P42345,Q9Y3E5 4 +Diencephalon development 0.2970665482682925 0.0044262332155263 0.9964683883864413 1.0 1.0 7 O14949 1 +Regulation of actin nucleation 0.2773574782852289 0.0039146881671673 0.9968765387287896 1.0 1.0 4 P53367 1 +Scarna localization to cajal body 0.272786037491922 0.0019225643893986 0.9984660165015482 1.0 1.0 4 P50991,P78371,P17987 3 +Interleukin 12 production 0.2711700064641267 0.0012587841239553 0.9989956358473544 1.0 1.0 4 P09429,Q08722,Q07021 3 +Protein hydroxylation 0.2816537295269988 0.0012011498070216 0.999041621344218 1.0 1.0 13 Q92791,O75718,Q32P28 3 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..dd20254d00c6460ad179d96bcdfd8d87e7b8dc41 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activation of store operated calcium channel activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Acylglycerol transport", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine catabolic process", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp metabolic process", "Amp salvage", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Arterial endothelial cell differentiation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Bile acid signaling pathway", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into cytosol", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in cardiac muscle cell fate commitment", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac cell fate commitment", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell fate commitment", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell myoblast differentiation", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine secretion", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide 1 phosphate transport", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Choline transport", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Commissural neuron axon guidance", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion import", "Copper ion transmembrane transport", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid receptor signaling pathway", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial skeletal system development", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytolysis by host of symbiont cells", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine secretion", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal aorta development", "Dorsal aorta morphogenesis", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Elastic fiber assembly", "Elastin metabolic process", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardial cushion development", "Endocardial cushion formation", "Endocardial cushion morphogenesis", "Endocardium development", "Endocardium morphogenesis", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil mediated immunity", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial to mesenchymal transition involved in endocardial cushion formation", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of left right asymmetry", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat pad development", "Fat soluble vitamin biosynthetic process", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated inhibitory signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Heat generation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Heparin biosynthetic process", "Heparin metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "Hexose phosphate transport", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k119 monoubiquitination", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus development", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune effector process", "Immune response", "Immune response inhibiting cell surface receptor signaling pathway", "Immune response inhibiting signal transduction", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Inhibitory postsynaptic potential", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell fate commitment", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Iodide transport", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein particle remodeling", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteinizing hormone secretion", "Luteolysis", "Lymph vessel development", "Lymphatic endothelial cell differentiation", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage differentiation", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Mast cell proliferation", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Melanosome assembly", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane fusion involved in viral entry into host cell", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Menaquinone metabolic process", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell fate commitment", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myoblast proliferation", "Myofibroblast differentiation", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immune response to tumor cell", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of astrocyte activation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of camp mediated signaling", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of catecholamine secretion", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular amine metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular response to vascular endothelial growth factor stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of ceramide biosynthetic process", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of dopamine secretion", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of g0 to g1 transition", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of histone acetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein metabolic process", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage activation", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage derived foam cell differentiation", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microglial cell activation", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuroinflammatory response", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl cysteine s nitrosylation", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sphingolipid biosynthetic process", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell differentiation in thymus", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor 2 signaling pathway", "Negative regulation of toll like receptor 4 signaling pathway", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nitrogen utilization", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Norepinephrine metabolic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation cycle", "Ovulation cycle process", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parathyroid gland development", "Paraxial mesoderm development", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification process", "Penetration of zona pellucida", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl l cysteine s palmitoylation", "Peptidyl lysine acetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericardium development", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine acyl chain remodeling", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyamine transmembrane transport", "Polyamine transport", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic process involved in development", "Positive regulation of apoptotic process involved in morphogenesis", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of b cell receptor signaling pathway", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell proliferation involved in heart morphogenesis", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of complement activation", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental pigmentation", "Positive regulation of developmental process", "Positive regulation of digestive system process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of enamel mineralization", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of heat generation", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of inhibitory postsynaptic potential", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage derived foam cell differentiation", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic nuclear division", "Positive regulation of melanocyte differentiation", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myoblast proliferation", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immune response to tumor cell", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of store operated calcium channel activity", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tooth mineralization", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of uterine smooth muscle contraction", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor receptor signaling pathway", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein palmitoylation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adiponectin secretion", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte activation", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid secretion", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of development heterochronic", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of enamel mineralization", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate secretion", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of heat generation", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intestinal lipid absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage derived foam cell differentiation", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic nuclear division", "Regulation of melanocyte differentiation", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myoblast proliferation", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immune response to tumor cell", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pattern recognition receptor signaling pathway", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl cysteine s nitrosylation", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigment cell differentiation", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic cytosolic calcium ion concentration", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rab protein signal transduction", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle cell proliferation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of store operated calcium entry", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell apoptotic process", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 2 signaling pathway", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription from rna polymerase ii promoter involved in heart development", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell proliferation", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wnt signaling pathway involved in heart development", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to herbicide", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lithium ion", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cell programmed cell death", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Sebaceous gland development", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary heart field specification", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of bitter taste", "Sensory perception of chemical stimulus", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory perception of sweet taste", "Sensory perception of taste", "Sensory system development", "Septum primum development", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermidine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Store operated calcium entry", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Tolerance induction to self antigen", "Toll like receptor 2 signaling pathway", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by trans synaptic complex", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription factor catabolic process", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type b pancreatic cell proliferation", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Udp n acetylglucosamine transmembrane transport", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urea cycle", "Urea metabolic process", "Urinary bladder smooth muscle contraction", "Urinary tract smooth muscle contraction", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APOB", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C2CD5", "C3orf58", "C5orf51", "CAAP1", "CAB39", "CACYBP", "CAD", "CALR", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPI", "CENPP", "CENPQ", "CENPU", "CENPV", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COG2", "COG5", "COG6", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLK", "DOLPP1", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAM162A", "FAM192A", "FAM207A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMC1", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "M6PR", "MACF1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS27", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NEPRO", "NES", "NFATC2IP", "NFS1", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "ROMO1", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RSRC1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35A4", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPNS1", "SPOP", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM29", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF3", "TM9SF4", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM33", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPYL1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBIAD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "UROD", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YIF1A", "YIF1B", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZCCHC17", "ZCCHC3", "ZCCHC8", "ZDHHC20", "ZEB2", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF148", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["AARS2", "AASDHPPT", "ABCB1", "ABCB7", "ABCB8", "ABCC1", "ABCD4", "ABCE1", "ABHD10", "ACAA2", "ACADVL", "ACAT2", "ACBD3", "ACOT7", "ACOT8", "ACOX3", "ACP2", "ACP6", "ACTN4", "ADAR", "ADD1", "ADD3", "ADI1", "ADPGK", "AFDN", "AGK", "AGPAT1", "AHCYL1", "AIFM1", "AIMP2", "AKAP1", "AKAP8", "AKT2", "ALDH1B1", "ALDH3A2", "ALG1", "ALG12", "ALG2", "ALYREF", "AMOT", "ANAPC2", "ANAPC7", "ANK3", "ANKLE2", "ANO6", "ANXA6", "AP3B1", "APOB", "ARFGAP1", "ARFIP1", "ARG2", "ARHGEF2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC1", "ARMC10", "ASAH1", "ASNA1", "ATAD3A", "ATAD3B", "ATL2", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5L", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP7A", "ATP7B", "ATXN10", "AUP1", "B4GAT1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BASP1", "BAX", "BCAP31", "BCL2L13", "BNIP1", "BSG", "BUB1B", "C12orf73", "C19orf70", "C1QBP", "C3orf58", "CALR", "CASK", "CCAR2", "CCDC134", "CCDC47", "CCNB1", "CCT2", "CCT4", "CD47", "CDCA5", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2AIP", "CECR2", "CELF1", "CENPP", "CEP44", "CEPT1", "CERS2", "CETN2", "CHCHD3", "CHST14", "CIRBP", "CKAP2", "CKAP5", "CLASP1", "CLCN3", "CLCN7", "CLN5", "CLPP", "CLPTM1", "CLUH", "CNNM3", "CNNM4", "COA3", "COG5", "COG6", "COG7", "COLEC12", "COMT", "COPS4", "COPS8", "COQ9", "COX15", "COX2", "COX4I1", "COX5A", "COX7A2", "CPD", "CPSF6", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSK", "CSNK2B", "CTNNA1", "CTNNB1", "CTR9", "CTSA", "CTSC", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DCTN1", "DCTN2", "DCTPP1", "DCUN1D5", "DCXR", "DDRGK1", "DDX17", "DDX3X", "DDX6", "DENND4C", "DERL2", "DFFA", "DHCR24", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7B", "DNAAF2", "DNAJC1", "DNAJC10", "DNAJC3", "DNM1L", "DNM2", "DOCK7", "DOHH", "DOLPP1", "DPM1", "DST", "DUS2", "DUSP12", "DUSP9", "ECE1", "ECH1", "ECSIT", "EHD1", "EHMT2", "EIF2AK2", "EIF2B3", "EIF3H", "EIF5", "EIF5A", "ELAVL1", "ELP3", "EMC3", "EMC7", "EMD", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "ERAP1", "ERBIN", "ERGIC2", "ERGIC3", "ERMP1", "ERP29", "ESYT1", "EXO1", "EXOC1", "EXOC6B", "EXOSC3", "EXOSC6", "EXOSC8", "EZR", "F11R", "FAF2", "FAM162A", "FAM192A", "FAM208A", "FAM49B", "FANCD2", "FARP1", "FDFT1", "FDPS", "FECH", "FERMT2", "FIS1", "FKBP8", "FLOT1", "FLOT2", "FOXRED1", "FUCA1", "FUCA2", "FUNDC2", "FUS", "GAA", "GAK", "GALNT7", "GBA", "GBF1", "GCLC", "GDAP1", "GDE1", "GGCX", "GHITM", "GINS3", "GINS4", "GLA", "GLB1", "GLCE", "GLG1", "GLMN", "GNA13", "GNAI2", "GNL3L", "GNS", "GOLT1B", "GOSR1", "GOSR2", "GPAM", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GSR", "GSTM2", "GSTO1", "GTF3C5", "HADH", "HAUS4", "HAUS5", "HDAC2", "HEATR3", "HELLS", "HEXA", "HLA-A", "HLA-C", "HMGB1", "HMGB2", "HMGCL", "HMOX1", "HMOX2", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPK", "HS2ST1", "HSD17B12", "HSP90AB1", "HTRA2", "ICMT", "IGBP1", "IGF2BP1", "ILK", "ILVBL", "INTS13", "IPO11", "IPO9", "IQGAP1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "JAGN1", "KDELR1", "KDELR3", "KDM1A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA1468", "KIF18B", "KIF2C", "KNTC1", "KPNA2", "L3MBTL3", "LAMTOR1", "LARS", "LBR", "LDAH", "LDLR", "LEMD3", "LETM1", "LGALS3BP", "LGMN", "LMAN1", "LMNB1", "LNPEP", "LNPK", "LRRC59", "LRRC8C", "LSM3", "LSM5", "LSS", "LTA4H", "LYN", "MAN1A2", "MAPRE1", "MATR3", "MAVS", "MBNL1", "MBOAT7", "MCL1", "MCM2", "MCM4", "MCM7", "MCU", "ME2", "MECP2", "MED1", "MED12", "MED25", "MESD", "MFSD10", "MFSD8", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICU2", "MID1", "MIF", "MINPP1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPP1", "MPV17L2", "MRC2", "MSH2", "MSMO1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTMR12", "MTMR2", "MTOR", "MTX1", "MTX2", "MYH9", "MYL6", "MYL6B", "NAGLU", "NAMPT", "NANS", "NASP", "NBN", "NCAPD2", "NCAPH", "NCBP2", "NCDN", "NCEH1", "NCLN", "NCOA5", "ND1", "NDC1", "NDUFA11", "NDUFA13", "NDUFA5", "NDUFA7", "NDUFAF1", "NDUFAF2", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFS2", "NDUFS6", "NECAP1", "NECTIN2", "NEDD4L", "NEFL", "NELFE", "NENF", "NFU1", "NIPSNAP1", "NLN", "NNT", "NOP9", "NPC1", "NPC2", "NPEPPS", "NPM1", "NRDC", "NSD2", "NSRP1", "NSUN2", "NT5C2", "NT5C3B", "NTHL1", "NUBPL", "NUCB1", "NUCB2", "NUP107", "NUP133", "NUP35", "NUP54", "NUP88", "NUP93", "OCIAD1", "OCLN", "OGT", "OPA1", "OPA3", "OSBPL6", "OSBPL8", "OXA1L", "P3H1", "P3H4", "P4HB", "PABPC1", "PAFAH1B1", "PARN", "PAWR", "PCBD1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD5", "PDCL3", "PDK3", "PELP1", "PEX11B", "PEX14", "PEX19", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHGDH", "PIGK", "PIN1", "PIP4K2C", "PLA2G15", "PLBD2", "PLIN3", "PLK1", "PLOD3", "PLXNB2", "PMAIP1", "PMPCA", "PNPLA4", "PNPLA6", "PNPLA8", "POFUT2", "POLDIP3", "POLRMT", "PON2", "POP1", "POR", "PPAT", "PPHLN1", "PPIL4", "PPOX", "PPP4R1", "PPT1", "PPT2", "PRAF2", "PRCP", "PREPL", "PRKAR1A", "PRKCA", "PRKCB", "PRKRA", "PSAP", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMC3", "PSMD11", "PSMD7", "PSME2", "PSMF1", "PSMG1", "PTBP2", "PTGES2", "PTK7", "PTPA", "PTPN1", "PTRH2", "PUF60", "PXMP2", "QKI", "RAB10", "RAB11B", "RAB11FIP1", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB3GAP1", "RAB9A", "RABL3", "RAC1", "RACGAP1", "RAD50", "RAPGEF2", "RAVER1", "RBM10", "RBMX", "RBPJ", "RDH13", "RDH14", "RDX", "REEP2", "REEP3", "REEP5", "RETSAT", "RHBDD2", "RIC8A", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RNASET2", "RNF139", "RNF20", "RNF40", "ROMO1", "RP2", "RPL22", "RPL26", "RPL38", "RPRD1A", "RPS3", "RPS7", "RREB1", "RTN2", "RTN3", "RTN4", "SAMHD1", "SAP18", "SCAMP2", "SCARB1", "SCARB2", "SCCPDH", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRIB", "SDF4", "SEC11A", "SEC22B", "SEC63", "SEH1L", "SEL1L", "SETD2", "SETDB1", "SF1", "SFPQ", "SFSWAP", "SFXN2", "SFXN4", "SGPL1", "SHCBP1", "SIGMAR1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC4A7", "SLC7A1", "SLIT2", "SMC4", "SMYD3", "SNW1", "SNX2", "SNX6", "SNX9", "SOAT1", "SORD", "SPAG9", "SPART", "SPCS2", "SPNS1", "SPOP", 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3.2280604409731746 1.23405443481851 0.2890539664507128 0.0005181086307713 0.01497108596825 0.000529997208151 0.0023536569339089 0.0105883475769395 +Cytochrome complex 8 16 2.828755874935311 0.0046729329358921 6.021844660194175 16.08495145631068 1.0267019648816196 0.2321293206617183 2.9315837025395948 1.6175814223208935 1.624269406530766 0.2919563386676546 0.0888202059650672 0.1305522111527444 0.031964215627013 5.657491778833551e-05 5.837517180193655e-06 +Proton transporting two sector atpase complex proton transporting domain 3 12 2.80899494924065 0.0049696426245753 4.053398058252427 10.283980582524272 1.020958321179617 0.2307004649223604 1.8491832641634656 1.1862626633334956 1.3576055733210162 0.273185751006507 0.0001009347750178 6.181069489758794e-07 1.0516191954151127e-05 0.000371706641515 0.0005289198821125 +Snare complex 10 16 2.8087677972754603 0.0049731501845131 6.20873786407767 15.79368932038835 0.8138466711937282 0.3737991711938105 3.1112263618988054 3.010283181947674 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0.298290072492813 9.91705430604444e-12 0.002200987019757 0.0051572349075885 3.0628941740575776e-11 5.113996218804716e-09 +Endoplasmic reticulum golgi intermediate compartment membrane 14 28 2.586307800280598 0.0097010256986069 10.49271844660194 25.839805825242717 1.5441023898993702 0.2324243418613106 5.505729177420246 3.7718384126099376 1.49831312620529 0.2965572765953523 0.0025071770567847 0.0285808600856777 0.0161789595718159 0.000338442961232 5.412109352262341e-05 +Nuclear outer membrane endoplasmic reticulum membrane network 112 341 2.565868743982565 0.0102917764754004 98.3519417475728 305.0218446601942 1.8626549185660248 0.4346737740195964 40.114822105305365 33.029069404441934 2.648813561163414 0.4525721946789457 4.746974560678072e-06 0.0027161550783321 8.836734520717061e-06 3.963661881235446e-09 3.7701772322365535e-18 +Membrane protein complex 91 293 2.5647166050948385 0.0103260105369182 80.6747572815534 286.40291262135923 0.8072324880333213 0.5482017098759524 27.14508025817277 25.65052264389531 1.8803092756171496 0.4277745875695662 7.772924813307447e-05 4.295968576081252e-08 1.3076536770824557e-06 2.7327547832664826e-08 2.780602789554259e-11 +Organelle subcompartment 136 402 2.544287842835352 0.0109500808360774 115.97815533980582 370.4077669902912 1.8466078375892352 0.461199583276842 45.24176702976874 43.040100266333 2.697642340677977 0.4541841641473397 2.010620057158756e-05 0.0055894974974037 4.3500171025582e-05 2.9587115766923644e-08 1.9068708016907276e-20 +Outer mitochondrial membrane protein complex 5 16 2.536143720556205 0.011208072522419 7.157766990291262 15.730582524271844 1.3245491566248977 0.2112996285983387 3.5767402396348245 0.8689557679680192 1.477430451036954 0.2853006280851536 0.0046437067491223 0.0919337377678228 0.0008978593047678 9.22092773458021e-05 0.0002747300414667 +Intrinsic component of golgi membrane 11 16 2.5205476152269046 0.0117172384213362 4.655339805825243 10.08495145631068 1.3178763872097854 0.2129685736028588 2.6046347098798024 1.9780511021437377 1.2704958978874823 0.2699640456705705 0.0355040413058726 1.0 0.0625314301217693 0.0808776862517318 0.0001478156049624 +Golgi apparatus 85 300 2.512549704751326 0.0119862218779578 79.29126213592232 307.80825242718447 1.0941692666231844 0.5225509759640199 24.90716006851961 39.34912971804267 1.7376904428153446 0.4394682295132952 0.0042760312679569 0.1077977925410154 0.0035989414030249 0.0012456745086712 0.0001109829349815 +Respiratory chain complex iv 5 9 2.475874661330652 0.0132910228551494 3.754854368932039 9.74271844660194 0.8119042784517004 0.2590637228606872 2.032646352020888 1.0643473720992946 1.3870085883810457 0.2875864020654643 0.2692522225630656 0.083126337411673 0.1611939416425752 0.0007869115437374 0.0001429815632908 +Intrinsic component of mitochondrial membrane 17 51 2.4736317793842777 0.0133747467879181 20.225728155339805 46.883495145631066 1.6360090381123027 0.2606204408334349 9.735582728924424 5.567853242112672 2.0682718238883013 0.3438986948818692 0.0023826714261619 0.0551599902794207 0.0413282647695778 1.926020230279072e-05 9.448901657314716e-07 +Respirasome 21 47 2.4509350347251067 0.0142485667049077 15.08495145631068 43.37378640776699 1.2524823540042158 0.2922262294299136 6.290312072426717 4.489587979561489 1.7783434517583476 0.3462844006183536 0.0034443276456963 0.0078165677457274 0.0013844952123512 8.587907478336206e-07 1.6606015152181676e-08 +Tim23 mitochondrial import inner membrane translocase complex 2 9 2.4107389101372902 0.0159202406256817 2.2694174757281553 6.342233009708738 1.5180442383336388 0.125307709046494 1.369833329272529 0.8106469094037756 1.2674744491900518 0.2021471972412396 0.0007534171574726 0.0012105019492812 0.0001384716540127 0.0020064706347618 0.0013781701696679 +Copi coated vesicle 5 14 2.4019377536632547 0.0163084832381528 3.366504854368932 13.565533980582524 0.927757948703832 0.3021632050419245 1.9356503178232003 1.3008870969982682 1.2180478421179144 0.2957691490409697 0.0003348720906127 0.0040679264544396 3.5959740301631905e-05 9.22092773458021e-05 0.0002747300414667 +Copi coated vesicle membrane 5 13 2.3410393539361776 0.019230139987969 2.9611650485436893 12.451456310679612 0.9351146201256926 0.2894293018559171 1.7580457491925867 1.2208038158644114 1.2401568068418547 0.2855671555488221 0.0001327727267659 0.0026008925831016 1.391730242568295e-05 2.812625820330817e-05 6.703246650942136e-05 +Proton transporting atp synthase complex coupling factor f o 1 8 2.328141245498275 0.0199046048020048 2.388349514563106 6.79126213592233 0.5842994650422648 0.284211882186535 1.5103719705721683 0.8950355849210965 1.3255228108854136 0.2674401609228611 0.0121723982982892 0.0009934566258862 0.0039921150854813 0.0231366382468947 0.0817606313480972 +Lipid droplet 8 33 2.323239956632975 0.0201662653793741 7.313106796116505 30.72087378640777 0.9597061621709796 0.3916106255858687 3.663189105886808 2.181620314734523 1.1934081113966928 0.3497541884861006 0.0055336707658233 0.0399341953324298 0.1345193233748266 0.0216033331890521 0.0043720646017646 +Golgi associated vesicle membrane 5 18 2.269922921238123 0.0232122601234752 4.201456310679611 19.589805825242717 0.79417597045559 0.3511132904952779 2.457541951272857 2.384047500904294 1.2111660039755976 0.3110721945776767 0.0048303145699814 0.0157111699130222 0.0005845317815958 0.0026376358858749 0.0119603409362114 +Rough endoplasmic reticulum membrane 4 14 2.18222147276759 0.0290931912816023 4.004854368932039 15.45388349514563 0.227662863775847 0.4950170648505519 2.251208031291381 1.6488623515587295 0.9767806743602098 0.3048224995989578 0.063811929472465 0.0058373227860703 0.0224191931510111 0.0195244436529747 0.0052134507581354 +Endocytic vesicle membrane 5 43 2.1316311912527444 0.0330371774887408 11.41019417475728 40.75728155339806 0.6528171904926832 0.3529092384633215 4.825015011915381 4.780047567333447 1.5638167276319088 0.3380752375601685 0.0134264389898591 0.0020643275657996 0.0047886998768676 0.0564557710967487 0.097972574862474 +Endoplasmic reticulum tubular network 7 14 2.1156938882432503 0.0343708507212885 4.456310679611651 11.402912621359222 0.7597390036291544 0.4204688348420043 2.5600618129260964 1.9933849978482647 1.110800197793671 0.3406591463359876 1.0 1.0 1.0 1.0 0.0004867641084232 +Proton transporting atp synthase complex 1 13 2.082582215950469 0.037289321641609 4.157766990291262 11.08495145631068 0.5328143574617974 0.3012358599713604 2.3610641964760792 1.138499586439592 1.3748267965121657 0.2836171984539964 0.0339972376759384 0.0029386578360865 0.0115435449528709 0.062605312422627 0.0078812527225172 +Outer membrane 22 90 1.9883940966983675 0.0467681211762154 28.936893203883496 87.79611650485437 1.4859238244628277 0.3236686433663402 11.632349354832256 8.24751710010496 1.9336855473946637 0.38878066573106 0.0002942416883313 0.0002137267005037 9.636026434398862e-06 3.26585493405961e-05 6.786239126805628e-06 +Proteasome core complex beta subunit complex 5 7 1.962321188259692 0.0497251018913174 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 0.0098489116445482 1.0 0.0841007109914387 0.0188064524051028 2.8311070051942505e-05 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..51d082c5f1275a47e310b4732c55e1b15d14ad65 --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 895, + "title": "Average number of proteins per term", + "value": 28.312849162011172 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2ceabf40daf9328eebe37cdadd8b83adaf86794a --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8eccbaf0b3f5c3a63af857d705c1e96650eb55fd --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,273 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Organelle inner membrane 0.5375199970541206 4.164845214154587 3.115638694661804e-05 0.0275001918101547 0.027884966317224 259 O43615,P00846,Q99720,Q9NX63,O75306,Q99595,O60830,Q567V2,Q70HW3,P03886,Q9Y584,O94901,O14925,O43676,Q9H061,P14406,Q9UDX5,Q69YU5,O75964,P62072,Q13423,Q13505,O43772,Q9UDW1,O75844,Q6P4A7,P22830,Q9BSK2,Q9P0J0,Q8TBP6,Q96NB2,O95831,Q7KZN9,Q9H1E5,Q9Y2R0,Q9BQT8,Q9UBX3,Q53H12,Q5XKP0,P13073,P22695,P20674,O76062,Q6DKK2,O75431,O96000,O95202,P23786,O43819,Q96TA2,Q5T9A4,Q10713,Q15070,O95182,Q9H2V7,P00403,Q9UJS0,Q86VD7,O14949,Q9UJZ1,Q9Y619,O95168,P50402,O75746,Q9Y6C9,Q9H2D1,P06576,P09669,P20700,Q14728,Q9NPL8,P50336,O75880,O75027,Q9NVI7,Q03252,P16260,O95563,Q96BW9,Q86Y39,P60602,Q96IX5,Q96CU9,Q9Y375,O75380,Q5SNT2 86 +Lysosomal lumen 0.698326949055262 3.50684724462769 0.0004534493731562 0.333642676208847 0.1157677363974282 37 O43681,Q14108,P50897,P16278,P38435,P06865,Q9UMR5,P07602,Q13510,O00584,Q9UM22,P06280,P54802,P11117,Q8NHP8 15 +Vacuole 0.4667055942671815 3.456423151018425 0.0005473952681129 0.3874060150518574 0.1157677363974282 201 Q9H7Z7,O43681,Q14108,Q9H2V7,P42785,O75955,Q9UMR5,P07602,O00584,Q9BTY2,Q5BJF2,P04114,Q9Y487,P27105,Q8N511,O60749,Q9UIQ6,P51790,P50897,Q8WTV0,Q93050,P06865,Q8NHS3,Q13510,Q9UM22,Q8NCC3,Q99536,O15118,P07437,Q9NQX7,P16278,Q96EE3,Q13277,Q16625,O75503,O00203,P42892,Q9BXS4,Q8TBX8,Q15165,P38435,Q07065,Q9HC07,P06280,Q9NX40,O75787,P54802,Q9Y679,Q9UHG3,P11117,Q8NHP8,Q9UNK0,O14773,Q9HBH5,P41440 55 +Intrinsic component of organelle membrane 0.477525589573319 3.4237648641259266 0.0006176003409921 0.4247341892888628 0.1157677363974282 153 Q03518,O43752,Q9NX63,Q99595,O60830,Q96NB2,O95470,Q9P0I2,Q8N2H4,P50336,O75880,O43505,Q16799,Q12981,O94901,O43808,Q5BJH7,O14925,Q13586,Q9NPA0,Q92643,Q9NQC3,Q9Y2R0,P10321,Q86XL3,O15118,Q15388,Q8TB61,Q96A33,Q53H12,Q5XKP0,Q9Y5Z9,Q13505,P98194,P51572,O95563,P20020,Q86YN1,O76062,Q15629,P42892,O75431,Q9Y282,P50416,O75844,O95070,O75298,Q6P4A7,Q6ZRP7,O43819,O60499,Q9Y679,Q5SNT2,Q15070 54 +Golgi membrane 0.5305845098503797 3.411212301390688 0.0006467471307118 0.4395559952952418 0.1157677363974282 138 Q9H7Z7,Q9Y3E0,O43752,Q14108,P40616,Q9NRW7,P53367,O00461,P35670,P0CG08,Q8N2H4,Q8IZA0,Q8NCH0,O00400,O43505,Q16799,Q5BJH7,Q15363,P24390,P51790,Q9UP83,Q7LGA3,Q5W0Z9,O95197,O75396,Q15392,P10321,Q8TB61,O43731,P52292,Q86SF2,Q9Y5Z9,Q9H3P7,P50570,Q92896,P98194,Q8NDZ4,P51572,O60476,Q9Y3B3,O14653,Q9Y282,Q9BXS4,O95249,O95070,Q9BVK6,Q9HC07,Q9P2W9,Q6ZRP7,P83436,P35613,Q13190,L0R6Q1,O60499,Q10713,Q6NTF9,P61019,O94923 58 +Intrinsic component of mitochondrial inner membrane 0.6621494554993675 3.2591218933012023 0.0011175763981641 0.6324111461384743 0.1667051460594816 33 Q9NX63,Q15070,Q99595,Q6P4A7,O60830,Q96NB2,Q9Y2R0,O95563,O43819,P50336,O75880,Q53H12,Q5XKP0,O75431,Q13505 15 +Mitochondrial protein containing complex 0.4339426723366227 3.1821194606552035 0.0014620150148334 0.7300344437159362 0.1869290626108485 170 P00846,O95182,Q99595,O60830,P00403,P21796,Q567V2,P03886,Q9Y584,O43676,O14949,P14406,Q9NS69,O75964,Q15388,Q53H12,Q5XKP0,P62072,P13073,Q13505,Q8N4H5,P22695,O95168,P20674,Q9UDW1,O75431,O96000,P06576,Q9P0J0 29 +Nuclear inner membrane 0.7308795865704817 2.9261436950800808 0.0034319237869779 0.9538959545810912 0.2225484707569641 19 O75844,Q99720,Q9H1E5,P50402,P20700,O76062,Q03252,Q5SNT2,Q14728 9 +Mitochondrial envelope 0.4717957653883095 2.871993150086813 0.004078918085038 0.974218479617392 0.2225484707569641 337 O43615,P00846,Q9NX63,Q99595,O75306,O60830,Q9HCL2,P21796,Q567V2,P45880,Q70HW3,P03886,Q9NZJ7,Q9Y584,O43169,O14925,O00264,O43676,Q8NE62,Q9H061,P14406,Q9UDX5,Q9NS69,O75208,Q69YU5,O75964,O43464,P62072,Q13423,Q13505,O43772,Q8N4H5,Q8WY22,P09601,Q9UDW1,Q6P4A7,P22830,Q9BSK2,Q9P0J0,Q8TBP6,Q96A26,Q96NB2,O00584,O95831,Q7KZN9,Q9Y2R0,Q9BQT8,Q99536,Q9UBX3,Q96H78,Q53H12,Q5XKP0,P13073,P22695,P20674,Q6DKK2,O75431,Q13794,O96000,O95202,P23786,O43819,Q96TA2,Q5T9A4,Q10713,Q15070,O95182,Q9H2V7,P00403,Q12981,Q9UJS0,Q86VD7,O14949,Q9UJZ1,Q15388,Q9NQ88,Q9Y619,Q9P0S9,O95168,Q9NVT9,O75746,Q9Y277,P50416,Q9Y6C9,Q9BUK6,Q9H2D1,P06576,P09669,O15294,Q9NPL8,P50336,O75880,O75027,Q92667,Q9NVI7,P16260,Q9Y5Z9,O95563,Q96BW9,Q86Y39,P60602,Q96IX5,Q96CU9,Q9Y375,O75380 105 +Cis golgi network 0.7326042410500373 2.8352123225859245 0.0045795238687598 0.9835608172427758 0.2225484707569641 16 P98194,O43731,Q9NPR9,P24390 4 +Cytochrome complex 0.7314613954081628 2.828755874935311 0.0046729329358921 0.9848851454209308 0.2225484707569641 16 P22695,O14949,P14406,P00403,P20674,Q9UDW1,Q7KZN9,P13073 8 +Proton transporting two sector atpase complex proton transporting domain 0.8241535603529764 2.80899494924065 0.0049696426245753 0.9884251306427224 0.2225484707569641 12 Q93050,P00846,Q9Y487 3 +Snare complex 0.7279290554422041 2.8087677972754603 0.0049731501845131 0.988461591238446 0.2225484707569641 16 O43752,O95249,O15400,Q13277,Q9P2W9,O75396,O60499,Q9UNK0,Q12981,O14653 10 +Inner mitochondrial membrane protein complex 0.5882993112186488 2.791960669254714 0.0052389723723289 0.9909156833550288 0.2232800130111626 85 P00846,Q9NX63,O95182,O75306,Q99595,O60830,P00403,P03886,Q9Y584,O43676,O14949,P14406,O75964,Q53H12,Q5XKP0,P62072,P13073,Q13505,P22695,O95168,P20674,Q9UDW1,O75431,Q86Y39,P60602,O96000,Q96IX5,Q96CU9,P06576,P09669,Q9Y375,Q9P0J0,O75380 33 +Proton transporting two sector atpase complex 0.6580173989719363 2.7449372989806298 0.0060522459944654 0.9956309880214096 0.2369063354826155 25 Q9Y487,P00846,Q93050,Q8N511 4 +Vacuolar lumen 0.586522504087202 2.6395933812202745 0.0083005551993411 0.9994243443981062 0.2800539221376323 64 Q9H7Z7,O43681,Q14108,P50897,P16278,P38435,P06865,Q9UMR5,P07602,Q13510,O00584,Q9BTY2,Q9UM22,Q99536,P06280,P54802,P11117,Q8NHP8 18 +Endoplasmic reticulum golgi intermediate compartment membrane 0.6098595951106213 2.586307800280598 0.0097010256986069 0.999837495773073 0.2800539221376323 28 Q03518,Q15363,P24390,Q9BVK6,O95070,Q96RQ1,O75396,P51572,Q9Y3B3,Q13190,O14653,Q5BJH7,Q9Y282,Q8N511 14 +Nuclear outer membrane endoplasmic reticulum membrane network 0.453822521865172 2.565868743982565 0.0102917764754004 0.9999047368208748 0.2800539221376323 341 Q99720,P30519,Q14108,O14678,Q9NRR5,Q9BZF3,Q03001,Q5BJF2,Q6NUM9,Q16799,Q8N511,O00264,P49458,P07099,P24390,Q92643,P51571,O95197,O75396,O43464,Q86XL3,Q15005,Q9BRR6,Q8WXH0,Q16850,Q8N0U8,O43731,P52292,O14681,P09601,Q9HD20,Q86YN1,Q9Y282,O75844,P43307,Q07065,Q9P2W9,Q8IY17,Q03518,Q5BJH7,Q96G23,Q53GQ0,Q9BT22,P37268,Q15392,O60725,Q8WU17,Q6PIU2,Q9NZ08,Q9Y3B3,Q15800,P51648,O76062,O14653,Q7Z2K6,Q9UBV2,P38435,O75298,Q9Y5M8,Q92575,P46977,Q06136,P16615,Q9BRK0,Q9P0I2,Q96PC5,P67812,Q70UQ0,Q12981,Q13586,Q15363,Q9H3N1,Q9NQC3,Q9UGP8,Q9Y6K0,Q8TB61,Q96A33,Q99943,P50402,P51572,Q14534,Q15629,P16435,O95070,O75787,Q9Y679,Q5VV42,Q9HBH5,Q96KC8,Q96HY6,Q6NUQ1,P48449,O95470,O00400,P04114,O75915,O15269,Q9NPA0,Q96RQ1,P10321,O60762,Q9Y5Z9,Q5JRA6,Q8NHH9,Q96N66,O43852,A1L0T0,Q96AG4,Q9BVK6,Q9BV10,Q8TDW0,P04843 112 +Membrane protein complex 0.4420324131746365 2.5647166050948385 0.0103260105369182 0.9999076408544052 0.2800539221376323 293 P00846,Q9NX63,P02786,O75306,O14678,Q4KMQ2,Q99595,O60830,Q5VZ89,P21796,P45880,P03886,Q9Y584,Q9Y487,O94901,Q9C0H2,O14925,Q8N511,O43676,P49458,Q92643,Q93050,P14406,P51571,O75396,Q9NS69,O43464,O75964,Q14344,Q15005,P62072,Q13505,Q8N4H5,Q8NDZ4,Q9UDW1,Q9P2W9,Q9P0J0,P41440,Q03518,Q53GQ0,Q53H12,Q5XKP0,Q8WU17,P13073,P22695,Q13277,Q9Y3B3,P20674,O14653,O75431,O96000,Q9UBV2,Q9Y5M8,Q8NC96,O60499,P46977,Q9UNK0,O43752,O95182,Q9P0I2,P00403,P67812,Q12981,P04899,O14949,Q9UGP8,Q15388,O95168,O00203,Q9Y277,O95249,P06576,P09669,O75787,Q9Y679,O75955,O15269,O60749,Q9NPA0,O15400,P10321,Q9Y5K8,Q86Y39,P60602,Q96IX5,Q96CU9,P63218,Q9Y375,Q8TDW0,O75380,P04843 91 +Organelle subcompartment 0.4620262862602391 2.544287842835352 0.0109500808360774 0.999947483043246 0.2806940865028225 402 Q99720,P30519,Q14108,O14678,Q9NRR5,P35670,Q9BZF3,Q03001,Q5BJF2,Q6NUM9,Q16799,Q8N511,O00264,P49458,Q9NPR9,P07099,P24390,Q96A57,Q92643,P51571,O95197,O75396,O43464,Q86XL3,Q15005,Q9BRR6,Q8WXH0,Q16850,Q8N0U8,O43731,P52292,O14681,P98194,P09601,Q9HD20,Q86YN1,Q9Y282,O75844,P43307,Q07065,Q9P2W9,Q8IY17,Q03518,O00461,P0CG08,Q5BJH7,Q96G23,Q53GQ0,Q9BT22,P37268,Q15392,O60725,Q8WU17,Q6PIU2,Q9NZ08,Q9Y3B3,Q15800,P51648,O76062,O14653,Q7Z2K6,Q9UBV2,P38435,O75298,Q9HC07,Q9Y5M8,Q92575,O60499,P46977,Q10713,Q9UNK0,Q06136,O43752,P16615,Q00765,Q9BRK0,Q9P0I2,Q8N2H4,Q96PC5,O15127,P67812,Q70UQ0,Q12981,Q13586,Q15363,Q9H3N1,Q9NQC3,Q9UGP8,Q9Y5X1,Q9Y6K0,Q8TB61,Q96A33,Q99943,P50402,P51572,Q14534,Q15629,Q9P260,Q9BXS4,P16435,O95249,O95070,O75787,Q9Y679,Q5VV42,Q9HBH5,Q96KC8,Q96HY6,Q6NUQ1,P48449,O95470,O00400,P04114,O75915,O15269,Q9NPA0,Q9UP83,Q96RQ1,P10321,Q9BSR8,O60762,Q9Y5Z9,Q5JRA6,P50570,Q4J6C6,Q8NHH9,Q96N66,O43852,A1L0T0,Q96AG4,Q9BVK6,Q9BV10,P83436,Q8TDW0,P40616,P04843 136 +Outer mitochondrial membrane protein complex 0.6805990137359642 2.536143720556205 0.011208072522419 0.9999584188601446 0.2806940865028225 16 Q8N4H5,Q9NS69,Q5XKP0,O75431,Q13505 5 +Intrinsic component of golgi membrane 0.6779383228900209 2.5205476152269046 0.0117172384213362 0.9999737764184898 0.2806940865028225 16 O95070,P98194,Q5W0Z9,Q6ZRP7,Q8N2H4,L0R6Q1,Q8TB61,O43505,Q9Y282,Q5BJH7,Q9Y5Z9 11 +Golgi apparatus 0.440777766894966 2.512549704751326 0.0119862218779578 0.9999794464955384 0.2806940865028225 300 Q9H7Z7,Q14108,Q5VW38,Q9NRW7,Q5VZ89,P35670,Q16799,Q9NPR9,P24390,P50897,Q96A57,Q93050,Q7LGA3,Q5W0Z9,O95197,O15118,O43731,P16278,Q92896,P98194,Q8NDZ4,P80303,O75503,O60476,Q9UQB8,Q9Y282,Q9P2W9,P06280,Q9UI14,O00461,P0CG08,Q8IZA0,Q8NCH0,Q5BJH7,P51790,Q15392,Q9H3P7,Q9NQX7,Q9BRK5,Q9Y3B3,Q6P1K2,O14653,O14976,Q9HC07,Q9NX40,O60499,Q10713,Q9UNK0,O14773,Q9Y3E0,O43752,O95456,Q8N2H4,O15127,Q15363,Q02818,Q9Y5X1,Q9Y6K0,Q8TB61,Q9GZM5,P51572,Q96PU5,O00203,Q9P260,Q9BXS4,O95249,O95070,Q8NEY8,O94923,O00400,O43505,Q9UP83,Q96RQ1,P10321,Q9BSR8,Q86SF2,Q9Y5Z9,P50570,Q4J6C6,O43852,Q9BVK6,Q6ZRP7,P83436,Q8IY95,P40616 85 +Respiratory chain complex iv 0.8308843303121017 2.475874661330652 0.0132910228551494 0.9999937016597652 0.2806940865028225 9 P22695,P14406,P00403,P20674,P13073 5 +Intrinsic component of mitochondrial membrane 0.5678369503964169 2.4736317793842777 0.0133747467879181 0.9999941622780044 0.2806940865028225 51 Q9NX63,Q15070,Q99595,Q6P4A7,O60830,Q96NB2,Q9Y2R0,O95563,O43819,P50336,Q15388,P50416,O75880,Q53H12,Q5XKP0,O75431,Q13505 17 +Respirasome 0.5640835472647815 2.4509350347251067 0.0142485667049077 0.9999973585742468 0.2806940865028225 47 O95182,P00403,P03886,Q7KZN9,O43676,O14949,P14406,Q13423,P13073,P22695,O95168,P20674,Q9UDW1,Q6DKK2,Q86Y39,O96000,Q96CU9,P09669,Q9Y375,Q9P0J0,O75380 21 +Tim23 mitochondrial import inner membrane translocase complex 0.8163299806936269 2.4107389101372902 0.0159202406256817 0.9999994217470308 0.2806940865028225 9 Q99595,O60830 2 +Copi coated vesicle 0.7002977092838759 2.4019377536632547 0.0163084832381528 0.9999995938009898 0.2806940865028225 14 P24390,Q8NDZ4,Q9Y3B3,O43731,Q8N511 5 +Copi coated vesicle membrane 0.7088534123110722 2.3410393539361776 0.019230139987969 0.9999999716492578 0.3008134585756645 13 P24390,Q8NDZ4,Q9Y3B3,O43731,Q8N511 5 +Proton transporting atp synthase complex coupling factor f o 0.8210952109023648 2.328141245498275 0.0199046048020048 0.999999984683056 0.3008134585756645 8 P00846 1 +Lipid droplet 0.5401104397121869 2.323239956632975 0.0201662653793741 0.9999999879388988 0.3008134585756645 33 Q99720,Q9H6V9,P48449,Q07065,P51572,Q9Y679,Q8NBX0,O43760 8 +Golgi associated vesicle membrane 0.6275948142299124 2.269922921238123 0.0232122601234752 0.9999999992566746 0.3246089501642237 18 P24390,Q8NDZ4,Q9Y3B3,O43731,Q8N511 5 +Rough endoplasmic reticulum membrane 0.6608721854420047 2.18222147276759 0.0290931912816023 0.9999999999966588 0.3566904958497825 14 P49458,Q9UGP8,Q9Y5M8,Q5BJF2 4 +Endocytic vesicle membrane 0.5240064524677928 2.1316311912527444 0.0330371774887408 0.9999999999999124 0.3701905980465583 43 Q14108,Q8WTV0,Q93050,Q5KU26,Q9Y487 5 +Endoplasmic reticulum tubular network 0.6491320429553442 2.1156938882432503 0.0343708507212885 0.9999999999999746 0.3706254385006414 14 Q6NUK4,Q00765,Q9BRK0,Q9NQC3,Q8NHH9,P50402,Q13586 7 +Proton transporting atp synthase complex 0.6612116331181725 2.082582215950469 0.037289321641609 0.9999999999999984 0.3797479258454678 13 P00846 1 +Outer membrane 0.4994431351187329 1.9883940966983673 0.0467681211762154 1.0 0.4500803059431484 90 Q99720,Q9HCL2,P21796,P45880,O43169,Q9NS69,Q99536,Q15388,Q53H12,Q9NQ88,Q5XKP0,Q13505,Q8N4H5,Q8WY22,P09601,P50402,Q9NVT9,Q9Y277,O75431,Q13794,P50416,Q9Y6C9 22 +Proteasome core complex beta subunit complex 0.7737374506279218 1.962321188259692 0.0497251018913174 1.0 0.4684628020287271 7 P28074,P28072,P49721,P28070,P20618 5 +Proton transporting v type atpase complex 0.6566862013765127 1.9554236560475704 0.0505330862212014 1.0 0.4711157517497427 12 Q9Y487,Q8N511 2 +Endoplasmic reticulum 0.4308974562983066 1.9213794904561732 0.0546838822699251 1.0 0.4894207463158301 511 Q99720,P30519,Q14108,Q9H2J4,Q9H6V9,Q92791,O14678,Q9NRR5,Q9BZF3,Q03001,Q5BJF2,Q6NUM9,Q16799,O43390,Q8N511,O00264,P49458,P07099,P24390,Q96A57,Q92643,Q5W0Z9,P51571,O95197,O75396,O43464,Q86XL3,Q15005,Q9BRR6,O15118,Q8NBJ7,Q8WXH0,Q16850,Q8N0U8,O43731,P52292,O14681,P98194,P80303,P09601,Q9HD20,O75503,O60476,Q86YN1,Q9UMX5,Q9UQB8,Q9Y282,O75844,P43307,Q9UNW1,Q07065,Q14257,Q9P2W9,Q8IY17,Q03518,O15173,O43681,O00584,Q9BTY2,P27105,Q13641,Q5BJH7,Q96G23,Q53GQ0,Q9BT22,P37268,Q15392,Q13510,O60725,Q14145,Q8WU17,Q6PIU2,Q9NZ08,Q9BRK5,Q9Y3B3,Q15800,P51648,O76062,O14653,Q7Z2K6,Q9UBV2,P38435,O75298,Q9Y5M8,Q92575,Q8IXB1,P46977,Q9UNK0,Q06136,Q9Y3E0,O95456,P16615,Q00765,Q9BRK0,Q9P0I2,Q96PC5,P67812,Q70UQ0,Q12981,Q13586,Q9NWM8,Q15363,Q02818,Q9H3N1,Q9NQC3,Q9UGP8,Q9Y6K0,Q8TB61,Q96A33,Q99943,Q9H6E4,P50402,P51572,Q92530,O95302,Q14534,Q15629,Q8TBX8,P16435,O95070,O75787,Q9Y679,Q5VV42,O75718,Q9HBH5,Q96KC8,Q96HY6,Q6NUQ1,P48449,O95470,O00400,P04114,O75915,O15269,Q9NPA0,Q96RQ1,P10321,Q9BSR8,O60762,Q32P28,Q9Y5Z9,Q5JRA6,P61916,Q8NHH9,Q96N66,O43852,A1L0T0,Q96AG4,Q9NUQ7,Q9C0I1,Q9BVK6,Q9BV10,P10619,O60506,Q8IY95,Q8TDW0,P04843 157 +Haus complex 0.88635749252215 1.8976236094464407 0.0577456820437798 1.0 0.5034053747581642 4 Q9H6D7 1 +Golgi associated vesicle 0.5237263034338396 1.8961984891139352 0.0579338029051295 1.0 0.5034053747581642 27 P24390,Q8NDZ4,Q9Y3B3,O43731,Q8N511 5 +Tim22 mitochondrial import inner membrane insertion complex 0.8824359085848826 1.8824207542642235 0.0597789101801178 1.0 0.5038784360697239 4 P62072,Q9Y584 2 +Pore complex 0.6814148561421343 1.8790313312992872 0.0602402152619669 1.0 0.5038784360697239 10 P21796 1 +Organelle membrane contact site 0.5671879079662743 1.8640753260638971 0.0623111269691061 1.0 0.5116372352050457 17 Q9Y320,Q13637,O96008,Q96N66,P51572,Q15388,Q5XKP0 7 +Synaptic vesicle membrane 0.5853915470930708 1.8467592207060195 0.0647820444911075 1.0 0.5185078828932663 15 O43752,Q15907,O15126,O60499,P20020,O76024,O43760,Q86Y82 8 +Mitotic spindle microtubule 0.7658603946877093 1.84328353877144 0.0652876232804646 1.0 0.5185078828932663 6 Q9H6D7 1 +Azurophil granule membrane 0.544021449931742 1.8420677455298584 0.0654652410803788 1.0 0.5185078828932663 22 P27105,P42785,Q07065,P07602 4 +Endoplasmic reticulum golgi intermediate compartment 0.4933264889567441 1.8369932687229311 0.0662108891021042 1.0 0.519813559178801 50 Q03518,Q15363,P24390,Q02818,P80303,P51572,Q9Y3B3,O14653,Q5BJH7,Q9Y282,Q8N511 11 +Rough endoplasmic reticulum 0.4769824247654933 1.80769005856003 0.0706547527224348 1.0 0.5293993803619691 32 P49458,Q07065,Q9UGP8,Q9Y5M8,Q5BJF2,Q96A33,Q9UQB8 7 +Exocytic vesicle 0.483278703618134 1.8074163537749808 0.0706973859720649 1.0 0.5293993803619691 39 O43752,P51790,O15400,P50897,Q9BVK6,Q13277,Q9BT78,Q9NRW7,O60499,P20020,Q9UI14,O43760 12 +Envelope 0.4250762786064058 1.8032597888224131 0.071347424592699 1.0 0.5293993803619691 495 O43615,P00846,Q99720,Q9NX63,Q99595,O75306,O60830,Q9HCL2,P21796,Q567V2,P45880,Q70HW3,Q9BZF3,P03886,Q5BJF2,Q9Y584,P57740,Q03001,O43169,Q9NZJ7,Q6NUM9,O94901,O14925,O00264,O43676,Q9H061,P14406,Q9UDX5,Q9NS69,Q69YU5,O75964,O15118,P62072,Q13423,Q13505,O43772,Q8N4H5,Q8WY22,P80303,P09601,Q9UDW1,O75844,Q6P4A7,P22830,Q9BSK2,Q9P0J0,Q8TBP6,O15173,Q96A26,Q96NB2,O00584,O95831,Q7KZN9,Q9BTX1,Q9H1E5,Q9Y2R0,Q9BQT8,Q99536,Q9UBX3,Q96H78,Q53H12,Q5XKP0,P13073,P22695,P41208,P20674,O76062,Q6DKK2,O75431,Q13794,O96000,O95202,Q92575,P23786,O43819,Q96TA2,Q5T9A4,Q10713,Q15070,O95182,Q9H2V7,Q96RT1,P00403,Q12981,Q9UJS0,Q86VD7,O14949,Q9NQC3,Q9UJZ1,Q9Y6K0,Q15388,Q9NQ88,P07437,Q9Y619,Q96EE3,Q9P0S9,O95168,P50402,Q9NVT9,O75746,Q9Y277,P50416,Q9Y6C9,P42167,Q9BUK6,Q9UI26,Q9H2D1,P06576,P09669,P20700,Q14728,Q96KC8,O15294,Q9NPL8,P50336,O75880,O75027,Q92667,Q9NVI7,Q03252,P16260,Q9Y5Z9,Q8WWI1,Q8N1F7,O95563,Q96BW9,Q96AG4,Q86Y39,P60602,Q96IX5,Q96CU9,Q6ZRP7,P67809,Q9Y375,O75380,Q7Z3B4,Q5SNT2 137 +Azurophil granule 0.4887873271071424 1.7704207360470745 0.0766570779273303 1.0 0.5328889236643941 66 Q9H7Z7,O43681,Q9NQX7,P16278,P06865,P42785,Q07065,P07602,P06280,O00584,Q9BTY2,Q99536,P27105 13 +Specific granule membrane 0.5508127438170104 1.7585457480387052 0.0786546946856439 1.0 0.5328889236643941 17 P30519,Q07065,Q4KMQ2,Q08722,P27105,Q9Y5K8,O00264 7 +Cis golgi network membrane 0.9770671834625309 1.7373319890279315 0.0823285882695479 1.0 0.5347983779387009 2 Q9NPR9 1 +Phagocytic vesicle membrane 0.5067313912270445 1.7220684181971886 0.0850571253112808 1.0 0.5347983779387009 26 Q03518,Q04656,P50570,Q13637,Q93050,O75396,Q6WKZ4,P10321,P04439,Q9Y487,Q15907 11 +Integral component of synaptic vesicle membrane 0.73285899094437 1.700628397841547 0.0890127881633213 1.0 0.5492986888762112 6 O43752,O15126,O60499,P20020,O76024 5 +Perinuclear region of cytoplasm 0.3404703409383577 1.6946569099344349 0.0901405243858357 1.0 0.5492986888762112 167 Q9H7Z7,O43752,Q9H2J4,Q96F07,P02786,Q9UL15,Q9NRR5,P35670,O95831,Q9BZF3,Q9Y487,P27105,Q9Y4G8,Q9UIQ6,O15400,Q93050,O15118,Q9NQX7,P16278,P16989,P50570,P09601,O75503,P51572,Q92530,Q96S55,P42892,Q9UBB4,O14976,Q07065,O75935,O60499,Q8IY95,Q99627,Q9UNK0 35 +Proton transporting v type atpase v0 domain 0.8333724123852277 1.6906090927134505 0.0909114868895293 1.0 0.5492986888762112 4 Q9Y487,Q93050 2 +Vacuolar proton transporting v type atpase v0 domain 0.8333724123852277 1.6906090927134505 0.0909114868895293 1.0 0.5492986888762112 4 Q9Y487,Q93050 2 +Dynactin complex 0.8300678878186872 1.6775905326429827 0.0934270622814494 1.0 0.5574481382793153 4 O75935,Q9UJW0 2 +Caveola 0.5862307718640715 1.6602689297151951 0.0968603632815203 1.0 0.5741061267348393 13 P09601,Q8WTV0 2 +External side of plasma membrane 0.5115659534735981 1.6451026584835475 0.0999486424667277 1.0 0.5858988755501471 23 P51790,O96005,O75955,Q4VCS5,O75787,P08183,P00390,P42892,P41440 9 +Schaffer collateral ca1 synapse 0.5524045078738782 1.6440820793912627 0.1001592491163938 1.0 0.5858988755501471 15 Q13277,P07196,Q9UQB8,Q9BVA1 4 +Mib complex 0.6329053173078166 1.6349628706609691 0.1020568313393164 1.0 0.5892958970883109 10 Q5XKP0,Q13505 2 +Phagocytic vesicle 0.4654070920965268 1.62525734393076 0.1041077363413898 1.0 0.597284769394512 43 Q03518,O43752,Q04656,P51790,Q9UNK0,P50570,Q13637,Q93050,O75396,P10321,P04439,P08670,Q6WKZ4,Q9Y487,Q15907 15 +Gtpase complex 0.7473941766231242 1.6043938822141683 0.1086272586743741 1.0 0.6023921342253076 5 P63218,Q14344,P04899 3 +Nadh dehydrogenase complex 0.4849421021067701 1.5986727644132384 0.1098933323210662 1.0 0.6023921342253076 27 O43676,O96000,O95182,O95168,Q96CU9,P03886,Q9Y375,Q9P0J0,O75380,Q86Y39 10 +Clathrin coated vesicle 0.4586313457307072 1.5717667042666514 0.1160046659725919 1.0 0.6023921342253076 42 O43752,Q14108,Q9BVK6,P50570,Q5VW38,Q9Y5X1,P51572,Q8NC96,O00203,P04114,P42892 11 +Golgi cisterna 0.5148346375207391 1.5605155086564155 0.1186381079493241 1.0 0.6023921342253076 19 Q15363,P98194,O00461,P51572,P0CG08,Q10713,Q9BXS4 7 +Vacuolar membrane 0.4264400455190341 1.553915175721453 0.1202046513167589 1.0 0.6023921342253076 117 Q14108,Q9H2V7,P42785,P07602,Q9Y487,P27105,Q8N511,Q9UIQ6,P51790,Q8WTV0,Q93050,Q8NHS3,O15118,Q9NQX7,Q96EE3,Q16625,O75503,O00203,P42892,Q9BXS4,Q07065,Q9HC07,O75787,P11117,Q9UNK0,Q9HBH5,P41440 27 +Coated vesicle 0.4588465081333696 1.5438475844382489 0.1226252605838036 1.0 0.6023921342253076 86 O43752,Q14108,Q5VW38,P04114,Q5BJH7,Q8N511,Q15363,P24390,Q96RQ1,Q9Y5X1,P10321,O43731,P50570,Q8NDZ4,P51572,Q9Y3B3,O00203,O14653,P42892,Q9Y282,O95070,Q8NC96 22 +Mitochondria associated endoplasmic reticulum membrane 0.5977803651288786 1.537693818839463 0.1241234956978014 1.0 0.6023921342253076 11 Q9Y320,Q13637,O96008,Q96N66,P51572,Q15388 6 +Plasma membrane raft 0.5112577410062752 1.5361950894815075 0.1244905400093441 1.0 0.6023921342253076 19 Q13586,P09601,P41440,Q8WTV0 4 +Golgi medial cisterna 0.7819532810036308 1.4868593567432171 0.1370519606324081 1.0 0.6355518381658303 4 O95249,Q9BXS4 2 +Cyclin dependent protein kinase holoenzyme complex 0.6201103823476279 1.4814056425520556 0.1384985120327004 1.0 0.6389493209756028 9 P12004,P14635,P11802,Q9P287,P50750 5 +Postsynaptic specialization intracellular component 0.7155886217237419 1.469887069633977 0.1415923421446894 1.0 0.6400487499624387 5 Q9UQB8 1 +Intrinsic component of synaptic vesicle membrane 0.6006441197064742 1.4695515694289607 0.1416832452153431 1.0 0.6400487499624387 10 O43752,O15126,O60499,P20020,O76024,Q86Y82 6 +Postsynaptic specialization membrane 0.6314632088066079 1.4573648932629502 0.1450156824956305 1.0 0.6425199793742047 8 Q15375,Q99720,P52292 3 +Azurophil granule lumen 0.4415441046042224 1.4419443035418298 0.1493180865328192 1.0 0.6550412039752082 39 Q9H7Z7,O43681,P16278,P06280,O00584,Q9BTY2 6 +Trans golgi network membrane 0.451625803199271 1.4247990289275188 0.1542153031174464 1.0 0.6550412039752082 29 Q04656,O43752,Q9UP83,O15126,Q9Y2V7,Q9HC07,P53367,P83436,Q8N2H4,P35670,O60499,O15127,P40616 13 +Striated muscle thin filament 0.6988379561299071 1.3986439375683088 0.1619197836377273 1.0 0.6550412039752082 5 P28289,P67936 2 +Myofilament 0.6988379561299071 1.3986439375683088 0.1619197836377273 1.0 0.6550412039752082 5 P28289,P67936 2 +Zymogen granule 0.6972973693357303 1.392080208604246 0.1638981107028785 1.0 0.6550412039752082 5 Q13277 1 +Lsm1 7 pat1 complex 0.7569028007219003 1.3868741939629243 0.1654801281073186 1.0 0.6550412039752082 4 P62310,Q9Y4Y9 2 +Neuron projection terminus 0.5110818235244049 1.3849989361277593 0.1660527926713151 1.0 0.6550412039752082 15 Q13641,Q9UQB8 2 +Cell trailing edge 0.6608514232063651 1.3834186592463935 0.1665365324413534 1.0 0.6550412039752082 6 P41440 1 +Organelle envelope lumen 0.4313381627848698 1.376256834813338 0.1687421316738968 1.0 0.6550412039752082 36 P07437,Q9UJZ1,P36404,O43464,O00584,Q6FI81,O95831,P50336,O60313,Q53H12,P62072,O14925 12 +Ciliary transition zone 0.657462416017135 1.3683278817951705 0.171209467119739 1.0 0.6550412039752082 6 A6NIH7 1 +Endocytic vesicle 0.4422231285991118 1.3617237743433035 0.1732850753986441 1.0 0.6550412039752082 84 Q03518,Q14108,P51790,Q8WTV0,Q93050,O00461,Q4VCS5,Q16625,P08670,Q5KU26,Q9Y487,Q9UNK0 12 +Excitatory synapse 0.7502948433776011 1.360449262795126 0.1736877982993978 1.0 0.6550412039752082 4 Q9UQB8 1 +Specific granule 0.4263012469391705 1.3592164104815143 0.174078022617045 1.0 0.6550412039752082 33 P27105,P30519,P51790,Q07065 4 +Postsynaptic density intracellular component 0.7487560197253065 1.3542933890668325 0.1756427944474135 1.0 0.6550412039752082 4 Q9UQB8 1 +Dna replication preinitiation complex 0.5937050206147529 1.3498299392307955 0.1770705389608808 1.0 0.6550412039752082 9 Q9BRX5,P33991 2 +Dopaminergic synapse 0.8727390180878453 1.321985167379375 0.1861730901262226 1.0 0.6550412039752082 2 P41440 1 +Intrinsic component of nuclear inner membrane 0.6465071151358307 1.319473348011129 0.1870109145617744 1.0 0.6550412039752082 6 Q9BTV4,Q9Y2U8,Q8NC56,O94901,Q5SNT2 5 +Golgi cisterna membrane 0.526933126747977 1.314309677353271 0.1887420119387153 1.0 0.6550412039752082 13 Q15363,P98194,O00461,P0CG08,Q10713 5 +Intrinsic component of plasma membrane 0.4382426657295184 1.3017775979001012 0.1929924240005682 1.0 0.6550412039752082 79 P16615,P02786,Q9BRK0,O96005,P35670,O60637,O00400,P27105,P33527,Q13641,Q13586,O00264,Q9UJS0,Q9Y4G8,Q9UIQ6,P51790,Q8WTV0,Q15758,O43464,Q08722,P10321,O15118,P53985,Q15375,P51572,P20020,O76062,P30825,Q8TDW0,Q9UNK0,O43657,P41440 32 +Lsm2 8 complex 0.631569551302911 1.2527125018795944 0.2103103545127078 1.0 0.6795899715065211 6 P62310,Q9Y4Y9 2 +Golgi stack 0.44350741016829 1.235878026367347 0.2165039059912914 1.0 0.682292238951429 26 Q15363,P98194,O00461,P51572,P0CG08,Q10713,Q9BXS4 7 +Respiratory chain complex iii 0.6059483137112591 1.20671083458787 0.2275435250589592 1.0 0.6879401973778897 7 Q9UDW1,P22695 2 +Cortical endoplasmic reticulum 0.8603793163769664 1.2015755244631323 0.2295280290001664 1.0 0.6879401973778897 3 Q13586 1 +Zymogen granule membrane 0.7099686045054302 1.1990284797736956 0.2305168717690411 1.0 0.6879401973778897 4 Q13277 1 +Centriolar satellite 0.4538953898384726 1.198828907931517 0.2305944795680077 1.0 0.6879401973778897 22 Q03518,P41440,Q14145 3 +Myosin ii complex 0.7087912087912098 1.1943174645269967 0.232353808532526 1.0 0.690788675451327 4 P14649,P60660,P35580 3 +Histone pre mrna 3 end processing complex 0.8388242894056843 1.1877253541101342 0.2349416314479653 1.0 0.6938958330638563 2 P67809 1 +Copii coated er to golgi transport vesicle 0.4020154206863826 1.1337228547341525 0.2569108196937246 1.0 0.727027260411796 34 Q15363,Q9BVK6,O95070,Q96RQ1,O75396,P10321,Q9Y3B3,P04439,Q13190,Q969X5,O14653,Q5BJH7,Q9Y282 13 +Coated vesicle membrane 0.4171636413337889 1.1154179489908138 0.2646713614451768 1.0 0.7325098895137421 56 Q15363,Q14108,P24390,Q8NDZ4,Q8NC96,Q9Y3B3,O00203,P04114,O43731,O14653,Q8N511 11 +Microtubule organizing center attachment site 0.81750645994832 1.1040418274000137 0.2695749938845972 1.0 0.7325098895137421 2 O94901 1 +Cop9 signalosome 0.5577181804526035 1.100938644970238 0.2709233613132484 1.0 0.7325098895137421 8 Q9BT78 1 +Intrinsic component of postsynaptic density membrane 0.8149224806201575 1.093948530449384 0.2739775524452501 1.0 0.7343404358264037 2 Q15375 1 +Membrane microdomain 0.4162689755013767 1.0916199127970996 0.2750001999147111 1.0 0.7343404358264037 60 P04899,P50897,Q8WTV0,Q9UJZ1,P09601,P21796,O15118,P27105,Q13586,O14773,P41440 11 +Nuclear outer membrane 0.541101337747727 1.0851749244020288 0.2778441880276565 1.0 0.7343404358264037 9 Q6NUM9,Q99720,P50402 3 +Proteasome core complex 0.4633832977355954 1.0807645131574672 0.2798018776608302 1.0 0.7343404358264037 15 P28074,P28072,P49721,Q92530,P28070,P20618 6 +Vesicle membrane 0.3366140179119196 1.0680338688451252 0.2855052344032729 1.0 0.7406585066403747 240 Q03518,O43752,P30519,Q14108,P42785,O00461,P07602,Q9BZF3,O15127,Q9Y487,P27105,O43760,Q8N511,Q15363,Q9UIQ6,P24390,P51790,Q8WTV0,Q93050,O15118,O43731,Q9NQX7,Q13277,Q8NDZ4,Q9Y3B3,Q5KU26,O14653,P42892,Q9UBB6,Q07065,Q9HC07,Q8NC96,O60499,Q5T9A4,Q9UNK0 35 +Micos complex 0.6207585282638428 1.0650382064163906 0.2868586406011681 1.0 0.7420187379712299 5 Q5XKP0 1 +Platelet alpha granule lumen 0.5219874351507234 1.0590307321321997 0.2895857838730111 1.0 0.7447512906232615 10 Q8NBX0,Q8NBM8 2 +U6 snrnp 0.572339058972522 1.0514975165170024 0.2930301494196308 1.0 0.7493199535159131 7 P62310,Q9Y4Y9 2 +Dendrite membrane 0.8151857835218108 1.0385279919076371 0.2990243103002483 1.0 0.7502144555034063 3 P20020,O75787 2 +Dendritic spine membrane 0.8151857835218108 1.0385279919076371 0.2990243103002483 1.0 0.7502144555034063 3 P20020,O75787 2 +Platelet dense tubular network membrane 0.7965116279069631 1.0224155448929748 0.3065842662514761 1.0 0.7562190282193304 2 P16615 1 +Platelet dense tubular network 0.7965116279069631 1.0224155448929748 0.3065842662514761 1.0 0.7562190282193304 2 P16615 1 +Atp binding cassette abc transporter complex 0.7923126614987095 1.0062054818148318 0.3143167357514982 1.0 0.7562190282193304 2 O14678 1 +Neuromuscular junction 0.4725462831343561 0.9913550636996904 0.3215122343009142 1.0 0.7587170726513409 13 Q15375,P35579,P07196,Q12955,P46109,P57105,O43760 7 +Perinuclear endoplasmic reticulum 0.6033365641890276 0.9908720859839688 0.3217480442319176 1.0 0.7587170726513409 5 Q9BZF3 1 +Mhc protein complex 0.7877906976744227 0.988796917952347 0.3227625125011848 1.0 0.7587170726513409 2 P10321 1 +Mhc class i protein complex 0.7877906976744227 0.988796917952347 0.3227625125011848 1.0 0.7587170726513409 2 P10321 1 +Nuclear cyclin dependent protein kinase holoenzyme complex 0.7845607235142167 0.9763944524637476 0.3288690295433922 1.0 0.7645137180294443 2 Q9P287 1 +Mitochondrial crista 0.6477345594216275 0.9514394845564436 0.3413813245827799 1.0 0.7847706506201183 4 O60313 1 +Extrinsic component of cytoplasmic side of plasma membrane 0.4296201255512504 0.9502857075198946 0.3419670991529007 1.0 0.7847706506201183 17 P04899,Q9Y5X1,P63218,Q14344,Q9Y4F1 5 +Sarcoplasmic reticulum membrane 0.5110400269552194 0.933611493539256 0.3505043343793654 1.0 0.7913986208657466 9 Q13586,P16615,O75298 3 +Triglyceride rich plasma lipoprotein particle 0.7850389539308451 0.931342365541058 0.3516764937025827 1.0 0.7913986208657466 3 Q9UHG3 1 +Early endosome lumen 0.7709948320413231 0.9246222498240096 0.3551624352480425 1.0 0.7913986208657466 2 Q9UIQ6 1 +Beta catenin destruction complex 0.6395250038392437 0.9191595673255336 0.3580121161000047 1.0 0.7913986208657466 4 P35222,Q9HB71 2 +Endoplasmic reticulum tubular network membrane 0.7812600969305363 0.918031586481314 0.3586023295032756 1.0 0.7913986208657466 3 Q9NQC3,Q8NHH9 2 +Golgi lumen 0.6378170871897593 0.912460952284822 0.3615261158706699 1.0 0.7913986208657466 4 O00461 1 +Stereocilium bundle 0.5839171393821054 0.9086860364091236 0.3635158770068774 1.0 0.7913986208657466 5 Q00013,Q9Y6M7 2 +Cul3 ring ubiquitin ligase complex 0.5542380621449372 0.9069877715667376 0.3644132638496609 1.0 0.7913986208657466 6 Q14145 1 +Recycling endosome 0.3774245095613062 0.8933234506575845 0.3716839831806342 1.0 0.8015835299919701 36 P51790,O15400,Q9H267,P02786,Q96A57,O15126,P10321,P04439,O14773,O15127,Q9H4M9,Q6WKZ4,Q9UNK0,Q15907,Q9P260 15 +Flotillin complex 0.5478920600240437 0.8788556618917509 0.3794795415881062 1.0 0.8105827916977448 6 Q14254,O75955,P35221,P41440 4 +Extrinsic component of postsynaptic membrane 0.6284866071851449 0.8759795373092748 0.3810411580883728 1.0 0.8119805630692706 4 P52292,Q9Y4F1 2 +Hrd1p ubiquitin ligase erad l complex 0.5682560602075002 0.8429471459560157 0.3992580043427569 1.0 0.8219336621591183 5 Q9Y679,Q9UBV2,Q6NTF9 3 +Endosome 0.2989918938527631 0.8400560534233495 0.4008769588001819 1.0 0.8219336621591183 181 O43752,Q14108,P02786,Q5VW38,Q9NRW7,O00461,P07602,P35670,P31751,O75955,P04439,Q9BZF3,O15127,Q9NZJ7,Q969Q5,Q9Y487,Q6WKZ4,P04114,O60749,Q9Y4G8,Q9UIQ6,P51790,O15400,Q96A57,Q9H267,Q93050,Q9GZP9,Q13510,P10321,O15118,Q96J02,Q15907,Q04656,Q13637,P50570,Q9BRK5,Q96PU5,A4D1P6,P18031,O14653,P42892,Q9P260,Q9BXS4,Q9UBB6,Q6IAA8,Q9HC07,O60831,Q9NX40,O75787,P35613,Q8IY95,Q9H4M9,Q9UNK0,O14773,P41440 55 +Atpase dependent transmembrane transport complex 0.5666948776641092 0.8364269233986823 0.4029147715366727 1.0 0.8219336621591183 5 O14678,Q9NUT2 2 +Transporter complex 0.3880027750431383 0.8346608988744998 0.4039086630531314 1.0 0.8219336621591183 57 O95182,O75306,O14678,P03886,Q9C0H2,O43676,O14949,P62072,P22695,O95168,O75381,Q9UDW1,Q86Y39,O96000,Q96CU9,Q9Y375,Q9P0J0,Q8TDW0,O75380 19 +Clathrin coated vesicle membrane 0.4031145939612366 0.8276456355233383 0.4078712155619737 1.0 0.8219509376859245 22 O00203,Q14108,P04114,Q8NC96 4 +Intrinsic component of endoplasmic reticulum membrane 0.3889800751507267 0.8156490626865246 0.4147008799059337 1.0 0.8262457290639665 64 Q03518,O75844,Q9NPA0,O75298,O95470,Q9NQC3,Q9P0I2,Q15629,P51572,Q86XL3,Q9Y679,Q8TB61,Q86YN1,Q96A33,O76062,Q12981,Q13586,Q9Y282 18 +Mcrd mediated mrna stability complex 0.6117473273924459 0.8110827561262461 0.4173181478065619 1.0 0.8262457290639665 4 P11940,O60506 2 +Endosome lumen 0.5576751604986638 0.7988916373282139 0.4243532484276153 1.0 0.8299886378585855 5 Q9UIQ6,P04114 2 +Anaphase promoting complex 0.460712899052665 0.7929091938336954 0.4278307303996231 1.0 0.8320564094661519 11 Q9UJX6,Q96DE5,P30260,O60566,Q16763,Q9UJX3 6 +Er ubiquitin ligase complex 0.5280193702996632 0.791330745078996 0.4287510117404955 1.0 0.8320564094661519 6 Q9Y679,Q9UBV2,Q6NTF9 3 +Blood microparticle 0.4032811368009369 0.7794292576957164 0.4357268946038002 1.0 0.8368574477905605 18 P27105,P38435,Q08380 3 +Nuclear envelope 0.2878930304093478 0.767760129663475 0.4426297055958201 1.0 0.846482022453545 166 Q99720,O15173,Q96KC8,Q9H2V7,Q96RT1,P57740,Q9BZF3,Q03001,Q5BJF2,Q6NUM9,Q12981,O94901,Q9BTX1,Q9H1E5,Q9NQC3,Q9Y6K0,O15118,Q8WXH0,Q03252,P07437,Q8WWI1,O14681,Q8N1F7,Q96EE3,P80303,P50402,P41208,O76062,Q96AG4,O75844,P42167,Q9UI26,Q6ZRP7,Q92575,P67809,P20700,Q7Z3B4,Q5SNT2,Q14728 39 +Crd mediated mrna stability complex 0.5207487620856448 0.7595781396876214 0.4475067901087262 1.0 0.8485563075154872 6 P67809 1 +Spindle microtubule 0.3658568687190024 0.7477606469062837 0.4546045429260057 1.0 0.8511946985748433 30 O94927,P50748,Q9H6D7 3 +Acrosomal membrane 0.715439276485791 0.7195631794092567 0.4717939893873857 1.0 0.8620309641691146 2 P35613 1 +Hulc complex 0.7151162790697692 0.7184116468400792 0.47250350760541 1.0 0.8620309641691146 2 Q5VTR2 1 +Messenger ribonucleoprotein complex 0.5376039188691981 0.7163350653876948 0.4737844797828079 1.0 0.8620309641691146 5 P51991,Q9NUL3,P67809 3 +Platelet alpha granule 0.3951196534647766 0.7144450746274035 0.4749520081864695 1.0 0.8620309641691146 16 Q8NBX0,Q8NBM8 2 +Brisc complex 0.7131782945736431 0.7115140801340161 0.4767657287862701 1.0 0.8620309641691146 2 Q9NXR7 1 +Nuclear pore nuclear basket 0.4949051073360223 0.697967474926255 0.4851975348768029 1.0 0.8680848764047927 7 Q8NFH5,P41208 2 +Nuclear pore central transport channel 0.71669020899001 0.6967910861723212 0.4859335453394426 1.0 0.8680848764047927 3 Q7Z3B4 1 +Myosin filament 0.7083333333333353 0.6943591099774096 0.4874570301318732 1.0 0.869071796749057 2 P35580 1 +Apical plasma membrane 0.3667116050946669 0.6775230804809692 0.4980741311390297 1.0 0.8725247838583069 50 Q8WWI1,Q9Y6M7,P51790,P30825,Q13277,O75955,Q16625,O75787,P08183,P53985,P33527,P41440 12 +Copi vesicle coat 0.4578002039676931 0.6689027562352781 0.503557511895651 1.0 0.8734185526097048 9 Q8NDZ4 1 +Neurofilament 0.70630048465267 0.6625988333563682 0.5075875175694968 1.0 0.8748915082058121 3 P07196,P07197 2 +Presynaptic active zone 0.4160002992060798 0.6580635850336323 0.5104972739223042 1.0 0.8748915082058121 13 Q13277,O75955,P20020,P41440 4 +Cohesin complex 0.5224917664337556 0.65526186187492 0.5122991711709854 1.0 0.875014805721435 5 Q8N3U4 1 +Endoplasmic reticulum protein containing complex 0.3705354953887183 0.6374284113344298 0.5238458269454114 1.0 0.8786697512980642 64 Q03518,O43681,Q6NUQ1,Q96CS3,Q9P0I2,P04439,P67812,O15269,Q53GQ0,P49458,Q9NPA0,Q92643,Q9UGP8,P51571,Q15005,Q8WU17,Q9UBV2,Q9Y5M8,Q9Y679,Q8IXB1,P46977,Q6NTF9,P04843 23 +Nuclear envelope lumen 0.5578286566495252 0.608927031558911 0.5425728058803885 1.0 0.8906695915374269 4 P07437,Q9HB71 2 +Cell body membrane 0.6875605815832098 0.602205159330186 0.5470375818054585 1.0 0.8906695915374269 3 P20020,P23634 2 +Nuclear exosome rnase complex 0.4333514224705028 0.5999734978670357 0.5485238979660383 1.0 0.8906695915374269 10 Q5RKV6,Q13868,Q9NQT5,Q96B26 4 +Intrinsic component of mitochondrial outer membrane 0.3956528538163352 0.5913215605439079 0.5543049860182645 1.0 0.8906695915374269 14 O96008,Q8TB36,Q8IWA4,Q15388,Q9BWH2,P50416,Q9Y3D6 7 +Meiotic cohesin complex 0.5476734453271116 0.5724375290134477 0.5670255969974312 1.0 0.8998012576466328 4 Q8N3U4 1 +Golgi apparatus subcompartment 0.3662008610260748 0.5668491284242001 0.5708166891087452 1.0 0.9036379719476066 83 O43752,O00461,P0CG08,P35670,Q8N2H4,O15127,Q15363,Q9NPR9,Q9UP83,Q9Y5X1,Q9BSR8,P50570,P98194,Q4J6C6,P51572,Q9P260,Q9BXS4,O95249,Q9HC07,P83436,O60499,Q10713,Q9UNK0,P40616 24 +Secretory vesicle 0.3129239708365226 0.5658986596858834 0.571462672762397 1.0 0.9036379719476066 251 Q9H7Z7,P30519,O43681,P42785,P07602,O00584,Q9BTY2,P45880,Q9Y487,P27105,O43760,P51790,P50897,Q93050,P06865,Q9BT78,Q13510,Q99536,P12956,Q9NQX7,P16278,Q8NBM8,Q13277,Q9NUQ9,P42892,Q9UQB8,Q07065,P14174,P06280,O60499,Q5T9A4,Q9UI14,Q8NBX0 33 +Transport vesicle 0.3634957213449059 0.5632937873261025 0.5732348478988993 1.0 0.9048416029444708 93 O43752,Q9NRW7,O00461,O43760,Q15363,P24390,P50897,Q96A57,P51790,O15400,Q9BT78,P10321,O43731,Q9GZM5,Q13277,Q9Y3B3,P20020,O14653,O95249,Q9BVK6,O60499,Q9UI14 22 +Golgi transport complex 0.494540639824053 0.5455047446636953 0.58540641819223 1.0 0.9111978161426884 5 Q9UP83,P83436 2 +Trans golgi network 0.3588317474802614 0.5389470893811865 0.5899233638339434 1.0 0.9150457723247476 61 O43752,Q9NPR9,Q9UP83,P50570,P40616,Q4J6C6,P98194,Q9HC07,Q9Y5X1,P83436,Q8N2H4,P35670,O60499,Q9BSR8,O15127,Q9UNK0,Q9P260 17 +Derlin 1 retrotranslocation complex 0.4865987257878106 0.5152363689419972 0.6063878576143122 1.0 0.9292490542011624 5 Q8WU17 1 +Neuron projection membrane 0.4518193745046027 0.5101100660925328 0.6099743534427589 1.0 0.9300290397466254 7 P20020,O75787 2 +Platelet dense granule 0.6484652665589731 0.4825106579926676 0.6294432290167846 1.0 0.9373572212479572 3 Q08380,P13473 2 +Female pronucleus 0.5213457001734108 0.4809584053206428 0.630546061332877 1.0 0.9374397423470516 4 P83916 1 +Emc complex 0.4527611988520568 0.4744524717572362 0.6351772828486126 1.0 0.9398687023619068 6 Q9P0I2 1 +Ciliary membrane 0.4456662354463072 0.4464490345363154 0.6552729195691358 1.0 0.9560398379305128 6 O14936,Q96J42,P06744,Q9H4M9,Q15019 5 +Presynapse 0.3528518004166399 0.4337643996686672 0.664459535995169 1.0 0.9560398379305128 87 O43752,P07196,Q9NRW7,O75955,Q13641,O43760,P51790,P50897,Q96A57,O15400,Q9BT78,P50570,Q13277,P20020,Q9UQB8,Q9BVK6,O14976,O60499,Q9UI14,P41440 20 +Presynaptic active zone membrane 0.4642398699031704 0.4326780058900118 0.6652487103925233 1.0 0.9560398379305128 5 Q13277,P20020 2 +Cell surface 0.3524134668318228 0.4311770998249896 0.6663396036191664 1.0 0.9560398379305128 75 P02786,O96005,O75955,Q13641,P51790,Q8WTV0,Q08722,P10321,Q8WWI1,O43847,P08183,P42892,O75298,P06576,Q4VCS5,O75787,P00390,P14174,P41440 19 +Ciliary basal body 0.3677628315945219 0.4294090276597914 0.6676255851470061 1.0 0.9560398379305128 14 P41208 1 +Chitosome 0.619758757644894 0.4012052943634392 0.6882689831106652 1.0 0.9689360849657312 3 Q04656 1 +Spindle pole 0.3286907461497504 0.384576441787063 0.7005512509212235 1.0 0.971920386549798 44 Q8N3U4,Q9UJW0,P50748,Q96DB5,P52732,P50402,Q13432,P14635,Q9P287,Q5SNT2 10 +Microvillus membrane 0.489657401422109 0.3781003723929689 0.7053560316863228 1.0 0.9728921177896016 4 P35222,P06756,P15311 3 +Dna repair complex 0.3423159321262518 0.3779064775964361 0.7055000702514953 1.0 0.9728921177896016 17 P12956 1 +Secretory granule 0.2927756367354938 0.3675072248600251 0.7132407036609205 1.0 0.9790650763443618 227 Q9H7Z7,P30519,O43681,P42785,P07602,O00584,Q9BTY2,P45880,P27105,Q9Y487,P51790,Q93050,P06865,Q13510,Q99536,P12956,Q9NQX7,P16278,Q8NBM8,Q13277,Q9NUQ9,P42892,Q9UQB8,Q07065,P06280,Q5T9A4,Q8NBX0 27 +Recycling endosome membrane 0.3375747506940264 0.3577900814292447 0.7205004137632489 1.0 0.9852654069859208 21 P02786,O15126,P10321,P04439,O15127,Q9H4M9,O14828,Q15907 8 +Late endosome membrane 0.316730123039432 0.3433794052871636 0.731313050924117 1.0 0.9872174669337628 30 P51790,Q14108,Q9HC07,O15118,O14653 5 +Bcl 2 family protein complex 0.4769255416129344 0.3394276685542954 0.7342875779590321 1.0 0.988641229723462 4 Q07812,Q13794 2 +Apical part of cell 0.336430354978905 0.3371568961596156 0.7359986287142428 1.0 0.989067226275146 60 Q8WWI1,Q9Y6M7,P51790,P30825,Q13277,O75955,Q16625,P41208,O75787,P08183,P53985,P33527,P41440 13 +Protein lipid complex 0.4139899114996439 0.3273135362002433 0.7434307554082276 1.0 0.9915090888721136 6 Q9UHG3 1 +Cytoplasmic ubiquitin ligase complex 0.3835199045902333 0.3259493324297249 0.7444626901922462 1.0 0.9915090888721136 9 Q9Y679,Q9UBV2,Q6NTF9 3 +Tertiary granule membrane 0.3607491052116849 0.3183098330544585 0.7502499262230309 1.0 0.9937938926869346 12 P27105,Q4KMQ2,Q08722,O75787 4 +Side of membrane 0.3352420285294237 0.3056067507782402 0.7599040798751187 1.0 1.0 64 P02786,O96005,O75955,P04899,P51790,Q9Y5X1,O43464,P10321,Q14344,P51572,P08183,P20020,P18031,P42892,Q4VCS5,O75787,P63218,P10619,P00390,Q9NV70,Q9Y4F1,P41440 22 +Mmxd complex 0.5720284237726164 0.2859557384171583 0.7749120222003294 1.0 1.0 2 P05141 1 +Rna polymerase iii complex 0.4579831932773126 0.2851122237507962 0.7755581653559052 1.0 1.0 4 O15160,P19388,P62875 3 +Distal axon 0.3225383224037194 0.2820457982748286 0.7779083932566191 1.0 1.0 50 Q07866,Q99720,P51790,P50570,Q13277,P07196,Q13641 7 +Endoplasmic reticulum lumen 0.3307842666971679 0.2809314664513587 0.7787629653921861 1.0 1.0 61 O43681,Q5JRA6,Q02818,Q9UNW1,Q07065,Q9NZ08,Q14257,O00584,Q9BTY2,O43852,Q8IXB1,P04114,Q32P28,O75718,Q9NWM8 15 +Microtubule associated complex 0.3095898736645808 0.2800355031358748 0.7794502665711724 1.0 1.0 38 O94927,Q07866,Q9UJW0,O75935,Q13561,Q9H6D7 6 +Signal peptidase complex 0.5634614881960093 0.2620682223027924 0.7932688457066759 1.0 1.0 3 P67812 1 +Microbody lumen 0.3187448852983573 0.2425365774472421 0.8083644180255625 1.0 1.0 22 Q13011,P35914,O15254 3 +Centrosome 0.2980250360096038 0.2424608952674549 0.8084230540087427 1.0 1.0 137 Q03518,Q9UJW0,O75955,Q9P287,O94927,P04899,P14635,P53985,Q14145,Q9H6D7,Q8N1F7,P50570,P50402,P41208,Q13432,Q9Y5K8,Q6DKK2,P28074,O75935,P55081,P41440 21 +Risc loading complex 0.5513565891472947 0.2406616182844274 0.8098173888817948 1.0 1.0 2 O75569 1 +Nuclear stress granule 0.5513565891472884 0.240661618284414 0.8098173888818052 1.0 1.0 2 Q92797 1 +Protein kinase complex 0.3187984906607271 0.2386032900091252 0.8114132137493879 1.0 1.0 21 P14635,P12956 2 +Granular component 0.4402068519715596 0.237972256807347 0.8119026120012989 1.0 1.0 4 O75683,Q9NXV6,Q14684 3 +Tight junction 0.3137603348612913 0.2242858001943513 0.8225349245816487 1.0 1.0 24 Q9NR77,Q16625,Q4VCS5 3 +Paraspeckles 0.3796895213454006 0.2118091153486316 0.8322559568469836 1.0 1.0 6 Q8WXF1,Q15233,P23246,P52272,Q16630 5 +Anchored component of membrane 0.3774256144889969 0.2047706056358455 0.8377513536613448 1.0 1.0 6 P61020,P36551,P51149,P13591,Q15286 5 +Gamma secretase complex 0.5316537467700345 0.2024206592087605 0.8395878789697051 1.0 1.0 2 P49755 1 +Dendrite terminus 0.5253634894991848 0.1858323937894876 0.852576200408375 1.0 1.0 3 Q7L576,P08238 2 +Dendritic growth cone 0.5253634894991848 0.1858323937894876 0.852576200408375 1.0 1.0 3 Q7L576,P08238 2 +Transport vesicle membrane 0.3038010153108039 0.1858008239575555 0.8526009583601226 1.0 1.0 43 Q15363,O43752,Q15907,O15126,O75396,P10321,Q9Y3B3,P04439,Q13190,P20020,O60499,O14653,O43760 13 +Pigment granule 0.3210818961398148 0.1794199169672105 0.8576079936552439 1.0 1.0 64 P02786,P61019,O75955,P27105,Q93050,Q15758,O75396,Q14344,P50991,Q04656,Q13637,Q13277,O43852,P30040,P55209,P35613,O14773,P41440,P04843 19 +Site of polarized growth 0.3004489817465237 0.1775020935502181 0.8591140209297707 1.0 1.0 41 Q07866,Q99720,P50570,Q13277,P07196 5 +Mitotic cohesin complex 0.512919896640834 0.1706024623899548 0.8645363616060282 1.0 1.0 2 Q9UQE7 1 +Ciliary base 0.3641655886157785 0.1651571235132456 0.8688203122221625 1.0 1.0 6 P13861,P61006,P17252,Q8TD19,A0AVF1 5 +Xy body 0.4062702003878491 0.1593678441495358 0.873379071746663 1.0 1.0 4 Q56NI9,Q92922,Q12824 3 +Cytoplasmic exosome rnase complex 0.3301819804785904 0.1538776378915702 0.8777062164615321 1.0 1.0 11 Q5RKV6,Q9NQT5,Q96B26 3 +Endoplasmic reticulum plasma membrane contact site 0.4996770025839854 0.1507712219380022 0.8801561882847571 1.0 1.0 2 Q9NTJ5 1 +Microtubule end 0.3379734541922907 0.1483088481104082 0.8820990328007738 1.0 1.0 9 Q14008,Q15555,Q7Z460,Q14203,Q99661,Q86Y91,Q03001,Q15691 8 +Microtubule plus end 0.3379734541922907 0.1483088481104082 0.8820990328007738 1.0 1.0 9 Q14008,Q15555,Q7Z460,Q14203,Q99661,Q86Y91,Q03001,Q15691 8 +Cd95 death inducing signaling complex 0.4961240310077578 0.1458206179227084 0.8840629991321174 1.0 1.0 2 Q9UNN5 1 +Brush border membrane 0.3361931116701263 0.1421001666786518 0.8870008865226016 1.0 1.0 9 Q14344,Q14728,P41440 3 +Sperm midpiece 0.3683615640019314 0.1420427868079113 0.887046209315155 1.0 1.0 5 Q15388 1 +Nucleoid 0.2857916363021914 0.1336440442999191 0.893684054255903 1.0 1.0 34 P21796 1 +Gamma tubulin complex 0.4865912762520105 0.1245375206210449 0.9008896944452518 1.0 1.0 3 Q9BSJ2,Q96CW5 2 +Secretory granule membrane 0.3187056026263913 0.1165201714592637 0.9072403004707804 1.0 1.0 74 P30519,P42785,Q4KMQ2,P07602,Q9NZJ7,P27105,O00264,Q15363,Q93050,Q08722,P10321,Q9NQX7,Q13277,Q9Y5K8,Q6IAA8,Q07065,P10253,O75787,Q5T9A4 19 +Mitochondrion 0.3323162326887001 0.1088378120712729 0.9133311322517452 1.0 1.0 648 Q9H7Z7,P00846,Q99595,O60830,Q9NPH0,Q9HCL2,P21796,Q567V2,P45880,Q70HW3,P03886,Q9Y584,O43169,Q16740,O43676,Q9H061,P14406,Q9UDX5,Q9NS69,Q69YU5,O75964,Q9H6K4,P62072,Q13423,Q13505,O43772,Q8N4H5,Q8WY22,P09601,Q9UMX5,Q9UDW1,Q15165,Q13011,Q6P4A7,P22830,Q9NR77,Q08J23,Q9BSK2,Q9P0J0,Q8NBX0,Q8TBP6,Q9NUJ1,Q9BWD1,Q96A26,Q96NB2,Q9UL15,O00584,O95831,P27105,Q3SXM5,Q9HA77,Q7KZN9,Q9Y2R0,Q9BQT8,Q99536,Q9UBX3,Q96H78,Q53H12,Q5XKP0,P13073,Q8N163,Q9H3P7,P22695,P35914,Q9NUQ9,P20674,Q6DKK2,O75431,Q13794,O96000,O95202,P23786,O43819,Q96TA2,Q5T9A4,Q10713,P30837,Q15070,O95182,Q9H2V7,P00403,Q12981,Q8NFF5,Q9UJS0,Q86VD7,O14949,Q9UJZ1,Q9H773,P14635,P28070,Q15388,Q9NQ88,Q6YN16,Q9Y619,Q9P0S9,O95168,P51572,Q9NVT9,O00203,O75746,Q9Y277,P50416,Q9Y6C9,P16435,Q9BUK6,Q9H2D1,P06576 107 +Cell pole 0.4723747980613846 0.1062033041358397 0.9154210494540752 1.0 1.0 3 P35241,P08195 2 +Anchored component of synaptic vesicle membrane 0.3771816418875259 0.1047836042681574 0.9165475203203064 1.0 1.0 4 Q15286,P51149,P61020 3 +Nuclear inclusion body 0.3284789644013011 0.104778465956679 0.9165515976554912 1.0 1.0 8 Q9UBU9,P52948,Q86U42,P12270,O60934,P49792,P49790 7 +Torc1 complex 0.4541343669250631 0.0986045408788662 0.9214522644948246 1.0 1.0 2 Q9Y4R8 1 +Tor complex 0.4541343669250631 0.0986045408788662 0.9214522644948246 1.0 1.0 2 Q9Y4R8 1 +Proton transporting atp synthase complex catalytic core f 1 0.3731465618254135 0.098170014319428 0.9217972925319105 1.0 1.0 4 P06576,P25705 2 +Lumenal side of membrane 0.3218498020303044 0.0944142326575149 0.9247801102826784 1.0 1.0 9 P10619,P51572,P10321 3 +Aryl hydrocarbon receptor complex 0.4437984496124168 0.08995686394576 0.9283214933785162 1.0 1.0 2 P08238 1 +Extrinsic component of synaptic membrane 0.3400815690922288 0.0821197925417041 0.9345514541082184 1.0 1.0 5 Q9Y4F1 1 +Immunological synapse 0.3106891113262408 0.0805569554782704 0.9357942994490502 1.0 1.0 11 Q9UJZ1,O15400 2 +Vcp npl4 ufd1 aaa atpase complex 0.3600517129928916 0.0783077366633422 0.9375832633959328 1.0 1.0 4 Q96CS3,Q92890,Q9UNN5 3 +Synaptic membrane 0.2820685445523002 0.0762643550833114 0.9392087837472808 1.0 1.0 37 Q99720,P51790,P50570,Q13277,O75787,P20020,Q9Y4F1,Q15375,P52292,Q9UQB8 10 +Exoribonuclease complex 0.29216614459833 0.0758024233075136 0.939576288153805 1.0 1.0 15 Q5RKV6,Q13868,Q9NQT5,Q96B26 4 +Pronucleus 0.3331753416513933 0.0695156329993514 0.9445791894212644 1.0 1.0 5 P83916 1 +Extrinsic component of mitochondrial inner membrane 0.4244679210400456 0.0597540507107932 0.952351522363023 1.0 1.0 3 Q96BW9 1 +Sodium potassium exchanging atpase complex 0.4177705977382899 0.0549882388295103 0.9561478336710773 1.0 1.0 3 P54709,P05023 2 +Cation transporting atpase complex 0.4177705977382899 0.0549882388295103 0.9561478336710773 1.0 1.0 3 P54709,P05023 2 +Lumenal side of endoplasmic reticulum membrane 0.3174622077183464 0.0496854582077948 0.9603730448158304 1.0 1.0 6 P51572,P10321 2 +Protein phosphatase type 2a complex 0.3210475266731308 0.0493138469554576 0.9606691846694164 1.0 1.0 5 Q14738,Q15257,P63151,P30153 4 +Zona pellucida receptor complex 0.3187843517620365 0.0458145137893856 0.9634580906269784 1.0 1.0 5 P49368,P50991,P78371,P17987 4 +Intrinsic component of postsynaptic specialization membrane 0.3922425817571089 0.0401681515609913 0.9679590685009274 1.0 1.0 3 Q15375 1 +Ubiquitin conjugating enzyme complex 0.3280542986425362 0.0397426742518559 0.9682982794021278 1.0 1.0 4 P61088,Q5VTR2,O75150 3 +Dynein complex 0.3037927106145646 0.0362609694726023 0.9710742713074456 1.0 1.0 8 Q9UJW0 1 +Carboxy terminal domain protein kinase complex 0.3802907915993487 0.0348622279535224 0.9721896000186268 1.0 1.0 3 P50750,Q96T76 2 +Postsynaptic endosome 0.3770597738287584 0.033586790252388 0.9732066561776778 1.0 1.0 3 P20338,Q86Y82 2 +9plus0 non motile cilium 0.311052568492235 0.0335476958747436 0.9732378314095648 1.0 1.0 7 P35613,P41208 2 +Intraciliary transport particle b 0.3418416801292426 0.023386467714961 0.9813419992543504 1.0 1.0 3 Q8WYA0,A0AVF1 2 +Intraciliary transport particle 0.3418416801292426 0.023386467714961 0.9813419992543504 1.0 1.0 3 Q8WYA0,A0AVF1 2 +Oxidoreductase complex 0.3036614570627164 0.0228078814732374 0.9818035211546284 1.0 1.0 66 O43676,O96000,O95182,P22695,Q9UDW1,O14949,P03886,Q9P0J0,O43169 9 +Gemini of coiled bodies 0.3016488845780763 0.0220213867356369 0.9824308955255444 1.0 1.0 5 Q16637,Q8TEQ6,P57678,O75312 4 +T tubule 0.2979342108242996 0.0219165268048158 0.9825145414576896 1.0 1.0 8 Q12955,P23634,O75298 3 +Prefoldin complex 0.3071066385897544 0.0215742584713907 0.9827875675157796 1.0 1.0 4 O60925 1 +Calcium channel complex 0.302393272962481 0.0209764870905168 0.9832644121323292 1.0 1.0 6 Q8IYU8,P54652,Q15257,Q8NE86,P17252 5 +Uniplex complex 0.3021001615508927 0.0178198788365659 0.985782546259102 1.0 1.0 3 Q8IYU8,Q8NE86 2 +Main axon 0.2821763420861221 0.0062054634319006 0.9950487883117722 1.0 1.0 4 Q12955 1 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ada30f63a1520f059d04ab8dbd16fa42c5949d61 --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atp binding cassette abc transporter complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Calyx of held", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Chylomicron", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna recombinase mediator complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Muscle myosin complex", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class i", "Phosphatidylinositol 3 kinase complex class ia", "Phosphatidylinositol 3 kinase complex class iii", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Serine type endopeptidase complex", "Serine type peptidase complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilium bundle", "Stereocilium membrane", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquinone biosynthesis complex", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPGK", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C12orf73", "C14orf2", "C17orf75", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C3orf58", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARS2", "CASK", "CAST", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC22", "CCDC47", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPI", "CENPL", "CENPP", "CENPQ", "CENPU", "CENPV", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CISD3", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLTB", "CLTC", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DOLK", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP3", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM162A", "FAM207A", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP4", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMC1", "FMR1", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCX", "GGH", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD5", "HDLBP", "HEATR1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOXD11", "HP1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ISCU", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "IVD", "JAGN1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LETMD1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "M6PR", "MACF1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL7B", "METTL9", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD8", "MGAT1", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NEPRO", "NES", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPM1", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C3A", "NTHL1", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT12", "NUDT19", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAK1IP1", "PAK4", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PECR", "PEDS1", "PEF1", "PELP1", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHIP", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRSS3", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPS1", "ROMO1", "RP2", "RPA1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSRC1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT2", "SIGMAR1", "SIN3A", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35A4", "SLC35B2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPNS1", "SPOP", "SPOUT1", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM29", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TKT", "TLE3", "TLN1", "TM7SF2", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM214", "TMEM223", "TMEM230", "TMEM33", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBIAD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "USMG5", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP3", "XPO1", "XPO5", 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sha256:e210b9c3bcf2c444ddd3478e73b4c2a8388bca25dada056407f05b4626e87b78 +size 146566 diff --git a/msigdb_gomf/basic/plot_9.png b/msigdb_gomf/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..c360b07a988e4337deece9c65df66dbb0ea31f37 --- /dev/null +++ b/msigdb_gomf/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:352b1b776ac91dfc8417de61c97a4742d53ff93322b48ea6a3b3fce9e2bc021f +size 148602 diff --git a/msigdb_gomf/consensus.joblib b/msigdb_gomf/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..743aa8bc6b602b3190fe3aa39ce159e81b8b2da1 --- /dev/null +++ b/msigdb_gomf/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:64486f061e7ae38ff852607bf7aa8ce8acf621cfb1203541b455c9775d101747 +size 178952 diff --git a/msigdb_gomf/df_merge.tsv b/msigdb_gomf/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bfc2a87651a3206e79e1ca2d7d269452f983bf50 --- /dev/null +++ b/msigdb_gomf/df_merge.tsv @@ -0,0 +1,63 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transporter activity 82 191 5.240589503637242 1.60064427570859e-07 62.22330097087379 172.27912621359224 2.173366592838491 0.2707201784543502 25.984753572620328 19.29276868436311 2.593156143256053 0.3916539604106395 4.322840297291986e-13 1.1376344209915652e-10 1.4061731172322598e-11 3.775007312184107e-16 1.442544663723396e-17 +Ion transmembrane transporter activity 50 114 3.413562467926932 0.0006411945726332 37.34466019417476 101.497572815534 2.0154097423383375 0.2561362875319209 17.172953606300336 11.579295798802024 2.277787478419462 0.3756175790939143 3.668526995361594e-07 0.0001014875693383 8.701132629491677e-06 3.573247043969967e-10 7.629082523318636e-12 +Molecular transducer activity 14 32 3.37263334803084 0.0007445302453292 10.91747572815534 33.40533980582524 1.343848990749489 0.2329582295822712 4.7124072380860955 5.830391636254363 1.6098335072319665 0.2956883791113679 0.1587860322479854 0.1266598994577792 0.1059311237939693 0.2883362816761057 0.2718601126184135 +Proton transmembrane transporter activity 13 38 3.269213292617948 0.0010784697155352 12.769417475728156 35.478155339805824 1.2352045534927034 0.2879171268332734 5.319202861157036 2.7149368379617917 1.7021108079122016 0.3308025072902738 0.000275470700349 0.0004231087345942 7.821856645482414e-05 1.466381635734091e-06 2.0440750709764312e-06 +Alcohol binding 4 14 3.227652672895303 0.0012481041790781 5.70873786407767 16.094660194174757 1.0972550148478282 0.1642412137618775 2.3364194162363723 2.1334758164294443 1.72577974721897 0.2306417307890987 0.0016364756054694 9.216009865795702e-05 0.0001168596637319 0.006984722202598 0.0099411678564375 +Cholesterol binding 4 12 3.1196267812699574 0.0018108031578683 5.25 13.29126213592233 1.1679703080780182 0.1357521674166823 1.9454015982929531 1.7674569958716484 1.7544522374432017 0.2116991383290636 0.0001453810823637 1.176895700182785e-05 9.164358234292652e-06 0.0006954184772239 0.0027845492980534 +Steroid binding 6 19 3.109864955517698 0.0018717289750063 8.424757281553399 21.398058252427184 1.4469817519716153 0.1523451695819165 3.035656818503787 2.066091501771892 1.85140774519605 0.2395996334984524 0.0001835239930408 8.508689216563006e-05 0.0001059830796752 0.000162079776431 0.0022658484440293 +Sterol binding 4 14 3.0941796948993754 0.0019735791151604 5.495145631067961 16.27912621359223 1.1610523788441311 0.1592175050218891 2.159304933149918 1.9111962434971217 1.7231989277496158 0.231586711794193 0.0003537187819423 2.476611897309206e-05 2.315121590530167e-05 0.0016346598494465 0.0071436537580251 +Tetrapyrrole binding 9 18 3.0279298438072284 0.0024623524519502 7.402912621359223 16.83252427184466 2.0044897428967667 0.1259264696495541 2.9589081005845346 2.0417036568087963 1.3464702305086589 0.2177422235164347 3.621605479309189e-05 0.0001247827123008 1.2749630407991343e-05 4.204252026569053e-05 0.0002308677663279 +Protein transporter activity 6 16 2.964235538916327 0.003034359338192 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 5.812529742110397e-05 5.529301980218187e-06 3.550681930302554e-06 0.0002861885476851 0.000136356004925 +Cation transmembrane transporter activity 31 79 2.913161569558292 0.0035778942756055 25.62135922330097 70.51699029126213 1.766742880952279 0.2698419237572138 12.29126021871486 8.422243011776631 2.00238274385689 0.3706372466673562 0.0006547304778587 0.0048423585336687 7.829658362857708e-05 3.2067790707302085e-06 6.892561605705229e-06 +Gated channel activity 4 14 2.8893974998396623 0.0038598081869467 4.317961165048544 13.019417475728156 0.8697524591818097 0.2583579989367679 2.2914716766946497 2.0107989163575497 1.3733766112751231 0.2762671399351702 0.0036733807920826 0.0029449884503582 0.0203848430395501 0.0148252690690975 0.0698685551762488 +Passive transmembrane transporter activity 6 37 2.8862012611800982 0.0038992272336746 10.728155339805824 34.00242718446602 0.8598494327527568 0.3171523987434088 5.464704354730218 4.259483301090722 1.5882390061019254 0.3339692919660049 0.0035419377076125 0.0002061120351411 0.0049705397344002 0.020682535454445 0.1020793726789788 +Organic anion transmembrane transporter activity 17 35 2.881604441938753 0.0039565608506224 12.951456310679612 30.182038834951456 1.56101282472555 0.2452312368187786 6.880574373146614 3.5222410835885483 1.575669523214114 0.314839840161206 0.1812354162151875 1.0 1.0 0.0044585204680354 9.640650611383104e-08 +Anion transmembrane transporter activity 28 53 2.799066280155896 0.0051250616266498 18.594660194174757 45.61893203883495 1.6222323024349488 0.2373683627198559 9.346785472607134 6.017202751823004 1.8117646078257517 0.3183345645365742 0.0003234256282767 0.022467997482696 0.1237100881146933 1.084202640355499e-05 1.301346043430078e-09 +Snap receptor activity 10 15 2.777328157875988 0.0054807812823316 5.803398058252427 13.6626213592233 0.8920027438628428 0.3386294703372389 3.103034547770364 2.9171839264116786 1.2201519782198902 0.3219991979242683 0.4473276103609814 1.0 1.0 0.0088087297166582 2.4597593044142757e-05 +Inorganic molecular entity transmembrane transporter activity 22 85 2.6710570079179985 0.0075612803961013 28.058252427184467 75.9635922330097 1.5031303400189615 0.2894264293069549 11.721339963426631 9.38477049228959 2.153051736566399 0.3821536813265525 7.846473340315444e-05 0.0001464830842006 2.2296295606704816e-05 4.226563383590105e-07 6.4309312212679455e-06 +Hydrolase activity acting on glycosyl bonds 8 26 2.649441913862639 0.0080624830377198 10.133495145631068 28.40776699029126 0.6089784953463463 0.2409908190925149 3.36301188653944 3.2424277527979313 1.935823411407979 0.3010513017078077 4.167766305407689e-06 1.0 0.0054554424478239 6.238783903159406e-05 0.0085099687642093 +Organic acid transmembrane transporter activity 14 23 2.62943888659538 0.0085525902700656 8.592233009708737 21.276699029126213 1.5973629153049684 0.1905568538747131 4.4420473133518055 2.549726956007885 1.3213968531498468 0.2647933566957936 0.0297195507119602 1.0 0.4860789703868964 0.0002231001666191 6.508929388004252e-07 +Anion channel activity 4 13 2.583211415627623 0.0097885319530592 4.20873786407767 11.21116504854369 1.03959259790327 0.2192420598609839 2.3076742714116403 2.0905640066649145 1.3937691950814175 0.2662450395835827 0.0001031035620576 0.0003140311505353 0.0024390672757694 0.0004989114687539 0.001918269568256 +Macromolecule transmembrane transporter activity 5 13 2.5761909372353182 0.0099895466093342 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 0.0003348720906127 2.1554990909934077e-06 3.5959740301631905e-05 0.0011993766429203 0.0002747300414667 +Hydrolase activity hydrolyzing o glycosyl compounds 7 19 2.5750588501582654 0.0100223032375768 8.830097087378642 20.84223300970874 0.5983257656540719 0.2104301479001341 3.2223833352824554 2.4557961681485057 1.9540573665272416 0.2728112677124137 1.4077128092826385e-06 1.0 0.0111977735740575 1.7283935081196885e-05 0.0019780921583714 +Monooxygenase activity 7 8 2.5733186917900137 0.010072840798843 4.043689320388349 8.322815533980583 1.6049222537693364 0.1501440468766332 1.612461779657682 1.2307404965531048 1.237349324058907 0.2369071661653372 0.0109086979057498 0.1221118561195742 0.0021930786590517 0.0038040834633598 2.855045826118248e-05 +Phosphatidylcholine binding 2 7 2.5712248828783992 0.0101339497729693 2.2524271844660193 7.929611650485437 1.2697801287388335 0.1567893034984199 1.081337239384838 1.04388968498945 1.4953842980517238 0.2256102823610289 0.0023996235659409 5.590323461425328e-05 0.000453663444764 0.0062267265321947 0.0397387250697101 +Protein transmembrane transporter activity 5 12 2.557507279502664 0.0105425351406451 4.37621359223301 11.264563106796116 1.6409152716253632 0.1284874270119089 2.3258190399954897 0.995332092405782 1.387057072324357 0.2266762256512647 0.0001712958304139 1.070130773077186e-06 1.806422085995589e-05 0.00062382482254 9.937036022358197e-05 +Sphingolipid binding 3 8 2.506496712805084 0.0121934191475234 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 0.0002172834510808 0.0032958763634803 0.012905013470629 0.0007869115437374 0.0097510399506001 +Active transmembrane transporter activity 35 86 2.4794832940565703 0.0131572893421709 26.354368932038835 73.12621359223301 1.313035419122872 0.3239574057550545 11.878456281473593 8.663537710607383 1.88741562841277 0.3851687956916088 0.0026147433359047 0.2533252671947448 0.0137108103615842 1.876730627042721e-06 1.000940533128907e-08 +Voltage gated channel activity 4 11 2.452145453148894 0.0142007246265334 3.2257281553398056 10.116504854368932 0.8578192560085278 0.2690365421745596 1.8168622808181427 1.411127559025233 1.234834479111217 0.2694186191218866 0.0026557537163926 0.0115082778780227 0.0428134756181982 0.0088087297166582 0.0229507437408614 +Oxidoreduction driven active transmembrane transporter activity 10 33 2.4414123001380283 0.0146299412710775 9.733009708737864 29.83252427184466 0.7626445826297276 0.3795490924215395 4.629116134249794 3.4519743101246267 1.4198222355288384 0.35536187545778 0.0220274882585249 0.0356328568827733 0.0222198796395938 0.0001156252433491 0.0001690300981766 +Active ion transmembrane transporter activity 19 48 2.420154864113807 0.0155138985177623 16.271844660194176 41.71116504854369 1.2957221273899948 0.3267733012969381 7.788084220174416 5.097264791179653 1.6571109350293016 0.3632481416270505 0.053381603202757 1.0 0.1070377409089595 0.0005710631251204 5.169265078828557e-05 +Quaternary ammonium group binding 2 11 2.3995553207921394 0.0164149992441859 2.8567961165048543 12.12864077669903 0.9707568143407772 0.2573327609820879 1.4849985868988949 1.260087490061347 1.304146106648176 0.2795917987269193 0.0061166095761946 0.0001506452861526 0.0011959433226113 0.0153906222854723 0.0200033311952484 +Metalloendopeptidase activity 4 14 2.380880599956839 0.0172713090593472 5.449029126213592 14.364077669902912 1.4597326207035937 0.2246869419023046 2.4848715129851016 0.6671711573432166 0.9390012824303952 0.2775881383017788 0.1105465258987554 1.0 0.0405463165390607 0.007920049564759 0.0045924061823516 +Exogenous protein binding 2 18 2.3740808621562297 0.0175926972241349 4.509708737864078 15.157766990291265 0.7214109752050332 0.2527966464979699 2.499010078306418 1.9009100692398744 1.5211756979359785 0.2791170769282048 0.042285212020163 0.0196403757049561 0.0093807730237194 0.0949405615621671 0.1732034237667374 +Ceramide binding 3 6 2.3596517190924837 0.0182920993155055 2.8228155339805827 5.048543689320389 1.42330045764979 0.1242195400491618 1.17628831869178 0.9309003969609838 1.481980135982154 0.2133994029014766 5.432060717638784e-05 0.0017062060788896 0.0067896670197663 0.0002022933287296 0.0027630263410089 +Amino acid transmembrane transporter activity 6 10 2.313283025982238 0.0207070833107876 4.325242718446602 10.521844660194176 0.9562493229862624 0.2921494362491497 2.574340086864074 1.34633933573134 1.106576767449958 0.2884960270895668 0.502342340158651 1.0 1.0 0.0720513532108381 0.0028137185393519 +Secondary active transmembrane transporter activity 9 25 2.3099613828289645 0.02089029218689 9.080097087378642 21.490291262135923 1.2627683473613005 0.2947710034053126 5.466215032972134 3.0675886156990426 1.4241587428281404 0.3340388164945335 0.4507547556737884 1.0 1.0 0.0197765739168328 0.0265567637490863 +Atpase coupled transmembrane transporter activity 16 29 2.3087867545154817 0.0209554173919985 8.072815533980583 22.696601941747577 0.8561067713091313 0.3392846662603397 4.166386392056555 3.892074110340729 1.3163009809214623 0.3229730128136945 0.0176600324030677 1.0 0.0186371594327644 0.0515621560092188 9.026170863058632e-05 +Inorganic anion transmembrane transporter activity 12 23 2.265743847384764 0.0234670712186839 7.427184466019417 19.274271844660195 1.0921593405593897 0.2441056926448881 3.717191605498929 3.7816647851785734 1.4014196343960104 0.2816216967014333 0.0002560032570095 0.0019537982219709 0.0139156518076104 3.17049669247141e-05 0.0001665225081846 +Vitamin transmembrane transporter activity 4 9 2.254122187334926 0.0241884822223448 2.7766990291262137 6.252427184466019 1.4438342367310928 0.182339474606115 1.52603324115363 1.3650879028699858 1.0282691527982806 0.2346378729908682 0.2818884584435067 1.0 1.0 0.0762921742488627 0.0118865434534573 +Sulfur compound transmembrane transporter activity 4 8 2.2540858310300127 0.0241907688631528 2.9635922330097086 6.752427184466019 1.4746434057995097 0.1672652154050841 1.7026919602194592 1.5538455059459366 1.0954441166028872 0.2266277553273111 0.3968926535471839 0.1305522111527444 0.2467424796819782 0.1552222190730896 0.0119362160344991 +Primary active transmembrane transporter activity 25 62 2.2527218601367656 0.0242766917317229 17.696601941747574 52.529126213592235 1.0080198242353189 0.3544097082146772 7.649017203625277 6.455721193615876 1.66885648871365 0.3767837436492733 0.0010931499781394 0.1131277718078383 0.0010779549165811 3.2521513425213215e-05 5.8196789450259134e-08 +Exopeptidase activity 9 30 2.235241997899678 0.0254014656587746 9.74514563106796 31.84223300970874 1.193034763402526 0.2308543476384821 3.0338864063053523 1.9513159274241312 1.6646797512653713 0.2911825093455628 0.0039465134692328 0.0345877004093447 0.0028574061260132 1.4349197272756235e-05 2.9640015944659375e-05 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 3 14 2.226827100086703 0.0259588314640899 3.8398058252427183 12.78883495145631 0.8288316105774708 0.2715528044153261 1.786836430207192 1.277729935586139 1.1940635938633195 0.228034100916913 0.0069459336161985 0.1049896535105009 0.0206800818926893 0.0020705519968491 0.0233101974365333 +Palmitoyl protein hydrolase activity 2 5 2.199421100508843 0.0278479936378039 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0009918498188417 0.0014481500629001 0.0057815105752346 0.00262770885776 0.018020673376298 +Modified amino acid binding 3 21 2.192185171820005 0.0283661387122127 4.446601941747573 21.354368932038835 0.8157790161756342 0.4133026066112408 2.099367243274066 1.7995833767593454 0.9656025978141096 0.3166170247143811 0.0092456434158216 0.0015498180404582 0.0111977735740575 0.0284489140367958 0.2029818831286367 +Voltage gated anion channel activity 4 7 2.191609634606814 0.0284077056661549 2.854368932038835 6.25 1.127126362633441 0.1649553590552043 1.5417035527207152 0.9966570336472054 1.4583344406160936 0.2334940994157564 1.6615978205831535e-05 0.0009934566258862 0.0039921150854813 6.292953854873037e-05 5.436360967141595e-05 +Oxidoreductase activity acting on a heme group of donors 4 7 2.1730711605471784 0.0297749618847866 3.111650485436894 6.483009708737864 0.8850005512180296 0.2757097651603665 1.538237610319269 1.0226572421183926 1.2777814224392188 0.2966482201944345 1.0 1.0 1.0 0.0051503840765812 0.0005289198821125 +Metallopeptidase activity 14 37 2.17238869957226 0.0298263566534802 11.548543689320388 40.60436893203884 1.2053444242445344 0.3510417366391842 4.586289489033314 2.1135899474190585 1.0988837346562612 0.3462572593421246 0.0493427227438463 1.0 0.0426450873703444 0.0006818386753638 2.640935012227938e-05 +Thiolester hydrolase activity 3 16 2.1521227175773334 0.0313876903395868 3.5388349514563107 15.259708737864075 0.4632661556505638 0.4260334035866009 2.4217755265330267 1.4839032472520584 1.039719510457206 0.2990167148437984 0.015943639086226 0.0096266028600564 0.0361556764775263 0.0383377547470353 0.0157766780310383 +Cargo receptor activity 5 7 2.145050956213789 0.0319487730592793 3.7063106796116503 7.95873786407767 0.9623237890522576 0.1578680760704802 1.9530058934839476 1.7914972745396005 1.6202205206532496 0.203966946010782 0.0120652542122147 0.0078974776787256 0.0024390672757694 0.0294507732567689 0.010278445998416 +Amide transmembrane transporter activity 4 7 2.1429706581178767 0.0321154545254886 1.9781553398058251 4.745145631067961 1.408683964326367 0.195466717632665 1.3391087077639925 1.811666809674734 1.0002201259794938 0.2223338014085611 0.0459284510874455 1.0 1.0 0.0834574734746242 0.00223229240551 +O acyltransferase activity 5 16 2.1155687014924154 0.0343815061275205 4.711165048543689 12.395631067961164 0.9877600518928406 0.2684789023147002 2.6842893514436073 2.3496085895491885 1.2379749168209273 0.2720543739153138 0.1049906211400749 0.1430638950507344 0.0383266740374144 0.0415700360883472 0.003914644875648 +Proton transporting atp synthase activity rotational mechanism 1 12 2.112371230049632 0.0346546206543147 3.655339805825242 10.75485436893204 0.46898650441807 0.3141755537304957 2.268964442606705 0.8649601417133376 1.3429609354721883 0.2856466957651606 0.0303360476395803 0.0026008925831016 0.0102498345034834 0.0561137872346343 0.0397387250697101 +Proton channel activity 1 12 2.112371230049632 0.0346546206543147 3.655339805825242 10.75485436893204 0.46898650441807 0.3141755537304957 2.268964442606705 0.8649601417133376 1.3429609354721883 0.2856466957651606 0.0339972376759384 0.0029386578360865 0.0115435449528709 0.062605312422627 0.0465653262864464 +Dicarboxylic acid transmembrane transporter activity 5 8 2.0992626865431285 0.0357937507528609 2.842233009708738 7.20873786407767 1.0708946030323223 0.2426579907451208 1.9772646753006824 0.7975212565102757 1.0844681659651012 0.2564515003952125 0.0303360476395803 1.0 1.0 0.0062267265321947 6.703246650942136e-05 +Proline rich region binding 1 6 2.090599624601952 0.0365639694390873 1.1529126213592231 5.186893203883495 0.8836697013404169 0.3769016216180994 1.161024096877417 0.956085799787736 0.8816524975681769 0.2959695633458655 0.0303360476395803 1.0 0.144637307685789 0.0561137872346343 0.1807018090276839 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 10 28 2.0544649349045225 0.0399307138411779 9.395631067961164 29.8373786407767 1.5709767518568172 0.2393367467664754 3.119976403291062 3.762391942431812 1.2135099906711824 0.3124947384976632 0.2166257128109771 0.3624074851394556 0.0616304522136525 0.1885836684813616 0.0052453150917069 +Lysophospholipase activity 1 7 2.0101361850029296 0.0444167772210957 1.4975728155339805 5.643203883495145 0.4872810977348831 0.3927962797845155 1.3228734288568833 1.2852325644953473 1.0735295231113575 0.2871232457524404 0.0174535696320652 1.0 0.1105474823156849 0.0328731354880699 0.1125747569923622 +Nucleobase containing compound transmembrane transporter activity 8 17 2.0008585944947423 0.04540763077157 6.529126213592233 14.04126213592233 1.4296604886183193 0.212054291115069 3.2696940585469636 1.915888183904924 1.3255809572534116 0.2748813593420038 0.1049906211400749 1.0 1.0 0.181169408752189 0.003914644875648 +Serine type carboxypeptidase activity 4 5 1.9906874736096856 0.0465152567015689 3.0558252427184467 4.997572815533981 1.0019911760482532 0.1105835516254352 1.1231414198895626 0.0492066381861973 1.8086551291944464 0.1930654928989846 0.0028631449281781 0.0002241871259369 0.0009157120850054 0.0001354907423541 2.6454681464607386e-07 +Metal ion transmembrane transporter activity 14 27 1.97129345730606 0.0486903192984922 9.563106796116504 24.67233009708738 0.8657396859235934 0.3700615753207195 4.93288923178502 4.839352380624028 1.4450904591933955 0.3424002804304004 0.6260674201758081 1.0 0.3324986857099054 0.1740979244634158 0.380844976353619 +Peptide binding 12 67 1.95997659493078 0.0499985259878834 17.133495145631066 70.30339805825243 1.21997288878307 0.3503559587509399 5.621054768990946 6.443005397350486 1.219878183292811 0.3773673755377006 0.0002249883219332 0.0053139908161637 0.0005525090849858 5.632581431164576e-05 0.0020342884965043 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f632d77b0647564578ca5d5627f1c1e556d4ceec --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 1362, + "title": "Average number of proteins per term", + "value": 16.071953010279003 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a314e9fd6eadb493abb567f5fbabfb75e6f98a95 --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..82faa058fcba17491ef33db3908951c2349fafcc --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,344 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter activity 0.5923176436083342 5.240589503637242 1.60064427570859e-07 0.0002179840058339 0.0002180077503528 191 P00846,O75306,O14678,Q4KMQ2,Q99595,O60830,P35670,P21796,P45880,Q70HW3,Q9BZF3,P03886,Q9Y584,Q9Y487,Q9C0H2,O43808,O14925,O43676,Q8WTV0,Q93050,Q8NHS3,Q9NS69,O75964,O15118,Q8IXU6,Q13423,O43772,P98194,Q9HD20,P08183,Q9UDW1,Q6P4A7,Q9BSK2,Q9P0J0,P41440,Q03518,O15173,O43681,Q96NB2,P0CG08,Q7KZN9,P51790,Q9BQT8,Q9UBX3,P53985,Q96H78,P13073,P20674,O96000,Q9Y6M7,P38435,P30825,O95202,Q9HC07,O95182,P16615,Q9H2V7,P00403,Q9UJS0,Q86VD7,Q9UGP8,Q15388,Q8TB61,Q9Y619,O95168,O75746,Q9Y277,Q9H2D1,P06576,Q14728,O00400,P04114,P33527,O75027,Q15758,P16260,P61916,O95563,P20020,Q9Y5K8,Q8TDW0,O75380 82 +Ion transmembrane transporter activity 0.600962862769587 3.4135624679269316 0.0006411945726332 0.5825485828299115 0.1589311563006172 114 P00846,Q14728,O43681,P16615,Q4KMQ2,Q96NB2,P00403,P35670,P21796,P0CG08,P45880,Q70HW3,O00400,Q9Y487,P33527,Q9C0H2,O43808,Q7KZN9,Q9UJS0,Q86VD7,P51790,Q93050,Q15758,Q9BQT8,O75964,Q8TB61,Q9UBX3,P53985,Q13423,P13073,O43772,Q9Y619,P98194,Q9HD20,O95563,P20020,O75746,P20674,Q9Y5K8,Q9UDW1,Q9Y277,Q9Y6M7,P30825,Q6P4A7,O95202,Q9HC07,Q9H2D1,P06576,Q8TDW0,P41440 50 +Molecular transducer activity 0.6772780014493066 3.3726333480308397 0.0007445302453292 0.6373901721278934 0.1589311563006172 32 Q99720,O15173,Q14108,Q8WTV0,Q9UBG0,Q9UGP8,Q15758,Q4VCS5,Q08722,O75787,Q5KU26,O15118,Q15629,Q8WU17 14 +Proton transmembrane transporter activity 0.6659398551074013 3.2692132926179474 0.0010784697155352 0.7699982569269535 0.1589311563006172 38 P00846,P51790,Q93050,O95202,P06576,P00403,O75964,Q9Y487,Q13423,Q9UDW1,P20674,Q7KZN9,P13073 13 +Alcohol binding 0.8582459587293602 3.227652672895303 0.0012481041790781 0.817495347427093 0.1589311563006172 14 P21796,P45880,Q14108,Q9BZF3 4 +Cholesterol binding 0.8896062240660166 3.1196267812699574 0.0018108031578683 0.915292370519607 0.1589311563006172 12 P21796,P45880,Q14108,Q9BZF3 4 +Steroid binding 0.7626507531541075 3.109864955517698 0.0018717289750063 0.9220496847880784 0.1589311563006172 19 O15173,Q14108,P21796,P45880,Q9BZF3,O15118 6 +Sterol binding 0.8316090245177039 3.0941796948993754 0.0019735791151604 0.932164576831777 0.1589311563006172 14 P21796,P45880,Q14108,Q9BZF3 4 +Tetrapyrrole binding 0.7550271246473655 3.0279298438072284 0.0024623524519502 0.9651903229769156 0.1589311563006172 18 Q9H7Z7,O15173,P30519,Q8WUJ1,P09601,Q9NRV9,Q16850,O43169,Q7KZN9 9 +Protein transporter activity 0.7556330245119736 2.964235538916327 0.003034359338192 0.9840624979556848 0.1589311563006172 16 Q99595,O60830,Q9UGP8,Q9HD20,Q9NS69,Q9Y584 6 +Cation transmembrane transporter activity 0.608220732251848 2.9131615695582913 0.0035778942756055 0.9924168800214148 0.1589311563006172 79 P00846,P16615,Q4KMQ2,Q96NB2,P00403,P35670,Q70HW3,O00400,Q9Y487,O43808,Q7KZN9,Q86VD7,P51790,Q93050,Q15758,O75964,Q13423,P13073,O43772,Q9Y619,P98194,Q9HD20,P20020,P20674,Q9Y5K8,Q9UDW1,Q9Y6M7,P30825,O95202,Q9HC07,P06576 31 +Gated channel activity 0.7915895756030059 2.8893974998396623 0.0038598081869467 0.9948421247234356 0.1589311563006172 14 P21796,P45880,Q9C0H2,P0CG08 4 +Passive transmembrane transporter activity 0.6144848853438903 2.8862012611800982 0.0038992272336746 0.9951127641035784 0.1589311563006172 37 P00846,P0CG08,P21796,O75964,P45880,Q9C0H2 6 +Organic anion transmembrane transporter activity 0.6127071680670455 2.881604441938753 0.0039565608506224 0.9954812718632368 0.1589311563006172 35 Q86VD7,Q9Y619,Q9Y6M7,P30825,Q96NB2,Q15758,Q9H2D1,Q9BQT8,O00400,Q8TB61,Q9UBX3,P53985,O75746,P33527,P41440,Q14728,Q9UJS0 17 +Anion transmembrane transporter activity 0.6076794555327828 2.799066280155896 0.0051250616266498 0.9990865506300464 0.1589311563006172 53 O43681,Q4KMQ2,Q96NB2,P0CG08,P21796,P45880,O00400,P33527,Q9C0H2,O43808,Q9UJS0,Q86VD7,P51790,Q15758,Q9BQT8,Q8TB61,Q9UBX3,P53985,Q9Y619,O95563,O75746,Q9Y277,Q9Y6M7,P30825,Q9H2D1,Q8TDW0,P41440,Q14728 28 +Snap receptor activity 0.7466759049103144 2.777328157875988 0.0054807812823316 0.9994387564967344 0.1589311563006172 15 O43752,O95249,O15400,Q13277,Q9P2W9,O75396,O60499,Q9UNK0,Q12981,O14653 10 +Inorganic molecular entity transmembrane transporter activity 0.5751386361310632 2.6710570079179985 0.0075612803961013 0.9999676079025388 0.1589311563006172 85 P00846,O43681,P16615,P0CG08,P21796,P45880,Q9Y487,Q9C0H2,Q7KZN9,P51790,Q93050,O75964,Q9UBX3,Q13423,P13073,P98194,Q9HD20,P20674,Q9UDW1,Q9Y6M7,O95202,Q9HC07 22 +Hydrolase activity acting on glycosyl bonds 0.6357194709205034 2.649441913862639 0.0080624830377198 0.9999837205788928 0.1589311563006172 26 Q9NUJ1,P16278,O75503,P06280,O60476,Q9BTY2,P54802,O60502 8 +Organic acid transmembrane transporter activity 0.655477703515675 2.6294388865953797 0.0085525902700656 0.9999916956142008 0.1589311563006172 23 Q96H78,Q9Y619,P30825,Q96NB2,Q15758,Q9H2D1,Q9BQT8,P08183,Q9UBX3,P53985,O75746,P33527,P41440,Q9UJS0 14 +Anion channel activity 0.7548429993673109 2.583211415627623 0.0097885319530592 0.9999984813058924 0.1604934836137701 13 P21796,P45880,Q9C0H2,P0CG08 4 +Macromolecule transmembrane transporter activity 0.7534906082772848 2.5761909372353182 0.0099895466093342 0.9999988481902732 0.1604934836137701 13 Q99595,O60830,Q9UGP8,Q9NS69,Q9Y584 5 +Hydrolase activity hydrolyzing o glycosyl compounds 0.6720857795902785 2.5750588501582654 0.0100223032375768 0.999998898944867 0.1604934836137701 19 Q9NUJ1,P16278,P06280,O60476,Q9BTY2,P54802,O60502 7 +Monooxygenase activity 0.8779935275080754 2.5733186917900137 0.010072840798843 0.9999989729011702 0.1604934836137701 8 P30519,Q9BU89,P09601,Q15800,Q6UW02,Q16850,Q14534 7 +Phosphatidylcholine binding 0.9187288045829528 2.5712248828783992 0.0101339497729693 0.9999990557286976 0.1604934836137701 7 P21796,Q14108 2 +Protein transmembrane transporter activity 0.7729975133224571 2.557507279502664 0.0105425351406451 0.9999994618663328 0.163169691608622 12 Q99595,O60830,Q9UGP8,Q9NS69,Q9Y584 5 +Sphingolipid binding 0.8623131555035198 2.506496712805084 0.0121934191475234 0.9999999446460748 0.1824993063618349 8 P21796,P45880,P07602 3 +Active transmembrane transporter activity 0.5535986846377928 2.4794832940565703 0.0131572893421709 0.9999999853549478 0.1866690425420507 86 Q03518,O95182,P16615,O75306,O14678,P00403,P35670,O00400,P03886,P33527,O75027,Q7KZN9,O43676,P51790,Q15758,Q15388,Q9UBX3,P53985,P16260,P13073,P98194,O95168,Q9HD20,P08183,P20020,P20674,Q9Y5K8,Q9UDW1,O96000,Q9Y6M7,O95202,P06576,Q9P0J0,O75380,P41440 35 +Voltage gated channel activity 0.7770409925152095 2.452145453148894 0.0142007246265334 0.9999999965331934 0.1920902707381114 11 P21796,P45880,P51790,P0CG08 4 +Oxidoreduction driven active transmembrane transporter activity 0.5548294099056107 2.4414123001380283 0.0146299412710775 0.999999998084286 0.1920902707381114 33 O43676,O96000,O95182,P00403,P03886,P20674,Q9UDW1,Q9P0J0,Q7KZN9,P13073 10 +Active ion transmembrane transporter activity 0.5606771507420802 2.420154864113807 0.0155138985177623 0.999999999435764 0.1920902707381114 48 P16615,P00403,P35670,O00400,P33527,Q7KZN9,Q9BXP2,P51790,P13073,P98194,Q9HD20,P20020,P20674,Q9Y5K8,Q9UDW1,Q9Y6M7,O95202,P06576,P41440 19 +Quaternary ammonium group binding 0.7662149652476524 2.3995553207921394 0.0164149992441859 0.999999999837892 0.1961160436015905 11 P21796,Q14108 2 +Metalloendopeptidase activity 0.6964747049427396 2.380880599956839 0.0172713090593472 0.9999999999504992 0.1980268894154691 14 O75844,P22695,P42892,Q96TA2 4 +Exogenous protein binding 0.6444330803287781 2.3740808621562297 0.0175926972241349 0.9999999999682944 0.1980268894154691 18 Q14108,Q8WTV0 2 +Ceramide binding 0.889548184002087 2.3596517190924833 0.0182920993155055 0.9999999999879808 0.2012993001147 6 P21796,P45880,P07602 3 +Amino acid transmembrane transporter activity 0.7709779386362262 2.313283025982238 0.0207070833107876 0.9999999999995802 0.2068208586079859 10 Q9Y619,P30825,Q96NB2,O75746,Q96H78,Q9UJS0 6 +Secondary active transmembrane transporter activity 0.5940267093684919 2.3099613828289645 0.02089029218689 0.9999999999996748 0.2068208586079859 25 Q9Y6M7,P51790,O95202,Q15758,O00400,Q9UBX3,P53985,P16260,P41440 9 +Atpase coupled transmembrane transporter activity 0.5636679550809047 2.3087867545154817 0.0209554173919985 0.9999999999997028 0.2068208586079859 29 Q03518,Q04656,Q9NUT2,P16615,P98194,O14678,P06576,Q9Y5K8,Q9HD20,P35670,P08183,Q15388,P20020,P33527,O75027,P23634 16 +Inorganic anion transmembrane transporter activity 0.6005015296438766 2.265743847384764 0.0234670712186839 0.999999999999991 0.2161101577686712 23 Q9Y6M7,O43681,P51790,Q4KMQ2,Q8TDW0,P0CG08,P21796,P45880,Q9UBX3,P33527,Q9Y277,Q9C0H2 12 +Vitamin transmembrane transporter activity 0.7818081948485149 2.254122187334926 0.0241884822223448 0.9999999999999968 0.2161101577686712 9 P33527,Q9H2D1,P38435,P41440 4 +Sulfur compound transmembrane transporter activity 0.8042448398724968 2.2540858310300127 0.0241907688631528 0.9999999999999968 0.2161101577686712 8 Q70HW3,O00400,Q8TB61,Q9UBX3 4 +Primary active transmembrane transporter activity 0.5423350551094848 2.2527218601367656 0.0242766917317229 0.9999999999999972 0.2161101577686712 62 Q03518,O95182,P16615,O75306,O14678,P00403,P03886,P33527,O75027,Q7KZN9,O43676,Q15388,P13073,P98194,O95168,Q9HD20,P08183,P20020,P20674,Q9Y5K8,Q9UDW1,O96000,P06576,Q9P0J0,O75380 25 +Exopeptidase activity 0.545769920676102 2.235241997899678 0.0254014656587746 0.9999999999999994 0.221774334790071 30 O75844,Q9UIQ6,Q9H3G5,P42785,Q9NZ08,P55786,Q9HB40,O14773,Q7Z2K6 9 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.6687942011041754 2.226827100086703 0.0259588314640899 0.9999999999999998 0.2237716990765222 14 Q9H7Z7,Q15392,Q8N4Q0 3 +Palmitoyl protein hydrolase activity 0.8924426625084776 2.199421100508843 0.0278479936378039 1.0 0.2341294279919076 5 Q9UMR5,P50897 2 +Modified amino acid binding 0.6007095468820017 2.192185171820005 0.0283661387122127 1.0 0.235922531203067 21 Q9H7Z7,Q14108,Q8WTV0 3 +Voltage gated anion channel activity 0.827107115794342 2.191609634606814 0.0284077056661549 1.0 0.235922531203067 7 P21796,P45880,P51790,P0CG08 4 +Acid phosphatase activity 0.9590640011077994 2.175677227610478 0.0295794041555805 1.0 0.2418065342978574 4 Q9NPH0,Q9UNW1 2 +Oxidoreductase activity acting on a heme group of donors 0.8227395277097508 2.1730711605471784 0.0297749618847866 1.0 0.2418065342978574 7 P20674,Q7KZN9,P00403,P13073 4 +Metallopeptidase activity 0.5249078208057639 2.17238869957226 0.0298263566534802 1.0 0.2418065342978574 37 O00303,O75844,Q9UIQ6,P22695,Q9NZ08,P51665,P55786,O43847,P09960,Q96TA2,Q10713,P42892,Q7Z2K6,O75976 14 +Thiolester hydrolase activity 0.6164924497485296 2.1521227175773334 0.0313876903395868 1.0 0.2518375725259378 16 Q9UMR5,P50897,Q9NUJ1 3 +Cargo receptor activity 0.8161560724112471 2.145050956213789 0.0319487730592793 1.0 0.2543095875797418 7 Q5JRA6,Q14108,Q8WTV0,Q08380,Q5KU26 5 +Amide transmembrane transporter activity 0.8156681563843579 2.1429706581178767 0.0321154545254886 1.0 0.2543095875797418 7 Q03518,Q9H2D1,O00400,P41440 4 +O acyltransferase activity 0.6105376484859619 2.1155687014924154 0.0343815061275205 1.0 0.2627276281347558 16 Q9HCL2,P23786,Q8NCC3,P50416,Q99943 5 +Proton transporting atp synthase activity rotational mechanism 0.6862206276085563 2.112371230049632 0.0346546206543147 1.0 0.2627276281347558 12 P00846 1 +Proton channel activity 0.6862206276085563 2.112371230049632 0.0346546206543147 1.0 0.2627276281347558 12 P00846 1 +Dicarboxylic acid transmembrane transporter activity 0.7694963585998837 2.0992626865431285 0.0357937507528609 1.0 0.2663993908491618 8 Q9BQT8,O75746,Q9UBX3,P41440,Q9UJS0 5 +Proline rich region binding 0.8242118791246866 2.0905996246019516 0.0365639694390873 1.0 0.2691898723029025 6 Q9UQB8 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.5377901220252022 2.0544649349045225 0.0399307138411779 1.0 0.2837673644576107 28 P61457,P16435,P30519,Q9BU89,P09601,Q15800,Q6UW02,Q16850,Q14534,Q9H6W3 10 +Lysophospholipase activity 0.7847530660798914 2.0101361850029296 0.0444167772210957 1.0 0.2965473067408449 7 Q8NCC3 1 +Nucleobase containing compound transmembrane transporter activity 0.588678319644644 2.0008585944947423 0.04540763077157 1.0 0.3002193840333904 17 Q86VD7,Q9H2D1,L0R6Q1,O00400,Q8TB61,Q9BSK2,O43808,P41440 8 +Serine type carboxypeptidase activity 0.8406078241189889 1.9906874736096856 0.0465152567015689 1.0 0.306056906413222 5 P42785,Q9HB40,Q9H3G5,O75976 4 +Metal ion transmembrane transporter activity 0.5336906588447359 1.9712934573060596 0.0486903192984922 1.0 0.3178828451464606 27 Q04656,Q9Y6M7,P16615,Q9BXP2,P05023,P98194,O95202,Q9HC07,Q9HD20,P35670,Q6P4Q7,P20020,Q8TAD4,P23634 14 +Scavenger receptor activity 0.9025787184199178 1.960292942873644 0.0499615604083816 1.0 0.3182149177359685 4 Q14108,Q8WTV0 2 +Peptide binding 0.5091053572849717 1.9599765949307797 0.0499985259878834 1.0 0.3182149177359685 67 Q03518,Q9H7Z7,Q9UIQ6,P24390,Q9NQX7,Q8WTV0,Q9NZ08,Q15392,P55786,Q9Y584,O43731,P42892 12 +Atpase binding 0.5481093570561992 1.9427887370109829 0.0520416893096145 1.0 0.327396305796591 24 Q9Y487,Q93050,Q16740 3 +Abc type transporter activity 0.6737578460178922 1.9364636555479624 0.0528109397249187 1.0 0.327396305796591 11 Q03518,O14678,Q9HD20,P08183,P33527,O75027 6 +Atp dependent peptidase activity 0.8269762448905909 1.9350384952727684 0.0529855719736631 1.0 0.327396305796591 5 Q16740 1 +Serine type exopeptidase activity 0.7651225801736348 1.924752088190925 0.0542603805909296 1.0 0.327396305796591 7 P42785,Q9HB40,Q9H3G5,O14773 4 +Nucleotide transmembrane transporter activity 0.6158708921719478 1.9244778562619171 0.0542947137445348 1.0 0.327396305796591 14 Q86VD7,Q9H2D1,O00400,Q8TB61,Q9BSK2,P41440 6 +Symporter activity 0.6882792242136204 1.9130798751816185 0.0557378276846562 1.0 0.3286073086380137 10 Q9Y6M7,Q9BXP2,Q15758,O00400,P53985 5 +Mannosyltransferase activity 0.7611917381331187 1.907559243999097 0.0564482070034608 1.0 0.3286073086380137 7 Q6ZXV5,O60762,Q9BV10,Q9BT22 4 +L amino acid transmembrane transporter activity 0.7266372164797191 1.9044120653388372 0.0568565390745345 1.0 0.3286073086380137 8 Q9Y619,P30825,Q15758,O75746,Q9UJS0 5 +Serine hydrolase activity 0.5570339190900186 1.9000340582781947 0.0574286502532672 1.0 0.3288653216113119 21 Q9H3G5,P42785,Q6PIU2,P67812,Q9HB40,O14773,Q16740 7 +P type transmembrane transporter activity 0.7256214030409852 1.8997424919274295 0.0574669211038856 1.0 0.3288653216113119 8 Q04656,P16615,P98194,P35670,P20020,P23634 6 +Transition metal ion transmembrane transporter activity 0.7739327296248355 1.8778805751271752 0.0603975042732105 1.0 0.3382081510615007 6 P98194,Q9HC07,Q9HD20,P35670,Q8TAD4 5 +Antiporter activity 0.6179718908761535 1.841302484785159 0.0655772438155892 1.0 0.349929983118865 13 O95202,P41440,P51790,Q9UBX3 4 +Organic cation transmembrane transporter activity 0.745807842804587 1.839971312787788 0.0657724491031053 1.0 0.349929983118865 7 O43772,Q70HW3 2 +Protein lipid complex binding 0.8665268640124777 1.8205439356385589 0.0686762118032668 1.0 0.361146719984747 4 Q8WTV0 1 +Iron ion binding 0.5340818025391183 1.8059276987055464 0.0709296338648406 1.0 0.3657968379431275 23 Q9BV57,Q9BU89,P22830,Q15800,Q6UW02,Q9UMS0,Q16850,Q9H6W3 8 +Proteasome binding 0.6861270200765097 1.804378921459161 0.0711719251504616 1.0 0.3657968379431275 9 O95456,P46379 2 +Wide pore channel activity 0.8580004960648473 1.7872516714487563 0.0738968212940629 1.0 0.3755502634422153 4 P21796 1 +Porin activity 0.8580004960648473 1.7872516714487563 0.0738968212940629 1.0 0.3755502634422153 4 P21796 1 +C4 dicarboxylate transmembrane transporter activity 0.7506468305303988 1.7777581087828664 0.0754435913734545 1.0 0.3800630597832372 6 Q9H936,Q15758,O75746,Q9UBX3,Q9UJS0 5 +Xenobiotic transmembrane transporter activity 0.8540589918837851 1.7718319405650729 0.0764224588014639 1.0 0.381272486767743 4 P08183,P41440 2 +Organophosphate ester transmembrane transporter activity 0.5721469877050179 1.7658606639802172 0.077419227959298 1.0 0.38483572438162 15 Q86VD7,Q9H2D1,O00400,Q8TB61,Q9BSK2,P41440 6 +Er retention sequence binding 0.9819121447028416 1.7565535148296365 0.0789939422582324 1.0 0.3870134868910523 2 P24390 1 +Oxidoreductase activity acting on the ch ch group of donors 0.46931219681646 1.7423122966406512 0.0814538128976438 1.0 0.3952754046564455 32 Q9H7Z7,O15254,Q15392,Q8N4Q0,Q7KZN9 5 +Palmitoyl coa hydrolase activity 0.7228560949410284 1.738262446008737 0.0821645803070791 1.0 0.3968374410575952 7 P50897 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.9757751937984468 1.732204000597203 0.0832372470036126 1.0 0.4005976339891182 2 P30519 1 +Pattern recognition receptor activity 0.9735142118863032 1.7232278254014706 0.0848473337223065 1.0 0.4049636910511613 2 Q8WTV0 1 +Peptide antigen binding 0.7364682245708871 1.716322221688012 0.086103083323012 1.0 0.4071958315484113 6 Q03518,Q15392,P10321 3 +Cation channel activity 0.5248383343764621 1.7079620550173311 0.0876433834492795 1.0 0.4116216836479958 22 P00846 1 +Signal sequence binding 0.5088290135326123 1.696767292261152 0.0897406647248422 1.0 0.4143280859499494 25 P24390,Q9Y584 2 +Galactoside binding 0.9647932816537452 1.6885807486059574 0.0912998025224804 1.0 0.4191048223874433 2 P16278 1 +Threonine type endopeptidase activity 0.6800940016086875 1.688106957380287 0.0913906991549711 1.0 0.4191048223874433 8 P28074,P28072,P49721,P28070,P20618 5 +Mhc protein binding 0.6591879079613727 1.6737307854116432 0.094183520592197 1.0 0.4254528096810817 9 Q03518,P07437,Q9NUQ9,P51572 4 +Membrane insertase activity 0.676713006216522 1.6722129521665918 0.0944823373344503 1.0 0.4254528096810817 8 P62072,Q9P0I2,Q15070 3 +Modified amino acid transmembrane transporter activity 0.8274157399500659 1.6671337494186615 0.0954878125990581 1.0 0.4264078713439908 4 Q9H2D1,P41440 2 +Phospholipase binding 0.8229716561583049 1.64959548335746 0.0990256994101337 1.0 0.4364822090504924 4 P07196 1 +Pdz domain binding 0.6168350872751753 1.639132447655713 0.1011856786938332 1.0 0.4422356979650924 11 Q9Y4G8,P51790,P63218,P20020,Q9UQB8 5 +Mannose binding 0.7182770370218555 1.6370032541679291 0.1016297896204654 1.0 0.4422356979650924 6 P35613,O60762,O75503 3 +Sterol transporter activity 0.697259750536774 1.623660105286565 0.1044483699089071 1.0 0.4466238023289989 7 O15118,Q9BZF3,P04114 3 +G protein beta gamma subunit complex binding 0.7514718196413965 1.6215533419335832 0.1048990198040837 1.0 0.4466238023289989 5 Q14344,P04899,P41208 3 +P type calcium transporter activity 0.8154492566257279 1.6198637097767807 0.1052615569365702 1.0 0.4466238023289989 4 P98194,P20020,P16615 3 +Palmitoyltransferase activity 0.7132999056506313 1.6152085649867185 0.106265536377053 1.0 0.4494834178433113 6 P23786,P50416,O15269 3 +Lamin binding 0.6950092848017809 1.61352786118142 0.1066298752444985 1.0 0.4496281426718482 7 P42167,O94901,Q5SNT2 3 +Glycolipid binding 0.6073844342363146 1.588932418608979 0.1120756511753067 1.0 0.462566778487175 11 P50897,P07602,Q9UM22,Q9NZJ7,O14773 5 +Nadh dehydrogenase activity 0.4930753692850466 1.5792610806967853 0.1142761848943092 1.0 0.4702240598974295 25 O43676,O96000,O95182,O95831,P03886,Q9P0J0 6 +Threonine type peptidase activity 0.638052615838508 1.5700983148459624 0.1163922405794601 1.0 0.4737160274716598 9 P28074,P28072,P49721,P28070,P20618 5 +Glycosphingolipid binding 0.7966319940852011 1.5452588746119889 0.1222836586903599 1.0 0.4739358547674616 4 Q9UM22,P07602 2 +Metalloexopeptidase activity 0.5144510586034509 1.537825281551699 0.1240913403207526 1.0 0.4739358547674616 18 O75844,O75976,Q9UIQ6,Q9NZ08,P55786,P09960,Q7Z2K6 7 +Solute proton antiporter activity 0.9250645994832014 1.530385791479867 0.125921263848308 1.0 0.4739358547674616 2 P51790 1 +Oxidoreductase activity acting on nad p h 0.4478137217621982 1.530110611304074 0.1259893521175497 1.0 0.4739358547674616 35 O43676,O96000,O95182,O95168,O95831,P03886,Q13423,Q9P0J0,Q7KZN9 9 +Acidic amino acid transmembrane transporter activity 0.7921784098254693 1.5275575091376226 0.126622438357784 1.0 0.4739358547674616 4 Q15758,O75746,Q9UJS0 3 +L aspartate transmembrane transporter activity 0.7921784098254693 1.5275575091376226 0.126622438357784 1.0 0.4739358547674616 4 Q15758,O75746,Q9UJS0 3 +Inositol phosphate phosphatase activity 0.9202196382428884 1.5110717473892017 0.1307701720086993 1.0 0.4839917779235013 2 Q9UNW1 1 +Lysophosphatidic acid binding 0.9189276485788034 1.5059211704511395 0.132087411179778 1.0 0.4875421518343028 2 P50897 1 +G protein alpha subunit binding 0.7844570810864153 1.4968319933812002 0.1344369792625168 1.0 0.4927909914745552 4 P80303,Q02818 2 +Oxidoreductase activity 0.3598383164641854 1.4920786384244078 0.1356785311736401 1.0 0.4927909914745552 238 Q9H7Z7,O95182,P30519,O15254,P00403,O95831,Q6UW02,P03886,Q3SXM5,O43169,P78417,Q7KZN9,O43676,Q53GQ0,Q9BU89,P14406,Q9H3N1,Q15392,Q99536,Q16850,Q8N0U8,Q13423,P13073,Q6YN16,Q8NBM8,O95168,P09601,Q15800,Q8N4Q0,P51648,P20674,O76062,Q9UDW1,Q14534,O96000,P16435,O43819,Q9HBH5,Q9UHG3,Q8IXB1,Q9P0J0,Q8NBX0,Q9H6W3,P30837,Q06136 45 +Low density lipoprotein particle binding 0.9351338782749844 1.4737942425734327 0.1405369989576073 1.0 0.5030754601548496 3 Q8WTV0 1 +Calcium ion transmembrane transporter activity 0.5250512041088056 1.4731642375637404 0.1407067556010859 1.0 0.5030754601548496 15 P16615,P98194,O95202,Q9HC07,P20020 5 +Protein kinase a regulatory subunit binding 0.663804956792353 1.4721766056883778 0.1409731930870965 1.0 0.5030754601548496 7 Q9H3P7,Q92667 2 +Atpase coupled cation transmembrane transporter activity 0.5031897222997571 1.462110385315489 0.1437109632939317 1.0 0.5079502759043764 18 Q04656,P16615,P98194,P06576,Q9HD20,P35670,P20020,Q9Y5K8,P23634 9 +Syntaxin binding 0.5362810008859058 1.451371184404038 0.1466765291682081 1.0 0.5148799812554111 14 O43752,O60499,Q9UNK0,O15400 4 +Protein carrier chaperone 0.5804964676963411 1.4449500548290426 0.1484719150784617 1.0 0.51755764839915 11 P62072,Q9NPA0,Q9P0I2,Q15070 4 +Manganese ion transmembrane transporter activity 0.9247172859450774 1.4358313453088962 0.151050338101079 1.0 0.522285990903092 3 P98194,Q9HD20 2 +Guanyl nucleotide exchange factor activity 0.4638442814787972 1.433594208712721 0.1516880971295313 1.0 0.5226481953851001 27 Q9Y4G8,Q02818,P80303,Q5VZ89,Q14344,Q9Y4F1,A4D1U4,Q9NPQ8,Q9NR50 9 +Phosphatidyl phospholipase b activity 0.9237043851337348 1.4321391166050776 0.1521040116608556 1.0 0.5226481953851001 3 Q8NCC3 1 +Acetylglucosaminyltransferase activity 0.669919074377727 1.423737563600152 0.1545224555731086 1.0 0.5274676303021903 6 P06865,O15294 2 +Solute cation symporter activity 0.6239943524198776 1.421556760746787 0.1551549647602259 1.0 0.5283026550085693 8 O00400,Q9Y6M7,Q9BXP2 3 +L ornithine transmembrane transporter activity 0.8959948320413452 1.4145194577391331 0.1572094384329543 1.0 0.5313132882026892 2 P30825 1 +Phosphatidylserine binding 0.5883051291812158 1.4057195477609217 0.1598074199977233 1.0 0.5347855185181797 10 Q14108 1 +Oxidoreductase activity acting on a sulfur group of donors 0.4634190171735463 1.390791519553299 0.1642886554575184 1.0 0.542642799130433 26 Q8NBM8,Q9H3N1,Q6ZRP7,O43819,Q8IXB1,Q9UHG3,P78417 7 +Carnitine o acyltransferase activity 0.8879198966408282 1.3823627897839132 0.1668603353918549 1.0 0.542642799130433 2 P23786 1 +O palmitoyltransferase activity 0.8879198966408282 1.3823627897839132 0.1668603353918549 1.0 0.542642799130433 2 P23786 1 +Single stranded dna exodeoxyribonuclease activity 0.6949966124166569 1.3822745627926123 0.1668874133251399 1.0 0.542642799130433 5 Q9UQ84 1 +Folic acid transmembrane transporter activity 0.8833979328165287 1.36436592175171 0.1724524277633929 1.0 0.5494855906035965 2 P41440 1 +Carboxypeptidase activity 0.5492966029460934 1.3629609469760162 0.172894818877922 1.0 0.5494855906035965 12 P42785,Q9HB40,Q9H3G5 3 +Mhc class i protein binding 0.6117583787578558 1.3627134425347522 0.1729728396083572 1.0 0.5494855906035965 8 Q03518,P07437,P51572 3 +Phosphate ion binding 0.6888402832519148 1.3560192007272445 0.1750930589735395 1.0 0.5494855906035965 5 Q8NCH0 1 +Amide binding 0.431669196516603 1.349277065777622 0.1772479892428597 1.0 0.5495970710106135 98 Q9H7Z7,Q03518,Q9H3P7,Q9UIQ6,P24390,Q9NQX7,Q8WTV0,Q15392,P07602,P21796,P55786,P45880,Q9UM22,Q9Y584,O43731,P42892,P41440 17 +Organic hydroxy compound transmembrane transporter activity 0.8769379844961165 1.3386730529464563 0.1806771324742944 1.0 0.5554904163205169 2 P53985 1 +Solute cation antiporter activity 0.8912282955668385 1.3137654622457202 0.188925143695442 1.0 0.5646943035082893 3 P51790 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.8891760904685021 1.306290335554285 0.1914538424258958 1.0 0.5646943035082893 3 Q15800,Q16850 2 +Abc type xenobiotic transporter activity 0.8682170542635537 1.3040262306253056 0.1922246390144004 1.0 0.5646943035082893 2 P08183 1 +Efflux transmembrane transporter activity 0.8682170542635537 1.3040262306253056 0.1922246390144004 1.0 0.5646943035082893 2 P08183 1 +Heme transmembrane transporter activity 0.8669250645994726 1.2988977239990156 0.1939790308760953 1.0 0.5669515880970856 2 O15173 1 +Neutral amino acid transmembrane transporter activity 0.7335714404849121 1.293518229950577 0.1958318831739742 1.0 0.5699209933396431 4 Q96NB2 1 +Volume sensitive anion channel activity 0.7327324968244588 1.2901593248843175 0.1969953454682562 1.0 0.570277032062562 4 Q9C0H2 1 +Chloride channel inhibitor activity 0.8643410852713154 1.28864444429183 0.1975217247383507 1.0 0.570277032062562 2 Q9UNK0 1 +Chloride channel regulator activity 0.8643410852713154 1.28864444429183 0.1975217247383507 1.0 0.570277032062562 2 Q9UNK0 1 +Tap binding 0.7274544629363158 1.2690265600371422 0.2044315913082721 1.0 0.5777560622018663 4 Q03518,P10321 2 +Mhc class ib protein binding 0.8735666176387225 1.2494799646321264 0.2114895770509379 1.0 0.590263942506921 3 Q03518 1 +Electron transfer activity 0.4298540798048337 1.243267607357397 0.2137692366824375 1.0 0.5932790906601891 54 O43676,O96000,O95182,P14406,O95168,P00403,P03886,P20674,Q9UDW1,Q9P0J0,Q7KZN9,P13073 12 +Lipase activity 0.4679246508972068 1.2381818243058005 0.2156486493713614 1.0 0.5945616608173973 19 Q9H6V9,P09601,Q8NCC3,Q8NHP8,Q8IY17 5 +Endopeptidase activity 0.4289073481104982 1.2259722311871089 0.2202091250232623 1.0 0.5971210684532863 56 P20618,Q96K76,P67812,Q16740,Q99436,Q92643,P28070,P22695,P28072,Q4J6C6,Q9NZ08,P49721,O43847,P42892,Q9BXS4,O75844,P28074,Q96TA2,Q10713,O14773 20 +Purine nucleotide transmembrane transporter activity 0.5399575576471132 1.2251839174897317 0.2205059325753364 1.0 0.5971210684532863 11 Q86VD7,O00400,Q8TB61,P41440 4 +Ubiquitin conjugating enzyme binding 0.7078283889700347 1.190465345558386 0.2338635428023452 1.0 0.616096992837126 4 Q9BTE7 1 +Antigen binding 0.5752001276183949 1.185851024527188 0.235681137098171 1.0 0.6183166224418074 8 Q03518,Q15392,P10321 3 +Cytokine activity 0.6097640338291852 1.155066511890906 0.2480631904981969 1.0 0.6303396743629556 6 P43490 1 +Sulfuric ester hydrolase activity 0.8288113695090288 1.1483336908039752 0.2508308359430014 1.0 0.6317661006759295 2 O43681 1 +Peptidase activity 0.4073145439308077 1.1481035742463934 0.2509258088428991 1.0 0.6317661006759295 105 P02786,P42785,P20618,Q96K76,P67812,Q9HB40,Q16740,Q9UIQ6,Q99436,Q92643,Q9BT78,P51665,O43464,P28070,O75976,P22695,Q9H3G5,P28072,Q4J6C6,Q9NZ08,P49721,P55786,O43847,P09960,Q9NUQ7,P42892,Q7Z2K6,Q9BXS4,O75844,O00303,P28074,P10619,Q96TA2,Q10713,O14773,Q9HBH5 36 +Fad binding 0.5230594618321209 1.1329297435342387 0.2572437582120686 1.0 0.6331932693263067 11 O95831,Q15392,O15254 3 +Cyclin dependent protein kinase activity 0.6364828740978897 1.1321904264340503 0.2575543841459426 1.0 0.6331932693263067 5 P50750,P11802 2 +Collagen binding 0.5485501953271209 1.1227625610192389 0.2615383498836727 1.0 0.6335076552376153 9 Q9UBG0,Q53GQ0,O75718,Q32P28 4 +Sulfotransferase activity 0.8217054263565736 1.1204685030803434 0.2625141673601789 1.0 0.6335076552376153 2 Q8NCH0 1 +Cytoskeleton nuclear membrane anchor activity 0.81750645994832 1.1040418274000137 0.2695749938845972 1.0 0.6374325376229539 2 O94901 1 +Cyclic nucleotide binding 0.6296110118124428 1.102825989068633 0.2701027396001434 1.0 0.6375735378429728 5 P41440 1 +Nitric oxide synthase binding 0.8149224806201572 1.0939485304493837 0.2739775524452503 1.0 0.6438644779030356 2 P50570 1 +Oxidoreductase activity acting on nad p h heme protein as acceptor 0.6830078600705738 1.0913213261323946 0.2751315169894028 1.0 0.6438644779030356 4 Q7KZN9 1 +Glutamate receptor binding 0.6255683011996392 1.085562713853102 0.2776725035341685 1.0 0.646032604028892 5 O75955,P41440 2 +Ganglioside binding 0.8281098546042107 1.0849240600195555 0.2779552907202134 1.0 0.646032604028892 3 Q9UM22,P07602 2 +Coa hydrolase activity 0.5404503719088518 1.0818897218543069 0.2793015324436743 1.0 0.6480556851589171 9 P50897 1 +Hexosaminidase activity 0.6225707929176849 1.0727695988342756 0.2833745042175182 1.0 0.6508534144085325 5 P54802,O60502 2 +Dolichyl phosphate mannose protein mannosyltransferase activity 0.8091085271317857 1.07128415481313 0.2840416822058844 1.0 0.6512874935427855 2 O60762 1 +Gtpase activating protein binding 0.621814614943913 1.0695433233230522 0.2848249181822833 1.0 0.6518896514011157 5 P07437,Q13526,Q14C86 3 +Phosphatidylglycerol binding 0.8081395348837151 1.067513152609407 0.2857401775965242 1.0 0.6518896514011157 2 Q9UJZ1 1 +Cardiolipin binding 0.8081395348837151 1.067513152609407 0.2857401775965242 1.0 0.6518896514011157 2 Q9UJZ1 1 +Carbohydrate derivative transmembrane transporter activity 0.4734493458608425 1.066113568927775 0.2863723065327699 1.0 0.6522392667184491 14 Q86VD7,O00400,Q8TB61,O43808,P41440 5 +Sodium channel regulator activity 0.6731990209521238 1.052268309440995 0.2926764669348149 1.0 0.661398703375023 4 Q96PU5 1 +Phospholipid transporter activity 0.6143475840548072 1.0377102712526645 0.2994049616122682 1.0 0.6710604420640239 5 P08183 1 +Prenyltransferase activity 0.8148626817447493 1.037371064862186 0.2995629579845276 1.0 0.6710604420640239 3 P37268,Q9Y5Z9 2 +Glutathione disulfide oxidoreductase activity 0.8103966538513759 1.0213957474944968 0.3070669792794125 1.0 0.6801032674188956 3 P78417 1 +Mitochondrion targeting sequence binding 0.8103143675992416 1.0211016921402605 0.3072062614950293 1.0 0.6801032674188956 3 Q9Y584 1 +Chaperone binding 0.3969306518069994 1.0158043561745698 0.3097225612114125 1.0 0.6801032674188956 42 O43615,O95817,Q96KC8,Q14108,Q07812,O14976,P02786,Q9UL15,Q8IXB1,O43808,P62072 11 +Metalloaminopeptidase activity 0.512508353850671 1.0092653650629668 0.3128473858301253 1.0 0.6801032674188956 10 P55786,Q9UIQ6 2 +Protease binding 0.4097298522900327 1.0027798403609218 0.3159670977199296 1.0 0.6801032674188956 27 P41440,P46379,Q96RR1,O75955,P07602,P14174,Q13586,Q8WU17 8 +1 phosphatidylinositol binding 0.660147363667974 1.0004724580698587 0.3170819198318639 1.0 0.6801032674188956 4 Q8WTV0 1 +Ether hydrolase activity 0.6571556737618673 0.9886323043204148 0.3228430748544686 1.0 0.685258706058174 4 P07099 1 +Epoxide hydrolase activity 0.6571556737618673 0.9886323043204148 0.3228430748544686 1.0 0.685258706058174 4 P07099 1 +Adenyl nucleotide exchange factor activity 0.5577829411502524 0.9843380074599402 0.3249493477307097 1.0 0.6858090526545753 7 O95817,Q9UL15 2 +Atpase regulator activity 0.5577829411502524 0.9843380074599402 0.3249493477307097 1.0 0.6858090526545753 7 O95817,Q9UL15 2 +Sodium ion transmembrane transporter activity 0.5574145873730139 0.9826403530242828 0.3257844765547064 1.0 0.6858090526545753 7 Q9Y6M7,P05023,P55011,Q6P4Q7,Q9Y289 5 +Peptide transmembrane transporter activity 0.7990312960200809 0.9808870497688524 0.3266484443742876 1.0 0.6862974751776101 3 Q03518 1 +Ionotropic glutamate receptor binding 0.6545614906302184 0.9783763943050132 0.3278881988311863 1.0 0.6870518873970397 4 P41440 1 +Nucleotidase activity 0.5697836561459138 0.9761738276536388 0.328978330686458 1.0 0.6875118025298237 6 Q969T7 1 +Phosphatase regulator activity 0.4343820013055078 0.974878407038274 0.3296205781984376 1.0 0.6875118025298237 16 Q86XL3,Q9C0I1,P78318,Q8TF05 4 +Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor 0.5988641465695261 0.9718908819758848 0.3311048363720463 1.0 0.6875118025298237 5 Q15067,P50336,O15254 3 +Adp transmembrane transporter activity 0.5979011881688252 0.9678077739238528 0.3331403806111561 1.0 0.6875118025298237 5 Q86VD7 1 +Lipopolysaccharide binding 0.55334099868569 0.9638743279083192 0.3351089361143005 1.0 0.6875118025298237 7 Q8WTV0 1 +Hydrolase activity acting on ester bonds 0.2963239851631299 0.9565733754488968 0.3387826325745637 1.0 0.6898269764084796 162 O43681,Q9NUJ1,Q9H6V9,Q9NPH0,Q9UMR5,O00584,O14734,P50897,Q8NCC3,Q969T7,Q9NQ88,Q8TF05,O95453,Q6PIU2,P09601,Q99956,Q15165,Q9UQ84,Q9UNW1,P11117,Q8NHP8,Q10713,P49902,Q8IY17 24 +Cyclin binding 0.5022519222969474 0.9554657882727132 0.339342198380089 1.0 0.6898269764084796 10 P12956 1 +Scaffold protein binding 0.4303771561880449 0.9481643274826168 0.3430458043170312 1.0 0.6923612823789134 16 P12956,Q9UQB8,P07602 3 +Heparin binding 0.4991985647450254 0.9394662792354612 0.3474913974608098 1.0 0.6949327843914526 10 Q53GQ0,O14737,O94813 3 +Copper ion transmembrane transporter activity 0.7729328165374701 0.931985043672298 0.3513442548847139 1.0 0.6949327843914526 2 P35670 1 +Misfolded protein binding 0.4505779940914171 0.9250303455004012 0.3549501229162195 1.0 0.6949327843914526 14 P46379 1 +Atp transmembrane transporter activity 0.556678995834966 0.917827545367218 0.3587091588655398 1.0 0.697945534821236 6 Q6NUK1,Q86VD7,O43808,P12236 4 +Protein phosphatase 2a binding 0.5192671766596735 0.9143585738734324 0.3605284618830655 1.0 0.7004846862835025 8 Q86XL3,P78318 2 +Hormone binding 0.5541636250226654 0.906657366673059 0.364588015165955 1.0 0.7063568657980523 6 O43847,P42892 2 +Endopeptidase activator activity 0.6338046043899518 0.8967482430409236 0.36985327144385 1.0 0.707500218688938 4 Q9UL46 1 +Molecular carrier activity 0.3719173902600687 0.8853679413957408 0.3759582171166722 1.0 0.714846237865865 32 Q04656,O95817,Q9NPA0,O00410,Q9UI26,Q9P0I2,O43819,Q96P70,O75880,P52292,P62072,Q15070 12 +Folic acid binding 0.7707848392336483 0.8813053092777747 0.378152593213763 1.0 0.714846237865865 3 P41440 1 +Intramembrane lipid transporter activity 0.7702746365105207 0.8795233567014433 0.37911757469797 1.0 0.714846237865865 3 Q4KMQ2,P08183 2 +Amyloid beta binding 0.4761531468575935 0.8766723662211191 0.3806646204000188 1.0 0.714846237865865 11 O60925,Q9NQX7,Q8WTV0 3 +Protein phosphatase regulator activity 0.4531583905788158 0.876178970650437 0.3809327469031573 1.0 0.714846237865865 13 Q86XL3 1 +Lipid transporter activity 0.4159166353668584 0.8759791167848284 0.3810413867038311 1.0 0.714846237865865 19 P61916,O14678,P08183,Q9BZF3,O15118,P04114,P33527 7 +Serine transmembrane transporter activity 0.7649088747502322 0.8608233581532168 0.3893353381432161 1.0 0.723430737450287 3 Q96NB2 1 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.5366780474031873 0.8293463536325153 0.4069084483397964 1.0 0.7409215329395759 6 Q9UHG3,Q8NBM8 2 +Clathrin binding 0.4100681685072843 0.8183331035295461 0.413167008655483 1.0 0.7464434949465169 17 Q5VW38 1 +3 hydroxyacyl coa dehydratase activity 0.7416020671834604 0.8145352712022522 0.4153383747792696 1.0 0.7472798764192407 2 Q6Y1H2 1 +Structural constituent of synapse 0.5587710146151169 0.8034390705606532 0.4217210001862566 1.0 0.7545524972502614 5 P07196,Q16352 2 +Solute proton symporter activity 0.6093380183480097 0.801808588164077 0.4226636900076479 1.0 0.7545524972502614 4 O00400 1 +Leukotriene c4 synthase activity 0.7338501291989644 0.7860643934658912 0.4318297630998446 1.0 0.76625493716661 2 O14880 1 +Voltage gated chloride channel activity 0.7412657778280617 0.7794055286992406 0.4357408680760275 1.0 0.768736643131855 3 P51790 1 +Phosphatase activity 0.3708432622561714 0.7696268394698028 0.4415212793966141 1.0 0.7719537644906141 43 Q9UNW1,Q9NPH0,P11117,Q969T7,Q10713,P49902,Q8TF05,Q99956 8 +Class i dna apurinic or apyrimidinic site endonuclease activity 0.728682170542633 0.7672325669063446 0.4429432531853894 1.0 0.7734470651775646 2 P78549 1 +Acylglycerol o acyltransferase activity 0.4653583789508044 0.763206090948113 0.4453404968351058 1.0 0.7752456649686564 10 Q8NCC3,Q99943 2 +Lipid binding 0.3481938629259089 0.7614389396462568 0.4463949366030779 1.0 0.7752456649686564 128 A6NIH7,O15173,Q14108,O15254,P07602,P21796,P45880,Q9BZF3,P50897,Q8WTV0,Q9UJZ1,Q9Y5X1,Q9UM22,Q8NCC3,O15118,Q13277,Q13432,P38435,O14773 19 +L serine transmembrane transporter activity 0.7248062015503801 0.7531908094385582 0.4513352613239776 1.0 0.7800997790904283 2 Q15758 1 +Galactosidase activity 0.732901976341042 0.7510358065167291 0.4526311068898394 1.0 0.7813479944029929 3 P16278 1 +Hexosyltransferase activity 0.3632369659239833 0.7366610847248991 0.4613284777442508 1.0 0.7883681137862856 39 Q9BT22,Q9BV10,P06865,O15294,Q6ZXV5,Q13126,O60762,P46977,O43505,Q86SF2,P04843 11 +Glycosaminoglycan binding 0.4166880201470607 0.7175976681171747 0.4730053958711062 1.0 0.792701501634181 14 P04114,Q53GQ0,O14737,O94813 4 +Nadp retinol dehydrogenase activity 0.4992551640941747 0.7174372672993414 0.4731043314364114 1.0 0.792701501634181 7 Q9BTZ2,Q9HBH5,Q8NBN7 3 +Transferase activity transferring alkyl or aryl other than methyl groups 0.3933078685311325 0.7061381706346647 0.480102216193345 1.0 0.7955184998091944 17 P37268,Q9NR45,P49366,P78417,Q9Y5Z9,P14324 6 +Disulfide oxidoreductase activity 0.3859878749854645 0.7033783474417007 0.4818199966115482 1.0 0.7955184998091944 22 Q9H3N1,Q6ZRP7,O43819,Q8IXB1,P78417 5 +Intramolecular oxidoreductase activity transposing c c bonds 0.4960988223372056 0.7033030141357856 0.4818669327038072 1.0 0.7955184998091944 7 Q13011 1 +Hsp70 protein binding 0.4032523065102925 0.6973023925524098 0.4856135710831393 1.0 0.7997650348430905 15 P46379 1 +Transcription coactivator binding 0.5052337331496577 0.6924358983642444 0.488663628363867 1.0 0.8009143945025113 6 Q00059,Q71SY5,P50750 3 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.3617169774999025 0.6782375449565055 0.4976210908528584 1.0 0.8088062636082767 29 O43676,O96000,O95182,O75306,O95168,Q16718,Q7Z4W1,Q9BTZ2,P03886,Q9P0J0,O75380 11 +Atpase coupled inorganic anion transmembrane transporter activity 0.7018733850129045 0.671690740232744 0.5017805975315306 1.0 0.8107995804817617 2 P33527 1 +O methyltransferase activity 0.4652774058472968 0.6567463508262634 0.511344025606155 1.0 0.81099108646743 8 O60725 1 +Phosphoric ester hydrolase activity 0.3659078337127128 0.6499310225651609 0.5157367782203295 1.0 0.81099108646743 53 Q9UNW1,Q9NPH0,P09601,P11117,Q969T7,Q10713,P49902,Q8TF05,Q99956 9 +Snare binding 0.3654221918005422 0.6495816074159202 0.5159625168365669 1.0 0.81099108646743 27 O43752,O15400,Q13277,O60499,Q9UNK0,O14653 6 +Structural constituent of postsynapse 0.7014539579967758 0.6468156648210528 0.51775125280188 1.0 0.81099108646743 3 P07196,Q16352 2 +Steroid dehydrogenase activity 0.4522757455104148 0.6420042637894317 0.5208704145609584 1.0 0.81099108646743 9 Q53GQ0,Q3SXM5 2 +Growth factor binding 0.4208480203457988 0.6345067302737532 0.5257501759424064 1.0 0.8155714574414094 12 Q15375,Q92896 2 +Intramolecular oxidoreductase activity 0.3714982365989212 0.6302003339478469 0.5285635208216743 1.0 0.8169311792051899 24 Q9H7Z7,Q13011 2 +Potassium chloride symporter activity 0.6873385012919848 0.6216039295189206 0.5342023365230297 1.0 0.8169311792051899 2 Q9BXP2 1 +Cation chloride symporter activity 0.6873385012919848 0.6216039295189206 0.5342023365230297 1.0 0.8169311792051899 2 Q9BXP2 1 +Anion cation symporter activity 0.6873385012919848 0.6216039295189206 0.5342023365230297 1.0 0.8169311792051899 2 Q9BXP2 1 +Peroxisome targeting sequence binding 0.6831395348837221 0.6073864377137015 0.5435944868027196 1.0 0.8226396566947823 2 Q9NXR7 1 +Lrr domain binding 0.6851747416982361 0.5946443357265329 0.5520812375018713 1.0 0.8279186319716021 3 Q6P1K2 1 +Leucine zipper domain binding 0.6851747416982361 0.5946443357265329 0.5520812375018713 1.0 0.8279186319716021 3 Q6P1K2 1 +Acetyl coa hydrolase activity 0.6817954495019712 0.5839878399706943 0.559228493235798 1.0 0.8342488584744325 3 O14734 1 +Signaling receptor regulator activity 0.3841317052695054 0.5782561857938121 0.56309117044272 1.0 0.8364479313224764 15 Q9UMX5,P43490 2 +Trna methyltransferase activity 0.4670019886389485 0.5751054867923963 0.5652199573944183 1.0 0.8364479313224764 7 Q08J23 1 +Cytidylyltransferase activity 0.6787763307133365 0.5745204418696879 0.565615671621146 1.0 0.8364479313224764 3 Q9NR45 1 +Double stranded rna adenosine deaminase activity 0.6702196382428944 0.5644056933587079 0.5724780650797092 1.0 0.8393630961092851 2 Q9NZI8 1 +Adenosine deaminase activity 0.6702196382428944 0.5644056933587079 0.5724780650797092 1.0 0.8393630961092851 2 Q9NZI8 1 +Guanylate kinase activity 0.6686046511627839 0.5591179663763151 0.576081213933701 1.0 0.8393630961092851 2 Q00013 1 +Growth factor receptor binding 0.3927206210863733 0.5251243027135853 0.5994967826712034 1.0 0.8509635262661505 13 Q9NZ08,O60749 2 +Phospholipid binding 0.3612236918175253 0.515101256172801 0.6064822649662869 1.0 0.8532752098001407 78 Q14108,P50897,Q8WTV0,Q9UJZ1,P07602,Q9Y5X1,O15294,P21796,Q9UM22,P45880,Q8NCC3,P04114,O14773 13 +Myosin v binding 0.4859359844810964 0.5127313200789518 0.6081392778101689 1.0 0.8532752098001407 5 P61026,P61006,Q15907,P20340 4 +Beta n acetylhexosaminidase activity 0.5289983704046866 0.507043577542404 0.6121242425811373 1.0 0.8532752098001407 4 O60502 1 +Nuclear receptor activity 0.6518087855297179 0.5053248206020692 0.6133307124774849 1.0 0.8532752098001407 2 P40763 1 +Retinoic acid binding 0.651808785529717 0.5053248206020657 0.6133307124774874 1.0 0.8532752098001407 2 P11717 1 +Isoprenoid binding 0.651808785529717 0.5053248206020657 0.6133307124774874 1.0 0.8532752098001407 2 P11717 1 +Channel regulator activity 0.3765008144646672 0.4792728433988542 0.6317445388827199 1.0 0.8621603827237119 14 Q96PU5,Q9UNK0,Q13586,O15400 4 +Aminopeptidase activity 0.3842155160961185 0.477682019882631 0.6328765434977299 1.0 0.8621728830927051 13 P55786,Q9UIQ6 2 +Phosphatidylinositol monophosphate phosphatase activity 0.6449387661419987 0.4721955427912482 0.6367872208975223 1.0 0.8664377571053199 3 Q9C0I1 1 +C acyltransferase activity 0.3960457123295591 0.4538058177444515 0.6499685959118302 1.0 0.8669707297338844 11 Q9BWD1 1 +Beta tubulin binding 0.3635835941118578 0.453798890739585 0.6499735820808359 1.0 0.8669707297338844 15 O14737,O75381 2 +Potassium ion transmembrane transporter activity 0.5121041076854026 0.4500657595036326 0.652663025129236 1.0 0.8669707297338844 4 P05023,Q9BXP2 2 +Non membrane spanning protein tyrosine kinase activity 0.4684772065955521 0.4479974313890444 0.6541550503789104 1.0 0.8669707297338844 5 Q9UIG0,P07947,P07948,P19525 4 +Ubiquitin like protein specific protease activity 0.3393630661089726 0.4478150916910819 0.6542866507786456 1.0 0.8669707297338844 27 O00303,Q9BT78,P51665,Q96K76,Q9NUQ7,Q9HBH5 6 +Phosphatidylinositol 3 4 5 trisphosphate binding 0.4098413726124816 0.4418703295568236 0.6585830421995145 1.0 0.8695090052342309 9 Q9H0H5,Q96AC1,Q92538,O15294,Q9BWH2,O43795,P46940,Q8N668 8 +Vitamin d receptor binding 0.4071780045389966 0.4297979326249754 0.6673426368809512 1.0 0.8764798027445618 9 Q9Y2X0,O75448,Q9NPJ6 3 +Dynactin binding 0.6206785137318189 0.4037117960648758 0.6864246642572143 1.0 0.8886257076557985 3 Q8TD16,Q9UNH7 2 +3 hydroxyacyl coa dehydrogenase activity 0.4236103163254427 0.3940568170736353 0.6935390918402291 1.0 0.8943513533518347 7 Q53GQ0 1 +Sulfatide binding 0.6102328964788843 0.3756559570483553 0.7071726847456596 1.0 0.9018438170632852 3 P50897 1 +Metal dependent deubiquitinase activity 0.415894845420131 0.3636061786497294 0.7161521122727474 1.0 0.9059497697412172 7 O00303,P51665 2 +Metallochaperone activity 0.4819819111299017 0.3545877040091168 0.7228984891377994 1.0 0.907760251524502 4 O43819,O75880 2 +Copper chaperone activity 0.4819819111299017 0.3545877040091168 0.7228984891377994 1.0 0.907760251524502 4 O43819,O75880 2 +Isopeptidase activity 0.3948524633380946 0.3445440024243664 0.730437210183124 1.0 0.912711449788454 8 O00303,P51665 2 +Monosaccharide binding 0.3298245011508617 0.3313970764240206 0.7403445729302212 1.0 0.921637913409348 24 O75503 1 +Dopamine receptor binding 0.5902331201545588 0.3245724531483197 0.7455046785815957 1.0 0.9222319457112929 3 P50570 1 +Protein kinase a binding 0.3481705755425759 0.3213296288113124 0.7479606054337 1.0 0.9226153618344538 14 Q9H3P7,Q92667 2 +Microtubule plus end binding 0.3747561708766359 0.3205121957631393 0.7485800867291084 1.0 0.9226153618344538 10 Q13586 1 +Demethylase activity 0.3795302555585364 0.3091102564174274 0.7572376575045512 1.0 0.9283147520442832 9 Q16850 1 +Gtp dependent protein binding 0.4001251986011712 0.3034213934363282 0.7615687440646903 1.0 0.9327847386835504 7 O00203,Q9BZG1,Q13637 3 +Insulin like growth factor binding 0.5629844961240345 0.2654988942283385 0.7906251615798647 1.0 0.9479150264716336 2 P11717 1 +Copper ion binding 0.355071413253533 0.2590639174189653 0.7955859243339014 1.0 0.9507692497376706 11 O75880,O43819,P00403,P35670 4 +Gtpase inhibitor activity 0.4104376113530912 0.2546487576778751 0.7989943970750999 1.0 0.9515204304162715 5 O94813 1 +Nuclear import signal receptor activity 0.3571863550286289 0.2446833557227432 0.8067016165752552 1.0 0.9545852317771482 10 Q9UI26,O00410,Q96P70,P52292 4 +Nucleoside triphosphatase regulator activity 0.3229537494940112 0.2426057830724918 0.808310800799003 1.0 0.9556591238613212 56 Q9Y4G8,Q02818,P80303,P55010,Q5VZ89,O94813,Q14344,Q9Y4F1,A4D1U4,Q9NPQ8,Q9NR50 11 +Voltage gated cation channel activity 0.5465116279069842 0.2308066633982497 0.8174650043505647 1.0 0.9584081138513302 2 P06756 1 +Voltage gated calcium channel activity 0.5465116279069842 0.2308066633982497 0.8174650043505647 1.0 0.9584081138513302 2 P06756 1 +Structural constituent of muscle 0.3843855670245443 0.2266553921782045 0.8206917162494174 1.0 0.9592945719902874 6 P14649,P60660,P67936 3 +Phosphatidic acid binding 0.4346516159693139 0.2240530314815897 0.8227160388217927 1.0 0.9601878705015268 4 Q9Y4G8 1 +Map kinase scaffold activity 0.5361757105943239 0.2107654662858274 0.8330702871078195 1.0 0.968672688846331 2 O60271 1 +Polynucleotide adenylyltransferase activity 0.5358527131783 0.2101608459063348 0.8335421375388399 1.0 0.968672688846331 2 Q9NVV4 1 +Histone h3 methyl lysine 4 demethylase activity 0.5325458144223085 0.1990100391577369 0.8422548915558756 1.0 0.9738125316630752 3 Q9H6W3 1 +Single stranded dna endodeoxyribonuclease activity 0.4224305106658066 0.1948573659792963 0.8455046113692202 1.0 0.9747335309502364 4 P18887,Q92878,P49959 3 +Long chain fatty acyl coa binding 0.5271317829457456 0.1943343108042289 0.8459141215735533 1.0 0.9747335309502364 2 P22307 1 +Spectrin binding 0.3877578065765401 0.1906411835079066 0.8488067221143327 1.0 0.9757279076214496 5 Q13561,P35611 2 +Sterol transfer activity 0.5266279016709443 0.1881112175522859 0.850789467740293 1.0 0.9757279076214496 3 P04114 1 +Rna 7 methylguanosine cap binding 0.3486565231466361 0.1868326621317525 0.8517918371232771 1.0 0.9757279076214496 9 Q6PKG0,Q09161,Q96C86,Q96F07,Q8TEQ6,Q7L576,Q53F19,P52298 8 +Single stranded dna helicase activity 0.3296322634010611 0.1742069858976954 0.8617027955347694 1.0 0.9778319420960304 12 P33991 1 +Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor 0.3808600064662242 0.1726838729614956 0.8628999208594132 1.0 0.9778319420960304 5 P21953,P11177,P08559,P12694 4 +Histone methyltransferase binding 0.3654592496765778 0.1688974933566054 0.8658772708854081 1.0 0.9787106121402618 6 P83916,O95785,P35222,P08238,Q13185 5 +Cyclin dependent protein serine threonine kinase regulator activity 0.3790678781510156 0.1681387136949938 0.8664741537472271 1.0 0.9787106121402618 5 P14635 1 +Flavin adenine dinucleotide binding 0.2898243144308566 0.1617877990837103 0.871472961378895 1.0 0.9793222176673304 31 Q8NE62,P16435,Q9NX74,P49748,O15254,Q8NB78,O00116,Q15392,O95831,P50336,A1L0T0,P00390,Q9UHQ9,Q14534 14 +Ephrin receptor binding 0.358022760816863 0.1591206780197861 0.8735737970721158 1.0 0.9793222176673304 7 Q15375 1 +Carbohydrate binding 0.2955376276385418 0.1580271359666543 0.8744354159652252 1.0 0.9793222176673304 39 Q9NPA0,Q9UBG0,O75503,Q5KU26,O60762,Q32P28 6 +Exodeoxyribonuclease activity 0.3353679858529698 0.1577560022770431 0.8746490695176805 1.0 0.9793222176673304 10 Q9UQ84 1 +Transforming growth factor beta receptor binding 0.502906976744191 0.1554068615677127 0.876500575136913 1.0 0.9793222176673304 2 Q9UNH7 1 +Type i transforming growth factor beta receptor binding 0.502906976744191 0.1554068615677127 0.876500575136913 1.0 0.9793222176673304 2 Q9UNH7 1 +Nadp binding 0.3030930467646541 0.1451995020265409 0.8845533590930981 1.0 0.984282414284967 20 O76062,Q13423,P16435 3 +Translation activator activity 0.4938630490956069 0.1427508085935545 0.8864869881345634 1.0 0.9856287982361432 2 P11940 1 +Cytochrome b5 reductase activity acting on nad p h 0.4970310483140976 0.139405618814462 0.889129632544648 1.0 0.9861519214379564 3 P16435 1 +Galactosyltransferase activity 0.4748347908070752 0.1092198341451206 0.913028129044297 1.0 1.0 3 O43505 1 +Fucosyltransferase activity 0.4625322997416033 0.1064520817553485 0.915223672522522 1.0 1.0 2 Q9Y2G5 1 +Lipid transfer activity 0.3415944104278723 0.1044706729832598 0.9167958404734272 1.0 1.0 6 P04114 1 +Anaphase promoting complex binding 0.4617124394184053 0.0938701351695483 0.9252123177391792 1.0 1.0 3 P53350,Q16763 2 +Nucleobase transmembrane transporter activity 0.4421834625323002 0.0887025969831724 0.929318268579721 1.0 1.0 2 P05141 1 +Oxidative phosphorylation uncoupler activity 0.4421834625323002 0.0887025969831724 0.929318268579721 1.0 1.0 2 P05141 1 +Lipase binding 0.4499361805177181 0.0816170929573623 0.9349512084287676 1.0 1.0 3 P04114 1 +Peptidase activator activity 0.3152642095895829 0.073971813102184 0.9410328136830683 1.0 1.0 9 O76031,Q9UL46,Q9BXK5 3 +P type potassium transmembrane transporter activity 0.4176356589147294 0.0726141216652196 0.9421131889239124 1.0 1.0 2 P05023 1 +Glucocorticoid receptor binding 0.4018087855297142 0.0648976273953053 0.948255509677953 1.0 1.0 2 Q04917 1 +Translation initiation factor activity 0.2761456568502825 0.0646867299051634 0.9484234286945328 1.0 1.0 31 P55010 1 +S methyltransferase activity 0.4287560581583166 0.0630125305037411 0.949756526252268 1.0 1.0 3 Q99707,Q6UX53 2 +Transmembrane transporter binding 0.285105639910324 0.0617922755737699 0.950728254933046 1.0 1.0 26 P21796,P16615 2 +Notch binding 0.3937338501291974 0.0616527895421462 0.950839336889528 1.0 1.0 2 Q13573 1 +Opsonin binding 0.3474466709760848 0.0614647583801573 0.950989080056879 1.0 1.0 4 P35232,P06756,Q07021 3 +Cxcr chemokine receptor binding 0.2635658914728599 0.0448139749562939 0.9642555858799968 1.0 1.0 2 Q96J02 1 +Syntaxin 1 binding 0.3873990306946689 0.0379027388784286 0.9697652293107196 1.0 1.0 3 O75150,O00186 2 +Mitogen activated protein kinase binding 0.3126508106725278 0.0367534242246446 0.970681611019057 1.0 1.0 5 Q9NUL3 1 +Trna guanine methyltransferase activity 0.3121073927781652 0.0359802005834518 0.9712981463763436 1.0 1.0 5 O75648 1 +Insulin receptor binding 0.3037223333338741 0.0246507575378408 0.9803335329223604 1.0 1.0 5 O60749 1 +Complement binding 0.34733441033926 0.0245841298729473 0.9803866780016 1.0 1.0 3 P35232,Q07021 2 +Ww domain binding 0.2999773702829557 0.0199506833970253 0.9840827136726822 1.0 1.0 5 P50570 1 +S acyltransferase activity 0.2828968638861884 0.0012199133456936 0.999026650217375 1.0 1.0 5 O15498,P49327,Q5W0Z9,P36957 4 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..49a55c140f2175505ff264d67962ccd5c9f99248 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 3 kinase regulator activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5alpha androstane 3beta 17beta diol dehydrogenase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 1 adaptor complex binding", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide 1 phosphate binding", "Ceramide 1 phosphate transfer activity", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Choline transmembrane transporter activity", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromatin insulator sequence binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Copper ion transmembrane transporter activity", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix protein binding", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibronectin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyl n acetylgalactosaminyl proteoglycan 4 beta n acetylgalactosaminyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophosphodiester phosphodiesterase activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanosine diphosphatase activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Icosanoid binding", "Identical protein binding", "Igg binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n acetyltransferase activity acting on acetyl phosphate as donor", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Neuregulin binding", "Neurexin family protein binding", "Neurotransmitter binding", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphate ion transmembrane transporter activity", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphorylation dependent protein binding", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Platelet derived growth factor receptor binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein cysteine s stearoyltransferase activity", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase 2b binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein self association", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp n acetylglucosamine transmembrane transporter activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL8A", "ARL8B", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPIF1", "ATRIP", "ATRX", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf35", "C1orf52", "C2CD5", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC22", "CCDC47", "CCDC59", "CCDC6", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA5", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPV", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "COG2", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC19", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLK", "DOLPP1", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GID8", "GIGYF2", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPI", "GPR107", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS4", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1147", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LETMD1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLPH", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LZIC", "M6PR", "MACF1", "MAEA", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NES", "NFS1", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NKRF", "NKTR", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDZD8", "PEBP1", "PECR", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2B", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PWWP2A", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RTCB", "RTF1", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35A4", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPOP", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", 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0.0105883475769395 +Generalized joint laxity 3 12 2.3802539921828094 0.0173007086039134 2.7815533980582523 11.79368932038835 0.6564693612664338 0.4622151090919249 1.854108404410052 1.1421572930726116 0.9213406108825204 0.3139838952541599 0.0120652542122147 0.1263420182810564 0.0299460957191466 0.0294507732567689 0.0446088038944012 +Abnormal visual electrophysiology 7 44 2.3764134061647693 0.0174818641729683 11.310679611650484 49.08009708737864 0.5738496712827478 0.4298926605512212 5.601714588788375 4.822166856762376 1.2686017151039417 0.3684491475281102 0.0384787880097702 0.1520007577137938 0.1642923571168563 0.0237635173186347 0.2653941724334376 +Motor neuron atrophy 2 19 2.353047661564288 0.0186202472428187 5.410194174757281 22.424757281553397 0.8356342611289532 0.3959768073616548 2.754377444710008 1.6813276911909307 0.954775311801755 0.3176984078794489 0.0549135737484515 0.2145132052152406 0.0846927074465841 0.1203869764331773 0.2236139420972091 +Abnormal visual field test 0 5 2.3388969541136 0.019340767179597 1.327669902912621 4.230582524271845 0.1762266305915039 0.415534143350189 1.137153407249188 1.1006338202583732 1.177482986201558 0.3081885114514395 0.2164578169597442 0.0652597674910206 0.1277572387780678 0.290751966651369 0.5020158400168588 +Hypothermia 4 12 2.337476757398221 0.0194144080966527 2.4174757281553396 9.49271844660194 1.0856169578047503 0.2588610618328691 1.611694349619475 1.8201795996814751 1.0634596616937388 0.2538467530049644 0.0069459336161985 0.0053672672920639 0.0013656945298514 0.0001885722773553 0.0006318501388434 +3 methylglutaconic aciduria 5 12 2.323293541535718 0.0201633885412504 4.072815533980583 10.594660194174756 0.3579974396117663 0.4371570089867337 2.2174372584356252 1.5620718849823747 1.1566220028171512 0.333066618505644 0.2692522225630656 1.0 0.1611939416425752 0.0007869115437374 0.0013369974246366 +Impaired vibratory sensation 9 32 2.3187194011873413 0.0204102558572052 7.536407766990291 29.62621359223301 0.76301203268979 0.4693506811924163 3.6948054205684504 4.667704809367026 0.9514363452495296 0.3439929646326011 0.3725441505746414 0.3041527321586795 0.5202388609805813 0.0350926445127817 0.0032173368963242 +Psychomotor deterioration 3 9 2.3164361673796527 0.0205344659287431 3.2645631067961167 8.910194174757281 0.9753014938956188 0.1960965459818884 1.3866235282600423 0.7031088807706056 1.4929387846379636 0.2609606457365817 5.432060717638784e-05 0.0017062060788896 0.0067896670197663 0.0002022933287296 0.0027630263410089 +Hyperventilation 1 6 2.307455709562677 0.0210294286152632 1.5121359223300972 5.842233009708738 0.257199533402791 0.3684899252913141 1.1070595624125217 1.4234045280807717 1.1968077455675237 0.2703462773314473 0.0591475015489903 0.0053672672920639 0.0206800818926893 0.1060727287920157 0.3080842130268088 +Paresthesia 5 20 2.2910285505996657 0.0219617624431651 5.66747572815534 23.635922330097088 0.7476018604198311 0.4719429115693522 2.535880467324221 3.039141242047335 0.8424234714329004 0.3217041155902614 0.0404734839609984 1.0 0.5202388609805813 0.0350926445127817 0.1560553988427572 +Myoclonic spasms 1 6 2.2719995802235946 0.0230865356847802 1.8470873786407769 5.735436893203883 0.4111012021794172 0.4034071629491823 1.317697411431444 1.410916714116348 1.1149340295568837 0.2968871614008488 0.3302973601223983 0.1049896535105009 0.2012104780589677 0.4314443861210575 0.3080842130268088 +Abnormal upper motor neuron morphology 1 9 2.260200353941872 0.0238088189120906 2.104368932038835 10.152912621359222 0.6668580581129538 0.4264480473015415 1.810508789672501 1.2708136152843803 0.93546763978058 0.305632736845798 0.0378207561175528 0.083126337411673 0.1611939416425752 0.0693365470158766 0.2166689846253057 +Nephrotic syndrome 7 20 2.257500753077601 0.0239768024850406 6.691747572815534 26.449029126213592 0.5692557086068671 0.4287880468715059 3.1782986616871702 3.4415823902191023 1.075640445131052 0.3251004953320756 0.0892949185257981 0.377722993581858 0.6174131336984634 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caudate nucleus 0 5 2.2339189575207192 0.0254884059580027 1.2888349514563109 4.283980582524272 0.3751529128205025 0.4147621281846377 1.0481475114547032 1.0836094304135666 1.1513114797047737 0.3142236199023666 0.1886554556893237 0.0561990347849709 0.1105474823156849 0.2550529546148332 0.4498304155532511 +Generalized myoclonic seizure 6 41 2.224183671467219 0.0261360891914392 9.177184466019416 40.04854368932039 0.4529392195590967 0.4207459458757411 3.6022058822892773 4.354728800706526 1.2466313924241157 0.3493918392140687 0.0182650039748019 0.0202112715559422 0.0299900182441488 0.0275802795214073 0.0693581972413881 +Basal ganglia cysts 1 7 2.2232235524090163 0.0262007294372994 1.5436893203883495 6.509708737864078 0.6375864218957229 0.3423964855972016 1.553428397761971 0.5418441296142611 1.195152711044975 0.2990830010801169 0.1147834093059456 0.0331691185540615 0.0660385900079411 0.0113265963942617 0.0419919493306108 +Mental deterioration 30 91 2.221156866627448 0.0263403385151836 26.16990291262136 97.51699029126212 1.0638646072845834 0.3178098854339388 8.217921866043707 8.355116022963852 1.9487627742005753 0.3762024781602087 2.348079532291745e-05 0.0011113418092869 0.0006446045667996 3.065423705947584e-05 0.0001629592932145 +Dysdiadochokinesis 6 14 2.189291440063513 0.0285756641228345 4.157766990291262 15.45388349514563 0.6684839389883598 0.4186205101687726 2.0089273726107977 1.5439545323865935 0.9784437725207784 0.3063164957116248 0.1049906211400749 1.0 0.2685353106225043 0.0415700360883472 0.003914644875648 +Hypoparathyroidism 6 14 2.1881146874927766 0.0286612493065083 3.3907766990291264 12.677184466019416 0.6232545121271337 0.4810116180385506 1.8513213278290024 1.9719301655035288 0.837395541974523 0.306860352889589 0.0888202059650672 0.1305522111527444 0.2467424796819782 0.1552222190730896 0.0023211498250519 +Abnormality of head blood vessel 10 25 2.186526582032689 0.0287771020944456 7.512135922330097 24.881067961165048 0.5951213621611695 0.2501622891395578 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4.207728969627408e-06 +Hepatomegaly 54 174 2.162915365242081 0.0305476897546146 39.728155339805824 169.55582524271844 0.4089837357771489 0.5280564448988146 14.21621812446184 16.25283515367601 1.2317505616434137 0.3902252758923212 0.0162286790425763 0.1135120528803406 0.0337722078107034 0.0004458264736669 1.3888774041701302e-09 +Cardiac conduction abnormality 8 27 2.1575602282532103 0.0309620397115555 7.54126213592233 30.07766990291262 0.9307918135366152 0.3911403090848463 3.486554807604548 3.5456504747498965 0.9289536354013204 0.3216072900435658 0.0591976461210597 0.0627750690965546 0.049541392930243 0.0169357854376417 0.0217147780971135 +Abnormal muscle fiber morphology 18 67 2.128246293717778 0.0333166683867864 17.78640776699029 68.04126213592232 1.263675841483234 0.3649599499596623 6.500784844979595 6.6307423444197315 1.1691802531751734 0.3853191125649093 0.0601400700518201 0.0010040849192341 0.0201087197693027 0.0420042231764413 0.0008014923104584 +Abnormal corpus striatum morphology 4 16 2.1272518891788987 0.0333991598489644 3.783980582524272 16.274271844660195 0.5436026262586074 0.5269340846045785 2.1360147265981855 1.9458739529228473 0.8481478897769046 0.3232524565257521 0.1105465258987554 0.1471951297158956 0.2756599666896902 0.0449350347407693 0.07392944267488 +Left ventricular hypertrophy 8 23 2.126407112129168 0.0334693760898394 7.567961165048544 23.54126213592233 0.6997255266541987 0.4097452846499351 3.537969183053948 3.034709621147107 1.2051726960058406 0.3398649994618895 0.3159020670218361 0.2731012734555347 0.475884211749649 0.2146915796551673 0.1000607998149871 +Progressive neurologic deterioration 7 19 2.123193221230712 0.0337376637827842 6.75 20.466019417475728 0.5813429756502071 0.2930928839947513 2.6727908035631316 1.300228015706032 1.5791549964390388 0.3142214461904322 0.0062670440593274 1.0 0.3432341150980792 0.0036383017284534 0.0009402069411773 +Abnormal electroretinogram 4 29 2.1209523662200405 0.033925811179851 6.859223300970874 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0.037588877934322 1.5631067961165048 5.800970873786408 0.9509293139272904 0.2937126614282376 1.1899245542912666 0.3992700002908385 1.068670600999266 0.275907562675117 0.0098489116445482 0.0424464003246627 0.0032139762811053 0.0188064524051028 0.0675218785318175 +Segmental peripheral demyelination remyelination 3 5 2.0738106424316767 0.0380969003951388 1.6601941747572817 4.737864077669903 1.1231406516527276 0.2457358043386077 1.1021021225411718 1.375663406058269 1.1869683790120098 0.2709829643602553 0.0009918498188417 0.0014481500629001 0.0057815105752346 0.00262770885776 0.0001575214550341 +Increased cerebral lipofuscin 3 5 2.059716720733607 0.039425629978647 3.0970873786407767 5.118932038834951 1.0434065701738664 0.1270836154757583 1.1278862704044743 0.4599818751628888 1.7720117842909846 0.2267161680252343 0.0005549650281771 0.0470522829573702 0.0039921150854813 6.292953854873037e-05 0.0009118158302113 +Lacticaciduria 3 6 2.0586250322975705 0.0395301728520975 1.674757281553398 4.849514563106796 0.7129753583310345 0.3234768766519366 1.205184467740076 1.4436586333991552 1.2463576287305282 0.29112130721695 0.0019745890336275 0.0022827689145391 0.0090253131212995 0.000371706641515 0.0048822579474643 +Ventricular hypertrophy 10 36 2.0580739766040708 0.0395830326575241 10.04126213592233 36.45873786407767 1.1361758135608295 0.3518404639351837 4.440080726024568 4.153106961798495 1.0569836433105884 0.3376234863759063 0.0817928532115666 0.3685774959165274 0.0648492807338132 0.0276263990590475 0.0407161489813638 +Schizophrenia 6 19 2.0561444659548087 0.039768593287464 5.444174757281553 19.50242718446602 0.9817145874838714 0.3473822480141803 2.400301366302062 2.641618717487706 1.084663392230114 0.3211478296747099 0.1573728713678737 1.0 1.0 0.2616785322574622 0.0134528362725409 +Hemianopia 2 8 2.054454916158754 0.0399316826032563 2.0776699029126213 7.611650485436893 0.5790308557992101 0.4109966183023263 1.4034584217287485 1.4877037085527185 1.0055409588864108 0.2887898466516661 0.4175936024449525 0.1389130578490434 0.2613412907301976 0.5329697587184232 0.1889957663081205 +Ventricular preexcitation 2 7 2.048828134085042 0.0404789236616718 2.5145631067961167 6.497572815533981 0.9841118497305948 0.2225227126053997 1.468861772329754 1.5757549992030588 1.3097679632537274 0.2453287763295943 0.0417999766536677 0.0036723611473879 0.0143328298354406 0.0762921742488627 0.0618109910728358 +Supranuclear gaze palsy 6 21 2.048807646716811 0.0404809277510573 5.186893203883495 19.1626213592233 0.8242716574954257 0.3183493558985887 2.2612229396433574 2.139608194404574 1.2188387108542005 0.2935859783151378 0.029336552338356 0.1715759324473242 0.0548237001435711 0.0678108138951911 0.0390278099301106 +Retinal vascular tortuosity 5 14 2.043755301208618 0.0409777269774651 3.495145631067961 14.25728155339806 0.5904651339279154 0.4721906216948602 2.0650761588615536 2.517284017277412 0.91909598108814 0.3171023435283937 0.1882248491254931 0.0204708743585679 0.0733374275738533 0.3067990234802971 0.0707827064406983 +Thin ribs 6 13 2.0401837265955702 0.0413320299599482 3.4101941747572817 12.966019417475728 1.1546097093245242 0.318018636886438 1.686379750034164 1.4240686548069037 0.806693252185275 0.2897104943533539 0.1105465258987554 1.0 0.2756599666896902 0.0449350347407693 0.0045924061823516 +Toe walking 3 23 2.038038593193582 0.0415460734273589 6.740291262135922 22.805825242718445 1.1386089770349623 0.3130572717722256 3.272869930973316 2.572476621751866 1.068544148592376 0.2998505070337083 0.0114109532240053 0.2183067054048652 0.3927678686332497 0.0345596402774107 0.1000707214680032 +Limb ataxia 7 24 2.015304660548878 0.0438727369065079 6.597087378640777 24.114077669902912 0.989869123864314 0.3154216467413447 2.5039369509835696 2.8496458430585005 1.1323309577692284 0.292147514752726 0.0815719560401729 0.2480154974279715 0.4386006499544391 0.0138556470380734 0.0073008402117251 +Abnormality of subcutaneous fat tissue 3 15 2.0040282895734345 0.0450670301099962 3.5315533980582523 14.609223300970871 0.4927453102279533 0.5158508778750083 2.08705546154764 1.590387501977853 0.8250997819958794 0.3082616259597306 0.1757749360267854 0.1913705796369965 0.0678620701894922 0.0901467992310857 0.1636366172223574 +Visual field defect 4 42 2.002140125618748 0.045269663038211 10.441747572815531 43.536407766990294 0.5300405726422278 0.5592030820157294 4.192457959491754 4.4874295525463 0.9433269391526378 0.3481975369092003 0.0905127899419333 0.0042479052183326 0.0109455825152527 0.2429284756089458 0.227435704552848 +Mitochondrial respiratory chain defects 4 6 2.001419549646976 0.0453471956237254 1.8033980582524272 5.177184466019417 1.0048180638921334 0.285673153216041 1.1353491002390874 1.0681459460620504 1.0953831291184488 0.2879410254685434 0.0303360476395803 0.0026008925831016 0.0102498345034834 0.0561137872346343 0.0062633876942655 +Abnormal vascular physiology 10 51 2.0008731191166573 0.0454060650890697 12.74757281553398 50.021844660194176 0.816183607478715 0.4136638745601454 4.907827009322534 5.622165606934028 1.2216480011219424 0.371091913776798 0.1765570271668268 0.2000849887556309 0.2336988302273838 0.057766545834168 0.1315791809179979 +Focal segmental glomerulosclerosis 6 21 2.0008044202068724 0.0454134708935853 5.546116504854369 21.611650485436893 0.6827474585317643 0.4280798303492368 2.9461690553889595 2.0180400455423047 1.030587218054049 0.3284604148463202 0.1757749360267854 0.0188245552589776 0.0678620701894922 0.0901467992310857 0.0187017730028202 +Abnormal pupillary function 3 6 2.0007576350327065 0.0454185149603214 1.7985436893203883 6.25 0.9459174425459445 0.2892194993230557 1.1928988171245156 1.7202745886032773 1.109204161812943 0.2732247962160634 0.0995145929386559 1.0 1.0 0.1724444479617574 0.1889957663081205 +Abnormal metabolic brain imaging by mrs 5 15 1.99982983094496 0.0455186422070166 4.606796116504855 16.54854368932039 0.7235353195513555 0.4019359214719802 2.5477483733613684 2.1144608015049493 1.0143737900681629 0.2966800307492503 0.1161779578639089 0.151306852499084 0.2827159209662828 0.0484311287755044 0.0807266025333323 +Lower limb pain 0 6 1.9961637585120275 0.0459161008608772 1.5825242718446602 4.990291262135922 0.5428874178676697 0.3877045147354496 1.3258027196203157 1.119076818129616 1.1147585770582464 0.3126977330206063 0.2692522225630656 0.083126337411673 0.1611939416425752 0.357118555081159 0.5920308942141137 +Optic disc pallor 18 51 1.996001379800872 0.0459337726082271 14.480582524271844 48.592233009708735 1.02733963234224 0.3801436604957769 5.692535706296588 6.181615230530596 1.3595924408188145 0.3692839687174071 0.004916933376844 0.0002721705512178 0.001125421248196 0.0026574505068975 0.0002380615573444 +Emphysema 2 10 1.9951533205190093 0.0460261603955143 2.516990291262136 8.924757281553399 0.0068659522866356 0.523948054394621 1.7001435318913385 2.017320314617232 0.9111908400421412 0.284926882153668 0.015943639086226 1.0 0.2613412907301976 0.0383377547470353 0.1889957663081205 +Progressive psychomotor deterioration 3 8 1.9915582361193376 0.046419549561447 3.349514563106796 8.320388349514563 0.5379615244672443 0.2176134167318772 1.5053866894387542 0.6226094824456632 1.5848775742530583 0.2457660654605461 0.0009918498188417 1.0 0.1105474823156849 0.00262770885776 0.0019884945269669 +Abnormal circulating citrulline concentration 3 5 1.9850156090853357 0.0471427348902844 1.519417475728155 4.283980582524272 0.9322911204120568 0.2795135602214257 1.0297099461920487 1.0355035731992424 1.235992875942202 0.2843671782204088 0.0174535696320652 0.0014481500629001 0.0057815105752346 0.0328731354880699 0.0019884945269669 +Bone pain 3 22 1.977272947781032 0.0480107858069365 4.975728155339806 22.203883495145632 0.6350188771758896 0.4127751797545932 2.519707411717398 2.310210444333206 1.0375367125895096 0.3016728005813124 0.0632576811314239 0.225839943305071 0.4045619729724357 0.1367305798708485 0.255494622522304 +Hypoglycemic seizures 2 8 1.9714254493521588 0.0486752324822443 2.4854368932038833 6.856796116504855 0.9058299307950756 0.3166741060128459 1.3942606188234674 0.5840745955687526 1.0191247609873073 0.2803355691671325 0.0203954716413504 1.0 0.1191939669275513 0.003355333516566 0.0225979674873623 +Persistent head lag 1 6 1.9691980741923223 0.0489303499601292 2.2597087378640777 6.951456310679611 0.0979834109777058 0.6659849716992147 1.8029177841836248 0.2149120739920257 0.6507803227434458 0.2670073469524342 0.1147834093059456 1.0 0.0660385900079411 0.0113265963942617 0.0419919493306108 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1932962be31a9657e7a1b8dec2d226a78572f668 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 4530, + "title": "Average number of proteins per term", + "value": 23.418984547461367 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..677b553f6a80e963c4a1ae3301c0b181883438ea --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ea3fa59dd0136c02fc0db7d0b62d281f3fb6bbcf --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1369 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cognitive impairment 0.4826534685381656 3.836019678074991 0.000125044393195 0.4324841042537662 0.3473674608423535 159 P00846,Q99720,O43681,Q14108,Q96F07,O75306,Q9BRK0,O95470,P07196,P07602,P00403,P35670,Q9NPL8,P57740,O95831,P03886,Q9Y487,Q9UJS0,P50897,P06865,Q8NHS3,Q9Y2R0,Q13510,Q9BVA1,O15118,Q9H6K4,Q5XKP0,P21964,Q9Y619,P61916,P16278,Q6PGP7,O75381,Q9NZ08,O75503,Q9NR50,Q6DKK2,Q9UBB4,Q96RR1,P06280,Q8NC96,O43819,P54802,P20700,Q10713,Q9UEY8,Q8IY17 47 +Sensorimotor neuropathy 0.6868566512720566 3.3527301521021484 0.0008001868133209 0.9733854525364096 0.3473674608423535 31 P00846,P07196,Q9Y2R0,P07602,Q9NR77,O95831,Q5KU26,P03886,P41440 9 +Progressive visual loss 0.7296585083628703 3.047686624335269 0.0023061028002349 0.9999713027642564 0.3473674608423535 22 P00846,P50897,O75503,P03886,Q9HA77,Q8IY17 6 +Postural tremor 0.7392454521397489 3.0153954699136976 0.0025664438483972 0.999991201549521 0.3473674608423535 20 P00846,Q14108,Q9NR77,Q9H6K4,P03886,Q9HA77,O14773 7 +Bulbar signs 0.8817730761657769 2.9438715258679693 0.0032413452153337 0.999999590013738 0.3473674608423535 11 P00846,Q99720,O43681,P03886 4 +Scotoma 0.8116018356113234 2.872499259895787 0.0040723903289485 0.9999999906285132 0.3473674608423535 13 P00846,Q8NHS3,P03886,Q9H061 4 +Abnormal biliary tract morphology 0.6945506212396518 2.7891140471874047 0.0052852449678229 0.9999999999624616 0.3473674608423535 21 Q9NSD9,O43681,Q14108,P09601,P07602,Q10713,Q5XKP0 7 +Ragged red muscle fibers 0.7073656698994388 2.7875004318386787 0.0053116383485867 0.999999999966713 0.3473674608423535 19 P00846,Q96RR1,Q9H2D1,P00403,Q9BQP7,O95831,Q70HW3,P03886,Q9HA77 9 +Central scotoma 0.8676647935568502 2.7578298490012942 0.0058186476253103 0.9999999999966944 0.3473674608423535 10 P00846,Q8NHS3,P03886,Q9H061 4 +Episodic vomiting 0.7642376267425989 2.74638481929423 0.0060256039886741 0.9999999999987128 0.3473674608423535 14 P00846,P22695,P35914,P00403,P03886 5 +Biliary tract abnormality 0.6565526028871908 2.7352197099887805 0.0062338651548101 0.9999999999995018 0.3473674608423535 25 Q9NSD9,O43681,Q14108,O95202,P09601,P07602,Q10713,Q5XKP0 8 +Clumsiness 0.6843358926436244 2.6861148824683583 0.0072288229039143 0.9999999999999948 0.3473674608423535 20 O43681,Q96RR1,Q13510,P07602,O75503,P35670,Q05086,O43819,Q9NR77,O14773 10 +Abnormality of pulmonary circulation 0.5953181107956258 2.685842431985194 0.0072347197926416 0.9999999999999948 0.3473674608423535 31 O96000,O75844,Q14108,Q9NZ08,P00403,Q8IZA0,P03886,P20674 8 +Abnormal neuron morphology 0.6525374520791868 2.6575100365962583 0.0078720246434906 0.9999999999999996 0.3473674608423535 24 Q99720,Q15165,Q8IY17 3 +Nephropathy 0.6954471912661205 2.650885074483969 0.0080281153517896 1.0 0.3473674608423535 17 Q10713,Q14108,P03886,P06280 4 +Muscle stiffness 0.6721625727253028 2.6504374010446985 0.0080387622673918 1.0 0.3473674608423535 21 P00846,Q9BRK0,Q15392,P07602,P23786,P53985 6 +Slow decrease in visual acuity 0.8696149922802456 2.646666722190736 0.0081289423447385 1.0 0.3473674608423535 9 P00846 1 +Action tremor 0.588746632418433 2.645490773612319 0.0081572511536391 1.0 0.3473674608423535 57 P00846,Q99720,O43681,Q14108,P07602,Q9NR77,P03886,Q9H6K4,Q9HA77,O14773,P41440,Q8IY17 12 +Peripheral demyelination 0.6929572046710096 2.6362789190332343 0.0083820800966514 1.0 0.3473674608423535 17 P00846,O43681,P50570,P07196,P07602,Q9NR77,P03886,P20700 8 +Pain 0.3977544587764173 2.6356716894975447 0.0083970933400336 1.0 0.3473674608423535 168 P00846,Q14108,Q96HY6,Q9BRK0,P07602,P35670,P57740,Q9BZK7,Q70HW3,P50336,P04114,Q9HA77,Q13586,O15269,Q92766,Q9UGP8,Q13510,Q92804,P28070,Q9H6K4,Q03252,Q13423,P21964,Q8N1F7,P50570,Q9NZ08,P50402,Q15800,Q9NUQ7,P42892,O75844,Q15165,Q9BUK6,Q9UNW1,Q96RR1,P06280,P23786,Q9NR77,P20700,P14174 40 +Polyneuropathy 0.6717954711040857 2.6090626001770008 0.0090790631774948 1.0 0.3473674608423535 20 P00846,P03886,P07602 3 +Demyelinating peripheral neuropathy 0.7161703640992372 2.6090059895857665 0.00908056529347 1.0 0.3473674608423535 15 P00846,P41440,P03886,Q9NR77 4 +Abnormal csf protein level 0.7512045325329644 2.564309791964013 0.0103381225606382 1.0 0.3659416441799289 13 O43681,Q16625,P07602,P00403,Q9NR77,P03886 6 +Decreased activity of mitochondrial complex iv 0.6757097994050816 2.5642443228930527 0.0103400729481304 1.0 0.3659416441799289 18 Q9Y2R0,Q70HW3,Q9Y584,Q9HA77,P13073 5 +Elevated pulmonary artery pressure 0.62061351014284 2.5455944115792692 0.0109091859072067 1.0 0.367276418571323 26 O96000,O75844,Q14108,P00403,Q71SY5,Q8IZA0,P03886,P20674 8 +Mitochondrial myopathy 0.565242306066546 2.5306020799521294 0.0113866946093796 1.0 0.3684409041463571 32 O43676,P00846,O96000,Q9BUK6,Q96RR1,Q96CU9,P00403,Q9NPL8,Q8TB37,P03886,Q9Y375,Q53H12,O75380,Q86Y39 14 +Progressive gait ataxia 0.7435533316664111 2.524418955635064 0.0115889723077127 1.0 0.3723265571201321 13 P00846,O43681,Q96RR1,Q05086,P07602,O14773 6 +Amyotrophic lateral sclerosis 0.7430535228712121 2.5218063379200397 0.0116753966532341 1.0 0.3724615974588074 13 Q99720 1 +Impaired proprioception 0.5693014024257224 2.5141871071680044 0.0119307117637483 1.0 0.3761242089408706 41 P00846,Q9Y619,O75298,Q9BRK0,P07196,O43819,P54802,Q9NR77,Q9H6K4,P20700,O14773,P41440 12 +Juvenile onset 0.5671318204593594 2.492564252025179 0.0126824382133079 1.0 0.3761242089408706 42 P16278,Q8NHS3,P07196,Q13510,P50402,P06280,Q9NR77,P54802,O15118,Q9NR50,Q03252,O14773,O75027,P41440,Q8IY17 15 +Personality changes 0.7589311032258357 2.486958547877387 0.0128840410276653 1.0 0.3761242089408706 12 P00403,P03886,P20700,Q9NR50,Q8IY17 5 +Memory impairment 0.5781129959402806 2.483354812997045 0.0130151377826757 1.0 0.3761242089408706 30 O43681,Q9BRK0,Q9NZ08,P07602,P00403,P03886,Q9NR50 7 +Muscle abnormality related to mitochondrial dysfunction 0.5650540421249539 2.479875996485955 0.0131428080842412 1.0 0.3761242089408706 41 O43676,P00846,O96000,Q9BUK6,Q96RR1,Q96CU9,Q9Y2R0,P00403,Q9NPL8,O75648,Q8TB37,P03886,Q9UBX3,Q9Y375,Q53H12,O75380,Q86Y39 17 +Delusions 0.6912422627753133 2.46885293376544 0.0135546912768496 1.0 0.3822362049900276 15 P21964,O43681,P07602,P50336,Q9NR50,Q96DF8,Q9UJS0 7 +Visual loss 0.5653484075497591 2.461359982215647 0.0138411411801389 1.0 0.3822362049900276 47 P00846,P50897,Q8NHS3,P07602,O75503,P03886,Q10713,Q9HA77,O14773,Q8IY17 10 +Abnormal full field electroretinogram 0.8917344715431774 2.4612080598422117 0.0138470039304241 1.0 0.3822362049900276 7 P00846 1 +Abnormal light and dark adapted electroretinogram 0.8917344715431774 2.4612080598422117 0.0138470039304241 1.0 0.3822362049900276 7 P00846 1 +Abnormal cellular phenotype 0.3975359079108618 2.4412593215954552 0.014636140631 1.0 0.3823867306594892 193 P00846,Q9UJW0,Q14108,P02786,O75306,Q9NRW7,P07602,P00403,Q9NPL8,Q9BQP7,Q70HW3,P15586,P03886,Q9NZJ7,Q9Y584,O75880,Q9HA77,Q7KZN9,Q9UJS0,O43676,Q92766,Q9Y2R0,Q13510,P28070,P33991,Q9UBX3,P13073,O43772,P21964,Q9BXW9,O95453,Q4J6C6,Q6PGP7,P09601,O75503,P35914,O00203,O75380,P20674,Q86Y39,O75844,O96000,Q9BV10,Q96RR1,Q96CU9,O75787,P23786,Q9UMS0,O75648,Q9Y375,Q9P0J0,Q96DF8,P14174,Q8TB37,O14773 55 +Horizontal nystagmus 0.6124668272618312 2.4375340855786307 0.0147878199972408 1.0 0.3823867306594892 25 P00846,Q9H061,P07602,O95831,O00203,O14773 6 +Tremor 0.3825973985194569 2.4326393017692545 0.0149892245033744 1.0 0.3823867306594892 163 P61457,P00846,Q99720,O43681,Q14108,Q96F07,O75306,Q9BRK0,P07196,P07602,P35670,O95831,P03886,Q9HA77,O75027,Q9UJS0,Q13510,Q9H6K4,O60762,O75503,Q6DKK2,O14653,Q9UBB4,Q9BUK6,Q96RR1,Q6P4A7,Q05086,Q8NC96,O75787,Q9NR77,P20700,Q10713,O14773,P41440,Q8IY17 35 +Abnormal speech prosody 0.8398179332596822 2.4096460035992098 0.0159680055238653 1.0 0.3939744728872909 8 P00846 1 +Impaired vibration sensation in the lower limbs 0.6796100220688958 2.40263528060406 0.016277412712965 1.0 0.398576646430981 15 P00846,O75298,Q9BRK0,O43819,Q9NR77 5 +Generalized joint laxity 0.7378852345017747 2.3802539921828094 0.0173007086039134 1.0 0.4101957212173693 12 Q9Y487,Q9UHX1,Q8NCH0 3 +Abnormal visual electrophysiology 0.5538689404605769 2.3764134061647693 0.0174818641729683 1.0 0.4101957212173693 44 P00846,O43681,P50897,P07602,O75503,Q53H12,Q8IY17 7 +Motor neuron atrophy 0.636153438768145 2.353047661564288 0.0186202472428187 1.0 0.4245308877592851 19 Q99720,Q15165 2 +Hypothermia 0.7295242835379903 2.337476757398221 0.0194144080966527 1.0 0.4253082535453389 12 O43772,P00846,Q5XKP0,P03886 4 +3 methylglutaconic aciduria 0.7267616196592142 2.323293541535718 0.0201633885412504 1.0 0.4370342109658588 12 P35914,Q9NVI7,Q9H6K4,Q53H12,Q5XKP0 5 +Impaired vibratory sensation 0.5386721499860602 2.3187194011873413 0.0204102558572052 1.0 0.4402783763482844 32 P00846,Q9Y619,O75298,Q9BRK0,P07196,O43819,Q9NR77,P20700,O14773 9 +Psychomotor deterioration 0.7954646036653366 2.3164361673796527 0.0205344659287431 1.0 0.4408584391336809 9 Q9Y487,P50897,P07602 3 +Hyperventilation 0.8767114947758035 2.307455709562677 0.0210294286152632 1.0 0.4472823995702008 6 P00846 1 +Paresthesia 0.621218654311506 2.2910285505996657 0.0219617624431651 1.0 0.4614499656138933 20 Q9NZ08,P06280,Q9NR77,P54802,Q9H6K4 5 +Myoclonic spasms 0.8680369778626091 2.2719995802235946 0.0230865356847802 1.0 0.4695890357244637 6 P00846 1 +Abnormal upper motor neuron morphology 0.7831357292287684 2.2602003539418716 0.0238088189120906 1.0 0.4739280889616634 9 Q99720 1 +Nephrotic syndrome 0.6159942185440836 2.2575007530776015 0.0239768024850406 1.0 0.4739280889616634 20 Q8N1F7,Q14108,Q9BT22,O95470,P06280,Q8NCH0,Q03252 7 +Abnormal retinal artery morphology 0.6086097288387681 2.2440499768871627 0.0248291859647302 1.0 0.4848112604320178 21 P00846,P16278,P06865,P07602,P03886 5 +Optic neuropathy 0.5774001518475975 2.2415994262171264 0.0249872731010036 1.0 0.4858040650109299 26 O43676,P00846,O96000,Q96CU9,Q9NPL8,Q8TB37,P03886,P04114,Q9Y375,Q9P0J0,O75380,Q86Y39 12 +Airway obstruction 0.6513022513519605 2.2392853291758157 0.0251373568348254 1.0 0.4866334464177744 15 O75844,P21964,P16435,Q96HY6,Q92766,P09601,P06280 7 +Generalized myoclonic seizure 0.5338852629080977 2.224183671467219 0.0261360891914392 1.0 0.4963292259974722 41 P00846,P16278,Q8NHS3,P07602,P03886,Q9HA77 6 +Basal ganglia cysts 0.8345773028239208 2.2232235524090163 0.0262007294372994 1.0 0.4963292259974722 7 P00846 1 +Mental deterioration 0.521712889668901 2.2211568666274477 0.0263403385151836 1.0 0.4963292259974722 91 P00846,O43681,Q14108,Q96F07,O75306,O95470,P07602,P00403,P35670,Q9NPL8,P03886,Q9Y487,P50897,P06865,Q8NHS3,Q13510,O15118,Q5XKP0,P21964,P61916,P16278,O75503,Q9UBB4,Q96RR1,Q8NC96,O43819,P54802,P20700,Q10713,Q8IY17 30 +Dysdiadochokinesis 0.6621250971869267 2.189291440063513 0.0285756641228345 1.0 0.499290050916357 14 Q9BUK6,O75503,P20700,Q6DKK2,O75027,P41440 6 +Hypoparathyroidism 0.6619164868718008 2.1881146874927766 0.0286612493065083 1.0 0.499290050916357 14 P21964,Q92766,P00403,Q08J23,P03886,Q96DF8 6 +Abnormality of head blood vessel 0.5764322343283212 2.186526582032689 0.0287771020944456 1.0 0.499290050916357 25 P00846,P21964,P16278,P06865,Q92766,P07602,Q13510,P10619,P03886,P04114 10 +Pendular nystagmus 0.825834062741149 2.1862102630977103 0.0288002257516766 1.0 0.499290050916357 7 P00846,P49902 2 +Abnormality of corneal stroma 0.679739669645337 2.184021812420674 0.0289606452855746 1.0 0.499290050916357 13 P16278,Q16625,Q13510,P04114,O43505,Q9Y5Z9 6 +Hemiparesis 0.6131089940878707 2.179308803496139 0.0293087356763084 1.0 0.499290050916357 18 Q9NZ08,P35914,P00403,P03886,O43791 5 +Retinal telangiectasia 0.884263578766898 2.166792642653971 0.0302506687034225 1.0 0.5069825611127695 5 P00846 1 +Decreased activity of mitochondrial complex i 0.5255626449897057 2.16576145327459 0.0303294203226403 1.0 0.5069825611127695 39 O43676,O96000,Q9Y375,Q96CU9,Q9NPL8,Q70HW3,O75380,P03886,Q9UBX3,Q9Y584,O75648,Q8TB37,Q9HA77,Q86Y39 14 +Hepatomegaly 0.3715967012810417 2.162915365242081 0.0305476897546146 1.0 0.5087538036338394 174 P00846,Q9UJW0,Q14108,Q96HY6,Q6NUQ1,O75306,Q9NRW7,P07602,P31751,P35670,Q9NPL8,P15586,P03886,O75880,Q9UJS0,O43676,Q9UP83,Q9BT22,Q9UGP8,Q13510,P28070,Q9NVI7,O15118,P33991,O60762,Q96A33,O43772,Q9Y619,P61916,P16278,O95453,Q6PGP7,O75381,Q16625,P09601,P35914,O00203,O75380,P20674,O75431,P50416,Q86Y39,O96000,Q96CU9,Q9HC07,P83436,O75787,P23786,P54802,O75648,Q9Y375,Q10713,P14174,Q8TB37 54 +Cardiac conduction abnormality 0.558741111912816 2.1575602282532103 0.0309620397115555 1.0 0.5100292359758057 27 O43772,P00846,P04899,P00403,P06280,P23786,O43819,P03886 8 +Abnormal muscle fiber morphology 0.527514967129054 2.128246293717778 0.0333166683867864 1.0 0.5210181226356453 67 O43676,P00846,Q99720,P50570,Q9BUK6,Q96RR1,Q9H2D1,P07196,Q9HA77,P50402,P00403,P61978,P23786,Q9BQP7,O95831,Q70HW3,P03886,Q13586 18 +Abnormal corpus striatum morphology 0.6124382215216949 2.1272518891788987 0.0333991598489644 1.0 0.5210181226356453 16 P00846,O95831,Q9BVA1,O43819 4 +Left ventricular hypertrophy 0.5800299900502105 2.1264071121291677 0.0334693760898394 1.0 0.5210181226356453 23 Q96RR1,O75208,P00403,P06280,O75787,P03886,O75880,O75431 8 +Progressive neurologic deterioration 0.5999099230626694 2.123193221230712 0.0337376637827842 1.0 0.5213983296005616 19 O43681,P16278,P07602,P54802,P20700,Q10713,Q5XKP0 7 +Abnormal electroretinogram 0.5390344900988965 2.1209523662200405 0.033925811179851 1.0 0.5213983296005616 29 P00846,Q53H12,P50897,Q8IY17 4 +Fluctuations in consciousness 0.8313798777140963 2.120527733195741 0.0339615652752107 1.0 0.5213983296005616 6 O43819,P03886,P00403,Q9UJS0 4 +Abnormal lower motor neuron morphology 0.8097949450257655 2.117889892763944 0.0341843937950037 1.0 0.5213983296005616 7 Q99720 1 +Kinetic tremor 0.5128498407773289 2.1003517527943747 0.0356979098462642 1.0 0.5280146074049664 33 O43681,Q14108,P41440,Q8IY17 4 +Dementia 0.523769715969073 2.091544461704022 0.0364792851443829 1.0 0.5280146074049664 55 P00846,O43681,Q14108,P06865,P07602,O15118,P03886,Q9Y487,Q8IY17 9 +Reduced tendon reflexes 0.3617240336609544 2.089248214870157 0.0366853852952326 1.0 0.5280146074049664 163 P00846,Q99720,O43681,Q96F07,P07196,P07602,Q9BQP7,O95831,Q71SY5,P50336,P03886,P04114,O43505,Q9HA77,Q13586,O15269,Q9BT22,Q13510,Q9BQT8,Q9H6K4,P50570,O95453,O75381,P50402,P35914,P61978,O14653,P50416,Q9UBB4,Q9BUK6,Q96RR1,P83436,Q8NC96,O75787,Q9NR77,P54802,O43819,Q10713,P41440,Q8IY17 40 +Blurred vision 0.864103662477017 2.0858740543532166 0.0369900330880019 1.0 0.5280146074049664 5 P00846 1 +Macrovesicular hepatic steatosis 0.8015418738857185 2.082523135390867 0.0372947119238853 1.0 0.5280146074049664 7 P23786,O75648,O75431,Q5XKP0 4 +Frequent falls 0.5148570894076518 2.0823841217420713 0.037307397609154 1.0 0.5280146074049664 38 P00846,O43681,P07602,Q13510,O43819,Q9NR77,Q13586 7 +Temperature instability 0.7654833929558882 2.081199988320357 0.037415604630683 1.0 0.5280146074049664 8 Q8N3U4,P07602,P20700 3 +Premature rupture of membranes 0.8215141377180586 2.079309876468886 0.037588877934322 1.0 0.5285773830054943 6 Q9Y487 1 +Segmental peripheral demyelination remyelination 0.8611130619598338 2.0738106424316767 0.0380969003951388 1.0 0.5293833091717141 5 P00846,P03886,Q9NR77 3 +Increased cerebral lipofuscin 0.857623877535343 2.059716720733607 0.039425629978647 1.0 0.532143552115799 5 O75503,P50897,P07602 3 +Lacticaciduria 0.8165801679460314 2.0586250322975705 0.0395301728520975 1.0 0.532143552115799 6 P00846,P03886,Q9BQT8 3 +Ventricular hypertrophy 0.5103775562369081 2.0580739766040708 0.0395830326575241 1.0 0.532143552115799 36 O43772,O75844,Q9BV10,P00403,P06280,O75787,P23786,P03886,O75880,O75431 10 +Schizophrenia 0.5895122265313378 2.0561444659548087 0.039768593287464 1.0 0.532143552115799 19 P21964,O43681,P16615,Q9BUK6,Q92766,P07602 6 +Hemianopia 0.7595568027843587 2.054454916158754 0.0399316826032563 1.0 0.532143552115799 8 P03886,P00403 2 +Ventricular preexcitation 0.793709879713587 2.048828134085042 0.0404789236616718 1.0 0.532143552115799 7 P00846,P03886 2 +Supranuclear gaze palsy 0.5791040946848335 2.048807646716811 0.0404809277510573 1.0 0.532143552115799 21 Q99720,P61916,Q96RR1,P07602,O15118,Q9UEY8 6 +Retinal vascular tortuosity 0.6365361766690618 2.043755301208618 0.0409777269774651 1.0 0.532143552115799 14 P21964,P00846,Q92766,P03886,Q96DF8 5 +Thin ribs 0.653530493637164 2.0401837265955702 0.0413320299599482 1.0 0.532143552115799 13 O75844,Q9Y619,P50570,O95831,Q32P28,O75431 6 +Toe walking 0.5672067555186713 2.038038593193582 0.0415460734273589 1.0 0.532143552115799 23 Q99720,O43681,P07602 3 +Limb ataxia 0.5583368115514584 2.015304660548878 0.0438727369065079 1.0 0.552065272740225 24 Q14108,O75298,P07196,Q9NR77,Q10713,O14773,P41440 7 +Abnormality of subcutaneous fat tissue 0.6114586370633152 2.0040282895734345 0.0450670301099962 1.0 0.560324590211373 15 O75844,Q9Y487,O75431 3 +Visual field defect 0.508133082300362 2.0021401256187477 0.045269663038211 1.0 0.560324590211373 42 P00846,Q8NHS3,P03886,Q9H061 4 +Mitochondrial respiratory chain defects 0.8029931730830362 2.001419549646976 0.0453471956237254 1.0 0.560324590211373 6 Q4J6C6,P00846,O75648,P03886 4 +Abnormal vascular physiology 0.5123683481428066 2.0008731191166573 0.0454060650890697 1.0 0.560324590211373 51 O96000,O75844,Q14108,Q9NZ08,P00403,P06280,Q71SY5,Q8IZA0,P03886,P20674 10 +Focal segmental glomerulosclerosis 0.571945175720844 2.0008044202068724 0.0454134708935853 1.0 0.560324590211373 21 Q8N1F7,Q14108,O95470,P00403,P03886,O75431 6 +Abnormal pupillary function 0.8028364545346846 2.0007576350327065 0.0454185149603214 1.0 0.560324590211373 6 Q9NR77,Q13586,P07602 3 +Abnormal metabolic brain imaging by mrs 0.6107570383843487 1.9998298309449596 0.0455186422070166 1.0 0.560324590211373 15 O75306,P07602,P00403,O43819,P03886 5 +Optic disc pallor 0.5118101900953544 1.9960013798008716 0.0459337726082271 1.0 0.5619905838050671 51 O43676,P00846,O96000,Q9H061,Q9BUK6,Q13277,Q8NHS3,Q96CU9,Q9NPL8,Q8WWY3,O95831,Q8TB37,P03886,Q9H6K4,Q9Y375,Q10713,O75380,Q86Y39 18 +Emphysema 0.7049308867099535 1.9951533205190095 0.0460261603955143 1.0 0.5619905838050671 10 Q9NSD9,P06280 2 +Progressive psychomotor deterioration 0.745690142723445 1.9915582361193376 0.046419549561447 1.0 0.5637548512422385 8 O43681,P07602,P16278 3 +Abnormal circulating citrulline concentration 0.8392149987619099 1.9850156090853353 0.0471427348902844 1.0 0.5694842374746357 5 P00846,P03886,Q9UJS0 3 +Bone pain 0.5636207315020382 1.977272947781032 0.0480107858069365 1.0 0.576893527070086 22 Q14108,P07602,Q9UNW1 3 +Hypoglycemic seizures 0.7412722029086793 1.9714254493521588 0.0486752324822443 1.0 0.5775578853521925 8 Q13423,P31751 2 +Persistent head lag 0.7953771492939598 1.9691980741923223 0.0489303499601292 1.0 0.5775578853521925 6 Q9NSD9 1 +Poor eye contact 0.5026146682574372 1.9549972895499104 0.0505833901897618 1.0 0.5892327683588713 42 O43676,O96000,Q96RR1,Q9UHX1,Q96CU9,Q9NPL8,Q5KU26,Q8TB37,P03886,O75746,Q9Y375,Q9P0J0,O75380,Q5XKP0,Q86Y39 15 +Mania 0.6381834011201947 1.954868651898821 0.0505985754727595 1.0 0.5892327683588713 13 P21964,P16615,Q92766,P00403,P03886,Q9UJS0 6 +Arteriosclerosis 0.6202448453422218 1.949852717081615 0.0511936761287656 1.0 0.593339415169655 14 O75844,P38435,P16278,Q13510,O15118,P04114 6 +Abnormal acetabulum morphology 0.5802482265737875 1.9474371934003665 0.051482342655293 1.0 0.593339415169655 17 P16278,Q6NUQ1,Q9NR45,O00203,O75718,Q9Y584 6 +Abnormal circulating cholesterol concentration 0.4943226972941283 1.9458816112047916 0.0516689623207504 1.0 0.593339415169655 33 P61916,Q9BV10,P37268,Q15392,P07602,P50402,P57740,Q9NVI7,Q15800,O75431,P04114,Q9NZJ7,Q8N511,Q9UJS0 14 +Cogwheel rigidity 0.7882274591364897 1.938848734142828 0.0525197599405409 1.0 0.5988379246833877 6 P00846,O75787 2 +Abnormal peripheral myelination 0.5077591172107409 1.9349978524229443 0.0529905592199215 1.0 0.5988379246833877 30 P00846,O43681,P07196,P07602,Q9NR77,P03886,P20700,O15269 8 +Delayed cranial suture closure 0.5146747133823814 1.931486950404346 0.0534228615712573 1.0 0.5990236705886031 29 O75844,P16435,O75381,Q08J23,Q8NCH0,O75718,Q9Y487,O75431 8 +Hyperlipidemia 0.4923993221220638 1.9297079859317072 0.0536430299104673 1.0 0.6000072234430048 33 O75844,O95470,P22830,P50402,P31751,P06280,P23786,P28070,P50416,O75431,Q9UJS0 11 +Abnormality of the parathyroid gland 0.569525302105863 1.9258813418155527 0.0541191916854417 1.0 0.6038422126479094 19 P21964,Q92766,P00403,Q08J23,P03886,Q96DF8 6 +Myoclonic seizure 0.5038491286249915 1.9204623933897709 0.0547995189754693 1.0 0.607489441740623 53 P00846,P16278,Q8NHS3,P07602,Q13510,Q5XKP0,O75503,P03886,Q9HA77 9 +Dyslexia 0.7833187639168864 1.917955990527807 0.055116591734083 1.0 0.607489441740623 6 Q9H6K4 1 +Abnormal delivery 0.563654488360572 1.9145555903392812 0.0555492032847304 1.0 0.6095744428005445 20 O75844,Q9Y619,P33991,O75718,Q9Y487 5 +Retinopathy 0.5112640753125569 1.904667324918108 0.0568233289789144 1.0 0.6095744428005445 29 P07437,P00846,Q5JRA6,P52732,O95202,Q8NHS3,Q9NZ08,O43819,O60762,P51648,Q9Y375 11 +Basal ganglia gliosis 0.7260921812036896 1.9019068948143276 0.0571833276535869 1.0 0.6095744428005445 8 P00846 1 +Myoclonus 0.4907824087721474 1.9006832144840304 0.0573435184574668 1.0 0.6095744428005445 90 P00846,Q14108,P50897,Q9UNW1,P07602,O75503,Q13510,P35914,O14653,Q8NC96,P03886,Q9UBX3,Q10713,Q9HA77,O14773,P13073 16 +Anorexia 0.5299901378718247 1.8960894940035984 0.0579482115829601 1.0 0.6095744428005445 26 Q14108,Q9NZ08,P06280,P35914,Q13423 5 +Centrocecal scotoma 0.8859279248495484 1.8959592762394544 0.0579654297073484 1.0 0.6095744428005445 4 P00846 1 +Loss of speech 0.5685848656652351 1.8949573259097945 0.0580980554742596 1.0 0.6095744428005445 18 O43681,O15118,P50897 3 +Rigidity 0.5002625539256598 1.894704188839506 0.0581316024922373 1.0 0.6095744428005445 51 P00846,O43681,Q96F07,P52732,P16278,Q9BRK0,Q96RR1,Q96CU9,Q15392,P07602,Q8NC96,O75787,Q9H6K4,Q9NZJ7 14 +Osteoarthritis 0.66536244888679 1.893178501967034 0.0583341353196662 1.0 0.610285526554476 11 O75844,Q9NUQ7,Q96HY6,Q14108 4 +Optic atrophy 0.3567685889763375 1.89009745435444 0.0587449275231635 1.0 0.611757521103289 177 P00846,O43681,Q96F07,P07602,P00403,Q8WWY3,P03886,O43505,Q7KZN9,P50897,Q9H061,Q92766,Q8NHS3,Q9NVI7,Q9H6K4,Q5XKP0,P21964,P16278,O75381,P51572,Q96PU5,Q5KU26,Q9NR50,Q9UNW1,O95202,P06280,Q8NC96,O43819,Q96TA2,Q9P0J0,P49902,P41440,Q8IY17 33 +Symptomatic seizures 0.7033789665125161 1.88714850877078 0.0591403537151886 1.0 0.614462849380286 9 Q13423,P31751 2 +Thoracic scoliosis 0.6431665072781159 1.8826645956303247 0.0597458363259122 1.0 0.6170494893337486 12 Q9UHX1 1 +Abnormal astrocyte morphology 0.5912785740327448 1.8825054053824868 0.0597674266557599 1.0 0.6170494893337486 15 P00846 1 +Abnormal pleura morphology 0.6086232006899378 1.8822804113831049 0.0597979527190983 1.0 0.6170494893337486 14 Q14145,Q9NZ08,Q8NCH0 3 +Arthralgia 0.4932111041172494 1.878582596922694 0.0603015092637642 1.0 0.6194094094047768 31 Q96HY6,P14174,Q9NZ08,Q13510,P06280,P28070,Q15800,P04114,Q03252,Q9NUQ7 10 +Muscle fiber inclusion bodies 0.7013796051958399 1.8775930569339976 0.0604368562818788 1.0 0.6194094094047768 9 O43676,P07196 2 +Abnormal auditory evoked potentials 0.7535156464781112 1.873894623389944 0.0609449506773871 1.0 0.6232068319832139 7 P07196,P07602,Q9NZJ7,P20700 4 +Hypocholesterolemia 0.6992314646710421 1.86731570840618 0.0618575130399732 1.0 0.6284741880273905 9 Q9BV10,P37268,P07602,Q9NVI7,Q15800 5 +Glomerulopathy 0.6988411875866232 1.8654473025736795 0.0621187322387313 1.0 0.6284741880273905 9 Q14108,P06280 2 +Abnormality of krebs cycle metabolism 0.8096087325447612 1.8636985256964345 0.0623640525579878 1.0 0.6284741880273905 5 P00846 1 +Aortic valve stenosis 0.6774713782028486 1.859414728270974 0.0629683757487395 1.0 0.6319416122849328 10 P16278 1 +Abnormal renal tubule morphology 0.5509776374021942 1.8588058725774264 0.0630546597688277 1.0 0.6319416122849328 21 P23786,P00846,P03886,P06280 4 +Increased bone mineral density 0.5546760483308774 1.85444878171116 0.0636749813036687 1.0 0.6354698669968191 20 Q13126,P54802,Q14108 3 +Deep palmar crease 0.6577328991426248 1.8536675736710235 0.0637867335502793 1.0 0.6354698669968191 11 Q9Y487,Q9BZK7,O75431 3 +Decerebrate rigidity 0.8716821486127002 1.840629968438772 0.0656758029568305 1.0 0.649588182083935 4 O43681,P16278 2 +Abnormal left ventricle morphology 0.5216643204619024 1.8341290164272857 0.0666348451204095 1.0 0.6532032703867634 26 Q96RR1,O75208,P00403,P06280,O75787,P03886,O75880,O75431 8 +Cerebral calcification 0.4877293736234068 1.8332710199214988 0.0667622768629296 1.0 0.6532032703867634 31 Q9NSD9,Q16625,P00403,O00584,P23786,P03886 6 +Purpura 0.5456745437389907 1.8225646108311335 0.0683693596503944 1.0 0.6589642536516744 21 P21964,P38435,Q16625,Q9BZK7,Q8NCH0,Q13586 6 +Nemaline bodies 0.8625003170870743 1.8048328206321895 0.071100846815415 1.0 0.6674378133020242 4 O43676 1 +Abnormal brainstem mri signal intensity 0.533655024509613 1.8029017604294 0.0714036444941643 1.0 0.6674378133020242 23 O43676,O96000,Q96CU9,Q9NPL8,O95831,Q8TB37,P03886,Q9Y375,O75380,Q86Y39 10 +Leber optic atrophy 0.993540051679586 1.802626880940261 0.0714468324577954 1.0 0.6674378133020242 2 P00846 1 +Retinal arterial tortuosity 0.993540051679586 1.802626880940261 0.0714468324577954 1.0 0.6674378133020242 2 P00846 1 +Multiple glomerular cysts 0.993540051679586 1.802626880940261 0.0714468324577954 1.0 0.6674378133020242 2 P00846 1 +Low plasma citrulline 0.993540051679586 1.802626880940261 0.0714468324577954 1.0 0.6674378133020242 2 P00846 1 +Abnormal circulating non proteinogenic amino acid concentration 0.7373466272339655 1.802595848697566 0.0714517094639177 1.0 0.6674378133020242 7 P00846,P03886,Q9UJS0 3 +Mitochondrial inheritance 0.7947964494404383 1.8024770700175567 0.0714703791610384 1.0 0.6674378133020242 5 P00846,P03886 2 +Abnormal circulating pyruvate family amino acid concentration 0.5328166661345922 1.7969550660382976 0.0723427535198708 1.0 0.671542363616834 23 O96000,P00846,P22695,P03886,P20674,Q5XKP0,Q9P0J0 7 +Stroke like episode 0.7358210823461822 1.7958420929901775 0.072519634127095 1.0 0.6718076535700217 7 P03886,P00403 2 +Abnormal basal ganglia mri signal intensity 0.4753839902984499 1.7940981164194834 0.0727975096518347 1.0 0.6720433869670915 32 Q9P0J0,P00846,P03886,P16278 4 +Neoplasm of the male external genitalia 0.7027133919488411 1.7938207195838756 0.0728417887419077 1.0 0.6720433869670915 8 Q13423 1 +Basal ganglia calcification 0.7530100895617828 1.787963952371171 0.0737818238115748 1.0 0.6779546893842475 6 P03886 1 +Slurred speech 0.643794539639853 1.781062901562257 0.0749021754375298 1.0 0.6854228441567995 11 Q9Y487 1 +Acetabular dysplasia 0.6991661220738001 1.7773149049937012 0.0755164426702461 1.0 0.688308823533632 8 P16278,Q9Y584 2 +Neck muscle weakness 0.5899688326899258 1.7728174285135267 0.0762589644833824 1.0 0.6898414605572998 14 Q99720 1 +Arthritis 0.4796534789062072 1.7628269198295945 0.0779296856614986 1.0 0.6898414605572998 41 O75844,P21964,Q96HY6,Q14108,Q92766,Q9NZ08,Q13510,P06280,P10321,P28070,P14174,Q9NUQ7 12 +Abnormal endocrine physiology 0.7829989946016367 1.7534767357296048 0.079520209424732 1.0 0.6946881803445009 5 P16435,Q13423 2 +Deep plantar creases 0.7449393091664951 1.7530693562528283 0.0795901027811911 1.0 0.6946881803445009 6 Q9Y487,Q9BZK7 2 +Infantile spasms 0.4699503006233325 1.7477661399904536 0.0805045307297713 1.0 0.6978266035383037 32 P00846,P03886,Q13510 3 +Hammertoe 0.542048535743607 1.7439000937754667 0.0811765122904215 1.0 0.6978266035383037 19 Q9NR77,Q99720 2 +Joint subluxation 0.7800746819870549 1.7412988048599989 0.0816312155998584 1.0 0.6978266035383037 5 P16278 1 +Abnormality of the nasolabial region 0.741919842601862 1.7399852212917029 0.0818616130160148 1.0 0.6978266035383037 6 Q9Y487 1 +Prominent nasolabial fold 0.741919842601862 1.7399852212917029 0.0818616130160148 1.0 0.6978266035383037 6 Q9Y487 1 +Hypoplasia of the musculature 0.7788679944101462 1.7362700799195367 0.0825160910057252 1.0 0.6981481070044275 5 Q9Y487 1 +Distal peripheral sensory neuropathy 0.7782236864418832 1.7335841414797792 0.0829918962737377 1.0 0.6981481070044275 5 P03886 1 +Babinski sign 0.4738397617979785 1.7271613071022438 0.0841386977068707 1.0 0.7034667176767262 90 P00846,Q99720,O43681,Q9BRK0,P07196,P07602,O95831,O00400,Q9H6K4,Q6DKK2,O75298,O75787,P49902,Q9NR77,P20700,Q8TB37,O14773,P41440,Q8IY17 19 +Excessive wrinkled skin 0.6883889540572344 1.7270006816706611 0.084167541055361 1.0 0.7034667176767262 8 Q9Y487,Q9BZK7 2 +Choreoathetosis 0.4669419507877573 1.7220304532892403 0.0850640020449093 1.0 0.7073989601755964 32 Q9P0J0,P00846,Q5XKP0,Q9H6K4 4 +Hypotension 0.5172241230942847 1.7205566692410752 0.0853313020434367 1.0 0.7073989601755964 24 O43772,O43681,P07602,P35914,P49366,Q13423 6 +Fever 0.4815548792811478 1.7158585579889505 0.0861879333283563 1.0 0.7073989601755964 74 P00846,Q9NZ08,Q9HC07,P07602,P00403,Q13510,P35914,P06280,Q9BZK7,P28070,P23786,P03886,Q9NR77,Q9NR50,P14174,Q13586 16 +Eeg with spike wave complexes 0.5803118824746923 1.7156786532652002 0.0862208739005112 1.0 0.7073989601755964 14 Q14108 1 +Abnormal nasal mucosa morphology 0.7733494796386362 1.7132456529880615 0.0866673560162305 1.0 0.7073989601755964 5 Q03518,Q13432 2 +Abnormal sella turcica morphology 0.7355867316357301 1.7124913050493504 0.0868061656146759 1.0 0.7073989601755964 6 P16278 1 +Abnormal caudate nucleus morphology 0.6478124956917362 1.7105919646091292 0.0871564633697667 1.0 0.7073989601755964 10 P00846,Q9BVA1,O43819 3 +Nonketotic hypoglycemia 0.7723720634528515 1.7091631435080563 0.0874207338604282 1.0 0.7073989601755964 5 P31751,P35914 2 +Aplasia hypoplasia of the femur 0.5458713747040109 1.7090469324063744 0.0874422563198107 1.0 0.7073989601755964 16 Q9Y2D4,Q96HY6,Q99575,Q9BV10,Q9NR45,O95831,Q9UHX1,O75431 8 +Abnormal circulating progesterone level 0.8373536021248749 1.706277863792343 0.087956357517535 1.0 0.7073989601755964 4 Q9NR50 1 +Decreased circulating progesterone 0.8373536021248749 1.706277863792343 0.087956357517535 1.0 0.7073989601755964 4 Q9NR50 1 +Tetraplegia 0.610658307852074 1.7054333334983385 0.0881136359437559 1.0 0.7073989601755964 12 O95831,O43681,Q13423 3 +Abnormal mitochondria in muscle tissue 0.5198864467587996 1.7048110411649542 0.0882296716333801 1.0 0.7073989601755964 23 O43676,O96000,Q96CU9,P00403,Q9NPL8,Q8TB37,P03886,Q9Y375,O75380,Q86Y39 10 +Ascites 0.5234968692831666 1.6985205126635805 0.0894095645130106 1.0 0.7111271110681074 22 Q9NSD9,Q14108,O15118 3 +Exercise intolerance 0.4660825560042613 1.6973180211868415 0.0896365519690705 1.0 0.7111271110681074 34 Q9NSD9,Q9H2D1,Q9Y2R0,P00403,P23786,P03886,Q53H12,Q8NFF5 8 +Abnormality of lipoprotein cholesterol concentration 0.5603811547182882 1.693452397112877 0.0903693885464682 1.0 0.7153459020959585 15 P37268,P50402,Q15800,Q8N511,Q9UJS0 5 +Abnormality of temperature regulation 0.4660726567800572 1.691658069707151 0.0907111875361534 1.0 0.7153459020959585 95 P00846,P07602,P00403,P57740,Q9BZK7,Q03001,P03886,Q13586,Q13510,P28070,Q5XKP0,O43772,Q8N1F7,P50570,Q9NZ08,P35914,P51572,P61978,Q9NR50,Q8N3U4,Q9HC07,Q05086,P06280,P23786,Q9NR77,P20700,P14174 27 +Corneal dystrophy 0.7661157571096988 1.6829999039364798 0.092375110020094 1.0 0.7179564051008754 5 Q53H12,Q9Y5Z9,P06280 3 +Sensory ataxia 0.7658905903990758 1.6820572695340512 0.0925577352271327 1.0 0.7179564051008754 5 Q9NR77,P54802 2 +Easy fatigability 0.5247898452586574 1.6785929676066162 0.0932313980578209 1.0 0.7192652504392224 21 O95817,P50570,Q96RR1,P61978,Q9BQP7,Q9H553,Q53H12,Q13586,Q9NWM8 9 +Vitiligo 0.7088448409308987 1.6756780252996828 0.0938012763748914 1.0 0.7192652504392224 7 P03886 1 +Pleural effusion 0.7088427411514763 1.6756686189767696 0.0938031198459135 1.0 0.7192652504392224 7 P14174,Q9NZ08,P52732 3 +Thickened ribs 0.8289583462379679 1.6732167718934876 0.0942846297787882 1.0 0.7192652504392224 4 P16278 1 +Punctate cataract 0.8285783066660846 1.671718376849426 0.0945798686511363 1.0 0.7195070146196881 4 Q9H6K4 1 +Positive romberg sign 0.6583962383257852 1.669866405205917 0.0949457984103376 1.0 0.7195070146196881 9 P07196,Q9H6K4,P41440 3 +Zonular cataract 0.6396107010953486 1.66904770439738 0.0951079260578091 1.0 0.7195070146196881 10 Q9H6K4 1 +Rapidly progressive 0.6224565483073033 1.6688853133489516 0.0951401107631773 1.0 0.7195070146196881 11 Q14108 1 +Hepatic failure 0.4718734877871168 1.665140970407628 0.0958846344816961 1.0 0.7239289903368059 46 O43772,P00846,Q9Y619,Q6NUQ1,O95453,Q6PGP7,O75381,P22830,Q13510,P35670,P23786,O75648,O15118,P03886,Q10713,P50416 16 +Chronic diarrhea 0.5356877037286463 1.6601063540893148 0.0968930588788195 1.0 0.7303253855591553 17 Q04656,Q9BT22,P02786,Q13277,Q13510,Q08J23,Q96A33,Q96J02 8 +Hemiplegia hemiparesis 0.4605186615160537 1.6579609836476084 0.0973253417389292 1.0 0.7312434185108437 33 Q9NZ08,P00403,P35914,P57740,Q9BVA1,P03886,O43791,P50416,Q8IY17 9 +Prominent superficial blood vessels 0.6203791654586222 1.657899762717118 0.0973377000799202 1.0 0.7312434185108437 11 Q9Y487 1 +Erythema 0.5538018934417104 1.6527470713820211 0.0983823501125746 1.0 0.7342882544228372 15 P98194,P22830,P03886,P51648,Q06136 5 +Vertebral compression fracture 0.5531046214706082 1.648424231240253 0.0992656470259509 1.0 0.7342882544228372 15 Q96HY6,Q14108,O75718 3 +Pathologic fracture 0.5841050489242312 1.6480326395223102 0.0993459735542994 1.0 0.7342882544228372 13 Q14108 1 +Undetectable electroretinogram 0.822555450492525 1.647951926555142 0.0993625365099 1.0 0.7342882544228372 4 P50897 1 +Central apnea 0.671321770943721 1.6468205353094123 0.0995949391504853 1.0 0.7342882544228372 8 Q10713,Q8N3U4,P07602 3 +Recurrent fever 0.583739776320471 1.645928652730584 0.0997784490359825 1.0 0.7342882544228372 13 Q13510,P51572,Q9NR77,P28070,Q13586 5 +Axonal degeneration 0.7202475360491263 1.6456212161972523 0.0998417683091927 1.0 0.7342882544228372 6 Q6DKK2,Q9BQT8 2 +Small epiphyses 0.8218246764159327 1.6450657469864978 0.0999562533612157 1.0 0.7342882544228372 4 O95831 1 +Prominent sternum 0.9531653746769998 1.6423307723402445 0.1005214731363395 1.0 0.7342882544228372 2 P16278 1 +Abnormal brain lactate level by mrs 0.6524665023466271 1.640877712917395 0.1008228022629149 1.0 0.7342882544228372 9 O43819,P03886 2 +Premature skin wrinkling 0.5265524775289795 1.6398440212265506 0.1010376025447676 1.0 0.7346714920189368 19 Q9Y487,Q9BZK7,O95453,O75844 4 +Abnormal placenta morphology 0.6693688248796716 1.6376077974531795 0.1015035354308013 1.0 0.7348893588816084 8 O75844,Q6PGP7,P16278 3 +Abnormal activity of mitochondrial respiratory chain 0.4740386565253765 1.6346963965325303 0.1021127082834534 1.0 0.7348893588816084 61 Q9NPL8,Q70HW3,P03886,Q9Y584,Q9HA77,Q7KZN9,O43676,Q9Y2R0,Q9UBX3,P13073,P20674,Q86Y39,O96000,Q96CU9,O75648,Q8TB37,Q9UMS0,Q9Y375,Q9P0J0,O75380 20 +Spondyloepimetaphyseal dysplasia 0.6996469062628573 1.6343981113577828 0.1021752845627932 1.0 0.7348893588816084 7 Q9NR45,Q96HY6,O95831 3 +Hypersplenism 0.6991615634498125 1.6322157311349812 0.102634047974508 1.0 0.7348893588816084 7 Q14108 1 +Macular degeneration 0.5972650760362872 1.6315155417031322 0.1027815831859637 1.0 0.7348893588816084 12 P50897,P51648,Q13510 3 +Focal t2 hyperintense basal ganglia lesion 0.5085547823501149 1.623416621256739 0.1045003739587597 1.0 0.7391101183986826 23 Q9P0J0,P00846,P03886 3 +Abnormal pulmonary interstitial morphology 0.4564458711064363 1.6227641902354697 0.1046398235053718 1.0 0.7391101183986826 33 Q9NSD9,Q14108,O95453,P09601,Q13510,Q13432,Q8IZA0,O00203,P14174 9 +Increased serum pyruvate 0.459351426980866 1.6224680129856337 0.1047031766939887 1.0 0.7391101183986826 36 O43676,O96000,P22695,Q9BWD1,Q96RR1,Q96CU9,Q9NPL8,O95831,Q70HW3,Q8TB37,P03886,Q9Y375,O75380,Q86Y39 14 +Episodic respiratory distress 0.9752965832605344 1.619887542954165 0.1052564362488897 1.0 0.7403907705084943 3 P00846 1 +Avascular necrosis 0.5157180193468498 1.6154565738743365 0.1062118572849579 1.0 0.7459530441873792 21 O75844,Q9Y619,Q14108,Q9NZ08 4 +Unexplained fevers 0.7129336721550286 1.6136033162201882 0.1066134970858239 1.0 0.7476147705863503 6 Q9HC07,P07602 2 +Reduced forced vital capacity 0.8131079776612062 1.6105987482677682 0.1072672068322093 1.0 0.7498772329473895 4 O95453,Q9BQT8 2 +Abnormal macular morphology 0.5107243556141428 1.608223036320488 0.1077863396440992 1.0 0.7509050498872234 22 P50897,Q8NHS3,Q13510,Q8WWY3,P51648 5 +Spastic paraparesis 0.5183456397224494 1.60758707292293 0.1079256452819101 1.0 0.7509050498872234 20 Q6DKK2,Q9Y619,Q5XKP0,Q9H6K4 4 +Decreased muscle mass 0.5463928899236745 1.606728438547417 0.1081139523293768 1.0 0.7509050498872234 15 Q9Y487,Q8NCH0 2 +Abnormal ldl cholesterol concentration 0.5611320943205604 1.601279299595541 0.1093150717746347 1.0 0.7522343278690913 14 P37268,P50402,Q15800,Q8N511,Q9UJS0 5 +Diffuse white matter abnormalities 0.7097251099424238 1.599530957399261 0.1097026756429202 1.0 0.7529592737309526 6 O75306,O43819,P16278 3 +Disproportionate short trunk short stature 0.7450168299045294 1.5943800215983506 0.1108509443668048 1.0 0.7534454654409899 5 P16278 1 +Nodular goiter 0.940891472868214 1.5934582437586604 0.1110574285553904 1.0 0.7534454654409899 2 Q9UNW1 1 +Occipital meningocele 0.7445783955109503 1.592532490434372 0.1112651087546912 1.0 0.7534454654409899 5 Q10713,P21964 2 +Unsteady gait 0.463711732695686 1.5924836111302512 0.1112760826772287 1.0 0.7534454654409899 46 Q10713,Q8N3U4,Q96F07,P07196,O75503,Q8NC96,O75787,Q9NR77,O95831,P49366,Q9H6K4,Q9NR50 12 +Dyschromatopsia 0.690090284163831 1.5913507584450597 0.1115306595382814 1.0 0.7534454654409899 7 Q9H061 1 +Neuronal loss in central nervous system 0.6422497471450485 1.590753290010837 0.1116651087945297 1.0 0.7534454654409899 9 O15118,P07602 2 +Abnormal subcutaneous fat tissue distribution 0.8071821749467176 1.5871261436673625 0.1124840778158398 1.0 0.7534454654409899 4 Q9Y487 1 +Abnormal pyramidal sign 0.4191717939483878 1.585992352521988 0.1127410443597107 1.0 0.7534454654409899 123 P00846,Q99720,O43681,Q9BRK0,P07196,P07602,O95831,O00400,Q9H6K4,Q9Y619,Q9NZ08,P51572,P51648,Q6DKK2,O75298,O75787,P49902,Q9NR77,P20700,Q9P0J0,Q9UEY8,Q8TB37,O14773,P41440,Q8IY17 25 +Ventricular arrhythmia 0.4531600494890299 1.5854390372290532 0.1128666176435608 1.0 0.7534454654409899 34 O43772,P00846,P04899,Q96RR1,O75306,P50402,P00403,P42892,P23786,P50336,P03886,Q03001,Q8NFF5 13 +Abnormal heart rate variability 0.8064116735285535 1.584071769140773 0.1131773878810531 1.0 0.7534454654409899 4 Q8N3U4,P07602 2 +Angina pectoris 0.7053330901862384 1.5802427841610918 0.1140512772349802 1.0 0.7534454654409899 6 O75844,P06280 2 +Hypoventilation 0.6057144957074972 1.580039055875035 0.11409792258113 1.0 0.7534454654409899 11 O43819,O75380,P61978 3 +Macular purpura 0.5256413353108527 1.5784412127600147 0.1144642835316545 1.0 0.7539862952498886 16 Q8NCH0,Q16625,P38435 3 +Focal t2 hyperintense brainstem lesion 0.5132026997495904 1.572192077887614 0.1159060121533943 1.0 0.7574893005529263 20 O43676,O96000,Q96CU9,Q9NPL8,Q8TB37,P03886,Q9Y375,O75380,Q86Y39 9 +Ovoid vertebral bodies 0.7030091292735365 1.5700251520469513 0.1164092598932731 1.0 0.7587538810309743 6 P54802,P15586,P16278 3 +Abnormality of the optic nerve 0.3657555677092282 1.5686336974771662 0.1167333158723211 1.0 0.7597728748586421 242 P00846,O43681,Q96F07,P52732,P07196,P07602,P00403,Q9NPL8,O95831,Q8WWY3,P03886,P04114,O43505,Q7KZN9,O43676,P50897,Q9H061,P37268,Q8NHS3,Q92766,Q9NVI7,Q9H6K4,O60762,Q5XKP0,P21964,P78318,P16278,Q13277,O75381,Q9NZ08,P61978,P51572,Q96PU5,Q5KU26,O75380,O43791,Q9NR50,Q9UHX1,Q86Y39,O96000,Q10713,Q8N3U4,P38435,Q9BUK6,Q9UNW1,Q96RR1,O95202,Q96CU9,P06280,Q8NC96,O43819,O75648,Q96TA2,Q9Y375,Q9P0J0,Q8TB37,P49902,P41440,Q8IY17 59 +Retinal arteriolar tortuosity 0.6195810228206236 1.566922350856883 0.1171328426118922 1.0 0.7601887923092722 10 P21964,P00846 2 +Abnormality of visual evoked potentials 0.514917822963054 1.5610805388591036 0.1185047492324631 1.0 0.762537661964571 19 O43681,O75503 2 +Dysarthria 0.3592786958614084 1.5573148722410546 0.1193957461176127 1.0 0.7671811771812562 150 P00846,O43681,Q14108,P07602,Q7KZN9,O15118,Q9H6K4,Q5XKP0,O75503,P35914,P51648,Q9NR50,Q6DKK2,O14653,Q9P0J0,O43819,Q08J23,Q10713,O14773,P41440 20 +Redundant neck skin 0.6989490675508407 1.5521555728613698 0.1206250034647165 1.0 0.7696215009791066 6 Q9Y487 1 +Abnormality of the wrist 0.4540919552983263 1.5510665273807216 0.1208857417529609 1.0 0.7702002955568398 31 O75844,P16435,Q9BV10,P16278,Q9NR45,Q13510,O95831,Q9H6K4,Q9NUQ7 9 +Abnormal macrophage morphology 0.73283712003748 1.5429706767870208 0.1228378907835594 1.0 0.7760887660383881 5 O15118,P16278 2 +Recurrent sinopulmonary infections 0.6788562831494814 1.540550981001208 0.1234261059789139 1.0 0.7781880471786905 7 Q9NVR5,Q9Y487 2 +Intestinal pseudo obstruction 0.6139509032440965 1.5380524971645482 0.1240357794027984 1.0 0.7781880471786905 10 P03886,P61978,P00403 3 +Abnormality of hepatobiliary system physiology 0.4627276474241537 1.5379187517706765 0.1240684817450779 1.0 0.7781880471786905 76 P00846,Q6NUQ1,O75306,P35670,P03886,Q8N511,Q9BT22,Q13510,O15118,Q96A33,Q5XKP0,O43772,Q9NSD9,Q9Y619,P22695,O95453,Q6PGP7,O75381,Q16625,P35914,P50416,P22830,P83436,O75787,P23786,O43819,O75648,Q10713 28 +Optic nerve hypoplasia 0.5185475561668476 1.5322914412301711 0.1254505322024712 1.0 0.7802681022415635 16 Q8N3U4,P37268,P07196,P61978,Q9NVI7,O43791,Q9UHX1 7 +Vascular tortuosity 0.9507372571594356 1.5306178543657285 0.1258638664411946 1.0 0.7802681022415635 3 P00846 1 +Hypergonadotropic hypogonadism 0.5491188816058545 1.5290368770380494 0.1262553021949373 1.0 0.7802681022415635 14 P48449,Q9BQP7,Q16740,Q9BXW9 4 +Abnormal visual fixation 0.6756659891910516 1.526087345646624 0.1269881131149857 1.0 0.7815980331669635 7 Q5KU26,Q13510 2 +Vascular skin abnormality 0.4339654583297666 1.5241932225464945 0.1274604505660901 1.0 0.7823791884341305 110 P00846,Q14108,P00403,Q9BZK7,Q8IZA0,Q8NCH0,P03886,Q9Y487,Q13586,Q9NWM8,P21964,P16278,P98194,Q16625,P51648,O75844,P38435,P22830,P06280,Q13126,Q08J23,Q06136 22 +Morphological abnormality of the pyramidal tract 0.494530954555731 1.5218960056360311 0.1280351401951807 1.0 0.7839537880946066 23 P00846,Q9Y619,O75298,O95831,O00400 5 +High frequency sensorineural hearing impairment 0.7899123567257371 1.5185448139844255 0.1288771111280513 1.0 0.7877803477728904 4 O75844,Q13510 2 +Abnormality of the cerebrospinal fluid 0.3688390246938504 1.516183567783568 0.1294729419171749 1.0 0.7877803477728904 145 P00846,O43681,O75306,P07602,P00403,Q9NPL8,O95831,P03886,O43505,Q7KZN9,O43676,Q92766,Q15392,Q03252,P13073,Q9BXW9,P21964,Q16625,O75380,Q9NVR5,Q9P0J0,Q86Y39,O96000,P16435,Q8N3U4,Q9Y375,O95202,Q96CU9,P23786,Q9NR77,O43819,Q08J23,P20700,Q10713,Q8TB37 35 +Hypoplastic vertebral bodies 0.690703163879646 1.515790899908595 0.1295722338335676 1.0 0.7877803477728904 6 P16278 1 +Insulin resistant diabetes mellitus 0.6430850539839209 1.512902547079294 0.1303044148406145 1.0 0.7877803477728904 8 O75844,P31751 2 +Generalized limb muscle atrophy 0.6430421484649351 1.5126979381846648 0.1303564035562687 1.0 0.7877803477728904 8 Q8IY17 1 +Cessation of head growth 0.788297346479367 1.5121191106476854 0.130503564002508 1.0 0.7877803477728904 4 Q9NR50 1 +Dysostosis multiplex 0.642294824422712 1.5091335635900869 0.1312646538654247 1.0 0.7877803477728904 8 P10619,P54802,P16278 3 +Intracellular accumulation of autofluorescent lipopigment storage material 0.9189276485788048 1.5059211704511457 0.1320874111797765 1.0 0.7877803477728904 2 O75503 1 +Abnormality of the pulmonary veins 0.6396927391714959 1.496715294237604 0.1344673549391808 1.0 0.7923668584100829 8 Q15392,O75718 2 +Incoordination 0.4594969963287739 1.493907868130343 0.1351997016550168 1.0 0.7923668584100829 68 P00846,Q9UBB4,O43681,Q9Y619,Q96RR1,P07602,Q13510,P35670,O75503,Q05086,O75787,O43819,Q9NR77,Q10713,Q6DKK2,Q13586,O14773 17 +Subcutaneous hemorrhage 0.4468762813295581 1.4892294283306666 0.1364269639673432 1.0 0.7923668584100829 39 P21964,Q14108,P38435,Q92766,Q16625,Q13126,Q9BZK7,Q8NCH0,Q13586,Q9NWM8 10 +Fatigable weakness of bulbar muscles 0.5716053650462639 1.4885466595327803 0.136606786630377 1.0 0.7923668584100829 12 Q92804,P35637,Q15165 3 +Extrapyramidal muscular rigidity 0.6844670895039888 1.4882282500261812 0.1366907095165666 1.0 0.7923668584100829 6 Q9H6K4 1 +Gingival bleeding 0.5565084403414797 1.4879919263243568 0.1367530228433537 1.0 0.7923668584100829 13 Q14108 1 +Muscle fiber atrophy 0.5008899255924065 1.487035250381916 0.1370055010846209 1.0 0.7923668584100829 20 Q99720,P50402,P61978,P23786,Q13586 5 +Generalized onset motor seizure 0.4560378351315362 1.4858870168791114 0.1373090082801626 1.0 0.7923668584100829 54 P00846,P16278,Q8NHS3,P07602,P03886,Q9HA77 6 +Atrophy degeneration involving the corticospinal tracts 0.5550838216448828 1.4796735027858032 0.1389604002304432 1.0 0.7923668584100829 13 P00846,O75298 2 +Mixed demyelinating and axonal polyneuropathy 0.7177873996649351 1.4792202766400775 0.1390814520030225 1.0 0.7923668584100829 5 P07196,P03886 2 +Abnormality of the lymph nodes 0.439797659473837 1.477842102242817 0.1394500462745507 1.0 0.7923668584100829 33 Q9UNW1,Q9NZ08,Q13510,Q9BZK7,P33991,P14174,Q13586 7 +Increased connective tissue 0.635466946826693 1.476523316462777 0.139803460595798 1.0 0.7923668584100829 8 O95831,O75431,P31751 3 +Orthostatic hypotension due to autonomic dysfunction 0.6189031450065516 1.475416001550851 0.1401007359583619 1.0 0.7923668584100829 9 O43681,P07602,P20700 3 +Urinary bladder sphincter dysfunction 0.6187553415536029 1.474682500350897 0.1402979230064329 1.0 0.7923668584100829 9 Q9NR77,O75298 2 +Angiokeratoma 0.7780984002764282 1.4714970490731756 0.1411567449750412 1.0 0.7923668584100829 4 P16278 1 +Retinal coloboma 0.5996715458745917 1.4645308116875086 0.1430489707258784 1.0 0.7980232263816625 10 Q9UHX1 1 +Chorea 0.4539291166875766 1.4637323068177786 0.1432671046342017 1.0 0.7980232263816625 80 P00846,Q99720,O43681,Q9UBB6,Q9BWD1,P07602,Q5XKP0,O43819,Q08J23,Q71SY5,Q9H6K4,P03886,Q9P0J0,Q9HA77 14 +Supraventricular arrhythmia 0.5227922730903447 1.458944686330889 0.1445803325341694 1.0 0.7985319503244092 15 P00846,Q8NFF5,P50402,Q96RR1 4 +Abnormality of lysosomal metabolism 0.7748206017064938 1.458426942870391 0.1447228987232538 1.0 0.7985319503244092 4 P07602,Q13510 2 +Chronic fatigue 0.6313891056260175 1.4570100526961391 0.1451136053108517 1.0 0.7997136643043288 8 Q13423 1 +Gait ataxia 0.4555279005056175 1.4557147804513264 0.1454714822425908 1.0 0.8007118038383192 67 P00846,Q9UBB4,O43681,Q14108,Q96RR1,P07196,P07602,Q9NR77,Q9NVI7,O15118,P03886,P20700,Q10713,Q03252,O14773,P41440,Q8IY17 17 +Functional motor deficit 0.35762786487508 1.454810926764672 0.1457216123457436 1.0 0.8011151746677412 148 P00846,Q99720,O43681,Q96F07,P07196,P07602,P00403,Q71SY5,P03886,Q13586,Q8NFF5,Q9NWM8,Q9Y2R0,Q13510,Q53H12,Q9NSD9,O14653,Q9BUK6,O75298,Q9H2D1,Q8NC96,P23786,Q9NR77,O43819,O75787,P20700,Q8TB37,O14773 28 +Cutaneous photosensitivity 0.4925563209337423 1.4527367420525192 0.1462968614154975 1.0 0.8013750127546032 21 P37268,P22830,Q08J23,Q14108 4 +Aspiration pneumonia 0.4757655269498284 1.448835627323227 0.1473834916845222 1.0 0.8063372189986543 25 P78318,Q13510,P16278,P20700 4 +Mitral valve calcification 0.7706335430843597 1.4417216853865795 0.149380903514956 1.0 0.8110055482980908 4 O75844 1 +Cardiac valve calcification 0.7706335430843597 1.4417216853865795 0.149380903514956 1.0 0.8110055482980908 4 O75844 1 +Generalized hyperpigmentation 0.6120297976360284 1.4412644704220383 0.1495099807791298 1.0 0.8110055482980908 9 Q13423,P51648 2 +Small basal ganglia 0.6264644518088891 1.4334088726137388 0.1517410242691386 1.0 0.8136053251599735 8 P00846 1 +Foam cells 0.6720780530312401 1.4333241212186332 0.1517652317351385 1.0 0.8136053251599735 6 O15118,P16278 2 +Paraparesis 0.4636366286338976 1.4319593553719407 0.1521554536953198 1.0 0.8139041873329864 27 Q9Y619,Q13510,Q9H6K4,Q6DKK2,Q5XKP0 5 +Abnormal larynx physiology 0.5469143336767708 1.4318724803454004 0.1521803193534303 1.0 0.8139041873329864 13 Q15165,Q13510 2 +Congenital hip dislocation 0.4732848997978383 1.4300406643419128 0.1527053483765919 1.0 0.8157490897947656 25 Q9Y487 1 +Distal upper limb amyotrophy 0.577242982808533 1.427420508817737 0.1534587228072361 1.0 0.8162310812234836 11 Q9NR77,Q9BQT8 2 +Thick hair 0.6539482067789562 1.427220631917709 0.1535163093162048 1.0 0.8162310812234836 7 Q9Y487 1 +Abnormal circulating lipid concentration 0.4508016249761873 1.4253375625869251 0.1540596470563731 1.0 0.8181596731129778 78 O95470,P07602,P31751,P57740,Q9NZJ7,P04114,O75880,Q16836,Q9UJS0,Q8N511,P37268,Q15392,P28070,Q9NVI7,Q03252,O43772,P61916,O75381,P50402,P35914,Q15800,O75431,P50416,O75844,Q9BV10,P22830,P06280,P23786,O75648 29 +Episodic tachypnea 0.6685099490483373 1.417477765719828 0.1563432904843029 1.0 0.824537518394655 6 P22695 1 +Blindness 0.4503049033592451 1.4174455630841754 0.1563526994041961 1.0 0.824537518394655 77 P00846,P52732,O75306,P07602,Q9NPL8,Q8WWY3,P03886,O43505,O43676,P50897,P06865,Q8NHS3,Q9H6K4,P16278,Q9NZ08,O75380,Q9NR50,Q86Y39,O96000,Q96CU9,Q9Y375,Q8TB37 22 +Pediatric onset 0.3474786886680822 1.4150835965935298 0.1570439870493614 1.0 0.8262593046847935 218 Q6NUQ1,O75306,P07196,Q9NRW7,P07602,Q9NPL8,O00584,P57740,O95831,Q70HW3,O00400,Q5BJH7,O75027,P06865,Q8NHS3,Q13510,Q9NVI7,P49366,O15118,O60762,Q53H12,Q5XKP0,Q03252,Q9NSD9,Q5JRA6,P16278,P50570,O95453,P50402,O75746,Q9NR50,P20674,Q9NUQ7,O75431,Q10713,Q9UBB6,Q9Y375,Q9BUF5,P22830,Q96CU9,P06280,O75787,P23786,Q9NR77,P54802,O75648,Q96TA2,P20700,Q9P0J0,Q9UEY8,O14773,P41440,Q8IY17 53 +Male reproductive system neoplasm 0.5297863984308949 1.4119109141999675 0.1579761936926798 1.0 0.8264647495827846 14 Q13423 1 +Abnormal intraocular pressure 0.7018797324374889 1.4115983114091466 0.1580682698888704 1.0 0.8264647495827846 5 Q8NCH0 1 +Recurrent aspiration pneumonia 0.6670803099929898 1.4111245977240114 0.1582078782634428 1.0 0.8264647495827846 6 Q13510 1 +Chronic pulmonary obstruction 0.6503240309776335 1.4106579786951787 0.1583454870368126 1.0 0.8264647495827846 7 P21964,P09601,P06280 3 +Urinary glycosaminoglycan excretion 0.6658045426850301 1.4054533439475894 0.1598865137789675 1.0 0.8287024112342369 6 P16278 1 +Abnormal circulating copper concentration 0.6485133790246786 1.4023768736824986 0.1608027355237649 1.0 0.8303205767792331 7 Q9Y487 1 +Fatigable weakness of swallowing muscles 0.5725021723038499 1.4018393805599034 0.1609632157964924 1.0 0.8303205767792331 11 Q92804,P35637,Q15165 3 +Impaired social interactions 0.4454241814951712 1.4011647885697225 0.1611648011068476 1.0 0.8303205767792331 51 O43676,O96000,Q96RR1,O75306,Q9UHX1,Q96CU9,Q9NPL8,Q5KU26,Q8TB37,P03886,O75746,Q9Y375,Q9P0J0,O75380,Q5XKP0,Q86Y39 16 +Abnormality of the mitochondrion 0.4362013128582056 1.3991449889893213 0.161769509001195 1.0 0.8303205767792331 98 P00846,O75306,P00403,Q9NPL8,Q9BQP7,Q70HW3,P03886,Q9Y584,O75880,Q9HA77,Q7KZN9,O43676,Q9Y2R0,Q9UBX3,P13073,O43772,Q4J6C6,P35914,O75380,P20674,Q86Y39,O96000,Q96RR1,Q96CU9,P23786,Q9UMS0,O75648,Q9Y375,Q9P0J0,Q8TB37 30 +Joint swelling 0.6987499242062669 1.3982689213044186 0.1620323269173975 1.0 0.8303205767792331 5 P14174,Q13510 2 +Abnormality of circulating leptin level 0.7590700531346021 1.395537215136055 0.1628539005088027 1.0 0.831711577570323 4 O75844 1 +Abnormal circulating carbohydrate concentration 0.4377398583501806 1.3927689279718436 0.1636896773247445 1.0 0.834151934491504 41 O43676,O96000,P22695,Q9BWD1,Q96RR1,Q96CU9,Q9NPL8,O95831,Q70HW3,Q8TB37,P03886,Q9Y375,O75380,Q86Y39,Q9UJS0 15 +Paroxysmal involuntary eye movements 0.4806214531472074 1.392734752645785 0.163700015400209 1.0 0.834151934491504 22 O43676,O96000,Q96CU9,Q9NPL8,Q8TB37,P03886,Q9Y375,O75380,Q86Y39 9 +Abnormal circulating ceruloplasmin concentration 0.7581948374895404 1.3920390107677858 0.1639105851136881 1.0 0.8342864613089971 4 Q8N511 1 +Cystic hygroma 0.6625466007040907 1.3909627604489747 0.1642367195530978 1.0 0.8350082374585108 6 P62070,Q99567,P61978 3 +Recurrent pancreatitis 0.9122185540413624 1.3902668546031371 0.1644478588872469 1.0 0.835144395469987 3 P03886 1 +Pulmonary infiltrates 0.6618063881689954 1.387668928376215 0.1652378816886659 1.0 0.8366394468301388 6 Q13510 1 +Constitutional symptom 0.3529669529889975 1.3852514112712604 0.1659756053216874 1.0 0.8366394468301388 236 P00846,Q99720,O43681,Q14108,Q96HY6,P52732,Q9BRK0,P07196,P07602,P35670,P57740,Q9BZK7,Q70HW3,P50336,P04114,Q9HA77,Q13586,O15269,Q9UJS0,P04899,Q9UP83,Q92766,Q9UGP8,Q13510,Q92804,P28070,Q9H6K4,Q53H12,Q03252,Q13423,P21964,Q8N1F7,P50570,Q4J6C6,Q9NZ08,P50402,P35914,Q15800,Q9NUQ7,P42892,P50416,O75844,Q15165,Q9UBB4,Q9BUK6,Q9UNW1,O75298,Q96RR1,P06280,P23786,Q9NR77,P20700,P14174 53 +Hypoplasia of the odontoid process 0.7563365745528123 1.3846105313900894 0.1661715894762476 1.0 0.8366394468301388 4 P16278 1 +Abnormal renal cortex morphology 0.4411279128598268 1.3833085913652745 0.1665702648300409 1.0 0.8371486761730892 47 P00846,Q8N1F7,Q14108,O95470,Q9NZ08,P00403,P06280,P03886,Q03252,O75431 10 +Postural instability 0.4936849261766456 1.3823139251324392 0.1668753321378144 1.0 0.8371486761730892 17 Q9NR77,O75503 2 +Reduced visual acuity 0.4175648760048994 1.3778342923724614 0.1682544557044154 1.0 0.8422018611502784 113 P00846,O43681,P52732,O75306,P07602,O15294,Q9NPL8,Q8WWY3,Q71SY5,P03886,O43505,O43676,P50897,Q9H061,P06865,Q8NHS3,Q9H6K4,P16278,Q13277,Q9NZ08,O00203,O75380,Q9NR50,Q9UHX1,Q86Y39,O96000,Q96CU9,Q96TA2,Q9Y375,Q10713,Q8TB37 31 +Microcytic anemia 0.5826808599802878 1.3765322363194572 0.1686569140942413 1.0 0.8432845704712066 10 P22830,Q9UBX3,Q9BQT8 3 +Disproportionate short stature 0.4659445048062772 1.374283769419944 0.1693536031080291 1.0 0.8449028877526125 25 Q96HY6,Q9BV10,P16278,Q7LGA3,Q15392,O75718,Q32P28,Q9UHX1 8 +Visual fixation instability 0.7533013990150782 1.3724743387448215 0.1699158220136296 1.0 0.8449162170381365 4 Q5KU26 1 +Constriction of peripheral visual field 0.4840090448048358 1.369401975481482 0.1708736570957063 1.0 0.8468902260870348 20 P00846 1 +Narrow nasal ridge 0.6572050955422454 1.3671816144153652 0.1715683867008388 1.0 0.8494041439943169 6 O75844 1 +Bruising susceptibility 0.438421537132629 1.3644035392584957 0.1724405946082539 1.0 0.8509323459426907 30 Q14108,P38435,Q13126,Q9BZK7,Q8NCH0 5 +Pericarditis 0.7505604716604319 1.3615117988180352 0.1733520074517289 1.0 0.8544990138806662 4 Q9NZ08 1 +Slender long bone 0.5068690601930417 1.3583083057198715 0.174365875881461 1.0 0.8567000192440547 15 Q9Y487,P37268,Q9Y619 3 +Ecchymosis 0.5334933641567328 1.3530020159466978 0.1760549863481526 1.0 0.8592889083901384 13 Q8NCH0,P38435 2 +Short nail 0.7483036849015787 1.3524837391329432 0.1762206171952403 1.0 0.8592889083901384 4 Q9Y487 1 +Irregular vertebral endplates 0.687726599103271 1.3512670365784705 0.1766099072938867 1.0 0.859337142901511 5 Q9NR45 1 +Bile duct proliferation 0.9007884457733046 1.3486008514058303 0.1774652070673956 1.0 0.8601191847929461 3 Q9NSD9 1 +Wormian bones 0.4860361278870812 1.345983505591129 0.1783078361029042 1.0 0.8601191847929461 18 O75844,Q9Y487,O95831,O75718 4 +Variable expressivity 0.4434950493311967 1.344947187809432 0.178642290085337 1.0 0.8601191847929461 75 P52732,O95470,P07196,P07602,P00403,P57740,Q70HW3,P03886,Q9NZJ7,Q13586,Q9H061,Q13510,Q9BVA1,O60762,Q53H12,O95453,Q9BUF5,Q6P4A7,Q9NR77,Q9Y375,Q9UEY8,Q8TB37 22 +Decreased ldl cholesterol concentration 0.686214007885124 1.3448115415531177 0.1786861021328003 1.0 0.8601191847929461 5 P37268,Q15800 2 +Gliosis 0.4295712369381312 1.3434414369798535 0.1791290770054854 1.0 0.8601191847929461 38 Q9NR50,P00846,O43819,Q7KZN9 4 +Osteolytic defects of the distal phalanges of the hand 0.7451012088423461 1.339669944863721 0.1803526729212015 1.0 0.8601191847929461 4 O75844 1 +Abnormality of prothrombin 0.5176120753617732 1.3376625611223447 0.1810064605969246 1.0 0.8601191847929461 14 P38435,Q9BV10,Q6NUQ1,P35914,Q5XKP0,Q9UJS0 6 +Intestinal malrotation 0.4408160684070445 1.3358559491758522 0.1815963615334725 1.0 0.8601191847929461 29 P21964,Q9NSD9,Q92766,O95202,Q15392,Q8NCH0,Q9NVR5 7 +Abnormal pericardium morphology 0.5908697288917171 1.3356373423716152 0.1816678383962457 1.0 0.8601191847929461 9 Q9NZ08,Q14108 2 +Bifid scrotum 0.649780858712368 1.334083260926406 0.1821765710565186 1.0 0.8601191847929461 6 P16435,O60315,Q69YQ0,O60566 4 +Abnormal pharynx morphology 0.4263654007672528 1.3321097544050138 0.1828241254682943 1.0 0.8601191847929461 36 Q03518,P16278,Q13277,Q13510,P54802 5 +Biliary cirrhosis 0.6329971308646971 1.3312521484833624 0.1831060575756908 1.0 0.8601191847929461 7 P14174,P09601 2 +Excessive wrinkling of palmar skin 0.8959924390112177 1.3311228011469765 0.1831486075783477 1.0 0.8601191847929461 3 Q9Y487 1 +Transient ischemic attack 0.6050761797510775 1.3304924822213349 0.1833560616747434 1.0 0.8601191847929461 8 O75844 1 +Low levels of vitamin d 0.6046908322142726 1.3286326633290988 0.1839691903549893 1.0 0.8617856050792977 8 Q9NSD9 1 +Spinal muscular atrophy 0.5283958684157757 1.3229442977843988 0.1858539024560817 1.0 0.865280758608479 13 Q99720 1 +Aplasia hypoplasia involving the vertebral column 0.5273940064860948 1.317030710415904 0.1878283307215036 1.0 0.8657229802128026 13 O95831,Q96HY6,P16278 3 +Prenatal maternal abnormality 0.5139031059005047 1.314976120908569 0.1885179279048869 1.0 0.8657229802128026 14 O43772,P16435,P49366,P50416 4 +Abnormal morphology of the conjunctival vasculature 0.6448814739811993 1.3122153392746874 0.1894474876911809 1.0 0.8657229802128026 6 P10619,P04066,P06280 3 +Aplasia hypoplasia of the optic nerve 0.478366603640409 1.310495023872099 0.1900284265149392 1.0 0.8657229802128026 19 P37268,P07196,P61978,Q9NVI7,O43791,Q9UHX1 6 +Aplasia hypoplasia affecting the fundus 0.478366603640409 1.310495023872099 0.1900284265149392 1.0 0.8657229802128026 19 P37268,P07196,P61978,Q9NVI7,O43791,Q9UHX1 6 +Chronic sinusitis 0.7377901855719982 1.3104077775774043 0.1900579239202304 1.0 0.8657229802128026 4 Q03518 1 +Abnormality of lower limb joint 0.3183309161409513 1.3072807559190864 0.1911173775008816 1.0 0.8657229802128026 167 Q9Y2D4,Q96HY6,Q6NUQ1,P07602,O95831,Q9NZJ7,Q9Y584,Q9Y487,Q9UP83,Q7LGA3,P37268,Q92766,Q13510,Q86XL3,Q9NQT5,O60762,Q96A33,Q03252,Q9BXW9,P21964,Q9Y619,Q5JRA6,P16278,Q9NR45,Q96PU5,O00203,Q9UHX1,O75431,Q9NUQ7,O75844,P16435,Q8N3U4,O75298,O95202,Q05086,O75787,P23786,Q9NR77,O75718,P49902 40 +Unilateral renal agenesis 0.4842979936067723 1.307222665978089 0.1911370997549411 1.0 0.8657229802128026 16 Q86XL3,Q9UHX1 2 +Abnormality of exocrine pancreas physiology 0.480275802106256 1.3067957330465705 0.1912820947261901 1.0 0.8657229802128026 18 P14174,Q9UHX1,P09601 3 +Erlenmeyer flask deformity of the femurs 0.7367869727316559 1.30639167203529 0.1914193964660959 1.0 0.8657229802128026 4 P07602 1 +Flared iliac wing 0.7366588880231344 1.305878907200339 0.1915937406277774 1.0 0.8657229802128026 4 P16278 1 +Amelogenesis imperfecta 0.7363798985912283 1.3047620137141722 0.1919738976444556 1.0 0.8657229802128026 4 Q13586,Q9HC07 2 +Abnormality of glycolipid metabolism 0.6270809175449731 1.3040645097655108 0.1922115882515336 1.0 0.8657229802128026 7 O43681,P07602,P06280 3 +Abnormal circulating proteinogenic amino acid derivative concentration 0.4522178805120245 1.303810585394374 0.1922981725559203 1.0 0.8657229802128026 26 O96000,P00846,P22695,P03886,P20674,Q5XKP0,Q9P0J0 7 +Abnormal lung lobation 0.538675766034958 1.3028156800038453 0.1926376962592726 1.0 0.8657229802128026 12 P21964,Q9UHX1 2 +Tetraplegia tetraparesis 0.4296561911176321 1.2916309001609558 0.1964849977292899 1.0 0.8703967415881867 45 P00846,O43681,P07602,P51572,O95831,Q9UBX3,P20700,Q9HA77,Q13423 9 +Upper limb muscle weakness 0.4550817913229725 1.2914150521170047 0.1965597939613057 1.0 0.8703967415881867 25 P00846,P50570,P07196,P50402,P50336,Q8WXH0,Q969X5 7 +Tongue fasciculations 0.536407080232332 1.2899425319938451 0.1970706119891034 1.0 0.870955972985989 12 O95831,Q13510 2 +Upper airway obstruction 0.7321361665774154 1.2877717437315686 0.1978254310388694 1.0 0.872589291729385 4 O75844,P16435 2 +Psychotic mentation 0.6722426885903796 1.2851297400900403 0.1987469505458077 1.0 0.8729016624540268 5 P03886 1 +Head tremor 0.5086149972288894 1.28258221080595 0.1996384858167128 1.0 0.8729016624540268 14 Q99720,P07196 2 +Impaired visuospatial constructive cognition 0.6223918827562103 1.282492958572486 0.1996697734765264 1.0 0.8729016624540268 7 Q10713,P03886 2 +Prolonged partial thromboplastin time 0.6380431694109361 1.2816631475826947 0.1999608378770849 1.0 0.8729016624540268 6 P38435,Q9BV10,O60762 3 +Varicose veins 0.6713811137307281 1.2814466565841898 0.2000368251704936 1.0 0.8729016624540268 5 P21964 1 +Aplasia hypoplasia involving the femoral head and neck 0.5642824859480476 1.2807005287757562 0.2002988739840794 1.0 0.8729016624540268 10 Q9Y2D4,Q96HY6,Q9NR45,O95831,O75431 5 +Depletion of mitochondrial dna in muscle tissue 0.7302973062450557 1.2804091868830016 0.2004012646693571 1.0 0.8729016624540268 4 Q9UBX3 1 +Brittle hair 0.5209266016393467 1.2788114068094745 0.2009634760773897 1.0 0.8740423773401307 13 O75844,Q9Y487,Q9NVI7 3 +Hypocalcemia 0.4797419022814005 1.277041497785326 0.2015875970067904 1.0 0.8740423773401307 16 P21964,Q9NSD9,Q4J6C6,Q92766,Q96DF8 5 +Increased muscle lipid content 0.5634319840702926 1.2762588567621675 0.2018640290327462 1.0 0.8740423773401307 10 P23786,Q9BUK6 2 +Psoriasiform dermatitis 0.8611111111111027 1.275835238386149 0.202013768007752 1.0 0.8740423773401307 2 Q15800 1 +Xerostomia 0.5200969521199893 1.273903210547142 0.2026977204586353 1.0 0.8761647649595591 13 Q92804,P35637,Q15165 3 +Upper limb postural tremor 0.8794830371567103 1.2710014642347822 0.2037281277180045 1.0 0.8789413510119625 3 Q9NR77,Q9HA77 2 +Oligosacchariduria 0.7271705342683538 1.2678897160136418 0.2048373371500198 1.0 0.8794747192115059 4 P10253,P16278 2 +Extra axial cerebrospinal fluid accumulation 0.8575581395348855 1.261755279050528 0.2070368588157358 1.0 0.8825338561231298 2 P20700 1 +Opisthotonus 0.4546902343992441 1.257265457309928 0.2086575277001299 1.0 0.8825338561231298 24 Q99720,P11117,P07602 3 +Loss of subcutaneous adipose tissue in limbs 0.7243132487314938 1.256449296565998 0.2089531181131092 1.0 0.8825338561231298 4 O75844,O75431 2 +Onion bulb formation 0.6323580944873342 1.2562402204598502 0.2090288883757491 1.0 0.8825338561231298 6 Q9NR77,P07196 2 +Bilateral sensorineural hearing impairment 0.4611934257712353 1.251971207043587 0.2105803558834094 1.0 0.8825338561231298 22 P03886,O43681,P07602 3 +Fatigable weakness of respiratory muscles 0.5292595760390579 1.2493326912347145 0.2115434156824573 1.0 0.8825338561231298 12 Q92804,P35637,Q15165 3 +Underdeveloped supraorbital ridges 0.5287056810035973 1.2461824915227386 0.2126974053629446 1.0 0.8825338561231298 12 P98175,P16435,P52732,Q6PGP7,O75381,O96011,Q08J23,O43791,Q56NI9 9 +Abnormality of the distal phalanges of the toes 0.6298648037027472 1.2450848424356171 0.2131005651741073 1.0 0.8825338561231298 6 O75844,O75431 2 +Abnormal cortical bone morphology 0.5020510574986372 1.2423004373164823 0.2141257340762141 1.0 0.8825338561231298 14 Q86XL3 1 +Abnormal iliac wing morphology 0.5569272282230404 1.2422589972082536 0.214141018410624 1.0 0.8825338561231298 10 O95831,P16278 2 +Cherry red spot of the macula 0.5721563389910101 1.2417087522886714 0.2143440395623015 1.0 0.8825338561231298 9 P06865,P07602,P16278 3 +Abnormal autonomic nervous system physiology 0.4238617045945608 1.241446388530542 0.2144408914758855 1.0 0.8825338561231298 30 P41440,O43681,P42892,P06280 4 +Abnormal femoral neck morphology 0.4167620430162196 1.2375626309802803 0.2158782777765779 1.0 0.8825338561231298 37 O75844,Q9Y619,Q96HY6,P16278,Q9NR45,O95831,O75718,Q96A33,Q9Y487,Q9NUQ7,O75431 11 +Lambdoidal craniosynostosis 0.8510981912144726 1.236185291900192 0.216389696566821 1.0 0.8825338561231298 2 P16435 1 +Dysphagia 0.3817448262829127 1.235792903857453 0.2165355533759132 1.0 0.8825338561231298 129 P00846,Q99720,Q14108,O75306,P07602,P35670,Q9BQP7,P15586,Q8IZA0,P03886,Q9HA77,Q8NFF5,Q13510,O15118,P61916,Q9UHX1,Q8N3U4,Q9UBB4,Q9BUF5,Q96RR1,Q05086,Q9NR77,O43819,P20700,Q9UEY8 25 +Abnormal circulating free fatty acid concentration 0.7187510272121742 1.2341800236415383 0.217135829487385 1.0 0.8825338561231298 4 Q16836,O75431 2 +Hypoglycemic coma 0.570611313353931 1.2339365393894692 0.2172265524952368 1.0 0.8825338561231298 9 Q13423,P31751 2 +Abnormal nephron morphology 0.4281405937290624 1.2319057086118523 0.2179843087165132 1.0 0.8825338561231298 53 P00846,Q14108,Q9NZ08,P06280,P23786,O43819,P03886,O75431 8 +Parkinsonism 0.4282148087189522 1.231585940350472 0.2181037955651128 1.0 0.8825338561231298 29 P61457,Q99720,Q96RR1,P07602,O75787,Q9NZJ7 6 +Abnormal retinal vascular morphology 0.4258035467083689 1.2314097723235746 0.2181696438512332 1.0 0.8825338561231298 49 P00846,P21964,P38435,P16278,O75306,P06865,Q92766,P07602,Q13510,P10619,Q8WWY3,P03886,Q96DF8 13 +Abnormal myocardium morphology 0.3145063257392381 1.2305697121549104 0.2184838390071146 1.0 0.8825338561231298 168 P00846,Q14108,O75306,P00403,Q9NPL8,P57740,Q9BQP7,P15586,P03886,Q8NFF5,Q7KZN9,O43676,Q9BT22,Q9H061,Q9NVI7,Q53H12,Q5XKP0,Q13423,Q9BXW9,O43772,P16278,O75381,Q9NZ08,P50402,P35914,O75380,P50416,Q86Y39,O96000,P42167,Q96RR1,Q96IX5,Q96CU9,P06280,P83436,P23786,O43819,P54802,Q9Y375,Q9P0J0,Q8TB37 41 +Brain imaging abnormality 0.416917312661811 1.2302113783977036 0.2186179600956839 1.0 0.8825338561231298 38 Q9BT22,Q9BV10,O75306,P07602,P00403,Q05086,O43819,Q9BZK7,P03886 9 +Abnormal atrioventricular conduction 0.5545763747068165 1.2299593504385558 0.2187123273072009 1.0 0.8825338561231298 10 O43772,P06280 2 +Incomplete penetrance 0.4105082974490658 1.2293297509821068 0.21894819702964 1.0 0.8825338561231298 32 O14979,P00846,Q9UBB4,P52732,O95453,Q92733,Q8WWY3,P03886 8 +Caesarian section 0.7175345463099386 1.2293101379628522 0.2189555476776785 1.0 0.8825338561231298 4 P33991 1 +Cardiovascular calcification 0.5543695694110208 1.2288770648581395 0.2191179017623079 1.0 0.8825338561231298 10 O75844,O75431 2 +Respiratory arrest 0.5832887364924615 1.2250878322985683 0.220542129164684 1.0 0.8825338561231298 8 O43772,P23786 2 +Abnormality of skull ossification 0.5249022865031531 1.2245399961473713 0.2207485878537518 1.0 0.8825338561231298 12 O75844,P54802,O75718 3 +Limited wrist movement 0.7153399862127792 1.22052539223338 0.2222657697164163 1.0 0.8825338561231298 4 Q9H6K4 1 +Aplasia hypoplasia involving the skeletal musculature 0.5822712310194834 1.2201545650453232 0.2224062869263816 1.0 0.8825338561231298 8 O43505,Q9NR77,Q9Y487 3 +Abnormal circulating sex hormone concentration 0.4652479563848087 1.21960498330552 0.2226146564037965 1.0 0.8825338561231298 19 Q9NR50,P16435,Q13423 3 +Abnormal abdomen morphology 0.337599324628114 1.2191287759338227 0.2227953195583039 1.0 0.8825338561231298 221 P00846,Q9UJW0,Q14108,Q96HY6,Q6NUQ1,O75306,Q9NRW7,P07602,P31751,P35670,Q9NPL8,P15586,P03886,O75880,Q9UJS0,O43676,Q9UP83,Q9BT22,Q92766,Q9UGP8,Q15392,Q13510,P28070,Q9NVI7,O15118,P33991,O60762,Q96A33,O43772,P21964,Q9NSD9,Q9Y619,P61916,P16278,O95453,Q6PGP7,O75381,Q9NZ08,P09601,Q16625,P35914,O00203,O75380,P20674,O75431,P50416,Q86Y39,O96000,Q96CU9,Q9HC07,P83436,O75787,P23786,P10619,P54802,O75648,Q9Y375,Q10713,P14174,Q8TB37 60 +Abnormal liver morphology 0.3446671201408519 1.2183595495239672 0.2230873696514832 1.0 0.8825338561231298 239 P00846,Q9UJW0,Q14108,Q96HY6,Q6NUQ1,O75306,Q9NRW7,P07602,P31751,P35670,Q9NPL8,P15586,P03886,Q9NZJ7,P04114,O75880,Q9HA77,Q7KZN9,Q8N511,O43676,Q9UJS0,Q9UP83,Q9BT22,Q9UGP8,Q13510,P28070,Q9NVI7,O15118,P33991,O60762,Q96A33,Q03252,Q5XKP0,O43772,Q9NSD9,Q9Y619,P61916,P16278,O95453,Q6PGP7,O75381,P09601,Q16625,P35914,O00203,O75380,P20674,O75431,P50416,Q86Y39,O96000,P22830,Q9HC07,Q96CU9,P83436,O75787,P23786,P10619,P54802,O75648,Q9Y375,Q10713,P14174,Q8TB37,Q8IY17 65 +Myositis 0.5818977327102381 1.2183435021900413 0.2230934652146226 1.0 0.8825338561231298 8 Q9NZ08 1 +Increased adipose tissue 0.7140666035354316 1.2154285260526037 0.2242026936446524 1.0 0.8825338561231298 4 P31751 1 +Telangiectasia 0.4100324495856079 1.2150799498277782 0.2243355999152239 1.0 0.8825338561231298 33 P00846,P03886,P06280 3 +Psychosis 0.4143240510999931 1.209416295491485 0.2265029512647911 1.0 0.8825338561231298 31 P61916,P00403,P50336,O15118,P03886,Q6DKK2,Q9UJS0 7 +Atrophy degeneration involving the spinal cord 0.5800297375175367 1.209284220089596 0.2265536711278719 1.0 0.8825338561231298 8 P07196,Q8IY17,P20700 3 +Limb dystonia 0.4654835471234612 1.2057986379798256 0.227895140810554 1.0 0.8825338561231298 18 Q99720 1 +Status epilepticus with prominent motor symptoms 0.8430232558139417 1.2042839608725031 0.2284798437887194 1.0 0.8825338561231298 2 Q13510 1 +Pigmentary retinopathy 0.4214615134902907 1.2037178132581272 0.2286986648736906 1.0 0.8825338561231298 47 P00846,Q8NHS3,P03886,Q9P0J0,Q8IY17 5 +Impaired smooth pursuit 0.467879894901627 1.198260248096952 0.2308157170105835 1.0 0.8825338561231298 16 Q10713,P41440,P46977 3 +Widened cerebral subarachnoid space 0.7097121467452567 1.1980023001011344 0.230916121545184 1.0 0.8825338561231298 4 P03886,P00403 2 +Ketotic hypoglycemia 0.859138352720796 1.197073100793908 0.2312780634251343 1.0 0.8825338561231298 3 Q13423 1 +Delayed menarche 0.6516061688763459 1.1968682662516268 0.2313579047943963 1.0 0.8825338561231298 5 O75844 1 +Sea blue histiocytosis 0.8590501886956121 1.1967532673173404 0.2314027381991366 1.0 0.8825338561231298 3 O15118 1 +Long toe 0.5630323891405057 1.1957804422376843 0.2317822500265802 1.0 0.8825338561231298 9 P23786,Q9UHX1,O60762 3 +Proximal tubulopathy 0.4425296143566408 1.195205648406597 0.2320066922381207 1.0 0.8825338561231298 25 O43676,O96000,Q96CU9,P00403,Q9NPL8,O75380,P03886,Q9Y375,Q8TB37,Q86Y39 10 +Progressive sensorineural hearing impairment 0.5628919846587122 1.1950731405307145 0.2320584550330111 1.0 0.8825338561231298 9 P03886 1 +Cytochrome c oxidase negative muscle fibers 0.576409729166526 1.1917213659003243 0.233370517484907 1.0 0.8825338561231298 8 Q9Y2R0,Q96RR1 2 +Increased csf lactate 0.42521397004031 1.1912566088413152 0.2335528624786806 1.0 0.8825338561231298 56 O43676,P00846,O96000,Q96CU9,P00403,Q9NPL8,O43819,O95831,Q8TB37,P03886,Q9Y375,Q9P0J0,O75380,Q86Y39,Q7KZN9,P13073 16 +Abnormal systemic blood pressure 0.4256517920059792 1.1899812587877872 0.2340537581931034 1.0 0.8825338561231298 84 O43681,P07602,P00403,P50336,P03886,P04114,P49366,Q13423,O43772,P21964,Q9NSD9,P35914,P42892,O75844,P16435,P06280,Q9UMS0,P20700,Q10713 19 +Peripheral hypermyelination 0.8569766479240537 1.1892326458387843 0.234348131407645 1.0 0.8825338561231298 3 Q9NR77 1 +Abnormal circulating acetylcarnitine concentration 0.6019741643305119 1.1883707609672234 0.2346873706598642 1.0 0.8825338561231298 7 O43772,P23786 2 +Saccadic smooth pursuit 0.6479384169306495 1.1811785353155395 0.2375318063772884 1.0 0.8825338561231298 5 Q10713 1 +Hyperthyroidism 0.5590938038996599 1.175934180641572 0.2396211788038673 1.0 0.8825338561231298 9 P21964,Q92766,Q9BUK6 3 +Progeroid facial appearance 0.5988958213135943 1.174159893337453 0.2403309871724503 1.0 0.8825338561231298 7 O75844,O75431 2 +Long upper lip 0.8346253229974105 1.171189357767247 0.241522672038787 1.0 0.8825338561231298 2 Q9BZK7 1 +Abnormality of the vertebral endplates 0.6129826085332 1.169486773821084 0.2422075669705958 1.0 0.8825338561231298 6 Q9NR45 1 +Venous insufficiency 0.6129652571848931 1.1694090371240788 0.242238870532266 1.0 0.8825338561231298 6 P21964,Q92766 2 +Capillary hemangioma 0.5977441227662939 1.1688422657988875 0.2424671880253082 1.0 0.8825338561231298 7 P16435,Q9UHX1 2 +Morphological abnormality of the corticospinal tract 0.4630208195389984 1.1659177653629191 0.2436476954904338 1.0 0.8841754705628188 16 P00846,O75298 2 +Dysesthesia 0.6121115398388103 1.1655842058695551 0.2437825966297926 1.0 0.8841754705628188 6 Q9NR77 1 +Migraine 0.4456457580460699 1.1623371122047346 0.2450985572842281 1.0 0.886040046690904 23 Q96RR1,Q9NZ08,P00403,O96011,O60313,P03886,O43791,Q13586 8 +Supernumerary bones of the axial skeleton 0.643341196902061 1.1615152793220422 0.2454324131912093 1.0 0.886040046690904 5 Q9UHX1 1 +Coxa vara 0.475364449428111 1.1575078863563175 0.2470649191285674 1.0 0.8862559987091837 15 Q96HY6,O95831,O75718,Q9Y487,Q9NUQ7 5 +Abnormal large intestine physiology 0.4449355898287584 1.1570649894427938 0.2472458092426834 1.0 0.8862559987091837 23 P21964,O43681,O75298,P07602,P06280,P20700 6 +Cachexia 0.4616631666846292 1.1568750370015566 0.2473234189546578 1.0 0.8862559987091837 16 Q99720 1 +Atlantoaxial abnormality 0.8466039405275222 1.151661169670152 0.2494603345250778 1.0 0.8862559987091837 3 Q8NCH0 1 +Aplasia hypoplasia of the uterus 0.4606580009489003 1.150178525900824 0.2500703489064251 1.0 0.8862559987091837 16 Q16740,Q9UNW1 2 +Weakness due to upper motor neuron dysfunction 0.3627394155592999 1.1485367991933109 0.2507470306082409 1.0 0.8862559987091837 136 P00846,O43681,Q9BRK0,P07602,P00403,O95831,P50336,P03886,Q9HA77,Q7KZN9,Q13510,Q9H6K4,Q9UBX3,Q5XKP0,Q13423,Q9Y619,Q9NZ08,P35914,P51572,O43791,Q6DKK2,P50416,O75298,O75787,P20700,Q9P0J0,P49902,Q8IY17 28 +Asymmetric septal hypertrophy 0.8288113695090285 1.148333690803974 0.2508308359430018 1.0 0.8862559987091837 2 P54802 1 +Abnormality of ocular smooth pursuit 0.4469282268895457 1.1479917208353836 0.2509719816544722 1.0 0.8862559987091837 22 Q10713,P41440,P46977 3 +Photophobia 0.4035815379438733 1.1477159281528622 0.2510858535257718 1.0 0.8862559987091837 34 P48449,Q9NZ08,P07602,Q13432,P04439,Q8WWY3,Q6P4Q7,O00203,Q9NZJ7,P51648,Q8IY17 11 +Scanning speech 0.8449111470113126 1.1455382669728744 0.2519862530546199 1.0 0.8862559987091837 3 O14773,Q8IY17 2 +Bilateral tonic clonic seizure with focal onset 0.827842377260967 1.1445292349605476 0.252404220798486 1.0 0.8863497055946834 2 P07602 1 +Hyperesthesia 0.827842377260967 1.1445292349605476 0.252404220798486 1.0 0.8863497055946834 2 P07602 1 +Nasogastric tube feeding in infancy 0.5249125835487274 1.1430577562606898 0.2530146119522318 1.0 0.8870197568666602 11 Q9UHX1,O75648,P07602,P61978 4 +Transposition of the great arteries 0.606048959631993 1.1384210910327293 0.2549446912864559 1.0 0.8882067515501625 6 O75844,Q9NVR5 2 +Abnormal larynx morphology 0.4350559454105067 1.137739190516339 0.2552294035949254 1.0 0.8882067515501625 25 P21964,P16435,Q96HY6,Q92766,P07602,Q13510,Q9UHX1 7 +Color vision defect 0.4838931976976455 1.1305377543078696 0.2582496991972665 1.0 0.8925291997784777 14 Q9H6K4,Q9H061 2 +Prematurely aged appearance 0.4056334046728235 1.1287320095734283 0.2590109018212221 1.0 0.8929371272832086 38 O75844,Q9UP83,O95453,Q13126,Q9BZK7,Q9Y487,O75431 7 +Abnormal nervous system electrophysiology 0.3106921118091907 1.1277794851979803 0.2594130593359736 1.0 0.8929644063768697 172 Q99720,O43681,Q14108,Q96F07,P48449,P07196,P07602,P00403,O95831,Q71SY5,P03886,Q9HA77,O15269,P50897,Q8NHS3,P49366,O60762,Q9UBX3,Q96A33,P13073,P21964,Q9Y619,P50570,O75381,Q96N66,O75503,P35914,Q9NUQ7,Q9UBB6,Q9UBB4,O95202,Q8NC96,Q9NR77,Q08J23,P20700,O14773 36 +Foot acroosteolysis 0.6913749934654487 1.1247007429364155 0.2607158667862237 1.0 0.894110198776557 4 O75844 1 +Osteolysis involving bones of the feet 0.6913749934654487 1.1247007429364155 0.2607158667862237 1.0 0.894110198776557 4 O75844 1 +Increased serum lactate 0.3938337383098623 1.121812391065844 0.2619422166085352 1.0 0.894110198776557 115 P00846,Q9BWD1,P00403,O95831,Q70HW3,P03886,Q9Y584,Q9HA77,Q7KZN9,Q86VD7,Q9UBX3,Q53H12,Q5XKP0,P13073,P22695,P35914,P20674,Q6P4A7,O43819,Q9P0J0 20 +Neonatal hypoglycemia 0.4824652172702584 1.121733115014094 0.2619759321088004 1.0 0.894110198776557 14 O43772 1 +Abnormal aortic valve morphology 0.4066965860848219 1.121063603476404 0.2622607898523981 1.0 0.894110198776557 40 O75844,P21964,Q92766,P37268,Q6PGP7,O15294,P06280,Q9UHX1,Q9BXW9 9 +Polar cataract 0.821705426356576 1.1204685030803527 0.2625141673601749 1.0 0.894110198776557 2 P08670 1 +Pace of progression 0.312558087913156 1.1203623464927446 0.2625593837004074 1.0 0.894110198776557 158 Q99720,Q14108,Q9BRK0,O95470,P07196,O00584,Q9BQP7,O95831,O00400,Q13586,Q8NHS3,Q13510,O60762,Q03252,Q5XKP0,Q8N1F7,P50570,P50402,O14653,Q9P0J0,Q9BUF5,O75298,O75787,Q13126,Q9NR77,P54802,P20700,Q10713,O14773,P41440,Q8IY17 31 +Central hypoventilation 0.6019550519034945 1.1200788982167516 0.2626801420195028 1.0 0.894110198776557 6 O43819 1 +Abnormal urine carbohydrate level 0.5334270243078669 1.1190910414273152 0.2631013013176932 1.0 0.894110198776557 10 P16278,Q6PGP7,P10253,Q7Z4W1,Q9UJS0 5 +Diffuse cerebral atrophy 0.4456368395256406 1.1177496637630544 0.2636739251975641 1.0 0.895384468624412 21 Q9UP83,Q9H936,P16278,P07602,O75787,Q9NZJ7,Q10713,Q9HA77 8 +Adducted thumb 0.4282065852272864 1.116063169777726 0.2643950958464578 1.0 0.8964893594195015 26 Q04656,Q96AA3,P83436,O43175,P42892,P57740,Q86XL3,Q71SY5,Q8NCH0,Q9Y4P3 10 +Abnormalities of placenta or umbilical cord 0.4686011064464608 1.1142008571719684 0.2651930277896888 1.0 0.8970963818181331 15 O75844,P16435,Q6PGP7,P16278 4 +Irregular epiphyses 0.6877059059457209 1.11005690265719 0.2669745069760298 1.0 0.8988250189114763 4 Q9NR45 1 +Clonus 0.4028865689298125 1.1099985342172514 0.2669996581157214 1.0 0.8988250189114763 31 Q99720,Q9Y619,O75298,P07602,Q9BQT8,O75787,O00400,P20700 8 +Laryngomalacia 0.4924342093175364 1.1097141936478616 0.267122204644123 1.0 0.8988250189114763 13 P21964,Q92766,P07602,P16435 4 +Hypoplasia of the frontal lobes 0.5994748071363474 1.1089675131343333 0.2674441968980492 1.0 0.8988250189114763 6 Q86XL3 1 +Abnormal blood transition element cation concentration 0.4920871052208283 1.107649242586912 0.2680133280475911 1.0 0.8988250189114763 13 Q9Y487,Q6PGP7,O43819 3 +External ophthalmoplegia 0.4506806904953334 1.1043321312486278 0.2694490895544779 1.0 0.8988250189114763 18 P50570,Q96RR1,P00403,Q9BQP7,P03886,Q13586 6 +Increased ldl cholesterol concentration 0.5302015987011569 1.1021596853719626 0.2703922551449382 1.0 0.9004797538671261 10 Q9UJS0,P50402,P04114,Q8N511 4 +Hyperlipoproteinemia 0.5302015987011569 1.1021596853719626 0.2703922551449382 1.0 0.9004797538671261 10 Q9UJS0,P50402,P04114,Q8N511 4 +Limb tremor 0.5977943973458966 1.1014400378930371 0.2707051880053119 1.0 0.9004797538671261 6 Q9NR77,Q9HA77,P20700 3 +Wide cranial sutures 0.5568120056610739 1.096535165910013 0.2728446426860089 1.0 0.9027927394055208 8 O75844 1 +Abnormal blood sodium concentration 0.5563500713099387 1.0942904166525032 0.2738276270389028 1.0 0.9027927394055208 8 P50336,Q13423 2 +Ulnar deviation of the wrist 0.6272708239154196 1.0928316428095035 0.2744677257049259 1.0 0.9027927394055208 5 P16435,P16278 2 +Visual impairment 0.3472593832743766 1.0901884963946789 0.2756301196431079 1.0 0.9027927394055208 266 P00846,O43681,P52732,P48449,P07602,P00403,O15294,Q9NPL8,O95831,Q71SY5,Q8WWY3,P03886,O43505,Q9HA77,Q5BJH7,O43676,Q9UP83,P50897,Q9H061,P06865,P37268,Q8NHS3,Q9BVA1,Q9H6K4,O60762,Q96A33,Q5XKP0,Q9BXW9,P78318,P16278,Q13277,O75381,Q9NZ08,Q96N66,O75503,Q13432,Q5KU26,O00203,Q96B26,O75380,Q9NR50,Q9UHX1,Q9NUQ7,Q86Y39,O96000,Q9UBB6,Q8N3U4,Q9Y375,Q96RR1,Q6P4A7,Q96CU9,O43819,Q08J23,O75648,Q96TA2,P20700,Q10713,Q8TB37,O14773,Q8IY17 60 +Abnormality of the foot musculature 0.8139534883720952 1.0901666848535432 0.2756397258005916 1.0 0.9027927394055208 2 P50570 1 +Abnormality of the odontoid process 0.6263641181764766 1.088960226618923 0.2761714253984395 1.0 0.9027927394055208 5 P16278 1 +Abnormality of the musculature of the lower limbs 0.4322276221397909 1.0876935160076364 0.2767304311263667 1.0 0.9027927394055208 24 P00846,P50570,P07196,P50402,Q9NR77,Q8WXH0 6 +Progressive peripheral neuropathy 0.8281098546042123 1.0849240600195609 0.2779552907202112 1.0 0.9027927394055208 3 O43681,P07602 2 +Biliary tract neoplasm 0.8281098546042123 1.0849240600195609 0.2779552907202112 1.0 0.9027927394055208 3 O43681,P07602 2 +Vegetative state 0.8281098546042123 1.0849240600195609 0.2779552907202112 1.0 0.9027927394055208 3 O43681,P07602 2 +Neoplasm of the gallbladder 0.8281098546042123 1.0849240600195609 0.2779552907202112 1.0 0.9027927394055208 3 O43681,P07602 2 +Abnormal pupillary light reflex 0.828109854604212 1.0849240600195602 0.2779552907202114 1.0 0.9027927394055208 3 Q9NR77,P07602 2 +Slow pupillary light response 0.828109854604212 1.0849240600195602 0.2779552907202114 1.0 0.9027927394055208 3 Q9NR77,P07602 2 +Thick upper lip vermilion 0.554310283268303 1.0843780988334388 0.2781971902691671 1.0 0.9027927394055208 8 Q9UNW1 1 +Phenotypic variability 0.4068613064410254 1.082423333534582 0.2790644647664921 1.0 0.9027927394055208 99 P00846,P52732,O95470,P07196,P07602,P00403,P57740,Q8WWY3,Q70HW3,P03886,Q9NZJ7,Q13586,Q9H061,Q13510,Q9BVA1,Q9NQT5,O60762,Q53H12,O14979,O95453,Q92733,O60313,Q9UBB4,Q9BUF5,Q6P4A7,Q9NR77,Q9Y375,Q9UEY8,Q8TB37 29 +Decreased plasma carnitine 0.4876370865929142 1.081170451104383 0.2796212995181344 1.0 0.9027927394055208 13 O43772,P35914,P23786,O75648,O75880 5 +Hypoketotic hypoglycemia 0.5400480708161036 1.0798594365834917 0.2802047788016772 1.0 0.9027927394055208 9 O43772,P23786,P31751 3 +Glomerular sclerosis 0.404442771126844 1.0763831117093012 0.281755952165301 1.0 0.9058583841794278 30 Q8N1F7,Q14108,O95470,P00403,P03886,O75431 6 +Prominent nasal bridge 0.406658814795754 1.074480981778864 0.2826071641350378 1.0 0.9079506762636322 46 P21964,Q5JRA6,P78318,Q92766,P49366,Q08J23,O43791,P20700,Q10713,P42892,P13073 11 +Insidious onset 0.6778667176235605 1.070840576354396 0.2842411187372633 1.0 0.9080237034356036 4 Q9NR77 1 +Abnormal sensory nerve conduction velocity 0.6216528831453927 1.068853342045902 0.2851357588864005 1.0 0.9080237034356036 5 Q9NR77 1 +Dermal atrophy 0.4330168682147898 1.068469036301006 0.2853089903648838 1.0 0.9080237034356036 23 O75844,Q15392,Q8NCH0,Q9NWM8 4 +Abnormality of the brainstem white matter 0.8233939422358459 1.067968612870294 0.285534670241887 1.0 0.9080237034356036 3 Q10713 1 +Dilated cardiomyopathy 0.4006443666189541 1.0662419847308444 0.2863142675685379 1.0 0.9080237034356036 40 P00846,P42167,P16278,Q96RR1,O75306,P00403,P35914,P23786,Q9BQP7,P57740,O43819,P03886,Q8WXH0,Q16836 14 +Corneal neovascularization 0.676660832597682 1.0660403375498784 0.2864054078342477 1.0 0.9080237034356036 4 P21964 1 +Multiple suture craniosynostosis 0.676660832597682 1.0660403375498784 0.2864054078342477 1.0 0.9080237034356036 4 P21964 1 +Hypertensive crisis 0.676660832597682 1.0660403375498784 0.2864054078342477 1.0 0.9080237034356036 4 P21964 1 +Tricuspid atresia 0.676660832597682 1.0660403375498784 0.2864054078342477 1.0 0.9080237034356036 4 P21964 1 +Periventricular white matter hyperintensities 0.5503179095365662 1.0649777835087282 0.2868859834747637 1.0 0.9080237034356036 8 O43681,O75503 2 +Respiratory distress 0.4065453468603568 1.0598738408223534 0.2892019979290432 1.0 0.9110626722511334 48 P00846,P07602,Q13510,P23786,O95831,P03886,Q9UHX1 7 +Cerebral hypomyelination 0.4600075257021087 1.0591246298418089 0.2895430243524264 1.0 0.9110626722511334 15 P51572,O43175,O75746,Q9H553,Q9NR50 5 +Cortical dysplasia 0.4119144006903186 1.056172856900842 0.2908892491717512 1.0 0.9125223066334645 28 P07437,Q9UBB6,Q96N66,Q96PU5,Q71SY5,Q9BVA1,Q08J23,O43505 8 +Tremor by anatomical site 0.4067735603514926 1.0531131125518771 0.292289153846613 1.0 0.9125223066334645 29 Q9NR77,Q99720,P07196,Q9HA77 4 +Spastic gait 0.4201320485925405 1.0526632105952696 0.2924953755031048 1.0 0.9125372252266284 26 Q9Y619,O75298,Q9BRK0,O75787,O00400,P20700,P49902 7 +Abnormal csf metabolite level 0.4127700680567077 1.0518106169929045 0.2928864469961183 1.0 0.912707349218512 62 O43676,P00846,O96000,Q96CU9,P00403,Q9NPL8,O43819,O95831,Q8TB37,P03886,Q9Y375,Q9P0J0,O75380,Q86Y39,Q7KZN9,P13073 16 +Impaired distal vibration sensation 0.5853839687096752 1.045877362239106 0.295617657343586 1.0 0.9141306014711904 6 Q9BRK0,P20700 2 +Developmental stagnation 0.5710747992870677 1.045660009495109 0.2957180324424797 1.0 0.9141306014711904 7 P16278,O43175 2 +Abnormal gastrointestinal motility 0.4230488000451549 1.0452226267937088 0.2959200881485522 1.0 0.9141306014711904 25 P06280,P61978,P00403,P50336,P03886 5 +Abnormal urine cytology 0.394225402669438 1.0444739441337725 0.2962661681230161 1.0 0.9141306014711904 36 Q14108,P09601,P06280,Q9BZK7,Q03252 5 +Abnormal circulating aromatic amino acid concentration 0.815956967063278 1.0412899812099814 0.2977409851221366 1.0 0.9141306014711904 3 Q9UJS0 1 +Abnormality of femur morphology 0.4127701093322196 1.0405199699574124 0.2980983910518313 1.0 0.9141306014711904 67 Q9Y2D4,Q96HY6,Q6NUQ1,P07602,O95831,Q9NZJ7,Q9Y487,Q7LGA3,Q32P28,Q96A33,Q9BXW9,Q9Y619,P16278,Q9NR45,Q9NUQ7,Q9UHX1,O75431,O75844,P16435,Q9BV10,P06280,O75718 22 +Hyperactive deep tendon reflexes 0.532012749075994 1.0393100198124108 0.298660576339711 1.0 0.9141306014711904 9 Q9NR77 1 +Clonic seizure 0.5837632304435558 1.0386268339869116 0.2989783209182504 1.0 0.9141306014711904 6 P07602,Q9NZJ7 2 +Abnormal involuntary eye movements 0.3471761690975842 1.0343056846740617 0.3009932801509443 1.0 0.9141306014711904 275 P00846,Q99720,Q96F07,P52732,P07196,P07602,O15294,Q9NPL8,O00584,O95831,Q9BZK7,O00400,P03886,Q8WWY3,O75027,Q7KZN9,O43676,Q9BT22,Q9H061,Q15392,Q13510,Q9NVI7,Q9H6K4,O60762,Q53H12,Q5XKP0,Q9BXW9,O43772,P78318,Q13277,Q9NR45,O75381,Q16625,O75503,Q5KU26,O00203,O75380,Q6DKK2,Q86Y39,O96000,Q10713,Q9UBB4,Q9Y375,Q9UNW1,Q96RR1,O95202,Q96CU9,Q05086,Q8NC96,Q9NR77,O43819,Q08J23,O14773,O75648,P20700,Q9P0J0,Q9UEY8,Q8TB37,P49902,P41440,Q8IY17 61 +Abnormality of the shoulder girdle musculature 0.4044923364208998 1.0340761954834312 0.3011005437262397 1.0 0.9141306014711904 29 O14979,Q96RR1,P07196,P07602,P50402,O60313,Q8WXH0,Q9NZJ7,Q9Y487 9 +Elevated systolic blood pressure 0.7990956072351222 1.0324115365960298 0.3018793697754334 1.0 0.9141306014711904 2 P42892 1 +Elevated diastolic blood pressure 0.7990956072351222 1.0324115365960298 0.3018793697754334 1.0 0.9141306014711904 2 P42892 1 +Elevated mean arterial pressure 0.7990956072351222 1.0324115365960298 0.3018793697754334 1.0 0.9141306014711904 2 P42892 1 +Cns demyelination 0.4911048835537022 1.0316572142844147 0.3022327274966998 1.0 0.9141306014711904 12 Q9NR50,P07602 2 +Abnormal social behavior 0.4115135734375806 1.0282117763983714 0.3038502200590705 1.0 0.9143244344923336 67 O43681,O75306,P07602,Q9NPL8,P03886,Q9NZJ7,O43676,Q5XKP0,Q5KU26,O75380,O75746,Q9UHX1,Q86Y39,O96000,Q96RR1,Q96CU9,Q9Y375,Q9P0J0,Q8TB37 19 +Cold induced muscle cramps 0.8122294476039229 1.027948097153377 0.3039742431608214 1.0 0.9143244344923336 3 Q9NR77 1 +Abnormal urine protein level 0.4058988290937897 1.024036854252282 0.3058178679020267 1.0 0.9143244344923336 53 Q8N1F7,Q5JRA6,Q14108,O95470,P09601,P00403,P35670,P06280,P03886,Q03252,O75431 11 +Truncus arteriosus 0.5286977823536061 1.022585413914147 0.3065039089701158 1.0 0.9143244344923336 9 P21964,Q9UHX1 2 +Abnormality of the umbilical cord 0.5403889263116358 1.0167451048812923 0.3092747026195823 1.0 0.9143244344923336 8 O75844,P16435 2 +Abnormal glycosylation 0.4155136734870445 1.016372016630278 0.3094522660648857 1.0 0.9143244344923336 26 Q9UP83,Q9BT22,O75787,P46977,Q9Y487,Q8N511 6 +Atrophic scars 0.5786540392983728 1.0157822791990867 0.3097330764536616 1.0 0.9143244344923336 6 Q8NCH0,Q9NWM8 2 +Turricephaly 0.5399306783551341 1.0145199865496068 0.3103346974348779 1.0 0.9143244344923336 8 P21964,P16435 2 +Fasciculations 0.3905497092943047 1.0114137728435748 0.3118184319562496 1.0 0.9166121210154958 36 Q9UNW1,P07602,Q9BQT8,Q13510,P06280,O43819,O95831 7 +Aplasia hypoplasia of the 5th finger 0.4523225352996071 1.009853902786464 0.3125652907024734 1.0 0.9166121210154958 15 Q9UHX1 1 +Cerebral visual impairment 0.4078722459205322 1.0078372309931896 0.3135326091594439 1.0 0.9166121210154958 61 Q9UBB6,Q8N3U4,Q9UP83,Q96RR1,P37268,Q96N66,P00403,Q71SY5,Q08J23,P03886,O60762,Q96A33,Q9NUQ7,Q5BJH7,P20700 15 +Primary amenorrhea 0.421497645648791 1.0064359690038192 0.3142058984661742 1.0 0.9166121210154958 24 P16435,Q9BUK6,Q96RR1,Q9NR50,Q16740 5 +Abnormal placental size 0.6615804082423428 1.0061486120096743 0.3143440874070118 1.0 0.9166121210154958 4 O75844,Q6PGP7 2 +Stuttering 0.8056005290097962 1.0042746585030526 0.3152462448790938 1.0 0.9166121210154958 3 P03886 1 +Status epilepticus 0.3954937757815642 1.0027088284824677 0.3160013690008489 1.0 0.9166121210154958 42 Q9UBB4,Q96F07,P52732,Q96RR1,Q15392,P07602,Q13510,Q8NC96,Q9Y487,Q03252,Q9HA77,P42892 12 +Ureteral duplication 0.5247037655242772 1.0024409284044815 0.3161306831258095 1.0 0.9166121210154958 9 O75844 1 +Osteolysis 0.4174557343296239 1.002083394516483 0.3163033171827742 1.0 0.9166121210154958 25 O75844,Q14108 2 +Progressive hearing impairment 0.4738753590023357 0.9992634648225962 0.3176670790291855 1.0 0.9166121210154958 13 Q96RR1,P00403,O96011,O60313,P03886 5 +Small earlobe 0.6050741174181427 0.9982536552126716 0.3181563744324251 1.0 0.9171974840529458 5 P21964,Q92766 2 +Abnormal response to endocrine stimulation test 0.8034149472944996 0.9964852700193892 0.3190144205199954 1.0 0.9181291772271786 3 Q13423 1 +Progressive spastic paraplegia 0.385323444803863 0.9945566371587272 0.319951946369241 1.0 0.9196588306171714 33 Q9P0J0,P00846,Q7KZN9,Q8IY17 4 +Chronic rhinitis 0.6574014221073056 0.9896043928658276 0.3223675220200737 1.0 0.921764607114128 4 Q9NVR5,P51798,Q9BV10 3 +Retinal thinning 0.7877906976744018 0.9887969179522677 0.3227625125012237 1.0 0.921764607114128 2 P51648 1 +Submucous cleft of soft and hard palate 0.4222978021219558 0.9886843516159152 0.3228176013508879 1.0 0.921764607114128 23 O75844,Q8N3U4,Q9Y619,Q7LGA3,Q15392,Q08J23,O43505,Q96DF8 8 +Abnormal cardiac ventricular function 0.4291569363168567 0.9823655412005357 0.3259197961310134 1.0 0.923698504752452 20 O75844,P04114,P03886,P00403 4 +Abnormal bone structure 0.3000874122541928 0.9803768837650596 0.3269001160314591 1.0 0.9242785948996404 167 Q14108,Q96HY6,P07602,P35670,P57740,O95831,Q9Y487,Q9NWM8,Q15392,Q13510,Q86XL3,Q32P28,Q9BXW9,Q9NSD9,Q9Y619,Q5JRA6,P16278,Q13277,O95453,O75381,P61978,Q9NUQ7,O75431,O75844,P38435,Q9BV10,Q96RR1,O95202,Q9HC07,P06280,Q13126,P54802,O75718,Q9Y375 34 +Deviation of the 2nd finger 0.5703782791859924 0.978826477804258 0.3276657245775087 1.0 0.9242785948996404 6 Q9H6K4 1 +Decreased absent ankle reflexes 0.459016650145528 0.9770519181765353 0.3285434498807529 1.0 0.9244952706881708 14 P07196,O75787,Q9H6K4,Q96RR1 4 +Hypertrophic cardiomyopathy 0.3899541356836008 0.9682637854322002 0.3329126462064635 1.0 0.9269625832308342 107 P00846,O75306,P00403,Q9NPL8,P15586,P03886,Q16836,Q7KZN9,O43676,Q9H061,Q9NVI7,Q8WXH0,Q53H12,Q5XKP0,Q13423,Q9BXW9,O95817,P16278,P50402,O75380,P50416,Q86Y39,O96000,Q96IX5,Q96CU9,P06280,P83436,O43819,P54802,Q9Y375,Q9P0J0,Q8TB37 32 +Brisk reflexes 0.4130556535963261 0.9681422807972208 0.3329733163981039 1.0 0.9269625832308342 25 P20674,Q99720 2 +Concentric hypertrophic cardiomyopathy 0.7934604871467684 0.9611153881069472 0.3364941532778855 1.0 0.9269625832308342 3 P03886 1 +Abnormal circulating fatty acid anion concentration 0.4446880882490122 0.9609228219489064 0.3365909748246389 1.0 0.9269625832308342 15 O43772,P35914,P23786,O75648,O75880 5 +Toxemia of pregnancy 0.5654654718502509 0.9569225095354514 0.3386063688365606 1.0 0.9269625832308342 6 O43772 1 +Ectopic calcification 0.4003883666202093 0.9568706024176794 0.3386325709235234 1.0 0.9269625832308342 56 O75844,Q9NSD9,P38435,O95453,Q16625,P00403,O00584,P23786,P03886,O75431 10 +Redundant skin 0.4177931010709074 0.95515349410185 0.339500080075708 1.0 0.9269625832308342 23 Q9Y487,O96000,Q8NCH0 3 +Ventriculomegaly 0.3034433534316844 0.9545039669535136 0.339828602246796 1.0 0.9269625832308342 177 P00846,Q96F07,P07602,Q9NPL8,O00584,Q9BZK7,Q71SY5,Q8NCH0,Q9Y487,O43505,Q9UP83,Q15392,Q86XL3,Q9BVA1,O60762,Q03252,Q9BXW9,P07437,P16278,O95453,Q9NR45,Q16625,Q5KU26,Q9NVR5,Q9UHX1,Q9BV10,O95202,O75787,P23786,O43819,P20700,Q10713 32 +Generalized edema 0.7903854339525519 0.950227227615852 0.3419968066114784 1.0 0.9269625832308342 3 Q9NSD9 1 +Panniculitis 0.5639427068151217 0.9501392558297012 0.3420414988880049 1.0 0.9269625832308342 6 P28070 1 +Carpal bone hypoplasia 0.5637131746979582 0.9491170557015884 0.3425610807609509 1.0 0.9269625832308342 6 Q9NR45 1 +Aplasia hypoplasia involving the carpal bones 0.5637131746979582 0.9491170557015884 0.3425610807609509 1.0 0.9269625832308342 6 Q9NR45 1 +Abnormal thoracic spine morphology 0.4069313711342683 0.9489199962766508 0.3426613035800798 1.0 0.9269625832308342 26 O75844,O95831,Q9UHX1 3 +Hypolipoproteinemia 0.5137188259321707 0.9470918542904144 0.3435919751447127 1.0 0.9269625832308342 9 P37268,Q15800,Q9UJS0 3 +Abnormal choroid morphology 0.4136324267858489 0.9468577744188672 0.3437112571385743 1.0 0.9269625832308342 24 O60826,Q10713,Q9Y619,P52732,Q96J42,P35222,O75381,O75695,O96011,P04439,O60315,P40855,O43505,Q96AX1,Q5XKP0,Q8IY17 16 +Abnormal chorioretinal morphology 0.4136324267858489 0.9468577744188672 0.3437112571385743 1.0 0.9269625832308342 24 O60826,Q10713,Q9Y619,P52732,Q96J42,P35222,O75381,O75695,O96011,P04439,O60315,P40855,O43505,Q96AX1,Q5XKP0,Q8IY17 16 +Hyporeflexia of upper limbs 0.7894066382231939 0.9467654859971898 0.3437582925713784 1.0 0.9269625832308342 3 Q9NR77 1 +Generalized clonic seizure 0.5927265328543299 0.9458909846414942 0.3442041922202865 1.0 0.9269625832308342 5 P07602,Q9NZJ7 2 +Barrel shaped chest 0.6460892049127354 0.9449596582211308 0.3446794721483914 1.0 0.9269625832308342 4 Q96AX1,P04066,Q32P28 3 +Abnormal retinal morphology 0.3166756160274684 0.9421160779419266 0.3461332137910666 1.0 0.9275435815691048 208 P00846,Q96F07,P52732,O75306,P07602,P00403,Q8WWY3,Q8NCH0,P03886,Q9NZJ7,P04114,Q9Y487,O43505,Q7KZN9,P50897,P06865,Q92766,Q8NHS3,Q13510,O60762,Q5XKP0,P07437,P21964,Q9Y619,Q5JRA6,P16278,P50570,O75381,Q9NZ08,O75503,Q13432,P51648,Q9NVR5,Q9UHX1,Q10713,P38435,Q9BV10,Q9BUK6,O95202,Q96CU9,Q8NC96,O43819,P10619,O75648,Q9Y375,Q9P0J0,Q96DF8,O14773,Q8IY17 49 +Gangrene 0.4881086039109517 0.9418437711214824 0.3462726315666022 1.0 0.9275435815691048 11 Q9BZK7,Q9NZ08,Q8NBM4,P52732 4 +Hydrocele testis 0.5245124094834107 0.939742317534164 0.3473497529961795 1.0 0.9284674626324402 8 Q9NVI7,O60315,Q9UBX3,O96011 4 +Abnormality of vitamin d metabolism 0.5122090870944255 0.9394934873967954 0.3474774344129843 1.0 0.9284674626324402 9 Q9NSD9 1 +Reduced forced expiratory volume in one second 0.7748708010335834 0.9393593080842988 0.3475462978057555 1.0 0.9284674626324402 2 O95453 1 +Tissue ischemia 0.4266402515663017 0.9392319678139402 0.3476116592990328 1.0 0.9284674626324402 18 O75844,P06280 2 +Flat forehead 0.643990026580859 0.9366998725998884 0.3489129618034707 1.0 0.9297504217468956 4 Q8NCH0 1 +Abnormal sputum 0.5587262514227178 0.9269265208429838 0.353964686351937 1.0 0.9337162653355564 6 Q9NVR5,Q9NZ08 2 +Young adult onset 0.4853036145022265 0.9265356175593952 0.3541676960155637 1.0 0.9337162653355564 11 O15118,P07602 2 +Cyanosis 0.4245353093825108 0.9247872644852708 0.3550765764958776 1.0 0.9337162653355564 18 O43772 1 +Capillary malformation 0.4720499045170934 0.9228861907842404 0.3560665177350293 1.0 0.935061637878077 12 Q9UHX1 1 +Knee clonus 0.7697028423772427 0.9197202119199532 0.3577189876311299 1.0 0.9361450109584164 2 O75298 1 +Acute coronary syndrome 0.4228413180372423 0.9131667039344952 0.3611548726214226 1.0 0.939675560631368 18 O75844,Q9NZ08,P06280 3 +Abnormality of facial adipose tissue 0.637959360816467 0.9130187292811144 0.3612326912224839 1.0 0.939675560631368 4 O75844 1 +Abnormal protein glycosylation 0.4146729095763435 0.9120340966842524 0.3617507687960068 1.0 0.939675560631368 22 Q9UP83,Q9BT22,O75787,Q9Y487,Q8N511 5 +Abnormal arterial physiology 0.4054353833994428 0.9093852269792856 0.3631468170588539 1.0 0.9399548229541268 25 O75844,Q9NZ08,P06280 3 +Abnormal circulating glutamine family amino acid concentration 0.554385527935619 0.9076423577214136 0.3640672075277285 1.0 0.9399548229541268 6 O96000,P20674 2 +Abnormality on pulmonary function testing 0.4229077386307096 0.9049055515477114 0.3655154257109891 1.0 0.9399548229541268 17 Q9BQT8,P16278 2 +Generalized abnormality of skin 0.3161556368281191 0.9022079299365396 0.3669464231341854 1.0 0.9399548229541268 212 P00846,Q14108,Q6NUQ1,P00403,Q9BZK7,Q8IZA0,Q8NCH0,P03886,P50336,Q9Y487,Q13586,Q9NWM8,Q9UJS0,O15269,Q9UP83,P37268,Q92766,O15118,O60762,Q03252,Q9BXW9,O43772,P21964,P61916,P16278,P98194,O95453,O75381,Q16625,P35914,O43791,P51648,O75431,O75844,P38435,P22830,P06280,O75787,Q13126,Q08J23,Q06136 41 +Abnormality of thalamus morphology 0.4353829863156894 0.9013553033949948 0.3673994381324066 1.0 0.9399548229541268 15 O43819,Q96RR1 2 +Cerebral dysmyelination 0.552807752949039 0.9006407276736135 0.3677793726444907 1.0 0.9399548229541268 6 P07602,Q9NZJ7 2 +Abnormality of coordination 0.3518204223953329 0.8992003028825089 0.3685459790486571 1.0 0.9401622982488348 315 P00846,Q99720,O43681,Q14108,Q96F07,O75306,O95470,P07196,P07602,P00403,Q9NPL8,O00584,P35670,O95831,P57740,P03886,P04114,Q9Y487,Q13586,O75027,Q7KZN9,O43676,Q86VD7,Q9UP83,P50897,O14949,Q8NHS3,Q13510,Q9NVI7,Q9BVA1,O15118,Q9H6K4,O60762,Q03252,Q5XKP0,P07437,Q9Y619,P61916,P16278,O95453,Q9NR45,Q9NZ08,O75381,O75503,P35914,O75380,Q6DKK2,O14653,Q86Y39,O96000,Q10713,Q9UBB4,Q9Y375,Q9BUK6,O75298,Q96RR1,Q6P4A7,O95202,Q96IX5,Q96CU9,Q05086,Q8NC96,O75787,Q9NR77,O43819,Q96TA2,P20700,Q9P0J0,Q8TB37,O14773,P41440,Q8IY17 72 +Microretrognathia 0.4191609994806962 0.898555118388647 0.3688896739632135 1.0 0.9401622982488348 19 Q9UHX1,Q8NCH0 2 +Fair hair 0.6339256789893897 0.8972218455164097 0.369600550505065 1.0 0.9406126369595194 4 O00203 1 +Abnormal tongue physiology 0.4199524888212523 0.8933596439711272 0.3716646068261768 1.0 0.9411071374637124 18 O95831,Q13510 2 +Alveolar ridge overgrowth 0.762596899224785 0.8928552885247618 0.3719346736549376 1.0 0.9412648445010432 2 Q15392 1 +Metaphyseal dysplasia 0.4902002325776383 0.8923808001518847 0.3721888586357091 1.0 0.9413822052594988 10 O95831,Q9HC07,Q9NUQ7 3 +Hypoproteinemia 0.7619509043927489 0.8904213606820809 0.3732396768568748 1.0 0.9426518520831538 2 Q9UJS0 1 +Generalized lipodystrophy 0.7733214882309414 0.8901745751523545 0.3733721543899992 1.0 0.9426518520831538 3 O75844 1 +Joint hemorrhage 0.761627906976725 0.8892049324751913 0.3738929524364023 1.0 0.9426518520831538 2 P38435 1 +Increased circulating antibody level 0.478368331980583 0.88873136920137 0.3741474680012164 1.0 0.9426518520831538 11 Q14108 1 +Heparan sulfate excretion in urine 0.772442781391917 0.8871004114790203 0.375024842558731 1.0 0.9427184848084108 3 P54802 1 +Splenomegaly 0.3957354260751807 0.8830731059050824 0.3771967738680606 1.0 0.9437843139894132 86 Q14108,Q96HY6,Q6NUQ1,Q9NRW7,P07602,P35670,P15586,Q9BT22,Q92766,Q15392,Q13510,P28070,O15118,P33991,O60762,Q96A33,P21964,P61916,P16278,O95453,Q6PGP7,Q9NZ08,Q16625,O00203,P83436,P54802,Q10713,P14174 28 +Abnormal esophagus physiology 0.3184781934731174 0.8768299848852816 0.3805789899509739 1.0 0.9491464885026948 221 P00846,Q99720,Q14108,Q96F07,O75306,O14678,P07602,P35670,Q9BQP7,P15586,Q8IZA0,P03886,Q9Y584,Q9HA77,Q8NFF5,O15269,Q92766,Q9UGP8,Q13510,O15118,Q96A33,P21964,Q9NSD9,Q9Y619,P61916,O95453,Q96PU5,O00203,O43791,Q9UHX1,P16435,Q8N3U4,Q9UBB4,Q9BV10,Q9BUF5,Q96RR1,O95202,Q05086,P06280,Q8NC96,P83436,Q9NR77,O43819,P20700,Q9UEY8 45 +Generalized onset seizure 0.3809399655181757 0.8729841462230231 0.3826717190704061 1.0 0.9500354249342596 108 P00846,Q14108,P07602,Q71SY5,P03886,Q9HA77,Q8NHS3,Q13510,Q9NVI7,O60762,Q9Y619,P16278,Q96N66,O75503,P61978,O14653,Q9NUQ7,Q9UBB6,Q9UBB4,Q08J23,Q8TB37 21 +Abnormality of the larynx 0.3819056476232184 0.8704866508299677 0.3840345112514316 1.0 0.9500354249342596 43 P21964,P16435,Q15165,Q96HY6,Q92766,P07602,Q13510,Q9UHX1 8 +Flattened epiphysis 0.6269692004750538 0.8700659388037834 0.3842643704191748 1.0 0.9500354249342596 4 O95831 1 +Mucosal telangiectasiae 0.4976148339072599 0.866201487286177 0.3863796779024857 1.0 0.9500354249342596 9 P06280 1 +Retinal dysplasia 0.5449122038251194 0.8656727669586799 0.3866696384007886 1.0 0.9500354249342596 6 P07437,Q10713,O43505 3 +Abnormal femoral neck head morphology 0.3829207514824101 0.8637359058948388 0.387732984323458 1.0 0.9500354249342596 45 O75844,Q9Y2D4,Q9Y619,Q96HY6,P16278,Q6NUQ1,Q7LGA3,Q9NR45,O95831,O75718,Q96A33,Q9Y487,Q9NUQ7,O75431 14 +Chromosomal breakage induced by crosslinking agents 0.7646606969535892 0.8599602792512481 0.3898109384038823 1.0 0.9500354249342596 3 P13073 1 +Type i diabetes mellitus 0.4728459757453727 0.8586856867211096 0.3905139493465874 1.0 0.9500354249342596 11 P03886,P00403 2 +Chromosome breakage 0.4725356224602353 0.8569988818686025 0.3914455025668095 1.0 0.9500354249342596 11 P33991,P13073 2 +Spastic diplegia 0.4016698168449962 0.8563527040947833 0.3918027171209264 1.0 0.9500354249342596 24 Q99720,P07602 2 +Progressive external ophthalmoplegia 0.4600376286858799 0.8545331592314475 0.3928096447068141 1.0 0.9500354249342596 12 Q9BQP7,P03886,P00403,Q96RR1 4 +Osteolysis involving bones of the upper limbs 0.5294679504156075 0.8543219912854522 0.3929266055465465 1.0 0.9500354249342596 7 O75844 1 +Tetraparesis 0.3708080116440672 0.854234521075063 0.3929750593704753 1.0 0.9500354249342596 34 P00846,P07602,P50336,Q96B26,Q9UBX3,P20700,Q9HA77 7 +Abnormal femoral head morphology 0.4127489263556725 0.853957063303068 0.3931287801111445 1.0 0.9500354249342596 19 P16278,Q6NUQ1,Q7LGA3,O95831,Q9NUQ7,O75431 6 +Distal muscle weakness 0.3918087774212888 0.8534690109882186 0.3933992655516436 1.0 0.9500354249342596 61 P00846,Q99720,P07196,Q9BQT8,Q9NR77,O95831,P41440,Q8IY17 8 +Osteopenia 0.3942151593859251 0.8530801506213364 0.3936148580869747 1.0 0.9500354249342596 70 O75844,Q9NSD9,Q5JRA6,Q14108,Q13277,P07602,P61978,Q13126,P57740,Q9NZJ7,Q32P28,Q9Y487,O75718,O75431,Q9NWM8 15 +Increased muscle fatiguability 0.5703330123502602 0.8516314578328366 0.3944186740317505 1.0 0.9500354249342596 5 P53985 1 +Abnormal circulating protein concentration 0.327243537734662 0.8509810018601396 0.394779906283252 1.0 0.9500354249342596 144 O95470,P07196,P57740,O95831,Q9BQP7,O00400,Q9Y584,Q9Y487,O43505,Q16836,Q13586,Q8NFF5,Q9NWM8,Q8N511,Q9UJS0,Q86VD7,Q9BT22,O60762,Q8WXH0,P53985,Q5XKP0,O95817,O14979,Q9NSD9,O43772,Q8N1F7,P50570,Q6PGP7,Q7Z4W1,P50402,Q6ZXV5,O14653,P50416,P42167,Q9BV10,Q9BUK6,Q96RR1,Q9HC07,P10253,P83436,P23786,Q00059,Q08J23,O75648,P14174,P41440 46 +Abnormal circulating fatty acid concentration 0.408541544723858 0.8508271031097671 0.3948654035762748 1.0 0.9500354249342596 21 O43772,O75381,P35914,P23786,O75648,O75880,O75431 7 +Endocarditis 0.5412917778149573 0.8496814216706745 0.3955022301470472 1.0 0.9500354249342596 6 Q9NZ08 1 +Neurofibrillary tangles 0.7614497412565051 0.8488087404975453 0.3959877257910205 1.0 0.9500354249342596 3 O15118 1 +Abnormality of chorioretinal pigmentation 0.6212697813452946 0.847906635207509 0.3964899690075107 1.0 0.9500354249342596 4 Q5XKP0 1 +Global brain atrophy 0.4117023370128109 0.8466862385658158 0.3971700311669277 1.0 0.9500354249342596 19 O75306,O43819,Q9UHX1,P07602 4 +Bilateral cryptorchidism 0.4705798712333973 0.8463738233791299 0.3973442365785087 1.0 0.9500354249342596 11 P48449,P37268 2 +Abnormal 2nd finger morphology 0.5271035481487335 0.843524650171229 0.3989350855116085 1.0 0.9500354249342596 7 Q9H6K4 1 +Hyperreflexia 0.3211820722024505 0.8391013417000788 0.4014124432634223 1.0 0.9500354249342596 233 P00846,Q99720,O43681,Q96F07,Q9BRK0,P07602,O95831,P50336,O00400,P03886,Q8WWY3,O75027,Q7KZN9,Q9UP83,O14949,Q9BQT8,Q86XL3,Q9BVA1,Q9H6K4,O60762,Q5XKP0,P13073,Q9BXW9,Q9Y619,O75381,Q9NZ08,Q16625,Q96N66,O75503,Q5KU26,O75746,P20674,Q6DKK2,Q10713,Q9UBB4,Q9UNW1,O75298,Q96IX5,Q96CU9,O75787,Q9NR77,Q08J23,O14773,P20700,Q9P0J0,Q8TB37,P49902,Q8IY17 48 +Shallow orbits 0.4798477897027124 0.838373336723986 0.4018210594769082 1.0 0.9500354249342596 10 O75844,O75431 2 +Abnormal enzyme coenzyme activity 0.2998187464342645 0.8382542740823029 0.4018879109530244 1.0 0.9500354249342596 183 P00846,Q6NUQ1,O14678,P07602,P35670,P50336,P03886,Q9NZJ7,O75880,O43505,Q16836,Q8N511,Q9UJS0,P46783,Q9UP83,Q13510,P28070,O15118,O60762,Q96A33,Q5XKP0,O43772,Q9NSD9,P22695,Q9Y619,P61916,P16278,Q16625,P35914,P20674,O75431,P50416,Q9BV10,Q96RR1,Q9HC07,P83436,O75787,P23786,P10619,O75648,Q10713,P41440 42 +Motor polyneuropathy 0.4794875589810333 0.8364979779542199 0.4028748138164195 1.0 0.9500354249342596 10 O43819,P07196 2 +Abnormality of the vasculature of the eye 0.3921274642797049 0.8340288185385978 0.4042647444937635 1.0 0.9500354249342596 69 P00846,P21964,P38435,P16278,P02786,O75306,P06865,Q92766,Q9NZ08,P07602,Q13510,P06280,P10619,Q8WWY3,P28070,P03886,Q96DF8 17 +Skin nodule 0.4061640374949655 0.8337708652229601 0.4044101160315443 1.0 0.9500354249342596 21 P16615,P52732,Q9NZ08,Q13510,P06280,P35637,Q8NBM4,P04114 8 +Malrotation of small bowel 0.6173798961041255 0.832832769437066 0.4049390506013903 1.0 0.9500354249342596 4 Q8NCH0 1 +Abnormal circulating androgen level 0.4450739053901985 0.8283344018372298 0.4074811452726028 1.0 0.9500354249342596 13 Q13423 1 +Papule 0.4115222485853914 0.8281166179502095 0.4076044591712793 1.0 0.9500354249342596 17 O75844,Q9NZ08,P38435 3 +Stroke 0.3751625014517175 0.8267635088584087 0.4083711168183734 1.0 0.9500354249342596 30 O75844,P06280,P03886,P00403 4 +Subcutaneous nodule 0.4121209629455057 0.8266896652742785 0.408412980528738 1.0 0.9500354249342596 16 Q13510,P06280 2 +Left ventricular systolic dysfunction 0.5357831480488744 0.8254080954603806 0.4091399403952962 1.0 0.9500354249342596 6 O75844,Q96RR1 2 +Abnormally lax or hyperextensible skin 0.3768570129067586 0.8244136949777741 0.409704535963975 1.0 0.9503226873177792 43 P07437,O96000,P38435,O95453,Q9BZK7,Q8NCH0,Q9Y487,Q9UHX1,Q9NWM8 9 +Multifocal epileptiform discharges 0.3909394563058049 0.823429206706795 0.41026395977219 1.0 0.9503226873177792 26 Q9UBB6,O75503,Q08J23,Q9UBX3,Q9HA77 5 +Vertebral hypoplasia 0.4769039912445867 0.8230567584763949 0.4104757173650748 1.0 0.9503226873177792 10 Q96HY6,P16278 2 +Absent brainstem auditory responses 0.7536770645395421 0.8219349820455528 0.4111139020452548 1.0 0.9503226873177792 3 P07196 1 +Decreased activity of mitochondrial complex iii 0.4764391086183175 0.8206398659973357 0.4118514327278157 1.0 0.9504453747211158 10 Q9Y584 1 +Motor axonal neuropathy 0.4434428637103713 0.8187010175185787 0.4129570159610485 1.0 0.9518990297123974 13 O95831,O15269,Q8IY17 3 +Hiatus hernia 0.4994039321574033 0.8186439999822317 0.4129895554756515 1.0 0.9518990297123974 8 Q04656,P57740,Q8NCH0 3 +Abnormal peripheral nervous system morphology 0.3128882693119524 0.8160272983800854 0.4144845228226208 1.0 0.9526204405816704 150 P00846,Q99720,O43681,P07196,P07602,P00403,Q9BQP7,O95831,Q9BZK7,Q71SY5,P03886,O15269,Q13510,Q9BQT8,Q9NVI7,Q9Y619,P50570,O75381,Q6DKK2,Q9UHX1,Q9UBB4,Q9BV10,Q9BUF5,Q9NR77,O43819,Q96TA2,P20700,P41440,Q8IY17 29 +Distal lower limb muscle weakness 0.4095086391489729 0.8145701272317313 0.415318415648287 1.0 0.9538348843405856 17 P00846,Q9NR77,Q8IY17 3 +Short femur 0.5325759388442907 0.8113108533147384 0.4171871788500318 1.0 0.955732845194762 6 Q9UHX1,Q9BV10 2 +Neurodegeneration 0.3924523776042912 0.8094927584064245 0.4182317665434367 1.0 0.955732845194762 25 Q8NHS3,Q15165 2 +Shoulder girdle muscle weakness 0.4519508607038889 0.8086855142648509 0.4186960624947731 1.0 0.955732845194762 12 P07602,Q9NZJ7,Q96RR1 3 +Hypoplastic heart 0.5595618979598156 0.8067232801621155 0.4198259285238888 1.0 0.955732845194762 5 O43791 1 +Abnormality of circulating adrenocorticotropin level 0.4969100566971058 0.8066861587385539 0.4198473205160213 1.0 0.955732845194762 8 Q13423 1 +Tinnitus 0.4413127130026191 0.8061308957282937 0.420167378820381 1.0 0.9559810276525996 13 Q9NR77 1 +Cardiorespiratory arrest 0.6101287709825745 0.8048504393669901 0.4209059908883408 1.0 0.9562404213859512 4 O43772 1 +Abnormal circulating albumin concentration 0.3811086985540576 0.8045467504686632 0.4210812810291133 1.0 0.9562404213859512 28 Q8N1F7,Q9NSD9,Q9BT22,Q9BV10,Q6PGP7,O95470,Q5XKP0,Q9UJS0 8 +Muscle weakness 0.3386429672414763 0.8041845504465452 0.4212903999735298 1.0 0.9562404213859512 288 P00846,Q99720,O43681,Q96F07,O75306,P07196,P07602,P00403,P35670,Q9NPL8,Q9BQP7,O95831,Q70HW3,Q8NCH0,P03886,Q9BZK7,Q71SY5,O00400,P50336,O43505,Q13586,Q8NFF5,Q9NWM8,O15269,O43676,P06865,Q13510,Q9BQT8,Q92804,Q53H12,Q5XKP0,P13073,O43772,P50570,Q4J6C6,O75381,P50402,P61978,Q5KU26,O75380,Q96B26,Q6DKK2,Q9UHX1,Q86Y39,O96000,Q10713,Q15165,Q9Y375,Q9BUK6,Q9UNW1,O75298,Q9BUF5,Q96RR1,Q9HC07,Q96CU9,Q8NC96,Q13126,Q9NR77,P23786,O43819,Q9UMS0,Q96TA2,O75648,P20700,Q9P0J0,Q8TB37,P41440,Q8IY17 68 +Nonprogressive 0.5588304131148696 0.8036856611185569 0.4215785372727929 1.0 0.9562404213859512 5 Q10713 1 +Macrogyria 0.5581057083587162 0.8006778233134626 0.4233181842789995 1.0 0.9565767228209744 5 O43505,Q15392 2 +Abnormality of the extraocular muscles 0.7374031007751909 0.7990811813402839 0.4242433408007877 1.0 0.9565767228209744 2 Q9BVA1 1 +Soft skin 0.4839762610694648 0.7980738788850068 0.4248276187421891 1.0 0.9565767228209744 9 Q13126 1 +Abnormality of the autonomic nervous system 0.3829645970313545 0.7975013589131668 0.4251599139387361 1.0 0.9565767228209744 55 P21964,Q8N3U4,O43681,Q96RR1,Q92766,P07602,P06280,P50336,Q9NZJ7,P20700,Q10713,P41440,P42892,O15269,Q9BXW9 15 +Dilatation of the cerebral artery 0.4716452316628435 0.7957492744882495 0.4261777805019116 1.0 0.9569948468520576 10 Q9NSD9 1 +Abnormality of the lymphatic system 0.3234672054110349 0.7928646712093391 0.427856672607134 1.0 0.9569948468520576 144 Q14108,Q96HY6,Q6NUQ1,Q9NRW7,P07602,P31751,P35670,Q9BZK7,P15586,Q13586,Q9UJS0,Q9UP83,Q9BT22,Q92766,Q15392,Q13510,P28070,O15118,P33991,O60762,Q96A33,P21964,P61916,P16278,O95453,Q6PGP7,Q9NZ08,Q16625,O00203,Q9NVR5,Q9UNW1,O95202,P83436,P10619,P54802,Q10713,P14174 37 +Tetany 0.5551739076600541 0.7885264703813857 0.4303888215253173 1.0 0.9569948468520576 5 P21964 1 +Reduced brain n acetyl aspartate level by mrs 0.7431600987789949 0.7858645310910515 0.4319468559934969 1.0 0.9569948468520576 3 P07602 1 +Abnormal brain n acetyl aspartate level by mrs 0.7431600987789949 0.7858645310910515 0.4319468559934969 1.0 0.9569948468520576 3 P07602 1 +Abnormal brain choline level by mrs 0.7431600987789949 0.7858645310910515 0.4319468559934969 1.0 0.9569948468520576 3 P07602 1 +Multifocal cerebral white matter abnormalities 0.5544476899162059 0.7855208133718834 0.4321482720888769 1.0 0.9569948468520576 5 Q9Y619 1 +Photoreceptor layer loss on macular oct 0.7335271317829466 0.7848838325082836 0.4325216820511224 1.0 0.9569948468520576 2 P04439 1 +Abnormal optical coherence tomography 0.7335271317829466 0.7848838325082836 0.4325216820511224 1.0 0.9569948468520576 2 P04439 1 +Laryngeal dystonia 0.6047188106011648 0.784079704473857 0.4329933434334241 1.0 0.9569948468520576 4 O75569,Q96RL7,P02792 3 +Abnormality of lower limb metaphyses 0.5539990962440206 0.7836650479314308 0.4332366765275595 1.0 0.9569948468520576 5 O95831 1 +Sensory neuropathy 0.3649171403302524 0.7810128694489488 0.4347949255691592 1.0 0.9569948468520576 36 P00846,O95831,P03886 3 +Elevated serum acid phosphatase 0.7415639589892755 0.7804214275095229 0.4351428594726028 1.0 0.9569948468520576 3 P07602 1 +Hand muscle weakness 0.4803258592596519 0.7799190747473593 0.435438510092575 1.0 0.95707736570566 9 Q9NR77 1 +Corneal opacity 0.3792568858265673 0.7743194272450729 0.43874191793277 1.0 0.9587558553957783 53 O75844,P52732,P16278,O95202,O75381,Q16625,Q13510,P06280,P35670,P10619,Q9NVI7,Q06136,P04114,P51648,O43505,Q9Y5Z9 16 +Inappropriate crying 0.5114341371431488 0.7723022073756572 0.4399354583495256 1.0 0.9588228849865053 7 P07602,Q9NZJ7 2 +Thoracic kyphosis 0.425525311466271 0.7713418596267065 0.440504326942404 1.0 0.9588228849865053 14 O95831,Q9UHX1 2 +Abnormal corneal epithelium morphology 0.4352677861476364 0.7705358105414164 0.4409821210646771 1.0 0.9588228849865053 13 O75844,Q9NZ08 2 +Recurrent paroxysmal headache 0.4665631266378531 0.7694328775810461 0.4416363772004654 1.0 0.9588228849865053 10 P03886 1 +Ankylosis 0.5503014520855112 0.7683942471573639 0.4422529971196103 1.0 0.9588228849865053 5 O75844 1 +Abnormal aortic valve physiology 0.3656390030151875 0.7678046816388547 0.4426032327312528 1.0 0.9588228849865053 38 O75844,P16278,Q9NZ08,Q96PU5,P04114,Q9UHX1 6 +Skin plaque 0.5498925763115947 0.7667085313338421 0.4432548301233279 1.0 0.9588228849865053 5 Q06136 1 +Elevated urinary dicarboxylic acid level 0.7283591731266065 0.7660596886116866 0.4436407874021446 1.0 0.9588228849865053 2 P50336 1 +Respiratory paralysis 0.7283591731266065 0.7660596886116866 0.4436407874021446 1.0 0.9588228849865053 2 P50336 1 +Porphyrinuria 0.7283591731266065 0.7660596886116866 0.4436407874021446 1.0 0.9588228849865053 2 P50336 1 +Elevated urinary delta aminolevulinic acid 0.7283591731266065 0.7660596886116866 0.4436407874021446 1.0 0.9588228849865053 2 P50336 1 +Abnormal insulin level 0.3914982713131102 0.7600611245933134 0.4472180488153525 1.0 0.9606102469555776 23 O75844,P31751,P53985 3 +Spasticity 0.341628440705177 0.7595454611682673 0.4475263300285723 1.0 0.9606102469555776 306 P00846,Q99720,O43681,Q96F07,Q9BRK0,P07196,P07602,O00584,O95831,Q71SY5,O00400,P03886,Q9Y487,O43505,Q9HA77,Q5BJH7,Q7KZN9,P50897,Q15392,Q13510,Q92804,Q86XL3,Q9NVI7,P49366,O15118,Q9H6K4,Q9UBX3,O60762,Q5XKP0,Q9Y619,P61916,P16278,O75381,Q16625,Q96N66,O75503,P35914,Q5KU26,Q96B26,P51648,O75746,Q9NR50,Q6DKK2,Q9NUQ7,Q10713,Q9UBB6,Q15165,Q8N3U4,Q9UBB4,Q9UNW1,O75298,Q8NC96,O75787,O43819,Q08J23,P11117,P20700,Q9P0J0,Q9UEY8,Q8TB37,P49902,Q8IY17 62 +Abnormal thalamic mri signal intensity 0.507926237463624 0.7564498758151537 0.4493795140672008 1.0 0.9606102469555776 7 Q99496,Q969Y2,Q96RR1,P02792,Q969G3,Q96EY7 6 +Vasculitis 0.5473035491328012 0.7560482630563504 0.4496202596384262 1.0 0.9606102469555776 5 Q9NZ08 1 +Hyperextensible skin 0.4121856141444496 0.7536590847581546 0.4510539560452962 1.0 0.9613779892037077 15 Q9UHX1,Q8NCH0 2 +Abnormal cerebral artery morphology 0.4118078676158387 0.7512686336106497 0.4524910022025641 1.0 0.96279203380818 15 Q9NSD9,P38435 2 +Abnormal glial cell morphology 0.3762930467919573 0.7466237569564977 0.4552907038815883 1.0 0.965122549641364 53 P00846,O43819,O95831,Q9NR50,Q7KZN9 5 +Multifactorial inheritance 0.4520247369114913 0.7460675807022865 0.4556265919453688 1.0 0.9652861143951535 11 Q07812,P42892,P10321 3 +Abnormal pupil morphology 0.4515143286960826 0.7433238233667981 0.4572856515434877 1.0 0.9652861143951535 11 O95202,Q9NR77 2 +Abnormality of the pharynx 0.3713919386277679 0.7425183901284763 0.4577733137989204 1.0 0.9655410477398884 47 Q03518,P21964,Q9BV10,P16278,Q13277,Q92766,O95453,Q13510,Q13432,P54802,Q9NVR5 11 +Orthostatic hypotension 0.4207666417463825 0.7423611923896257 0.4578685256786474 1.0 0.9655410477398884 14 O43681,P07602,P20700 3 +Cataplexy 0.593640078270393 0.7418583047492183 0.4581731904218404 1.0 0.9655410477398884 4 O15118 1 +Irritability 0.3827819292987487 0.735497118524728 0.4620367942173913 1.0 0.968545431654226 73 O43772,P00846,P50897,P37268,P07602,Q13510,O95831,Q5KU26,Q5BJH7 9 +Large for gestational age 0.4709731506375407 0.7335938770345701 0.4631962937952996 1.0 0.9705269245572188 9 Q12955,P31751,P50570 3 +Abnormal posterior segment imaging 0.5912544815627265 0.732826228903126 0.4636644217242827 1.0 0.9710586363435046 4 P04439,Q8WWY3 2 +Rickets 0.540859675082252 0.7296238713573227 0.465620126608766 1.0 0.973354487096313 5 Q9NSD9,O43175 2 +Short chin 0.4374816253526372 0.7271444666076594 0.4671374612791881 1.0 0.9751763592602406 12 O75844 1 +Epistaxis 0.4075372110855718 0.7242866949299067 0.4688897436002601 1.0 0.977933028779548 15 Q9BZK7,P38435 2 +Dyskinesia 0.3804192731761521 0.7209103604525374 0.4709646680663768 1.0 0.9780144521280406 68 P00846,Q9UBB6,Q8NC96,O43819,Q08J23,P03886,Q9UBX3,Q9P0J0,Q5BJH7 9 +Gaze evoked nystagmus 0.4569687625403292 0.7199834576754374 0.4715351807700925 1.0 0.9781712798773128 10 Q10713,P41440 2 +Multiple joint contractures 0.3958117262228619 0.7189894190191719 0.4721474391332918 1.0 0.9788686037866416 16 O75844 1 +Aplasia hypoplasia of the palmar creases 0.7221324717286157 0.7148850742895445 0.4746800605545278 1.0 0.981753285745523 3 Q99567,Q8NCH0 2 +Progressive microcephaly 0.3605541926008803 0.7125454955571011 0.4761270492942187 1.0 0.981753285745523 39 Q9Y487,Q5KU26,P50897 3 +Fetal distress 0.3765210365109687 0.7109341057709591 0.4771250701052891 1.0 0.981753285745523 26 O43676,O96000,Q96CU9,Q9NPL8,Q9NVI7,Q8TB37,P03886,Q9Y375,O75380,Q86Y39 10 +Headache 0.3784004147710069 0.7098306054213598 0.4778091875592218 1.0 0.981753285745523 65 P00846,Q9NSD9,Q9NZ08,P00403,P23786,P03886,Q13586 7 +Sloping forehead 0.3578125609911156 0.7074207513658789 0.479305044935995 1.0 0.981753285745523 37 Q8N3U4,Q9H936,P52732,Q16625,O43175,P08243,P57740,Q86XL3,P23786,Q08J23,Q9BXW9 11 +Muscle fiber tubular inclusions 0.7193878735015964 0.705744848160461 0.4803468253743281 1.0 0.981753285745523 3 Q13586 1 +Hyperintensity of cerebral white matter on mri 0.3879981427005891 0.7041007308194187 0.4813700450396598 1.0 0.981753285745523 21 O43681,Q9BUK6,P54136,P07602,O75503,P10253,Q9NZJ7,Q9H553,P20700 9 +Abnormal size of pituitary gland 0.5077619663648067 0.7033133851144855 0.4818604709625151 1.0 0.981753285745523 6 Q99496,Q14746,P35222,Q93074,Q969G3 5 +Pulmonary embolism 0.7183738062612054 0.7023755337737865 0.4824449990962665 1.0 0.981753285745523 3 Q9NZ08 1 +Pleuritis 0.7183738062612054 0.7023755337737865 0.4824449990962665 1.0 0.981753285745523 3 Q9NZ08 1 +Orchitis 0.7183738062612054 0.7023755337737865 0.4824449990962665 1.0 0.981753285745523 3 Q9NZ08 1 +Neuroinflammation 0.7183738062612054 0.7023755337737865 0.4824449990962665 1.0 0.981753285745523 3 Q9NZ08 1 +Abnormal liver physiology 0.5340379925321556 0.7018309861308764 0.4827845723130157 1.0 0.981753285745523 5 Q13510 1 +Hemivertebrae 0.4436460978312579 0.7011569848378909 0.4832050509865448 1.0 0.981753285745523 11 P16435,Q9UHX1,Q9Y619 3 +Thyroid carcinoma 0.3907089851062635 0.6941881765863651 0.487564206379711 1.0 0.9847643074892573 18 Q9UNW1 1 +Respiratory failure 0.3763954192661983 0.6938696744361588 0.4877639430392184 1.0 0.9847643074892573 64 O75306,P07602,Q9BQP7,Q70HW3,Q9NZJ7,Q9BT22,Q13510,Q92804,P33991,Q5XKP0,Q9NSD9,Q9Y619,P61916,Q96B26,Q9NVR5,Q15165,P23786,O43819,Q9UMS0 19 +Epiretinal membrane 0.7080103359173151 0.6932200518039907 0.4881714663062455 1.0 0.9847643074892573 2 P04439 1 +Retinal perforation 0.7080103359173151 0.6932200518039907 0.4881714663062455 1.0 0.9847643074892573 2 P04439 1 +Central diabetes insipidus 0.7080103359173118 0.6932200518039797 0.4881714663062524 1.0 0.9847643074892573 2 O76024 1 +Retinal fold 0.708010335917311 0.6932200518039755 0.4881714663062551 1.0 0.9847643074892573 2 P52732 1 +Abnormality of the spleen 0.3523185846015368 0.6928738625589078 0.4883887137893812 1.0 0.9847643074892573 121 Q14108,Q96HY6,Q6NUQ1,Q9NRW7,P07602,P35670,P15586,Q13586,Q9UJS0,Q9UP83,Q9BT22,Q92766,Q15392,Q13510,P28070,O15118,P33991,O60762,Q96A33,P21964,P61916,P16278,O95453,Q6PGP7,Q9NZ08,Q16625,O00203,Q9NVR5,O95202,P83436,P10619,P54802,Q10713,P14174 34 +Aplasia hypoplasia of the cerebral white matter 0.4505369265397602 0.6870329722511789 0.4920619507488013 1.0 0.9869383117792072 10 P03886 1 +Chorioretinal coloboma 0.5038086422301216 0.686316454287331 0.4925135751545895 1.0 0.9869383117792072 6 O60826,Q10713,O60315 3 +Congenital malformation of the left heart 0.5037004865282857 0.6858523824353386 0.4928062002119162 1.0 0.9869383117792072 6 O43791 1 +Emg impaired neuromuscular transmission 0.5781683676888041 0.6836966675545366 0.4941667282249204 1.0 0.9869383117792072 4 O60313,Q9H553 2 +Agitation 0.3623735124197823 0.6836465320213199 0.4941983939611938 1.0 0.9869383117792072 29 Q15165,P52732,P48449,Q92804,P42892 5 +Hepatic encephalopathy 0.5768197448219519 0.6786760287421064 0.4973431579657172 1.0 0.9869383117792072 4 Q9UJS0 1 +Slowly progressive 0.3722850744173251 0.6757881658712038 0.4991751493071654 1.0 0.9869383117792072 59 Q99720,Q9BRK0,P07196,P50402,O00584,Q9NR77,O95831,Q9P0J0,Q13586,O14773,P41440 11 +Aplasia of the uterus 0.4693240327238078 0.6757100876620978 0.4992247299856542 1.0 0.9869383117792072 8 Q9UNW1 1 +Delayed closure of the anterior fontanelle 0.4096794548920235 0.6752326541212894 0.4995279633912375 1.0 0.9869383117792072 14 Q9Y487 1 +Delayed puberty 0.3671749468250544 0.6748752788000988 0.4997550079438033 1.0 0.9869383117792072 51 O75844,Q14108,P06280,Q15800,Q8IY17,Q9UJS0 6 +Abnormality of the intrinsic pathway 0.4478925038198156 0.6735382508002719 0.5006049224343254 1.0 0.9869383117792072 10 Q9Y487,P38435,O60762 3 +Wide anterior fontanel 0.3817872809507156 0.673118772305404 0.5008717320254084 1.0 0.9869383117792072 22 P16435,O75381,Q08J23,O75718,Q9Y487,P20674 6 +Metaphyseal widening 0.3864951219870738 0.6727686156920116 0.5010945070843658 1.0 0.9869383117792072 19 Q9NR45,O95831,Q96HY6,P16278 4 +Decreased cd4 cd8 ratio 0.5747546163984535 0.6710043337606425 0.5022177687208842 1.0 0.9882691112661046 4 Q13432 1 +Central nervous system cyst 0.367430136601413 0.670538750028845 0.502514412899032 1.0 0.9882691112661046 52 P00846,O95202,P23786,Q9Y487,Q9UHX1 5 +Developmental regression 0.3562350850579732 0.6703372398516488 0.5026428327499128 1.0 0.9882691112661046 116 P00846,O43681,P16278,Q9NZ08,P07602,O75503,P06280,Q13510,Q8NC96,O95831,O43819,P03886,Q9NR50,Q9HA77,O14773,P13073 16 +Abnormal renal physiology 0.3017814493316595 0.6680824960322211 0.5040809344321067 1.0 0.988522351938287 151 Q14108,O75306,O95470,P00403,P35670,Q9NPL8,Q9BZK7,P50336,Q8NCH0,P03886,O43676,Q9BT22,Q03252,Q9BXW9,O43772,Q8N1F7,Q13277,Q9NZ08,P09601,Q16625,O75380,P50416,Q86Y39,O96000,Q96CU9,P06280,P23786,O43819,Q9Y375,Q10713,Q8TB37,Q8IY17 32 +Abnormality of skeletal muscle fiber size 0.386745437120432 0.6674878791048258 0.5044605493972929 1.0 0.988838722963971 18 O95831,Q13586,Q9BUK6,Q96RR1 4 +Aplasia hypoplasia of the earlobes 0.4669143456136127 0.6644084300867178 0.5064289387992718 1.0 0.9897102218841434 8 P98175,P21964,Q92766 3 +Poor head control 0.3758104390579053 0.6637807447908407 0.5068306513348899 1.0 0.9897102218841434 75 Q96F07,Q9H936,O75306,P07602,Q9NPL8,P03886,Q9NZJ7,Q9NWM8,O43676,Q9Y6M9,P06865,P54136,Q9NQT5,Q5XKP0,P13073,Q5KU26,O75380,Q9P0J0,Q86Y39,O96000,Q96CU9,Q8NC96,Q9H553,Q9Y375,Q10713,Q8TB37,P00374 27 +Retinal dystrophy 0.3666280430705113 0.6631091584678239 0.5072606454811015 1.0 0.9897102218841434 52 Q10713,P00846,P38435,P52732,Q9NVR5,Q8NHS3,O75381,P36404,Q8WWY3,Q6P4Q7,P03886,P04114,Q9NQT5,O43505,Q13868,Q8IY17 16 +Hypokinesia 0.4259253232197451 0.662632434535293 0.5075659920311231 1.0 0.9897102218841434 12 O95831,Q96RR1 2 +Hyporeflexia 0.3566206068882383 0.6621219623776411 0.5078930616210513 1.0 0.9897102218841434 115 P00846,Q99720,O43681,Q96F07,P07196,P07602,Q9BQP7,O95831,Q71SY5,P50336,P03886,O43505,Q13586,O15269,P50570,O95453,P35914,Q9UBB4,Q9BUK6,Q96RR1,P83436,Q8NC96,O75787,Q9NR77,P54802,Q10713,P41440,Q8IY17 28 +Hepatosplenomegaly 0.3513510857255175 0.6599415867205854 0.5092913154792909 1.0 0.989742453505443 36 Q9UP83,Q96HY6,P16278,Q13510,O00203,O60762,Q9UJS0 7 +Connective tissue nevi 0.6983204134366923 0.6593269967625224 0.5096858099994641 1.0 0.9900843564740875 2 Q6NUK1 1 +Recurrent pneumonia 0.3810377367659338 0.6548486354532427 0.5125652135546392 1.0 0.9916869745145804 21 P78318,Q13432,O00203,Q71SY5,P20700 5 +Breech presentation 0.4641214496744354 0.6513433147530875 0.5148248935123312 1.0 0.9916869745145804 8 O60313,Q9Y619,O75718 3 +Megaloblastic anemia 0.4641194300616381 0.6513338805684292 0.5148309821686576 1.0 0.9916869745145804 8 P00374,P41440,O43175 3 +Exaggerated startle response 0.4956103274890694 0.6512887704765339 0.5148600959432097 1.0 0.9916869745145804 6 P16278 1 +Complete duplication of phalanx of hand 0.5213900202615664 0.6508518896748416 0.5151421003642613 1.0 0.9916869745145804 5 P34897,Q56NI9,Q9BXW9 3 +Talipes calcaneovalgus 0.4951645492297309 0.6493932024986627 0.5160842565371757 1.0 0.9917170687754256 6 Q9NR77 1 +Cupped ear 0.3952973181893766 0.6474755874139644 0.5173241894143401 1.0 0.9919045202947344 15 P42892 1 +Abnormal tissue metabolite concentration 0.4048628125580276 0.6462743182210451 0.5181017168634177 1.0 0.9919045202947344 14 P06865,O43681,P07602,P06280 4 +Severe short stature 0.3758451987585991 0.6451767711035729 0.5188126376087112 1.0 0.9919045202947344 23 Q9Y619,Q96HY6,P16278,Q15392,P10619,Q8IY17 6 +Lateral clavicle hook 0.7008830336245935 0.644963674416622 0.5189507263929265 1.0 0.9919045202947344 3 Q9Y619 1 +Hyperhomocystinemia 0.5673006155013421 0.6434845844040168 0.5199097143824858 1.0 0.9919045202947344 4 P41440 1 +Neoplasm of the thyroid gland 0.3676337658095237 0.6421479835264956 0.5207771031032526 1.0 0.9919045202947344 26 P42892,Q9UNW1 2 +Abnormality of the tonsils 0.4619523887076331 0.6412225899885206 0.5213780747257277 1.0 0.9919045202947344 8 P21964,P31751 2 +Exercise induced muscle cramps 0.4927755162459999 0.6392511169078634 0.5226595832999021 1.0 0.9919045202947344 6 P53985 1 +Aortic regurgitation 0.3749785825836971 0.6388613325836113 0.5229131446448938 1.0 0.9919045202947344 23 O75844,Q96PU5,Q9UHX1,Q9NZ08 4 +Cirrhosis 0.3489142476179903 0.6383245953384362 0.5232624047134664 1.0 0.9919045202947344 36 Q9NSD9,Q14108,O95453,P22830,Q10713,Q9UJS0 6 +Abnormality of pancreas physiology 0.3563352842441291 0.6381844467007101 0.5233536204824376 1.0 0.9919045202947344 43 Q9NZ08,P09601,P00403,P35914,P03886,P53985,P14174,Q9UHX1 8 +Acne 0.412508133604922 0.6378815653735368 0.5235507787226252 1.0 0.9919045202947344 13 P21964,Q9NZ08 2 +Abnormality of bone mineral density 0.3360177141961843 0.6347330815990077 0.5256025139595113 1.0 0.9927611467077369 130 Q14108,Q96HY6,P07602,P35670,P57740,O95831,Q9Y487,Q9NWM8,Q15392,Q13510,Q32P28,Q9BXW9,Q9NSD9,Q5JRA6,P16278,Q13277,O95453,P61978,Q9NUQ7,O75431,O75844,Q96RR1,O95202,Q9HC07,P06280,Q13126,P54802,O75718,Q9Y375 29 +Spina bifida occulta 0.3824538520029596 0.631773505695088 0.5275348884335633 1.0 0.9927973338104444 16 Q9UHX1 1 +Proximal muscle weakness 0.3695147998404409 0.6315422258175455 0.5276860488123827 1.0 0.9927973338104444 63 P00846,Q99720,P50570,Q9BUK6,Q96RR1,P07196,Q13510,Q9BQT8,P35670,P50402,P10253,Q13126,P50336,O60313,Q8WXH0,Q13586,Q8NFF5 17 +Abnormality of extrapyramidal motor function 0.3717266756246105 0.6308729172616152 0.5281236212703817 1.0 0.9927973338104444 70 P61457,Q99720,O96008,P07602,P08243,Q9NZJ7,O14949,P06865,P54136,O43464,Q9H6K4,P16278,Q9H9P8,Q6DKK2,P98175,Q9UBB4,Q96RR1,Q96IX5,O75787,P35637,P11802,Q9Y4P3 22 +Decreased calvarial ossification 0.5638550308898085 0.6308583039815117 0.5281331770259421 1.0 0.9927973338104444 4 O75844 1 +Wide nasal ridge 0.5154294057091477 0.6271029151065012 0.5305917764067136 1.0 0.9927973338104444 5 Q9BZK7 1 +Abnormal intestine morphology 0.2872623566462092 0.6268152656543624 0.5307803356703555 1.0 0.9927973338104444 181 Q9UJW0,P00403,P50336,Q8NCH0,P03886,P46783,Q9BT22,Q92766,Q15392,Q96A33,Q14145,Q9BXW9,P21964,Q9NSD9,Q13277,O95453,O75381,Q9NZ08,P09601,Q6PGP7,P61978,P08183,Q9NVR5,P42892,O75844,Q8N3U4,Q9BV10,Q9UNW1,O95202,P06280,Q08J23,Q10713,P14174 33 +Emg neuropathic changes 0.3684336656907402 0.6264576238988767 0.5310148235333374 1.0 0.9927973338104444 25 O43681,P07602,Q13510,O43819,Q9NR77 5 +Hypertriglyceridemia 0.3709449699178856 0.6261027268147692 0.5312475637912102 1.0 0.9927973338104444 24 P22830,P50402,P31751,P28070,O75431,Q9UJS0 6 +Deformed tarsal bones 0.6946688206785219 0.624908025781478 0.5320314245296116 1.0 0.9927973338104444 3 O43175,O75787 2 +Abnormal circulating proline concentration 0.6940401339787547 0.6228896524158748 0.5333570383136708 1.0 0.9927973338104444 3 P20674 1 +Contractures of the joints of the upper limbs 0.3710693795550849 0.618723831981987 0.5360983072715748 1.0 0.994075043774144 73 O75844,Q9Y2D4,Q99720,Q9Y619,Q9UP83,P16435,Q7LGA3,P37268,P07196,Q15392,P50402,O43175,P23786,P57740,Q9NR77,Q71SY5,Q8IZA0,P42892 18 +Abnormal circulating porphyrin concentration 0.5588897200349536 0.6127740207566289 0.5400257709914762 1.0 0.9956519098866043 4 P22830 1 +Respiratory insufficiency 0.2849907492275904 0.6108191009073553 0.5413193466685302 1.0 0.9969906423590812 178 Q9Y2D4,O75306,P07602,Q9NPL8,Q9BQP7,O95831,Q70HW3,P03886,Q9NZJ7,Q03001,Q13586,Q8NFF5,O43676,Q9BT22,Q9UGP8,O75208,O43464,Q13510,Q92804,Q9NQT5,Q8WXH0,P33991,Q53H12,Q5XKP0,O43772,Q9NSD9,Q9Y619,P61916,P50570,O75381,P50402,O43791,Q96B26,Q9NVR5,Q86Y39,O96000,Q15165,Q9Y375,Q96RR1,Q96CU9,P06280,P83436,P23786,Q9NR77,O43819,Q08J23,Q9UMS0,O75648,O75380,Q8TB37 50 +Abnormality of the antitragus 0.5574429055505842 0.6075300160849512 0.5434992290003464 1.0 0.9985505856783072 4 Q8IY17 1 +Inability to walk 0.3697410703077755 0.6064847102570418 0.5441929323568975 1.0 0.9992679301081256 85 P00846,Q99720,Q8N3U4,O14949,Q9BUK6,Q96RR1,P07196,Q13510,O75503,O75787,Q96N66,Q9NR77,Q9NVI7,Q71SY5,P61978,O15269 16 +Abnormal joint morphology 0.3194020083663249 0.6054084291939076 0.5449076516809368 1.0 1.0 263 Q9Y2D4,Q14108,Q96HY6,Q6NUQ1,P07196,P07602,P35670,P57740,O95831,Q8IZA0,Q8NCH0,Q71SY5,Q9NZJ7,Q9Y584,Q9Y487,O15269,Q9UP83,Q7LGA3,P37268,P51571,Q15392,Q13510,Q92766,O43175,P10321,Q86XL3,P28070,Q9NQT5,Q8WXH0,Q9H6K4,Q96A33,O60762,Q03252,Q9BXW9,O95817,P21964,Q9Y619,Q5JRA6,P16278,Q9NR45,Q9NZ08,P50402,Q96PU5,O00203,Q9UHX1,P42892,O75431,Q9NUQ7,O75844,P16435,Q8N3U4,P38435,Q9BV10,O75298,O95202,Q05086,P06280,O75787,P23786,Q9NR77,O75718,P14174,P49902 63 +Lower limb muscle weakness 0.3515503466975785 0.6040554033547016 0.5458068080710226 1.0 1.0 42 P00846,O75298,Q13510,O43819,Q9NR77,Q8IY17 6 +Metaphyseal irregularity 0.433650021725522 0.6014720895472647 0.547525596085253 1.0 1.0 10 Q9NR45,Q96HY6 2 +Knee flexion contracture 0.3558869200863083 0.600868388803842 0.5479276492886691 1.0 1.0 28 O95817,Q7LGA3,P37268,P23786,Q86XL3,O60762,Q9H553,P49902 8 +Motor seizure 0.3602258743602912 0.6003097643221316 0.5482998125003222 1.0 1.0 105 P00846,P16278,Q8NHS3,P07602,O75503,Q13510,Q5XKP0,O14653,Q08J23,P03886,Q9UBX3,Q9HA77,P13073 13 +Weight loss 0.3680872211749836 0.5976810750128954 0.550052755460156 1.0 1.0 69 O75844,Q99720,Q9NZ08,P07602,P35914,Q06136,P42892,Q13423 8 +Hypercholesterolemia 0.396702079171238 0.597551472269973 0.5501392524825248 1.0 1.0 14 O75431,Q8N511,P04114,Q9UJS0 4 +Cerebellar atrophy 0.3205919979857951 0.5899672117814744 0.5552126318068245 1.0 1.0 138 Q14108,Q96F07,Q9BQP7,O00400,Q9HA77,Q5BJH7,Q9UP83,Q9BT22,Q8NHS3,Q9NVI7,Q9BVA1,Q9H6K4,O60762,Q5XKP0,P13073,P07437,O75503,P51572,Q6DKK2,Q9UBB4,Q96RR1,Q96CU9,P83436,O75787,P46977,Q10713,O14773,P41440,Q8IY17 29 +Abdominal distention 0.3730772538456329 0.5891823815192949 0.5557389346939605 1.0 1.0 20 O43681,Q96HY6,Q13277,Q9UGP8,P07602,O75648 6 +Aplasia hypoplasia involving the nose 0.3577016086426802 0.5890503158103894 0.555827521169902 1.0 1.0 27 O75844,P61978,Q08J23,Q5KU26,Q96DF8,O75431 6 +Joint contracture of the hand 0.3544895699871964 0.5882605654230809 0.5563574103797064 1.0 1.0 47 O75844,P16435,Q9Y619,P07196,Q15392,Q9NR77,Q71SY5,Q8IZA0,P42892 9 +Abnormality of the phalanges of the toes 0.3752741815842374 0.5871612620751302 0.5570954064453164 1.0 1.0 17 O75844,Q7LGA3,Q71SY5,O75431,Q9BXW9 5 +Metatarsus adductus 0.4220353871546386 0.5869041888618064 0.5572680563473205 1.0 1.0 11 O95202,Q08J23,Q15392 3 +Abnormality of the synovia 0.3681733514593801 0.5851476222792232 0.5584484600257569 1.0 1.0 80 O75844,P16435,Q8N3U4,P16278,Q6NUQ1,O95202,Q9NR45,O00203,O75718,Q9Y584,Q9Y487,Q9NUQ7,Q03252,Q9UHX1,Q96A33,Q9BXW9 16 +Cough 0.3571130202970709 0.584457516078158 0.5589125401004813 1.0 1.0 27 Q9NSD9,O95453,Q9NR77,Q9BZK7,P41440,O15269 6 +Abnormal coronary artery morphology 0.4797086140356769 0.5843144799437161 0.5590087519413647 1.0 1.0 6 P16278 1 +Premature graying of hair 0.4494344194648603 0.5833044698731032 0.5596883540200825 1.0 1.0 8 Q13126 1 +Spastic tetraparesis 0.3648899306455643 0.5814253726738313 0.5609538011823956 1.0 1.0 24 P00846 1 +Bradycardia 0.4110681360249113 0.580780364630492 0.5613884903206445 1.0 1.0 12 O43772,Q96RR1,O75208,Q03001,O75880 5 +Gastrostomy tube feeding in infancy 0.3399399385502927 0.5802582210531495 0.5617404969178861 1.0 1.0 34 Q8N3U4,Q99720,Q9UP83,P37268,O43791,O60762 6 +Long eyelashes 0.3455668847922006 0.5787708684157101 0.5627437901473087 1.0 1.0 39 Q9Y619,Q5KU26,P20674,Q9UHX1,Q8IY17 5 +Skeletal muscle atrophy 0.2860268831134709 0.5778347990149826 0.5633756585564729 1.0 1.0 156 Q99720,P07196,Q9NPL8,Q9BQP7,O95831,Q71SY5,O00400,O43505,Q13586,Q9NWM8,O15269,Q13510,Q9BQT8,Q92804,Q9NVI7,Q9BVA1,Q03252,P16278,P50570,P50402,Q6DKK2,P50416,Q15165,Q9BUK6,Q9UNW1,O75298,Q6P4A7,Q13126,Q9NR77,O43819,Q8IY17 31 +Hypoplasia of the iris 0.5028727291421449 0.5777271814835496 0.5634483247873265 1.0 1.0 5 O95202,Q13586 2 +Emotional lability 0.3577286502213682 0.5743238024751577 0.5657487049681025 1.0 1.0 53 Q15165,O43681,P07602,Q9NR50,Q9P0J0 5 +Anencephaly 0.4012979034636526 0.5736340683847152 0.5662154526761918 1.0 1.0 13 O43505,P21964,Q92766 3 +Nausea and vomiting 0.3091402512187776 0.5720415007338407 0.5672938592975421 1.0 1.0 144 P00846,O75306,P07602,P00403,Q9NPL8,Q9BQP7,Q8IZA0,P50336,P03886,Q9NZJ7,Q9Y584,Q16836,Q9UJS0,O43676,P51571,O43464,Q92804,Q13423,Q9NSD9,P22695,Q9Y619,Q13277,Q9NZ08,P35914,P61978,O75380,P42892,Q86Y39,O96000,Q8N3U4,Q15165,Q96CU9,P06280,P23786,O75648,P11117,Q9Y375,Q8TB37 38 +Abnormality of fontanelles 0.3518017636047472 0.5720089691381596 0.5673158983062101 1.0 1.0 46 O75844,P16435,Q9Y619,Q9BT22,O75381,Q08J23,Q8NCH0,Q9Y487,P20674 9 +Spinal deformities 0.6778675282714013 0.5716806296492544 0.5675383596848289 1.0 1.0 3 Q9BQP7,Q8TB36 2 +Aganglionic megacolon 0.3685470350532088 0.5673409491591213 0.5704825609797406 1.0 1.0 21 P21964,Q92766,P42892,Q10713 4 +Abnormal erythrocyte sedimentation rate 0.5456927904702659 0.5653931110417677 0.571806409226082 1.0 1.0 4 P14174 1 +Absent septum pellucidum 0.343678356766793 0.5616062513666894 0.5743843202442185 1.0 1.0 30 Q9UBB6,Q8N3U4,O95202,P51571,Q15392,Q96N66,Q71SY5,Q08J23,O43505,Q9NUQ7 10 +Adipose tissue loss 0.4442580925070833 0.5596250003241581 0.575735248671615 1.0 1.0 8 O75844,O75431 2 +Abnormality of hair pigmentation 0.3658292783503113 0.5593240596014724 0.5759405781869777 1.0 1.0 22 O95453,P37268,Q6PGP7,Q13126,O00203 5 +Goiter 0.4348790091165699 0.558403533375164 0.576568860584642 1.0 1.0 9 Q9UNW1 1 +Abnormal ovarian physiology 0.368395324017944 0.5571607608612762 0.577417596600178 1.0 1.0 20 Q9NR50 1 +Retinal detachment 0.3898277745047405 0.5568923579254199 0.5776009762686507 1.0 1.0 14 O43505,Q8NCH0,Q9BV10,P52732 4 +Facial capillary hemangioma 0.6726978998384522 0.5556168207379248 0.5784728300333823 1.0 1.0 3 P16435,Q56NI9 2 +Abnormal motor nerve conduction velocity 0.3691219517411019 0.5550940740169134 0.578830315914769 1.0 1.0 19 Q9NR77,Q99720,P07196 3 +Abdominal pain 0.3649653264050374 0.5541670231586068 0.579464544559144 1.0 1.0 76 Q14108,Q9NZ08,P06280,P23786,Q9BZK7,Q70HW3,P14174,P42892,Q13423 9 +Neoplasm of the tongue 0.4966052376333689 0.5534460728083528 0.579957997777437 1.0 1.0 5 P08754,Q99496,Q969G3,Q12824 4 +Heart block 0.3675320389151818 0.5512790046311368 0.5814424287389501 1.0 1.0 20 O43772,P23786,P04899,P06280 4 +Meningitis 0.4714044041289047 0.5499233656564897 0.5823719372387641 1.0 1.0 6 Q9NZ08,P02786 2 +Large placenta 0.6704094430137373 0.5485557453943471 0.5833103632557122 1.0 1.0 3 O75844 1 +Abnormal renal echogenicity 0.6647286821705449 0.5465076387836839 0.5847170383208815 1.0 1.0 2 Q9Y2V7 1 +Increased circulating lactate dehydrogenase concentration 0.4044671672574872 0.5449007963735217 0.5858217485258206 1.0 1.0 12 P23786,P41440 2 +Difficulty walking 0.3640759817323665 0.5444052004119004 0.5861626679637912 1.0 1.0 77 P00846,Q99720,O43681,Q9BUK6,O75298,P07602,Q13510,Q8NC96,Q9NR77,Q71SY5,Q8TB37,O14653,O14773 13 +Abnormality of acid base homeostasis 0.2831341500412849 0.5432378388846565 0.5869660569887147 1.0 1.0 182 P00846,Q9BWD1,O75306,P00403,Q9NPL8,O95831,Q70HW3,P03886,Q9Y584,O75880,Q9HA77,Q7KZN9,Q9UJS0,O43676,Q86VD7,O14949,Q9NVI7,Q9UBX3,P53985,Q53H12,Q5XKP0,P13073,P22695,Q9Y619,Q13277,Q4J6C6,P35914,O75380,P20674,P50416,Q86Y39,O96000,Q10713,Q96RR1,Q6P4A7,Q96CU9,P23786,O43819,Q9UMS0,O75648,Q9Y375,Q9P0J0,Q8TB37 43 +Abnormality of the menstrual cycle 0.3526040002961666 0.5410898847137757 0.5884456299786116 1.0 1.0 51 O75844,P16435,Q9BUK6,Q96RR1,P31751,P35670,Q9BZK7,Q9NR50,Q16740,Q9UJS0 10 +Abnormal ilium morphology 0.3669877664450482 0.5408188656272815 0.5886324381138643 1.0 1.0 19 O95831,P16278 2 +Arterial rupture 0.6676943867280194 0.540219088222352 0.5890459502439289 1.0 1.0 3 Q9NWM8 1 +Abnormal aortic arch morphology 0.3953150067814343 0.5397312714432416 0.5893823707641221 1.0 1.0 13 P21964,Q9UHX1,Q96DF8 3 +Diarrhea 0.361879781341089 0.5372756154613365 0.5910772464858192 1.0 1.0 69 P02786,P00403,Q9BQP7,P15586,P03886,Q16836,Q9UJS0,Q9BT22,Q13510,O60762,Q96A33,Q13423,Q13277,Q6PGP7,P35914,P42892,P50416,P06280,P54802,Q08J23 20 +Hemoptysis 0.5367262041466972 0.533818033603555 0.5934674357460028 1.0 1.0 4 Q9NZ08 1 +Abnormality of the coagulation cascade 0.3425211567991217 0.5328381146242732 0.5941456471844575 1.0 1.0 41 Q9Y619,P38435,Q9BV10,Q6NUQ1,Q4KMQ2,P35914,Q9BZK7,O75648,O60762,Q9Y487,Q16836,Q5XKP0,Q9UJS0 13 +Abnormal lymphocyte morphology 0.3331836604499196 0.5322237243493458 0.594571053351252 1.0 1.0 33 P16278,Q6PGP7,O95470,O75787,Q13432,P28070,O00203,P33991,Q03252 9 +Cerebral hypoplasia 0.4113799292085063 0.5316596012379967 0.5949617768641646 1.0 1.0 11 Q86XL3,O60762 2 +Dilated third ventricle 0.4907076827562718 0.5308399678787991 0.5955296809706205 1.0 1.0 5 Q71SY5 1 +Facial diplegia 0.4192993435558335 0.5301216912614871 0.5960275606461218 1.0 1.0 10 O43819,Q96TA2 2 +Duplication involving bones of the feet 0.3850819752845371 0.5290559423281285 0.5967666431155305 1.0 1.0 14 Q10713,P21964,O95202 3 +Lower limb spasticity 0.3612114542064411 0.5283107789760462 0.597283651474013 1.0 1.0 90 P00846,Q99720,O75298,P07602,O95831,Q9H6K4,Q9P0J0,Q6DKK2,Q5XKP0,P49902,Q7KZN9,Q8IY17 12 +Spastic tetraplegia 0.3413551177945048 0.522535159566743 0.6012977728999283 1.0 1.0 41 Q86XL3,O43681,P16278 3 +Abnormality of alkaline phosphatase level 0.362859287050798 0.5195745869197629 0.6033601144298091 1.0 1.0 20 Q8N511,Q9UJS0 2 +Generalized amyotrophy 0.3512227268327733 0.5168608119168797 0.6052533253487469 1.0 1.0 26 O95817,P49589,Q9BQP7,O43819,Q99567,Q03252,Q8IY17 7 +Diabetes insipidus 0.4259727287738838 0.5163721020654584 0.6055945466761607 1.0 1.0 9 Q8N3U4,P06280,Q9H267,O76024 4 +Cerebral white matter atrophy 0.3596632085156622 0.515976923343694 0.6058705267595648 1.0 1.0 22 Q9UP83,O75503,P51572,O43175,P20700 5 +Secondary microcephaly 0.360406140405269 0.515362106249557 0.6063000070828117 1.0 1.0 72 Q9H936,Q9Y487,Q9HA77,P50897,Q9BT22,O75208,O43464,O60762,Q9NQT5,Q5XKP0,Q5KU26,Q9NR50,Q9UHX1,Q86Y39,Q9BV10,Q96CU9,Q9HC07,Q05086,P83436,P00374 20 +Abnormal echocardiogram 0.5313599341061377 0.5151807527643786 0.6064267175131217 1.0 1.0 4 Q96RR1 1 +Recurrent sinusitis 0.4864672847976381 0.5147392827868241 0.6067352190262598 1.0 1.0 5 Q13432 1 +Dental crowding 0.3555761653027895 0.5133954544252478 0.6076747246155274 1.0 1.0 24 O75844,O75431 2 +Proximal amyotrophy 0.3823599826218068 0.5131843111165479 0.6078223994046477 1.0 1.0 14 P07196,P50402,Q9BQP7,Q8WXH0,Q13586 5 +Foot dorsiflexor weakness 0.3413931459569748 0.5126591326941712 0.6081897814674071 1.0 1.0 29 O43819,Q99720,Q9BQT8,Q9NR77 4 +Bifid tongue 0.6581583198707595 0.5113000647235036 0.609140959702823 1.0 1.0 3 P61978,Q9UBM7 2 +Echolalia 0.4247845515738253 0.5108097176981453 0.6094843039034938 1.0 1.0 9 Q9UHX1,Q9UJS0 2 +Temporal optic disc pallor 0.6534237726098058 0.5103986764829368 0.6097721839271717 1.0 1.0 2 O60313 1 +Morning glory anomaly 0.6534237726098058 0.5103986764829368 0.6097721839271717 1.0 1.0 2 O60313 1 +Somatic sensory dysfunction 0.3554421870771545 0.5097574907506888 0.6102213703413106 1.0 1.0 100 P00846,Q9BRK0,P07196,P07602,O95831,Q71SY5,Q8NCH0,P50336,O00400,O15269,Q9H6K4,Q9Y619,P50570,Q9NZ08,P61978,Q9BUK6,O75298,P06280,Q9NR77,P54802,O43819,P20700,O14773,P41440 24 +Cns hypomyelination 0.3388017306520209 0.5094705042923258 0.610422467961516 1.0 1.0 40 Q99720,P51572,O75746,Q9NR50,Q5BJH7 5 +Paranoia 0.4847974467541506 0.5084355692227257 0.6111479134888103 1.0 1.0 5 Q96DF8,P50336,Q96RL7 3 +Decreased circulating cortisol level 0.4239690654637092 0.506998516720384 0.6121558593188179 1.0 1.0 9 Q13423 1 +Leukodystrophy 0.3533845528266198 0.5037018461205032 0.6144709108738629 1.0 1.0 58 O43676,O96000,O43681,Q9Y375,O75306,Q96CU9,P07602,Q9NPL8,O43819,Q8TB37,P03886,P20700,Q9P0J0,O75380,Q86Y39,Q7KZN9 16 +Abnormal brainstem morphology 0.3592329770049198 0.5022777428454285 0.6154721632099271 1.0 1.0 88 O75306,Q9NPL8,P08243,O95831,P03886,O43505,O43676,Q9Y6M9,Q9Y320,Q9UP83,Q9BVA1,O60762,P07437,Q6ZXV5,O60313,Q5KU26,O75380,Q86Y39,Q9Y3B2,O96000,Q8N3U4,Q9Y375,Q9UNW1,Q96RR1,Q96CU9,O43819,P20700,Q10713,Q8TB37 29 +Abnormal spermatogenesis 0.3964742354168074 0.5019329794016848 0.6157146657678265 1.0 1.0 12 P16435,Q13423 2 +Increased blood pressure 0.3575058043245681 0.5014519832246606 0.6160530629461258 1.0 1.0 67 O75844,P21964,Q9NSD9,P16435,P00403,P06280,P50336,Q9UMS0,P03886,P04114,Q10713,P42892 12 +Arterial thrombosis 0.4827010100529755 0.5005515074814587 0.6166867976855723 1.0 1.0 5 Q9NZ08 1 +Moderately reduced visual acuity 0.6536348949919124 0.4977867068663821 0.6186343863626518 1.0 1.0 3 P63000,O60313 2 +Insulin resistance 0.3610105101814641 0.4970955626339609 0.6191216636419568 1.0 1.0 18 O75844,P31751 2 +Hyperconvex nail 0.4302125974143586 0.4963017475706158 0.6196815335037138 1.0 1.0 8 O95202,P42892 2 +Type ii transferrin isoform profile 0.5250481226097026 0.4935235796454915 0.6216426830861317 1.0 1.0 4 Q9UP83,O75787 2 +Vitreous floaters 0.6513731825525052 0.4910810979361599 0.6233690899287672 1.0 1.0 3 P35222,P04439 2 +Proximal muscle weakness in upper limbs 0.3941338640242878 0.4894606856265147 0.6245155814404053 1.0 1.0 12 P07196,P50336,P50402,P50570 4 +Abnormal gallbladder morphology 0.334671434826793 0.4874003941344398 0.6259746142986173 1.0 1.0 30 P21964,O43681,P22830,P07602,Q71SY5,Q96A33 6 +Giant platelets 0.6456718346253256 0.486244677174552 0.6267936983366638 1.0 1.0 2 P35579 1 +Congenital hepatic fibrosis 0.4788620699894927 0.4862034018865378 0.6268229596332358 1.0 1.0 5 Q8IY17 1 +Lipodystrophy 0.3290794949859986 0.4858635283550979 0.6270639285529014 1.0 1.0 34 O75844,P50402,P31751,P28070,Q9Y487,O75431 6 +Abnormality of the fetal cardiovascular system 0.5224809851368882 0.4848001386416684 0.6278181243746059 1.0 1.0 4 O60826,P16435 2 +Scapular winging 0.3576414168367818 0.4844569921092156 0.6280615797797524 1.0 1.0 20 P07196,P50402,O60313,Q8WXH0,Q9Y487 5 +Elevated hepatic transaminase 0.3525416744597281 0.483324316585497 0.6288654769448669 1.0 1.0 101 Q6NUQ1,P35670,P50336,O75880,Q9UJS0,Q8N511,Q9UP83,Q13510,P28070,O60762,Q5XKP0,O43772,Q9NSD9,P22695,Q9Y619,Q16625,P35914,P20674,P50416,O75431,Q9BV10,Q96RR1,Q9HC07,P83436,O75787,P23786,O75648,Q10713 28 +Pelvic kidney 0.4186278418297867 0.4821704738520443 0.6296848498020191 1.0 1.0 9 Q9UHX1 1 +Right ventricular hypertrophy 0.6481421647819088 0.4815619731440772 0.630117145215795 1.0 1.0 3 Q15233,Q9H267 2 +Increased circulating prolactin concentration 0.4445163377547922 0.4794253952675576 0.6316360307074371 1.0 1.0 7 Q99496,Q9BUK6,P35222,O14802,Q969G3,Q12824 6 +Posterior pharyngeal cleft 0.6434108527131809 0.4792967919884273 0.6317275040350183 1.0 1.0 2 O15344 1 +Coarse hair 0.3574999672938649 0.4779499087765671 0.6326858577226102 1.0 1.0 19 Q9Y487,P54802 2 +Vertical supranuclear gaze palsy 0.3841942437087328 0.477564267938223 0.6329603681344782 1.0 1.0 13 O15118,P61916 2 +Peripheral axonal degeneration 0.3545883384197129 0.4772482434221459 0.6331853613100069 1.0 1.0 66 P00846,P07196,P07602,Q9BQT8,O95831,P03886,Q6DKK2,P41440,Q8IY17 9 +Infantile muscular hypotonia 0.3555667708688371 0.4762760021900827 0.6338777597088701 1.0 1.0 69 P00846,Q8N3U4,Q9UP83,P16278,O75306,P07602,Q13510,Q05086,O43819,Q9BVA1,P03886,O60762,Q9Y487 13 +Proportionate short stature 0.3264272321195968 0.4739418272115574 0.635541390989359 1.0 1.0 33 Q9Y619,Q96HY6,Q5JRA6,P52732,P16278,Q15392,P10619,Q8IY17 8 +Decreased number of large peripheral myelinated nerve fibers 0.4753275450571925 0.4730979614155899 0.6361432911296399 1.0 1.0 5 P07196 1 +Achilles tendon contracture 0.3997740172087872 0.4725344165149943 0.6365453819863252 1.0 1.0 11 Q08J23,P50402,Q8WXH0 3 +Atelectasis 0.406857175269462 0.4695390612450072 0.6386843712212724 1.0 1.0 10 P21964,Q92766,Q13510 3 +Abnormal pons morphology 0.3541802335600589 0.4685519662910775 0.6393899179528815 1.0 1.0 21 Q9UNW1,Q9BVA1,O60762,Q10713,Q9Y3B2 5 +Cerebellar vermis atrophy 0.4149400058806742 0.4651702730430228 0.6418095250422173 1.0 1.0 9 Q10713 1 +Abnormal cd4 cd8 ratio 0.4724706793912223 0.4625810701989328 0.6436646798648296 1.0 1.0 5 Q13432 1 +Degeneration of the lateral corticospinal tracts 0.4401673073976857 0.4613513542568568 0.6445465463678817 1.0 1.0 7 O75298 1 +Abnormal circulating bilirubin concentration 0.338027203466634 0.460034887147987 0.6454911793842433 1.0 1.0 28 Q9NSD9,Q9UGP8,P23786,P00390,P41440,Q9UJS0 6 +Specific learning disability 0.349756617114513 0.4591840100848696 0.6461020320888173 1.0 1.0 60 Q10713,P21964,Q9NSD9,Q9Y619,Q8N3U4,Q96RR1,Q92766,P00403,Q9BVA1,P03886,Q9H6K4,O43505,Q96DF8,Q13586 14 +Poor suck 0.3477126568576033 0.4567498719173655 0.6478508399809253 1.0 1.0 24 Q8N3U4,P22695,Q9H936,O75306,Q05086,O43464,O43819,O75648 8 +Progressive cerebellar ataxia 0.3327011452214529 0.4561416038674325 0.6482881546208037 1.0 1.0 40 Q9UBB4,Q9Y619,Q9BUK6,Q96CU9,O14773,Q9Y487,P41440,Q9P0J0,Q7KZN9 9 +Corpus callosum atrophy 0.3547069996533661 0.4553141466743103 0.6488832502132111 1.0 1.0 16 O75503,P51572 2 +Optic disc coloboma 0.5136707758668408 0.4552539917022629 0.6489265215719529 1.0 1.0 4 Q10713 1 +Abnormal circulating sulfur amino acid concentration 0.4208025195054485 0.4547412330989122 0.6492954130121236 1.0 1.0 8 Q6PGP7,P41440,Q9UJS0 3 +Increased susceptibility to fractures 0.3421356046952638 0.4538321540737139 0.6499496387434596 1.0 1.0 50 Q9Y2D4,P16435,Q14108,Q9UNW1,O95453,Q13126,O75718,Q32P28,O15269 9 +Multiple lipomas 0.4697704494018974 0.4527049430332019 0.6507612197229891 1.0 1.0 5 P53680,Q8TAA9,Q9BUK6,Q9Y2U8 4 +Micropenis 0.3481399849694789 0.4496364850584637 0.6529725758851184 1.0 1.0 59 Q10713,P16435,Q9Y619,Q9UP83,Q9UNW1,P48449,O95470,Q8IY17,Q9BZK7,Q9NVI7,P46977,O43505,Q03252,P42892,Q9BXW9 15 +Large basal ganglia 0.3537472839883641 0.4489332245999775 0.6534798276760789 1.0 1.0 17 Q71SY5,Q9UBB6,Q08J23,Q96N66 4 +Cholecystitis 0.419224332686868 0.4478464999667211 0.6542639816540186 1.0 1.0 8 O43681 1 +Abnormal nerve conduction velocity 0.3313974658186991 0.4448201579983741 0.6564497255807331 1.0 1.0 40 Q99720,O43681,Q9Y619,P50570,P07196,P07602,Q9NR77,O95831,Q71SY5,O15269 10 +Acanthosis nigricans 0.3939857181326636 0.4435178752058012 0.6573911928007794 1.0 1.0 11 O75431,P31751 2 +Weak voice 0.4442352146463823 0.4408536802116307 0.6593189287373344 1.0 1.0 6 O75787 1 +Functional abnormality of the gastrointestinal tract 0.3120414653284272 0.4400285122869408 0.6599164568633673 1.0 1.0 268 P00846,Q99720,Q14108,Q96F07,O75306,O14678,P07602,P00403,P35670,Q9BQP7,P15586,Q8IZA0,P03886,P50336,Q9Y584,Q9HA77,Q8NFF5,O15269,Q9UJS0,Q92766,Q9UGP8,Q13510,O15118,Q96A33,P21964,Q9NSD9,Q9Y619,P61916,O95453,Q6PGP7,Q9NZ08,P61978,Q96PU5,P08183,O00203,O43791,Q9UHX1,P42892,P16435,Q8N3U4,Q9UBB4,Q9BV10,Q9BUF5,Q96RR1,O95202,Q05086,P06280,Q8NC96,P83436,Q9NR77,O43819,P20700,Q9UEY8 53 +Encephalopathy 0.3474799850246415 0.4390459401631025 0.6606282489658057 1.0 1.0 103 Q96F07,Q6NUQ1,O75306,P07602,P00403,Q9NPL8,P03886,Q9NZJ7,Q16836,Q9HA77,Q7KZN9,Q9UJS0,O43676,Q9NVI7,O60762,O43772,Q9Y619,P35914,Q5KU26,O75380,O75746,P50416,Q86Y39,O96000,Q96RR1,Q96CU9,Q8NC96,P23786,Q9Y375,Q8TB37 30 +Perseveration 0.4346243889773956 0.4385457217864865 0.6609907337521113 1.0 1.0 7 Q9BSH4,P35637,P61916 3 +Abnormality of the biliary system 0.3344120815311074 0.4364196334170966 0.6625322966854488 1.0 1.0 119 Q9UJW0,O43681,Q14108,Q6NUQ1,P07602,P35670,Q71SY5,Q9UJS0,Q92766,Q13510,O15118,Q96A33,Q5XKP0,P21964,Q9NSD9,P61916,Q6PGP7,O75381,P09601,Q16625,P35914,O43791,O95202,P22830,P83436,O75787,O75648,Q10713,P14174 29 +Hypoplastic nipples 0.3997849604486119 0.4357279792571201 0.6630341031471014 1.0 1.0 10 Q96A33 1 +Pain in head and neck region 0.5074337427278619 0.4347217385071157 0.6637644173893946 1.0 1.0 4 Q99496,Q969G3,O75533 3 +Chromosomal breakage induced by ionizing radiation 0.5074337427278619 0.4347217385071157 0.6637644173893946 1.0 1.0 4 Q969G3,Q99496,Q92878 3 +Upper motor neuron dysfunction 0.3391046177849547 0.434292694873112 0.6640759079407923 1.0 1.0 366 P00846,Q99720,O43681,Q96F07,Q9BRK0,P07196,P07602,P00403,O00584,O95831,Q71SY5,P50336,P03886,O00400,Q9Y487,O43505,Q9HA77,Q5BJH7,Q7KZN9,O75027,P50897,Q15392,Q13510,Q92804,Q86XL3,Q9NVI7,P49366,O15118,Q9H6K4,Q9UBX3,Q9BVA1,O60762,Q5XKP0,Q13423,Q9Y619,P61916,P16278,O75381,Q9NZ08,Q16625,Q96N66,O75503,P35914,P51572,Q5KU26,O43791,P51648,O75746,Q9NR50,Q96B26,Q6DKK2,Q9NUQ7,P50416,Q10713,Q9UBB6,Q15165,Q8N3U4,Q9UBB4,Q9UNW1,O75298,Q8NC96,O75787,Q9NR77,O43819,Q08J23,O14773,P11117,P20700,Q9P0J0,Q9UEY8,Q8TB37,P49902,P41440,Q8IY17 74 +Progressive spastic quadriplegia 0.4159513636058622 0.433620894020077 0.6645637595740033 1.0 1.0 8 O43681 1 +Type 1 muscle fiber atrophy 0.433043991909094 0.4320926889596744 0.6656740481399768 1.0 1.0 7 P50402,P61978 2 +Glucose intolerance 0.3474011375750451 0.4317244189510207 0.665941717511773 1.0 1.0 102 P61457,P00846,P31751,P00403,Q9NPL8,Q8WWY3,P03886,O43676,Q03252,Q5JRA6,O95453,O75380,O75431,Q86Y39,O75844,O96000,Q96RR1,Q96CU9,Q9Y375,Q8TB37,Q06136,Q8IY17 22 +Short umbilical cord 0.6304956504431749 0.4308850176143343 0.6665519778723852 1.0 1.0 3 O75844 1 +Small placenta 0.6304956504431749 0.4308850176143343 0.6665519778723852 1.0 1.0 3 O75844 1 +Abnormality of the anterior fontanelle 0.3213661512046356 0.4307493617444574 0.6666506229399287 1.0 1.0 33 P16435,Q9Y619,O75381,Q08J23,O75718,Q9Y487,P20674 7 +Centrally nucleated skeletal muscle fibers 0.4151122132516067 0.4299899006922197 0.6672029877180552 1.0 1.0 8 Q13586 1 +Recurrent hypoglycemia 0.6297500933169619 0.4287949054882509 0.6680724866729668 1.0 1.0 3 P35914 1 +Abnormal exteroceptive sensation 0.3381480460453462 0.4259254975471414 0.6701621348432361 1.0 1.0 49 Q9NZ08,P07602,P06280,Q9NR77,O95831,P54802,Q8NCH0,Q9H6K4 8 +Shallow anterior chamber 0.6243540051679624 0.4225769126313648 0.6726039741391237 1.0 1.0 2 Q9Y2B2 1 +Tube feeding 0.3500474878925767 0.4202377744688624 0.6743117620952039 1.0 1.0 70 Q9UBB6,Q99720,Q8N3U4,Q9UP83,Q9BV10,P37268,Q9UHX1,P07602,Q96N66,P61978,Q71SY5,O75648,O60762,O43791,Q9NUQ7,Q08J23,Q9HA77 17 +Caudate atrophy 0.6233850129198868 0.4197843918343833 0.6746429680566859 1.0 1.0 2 Q96RL7 1 +Stenosis of the external auditory canal 0.4126733174250702 0.4194755406080129 0.674868626757112 1.0 1.0 8 O95202 1 +Rhizomelia 0.3806004048079386 0.418437326997866 0.6756274001678824 1.0 1.0 12 Q15392,Q9BV10,O75718 3 +Dystonia 0.2696102357890606 0.4165706454844903 0.6769924842165369 1.0 1.0 168 P00846,Q99720,O43681,P07602,O00584,Q71SY5,P03886,Q9HA77,Q5BJH7,Q7KZN9,Q86VD7,O14949,O15118,P16278,P51572,Q6DKK2,Q9UBB6,O43819,Q08J23,Q9P0J0 20 +Peripheral neuropathy 0.2786972798004923 0.416281966203243 0.6772036871684923 1.0 1.0 155 P00846,O43681,O75306,O95470,P07196,P07602,P00403,P35670,Q9NPL8,O95831,P50336,P03886,Q9NZJ7,Q03001,Q7KZN9,O15269,Q9Y2R0,Q9NVI7,O60762,P50570,Q5KU26,Q9P0J0,Q96RR1,Q96CU9,Q9NR77,P54802,O43819,Q10713,P41440,Q8IY17 30 +Increased total bilirubin 0.5012090313986175 0.4145653519418192 0.6784601167533384 1.0 1.0 4 P23786 1 +Recurrent fractures 0.3319387887583859 0.4130266577898913 0.6795870827941108 1.0 1.0 28 P16435,Q9UNW1,O95453,Q13126,O75718 5 +Abnormality of the musculature of the thigh 0.4111025649539497 0.4127349247766737 0.6798008339287847 1.0 1.0 8 P07196,P50402,Q8WXH0 3 +Urinary incontinence 0.3343682652285241 0.4085161739313426 0.6828947586953433 1.0 1.0 47 Q99720,O43681,Q9UP83,Q9UBB4,P50570,O75298,P07196,P07602 8 +Iris atrophy 0.6191860465116319 0.4077901594757173 0.6834277387759582 1.0 1.0 2 O60315 1 +Breathing dysregulation 0.6211613568084828 0.405030372151728 0.6854551857444868 1.0 1.0 3 Q10713 1 +Abnormality of the basal ganglia 0.3496966975686469 0.4044233628741532 0.6859014230078149 1.0 1.0 89 P00846,Q9UBB6,P16278,Q9NR45,P00403,P23786,O43819,O95831,Q08J23,P03886,Q9P0J0,Q7KZN9 12 +Abnormal elasticity of skin 0.3441580385771863 0.402225661658524 0.6875179581535784 1.0 1.0 61 P07437,O96000,O75844,P38435,O95453,Q13126,Q9BZK7,Q8NCH0,Q9Y487,Q9UHX1,Q9NWM8 11 +Resting tremor 0.3427424935022454 0.3917956654907185 0.6952091979866486 1.0 1.0 21 Q9H6K4,O75787,P07602,Q96RR1 4 +Abnormality of fundus pigmentation 0.6157131204266078 0.3902622807551572 0.6963426119368015 1.0 1.0 3 P38435 1 +Hypopigmentation of the fundus 0.6157131204266078 0.3902622807551572 0.6963426119368015 1.0 1.0 3 P38435 1 +Abducens palsy 0.4932113343035266 0.3891844975654492 0.6971396704196251 1.0 1.0 4 P07602 1 +Type ii diabetes mellitus 0.3187409470875053 0.3869914052631683 0.6987625707991132 1.0 1.0 35 P03886,P31751,Q8IY17 3 +Abnormality of the glabella 0.4049312061944682 0.3864967555224218 0.6991288050155977 1.0 1.0 8 O95202,O43791 2 +Adenocarcinoma of the small intestine 0.6114341085271187 0.3861120437669373 0.6994136905495523 1.0 1.0 2 P78549 1 +Duodenal adenocarcinoma 0.6114341085271187 0.3861120437669373 0.6994136905495523 1.0 1.0 2 P78549 1 +Abnormality of muscle size 0.2784773703899872 0.3844795793537162 0.7006230283102601 1.0 1.0 191 Q99720,P07196,Q9NPL8,Q9BQP7,O95831,Q71SY5,O00400,Q9Y487,O43505,Q13586,Q9NWM8,O15269,Q7LGA3,Q13510,Q9BQT8,O43175,Q92804,Q9NVI7,Q9BVA1,Q9NQT5,Q8WXH0,Q96A33,Q03252,O95817,O14979,Q99575,P16278,P50570,Q9NRZ9,P50402,P61978,Q96B26,Q6DKK2,P50416,Q15165,Q9BUK6,Q9UNW1,O75298,Q6P4A7,Q05086,P83436,Q13126,Q9NR77,O43819,O75648,Q10713,Q8IY17 47 +Hypopigmented skin patches 0.3355503967092964 0.3842879979891339 0.7007650025734831 1.0 1.0 25 P21964,O95453,Q92766,P07602,Q8IZA0,Q9BXW9 6 +Elevated gamma glutamyltransferase level 0.4503872837156094 0.3837822764181166 0.7011398253835823 1.0 1.0 5 Q5XKP0 1 +Generalized hypopigmentation of hair 0.3955938664982557 0.378144671029374 0.7053231250541838 1.0 1.0 9 O95453,O00203 2 +Petechiae 0.3717316639293372 0.3730454212891252 0.7091146386937912 1.0 1.0 12 Q16625 1 +Meningocele 0.3943336849954362 0.3726147556995193 0.7094351890552375 1.0 1.0 9 Q10713,P21964 2 +Confusion 0.3410193786860508 0.371679397954627 0.7101315659042422 1.0 1.0 16 Q9Y619,O96008,Q9NZ08,Q8NBM4,Q16836,Q9UJS0 6 +Oromotor apraxia 0.4464181745686347 0.3701284316554825 0.7112867986780069 1.0 1.0 5 Q9BVA1 1 +Inflammation of the large intestine 0.378707180176572 0.3686900931333576 0.7123587338797752 1.0 1.0 11 Q6PGP7,P49748,P08183 3 +Coxa valga 0.340026876576753 0.3652679808332398 0.7149113771793612 1.0 1.0 19 O75844,P16278,Q96A33 3 +Abnormality of the achilles tendon 0.3630155003355884 0.3629713428442644 0.7166262916401336 1.0 1.0 13 Q08J23,P50402,Q8WXH0 3 +Heteronymous hemianopia 0.4442289039767191 0.3626688294896006 0.7168522870888681 1.0 1.0 5 P35222,Q99496,Q969G3,Q12824 4 +Dysplastic corpus callosum 0.3772436416630393 0.3616707511867386 0.7175980866399314 1.0 1.0 11 P49902,P20700 2 +Retinal degeneration 0.3342304795046003 0.3616645444003763 0.7176027254142303 1.0 1.0 53 P50897,Q96F07,Q13510,O75503,Q8NC96,Q8WWY3,P51648,Q10713,O14773,Q8IY17 10 +Bone marrow foam cells 0.6035426441161276 0.3581722514174603 0.7202144117388116 1.0 1.0 3 O15118 1 +Abnormal metatarsal morphology 0.3375184603420665 0.3574222278993115 0.7207757388144356 1.0 1.0 21 P16435,O95202,Q15392,Q08J23,O43505 5 +Rod cone dystrophy 0.3211933685227978 0.3572722137513947 0.720888029367682 1.0 1.0 40 P00846,P38435,O75381,Q8WWY3,P03886,P04114 6 +Depression 0.3436257623811347 0.3565474021429485 0.7214306595876503 1.0 1.0 95 O43681,P07602,P00403,P35670,Q71SY5,P03886,Q9NZJ7,P50897,Q92766,Q92804,P21964,Q96N66,Q6DKK2,Q9NUQ7,Q9UBB6,Q15165,Q8N3U4,Q9UBB4,Q9BUK6,Q96RR1,P06280,Q08J23,P20700 23 +Thin skin 0.3373835932195574 0.3565411120634256 0.7214353692699671 1.0 1.0 21 O75844,Q9Y619,O75431,Q13126 4 +Renal tubular atrophy 0.4825468648998078 0.3562980409794531 0.7216173762640092 1.0 1.0 4 Q8WUM0,P57740,Q96AX1 3 +Abnormality of central nervous system electrophysiology 0.2982688255528347 0.3551946713603555 0.7224437564445645 1.0 1.0 142 Q14108,Q96F07,P48449,P07196,P07602,P00403,Q71SY5,P03886,Q9HA77,P50897,Q8NHS3,P49366,O60762,Q9UBX3,Q96A33,P13073,P21964,O75381,Q96N66,O75503,P35914,Q9NUQ7,Q9UBB6,Q9UBB4,O95202,Q8NC96,Q08J23,P20700 28 +Abnormality of the septum pellucidum 0.3205079776995217 0.351466933445638 0.7252380753820691 1.0 1.0 40 Q9UBB6,Q8N3U4,Q9BV10,O95202,P51571,Q15392,Q96N66,Q71SY5,Q9BVA1,Q08J23,O43505,Q9NUQ7 12 +Impairment of activities of daily living 0.3373114499854645 0.3507909120640204 0.7257452156234794 1.0 1.0 59 P21964,Q99720,O43681,Q9UP83,P50570,O75298,Q92766,P07196,P07602,P20700,O15269 11 +Abnormal bleeding 0.3410912985378526 0.3502671450625688 0.7261382198117978 1.0 1.0 100 O75844,P21964,Q14108,P38435,Q9NZ08,Q16625,Q9UGP8,Q13126,P23786,Q9BZK7,Q13586,Q8NCH0,P11117,Q96PU5,Q9Y487,Q9UHX1,Q9NWM8,Q9UJS0 18 +Muscle spasm 0.3372382538433875 0.3501303197218743 0.7262408974441898 1.0 1.0 59 P00846,Q15165,O75298,P07196,P06280,P23786,Q9NR77,Q9H6K4,P53985 9 +Truncal ataxia 0.3376282877073323 0.3489336977962713 0.7271390860602904 1.0 1.0 18 O75503,Q9BUK6 2 +Chorioretinal dysplasia 0.5995170469975881 0.3478410442319172 0.7279595633265246 1.0 1.0 3 O43505 1 +Kyphoscoliosis 0.3292553418947757 0.3477785992397289 0.7280064629128651 1.0 1.0 49 O75844,Q9HC07,Q9NR77,Q5KU26,Q8NCH0,Q9Y487 6 +Pseudobulbar paralysis 0.4112242004517528 0.3454818905760427 0.7297321223725559 1.0 1.0 7 Q15233,P54136,P20700 3 +Dysmetria 0.3330369171669233 0.3441718224128657 0.730717071755195 1.0 1.0 54 Q9BUK6,Q6P4A7,O75503,Q9NPL8,O75787,Q96TA2,P20700,Q10713,Q6DKK2,O14773,P41440 11 +Abnormality of retinal pigmentation 0.3418601878457747 0.3392420576997893 0.7344273883107093 1.0 1.0 71 P00846,P52732,Q9BUK6,O75306,Q8NHS3,O75381,Q96CU9,P00403,Q13432,Q8WWY3,P03886,P51648,Q9P0J0,Q7KZN9,Q8IY17 15 +Renal tubular dysfunction 0.3176073946181171 0.3367199281244473 0.7363280392954401 1.0 1.0 39 O43676,O96000,O75306,Q96CU9,P00403,Q9NPL8,O43819,Q8TB37,P03886,Q9Y375,O75380,P50416,Q86Y39 13 +Neuronal loss in basal ganglia 0.5937466202545443 0.3332856884919264 0.7389186413771385 1.0 1.0 3 O43819 1 +Limitation of movement at ankles 0.4744381223355368 0.33206892007828 0.7398372179607389 1.0 1.0 4 O75844 1 +Epileptic encephalopathy 0.3293867565755094 0.3284021984446391 0.7426075809674217 1.0 1.0 24 Q9HA77,Q96F07,O75746,Q8NC96 4 +Pulmonary fibrosis 0.3329207018445341 0.3275733871755109 0.743234246585597 1.0 1.0 21 O95453,P09601,O00203,Q8IZA0,P14174 5 +Abnormal metabolism 0.3284937036636602 0.3258131768182658 0.7445657086098723 1.0 1.0 51 Q9NSD9,Q9UP83,P46783,Q9BT22,O75787,P46977,Q9Y487,P41440,Q8N511 9 +Micrographia 0.59016972330616 0.3244162843515518 0.7456228927305852 1.0 1.0 3 Q96RL7 1 +Hypophosphatemia 0.4715578539107966 0.3236312779516666 0.7462172049418494 1.0 1.0 4 P53680,Q6P1J9,P51798 3 +Bruxism 0.3893828615257829 0.3222804771935997 0.7472402217330858 1.0 1.0 8 Q12955,Q96RL7,P61978 3 +Abnormality of circulating glucocorticoid level 0.3613267535836041 0.3211445370411522 0.7481008606548774 1.0 1.0 12 Q13423 1 +Fibrous tissue neoplasm 0.3329281358084283 0.3209051929445814 0.7482822385030587 1.0 1.0 19 Q13126 1 +Abnormality of peripheral nerves 0.3200352717914496 0.3194856424106097 0.7493582770822735 1.0 1.0 43 Q99720,O43681,Q9Y619,P50570,P07196,P07602,Q9NR77,O95831,Q71SY5,O15269 10 +Weak cry 0.3818635181791713 0.3189324146032968 0.7497777635632121 1.0 1.0 9 O75208,Q13510 2 +Vocal cord paresis 0.469618616677442 0.3180014277835952 0.750483853871682 1.0 1.0 4 Q8TB36,P36776,P43243 3 +Vertebral fusion 0.3740391379462877 0.3173281252842581 0.7509946384246615 1.0 1.0 10 Q9UHX1 1 +Abnormal sternal ossification 0.4301367137370628 0.3159334837547614 0.7520529962181857 1.0 1.0 5 O95202 1 +Aplasia hypoplasia involving the pelvis 0.3319113344270357 0.315108925977735 0.7526789515547792 1.0 1.0 17 Q9Y2D4,Q96HY6,O95202,Q9NR45,O95831,O75431 6 +Distal amyotrophy 0.3294207448326487 0.3123376835708777 0.7547839041459121 1.0 1.0 54 Q99720,Q9BUK6,P07196,Q13510,Q9BQT8,Q9NR77,Q9NVI7,Q71SY5,O15269,Q8IY17 10 +Abnormal synaptic transmission at the neuromuscular junction 0.3269258933608631 0.3116393221009651 0.7553146466886078 1.0 1.0 24 Q15165,Q13586,Q9UNW1 3 +Epileptic spasm 0.3341953492193802 0.3114958601921192 0.7554236895491622 1.0 1.0 61 P00846,Q9UBB6,Q13510,Q08J23,P03886,Q9UBX3,P13073 7 +Infantile onset 0.2642155325096331 0.309961170341037 0.75659048465304 1.0 1.0 169 Q6NUQ1,O75306,Q9NRW7,P07602,Q9NPL8,O00584,O95831,Q70HW3,O00400,Q5BJH7,P06865,Q9NVI7,P49366,O60762,Q53H12,Q5XKP0,Q9NSD9,Q5JRA6,O95453,O75746,P20674,Q9P0J0,O75431,Q9UBB6,Q9Y375,Q9BUF5,Q96CU9,O75787,P23786,Q9NR77,O75648,Q96TA2,P20700,Q10713,Q9UEY8 35 +Peripheral axonal neuropathy 0.3283329095378497 0.3098272296724835 0.756692343537428 1.0 1.0 53 P00846,P07196,P07602,O95831,P03886,Q8IY17 6 +Abnormal peripheral nervous system physiology 0.3228890179250731 0.3090601952670177 0.757275737423261 1.0 1.0 47 Q99720,O43681,Q9Y619,P50570,P07196,P07602,Q9NR77,O95831,Q71SY5,P20700,O15269 11 +Abnormality of chromosome stability 0.3375109878970514 0.3037163173363023 0.761344025459487 1.0 1.0 15 P13073,P33991,Q9BXW9 3 +Fatigable weakness of skeletal muscles 0.3844489112287333 0.3025230313170566 0.7622533790129473 1.0 1.0 8 Q9UNW1 1 +Platyspondyly 0.3071246303906664 0.30111827781652 0.7633243037996136 1.0 1.0 34 Q5JRA6,Q96HY6,P16278,Q6NUQ1,Q9NR45,O95831,Q32P28,Q9NUQ7 8 +Abnormal vitamin b12 level 0.4063096314767724 0.3001001813879473 0.7641007408491309 1.0 1.0 6 P41440 1 +Cavum septum pellucidum 0.3440270384170881 0.2992473573480574 0.7647513178599927 1.0 1.0 14 O95202,Q71SY5,Q9BVA1 3 +Serositis 0.329216439839148 0.2978311896629073 0.7658320082990562 1.0 1.0 18 P14174,P57740,Q8N1F7,Q9NZ08 4 +Abnormality of tibia morphology 0.3636047741508794 0.2976746566458975 0.7659514880852458 1.0 1.0 11 P16435,O95831,Q32P28 3 +Abnormal lower limb bone morphology 0.2606255284183877 0.2969999547521976 0.7664665436809921 1.0 1.0 163 Q9Y2D4,Q96HY6,Q6NUQ1,P07602,O95831,Q71SY5,Q9BZK7,Q9NZJ7,Q9Y487,O43505,Q7LGA3,Q92766,Q15392,Q13510,Q96A33,Q32P28,Q03252,P13073,Q9BXW9,P21964,Q9Y619,Q5JRA6,P16278,Q9NR45,Q9UHX1,O75431,Q9NUQ7,O75844,P16435,Q9BV10,O95202,P06280,O75787,Q08J23,O75648,O75718,Q10713 37 +Muscle hypertrophy of the lower extremities 0.4050372840486909 0.2956624499442699 0.7674878763197204 1.0 1.0 6 Q9NR77 1 +Rhabdomyolysis 0.3355841214727302 0.2930733416989511 0.7694660928030916 1.0 1.0 15 O43772,P23786 2 +Patellar aplasia 0.4224721004857794 0.2915008610509185 0.7706682854332789 1.0 1.0 5 Q56NI9,Q9Y619,Q9Y5S9 3 +Abnormality of urine homeostasis 0.2700191579243971 0.2887086538750938 0.7728043397505648 1.0 1.0 184 P61457,P00846,Q14108,O95470,P00403,Q9BZK7,P50336,P03886,O75880,Q8NFF5,Q9UJS0,Q9BQT8,Q9NVI7,Q9H6K4,P53985,Q53H12,Q5XKP0,Q03252,Q13423,O43772,Q8N1F7,Q9Y619,Q5JRA6,P16278,Q4J6C6,P09601,P35914,O75431,O96000,P06280,P23786,P54802 32 +Short stepped shuffling gait 0.572351421188637 0.2867044894977876 0.774338599723724 1.0 1.0 2 P04062 1 +Ankle clonus 0.3413672005838249 0.2852330790031727 0.7754655791196174 1.0 1.0 14 O75298,Q8N0X7,P07602,O75787,Q9NZJ7 5 +Skeletal dysplasia 0.3113179104321019 0.2843804755701224 0.7761188198408011 1.0 1.0 39 Q96HY6,P16278,Q9NR45,O75381,Q9HC07,P10619,O95831,P51648,Q9NUQ7 9 +Short clavicles 0.366432991467821 0.2840054930849411 0.7764061710331744 1.0 1.0 10 O75844 1 +Small pituitary gland 0.5707364341085264 0.2829731714145487 0.7771974029342523 1.0 1.0 2 Q14746 1 +Decreased adipose tissue 0.3408871261078116 0.2827174746713041 0.7773934196719605 1.0 1.0 14 O75844,O75431 2 +Heat intolerance 0.4546312457834133 0.2759290657170595 0.7826025489915109 1.0 1.0 4 P61978 1 +Broad phalanx of the toes 0.3985252389716095 0.2732763345219656 0.7846408055284988 1.0 1.0 6 Q7LGA3,Q71SY5 2 +Abnormality of earlobe 0.3176870400243686 0.2726389489057171 0.7851307688479527 1.0 1.0 26 P21964,P16435,Q92766,Q15392,Q9BZK7 5 +Extramedullary hematopoiesis 0.4532436534278991 0.2721667834892363 0.7854937810183014 1.0 1.0 4 Q9NRW7 1 +Atypical absence seizure 0.4523635211424816 0.2697924296145952 0.7873199472313808 1.0 1.0 4 Q05086 1 +Bulbous nose 0.3151610720188191 0.2696200010969318 0.7874526113732285 1.0 1.0 44 P21964,P16435,Q92766,P42892,P23786,O43791,Q96A33,Q96DF8,O75431 9 +Abnormal magnesium concentration 0.4152340789160936 0.2691084918417792 0.7878461958667946 1.0 1.0 5 P61457 1 +Skin vesicle 0.3499854067790633 0.2664714305544637 0.7898761593313277 1.0 1.0 12 P98194,O95453,P16615 3 +Generalized hypopigmentation 0.3899209130289197 0.2661063327035891 0.7901573179980392 1.0 1.0 7 O00203 1 +Abnormality of the ribs 0.328359878705146 0.2650438226852692 0.79097570298693 1.0 1.0 60 O75844,Q9Y2D4,P16435,Q9Y619,Q96HY6,Q9BV10,P50570,P16278,O95202,O95831,P54802,O75718,Q32P28,Q9UHX1,O75431 15 +Underdeveloped nasal alae 0.3220426989254085 0.2633755086987324 0.7922611656380223 1.0 1.0 22 Q08J23,Q96DF8,Q5KU26,O75431 4 +Abnormal myelination 0.2806437279793305 0.2595960482309754 0.7951753849101273 1.0 1.0 212 P00846,Q99720,O43681,Q96F07,Q9H936,O75306,P07196,P07602,P00403,P35670,P08243,O00584,O95831,Q9NPL8,O00400,P03886,Q9NZJ7,Q9Y584,Q5BJH7,Q7KZN9,O15269,O43676,Q9Y6M9,Q9UP83,Q7LGA3,P54136,O43175,Q8TD30,Q8IUX1,O60762,O95817,P50570,P51572,Q6ZXV5,Q5KU26,O75380,P51648,O75746,Q9NR50,Q13868,Q86Y39,Q9Y3B2,O96000,Q9UBB6,Q8WXI9,Q9Y375,Q9BV10,Q96CU9,P10253,Q05086,Q8NC96,O75787,Q9NR77,O43819,P83436,Q9H553,P20700,Q9P0J0,Q8TB37,P41440,P00374 61 +Abnormal blood monovalent inorganic cation concentration 0.3214869729962665 0.2578766757135742 0.7965020862803174 1.0 1.0 16 P50336,Q13423 2 +Abnormal pelvis bone morphology 0.5613850497710018 0.2575184908725199 0.7967785428644154 1.0 1.0 3 P16435 1 +Primary adrenal insufficiency 0.3289855236150704 0.257176667311089 0.7970423951589747 1.0 1.0 15 O75381,Q13423 2 +Gonadal dysgenesis 0.3600814842126038 0.2568482647139746 0.7972959097108547 1.0 1.0 10 Q9UNW1,Q96RR1 2 +Platybasia 0.4106768027807334 0.2553625121478991 0.7984431221097945 1.0 1.0 5 P21964 1 +Eeg with multifocal slow activity 0.3723102508495886 0.2553287525442792 0.7984691943949804 1.0 1.0 8 Q8NC96 1 +Eeg with abnormally slow frequencies 0.3207866871096348 0.2502889593169374 0.8023638939986961 1.0 1.0 17 P20700,Q96F07,O75503,Q8NC96 4 +Micromelia 0.3199448589278232 0.2500891303770314 0.8025184216521093 1.0 1.0 22 Q9UHX1,Q15392,O75718 3 +Secondary growth hormone deficiency 0.4440853264382694 0.247923972060855 0.8041932318043334 1.0 1.0 4 Q99496,Q969G3,Q12824 3 +Weakness of facial musculature 0.3246655394107634 0.2446180188534765 0.8067522108366312 1.0 1.0 58 O95817,Q86VD7,P50570,Q9BUK6,Q9BUF5,Q96RR1,O75381,P07196,Q13510,Q9BQT8,Q9BQP7,O43819,O60313,Q96TA2,Q9UHX1 15 +Intrauterine growth retardation 0.2736387770774289 0.2414488263090062 0.8092072739498479 1.0 1.0 198 O75306,Q9NPL8,P57740,P03886,Q9Y584,Q9Y487,O75880,Q16836,Q5BJH7,O75027,Q9UJS0,O43676,Q9UP83,Q9BT22,P37268,Q92766,Q15392,O75208,P33991,Q9BXW9,P21964,Q9NSD9,Q9Y619,P16278,O95453,Q6PGP7,P51572,O75380,Q9UHX1,Q86Y39,O75844,O96000,Q9BV10,Q6P4A7,O95202,Q96CU9,P83436,Q08J23,Q9Y375,Q8TB37 40 +Polymicrogyria 0.3313705647354696 0.2413061673992446 0.8093178312160811 1.0 1.0 71 P07437,Q9UBB6,Q10713,O43505,P37268,O75381,Q15392,Q16625,Q96N66,P23786,Q71SY5,Q9BVA1,Q08J23,Q9Y487 14 +Broad foot 0.3559277953012108 0.2394382840569234 0.8107657468004967 1.0 1.0 10 O95831 1 +Chronic oral candidiasis 0.5525591134127504 0.2386771597745166 0.8113559288138394 1.0 1.0 3 O00203 1 +Genu varum 0.3501682819149594 0.2374283506945098 0.8123244977601605 1.0 1.0 11 Q9Y619,Q96HY6 2 +Attenuation of retinal blood vessels 0.3813800416925292 0.2359586876852761 0.8134647275139115 1.0 1.0 7 P04439,P38435 2 +Mildly elevated creatine kinase 0.3181787462045017 0.2319826548691447 0.8165514857618805 1.0 1.0 19 Q9BUK6,P50570,Q96RR1,O75648,Q9H553,Q969X5,Q16836 7 +Multiple prenatal fractures 0.3798884403779715 0.230800488475487 0.8174698017302808 1.0 1.0 7 O75718 1 +Laryngeal cleft 0.5461886304909642 0.230160082572805 0.8179673786954182 1.0 1.0 2 Q69YQ0 1 +Suicidal ideation 0.5461886304909641 0.2301600825728042 0.8179673786954189 1.0 1.0 2 Q14203 1 +Cutis laxa 0.3019476973073234 0.2299791559421359 0.8181079667794409 1.0 1.0 30 Q9Y487,O96000,Q8NCH0 3 +Gray matter heterotopia 0.3114765438833545 0.2299741256872386 0.8181118755960783 1.0 1.0 26 Q86XL3,Q96PU5,Q9BVA1,O43505,Q9UEY8 5 +Abnormal heart sound 0.3796374811875958 0.2299358348500123 0.8181416300737749 1.0 1.0 7 P04114 1 +Hyperkinetic movements 0.3481726816723966 0.228743670844657 0.81906815009654 1.0 1.0 11 P07602 1 +Paraplegia paraparesis 0.3322116382325938 0.2249952217526191 0.8219829914618373 1.0 1.0 82 P00846,O75298,Q13510,O95831,Q9H6K4,Q9P0J0,Q6DKK2,Q5XKP0,P49902,Q7KZN9,Q8IY17 11 +Limb girdle muscular dystrophy 0.3639045865492624 0.2239194768503181 0.8228199601696853 1.0 1.0 8 P50402,Q8WXH0 2 +Areflexia 0.3316571372359024 0.2206800052915699 0.8253416011231591 1.0 1.0 81 P07196,O95831,Q71SY5,O43505,Q13586,Q9HA77,O15269,Q9BT22,Q13510,Q9BQT8,Q9H6K4,P50570,P61978,O14653,O75787,Q9NR77,O43819,P41440,Q8IY17 19 +Frontotemporal dementia 0.3768830369327564 0.2205069998719246 0.8254763214290306 1.0 1.0 7 P22626,P35637,O96008 3 +Abnormal venous morphology 0.3094570365021433 0.2163207028062719 0.8287377725801945 1.0 1.0 26 Q9Y487,Q92766,Q71SY5,P21964 4 +Abnormal platelet function 0.4312489683568709 0.2157253090211404 0.8292018719433905 1.0 1.0 4 O00203 1 +Focal white matter lesions 0.3753162548015455 0.2151943893732462 0.8296157650940856 1.0 1.0 7 O00584 1 +Episodic ataxia 0.4305106658047853 0.2139384585899486 0.8305950488529714 1.0 1.0 4 O14936,P11166,Q9H936 3 +Abnormal muscle glycogen content 0.3959717492966604 0.2129632333457742 0.8313556403694382 1.0 1.0 5 Q9BUK6 1 +Progressive pes cavus 0.3800116684970762 0.2128170053379487 0.8314696992311572 1.0 1.0 6 O75298 1 +Restless legs 0.3950930879855158 0.2105276430561818 0.8332558790352083 1.0 1.0 5 P07196 1 +Gastrointestinal obstruction 0.3376682497094754 0.2096598387322615 0.8339331728563195 1.0 1.0 12 P42892 1 +Lipid accumulation in hepatocytes 0.3297783936814404 0.2095773702578911 0.833997543311598 1.0 1.0 77 Q6NUQ1,P31751,P35670,P04114,O75880,Q9HA77,Q7KZN9,Q9UJS0,Q8N511,O60762,Q03252,Q5XKP0,O43772,Q9NSD9,P35914,P50416,O75431,O75787,P23786,O75648,Q9Y375 21 +Productive cough 0.3544651729900912 0.208652140656387 0.8347198039345138 1.0 1.0 9 Q9NVR5,Q9BZK7 2 +Facial hypotonia 0.3433754454162697 0.2081644825251158 0.8351005399397757 1.0 1.0 11 Q8N3U4,Q7Z3K3,Q13555,Q14738,P10253,Q96JM3,O00754,P30153,Q15907,Q00577 10 +Hypoplasia of teeth 0.3132690933339792 0.2080509973373665 0.8351891483303728 1.0 1.0 17 O75844,P51648 2 +Radioulnar dislocation 0.5372769847612229 0.2079982179883358 0.8352303587664001 1.0 1.0 3 P16435 1 +Abnormality of the radioulnar joints 0.5372769847612229 0.2079982179883358 0.8352303587664001 1.0 1.0 3 P16435 1 +Abnormal labia minora morphology 0.3592076872336498 0.2068546740940021 0.836123355683549 1.0 1.0 8 Q9Y619 1 +Broad palm 0.3539330139501787 0.2066285851824153 0.8362999342531043 1.0 1.0 9 O95831 1 +Appendicular hypotonia 0.5319767441860553 0.2030081494686692 0.8391286624884005 1.0 1.0 2 P04062 1 +Abnormal circulating long chain fatty acid concentration 0.3922356528322612 0.202685606051556 0.8393807743714086 1.0 1.0 5 P23786 1 +Distal arthrogryposis 0.391464554858231 0.2005901144760034 0.8410190884735638 1.0 1.0 5 Q8NCH0 1 +Abnormality of metacarpal epiphyses 0.391446723494274 0.2005417617942817 0.841056900113295 1.0 1.0 5 O95202 1 +Periodontitis 0.3462400252406824 0.1999798220992606 0.8414963619949631 1.0 1.0 10 O95453,O00203 2 +Congenital bilateral hip dislocation 0.5293927648578898 0.1983451598082752 0.8427750210616893 1.0 1.0 2 Q9Y4R8 1 +Spina bifida 0.2945537161019568 0.1970067218568485 0.8438222775882753 1.0 1.0 31 P21964,Q92766,Q08J23,Q10713,Q9UHX1 5 +Soft tissue sarcoma 0.2973411272420103 0.1958887000680811 0.8446972819649818 1.0 1.0 30 Q13126,Q15392 2 +Dysuria 0.3745148771021943 0.1958367938619631 0.844737910306939 1.0 1.0 6 P00492,Q8N0X7,P07741,O76024,O00170 5 +Eeg with focal epileptiform discharges 0.2964923425300646 0.1951154598098695 0.8453025599941135 1.0 1.0 36 Q9UBB6,Q96N66,O75503,Q71SY5,Q08J23,Q9UBX3,Q9NUQ7,Q9HA77 8 +Malabsorption 0.3100992829441865 0.1938329628342123 0.846306675852968 1.0 1.0 48 O95453,O75381,Q9NZ08,P09601,P06280,Q08J23,Q96A33,P14174 8 +Abnormal aortic valve cusp morphology 0.3074747853300079 0.1924800859963578 0.8473661653320408 1.0 1.0 25 P37268,Q9UHX1,Q6PGP7,O15294 4 +Abnormal thalamic size 0.5258397932816572 0.192071428398281 0.8476862550400888 1.0 1.0 2 Q9UPT5 1 +Abnormality of the calf 0.3185561518430184 0.1920105794933275 0.8477339183823813 1.0 1.0 58 P16435,Q9Y619,Q9UP83,Q96HY6,P16278,Q9NR45,Q13126,Q9NR77,O95831,O75718,Q32P28,Q9NUQ7,O75431 13 +Abnormal anatomic location of the heart 0.3336834793989218 0.1919120614182688 0.8478110894108095 1.0 1.0 12 Q10713,O75844 2 +Heinz bodies 0.5255167958656377 0.1915090067424974 0.8481268247729155 1.0 1.0 2 O14936 1 +Abnormal endocardium morphology 0.3225552531155914 0.1901224690493299 0.8492131634375633 1.0 1.0 14 P06280 1 +Asthma 0.3149990962149959 0.1841981074100174 0.8538580441469918 1.0 1.0 15 Q08J23,P21964,Q92766 3 +Pituitary hypothyroidism 0.3690168175937846 0.1793241658113021 0.8576831728240863 1.0 1.0 6 Q99496,P35222,Q969G3,Q12824,O00170 5 +Microcornea 0.2976624665169023 0.1792182479214495 0.8577663359236014 1.0 1.0 29 P07437,Q9BZK7,Q71SY5,Q8NCH0,O43505,Q9NWM8 6 +Telecanthus 0.3001905821227896 0.1754634976798939 0.8607154504220105 1.0 1.0 41 O75844,P21964,Q86XL3,Q9BZK7,Q08J23,Q8NCH0 6 +Short palpebral fissure 0.2992938589926853 0.174343021402545 0.8615958907394632 1.0 1.0 28 P07437,O75844,Q9Y619,Q9UHX1,Q9BXW9 5 +Hypogonadotropic hypogonadism 0.3057235529891092 0.1731574611857612 0.8625276595401865 1.0 1.0 24 P03886,Q8IY17 2 +Gastrointestinal inflammation 0.3071770206431188 0.1712582960393017 0.8640206708859122 1.0 1.0 18 Q04656,P49748,Q9Y2V7,Q6PGP7,O43175,P08183 6 +Lens subluxation 0.5125968992248103 0.170092693234915 0.864937239739386 1.0 1.0 2 Q99496 1 +Mydriasis 0.5125968992248103 0.170092693234915 0.864937239739386 1.0 1.0 2 Q99496 1 +Abnormal ciliary body morphology 0.5125968992248103 0.170092693234915 0.864937239739386 1.0 1.0 2 Q99496 1 +Ocular pain 0.5125968992248103 0.170092693234915 0.864937239739386 1.0 1.0 2 Q99496 1 +Inferior lens subluxation 0.5125968992248103 0.170092693234915 0.864937239739386 1.0 1.0 2 Q99496 1 +Choroidal melanoma 0.5125968992248103 0.170092693234915 0.864937239739386 1.0 1.0 2 Q99496 1 +Metamorphopsia 0.5125968992248103 0.170092693234915 0.864937239739386 1.0 1.0 2 Q99496 1 +Photopsia 0.5125968992248103 0.170092693234915 0.864937239739386 1.0 1.0 2 Q99496 1 +Uveal melanoma 0.5125968992248103 0.170092693234915 0.864937239739386 1.0 1.0 2 Q99496 1 +Contractures of the joints of the lower limbs 0.3159570607442472 0.1699818606661844 0.8650244021338556 1.0 1.0 58 Q99720,P37268,Q86XL3,Q08J23,Q8IZA0,P49902 6 +Ophthalmoparesis 0.3235172894912809 0.1699239203251491 0.8650699689863433 1.0 1.0 71 P00846,P50570,Q96RR1,Q96IX5,Q96CU9,P00403,Q9BQP7,Q8WWY3,O43819,P03886,Q10713,Q13586,Q9P0J0,Q7KZN9 14 +Arrhinencephaly 0.3385131206895315 0.1697359827812777 0.865217774488356 1.0 1.0 10 P21964 1 +Emg myopathic abnormalities 0.2986155242386217 0.1696897618647004 0.8652541261477413 1.0 1.0 28 P50570,Q9BUK6,Q96RR1,P07196,P50402,Q8WXH0,Q13586 7 +Bone marrow hypercellularity 0.3380829015544022 0.1680857260321825 0.8665158385615399 1.0 1.0 10 P40763,P27797,Q6UN15,Q6W2J9,Q9BZK7,P10644,P49327,P62263,P06748 9 +Limited hip movement 0.304649487786911 0.1664727730174472 0.8677849081670801 1.0 1.0 16 O75844,Q7LGA3,Q03001 3 +Hypokalemia 0.3644890038809772 0.166089639559115 0.8680864073497503 1.0 1.0 6 Q9H3U1,P05023,Q08426,Q9UNF1,O00170 5 +Widow s peak 0.4085326438267633 0.1641179002576236 0.869638330509009 1.0 1.0 4 P29372,O15344,Q69YQ0 3 +Vitreous hemorrhage 0.5127625201938457 0.1640858153588155 0.8696635881674613 1.0 1.0 3 P35222,Q99496 2 +Reduced natural killer cell count 0.4081346278347955 0.1632770474802689 0.8703003048366622 1.0 1.0 4 P33991 1 +Abnormal natural killer cell morphology 0.4081346278347955 0.1632770474802689 0.8703003048366622 1.0 1.0 4 P33991 1 +Vertical nystagmus 0.5080749354005263 0.1630933271065073 0.8704449536513692 1.0 1.0 2 Q9NW15 1 +Poor motor coordination 0.3168984885024226 0.1630495136148436 0.8704794500282995 1.0 1.0 14 O75503 1 +Episodic pain 0.3265759130190149 0.1610837485016873 0.8720274399029497 1.0 1.0 12 Q13423 1 +Aplasia hypoplasia of the clavicles 0.3163198652561089 0.1603237841058296 0.8726260241976092 1.0 1.0 14 O75844,O75431 2 +Abnormal urine ph 0.3013577323025044 0.1574925945651068 0.8748566437459107 1.0 1.0 44 O43772,P00846,O96000,P35914,Q9BQT8,P23786,P03886 7 +Hypothalamic hypothyroidism 0.5072697899838379 0.15515680183001 0.876697702939268 1.0 1.0 3 Q99496,Q969G3 2 +Neuralgia 0.5072697899838379 0.15515680183001 0.876697702939268 1.0 1.0 3 Q99496,Q969G3 2 +Brain stem compression 0.5072697899838379 0.15515680183001 0.876697702939268 1.0 1.0 3 Q99496,Q969G3 2 +Decreased circulating follicle stimulating hormone concentration 0.5072697899838379 0.15515680183001 0.876697702939268 1.0 1.0 3 Q99496,Q969G3 2 +Progressive pulmonary function impairment 0.5072697899838379 0.15515680183001 0.876697702939268 1.0 1.0 3 Q99496,Q969G3 2 +Intracranial meningioma 0.5072697899838379 0.15515680183001 0.876697702939268 1.0 1.0 3 Q99496,Q969G3 2 +Visual acuity test abnormality 0.5072697899838379 0.15515680183001 0.876697702939268 1.0 1.0 3 Q99496,Q969G3 2 +Ear pain 0.5072697899838379 0.15515680183001 0.876697702939268 1.0 1.0 3 Q99496,Q969G3 2 +Transient global amnesia 0.5072697899838379 0.15515680183001 0.876697702939268 1.0 1.0 3 Q99496,Q969G3 2 +Decreased pulmonary function 0.5072697899838379 0.15515680183001 0.876697702939268 1.0 1.0 3 Q99496,Q969G3 2 +Limb muscle weakness 0.3243064207382747 0.1543346032756104 0.8773459146907077 1.0 1.0 79 P00846,Q99720,O75298,P07196,Q13510,Q9BQT8,P50402,Q13126,Q9NR77,O43819,P50336,O00400,Q8IY17 13 +Amenorrhea 0.2868989631636677 0.1523724281099711 0.8788932023124898 1.0 1.0 33 P16435,Q9BUK6,Q96RR1,Q9NR50,Q16740 5 +Sepsis 0.3034925971958009 0.1513061101876812 0.8797342495427594 1.0 1.0 18 P42892 1 +Ectropion of lower eyelids 0.4987080103359197 0.1494056589052544 0.8812335466892613 1.0 1.0 2 Q99496 1 +Spinocerebellar tract degeneration 0.4964470284237738 0.1462642665164911 0.8837127736311539 1.0 1.0 2 O00754 1 +Abnormality of the spinocerebellar tracts 0.4964470284237738 0.1462642665164911 0.8837127736311539 1.0 1.0 2 O00754 1 +Abnormality of epiphysis morphology 0.3088744652860474 0.1453270184203962 0.8844526835526572 1.0 1.0 53 Q9Y2D4,P16435,Q9Y619,Q96HY6,Q5JRA6,P16278,Q6NUQ1,P38435,O95202,O75381,Q9NR45,Q9HC07,O95831,Q9NUQ7 14 +Tongue atrophy 0.3981326191524147 0.1428801527296925 0.886384833561312 1.0 1.0 4 P07196 1 +Decreased number of peripheral myelinated nerve fibers 0.3065301484575648 0.1423143909752725 0.8868316798687794 1.0 1.0 15 Q9NR77,P07196,O15269 3 +Abnormal heart valve morphology 0.3214723797238507 0.1412749479763994 0.8876527397221068 1.0 1.0 74 O75844,P21964,P16278,Q92766,P37268,Q6PGP7,O95202,O15294,P06280,Q96PU5,Q8NCH0,Q9UHX1,O75431,Q9BXW9 14 +Mild microcephaly 0.3513426075703583 0.1387879488714531 0.8896177172250033 1.0 1.0 7 Q9Y2V7,Q69YN2,Q05086,P31040,P21912,Q86W42 6 +Gastritis 0.3663110248949237 0.1372544250922581 0.8908296929252488 1.0 1.0 5 Q6PGP7,Q15477,P50851,P49327 4 +Abnormality of the lower urinary tract 0.2766655341120293 0.1368146481006943 0.8911773050132554 1.0 1.0 219 Q99720,O43681,Q9BRK0,P48449,P07196,P07602,O15294,Q71SY5,Q8NCH0,P50336,Q9NWM8,Q9UJS0,P46783,Q9UP83,P37268,Q92766,Q86XL3,Q9UBX3,Q9BXW9,P07437,P21964,Q9Y619,P50570,O95453,Q6PGP7,O75381,P61978,O43791,Q9UHX1,O75844,P16435,Q9UBB4,Q9BV10,O75298,Q96RR1,O95202,O75787,Q9NR77,Q08J23,P20700,Q8IY17 41 +Oligohydramnios 0.2832905338617235 0.1358878301120984 0.8919099563947954 1.0 1.0 32 P16435,Q9NSD9,Q9UP83,P23786,P49366,Q9UHX1 6 +Oral cavity bleeding 0.3378640776699078 0.1340926185502158 0.8933293364734383 1.0 1.0 8 P40763,Q02241,Q6UN15,Q6W2J9,Q9BZK7,P10644,P06748 7 +Abnormality of the upper respiratory tract 0.3227464054070215 0.1336116875697087 0.8937096417184418 1.0 1.0 92 Q03518,Q96HY6,P07602,P15586,Q92766,Q13510,Q92804,P28070,P21964,P16278,Q13277,O95453,Q13432,Q9NVR5,Q9UHX1,P16435,Q15165,Q9BV10,P54802 19 +Large beaked nose 0.3646944713870012 0.1335276257478096 0.8937761177013805 1.0 1.0 5 O14802,Q9Y3Z3,Q12797,P55265 4 +Abnormal conjunctiva morphology 0.2967926660219531 0.1334570579436455 0.8938319232082146 1.0 1.0 26 Q9NZ08,Q13510,P06280,P10619,P28070 5 +Inverted nipples 0.3286859874566561 0.1329676530949611 0.8942189623889387 1.0 1.0 10 Q9BV10,Q96AA3,P61978,P83436,O60762 5 +Primary hyperparathyroidism 0.4861111111111225 0.1326966692881258 0.8944332770938661 1.0 1.0 2 Q6P1J9 1 +Hyperparathyroidism 0.4861111111111225 0.1326966692881258 0.8944332770938661 1.0 1.0 2 Q6P1J9 1 +Macular atrophy 0.3521607397731181 0.1317832782438229 0.8951557132159818 1.0 1.0 6 P04439,Q8WWY3 2 +Abnormal pattern of respiration 0.2583654791025431 0.1293364082036463 0.897091463778739 1.0 1.0 178 P00846,O75306,O14678,P07602,Q9BQP7,O95831,Q9BZK7,P03886,Q9NZJ7,Q03001,P04114,O75880,Q7KZN9,P51571,Q13510,Q92804,O60762,Q96A33,O43772,Q9NSD9,P22695,Q9Y619,O95453,P35914,P61978,O43791,Q9UHX1,Q86Y39,O75844,Q10713,Q15165,Q8N3U4,Q96RR1,Q96CU9,P06280,P23786,O43819,O75648,Q9P0J0,O75380 40 +Stillbirth 0.3232697091569204 0.1268893153524033 0.8990280033959852 1.0 1.0 11 O75844,P16435 2 +Athetosis 0.3032440536090138 0.1265767161283575 0.8992754265266103 1.0 1.0 15 O00584,Q96CU9,O14949,Q96RR1 4 +Abnormal meningeal morphology 0.2991763680810877 0.1248210506712825 0.9006652217002316 1.0 1.0 22 P21964,Q92766,Q9UHX1,Q10713 4 +Pancytopenia 0.285833039616103 0.1237422230720175 0.9015193793780704 1.0 1.0 35 Q14108 1 +Abnormality of fibula morphology 0.3172056038110802 0.1221667414954026 0.9027669655620492 1.0 1.0 12 P16435,Q9NR45,O75431 3 +Impaired t cell function 0.321914678585607 0.1217226876107738 0.9031186447279312 1.0 1.0 11 P21964,Q96DF8 2 +Nyctalopia 0.2867147890327949 0.1199573377669552 0.9045169433779292 1.0 1.0 30 P38435,O75381,Q13432,Q10713,Q13586 5 +Disproportionate short limb short stature 0.2984855564784604 0.1198148656670761 0.9046298056786608 1.0 1.0 20 Q9BV10,Q7LGA3,Q15392,O75718,Q32P28 5 +Abnormality of the gingiva 0.2985649183008047 0.1183696127423759 0.9057748019968904 1.0 1.0 46 Q14108,P16278,O95453,Q15392,Q9BZK7,O00203 6 +Spinal rigidity 0.3071548585736293 0.1182836217032935 0.9058429342794336 1.0 1.0 14 Q9BQP7,P50402,Q8WXH0 3 +Abnormality of female external genitalia 0.2850143547427602 0.1176501451502553 0.9063448707331077 1.0 1.0 35 Q9Y619,Q9UNW1,O75381,Q15392,Q08J23 5 +Abnormality of the hepatic vasculature 0.3240644525061765 0.116369639463219 0.907359596088878 1.0 1.0 10 Q9NSD9 1 +Abnormal leukocyte physiology 0.3123571072628284 0.1157721147165673 0.9078331511107562 1.0 1.0 62 P21964,Q9UJW0,Q14108,Q9BV10,P02786,Q92766,Q6PGP7,P09601,O75787,P28070,O00203,Q96DF8,P14174,Q9UJS0 14 +Hypohidrosis 0.3203034880412532 0.1156335173538526 0.9079429980718484 1.0 1.0 11 Q13586,P06280 2 +Abnormal urine potassium concentration 0.4712532299741663 0.1154178292090667 0.9081139477349168 1.0 1.0 2 P05023 1 +Progressive spasticity 0.3064446509028301 0.1151178605372985 0.9083517033568111 1.0 1.0 14 O43681 1 +Hypometric saccades 0.4785137318255094 0.113852285461343 0.9093548902139772 1.0 1.0 3 P49959,P04062 2 +Tachycardia 0.2970231059076986 0.1125641012151393 0.9103761471892752 1.0 1.0 22 O43772,P04899,P42892,P23786,Q8NFF5 5 +Abnormal talus morphology 0.2959784839981092 0.1118413361880443 0.9109492115730748 1.0 1.0 18 Q9UHX1 1 +Calcific stippling 0.4673772609819148 0.1113282716603537 0.9113560372064922 1.0 1.0 2 O15228 1 +Leukoencephalopathy 0.3206339395644098 0.1111461752672642 0.9115004329812396 1.0 1.0 90 O43681,O75306,P07602,Q9NPL8,O00584,O95831,P03886,Q9NZJ7,O43676,O75503,P35914,O75380,Q9NR50,Q9UHX1,Q86Y39,O96000,Q9Y375,O95202,Q96CU9,O75648,Q96TA2,P20700,Q8TB37 23 +Cutaneous melanoma 0.3804137039431177 0.1102495651584695 0.9122114545116952 1.0 1.0 4 Q99496,P42771,P11802 3 +Nasogastric tube feeding 0.2942373531555641 0.1094264176033567 0.912864281340739 1.0 1.0 25 Q9UBB6,Q96N66,Q08J23,Q71SY5,Q9HA77 5 +Lissencephaly 0.3004988151606541 0.1088850871664952 0.9132936350290632 1.0 1.0 49 Q9Y320,O43505,Q9H936,Q9BV10,Q15392,Q16625,O43175,Q6ZXV5,P57740,Q86XL3,Q9BVA1,P23786,P20700,Q9Y487 14 +Recurrent lower respiratory tract infections 0.2912858966780361 0.1085603106568415 0.9135512421439008 1.0 1.0 27 P78318,Q13277,Q13432,O00203,Q71SY5,P20700 6 +Exaggerated cupid s bow 0.3293615342428074 0.1074613618696694 0.9144229765358184 1.0 1.0 8 Q71SY5 1 +Abnormality of the musculature of the hand 0.2822503491610111 0.1074005764892949 0.9144711971806964 1.0 1.0 34 Q13586,Q9NR77,P07196,Q9BQT8 4 +Moderate albuminuria 0.4731269037102435 0.1071186949007075 0.9146948161142034 1.0 1.0 3 Q5JRA6 1 +Renal cell carcinoma 0.2955624086849822 0.1069674708869849 0.9148147861257374 1.0 1.0 23 Q14145,Q9UNW1 2 +Chronic mucocutaneous candidiasis 0.3523005754268946 0.1063807691890065 0.9152802504523764 1.0 1.0 5 O00203,P02786 2 +Involuntary movements 0.3103542002902886 0.1048904434642308 0.9164627421478212 1.0 1.0 322 P61457,P00846,Q99720,O43681,Q14108,Q96F07,Q9BWD1,Q9BRK0,P07196,P07602,P00403,Q9NPL8,O00584,O95831,Q71SY5,O00400,P03886,Q9HA77,O75027,Q9UJS0,Q86VD7,P50897,O14949,Q13510,Q9BQT8,Q9H6K4,Q9UBX3,O60762,Q03252,Q5XKP0,P13073,Q9Y619,P61916,Q96N66,O75503,P35914,O43791,Q6DKK2,Q9UHX1,O14653,Q9NUQ7,Q10713,Q9UBB6,Q9UBB4,Q9BUK6,Q9UNW1,O75298,Q6P4A7,O95202,Q96RR1,Q96IX5,Q96CU9,P06280,Q8NC96,O75787,Q9NR77,O43819,Q08J23,P20700,Q9P0J0,O14773,P41440,Q8IY17 63 +Abnormal t cell subset distribution 0.3203451539846629 0.1033476137544255 0.9176870875889608 1.0 1.0 10 Q13432,O00203 2 +Increased serum testosterone level 0.4576873385012939 0.101832548570314 0.9188895899112276 1.0 1.0 2 P24468 1 +Dyspnea 0.3186922586113499 0.1017860596070196 0.9189264909984995 1.0 1.0 97 P00846,O75306,P07602,Q9BQP7,O95831,Q9BZK7,P03886,Q9NZJ7,P04114,Q13510,Q92804,O60762,Q9Y619,O95453,Q9UHX1,O75844,Q15165,Q96RR1,P06280,P23786,O43819,O75648 22 +Spastic paraplegia 0.3075463960717439 0.1003167781191394 0.9200928376707056 1.0 1.0 58 P00846,O75298,Q9BRK0,O95831,Q9P0J0,P49902,Q7KZN9,Q8IY17 8 +Diffuse alveolar hemorrhage 0.3377547719184717 0.0998715879702974 0.9204462730648596 1.0 1.0 7 P40763,Q6UN15,Q6W2J9,Q9BZK7,P10644,P06748 6 +Metrorrhagia 0.3377547719184717 0.0998715879702974 0.9204462730648596 1.0 1.0 7 P40763,Q6UN15,Q6W2J9,Q9BZK7,P10644,P06748 6 +Addictive behavior 0.3377547719184717 0.0998715879702974 0.9204462730648596 1.0 1.0 7 P40763,Q6UN15,Q6W2J9,Q9BZK7,P10644,P06748 6 +Joint laxity 0.3178343704613275 0.0998629819145305 0.9204531055469972 1.0 1.0 77 Q32P28,Q9NSD9,Q9Y619,Q96HY6,P16278,Q9BUK6,Q9NR45,Q9HC07,Q9BZK7,Q8NCH0,Q96A33,Q9Y487,Q9UHX1 13 +Megalencephaly 0.4541343669250664 0.098604540878869 0.9214522644948224 1.0 1.0 2 O00459 1 +Focal cortical dysplasia 0.4541343669250652 0.0986045408788679 0.9214522644948232 1.0 1.0 2 Q8WUM0 1 +Lactose intolerance 0.4541343669250608 0.0986045408788639 0.9214522644948264 1.0 1.0 2 Q14566 1 +Butterfly vertebrae 0.3733522263033065 0.0985014593376961 0.9215341132124956 1.0 1.0 4 Q8N3U4 1 +Iris hypopigmentation 0.3719091300142594 0.0961885727108833 0.9233708063868756 1.0 1.0 4 O00203 1 +Osteomalacia 0.3381095281208884 0.09589921119386 0.923600621070234 1.0 1.0 6 O43175,P35670 2 +Beaking of vertebral bodies 0.3181246645889291 0.0957191019242348 0.9237436694179388 1.0 1.0 10 Q9Y2D4,P04066,P16278,Q6NUQ1 4 +Abnormal duodenum morphology 0.3059680975756038 0.0923915593129239 0.9263869454378236 1.0 1.0 13 Q8NCH0,Q9BXW9 2 +Increased muscle glycogen content 0.4601507142023499 0.0921635729625319 0.92656807939113 1.0 1.0 3 Q9BUK6 1 +Abnormal circulating serine concentration 0.4600676315033748 0.092073491765796 0.9266396494765006 1.0 1.0 3 Q9UJS0 1 +Gastrointestinal hemorrhage 0.2848017838242624 0.0912161509956717 0.9273208418147704 1.0 1.0 29 P21964,Q9UGP8,Q9NZ08,Q9UHX1,Q9UJS0 5 +Facial erythema 0.4437984496124039 0.08995686394575 0.9283214933785242 1.0 1.0 2 Q9H1A4 1 +Sudden loss of visual acuity 0.4437984496123991 0.089956863945746 0.9283214933785272 1.0 1.0 2 P35222 1 +Abnormal size of the clitoris 0.2905529535469766 0.089584436602261 0.9286174524653406 1.0 1.0 17 O75381,Q9Y619,Q9UNW1 3 +Gastroparesis 0.3201200731003403 0.0889539880646739 0.9291184772976148 1.0 1.0 9 P61978,O43464,Q96RR1 3 +Pneumonia 0.3008704021225744 0.0887112214732931 0.9293114142533891 1.0 1.0 52 Q8N3U4,P78318,P16278,Q13510,Q13432,Q71SY5,O00203,P20700 8 +Decreased specific antibody response to vaccination 0.3661926308985153 0.087318860005492 0.9304180631610665 1.0 1.0 4 Q9BV10,P17812,P50851 3 +Noncompaction cardiomyopathy 0.3658694246929562 0.086831274528439 0.9308056280214676 1.0 1.0 4 Q96DA6,Q15233,P21912 3 +Back pain 0.2919922634742183 0.0866313219077116 0.9309645682052444 1.0 1.0 23 Q9UGP8,P50336,P50402,P35670 4 +Juvenile aseptic necrosis 0.3338339139777567 0.0856838399805324 0.931717748706373 1.0 1.0 6 Q9Y619,Q9NUQ7 2 +Abnormal thyroid hormone level 0.4379844961240413 0.0855600610801979 0.9318161486272296 1.0 1.0 2 O14654 1 +Protruding tongue 0.3040245040553835 0.0844837029757224 0.9326718596555614 1.0 1.0 13 Q10713,Q05086,P83436,P20700 4 +Testicular atrophy 0.3642533936651603 0.0844155890154823 0.9327260132832288 1.0 1.0 4 P00492,Q9NX24,O76024 3 +Peritoneal abscess 0.3642533936651602 0.0844155890154823 0.9327260132832288 1.0 1.0 4 Q5HYI8,P42771,P38398 3 +Functional intestinal obstruction 0.3642533936651602 0.0844155890154823 0.9327260132832288 1.0 1.0 4 Q5HYI8,P42771,P38398 3 +Extrahepatic cholestasis 0.3642533936651602 0.0844155890154823 0.9327260132832288 1.0 1.0 4 Q5HYI8,P42771,P38398 3 +Intestinal polyp 0.2913991195024695 0.0820871340067668 0.9345774241695288 1.0 1.0 20 P42892 1 +Abnormal muscle fiber protein expression 0.3399118362536645 0.0818004208242445 0.9348054214280046 1.0 1.0 5 P50402 1 +Ventricular escape rhythm 0.3399118362536645 0.0818004208242445 0.9348054214280046 1.0 1.0 5 P50402 1 +Abnormal diaphysis morphology 0.3102235140757088 0.0817221661926062 0.9348676512420552 1.0 1.0 65 P16435,Q9Y619,Q9UP83,Q96HY6,P16278,Q9HC07,Q13126,Q9NR77,O75718,Q32P28,Q9Y487,O75431 12 +Delayed eruption of teeth 0.2999597778133041 0.0815933948485071 0.9349700539293448 1.0 1.0 52 Q9Y487,O75844 2 +Apneic episodes precipitated by illness fatigue stress 0.4302325581395365 0.0801948992164601 0.936082246933024 1.0 1.0 2 P53007 1 +Scaphocephaly 0.361021331609569 0.0796951308339776 0.9364797321686644 1.0 1.0 4 Q969X5,P51659,P40855 3 +Bowing of the legs 0.2977301468750102 0.0795137911259603 0.936623962612226 1.0 1.0 50 P16435,Q9Y619,Q9UP83,Q96HY6,P16278,Q13126,Q9NR77,O75718,Q32P28,O75431 10 +Abnormal b cell subset distribution 0.4276485788113657 0.0785280699350933 0.9374080025813878 1.0 1.0 2 P17812 1 +Quadriceps muscle weakness 0.3600517129928915 0.0783077366633419 0.9375832633959328 1.0 1.0 4 P12235,O95140,Q96RR1 3 +Abnormality of the knee 0.3172177911444028 0.0780376218757545 0.9377981262998 1.0 1.0 88 Q9Y2D4,Q96HY6,O95831,Q9UP83,Q7LGA3,P37268,Q92766,Q13510,Q86XL3,O60762,O95817,P21964,Q9Y619,Q5JRA6,P16278,Q96PU5,Q9NUQ7,O75431,P23786,Q9NR77,P49902 21 +Decreased specific antibody response to protein vaccine 0.4452029900104893 0.0770851424276501 0.9385558124543372 1.0 1.0 3 Q9BV10 1 +Abnormality of the bladder 0.3024251667550552 0.0764144541384219 0.9390893704887664 1.0 1.0 122 Q99720,O43681,Q9BRK0,P07196,P07602,P50336,Q8NCH0,Q9NWM8,Q9UJS0,Q9UP83,Q92766,Q86XL3,P21964,P50570,P61978,O43791,Q9UHX1,P16435,Q9UBB4,O75298,Q96RR1,Q9NR77,P20700 23 +Long penis 0.4439418416801306 0.0759147762753279 0.9394869010161856 1.0 1.0 3 O14802,Q56NI9 2 +Abnormal saccadic eye movements 0.2874014085100173 0.0754686313231724 0.9398418549176976 1.0 1.0 26 Q10713,O43819 2 +Bilateral tonic clonic seizure with generalized onset 0.3119471195422167 0.0750835041120263 0.94014827258475 1.0 1.0 10 Q05086,Q13510 2 +Long hallux 0.4425991986479814 0.0746857939848139 0.9404647108606814 1.0 1.0 3 O60762 1 +Abnormal lactate dehydrogenase level 0.2918494985513016 0.0744051023132017 0.9406880490004934 1.0 1.0 15 P23786,P41440,Q9UJS0 3 +Impaired tactile sensation 0.3179756072446213 0.0740632433813386 0.9409600624354612 1.0 1.0 8 Q9NR77 1 +Tibial torsion 0.4156976744186014 0.0715656675929121 0.9429475632813566 1.0 1.0 2 Q9Y5S9 1 +Abnormality of the peripheral nervous system 0.3157901704967251 0.0705607745927322 0.9437473299029808 1.0 1.0 96 Q99720,O43681,P07196,P07602,O95831,Q71SY5,P50336,O15269,Q92766,Q9BXW9,P21964,Q9Y619,P50570,P42892,Q8N3U4,Q9UBB4,P06280,Q9NR77,P20700,Q10713,P41440 21 +Conspicuously happy disposition 0.4127906976744188 0.0700490211211542 0.9441546422202318 1.0 1.0 2 P55795 1 +Fatigue 0.314570560206552 0.0681029384519432 0.9457036912435282 1.0 1.0 78 Q15165,Q9NZ08,P07602,P06280,P35914,Q70HW3,Q53H12,Q13423 8 +External ear malformation 0.2872167713794313 0.0680575332433713 0.945739835498453 1.0 1.0 18 P07437,O75381,Q8NCH0 3 +Broad alveolar ridges 0.408268733850128 0.0678197165232905 0.9459291483810836 1.0 1.0 2 Q9UBM7 1 +Nephrolithiasis 0.2886026705563869 0.0676609688093677 0.9460555204529002 1.0 1.0 20 Q4J6C6,Q9BQP7,Q8NCH0 3 +Abnormal blood phosphate concentration 0.325679172056914 0.067130894543796 0.9464774990733652 1.0 1.0 6 Q08426,Q6P1J9,P10644,P53680,P51798 5 +Increased sulfur amino acid level in urine 0.3317659223412593 0.0670417327867145 0.946548479955542 1.0 1.0 5 Q4J6C6 1 +2 3 toe syndactyly 0.2751691822845223 0.0665888076457609 0.9469090561740277 1.0 1.0 33 P37268,Q9UHX1,Q71SY5 3 +Abnormal blood ion concentration 0.3076865247750659 0.0660349170356275 0.9473500263370898 1.0 1.0 64 P61457,P21964,Q9NSD9,Q9BV10,Q4J6C6,Q92766,Q6PGP7,O43819,P50336,Q9Y487,Q96DF8,Q13423 12 +Secundum atrial septal defect 0.3500323206205578 0.0647406764766188 0.9483804755931564 1.0 1.0 4 P62913,P34897,P24468 3 +Heterophoria 0.3985788113695128 0.0635471342136404 0.9493308273857656 1.0 1.0 2 Q9ULH0 1 +Pancreatic fibrosis 0.3950258397932767 0.0621429023509223 0.9504490318631608 1.0 1.0 2 Q96J42 1 +Absent earlobe 0.427463651050082 0.0620131190418175 0.9505523846254842 1.0 1.0 3 O14802,Q56NI9 2 +Abnormal sharpey fiber morphology 0.3280048624387529 0.0606028999595491 0.9516754639377434 1.0 1.0 5 P35670 1 +Chondrocalcinosis 0.3280048624387529 0.0606028999595491 0.9516754639377434 1.0 1.0 5 P35670 1 +Generalized muscle weakness 0.2799664327208836 0.059770763331458 0.9523382114125922 1.0 1.0 29 Q15165 1 +Gynecomastia 0.2868507271557362 0.0587616815454622 0.9531419293922484 1.0 1.0 20 Q8IY17 1 +Vomiting 0.313320052118842 0.05816426494038 0.953617784957526 1.0 1.0 101 P00846,O75306,P07602,P00403,Q9NPL8,P50336,P03886,Q9NZJ7,Q9Y584,Q16836,Q9UJS0,O43676,P51571,Q13423,Q9NSD9,P22695,Q9Y619,Q13277,P35914,P61978,O75380,Q86Y39,O96000,Q8N3U4,Q96CU9,P06280,P23786,O75648,P11117,Q9Y375,Q8TB37 31 +Abnormal cns myelination 0.2847395113543718 0.0576263134598147 0.9540462893866604 1.0 1.0 137 Q99720,O43681,P07602,Q9NPL8,O00584,O95831,P03886,Q9Y584,Q5BJH7,Q7KZN9,O43676,P51572,P51648,O75746,Q9NR50,O96000,Q9UBB6,O75787,O43819,P20700,Q9P0J0,Q8TB37 22 +Enlarged cerebellum 0.3775839793281635 0.0563798043798796 0.9550392451313224 1.0 1.0 2 O60315 1 +Functional abnormality of the inner ear 0.2781049892180338 0.056175071210138 0.9552023400885564 1.0 1.0 234 P00846,O43681,O95470,P07196,P07602,P00403,Q9NPL8,O00584,O95831,Q9BZK7,Q8WWY3,P03886,P33527,Q16740,Q9NWM8,O15269,O43676,Q9UP83,Q9H061,Q13510,Q5XKP0,Q5JRA6,P78318,O75381,Q9NZ08,P61978,P51572,P42892,Q86Y39,O75844,O96000,P42167,O00303,Q8N3U4,Q9BV10,Q9Y375,Q96RR1,O95202,Q96CU9,P06280,Q9NR77,P20700,Q8TB37,P41440,Q8IY17 45 +Broad nasal tip 0.2965845433253301 0.0555176667043133 0.9557260556609392 1.0 1.0 52 Q9Y487,Q9UHX1,P16278 3 +Limited knee extension 0.3714470284237717 0.0547530207987104 0.9563352281909994 1.0 1.0 2 Q04656 1 +Hypoplasia of the pons 0.2831817407129631 0.0545416405326648 0.9565036335964752 1.0 1.0 17 Q9BVA1,Q9Y3B2,Q9UNW1 3 +Anterior pituitary dysgenesis 0.368540051679584 0.0540473824943536 0.9568974136114684 1.0 1.0 2 Q15233 1 +Progressive leukoencephalopathy 0.3656330749353986 0.0533812717247291 0.9574281269333133 1.0 1.0 2 Q5JTZ9 1 +Congenital craniofacial dysostosis 0.3636950904392728 0.0529583715691026 0.9577650758166768 1.0 1.0 2 Q6NUK1 1 +Aplasia hypoplasia of the nasal bone 0.3636950904392728 0.0529583715691026 0.9577650758166768 1.0 1.0 2 Q6NUK1 1 +Paraplegia 0.3022643585817918 0.0515987651627063 0.9588484032884508 1.0 1.0 59 P00846,O75298,Q9BRK0,O95831,Q9P0J0,P49902,Q7KZN9,Q8IY17 8 +Abnormality of upper limb metaphysis 0.3475452196382434 0.0500291022389561 0.960099197120134 1.0 1.0 2 Q9H1A4 1 +Absent thumbnail 0.4084006462035431 0.0489554109890953 0.96095483017892 1.0 1.0 3 O14936,Q9H936 2 +Seborrheic dermatitis 0.31740458014146 0.0480631448959844 0.9616659183542108 1.0 1.0 7 P21964 1 +Craniofacial osteosclerosis 0.3252583979328152 0.0473992129988879 0.9621950562528852 1.0 1.0 2 P51798 1 +Hashimoto thyroiditis 0.3175064599483163 0.046775857486612 0.9626918709009176 1.0 1.0 2 Q96J02 1 +Gonadal neoplasm 0.2824472288697078 0.0462154470779574 0.96313853064211 1.0 1.0 26 Q13423 1 +Reduced pancreatic beta cells 0.296834625322989 0.0456363841238795 0.963600069033699 1.0 1.0 2 P40763 1 +Aplasia involving bones of the extremities 0.3991314948252352 0.04367576705247 0.965162855869993 1.0 1.0 3 Q9BXW9 1 +Abnormal palmar dermatoglyphics 0.3002048458005719 0.0417839980877546 0.966670891548178 1.0 1.0 58 O95202,Q9BZK7,Q71SY5,Q8NCH0,Q9Y487,Q9UHX1,O75431,Q8IY17 8 +Abnormality of the gallbladder 0.2785038693169072 0.0412264607828388 0.967115358946712 1.0 1.0 38 O43681,O95202,P22830,P07602,Q71SY5,Q96A33 6 +Arthropathy 0.3149017535923986 0.04000735976382 0.968087258749194 1.0 1.0 5 O15269 1 +Flared metaphysis 0.3029213799630152 0.0382523584560942 0.969486475404836 1.0 1.0 9 Q9NR45,Q96HY6 2 +Abnormality of the liver 0.3022480551625288 0.0373068113873474 0.9702403745733884 1.0 1.0 307 P00846,Q9UJW0,O43681,Q14108,Q96HY6,Q6NUQ1,O75306,Q9NRW7,P07602,P31751,Q9NPL8,P35670,Q71SY5,P50336,P03886,P04114,O75880,P15586,Q9NZJ7,Q9HA77,Q7KZN9,Q8N511,O43676,Q9UJS0,Q9UP83,Q9BT22,Q92766,Q9UGP8,Q13510,P28070,Q9NVI7,O15118,P33991,O60762,Q96A33,Q03252,Q5XKP0,Q9BXW9,O43772,P21964,Q9NSD9,Q9Y619,P61916,P16278,O95453,Q6PGP7,O75381,P09601,Q16625,P35914,O00203,O75380,O43791,P20674,O75431,P50416,Q86Y39,O96000,Q96RR1,O95202,P22830,Q9HC07,Q96CU9,P83436,O75787,P23786,P10619,P54802,O75648,Q9Y375,Q10713,P14174,Q8TB37,Q8IY17 74 +Severe intrauterine growth retardation 0.3254686489980628 0.0372136929422994 0.9703146207861106 1.0 1.0 4 O14802,Q92979,Q56NI9 3 +Hallucinations 0.2854778553818656 0.0370763851444426 0.9704241010040736 1.0 1.0 44 O43681,P50897,P07602,O75503,Q6DKK2,Q9UJS0 6 +Septate vagina 0.374798061389337 0.0327320473886073 0.973888267456542 1.0 1.0 3 O60315,Q9UBM7 2 +Gastric ulcer 0.3741518578352221 0.0324934759507386 0.9740785187212252 1.0 1.0 3 P04062,O76024 2 +Abnormal drinking behavior 0.3741518578352216 0.0324934759507383 0.9740785187212252 1.0 1.0 3 Q6P1J9,O76024 2 +Talipes valgus 0.3183581124757618 0.030684071053639 0.9755214946392892 1.0 1.0 4 O00754,Q15233,P49589 3 +Abnormal female reproductive system physiology 0.3018634201911462 0.0302876736595897 0.9758376270588328 1.0 1.0 62 O75844,P16435,Q9BUK6,O75298,Q96RR1,P31751,P35670,P57740,Q9BZK7,Q9NR50,Q16740,Q9UJS0 12 +Neonatal alloimmune thrombocytopenia 0.3644588045234194 0.0292030013926472 0.9767026874908136 1.0 1.0 3 Q9Y3Z3,P55265 2 +Chilblains 0.3644588045234194 0.0292030013926472 0.9767026874908136 1.0 1.0 3 Q9Y3Z3,P55265 2 +Moyamoya phenomenon 0.3644588045234194 0.0292030013926472 0.9767026874908136 1.0 1.0 3 Q9Y3Z3,P55265 2 +Degeneration of the striatum 0.3644588045234194 0.0292030013926472 0.9767026874908136 1.0 1.0 3 Q9Y3Z3,P55265 2 +Chronic lymphatic leukemia 0.3644588045234194 0.0292030013926472 0.9767026874908136 1.0 1.0 3 Q9Y3Z3,P55265 2 +Chronic leukemia 0.3644588045234194 0.0292030013926472 0.9767026874908136 1.0 1.0 3 Q9Y3Z3,P55265 2 +Csf lymphocytic pleiocytosis 0.3644588045234194 0.0292030013926472 0.9767026874908136 1.0 1.0 3 Q9Y3Z3,P55265 2 +Csf pleocytosis 0.3644588045234194 0.0292030013926472 0.9767026874908136 1.0 1.0 3 Q9Y3Z3,P55265 2 +Increased circulating androgen concentration 0.3641357027463545 0.0291022749586051 0.9767830214131636 1.0 1.0 3 O14802,P24468 2 +Abnormality of the nasal bone 0.3638126009693014 0.0290021047067906 0.9768629119883792 1.0 1.0 3 Q6NUK1,P35222 2 +Bacterial endocarditis 0.363812600969296 0.029002104706789 0.9768629119883804 1.0 1.0 3 P04062,P24468 2 +Polygenic inheritance 0.3068218558034195 0.0287078275245086 0.9770976134802358 1.0 1.0 5 O60934,P50454,P04637,Q07812 4 +Abnormal oral mucosa morphology 0.297626501655144 0.0283433538312568 0.9773883031187952 1.0 1.0 57 Q14108,P16278,O95453,Q9NZ08,Q15392,Q9BZK7,O00203,O75431 8 +Long palpebral fissure 0.2780326785524272 0.0276538531082839 0.977938229497542 1.0 1.0 27 Q5KU26,O43791,P20700 3 +Scleral staphyloma 0.3138332255979338 0.0268447636014312 0.9785835498780976 1.0 1.0 4 P40939,Q969N2,P36404 3 +Renal dysplasia 0.2912942738252261 0.0259616175048301 0.9792879529181217 1.0 1.0 12 O75306,O43819,O43505 3 +Limb joint contracture 0.3089996599378304 0.0242643425370515 0.9806417552848932 1.0 1.0 104 O75844,Q99720,Q9Y619,P37268,P07196,Q15392,P50402,P49902,Q86XL3,Q9NR77,Q08J23,Q8IZA0,P23786,Q71SY5,P42892 15 +Central hypothyroidism 0.2953367875647645 0.0240667393470728 0.980799373789862 1.0 1.0 10 Q8N3U4,Q99496,Q9NW13,P35222,Q14683,O14654,Q969G3,Q12824,O00170 9 +Antineutrophil antibody positivity 0.3318255250403913 0.0215098671413866 0.9828389324442312 1.0 1.0 3 P49327,Q96J02 2 +Proximal femoral metaphyseal abnormality 0.3318255250403858 0.0215098671413858 0.982838932444232 1.0 1.0 3 Q9NUQ7,Q9Y3A5 2 +Recurrent hand flapping 0.3214660582920899 0.0199382058468265 0.9840926673374568 1.0 1.0 3 Q05086 1 +Semilobar holoprosencephaly 0.3048188935715656 0.0198971349606196 0.9841254306639844 1.0 1.0 4 Q8N3U4 1 +Limb girdle muscle weakness 0.2793125855011636 0.019888779054923 0.9841320963930872 1.0 1.0 24 O14979,Q96RR1,P07602,Q13126,O60313,Q9NZJ7 6 +Aplasia hypoplasia of the sacrum 0.3050080775444296 0.0180795405456376 0.985575399564184 1.0 1.0 3 Q8TAA9,P04066 2 +Increased vertebral height 0.2966074313408777 0.0173777487829143 0.9861352603746768 1.0 1.0 3 Q96J02,O00754 2 +Corneal scarring 0.2714054927302128 0.0160027640183864 0.9872321866101536 1.0 1.0 3 Q86XI2,Q03001 2 +Polycystic kidney dysplasia 0.2819953671956531 0.0150033221266555 0.988029530007558 1.0 1.0 14 P23786,P21964,Q92766 3 +Telangiectasia of the skin 0.2733110878125278 0.0105629523175885 0.9915721401540184 1.0 1.0 17 Q8IZA0,P06280 2 +Widened subarachnoid space 0.2736355501447899 0.010162022347218 0.9918920188102688 1.0 1.0 28 O95831,P03886 2 +Abnormality of humoral immunity 0.2933261817171433 0.0092829907336193 0.9925933513923756 1.0 1.0 55 Q9UJW0,Q14108,Q9BV10,P02786,Q6PGP7,P14174,P09601,O75787,P28070,Q03252,Q9UJS0 11 +Iris coloboma 0.2696545013674311 0.007434548893311 0.9940681428663228 1.0 1.0 30 Q10713,O95202,O43505,Q9UHX1,Q8IY17 5 +Delayed ability to stand 0.2828054298642557 0.0065195054501613 0.9947982241066105 1.0 1.0 4 P21912,Q9ULH0,P10253 3 +Abnormality of vitamin metabolism 0.2767658192894585 0.0064967686525605 0.994816365062186 1.0 1.0 24 Q9NSD9,P41440 2 +Feeding difficulties in infancy 0.2432671660884346 0.0048632355853914 0.996119714706352 1.0 1.0 161 Q99720,O43681,O75306,P07602,Q9NPL8,O95831,Q9NZJ7,Q9Y584,Q9Y487,O75880,Q5BJH7,Q9UP83,P37268,Q92766,Q9UGP8,Q9NVI7,O60762,P21964,P22695,Q9Y619,O75381,P61978,O43791,Q9UHX1,P50416,Q8N3U4,Q9BV10,Q9BUF5,Q05086,P23786,O43819,O75648,Q10713 33 +Parkinsonism with favorable response to dopaminergic medication 0.2871536477885263 0.004424752988147 0.9964695694254482 1.0 1.0 11 P07602,Q9NZJ7 2 +Acute hepatic failure 0.2838068671924867 0.001570546622636 0.9987468856129365 1.0 1.0 12 Q16836,O75648,P35670,Q6NUQ1 4 +Stomatitis 0.2779568044955984 0.0002393103443804 0.999809057972801 1.0 1.0 14 Q9NZ08 1 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..711066c10f10af3cce96530e2322bf844cd4e9f6 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality of von willebrand factor", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Adult onset sensorineural hearing impairment", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonate wasting renal tubular acidosis", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid nasal tip", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Chin with horizontal crease", "Choanal stenosis", "Choking episodes", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clinodactyly of the 2nd finger", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Common atrium", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of renal pelvis", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid apraxia", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Imbalanced hemoglobin synthesis", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Inappropriate sexual behavior", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urinary potassium", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the 5th finger", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist movement", "Lingual dystonia", "Lipemia retinalis", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low self esteem", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Menorrhagia", "Mental deterioration", "Mesomelia", "Metabolic acidosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Percussion myotonia", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Punctate opacification of the cornea", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal sodium wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Sex reversal", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASS", "ABAT", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADSL", "AFG3L2", "AGA", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANXA11", "AP1B1", "AP1S2", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APOB", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARL6IP1", "ASAH1", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATIC", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7A", "ATP7B", "ATRIP", "ATRX", "ATXN10", "AURKA", "B3GAT3", "B4GAT1", "BAG3", "BANF1", "BARD1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCKDHA", "BCKDHB", "BCOR", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRCA1", "BRD4", "BUB1B", "BUB3", "BUD23", "C19orf70", "C1QBP", "CAD", "CALR", "CAMK2G", "CANT1", "CAPN1", "CARS", "CARS2", "CASK", "CAST", "CBX2", "CCDC22", "CCDC47", "CCT5", "CD2AP", "CD3EAP", "CDC40", "CDC42", "CDC73", "CDH2", "CDK4", "CDK5", "CDKN2A", "CELF2", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHORDC1", "CHP1", "CHST14", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLCN7", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNP", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COQ9", "COX15", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2A1", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CUL3", "CUL4B", "CUL7", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DBT", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DIAPH1", "DIP2B", "DKC1", "DLAT", "DLD", "DLST", "DNAAF2", "DNAAF5", "DNAJB11", "DNAJB6", "DNAJC13", "DNAJC19", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOLK", "DPF2", "DPM1", "DPP9", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DYNC1H1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EHHADH", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF3F", "EIF4A3", "EIF4G1", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "EPB41", "EPRS", "ERAL1", "ERAP1", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ESCO2", "ESS2", "ETFA", "ETFB", "ETFDH", "EXOC2", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EZR", "FANCD2", "FANCI", "FAR1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD2", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALNT2", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GATC", "GBA", "GCDH", "GCLC", "GDAP1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLS", "GLUD1", "GM2A", "GNAI2", "GNAI3", "GNPAT", "GNS", "GOSR2", "GOT2", "GPAA1", "GPD2", "GPI", "GPT2", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUF1", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HCFC1", "HELLS", "HEXA", "HEXB", "HEXIM1", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-C", "HMGA1", "HMGB3", "HMGCL", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IFT81", "IGBP1", "IGF2BP2", "IGF2R", "IMPAD1", "INTS1", "INTS8", "IRF2BPL", "IRS4", "ISCU", "ITCH", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KIAA0319L", "KIDINS220", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KMT2A", "KMT2B", "L2HGDH", "LAMB1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDLR", "LEMD2", "LEMD3", "LETM1", "LIPA", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPAP1", "LRPPRC", "LRRC8A", "LSS", "MACF1", "MAGED2", "MAGT1", "MAN2B1", "MAPK1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MED12", "MED17", "MED23", "MED25", "MED27", "MESD", "MFN2", "MFSD8", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MOCS1", "MOGS", "MORC2", "MPDU1", "MPG", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MYH9", "MYO6", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEFL", "NEK9", "NELFA", "NEPRO", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP10", "NOP56", "NPC1", "NPC2", "NPM1", "NR2F2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCLN", "OGDH", "OGT", "OPA1", "OPA3", "ORC6", "OXCT1", "P3H1", "P4HB", "PABPN1", "PAFAH1B1", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDHA1", "PDHB", "PDHX", "PDK3", "PEPD", "PEX11B", "PEX14", "PEX19", "PEX3", "PFKM", "PFN1", "PGK1", "PGM1", "PHB", "PHF6", "PHGDH", "PHIP", "PI4KA", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PISD", "PITRM1", "PKN1", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPOX", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKAR1A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PTCD3", "PTDSS1", "PTPN1", "PTRH2", "PUF60", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QRSL1", "RAB11B", "RAB18", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RABL3", "RAC1", "RAD21", "RAD50", "RAD51C", "RAI1", "RALA", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RBPJ", "RDH11", "RDX", "REEP2", "REPS1", "RFC1", "RFC2", "RFT1", "RHOA", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNPC3", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS29", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RREB1", "RRP7A", "RSPRY1", "RSRC1", "RTN2", "SAMHD1", "SAR1B", "SARS", "SARS2", "SBDS", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SDHA", "SDHB", "SDHC", "SEC23A", "SEC23B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEPT9", "SERPINB6", "SERPINH1", "SETD2", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC27A4", "SLC2A1", "SLC33A1", "SLC35A3", "SLC37A4", "SLC44A1", "SLC5A6", "SLTM", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPOP", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SRCAP", "SRP54", "SRP72", "SSBP1", "SSR4", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STT3A", "STT3B", "STUB1", "STX3", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCF20", "TCOF1", "TECR", "TELO2", "TERF2IP", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIMM22", "TIMM50", "TIMMDC1", "TKT", "TMCO1", "TMEM126A", "TMEM126B", "TMEM165", "TMEM199", "TMEM43", "TMEM70", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOP3A", "TOR1A", "TOR1AIP1", "TP53", "TPI1", "TPM1", "TPM3", "TPP1", "TPP2", "TRAPPC11", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSPYL1", "TTC19", "TTC37", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUFM", "TWNK", "TXNDC15", "UBA1", "UBAC2", "UBAP1", "UBE3A", "UBIAD1", "UBR7", "UBTF", "UFC1", "UFD1", "UFSP2", "UMPS", "UNC119", "UNC45A", "UPF3B", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP7", "USP9X", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", 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0000000000000000000000000000000000000000..33ef8af70bf03c8b67b30e4daa8b469c643a34fa --- /dev/null +++ b/msigdb_kegg/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4916de8670bf2d584d8d1a183776ffa6f6289bc852e99972820d703a566b2b30 +size 138963 diff --git a/msigdb_kegg/consensus.joblib b/msigdb_kegg/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..8c30e1092cc0d2c26c1d5c522a91a773fc47e5e7 --- /dev/null +++ b/msigdb_kegg/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:de71073dd0ddb2eb2230b312cc4a30a484e927fc81764852d75ca9046b69416d +size 79929 diff --git a/msigdb_kegg/df_merge.tsv b/msigdb_kegg/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3dfffb1ab23e54ab10e9e103e5dda71afdf4a06d --- /dev/null +++ b/msigdb_kegg/df_merge.tsv @@ -0,0 +1,11 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Lysosome 16 49 3.239353904492559 0.0011980082268605 21.740291262135923 48.609223300970875 0.8281821627988494 0.1302152537326229 7.142313942893836 4.247239237941681 3.086075071395461 0.2389623217115766 7.966459979336032e-13 7.178515274167897e-06 3.5805648422212265e-08 1.9469379794185524e-11 7.932644054525473e-09 +Snare interactions in vesicular transport 10 15 2.777328157875988 0.0054807812823316 5.803398058252427 13.6626213592233 0.8920027438628428 0.3386294703372389 3.103034547770364 2.9171839264116786 1.2201519782198902 0.3219991979242683 0.4568995785286112 1.0 1.0 0.0097601039903573 3.170481154810999e-05 +Cardiac muscle contraction 8 20 2.745095129457556 0.0060493359360001 7.728155339805825 19.856796116504853 1.0644813600437804 0.240240383706381 3.4195161605095614 1.765741250102918 1.6465694074711887 0.3002212677564749 0.1819837603944453 0.1952735388158895 0.0705821305211966 0.0044406378118471 0.0002580266226921 +Vibrio cholerae infection 3 20 2.486894456019196 0.0128863623204698 4.266990291262136 20.3495145631068 0.719353425420958 0.4383869162647907 2.394690257024947 1.7733668152523894 0.9402989147235556 0.3258958759345889 0.0044056772369422 0.0008441205885139 0.000529997208151 0.0142235096743441 0.0390278099301106 +Parkinsons disease 17 59 2.3394916635153424 0.0193100025207275 16.90776699029126 54.04126213592233 1.0315348591123816 0.3152611195514452 7.595108151251147 4.223805209268991 1.8494970521239744 0.3626807692210581 0.0019970766603954 9.028179583440972e-06 6.0829140550034186e-05 3.769325873542945e-05 1.9448488864003485e-06 +Sphingolipid metabolism 6 10 2.325581534378381 0.0200408856173712 5.672330097087379 11.759708737864075 0.9805985471070467 0.1821702203806468 2.452838935293596 1.3449033287601222 1.7625559835482287 0.2542774311591588 0.0008173905192854 1.0 0.2166826538338764 0.0028478177309091 0.000136356004925 +Calcium signaling pathway 5 15 2.2480463590989648 0.0245732339623279 5.735436893203883 16.946601941747574 1.0005800740695592 0.3113014190776675 2.984654368989517 2.3866666657890168 1.2450167285670062 0.3187454651207294 0.3095249089156006 0.0388410242837302 0.1312354716944213 0.4697159455465771 0.2072382474356869 +Riboflavin metabolism 2 5 2.146037528077944 0.0318699847271564 1.2597087378640777 5.470873786407767 0.8651682051380694 0.3242718261444057 1.1073575266667028 1.2430881579904736 0.9666566709677474 0.2578857718572043 0.0147099496631327 0.0516364610584135 0.1018169846714528 0.027832231049335 0.0140126286640228 +Oxidative phosphorylation 18 64 2.093175802794951 0.0363334639360071 18.79854368932039 59.0752427184466 1.0149760730411637 0.3252836463038503 7.263801581344288 4.652138947381941 1.8018345229041028 0.3643612228552857 0.0003962697406407 5.301792220889015e-07 6.611598485331693e-06 1.114101386375826e-06 1.6721459453788106e-08 +Steroid biosynthesis 6 13 1.961220351013914 0.0498533238502936 4.451456310679611 10.919902912621358 0.8535439655720318 0.1867209176898754 2.1463612955879627 1.3314318120676296 1.5430058140543457 0.1933818217769055 0.0015998581819158 1.0 0.1277572387780678 1.3414362359281e-05 1.5533184688236115e-06 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d686dda302d04745c811b36f79a1b4f84f0e0808 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 180, + "title": "Average number of proteins per term", + "value": 15.477777777777778 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..84cda1365c50d61a7e16fc1b96c7661638456d9f --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ae1db69207be1e9de9e48486ebe8d560028f9fd1 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,59 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Lysosome 0.6638576059151958 3.239353904492559 0.0011980082268605 0.1940799655400867 0.1668574927810895 49 O43681,Q14108,P50897,P16278,Q93050,P06865,Q8NHS3,Q9UMR5,P07602,O75503,P06280,Q8NCC3,P54802,O15118,P11117,Q9Y487 16 +Snare interactions in vesicular transport 0.7466759049103144 2.777328157875988 0.0054807812823316 0.6281460303693039 0.181480078080003 15 O43752,O95249,O15400,Q13277,Q9P2W9,O75396,O60499,Q9UNK0,Q12981,O14653 10 +Cardiac muscle contraction 0.6940129482994304 2.745095129457556 0.0060493359360001 0.6645181133813143 0.181480078080003 20 P22695,P16615,O14949,P14406,P00403,P20674,Q9UDW1,P13073 8 +Vibrio cholerae infection 0.6521448604927162 2.4868944560191957 0.0128863623204698 0.9031527336201504 0.2708764733850114 20 Q9Y487,Q93050,P24390 3 +Parkinsons disease 0.5525309461779058 2.3394916635153424 0.0193100025207275 0.9700970362311858 0.2708764733850114 59 O43676,P00846,O95182,P22695,O96000,O14949,P14406,O95168,P06576,P00403,P21796,P45880,P03886,P20674,Q9UDW1,Q9Y277,P13073 17 +Sphingolipid metabolism 0.7735817675468669 2.325581534378381 0.0200408856173712 0.9738523792417556 0.2708764733850114 10 O43681,P16278,O95470,Q13510,P06280,Q06136 6 +Calcium signaling pathway 0.6528067833377034 2.2480463590989648 0.0245732339623279 0.9886488372908038 0.2948788075479349 15 P16615,P21796,P45880,P20020,Q9Y277 5 +Riboflavin metabolism 0.8790759463728794 2.146037528077944 0.0318699847271564 0.997061922246329 0.327001175424064 5 Q9NPH0,P11117 2 +Oxidative phosphorylation 0.5241760396324436 2.093175802794951 0.0363334639360071 0.9987211486783628 0.327001175424064 64 O43676,P00846,O95182,P22695,O96000,O14949,Q93050,P14406,O95168,P06576,P00403,O75964,P03886,Q9Y487,Q9UDW1,P20674,Q7KZN9,P13073 18 +Steroid biosynthesis 0.6393210619052423 1.961220351013914 0.0498533238502936 0.9998994649228002 0.3710749885468645 13 Q14534,P37268,Q15392,Q15800,Q16850,O76062 6 +Porphyrin and chlorophyll metabolism 0.6539969077694878 1.940996018254819 0.0522587603380553 0.9999362969570942 0.3710749885468645 12 P22830,P30519,P09601 3 +Other glycan degradation 0.7322252308815894 1.9300574439242144 0.0535997205678804 0.9999506286761316 0.3710749885468645 8 Q9BTY2,P16278 2 +Protein export 0.574689075289109 1.8923418898576505 0.0584454430461798 0.9999804030659408 0.3755862760481513 16 P49458,Q9Y5M8,P67812,Q15070 4 +Abc transporters 0.6960340857549782 1.8519977584906195 0.0640261447835532 0.9999932784539576 0.3755862760481513 9 Q03518,O14678,P08183,P33527,O75027 5 +Glycosaminoglycan degradation 0.803965275201333 1.84041350410614 0.0657075523721391 0.9999951369259564 0.3755862760481513 5 P54802,P16278 2 +Nicotinate and nicotinamide metabolism 0.6923233777537046 1.5229435225622574 0.127772835824695 0.9999999999794256 0.5534960516868949 6 P49902,Q13423 2 +Glycosphingolipid biosynthesis ganglio series 0.7883426802170386 1.5122995083272937 0.1304576860852269 0.9999999999881878 0.5534960516868949 4 P06865,P16278 2 +Huntingtons disease 0.4544736820821427 1.465485097879461 0.1427886151867496 0.9999999999990968 0.5841352439457942 79 O43676,P00846,O96000,P22695,O95182,O14949,P14406,O95168,P06576,P09669,P00403,P21796,P45880,P20674,Q9UDW1,Q9Y277,P13073 17 +Metabolism of xenobiotics by cytochrome p450 0.5716303129948586 1.3190334514996396 0.1871579293798642 1.0 0.6708470325803771 10 P78417 1 +Glycerolipid metabolism 0.5175125320290326 1.2586064653613642 0.2081725106055363 1.0 0.6708470325803771 13 P06280,Q9HCL2,P51648,Q53H12,P30837 5 +Epithelial cell signaling in helicobacter pylori infection 0.4714946305913231 1.2468980178143698 0.2124348936504527 1.0 0.6708470325803771 18 Q9Y487 1 +N glycan biosynthesis 0.4577025154468834 1.2044073801010038 0.2284321609612241 1.0 0.6742882653399642 21 Q9BV10,Q9BT22,O60476,O60762,P46977,Q86YN1 6 +Alzheimers disease 0.4259614137707485 1.1840971755473024 0.2363745980686309 1.0 0.6742882653399642 60 O43676,P00846,O95182,P22695,P16615,O96000,O14949,P14406,O95168,P06576,P00403,P20674,Q9UDW1,P13073 14 +O glycan biosynthesis 0.8479436364471991 1.1565087233822382 0.2474731334994435 1.0 0.6742882653399642 3 O43505 1 +Renin angiotensin system 0.6940953572602435 1.1355640099993085 0.2561390784296224 1.0 0.6742882653399642 4 Q9UIQ6 1 +P53 signaling pathway 0.4964101252042504 1.1333617899493678 0.2570623532284992 1.0 0.6742882653399642 13 O14681,Q07812,P31350,P14635,Q13794 5 +Glycosphingolipid biosynthesis globo series 0.8392143995673305 1.124952781849353 0.2606090436518165 1.0 0.6742882653399642 3 P06280 1 +Glycerophospholipid metabolism 0.4531249159229543 1.121105723092515 0.2622428628729598 1.0 0.6742882653399642 18 Q9HCL2 1 +Cell adhesion molecules cams 0.5179435324784109 1.104959879465914 0.2691769741083392 1.0 0.6742882653399642 11 Q16625,Q92896 2 +Progesterone mediated oocyte maturation 0.4191874306231478 0.96553127112726 0.334278780937616 1.0 0.7611487406389785 23 P04899,Q9UJX3,P31751 3 +Biosynthesis of unsaturated fatty acids 0.4680447613608224 0.9000691017584985 0.3680834779196815 1.0 0.788750309827889 12 O15254 1 +Gap junction 0.4477884608870524 0.785156067505228 0.4323620700083928 1.0 0.8696705381014829 12 P07437,P04899,Q9BVA1 3 +Antigen processing and presentation 0.3917139125189161 0.6955366242167897 0.4867190674422901 1.0 0.8696705381014829 17 Q03518,Q9UL46,P04439,P10321 4 +Galactose metabolism 0.424330702149994 0.6537833406864351 0.5132514009286486 1.0 0.8696705381014829 12 P16278 1 +Graft versus host disease 0.7026745515859893 0.6507802768883156 0.5151883337189656 1.0 0.8696705381014829 3 P10321 1 +Autoimmune thyroid disease 0.7026745515859893 0.6507802768883156 0.5151883337189656 1.0 0.8696705381014829 3 P10321 1 +Allograft rejection 0.7026745515859893 0.6507802768883156 0.5151883337189656 1.0 0.8696705381014829 3 P10321 1 +Proteasome 0.3405410956578905 0.5855251184698252 0.5581946820464063 1.0 0.8696705381014829 34 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Steroid hormone biosynthesis 0.5490918364764727 0.5774971189699443 0.5636036842922842 1.0 0.8696705381014829 4 Q53GQ0 1 +Mismatch repair 0.3653989165726485 0.5231284547232051 0.600884865193478 1.0 0.8696705381014829 17 Q9UQ84,P41440 2 +Retinol metabolism 0.4873901304854945 0.5182320425404278 0.6042963809226489 1.0 0.8696705381014829 5 Q6NUM9,Q9BTZ2 2 +Inositol phosphate metabolism 0.4332642999098585 0.5099359270978319 0.6100963509629642 1.0 0.8696705381014829 8 Q10713,Q9UNW1 2 +Dilated cardiomyopathy 0.423120919494039 0.5030403241785426 0.6149359216417531 1.0 0.8696705381014829 9 P16615,P50402,P67936 3 +Phosphatidylinositol signaling system 0.4302273745452204 0.4963675910331434 0.6196350863707516 1.0 0.8696705381014829 8 Q10713 1 +Type i diabetes mellitus 0.4726301980556598 0.326762137474121 0.7438477986655507 1.0 0.9350449535414465 4 P10321 1 +Endometrial cancer 0.3824068640838989 0.3212301799194182 0.7480359628331572 1.0 0.9350449535414465 9 P35222,Q13418,P35221,P31751 4 +Rna degradation 0.3062067844751194 0.2936283183714813 0.7690419342368644 1.0 0.9377166462632904 34 Q9Y4Y9,Q5RKV6,O95453,Q6PGP7,Q9UK45,Q9NQT5,Q96B26,P62310,Q13868 9 +Apoptosis 0.3273175114591402 0.2880287871862087 0.7733247029891226 1.0 0.9377166462632904 17 O95831,P31751 2 +Glycosaminoglycan biosynthesis heparan sulfate 0.5481229258187911 0.2295150050342397 0.8184686595374984 1.0 0.9692392020838796 3 O94923 1 +Cytosolic dna sensing pathway 0.3664294954721794 0.1717207489196902 0.8636570728421606 1.0 1.0 6 Q9NZI8,Q7Z434,O14802,O15160,P55265 5 +Nucleotide excision repair 0.3040022264758231 0.15061639123957 0.8802783305637509 1.0 1.0 21 P41440,P41208 2 +Hypertrophic cardiomyopathy hcm 0.3259662698737688 0.1372932646450091 0.8907989940590817 1.0 1.0 11 P16615 1 +Rig i like receptor signaling pathway 0.3663110248949207 0.1372544250922508 0.8908296929252546 1.0 1.0 5 Q14258,Q7Z434,Q13526,O00571 4 +Primary bile acid biosynthesis 0.4673772609819247 0.111328271660364 0.911356037206484 1.0 1.0 2 P22307 1 +Melanogenesis 0.3248863713119913 0.0940189431413647 0.9250941089390684 1.0 1.0 8 P63096,P04899,Q13555 3 +Folate biosynthesis 0.4513731825524845 0.0830370159143579 0.9338221067901362 1.0 1.0 3 P35270,P00374 2 +Olfactory transduction 0.4331395348837176 0.0821418719713797 0.9345338965890342 1.0 1.0 2 Q13555 1 +Basal cell carcinoma 0.3641357027463643 0.0291022749586082 0.9767830214131612 1.0 1.0 3 P35222,Q9UJX6 2 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5f2d2ab5f2416c0427b0e8677dbfcbd7ff81ff8e --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTN1", "ACTN4", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGA", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALYREF", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEX1", "APRT", "AQR", "ARF6", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AURKA", "B3GAT3", "B4GAT1", "BAIAP2", "BAX", "BCAS2", "BCAT2", "BCKDHA", "BCKDHB", "BIRC6", "BLM", "BLVRA", "BNIP1", "BRCA1", "BUB1B", "BUB3", "BUD23", "BUD31", "CAB39", "CACYBP", "CAD", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CAPN2", "CARS", "CARS2", "CASK", "CBR1", "CCDC6", "CCNB1", "CD47", "CDC16", "CDC23", "CDC27", "CDC34", "CDC40", "CDC42", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDKN2A", "CETN2", "CFL1", "CFL2", "CHD8", "CHDH", "CHEK1", "CHERP", "CHMP2A", "CHMP6", "CHORDC1", "CHP1", "CHST14", "CKB", "CKMT1A*", "CLN5", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT9", "COMT", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPOX", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CS", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CXADR", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DBT", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DECR2", "DERL1", "DFFA", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIS3", "DLAT", "DLD", "DLST", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DOLPP1", "DPM1", "DPYSL2", "DPYSL5", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENDOD1", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPRS", "EPS15", "ERBIN", "ERCC3", "ERO1A", "EXO1", "EXOC3", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAR1", "FAR2", "FARS2", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GCAT", "GCDH", "GCLC", "GGCT", "GGH", "GLA", "GLB1", "GLCE", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPI", "GPT2", "GRB2", "GRHPR", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HDAC1", "HDAC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HK1", "HK2", "HLA-A", "HLA-C", "HMGB1", "HMGCL", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGF2BP1", "IGF2R", "ILK", "IMPDH2", "IQGAP1", "IQGAP2", "IRS4", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "JUP", "KARS", "KDELR1", "KDELR3", "KDSR", "KEAP1", "KIDINS220", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAP3", "LARS", "LARS2", "LCLAT1", "LDHA", "LDHB", "LDLR", "LGMN", "LIG1", "LIG3", "LIPA", "LMNA", "LMO7", "LNPEP", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LYN", "LYPLA1", "M6PR", "MAN1A2", "MAN2A1", "MAN2B1", "MAPK1", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MFSD8", "MGAT1", "MGST1", "MGST2", "MGST3", "MID1", "MIF", "MINPP1", "MMAB", "MOGS", "MPG", "MPHOSPH6", "MPI", "MPST", "MRE11", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTR", "MUT", "MYH10", "MYH9", "MYL6", "MYL6B", "NAE1", "NAGLU", "NAMPT", "NANS", "NARS", "NBN", "NCAM1", "NCBP1", "NCBP2", "NCKAP1", "NCL", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NLN", "NME1", "NME6", "NNT", "NPC1", "NPC2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NT5C2", "NT5C3A", "NTHL1", "NUDT12", "NUDT19", "NUDT5", "NUDT9", "OAT", "OCLN", "OGDH", "ORC2", "ORC3", "ORC6", "OXA1L", "OXCT1", "P4HA1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PC", "PCBP1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDCD6IP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PECR", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGS1", "PHF5A", "PHGDH", "PI4KA", "PIAS1", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PLA2G15", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLXNB2", "PMAIP1", "PMPCA", "PMVK", "PNP", "PNPLA4", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "PPA1", "PPA2", "PPAT", "PPID", "PPIE", "PPIH", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKDC", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRSS3", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PTDSS1", "PTDSS2", "PTGES2", "PTPN1", "PUF60", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "RAB11B", "RAB11FIP1", "RAB13", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAC1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RALA", "RAPGEF2", "RARS", "RARS2", "RBM17", "RBM22", "RBM25", "RBM8A", "RBMX", "RBPJ", "RCOR1", "RDH11", "RDX", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RIPK1", "RNASEH2A", "RPA1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RSL24D1", "RUVBL1", "SAE1", "SARS", "SARS2", "SART1", "SC5D", "SCARB2", "SCD", "SCP2", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SETD2", "SETDB1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SGPL1", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A1", "SLC33A1", "SLIT2", "SLK", "SLTM", "SMC1A", "SMC3", "SMNDC1", "SMPD4", "SNAP23", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORD", "SPCS2", "SPCS3", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "STAG1", "STAG2", "STAT1", "STAT3", "STIP1", "STMN1", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SYMPK", "TAB1", "TAF6L", "TAF9B", "TALDO1", "TAP1", "TAP2", "TARS", "TARS2", "TBL1XR1", "TCERG1", "TECR", "TFAM", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "TJP1", "TK1", "TKT", "TLN1", "TM7SF2", "TOMM40", "TOP3A", "TP53", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TRA2A", "TRA2B", "TRIM25", "TRIP12", "TROVE2", "TSG101", "TTC37", "TUBB", "TUBB2B", "TUBB6", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBR5", "UMPS", "UNC45A", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USP39", "VAMP7", 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0.3154426595544552 0.705668001925547 1.0 0.4960773916621825 0.5088214927290686 0.2522352051807391 +Cholesterol biosynthesis 7 17 1.995060408026184 0.0460362918112104 5.878640776699029 16.75 1.3996798653689082 0.2350718901934974 2.503362805703168 1.8986773628384943 1.0886216368414 0.270950573691616 0.0006959080837836 1.0 0.208984012191681 1.774557205833731e-05 1.0761884384293304e-05 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..301f7d07c57a09f1ef71e694be8d7f7b35c20511 --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 1367, + "title": "Average number of proteins per term", + "value": 18.910753474762252 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1738fb557488223786744fdcbd18271efab5117f --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b18049520e985183f6b30c30f35b5262c41574d1 --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,356 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transport of small molecules 0.4908966369114718 4.063330111912255 4.8377535961652285e-05 0.0639942799559029 0.06613209165958 163 P30519,P16615,P02786,Q4KMQ2,P21796,P45880,Q70HW3,O00400,P20618,P04114,Q9Y487,P27105,P33527,Q9C0H2,O75027,P51790,Q8WTV0,Q93050,Q92667,Q15758,Q9UJZ1,P51665,P28070,O15118,Q8TB61,Q9UBX3,P53985,P61916,P28072,P98194,Q6PIU2,Q9UL46,P09601,Q9HD20,P49721,Q96PU5,P08183,Q92530,P20020,Q9Y5K8,Q9Y277,Q9Y6M7,Q9UBV2,P30825,P28074,O00231,O95202,P63218,Q96TA2,Q10713,Q8TDW0,Q9UEY8 52 +Mitochondrial protein import 0.6816349847810377 3.389547349039379 0.000700081175385 0.6160896110982792 0.2742433021400558 36 Q8N4H5,Q99595,O60830,Q9NS69,P21796,Q13505,Q15388,O75746,Q9Y584,Q10713,O75431,P62072,Q9UJS0 13 +Ion channel transport 0.6006449785821604 2.805410516173631 0.0050252532528864 0.9989788642422018 0.2742433021400558 32 P16615,P51790,Q93050,P98194,Q4KMQ2,Q9HD20,P35670,Q96PU5,P20020,Q9Y487,Q9Y5K8,Q9C0H2,P27105 13 +Mitochondrial calcium ion transport 0.7261722920026876 2.798808763761968 0.0051291504875556 0.9991147071690832 0.2742433021400558 16 O95202,Q9UJZ1,P21796,P45880,Q96TA2,Q10713,Q9Y277 7 +Intra golgi traffic 0.6813701941206383 2.540658669536713 0.0110643877063891 0.9999997518704624 0.2965689802869413 16 O43752,O95249,Q9UP83,Q9Y2V7,O00461,Q9NRW7,P83436,O60476,Q13190,O14653 10 +Cristae formation 0.6462915699822767 2.487310482064525 0.01287130119117 0.99999997963169 0.3136363858870818 21 O75964,P00846,Q5XKP0,Q13505 4 +Protein localization 0.5574952896768782 2.450159783905147 0.0142792833313432 0.9999999971055932 0.3308437341346807 78 O43681,P46379,O15254,Q99595,O60830,P21796,Q9Y584,O14734,Q9UJS0,Q9NS69,Q15388,P62072,Q13505,Q8N4H5,O75381,P09601,P50402,P35914,P51648,O75746,O75431,Q13011,Q9NR77,Q10713 24 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.8081175723112222 2.373752503452743 0.0176083488543514 0.999999999971612 0.363794056311205 9 O43681,P09601,P46379,P51648 4 +Sphingolipid metabolism 0.5917676551083307 2.343822005674462 0.0190872780114643 0.99999999999638 0.3715183081010593 26 O43681,P16278,P06865,O95470,P07602,Q13510,P06280,P10619,Q06136,Q9NZJ7,P51648,O15269,Q96G23 13 +Synthesis of pa 0.7812364049363298 2.251502853999312 0.0243537063328838 0.9999999999999976 0.4165499497656384 9 Q9NPH0 1 +Metabolism of porphyrins 0.7731398157055636 2.2143242119715136 0.0268064842274236 1.0 0.4165499497656384 9 P30519,P22830,P09601,P50336,Q7KZN9 5 +Pink1 prkn mediated mitophagy 0.7951610215920497 2.213886760490119 0.0268365697153369 1.0 0.4165499497656384 8 P21796,Q8N4H5,Q9NS69 3 +Iron uptake and transport 0.6097521214628709 2.1581769243877407 0.0309140787814683 1.0 0.431219854023135 18 Q93050,Q9Y487,P30519 3 +Formation of atp by chemiosmotic coupling 0.7100327311665755 2.121141572060114 0.0339098904176971 1.0 0.4544590215783522 11 P00846 1 +Glycosaminoglycan metabolism 0.6289168267655725 2.1078793481578253 0.0350414270137737 1.0 0.4650643759983373 15 P16278,P06865,P54802,P15586,Q8NCH0,Q8TB61,O43505,O94923 8 +Recruitment of numa to mitotic centrosomes 0.5348599754679993 2.0887456145843504 0.0367306283793671 1.0 0.4827958557172583 29 O94927,P07437,Q9BUF5,O75935,P41208,Q9BVA1,Q9H6D7 7 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.7370144815714393 2.046421791879686 0.0407148898534464 1.0 0.5201612563519741 9 O43681,P38435,Q9BU89,P49366,O60725,Q8NBJ7 6 +Glycosphingolipid metabolism 0.6160555075160258 2.031488969200829 0.0422054173993742 1.0 0.5266060855073211 15 O43681,P16278,P06865,P07602,P06280 5 +Stimuli sensing channels 0.7115792503834054 2.0277137371866387 0.0425894727919944 1.0 0.5266060855073211 10 P27105,Q96PU5,P51790,Q9C0H2 4 +Cell surface interactions at the vascular wall 0.591861946484691 2.020953664284937 0.0432845618882546 1.0 0.5283035366182515 17 P53985,P14174,P04114,Q92896 4 +Cholesterol biosynthesis 0.5877610077409692 1.995060408026184 0.0460362918112104 1.0 0.5464000807377946 17 Q9BWD1,Q14534,P37268,Q15392,Q15800,Q16850,O76062 7 +Transport of inorganic cations anions and amino acids oligopeptides 0.692089350381054 1.931924841806956 0.053368783120989 1.0 0.6092040387159152 10 Q9Y6M7,Q70HW3,P30825,Q9UBX3 4 +Mitophagy 0.6498533220457035 1.9187221322780503 0.0550195090002767 1.0 0.6201955480977529 12 P21796,Q9NS69 2 +Pre notch processing in golgi 0.8911346977111809 1.9161162713227904 0.0553502976356443 1.0 0.6201955480977529 4 Q9UBV2,P16615 2 +Metabolism of fat soluble vitamins 0.7733375797168105 1.8753339398315372 0.0607467969563215 1.0 0.6651591574502221 6 Q8N0U8,Q9Y5Z9,P04114 3 +Recruitment of mitotic centrosome proteins and complexes 0.5256416108276767 1.8637748315246012 0.0623533315973365 1.0 0.6697177259520738 26 O94927,O75935,Q9H6D7,P41208 4 +Heme degradation 0.8726183609046263 1.8442740746783788 0.0651432077578235 1.0 0.6697177259520738 4 P30519 1 +Phase i functionalization of compounds 0.5848553044960326 1.843496603076799 0.0652565372294438 1.0 0.6697177259520738 15 O43169,P07099,P30837,Q16850 4 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.4948758075571063 1.8294064150986429 0.067338747308852 1.0 0.6697177259520738 68 P00846,O95182,P00403,Q9NPL8,P03886,O75880,O43676,O14949,O75964,P13073,P22695,O95168,O75380,P20674,Q9UDW1,Q86Y39,O96000,P06576,P09669,O43819,Q9Y375,Q9P0J0,Q8TB37 23 +Anchoring of the basal body to the plasma membrane 0.5204512507146368 1.8250700843141168 0.0679904539327642 1.0 0.6697177259520738 26 O94927,O75935,Q9H6D7,P41208 4 +Unwinding of dna 0.7065267335381147 1.8115338434358208 0.0700582551654327 1.0 0.6697177259520738 8 Q9BRX5,P33991 2 +Binding and uptake of ligands by scavenger receptors 0.6856698319571192 1.8021757637286515 0.0715177565798055 1.0 0.6789220364207927 9 Q8WTV0 1 +Beta oxidation of pristanoyl coa 0.8511211932749541 1.7603268945622343 0.0783523966540631 1.0 0.6961662062331602 4 O15254 1 +Sphingolipid de novo biosynthesis 0.6375692917117168 1.7484622169030222 0.0803840225949901 1.0 0.6961662062331602 11 Q96G23,O95470,P51648,Q06136 4 +Signaling by insulin receptor 0.5688593244838007 1.7456786243480231 0.0808668114674286 1.0 0.6961662062331602 15 Q93050,Q9Y487 2 +Ion transport by p type atpases 0.5994968731600908 1.736319502977974 0.0825073566347287 1.0 0.6961662062331602 13 Q04656,P16615,P98194,Q9HD20,P35670,P20020,P23634 7 +Mrna decay by 3 to 5 exoribonuclease 0.5656769788509892 1.7261055251110755 0.0843284300308662 1.0 0.6961662062331602 15 Q5RKV6,Q6PGP7,Q9NQT5,Q96B26,Q969T7,Q13868 6 +Slc mediated transmembrane transport 0.5094653574774239 1.7014884762661602 0.0888512999142117 1.0 0.6961662062331602 25 Q9Y6M7,P30825,Q9H936,Q15758,P36404,P35613,Q70HW3,O00400,Q8TB61,Q9UBX3,P53985 11 +Hs gag degradation 0.9635012919896624 1.683444720431939 0.0922890321964011 1.0 0.6961662062331602 2 P16278 1 +Synaptic adhesion like molecules 0.8293089471090039 1.6745989638021703 0.0940129427230718 1.0 0.6961662062331602 4 O95197,P41440 2 +Abacavir transport and metabolism 0.960271317829456 1.67060137848537 0.0948004400411397 1.0 0.6961662062331602 2 P08183 1 +Ire1alpha activates chaperones 0.5050967336966672 1.669036439930512 0.0951101583103293 1.0 0.6961662062331602 25 P43307,Q9Y5M8,O43731,O14653,O14773,Q9NWM8 6 +Aurka activation by tpx2 0.4996685130805205 1.668661548226709 0.0951844736487674 1.0 0.6961662062331602 26 O94927,O75935,Q9H6D7,P41208 4 +Keratan sulfate keratin metabolism 0.7555558468536002 1.638718470202907 0.1012719055633089 1.0 0.7003899740798579 5 P06865,O43505,P16278 3 +Striated muscle contraction 0.7153155969942748 1.6240398771467857 0.1043672981264993 1.0 0.7048909890871915 6 P08670,P28289,P67936 3 +Complex i biogenesis 0.4554022676154417 1.61372871084845 0.106586283524225 1.0 0.7048909890871915 33 O43676,O96000,O95182,O95168,Q9NPL8,Q8TB37,P03886,Q9Y375,Q9P0J0,O75380,Q86Y39 11 +Initiation of nuclear envelope ne reformation 0.5282023796827275 1.6110593244283309 0.1071667928163233 1.0 0.7048909890871915 17 Q86XL3,P42167,P50402,P14635 4 +Signal amplification 0.7473941766231242 1.6043938822141683 0.1086272586743741 1.0 0.7071117267041404 5 P63218,Q14344,P04899 3 +Ros and rns production in phagocytes 0.6438753882435334 1.5987436142809262 0.1098775823613278 1.0 0.7099863882867562 9 Q9Y487 1 +Downregulation of erbb2 signaling 0.7093100968804189 1.5977096129836523 0.1101076183736593 1.0 0.7099863882867562 6 P31751 1 +Heparan sulfate heparin hs gag metabolism 0.7418391466611678 1.5809842140746877 0.113881647199745 1.0 0.7218968859218041 5 P54802,P16278,O94923 3 +Deadenylation dependent mrna decay 0.4535443434007892 1.5801736639763484 0.1140671012136866 1.0 0.7218968859218041 35 Q9Y4Y9,Q5RKV6,O95453,Q6PGP7,Q9UK45,Q9NQT5,Q969T7,Q96B26,P62310,Q13868,Q9HBH5 11 +Copi mediated anterograde transport 0.4627913656356042 1.5736197812976778 0.1155753772796095 1.0 0.7225960681053865 48 Q15363,Q9UJW0,O95249,Q9UP83,P24390,Q9BVK6,Q9BUF5,O75935,Q13561,Q9Y3B3,Q9BVA1,O43731,O14653 13 +Rac2 gtpase cycle 0.4487933394827506 1.5563536827552706 0.1196240126124799 1.0 0.7336069831154635 33 O15173,P42166,P42167,P49257,P02786,Q6IAA8,Q96RT1,P50402,Q86XL3,Q86Y07,Q13505 11 +Plasma lipoprotein clearance 0.5375019606449724 1.551262127798498 0.1208388788136036 1.0 0.7374408363312331 15 Q6PIU2,O15118,P04114,Q8WTV0 4 +Respiratory electron transport 0.4587544674919264 1.5011461710812664 0.1333177590335834 1.0 0.7828225445713748 57 O95182,P00403,Q9NPL8,P03886,O75880,O43676,O14949,P13073,P22695,O95168,O75380,P20674,Q9UDW1,Q86Y39,O96000,P09669,O43819,Q9Y375,Q9P0J0,Q8TB37 20 +Insulin receptor recycling 0.6066829631672843 1.5006837754256837 0.1334373714559418 1.0 0.7828225445713748 10 Q9Y487 1 +Bmal1 clock npas2 activates circadian gene expression 0.7850736047944041 1.49928693333164 0.1337992107007166 1.0 0.7828225445713748 4 P43490 1 +Plasma lipoprotein assembly remodeling and clearance 0.5044557994970674 1.489816568175363 0.1362724735128162 1.0 0.7828225445713748 19 Q6PIU2,O15118,P04114,Q8WTV0 4 +Golgi associated vesicle biogenesis 0.476068109976153 1.4884260014514723 0.1366385836842918 1.0 0.7828225445713748 26 Q9H3P7,P50570,O14976,Q9Y5X1,Q8NC96,O00203,O75976,O60749 8 +Intra golgi and retrograde golgi to er traffic 0.4535243807950558 1.4832673718347376 0.1380033875967938 1.0 0.7828225445713748 85 O43752,Q07866,Q9UJW0,P52732,Q6NUQ1,Q9NRW7,O00461,Q8N2H4,Q12981,Q15363,P24390,Q9UP83,Q9BVA1,O43731,Q15102,O60476,Q9Y3B3,O14653,O95249,Q9BVK6,Q9BUF5,O75935,Q9P2W9,Q13561,P83436,O60499,P40616 27 +Metabolism of lipids 0.3439645660388063 1.4726319069030307 0.1408503164722452 1.0 0.7828225445713748 202 Q9H7Z7,O43681,Q9BWD1,O15254,Q9NPH0,Q9UMR5,Q9HCL2,P07602,Q9BZK7,Q71SY5,Q9BZF3,O14734,Q96G23,Q53GQ0,P50897,P06865,P37268,Q15392,Q13510,Q9Y6K0,Q8NCC3,Q16850,Q53H12,Q99943,O43772,P16278,P35914,Q15800,P51648,O76062,Q14534,P50416,Q15165,P38435,P06280,P23786,Q10713,Q06136,Q8IY17 39 +Selective autophagy 0.4656017724267025 1.447423499531485 0.147778348039429 1.0 0.7901019700313768 27 Q8N4H5,Q9NS69,P21796,P08670,Q9BVA1,Q15388 6 +Diseases associated with n glycosylation of proteins 0.6125175218540581 1.4436905594811411 0.148826038162062 1.0 0.7901019700313768 9 Q9BV10,Q9H553,Q9BT22 3 +Er quality control compartment erqc 0.770246833661594 1.4401783031118585 0.1498169600404661 1.0 0.7901019700313768 4 Q8WU17 1 +Rhod gtpase cycle 0.4625099493289972 1.4230857826035577 0.1547112893008895 1.0 0.7920986234993108 27 P42166,O15173,P42167,Q9Y6M7,Q9BX68,P50402,P20700,Q9UEY8,Q86Y07 9 +Mitochondrial biogenesis 0.4363642443235198 1.4207525658899034 0.1553887049002162 1.0 0.7925983567111778 36 P00846,O75964,Q9BZK7,Q5XKP0,O75431,Q13505 6 +Transferrin endocytosis and recycling 0.5738936901539593 1.4093525040194657 0.158730960871499 1.0 0.8066365186295138 11 Q9Y487 1 +Scavenging by class a receptors 0.7004138307388901 1.405356184277824 0.1599153889784557 1.0 0.8089105689018337 5 Q5KU26 1 +Assembly and cell surface presentation of nmda receptors 0.6944938512903197 1.3801313403181066 0.1675462092608108 1.0 0.830151448350883 5 P07196,Q9BVA1 2 +Rhof gtpase cycle 0.4933323273523805 1.379957550227732 0.1675997153522892 1.0 0.830151448350883 17 Q9Y6M7,Q9UEY8,P42167,P20700 4 +Sialic acid metabolism 0.7551650743756407 1.379926692572678 0.1676092170774277 1.0 0.830151448350883 4 Q9NR45,P16278 2 +Keratan sulfate degradation 0.7485664238645767 1.35353488299729 0.1758848138077247 1.0 0.8350740281540109 4 P16278 1 +The citric acid tca cycle and respiratory electron transport 0.4278299783688351 1.3482048925316124 0.1775924914546831 1.0 0.8350740281540109 102 P00846,O95182,P00403,Q9NPL8,P21796,P03886,O75880,O43676,O14949,O75964,P53985,Q13423,P13073,P22695,O95168,O95563,O75380,P20674,Q9UDW1,Q86Y39,O96000,P06576,P09669,O43819,Q9Y375,Q9P0J0,Q8TB37 27 +Protein protein interactions at synapses 0.5767165023908177 1.3455220102422345 0.1784567183026455 1.0 0.8350740281540109 10 O95197,P41440 2 +Cytoprotection by hmox1 0.4427892733314704 1.3346457998146806 0.181992300595706 1.0 0.8350740281540109 65 P30519,P00403,Q9BZK7,P20618,O75880,P33527,P51665,P28070,Q14145,P13073,P28072,P09601,P49721,Q92530,P20674,O00231,P28074,P09669,O43819 19 +Gaba receptor activation 0.7424633579997135 1.329113329209341 0.1838105833735039 1.0 0.8350740281540109 4 P63218,P04899 2 +Gaba b receptor activation 0.7424633579997135 1.329113329209341 0.1838105833735039 1.0 0.8350740281540109 4 P63218,P04899 2 +Adp signalling through p2y purinoceptor 12 0.7424633579997135 1.329113329209341 0.1838105833735039 1.0 0.8350740281540109 4 P63218,P04899 2 +G alpha z signalling events 0.6484927751001406 1.3283359036887803 0.1840671637462141 1.0 0.8350740281540109 6 P63218,P04899 2 +O linked glycosylation 0.7408891878065264 1.3228127858729652 0.1858976441726125 1.0 0.8350740281540109 4 O43505,Q86SF2 2 +Platelet calcium homeostasis 0.6799255428325529 1.3179600563656817 0.187517019635079 1.0 0.8350740281540109 5 Q13586,P20020,P16615 3 +Scavenging by class b receptors 0.8691860465116139 1.3078733964827094 0.1909162542646634 1.0 0.8418790954186931 2 Q8WTV0 1 +Methylation 0.6424039907365181 1.3011502626091702 0.1932070261035807 1.0 0.8435571406050654 6 P78417 1 +Ra biosynthesis pathway 0.7350797927945688 1.299557096362243 0.1937528124214458 1.0 0.8435571406050654 4 Q9BTZ2,Q9HBH5 2 +Diseases of carbohydrate metabolism 0.5824657543633374 1.2935065354845243 0.1958359251643915 1.0 0.8435571406050654 9 P54802,P15586,Q7Z4W1,P16278 4 +Apc c cdc20 mediated degradation of cyclin b 0.5511626925214814 1.286188997008865 0.1983771101339795 1.0 0.8435571406050654 11 Q9UJX6,Q96DE5,P14635,P30260,P06493,Q16763,Q9UJX3 7 +Rhog gtpase cycle 0.419913658886536 1.2837987535683024 0.1992123798369993 1.0 0.8435571406050654 35 O15173,P42166,P42167,P02786,Q6IAA8,Q96RT1,Q16718,O95202,P50402,Q86XL3,Q13190,Q86Y07 12 +Phosphorylation of the apc c 0.5345408787346374 1.2793469242217583 0.200774915314513 1.0 0.8435571406050654 12 Q9UJX6,Q96DE5,P14635,P30260,P06493,Q16763,Q9UJX3 7 +Diseases associated with glycosaminoglycan metabolism 0.7272435613572792 1.2681821148108885 0.2047329225280716 1.0 0.8435571406050654 4 Q8NCH0 1 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.6303826197476612 1.2474018948324397 0.2122501721342768 1.0 0.8435571406050654 6 Q16850 1 +Depolymerisation of the nuclear lamina 0.5433590229622176 1.2437197520537868 0.213602723806459 1.0 0.8435571406050654 11 P14635,P42167,P50402 3 +Rhoa gtpase cycle 0.4218126989809289 1.2418967944047916 0.2142746429852782 1.0 0.8435571406050654 42 O15173,P30519,Q96HY6,P42167,Q96RT1,O75955,Q9P0I2,P51572,Q9Y4F1,P27105,P41440 11 +Synthesis of leukotrienes lt and eoxins ex 0.8494832041343683 1.22979931320464 0.2187722654791024 1.0 0.8487132105347013 2 P33527 1 +Rac3 gtpase cycle 0.416442854921159 1.227790790878519 0.2195255135844211 1.0 0.8487132105347013 31 O15173,P42166,P42167,P49257,P02786,Q6IAA8,Q96RT1,Q15758,P50402,Q9UQB8,Q86Y07 11 +Transport of connexons to the plasma membrane 0.8433462532299749 1.2055585913513482 0.2279877336098557 1.0 0.8487132105347013 2 Q9BVA1 1 +Gap junction assembly 0.8433462532299749 1.2055585913513482 0.2279877336098557 1.0 0.8487132105347013 2 Q9BVA1 1 +Copi dependent golgi to er retrograde traffic 0.417122722800293 1.199419798044428 0.2303647531502941 1.0 0.8487132105347013 42 Q15363,Q07866,P24390,Q9BVK6,P52732,Q6NUQ1,Q9BUF5,Q9P2W9,Q9Y3B3,Q9BVA1,O43731,Q12981 12 +Rora activates gene expression 0.7090855514019756 1.1954951522418291 0.2318936291569073 1.0 0.8487132105347013 4 Q9BZK7 1 +Heme biosynthesis 0.6499764382300117 1.189896543828742 0.2340870570660587 1.0 0.8487132105347013 5 P22830,Q7KZN9 2 +Ripk1 mediated regulated necrosis 0.5328410718825711 1.186362493206969 0.2354791769520527 1.0 0.8487132105347013 11 O75955,P41440 2 +Unfolded protein response upr 0.4148157142216818 1.1863611524964 0.2354797061891274 1.0 0.8487132105347013 41 P43307,O95070,Q5RKV6,O95453,Q9Y3B2,Q9Y5M8,P35611,Q13868,Q9NQT5,Q96B26,O43731,O14653,O14773,Q9NWM8 14 +Glycerophospholipid biosynthesis 0.4067094710183019 1.175642892282693 0.2397376079625395 1.0 0.8487132105347013 34 Q9NPH0,Q9Y6K0,Q9HCL2,Q8NCC3,Q53H12 5 +Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.4608333355488943 1.1739580129943672 0.2404118437223859 1.0 0.8487132105347013 18 Q9BV10,Q9BT22,P16278,Q9NR45,O60762,Q86YN1 6 +Mucopolysaccharidoses 0.8492151319351526 1.1611109482186617 0.2455967829769583 1.0 0.8487132105347013 3 P16278 1 +Transport of bile salts and organic acids metal ions and amine compounds 0.7002396880374442 1.160116368871595 0.2460014305549394 1.0 0.8487132105347013 4 P35613,P53985 2 +O linked glycosylation of mucins 0.8479436364471991 1.1565087233822382 0.2474731334994435 1.0 0.8487132105347013 3 O43505 1 +Arachidonic acid metabolism 0.5933673096982315 1.1486298555862178 0.2507086407812564 1.0 0.8487132105347013 7 Q9H7Z7 1 +Regulation of plk1 activity at g2 m transition 0.4129092124793401 1.1484654688255629 0.2507764602789102 1.0 0.8487132105347013 30 O94927,O75935,P41208,P14635,Q9H6D7 5 +Hs gag biosynthesis 0.8217054263565926 1.1204685030804176 0.2625141673601474 1.0 0.8487132105347013 2 O94923 1 +Thromboxane signalling through tp receptor 0.8191214470284245 1.1103561785474902 0.2668455736749422 1.0 0.8487132105347013 2 P63218 1 +The activation of arylsulfatases 0.8181524547803455 1.1065670186211776 0.2684811734395578 1.0 0.8487132105347013 2 O43681 1 +G alpha s signalling events 0.6299104525909671 1.104105051935995 0.2695475700634491 1.0 0.8487132105347013 5 P63218,P04899 2 +Signaling by erbb2 0.5154861493187763 1.0915210920832317 0.2750436560829692 1.0 0.8487132105347013 11 P31751 1 +Ion homeostasis 0.4925120628676276 1.0396968856600852 0.2984807479654292 1.0 0.8487132105347013 12 P16615,P05023,P20020,Q13586,P23634 5 +Cardiac conduction 0.4925120628676276 1.0396968856600852 0.2984807479654292 1.0 0.8487132105347013 12 P16615,P05023,P20020,Q13586,P23634 5 +Amino acid transport across the plasma membrane 0.8135915966286227 1.032821210947002 0.301687575572336 1.0 0.8487132105347013 3 P30825 1 +Proton coupled monocarboxylate transport 0.7987726098191046 1.031161202962554 0.302465230914001 1.0 0.8487132105347013 2 P53985 1 +Atf4 activates genes in response to endoplasmic reticulum stress 0.4902022542535568 1.026500363317136 0.3046557924573707 1.0 0.8487132105347013 12 Q5RKV6,O95453,Q9NQT5,Q96B26,Q13868,Q9Y3B2 6 +Phospholipid metabolism 0.4041379323922232 1.0248751469079025 0.3054221027951507 1.0 0.8487132105347013 50 Q9NPH0,Q9Y6K0,Q9HCL2,Q8NCC3,Q10713,Q53H12,Q99943,Q8IY17 8 +Processing of smdt1 0.5024682646796375 1.0203178824318937 0.3075777250234353 1.0 0.8487132105347013 11 Q10713,Q96TA2 2 +Platelet homeostasis 0.5018939211460258 1.0171769017400587 0.3090692821294356 1.0 0.8487132105347013 11 P16615,P63218,P20020,P04114,Q13586 5 +Diseases of glycosylation 0.429940947588031 1.0047657696304817 0.3150096501560124 1.0 0.8487132105347013 21 Q9BT22,P16278,Q9BV10,P06865,Q8NCH0,O60762,O43505 7 +Organic anion transporters 0.7916666666666491 1.0037154102264652 0.3155158070764434 1.0 0.8487132105347013 2 Q9UBX3 1 +Nephrin family interactions 0.5372168284789683 1.00134472637867 0.3166601765835362 1.0 0.8487132105347013 8 Q01082,O14936,Q9Y5K6,O00459,O43707,Q13813,P12814 7 +Cargo concentration in the er 0.4370438212505144 0.992640097550164 0.3208853767106694 1.0 0.8487132105347013 16 Q15363,Q5JRA6,O75396,Q96PC5,Q13190,O14653 6 +Transport to the golgi and subsequent modification 0.4066896425997747 0.9759285648150242 0.3290998655451647 1.0 0.8487132105347013 71 Q15363,Q9UJW0,Q5JRA6,Q9UP83,P24390,O95249,Q9BVK6,Q9BUF5,O75935,Q13561,Q96PC5,O60476,Q9BVA1,Q9Y3B3,O43731,O14653 16 +Chondroitin sulfate dermatan sulfate metabolism 0.598976319985568 0.9723666056317728 0.3308681990622972 1.0 0.8487132105347013 5 Q8NCH0 1 +Metabolism of steroids 0.3961062167221695 0.9702545805660842 0.3319196107616107 1.0 0.8487132105347013 47 Q53GQ0,P38435,Q9BWD1,P37268,Q15392,Q9HCL2,Q9BZK7,Q15800,Q9BZF3,Q16850,O76062 11 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.5168380700043236 0.962798198345608 0.3356488050567143 1.0 0.8493224587932374 9 Q9UJX6,Q96DE5,P30260,Q16763,Q9UJX3 5 +Post chaperonin tubulin folding pathway 0.5522616561178201 0.9589047622767806 0.3376067254599109 1.0 0.8514915012983361 7 P36404,Q9BVA1,Q9BUF5,Q99426 4 +Copi independent golgi to er retrograde traffic 0.4205002532427031 0.9546609697035724 0.3397491736770242 1.0 0.8553169805091935 22 Q9UJW0,Q9BUF5,O75935,Q9BVA1,Q15102 5 +Endosomal vacuolar pathway 0.7880452342487945 0.9419538264393668 0.3462162802782864 1.0 0.8652242324322076 3 Q9UIQ6,P10321 2 +Organelle biogenesis and maintenance 0.4003311573254089 0.9396470615854322 0.3473986278515169 1.0 0.8657489715166495 88 O94927,P00846,A6NIH7,P07437,Q9BUF5,Q96RR1,O75935,P06576,Q13561,Q5XKP0,P41208,O75964,Q9BZK7,Q9BVA1,Q10713,Q9H6D7,O75431,Q13505 18 +Mrna decay by 5 to 3 exoribonuclease 0.5121256687184065 0.9390737249015112 0.3476928934620633 1.0 0.8657489715166495 9 P62310,Q9Y4Y9 2 +Pyruvate metabolism 0.4260040027476304 0.9258311419888952 0.3545337403550868 1.0 0.86913787539613 17 P21796 1 +Trans golgi network vesicle budding 0.3773986321793228 0.9236655462669204 0.3556604756740245 1.0 0.86913787539613 33 Q9H3P7,P50570,P02786,O14976,Q9Y5X1,Q8NC96,O00203,O75976,O60749 9 +Synthesis of bile acids and bile salts 0.544456051279473 0.9230052115520264 0.3560044893402379 1.0 0.86913787539613 7 Q9BZF3 1 +Bile acid and bile salt metabolism 0.544456051279473 0.9230052115520264 0.3560044893402379 1.0 0.86913787539613 7 Q9BZF3 1 +Ub specific processing proteases 0.4003697146276439 0.9210975363752512 0.3569995063689126 1.0 0.86913787539613 66 O00231,P28074,P28072,P51665,P49721,P21796,P45880,P28070,Q15388,P20618,Q96K76,Q92530,Q14145,Q9Y277 14 +Pi metabolism 0.4249151074924136 0.9184704476856734 0.3583726236984286 1.0 0.86913787539613 17 Q8TBX8,Q10713,Q8IY17 3 +Golgi to er retrograde transport 0.3971592604894829 0.9013428864282728 0.3674060380513873 1.0 0.8765166736758226 62 Q15363,Q07866,Q9UJW0,P24390,Q9BVK6,P52732,Q6NUQ1,Q9BUF5,O75935,Q13561,Q9P2W9,Q9Y3B3,Q9BVA1,Q15102,Q12981,O43731 16 +Ldl clearance 0.4539794793002064 0.8810460085270174 0.3782929183264221 1.0 0.8906694094547681 13 Q6PIU2,O15118,P04114 3 +Reduction of cytosolic ca levels 0.6296634200990943 0.8805696570251099 0.3785507877785079 1.0 0.8906694094547681 4 P20020,P16615 2 +Pre notch expression and processing 0.4744380543683802 0.8673418674754612 0.385754723276495 1.0 0.8955375933980972 11 Q9UBV2,P16615 2 +Tp53 regulates transcription of cell death genes 0.6259351290872279 0.8660392648270705 0.3864686297328883 1.0 0.8955375933980972 4 Q13794 1 +Cargo recognition for clathrin mediated endocytosis 0.3796039519489083 0.8645718484648595 0.3872738294386375 1.0 0.8955375933980972 30 Q14108,Q9BT78,Q8NC96,P04114,Q99627 5 +Adrenaline noradrenaline inhibits insulin secretion 0.7657512116316665 0.8637539517130833 0.3877230688652149 1.0 0.8955375933980972 3 P63218,P04899 2 +Vesicle mediated transport 0.3199172385409643 0.8590843263589532 0.390293993954208 1.0 0.8966944064040296 227 O43752,Q07866,Q9UJW0,Q14108,P52732,P02786,Q6NUQ1,Q9NRW7,O00461,Q5VZ89,P31751,Q8N2H4,Q96PC5,P04114,Q12981,O60749,Q15363,Q9UIQ6,P24390,Q9UP83,Q8WTV0,Q9BT78,Q9Y5X1,Q9BVA1,O43731,Q15102,O75976,Q9H3P7,Q5JRA6,P50570,O60476,Q9Y3B3,Q5KU26,O00203,O14653,O95249,Q9BVK6,O14976,Q9BUF5,O75935,Q9P2W9,Q13561,P83436,Q8NC96,O60499,Q99627,P40616 47 +Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members 0.7512919896640619 0.850475182321436 0.3950609525943327 1.0 0.9046035547679276 2 Q13794 1 +Antigen processing cross presentation 0.3809230741352095 0.8158641152666729 0.4145778580786108 1.0 0.9126053655289228 49 Q03518,Q9UIQ6,Q99436,O00231,P28072,Q9UBG0,P28074,Q9UL46,P51665,P10321,P49721,P28070,Q92530,P20618 14 +Trna modification in the nucleus and cytosol 0.4868283372242878 0.8122838571717145 0.4166287712246657 1.0 0.9127107856796762 9 Q08J23,Q5VV42 2 +Tp53 regulates metabolic genes 0.3664476641434839 0.8048772422079662 0.4208905222655716 1.0 0.9137704050343128 35 P09669,P31751,P00403,O43819,O75880,P20674,Q9NQ88,P13073 8 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.5303180698676657 0.8014030050472367 0.4228983760297395 1.0 0.914718481064326 6 Q5KU26,P10321 2 +Biological oxidations 0.3720184198755283 0.7976474382496814 0.425075113894767 1.0 0.9150805015611536 41 P21964,P07099,Q9NUJ1,Q8TB61,Q16850,O43169,P30837,P78417 8 +Asparagine n linked glycosylation 0.37225095409589 0.7919590376429814 0.4283845611314407 1.0 0.9150805015611536 110 Q9UJW0,Q96PC5,Q15363,P24390,Q9BT22,Q9UP83,Q9BVA1,O60762,O43731,Q8WU17,Q5JRA6,P16278,Q9NR45,O60476,Q9Y3B3,Q86YN1,O14653,Q9UBV2,O95249,Q9BVK6,Q9BV10,Q9BUF5,O75935,Q13561,P83436,P10619,P46977 27 +Retrograde transport at the trans golgi network 0.4052002795944399 0.7856300554135912 0.4320842511466489 1.0 0.9150805015611536 17 O43752,Q9UP83,P83436,Q8N2H4,O60499 5 +Basigin interactions 0.5211988586972214 0.7615389374932479 0.4463352310757562 1.0 0.9201365396761704 6 P53985 1 +Ksrp khsrp binds and destabilizes mrna 0.4425813265489094 0.7557993219706631 0.4497695233355385 1.0 0.9205796346322296 12 Q5RKV6,O95453,Q9NQT5,Q96B26,Q13868 5 +Antigen presentation folding assembly and peptide loading of class i mhc 0.4125021090635498 0.755662383322179 0.449851642965859 1.0 0.9205796346322296 15 Q03518,Q9NZ08,P51572 3 +Adenylate cyclase inhibitory pathway 0.7322378056255163 0.7487936600981637 0.4539815815512651 1.0 0.924749980817946 3 P04899 1 +Er to golgi anterograde transport 0.3821437595579051 0.7403449266308442 0.459090726955206 1.0 0.9268962899294526 67 Q15363,Q9UJW0,Q5JRA6,Q9UP83,P24390,O95249,Q9BVK6,Q9BUF5,O75935,Q13561,Q96PC5,Q9Y3B3,Q9BVA1,O43731,O14653 15 +Heme signaling 0.4816840770382063 0.7340643659012481 0.462909510073429 1.0 0.9268962899294526 8 Q9BZK7,P09601 2 +Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.7189922480620196 0.7322659977729712 0.464006228696229 1.0 0.9268962899294526 2 P52292 1 +Camk iv mediated phosphorylation of creb 0.7189922480620196 0.7322659977729712 0.464006228696229 1.0 0.9268962899294526 2 P52292 1 +Long term potentiation 0.7189922480619928 0.7322659977728752 0.4640062286962876 1.0 0.9268962899294526 2 P07196 1 +Unblocking of nmda receptors glutamate binding and activation 0.7189922480619928 0.7322659977728752 0.4640062286962876 1.0 0.9268962899294526 2 P07196 1 +Ras activation upon ca2 influx through nmda receptor 0.7189922480619928 0.7322659977728752 0.4640062286962876 1.0 0.9268962899294526 2 P07196 1 +Negative regulation of nmda receptor mediated neuronal transmission 0.7189922480619928 0.7322659977728752 0.4640062286962876 1.0 0.9268962899294526 2 P07196 1 +Synthesis of substrates in n glycan biosythesis 0.4590440677762216 0.7306512595364564 0.4649921937129662 1.0 0.9268962899294526 10 Q9NR45,O60762,P16278,Q86YN1 4 +Potential therapeutics for sars 0.3567522557674077 0.7287732765780851 0.4661403608625385 1.0 0.9268962899294526 34 Q14145,Q99720,P07437 3 +Calnexin calreticulin cycle 0.4678702731749923 0.7182924472857355 0.4725769861042921 1.0 0.9268962899294526 9 Q8WU17 1 +Cellular response to chemical stress 0.3806933811288233 0.712443094304487 0.4761904378623676 1.0 0.9268962899294526 76 P30519,P00403,Q9BZK7,P20618,O75880,P33527,P51665,P28070,Q14145,P13073,P28072,P09601,P49721,Q92530,P20674,O00231,P28074,P09669,O43819 19 +Integrin cell surface interactions 0.5334535319629077 0.6994589709797299 0.4842652452974443 1.0 0.9268962899294526 5 Q08722 1 +Cilium assembly 0.3701970961287291 0.6962007127558426 0.486303141376283 1.0 0.9271195473299204 52 O94927,A6NIH7,P07437,Q9BUF5,O75935,P41208,Q9BVA1,Q10713,Q9H6D7 9 +Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.4494902510550109 0.6816878364371923 0.4954363603857388 1.0 0.9303042646254188 10 Q96DE5,Q16763,Q9UJX3 3 +Carboxyterminal post translational modifications of tubulin 0.7098546042003356 0.6742417598017287 0.5001576242558357 1.0 0.9353152836631016 3 Q9BVA1,Q9BUF5 2 +Perk regulates gene expression 0.409068646122077 0.6715528678145688 0.5018683920858185 1.0 0.937034975435642 14 Q5RKV6,O95453,Q9NQT5,Q96B26,Q13868,Q9Y3B2 6 +Dna strand elongation 0.3742729350170138 0.670642718888733 0.5024481616637348 1.0 0.937034975435642 25 Q9BRX5,P49005,P33991,P41440 4 +The role of gtse1 in g2 m progression after g2 checkpoint 0.357742734301071 0.6422866478270378 0.5206870820998128 1.0 0.9471772044965554 44 O00231,P28074,P28072,Q9BUF5,Q9UL46,P51665,P49721,P14635,P28070,Q9BVA1,Q92530,P20618 12 +Gpcr ligand binding 0.461501233020067 0.6391204738794338 0.5227445617789108 1.0 0.9471772044965554 8 Q9NRV9,P63218,P42892,P07602 4 +Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.4312567600940113 0.6353368873109193 0.5252087205620988 1.0 0.9471772044965554 11 Q9UJX6,Q96DE5,P30260,O60566,Q16763,Q9UJX3 6 +Apc cdc20 mediated degradation of nek2a 0.4312567600940113 0.6353368873109193 0.5252087205620988 1.0 0.9471772044965554 11 Q9UJX6,Q96DE5,P30260,O60566,Q16763,Q9UJX3 6 +Cross presentation of soluble exogenous antigens endosomes 0.3476252024106534 0.6269098077324351 0.5307183579275752 1.0 0.9533856822383756 36 O00231,P28074,P28072,Q9UBG0,P51665,P49721,P28070,Q92530,P20618 9 +Vitamin b5 pantothenate metabolism 0.5153710375417994 0.6268712989690575 0.5307436021824461 1.0 0.9533856822383756 5 P16260 1 +Ptk6 regulates proteins involved in rna processing 0.6898222940226162 0.6094004520267257 0.5422590383567119 1.0 0.9639377183792264 3 O75525,P23246 2 +Adora2b mediated anti inflammatory cytokines production 0.4543650716160774 0.606012732998918 0.5445062979969184 1.0 0.9654216723239786 8 P63218,P04899 2 +Ca2 pathway 0.551858782120897 0.5874023548253888 0.5569335126720141 1.0 0.9748921752634266 4 P63218,Q9HCE1 2 +Fatty acyl coa biosynthesis 0.373643498166408 0.5854816432874556 0.5582239060904863 1.0 0.9748921752634266 19 P50897,Q9UMR5 2 +Class a 1 rhodopsin like receptors 0.4779400827971246 0.5769541421540995 0.5639704343401291 1.0 0.9748921752634266 6 P42892,P07602 2 +Peptide ligand binding receptors 0.4779400827971246 0.5769541421540995 0.5639704343401291 1.0 0.9748921752634266 6 P42892,P07602 2 +Membrane trafficking 0.3011133047846898 0.5697823795456209 0.5688253080205927 1.0 0.9748921752634266 220 O43752,Q07866,Q9UJW0,Q14108,P52732,P02786,Q6NUQ1,Q9NRW7,O00461,Q5VZ89,P31751,Q8N2H4,Q96PC5,P04114,Q12981,O60749,Q15363,Q9UIQ6,P24390,Q9UP83,Q9BT78,Q9Y5X1,Q9BVA1,O43731,Q15102,O75976,Q9H3P7,Q5JRA6,P50570,O60476,Q9Y3B3,O00203,O14653,O95249,Q9BVK6,O14976,Q9BUF5,O75935,Q9P2W9,Q13561,P83436,Q8NC96,O60499,Q99627,P40616 45 +Runx3 regulates notch signaling 0.6705426356589156 0.5654655675410023 0.5717571380202819 1.0 0.9748921752634266 2 Q13573 1 +Notch4 intracellular domain regulates transcription 0.6705426356589156 0.5654655675410023 0.5717571380202819 1.0 0.9748921752634266 2 Q13573 1 +Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells 0.6705426356589156 0.5654655675410023 0.5717571380202819 1.0 0.9748921752634266 2 Q13573 1 +Interferon alpha beta signaling 0.4647116049936273 0.5652050198106394 0.5719343227251255 1.0 0.9748921752634266 7 P18031,P10321 2 +Transcriptional regulation by ventx 0.3814911470195005 0.5620304896758934 0.5740952458573947 1.0 0.9748921752634266 15 Q9UJX6,Q9HCE1,P35222,Q96DE5,P30260,Q16763,Q9UJX3 7 +Cytochrome p450 arranged by substrate type 0.6699339148668605 0.547092412044355 0.5843152450571654 1.0 0.975528171502259 3 Q16850 1 +Hedgehog ligand biogenesis 0.342787929663146 0.54459580771602 0.5860315387031672 1.0 0.975528171502259 40 Q9UBV2,O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 9 +Tp53 regulates transcription of genes involved in cytochrome c release 0.6682381256278249 0.5418850806698663 0.5878976751512615 1.0 0.975528171502259 3 Q13794 1 +Mismatch repair 0.4195054510749109 0.5311359793220793 0.5953245532845779 1.0 0.980042470123088 10 Q9UQ84 1 +Interleukin 12 signaling 0.3520191386418453 0.5228757991394194 0.6010606868674646 1.0 0.980042470123088 26 Q13126,P20700,P52597,P14174,P78417 5 +Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.356359101792527 0.519077740452042 0.6037065302576425 1.0 0.980042470123088 24 Q13126,P20700,P52597,P14174,P78417 5 +Sensory processing of sound by outer hair cells of the cochlea 0.3994034582649112 0.517614815846005 0.6047270425381472 1.0 0.980042470123088 12 Q14651,P35579,Q9Y2J2,Q00013,P23634 5 +Rho gtpase cycle 0.3055109486300831 0.5161677979930186 0.6057372190273178 1.0 0.980042470123088 144 O15173,P30519,Q96HY6,Q96F07,Q96RT1,Q9P0I2,P27105,Q9BT78,Q86XL3,O75976,Q13505,P50402,P51572,P08670,P51648,Q9UQB8,Q9BXS4,Q9Y6M7,P42167,Q07065,O95202,P20700,Q9UEY8,P41440 24 +Autophagy 0.3404945942417699 0.5057238683150271 0.6130505100766701 1.0 0.980042470123088 42 P21796,P08670,Q8N4H5,Q9NS69 4 +E2f enabled inhibition of pre replication complex formation 0.4565118426927184 0.489424724798519 0.62454103515786 1.0 0.9803580672611724 6 P14635 1 +Degradation of axin 0.3301202263190922 0.48416357091766 0.6282697881817629 1.0 0.9803580672611724 35 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Hedgehog on state 0.3357740872884436 0.4829348732715476 0.6291419794439097 1.0 0.9803580672611724 40 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618,O43791 9 +Regulation of runx3 expression and activity 0.3287979451217892 0.4622791262391114 0.6438811666015165 1.0 0.9834949209957446 36 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Activation of bh3 only proteins 0.3884848260728482 0.4595773265762021 0.6458196367634415 1.0 0.9853074145710096 12 P31751 1 +Asymmetric localization of pcp proteins 0.3280109613480435 0.4555031620218011 0.6487472932565685 1.0 0.9866153972853426 36 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Regulation of insulin secretion 0.385809308088805 0.4455393867327306 0.6559300028024184 1.0 0.988489398692708 12 P63218,P04899 2 +Rhob gtpase cycle 0.3513486811349935 0.43491767430752 0.6636221850925674 1.0 0.9925290229994964 18 P27105,Q96RT1,O75955,P41440 4 +Degradation of dvl 0.3240738342597185 0.4217622192413743 0.6731985848281772 1.0 1.0 36 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Regulation of ras by gaps 0.3240738342597185 0.4217622192413743 0.6731985848281772 1.0 1.0 36 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Metabolism of polyamines 0.3236798746561891 0.4184011590388187 0.6756538392932236 1.0 1.0 36 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Anti inflammatory response favouring leishmania parasite infection 0.3804748357700293 0.4177878570628804 0.6761022298181087 1.0 1.0 12 P63218,P04899,P63096 3 +Sulfur amino acid metabolism 0.3941493769141433 0.4091486335290123 0.6824305877005203 1.0 1.0 10 Q13126,Q9UBX3 2 +Neutrophil degranulation 0.2681804215473063 0.4079824730414346 0.6832865426035313 1.0 1.0 166 Q9H7Z7,P30519,O43681,Q9NQX7,P16278,Q93050,P42785,Q07065,P07602,P06280,Q13510,O00584,Q9BTY2,Q99536,Q5T9A4,P27105,P12956 17 +Rac1 gtpase cycle 0.3269097396898461 0.4060720888322333 0.6846896330917112 1.0 1.0 40 P42167,Q96F07,P02786,Q6IAA8,Q96RT1,Q15758,P50402,Q14344,Q9UQB8,Q9Y4F1,Q86Y07 11 +Polymerase switching 0.3635593391949961 0.4057574460627821 0.6849208284765309 1.0 1.0 14 P41440 1 +Cdc42 gtpase cycle 0.330883228081087 0.4049397669992005 0.6855217863238314 1.0 1.0 28 P42167,P02786,Q14344,A4D1P6,Q9Y4F1,P27105,Q9UQB8 7 +Cdt1 association with the cdc6 orc origin complex 0.3249448096308045 0.398927092597504 0.6899469257420172 1.0 1.0 39 Q9Y619,O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 9 +Stabilization of p53 0.3219995018582347 0.3938115358722974 0.693720186864681 1.0 1.0 37 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Signalling to ras 0.6127260981912188 0.3896824591680941 0.6967713687368466 1.0 1.0 2 P11233 1 +Tie2 signaling 0.6127260981912181 0.3896824591680914 0.6967713687368486 1.0 1.0 2 O00459 1 +Interleukin receptor shc signaling 0.6127260981912181 0.3896824591680914 0.6967713687368486 1.0 1.0 2 O00459 1 +Dap12 signaling 0.6129240710823853 0.3827971188836266 0.7018701978840216 1.0 1.0 3 P63000,O00459 2 +Regulation of pten stability and activity 0.3251973004355485 0.3818742829620822 0.7025546165226544 1.0 1.0 41 O00231,P28074,P28072,P51665,P31751,P49721,P28070,Q92530,P20618 9 +Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.4885200966359814 0.3745792968583419 0.7079733725397304 1.0 1.0 4 P67812 1 +Incretin synthesis secretion and inactivation 0.4885200966359814 0.3745792968583419 0.7079733725397304 1.0 1.0 4 P67812 1 +Butyrate response factor 1 brf1 binds and destabilizes mrna 0.3851479959653435 0.3674297374000567 0.7132984932258157 1.0 1.0 10 Q5RKV6,Q13868,Q9NQT5,Q96B26 4 +Class i peroxisomal membrane protein import 0.3695914257022294 0.3622443993113096 0.7171694034430796 1.0 1.0 12 O75381,O96011,Q9NR77,P51648,O43808,Q9Y3D6 6 +G1 s dna damage checkpoints 0.3190638278574839 0.3489752928364661 0.7271078583777775 1.0 1.0 39 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Interaction between l1 and ankyrins 0.478668390433098 0.3446228643121824 0.7303779144207381 1.0 1.0 4 Q12955,Q13813,Q01082 3 +Metabolism of folate and pterines 0.3946756054551145 0.34381837715583 0.730982878877567 1.0 1.0 8 P41440 1 +Methionine salvage pathway 0.4776977863544122 0.3417256684577412 0.732557353134075 1.0 1.0 4 Q13126 1 +Mastl facilitates mitotic progression 0.4744947639468198 0.3322357502365186 0.7397112506622054 1.0 1.0 4 P14635,P06493 2 +Polymerase switching on the c strand of the telomere 0.3334150203168626 0.3265101280549569 0.7440384277412453 1.0 1.0 16 P41440 1 +Activation of ampk downstream of nmdars 0.431361992570382 0.3199056687482889 0.7490398404804852 1.0 1.0 5 Q9BVA1 1 +G beta gamma signalling through pi3kgamma 0.5881209693653592 0.3193896886432822 0.74943102897489 1.0 1.0 3 P31751 1 +Miro gtpase cycle 0.469618616677442 0.3180014277835952 0.750483853871682 1.0 1.0 4 Q8IXI1,Q8IXI2,Q8IWA4 3 +Cellular response to hypoxia 0.31349298356264 0.3122484456952976 0.754851716929898 1.0 1.0 38 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Mitotic g2 g2 m phases 0.340310580628378 0.3082515927986909 0.7578908970575302 1.0 1.0 78 O94927,P07437,O00231,P28074,P28072,O75935,Q9BUF5,Q9UL46,P51665,P41208,P49721,P14635,P28070,Q92530,Q9BVA1,P20618,Q9H6D7 17 +Rho gtpases activate iqgaps 0.3845753704448455 0.3030254337716835 0.7618704789507962 1.0 1.0 8 Q9BVA1,P35221,Q9BUF5 3 +G1 s specific transcription 0.3702821291757688 0.3007633780335622 0.7635949361880376 1.0 1.0 10 Q9Y619,P12004,P31350,P04183,P00374 5 +Signaling by retinoic acid 0.3560328521238959 0.2953617455070582 0.7677175530477942 1.0 1.0 12 Q9BTZ2,Q9HBH5,P50416 3 +Interleukin 12 family signaling 0.3134840049994324 0.2948016954682281 0.7681453711709343 1.0 1.0 29 Q13126,P20700,P52597,P14174,P78417 5 +Cyclin a cdk2 associated events at s phase entry 0.3157583012383075 0.2926940624269756 0.7697560087403712 1.0 1.0 42 O00231,P28074,P28072,P51665,P31751,P49721,P28070,Q92530,P20618 9 +Ras processing 0.5766103418249289 0.2918902938168307 0.7703705049086467 1.0 1.0 3 O60725 1 +Regulation of hmox1 expression and activity 0.3184686307745256 0.2885496588910984 0.7729260237974662 1.0 1.0 45 O00231,P28074,P28072,P09601,P51665,P49721,P28070,Q92530,P20618,Q14145 10 +Abc transporter disorders 0.3159542448528619 0.28519045417036 0.7754982332967657 1.0 1.0 43 Q9UBV2,O00231,P28074,P28072,O14678,Q9UL46,P51665,P49721,P28070,Q92530,P20618 11 +Rna polymerase iii chain elongation 0.4579831932773126 0.2851122237507962 0.7755581653559052 1.0 1.0 4 O15160,P19388,P62875 3 +Rna polymerase iii transcription initiation from type 3 promoter 0.4579831932773126 0.2851122237507962 0.7755581653559052 1.0 1.0 4 O15160,P19388,P62875 3 +Signaling by the b cell receptor bcr 0.3144792563029132 0.2820383285734977 0.7779141208177038 1.0 1.0 42 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618,Q13586 9 +Deubiquitination 0.3367233754647263 0.2683714946197421 0.7884133789543093 1.0 1.0 83 O00231,P28074,P28072,O15294,P51665,P49721,P21796,P45880,P28070,Q15388,Q92530,Q96K76,P20618,Q14145,Q9Y277 15 +Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.3567384100385397 0.2665132824893867 0.7898439312684857 1.0 1.0 11 Q5RKV6,Q9NQT5,Q96B26,Q13868,Q9Y3B2 5 +Caspase mediated cleavage of cytoskeletal proteins 0.4509882309845395 0.2661010548811987 0.7901613826033591 1.0 1.0 4 P08670 1 +Abc family proteins mediated transport 0.3232720084279832 0.2659983933745135 0.7902404463662862 1.0 1.0 53 Q9UBV2,O00231,P28074,P28072,P51665,P49721,P28070,P08183,Q92530,P20618,P33527,O75027 12 +Role of phospholipids in phagocytosis 0.564781906300482 0.2649843476624189 0.7910215196961601 1.0 1.0 3 O00459,Q8IV08 2 +Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.5634614881960093 0.2620682223027924 0.7932688457066759 1.0 1.0 3 P67812 1 +Synthesis secretion and deacylation of ghrelin 0.5634614881960093 0.2620682223027924 0.7932688457066759 1.0 1.0 3 P67812 1 +Signaling by hedgehog 0.3214821816628772 0.2579308993424684 0.796460237266317 1.0 1.0 52 Q9UBV2,O00231,P28074,P28072,Q9UL46,P51665,P49721,P28070,Q9BVA1,Q92530,P20618,O43791 12 +Defective cftr causes cystic fibrosis 0.3112223473431026 0.2551034507041079 0.7986431990464025 1.0 1.0 42 Q9UBV2,O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 9 +Transcriptional regulation by runx3 0.3098673549291595 0.2532910924978403 0.8000432788905874 1.0 1.0 41 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Rnd2 gtpase cycle 0.3205796693728252 0.2491080341468364 0.8032772149703646 1.0 1.0 17 Q07065,P51648,P02786 3 +G protein beta gamma signalling 0.4080152555211608 0.2474643037804965 0.8045489139724173 1.0 1.0 5 P31751 1 +Ethanol oxidation 0.4394543763680876 0.2360636176464498 0.8133833050580108 1.0 1.0 4 P30837 1 +Adaptive immune system 0.2594008997611902 0.2316381074410149 0.8168191069141839 1.0 1.0 168 Q03518,Q07866,Q9UJW0,P31751,P20618,Q13586,Q9UIQ6,Q9UBG0,P51665,P10321,P28070,Q9BVA1,Q14145,Q8WWI1,P50570,P28072,Q9UL46,Q9NZ08,P49721,P55786,P51572,Q96PU5,Q5KU26,Q92530,O00231,P28074,Q9BUF5,O75935,Q13561,Q05086,Q9UJX3 31 +Activated ntrk2 signals through cdk5 0.5465116279069849 0.2308066633982512 0.8174650043505636 1.0 1.0 2 P63000 1 +Signaling by ntrk2 trkb 0.5466882067851276 0.2265964628271341 0.8207375430130219 1.0 1.0 3 P62993,P63000 2 +Nuclear envelope ne reassembly 0.3099221051042727 0.2263659898334585 0.8209167775953727 1.0 1.0 44 Q8N1F7,P42167,Q96EE3,Q9BTX1,Q9BUF5,P50402,P14635,Q86XL3,Q9BVA1,P20700,Q7Z3B4 11 +Regulation of kit signaling 0.4334195216548177 0.2210200606958561 0.8250768130366959 1.0 1.0 4 P62993,P07947,P07948 3 +Intraflagellar transport 0.3630920595244986 0.2209418614527807 0.8251377020238038 1.0 1.0 8 Q92973,Q9BVA1,Q9BUF5 3 +Runx3 regulates p14 arf 0.5368217054263653 0.2119786557006018 0.8321236862104961 1.0 1.0 2 P25440 1 +Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.5387659210376267 0.210877119510563 0.8329831586376124 1.0 1.0 3 P00374 1 +Signaling by notch2 0.5316537467700306 0.2024206592087536 0.8395878789697104 1.0 1.0 2 Q06330 1 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3102657000633403 0.1951944086080801 0.8452407561576423 1.0 1.0 48 Q99436,O00231,P28072,P28074,Q96DE5,Q9UL46,P51665,P49721,P28070,Q92530,P20618,Q9UJX3 12 +Negative regulation of the pi3k akt network 0.3324268513062789 0.1863830629741762 0.8521443735012681 1.0 1.0 12 P31751 1 +Gap junction trafficking and regulation 0.3477693537316082 0.1668486526669704 0.8674891359100885 1.0 1.0 8 Q9BVA1,P50570 2 +Dag and ip3 signaling 0.3641655886157751 0.1651571235132361 0.86882031222217 1.0 1.0 6 P13861,O43865,Q13555,P17252,P52292 5 +Activated tak1 mediates p38 mapk activation 0.5093669250646093 0.1650670078436061 0.8688912406786047 1.0 1.0 2 Q15750 1 +Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.5093669250646093 0.1650670078436061 0.8688912406786047 1.0 1.0 2 Q15750 1 +Pyruvate metabolism and citric acid tca cycle 0.2933860504605408 0.160944783058929 0.8721368902657423 1.0 1.0 37 P21796,Q13423 2 +N glycan trimming in the er and calnexin calreticulin cycle 0.3096624430127092 0.1575878492357445 0.8747815788337565 1.0 1.0 15 Q8WU17 1 +Downstream signaling events of b cell receptor bcr 0.2937984267591659 0.1542782362921147 0.8773903567809895 1.0 1.0 38 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Inla mediated entry of listeria monocytogenes into host cells 0.4987080103359222 0.1494056589052581 0.8812335466892585 1.0 1.0 2 P35222 1 +Epha mediated growth cone collapse 0.3547495922066949 0.1490618535020413 0.8815048260372962 1.0 1.0 7 Q15375,P60660,P35580 3 +Orc1 removal from chromatin 0.3037868243281109 0.1348408329862744 0.8927377205831106 1.0 1.0 49 Q9Y619,O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P33991,P20618 10 +Fcgr activation 0.4874031007752021 0.1343220886359522 0.8931478873116823 1.0 1.0 2 P07947 1 +Glucagon like peptide 1 glp1 regulates insulin secretion 0.3640478499838324 0.1320488283877571 0.8949456703968 1.0 1.0 5 P13861,P63218,P17252,P46940 4 +Aquaporin mediated transport 0.3640478499838299 0.1320488283877517 0.8949456703968042 1.0 1.0 5 P13861,P63218,P17252,Q99797 4 +Hedgehog off state 0.2973448719601831 0.1261018817824292 0.8996512779169015 1.0 1.0 44 O00231,P28074,P28072,Q9BUF5,Q9UL46,P51665,P49721,P28070,Q9BVA1,Q92530,P20618 11 +Signaling by erythropoietin 0.4875605815831965 0.1258675522380801 0.899836767922876 1.0 1.0 3 P62993,P46109 2 +Erythropoietin activates ras 0.4875605815831965 0.1258675522380801 0.899836767922876 1.0 1.0 3 P62993,P46109 2 +Fceri mediated ca 2 mobilization 0.4875605815831919 0.1258675522380737 0.8998367679228811 1.0 1.0 3 P62993,O43865 2 +Role of lat2 ntal lab on calcium mobilization 0.4875605815831912 0.1258675522380728 0.8998367679228818 1.0 1.0 3 P62993,O00459 2 +Pecam1 interactions 0.4875605815831866 0.1258675522380664 0.8998367679228869 1.0 1.0 3 P07947,P06756 2 +Switching of origins to a post replicative state 0.3100894938993566 0.1211052368546842 0.903607681299269 1.0 1.0 58 Q9Y619,O00231,P28074,P28072,Q9UL46,P51665,P49721,P28070,Q92530,P33991,P20618,Q9UJX3 12 +Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.3583279275174987 0.1192659864432833 0.9050646300051924 1.0 1.0 5 Q9BZK7,Q9HCE1 2 +Diseases of mitotic cell cycle 0.3119396874986181 0.1173155415216802 0.9066100097197856 1.0 1.0 13 Q96DE5,P30260,Q16763,Q9UJX3 4 +Gab1 signalosome 0.468023255813958 0.111998130333088 0.9108248890228334 1.0 1.0 2 P62993 1 +Negative regulation of notch4 signaling 0.2877369023616151 0.1083090543462242 0.9137505405401992 1.0 1.0 38 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Regulation of innate immune responses to cytosolic dna 0.4605943152454779 0.1045737986763563 0.9167140063131616 1.0 1.0 2 Q9NZI8 1 +Runx1 regulates transcription of genes involved in differentiation of hscs 0.2878986105415447 0.0999627431022548 0.9203739039419774 1.0 1.0 39 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.4521963824289424 0.0968997385075497 0.9228060164718968 1.0 1.0 2 P18887 1 +Syndecan interactions 0.3462657613966999 0.0940859354530007 0.925040892700948 1.0 1.0 5 P06756,O14936,P17252,P12814 4 +Neuronal system 0.292942607689356 0.0923811763586516 0.9263951945573954 1.0 1.0 44 P21964,P04899,Q9BUF5,P07196,O75955,O95197,Q9BVA1,O75915,P41440 9 +Constitutive signaling by egfrviii 0.452988691437791 0.0846580485368918 0.932533248600895 1.0 1.0 3 P62993,P07900 2 +Signaling by egfr in cancer 0.452988691437791 0.0846580485368918 0.932533248600895 1.0 1.0 3 P62993,P07900 2 +Constitutive signaling by ligand responsive egfr cancer variants 0.452988691437791 0.0846580485368918 0.932533248600895 1.0 1.0 3 P62993,P07900 2 +Vasopressin regulates renal water homeostasis via aquaporins 0.3639301874596015 0.0839368953058598 0.9331066048412 1.0 1.0 4 P63218,P17252,P13861 3 +Glucagon signaling in metabolic regulation 0.3639301874596015 0.0839368953058598 0.9331066048412 1.0 1.0 4 P63218,P17252,P13861 3 +Egfr transactivation by gastrin 0.4331395348837315 0.0821418719713892 0.9345338965890266 1.0 1.0 2 P62993 1 +Shc1 events in erbb2 signaling 0.4331395348837315 0.0821418719713892 0.9345338965890266 1.0 1.0 2 P62993 1 +Signaling by braf and raf1 fusions 0.2905447445553966 0.0804024026158051 0.9359172160822476 1.0 1.0 19 Q53H12,O00203,Q9NRY5 3 +M phase 0.2582470053542569 0.0786581584740901 0.9373045270166136 1.0 1.0 184 P57740,P20618,O94927,Q99436,Q9BTX1,P51665,Q86XL3,P14635,P28070,Q9BVA1,Q9H6D7,P07437,Q6IPU0,P50748,Q8N1F7,Q96EE3,P28072,Q9UL46,P50402,P49721,P41208,Q92530,Q6P1K2,Q8N3U4,P42167,O00231,P28074,Q9BUF5,O75935,Q96DE5,Q13561,P20700,Q7Z3B4,Q9UJX3 34 +G alpha 12 13 signalling events 0.3599363044297031 0.0781434836527462 0.9377139179710854 1.0 1.0 4 P63218 1 +Aggrephagy 0.3098245322537306 0.0775111329323908 0.9382169351202748 1.0 1.0 11 P08670,Q9BVA1 2 +Trna modification in the mitochondrion 0.3301921968582253 0.0772468742814272 0.9384271527342876 1.0 1.0 6 Q7L0Y3,O75648 2 +Visual phototransduction 0.3278841162213461 0.0720261731590592 0.9425810787719028 1.0 1.0 6 P04114 1 +Trafficking and processing of endosomal tlr 0.4063307493540034 0.0669113230801158 0.9466522987276114 1.0 1.0 2 Q99538 1 +Ret signaling 0.4332794830371509 0.0666301479862423 0.9468761444474116 1.0 1.0 3 P62993,O00459 2 +Interleukin 1 signaling 0.2845228411633278 0.0657505351077118 0.9475764382286788 1.0 1.0 40 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Dna damage recognition in gg ner 0.2896156321580697 0.0646358273530539 0.9484639582376856 1.0 1.0 15 Q9BT78 1 +Fructose metabolism 0.3934108527131765 0.0615319390171729 0.9509355789314315 1.0 1.0 2 Q00796 1 +Degradation of gli1 by the proteasome 0.2821602279693982 0.0579225011994631 0.9538103598442178 1.0 1.0 39 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Interleukin 7 signaling 0.4210016155088877 0.0572389489514501 0.9543548522271152 1.0 1.0 3 P40763,O00459 2 +Oncogenic mapk signaling 0.2855513940311804 0.0499267470809685 0.9601807627896608 1.0 1.0 22 Q99956,Q53H12,O00203,Q9NRY5 4 +Disassembly of the destruction complex and recruitment of axin to the membrane 0.3210475266731302 0.0493138469554568 0.9606691846694172 1.0 1.0 5 Q14738,P35222,P48729,P30153 4 +Beta catenin phosphorylation cascade 0.3210475266731302 0.0493138469554568 0.9606691846694172 1.0 1.0 5 Q14738,P35222,P48729,P30153 4 +Signaling by ctnnb1 phospho site mutants 0.3210475266731302 0.0493138469554568 0.9606691846694172 1.0 1.0 5 Q14738,P35222,P48729,P30153 4 +Nrage signals death through jnk 0.3361190355157591 0.0481765942515087 0.9615755036043376 1.0 1.0 4 Q92974,Q14344 2 +Fceri mediated nf kb activation 0.2831330912004508 0.0465674704156298 0.9628579587387476 1.0 1.0 41 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Tnfr2 non canonical nf kb pathway 0.2789265187799388 0.0442134499189872 0.9647342610530628 1.0 1.0 38 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Dectin 1 mediated noncanonical nf kb signaling 0.2789265187799388 0.0442134499189872 0.9647342610530628 1.0 1.0 38 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Cell death signalling via nrage nrif and nade 0.3143596377748955 0.0434267397771018 0.9653613625434584 1.0 1.0 6 Q92542,P63000,Q14344,Q92974,P62258 5 +Rhobtb3 atpase cycle 0.3938610662358568 0.040961547562435 0.9673265507177168 1.0 1.0 3 P51151,O60664 2 +Transcriptional regulation by runx2 0.2903971886344844 0.0398700712595866 0.968196711797858 1.0 1.0 48 O00231,P28074,P28072,P51665,P31751,P49721,P14635,P28070,Q92530,P20618 10 +Hdr through homologous recombination hrr 0.2798311684286239 0.0382142192047417 0.9695168838911996 1.0 1.0 27 Q9UQ84,P41440 2 +Interleukin 4 and interleukin 13 signaling 0.2947652891436302 0.0378074344926094 0.9698412167439188 1.0 1.0 12 P09601 1 +Rhobtb1 gtpase cycle 0.2807637646847379 0.0374662903714783 0.9701132176524324 1.0 1.0 18 Q9BT78 1 +G protein mediated events 0.299888197128663 0.0373804634968781 0.9701816496539531 1.0 1.0 10 P04899,P52292,P63096 3 +Prevention of phagosomal lysosomal fusion 0.3770597738287586 0.0335867902523883 0.9732066561776777 1.0 1.0 3 P51149,Q9H267 2 +Thrombin signalling through proteinase activated receptors pars 0.3743063882814048 0.0325503009768306 0.9740332028812584 1.0 1.0 3 P63218 1 +Zbp1 dai mediated induction of type i ifns 0.3660743134087226 0.029715047017392 0.9762943114366476 1.0 1.0 3 Q9NZI8,Q08211 2 +Rip mediated nfkb activation via zbp1 0.3660743134087226 0.029715047017392 0.9762943114366476 1.0 1.0 3 Q9NZI8,Q08211 2 +Scf skp2 mediated degradation of p27 p21 0.2790450299831851 0.0265508399904757 0.9788179834246944 1.0 1.0 40 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Signaling by notch4 0.2803201893056248 0.0265133769666942 0.9788478640738348 1.0 1.0 41 O00231,P28074,P28072,P51665,P49721,P28070,Q92530,P20618 8 +Hur elavl1 binds and stabilizes mrna 0.3067226890756323 0.0212887683006238 0.9830153034078566 1.0 1.0 4 Q15717,P17252,O14980 3 +Platelet aggregation plug formation 0.2942127384416343 0.0131402884359978 0.9895158684441944 1.0 1.0 5 P41240,Q9Y490,P18031,P62993 4 +Integrin signaling 0.2942127384416343 0.0131402884359978 0.9895158684441944 1.0 1.0 5 P41240,Q9Y490,P18031,P62993 4 +Uch proteinases 0.2817445696921909 0.0103775995409003 0.9917200221664992 1.0 1.0 44 O00231,P28074,P28072,O15294,P51665,P49721,P28070,Q92530,P20618 9 +Formation of tubulin folding intermediates by cct tric 0.2900950860616402 0.0093723440700731 0.9925220608461844 1.0 1.0 10 Q9BVA1,Q9BUF5 2 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..fe43b0637663d57b803ae9bd293ba08d18abc8ec --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of gene expression by srebf srebp", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pe", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha defensins", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd22 mediated bcr regulation", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate biosynthesis", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Chylomicron remodeling", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of particulate exogenous antigens phagosomes", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Dectin 2 family", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Defensins", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of base excision repair", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Elevation of cytosolic ca2 levels", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythrocytes take up carbon dioxide and release oxygen", "Erythropoietin activates phosphoinositide 3 kinase pi3k", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Erythropoietin activates stat5", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Ncam1 interactions", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O glycosylation of tsr domain containing proteins", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr regulates axonogenesis", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Phase 0 rapid depolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 24 hydroxycholesterol", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldl clearance", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc transporters"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APBB1", "APEH", "APEX1", "APLP2", "APOB", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8A", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3B", "ATG3", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATRIP", "ATRX", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BARD1", "BASP1", "BAX", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCKDHA", "BCKDHB", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BRCA1", "BRD1", "BRD2", "BRD4", "BSG", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "CAB39", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC22", "CCDC59", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA5", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2A", "CENPC", "CENPI", "CENPL", "CENPP", "CENPQ", "CENPU", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHST14", "CHTOP", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLNS1A", "CLSPN", "CLTB", "CLTC", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT9", "COA1", "COG2", "COG5", "COG6", "COG7", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ9", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC3", "DNAJC7", "DNAJC8", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLK", "DOLPP1", "DPM1", "DPYSL2", "DPYSL5", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHD1", "EHHADH", "EHMT1", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERLEC1", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESCO2", "ESD", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF2", "FAHD1", "FAM114A2", "FAM3C", "FAM49B", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FIP1L1", "FIS1", "FKBP14", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FOXK1", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "FYTTD1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GINS3", "GINS4", "GLA", "GLB1", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLS", "GLUD1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPI", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILK", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INCENP", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "ISCU", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIN9", "LIPA", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMO7", "LNPEP", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPPRC", "LRRC1", "LRRC8A", "LRRC8C", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LYN", "LYPLA1", "M6PR", "MAGED2", "MAGT1", "MAIP1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAPK1", "MAPRE1", "MARC1", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MFAP1", "MFN1", "MFN2", "MGAT1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYDGF", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1C", "MYO6", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAPA", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCOR1", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NLN", "NME1", "NMT1", "NNT", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN4", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCK2", "PCMT1", "PCNA", "PCYOX1L", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELP1", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "POFUT1", "POFUT2", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPID", "PPIE", "PPIH", "PPIL3", "PPIL4", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUS1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QTRT2", "RAB10", "RAB11B", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBBP7", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "REPS1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIPK1", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPS1", "RP2", "RPA1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP36", "RRP7A", "RRP8", "RRP9", "RSF1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SC5D", "SCAMP1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35B2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLIT2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX9", "SOAT1", "SOD2", "SORD", "SPAG9", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPOP", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX10", "STX18", "STX3", "STX5", "STX6", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SYMPK", "SYNE2", "SYS1", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL3", "TCEA1", "TCP1", "TDRKH", "TECR", "TERF2", "TERF2IP", "TEX10", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TLE3", "TLN1", "TM7SF2", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM126B", "TMEM59", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMX3", "TNPO1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRMT1", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSG101", "TSN", "TSNAX", "TST", "TTC26", "TTC37", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAP1", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBIAD1", "UBN1", "UBR4", "UBTF", "UCHL5", "UFD1", "UFL1", "UGGT1", "UHRF1", "UMPS", "UNC119B", "UPF1", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USO1", "USP10", "USP14", "USP19", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WBP11", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WFS1", "WIPI2", "WTAP", "XAB2", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZMYM2", "ZNF512B", "ZNF638", "ZW10", "ZWILCH"], "leading_proteins": ["ABCB1", "ABCB7", "ABCC1", "ABCD4", "ABHD10", "ACAT2", "ACBD3", "ACOT8", "ACOX3", "ACP6", "ACTN1", "ACTN4", "ADD1", "ADD3", "AGK", "AGPAT1", "AHCYL1", "AKAP1", "AKT2", "ALDH1B1", "ALDH3A2", "ALG1", "ALG12", "ALG2", "ANAPC16", "ANAPC2", "ANAPC7", "ANK3", "ANKLE2", "ANO6", "AP3B1", "APOB", "ARHGEF2", "ARL1", "ARL2", "ARL6IP5", "ASAH1", "ASNA1", "ATAD3B", 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4.538458527560961 1.9412236823915887 0.3642771965747766 0.0048236448060394 7.092195860576647e-05 0.0002464951554534 1.1550137002587494e-05 2.87785716218875e-07 +Nephrotic syndrome 2 10 2.2860016447194123 0.0222541623395151 2.8009708737864076 13.016990291262136 0.5944173315199666 0.4060428580487139 1.745785223816307 1.64204545361887 0.9786485639177428 0.2829862039354683 0.0188740973653811 0.1471951297158956 0.0405463165390607 0.0449350347407693 0.2143350029099695 +Oxidation by cytochrome p450 3 6 2.039279385613798 0.0414221518263981 2.3179611650485437 5.422330097087379 1.262256455948566 0.1900711291682963 1.161003800051733 0.6764315332620536 1.214909583878196 0.2447393771863318 0.0203954716413504 0.0607401038440192 0.0067896670197663 0.0382400085743442 0.0027630263410089 +Mitochondrial complex i assembly model oxphos system 11 31 2.000161770551085 0.0454827984251728 8.808252427184467 26.563106796116504 0.7827212026364002 0.3851038550171766 4.050605834390814 3.9632288075289823 1.2210776523685654 0.3331428769936953 0.0661623524228265 0.0276250495673642 0.0965403494275516 0.0413751204339429 0.001050513287845 +Sphingolipid metabolism in senescence 4 13 1.973548043819726 0.0484331565050655 4.349514563106796 11.679611650485436 1.1898351622318797 0.2087194733713789 1.8732078185138223 1.4259290429724831 1.4063103725171229 0.2533781048666968 0.0069459336161985 1.0 0.2012104780589677 0.0173886328284286 0.0042957165481444 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5ea0ba6fd43788bad8d0409edc9197b494fa9555 --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 591, + "title": "Average number of proteins per term", + "value": 9.839255499153976 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..bb657ac2cd10ff850ccd3d1937755b5ffe331d35 --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4573282128f87c92e88256057df1c9b5f10d2c1b --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,123 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial complex iv assembly 0.8325111334211366 2.71635822219948 0.0066004458411039 0.980035391366844 0.2208619422589615 11 P14406,Q9Y2R0,P00403,O43819,P20674,Q7KZN9,P13073 7 +Electron transport chain oxphos system in mitochondria 0.5578168407657632 2.385174428295708 0.017071025096105 0.9999619299691022 0.2508273996869314 55 O43676,P00846,O95182,P22695,O96000,O14949,P14406,O95168,P06576,P09669,P00403,O75964,P03886,P20674,Q9UDW1,Q7KZN9,P13073 17 +Nephrotic syndrome 0.765215807302299 2.2860016447194123 0.0222541623395151 0.9999983267851916 0.3058653475035688 10 O75844,Q14108 2 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.9259235654327508 2.0498555899653597 0.0403785250116708 0.999999999973632 0.408843841613052 4 P07099,P09601 2 +Oxidation by cytochrome p450 0.8119758292585973 2.039279385613798 0.0414221518263981 0.9999999999861392 0.408843841613052 6 O43169,Q6UW02,Q16850 3 +Mitochondrial complex i assembly model oxphos system 0.5080398984636076 2.0001617705510855 0.0454827984251728 0.9999999999988722 0.440661210971757 31 O43676,O96000,O95182,O95168,Q96CU9,Q9NPL8,Q8TB37,P03886,Q9Y375,Q9P0J0,O75380 11 +Sphingolipid metabolism in senescence 0.6415313296428267 1.973548043819726 0.0484331565050655 0.999999999999819 0.4524964938601792 13 Q06136,Q13510,P16278,Q96G23 4 +Sphingolipid metabolism integrated pathway 0.7619011218624283 1.910664303784074 0.0560477349136183 0.9999999999999984 0.4892097682355456 7 O95470,Q13510,Q06136,Q96G23 4 +Sphingolipid metabolism overview 0.7619011218624283 1.910664303784074 0.0560477349136183 0.9999999999999984 0.4892097682355456 7 O95470,Q13510,Q06136,Q96G23 4 +Statin inhibition of cholesterol production 0.7607613071628377 1.905674694493234 0.056692424445901 0.999999999999999 0.4892097682355456 7 Q14534,P37268,Q8WTV0 3 +Familial partial lipodystrophy fpld 0.7572334654391183 1.8902145878480516 0.0587292664532101 0.9999999999999996 0.4958428067692461 7 O75844,O60725,P31751,P20700 4 +Sphingolipid pathway 0.7026975626066647 1.8838930024078713 0.0595794499589044 0.9999999999999998 0.4959359848691902 9 O95470,Q13510,Q06136,Q96G23 4 +Glycosaminoglycan degradation 0.803965275201333 1.84041350410614 0.0657075523721391 1.0 0.5109626769991343 5 P54802,P16278 2 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.5306295473794496 1.8176038847359532 0.0691246974632082 1.0 0.5252838723064378 24 Q9BWD1,Q14534,P37268,Q15392,Q15800,Q16850,O76062 7 +Transcriptional activation by nrf2 in response to phytochemicals 0.7902033850154724 1.783424717307742 0.0745171926440835 1.0 0.5381582442331427 5 P09601 1 +Influence of laminopathies on wnt signaling 0.7202620591608917 1.726703276913523 0.0842209668569513 1.0 0.5466616498176617 7 O75844,O60725 2 +Oxidative phosphorylation 0.4666321028924528 1.6937502640596898 0.0903127486953752 1.0 0.5466616498176617 35 O96000,P00846,O95182,O95168,P06576,O75787,O75964,P03886,O75380,Q86Y39 10 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.6041629285089241 1.6696482485096968 0.0949889784127169 1.0 0.567055416585007 12 O75844,P55209,O60725,P50402 4 +Striated muscle contraction pathway 0.7222533127838643 1.654387098578448 0.0980488861193047 1.0 0.573588216958772 6 P08670,P28289,P67936 3 +Nucleotidebinding oligomerization domain nod pathway 0.7135653581809919 1.616371948064501 0.1060139196142204 1.0 0.5815911681165372 6 Q9P0J0 1 +Mitochondrial complex iii assembly 0.6457071315992924 1.6077403361064313 0.1078920604695152 1.0 0.5815911681165372 9 Q6DKK2,Q9UDW1,P22695 3 +1q211 copy number variation syndrome 0.6237603032147718 1.5883073508094692 0.1122168561034313 1.0 0.5815911681165372 10 Q9NPH0 1 +Ciliopathies 0.5567005913756409 1.574680976596375 0.1153301010112983 1.0 0.5875869801523909 14 Q10713,Q9NVR5,Q13432 3 +Triacylglyceride synthesis 0.7293709280470455 1.5283092075228295 0.1264357849122568 1.0 0.607508527505234 5 Q9HCL2 1 +Degradation pathway of sphingolipids including diseases 0.6826663436618509 1.4802597399362096 0.1388039430343051 1.0 0.6081916726154011 6 P06280,O43681,P16278 3 +Nrf2are regulation 0.6349023934544693 1.4738234535188728 0.1405291318075456 1.0 0.6081916726154011 8 P09601 1 +S1p receptor signal transduction 0.6628295713049162 1.4677340099670173 0.1421764886872432 1.0 0.6081916726154011 7 Q13510,P31751 2 +Cholesterol biosynthesis with skeletal dysplasias 0.678577438966496 1.462150661344758 0.143699928511773 1.0 0.6081916726154011 6 Q16850 1 +Nonalcoholic fatty liver disease 0.452427246135765 1.4607921985904235 0.1440724774385045 1.0 0.6081916726154011 52 O43676,O96000,O95182,P22695,O14949,P14406,O95168,P31751,P00403,P20674,Q9UDW1,Q9P0J0,P13073 13 +Progeriaassociated lipodystrophy 0.6151988926620844 1.4570211163921654 0.145110551376959 1.0 0.608229332367254 9 O75844,O60725,P20700 3 +Metapathway biotransformation phase i and ii 0.4879875780498665 1.4457850581009828 0.1482374982999814 1.0 0.6088924864232007 22 P07099,Q8NCH0,Q6UW02,Q16850,P78417 5 +Urea cycle and related diseases 0.8959948320413444 1.4145194577391302 0.1572094384329552 1.0 0.6088924864232007 2 Q9UJS0 1 +Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway 0.9138234102190606 1.3961176174005574 0.1626790794385275 1.0 0.6088924864232007 3 P09601 1 +Ketogenesis and ketolysis 0.6391325985582178 1.3594092460230935 0.1740169428494375 1.0 0.6348395878025779 7 O43772,P53985 2 +Copper homeostasis 0.6524076971446396 1.3457997133272026 0.1783671179213288 1.0 0.6456021228320926 6 O75880,O43819,P35670 3 +Endothelin pathways 0.631749814348741 1.3255230595879404 0.184997726355562 1.0 0.6534282947462307 7 P16615,P42892 2 +Metabolism of spingolipids in er and golgi apparatus 0.8730620155038769 1.323268466761632 0.1857461142425833 1.0 0.6534282947462307 2 Q06136 1 +Irinotecan pathway 0.8682170542635526 1.3040262306252997 0.1922246390144024 1.0 0.655359472977567 2 O15118 1 +Primary focal segmental glomerulosclerosis fsgs 0.4734203609169732 1.2350907623859035 0.2167967269723822 1.0 0.7099137993313637 16 Q14108 1 +7oxoc and 7betahc pathways 0.5523266302779385 1.2181832840425804 0.2231543304466257 1.0 0.7206787393112338 10 O14734,O15118 2 +Relationship between inflammation cox2 and egfr 0.8479288275542162 1.156455130283144 0.2474950426358075 1.0 0.7483765536041663 3 Q9H7Z7 1 +Mirna regulation of p53 pathway in prostate cancer 0.6973658001616204 1.1486299085632092 0.2507086189271019 1.0 0.7483765536041663 4 O14681,Q13794 2 +Translation factors 0.4000753992905944 1.1263818456156698 0.2600039277460555 1.0 0.7609747521294556 33 O75153,P55010 2 +Cholesterol biosynthesis pathway 0.5025275171490322 1.096915471703305 0.2726783447317824 1.0 0.7609747521294556 12 Q14534,P37268,Q15800,Q16850 4 +Acquired partial lipodystrophy barraquersimons syndrome 0.6826085648374209 1.0897297991179318 0.2758321854946093 1.0 0.7642989511427262 4 O60725,P20700 2 +Overview of nanoparticle effects 0.8133074935400328 1.0876464246049766 0.2767512276557418 1.0 0.7642989511427262 2 P09601 1 +Sterol regulatory elementbinding proteins srebp signaling 0.3913955138643388 1.059244720434288 0.2894883432072601 1.0 0.7819844565361538 32 P37268,Q16850,Q9HCL2,Q8WTV0 4 +Mrna protein and metabolite inducation pathway by cyclosporin a 0.8193938296685086 1.0536095002915935 0.2920617378368939 1.0 0.782390341398626 3 Q14145 1 +Head and neck squamous cell carcinoma 0.4776341486382838 1.0216331679565456 0.3069545532572535 1.0 0.7957957429816919 13 P31751 1 +Adipogenesis 0.4511678680053934 1.0024515457987082 0.316125557497886 1.0 0.7957957429816919 15 O75844,Q9NR56,P14174,P43490 4 +Allograft rejection 0.535887957414112 0.9948949477573588 0.319787360349383 1.0 0.7957957429816919 8 P08670,P08183 2 +Camkk2 pathway 0.5196727695170407 0.9770795539685928 0.3285297691043207 1.0 0.7957957429816919 9 P09601 1 +Vitamin dsensitive calcium signaling in depression 0.556160858493434 0.9768630997581176 0.3286369321200542 1.0 0.7957957429816919 7 P00390,P20020,P23634 3 +Mevalonate arm of cholesterol biosynthesis pathway 0.5195230230024851 0.9763249561432856 0.3289034566184152 1.0 0.7957957429816919 9 P37268,Q9BWD1 2 +Eicosanoid metabolism via lipooxygenases lox 0.5697040263959802 0.9758186243563975 0.3291543536787213 1.0 0.7957957429816919 6 O15254 1 +Hostpathogen interaction of human coronaviruses apoptosis 0.7774547803617577 0.9492090926955136 0.3425142779164638 1.0 0.7961070138081882 2 Q07812 1 +Tp53 network 0.6457701603392239 0.9437037566478018 0.3453210537832585 1.0 0.7961070138081882 4 Q13794 1 +Apoptosis modulation and signaling 0.4586530523083905 0.9087713583110214 0.3634708282265784 1.0 0.7961070138081882 13 O95817,Q07812,O43464,O95831,Q13794 5 +Prostaglandin and leukotriene metabolism in senescence 0.7655038759689967 0.9038254098382948 0.3660879858069905 1.0 0.7961070138081882 2 P09960 1 +Myometrial relaxation and contraction pathways 0.4234158150687671 0.9017715220203886 0.3671782505752614 1.0 0.7961070138081882 16 P78417 1 +Cancer immunotherapy by pd1 blockade 0.7512919896640827 0.8504751823215128 0.3950609525942901 1.0 0.8214938020304346 2 P04439 1 +Familial hyperlipidemia type 4 0.6184304263359166 0.8368995703508763 0.4026490218976886 1.0 0.8214938020304346 4 Q9UBV2 1 +Alzheimers disease and mirna effects 0.3923107871856464 0.8317395438922834 0.4055559749036019 1.0 0.8214938020304346 72 P07437,Q07866,P16615,P28074,P28072,Q9BUF5,Q9NQC3,O95197,P51665,P31751,P49721,P21796,P45880,P28070,Q9BVA1,P20618,Q9Y277 17 +Alzheimers disease 0.3868401352839087 0.7784400444274486 0.4363096391882013 1.0 0.822206527464113 71 P07437,Q07866,P16615,P28074,P28072,Q9NQC3,O95197,P51665,P31751,P49721,P21796,P45880,P28070,Q9BVA1,P20618,Q9Y277 16 +Folate metabolism 0.4149232045242846 0.7710004638619962 0.4407066566473816 1.0 0.822206527464113 15 Q8NFF5,P41440,Q8WTV0 3 +Purinergic signaling 0.7322378056255163 0.7487936600981637 0.4539815815512651 1.0 0.8288746830078851 3 P04899 1 +Methionine de novo and salvage pathway 0.4688878806338828 0.723306637719087 0.4694915156806143 1.0 0.8288746830078851 9 Q13126,Q9BV57 2 +Nanomaterial induced apoptosis 0.5385954317810897 0.7203774705445232 0.4712926175773115 1.0 0.8288746830078851 5 O95831,O43464 2 +Selenium micronutrient network 0.4299882515760962 0.6852399557064668 0.4931925144679501 1.0 0.8311305290309705 12 Q8NFF5,P04114,Q8WTV0 3 +P53 transcriptional gene network 0.4459138050117731 0.6634623813234121 0.5070344648766552 1.0 0.8411397895351934 10 Q9NQ88,Q07812,Q13794 3 +Metabolic pathway of ldl hdl and tg including diseases 0.5689648212961274 0.6496048851258386 0.5159474767480887 1.0 0.8470137743281122 4 Q8WTV0 1 +Complement system in neuronal development and plasticity 0.4572806735758614 0.6195062811735266 0.5355828853170612 1.0 0.8645001968487889 8 Q5KU26,O43464 2 +Heme biosynthesis 0.5588897200349536 0.6127740207566289 0.5400257709914762 1.0 0.8649193242709009 4 P22830 1 +Dna damage response 0.3691861228685488 0.5830837463847923 0.559836924832541 1.0 0.8786571432600234 22 P14635,Q13794,P41440,Q9BXW9 4 +Modulators of tcr signaling and t cell activation 0.4361184959817771 0.564297687117801 0.572551555219412 1.0 0.8803273778589846 9 O96000 1 +Proteoglycan biosynthesis 0.4984973615759738 0.5607492709822012 0.5749684735254958 1.0 0.8803273778589846 5 Q8NCH0 1 +Ferroptosis 0.3619273269466833 0.5318463788910963 0.594832397756492 1.0 0.896297231003801 22 P16435,P37268,P09601,P45880,Q9Y277 5 +Male infertility 0.3645976910412947 0.5248872811348719 0.5996615516379715 1.0 0.896297231003801 19 P08183,Q15165 2 +G protein signaling pathways 0.3878858939174363 0.4980687908187511 0.6184355569263087 1.0 0.896297231003801 13 O43823,P04899,Q92667,P63218,Q14344 5 +Mirna regulation of dna damage response 0.3548683284132145 0.4941921898586555 0.6211704550116988 1.0 0.897583713721061 23 P14635,Q13794,P41440,Q9BXW9 4 +Joubert syndrome 0.3605114916692719 0.4915559837360387 0.6230332663228362 1.0 0.898079659504381 16 Q13432,P41208 2 +Dna mismatch repair 0.3573713303201127 0.4771047500764501 0.6332875323840472 1.0 0.8983804010888795 19 Q9UQ84,P41440 2 +Nuclear receptors metapathway 0.342863101080038 0.4679334019698281 0.6398322161068981 1.0 0.8983804010888795 49 P09601,Q9HCL2,P08183,P27105,Q14145 5 +Mitochondrial long chain fatty acid betaoxidation 0.3639244909758702 0.4558258671961036 0.6485152015217266 1.0 0.8983804010888795 15 O43772,P23786 2 +H19 action rbe2f1 signaling and cdkbetacatenin activity 0.4688758067123436 0.4494467957260072 0.6531093803228936 1.0 0.8983804010888795 5 Q15648,P11802,Q13794 3 +Glycerophospholipid biosynthetic pathway 0.4020746649584875 0.4466210558917602 0.655148690088974 1.0 0.8983804010888795 10 Q9HCL2 1 +Vitamin d receptor pathway 0.3752426091740149 0.4284553946939639 0.6683196018730366 1.0 0.8983804010888795 13 P08183,Q5VV42 2 +Nad metabolism sirtuins and aging 0.6095011814551018 0.3737249566710528 0.7086089558489652 1.0 0.9120265486365866 3 P43490 1 +Ccl18 signaling pathway 0.373142927741361 0.3421541329869401 0.7322349008566338 1.0 0.9306469385081088 11 P08670,P07196 2 +Genes related to primary cilium development based on crispr 0.3860205381528278 0.3366106158321153 0.7364104525060704 1.0 0.931680290378362 9 Q96J42,Q10713,Q9C0F1 3 +Phosphoinositides metabolism 0.4036050631268232 0.2906917562174111 0.7712870770584761 1.0 0.955619837613332 6 Q8TBX8 1 +Synaptic signaling pathways associated with autism spectrum disorder 0.3735054763536465 0.2598820802956398 0.7949547343283927 1.0 0.9593842420344626 8 P31751 1 +Cytosolic dnasensing pathway 0.3667853674328105 0.2568181576846799 0.7973191522846419 1.0 0.9593842420344626 9 Q9NZI8,Q7Z434,P19388,O14802,O15160,Q14258,P62875,P55265 8 +Histone modifications 0.3597686921408722 0.2555273637393185 0.798315811708223 1.0 0.9593842420344626 10 Q15047 1 +Thermogenesis 0.3114022072540334 0.2432646594710439 0.8078003798235582 1.0 0.9593842420344626 27 O43772,P23786 2 +Tyrobp causal network in microglia 0.4362333648324441 0.227975698571494 0.8196651328242148 1.0 0.9630657922447534 4 Q15758 1 +Ethanol effects on histone modifications 0.3438409188796852 0.210142455704884 0.8335564903350647 1.0 0.9678426046915978 11 Q9H9T3,P41440,P00374 3 +Amyotrophic lateral sclerosis als 0.357887428906216 0.2021230451651965 0.8398205322281476 1.0 0.9698728800487804 8 P07196,Q07812,P07197 3 +Type i collagen synthesis in the context of osteogenesis imperfecta 0.3400866515290462 0.194307322463152 0.8459352524079213 1.0 0.9698728800487804 11 O75718,Q32P28 2 +Novel intracellular components of rigilike receptor rlr pathway 0.3665480427046197 0.186162691226858 0.8523171805650465 1.0 0.970557714285053 7 Q7Z434,Q92841,O00571,Q13573,Q13526,Q14258 6 +Genes controlling nephrogenesis 0.3698370220650329 0.1817570428179795 0.8557733977664197 1.0 0.9719440927148844 6 O94813 1 +Hepatitis c and hepatocellular carcinoma 0.3646069233257732 0.179900448128788 0.8572307233856205 1.0 0.9719440927148844 7 P40763,Q14247,P63000,P31350,P62993,P38398 6 +Development of ureteric collection system 0.378788321799425 0.1674342329263229 0.8670283913662928 1.0 0.9741706830750552 5 O94813 1 +Nucleotide excision repair 0.3040022264758231 0.15061639123957 0.8802783305637509 1.0 0.9806114881936434 21 P41440,P41208 2 +Proteasome degradation 0.2927293963019465 0.1364191075894604 0.8914899692121643 1.0 0.988500134717428 39 O00231,P28074,P28072,Q9UL46,P51665,P10321,P49721,P28070,P20618,P04843 10 +Mammary gland development pathway involution stage 4 of 4 0.4897469856213082 0.1289054309634341 0.8974324792394504 1.0 0.9913693368794676 3 Q07812 1 +Nsp1 from sarscov2 inhibits translation initiation in the host cell 0.3133149469437077 0.1231864665481664 0.901959442072482 1.0 0.9928660462210182 13 O00303,O15372,P55010 3 +Autosomal recessive osteopetrosis pathways 0.4764211886304902 0.1211364094394986 0.9035829909478352 1.0 0.9928660462210182 2 P51798 1 +Regulation of apoptosis by parathyroid hormonerelated protein 0.3752264640562316 0.1015498688348071 0.9191139725208132 1.0 0.9985227164702218 4 Q9BXK5,Q07812 2 +Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.3462657613966944 0.0940859354529898 0.9250408927009566 1.0 0.999579667812348 5 Q13418,Q15118,P06730,P42345 4 +Hedgehog signaling pathway wp47 0.4127906976744201 0.070049021121155 0.9441546422202312 1.0 1.0 2 O00422 1 +Microrna network associated with chronic lymphocytic leukemia 0.3640180878552974 0.0530277038172763 0.9577098343071038 1.0 1.0 2 Q07820 1 +Mammary gland development pathway embryonic development stage 1 of 4 0.3459302325581372 0.0497889457771561 0.960290575750694 1.0 1.0 2 O60315 1 +Complement and coagulation cascades 0.345284237726095 0.0496953109279573 0.9603651931818864 1.0 1.0 2 P49257 1 +Mecp2 and associated rett syndrome 0.2847929146312163 0.0463039209746773 0.9630680141774356 1.0 1.0 21 Q03518,P52597,Q05086,P67809,P31943,Q00013 6 +Endometrial cancer 0.2964798013146552 0.0328737669770905 0.9737752524052156 1.0 1.0 11 Q07812,P35222,P35221,P31751,Q13418 5 +Cellular proteostasis 0.3071066385897544 0.0215742584713907 0.9827875675157796 1.0 1.0 4 O60925 1 +Interactions between loxl4 and oxidative stress pathway 0.3295638126009714 0.0211366353712046 0.9831366606161605 1.0 1.0 3 Q9BQ95,Q16543 2 +Ptf1a related regulatory pathway 0.2969305331179334 0.0174020943260819 0.9861158383785784 1.0 1.0 3 P35222,Q06330 2 +Chemokine signaling pathway 0.2758115562769337 0.0149989117821175 0.9880330485574548 1.0 1.0 18 P63218,P04899,P31751,P63096 4 +Calcium regulation in cardiac cells 0.2773419466303138 0.0080849782786039 0.9935491909353557 1.0 1.0 23 P04899,P16615,P08133,P63218,P20020,P63096,P23634 7 +3q29 copy number variation syndrome 0.2920439844760617 0.0037111899999854 0.9970389055939656 1.0 1.0 6 Q09161,P02786,Q96FJ2,P61088,P52298 5 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ccca6d183bd84c93ea1f88934d3ef155e50188ef --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Ganglio sphingolipid metabolism", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes associated with the development of rheumatoid arthritis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpr143 in melanocytes and retinal pigment epithelium cells", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactions of natural killer cells in pancreatic cancer", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoblast signaling", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAR2", "AARS", "AASS", "ABAT", "ABCB1", "ABCC1", "ABCD3", "ABCF1", "ABCF2", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANXA1", "ANXA2", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APBB1", "APEX1", "APLP2", "APMAP", "APOB", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARL8B", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATIC", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AURKA", "AURKB", "B3GAT3", "BAG2", "BAG3", "BAG4", "BAIAP2", "BAK1", "BANF1", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BCAS3", "BCAT2", "BCKDHA", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BLM", "BLVRA", "BMI1", "BPTF", "BRCA1", "BRD1", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "C1QBP", "CAAP1", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CANT1", "CAP1", "CAPN1", "CAPN2", "CAPZB", "CARM1", "CASK", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR2", "CCDC124", "CCDC6", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC73", "CDCA5", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2A", "CEBPZ", "CECR2", "CELF1", "CELF2", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHMP6", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CIP2A", "CKB", "CLASP1", "CLCN7", "CLIC1", "CLPTM1L", "CLSPN", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT9", "CNP", "COA1", "COA3", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COQ8A", "COQ9", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPT1A", "CPT2", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DARS", "DCAF1", "DCAF7", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DECR1", "DEK", "DERL1", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX36", "DHX38", "DHX8", "DHX9", "DIAPH1", "DLAT", "DLD", "DLST", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DOLK", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC1", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHD1", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMD", "ENAH", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPRS", "EPS15", "ERBIN", "ERCC3", "ESCO2", "ESD", "ESS2", "ETF1", "ETFA", "ETFDH", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOSC2", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAM120A", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIS1", "FKBP10", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FOXRED1", "FSCN1", "FTL", "FTO", "FUCA1", "FUS", "FXR1", "G3BP1", "G6PD", "GABARAPL2", "GAPDH", "GART", "GBA", "GCDH", "GCLC", "GDAP1", "GGCT", "GGCX", "GGH", "GID8", "GIGYF2", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GM2A", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPI", "GPS1", "GPT2", "GRB2", "GRSF1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F2", "GTF2I", "GTPBP4", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOXD11", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP3", "ILF2", "ILK", "IMPAD1", "IMPDH2", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIDINS220", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF4A", "KIF5B", "KLC1", "KMT2A", "KMT2B", "KPNA1", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3BP", "LIG1", "LIG3", "LIN9", "LIPA", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPCAT3", "LPGAT1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM4", "LSM7", "LSS", "LTA4H", "LUC7L", "LYN", "MACF1", "MAEA", "MAGT1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MEPCE", "MFAP1", "MFN2", "MGST1", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MOCS1", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPI", "MPP1", "MPST", "MRE11", "MRI1", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTR", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1C", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAM1", "NCAPG", "NCAPG2", "NCBP1", "NCBP2", "NCDN", "NCKAP1", "NCL", "NCOR1", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NFATC2IP", "NIPBL", "NKRF", "NME1", "NME6", "NONO", "NOP2", "NPC1", "NPC2", "NR2F2", "NSD1", "NSDHL", "NSF", "NT5C3A", "NTHL1", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCLN", "OGDH", "OGT", "OPA1", "ORC2", "ORC3", "ORC6", "OXCT1", "P3H1", "P4HA1", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELO", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGRMC2", "PGS1", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PIAS1", "PIGT", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PKN2", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMAIP1", "PMPCA", "PMVK", "PNP", "PNPLA8", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB21", "RAB2A", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RBBP7", "RBM14", "RBM17", "RBM39", "RBM4", "RBM5", "RBMX", "RBPJ", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RIF1", "RIPK1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPS1", "RP2", "RPA1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP38", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RTCB", "RTF1", "RTN3", "RTN4", "RUVBL1", "S100A10", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARS", "SC5D", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SDHC", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEL1L", "SEPT11", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SFPQ", "SFSWAP", "SGPL1", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIN3A", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMYD3", "SNAP23", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SPEN", "SPNS1", "SPOP", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRPK2", "SRRM1", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSR4", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STIP1", "STMN1", "STOM", "STRAP", "STRN", "STUB1", "STX3", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SUZ12", "SYNE2", "TAB1", "TACO1", "TALDO1", "TAP1", "TARDBP", "TBC1D4", "TBCA", "TBL1XR1", "TBL2", "TCF20", "TCP1", "TECR", "TELO2", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMELESS", "TIMMDC1", "TJP1", "TK1", "TKT", "TLE3", "TLN1", "TM7SF2", "TMED10", "TMEM126B", "TMEM165", "TMEM43", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNPO1", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP3A", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRIP4", "TRRAP", "TSG101", "TSPYL1", "TTC19", "TTC26", "TTF1", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TXNDC15", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBAP2L", "UBE2J1", "UBE2L3", "UBE2N", "UBE3A", "UBIAD1", "UBR5", "UBTF", "UCHL5", "UFD1", "UGGT1", "UHRF1", "UMPS", "UNC119", "UPF1", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP10", "USP5", "USP7", "USP9X", "UTRN", "VANGL1", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS16", "VPS33A", "VPS4A", "WAPL", "WARS", "WDHD1", "WDR1", "WDR26", "WDR5", "WDR74", "WFS1", "WIPI2", "XAB2", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YES1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZEB2", "ZFR", "ZMPSTE24", "ZNF281", "ZNF318", "ZYX"], "leading_proteins": ["ABCB1", "ACAT2", "ACOT8", "ACOX3", "ACP6", "ADAR", "ADI1", "AIFM1", "AKAP1", "AKAP8", "AKT2", "ANXA6", "APOB", "ASAH1", "ASNA1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5B", "ATP5L", "ATP6", "ATP6AP2", "ATP7B", "BAG3", "BAX", "BCL2L13", "BRCA1", "CCNB1", "CDC37", "CDK4", "CDKAL1", "CEP44", "CERS2", "CETN2", "CHST14", "CLCN7", "CLUH", "COA3", "COLEC12", "COX15", "COX2", "COX4I1", "COX5A", "COX6C", "COX7A2", "CPT2", "CRTAP", "CTNNA1", "CTNNB1", "CTTN", "CYB5B", "CYP20A1", "CYP51A1", "DDX17", "DDX3X", "DHCR24", "DHFR", "DNAAF2", "DYNLL2", "ECE1", "ECSIT", "EI24", "EIF3F", "EIF3H", "EIF4E", "EIF5", "ELP3", "EMD", "EPHX1", "EXO1", "FANCD2", "FDFT1", "FECH", "FLAD1", "FOXRED1", "GLA", "GLB1", "GNA13", "GNAI1", "GNAI2", "GNG5", "GPAM", "GRB2", "GSR", "GSTO1", "HLA-A", "HLA-C", "HMOX1", "HNRNPF", "HNRNPH1", "HTRA2", "ICMT", "IGF2BP1", "ILK", "KDSR", "KEAP1", "KLC1", "LMAN1", "LMNB1", "LTA4H", "MAVS", "MBNL1", "MCL1", "MED1", "MIF", "MPP1", "MSMO1", "MTAP", "MTOR", "NAGLU", "NAMPT", "NAP1L1", "NCBP1", "NCBP2", "ND1", "NDUFA11", "NDUFA13", "NDUFA7", "NDUFAF1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFS6", "NEFL", "NEFM", "NPC1", "NUBPL", "P3H1", "PDK1", "PFDN1", "PIN1", "PIP4K2C", "PMAIP1", "PMPCA", "POLR1C", "POLR2E", "POLR2L", "POLR3A", "PON2", "POR", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMD11", "PSMD7", "PSME2", "PTGES2", "RAC1", "RBPJ", "RPN1", "RRM2", "RTN3", "RTN4", "SAP18", "SCARB1", "SCARB2", "SCO1", "SCO2", "SEL1L", "SETDB1", "SGPL1", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A13", "SLC25A20", "SLIT2", "SNW1", "SQLE", "STAT3", "STOM", "TAP1", "TFRC", "TIGAR", "TIMMDC1", "TM7SF2", "TMOD1", "TPM4", "TRIM25", "TTC19", "TUBB", "TUBB2B", "TUBB6", "TXNDC15", "UBE2N", "UBE3A", "UNC119", "UQCR10", "UQCRC2", "UQCRQ", "VDAC1", "VDAC2", "VDAC3", "VIM", "YBX1", "ZEB2", "ZMPSTE24"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json b/opencell_localization/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..b8835e9dbf12618fab08e092cb679aa465a711c1 --- /dev/null +++ b/opencell_localization/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "vesicles"} \ No newline at end of file diff --git a/opencell_localization/advanced/plot_0.png b/opencell_localization/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ea70d1df3788972607278392edcceee82ab2e844 --- /dev/null +++ b/opencell_localization/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8d18f59ab9ab9283d6a5f8d549338fac36b32ac3622fc592c9c95a783f4275d7 +size 202648 diff --git a/opencell_localization/basic/idx2term.json b/opencell_localization/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..155ecd4ec29e506029d54bd1e2b8eb7f05160dcf --- /dev/null +++ b/opencell_localization/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "vesicles", "1": "er", "2": "golgi"} \ No newline at end of file diff --git a/opencell_localization/basic/plot_0.png b/opencell_localization/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..595555290a6d91dfef16bf8efbf2bf480f34384f --- /dev/null +++ b/opencell_localization/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:44f8590c00df75e7fd80cf1a617d94fc23d99ec116a7fdc52614d5ef1ad19f2e +size 138269 diff --git a/opencell_localization/basic/plot_1.png b/opencell_localization/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..d00a567d6a1586b6c93e09e16700835548dfa0d0 --- /dev/null +++ b/opencell_localization/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7e374a0053b78307eb8d7cac382e5541681e33055a1e3d59d4ca20ca6ae6d02f +size 132118 diff --git a/opencell_localization/basic/plot_2.png b/opencell_localization/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..efe2147489132be5f08aaf052ca75d54411ca930 --- /dev/null +++ b/opencell_localization/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bd91efec5f0c60f83c267117dbf0ebbfa1b255c08923beb75203dc29bd839711 +size 136915 diff --git a/opencell_localization/consensus.joblib b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..b570797023bc285e3daf028aef547842a52617a3 --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:16f9be825b9e530e15fa79433a147cd32a61ba2b09e1bb7cc52197598f389eaa +size 69902 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4d376a56d907789643f595cf596640867d3852c8 --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +vesicles 44 160 2.505308366388915 0.0122344676043453 42.101941747572816 169.6626213592233 0.6789633151163722 0.6006686966705359 14.133870910307197 18.74575061031192 1.1351302778834993 0.3922666308151308 0.0755875895592779 0.497661437647895 0.4323059960297349 0.0043410813016268 2.400653255227324e-07 +mitochondria 3 11 2.19069739650204 0.0284736976284094 4.441747572815534 10.567961165048544 1.1937677940164793 0.2159787381789819 2.254231157409949 0.7391563798220593 1.4011905974754153 0.2980089661914649 0.0203954716413504 0.0017062060788896 0.0067896670197663 0.0382400085743442 0.0027630263410089 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..03b8cb506e76293b08a93f578b46fa1dac32959c --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 88.94117647058823 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..28d09dc5208e6c4e6320c91688d1d0a54c3f28f0 --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9706a5e17a4921a0f8a96e049aea9496e424db3a --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +vesicles 0.3895460385413229 2.505308366388915 0.0122344676043453 0.1888227743104352 0.2079859492738705 160 Q9Y3E0,O43752,O15173,P02786,Q9H2V7,P48449,O96005,Q5VW38,O95470,P31751,Q8IZA0,O00400,O15127,O43808,O15269,O00264,Q15363,O60749,O15400,Q93050,Q15758,Q15392,Q9Y6K0,Q969T9,P53985,Q14145,Q8IXU6,P50570,Q13277,O60476,P20020,Q9Y5K8,O14653,O95249,P30825,O14976,Q9UNK0,O75787,O60499,Q8IY95,Q06136,Q10713,Q9UI14,P41440 44 +mitochondria 0.7238949878585135 2.19069739650204 0.0284736976284094 0.3880336131151662 0.2420264298414803 11 P21796,P45880,Q15388 3 +er 0.4327796104262233 1.361509691200536 0.1733526730367163 0.9606952971017844 0.6357358757018008 98 Q9Y3E0,O15173,Q00765,Q9BRK0,P48449,O96005,O95470,Q9P0I2,O00400,Q9Y487,Q12981,Q13586,O75915,O15269,Q15363,Q9NPA0,Q9NQC3,Q15392,Q9Y6K0,Q16850,Q96A33,Q8NHH9,P51572,Q8TBX8,Q07065,Q9P2W9,Q9Y5M8,O60499,P46977,Q06136 30 +golgi 0.4281965848388507 1.211816946884713 0.2255824596872435 0.9870408034210348 0.6357358757018008 58 Q9Y3E0,O14976,Q5VW38,Q8IZA0,Q9Y487,Q9UI14,O14653,Q8IXU6 8 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..44c0394db4c9c57064ae8826ef6c79c959a8d0df --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AATF", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AHCY", "AHSA1", "AKAP12", "AKAP8L", "AKR1A1", "AKT2", "ALCAM", "ALDH9A1", "ALG2", "ANAPC16", "ANAPC2", "ANXA11", "AP2B1", "AP2S1", "APLP2", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8A", "ARL8B", "ARPC2", "ARPC3", "ATG3", "ATL2", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATXN10", "ATXN2L", "AURKB", "BAG4", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BLM", "BLVRA", "BMS1", "BNIP1", "BOP1", "BRD2", "BRD3", "BRD4", "BTF3", "BUB1B", "BUD23", "BYSL", "C19orf53", "C8orf33", "CAD", "CAMK2G", "CANX", "CAPRIN1", "CAPZB", "CBX1", "CCAR1", "CCDC22", "CCDC47", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKN2A", "CEPT1", "CETN2", "CHEK1", "CHMP2A", "CHMP6", "CHMP7", "CKAP2", "CKAP4", "CKAP5", "CKB", "CLASP1", "CLCN7", "CLNS1A", "CLPTM1", "CLTB", "CLTC", "CNN2", "COIL", "COL4A3BP", "COMMD1", "COPA", "COPB2", "COPG1", "COPG2", "COPZ1", "CORO1C", "CPSF6", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTCF", "CTNNB1", "CTNNBL1", "CTPS1", "CTTN", "CYB5R3", "CYP51A1", "DAD1", "DCTN2", "DDB1", "DDOST", "DDX21", "DDX39B", "DDX47", "DDX5", "DDX56", "DDX6", "DHCR24", "DHX37", "DHX9", "DIAPH1", "DKC1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB6", "DNAJC11", "DNAJC13", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DOCK7", "DRG1", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EBNA1BP2", "EDC3", "EDC4", "EDF1", "EEF1G", "EFTUD2", "EIF2AK2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3K", "EIF3M", "EIF4A1", "EIF4A3", "EIF5", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMG1", "ENO1", "EPS15", "ESD", "ESYT1", "EZR", "FAM120A", "FAM207A", "FARP1", "FASN", "FAU", "FBL", "FDPS", "FKBP5", "FKBP8", "FXR1", "G3BP1", "G3BP2", "G6PD", "GAK", 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sha256:96a6b4e6ef9fde6564a696bccc1990ab7e5964275bf730975d75eb575c10c6f6 +size 81274 diff --git a/panther_protein_class/df_merge.tsv b/panther_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..76a90786a331b45aa97ca89e4e343f52c3d4572b --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,15 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +membrane trafficking regulatory protein 4 16 3.0477041896018853 0.0023059680175494 4.949029126213592 18.78640776699029 1.0645815505395402 0.2320552342124929 2.3097144002673033 2.893415643517755 1.4460865220385617 0.2677048300346334 0.0021262505871442 0.0020640692536444 0.0017009652209114 0.008923404115777 0.1132481709467278 +SNARE protein 9 13 2.535826119470756 0.0112182420429136 4.660194174757281 11.12378640776699 0.9288896561072936 0.3201954718639376 2.5506648592929815 2.745113440103806 1.1546709449924732 0.3042666981599379 0.3968926535471839 1.0 1.0 0.0049571663496986 5.065093383128868e-05 +metalloprotease 8 25 2.527788577088092 0.0114783450222646 8.58495145631068 26.398058252427184 1.4262736372921438 0.246779453311036 3.321022586051017 1.6463540525991265 1.1083706824215755 0.2918245458017476 0.0138782692041512 1.0 0.0154029461510805 4.204252026569053e-05 0.0002308677663279 +ATP synthase 3 21 2.4795336779402533 0.0131554306021732 6.381067961165049 20.483009708737864 0.8573640874951715 0.3249378356888472 2.8850015270213047 1.3977105655851854 1.2517106680730556 0.3017789026221172 0.0018757503369794 1.3464861962563283e-05 0.0002151657881401 0.0063239101987386 0.0005790030159305 +primary active transporter 16 26 2.431550250893131 0.0150343626733626 8.614077669902912 23.45631067961165 1.2392440710771837 0.271771563990288 4.792195908457348 3.1431129799052804 1.4794913205770832 0.3014776193450941 0.004233881602233 0.2588687133858448 0.0222198796395938 0.0168986737095617 0.0007324740008612 +transporter 21 56 2.3977584760818926 0.0164957380476393 16.281553398058254 57.34708737864078 1.7781248355514696 0.2510912048406951 6.627271511266295 3.5084386843827997 1.4364723564792363 0.3433005081320681 0.0001851940138345 0.0023437820755387 0.0009447418031535 0.0005338046281504 3.174131100404598e-06 +acyltransferase 5 18 2.33736266656296 0.0194203346221777 5.550970873786408 17.609223300970875 0.8395368249042097 0.3495065414698917 3.0409541216574527 2.8086572783837886 1.152491475155923 0.3107783941454108 0.0355040413058726 0.1835089509173778 0.0625314301217693 0.0182997950486615 0.0150707717640174 +oxidase 7 14 2.288540213053534 0.0221060810782547 5.111650485436893 13.890776699029129 1.1786899361665428 0.2351652471103072 2.6295852591466065 1.831549924215542 1.2715889014379809 0.2754701040210626 0.4375879146969009 0.1471951297158956 0.2756599666896902 0.0010916803236277 0.0001380057592112 +protein modifying enzyme 8 24 2.2642209073347352 0.0235605313040487 6.487864077669903 24.82281553398058 0.9737051724681342 0.3238157719208961 2.575528657386725 2.871041189126622 1.1448244681235864 0.2930923238696635 0.0176600324030677 0.0315268496209905 0.0023751027082345 0.0129296559640097 0.0065824357934952 +oxygenase 5 7 2.204645733695167 0.027478963870573 3.138349514563106 6.771844660194175 1.5409868347565758 0.1477866581414416 1.2914149665013366 1.041089559555361 1.2379399582807478 0.2357869798067575 0.0078387944068705 0.1093006244161378 0.0015498580582828 0.0195244436529747 0.0008083265510004 +mitochondrial carrier protein 5 9 2.199898060289342 0.0278141283775175 3.2936893203883497 7.065533980582524 1.4583792806536486 0.1840967072966826 2.0141872967986307 1.116111686789906 1.1161599809390137 0.2507152229846449 0.0203954716413504 0.0607401038440192 0.1191939669275513 0.0382400085743442 0.0002457979454447 +transmembrane signal receptor 6 7 2.188058798563906 0.0286653195920656 3.266990291262136 7.169902912621359 1.6693846681257831 0.1085289610325799 1.5770125590990791 1.7927217985188668 1.0928815816574815 0.16461969248918 0.0746190711333647 0.0720814043883259 0.0600500471997379 0.183699096822524 0.2885640587878388 +ion channel 1 5 1.979184534002176 0.0477952335710774 2.0072815533980584 5.492718446601942 0.2992882974166039 0.3902010231102108 1.227692360641773 1.2742579749591922 1.1645136438376027 0.2881631781964495 0.0785007730839361 0.1221118561195742 0.2318581098993339 0.1383652025719425 0.3798345415961738 +ATP-binding cassette (ABC) transporter 6 11 1.9619115696864755 0.0497727805906089 2.686893203883495 7.684466019417476 0.6951371488068213 0.3450534093319853 1.8332217537175712 2.163791049328932 1.0940500371142112 0.2754733493972692 0.0591475015489903 1.0 0.2012104780589677 0.0173886328284286 0.0042957165481444 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..24f1c7409fc9dad97f3a5e671328abe9cd3844ba --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 157, + "title": "Average number of proteins per term", + "value": 13.299363057324841 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..04a6a6acb004d22d937534e63d2a853e2bc79aef --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..cc9104ca3e36f47cde85f294c6de46b49126bfae --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,46 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +membrane trafficking regulatory protein 0.7707263809885965 3.0477041896018853 0.0023059680175494 0.3040343994897455 0.1946843902492452 16 O43731,Q14108,P24390,Q8WTV0 4 +SNARE protein 0.7457374566363582 2.535826119470756 0.0112182420429136 0.8298742918260602 0.1946843902492452 13 O43752,O95249,O15400,Q13277,Q9P2W9,O60499,Q13190,Q9UNK0,O14653 9 +metalloprotease 0.6256743918996344 2.5277885770880917 0.0114783450222646 0.8367581709055965 0.1946843902492452 25 O75844,Q9UIQ6,P22695,Q9NZ08,P55786,Q96TA2,P42892,Q7Z2K6 8 +ATP synthase 0.6450704994870127 2.4795336779402533 0.0131554306021732 0.8749583719655408 0.1946843902492452 21 Q9Y487,P00846,Q93050 3 +primary active transporter 0.6042289063897067 2.431550250893131 0.0150343626733626 0.9072936518226076 0.1946843902492452 26 Q04656,Q8N4H5,P16615,P05023,P98194,Q9GZP9,Q96NB2,Q15758,O75381,Q9NS69,Q6P4A7,P35670,Q15388,P20020,Q6NTF9,P23634 16 +transporter 0.5593483683792136 2.3977584760818926 0.0164957380476393 0.9265704848306984 0.1946843902492452 56 O43615,O43681,Q9H2V7,Q99595,O60830,Q9HD45,Q567V2,Q9Y584,Q9UJZ1,P53985,P62072,O43772,Q8N1F7,Q9Y619,Q96EE3,Q9UI26,Q9H2D1,Q9NR77,Q7Z3B4,P41440,Q15070 21 +acyltransferase 0.6384739762490319 2.3373626665629597 0.0194203346221777 0.9539941972196768 0.1946843902492452 18 Q9BWD1,Q9HCL2,P23786,Q8NCC3,Q99943 5 +oxidase 0.6798225829889301 2.288540213053534 0.0221060810782547 0.9700908523501576 0.1946843902492452 14 P14406,O43819,Q15800,P50336,O75880,P20674,P13073 7 +protein modifying enzyme 0.594049323595382 2.2642209073347352 0.0235605313040487 0.9763235742900804 0.1946843902492452 24 P50897,Q9UMR5,O15294,O60476,O60725,O75718,Q86YN1,Q15102 8 +oxygenase 0.8301840856348845 2.204645733695167 0.027478963870573 0.987406581219697 0.2045661443615593 7 P30519,P09601,Q6UW02,Q16850,Q14534 5 +mitochondrial carrier protein 0.7700078379315834 2.199898060289342 0.0278141283775175 0.9880699863187232 0.2045661443615593 9 Q86VD7,Q70HW3,Q9BSK2,P16260,Q9Y6C9 5 +transmembrane signal receptor 0.8262698155936705 2.188058798563906 0.0286653195920656 0.9896027971766842 0.2045661443615593 7 Q99720,O15173,Q8WUJ1,O75787,Q15375,Q9UMX5 6 +ion channel 0.8377839043825637 1.979184534002176 0.0477952335710774 0.9995422112458118 0.3125730621090243 5 Q9C0H2 1 +ATP-binding cassette (ABC) transporter 0.6787120517345276 1.9619115696864755 0.0497727805906089 0.9996696971878546 0.3125730621090243 11 Q03518,O14678,Q8NC96,P08183,P33527,O75027 6 +esterase 0.7035988421928335 1.888198755046587 0.0589992729034782 0.9999286122715476 0.3525274915898375 9 Q9NUJ1,Q969T7,Q8IY17 3 +heterotrimeric G-protein 0.7514531396334174 1.7812413034523935 0.074873038810046 0.999995061329542 0.4053471411440423 6 P63218,Q14344,P04899,Q8NHH9 4 +serine protease 0.5345220796961067 1.6716174674535875 0.0945997781086438 0.9999998325158684 0.4791021020340994 18 Q9H3G5,P42785,Q9HB40,O14773,Q16740 5 +secondary carrier transporter 0.5143408035061217 1.5800338693430471 0.1140991102783215 0.999999994511336 0.4810626408616257 20 Q9Y6M7,O95202,Q9BQT8,Q8TB61,Q9UBX3,O75746,Q96H78,Q9UJS0 8 +amino acid transporter 0.8005817711700072 1.5609442859545712 0.1185368969522384 0.99999999750512 0.4810626408616257 4 O75915,P30825,O14925 3 +G-protein coupled receptor 0.9544426494345746 1.5441015635198578 0.1225637301558282 0.999999998784244 0.4810626408616257 3 Q9NPR9,Q5VW38 2 +glycosidase 0.7528352051247356 1.3706099487330057 0.1704965799609339 0.9999999999998204 0.5553123903157732 4 Q9BTY2 1 +voltage-gated ion channel 0.8920154241425617 1.3166328606722335 0.1879617184424042 0.9999999999999936 0.5884493815481581 3 P21796 1 +tubulin 0.8436187399030685 1.1408653522521912 0.2539259597079577 1.0 0.6335934805416971 3 P07437,Q9BVA1 2 +lyase 0.4940751123296296 1.1194750863553071 0.2629375136456926 1.0 0.6335934805416971 13 P22830,Q9UHG3,P35914,Q8NBM8 4 +oxidoreductase 0.4125550831049601 1.1153696740094006 0.2646920394468339 1.0 0.6335934805416971 48 O43676,O96000,O95182,O14949,O15254,O95168,P00403,O95831,Q8N4Q0,Q8N0U8,O43169 11 +reductase 0.3958792886868445 1.003363346923012 0.3156855820718598 1.0 0.6608351518037598 30 Q9H7Z7,O76062,Q9UDW1,Q15392 4 +viral or transposable element protein 0.7687338501292018 0.9160471425702276 0.3596421693965812 1.0 0.7002068179732764 2 Q9H2J4 1 +membrane traffic protein 0.3954966511789218 0.8968415512112213 0.3698034724003147 1.0 0.7002068179732764 59 A6NIH7,Q9Y2D4,Q5JRA6,P43307,Q00765,P50570,Q6NUK4,Q9BRK0,O14976,Q9NX40,Q8N2H4,P51572,Q96PC5,Q13432,O00203,O60313,Q9UI14 17 +histone modifying enzyme 0.4271308209674294 0.8486466838346619 0.3960779218133101 1.0 0.7002068179732764 15 Q9H0E3,Q15047,Q8WUB8,Q9H7B4,Q9H9T3 5 +major histocompatibility complex protein 0.7418001997693924 0.7812265093277032 0.4346692848435463 1.0 0.703536883715843 3 P10321 1 +galactosidase 0.732901976341042 0.7510358065167291 0.4526311068898394 1.0 0.710305429696546 3 P16278 1 +calmodulin-related 0.4007293354278972 0.6215386829738285 0.5342452508743196 1.0 0.7623382184340264 14 Q14257,P80303,Q9BRK5,P41208 4 +hydrolase 0.3779158285753771 0.6143592218611195 0.5389779760902988 1.0 0.7623382184340264 19 P07099,O60502 2 +kinase 0.3661392039869732 0.5270710144512399 0.5981442744357472 1.0 0.7907401157446677 16 Q8TBX8,Q53H12,Q8WVC6,Q9BRR6 4 +nucleic acid metabolism protein 0.5239172592113783 0.4896745917817502 0.6243641840958816 1.0 0.7907401157446677 4 Q96FV9,Q9NYF8,Q9Y2W1 3 +DNA glycosylase 0.6434108527131811 0.4792967919884275 0.6317275040350181 1.0 0.7934497450679827 2 P78549 1 +nucleotide phosphatase 0.4234539407394261 0.3618031655713692 0.717499126403619 1.0 0.8363204762126776 6 Q5TFE4,P49902,Q9BX68 3 +translation initiation factor 0.3146388869476402 0.3118945539137935 0.7551206615530663 1.0 0.8649194626461998 39 O75153,P55010 2 +kinase inhibitor 0.5822294022617037 0.3051555554630352 0.7602476805425196 1.0 0.8649194626461998 3 Q96P16,Q5VT52 2 +Hsp90 family chaperone 0.4065934065934085 0.1600420203286062 0.8728479733724555 1.0 0.9450836677205208 4 Q12931,P08238,P07900 3 +guanyl-nucleotide exchange factor 0.3553291765737722 0.1403538594143975 0.8883804117639491 1.0 0.9553131825132876 6 Q9Y4G8,Q14C86 2 +non-motor microtubule binding protein 0.3147487844408576 0.1293584123239191 0.8970740532871044 1.0 0.9580994990889482 13 Q96CW5,Q14008,Q15555,Q9BSJ2,Q9BZD4,Q8WWK9,O43663,Q7Z460,P60520,O94901,Q15691,Q9ULW0 12 +protease 0.2837555609314356 0.0789237465632692 0.937093275127452 1.0 0.9940786769933108 38 Q99436,P28074,P28072,Q9BT78,P49721,P28070,P20618,O75976 8 +mRNA capping factor 0.27745478036175 0.0450519384685738 0.964065910039612 1.0 1.0 2 O75319 1 +glucosidase 0.3667205169628403 0.029923829316757 0.9761278013104868 1.0 1.0 3 P10253,Q13724 2 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..437f2f23fc1171f6a74f60e188c53e4814f1cb20 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "C4 zinc finger nuclear receptor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "storage protein", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "zinc finger transcription factor"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGPAT1", "AGPAT5", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC7", "ANGEL1", "ANKFY1", "ANLN", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APLP2", "APOB", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARID3B", "ARL1", "ARL6IP5", "ARPC1A", "ARPC3", "ARPC4", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD5", "ATG3", "ATL2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BAP18", "BCAP29", "BCAP31", "BCAS2", "BCAT2", "BCKDHA", "BCKDHB", "BCLAF1", "BLM", "BLMH", "BLVRA", "BOP1", "BPHL", "BRCA1", "BRD1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX8", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKN2AIP", "CEBPZ", "CENPC", "CEPT1", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHDH", "CHEK1", "CHERP", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNP", "COA1", "COA3", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSE1L", "CSGALNACT2", "CSNK1A1", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBT", "DCAF13", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DDT", "DECR1", "DECR2", "DEK", "DENR", "DERL1", "DERL2", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC25", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERH", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESCO2", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FAM3C", "FAM98A", "FAM98B", "FARS2", "FARSA", "FARSB", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDE1", "GDI2", "GDPD1", "GFM2", "GGH", "GID8", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLMN", "GLO1", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLT1B", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HM13", "HMGA1", "HMGCL", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATIP2", "HTRA2", "HUWE1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPAD1", "IMPDH2", "ING5", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "ISCU", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LENG8", "LETM1", "LETMD1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A2", "MAPK1", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "METTL16", "METTL7B", "MFAP1", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKRN2", "MMAB", "MMS19", "MOGS", "MON2", "MORF4L1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKIPSD", "NCOA5", "NCOR1", "ND1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NENF", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NKTR", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA1", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN3", "NSUN4", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC6", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPN1", "PAFAH1B3", "PAFAH2", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PARN", "PARP1", "PARP2", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHC2", "PHF10", "PHF3", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PICALM", "PIGL", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2B", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN9", "PUF60", "PURA", "PUS1", "PWP1", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABAC1", "RAC1", "RACGAP1", "RAD23B", "RAD51C", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM26", "RBM27", "RBM34", "RBM4", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIPK1", "RNASEH2A", "RNF2", "RNMT", "RNPS1", "RP2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", 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"SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35A3", "SLC35B2", "SLC37A4", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPOP", "SPOUT1", "SPR", "SPTLC1", "SPTLC2", "SQLE", 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0000000000000000000000000000000000000000..84f29f717fcd3e3dd11beec7f457f12dc1c6d93e --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,13 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transporter 74 201 4.046774258575812 5.192827547340073e-05 57.59466019417476 188.27912621359224 1.4971900036635353 0.4160578104205245 21.77919356765414 18.57070590158326 1.926868489654782 0.421013047757716 0.0002807512321432 0.0284981099050074 0.0075526899783523 7.700846869713773e-07 4.8118559923156423e-14 +SLC25 family of mitochondrial transporters 15 25 3.3156711128906715 0.0009142335245009 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.0004033290427702 0.1635258499471353 0.0498890213657128 2.4880325513906888e-05 7.341638285000007e-10 +Receptor 9 26 2.8013747264691946 0.0050885393381385 8.25242718446602 27.344660194174757 1.739519175745715 0.1905542238199536 2.855648283399814 4.245230977176689 1.1861053756197322 0.2707159726336181 0.002352789590523 0.0142331659478869 0.0195561525514714 0.004144931190839 0.0328461598740068 +SLC superfamily of solute carriers 29 55 2.5894872662741246 0.0096118977679442 18.888349514563107 44.33009708737864 2.1618907004737498 0.1690913715307362 9.633686860107934 5.825351940723624 1.7350998035598977 0.2760301582542676 0.013551735476916 0.587145575543033 0.2597010673684694 3.483357558991818e-05 1.8630736326989034e-07 +SNARE protein 7 12 2.5176683384409912 0.0118134502606692 4.555825242718447 10.6626213592233 0.9494792984446184 0.3117420251981136 2.5225757464631977 2.583604188764985 1.1633177546874711 0.3031193116521645 0.3754602418326228 1.0 1.0 0.0038040834633598 2.855045826118248e-05 +F-type and V-type ATPases 2 17 2.490890722649699 0.0127423304201246 4.995145631067961 15.616504854368932 0.6819760311565471 0.3553057475304781 2.5561606009064737 1.187932616128487 1.149561543758102 0.2999604229905949 0.0069459336161985 0.000172657384578 0.0013656945298514 0.0173886328284286 0.0042957165481444 +Metalloprotease 12 35 2.315053233093359 0.0206100189782409 10.080097087378642 37.81310679611651 1.0846602244748076 0.3802793741361127 4.2814674000125414 2.184793664748831 0.9789887795730944 0.3416347995760264 0.0372032513718843 1.0 0.0338721796728873 0.0003656395100037 0.0001840815286022 +Mitochondrial nucleotide transporter subfamily 5 11 2.304391450175455 0.0212006795168755 4.216019417475728 9.065533980582524 1.5870110662923598 0.1668197633609344 2.720728714423222 1.1029864386277723 1.1616247375257451 0.2431804664231326 0.0268439946301445 0.0697581245313758 0.1362380906066266 0.0498779046475234 0.0005289198821125 +Mitochondrial amino acid transporter subfamily 5 7 2.2530403310837497 0.0242566061284834 1.75 5.106796116504855 1.5314439851709 0.1644824524943633 1.357512359363716 0.7195281808878056 0.8276270779181836 0.2049815877367878 0.0077477002373928 1.0 0.075113296023457 0.0007187465088185 3.274702614006158e-07 +Esterase 4 12 2.208866521685283 0.0271839264099549 2.4199029126213594 10.856796116504857 0.6548503739556798 0.3454832165784889 1.4749994208625692 1.2546524785480109 1.099568757577031 0.2732488393636652 0.0001327727267659 0.0026008925831016 0.000453663444764 0.0004862334359502 0.0007388687073799 +Ion channel 2 8 2.18682274940563 0.0287554660562805 2.9611650485436893 8.271844660194175 0.2358363301857469 0.3871382019519256 1.7759030526384678 1.9242659665051836 1.1979225459677625 0.2963208074862355 0.0446798083571155 0.1991580424676108 0.3622612502953293 0.0998367022916053 0.3878167330330442 +Extracellular structure 4 9 2.0839178165206533 0.0371676434342393 2.842233009708738 8.092233009708737 0.8560017356043709 0.3472532488838395 1.4285109580808126 1.0866524100509705 0.962827743376652 0.290186194394739 0.3644617429926986 1.0 0.2243071172363204 0.4718643991127431 0.0351238878380088 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2e879650a2f25675c590effd4622749514babdc2 --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 1952, + "title": "Average number of proteins per term", + "value": 3.1357581967213113 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7a9e1260d6a38ebaf35ee98ca01b9687a6f0ba3d --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f754a5d4a078220bf230a4ecbf8f735868c95f1c --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,63 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter 0.5075537960280028 4.0467742585758115 5.192827547340073e-05 0.0963983114009827 0.0622725094974948 201 Q03518,Q9Y2D4,P00846,O43752,P16615,Q00765,Q9H2V7,Q9BRK0,O14678,Q96NB2,Q9NRW7,P35670,Q8N2H4,P57740,Q9HD45,Q70HW3,O00400,Q9NZJ7,Q9Y584,Q9Y487,P33527,O43808,O43760,O75027,Q9UJS0,Q15363,O60749,Q86VD7,P24390,O15400,Q93050,Q15758,Q9BQT8,Q15388,Q8TB61,Q9UBX3,P53985,O43731,Q96H78,P16260,Q8IXU6,O43772,Q8N1F7,Q9Y619,Q96EE3,P98194,Q13277,P51572,O95563,Q9Y3B3,P08183,O00203,P20020,O75746,Q9Y5K8,O14653,Q9Y6C9,Q9Y6M7,O95249,Q9BVK6,P30825,Q9UNK0,O95202,Q9H2D1,Q9HC07,Q9P2W9,P06576,O60499,Q9BSK2,Q9UI14,Q8TBP6,Q7Z3B4,P41440,Q15070 74 +SLC25 family of mitochondrial transporters 0.7470280292359393 3.3156711128906715 0.0009142335245009 0.8322700612679061 0.0622725094974948 25 O43772,Q86VD7,Q9Y619,Q9H2D1,Q8TBP6,Q9BQT8,Q70HW3,Q9BSK2,Q9NZJ7,Q9UBX3,O75746,Q96H78,P16260,Q9Y6C9,Q9UJS0 15 +Receptor 0.6581475908813743 2.8013747264691946 0.0050885393381385 0.9999526615001202 0.0622725094974948 26 A6NIH7,Q14108,Q8WTV0,O75381,Q13432,Q567V2,Q9NR77,Q13641,Q9UQB8 9 +SLC superfamily of solute carriers 0.5821154135225799 2.5894872662741246 0.0096118977679442 0.9999999935111318 0.0626687159558687 55 Q9H2V7,Q96NB2,Q70HW3,O00400,Q9NZJ7,O43808,Q9UJS0,Q86VD7,Q15758,Q9BQT8,Q8TB61,Q9UBX3,P53985,Q96H78,P16260,Q8IXU6,O43772,Q9Y619,O95563,O75746,Q9Y6C9,Q9Y6M7,P30825,O95202,Q9H2D1,Q9HC07,Q9BSK2,Q8TBP6,P41440 29 +SNARE protein 0.76503919509126 2.5176683384409912 0.0118134502606692 0.9999999999157426 0.0671776321526954 12 O43752,O95249,Q13277,Q9P2W9,O60499,Q9UNK0,O14653 7 +F-type and V-type ATPases 0.6684088181710471 2.490890722649699 0.0127423304201246 0.999999999986561 0.0690917471668979 17 Q9Y487,P00846 2 +Metalloprotease 0.5407512225080735 2.315053233093359 0.0206100189782409 1.0 0.0853637200451224 35 O75844,O00303,Q9UIQ6,P22695,Q9NZ08,P51665,P55786,O43847,Q96TA2,Q10713,P42892,Q7Z2K6 12 +Mitochondrial nucleotide transporter subfamily 0.7468004580750478 2.304391450175455 0.0212006795168755 1.0 0.0863577950610521 11 Q86VD7,Q9H2D1,Q70HW3,Q9BSK2,P16260 5 +Mitochondrial amino acid transporter subfamily 0.8416485885009808 2.2530403310837497 0.0242566061284834 1.0 0.0919314995426978 7 O43772,Q9Y619,Q96H78,Q8TBP6,Q9UJS0 5 +Esterase 0.7046431656164802 2.208866521685283 0.0271839264099549 1.0 0.0971850262861392 12 Q9UMR5,P50897,Q969T7,Q8IY17 4 +Ion channel 0.7890699150588883 2.18682274940563 0.0287554660562805 1.0 0.0996295761450846 8 Q9C0H2,P0CG08 2 +Extracellular structure 0.7450208746215061 2.0839178165206533 0.0371676434342393 1.0 0.1147962657968912 9 P55081,Q5KU26,O75718,Q32P28 4 +P-type ATPases 0.7092076936829891 1.9149496924729523 0.0554989196372757 1.0 0.1454368570037902 9 Q04656,P16615,P98194,P35670,P20020,P23634 6 +Membrane trafficking regulatory protein 0.5717699614761053 1.8934041331458225 0.0583041462083337 1.0 0.149874507547653 17 P24390,Q96EE3,O43731,O43760,O60749 5 +Reductase 0.57303251691427 1.881896641072941 0.0598500506000743 1.0 0.152516055837265 16 Q9H7Z7,O76062,Q9UDW1,Q15392 4 +Oxidase 0.5612114849556282 1.871168076703564 0.0613217880540193 1.0 0.1545664938896039 19 O15254,P14406,Q15800,P20674,O43169 5 +Phosphatase 0.5214057975241135 1.8321990891308169 0.0669217645383046 1.0 0.1616723816568944 26 O43681,Q9NPH0,P11117,Q86YN1,P49902 5 +Signaling 0.5515950150530322 1.784167938807847 0.0743963803389795 1.0 0.1743358156322786 18 O15173,Q07812,P43490,Q5JRA6,Q8WUJ1,Q96PC5,Q07820,Q99627,O00264 9 +Heterotrimeric G-protein 0.7514531396334174 1.7812413034523935 0.074873038810046 1.0 0.1748231719583849 6 P63218,Q14344,P04899,Q8NHH9 4 +ATP-binding cassette transporter family 0.6967838469280864 1.7662145597284151 0.0773598592915438 1.0 0.1787174696377546 8 Q03518,P33527,P08183 3 +ABCB subfamily 0.7170442085334139 1.6316083595917583 0.102762016061491 1.0 0.2140783941857316 6 Q03518,P08183,O75027 3 +Ca2+-ATPases 0.8154492566257279 1.6198637097767807 0.1052615569365702 1.0 0.2169699674130782 4 P98194,P20020,P16615 3 +V-type ATPase 0.654779949363695 1.568550198787026 0.1167527844008986 1.0 0.2321240777782375 8 Q9Y487 1 +Mitochondrial di- and tri-carboxylic acid transporter subfamily 0.8009095714959305 1.562245463799184 0.1182301740811766 1.0 0.2333521737173476 4 Q9BQT8 1 +SLC35 family of nucleotide sugar transporters 0.8845692208279112 1.28951438679859 0.1972193180009833 1.0 0.3303884904090178 3 Q8IXU6 1 +Lipase 0.7154587499549676 1.221000775741337 0.2220857260771624 1.0 0.3553371617234599 4 Q8NCC3 1 +Oxygenase 0.6538151888694061 1.2063182763780445 0.2276947933157225 1.0 0.3613497858148701 5 Q16850 1 +Miscellaneous SLC25 mitochondrial transporters 0.8278423772609855 1.1445292349606195 0.2524042207984562 1.0 0.3879472748020367 2 Q9Y6C9 1 +Tubulin 0.8436187399030685 1.1408653522521912 0.2539259597079577 1.0 0.3896725419417716 3 P07437,Q9BVA1 2 +CDK family 0.6364828740978897 1.1321904264340503 0.2575543841459426 1.0 0.3929117057628316 5 P50750,P11802 2 +Hydrolase 0.4147874387399942 1.0989496442531372 0.2717900308619021 1.0 0.4037550534569505 89 O43681,P50897,P16278,P06865,Q6PIU2,Q9NPH0,Q9UMR5,Q8NCC3,P11117,Q969T7,Q86YN1,Q5T9A4,P49902,Q8TF05,Q8IY17 15 +Nucleotide phosphatase 0.5413017127477991 1.0211776463263391 0.3071702810398586 1.0 0.4363874735005852 8 O43681,Q9BX68,Q5TFE4,P49902,Q9H857 5 +Calcium-binding protein 0.421894402903652 0.9648634469246063 0.3346132119590554 1.0 0.4599753448901946 22 Q8N163,P43307,Q02818,P14649,P80303,Q14257,Q9BRK5,P41208 8 +Cu+-ATPases 0.7729328165374701 0.931985043672298 0.3513442548847139 1.0 0.4731182697185965 2 P35670 1 +Translation initiation factor 0.4241258851807593 0.9219783114200446 0.3565398887767006 1.0 0.4786560267483629 18 P55010 1 +Growth factor 0.5688982350961542 0.8456310528045214 0.3977585968401955 1.0 0.5124916046416249 5 Q96PC5 1 +DNA helicase 0.4426138520067318 0.8138074391710446 0.4157552727166353 1.0 0.5274397242612285 13 P12956,P33991,Q96S55 3 +Oxidoreductase 0.3601238446027431 0.7773557532699624 0.4369489097626178 1.0 0.5426296713395277 120 Q9H7Z7,Q9UDW1,O15254,P14406,Q15392,O43819,O95831,Q15800,P03886,Q8N4Q0,Q16850,Q8N0U8,O76062,O43169,Q9P0J0,P30837,Q13423,P20674 18 +Calmodulin 0.4015505729453807 0.761167789649769 0.4465568545003644 1.0 0.5482257735752901 17 Q8N163,Q02818,P14649,P80303,Q14257,Q9BRK5,P41208 7 +Intracellular calcium-sensing protein 0.4015505729453807 0.761167789649769 0.4465568545003644 1.0 0.5482257735752901 17 Q8N163,Q02818,P14649,P80303,Q14257,Q9BRK5,P41208 7 +Kinase inhibitor 0.5156805690268367 0.6280997924869032 0.5299385690220157 1.0 0.6150059968674046 5 Q9UBW7,Q96P16,Q5VT52,Q9NQG5 4 +SLC12 family of cation-coupled chloride transporters 0.6873385012919848 0.6216039295189206 0.5342023365230297 1.0 0.6177027051676944 2 Q9BXP2 1 +Translation factor 0.3619781195507867 0.5448748911005636 0.585839566429978 1.0 0.6489275907001173 23 P55010 1 +Phosphatase inhibitor 0.538309531864082 0.5393549384167968 0.5896419675807485 1.0 0.6504877708794448 4 P55209 1 +G-protein 0.3366050008160557 0.5032409429347847 0.614794882173288 1.0 0.6689406967682598 30 P62070,P04899,P50570,Q9UI26,Q8NHH9,P63218,Q14344,O60313,Q96P70,P63096 10 +Guanyl-nucleotide exchange factor 0.647960043084328 0.4810275494446774 0.6304969188149638 1.0 0.6794116186646586 3 Q9Y4G8 1 +Glycosylase 0.6434108527131811 0.4792967919884275 0.6317275040350181 1.0 0.6794116186646586 2 P78549 1 +DNA glycosylase 0.6434108527131811 0.4792967919884275 0.6317275040350181 1.0 0.6794116186646586 2 P78549 1 +Storage 0.6233850129199004 0.4197843918344231 0.6746429680566568 1.0 0.708162154685161 2 P40855 1 +Glycosyltransferase 0.339687719517133 0.3616438308608535 0.7176182061955743 1.0 0.740840505878523 18 Q9BV10,Q8N128,Q9BT22,O60762,P46977,Q86SF2 6 +Protease 0.3377969353690378 0.3244329030371157 0.7456103126999369 1.0 0.7632046829524263 102 O75844,Q10713,Q9UIQ6,P22695,Q9H3G5,P42785,Q9NZ08,Q13510,P55786,O14773,Q96TA2,Q5BJF2,Q8NHP8,Q96K76,Q9HB40,P42892,Q7Z2K6 17 +Immune response 0.4008236974512362 0.2811143234329393 0.77862271546318 1.0 0.7953278600649542 6 Q9NX40 1 +Helicase 0.3078726406981583 0.17579344818887 0.8604562170689527 1.0 0.8761661636508064 22 P12956,P33991,Q96S55 3 +Phosphatase modulator 0.3631009489174787 0.1620995850414099 0.871227432964101 1.0 0.8848261962257675 6 P55209 1 +Hsp90 family chaperone 0.4065934065934085 0.1600420203286062 0.8728479733724555 1.0 0.8860110473338705 4 Q12931,P08238,P07900 3 +G-protein modulator 0.3002602472348754 0.1394873603413233 0.889065043284667 1.0 0.9005993588436274 24 O00410,Q96F07,P53367,P43487,P46940,Q9Y4G8,Q9H0H5,Q13576,Q8IZP0,Q7L576,Q96N67,Q6WCQ1,Q9H2M9,Q15437,Q14C86,P42566,Q96D71,O14530,P49792,Q9H223,P46060,P52565,Q9H4M9 23 +SRC family 0.4874031007752021 0.1343220886359522 0.8931478873116823 1.0 0.9040546373077852 2 P07947 1 +Aminoacyl-tRNA synthetase 0.3007919890377816 0.1340002785335857 0.8934023541837692 1.0 0.9040546373077852 19 Q9NSD9 1 +Non-motor microtubule binding protein 0.3145448655652704 0.0943608586418386 0.9248225073067408 1.0 0.9339128475234136 11 Q96CW5,Q14008,Q15555,Q9BSJ2,O43663,Q9BTW9,P60520,O94901,Q15691,Q9ULW0 10 +Methyltransferase 0.3022909915800346 0.0775172784965053 0.9382120463785192 1.0 0.9459658649436308 13 Q08J23 1 +Lysine-specific demethylase 0.3775839793281601 0.0563798043798785 0.9550392451313232 1.0 0.9619383934449656 2 Q8NB78 1 +Na+/K+-ATPases 0.4177705977382899 0.0549882388295103 0.9561478336710773 1.0 0.9625583142475208 3 P54709,P05023 2 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..39fdfb6e30fc306872c1778a48b0e0adb1393ed0 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2,4-dienoyl-CoA reductase, mitochondrial", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L41, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-aminobutyrate aminotransferase, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-1", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-methylcytosine rRNA methyltransferase NSUN4", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-1 complex subunit sigma-2", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP synthase-coupling factor 6, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family B member 8, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family D member 4", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase WRNIP1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "AUR family", "Abl interactor 1", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A synthetase 2-like, mitochondrial", "Acetyl-coenzyme A transporter 1", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Activating signal cointegrator 1", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine aminotransferase 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amyloid-like protein 2", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Anion exchange protein 2", "Anion exchangers", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Antigen peptide transporter 2", "Apoptosis regulator BAX", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arginase-2, mitochondrial", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical group", "Aurora kinase a", "Aurora kinase b", "B-cell receptor-associated protein 29", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2 homologous antagonist/killer", "Bcl-2-associated transcription factor 1", "Beta-galactosidase", "Beta-galactosidase-1-like protein 2", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 3", "Bromodomain-containing protein 4", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CDKN2A-interacting protein", "CHK1 subfamily", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CMGC group", "COMM domain-containing protein 5", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "COUP-TF-like receptors", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carbonyl reductase family member 4", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Cat eye syndrome critical region protein 2", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere protein C", "Centromere/kinetochore protein zw10 homolog", "Chaperone", "Chaperonin", "Charged multivesicular body protein 6", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Choline dehydrogenase, mitochondrial", "Choline transporter-like protein 1", "Choline/ethanolaminephosphotransferase 1", "Chondroitin sulfate N-acetylgalactosaminyltransferase 2", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 2", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 4", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collagen type IV alpha-3-binding protein", "Collectin-12", "Condensin complex subunit 1", "Copper-transporting ATPase 1", "Copper-transporting ATPase 2", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1C", "Coup transcription factor 2", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cu+-ATPases", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystatin-B", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DCK/DGK family", "DDB1- and CUL4-associated factor 13", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA topoisomerase 3-alpha", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(14)-sterol reductase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxyguanosine kinase, mitochondrial", "Deoxyribonuclease-2-alpha", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Derlin-2", "Desmocollin-1", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Dna-dependent protein kinase catalytic subunit", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase ZNF598", "EF-hand domain-containing protein D1", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER lumen protein-retaining receptor 3", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "ERO1-like protein beta", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endonuclease III-like protein 1", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 7", "Epidermal growth factor receptor substrate 15", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Estradiol 17-beta-dehydrogenase 8", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 1", "Exocyst complex component 3", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 6B", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferritin light chain", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Folate transporter 1", "Fragile X mental retardation syndrome-related protein 1", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "GC-rich sequence DNA-binding factor 2", "GDP-fucose protein O-fucosyltransferase 2", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General vesicular transport factor p115", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate exchanger SLC37A4", "Glucose-6-phosphate isomerase", "Glucose-induced degradation protein 8 homolog", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase catalytic subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--tRNA ligase", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi SNAP receptor complex member 2", "Golgi pH regulator family", "Golgi ph regulator b", "Graves disease carrier protein", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "H/ACA ribonucleoprotein complex subunit 3", "HBS1-like protein", "HDAC class I", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histidine triad nucleotide-binding protein 3", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase NSD3", "Histone-lysine N-methyltransferase SETD2", "Histone-lysine N-methyltransferase SMYD3", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "ILK subfamily", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of growth protein 5", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 3", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF18B", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIFC1", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LETM1 domain-containing protein 1", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Legumain", "Lethal(3)malignant brain tumor-like protein 3", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophosphatidylcholine acyltransferase 2", "Lysophospholipid acyltransferase 5", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "M-phase phosphoprotein 8", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAPK family", "MBT domain", "MCU family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB", "Mediator of RNA polymerase II transcription subunit 12", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 20", "Mediator of RNA polymerase II transcription subunit 25", "Mediator of RNA polymerase II transcription subunit 27", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine--tRNA ligase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Methyltransferase-like protein 7B", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial coenzyme A transporter SLC25A42", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import inner membrane translocase subunit Tim22", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multifunctional protein ADE2", "Muscleblind-like protein 1", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light chain 6B", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 12", "Myotubularin-related protein 2", "N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 50", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral cholesterol ester hydrolase 1", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear cap-binding protein subunit 2", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor", "Nuclear receptor coactivator 5", "Nuclear receptor corepressor 1", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase 6", "Nucleoside diphosphate kinase A", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "OCIA domain-containing protein 1", "Obg-like ATPase 1", "Occludin", "Origin recognition complex subunit 2", "Origin recognition complex subunit 3", "Origin recognition complex subunit 6", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P53-like transcription factor", "PAKB subfamily", "PAX3- and PAX7-binding protein 1", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PKC alpha subfamily", "PKC family", "PKN family", "PLK family", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 3", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal 2,4-dienoyl-CoA reductase", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal bifunctional enzyme", "Peroxisomal biogenesis factor 19", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phenylalanine--tRNA ligase, mitochondrial", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 3-kinase regulatory subunit beta", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylated adapter RNA export protein", "Plasma membrane calcium-transporting ATPase 1", "Plasma membrane calcium-transporting ATPase 4", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Platelet-activating factor acetylhydrolase 2, cytoplasmic", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polyhomeotic-like protein 2", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Pre-mRNA cleavage complex 2 protein Pcf11", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Prenylated Rab acceptor protein 1", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX37", "Probable E3 ubiquitin-protein ligase makorin-2", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable cysteine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable helicase with zinc finger domain", "Probable histidine--tRNA ligase, mitochondrial", "Probable leucine--tRNA ligase, mitochondrial", "Probable ribosome biogenesis protein RLP24", "Probable serine carboxypeptidase CPVL", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein NDRG3", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein S100-A13", "Protein SCAF8", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SYS1 homolog", "Protein Wiz", "Protein XRP2", "Protein angel homolog 1", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein gpr107", "Protein kinase", "Protein kinase c alpha type", "Protein kinase c beta type", "Protein lin-9 homolog", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1G", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec23B", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog A", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pterin-4-alpha-carbinolamine dehydratase", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RIPK family", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA polymerase II elongation factor ELL", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein FUS", "RNA-binding protein Nova-1", "RNA-binding protein with serine-rich domain 1", "RNA/RNP complex-1-interacting phosphatase", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor beta", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein R-Ras2", "Ras-related protein Ral-A", "Reader", "Receptor", "Receptor expression-enhancing protein 2", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Recombining binding protein suppressor of hairless", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinoic acid-induced protein 1", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal RNA-processing protein 7 homolog A", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "Ribosome-releasing factor 2, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "SAP30-binding protein", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC33 acetylCoA transporter", "SLC35 family of nucleotide sugar transporters", "SLC37 family of phosphosugar/phosphate exchangers", "SLC4 family of bicarbonate transporters", "SLC44 choline transporter-like family", "SLC5 family of sodium-dependent glucose transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STE group", "STE20 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Secretory carrier-associated membrane protein 4", "Sentrin-specific protease 3", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 11-interacting protein", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase chk1", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters", "Sodium-dependent HCO3- transporters", "Sodium-dependent multivitamin transporter", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 9", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 25 member 33", "Solute carrier family 25 member 40", "Solute carrier family 25 member 44", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 23", "Syntaxin-10", "Syntaxin-12", "Syntaxin-18", "Syntaxin-3", "Syntaxin-5", "Syntaxin-6", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "Syntenin-1", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TOPK family", "TP53-binding protein 1", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Testin", "Testis-specific Y-encoded-like protein 1", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Torsin-1A", "Torsin-1B", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription factor 20", "Transcription initiation factor IIB", "Transcription initiation factor TFIID subunit 9B", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor CTCF", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transducin-like enhancer protein 3", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation release factor", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 4", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Trypsin-3", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2B chain", "Tubulin beta-6 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase lyn", "Tyrosine-protein kinase yes", "Tyrosine-protein phosphatase non-receptor type 9", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP4", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm3", "U6 snRNA-associated Sm-like protein LSm4", "U6 snRNA-associated Sm-like protein LSm5", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "UDP-N-acetylglucosamine transporter", "UDP-glucose:glycoprotein glucosyltransferase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "UbiA prenyltransferase domain-containing protein 1", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 36", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Very long-chain acyl-CoA synthetase", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WEE family", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YLP motif-containing protein 1", "YSK subfamily", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCHC domain-containing protein 8", "Zinc finger E-box-binding homeobox 2", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 148", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein 644", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 5", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial", "tRNA pseudouridine synthase A"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG12", "ALYREF", "ANAPC1", "ANGEL1", "ANO6", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APLP2", "ARCN1", "ARFIP1", "ARG2", "ARHGDIA", "ARID3B", "ARPC1A", "ARPC3", "ARPC4", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATIC", "ATL2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "BAG6", "BAIAP2", "BAK1", "BAX", "BCAP29", "BCAP31", "BCAS2", "BCAT2", "BCKDHB", "BCLAF1", "BLMH", "BLVRA", "BOP1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIX1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC37", "CDC40", "CDC42", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKN2AIP", "CEBPZ", "CECR2", "CENPC", "CEPT1", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHDH", "CHEK1", "CHERP", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNP", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPOX", "CPSF1", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBT", "DCAF13", "DCPS", "DCTN1", "DCTN2", "DDB1", "DDI2", "DDOST", "DDT", "DECR1", "DECR2", "DENR", "DERL1", "DERL2", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIS3", "DLD", "DLST", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUSP11", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "EPHA7", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERH", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FAM177A1", "FARS2", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FOXRED1", "FSCN1", "FTL", "FUBP1", "FUBP3", "FUS", "FXR1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GCAT", "GCFC2", "GCLC", "GCN1", "GDI2", "GFM2", "GGH", "GID8", "GLB1", "GLB1L2", "GLDC", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNPDA1", "GNS", "GOSR1", "GOSR2", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPR107", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2F2", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HEATR1", "HEATR6", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HPRT1", "HSD17B10", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPAD1", "IMPDH2", "ING5", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "IVD", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LETMD1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LRRC47", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LYN", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A2", "MAPK1", "MAPRE1", "MAPRE2", "MARCH5", "MARS2", "MAT2A", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED12", "MED14", "MED20", "MED25", "MED27", "METTL7B", "MFAP1", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MKRN2", "MMS19", "MORF4L1", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL14", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL38", "MRPL39", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL48", "MRPL49", "MRPL9", "MRPS11", "MRPS16", "MRPS18A", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA50", "NADK2", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCBP1", "NCBP2", "NCEH1", "NCL", "NCOA5", "NCOR1", "ND1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEDD4L", "NEK9", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA1", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN3", "NSUN4", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCLN", "OLA1", "OPA1", "ORC2", "ORC3", "ORC6", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "PAFAH2", "PAICS", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDHX", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF10", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIK3C2A", "PIK3R2", "PIK3R4", "PINX1", "PIP4K2C", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNP", "PNPLA6", "PNPT1", "POFUT2", "POGZ", "POLA2", "POLD2", "POLDIP3", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL3", "PPM1G", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA1", "PRKAA2", "PRKAG1", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2B", "PRRC2C", "PRSS3", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPN9", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "RAB3GAP2", "RABAC1", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIPK1", "RNASEH2A", "RNH1", "RNPS1", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "S100A10", "S100A11", "S100A13", "SAE1", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIN3A", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMN1*", "SMYD3", "SNAP23", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SPAG9", "SPCS2", "SPCS3", "SPNS1", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAT1", "STAT3", "STK11IP", "STK26", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUPT16H", "SUPT6H", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM22", "TJP1", "TK1", "TKT", "TLE3", "TM7SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM165", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOP3A", "TOR1A", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRIP4", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TST", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA6", "UBE2L3", "UBIAD1", "UCHL5", "UGGT1", "UNC119", "UNC119B", "UPF1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP5", "USP7", "UTP11", "UTP14A", "UTP3", "UTP6", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VRK1", "VRK2", "WARS", "WDHD1", "WDR1", "WDR33", "WDR74", "WDR82", "WIZ", "WRNIP1", "XAB2", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS2", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZCCHC8", "ZEB2", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF148", "ZNF281", "ZNF598", "ZNF622", "ZNF644", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCB7", "ABCC1", "ABCD4", "ABI1", "ACOX3", "ACP2", "ACP6", "AIFM1", "ALDH1B1", "ALG1", "ALG12", "AP3B1", "ARFIP1", "ARHGDIA", "ASAH1", "ASNA1", "ATAD3B", "ATL2", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5B", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP7A", "ATP7B", "BAIAP2", "BAX", "BCAP31", "CCAR2", "CDK4", "CDK9", "CETN2", "CKAP5", "COLEC12", "COPS8", "COX5A", "COX7A2", "CPVL", "CRTAP", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DHCR24", "DNM2", "DOCK7", "DOLPP1", "DPM1", "ECE1", "EHD1", "EHD4", "EIF3F", "EIF5", "EPS15", "ERAP1", "ERMP1", "EXOC6B", "FAM177A1", "FARSB", "GABARAPL2", "GALNT7", "GAPVD1", "GLB1", "GNA13", "GNAI1", "GNAI2", "GNG5", "GOSR1", "GOSR2", "GPR89B", "HEXA", "HINT2", "HSP90AA1", "HSP90AB1", "IPO11", "IPO5", "IPO9", "IQGAP1", "IQGAP2", "KDELR1", "KDELR3", "KDM1B", "LETM1", "LNPEP", "MAPRE1", "MAPRE2", "MCL1", "MCM4", "MFAP1", "MIA2", "MIA3", "MPC2", "MPRIP", "MPV17L2", "MSMO1", "MTCH1", "MTCH2", "MYL6B", "NAMPT", "NAP1L1", "NCEH1", "ND1", "NDUFA13", "NNT", "NPEPPS", "NRDC", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NUCB1", "NUCB2", "NUP107", "NUP54", "NUP93", "OCIAD1", "OPA1", "OXA1L", "P3H1", "PEX14", "PEX19", "PGRMC1", "PGRMC2", "PLA2G15", "PLBD2", "PMPCA", "PNPLA6", "PPP4R1", "PPT1", "PPT2", "PRC1", "PRCP", "PSMD7", "PTGES2", "PXMP2", "RAB3GAP2", "RABAC1", "RACGAP1", "RANBP1", "RANBP2", "RANGAP1", "RAPGEF2", "RCN2", "REEP2", "REEP5", "REPS1", "RPRD1A", "RPRD1B", "RPRD2", "RRAS2", "SCARB1", "SCARB2", "SCO2", "SCPEP1", "SDF4", "SEC23B", "SEH1L", "SFXN2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A40", "SLC25A42", "SLC25A44", "SLC33A1", "SLC35B2", "SLC35F2", "SLC4A7", "SLC7A1", "SNX2", "SPNS1", "SSR1", "STT3A", "STX10", "STX18", "STX3", "STX6", "STX7", "STX8", "SUN1", "SYNGR2", "SYS1", "TAP1", "TBCD", "TIMM22", "TM7SF2", "TM9SF3", "TMED2", "TMED7", "TMED9", "TMEM165", "TMEM97", "TOMM20", "TPBG", "TPP1", "TPX2", "TRAP1", "TTYH3", "TUBB", "TUBB2B", "TUBGCP2", "TUBGCP3", "TXNDC9", "UNC119", "UNC119B", "UQCR10", "UQCRC2", "USP47", "VKORC1L1", "VPS45", "WRNIP1", "XRCC6", "YES1", "YME1L1", "ZADH2", "ZMPSTE24", "ZMYM2"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..52a0ecc67e1a13406e70d63354ed5a879b6bad58 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tclin", "1": "Tdark", "2": "Tbio"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..071f14c660a22ca903ffb2289169deaa09a6915a --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:02837590ebc70bada4d4ef8274fdad3113099a0b4af0d881db3062ae9a4d51ce +size 138918 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..35767a67a54e786994c995c837026b81c95b8267 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3a29a6bd90fb5fcaf56d3947bc817c181917dec91c9e00fddd13128a0a18f9dc +size 135947 diff --git a/pharos_protein_category/basic/plot_2.png b/pharos_protein_category/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..c43ea73f05d3653c3dc574d42f11ca4fc95b4e94 --- /dev/null +++ b/pharos_protein_category/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:81e8d6c5863185d4f3780400bca326e64da302ab84a4667f3f83b269dcd33daa +size 126267 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..1d9ad0be62776cb096e2e5c89ef5fca721db4571 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:13edd7b6828a9b78c911cba156b34d0d3c8f1dd285abc0d8de3925db8ba8343a +size 68236 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b7e7bf9cbc49504e111152127047ad0012b4e741 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 774.25 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d1a977dce5f4fa5d82ec47c03abdebcc3725642a --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e755715e881a89141054d5e07e3f6634015c131c --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tclin 0.4017735341528571 0.9291389295257916 0.3528170917821771 0.8245682656110442 0.7056341835643543 79 Q99720,O95182,O75306,P03886,P20618,O43676,Q06203,Q9BVA1,Q14145,P14324,P07437,P21964,O95168,P49721,P31350,Q86Y39,O96000,P38435,P28074,Q9BUF5,Q16718,P10253,P06280,P00390,Q9Y375,Q9P0J0,O75380 27 +Tdark 0.3393010326818323 0.5178040551149358 0.6045949887528406 0.9755562025393284 0.806126651670454 347 Q9Y3E0,Q8N128,Q8WUJ1,Q9BRK0,P14649,O60830,Q5VW38,Q96NB2,Q96HV5,Q9P0I2,P0CG08,Q8N2H4,Q9NPL8,Q6UW02,Q96GQ5,Q9NRY5,Q70UQ0,Q3SXM5,Q96CN7,Q9BTE7,Q9NPR9,Q6UW68,Q9H1E5,Q5SWX8,P14406,Q69YU5,O75964,Q9H4I3,Q9GZU8,Q8N6N3,Q969T7,O43731,Q96H78,Q96EX1,Q8IXU6,Q7Z4Q2,Q6YN16,Q96DB5,Q8N4H5,Q8WVI0,Q9NSI2,Q8NBM8,Q9P0S9,O94919,Q9HD20,O60476,Q9Y3B3,O95302,Q9NUQ9,Q86YN1,A4D1U4,Q15629,Q7Z2K6,Q96CP7,Q9P260,O95070,Q9Y4Y9,O75935,Q9Y5M8,Q92575,Q9NU23,Q8NC96,Q9NR77,Q4VC44,Q8TBP6 65 +Tbio 0.1701132573900342 0.1114936029087527 0.9112249381131144 0.9999378896559554 0.9112249381131144 2374 P00846,Q14108,P46379,Q9H6V9,Q99595,Q9NPH0,Q9UMR5,Q9HCL2,O60637,P21796,Q567V2,Q70HW3,Q9BZF3,Q9Y584,Q9Y487,Q9H307,O43169,Q9HB40,Q9C0H2,Q16740,Q8N511,P49458,P24390,P50897,Q9H061,Q93050,Q8NHS3,Q9UDX5,O95197,Q9NS69,P55010,Q86XL3,Q8NCC3,Q9BRR6,O15118,Q9H6K4,Q8N0U8,P12956,Q9H6D7,P62072,Q13423,Q13505,O43772,Q6IPU0,Q9NSD9,Q8WY22,Q92896,P98194,Q8NDZ4,O75153,P80303,O75503,Q5KU26,Q8N4Q0,P62310,Q9NR50,Q9UMX5,Q9UDW1,Q9UHX1,Q9UQB8,Q9Y282,O75844,P43307,Q15165,Q96DY7,Q13011,Q9UQ84,Q9UNW1,Q07065,Q6P4A7,P22830,Q14257,Q9P2W9,Q4VCS5,P54802,Q08J23,Q9UHG3,P11117,Q8NHP8,Q9BSK2,Q9UI14,Q8NBX0,P49902,Q9UJX3,Q8IY17,Q03518,A6NIH7,O15173,O43681,Q9NUJ1,Q9BWD1,O15254,Q15047,Q96A26,Q9UL15,O00461,P07602,O00584,O95831,Q8IZA0,Q8NCH0,P27105,Q13641,Q9HA77,O43760,Q5BJH7,Q7KZN9,Q96G23,O94927,Q53GQ0,Q9BT22,Q9BTX1,Q9BT78,Q9Y2R0,Q15392,Q9BQT8,Q9UM22,O14737,Q99536,P33991,Q9UBX3,Q53H12,Q5XKP0,Q8TF05,Q8WU17,P13073,Q8N163,Q9H3P7,P50748,P22695,Q9H3G5,Q9NQX7,Q13277,Q9NR45,Q16625,Q9BRK5,P35914,P41208,P08670,Q15800,Q6P1K2,P51648,Q8WUB8,P20674,O76062,Q6DKK2,O14653,O75431,Q13794,Q99956,Q9UBB6,Q9Y6M7,Q9UBV2,P30825,O75298,O95202,P98179,Q9HC07,Q9NX40,O43819,O60499,P49005,Q8IXB1,Q96TA2,P46977,Q5T9A4,Q10713,Q9UNK0,O43657,O14773,P30837,Q06136,Q15070,O43752,O95456,P16615,Q00765,Q9H2V7,Q96RT1,O96005,P07196,Q9NRV9,Q96PC5,Q9BZK7,Q71SY5,O15127,P67812,Q16204,O14734,Q12981,Q13586,Q8NFF5,Q9NWM8,Q9UJS0,Q15363,Q86VD7,P04899,P46783,O14949,Q9BU89,Q9H3N1,Q9NQC3,Q9UGP8,Q9UJZ1,Q9Y5X1,Q9Y6K0,P28070,P49366,Q15388,Q8TB61,Q969T9,Q96A33,Q9BRX5,Q9NQ88,Q9GZM5,Q99943,O75976,Q9Y619,Q9H6E4,Q96EE3,P16989,O95453,O75381,P31942,P50402,Q9BRT9,P51572,Q9NVT9,Q96PU5,Q92530,O00203,O43791,O75746,P55209,Q9Y277,Q9Y6C9,Q9BXS4,P16435,P42167,O95249,O00231,Q9BUK6,Q9UI26,Q9NR56,Q9H2D1,P06576,Q16629,P09669,O94813,O75787,P55081,Q8NEY8,Q9Y679,Q9UMS0,Q5VV42,O75718,P20700,P52597,Q96DF8,Q9UEY8,Q8TB37,Q9H6W3,Q9HBH5,Q14728,O94923,P61457,Q07866,Q9UJW0,Q96KC8,Q96HY6,Q96F07,Q8IXH7,Q6NUQ1,O75955,O60925,Q08380,Q9BQP7,Q8WWY3,O75880,O43505,Q9NVN8,Q9P287,O75915,O75027,O60749,P83916,Q8IY67,Q9BV57,Q9UP83,O15400,Q92667,Q9UBG0,Q92766,Q96RQ1,P51665,Q08722,P10321,Q92804,Q9NVI7,Q9BSR8,O60762,Q99417,Q32P28,Q15102,Q03252,P16260,Q86SF2,Q6WCQ1,Q9Y5Z9,Q9BXW9,Q99733,Q8WWI1,Q8N1F7,Q5JRA6,P78318,P61916,P28072,Q6PGP7,Q9UL46,Q9NZW5,Q8NHH9,Q96N66,P61978,O95563,O43852,O43847,A1L0T0,P20020,Q96B26,Q96BW9,Q96S55,Q9NVR5,Q9Y5K8,Q96AG4,Q9NUQ7,Q96IZ0,Q92879,P60602,O00303,Q8N3U4,Q9UBB4 341 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..07c31098b51bdf08b6ee54acf269cfa62e003cd3 --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf35", "C1orf52", "C2CD5", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf33", "CAAP1", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC59", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPI", "CENPL", "CENPP", "CENPQ", "CENPU", "CENPV", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLK", "DOLPP1", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM114A2", "FAM120A", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM207A", "FAM208A", "FAM208B", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMC1", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LETMD1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM12", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "M6PR", "MACF1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NEPRO", "NES", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2B", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "ROMO1", "RP2", "RPA1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RSRC1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35A4", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPNS1", "SPOP", "SPOUT1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THEM6", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THYN1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM29", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF3", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED8", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM19", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM223", "TMEM230", "TMEM245", "TMEM33", "TMEM41A", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBFD1", "UBIAD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "UROD", "USMG5", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZCCHC17", "ZCCHC3", "ZCCHC8", "ZDHHC20", "ZEB2", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF148", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF644", "ZPR1", "ZRANB2", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["ABCB7", "ABHD10", "ACAT2", "ACBD3", "ACOT8", "ACOX3", "ACP2", "ACP6", "ADD3", "ADI1", "ADPGK", "AGK", "AGPAT1", "AIFM1", "AKAP1", "ALDH1B1", "ALDH3A2", "ALG1", "AMOT", "ANAPC7", "ANKLE2", "AP3B1", "ARL6IP5", "ARMC1", "ASNA1", "ATAD3A", "ATAD3B", "ATL2", "ATP13A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP5L", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATXN10", "AUP1", "B4GAT1", "BAG5", "BAG6", "BAIAP2", "BCAP31", "BCCIP", "BNIP1", "BRI3BP", "C12orf73", "C16orf58", "C19orf70", "C1orf52", "C3orf58", "CALU", "CARS2", "CBX1", "CCAR2", "CCDC134", "CCDC47", "CCDC6", "CD47", "CDKAL1", "CELF1", "CENPP", "CEPT1", "CERS2", "CETN2", "CHST14", "CKAP4", "CLN5", "CLPP", "CLPTM1", "CLUH", "COA3", "COG5", "COLEC12", "COMT", "COPS4", "COX15", "COX4I1", "COX5A", "COX6C", "COX7A2", "CPD", "CPVL", "CRTAP", "CYB5B", "CYB5D2", "CYFIP2", "CYP20A1", "DCTN3", "DCTN4", "DCUN1D5", "DDRGK1", "DHCR24", "DHPS", "DNAAF2", "DNAJC1", "DNAJC10", "DOHH", "DOLPP1", "DPM1", "DUSP9", "ECH1", "EIF2B3", "EIF3F", "EIF5", "EMC3", "EMD", "ENDOD1", "EPDR1", "ERBIN", "ERGIC2", "ERGIC3", "ERMP1", "ESS2", "EXO1", "EXOSC8", "FAM114A2", "FAM162A", "FAM177A1", "FAM192A", "FAM207A", "FAM49B", "FANCD2", "FARSB", "FDPS", "FECH", "FKBP14", "FKBP9", "FLAD1", "FLOT1", "FLYWCH1", "GAA", "GALNT7", "GGCX", "GINS3", "GINS4", "GLA", "GLCE", "GLG1", "GNAI2", "GNL3L", "GOLIM4", "GOLT1B", "GOSR1", "GOSR2", "GPAM", "GPR107", "GPR108", "GPR89B", "GSR", "HAUS4", "HAUS5", "HEATR3", "HEBP1", "HLA-C", "HMGCL", "HNRNPF", "HNRNPH3", "HNRNPK", "HSD17B12", "HSDL1", "HSDL2", "IGBP1", "IKBIP", "ILVBL", "IPO11", "ISOC1", "ITM2C", "KDELR1", "KDELR3", "KDSR", "KEAP1", "KIAA0319L", "KIAA1147", "KIAA1468", "KLC1", "KNTC1", "LDAH", "LETM1", "LGALS3BP", "LMNB1", "LMNB2", "LMO7", "LRRC59", "LSM3", "LSM5", "LYRM2", "MAN1A2", "MBNL1", "MBOAT7", "MCM4", "MED25", "MFAP1", "MFSD10", "MFSD8", "MGME1", "MIA2", "MIA3", "MINPP1", "MPC2", "MPP6", "MPRIP", "MPV17L2", "MRC2", "MSMO1", "MSTO1", "MTBP", "MTCH2", "MTFP1", "MTX1", "MTX2", "MYCBP", "MYL6B", "NAGLU", "NANS", "NAP1L1", "NAP1L4", "NCDN", "ND1", "NDC1", "NDUFA11", "NDUFA13", "NDUFA5", "NDUFA7", "NDUFAF1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFS2", "NDUFS6", "NECAP1", "NEDD4L", "NEFL", "NELFCD", "NENF", "NFU1", "NNT", "NPC1", "NPC2", "NRDC", "NSUN2", "NT5C2", "NT5C3B", "NUBPL", "NUCB2", "NUP93", "OCIAD1", "OCLN", "ODR4", "OPA3", "OSBPL6", "OXA1L", "P3H1", "PAFAH1B3", "PARN", "PAWR", "PCBD1", "PCYOX1", "PCYOX1L", "PDCD5", "PEX14", "PFDN1", "PGRMC2", "PHF10", "PLA2G15", "PLBD2", "PMAIP1", "PMF1", "PMPCA", "PNN", "PNPLA6", "POLD2", "PON2", "POR", "PPAT", "PPHLN1", "PPP4R1", "PPT1", "PPT2", "PRPF31", "PSAP", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMD11", "PSMD7", "PSME2", "PSMF1", "PSMG1", "PUF60", "PXMP2", "RABAC1", "RAVER1", "RBM3", "RCN2", "RDH14", "REEP2", "REEP5", "RINT1", "RIOX1", "RMDN1", "RNASET2", "RNF139", "ROMO1", "RPS10", "RREB1", "RRM2", "RTN2", "RTN3", "RTN4", "SCAMP2", "SCARB2", "SCCPDH", "SCO1", "SCO2", "SCPEP1", "SDF4", "SEC11A", "SEC63", "SEH1L", "SEL1L", "SETDB1", "SFXN2", "SFXN4", "SIGMAR1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A40", "SLC25A42", 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a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..48d4c6bc58114b8b36e8d8663299cabb49200672 --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,49 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transport 0.4750715271521614 2.728677530062581 0.0063588852209723 0.6683250001856007 0.1501538587437543 501 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O43615,Q8N1F7,Q96EE3,Q9BTX1,Q99595,O60830,O75381,Q9NS69,P41208,P57740,Q9Y584,Q15629,Q7Z3B4,P62072 14 +Calcium transport 0.704851356019848 1.9947630957240745 0.0460687241267212 0.9997139406077652 0.2656629757974258 10 P16615,P98194,O95202,P20020,Q13586 5 +Antiport 0.7281859609946776 1.9115269397791093 0.0559368981740753 0.9999526655735594 0.2791578063706766 8 P51790,P41440 2 +Vision 0.7808278444506866 1.9073366056958216 0.0564770128495588 0.9999571273851076 0.2791578063706766 6 Q9H6K4,P50897 2 +Sensory transduction 0.7808278444506866 1.9073366056958216 0.0564770128495588 0.9999571273851076 0.2791578063706766 6 Q9H6K4,P50897 2 +Lipid transport 0.5440398743293826 1.8421957153523136 0.0654465269576138 0.9999917866761112 0.2978229734404892 22 Q99720,P61916,Q9H2V7,Q9BZF3,O15118,P04114,Q9P260 7 +ER-Golgi transport 0.4917067463805405 1.8307405132330532 0.0671392830299368 0.9999939978437208 0.2978229734404892 48 Q15363,O95249,P24390,O95070,Q6NUQ1,Q96RQ1,O95197,Q9P2W9,P51572,O43731,Q12981,Q9Y282 12 +Cholesterol biosynthesis 0.565607990205758 1.7256808017834746 0.0844048537432449 0.999999763025105 0.3650509924395342 15 P37268,Q15800,Q15392,Q16850 4 +Protein transport 0.3679275111590594 1.60627656471656 0.1082131571415103 0.999999997515932 0.4254744587609385 242 O43615,Q9Y2D4,Q03518,O43823,A6NIH7,Q9Y3E0,O43752,Q6NUQ1,Q99595,O60830,Q9NRW7,P49321,Q5VZ89,P0CG08,Q8N2H4,P57740,Q96P70,Q969Q5,Q9Y584,Q6WKZ4,O15127,Q5BJH7,O14925,O60749,Q15363,P24390,Q9UP83,Q9BTX1,Q9UGP8,O75396,Q9NS69,Q9Y5X1,Q15388,O43731,P52292,P62072,Q13505,Q8N1F7,Q8N4H5,Q5JRA6,Q96EE3,O75381,Q9HD20,P41208,Q13432,Q9Y3B3,P51572,O00203,Q15629,O14653,O75431,O95249,O95070,Q9BVK6,Q9UI26,Q9P2W9,O60831,P83436,Q8NC96,O60499,Q9NV70,Q9H4M9,Q7Z3B4,P61019 64 +Steroid biosynthesis 0.4984173417938884 1.5829501429873694 0.1134328285293435 0.9999999991002648 0.4282599163237187 24 Q53GQ0,Q9H3P7,P37268,Q15392,Q15800,Q16850 6 +Lipid degradation 0.5554126905261803 1.566939588725614 0.1171288129561465 0.9999999995632424 0.4282599163237187 14 Q8NCC3,Q8NHP8,Q9H6V9,Q8IY17 4 +Sterol biosynthesis 0.52119861103678 1.564977806311646 0.1175881132783867 0.9999999996008432 0.4282599163237187 17 P37268,Q15800,Q15392,Q16850 4 +Electron transport 0.4591722429697962 1.5312318222854149 0.1257121086278512 0.9999999999194208 0.429899386983758 50 O43676,O96000,O95182,P22695,Q9UDW1,O14949,Q9H1E5,Q9H3N1,Q6DKK2,P00403,P03886,Q9P0J0,O43169 13 +Cholesterol metabolism 0.4811048742433793 1.5271112686740715 0.1267333452957899 0.999999999934172 0.429899386983758 26 P37268,Q15392,Q15800,O15118,Q16850 5 +Symport 0.6620434098325215 1.4641522821580348 0.1431523448476865 0.999999999997532 0.4586176973824032 7 Q9Y6M7,Q15758,P53985 3 +Hypusine biosynthesis 0.9011627906976748 1.4351098516485992 0.1512557966575962 0.9999999999995232 0.467272371817217 2 Q9BU89 1 +Sterol metabolism 0.4550632713006217 1.4065648951570695 0.1595564487540473 0.999999999999913 0.4759183730077617 28 P37268,Q15392,Q15800,O15118,Q16850 5 +DNA excision 0.8925037543196728 1.3184118564860894 0.1873658138965424 0.9999999999999998 0.5172707979225835 3 Q9UQ84 1 +Steroid metabolism 0.4384402020475236 1.3162416841831313 0.1880929369516113 0.9999999999999998 0.5172707979225835 29 P37268,Q15392,Q15800,O15118,Q16850 5 +Phospholipid metabolism 0.440345050169709 1.0462340089950692 0.2954530046757151 1.0 0.6725443395907725 19 Q9NPH0,Q96N66,Q9Y6K0,Q9HCL2,Q99943 5 +Heme biosynthesis 0.5786288614984791 1.0156697519206876 0.3097866767525823 1.0 0.6783936085847688 6 P22830,Q9P0S9 2 +Copper transport 0.7729328165374701 0.931985043672298 0.3513442548847139 1.0 0.6918664557107337 2 P35670 1 +Spermatogenesis 0.4202653092466202 0.9193988762645308 0.3578869768831794 1.0 0.6918664557107337 20 P46379 1 +Sphingolipid metabolism 0.5020033746899741 0.888205727894542 0.3744300982545265 1.0 0.6968649560506566 9 O95470,P07602,Q06136,Q13510 4 +Nucleotide metabolism 0.5010255526310834 0.8264277024429751 0.40856151419568 1.0 0.7192768186618134 8 Q969T7 1 +Leukotriene biosynthesis 0.7338501291989652 0.7860643934658942 0.4318297630998429 1.0 0.7281690420024327 2 P09960 1 +Sodium transport 0.5251590256317594 0.7788192461952664 0.4360861987204476 1.0 0.7281690420024327 6 P55011,Q9Y6M7,P05023 3 +Neurogenesis 0.3696309410294843 0.7760097329442344 0.4377432391228497 1.0 0.7281690420024327 41 Q9Y4G8,P55209,Q8WUJ1,Q9NQC3,O94813,Q9BVA1,Q8WUB8,Q15375 8 +Apoptosis 0.3583486946961382 0.7245568592340162 0.4687239331121982 1.0 0.7462379741168936 118 Q9H2J4,P46379,Q96F07,Q96A26,O95470,O15294,P31751,P21796,O95831,Q9NZJ7,Q12981,Q9UDX5,O95197,O43464,Q6FI81,O14737,Q15375,Q9NQ88,O95817,Q8N163,O14681,Q07812,Q9BX68,P09601,P51572,O60313,Q9UHX1,Q96IZ0,Q13794,Q9P0J0,Q14728 31 +Porphyrin biosynthesis 0.5588897200349536 0.6127740207566289 0.5400257709914762 1.0 0.7984996442865416 4 P22830 1 +Cell shape 0.5008082767539701 0.5697009955680684 0.5688805147176579 1.0 0.8152967537951379 5 P35579,Q7L576,Q96AC1,P35580 4 +Biomineralization 0.635012919896625 0.453887967498222 0.6499094643990591 1.0 0.8328469432669423 2 Q6P4Q7 1 +Viral RNA replication 0.6288759689922493 0.4357287965522862 0.6630335100967273 1.0 0.8372612937717797 2 Q15366 1 +Lipid metabolism 0.3021769120352914 0.3896428938757835 0.6968006293521358 1.0 0.867241071064169 141 Q9H7Z7,Q9H6V9,O15254,P48449,O95470,Q9NPH0,P07602,Q9HCL2,P04114,O14734,O15269,Q96G23,Q53GQ0,P37268,Q15392,Q13510,Q9Y6K0,Q8NCC3,O15118,Q16850,Q15102,Q99943,Q9H3P7,P61916,Q6PIU2,Q96N66,A1L0T0,Q15800,P09960,P51648,O76062,P50416,Q13011,P23786,Q8NHP8,Q06136,Q8IY17 37 +Potassium transport 0.4348457764454423 0.3312967665387923 0.7404203334646069 1.0 0.8833980530301861 5 Q9NUT2,P05023 2 +Meiosis 0.3459658554617897 0.3095427225284246 0.7569087188842292 1.0 0.8859509492837141 14 Q8N3U4,Q9UQ84 2 +Phospholipid biosynthesis 0.3298255356394982 0.3014852981145899 0.7630444592096728 1.0 0.8859509492837141 18 Q9Y6K0,Q99943,Q96N66,Q9HCL2 4 +DNA synthesis 0.5344888473269764 0.2026719143452228 0.8393914766811281 1.0 0.9429527627651634 3 P04183 1 +Ubiquinone biosynthesis 0.5214320211608419 0.1788592388646208 0.8580482292776968 1.0 0.9515534850323176 3 Q9Y5Z9 1 +Fucose metabolism 0.4625322997416033 0.1064520817553485 0.915223672522522 1.0 0.989585595914977 2 Q9Y2G5 1 +Sodium/potassium transport 0.4177705977382899 0.0549882388295103 0.9561478336710773 1.0 1.0 3 P54709,P05023 2 +Immunity 0.3059366839221666 0.0314556077415497 0.9749061945002055 1.0 1.0 68 Q03518,P46379,Q9UQ84,Q9NZ08,O00584,P12956 6 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0c50b975a31d8d6266c20ea6d79e5dde9ef0a9cf --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Anion exchange", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Copper transport", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "Digestion", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Ion transport", "Iron storage", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Menaquinone biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sexual differentiation", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT2", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALG13", "ALKBH5", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEX1", "API5", "APOB", "APOO", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARG2", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL8A", "ARL8B", "ARMC10", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATG3", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATRIP", "ATRX", "AUP1", "AURKA", "AURKB", "BABAM2", "BAG3", "BAG6", "BAHD1", "BAK1", "BANF1", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BICD2", "BIRC6", "BLM", "BMI1", "BMS1", "BNIP1", "BOP1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C2CD5", "CAAP1", "CACYBP", "CAD", "CAMK2G", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CARS2", "CBR4", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC59", "CCDC86", "CCDC93", "CCNB1", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC34", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CEBPZ", "CELF1", "CELF2", "CENPC", "CENPU", "CENPV", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CGGBP1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHST14", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLIC1", "CLPTM1", "CLPTM1L", "CLSPN", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "COG2", "COG5", "COG6", "COG7", "COL4A3BP", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS6", "COPZ1", "COQ8A", "COQ9", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCPS", "DCTN1", "DCTN3", "DCXR", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DECR1", "DECR2", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX15", "DHX16", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLST", "DMAP1", "DNAAF5", "DNAJB1", "DNAJB12", "DNAJC13", "DNAJC19", "DNAJC3", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPYSL2", "DSC1", "DSC3", "DSG2", "DST", "DTYMK", "DUS2", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECH1", "ECHS1", "ECI1", "ECSIT", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFL1", "EFTUD2", "EHD1", "EHHADH", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC4", "EMG1", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESCO2", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAM162A", "FAM208A", "FANCD2", "FANCI", "FAR1", "FAR2", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXK1", "FOXRED1", "FRYL", "FTL", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCFC2", "GCLC", "GCN1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GHITM", "GID8", "GINS3", "GINS4", "GLRX", "GM2A", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPI", "GPR89B", "GRB2", "GRSF1", "GRWD1", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HELLS", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGXB4", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD11", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILVBL", "IMP4", "IMPDH2", "INA", "INCENP", "ING5", "INTS13", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BP1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDLR", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LMAN1", "LMAN2", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPPRC", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L3", "LYAR", "LYN", "LYPLA1", "M6PR", "MACF1", "MAEA", "MAGT1", "MANF", "MAPK1", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MESD", "MFAP1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGEA5", "MGME1", "MGST2", "MIA3", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MKRN2", "MLEC", "MMS19", "MOCS1", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL41", "MRPL58", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MYBBP1A", "MYCBP", "MYDGF", "MYH10", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCEH1", "NCKAP1", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NME1", "NME6", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP10", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPM1", "NR2F2", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUBP1", "NUCKS1", "NUDC", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OGDH", "OGT", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "PA2G4", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCF11", "PCID2", "PCK2", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDK1", "PDK3", "PDS5A", "PDS5B", "PDZD8", "PECR", "PEDS1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGP", "PGS1", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHGDH", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIN1", "PISD", "PITPNB", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLIN3", "PLK1", "PLRG1", "PMAIP1", "PMF1", "PMVK", "PNN", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "POP1", "PPAT", "PPHLN1", "PPID", "PPIE", "PPIF", "PPIH", "PPIL3", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKCA", "PRKCB", "PRKDC", "PRKRA", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK7", "PTPMT1", "PTRH2", "PUF60", "PURA", "PUS1", "PWP1", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB35", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM14", "RBM15", "RBM17", "RBM22", "RBM23", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCOR1", "REEP3", "REEP4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN3", "RMND1", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPS1", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP14", "RPP30", "RPP38", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RPUSD3", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSF1", "RSL24D1", "RSRC1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDF4", "SDHA", "SDHB", "SDHC", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35B2", "SLC35F2", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMU1", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOAT1", "SON", "SPATA5", "SPC25", "SPECC1L", "SPEN", "SPNS1", "SPOP", "SPOUT1", "SPTLC1", "SPTLC2", "SRCAP", "SREK1", "SRFBP1", "SRM", "SRPK1", "SRPK2", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STK26", "STMN1", "STRAP", "STRBP", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNGR2", "SYS1", "TACO1", "TADA3", "TAF6L", "TAF9B", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBCB", "TBL1XR1", "TCEA1", "TCERG1", "TCF20", "TDRKH", "TECR", "TEFM", "TERF2", "TERF2IP", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM29", "TIMM44", "TIMM50", "TIMM8B", "TK1", "TLE3", "TLN1", "TM7SF2", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM14C", "TMEM214", "TMEM59", "TMF1", "TMX1", "TMX4", "TNPO1", "TNPO3", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TP53", "TP53BP1", "TPI1", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TSFM", "TSG101", "TSNAX", "TTC19", "TTC26", "TTC4", "TTF1", "TTLL12", "TTYH3", "TUBB2B", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC15", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBIAD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VPS13A", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WASHC4", "WBP11", "WDR12", "WDR33", "WDR36", "WDR41", "WDR43", "WDR5", "WDR6", "WDR61", "WDR75", "WIPI2", "WRNIP1", "WTAP", "XAB2", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YKT6", "YLPM1", "YTHDC1", "YWHAB", "YWHAE", "ZC3H11A", "ZC3H13", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZEB2", "ZMYM2", "ZMYND8", "ZNF148", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZPR1", "ZRANB2", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["ABCB1", "ABCB7", "ABCB8", "ABCC1", "ABCD4", "ACBD3", "ACOT8", "ACOX3", "ACP6", "AGPAT1", "AIFM1", "AKAP8", "AKT2", "ALDH3A2", "ANO6", "AP3B1", "APOB", "ASAH1", "ASNA1", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP5L", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP7B", "BAG3", "BAG6", "BAX", "BCAP31", "BNIP1", "CCAR2", "CEPT1", "CERS2", "CETN2", "CIAPIN1", "CLCN3", "CNNM4", "COG5", "COG7", "COX2", "CPT1A", "CPT2", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DENND4C", "DHCR24", "DOHH", "ECH1", "EHD1", "EI24", "EPHA7", "ERAP1", "ERGIC2", "ERGIC3", "EXO1", "EXOC1", "EXOC6B", "FAM162A", "FDFT1", "FECH", "FERMT2", "FOXRED1", "GOLIM4", "GOLT1B", "GOSR1", "GOSR2", "GPAM", "GPR89B", "HINT2", "HMOX1", "HSD17B12", "HTRA2", "ILVBL", "IPO11", "IPO9", "KDELR1", "KDELR3", "KDSR", "KIAA1468", "KPNA2", "LDAH", "LETM1", "LRRC8C", "LSS", "LTA4H", "MBOAT7", "MFSD10", "MFSD8", "MIA3", "MPC2", "MSMO1", "MTCH1", "MTCH2", "MTFP1", "MTX1", "MTX2", "MYH10", "MYH9", "NAP1L1", "NASP", "NCEH1", "ND1", "NDC1", "NDUFA11", "NDUFA13", "NDUFA7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFS2", "NDUFS6", "NECAP1", "NPC1", "NPC2", "NT5C3B", "NUP107", "NUP54", "NUP93", "OGT", "OPA1", "OPA3", "OSBPL6", "PAFAH1B3", "PAWR", "PCBP2", "PDCD5", "PDCL3", "PEX14", "PHF10", "PLA2G15", "PLBD2", "PMAIP1", "PNPLA6", "POFUT2", "PPT1", "PRAF2", "PSAP", "PTGES2", "PUF60", "RAB11FIP1", "RAB24", "RAB2A", "RAPGEF2", "RINT1", "RNASET2", "RTN3", "RTN4", "SCAMP2", "SEC22B", "SEC63", "SEH1L", "SFXN2", "SFXN4", "SGPL1", "SIGMAR1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A40", "SLC25A42", "SLC25A44", "SLC33A1", "SLC35B2", "SLC35F2", "SLC4A7", "SLC7A1", "SLIT2", "SNX2", "SNX9", "SPNS1", "SPTLC1", "SRSF7", "STAG2", "STIM1", "STX10", "STX18", "STX3", "STX6", "STX8", "SYS1", "TAP1", "TIGAR", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TK1", "TM7SF2", "TMED2", "TMED7", "TMED9", "TMEM14C", "TMX1", "TMX4", "TOMM20", "TOMM22", "TOMM5", "TRAM1", "TTC19", "TTYH3", "TUBB2B", "UBIAD1", "UNC119", "UNC119B", "UQCR10", "UQCRC2", "UQCRQ", "VDAC1", "VDAC2", "VDAC3", "VPS45", "XRCC6", "YIF1A", "YIF1B"]} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/advanced/idx2term.json b/protein_atlas_disease_involvement/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/protein_atlas_disease_involvement/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/basic/idx2term.json b/protein_atlas_disease_involvement/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..04574cd64353dd3eef208723b70a65eb65bb482a --- /dev/null +++ b/protein_atlas_disease_involvement/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Primary mitochondrial disease", "1": "Neurodegeneration", "2": "Cataract", "3": "Congenital disorder of glycosylation", "4": "Epilepsy"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/basic/plot_0.png b/protein_atlas_disease_involvement/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..961c338982a4e90442e9ef8aeb3a2d324487a9b0 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:330cae45877c0e7c8fd051c9e85adb9c26f52dc5deaa903d8e3f0cb9a9a4044e +size 144258 diff --git a/protein_atlas_disease_involvement/basic/plot_1.png b/protein_atlas_disease_involvement/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..f4920ca3e8226a3a3e2bd4cbd5bf217037fadafc --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid 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file mode 100644 index 0000000000000000000000000000000000000000..339104860b6738ef6a88c0473f08ec694717b93d --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Amyotrophic lateral sclerosis 0 12 2.145745353240312 0.0318933006381954 3.0533980582524274 13.87864077669903 0.4936496443371127 0.508408134121438 2.1804655926597256 1.4762949218233254 0.8513354672584855 0.3027847309213633 0.4276775695775323 0.1430638950507344 0.2685353106225043 0.544318157098314 0.7970946997430631 +Neuronal ceroid lipofuscinosis 3 5 2.1001160816008184 0.0357186309977126 2.1941747572815533 3.616504854368932 0.8145003765175237 0.1716854616439567 0.950812145720796 0.8293870806734848 1.6764073513361384 0.2241811956153294 0.0009918498188417 0.0014481500629001 0.0001833288791406 0.000142755965642 0.0019884945269669 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..696f481237324672bd76bf8f232bef805efa8483 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 114, + "title": "Average number of proteins per term", + "value": 21.403508771929825 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2e87f637b241a5c5c023f4b4c400165dd49d29c6 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..90c5ec43d332c837f9b95d0876a6042ceee6948c --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,33 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Neuronal ceroid lipofuscinosis 0.8676392623671205 2.1001160816008184 0.0357186309977126 0.984179127171612 0.5089904917174055 5 Q8NHS3,P50897,O75503 3 +Primary mitochondrial disease 0.4714698071045753 1.858490396881636 0.0630994058495042 0.999406991883516 0.5237333411950568 104 P00846,P00403,Q9NPL8,Q9BQP7,O95831,Q70HW3,P03886,Q9Y584,O75880,Q9HA77,Q8NFF5,Q7KZN9,O43676,O14949,Q9Y2R0,Q9BQT8,Q9UBX3,Q53H12,Q5XKP0,P13073,P22695,O75380,P20674,Q6DKK2,Q86Y39,Q96RR1,Q96IX5,Q6P4A7,Q96CU9,O43819,Q9UMS0,Q9Y375,Q9P0J0,Q8TB37 34 +Leber hereditary optic neuropathy 0.993540051679586 1.802626880940261 0.0714468324577954 0.9997862173557306 0.5237333411950568 2 P00846 1 +Retinitis pigmentosa 0.5698046192492653 1.7514855787344128 0.0798623032490908 0.9999242780343356 0.5237333411950568 15 P00846 1 +Diabetes mellitus 0.6595597676944064 1.675545466037362 0.0938272582996795 0.9999867549581596 0.5237333411950568 9 P03886,P31751 2 +Mucopolysaccharidosis 0.8231880353784657 1.6504498753346752 0.0988509572779607 0.9999929722657716 0.5237333411950568 4 P16278 1 +Leigh syndrome 0.6315921473193423 1.628275319866164 0.1034665202036346 0.9999960863462048 0.5237333411950568 10 P00846,Q7KZN9 2 +Ehlers-Danlos syndrome 0.881719805173433 1.2791417604556654 0.2008471401612248 0.9999999999920604 0.6536383695889255 3 Q8NCH0 1 +Dystroglycanopathy 0.859173126614988 1.268153890844036 0.2047429995231515 0.9999999999954516 0.6536383695889255 2 O43505 1 +Corneal dystrophy 0.8562661498708029 1.2566380895814422 0.2088847156468452 0.999999999997492 0.6536383695889255 2 Q9NR56 1 +Niemann-Pick disease 0.8540051679586416 1.2476867741628248 0.212145786620967 0.999999999998434 0.6536383695889255 2 O15118 1 +Neurodegeneration 0.3658259426785836 1.1396741629656078 0.2544220751236448 0.9999999999999972 0.7305986312784034 134 Q99720,Q14108,Q9BRK0,P07196,O95831,P03886,P50897,P06865,Q8NHS3,Q13510,Q9NSD9,O75503,O14653,O75298,P49902,P54802,Q10713,O14773,Q8IY17 19 +Gangliosidosis 0.6191174463200049 1.0580393547738864 0.2900375007839599 1.0 0.7519791982267806 5 P07602,P16278 2 +Cone-rod dystrophy 0.7871447028423599 0.9863142334890412 0.3239789372871087 1.0 0.7630575610702056 2 Q13432 1 +Cataract 0.4103655747813102 0.9473947531262156 0.3434376637532645 1.0 0.7630575610702056 25 P48449,P08670,Q15800,Q9H6K4,Q53H12 5 +Congenital disorder of glycosylation 0.4001427666572396 0.895595850391355 0.3704686527542744 1.0 0.7678804802543143 26 Q9UP83,Q9BT22,Q9BV10,Q96AA3,P51571,Q9HC07,P83436,O75787,O60762,Q9H553,P46977,Q8N511 12 +Hereditary spastic paraplegia 0.3993935343108189 0.7614232151269317 0.4464043256260606 1.0 0.8185962835876981 19 Q9BRK0,P49902,Q8IY17,O75298 4 +Leukodystrophy 0.4004731429199129 0.6200093252367765 0.5352516475189597 1.0 0.8767447323097681 14 Q9NR50,P07602 2 +Ciliopathy 0.4542632438810792 0.6055423295663326 0.5448187079028328 1.0 0.8767447323097681 8 Q96J42,Q9UBB4,Q9NVR5,Q86Y56 4 +Epilepsy 0.3666030418940439 0.603700514704092 0.5460427718771363 1.0 0.8767447323097681 63 Q9Y4G8,Q14108,P16615,Q96F07,Q92643,Q13510,O75503,Q8NC96,O75787,P57740,P03886,Q03252,O14653,O14773 14 +Congenital myasthenic syndrome 0.6778675282714137 0.571680629649293 0.5675383596848027 1.0 0.8844915724755306 3 Q4J6C6,Q9H553 2 +Rhizomelic chondrodysplasia punctata 0.6427648578811216 0.4773199003336576 0.6331343423047038 1.0 0.9497015134570556 2 O00116 1 +Spinocerebellar ataxia 0.4147323933478407 0.4283486484166789 0.6683973052936096 1.0 0.9617949895177188 8 O14773 1 +Congenital muscular dystrophy 0.4605653503526657 0.2922767475664244 0.7700750357544426 1.0 1.0 4 O43505 1 +Alport syndrome 0.4974160206718395 0.1476028881804299 0.8826561756322882 1.0 1.0 2 P35579 1 +Cardiomyopathy 0.3009391156426762 0.138402150454578 0.8899225975566485 1.0 1.0 23 P00846,Q53H12,O43819 3 +Progressive external ophthalmoplegia 0.3582486576422853 0.1190926176265517 0.9052019794000892 1.0 1.0 5 Q9BQP7 1 +Tumor suppressor 0.2953032730323978 0.1159011451315184 0.907730888130244 1.0 1.0 25 Q9H307 1 +Emery-Dreifuss muscular dystrophy 0.3399118362536645 0.0818004208242445 0.9348054214280046 1.0 1.0 5 P50402 1 +Glaucoma 0.3572351421188577 0.0516645554407622 0.9587959801634643 1.0 1.0 2 Q9UM00 1 +Aicardi-Goutieres syndrome 0.3644588045234194 0.0292030013926472 0.9767026874908136 1.0 1.0 3 Q9Y3Z3,P55265 2 +Osteogenesis imperfecta 0.2931770910089887 0.0108245795631843 0.9913634037502046 1.0 1.0 8 O75718 1 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ac5456442056d9049edf90115d908fc7ffce4dc8 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atherosclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital dyserythropoietic anemia", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Corneal dystrophy", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AARS", "AARS2", "ABAT", "ABCB1", "ABCB7", "ABCC1", "ABCD4", "ABHD12", "ABI1", "ACAA1", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADAR", "ADD3", "ADK", "ADNP", "ADSL", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AKAP12", "AKR1B1", "AKT2", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANO10", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA7", "AP1B1", "AP1S2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APEX1", "APOB", "APRT", "ARCN1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL2", "ARL3", "ARL6IP1", "ASAH1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATIC", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP7A", "ATP7B", "ATRX", "ATXN10", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BAG3", "BANF1", "BARD1", "BAX", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCKDHA", "BCKDHB", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BMI1", "BMS1", "BPTF", "BRCA1", "BRD3", "BRD4", "BRI3BP", "BUB1B", "BUD23", "C19orf70", "C1QBP", "C3orf58", "CAD", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBX2", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC6", "CCNB1", "CCT5", "CDC16", "CDC27", "CDC34", "CDC37", "CDC42", "CDC73", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDKAL1", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHEK1", "CHP1", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COL4A3BP", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COQ9", "COX15", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRK", "CRTAP", "CSDE1", "CSE1L", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DBN1", "DBT", "DCPS", "DCTN1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIAPH1", "DIS3", "DKC1", "DLD", "DLST", "DNAAF2", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC13", "DNAJC19", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOLK", "DPF2", "DPM1", "DSC3", "DSG2", "DSP", "DST", "DYNC1H1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EHHADH", "EHMT1", "EI24", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF5A", "ELAC2", "ELL", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "ENO1", "EPB41", "EPB41L3", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ESCO2", "ETFA", "ETFB", "ETFDH", "EXOC6B", "EXOC8", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EZR", "FADS2", "FAF1", "FAM120A", "FAM3C", "FANCD2", "FANCI", "FAR1", "FARS2", "FARSB", "FASN", "FASTKD2", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GALK1", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GCDH", "GCLC", "GDAP1", "GEMIN4", "GFM1", "GFM2", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLS", "GLUD1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNPAT", "GNS", "GOLGA5", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPI", "GPT2", "GRB2", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2I", "GTPBP3", "GUF1", "GYG1", "GYS1", "H4C1*", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HK2", "HLA-A", "HMGA1", "HMGB3", "HMGCL", "HMGXB4", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOXD11", "HPRT1", "HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IFT81", "IGBP1", "IGF2R", "ILF3", "ILK", "IMPAD1", "IMPDH2", "INTS1", "INTS8", "IPO7", "IRF2BPL", "IRS4", "ITGAV", "ITGB1", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KIDINS220", "KIF11", "KIF1A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KMT2A", "KMT2B", "KTN1", "L2HGDH", "LAMB1", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETMD1", "LGALS3BP", "LGMN", "LIN9", "LIPA", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPPRC", "LSS", "LTA4H", "LYN", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN2B1", "MAP4", "MAPK1", "MARS", "MARS2", "MATR3", "MBD1", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED12", "MED17", "MED23", "MED25", "MESD", "MFN2", "MFSD8", "MGME1", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MMAB", "MOCS1", "MOGS", "MORC2", "MPDU1", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MYH10", "MYH9", "MYO6", "NAA15", "NAGLU", "NAMPT", "NANS", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG2", "NCAPH", "NCKIPSD", "NCOR1", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEFL", "NEK9", "NEPRO", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NISCH", "NME1", "NNT", "NONO", "NOP10", "NOP56", "NPC1", "NPC2", "NPM1", "NR2F2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSMCE2", "NSMCE3", "NSUN2", "NSUN3", "NSUN5", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OCLN", "OGDH", "OGT", "OPA1", "OPA3", "ORC6", "OXCT1", "P3H1", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCNA", "PDCD4", "PDHA1", "PDHB", "PDK1", "PDK3", "PEPD", "PEX11B", "PEX14", "PEX19", "PEX3", "PFKM", "PFN1", "PGK1", "PGM1", "PHB", "PHF6", "PHGDH", "PHIP", "PI4KA", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIN1", "PINX1", "PISD", "PKM", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNN", "PNP", "PNPLA4", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP2R1A", "PPP2R5D", "PPP5C", "PPP6C", "PPT1", "PQBP1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PTDSS1", "PTRH2", "PUF60", "PURA", "PUS1", "PYCR1", "PYCR2", "PYGL", "QARS", "QKI", "QRSL1", "RAB10", "RAB11B", "RAB18", "RAB3GAP2", "RAB7A", "RAB8A", "RABL3", "RAC1", "RAD21", "RAD23B", "RAD51C", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM15", "RBM28", "RBM6", "RBMX", "RBPJ", "RDH11", "RDX", "REEP2", "REPS1", "RFC1", "RFC2", "RFT1", "RHOA", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNASET2", "RNPC3", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS29", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RRM1", "RRM2", "RSBN1L", "RSPRY1", "RSRC1", "RTN2", "SAMHD1", "SAR1B", "SARS", "SART1", "SBDS", "SC5D", "SCARB2", "SCO1", "SCO2", "SCRIB", "SDHA", "SDHB", "SDHC", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC63", "SEPT2", "SEPT9", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SIGMAR1", "SIN3A", "SKIV2L", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC33A1", "SLC35A3", "SLC3A2", "SLC44A1", "SLC5A6", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMYD3", "SND1", "SNRNP200", "SNRPE", "SNX3", "SOAT1", "SOD2", "SON", "SORD", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPOP", "SPR", "SPTAN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRP54", "SRP72", "SRSF3", "SSB", "SSR4", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STMN1", "STRAP", "STRN", "STT3A", "STT3B", "STUB1", "STX5", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D4", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCEA1", "TCF20", "TCOF1", "TECR", "TELO2", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIMM17A", "TIMM22", "TIMM50", "TIMMDC1", "TK1", "TKT", "TMCO1", "TMEM126B", "TMEM165", "TMEM199", "TMEM230", "TMEM43", "TMEM70", "TMF1", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TPX2", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSG101", "TTC19", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUFM", "TWNK", "TXLNA", "TXNDC15", "TXNRD1", "TYMS", "U2AF1", "UBA1", "UBAP1", "UBE2N", "UBE3A", "UBIAD1", "UBQLN4", "UBR5", "UBTF", "UFC1", "UFSP2", "UMPS", "UNC119", "UPF3B", "UQCRB", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP9X", "UTP4", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VKORC1L1", "VPS13A", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WBP2", "WDR1", "WDR26", "WDR36", "WDR5", "WFS1", "WIPI2", "XPNPEP3", "XPO1", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZC3H14", "ZCCHC8", "ZEB2", "ZMPSTE24", "ZMYM2", "ZNF148", "ZNF644"], "leading_proteins": ["ADAR", "AGK", "AGPS", "AIFM1", "AKT2", "ALG1", "ALG12", "ALG2", "ASAH1", "ATP2A2", "ATP6", "ATP6AP2", "ATXN10", "B4GAT1", "C19orf70", "CARS2", "CHST14", "CLN5", "COA3", "COG5", "COG7", "COX15", "COX2", "COX4I1", "COX5A", "CRTAP", "CYFIP2", "DNAAF2", "DNAAF5", "DPM1", "EIF2B3", "EMD", "FARSB", "FLAD1", "FOXRED1", "GLB1", "GOSR2", "HEXA", "LMNB2", "LSS", "MBNL1", "MFSD8", "MGME1", "MSMO1", "MYH9", "NAGLU", "ND1", 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1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 0.0292740292610029 0.0067395360058667 0.0029276643552459 0.018618787305556 0.1575835672195456 +Glycosidase 6 19 2.8043713078856483 0.0050414809078425 7.798543689320389 18.135922330097088 0.5112745472223946 0.1951515073440806 2.9064203812520417 1.9684331341643595 1.9501681029822375 0.2619382904734375 7.731055035883707e-06 1.0 0.0082729445560879 6.880235330436636e-05 0.0042906431799932 +Metalloprotease 9 25 2.4261750236706705 0.0152589093987085 8.160194174757281 26.429611650485437 1.390302281711237 0.2661274848815638 3.192614043118206 1.543038499308978 1.1108461579919544 0.309446154241223 0.0176600324030677 1.0 0.0186371594327644 0.000471503205235 0.0004229506315236 +Host cell receptor for virus entry 2 18 2.3740808621562297 0.0175926972241349 4.509708737864078 15.157766990291265 0.7214109752050332 0.2527966464979699 2.499010078306418 1.9009100692398744 1.5211756979359785 0.2791170769282048 0.0355040413058726 0.0172375696548913 0.0077496201950681 0.0808776862517318 0.1451121707049519 +Translocase 13 27 2.2411182998024795 0.0250184131257678 8.031553398058252 23.23543689320388 0.8266305625937611 0.3429767730570308 3.903132239147793 3.2553774114037415 1.2917497354360188 0.3272657999875639 0.0005618007096964 0.2516504230112798 0.0002790172713656 0.0031898046957766 0.0001244263791846 +Carboxypeptidase 3 6 2.004172854870473 0.0450515472998405 3.1359223300970873 6.150485436893204 0.9957728306848488 0.1212034427500092 1.2071674596015187 0.4479454254223922 1.8250051834990677 0.2074401112551974 0.0268439946301445 0.0022827689145391 0.0090253131212995 0.0051503840765812 0.0005289198821125 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..bdad4f13ca1126be405f5c79b81c4e12207c818e --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 97, + "title": "Average number of proteins per term", + "value": 37.402061855670105 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a75ae09262bc38053675d43706f81a4bb3c4bb66 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3bd7662f64f169f71170fc5139d2f2ab068c3e66 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,25 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Receptor 0.6653063275834716 3.253872168501573 0.0011384349527419 0.1046056970929255 0.0779110275887061 43 Q99720,O15173,Q14108,P24390,P30825,Q8WTV0,Q9UBG0,Q15758,Q9Y5M8,Q9NS69,O75787,Q5KU26,O15118,O43731,Q8WU17 15 +Glycosidase 0.7102060506260898 2.8043713078856483 0.0050414809078425 0.3875331794596879 0.0815039413434539 19 P16278,P06280,O60476,Q9BTY2,P54802,O60502 6 +Metalloprotease 0.6108141532644945 2.4261750236706705 0.0152589093987085 0.7749702989194766 0.1539626365179734 25 O75844,Q9UIQ6,Q9NZ08,P55786,O43847,Q96TA2,P42892,Q7Z2K6,O75976 9 +Host cell receptor for virus entry 0.6444330803287781 2.3740808621562297 0.0175926972241349 0.8212345981501119 0.1539626365179734 18 Q14108,Q8WTV0 2 +Translocase 0.5701405425116025 2.2411182998024795 0.0250184131257678 0.9143648339385348 0.1617857382132984 27 Q03518,P16615,O75306,P98194,P06576,Q9HD20,P00403,P35670,P08183,P20020,P03886,P33527,Q13423 13 +Carboxypeptidase 0.8036451809377619 2.004172854870473 0.0450515472998405 0.9885698179083282 0.2185000044042264 6 P42785,Q9HB40,Q9H3G5 3 +Transducer 0.7363491310666698 1.7981803388741548 0.0721484341997746 0.9992994889617682 0.2591550710830732 7 P63218,Q14344,P04899,P02786 4 +Porin 0.8580004960648473 1.7872516714487563 0.0738968212940629 0.999416609489258 0.2591550710830732 4 P21796 1 +Guanine-nucleotide releasing factor 0.6001873517395728 1.7402627830976989 0.0818128858589277 0.9997462968983728 0.2645283309438664 13 Q9Y4G8,Q02818,P80303,Q5VZ89,Q9Y4F1,A4D1U4 6 +Muscle protein 0.7279321184894101 1.6791699857718894 0.0931189196902959 0.9999237248389736 0.2822667253112096 6 P14649,P60660,Q03001,P67936 4 +Monooxygenase 0.9050080775444282 1.3639812553841004 0.1725734652426722 0.999999989534594 0.458007672859698 3 Q6UW02,Q16850 2 +Ion channel 0.5789695912725563 1.357243170869581 0.1747039576887508 0.9999999918501998 0.458007672859698 10 Q8TDW0,Q9C0H2,P0CG08 3 +Cytokine 0.6948693747616357 1.138655756019781 0.2548467632695776 0.9999999999995948 0.5302374512571716 4 P43490 1 +Threonine protease 0.8232633279483152 1.0674994117636378 0.285746379130372 0.9999999999999932 0.5302374512571716 3 P28074,P28072 2 +Aminopeptidase 0.5215164976122744 1.0565579211434122 0.290713393270869 0.9999999999999966 0.5302374512571716 10 P55786,Q9UIQ6 2 +Protease 0.400772881931697 0.915561395997174 0.3598969867300747 1.0 0.6347274129603137 74 P42785,Q96K76,P67812,Q9HB40,Q16740,Q9UIQ6,Q99436,Q92643,O43464,O75976,Q9H3G5,P28072,Q4J6C6,Q9NZ08,P55786,O43847,P09960,Q9NUQ7,P42892,Q7Z2K6,O00303,O75844,P28074,P10619,Q96TA2,O14773 26 +Voltage-gated channel 0.6115165114572814 0.810193494743918 0.4178289757160884 1.0 0.6891894776025209 4 P0CG08 1 +Glycosyltransferase 0.3585455353543038 0.724016195670682 0.4690557921722296 1.0 0.7109126850110354 36 P43490,Q9BT22,Q06203,O15294,Q13126,O60762,P46977,O43505,Q86SF2 9 +Tyrosine-protein kinase 0.4686287192755437 0.5385279660996415 0.5902126032241197 1.0 0.7387413667145236 6 P19525,Q9UIG0,P07947,P07948,Q15375 5 +Oxidoreductase 0.2708673572327841 0.3877561292375625 0.698196514036884 1.0 0.8259153885558261 174 P30519,O15254,O95831,P50336,Q6UW02,P78417,Q53GQ0,Q9BU89,Q15392,Q99536,Q16850,Q8N0U8,P13073,Q6YN16,Q8NBM8,P09601,Q15800,Q8N4Q0,P51648,O76062,Q14534,P16435,Q9HBH5,Q9UHG3,Q8IXB1,Q8NBX0,Q9H6W3,P30837,Q06136 29 +Heparin-binding 0.3729768723097645 0.1911694918259385 0.8483928047871356 1.0 0.9143789118261352 6 O94813 1 +Acyltransferase 0.2818645458612566 0.0652060874181564 0.9480099143874264 1.0 0.9887845343610792 38 Q9BWD1,Q9HCL2,P23786,Q8NCC3,P50416,Q99943,O15269 7 +Initiation factor 0.2765493616560895 0.0513750140403117 0.9590266943815072 1.0 0.9896339293085764 30 P55010 1 +Endonuclease 0.2764500255531176 0.0241690854704158 0.9807177371446218 1.0 1.0 17 O00584,Q9UQ84 2 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2ad9df464ece283705dadf514227463da8cee75d --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA replication inhibitor", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgG-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCC1", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ANLN", "ANO6", "ANP32B", "ANXA1", "ANXA2", "APBB1", "APEH", "APEX1", "APLP2", "APOB", "APRT", "AQR", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL8B", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7A", "ATP7B", "ATRX", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BANF1", "BAP18", "BARD1", "BAZ1B", "BCAT2", "BCKDHA", "BCKDHB", "BCLAF1", "BCOR", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "CAD", "CALR", "CAMK2G", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX2", "CBX3", "CBX8", "CCAR1", "CCAR2", "CCDC47", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC34", "CDC37", "CDC42", "CDC5L", "CDCA7L", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPU", "CEPT1", "CERS1", "CERS2", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT9", "CNP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPS5", "COQ8A", "CORO1C", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRYZ", "CS", "CSDE1", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CUL5", "CXADR", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCPS", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLK", "DOLPP1", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPRS", "ERAL1", "ERAP1", "ERCC3", "ERCC6L", "ERMP1", "ERO1A", "ERO1B", "ERP44", "ESCO2", "ESD", "ETFDH", "EXD2", "EXO1", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "F11R", "FADS2", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLYWCH1", "FMR1", "FN3KRP", "FOXK1", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDE1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GGCT", "GGCX", "GGH", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPI", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPAD1", "IMPDH2", "INA", "ING5", "INTS11", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "KARS", "KAT7", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIAA1147", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KRR1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPAP1", "LRPPRC", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L3", "LYAR", "LYN", "LYPLA1", "M6PR", "MACF1", "MAEA", "MAGED2", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAPK1", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MATR3", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFN1", "MFN2", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOCS1", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MYBBP1A", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCAM1", "NCBP2", "NCBP3", "NCEH1", "NCL", "NCOA5", "NCOR1", "ND1", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NEPRO", "NES", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NKRF", "NKTR", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUCB1", "NUCB2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NUSAP1", "NXF1", "NXN", "OAT", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC6", "OTUB1", "OXCT1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PEBP1", "PECR", "PEDS1", "PELO", "PELP1", "PEPD", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB2", "PHC2", "PHF2", "PHF5A", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PIAS1", "PIGG", "PIGK", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP5C", "PPP6C", "PPT1", "PPT2", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKCA", "PRKCB", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRSS3", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "RAB10", "RAB11B", "RAB18", "RAB1A", "RAB1B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAI1", "RALA", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC3", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOX1", "RIPK1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPEP", "RNPS1", "ROMO1", "RP2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP14", "RPP30", "RPP38", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RREB1", "RRM1", "RRM2", "RRP1B", "RRP7A", "RRP8", "RRP9", "RSBN1", "RSBN1L", "RSF1", "RTCB", "RTF1", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARNP", "SARS", "SARS2", "SART3", "SC5D", "SCAF1", "SCAF8", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SENP3", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A2", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMYD3", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAT1", "STAT3", "STAU1", "STAU2", "STK26", "STMN1", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRKH", "TECR", "TERF2", "TERF2IP", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TLE3", "TM7SF2", "TMCO1", "TMEM109", "TMEM126B", "TMF1", "TMOD1", "TMOD3", "TMPPE", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TST", "TTF1", "TTYH3", "TUFM", "TWNK", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBIAD1", "UBN1", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF3B", "UROD", "USP10", "USP14", "USP19", "USP36", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP3", "UTRN", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VRK1", "VRK2", "WARS", "WARS2", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR5", "WRNIP1", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "ZADH2", "ZC3H13", "ZC3H14", "ZC3H8", "ZC3HAV1", "ZCCHC17", "ZCCHC3", "ZDHHC20", "ZEB2", "ZFR", "ZMPSTE24", "ZNF148", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZRANB2"], "leading_proteins": ["ABCB1", "ABCC1", "ACAT2", "ACOX3", "AGPAT1", "AIFM1", "ALDH1B1", "ALDH3A2", "ALG1", "ATP13A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP6AP2", "ATP7B", "B4GAT1", "BAZ1B", "CLPP", "COLEC12", "COX2", "COX4I1", "CPD", "CPT1A", "CPT2", "CPVL", "CTSA", "CYP20A1", "CYP51A1", "DENND4C", "DHCR24", "DNAJC10", "DOHH", "DPM1", "DST", "ECE1", "EIF2AK2", "EIF3F", "EIF5", "EPHA7", "ERAP1", "ERMP1", "EXO1", "FARP1", "FUCA2", "GALNT7", "GLA", "GLB1", "GNA13", "GNAI2", "GNG5", "GPAM", "GPR89B", "GSTO1", "HMOX1", "HMOX2", "HSD17B12", "HSDL2", "HTRA2", "KDELR1", "KDELR3", "KDSR", "KIAA1147", "LNPEP", "LRRC8C", "LTA4H", "LYN", "MAN1A2", "MGEA5", "MRC2", "MSMO1", "MTAP", "MYL6", "MYL6B", "NAGLU", "NAMPT", "ND1", "NDUFS2", "NNT", "NPC1", "NPEPPS", "NRDC", "NUCB1", "NUCB2", "OGT", "PCYOX1", "PCYOX1L", "PGRMC2", "PIGK", "PLA2G15", "POR", "PPAT", "PPOX", "PRCP", "PREPL", "PSMB5", "PSMB6", "PSMB7", "RAPGEF2", "RDH14", "RIOX1", "RNASET2", "RNF139", "SCARB1", "SCARB2", "SCCPDH", "SCPEP1", "SEC11A", "SIGMAR1", "SLC1A5", "SLC7A1", "SLIT2", "SPTLC1", "SQLE", "SRPRB", "STT3A", "TAP1", "TFRC", "TM7SF2", "TOMM22", "TPM4", "TPP1", "TTYH3", "UFSP2", "USP47", "VAT1", "VDAC1", "VKORC1L1", "YES1", "YME1L1", "ZADH2", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/idx2term.json b/protein_atlas_protein_class/advanced/idx2term.json new file mode 100644 index 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-0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 252 626 5.019313447888714 5.185647658287779e-07 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 2.1033184273311505e-23 4.2508318356866075e-10 2.9796242481244755e-16 6.852514806509706e-29 1.2781371011591262e-38 +Transporters 122 391 2.525215427196114 0.0115627384911189 108.9004854368932 367.3009708737864 1.469396346451591 0.4764419032567517 40.40141182476491 35.10022679965902 2.352674986871393 0.4490473364946538 1.3519749328403045e-07 3.97196579018323e-06 6.856634293367611e-06 2.53797120974914e-09 1.665899201328637e-17 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9c78dff5eaeca6446accce378c45087006f13eca --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 21, + "title": "Average number of proteins per term", + "value": 475.76190476190476 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..555b9eebcaa0a32c5626bc5725224d56a062d35f --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5239180f802d1dd823fa459f581d32e242cc857d --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,9 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.5782023095778543 5.019313447888714 5.185647658287779e-07 1.0889803611633364e-05 5.444930041212668e-06 626 P00846,Q99720,P30519,Q14108,Q9H6V9,P02786,Q99595,O75306,O60830,Q5VW38,O14678,Q4KMQ2,Q9HCL2,O60637,Q5VZ89,Q567V2,P35670,Q70HW3,Q3B7T1,P03886,Q5BJF2,Q9Y584,Q9Y487,O75448,O43169,Q9NZJ7,Q9C0H2,Q6NUM9,Q16799,Q8N511,O43676,O94901,Q9NPR9,O43808,P24390,O14925,Q9H061,Q8WTV0,Q93050,Q9BXP2,Q8NHS3,Q9UDX5,O95197,Q9NS69,Q96A57,Q92643,O75964,Q86XL3,Q8NCC3,Q5W0Z9,O15118,Q9H6K4,Q16850,Q8N0U8,O43731,Q8IXU6,Q13423,Q13505,O43772,Q8WVI0,Q8WY22,Q92896,P98194,P09601,Q9HD20,O60476,P08183,Q5KU26,Q86YN1,Q9UDW1,P42892,Q9Y282,Q96CP7,O75844,P43307,Q07065,Q6P4A7,Q9P2W9,Q9NR77,P11117,Q9BSK2,Q9P0J0,Q9UI14,Q8NBX0,Q8TBP6,P41440,Q8IY17,Q03518,O15173,Q15047,Q96A26,Q96NB2,O00461,P0CG08,O95831,Q8IZA0,Q8NCH0,Q96GQ5,P27105,Q3SXM5,Q13641,O43760,Q5BJH7,Q7KZN9,Q96G23,Q53GQ0,Q6UW68,Q9UIQ6,P51790,Q9BT22,Q9BTX1,Q9H1E5,P37268,Q9Y2R0,Q15392,O00264,Q9H4I3,O60725,Q9UBX3,P53985,Q96H78,Q8WU17,P13073,Q9NQX7,Q13277,Q6PIU2,Q16625,Q9Y3B3,Q15800,P51648,O76062,O14653,Q7Z2K6,Q9Y6M7,Q9UBV2,P38435,P30825,O75298,O95202,P51571,Q9HC07,Q9Y5M8,Q92575,Q9NX40,O75396,O43819,O60499,Q8IXB1,Q96TA2,P46977,Q9UNK0,O43657,Q06136,Q15070,Q9Y3E0,O43752,P16615,Q00765,Q9H2V7,Q9BRK0,O96005,Q96HV5,Q9P0I2,P00403,Q8N2H4,Q96PC5,Q6UW02,O15127,P67812,Q70UQ0,Q12981,Q13586,Q15363,Q86VD7,P46783,Q5SWX8,Q9H3N1,Q9NQC3,Q9UGP8,Q9Y6K0,Q15388,Q8TB61,Q96A33,Q96EX1,Q9GZM5,Q99943,O75976,Q9Y619,Q9P0S9,O95168,O75381,O94919,P50402,P51572,Q14534,Q15629,P50416,Q9Y6C9,Q9P260,Q9BXS4,P16435,O95249,O95070,P09669,O94813,O75787,Q9Y679,Q5VV42,Q14728,Q96KC8,O95470,O60925,Q9NPL8,Q9HD45,O00400,O75880,P33527,O75915,O75027,O15269,Q9NPA0,O15400,Q92667,Q9UBG0,Q96RQ1,Q15758,Q08722,P10321,Q92804,Q9BSR8,Q15375,P16260,Q9Y5Z9,Q8WWI1,Q8N1F7,Q5JRA6,Q8NHH9,Q96N66,O95563,A1L0T0,P20020,Q96AG4,Q86Y39,Q9BVK6,Q9BV10,Q96IX5,Q6ZRP7,Q05086,Q8IY95,Q8TDW0,Q5SNT2,P04843 252 +Transporters 0.4596261106105795 2.525215427196114 0.0115627384911189 0.2166943033648196 0.0554355632862829 391 Q99720,Q14108,P02786,O14678,Q4KMQ2,Q5VW38,Q9NRR5,O60637,P35670,P57740,P45880,Q70HW3,Q5BJF2,Q9NZJ7,Q9H307,Q16799,O94901,Q9C0H2,O43808,Q8N511,P49458,P24390,Q9BXP2,Q9H061,Q8WTV0,Q93050,Q96A57,Q8NHS3,O15118,Q8IXU6,O43772,Q8WY22,P98194,Q9HD20,P08183,O75844,Q07065,Q6P4A7,Q9NR77,Q9BSK2,Q9UI14,Q8TBP6,P41440,Q03518,O43681,Q96NB2,P07602,P27105,Q6UW68,Q9BTX1,Q9BQT8,Q9UBX3,P53985,Q96H78,P13073,Q13277,Q16625,Q9BRK5,Q9Y3B3,P20674,Q9Y6M7,Q9UBV2,P30825,O95202,Q9HC07,P46977,Q15070,O43752,P16615,Q9H2V7,O96005,Q96HV5,Q9P0I2,P00403,Q96PC5,O15127,Q13586,Q9UJS0,Q15363,Q86VD7,Q9H3N1,Q9UGP8,Q9Y6K0,P14635,Q8TB61,Q96A33,Q9GZM5,Q9Y619,Q96EE3,O75381,P51572,O75746,Q15629,P50416,Q9Y6C9,Q9BXS4,Q9UI26,Q9H2D1,O75787,O75955,O00400,P33527,O75915,O75027,Q9NPA0,Q15758,Q08722,P16260,Q8N1F7,Q5JRA6,P61916,P50570,Q8NHH9,Q96N66,O95563,P20020,Q96AG4,P60602,Q8IY95,Q8TDW0,Q7Z3B4,P04843 122 +Predicted secreted proteins 0.4271574238474521 1.2136847170946072 0.2248681425576784 0.9952478809031856 0.4624555535977087 55 P43490,Q8N128,Q8WUJ1,Q08380,O00584,Q9BTY2,Q9HB40,Q02818,Q9UM22,Q9H6E4,Q8NBM8,Q8NDZ4,O94919,P80303,Q9NZ08,Q9UMX5,Q15165,O94813,O75718,P14174 20 +Candidate cardiovascular disease genes 0.4927282705002775 0.9055979285316772 0.3651487056174609 0.9999282020246928 0.5898556013820523 10 P06865,Q15165 2 +CD markers 0.3895178891903469 0.6861544606758353 0.4926157112297564 0.9999993512500804 0.6657378771406863 18 Q9UBG0,P08183,Q08722,P02786 4 +Human disease related genes 0.265036353100255 0.6744370224490152 0.500033511881391 0.99999952383354 0.6657378771406863 907 Q9H7Z7,P00846,Q99720,Q9Y2D4,Q14108,P52732,O75306,O14678,Q4KMQ2,P35670,P57740,Q70HW3,P15586,P03886,Q9Y584,Q9Y487,Q16740,Q8N511,O43676,P07099,P50897,Q9H061,Q8NHS3,Q86XL3,O15118,Q9H6K4,Q13423,O43772,Q9NSD9,P16278,P98194,P09601,O75503,P08183,Q9NR50,Q9UHX1,P42892,O75844,Q6P4A7,P22830,P06280,Q9NR77,P54802,Q08J23,P11117,Q9P0J0,P49902,Q8IY17,Q03518,P07602,P31751,O00584,O95831,Q8NCH0,Q9HA77,Q7KZN9,Q9BT22,P06865,Q15392,Q13510,Q9BQT8,P33991,Q9UBX3,P53985,Q14145,Q53H12,Q5XKP0,P22695,Q9NR45,Q16625,P35914,P08670,Q15800,P51648,Q6DKK2,O14653,O96000,P38435,O75298,O95202,Q9HC07,Q8NC96,P23786,O43819,Q96TA2,P46977,Q10713,P14174,O14773,Q06136,P16615,Q9BRK0,P07196,P00403,Q9BZK7,Q71SY5,Q16204,Q13586,Q9NWM8,Q9UJS0,P04899,P46783,O14949,Q9UGP8,P49366,Q969T9,P07437,P21964,Q9Y619,O95453,O75381,P50402,P51572,Q96PU5,O00203,O43791,O75746,P50416,P16435,O75787,Q9UMS0,Q5VV42,O75718,P20700,Q9UEY8,Q8TB37,P61457,Q96HY6,Q96F07,Q6NUQ1,P48449,O95470,O15294,Q9NPL8,Q9BQP7,Q8WWY3,P50336,O00400,P04114,O75880,O43505,P33527,O75027,O15269,Q9UP83,P10321,Q9NVI7,Q9BVA1,O60762,Q32P28,Q03252,Q9Y5Z9,Q9BXW9,Q8N1F7,P78318,P61916,P50570,Q4J6C6,Q6PGP7,Q96N66,P61978,Q96B26,Q9NVR5,Q9NUQ7,Q86Y39,O00303,Q8N3U4,Q9UBB4,Q9BV10,Q96RR1,Q96IX5,Q96CU9,Q05086,P83436,P10619,O75648,Q9Y375,Q8TDW0,O75380 179 +Disease related genes 0.2462439401671735 0.210059175140995 0.8336214880858532 1.0 0.9725584027668288 1004 P00846,Q99720,Q9Y2D4,Q14108,P52732,P02786,O75306,O14678,Q4KMQ2,Q9NRW7,Q9NRR5,P35670,P57740,Q70HW3,P15586,P03886,Q9Y584,Q9Y487,Q16740,Q8N511,O43676,P07099,P50897,Q9H061,Q8NHS3,Q86XL3,O15118,Q9H6K4,Q13423,O43772,Q9NSD9,P16278,P98194,Q8NDZ4,P09601,O75503,P08183,Q9NR50,Q9UHX1,P42892,O75844,Q9UNW1,Q6P4A7,P22830,P06280,Q13126,P54802,Q08J23,P11117,Q9P0J0,P49902,Q8IY17,Q03518,P07602,P31751,O00584,O95831,Q8NCH0,Q9HA77,Q7KZN9,Q9BT22,P06865,P37268,Q9Y2R0,Q15392,Q13510,Q9BQT8,P33991,P53985,Q53H12,Q5XKP0,Q8WU17,P13073,P22695,Q9NR45,Q16625,P35914,Q13432,P08670,Q15800,P51648,P20674,Q6DKK2,O14653,P38435,O75298,Q9HC07,Q8NC96,P23786,O43819,Q96TA2,P46977,Q10713,P14174,O14773,Q06136,P16615,Q9BRK0,P07196,P00403,Q96PC5,Q9BZK7,Q71SY5,Q16204,Q13586,Q8NFF5,Q9NWM8,Q9UJS0,Q86VD7,P46783,O14949,Q9UGP8,P28070,P49366,Q969T9,Q96A33,P07437,P21964,Q9Y619,O95453,O75381,P50402,P51572,Q96PU5,O00203,O43791,O75746,P50416,P16435,Q9BUK6,Q9NR56,Q9H2D1,O75787,Q9UMS0,Q5VV42,O75718,P20700,Q9UEY8,Q8TB37,P61457,Q96HY6,Q96F07,Q6NUQ1,P48449,O95470,O15294,Q9NPL8,Q9BQP7,Q8WWY3,P50336,O00400,P04114,O75880,O43505,P33527,O75027,O15269,Q9UP83,P10321,Q92804,Q9NVI7,Q9BVA1,O60762,Q32P28,Q03252,Q9Y5Z9,Q9BXW9,Q8N1F7,P78318,P61916,P50570,Q4J6C6,Q6PGP7,Q96N66,P61978,Q96B26,Q9NVR5,Q9NUQ7,Q86Y39,O00303,Q8N3U4,Q9UBB4,Q9BV10,Q9BUF5,Q96RR1,Q96IX5,Q96CU9,Q05086,P83436,P10619,P00390,O75648,Q9Y375,O75380 194 +Metabolic proteins 0.2647277841743021 0.1032028273864268 0.917801995966385 1.0 1.0 875 Q9H7Z7,P00846,P30519,Q9NPH0,Q9UMR5,Q9HCL2,Q70HW3,P03886,Q9Y487,P78417,O43676,P07099,P50897,Q8WTV0,Q93050,O75964,Q8NCC3,Q9BRR6,O15118,Q969T7,Q16850,Q13423,O43772,Q9NSD9,P16278,P98194,P09601,P55786,O60476,P08183,O60502,Q8N4Q0,Q86YN1,Q9UDW1,O75844,Q15165,Q13011,Q9UNW1,P22830,P06280,Q13126,P54802,Q9UHG3,P11117,Q9P0J0,Q8NBX0,P49902,P41440,Q8IY17,P43490,Q9BWD1,O15254,Q15047,P07602,P31751,Q9BTY2,Q8NCH0,Q96K76,Q96G23,Q53GQ0,Q9BT22,Q9BTX1,P06865,P37268,Q15392,Q13510,Q9BQT8,O60725,Q9UBX3,P53985,Q53H12,Q8WU17,P13073,P22695,Q9NR45,P35914,Q15800,P51648,P20674,O76062,Q99956,O96000,Q9Y6M7,P30825,O14976,P23786,P49005,P46977,Q10713,P14174,O14773,P30837,Q06136,P16615,P00403,Q9BZK7,P67812,O14734,Q8NFF5,Q9NWM8,Q9UJS0,Q86VD7,O14949,Q9Y6K0,Q9H773,P49366,Q8TB61,Q9H7B4,Q9NQ88,Q99943,P21964,Q9Y619,Q96EE3,O95168,P51572,Q96PU5,O95302,O75746,Q14534,P50416,Q8TBX8,P16435,Q9H2D1,P06576,P09669,Q9HBH5,O94923,P61457,P48449,O95470,O15294,P50336,O00400,P04114,O43505,P33527,O15269,P83916,Q9BV57,Q15758,Q06203,O60762,Q15375,Q15102,P16260,Q86SF2,Q9Y5Z9,Q8N1F7,Q5JRA6 149 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..fcfa02401aa732659ac5097d23add2044fdf3e6f --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Nuclear receptors", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf35", "C1orf52", "C2CD5", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf33", "CAAP1", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC59", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPI", "CENPL", "CENPP", "CENPQ", "CENPU", "CENPV", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLK", "DOLPP1", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM114A2", "FAM120A", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM207A", "FAM208A", "FAM208B", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMC1", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH8", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LETMD1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM12", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "M6PR", "MACF1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP", "MYDGF", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NENF", "NEPRO", "NES", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "ROMO1", "RP2", "RPA1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RSRC1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35B2", "SLC35F2", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPNS1", "SPOP", "SPOUT1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THEM6", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THYN1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM29", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF3", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED8", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM19", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM223", "TMEM230", "TMEM245", "TMEM33", "TMEM41A", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBFD1", "UBIAD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "UROD", "USMG5", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZCCHC17", "ZCCHC3", "ZCCHC8", "ZDHHC20", "ZEB2", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF148", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF644", "ZPR1", "ZRANB2", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["ABCB1", "ABCB7", "ABCC1", "ABCD4", "ACAT2", "ACOT8", "ACOX3", "ACP2", "ACP6", "ADD3", "ADI1", "ADPGK", "AGK", "AGPAT1", "AIFM1", "AKAP1", "AKT2", "ALDH1B1", "ALDH3A2", "ALG1", "ALG12", "ANKLE2", "ANO6", "AP3B1", "APOB", "ARL6IP5", "ASAH1", "ASNA1", "ATAD3A", "ATL2", "ATP13A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP5L", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP7B", "ATXN10", "AUP1", "B4GAT1", "BCAP31", "BNIP1", "BRI3BP", "C16orf58", "C19orf70", "C3orf58", "CARS2", "CBX1", "CCDC134", "CCDC47", "CCDC6", "CCNB1", "CD47", "CDKAL1", "CEPT1", "CERS2", "CHST14", "CKAP4", "CLCN3", "CLN5", "CLPP", "CLPTM1", "COA3", "COG5", "COG7", "COLEC12", "COMT", "COX15", "COX2", "COX4I1", "COX5A", "COX6C", "CPD", "CPT1A", "CPT2", "CRTAP", "CTSA", "CYB5B", "CYB5D2", "CYFIP2", "CYP20A1", "CYP51A1", "DCTPP1", "DDRGK1", "DENND4C", "DHCR24", "DHPS", "DNAAF2", "DNAJC1", "DNAJC10", "DNM2", "DOLPP1", "DPM1", "DUSP9", "ECE1", "ECH1", "EDRF1", "EIF2B3", "EIF3F", "EMC3", "EMC7", "EMD", "ENDOD1", "EPDR1", "EPHA7", "EPHX1", "ERAP1", "ERGIC2", "ERGIC3", "ERMP1", "EXOC6B", "EXOSC8", "FAM162A", "FAM177A1", "FANCD2", "FARSB", "FDFT1", "FECH", "FKBP14", "FKBP9", "FLAD1", "FLOT1", "FOXRED1", "FUCA2", "GAK", "GALNT7", "GGCX", "GLA", "GLB1", "GLCE", "GLG1", "GNAI2", "GNS", "GOLIM4", "GOLT1B", "GOSR1", "GOSR2", "GPAM", "GPR107", "GPR108", "GPR89B", "GSR", "GSTO1", "HEXA", "HLA-C", "HMGCL", "HMOX1", "HMOX2", "HNRNPK", "HSD17B12", "HSDL1", "ICMT", "IGBP1", "IKBIP", "ILVBL", "IPO11", "ITM2C", "KDELR1", "KDELR3", "KDSR", "KEAP1", "KIAA0319L", "KIAA1468", "KIF11", "LDAH", "LETM1", "LGALS3BP", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LRRC59", "LRRC8C", "LSS", "MAN1A2", "MBNL1", "MBOAT7", "MCM4", "MED24", "MED25", "MFSD10", "MFSD8", "MGEA5", "MGME1", "MIA2", "MIA3", "MIF", "MINPP1", "MPC2", "MPV17L2", "MRC2", "MSMO1", "MSTO1", "MTAP", "MTCH1", "MTCH2", "MTFP1", "MTX1", "NAGLU", "NAMPT", "NANS", "NCEH1", "ND1", "NDC1", "NDUFA11", "NDUFA13", "NDUFAF1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFS2", "NDUFS6", "NECAP1", "NEDD4L", "NEFL", "NENF", "NFU1", "NNT", "NPC1", "NPC2", "NPEPPS", "NSUN2", "NT5C2", "NT5C3B", "NUBPL", "NUCB1", "NUCB2", "NUP107", "NUP54", "NUP93", "OCIAD1", "OCLN", "ODR4", "OGT", "OPA3", "OXA1L", "P3H1", "PAFAH1B3", "PARN", "PCBD1", "PCYOX1", "PCYOX1L", "PEX14", "PFDN1", "PGRMC1", "PGRMC2", "PIGK", "PIP4K2C", "PLA2G15", "PMPCA", "PNN", "PNPLA6", "POLD2", "PON2", "POR", "PPAT", "PPOX", "PPT1", "PPT2", "PREPL", "PRPF31", "PSAP", "PSMB4", "PTGES2", "PUF60", "PXMP2", "QSOX2", "RABAC1", "RDH14", "REEP2", "REEP5", "RETSAT", "RINT1", "RNASET2", "RNF139", "ROMO1", "RPN1", "RPS10", "RTN1", "RTN2", "RTN3", "RTN4", "SCAMP2", "SCARB1", "SCARB2", "SCCPDH", "SCO1", "SCO2", "SCPEP1", "SDF4", "SEC11A", "SEC22B", "SEC63", "SEH1L", "SEL1L", "SETDB1", "SFXN2", "SFXN4", "SGPL1", "SIGMAR1", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A40", "SLC25A42", "SLC25A44", "SLC33A1", "SLC35B2", "SLC35F2", "SLC4A7", "SLC7A1", "SLIT2", "SMIM12", "SMIM4", "SMYD3", "SPNS1", "SPOP", "SPTLC1", "SQLE", "SRP9", "SRPRB", "SSR1", "SSR4", "STAG2", "STIM1", "STOM", "STT3A", "STX10", "STX18", "STX3", "STX6", "STX7", "STX8", "SUN1", "SYNGR2", "SYS1", "TAF15", "TAP1", "TBL1XR1", "TFRC", "TIGAR", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMMDC1", "TLCD1", "TM7SF2", "TM9SF3", "TMED2", "TMED7", "TMED9", "TMEM126A", "TMEM14C", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM230", "TMEM41A", "TMEM59", "TMEM97", "TMX1", "TMX4", "TOMM20", "TOMM22", "TPBG", "TPP1", "TRABD", "TRAM1", "TRMU", "TSPAN3", "TSPAN6", "TTC19", "TTC37", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TWNK", "UBE3A", "UBIAD1", "UBQLN4", "UBXN4", "UFSP2", "UNC119", "UQCR10", "UQCRC2", "UQCRQ", "USMG5", "USP47", "VDAC2", "VIM", "VKORC1L1", "VPS45", 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100644 index 0000000000000000000000000000000000000000..57805c128edf8681151ead1534ac6f3e5da6304a --- /dev/null +++ b/protein_atlas_subcellular_location_all/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f406aea3c921fb92aab837055a27a62384d6730e0338db6fdcf5719376ba545b +size 78595 diff --git a/protein_atlas_subcellular_location_all/df_merge.tsv b/protein_atlas_subcellular_location_all/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..77ba946f6e554f24280c5a0d423919d4f069401e --- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Golgi apparatus 58 175 3.9531860621268944 7.711742344018724e-05 46.45873786407767 176.03155339805826 1.3643789213018729 0.3972771337532677 14.511319530749702 26.453870355965975 1.6568954592349954 0.4161874156663988 0.0021186048048259 0.0365017544971104 0.0005570011653141 0.0025186023386366 4.6307765944992655e-05 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..126f7a25c88d8fcf4390916760834f047d632da4 --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3098, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 142.5151515151515 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d089aa6edbd096f9302e32b7643470b6678e813d --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C177/C177_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..de4d5b472b41a1bd3f5d20099b48fdf36f4d7505 --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,10 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Golgi apparatus 0.4890364102525004 3.9531860621268944 7.711742344018724e-05 0.0025417374071215 0.0025448749735262 175 O43752,O95456,Q9H2V7,Q6NUQ1,Q5VW38,O00461,Q96HV5,Q5VZ89,O60637,O75955,Q9HD45,Q8IZA0,Q8NCH0,Q96GQ5,O15127,P67812,Q9HB40,O43760,Q5BJH7,Q9NWM8,Q9NPR9,Q9BV57,P24390,P50897,Q02818,Q9UP83,Q93050,Q96RQ1,Q9BSR8,Q8IXU6,Q9GZM5,Q86SF2,Q9H3P7,P16278,Q92896,P98194,P50570,P80303,P09601,Q9BRK5,O60476,A1L0T0,Q5KU26,O00203,Q8N4Q0,O95302,A4D1U4,O14653,O95070,O00231,O14976,Q9HC07,Q6ZRP7,P83436,Q8NEY8,O60499,Q8TDW0,P40616 58 +Centriolar satellite 0.5323467847767831 1.8299710231962525 0.0672542719287665 0.8994949541289786 0.4839341718656971 24 Q03518,O43169,Q14145,P41208 4 +Endoplasmic reticulum 0.3649978985221475 1.7908126825151152 0.0733233593735904 0.9189727471532716 0.4839341718656971 208 Q03518,Q96KC8,Q96HY6,Q00765,Q96F07,Q8WUJ1,Q9BRK0,O96005,O95470,P0CG08,Q96PC5,Q5BJF2,Q70UQ0,O43169,Q12981,Q13586,Q96CN7,O75915,Q96G23,Q6UW68,Q9BT22,P37268,Q9H3N1,Q9NQC3,O95197,Q9UGP8,Q86XL3,Q16850,Q8N0U8,O43731,Q96A33,Q99943,P21964,Q9H3G5,Q6PIU2,P50402,P51572,Q15800,P51648,O76062,Q99956,P43307,Q14257,Q9P2W9,Q92575,Q8IY17 46 +Vesicles 0.3858388871521436 1.6294883018751127 0.1032096893146512 0.9725337138035504 0.4865599639119273 291 Q9Y3E0,P30519,Q8N128,Q9H2V7,Q15047,P42785,Q8IXH7,Q9UL15,O75955,Q9UMR5,P07602,P31751,Q9NRV9,Q9HD45,P50336,O00400,Q96GQ5,Q96K76,Q9NRY5,Q9Y487,P27105,Q3SXM5,O15127,O14734,Q5BJH7,Q96CN7,P04114,Q15363,Q9NPR9,P24390,P50897,P51790,Q8WTV0,Q93050,P06865,Q8NHS3,Q96RQ1,Q08722,Q9GZU8,Q8NCC3,O15118,Q8TB61,Q9BSR8,Q32P28,Q53H12,Q9Y5Z9,P21964,Q5JRA6,P16278,Q13277,O75153,Q9HD20,A1L0T0,Q5KU26,Q6P1K2,Q8N4Q0,O95302,Q86YN1,Q9NR50,O76062,Q14534,Q13794,P16435,O95070,O14976,Q6P4A7,Q8NC96,O60499,Q9Y679,Q9UNK0,Q8NBX0 71 +Rods & Rings 0.7848426194882798 1.4983672029844688 0.1340378726058051 0.9913410814057348 0.5529062244989461 4 Q8WTV0 1 +Lysosomes 0.5726107435298539 1.4024257162416751 0.1607881585083954 0.996925582052664 0.58955658119745 11 O60749,Q8IY95,O15400,Q8WTV0 4 +Intermediate filaments 0.3474987831165904 0.6685254930665875 0.5037982145465281 0.9999999999094842 0.9054121087876916 32 P07196,P08670,Q96K76,Q86YN1,O75718,Q3SXM5 6 +Focal adhesion sites 0.3673661003795163 0.5996573596091304 0.5487346113864797 0.999999999996053 0.9054121087876916 24 Q9Y487,P08183 2 +Nuclear membrane 0.3225472724781135 0.1922087544551754 0.8475786886956547 1.0 1.0 64 Q6UW68,Q14728,Q9BTX1,Q9H1E5,Q13277,O95168,O94919,P50402,P57740,P67812,P20700,Q03252,O94901,Q5SNT2,O75976,Q96G23 16 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5e1fac12ce263d7c53900303f018b53878eda0ea --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABAT", "ABCB1", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ADAR", "ADD1", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANF1", "BAP18", "BARD1", "BASP1", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf35", "C1orf52", "C2CD5", "C5orf15", "C5orf24", "C5orf51", "C8orf33", "CAAP1", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC59", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPI", "CENPP", "CENPQ", "CENPU", "CENPV", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHID1", "CHMP2A", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COQ8A", "COQ9", "COTL1", "COX15", "COX4I1", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CWC15", "CWC25", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DOLK", "DOLPP1", "DPF2", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "EMC8", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERH", "ERLIN1", "ERLIN2", "ERP29", "ESCO2", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FAF1", "FAF2", "FAHD1", "FAM114A2", "FAM120A", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM207A", "FAM208A", "FAM208B", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMC1", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLB1", "GLB1L2", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR2", "GOT1", "GPAA1", "GPAM", "GPATCH8", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXIM1", "HGH1", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "IARS", "IARS2", "IBA57", "ICE2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "ISCU", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LETMD1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRWD1", "LSM12", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "MACF1", "MAEA", "MAGED2", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFAP1", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD8", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEFL", "NEFM", "NELFA", "NELFCD", "NELFE", "NEPRO", "NES", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C3A", "NT5DC1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCNP", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGL", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PUS1", "PWP1", "PWP2", "PWWP2A", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB32", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "RP2", "RPA1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSRC1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX2", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPC25", "SPCS2", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STRN4", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THEM6", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THYN1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM23", "TIMM29", "TIMM44", "TIMM50", "TIMMDC1", "TJP1", "TKT", "TLE3", "TLN1", "TM7SF2", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED8", "TMEM109", "TMEM126A", "TMEM126B", "TMEM165", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM223", "TMEM230", "TMEM245", "TMEM41A", "TMEM70", "TMEM97", "TMF1", "TMOD3", "TMPPE", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TST", "TTC1", "TTC19", "TTC37", "TTC4", "TTF1", "TTLL12", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUFM", "TWISTNB", "TXLNA", "TXLNG", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBFD1", "UBIAD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF3B", "UQCC1", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "UROD", "USMG5", "USO1", "USP10", "USP14", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR77", "WDR82", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZDHHC20", "ZEB2", "ZFR", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF148", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF644", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ACBD3", "ACOT8", "ADI1", "AGK", "AGPAT1", "AKT2", "ALDH3A2", "ALG1", "ANKLE2", "AP3B1", "APOB", "ARL1", "ARL6IP5", "ATP13A1", "ATP2C1", "ATP6V0A1", "ATP6V0A2", "AUP1", "BAG5", "BCAP31", "BNIP1", "C16orf58", "CCDC47", "CD47", "CERS2", "CETN2", "CHST14", "CLCN3", "CLPTM1", "CLUH", "COG5", "COG7", "COLEC12", "COMT", "CPD", "CPVL", "CRTAP", "CYB5B", "CYB5D2", "CYFIP2", "CYP51A1", "DDRGK1", "DENND4C", "DNAJC1", "DNM2", "DOLPP1", "DUSP9", "EIF2B3", "EMD", "ENDOD1", "ERGIC2", "FAM114A2", "FAM177A1", "FAM192A", "FDFT1", "FKBP14", "FKBP9", "FLOT1", "GAK", "GALNT7", "GLB1", "GLG1", "GOLIM4", "GOLT1B", "GOSR2", "GPR107", "GPR108", "GPR89B", "HEBP1", "HEXA", "HMOX1", "HMOX2", "HSDL1", "IKBIP", "ILVBL", "ISOC1", "KDELR1", "KDELR3", "KEAP1", "KIAA0319L", "KIAA1147", "LMNB1", "LMNB2", "LRRC8C", "MAN1A2", "MFSD10", "MFSD8", "MIA2", "MIA3", "MSMO1", "NCEH1", "NDC1", "NDUFB4", "NECAP1", "NEFL", "NELFCD", "NPC1", "NUCB1", "NUCB2", "NUP107", "P3H1", "PLA2G15", "PMAIP1", "PMF1", "PNPLA6", "POR", "PPHLN1", "PPOX", "PPT1", "PPT2", "PRCP", "PSAP", "PSMD11", "PSMG1", "QSOX2", "RCN2", "REEP2", "REEP5", "RINT1", "RTN3", "RTN4", "SCAMP2", "SCARB1", "SCCPDH", "SCPEP1", "SDF4", "SEC11A", "SEC63", "SETDB1", "SFXN4", "SGPL1", "SLC33A1", "SLC35B2", "SLC35F2", "SNX2", "SPNS1", "SQLE", "SSR1", "STIM1", "STOM", "STX10", "STX18", "STX3", "STX6", "STX7", "STX8", "SUN1", "SYNGR2", "TAP1", "TM7SF2", "TM9SF3", "TMED2", "TMEM165", "TMEM192", "TMEM201", "TMEM205", "TMEM41A", "TMEM97", "TMX1", "TMX4", "TSPAN3", "UBIAD1", "UBXN4", "USP47", "VIM", "VKORC1L1", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "ZADH2"]} \ No newline at end of file