diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..884813dd16650df34831385d765007d0befa28c2 --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Serine/threonine-protein kinase, active site [IPR008271]"} \ No newline at end of file diff --git a/interpro_active_site/basic/plot_0.png b/interpro_active_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..086272a715b764e9e9264a3399c4536ab4ace9ed --- /dev/null +++ b/interpro_active_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bc2f8c0136af89eb24530d149dbdba0636a3d5ea556c011c6a5b14e6131879c0 +size 156935 diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..5e1520fc024cee6c6249f89d65090bf490786d04 --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:589b410d00e8c99c9b294b7f0e438afe67b5ab2c809c460be86e374b2be9de5c +size 82080 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c9c8eb0b6288079befd1b31e101783b89bd3458f --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 56, + "title": "Average number of proteins per term", + "value": 2.375 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a7c623dd37aa1eb5804236fdd38520468443746a --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e831e3e2bc98aec8993504afb4f6244d3baa1cb3 --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999] 0.6226860302801766 1.3378146169347576 0.180956875812442 0.9999860305581988 0.2202953270760163 3 P00390 1 +ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440] 0.5416801816412493 1.3107612961964945 0.1899384224240572 0.9999924662731152 0.226309609696749 2 P53597 1 +Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.4654557249432233 0.9173654902285066 0.3589511500246853 0.9999999999846572 0.4020252880276476 2 Q9UBT2 1 +Ubiquitin-conjugating enzyme, active site [IPR023313] 0.5137532519712467 0.601976957220751 0.5471894758961056 1.0 0.5892809740419598 6 Q16763 1 +Serine/threonine-protein kinase, active site [IPR008271] 0.2920141239168502 0.4341354919647885 0.664190053570608 1.0 0.701785716980265 36 P31751,Q13131,P78362,P48729,P51812,Q13555,O14976,Q96KB5,Q99570,P50750,O14757,P19525,P24941,P11802,Q00535 15 +ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003] 0.4261447433745844 0.3141633111617788 0.7533970064235813 1.0 0.767095133813101 4 P21281,P06576 2 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8899447727eddfdb297ea0f1df23df240a816d58 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine proteases, trypsin family, histidine active site [IPR018114]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CHEK1", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP11", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAPK1", "MDH1", "MDH2", "MTMR2", "NCEH1", "NEK9", "NME1", "NME6", "OXCT1", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKCA", "PRKCB", "PRPF4B", "PRSS3", "PTK7", "PTPMT1", "PTPN1", "PTPN9", "RIPK1", "RNASET2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "VRK2", "YES1"], "leading_proteins": ["AKT2", "ATP5B", "ATP6V1B2", "CAMK2G", "CDK2", "CDK4", "CDK5", "CDK9", "CHEK1", "CSNK1A1", "EIF2AK2", "GAK", "GSR", "PBK", "PIK3R4", "PRKAA1", "RPS6KA3", "SRPK2", "SUCLG1", "UBA2", "UBE2S"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..9cf297f1a86aa082be5c9c00be47db6924085615 --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4877a35635bbeaca0d5eafd4bab452912fb6610a2bdf9e443617f6669f97b72b +size 137191 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..107ff58c8cb33b8c6bd002c00697aeab3d25e911 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9fc150583301bce21d83cc3758735c5be349b60cadc982e60df22d7a7dc4f14c +size 75166 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..8d053862a470abff3ccb3c322f13359f75a1885d --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 29, + "title": "Average number of proteins per term", + "value": 4.275862068965517 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9943bcca400dac68019171d2918cacdc79621785 --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b40defb159fb9a0155d011288c63b68a8416852a --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EF-Hand 1, calcium-binding site [IPR018247] 0.452936967924691 1.7597147351997502 0.0784561861417108 0.9064672602451638 0.0948012249212338 36 Q96AY3,Q14257,O95302,Q9NWM8,P80303,Q96D71,O43852,Q9BRK5,Q7L5N7 9 +Beta tubulin, autoregulation binding site [IPR013838] 0.6304347826086956 1.3734110658166792 0.1696245915837879 0.9954400519742792 0.1891966598434558 3 P07437,Q9BUF5 2 +Peptidase M16, zinc-binding site [IPR001431] 0.417598961556735 0.2909190835111955 0.7711132057270398 1.0 0.8282327024475613 5 O43847 1 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..42f6b03c2cb29cbb1458c6f539638f973f7a6eb5 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "AURKB", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CETN2", "CHEK1", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP14", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LPCAT2", "LYN", "MACF1", "MAPK1", "MCCC1", "MICU1", "MYH10", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "PA2G4", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKAA2", "PRKCA", "PRKCB", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "TKT", "TUBB", "TUBB2B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["CALU", "FKBP10", "FKBP14", "FKBP9", "LPCAT2", "NRDC", "NUCB2", "RCN2", "REPS1", "SDF4", "TUBB", "TUBB6"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e48ab68eee912c8a8c61fa927b2281c11bdb7d5 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "1": "14-3-3 protein, conserved site [IPR023409]", "2": "Heat shock protein 70, conserved site [IPR018181]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..58b1aeaa792c825738562c7f54d7e4d129ef09b1 --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e0cb523ea10aa4ddbca99213f61454e9b378d9188b240e5174a6653f5b07f100 +size 152394 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..2953a98b28d5a3485d443115a4dc687aeeb4b3b3 --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:776ae0b44e1b1150d18f8c07e634f699468157ae5fd2cce83c83d06ec64cdf37 +size 148402 diff --git a/interpro_conserved_site/basic/plot_2.png b/interpro_conserved_site/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..32f9ad9bb4b5fdaf0759a386ea42158e6a5c1363 --- /dev/null +++ b/interpro_conserved_site/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:faae68c614fef8552671ad3c3d4b02c7e940460db0377ff78dde7d7094cd7b05 +size 154722 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d86698ffb590f611288349337644412f68d69a71 --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6c9f40e27c2fdedcc0aa58b3a8d5b1999e3dd5cfdcd06fec1ea9525fa3e99071 +size 134776 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..593d1674a1536210c22bd04b3a7f11fe38943fe7 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 277, + "title": "Average number of proteins per term", + "value": 2.6823104693140793 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..852a7daa686821592b5c348b065badebddc176c8 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..83c46497e7cb91eedb375e4f9990f19a07861d88 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,33 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Haem oxygenase conserved site [IPR018207] 0.938371715861172 3.2230639150371014 0.001268272507664 0.296392391506826 0.0060570945624644 2 P09601 1 +Tetraspanin, conserved site [IPR018503] 0.9075575737917564 3.08808448072181 0.0020145119389769 0.4279807486049259 0.0079717115299516 2 O60637 1 +DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514] 0.8361985079468044 2.766749466995616 0.0056618247559372 0.7925328114004782 0.0158059457538548 2 O15160 1 +Histidine triad, conserved site [IPR019808] 0.7671099578332747 2.4435078625777615 0.0145452526545226 0.9827272285283348 0.0312328293434323 2 Q9BX68 1 +Dynamin, GTPase region, conserved site [IPR019762] 0.7129419396691479 2.181550371196446 0.0291427330504052 0.9997232791793252 0.0525298777986979 2 P50570 1 +Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717] 0.7203446064450654 1.7829508450753675 0.0745943052732567 0.9999999995279256 0.1093260452946672 3 Q07812 1 +Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728] 0.7203446064450654 1.7829508450753675 0.0745943052732567 0.9999999995279256 0.1093260452946672 3 Q07812 1 +Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726] 0.7203446064450654 1.7829508450753675 0.0745943052732567 0.9999999995279256 0.1093260452946672 3 Q07812 1 +Ubiquitin conserved site [IPR019954] 0.7131884040174735 1.750712726420597 0.0799954061542655 0.9999999999067112 0.1160210385524679 3 P46379 1 +Proteasome beta-type subunit, conserved site [IPR016050] 0.7513070658592702 1.7455197717104738 0.0808944338756123 0.9999999999288436 0.1167070738726282 8 P20618,P28070,P49721,P28074 4 +Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.781498594230539 1.682278584400498 0.0925148318473163 0.9999999999979032 0.1304488656313982 5 P48735 1 +Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.6596365996106425 1.5073032902323626 0.1317329346224078 1.0 0.1713146614573097 3 Q9Y2T2,Q96CW1 2 +Aldehyde dehydrogenase, glutamic acid active site [IPR029510] 0.706009013307414 1.4558956398697542 0.1454214711776567 1.0 0.1873569651916786 7 P49419 1 +Ubiquitin specific protease, conserved site [IPR018200] 0.6526208802574656 1.4166665627813342 0.1565804374769184 1.0 0.2007999128754926 9 Q86UV5,Q9P275,Q96K76,P45974 4 +Profilin conserved site [IPR027310] 0.5569250729808544 1.3900082780350131 0.1645263636484357 1.0 0.2100175241042244 2 P35080 1 +Tubulin, conserved site [IPR017975] 0.6304347826086956 1.3734110658166792 0.1696245915837879 1.0 0.2145479994004989 3 P07437,Q9BUF5 2 +ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847] 0.5416801816412493 1.3107612961964945 0.1899384224240572 1.0 0.2329600581871062 2 P53597 1 +FERM conserved site [IPR019747] 0.6259111449959486 1.2909446518108754 0.1967228705558827 1.0 0.2390010313332435 9 Q9Y2J2,Q9Y4F1 2 +Actin, conserved site [IPR004001] 0.5072980862795864 1.13217939156283 0.2575590224448434 1.0 0.3048882445180411 2 O96019 1 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.5532121998702171 1.01972834797462 0.3078573133447229 1.0 0.3583045201533119 3 P09429,O15347 2 +Oxysterol-binding protein, conserved site [IPR018494] 0.6081874619605018 0.961817407557183 0.3361413322450439 1.0 0.3847568141813106 4 Q9BZF1,Q9BZF3 2 +Ubiquitin-activating enzyme E1, conserved site [IPR018074] 0.4654557249432233 0.9173654902285066 0.3589511500246853 1.0 0.4091747677236125 2 Q9UBT2 1 +Zinc finger, RING-type, conserved site [IPR017907] 0.4062909332439567 0.8516605667958211 0.3944025129770789 1.0 0.4441036426611824 17 Q9P1Y6,Q14527,P14373 3 +Guanylate kinase, conserved site [IPR020590] 0.5424885047090829 0.7038164159950684 0.4815471091672545 1.0 0.5314284830252172 4 O14936,Q00013 2 +Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412] 0.3683883488754475 0.523071976029479 0.6009241663990459 1.0 0.647688692967065 15 Q5T160,P26640,Q5JPH6,Q9NSE4 4 +D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753] 0.4345991561181493 0.3378893156721883 0.7354465993955484 1.0 0.7775523207349881 4 P56545,Q13363,Q9UBQ7 3 +Procollagen-lysine 5-dioxygenase, conserved site [IPR001006] 0.3820961944921607 0.3274562793988142 0.7433228057048336 1.0 0.77992582265242 3 O00469 1 +DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.3096942094990321 0.1571916073566241 0.875093842435454 1.0 0.9112819336639878 11 Q14562,P54132,Q7L2E3,Q9H2U1,Q86WJ1,O43143,Q92620,Q6P158,Q14839,Q08211 10 +Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.3362847721581593 0.1243599030996179 0.9010303195316708 1.0 0.9257158805341476 4 P42345,P42356 2 +Bromodomain, conserved site [IPR018359] 0.2811303252337053 0.1225152137518615 0.9024909979245068 1.0 0.9257158805341476 12 Q15059,P25440,Q9BXF3 3 +14-3-3 protein, conserved site [IPR023409] 0.2559272491068595 0.0526408485587751 0.9580180696294368 1.0 0.9685073185669854 6 P27348,P61981,P62258,Q04917,P63104 5 +Heat shock protein 70, conserved site [IPR018181] 0.2174902470741296 0.0466095678572067 0.9628244062724802 1.0 0.9698267655908256 9 P0DMV9,O95757,P54652,Q92598,P11142,P38646,Q9Y4L1,P34932 8 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ed88f8ea8b30ef9d4781212e8cfff7c6217d3ca2 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycerate/sugar phosphate transporter, conserved site [IPR021159]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinate dehydrogenase, cytochrome b subunit, conserved site [IPR018495]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APLP2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7A", "ATP7B", "BAG6", "BAK1", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BLM", "BMI1", "BOP1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDKAL1", "CECR2", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX38", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "EPS15", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FTL", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GFM2", "GLA", "GLB1", "GLB1L2", "GLO1", "GNPDA1", "GNS", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXD11", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPAD1", "IMPDH2", "INA", "ING5", "IQGAP1", "IQGAP2", "ITGAV", "IVD", "KDM2A", "KDSR", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MOCS1", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPST", "MRC2", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSD3", "NSF", "NTHL1", "NUBP1", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PHF2", "PHF3", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SDHC", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A2", "SLC27A4", "SLC2A1", "SLC37A4", "SLC4A2", "SLC5A6", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STMN1", "STOM", "STRN", "STRN4", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TM7SF2", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP13", "TSFM", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBFD1", "UHRF1", "USP10", "USP14", "USP19", "USP36", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ACTL6A", "ALDH7A1", "AP2M1", 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@@ +version https://git-lfs.github.com/spec/v1 +oid sha256:27e4ee4d4c1e900a4a72b8f681d6b6688b6e68487905a3aa16042ad38753be2a +size 137535 diff --git a/interpro_domain/basic/plot_8.png b/interpro_domain/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..3e41ebbf8c605d8ee73b447798f5cfb18d0c5c56 --- /dev/null +++ b/interpro_domain/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:79329884497bebacb1e8a6147adf019f919024c3ca0affdb6715921b82c1ed53 +size 145569 diff --git a/interpro_domain/basic/plot_9.png b/interpro_domain/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..9c98bc32d3de537dca32ef7dc7ced6c3844ec2f6 --- /dev/null +++ b/interpro_domain/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:28bf18b7380ef12fcd2736ba9faac7b6e41f879cfed33d1995edf81a8da4990d +size 146356 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..1236e9ec276da495e8c4dc7515dae43fe3a00e7c --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2815c602571e2e4d846cfb5c6387b77aa59d47a778573db69b2f88d779a9c9c3 +size 757079 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..70e5ba9564b9b81729f8c38922240267936da30f --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Zinc finger, CXXC-type [IPR002857] 1 5 2.331002657029625 0.0197532195774639 1.2257281553398058 3.0825242718446604 -0.1736537271013689 0.496442226948843 1.0520521803495066 0.8550168549370308 1.1267939265774038 0.325811097006037 0.0128766161439974 0.0561990347849709 0.0057815105752346 0.0333651833289618 0.1141066789781333 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 3 9 2.0348426606647565 0.0418667070050917 3.1262135922330097 10.111650485436892 0.9686720267359892 0.3700536707457866 1.7316562118191232 1.203619216216406 0.9607394322697528 0.3108814801432357 1.0 0.0607401038440192 0.0067896670197663 0.0002086676392486 0.0002552418837429 +Cyclic nucleotide-binding domain [IPR000595] 0 5 1.9818106067482733 0.047500441893058 1.4902912621359223 4.660194174757281 -0.0126471736913758 0.4102849468515657 0.986512397936728 0.870814795980239 1.213781652340298 0.307139032821674 1.0 0.0470522829573702 0.0930016660897952 0.2191369015278419 0.3946911962196813 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6dbe43569db9c34aa4e10e7b340dcdb09318a393 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 2486, + "title": "Average number of proteins per term", + "value": 2.174979887369268 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7394caef87f20991a4bef77e8e24bd145a278738 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7cc8e73b220a9b53da69f903647e7082bfe01aaa --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,227 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +GMP phosphodiesterase, delta subunit [IPR008015] 0.9701589361011986 3.3600129029369525 0.0007793883241291 0.856053679313284 0.0042398116463807 2 Q13432 1 +Marvel domain [IPR008253] 0.9581576386636382 3.308576752899491 0.0009377147799392 0.902923175401208 0.0046904606497562 2 O43760 1 +Myotubularin-like phosphatase domain [IPR010569] 0.9516704508595516 3.280638126055131 0.001035725367636 0.9239335200641888 0.004961104554804 2 Q9C0I1 1 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.9143691209860488 3.1181138332861895 0.0018201248933009 0.989208034604535 0.0072051440839907 2 P98179 1 +Class II aldolase/adducin N-terminal [IPR001303] 0.9007460265974684 3.0579450049244525 0.0022286047175363 0.9960988897912656 0.0081836208682355 2 Q9UEY8 1 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.9004216672072607 3.0565070334619264 0.0022393222676257 0.9962016844300224 0.0082108483146279 2 Q32P28 1 +GINS subunit, domain A [IPR021151] 0.8705806033084642 2.923129418919096 0.0034653244921512 0.9998212920759194 0.0109964713756265 2 Q9BRT9 1 +DNA-directed RNA polymerase, insert domain [IPR011262] 0.8361985079468044 2.766749466995616 0.0056618247559372 0.999999259020825 0.0157971900597755 2 O15160 1 +DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263] 0.8361985079468044 2.766749466995616 0.0056618247559372 0.999999259020825 0.0157971900597755 2 O15160 1 +Guanine nucleotide exchange factor, N-terminal [IPR032691] 0.8245215698994486 2.7129683107127054 0.0066683483145659 0.999999940246208 0.0177675473224671 2 Q7Z3U7 1 +Leucine-rich repeat N-terminal domain [IPR000372] 0.8238728511190326 2.709970398079699 0.0067289213317318 0.9999999486516592 0.0177820502737711 2 O94813 1 +Cysteine-rich flanking region, C-terminal [IPR000483] 0.8238728511190326 2.709970398079699 0.0067289213317318 0.9999999486516592 0.0177820502737711 2 O94813 1 +GPAT/DHAPAT, acyltransferase domain [IPR041728] 0.8151151475835161 2.669394441380922 0.0075988154188508 0.99999999418482 0.019454845655266 2 O15228 1 +Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520] 0.8151151475835161 2.669394441380922 0.0075988154188508 0.99999999418482 0.019454845655266 2 O15228 1 +Legume-like lectin [IPR005052] 0.7894907557573754 2.5495527996193124 0.0107861176972092 0.9999999999980436 0.02534431814297 2 Q12907 1 +Longin domain [IPR010908] 0.8884240679694873 2.5137885070101413 0.011944203807221 0.9999999999998936 0.0271916581179043 3 P51809 1 +v-SNARE, coiled-coil homology domain [IPR042855] 0.8884240679694873 2.5137885070101413 0.011944203807221 0.9999999999998936 0.0271916581179043 3 P51809 1 +Zinc finger, MYND-type [IPR002893] 0.8838583788484862 2.494659309934799 0.0126078116725367 0.99999999999998 0.028471980039752 3 Q9H7B4 1 +Occludin homology domain [IPR010844] 0.7697048329549032 2.4558687196595534 0.014054448982526 0.9999999999999994 0.0306485615531226 2 Q16625 1 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.7680830360038833 2.448145206903454 0.014359377259455 0.9999999999999998 0.0311811740099408 2 Q5T9A4 1 +EB1, C-terminal [IPR004953] 0.7658125202724512 2.4373209608444006 0.0147965394788902 1.0 0.0319584684140062 2 Q15555 1 +Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164] 0.7632176451508209 2.4249342123148425 0.0153111610828151 1.0 0.0325607754079371 2 O95782 1 +Pre-SET domain [IPR007728] 0.8569110966904439 2.3809114183022375 0.0172698642376993 1.0 0.0355699109319972 3 Q96KQ7,Q15047 2 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.8564190972011221 2.3788212039495304 0.0173680979606922 1.0 0.0357426254389743 3 P52888 1 +26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135] 0.7457022380797921 2.340872625476929 0.0192387294634814 1.0 0.0387580886922325 2 Q13098 1 +Zinc finger, CXXC-type [IPR002857] 0.9441399883203688 2.331002657029625 0.0197532195774639 1.0 0.0393481601519032 5 Q03164 1 +MATH/TRAF domain [IPR002083] 0.7427830035679429 2.3267861072075435 0.0199766521987561 1.0 0.0397295658928861 2 O43791 1 +ERAP1-like C-terminal domain [IPR024571] 0.8413264566455723 2.3144683367155685 0.0206420461501088 1.0 0.0407316404915714 3 P55786 1 +SGS domain [IPR007699] 0.7187804086928244 2.2101427774980613 0.0270952548295593 1.0 0.0504182660975183 2 Q9Y2Z0 1 +CTP synthase, N-terminal [IPR017456] 0.7174829711320041 2.203796287485005 0.0275386737953826 1.0 0.050872455449706 2 P17812 1 +CTP synthase GATase domain [IPR033828] 0.7174829711320041 2.203796287485005 0.0275386737953826 1.0 0.050872455449706 2 P17812 1 +Dynamin stalk domain [IPR000375] 0.7129419396691479 2.181550371196446 0.0291427330504052 1.0 0.0529209893084788 2 P50570 1 +GTPase effector domain [IPR020850] 0.7129419396691479 2.181550371196446 0.0291427330504052 1.0 0.0529209893084788 2 P50570 1 +Dynamin GTPase effector [IPR003130] 0.7129419396691479 2.181550371196446 0.0291427330504052 1.0 0.0529209893084788 2 P50570 1 +Peptidase S9A, N-terminal domain [IPR023302] 0.7090496269866975 2.162441473552452 0.0305841637117065 1.0 0.0546601229240133 2 P48147 1 +PTB/PI domain [IPR006020] 0.7019137204022055 2.1273108536946848 0.0333942635408903 1.0 0.0577521262057129 2 O60343 1 +Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099] 0.7012650016217927 2.124110925876464 0.0336608691073117 1.0 0.0579507760393191 2 Q14558 1 +LEM-like domain [IPR013146] 0.6999675640609726 2.117707965460312 0.0341998078487897 1.0 0.0587565461728343 2 P42166 1 +NET domain [IPR027353] 0.7871890594875404 2.079965787692905 0.0375286710079811 1.0 0.0625729551481161 3 Q15059 1 +Brdt, bromodomain, repeat I [IPR043508] 0.7871890594875404 2.079965787692905 0.0375286710079811 1.0 0.0625729551481161 3 Q15059 1 +Brdt, bromodomain, repeat II [IPR043509] 0.7871890594875404 2.079965787692905 0.0375286710079811 1.0 0.0625729551481161 3 Q15059 1 +MHC class I, alpha chain, C-terminal [IPR010579] 0.6899124229646387 2.0679455036017824 0.0386451478779421 1.0 0.0639626082720134 2 P04439 1 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.6899124229646387 2.0679455036017824 0.0386451478779421 1.0 0.0639626082720134 2 P04439 1 +CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.7835820895522203 2.0641422294982 0.0390042330358477 1.0 0.0644710926377111 3 Q9NUQ9,Q96F07 2 +Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187] 0.6843983133311694 2.040552456736324 0.0412953319422051 1.0 0.0674065628419711 2 O75694 1 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.7858600993531316 2.0348426606647565 0.0418667070050917 1.0 0.0681155979153521 9 O95302,P26885,Q9NWM8 3 +Peptidase M20, dimerisation domain [IPR011650] 0.6753162504054406 1.9952764669118088 0.0460127350920278 1.0 0.0727194274880999 2 Q8IYS1 1 +Peptidase M28 [IPR007484] 0.7562546852971301 1.9434817698095757 0.0519579759378587 1.0 0.0794877096501642 3 Q969V3 1 +Man1/Src1, C-terminal [IPR018996] 0.658773921505025 1.91231627246473 0.0558356398931998 1.0 0.0829481321670103 2 Q8NC56 1 +Intermediate filament head, DNA-binding domain [IPR006821] 0.8391272302638688 1.9026074752536992 0.0570917830163071 1.0 0.0841528310833188 4 P07196 1 +Glutamine amidotransferase type 2 domain [IPR017932] 0.6555303276029842 1.8959768595876616 0.0579631044899957 1.0 0.0851129815488065 2 P08243 1 +Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.6539085306519612 1.8877984161314345 0.0590530179127066 1.0 0.0862548781028136 2 P31689 1 +PABP, RNA recognition motif 2 [IPR045305] 0.6519623743107363 1.877976657471527 0.0603843584210759 1.0 0.0878382182766499 2 Q13310 1 +Elongation factor G, domain III [IPR009022] 0.6480700616282808 1.8583084124675529 0.0631252298813067 1.0 0.0910791186795871 2 Q96RP9 1 +EFG, domain V [IPR035649] 0.6480700616282808 1.8583084124675529 0.0631252298813067 1.0 0.0910791186795871 2 Q96RP9 1 +CARG-binding factor, N-terminal [IPR012956] 0.6474213428478636 1.8550271931418136 0.0635923434697383 1.0 0.091487595987135 2 Q99729 1 +Glycosyl transferase, family 1 [IPR001296] 0.7349286392427332 1.8484038081446332 0.0645439482353951 1.0 0.0926037098665978 3 Q9BT22 1 +SET domain [IPR001214] 0.7150243412959527 1.8483315359466248 0.0645543962987988 1.0 0.0926037098665978 10 Q03164,Q15047 2 +CAP Gly-rich domain [IPR000938] 0.7339390006489257 1.8439731322660464 0.0651870558692642 1.0 0.0934573361539739 3 Q14203,Q99426 2 +Zinc finger, UBR-type [IPR003126] 0.7337553479333765 1.843150730842131 0.0653070061156471 1.0 0.0935753413276649 3 Q5T4S7 1 +Zinc finger, CHHC-type [IPR012996] 0.7333811545636739 1.8414749131326031 0.0655519936111312 1.0 0.0938122592584594 3 P52597 1 +Importin-beta, N-terminal domain [IPR001494] 0.625426648715453 1.7734847546763282 0.0761484158863503 1.0 0.1055800122105225 13 O43592,Q9UI26,P55060,Q9UIA9,O00410,Q96P70,Q92973,O95373,Q9HAV4 9 +FAD dependent oxidoreductase [IPR006076] 0.8053249614409703 1.7669852464118845 0.07723069915472 1.0 0.1067828243040233 4 Q96CU9 1 +Complex 1 LYR protein domain [IPR008011] 0.6292572169964278 1.7627963595460046 0.0779348416427714 1.0 0.1074575797692344 2 Q9Y6M9 1 +Ras-associating (RA) domain [IPR000159] 0.6276354200453985 1.7545290787611556 0.0793398917671939 1.0 0.1085594864119992 2 P55196 1 +Dynamin, GTPase domain [IPR001401] 0.7131732641142015 1.750644440807908 0.0800071751664572 1.0 0.1092245126105506 3 O60313,P50570 2 +W2 domain [IPR003307] 0.7940808722404004 1.7473721123007933 0.0805728116872372 1.0 0.1099363391078331 6 Q9Y6E2 1 +Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141] 0.6227700291923406 1.7296968239037895 0.0836844564661092 1.0 0.1128809325961733 2 P20020 1 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.7924662968473756 1.727143619210488 0.0841418735119097 1.0 0.1133749038214675 5 P55786 1 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.7924662968473756 1.727143619210488 0.0841418735119097 1.0 0.1133749038214675 5 P55786 1 +DNA polymerase alpha/delta/epsilon, subunit B [IPR007185] 0.707657365347153 1.7257436594335127 0.0843935397540391 1.0 0.1135908715909807 3 P56282,P49005 2 +Ras GTPase-activating domain [IPR001936] 0.7066226740001419 1.7210677759562223 0.0852385258825045 1.0 0.1145421488345439 3 Q13576 1 +Coatomer, WD associated region [IPR006692] 0.6185533571196857 1.7081394751484358 0.087610465750042 1.0 0.116782636919359 2 P53621 1 +Death domain [IPR000488] 0.7021204715033734 1.700704185446707 0.0889985487958051 1.0 0.1181262105212875 3 Q12955 1 +Isopropylmalate dehydrogenase-like domain [IPR024084] 0.781498594230539 1.682278584400498 0.0925148318473163 1.0 0.1220778256488575 5 P48735 1 +Cold shock domain [IPR011129] 0.6952252508852319 1.6694628137530958 0.0950256940929417 1.0 0.1243336186921332 3 P16989 1 +Cold-shock protein, DNA-binding [IPR002059] 0.6952252508852319 1.6694628137530958 0.0950256940929417 1.0 0.1243336186921332 3 P16989 1 +Cold-shock (CSD) domain [IPR019844] 0.6952252508852319 1.6694628137530958 0.0950256940929417 1.0 0.1243336186921332 3 P16989 1 +GYF domain [IPR003169] 0.6062277002919203 1.6449433687666315 0.0999814902070439 1.0 0.1295901901223729 2 Q6Y7W6 1 +Post-SET domain [IPR003616] 0.7459907667993604 1.628664336600372 0.1033840964202761 1.0 0.1333746049303614 7 Q03164 1 +Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.663393768676926 1.5971288225232831 0.1102369945981882 1.0 0.1396784753165627 10 P11310 1 +FERM adjacent (FA) [IPR014847] 0.7591282703375051 1.5903881979375027 0.111747328959469 1.0 0.1414479937847454 5 Q9Y2J2,Q9Y4F1 2 +Aldehyde dehydrogenase domain [IPR015590] 0.6817806238563698 1.5536706393347224 0.1202629999870494 1.0 0.1491141236747157 9 P49419 1 +Exportin-2, central domain [IPR013713] 0.6525767258004387 1.474985012904659 0.1402165727387929 1.0 0.169624525464058 3 O95373 1 +Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004] 0.6521739130434745 1.4731398571025558 0.1407133281532249 1.0 0.1699773244844106 3 O95071,Q13310 2 +EF-hand domain [IPR002048] 0.3983341942610162 1.457227289649982 0.1450536499709791 1.0 0.17513519855651 44 Q9BRK5,Q96AY3,Q14257,O95302,Q9NWM8,P80303,Q96D71,O43852,Q99653,Q7L5N7 10 +Beta-adaptin appendage, C-terminal subdomain [IPR015151] 0.6349772874756741 1.394269826835852 0.1632361388713494 1.0 0.1956629899875481 3 O00203,P63010 2 +AMPK, C-terminal adenylate sensor domain [IPR032270] 0.5559519948102413 1.384952773401118 0.1660669085777586 1.0 0.1989601613129195 2 Q13131 1 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.6304347826086956 1.3734110658166792 0.1696245915837879 1.0 0.202344882282772 3 P07437,Q9BUF5 2 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.6304347826086956 1.3734110658166792 0.1696245915837879 1.0 0.202344882282772 3 P07437,Q9BUF5 2 +FERM, N-terminal [IPR018979] 0.6642361608498303 1.354860730640569 0.1754619331005695 1.0 0.208907263260544 8 Q9Y2J2,Q9Y4F1 2 +FERM, C-terminal PH-like domain [IPR018980] 0.6642361608498303 1.354860730640569 0.1754619331005695 1.0 0.208907263260544 8 Q9Y2J2,Q9Y4F1 2 +Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099] 0.6226860302801766 1.3378146169347576 0.180956875812442 1.0 0.2147297342576281 3 P00390 1 +Peptidase M41 [IPR000642] 0.5465455724943176 1.3360606208594683 0.1815294598901276 1.0 0.215306410919302 2 Q96TA2 1 +Cobalamin (vitamin B12)-binding domain [IPR006158] 0.5426532598118623 1.315821445972351 0.1882339793907124 1.0 0.2222500323653501 2 Q99707 1 +CoA-binding [IPR003781] 0.5416801816412493 1.3107612961964945 0.1899384224240572 1.0 0.2236792601355785 2 P53597 1 +FERM domain [IPR000299] 0.6259111449959486 1.2909446518108754 0.1967228705558827 1.0 0.2310123080783772 9 Q9Y2J2,Q9Y4F1 2 +FERM central domain [IPR019748] 0.5991333081055242 1.2810537180592652 0.2001747985555617 1.0 0.2348440534257322 10 Q9Y2J2,Q9Y4F1 2 +Band 4.1 domain [IPR019749] 0.5991333081055242 1.2810537180592652 0.2001747985555617 1.0 0.2348440534257322 10 Q9Y2J2,Q9Y4F1 2 +LIS1 homology motif [IPR006594] 0.5687587092874111 1.2298521517308254 0.2187524747506404 1.0 0.2549548299250314 11 Q9BZK7 1 +JmjC domain [IPR003347] 0.6721050586366166 1.22242207390859 0.2215480559522973 1.0 0.2578504059444809 4 Q9Y2K7 1 +YjeF N-terminal domain [IPR004443] 0.5183263055465379 1.1893729982685486 0.2342929213764533 1.0 0.2721739264214313 2 Q8NCW5 1 +FATC domain [IPR003152] 0.5895929030465193 1.185820190231981 0.2356933163417252 1.0 0.2734174449022533 3 P42345 1 +PIK-related kinase, FAT [IPR003151] 0.5895929030465193 1.185820190231981 0.2356933163417252 1.0 0.2734174449022533 3 P42345 1 +PIK-related kinase [IPR014009] 0.5895929030465193 1.185820190231981 0.2356933163417252 1.0 0.2734174449022533 3 P42345 1 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.6552448326671034 1.16845756149297 0.2426222480568018 1.0 0.281061933210256 6 Q8WUJ1 1 +Reticulon [IPR003388] 0.6533385011648065 1.14544386099096 0.2520253380325701 1.0 0.2916829564008237 4 Q16799 1 +Bromodomain [IPR001487] 0.4493782904626278 1.1227738192298984 0.2615335671984931 1.0 0.3018442191529497 17 Q15059,Q03164 2 +CLASP N-terminal domain [IPR024395] 0.505027570548156 1.1204228910409095 0.2625335946947271 1.0 0.3028577802371655 2 Q14008 1 +Splicing factor RBM39, linker [IPR029123] 0.504054492377543 1.1153867194129004 0.264684738128216 1.0 0.3051830350147805 2 Q86U06 1 +Proteasome component (PCI) domain [IPR000717] 0.4407190950230114 1.0966480636104283 0.2727952681826164 1.0 0.3138218587237318 18 P61201,Q9Y262,P60228,Q7L2H7,Q15008,Q5JVF3,O00231,Q13098,Q9BT78 9 +Zinc finger, PHD-finger [IPR019787] 0.4112718934442055 1.0933166450188352 0.2742547971783391 1.0 0.3152132087268892 24 Q96T88,Q03164,Q8WUB8,Q9Y2K7,Q9P1Y6 5 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.6389584346112445 1.0930197916516848 0.2743851100905021 1.0 0.3152132087268892 5 Q32P28 1 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.6389584346112445 1.0930197916516848 0.2743851100905021 1.0 0.3152132087268892 5 Q32P28 1 +Ubiquitin-conjugating enzyme E2 [IPR000608] 0.5824839074595596 1.087359993778968 0.2768777443278727 1.0 0.3174773672769515 9 Q9Y385,Q9C0C9,Q16763 3 +Exportin-1/Importin-beta-like [IPR013598] 0.6382039749080992 1.083574803466678 0.278553367573997 1.0 0.3188230533098327 4 O43592,Q9HAV4 2 +FAD/NAD(P)-binding domain [IPR023753] 0.6357610448619707 1.0798586987269032 0.2802051074243907 1.0 0.3204185359048001 5 O95831,P00390 2 +HECT domain [IPR000569] 0.6052535680256145 1.0201221201354311 0.3076705471804275 1.0 0.3498943185226636 7 Q96PU5,Q05086 2 +PUA domain [IPR002478] 0.5476963011031848 0.9947403515128844 0.3198625635967658 1.0 0.3627638380937772 3 O60832,P41214 2 +Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394] 0.5400841893736631 0.9925507339766468 0.3209289436661742 1.0 0.3636414557675975 10 Q86UV5,Q9P275,Q96K76,P45974 4 +Ubiquitin specific protease domain [IPR028889] 0.5400841893736631 0.9925507339766468 0.3209289436661742 1.0 0.3636414557675975 10 Q86UV5,Q9P275,Q96K76,P45974 4 +OBG-type guanine nucleotide-binding (G) domain [IPR031167] 0.6132104813454089 0.98747947971033 0.3234076377614112 1.0 0.3662830922436758 5 Q9NTK5,A4D1E9 2 +Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155] 0.6098294377385872 0.9801256141397828 0.3270241169481931 1.0 0.3695372521514582 6 P26640,Q9NSE4 2 +Aminoacyl-tRNA synthetase, class Ia [IPR002300] 0.6098294377385872 0.9801256141397828 0.3270241169481931 1.0 0.3695372521514582 6 P26640,Q9NSE4 2 +Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152] 0.6094155844155975 0.9720256495091568 0.3310377883888273 1.0 0.3735632963843054 5 O95782,P63010,O94973,Q10567 4 +Dehydrogenase, E1 component [IPR001017] 0.5413371063447614 0.9660214664266696 0.3340334395814333 1.0 0.3767727453717981 3 Q02218 1 +Ubiquitin-like domain [IPR000626] 0.458850073867409 0.9574047981103349 0.3383629776051635 1.0 0.3814831575176582 14 Q96T88,Q99426,Q86UV5,Q15813,P46379,Q9NRR5 6 +L27 domain, C-terminal [IPR014775] 0.5370204342675386 0.9465873688669678 0.3438490828201019 1.0 0.3869147569823677 3 O14936 1 +L27 domain [IPR004172] 0.5370204342675386 0.9465873688669678 0.3438490828201019 1.0 0.3869147569823677 3 O14936 1 +Mu homology domain [IPR028565] 0.6043492372606336 0.9463721314396604 0.3439588145338024 1.0 0.3869147569823677 4 Q9BXS5,Q9Y2T2,Q96CW1 3 +Phosphoribosyltransferase domain [IPR000836] 0.6014096427121074 0.9395290153685412 0.3474592022309843 1.0 0.3906755209164301 5 O60256,Q06203 2 +Sec24-like, trunk domain [IPR041742] 0.532884309511835 0.9280163417469705 0.3533990928272426 1.0 0.3962788203737145 3 O95487 1 +Sorting nexin Vps5-like, C-terminal [IPR015404] 0.5298342774625842 0.9143554997742734 0.3605300766589145 1.0 0.4040927730270791 3 O60749 1 +Methylglyoxal synthase-like domain [IPR011607] 0.4644826467726104 0.912434323006204 0.3615401282280741 1.0 0.4050422527151835 2 P27708 1 +Ubiquitin-associated domain [IPR015940] 0.5185021710723325 0.8892767318840292 0.3738543733525279 1.0 0.4175211015967585 10 Q9Y5A7,Q9NRR5 2 +Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553] 0.5128911900707984 0.8627426434886164 0.3882789807873554 1.0 0.431305427273175 10 O00203,Q10567,O95782,Q9Y678,P63010,O43747,O94973 7 +SWIB/MDM2 domain [IPR003121] 0.5181700194678847 0.8624053911533713 0.38846447489149 1.0 0.4313187514873802 3 Q92925,P41214 2 +Pleckstrin homology domain [IPR001849] 0.4037948781807371 0.8599667841787515 0.3898073525379912 1.0 0.4326165528613599 18 Q6WCQ1,P50570,Q9Y4F1,P31751,Q9BZF1,Q9BZF3,Q9Y5P4 7 +BTB/POZ domain [IPR000210] 0.5738623386883611 0.8290578631666886 0.4070716656682254 1.0 0.450770672984948 5 O43791 1 +THIF-type NAD/FAD binding fold [IPR000594] 0.5698894619370454 0.8133323907556363 0.4160275109026334 1.0 0.4598685602952186 5 Q13564,Q9UBE0,A0AVT1 3 +Glutamine amidotransferase [IPR017926] 0.5699448231093843 0.80972845139411 0.4180962621533095 1.0 0.4619499145391678 4 Q9NRF8,P49915,P17812 3 +Zinc finger, RING-type [IPR001841] 0.3683743273667492 0.7882003010226728 0.430579553083217 1.0 0.4751090852041179 24 Q9P1Y6,Q14527,Q96DX4,P14373 4 +Zinc finger, PHD-type [IPR001965] 0.3601138104066834 0.7807716792721558 0.4349367937059407 1.0 0.4790664019286525 27 Q96T88,Q03164,Q8WUB8,Q9Y2K7,Q9P1Y6 5 +SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678] 0.5569688040581569 0.7626246021574045 0.4456873079948997 1.0 0.4898225674957209 5 Q08J23,Q96CB9 2 +Zinc finger, CCHC-type [IPR001878] 0.5281835245550216 0.7536521358651748 0.4510581297022602 1.0 0.4955061910913915 8 Q16629 1 +TOG domain [IPR034085] 0.5392043176038103 0.6978731806010797 0.4852565080863096 1.0 0.5307292912901741 6 O00410 1 +LEM domain [IPR003887] 0.5372226959687383 0.6902648619962459 0.4900276405769124 1.0 0.5344612043027185 6 P42167,Q8NC56,P50402,P42166 4 +B30.2/SPRY domain [IPR001870] 0.4435286236303473 0.6896909172954413 0.4903885788473454 1.0 0.5344612043027185 12 P14373 1 +SPRY domain [IPR003877] 0.4435286236303473 0.6896909172954413 0.4903885788473454 1.0 0.5344612043027185 12 P14373 1 +WW domain [IPR001202] 0.4077764688349141 0.6772014735366958 0.4982781329656505 1.0 0.5428218398565325 14 Q13576,Q96PU5,Q96J02 3 +DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.5299315059584732 0.6566147792161535 0.5114286434556823 1.0 0.5566600733935316 4 P42694,Q9HCE1 2 +RecF/RecN/SMC, N-terminal [IPR003395] 0.523721232993331 0.6390426660541362 0.5227951762754954 1.0 0.5680370665301057 6 Q9NTJ3,Q96SB8 2 +Tyrosine-specific protein phosphatases domain [IPR000387] 0.4985393438560938 0.6318587485932813 0.5274791807743968 1.0 0.5710867382405754 8 Q99956 1 +Sec23/Sec24, trunk domain [IPR006896] 0.5225620178970521 0.6315676300507531 0.5276694439817384 1.0 0.5710867382405754 5 O95487,Q15436 2 +Zinc finger, Sec23/Sec24-type [IPR006895] 0.5225620178970521 0.6315676300507531 0.5276694439817384 1.0 0.5710867382405754 5 O95487,Q15436 2 +Sec23/Sec24, helical domain [IPR006900] 0.5225620178970521 0.6315676300507531 0.5276694439817384 1.0 0.5710867382405754 5 O95487,Q15436 2 +Sec23/Sec24 beta-sandwich [IPR012990] 0.5225620178970521 0.6315676300507531 0.5276694439817384 1.0 0.5710867382405754 5 O95487,Q15436 2 +OCRE domain [IPR041591] 0.4607762629220822 0.6165891158034269 0.5375057754475372 1.0 0.5799649990288964 3 P78332 1 +Zinc finger, PARP-type [IPR001510] 0.4038274408044088 0.6161865188857699 0.5377714248834748 1.0 0.5799998968591403 2 P49916 1 +S1 domain [IPR003029] 0.505103712665322 0.6100651734192016 0.541818635637819 1.0 0.5838583130453481 7 Q14562,Q9NP64,P62487,P05198 4 +DNA2/NAM7 helicase, helicase domain [IPR041677] 0.4544625511199747 0.5909127927944422 0.5545788539610546 1.0 0.5958007912477017 3 P42694 1 +DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134] 0.4519792342634708 0.5809078257366226 0.5613025777650498 1.0 0.6009466874779991 3 Q07864,P28340 2 +DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133] 0.4519792342634708 0.5809078257366226 0.5613025777650498 1.0 0.6009466874779991 3 Q07864,P28340 2 +Tudor domain [IPR002999] 0.467552868901089 0.5779536844331784 0.5632953892006805 1.0 0.602820636053763 9 Q14739,Q15047 2 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.500804984124847 0.5524954248444427 0.5806089681405833 1.0 0.6184206918583933 5 P20020,P23634,P98194 3 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.500804984124847 0.5524954248444427 0.5806089681405833 1.0 0.6184206918583933 5 P20020,P23634,P98194 3 +BAT2, N-terminal [IPR009738] 0.381771002270515 0.5166301021001616 0.6054143981473801 1.0 0.6434631012374463 2 Q5JSZ5 1 +Zinc finger, RanBP2-type [IPR001876] 0.4756543469337012 0.5010802185008366 0.6163146680115013 1.0 0.6539301172328604 7 Q92804,P98175 2 +RuvB-like, AAA-lid domain [IPR041048] 0.3713915017839762 0.4719445394875839 0.6369663755986139 1.0 0.6749780092660503 2 Q9Y230 1 +TIP49, P-loop domain [IPR010339] 0.3713915017839762 0.4719445394875839 0.6369663755986139 1.0 0.6749780092660503 2 Q9Y230 1 +Clp ATPase, C-terminal [IPR019489] 0.3681479078819309 0.458301472299439 0.6467358665224712 1.0 0.6850385019918463 2 Q9H078 1 +Helicase/UvrB, N-terminal [IPR006935] 0.3674991891015232 0.4555920801305744 0.648683339347726 1.0 0.6868086804167151 2 Q92900 1 +Tyrosine-specific protein phosphatase, PTPase domain [IPR000242] 0.366201751540707 0.4501928348981225 0.65257140224921 1.0 0.6906311221760476 2 P18031 1 +JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.4587394411956006 0.4422064243961888 0.6583398376004941 1.0 0.6964395047977993 7 O15372,Q6P2Q9,Q92905,O00487,O00303,P51665 6 +Rpn11/EIF3F, C-terminal [IPR024969] 0.4582927620902361 0.408953084124176 0.6825740913405782 1.0 0.7199317738959174 4 O00303,P51665,O00487 3 +Gelsolin-like domain [IPR007123] 0.456530014177561 0.4050427462173359 0.685446090204888 1.0 0.7226543597325494 6 O95487,O95486,Q15436 3 +La-type HTH domain [IPR006630] 0.4524886945932889 0.3913298045296309 0.6955534710649804 1.0 0.7323786230696914 5 Q71RC2 1 +Glutathione S-transferase, C-terminal [IPR004046] 0.3964968573628978 0.370516084631055 0.7109979942032887 1.0 0.7476907840902605 10 P78417,P28161 2 +AAA+ ATPase domain [IPR003593] 0.260169326269279 0.3570471197827936 0.7210565309406678 1.0 0.7570186515338773 53 P25205,Q03518,Q9NUT2 3 +rRNA-processing arch domain [IPR025696] 0.3425235160557903 0.3566008221607867 0.7213906619001429 1.0 0.7570186515338773 2 P42285 1 +ATP-dependent RNA helicase Ski2, C-terminal [IPR012961] 0.3425235160557903 0.3566008221607867 0.7213906619001429 1.0 0.7570186515338773 2 P42285 1 +WWE domain [IPR004170] 0.3903309539260166 0.353969108939098 0.7233620338882891 1.0 0.7584470755994461 3 Q7Z2W4,Q7Z6Z7 2 +C2 domain [IPR000008] 0.3301436323663371 0.3487798427714507 0.727254597420874 1.0 0.7615648395906877 15 Q96PU5,Q86YS7,Q96J02 3 +SH3 domain [IPR001452] 0.2868471131039236 0.3383081927802273 0.7351309503958645 1.0 0.7688478747255396 28 Q9Y5K6,Q5JRA6,Q00013,Q03001,Q9Y371,Q9UQB8,Q96PC5 7 +D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140] 0.4345991561181493 0.3378893156721883 0.7354465993955484 1.0 0.7688478747255396 4 P56545,Q13363,Q9UBQ7 3 +D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139] 0.4345991561181493 0.3378893156721883 0.7354465993955484 1.0 0.7688478747255396 4 P56545,Q13363,Q9UBQ7 3 +Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861] 0.3820961944921607 0.3274562793988142 0.7433228057048336 1.0 0.7764287794042924 3 O00469 1 +ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100] 0.4261447433745844 0.3141633111617788 0.7533970064235813 1.0 0.7862904670735814 4 P21281,P06576 2 +ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194] 0.4261447433745844 0.3141633111617788 0.7533970064235813 1.0 0.7862904670735814 4 P21281,P06576 2 +Transketolase-like, pyrimidine-binding domain [IPR005475] 0.4122156627149925 0.277098703140905 0.7817043175939029 1.0 0.8126113496811078 4 Q02218 1 +Threonyl/alanyl tRNA synthetase, SAD [IPR012947] 0.4082130471410345 0.2666284713425203 0.7897552320025725 1.0 0.8194204953081783 5 Q5JTZ9 1 +Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375] 0.4047280182651664 0.2582625529194957 0.7962042845656165 1.0 0.8257671470296715 4 Q4J6C6,P48147 2 +NOPS [IPR012975] 0.3539909149902671 0.2452834797508846 0.806236942362091 1.0 0.8354752141359559 3 Q15233,Q8WXF1 2 +CS domain [IPR007052] 0.3892681008088616 0.2380141067383061 0.8118701529797867 1.0 0.8399122764493341 7 Q15185,Q9Y2Z0,Q9UHD1 3 +Chaperone DnaJ, C-terminal [IPR002939] 0.3959295604506609 0.2371387824577213 0.8125491262482476 1.0 0.8399156456769828 4 P31689 1 +Ribosomal protein L18e/L15P [IPR021131] 0.345879299156387 0.2241301080998279 0.822656065483572 1.0 0.8475437127195027 3 P46776,Q07020 2 +Dynamin, N-terminal [IPR045063] 0.3806413193987738 0.2176315643794861 0.8277161890864368 1.0 0.8513456541451726 7 O95140,O60313,P50570 3 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.3806413193987738 0.2176315643794861 0.8277161890864368 1.0 0.8513456541451726 7 O95140,O60313,P50570 3 +Anaphase-promoting complex subunit 4, WD40 domain [IPR024977] 0.3851212183258775 0.2121825240317904 0.8319646401406815 1.0 0.854654584871791 6 Q8TEQ6,O75717,Q96J01 3 +Peptidase M16, N-terminal [IPR011765] 0.3770123078527487 0.2094186213880704 0.8341214572723334 1.0 0.8561626518493067 7 O43847 1 +Peptidase M16, C-terminal [IPR007863] 0.3770123078527487 0.2094186213880704 0.8341214572723334 1.0 0.8561626518493067 7 O43847 1 +Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.3387410772225795 0.2065153605740457 0.8363883673401464 1.0 0.8581351552652101 3 Q1KMD3,Q9BUJ2 2 +GTP binding domain [IPR006073] 0.3297948259677257 0.2032946704220893 0.8389047209416662 1.0 0.8603126701400858 11 Q969Y2,Q9NTK5,O75616,P55039,A4D1E9,P36915 6 +WHEP-TRS domain [IPR000738] 0.3790976955533972 0.1998705592439131 0.8415818161558404 1.0 0.862395875912374 4 P41250,P23381,P56192 3 +Translation initiation factor, beta propellor-like domain [IPR013979] 0.3722817267121121 0.1859823409272537 0.8524586096215674 1.0 0.8717450035044083 4 Q96J01,P55884,Q9BY44 3 +AMP-dependent synthetase/ligase [IPR000873] 0.3437050950934713 0.180672177601419 0.8566248984188709 1.0 0.8756453525778426 9 P33121,Q9P265 2 +Glutathione S-transferase, C-terminal-like [IPR010987] 0.3169571928553955 0.1727845775400157 0.8628207600491631 1.0 0.8814810492945458 11 P26640,P78417,P28161 3 +MHC class I-like antigen recognition-like [IPR011161] 0.3205344827207926 0.165935123572965 0.8682080060343678 1.0 0.8860283674061734 3 P04439 1 +Immunoglobulin C1-set [IPR003597] 0.3205344827207926 0.165935123572965 0.8682080060343678 1.0 0.8860283674061734 3 P04439 1 +Protein kinase, C-terminal [IPR017892] 0.351703348047325 0.1582111039472983 0.8742904542692029 1.0 0.8911381998004259 7 P31751 1 +AGC-kinase, C-terminal [IPR000961] 0.351703348047325 0.1582111039472983 0.8742904542692029 1.0 0.8911381998004259 7 P31751 1 +OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365] 0.3558441558441619 0.1548801692535558 0.87691578762755 1.0 0.8934478065746267 5 O43776,Q6PI48,P27694,Q15046 4 +CTLH, C-terminal LisH motif [IPR006595] 0.3519502046706231 0.1482472668940538 0.8821476303134823 1.0 0.8980421822110226 5 Q9NWU2,Q9H7D7 2 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.3250461920775186 0.1440101171430958 0.8854924805913649 1.0 0.9007096181465356 9 Q9HD20,P98194,P35670 3 +K Homology domain, type 1 [IPR004088] 0.2448868007753212 0.1420913804860928 0.8870078264721499 1.0 0.9015341861188992 22 P51114,Q9NQT5,Q13868,Q92945,Q9Y6M1 5 +Actin-depolymerising factor homology domain [IPR002108] 0.3421267571639211 0.1325524190206924 0.8945473643740367 1.0 0.9084333120236336 5 P60981,Q14019 2 +KOW [IPR005824] 0.3317104836092226 0.1179324830979185 0.9061211550448912 1.0 0.91943558834351 4 O00267,P61254,P62701 3 +SMCs flexible hinge [IPR010935] 0.3266233766233926 0.1107652683281317 0.9118024876871388 1.0 0.9233160832546748 5 Q9UQE7,Q9NTJ3,O95347,A6NHR9 4 +Glutathione S-transferase, N-terminal [IPR004045] 0.2931229970823282 0.0852394804127284 0.9320710039493588 1.0 0.941922160901669 8 P78417,P28161 2 +Elongation Factor G, domain II [IPR041095] 0.2821428571428654 0.0670424990212159 0.9465478699612592 1.0 0.953517008001078 5 Q96RP9,P13639,Q7Z2Z2,Q969S9 4 +Translation elongation factor EFG/EF2, domain IV [IPR005517] 0.2820512820512864 0.0669606580151805 0.9466130232287452 1.0 0.953517008001078 4 Q96RP9,P13639,Q969S9 3 +Zinc finger, C3HC4 RING-type [IPR018957] 0.279220779220795 0.0650431424016748 0.9481396502893208 1.0 0.954167138875985 5 P38398,O75150,Q9H000,Q8IU81 4 +SH2 domain [IPR000980] 0.2484010225484664 0.0647037268074651 0.94840989547971 1.0 0.954167138875985 10 P62993,P07947,P07948,Q7KZ85,P41240,P46109 6 +14-3-3 domain [IPR023410] 0.2559272491068595 0.0526408485587751 0.9580180696294368 1.0 0.9630541532950988 6 P27348,P61981,P62258,Q04917,P63104 5 +MPN domain [IPR037518] 0.2359441013974633 0.049161986735208 0.9607902048065448 1.0 0.9654504644903276 8 O15372,Q6P2Q9,Q7L5N1,Q92905,O00487,O00303,P51665 7 +Translational (tr)-type GTP-binding domain [IPR000795] 0.1818682031814305 0.0452147764087707 0.9639361164247952 1.0 0.9678292348271572 12 Q05639,O00178 2 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..529b8a0b2b4681ca79056088b83b8ec90e9d6ab4 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase alpha 1 catalytic subunit, C-terminal [IPR039137]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA C-terminal domain [IPR032423]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADD domain [IPR025766]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARIP4, DEXH-box helicase domain [IPR044573]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ASCH domain [IPR007374]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "ATRX, ADD domain [IPR041430]", "AWS domain [IPR006560]", "Abl Interactor 1, SH3 domain [IPR035725]", "Abl-interactor, homeo-domain homologous domain [IPR012849]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acetyl-coenzyme A synthetase, N-terminal domain [IPR032387]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase [IPR006862]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Alpha/beta hydrolase fold-3 [IPR013094]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAAT/Acyl-CoA thioester hydrolase C-terminal [IPR014940]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BARD1, Zinc finger, RING-type [IPR039503]", "BAT2, N-terminal [IPR009738]", "BCAS3 domain [IPR022175]", "BCL-6 corepressor, PCGF1 binding domain [IPR032365]", "BCL-6 corepressor, non-ankyrin-repeat domain [IPR031628]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BR140-related, PWWD domain [IPR035502]", "BRCA1, serine-rich domain [IPR025994]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BRPF2, PHD domain [IPR042009]", "BRPF2, ePHD domain [IPR042004]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-trefoil DNA-binding domain [IPR015350]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin/lipoyl attachment [IPR000089]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Bud22 domain [IPR015158]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBF1-interacting co-repressor CIR, N-terminal domain [IPR019339]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCDC93, coiled-coil domain [IPR019159]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-C, middle DNMT3B-binding domain [IPR028931]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COG complex component, COG2, C-terminal [IPR024603]", "COMM domain [IPR017920]", "COMMD1 N-terminal domain [IPR033776]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COQ9 [IPR013718]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRAL/TRIO, N-terminal domain [IPR011074]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centrosomal CEP44 domain [IPR029157]", "Chaperone DnaJ, C-terminal [IPR002939]", "Checkpoint kinase 1, catalytic domain [IPR034670]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain [IPR041715]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Classical Protein Kinase C alpha, catalytic domain [IPR034663]", "Classical protein kinase C beta, catalytic domain [IPR034664]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Conserved oligomeric Golgi complex, subunit 2, N-terminal [IPR024602]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEK, C-terminal [IPR014876]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIRP domain [IPR033471]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein Rad51-like, C-terminal [IPR013632]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA recombination and repair protein RecA-like, ATP-binding domain [IPR020588]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase 3-like, TOPRIM domain [IPR034144]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IA, DNA-binding domain [IPR003602]", "DNA topoisomerase, type IA, central [IPR013497]", "DNA topoisomerase, type IA, domain 2 [IPR003601]", "DNA topoisomerase, type IA, zn finger [IPR013498]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dehydrogenase, E1 component [IPR001017]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF1977, DnaJ-like [IPR015399]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3528, homeobox protein, eukaryotic [IPR021918]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF3699 [IPR022168]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4171 [IPR025228]", "Domain of unknown function DUF4195 [IPR025243]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4477 [IPR027951]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF4757 [IPR031865]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drought induced 19 protein type, zinc-binding domain [IPR008598]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EXOG, C-terminal [IPR041003]", "EXPERA domain [IPR033118]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enhancer of polycomb-like, N-terminal [IPR019542]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst complex component Sec3, C-terminal [IPR019160]", "Exocyst complex component Sec3, PIP2-binding N-terminal domain [IPR028258]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM192A/Fyv6, N-terminal [IPR019331]", "FAM3C (ILEI) domain [IPR039475]", "FAM69, protein-kinase domain [IPR022049]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FLYWCH-type zinc finger-containing protein, N-terminal [IPR029279]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferritin-like diiron domain [IPR009040]", "Ferritin/DPS protein domain [IPR008331]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Ferrodoxin-fold anticodon-binding domain [IPR005121]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Follistatin-like, N-terminal [IPR003645]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCF, C-terminal [IPR022783]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPI ethanolamine phosphate transferase 2, C-terminal [IPR045687]", "GPI ethanolamine phosphate transferase 2, N-terminal [IPR037674]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "Gid-type RING finger domain [IPR044063]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucose-methanol-choline oxidoreductase, C-terminal [IPR007867]", "Glucose-methanol-choline oxidoreductase, N-terminal [IPR000172]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyl transferase, family 28, C-terminal [IPR007235]", "Glycosyltransferase 2-like [IPR001173]", "Glycosyltransferase subfamily 4-like, N-terminal domain [IPR028098]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Groucho/TLE, N-terminal Q-rich domain [IPR005617]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Heavy metal-associated domain, HMA [IPR006121]", "Heavy metal-associated domain, copper ion-binding [IPR006122]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "HhH-GPD domain [IPR003265]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histidyl-anticodon-binding [IPR033656]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homeobox domain, metazoa [IPR020479]", "Homocysteine-binding domain [IPR003726]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "Hpc2-related domain [IPR014840]", "HuR, RNA recognition motif 2 [IPR034996]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I/LWEQ domain [IPR002558]", "IF2a, S1-like domain [IPR044126]", "IFT81, calponin homology domain [IPR041146]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Inhibitor of growth protein, N-terminal histone-binding [IPR024610]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrator complex subunit 5, C-terminal [IPR029444]", "Integrator complex subunit 5, N-terminal [IPR029445]", "Integrin alpha-2 [IPR013649]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KAP family P-loop domain [IPR011646]", "KASH domain [IPR012315]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KMT2B, ePHD domain [IPR041959]", "KOW [IPR005824]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore assembly subunit CENP-C, N-terminal domain [IPR028052]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIN-9, C-terminal [IPR045831]", "LIS1 homology motif [IPR006594]", "LKB1 serine/threonine kinase interacting protein 1, N-terminal [IPR031782]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "LYRM2, LYR domain [IPR045293]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipid desaturase domain [IPR019547]", "Little elongation complex subunit 2 , C-terminal [IPR019535]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lunapark domain [IPR019273]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "MABP domain [IPR023341]", "MAGE homology domain [IPR002190]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MYST, zinc finger domain [IPR040706]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Mediator complex, subunit Med12 [IPR019035]", "Mediator complex, subunit Med12, LCEWAV-domain [IPR021990]", "Mediator complex, subunit Med12, catenin-binding [IPR021989]", "Mediator complex, subunit Med25, NR box [IPR021406]", "Mediator complex, subunit Med25, PTOV domain [IPR021394]", "Mediator complex, subunit Med25, synapsin 1 [IPR021397]", "Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain [IPR021419]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "MgsA AAA+ ATPase C-terminal [IPR021886]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Mif2/CENP-C cupin domain [IPR025974]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondria fission protein Fis1, cytosolic domain [IPR033745]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdenum cofactor synthesis C-terminal [IPR010505]", "Molybdopterin cofactor biosynthesis C (MoaC) domain [IPR002820]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Myb domain [IPR017930]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myotubularin-like phosphatase domain [IPR010569]", "Myotubularin-related 12-like C-terminal domain [IPR022587]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-CoR, GPS2-interacting domain [IPR031557]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-acetyltransferase ESCO, acetyl-transferase domain [IPR028009]", "N-acetyltransferase ESCO, zinc-finger [IPR028005]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase intermediate-associated protein 30 [IPR013857]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NCBP2, RNA recognition motif [IPR034148]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, C-terminal [IPR001075]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NP60, PWWP domain [IPR035501]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nischarin, PX domain [IPR037904]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear hormone receptor, ligand-binding domain [IPR000536]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear protein 96 [IPR021967]", "Nuclear speckle splicing regulatory protein 1, N-terminal [IPR018612]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar 27S pre-rRNA processing, Urb2/Npa2, C-terminal [IPR018849]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PB1 domain [IPR000270]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K p85 subunit, C-terminal SH2 domain [IPR035020]", "PI3K p85 subunit, N-terminal SH2 domain [IPR035022]", "PI3K regulatory subunit p85-related , inter-SH2 domain [IPR032498]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PINIT domain [IPR023321]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLD-like domain [IPR032803]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKAA1, UBA-like autoinhibitory domain [IPR028797]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palmitoyltransferase, DHHC domain [IPR001594]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Patatin-like phospholipase domain [IPR002641]", "Patatin-like phospholipase domain containing protein 8-like [IPR045217]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 3-kinase regulatory subunit beta, SH3 domain [IPR035586]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Plus-3 domain [IPR004343]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Pop1, N-terminal [IPR009723]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein OS9-like domain [IPR012913]", "Protein RED, C-terminal [IPR012492]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein furry, C-terminal [IPR045842]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAD51 interacting motif [IPR031419]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM40, RNA recognition motif 1 [IPR034147]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM8, RNA recognition motif [IPR033744]", "RBP-J/Cbf11/Cbf12, DNA binding [IPR015351]", "RBP-Jkappa, IPT domain [IPR038007]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING finger and SPRY domain-containing protein 1, SPRY domain [IPR035774]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 2-O ribose methyltransferase, substrate binding [IPR013123]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II elongation factor ELL, N-terminal [IPR019464]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RQC domain [IPR018982]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rad18, zinc finger UBZ4-type [IPR006642]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad51/DMC1/RadA [IPR033925]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap1 Myb domain [IPR015010]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rhodanese-like domain [IPR001763]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal RNA-processing protein 7, C-terminal domain [IPR024326]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ricin B, lectin domain [IPR000772]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rrp7, RRM-like N-terminal domain [IPR040447]", "Rrp7A, RNA recognition motif [IPR034890]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SCAF8, RNA recognition motif [IPR034370]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD2/Set2, SET domain [IPR044437]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGF29 tudor-like domain [IPR010750]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMYD3, SET domain [IPR044420]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX2, PX domain [IPR037918]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPOP, C-terminal BACK domain [IPR034089]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAR protein, homodimerisation region [IPR032377]", "STARD11, START domain [IPR041952]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Scaffold protein Nfu/NifU, N-terminal [IPR014824]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine proteases, trypsin domain [IPR001254]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set2 Rpb1 interacting domain [IPR013257]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein LSm5 [IPR033871]", "Sm-like protein Lsm3 [IPR034105]", "Sm-like protein Lsm4 [IPR034101]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromal interaction molecule 1, SAM domain [IPR037609]", "Stromal interaction molecule, Orai1-activating region [IPR032393]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfatase-modifying factor enzyme [IPR005532]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA element modulatory factor 1, TATA binding [IPR022091]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG, PB1 domain [IPR034857]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TGS [IPR004095]", "THAP-type zinc finger [IPR006612]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRC8 N-terminal domain [IPR025754]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRIM27, PRY/SPRY domain [IPR035791]", "TRIM4, PRY/SPRY domain [IPR035829]", "TROVE domain [IPR008858]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Target SNARE coiled-coil homology domain [IPR000727]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere repeat-binding factor, dimerisation domain [IPR013867]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Telomeric repeat-binding factor 2, Rap1-binding domain [IPR031902]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine synthase, N-terminal [IPR029144]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor 20, ePHD domain [IPR041972]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Lyn, SH2 domain [IPR035852]", "Tyrosine-protein kinase Lyn, SH3 domain [IPR035748]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC2, UBA domain [IPR041928]", "UBX domain [IPR001012]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UMA domain [IPR023340]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "UVR domain [IPR001943]", "Ubinuclein middle domain [IPR026947]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VIP36, lectin domain [IPR035664]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WRNIP1, ubiquitin-binding domain [IPR040539]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C2HC5-type [IPR009349]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FCS-type [IPR012313]", "Zinc finger, FLYWCH-type [IPR007588]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc finger, nuclear hormone receptor-type [IPR001628]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cDENN domain [IPR001194]", "dDENN domain [IPR005112]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA splicing factor Cwf21 domain [IPR013170]", "p21 activated kinase binding domain [IPR033923]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNase Z endonuclease [IPR027794]", "uDENN domain [IPR005113]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTN1", "ACTN4", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "APLP2", "APMAP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL2", "ARL3", "ARL8A", "ARL8B", "ARMC10", "ARMCX3", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATP7A", "ATP7B", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAP18", "BARD1", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS3", "BCKDHA", "BCKDHB", "BCOR", "BCS1L", "BIRC6", "BLM", "BLVRA", "BMI1", "BMS1", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "C1orf35", "C2CD5", "C3orf58", "CACYBP", "CAD", "CALU", "CAMK2G", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASK", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC93", "CCNB1", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC34", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPV", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHORDC1", "CHP1", "CHRAC1", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLIC1", "CLPB", "CLPX", "CLTC", "CLUH", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNPY2", "COA3", "COG2", "COIL", "COL4A3BP", "COLEC12", "COMMD1", "COMMD10", "COMMD5", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC25", "CWF19L1", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCTN1", "DCUN1D5", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "EARS2", "ECE1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMC8", "EMD", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESCO2", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM192A", "FAM208A", "FAM208B", "FAM3C", "FAM49B", "FAM8A1", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FBXO22", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDE1", "GDPD1", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGB1", "GORASP2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPI", "GPR89B", "GPS1", "GPT2", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F2", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HELLS", "HELZ", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGXB4", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA4", "HSPA4L", "HSPB1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "IARS", "IARS2", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS11", "INTS14", "INTS3", "INTS5", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "IVD", "IWS1", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1147", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LETMD1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LRRC8C", "LSM12", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "M6PR", "MACF1", "MAEA", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBD3", "MBNL1", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED25", "MEPCE", "METTL7B", "MFN1", "MFN2", "MFSD10", "MFSD8", "MGME1", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPHOSPH8", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRM3", "MRPL11", "MRPL12", "MRPL15", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCBP1", "NCBP2", "NCEH1", "NCKIPSD", "NCL", "NCLN", "NCOR1", "NCSTN", "NDUFA10", "NDUFA2", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFE", "NENF", "NEPRO", "NES", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NTHL1", "NTPCR", "NUB1", "NUBP1", "NUCB1", "NUCB2", "NUDC", "NUDT1", "NUDT12", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NVL", "NXF1", "NXN", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAXBP1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDZD8", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF3", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP4R1", "PPP5C", "PPP6C", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2B", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPMT1", "PTPN1", "PTPN9", "PUF60", "PUM3", "PUS1", "PWP2", "PWWP2A", "PYCR1", "PYCR2", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RAC1", "RACGAP1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAI1", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOX1", "RIPK1", "RMND1", "RNASEH2A", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPEP", "RNPS1", "RP2", "RPA1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRP12", "RRP7A", "RSF1", "RSL24D1", "RSPRY1", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SC5D", "SCAF11", "SCAF8", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A2", "SLC27A4", "SLC2A1", "SLC37A4", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMU1", "SMYD3", "SNAP23", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPC25", "SPECC1L", "SPEN", "SPOP", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK11IP", "STK26", "STOM", "STOML2", "STRBP", "STRN", "STRN4", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THNSL1", "THOC1", "THOC2", "THOC3", "THOP1", "THYN1", "TIAL1", "TIMELESS", "TIMM10", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TKT", "TLCD1", "TLE3", "TLN1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED8", "TMED9", "TMEM201", "TMEM205", "TMEM97", "TMF1", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOX4", "TP53", "TP53BP1", "TPBG", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMT1L", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TST", "TTC4", "TTF1", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBFD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCRC1", "UQCRC2", "URB1", "URB2", "UROD", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS16", "VPS29", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WASHC4", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WRNIP1", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YBX1", "YBX3", "YES1", "YIPF4", "YKT6", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZCCHC17", "ZCCHC3", "ZCCHC8", "ZDHHC20", "ZEB2", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF148", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF644", "ZPR1", "ZRANB2", "ZYX"], "leading_proteins": ["AARS2", "ABCB8", "ACADM", "ACSL1", "ADD3", "AFDN", "AIFM1", "AKT2", "ALDH7A1", "ALG1", "ANK3", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3M1", "ASNS", "ATAD3B", "ATP13A1", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5B", "ATP6V1B2", "ATP7B", "BAG6", "BAIAP2", "BRCA1", "BRD3", "BZW2", "C2CD5", "CAD", "CALU", "CASK", "CD2AP", "CHORDC1", "CHP1", "CKAP5", "CLPB", "COL4A3BP", "COPA", "COPG1", "COPS2", "COPS4", "COPS5", "COPS6", "COTL1", "CRKL", "CSE1L", "CSK", "CTBP1", "CTBP2", "CTPS1", "CTPS2", "CYB5D2", "CYFIP2", "DARS2", "DCTN1", "DHX8", "DIP2B", "DKC1", "DNAJA1", "DNM2", "DRG2", "DST", "DSTN", "DUSP9", "EEF1A2", "EEF2", "EFL1", "EHMT2", "EIF2A", "EIF2D", "EIF2S1", "EIF3B", "EIF3E", "EIF3F", "EIF3H", "EIF3L", "EIF3M", "EMD", "EPB41L3", "ERAL1", "EXOSC2", "EXOSC3", "FAM49B", "FARP1", "FKBP10", "FKBP14", "FKBP2", "FKBP9", "FOXRED1", "FXR1", "GARS", "GEMIN5", "GFM1", "GFM2", "GID8", "GIGYF2", "GINS4", "GMPS", "GNL1", "GNPAT", "GPS1", "GRB2", "GRHPR", "GSR", "GSTM2", "GSTO1", "GTPBP1", "GTPBP10", "GTPBP3", "HELZ", "HLA-A", "HLTF", "HNRNPAB", "HNRNPF", "HNRNPUL1", "HNRNPUL2", "HUWE1", "IARS2", "IDH2", "IGF2BP2", "IPO11", "IPO5", "IPO7", "IPO9", "IQGAP2", "IRF2BP1", "ITCH", "KARS", "KDM2A", "KHSRP", "KMT2A", "LARP4", "LBR", "LEMD2", "LIG3", "LMAN2", "LPCAT2", "LYN", "MAPRE2", "MARS", "MCM3", "MFN2", "MIA2", "MIA3", "MKRN2", "MON2", "MOV10", "MPP1", "MPRIP", "MTMR12", "MTOR", "MTR", "NAE1", "NARS", "NAXE", "NCLN", "NDUFB9", "NEDD4L", "NEFL", "NONO", "NPEPPS", "NRDC", "NSUN2", "NSUN4", "NUB1", "NUCB2", "NUP155", "OCLN", "OGDH", "OLA1", "OPA1", "OSBPL6", "OSBPL8", "P3H1", "PABPC4", "PCID2", "PHF10", "PHRF1", "PLOD2", "PM20D2", "POLD1", "POLD2", "POLE", "POLE2", "POLR1C", "POLR2G", "PPAT", "PREP", "PREPL", "PRKAA1", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2B", "PSMD11", "PSMD14", "PSMD6", "PSMD7", "PSPC1", "PTGES3", "PTPN1", "RBM10", "RBM23", "RBM3", "RBM6", "RCN2", "REPS1", "RNF40", "RPA1", "RPL18", "RPL26", "RPL27A", "RPS4X", "RSPRY1", "RTN1", "RUVBL2", "SAE1", "SDF4", "SEC23A", "SEC24A", "SEC24B", "SETDB1", "SH3GLB1", "SKIV2L2", "SLIT2", "SMARCD2", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMYD3", "SNX2", "SPOP", "SRSF7", "SUCLG1", "SUGT1", "SUPT5H", "SUPT6H", "SYNGR2", "TAF15", "TAP1", "TBC1D4", "TBCB", "TBCE", "TBL1XR1", "THOC3", "THOP1", "TMPO", "TNPO1", "TRIM27", "TUBB", "TUBB6", "UBA6", "UBE2J1", "UBE2O", "UBE2S", "UBE3A", "UBQLN4", "UBR4", "UBR5", "UHRF1", "UNC119", "UPF1", "USP36", "USP47", "USP48", "USP5", "VAMP7", "VARS1", "WARS", "WDHD1", "WDR26", "XPO5", "XPO7", "XPOT", "YBX3", "YES1", "YME1L1", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3HAV1", "ZCCHC17"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..60585e7ac6b70aeb248fa8f51087960d228b063c --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "14-3-3 protein [IPR000308]", "1": "Heat shock protein 70 family [IPR013126]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..c22a731cea70e2bba0c867cfadf018f243717407 --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c006e10d6739fd71da6dce87e2d49cf21c41f7bf7c2f851a7588a2750f9d819c +size 140514 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..d916e96257a8f24cf34df51904471d3bf57e4a8a --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6628763611d72ea74a80371b0a0f23fefeebed514ddf45ff55f07830f1404544 +size 150272 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..72854db0818db027c9868885aee9495a8283b7e2 --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e81ba9874e52a9685c6082e629c680753d58e212b5743b2f35ddc408ffa30d9b +size 846060 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2be5be49a2733a4f23997e0033dd5d0bf3fc8658 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 2382, + "title": "Average number of proteins per term", + "value": 1.2879932829554996 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..edb6f035c7f9d56d6f5671c0266f300033ffbaaf --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..09b61123bfd269330c7499064cd733708466cf46 --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,99 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Myotubularin family [IPR030564] 0.9516704508595516 3.280638126055131 0.001035725367636 0.9152776912453046 0.0035193977542213 2 Q9C0I1 1 +Haem oxygenase [IPR002051] 0.938371715861172 3.2230639150371014 0.001268272507664 0.9513421670008848 0.0040334113661625 2 P09601 1 +Haem oxygenase-like [IPR016053] 0.938371715861172 3.2230639150371014 0.001268272507664 0.9513421670008848 0.0040334113661625 2 P09601 1 +Isocitrate dehydrogenase NADP-dependent [IPR004790] 0.9250729808627922 3.1650819674929274 0.0015503926810416 0.9751749276881724 0.0045933275699516 2 P48735 1 +Cleft lip and palate transmembrane 1 [IPR008429] 0.9120986052546204 3.10811624306742 0.0018828399519299 0.9887698400874876 0.0052332844404867 2 Q96KA5 1 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.9120986052546204 3.10811624306742 0.0018828399519299 0.9887698400874876 0.0052332844404867 2 Q96KA5 1 +Tetraspanin/Peripherin [IPR018499] 0.9075575737917564 3.08808448072181 0.0020145119389769 0.9917982466585412 0.0054966408231879 2 O60637 1 +Tetraspanin, animals [IPR000301] 0.9075575737917564 3.08808448072181 0.0020145119389769 0.9917982466585412 0.0054966408231879 2 O60637 1 +Integral membrane protein EMC3/TMCO1-like [IPR002809] 0.9039896204995084 3.0723109132954325 0.00212408357865 0.9936857618848164 0.0056885946872571 2 Q9P0I2 1 +Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699] 0.9017191047680788 3.0622574121647936 0.0021967445368136 0.9946912629213432 0.0058269994283853 2 Q9NQT5 1 +Synaptobrevin [IPR001388] 0.8997729484268558 3.053630336531458 0.0022609048625983 0.9954451951778522 0.0059494818572858 2 P51809 1 +Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311] 0.8991242296464445 3.050752633781362 0.0022826855283537 0.99567599090912 0.0059882785556593 2 P33121 1 +E3 ubiquitin-protein ligase, SMURF1 type [IPR024928] 0.8919883230619481 3.0190313560213324 0.0025358428433672 0.9976375341396448 0.0064465076338322 2 Q96PU5 1 +Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101] 0.8627959779435578 2.887978762973368 0.0038772604953567 0.9999042323292062 0.0086395084190269 2 P49006 1 +AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752] 0.858254946480699 2.867405337995882 0.0041385258969444 0.999948730979218 0.0090440079692858 2 Q96ES6 1 +Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550] 0.8566331495296777 2.8600453448695324 0.0042358043739592 0.9999593745370784 0.0091975259970563 2 Q96KQ7 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.8556600713590603 2.8556262258506218 0.0042952045642215 0.9999647559167056 0.0092841899019742 2 Q9Y487 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.8556600713590603 2.8556262258506218 0.0042952045642215 0.9999647559167056 0.0092841899019742 2 Q9Y487 1 +ABC transporter Tap-like [IPR013305] 0.8306843983133231 2.7413955565519363 0.0061178807344708 0.9999995515873172 0.0121439932579246 2 Q03518 1 +Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284] 0.8151151475835161 2.669394441380922 0.0075988154188508 0.9999999871445684 0.0144113751774158 2 O15228 1 +ER lumen protein retaining receptor [IPR000133] 0.803762568926363 2.6165064473234847 0.0088834686655356 0.9999999994123984 0.0162772479702353 2 P24390 1 +TAF15/EWS/TLS family [IPR034870] 0.7966266623418656 2.5830946276519384 0.0097918461952624 0.9999999999338516 0.0174712941101985 2 Q92804 1 +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.7849497242945075 2.528140196927217 0.0114668552497441 0.9999999999988276 0.0198792206731371 2 O60830 1 +Cytoplasmic FMR1-interacting [IPR008081] 0.7833279273434857 2.5204800463505426 0.0117194882658997 0.9999999999993622 0.0201692674911852 2 Q96F07 1 +Phosphatidyl serine synthase [IPR004277] 0.7800843334414537 2.5051395357595467 0.0122403093586735 0.9999999999998184 0.0207666786982624 2 Q9BVG9 1 +ELL/occludin family [IPR031176] 0.7697048329549032 2.4558687196595534 0.014054448982526 0.9999999999999976 0.0231519346309661 2 Q16625 1 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.7680830360038833 2.448145206903454 0.014359377259455 0.9999999999999988 0.0235564990578662 2 Q5T9A4 1 +Microtubule-associated protein RP/EB [IPR027328] 0.7658125202724512 2.4373209608444006 0.0147965394788902 0.9999999999999996 0.0241572015344185 2 Q15555 1 +Adaptor protein complex AP-2, alpha subunit [IPR017104] 0.7632176451508209 2.4249342123148425 0.0153111610828151 1.0 0.0247934641055511 2 O95782 1 +Bax inhibitor 1-related [IPR006214] 0.7560817385663234 2.3907816873297825 0.0168125466011321 1.0 0.0266627736377475 2 Q9H3K2 1 +Peptidase M3A/M3B [IPR045090] 0.8564190972011221 2.3788212039495304 0.0173680979606922 1.0 0.0272894520728027 3 P52888 1 +26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585] 0.7457022380797921 2.340872625476929 0.0192387294634814 1.0 0.0295595316792004 2 Q13098 1 +Nucleosome assembly protein (NAP) [IPR002164] 0.7418099253973317 2.322085770654658 0.0202283177115281 1.0 0.0306513058453307 2 P55209 1 +Aminopeptidase N-type [IPR034016] 0.8413264566455723 2.3144683367155685 0.0206420461501088 1.0 0.0311395528369597 3 P55786 1 +Tricarboxylate/iron carrier [IPR004686] 0.8314979597107338 2.272318974500228 0.0230672515815304 1.0 0.0339174032513614 3 Q6P4A7 1 +Glutathione S-transferase, Mu class [IPR003081] 0.7236457995458901 2.2339044404365667 0.0254893613381872 1.0 0.036558668074363 2 P28161 1 +Prenylated rab acceptor PRA1 [IPR004895] 0.8223722103184274 2.23301336839145 0.0255480628055022 1.0 0.036615815645431 3 Q9UI14 1 +CTP synthase [IPR004468] 0.7174829711320041 2.203796287485005 0.0275386737953826 1.0 0.038930042124986 2 P17812 1 +Peptidase S9A, prolyl oligopeptidase [IPR002470] 0.7090496269866975 2.162441473552452 0.0305841637117065 1.0 0.0424707283088968 2 P48147 1 +Ribose-phosphate pyrophosphokinase [IPR005946] 0.7012650016217927 2.124110925876464 0.0336608691073117 1.0 0.0457608179226055 2 Q14558 1 +ADP-ribosylation factor-like protein 2/3 [IPR044612] 0.6921829386960745 2.079203687643443 0.0375986328677291 1.0 0.0501455450677104 2 P36405 1 +Peptidase M20 [IPR002933] 0.6753162504054406 1.9952764669118088 0.0460127350920278 1.0 0.0592445053995731 2 Q8IYS1 1 +HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380] 0.7540643470170396 1.9337526006120127 0.0531435531292434 1.0 0.066555175370062 3 Q5TFE4 1 +Chaperone DnaJ [IPR012724] 0.6539085306519612 1.8877984161314345 0.0590530179127066 1.0 0.0718775108165903 2 P31689 1 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.6539085306519612 1.8877984161314345 0.0590530179127066 1.0 0.0718775108165903 2 P31689 1 +Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515] 0.6519623743107363 1.877976657471527 0.0603843584210759 1.0 0.0731615166627684 2 Q13310 1 +Exportin-1/5 [IPR045065] 0.6399610768731734 1.8172289774862067 0.0691820596936312 1.0 0.0818242326342079 2 Q9HAV4 1 +AP-1/2/4 complex subunit beta [IPR016342] 0.6347713266298944 1.7908662861630895 0.0733147549818253 1.0 0.0860682554319713 2 P63010 1 +Mitochondrial carrier UCP-like [IPR002030] 0.6312033733376573 1.7727102910118937 0.0762767249652363 1.0 0.0887597258755216 2 Q9H2D1 1 +Dynamin [IPR022812] 0.7131732641142015 1.750644440807908 0.0800071751664572 1.0 0.0925580821983978 3 O60313,P50570 2 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.709012331026452 1.731864572244281 0.0832976778792251 1.0 0.095945391058179 3 P28074 1 +P-type ATPase, subfamily IIB [IPR006408] 0.6227700291923406 1.7296968239037895 0.0836844564661092 1.0 0.0962512676495761 2 P20020 1 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.7924662968473756 1.727143619210488 0.0841418735119097 1.0 0.0966840051641914 5 P55786 1 +Proteasome B-type subunit [IPR023333] 0.7641269892033888 1.706566980465709 0.087902566836707 1.0 0.1001357791511411 7 P20618,P28070,P49721,P28074 4 +ClpA/B family [IPR001270] 0.6026597469996707 1.6266018037402588 0.1038216959972357 1.0 0.1151318807567111 2 Q9H078 1 +Importin beta family [IPR040122] 0.7662199904722455 1.6084140840061203 0.1077445191121384 1.0 0.1188732952872227 4 Q92973 1 +Calponin/LIMCH1 [IPR001997] 0.5815763866363861 1.5178335145323654 0.1290563739516161 1.0 0.1387239543108076 2 Q99439 1 +Clathrin adaptor, mu subunit [IPR001392] 0.6596365996106425 1.5073032902323626 0.1317329346224078 1.0 0.140838352904208 3 Q9Y2T2,Q96CW1 2 +G-protein alpha subunit, group I [IPR001408] 0.652822842310187 1.4761123336491633 0.1399137384240543 1.0 0.1488497208245187 3 P63096,P08754 2 +Proteasome, subunit alpha/beta [IPR001353] 0.5456179213732546 1.4597439482013137 0.1443604585904503 1.0 0.1534433790104652 14 P28070,P49721,P28074 3 +AP complex subunit beta [IPR026739] 0.6349772874756741 1.394269826835852 0.1632361388713494 1.0 0.1732747249516731 3 O00203,P63010 2 +Profilin1/2/3, vertebrate [IPR005454] 0.5569250729808544 1.3900082780350131 0.1645263636484357 1.0 0.1744111251493431 2 P35080 1 +Profilin [IPR005455] 0.5569250729808544 1.3900082780350131 0.1645263636484357 1.0 0.1744111251493431 2 P35080 1 +Tubulin [IPR000217] 0.6304347826086956 1.3734110658166792 0.1696245915837879 1.0 0.1795759009567035 3 P07437,Q9BUF5 2 +Beta tubulin [IPR002453] 0.6304347826086956 1.3734110658166792 0.1696245915837879 1.0 0.1795759009567035 3 P07437,Q9BUF5 2 +Ezrin/radixin/moesin-like [IPR000798] 0.6642361608498303 1.354860730640569 0.1754619331005695 1.0 0.1856731784298341 8 Q9Y2J2,Q9Y4F1 2 +Peptidase, FtsH [IPR005936] 0.5465455724943176 1.3360606208594683 0.1815294598901276 1.0 0.1917530702697489 2 Q96TA2 1 +Ribosomal protein L14P [IPR000218] 0.5410314628608448 1.3073878170664417 0.1910810328396779 1.0 0.2013960266478375 2 Q6P1L8 1 +ADF/Cofilin [IPR017904] 0.5989769637254526 1.2288854961321798 0.2191147401505775 1.0 0.2300270211717389 3 P60981 1 +Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019] 0.6530347289840992 1.144199853232599 0.2525407639768149 1.0 0.2638386402599882 4 Q14344,P63096,P08754 3 +Initiation factor 2B-related [IPR000649] 0.5772225827384831 1.129152831682505 0.2588333676054133 1.0 0.270294205013632 3 Q14232,Q9BV20 2 +Splicing factor, RBM39-like [IPR006509] 0.504054492377543 1.1153867194129004 0.264684738128216 1.0 0.276162525721161 2 Q86U06 1 +Ubiquitin/SUMO-activating enzyme E1 [IPR000011] 0.5551960798630258 1.02873170544065 0.3036057668462053 1.0 0.3159409945948715 3 A0AVT1 1 +Bcl2-like [IPR002475] 0.6221730844227207 1.0183561702856212 0.3085087234450285 1.0 0.3204831134958822 4 Q07812 1 +Bcl-2 family [IPR026298] 0.6221730844227207 1.0183561702856212 0.3085087234450285 1.0 0.3204831134958822 4 Q07812 1 +Protein arginine N-methyltransferase [IPR025799] 0.6176566049983812 1.0000564022721472 0.3172832132353633 1.0 0.3291675147764091 4 Q86X55,O14744,O60678 3 +Oxysterol-binding protein [IPR000648] 0.6081874619605018 0.961817407557183 0.3361413322450439 1.0 0.3478230466584251 4 Q9BZF1,Q9BZF3 2 +Initiation factor 4G [IPR045208] 0.5236859182349177 0.8869111813994573 0.3751267212325004 1.0 0.3871541810987071 3 Q04637,O43432 2 +ThiF/MoeB/HesA family [IPR045886] 0.5698894619370454 0.8133323907556363 0.4160275109026334 1.0 0.4284381889191841 5 Q13564,Q9UBE0,A0AVT1 3 +RNA-binding protein 26/27 [IPR045137] 0.4372364579954516 0.7762378008170653 0.4376085905973956 1.0 0.4496909675595326 2 Q5T8P6 1 +RNA (C5-cytosine) methyltransferase [IPR023267] 0.5569688040581569 0.7626246021574045 0.4456873079948997 1.0 0.4577952426234805 5 Q08J23,Q96CB9 2 +Luc7-related [IPR004882] 0.4917470009601121 0.7468551945700312 0.4551509742890158 1.0 0.4673144917053602 3 Q9NQ29 1 +FAM98 [IPR018797] 0.4129095037301269 0.6587341876852898 0.5100664752436264 1.0 0.5212262308152372 2 Q52LJ0 1 +DNA2/NAM7-like helicase [IPR045055] 0.5299315059584732 0.6566147792161535 0.5114286434556823 1.0 0.5223940946446978 4 P42694,Q9HCE1 2 +Small GTPase Rho [IPR003578] 0.5233894082713844 0.637798049441779 0.5236051494685443 1.0 0.5346024286472665 6 Q8IXI1,P61586 2 +DNA-directed DNA polymerase, family B [IPR006172] 0.4519792342634708 0.5809078257366226 0.5613025777650498 1.0 0.5713772394172429 3 Q07864,P28340 2 +Type 1 protein exporter [IPR039421] 0.5070941998558423 0.5776068760786134 0.5635295635576023 1.0 0.5733991543759969 6 Q03518 1 +Protein PRRC2 [IPR033184] 0.381771002270515 0.5166301021001616 0.6054143981473801 1.0 0.6147046446662657 2 Q5JSZ5 1 +RuvB-like [IPR027238] 0.3713915017839762 0.4719445394875839 0.6369663755986139 1.0 0.6461899091464643 2 Q9Y230 1 +Mitochondrial carrier protein [IPR002067] 0.3486590899024057 0.3936426046392646 0.6938449216630453 1.0 0.7029938763936087 14 Q86VD7,O43808,Q8TBP6 3 +La domain containing protein [IPR045180] 0.4524886945932889 0.3913298045296309 0.6955534710649804 1.0 0.7044253265632582 5 Q71RC2 1 +ATP-dependent RNA helicase Ski2-like [IPR016438] 0.3425235160557903 0.3566008221607867 0.7213906619001429 1.0 0.7293516793914009 2 P42285 1 +Endoplasmic reticulum oxidoreductin 1 [IPR007266] 0.3340901719104771 0.3257478095711413 0.7446151685725177 1.0 0.7521939489142228 2 Q86YB8 1 +P-type ATPase [IPR001757] 0.3250461920775186 0.1440101171430958 0.8854924805913649 1.0 0.8899759868222072 9 Q9HD20,P98194,P35670 3 +Structural maintenance of chromosomes protein [IPR024704] 0.3265173644920549 0.1110099030011474 0.9116084938126584 1.0 0.9139105354637006 4 Q9UQE7,Q9NTJ3,O95347 3 +Small GTPase superfamily, ARF/SAR type [IPR006689] 0.2547505665274454 0.0693054395897607 0.9447464959847672 1.0 0.9457316134409428 10 P40616,Q8N8L6,P36405 3 +14-3-3 protein [IPR000308] 0.2559272491068595 0.0526408485587751 0.9580180696294368 1.0 0.9584204291714902 6 P27348,P61981,P62258,Q04917,P63104 5 +Heat shock protein 70 family [IPR013126] 0.2174902470741296 0.0466095678572067 0.9628244062724802 1.0 0.9628244062724802 9 P0DMV9,O95757,P54652,Q92598,P11142,P38646,Q9Y4L1,P34932 8 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9f8eba22f2046520901bda50e01a50bec6b748c7 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1-Cys peroxiredoxin [IPR045020]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-oxoisovalerate dehydrogenase subunit alpha [IPR034616]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S26 [IPR026140]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-keto-steroid reductase [IPR042829]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "4-aminobutyrate aminotransferase, eukaryotic [IPR004631]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "50S ribosomal protein uL4 [IPR013005]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABI family [IPR028457]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 10 [IPR042951]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1 complex subunit sigma [IPR044733]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit ATP5MJ, mitochondrial [IPR012574]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase ARIP4-like [IPR044574]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATR-interacting protein [IPR033349]", "Abl interactor 1 [IPR028456]", "Acetate-CoA ligase [IPR011904]", "Acetyl-coenzyme A transporter 1-like [IPR024371]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Actin family [IPR004000]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Activating signal cointegrator 1-like [IPR039128]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active regulator of SIRT1 [IPR023262]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA thioesterase, long chain [IPR016662]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A diphosphatase NUDT19 [IPR039121]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine kinase [IPR001805]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase ALAT1/2-like [IPR045088]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid beta precursor protein binding family B member 1/2/3 [IPR039576]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Anion exchange protein 2 [IPR002978]", "Anion exchange protein [IPR001717]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-10 [IPR031291]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Antigen peptide transporter 2 [IPR005293]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAK [IPR026308]", "Apoptosis regulator BAX [IPR026304]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Apyrase [IPR009283]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arylacetamide deacetylase [IPR017157]", "Arylesterase [IPR002640]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Asparaginyl endopeptidase [IPR043577]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase B [IPR028772]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BTB-kelch protein [IPR017096]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bicaudal-D protein [IPR018477]", "Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [IPR013109]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bud22/Serum response factor-binding protein 1 [IPR037393]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-alcohol phosphatidyltransferase class-II family [IPR016270]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CGG triplet repeat-binding protein 1 [IPR033375]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COG complex component, COG2 [IPR009316]", "COMM domain-containing protein 1 [IPR037351]", "COMM domain-containing protein 10 [IPR037361]", "COMM domain-containing protein 5 [IPR037357]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF complex subunit CPSF4-like [IPR045348]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase activity and apoptosis inhibitor 1 [IPR038991]", "Cat eye syndrome critical region protein 2 [IPR029614]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cationic amino acid transport permease [IPR004755]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein C/Mif2/cnp3 [IPR028386]", "Centromere protein I [IPR012485]", "Centromere protein P [IPR027801]", "Centromere protein Q [IPR025212]", "Centromere protein U [IPR025214]", "Centrosomal protein of 44kDa [IPR033603]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Choline transporter-like [IPR007603]", "Choline/ethanolamine phosphotransferase [IPR014472]", "Chondroitin N-acetylgalactosaminyltransferase [IPR008428]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin complexes subunit BAP18 [IPR037931]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homolog 2 [IPR042796]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Claspin [IPR024146]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 137 [IPR026680]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 167 [IPR028194]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 90-like [IPR024461]", "Coiled-coil domain-containing protein 93 [IPR039116]", "Coilin [IPR024822]", "Complex I intermediate-associated protein 30, mitochondrial [IPR039131]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit G2 [IPR024741]", "Conserved oligomeric Golgi complex subunit 5 [IPR019465]", "Conserved oligomeric Golgi complex subunit 6 [IPR010490]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1C [IPR027333]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-7 [IPR031223]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 1 [IPR014807]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP1/Nbp35 [IPR028601]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 16 [IPR028216]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA recombination and repair protein, RecA-like [IPR016467]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IA [IPR000380]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "DUF5568 family [IPR040419]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Dehydrogenase/reductase SDR member 4-like [IPR029511]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxynucleoside kinase [IPR002624]", "Deoxyribonuclease II [IPR004947]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dipeptidyl-peptidase 3 [IPR005317]", "Divergent protein kinase domain 2A/B [IPR020519]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 25-like [IPR044632]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [IPR039485]", "Dolichol kinase [IPR026566]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Drebrin [IPR028438]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 SUMO-protein ligase PIAS1 [IPR027227]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RING2 [IPR037937]", "E3 ubiquitin-protein ligase RNF123/RSPRY1-like [IPR045129]", "E3 ubiquitin-protein ligase UBR7 [IPR040204]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Endonuclease III-like protein 1 [IPR030841]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Ephrin receptor type-A /type-B [IPR016257]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec10-like [IPR009976]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "F-box-like/WD repeat-containing protein Ebi-like [IPR045183]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FLYWCH-type zinc finger-containing protein 1/2 [IPR040312]", "FUN14 [IPR007014]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 2 [IPR030305]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferritin [IPR001519]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fyv10 family [IPR045098]", "Fyv7/TAP26 [IPR013730]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase 2-like [IPR045130]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GOSR2/Membrin/Bos1 [IPR027027]", "GPI ethanolamine phosphate transferase 2 [IPR039527]", "GPI mannosyltransferase [IPR005599]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI transamidase subunit PIG-U [IPR009600]", "GPI-anchor transamidase [IPR028361]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "Galactokinase [IPR000705]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucose-methanol-choline oxidoreductase [IPR012132]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 13 [IPR004139]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Groucho/transducin-like enhancer [IPR009146]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "H/ACA ribonucleoprotein complex, subunit Nop10 [IPR007264]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HEXIM [IPR024872]", "HMG domain-containing protein 4 [IPR042477]", "HMG-CoA lyase [IPR043594]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 12A [IPR026685]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase XPB/Ssl2 [IPR001161]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histidine-tRNA ligase [IPR015807]", "Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit [IPR004516]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone acetyltransferases subunit 3 [IPR019340]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1 [IPR038035]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase SETD2, animal [IPR042294]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "ING family [IPR028651]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of growth protein 4/5 [IPR028638]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B alpha/beta/delta [IPR011559]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol monophosphatase-like [IPR000760]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integral membrane protein SYS1 [IPR016973]", "Integral membrane protein SYS1-related [IPR019185]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 10 [IPR026164]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 5 [IPR040316]", "Integrator complex subunit 8 [IPR038751]", "Integrin alpha chain [IPR000413]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intracellular chloride channel [IPR002946]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intraflagellar transport protein 81 [IPR029600]", "Intron Large complex component GCFC2-like [IPR012890]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KRR1 interacting protein 1 [IPR018034]", "Kelch-like ECH-associated protein 1 [IPR030563]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore Mis14/Nsl1 [IPR013950]", "Kinetochore protein Spc25 [IPR045143]", "Kintoun [IPR034727]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LIM domain only protein 7 [IPR029978]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "Las1 [IPR007174]", "Learning associated protein 18-like [IPR018784]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lipid droplet-associated hydrolase [IPR019363]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Luc7-related [IPR004882]", "Lunapark family [IPR040115]", "Lupus La protein [IPR002344]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase phosphoprotein 6 [IPR019324]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "METTL16/RlmF family [IPR010286]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MKRN-like [IPR045072]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "Macrophage migration inhibitory factor [IPR001398]", "Magnesium transporter protein 1 [IPR006844]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannose-P-dolichol utilization defect 1 protein [IPR016817]", "Mannosyltransferase ALG2 [IPR027054]", "Med25/PTOV1 [IPR045105]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med20 [IPR013921]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med27 [IPR021627]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribose-1-phosphate isomerase [IPR005251]", "Methylthiotransferase [IPR005839]", "Methyltransferase METTL16/PsiM [IPR017182]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microsomal glutathione S-transferase 1-like [IPR040162]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondria fission 1 protein [IPR016543]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial calcium uniporter regulator 1 [IPR012439]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein Mtm1-like [IPR045315]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit TIM22 [IPR039175]", "Mitochondrial import inner membrane translocase subunit Tim10 [IPR027100]", "Mitochondrial import inner membrane translocase subunit Tim29 [IPR019322]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdenum cofactor biosynthesis C [IPR023045]", "Molybdenum cofactor biosynthesis protein A [IPR013483]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 12 [IPR030576]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetylglucosaminyl phosphatidylinositol deacetylase-related [IPR003737]", "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase [IPR039516]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase 1, beta subcomplex, subunit 6 [IPR019174]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, iron-sulphur subunit 5 [IPR019342]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Nck-associated protein 1 [IPR019137]", "Nectin-2 [IPR033318]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neural cell adhesion [IPR009138]", "Neural cell adhesion molecule 1 [IPR033019]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Non-specific endonuclease [IPR040255]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nuclear MIS12/MIND complex subunit PMF1/Nnf1 [IPR007128]", "Nuclear RNA export factor [IPR030217]", "Nuclear RNA-splicing-associated protein, SR-25 [IPR019532]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 2 [IPR027157]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear hormone receptor [IPR001723]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear speckle splicing regulatory protein 1 [IPR042816]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar and spindle-associated protein 1 [IPR026756]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar protein of 40kDa [IPR037320]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase 6 [IPR037994]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "Nucleotide-sugar transporter [IPR007271]", "NudC family [IPR037898]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ODR-4-like [IPR029454]", "Occludin [IPR002958]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Oligosaccharyltransferase complex subunit OSTC [IPR042416]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 2 [IPR007220]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 6 [IPR008721]", "Origin recognition complex, subunit 6, metazoa/plant [IPR020529]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IB [IPR027256]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PDZ domain-containing protein 8 [IPR039275]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PSME3-interacting protein [IPR039845]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic antigen Ma [IPR026523]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Patatin-like phospholipase domain-containing protein 4 [IPR033902]", "Patatin-like phospholipase domain-containing protein [IPR033562]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1A, chymotrypsin family [IPR001314]", "Peptidase S1C [IPR001940]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal biogenesis factor 11 [IPR008733]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phenylalanyl-tRNA synthetase, class IIc, mitochondrial [IPR004530]", "Phorbol-12-myristate-13-acetate-induced protein 1 [IPR024140]", "Phosducin-like [IPR045037]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [IPR042165]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like [IPR044596]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phospholipase B-like [IPR007000]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Platelet-activating factor acetylhydrolase, eucaryote [IPR016715]", "Platelet-activating factor acetylhydrolase-like [IPR005065]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polycomb protein EED [IPR037352]", "Polyprenol kinase family [IPR032974]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA splicing factor [IPR022209]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable E3 ubiquitin-protein ligase makorin-2 [IPR026293]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein CIP2A [IPR042510]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM3C [IPR039219]", "Protein FAM8A1 [IPR039871]", "Protein FMC1 homologue [IPR037667]", "Protein Fyv10/E3 ubiquitin-protein transferase MAEA [IPR027714]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LCHN/Anr2 [IPR018626]", "Protein LIN-9/Protein ALWAYS EARLY [IPR010561]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein Mon2-like [IPR026829]", "Protein NCBP2AS2 [IPR042407]", "Protein NDRG3 [IPR030692]", "Protein Njmu-R1 [IPR028280]", "Protein OS-9-like [IPR045149]", "Protein PCF11-like [IPR045154]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein TFG [IPR033512]", "Protein XRP2 [IPR039093]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C, alpha/beta/gamma types [IPR014375]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF1387 [IPR009816]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF4660 [IPR029089]", "Protein of unknown function DUF719 [IPR007998]", "Protein of unknown function DUF842, eukaryotic [IPR008560]", "Protein of unknown function DUF92, TMEM19 [IPR002794]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein suppressor of sable-like [IPR045124]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein unc-119 homologue A-like [IPR032977]", "Protein virilizer [IPR026736]", "Protein-L-histidine N-pros-methyltransferase [IPR007884]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA methyltransferase [IPR003750]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAB11-binding protein RELCH [IPR040362]", "RAD51-associated protein 1 [IPR026632]", "RFT1 [IPR007594]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II elongation factor ELL [IPR031184]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein Nova-1 [IPR033086]", "RNA-binding region-containing protein RBM41/RNPC3 [IPR045164]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit Pop5/Rpp14/Rnp2-like [IPR002759]", "RNase P subunit p30 [IPR002738]", "RPA-related protein RADX [IPR040893]", "RSBN1/Dpy-21 [IPR026306]", "RZZ complex, subunit Zw10 [IPR009361]", "RZZ complex, subunit Zwilch [IPR018630]", "Rab GDI protein [IPR000806]", "Rab11-family interacting protein class I [IPR037789]", "Rab12 [IPR041830]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab35 [IPR041815]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Rab29/Rab38/Rab32 [IPR030697]", "Ras-related protein Ral [IPR028412]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulophagy receptor 1/3 [IPR043384]", "Reticulophagy regulator 3 [IPR033361]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease P protein subunit Rpp38 [IPR042848]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein 7 [IPR040446]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24e [IPR023438]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27/L41, mitochondrial [IPR019189]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome biogenesis protein Slx9-like [IPR028160]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "Ribosome-releasing factor 2, mitochondrial [IPR030851]", "RidA family [IPR006056]", "Romo1/Mgr2 [IPR018450]", "Root UVB sensitive family [IPR006968]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAGA-associated factor 29 [IPR037802]", "SAP30-binding protein [IPR012479]", "SCAMP [IPR007273]", "SERRATE/Ars2 [IPR039727]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNARE associated Golgi protein [IPR032816]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "STEEP-like [IPR029704]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BAF60B [IPR030090]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sds3-like [IPR013907]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/Arginine-related protein 53 [IPR034604]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shikimate kinase/Threonine synthase-like 1 [IPR000623]", "Shikimate kinase/gluconokinase [IPR031322]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smooth muscle protein/calponin [IPR003096]", "Snapin [IPR017246]", "Snapin/Pallidin/Snn1 [IPR028119]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium/solute symporter [IPR001734]", "Sodium:dicarboxylate symporter [IPR001991]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 12 member 9 [IPR030345]", "Solute carrier family 25 member 44 [IPR042164]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sororin protein [IPR018605]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle and kinetochore-associated protein 3 [IPR033341]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 3B subunit 5/RDS3 complex subunit 10 [IPR009846]", "Splicing factor 3B, subunit 5 [IPR017089]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Stromal interaction molecule 1 [IPR030463]", "Stromal interaction molecule [IPR037608]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, cytochrome b556 subunit [IPR014314]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit [IPR000701]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar phosphate transporter [IPR000849]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of hairless-like [IPR040159]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntaxin-3 [IPR031186]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA element modulatory factor 1 DNA binding [IPR022092]", "TB2/DP1/HVA22-related protein [IPR004345]", "TE2IP/Rap1 [IPR039595]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TREX component Tex1/THOC3 [IPR040132]", "Taxilin family [IPR026183]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Telomeric repeat-binding factor 1/2 [IPR017357]", "Telomeric repeat-binding factor 2 [IPR030657]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 15 [IPR042418]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine synthase-like [IPR004450]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A [IPR030549]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription initiation factor TAFII31 [IPR003162]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulator TACO1-like [IPR002876]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 223 [IPR026100]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 41A/B [IPR045014]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transmembrane protein TqsA-like [IPR002549]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm3 [IPR040002]", "UAA transporter [IPR013657]", "UAP56-interacting factor [IPR009782]", "UBAP2/protein lingerer [IPR022166]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "UPF0767 family [IPR031933]", "USP39 [IPR033809]", "UV excision repair protein Rad23 [IPR004806]", "UbiA prenyltransferase domain containing protein 1 [IPR026046]", "UbiA prenyltransferase family [IPR000537]", "Ubinuclein-1 [IPR026936]", "Ubiquinol-cytochrome c chaperone, CBP3 [IPR007129]", "Ubiquinol-cytochrome c chaperone/UPF0174 [IPR021150]", "Ubiquinone biosynthesis protein COQ9 [IPR012762]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin domain-containing protein UBFD1 [IPR039120]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-associated protein 1 [IPR038870]", "Ubiquitin-fold modifier-conjugating enzyme 1 [IPR014806]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised conserved protein UCP013899, metal binding [IPR016617]", "Uncharacterised protein family UPF0390 [IPR019034]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family UPF0640 [IPR028183]", "Uncharacterised protein family, TMEM59 [IPR022065]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Ureohydrolase [IPR006035]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar ATPase assembly integral membrane protein Vma21 [IPR019013]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vang-like protein [IPR009539]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "WASH complex subunit 7 [IPR027307]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "Xyloside xylosyltransferase 1 [IPR042465]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YIP1 family member 3 [IPR026637]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter Msc2-like [IPR045316]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA export factor Gle2/RAE1 [IPR037631]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein RRP36 [IPR009292]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7 [IPR028590]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-specific 2-thiouridylase [IPR004506]"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACSS1", "ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFG3L2", "AGA", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANKLE2", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEX1", "API5", "APLP2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFIP1", "ARG2", "ARHGDIA", "ARID1A", "ARID3B", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC6", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATXN2L", "AURKA", "AURKB", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAX", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCL2L13", "BCLAF1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPTF", "BRCA1", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUD23", "BUD31", "BYSL", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf35", "C1orf52", "C2CD5", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf33", "CAAP1", "CAB39", "CAD", "CALR", "CALU", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CAST", "CBR1", "CBR4", "CBX2", "CBX3", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC59", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC37", "CDC40", "CDC42", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK5RAP3", "CDKAL1", "CEBPZ", "CECR2", "CELF2", "CENPC", "CENPI", "CENPP", "CENPQ", "CENPU", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHDH", "CHERP", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHST14", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COIL", "COLGALT1", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF2", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSGALNACT2", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CWF19L1", "CXorf56", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DCAF1", "DCAF16", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DECR1", "DECR2", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAJA1", "DNAJA2", "DNAJC10", "DNAJC13", "DNAJC25", "DNAJC8", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLK", "DPM1", "DPP3", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EED", "EEF1A2", "EEF1E1", "EEF1G", "EFHD1", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2B1", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENDOD1", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESF1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAM114A2", "FAM120A", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM207A", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIS1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMC1", "FMR1", "FN3KRP", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GCAT", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDI2", "GEMIN4", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GHITM", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLS", "GLUD1", "GM2A", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRPEL1", "GRSF1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDHD5", "HEATR1", "HEBP1", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTRA2", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS10", "INTS13", "INTS14", "INTS3", "INTS5", "INTS8", "IPO4", "IPO5", "IRS4", "ISCU", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KDELR1", "KDELR3", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF5B", "KLC1", "KMT2A", "KMT2B", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LETMD1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMF2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT3", "LRPAP1", "LRPPRC", "LRRC47", "LSM12", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LZIC", "M6PR", "MACF1", "MAEA", "MAGED2", "MAGT1", "MAK16", "MAN1A2", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPST", "MPV17L2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTR", "MTX1", "MTX2", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYO18A", "NAA15", "NAA40", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NAT10", "NAXE", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF1", "NDUFB10", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NFS1", "NHP2", "NIP7", "NIPBL", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NSA2", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT19", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUSAP1", "NXF1", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH2", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PAWR", "PAXBP1", "PBRM1", "PC", "PCBD1", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PELO", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGS1", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIP4K2C", "PISD", "PITPNB", "PKM", "PKMYT1", "PLA2G15", "PLBD2", "PLEC", "PLIN3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA4", "PNPT1", "POFUT1", "POFUT2", "POLA1", "POLA2", "POLD1", "POLD2", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIE", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2B", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM23", "RBM26", "RBM27", "RBM39", "RBM45", "RBM5", "RBM6", "RBM8A", "RBPJ", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFT1", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPEP", "ROMO1", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RSRC1", "RTCB", "RTFDC1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARS", "SARS2", "SART1", "SBDS", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B5", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35A4", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLK", "SLTM", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMIM12", "SMIM4", "SMPD4", "SMU1", "SMYD3", "SNAPIN", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPOUT1", "SPR", "SPTBN1", "SPTBN2", "SQLE", "SRFBP1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF6", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SURF6", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYS1", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARS", "TARS2", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TECR", "TEFM", "TERF2", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM29", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TLE3", "TM7SF2", "TM9SF3", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM19", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM223", "TMEM230", "TMEM245", "TMEM33", "TMEM41A", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMX2", "TNPO1", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPX2", "TRABD", "TRAM1", "TRAP1", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TST", "TTC19", "TTC26", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UAP1", "UBA1", "UBA2", "UBA6", "UBAP1", "UBAP2L", "UBE3A", "UBE3C", "UBFD1", "UBIAD1", "UBN1", "UBR4", "UBR7", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC119", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRQ", "URB1", "UROD", "USMG5", "USP10", "USP14", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP3", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "WAPL", "WARS", "WARS2", "WASHC4", "WBP11", "WBP2", "WDR12", "WDR18", "WDR33", "WDR41", "WDR46", "WDR74", "WDR82", "WDR91", "WFS1", "WIPI2", "WTAP", "XAB2", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YEATS2", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YLPM1", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H14", "ZC3H8", "ZCCHC17", "ZCCHC3", "ZMPSTE24", "ZMYND8", "ZNF326", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZWILCH"], "leading_proteins": ["ACSL1", "AP2A1", "AP2B1", "AP2M1", "AP3B1", "AP3M1", "ARL1", "ARL10", "ARL3", "ATAD3B", "ATP13A1", "ATP2B1", "ATP2C1", "ATP6V0A2", "ATP7B", "BAX", "CARM1", "CLPB", "CLPTM1L", "CNN2", "CTPS1", "CYFIP2", "DNAJA1", "DNM2", "DSTN", "EHMT2", "EIF2B1", "EIF4G1", "EIF4G3", "EMC3", "EPB41L3", "ERO1B", "EXOSC3", "FAM98B", "FARP1", "GHITM", "GNA13", "GNAI1", "GNAI3", "GNPAT", "GPS1", "GSTM2", "HELZ", "HMOX1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPH1", "HYOU1", "IDH2", "KDELR1", "LARP4", "LUC7L", "MAPRE2", "MARCKSL1", "MFSD3", "MOV10", "MRI1", "MRPL14", "MTMR12", "NAE1", "NAP1L1", "NEDD4L", "NPEPPS", "NSUN2", "NSUN4", "NT5DC1", "OCLN", "OPA1", "OSBPL6", "OSBPL8", "PABPC4", "PFN2", "PM20D2", "POLD1", "POLE", "PREP", "PRMT3", "PRMT5", "PRPSAP1", "PRRC2B", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PTDSS2", "RABAC1", "RBM23", "RBM26", "RHOA", "RHOT2", "RUVBL2", "SAE1", "SFXN4", "SKIV2L2", "SLC25A17", "SLC25A32", "SLC25A40", "SLC25A42", "SMC2", "SMC3", "SMC4", "TAF15", "TAP1", "THOP1", "TIMM17B", "TNPO1", "TSPAN3", "TUBB", "TUBB6", "UBA6", "VAMP7", "XPO5", "YME1L1", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ"]} \ No newline at end of file diff --git a/interpro_homologous_superfamily/advanced/idx2term.json b/interpro_homologous_superfamily/advanced/idx2term.json new file mode 100644 index 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0000000000000000000000000000000000000000..597d18591d40ab5b7df32594ffe801b844219cae --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:39d68f5730ff13ac79382841bd2eb370d9f91adaa8f0bd74d67502a8fedc60e0 +size 283981 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c1c8c8721241659c68073a18bfadd3667e5cf663 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +FAD/NAD(P)-binding domain superfamily [IPR036188] 4 20 2.507343584618332 0.0121642405981046 5.128640776699029 19.483009708737864 1.1388517428876976 0.3148047818604211 2.42568278788952 1.8971625900564304 0.9268276914308484 0.2996934003616133 0.0412996615361356 0.1715759324473242 0.0548237001435711 0.0691213376044611 0.0401901439706117 +Ubiquitin-like domain superfamily [IPR029071] 12 33 2.457079707612643 0.0140071604431599 11.74757281553398 41.27427184466019 -0.211476259581958 0.623848045693968 5.827984791515399 5.973649110308603 0.7649250476398386 0.2908772909022708 1.0 1.0 0.148051344240397 0.2434172221614618 0.1340488417876333 +Tetratricopeptide-like helical domain superfamily [IPR011990] 28 74 2.1658588131905767 0.0303219774530807 22.856796116504853 85.5631067961165 0.5676132842696584 0.6143258973719493 7.683128498309678 5.891280215778877 0.9202004538980384 0.371378017802006 1.0 0.0091819187009941 0.0861470699703376 0.2441376965758895 0.0018780781559918 +RmlC-like jelly roll fold [IPR014710] 2 9 2.130125321239829 0.0331612683441537 2.6674757281553396 8.854368932038835 -0.0937515355609403 0.4128896377036541 1.427405289699237 1.237816484902717 1.1647229558969296 0.2931874986313249 1.0 0.0919337377678228 0.1774332758731671 0.0120645849010356 0.0715580706890916 +Cyclic nucleotide-binding-like [IPR018490] 0 5 1.9818106067482733 0.047500441893058 1.4902912621359223 4.660194174757281 -0.0126471736913758 0.4102849468515657 0.986512397936728 0.870814795980239 1.213781652340298 0.307139032821674 1.0 0.0470522829573702 0.0930016660897952 0.2191369015278419 0.3946911962196813 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..91049ac24f18b90e46b1ceb5ccad473b20bbed9f --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 943, + "title": "Average number of proteins per term", + "value": 4.693531283138919 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d2003d17864500892bb19d332b91c3ee60f85ddb --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d021b297c2edbc6a0bac0ac55fad77a6342d30bd --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,149 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +GMP phosphodiesterase, delta subunit superfamily [IPR037036] 0.9701589361011986 3.3600129029369525 0.0007793883241291 0.5206142822830719 0.0058926764640449 2 Q13432 1 +Haem oxygenase-like, multi-helical [IPR016084] 0.938371715861172 3.2230639150371014 0.001268272507664 0.6978223022442833 0.0074748810920449 2 P09601 1 +Tetraspanin, EC2 domain superfamily [IPR008952] 0.9075575737917564 3.08808448072181 0.0020145119389769 0.8506706188294344 0.010104706161996 2 O60637 1 +Class II aldolase/adducin N-terminal domain superfamily [IPR036409] 0.9007460265974684 3.0579450049244525 0.0022286047175363 0.8780226031196858 0.0108328569517361 2 Q9UEY8 1 +GINS, helical bundle-like domain superfamily [IPR036224] 0.8705806033084642 2.923129418919096 0.0034653244921512 0.962125457939476 0.013347929212828 2 Q9BRT9 1 +Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080] 0.8666882906260087 2.905572694846416 0.003665816851178 0.968671183047216 0.0136634991725727 2 P52888 1 +DNA-directed RNA polymerase, insert domain superfamily [IPR036643] 0.8361985079468044 2.766749466995616 0.0056618247559372 0.9952720925083226 0.0188660803704905 2 O15160 1 +RNA polymerase, RBP11-like subunit [IPR036603] 0.8361985079468044 2.766749466995616 0.0056618247559372 0.9952720925083226 0.0188660803704905 2 O15160 1 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.6393682577983401 2.5073435846183316 0.0121642405981046 0.9999902789521224 0.0325877241023086 20 O95831,Q9H9P8,Q8NB78,Q96CU9 4 +Ubiquitin-like domain superfamily [IPR029071] 0.5499476364574086 2.457079707612643 0.0140071604431599 0.9999983290761604 0.0356031059242583 33 Q9Y5A7,Q9NZ01,Q92575,Q96T88,Q9Y4F1,P55196,Q9Y2J2,P46379,Q9NRR5,Q9HCM4,Q96K76,P60520 12 +EB1, C-terminal domain superfamily [IPR036133] 0.7658125202724512 2.4373209608444006 0.0147965394788902 0.9999992148535076 0.0371094061930678 2 Q15555 1 +Six-hairpin glycosidase superfamily [IPR008928] 0.7641907233214322 2.429581265549942 0.0151162757072755 0.9999994218802352 0.0377107089734414 2 Q13724 1 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.8564190972011221 2.3788212039495304 0.0173680979606922 0.9999999332300908 0.0423207141522811 3 P52888 1 +Six-hairpin glycosidase-like superfamily [IPR012341] 0.8468529414749607 2.338084833802788 0.0193828478051787 0.9999999903613844 0.0458095876698835 3 O60476 1 +TRAF-like [IPR008974] 0.7427830035679429 2.3267861072075435 0.0199766521987561 0.9999999945556473 0.0465251307365146 2 O43791 1 +NAP-like superfamily [IPR037231] 0.7418099253973317 2.322085770654658 0.0202283177115281 0.9999999957266856 0.0465251307365146 2 P55209 1 +K homology domain-like, alpha/beta [IPR015946] 0.7366201751540666 2.2969765721134707 0.0216201062393319 0.9999999988816172 0.048658138863222 2 P23396 1 +K homology domain superfamily, prokaryotic type [IPR009019] 0.7366201751540666 2.2969765721134707 0.0216201062393319 0.9999999988816172 0.048658138863222 2 P23396 1 +Tetratricopeptide-like helical domain superfamily [IPR011990] 0.4199543561171657 2.1658588131905767 0.0303219774530807 0.9999999999997546 0.0631205844111592 74 Q9UJX2,Q9Y262,Q75QN2,O75153,Q99615,Q6PD62,Q9H7B4,Q9UJX3,A0AVF1,Q32P28,Q9UBV2,P13674,Q6PGP7,Q96DB5,Q9Y5A7,Q12797,Q13217,O00411,Q9UJX4,Q9Y2Z0,Q6DKK2,Q13451,P42345,O95801,Q9Y5Q9,O00231,Q9BXJ9,P49321 28 +RmlC-like jelly roll fold [IPR014710] 0.8069296053757731 2.130125321239829 0.0331612683441537 0.9999999999999846 0.0672496259108322 9 P34949,Q8IY17 2 +NET domain superfamily [IPR038336] 0.7871890594875404 2.079965787692905 0.0375286710079811 0.9999999999999998 0.0737282015844297 3 Q15059 1 +MAN1, winged-helix domain [IPR041885] 0.658773921505025 1.91231627246473 0.0558356398931998 1.0 0.0984789022855026 2 Q8NC56 1 +Mitochondrial carrier domain superfamily [IPR023395] 0.522057915754968 1.911228033889158 0.0559752827412824 1.0 0.0984789022855026 24 O43772,Q9BQT8,Q70HW3,O43808,Q9BSK2,Q8TBP6,Q86VD7 7 +Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410] 0.6539085306519612 1.8877984161314345 0.0590530179127066 1.0 0.1027435348555025 2 P31689 1 +C-type lectin fold [IPR016187] 0.7344799970793481 1.8463954070509048 0.0648348136322942 1.0 0.1103596195943203 3 Q8NBJ7 1 +CAP Gly-rich domain superfamily [IPR036859] 0.7339390006489257 1.8439731322660464 0.0651870558692642 1.0 0.1105600605840218 3 Q14203,Q99426 2 +Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037] 0.6347713266298944 1.7908662861630895 0.0733147549818253 1.0 0.122148081179967 2 P63010 1 +RmlC-like cupin domain superfamily [IPR011051] 0.8058732977277767 1.7691967057041968 0.0768610537721155 1.0 0.127157848608956 4 P34949 1 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.7924662968473756 1.727143619210488 0.0841418735119097 1.0 0.1364856714606471 5 P55786 1 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.7924662968473756 1.727143619210488 0.0841418735119097 1.0 0.1364856714606471 5 P55786 1 +Signal recognition particle, SRP9/SRP14 subunit [IPR009018] 0.6192020759000921 1.7114581284922008 0.0869965744240885 1.0 0.1395200164658427 2 P49458 1 +Zinc finger, CCHC-type superfamily [IPR036875] 0.7905573874925893 1.7072956117317493 0.087767121348133 1.0 0.1402786363242194 4 Q16629 1 +Immunoglobulin E-set [IPR014756] 0.5583069227338282 1.6208748587196269 0.1050444797609331 1.0 0.1640015636002647 15 Q13432,A6NIH7 2 +Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100] 0.663393768676926 1.5971288225232831 0.1102369945981882 1.0 0.1673969177231747 10 P11310 1 +Acyl-CoA dehydrogenase-like, C-terminal [IPR036250] 0.663393768676926 1.5971288225232831 0.1102369945981882 1.0 0.1673969177231747 10 P11310 1 +Aldehyde dehydrogenase, N-terminal [IPR016162] 0.6817806238563698 1.5536706393347224 0.1202629999870494 1.0 0.178876985785154 9 P49419 1 +Aldehyde/histidinol dehydrogenase [IPR016161] 0.6817806238563698 1.5536706393347224 0.1202629999870494 1.0 0.178876985785154 9 P49419 1 +Aldehyde dehydrogenase, C-terminal [IPR016163] 0.6817806238563698 1.5536706393347224 0.1202629999870494 1.0 0.178876985785154 9 P49419 1 +PABC (PABP) domain [IPR036053] 0.6521739130434745 1.4731398571025558 0.1407133281532249 1.0 0.2032046990022834 3 O95071,Q13310 2 +Profilin superfamily [IPR036140] 0.5569250729808544 1.3900082780350131 0.1645263636484357 1.0 0.2340095941485293 2 P35080 1 +KA1 domain/Ssp2, C-terminal [IPR028375] 0.5559519948102413 1.384952773401118 0.1660669085777586 1.0 0.2358450222723289 2 Q13131 1 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.6304347826086956 1.3734110658166792 0.1696245915837879 1.0 0.2394550746459761 3 P07437,Q9BUF5 2 +Tubulin, C-terminal [IPR023123] 0.6304347826086956 1.3734110658166792 0.1696245915837879 1.0 0.2394550746459761 3 P07437,Q9BUF5 2 +Tubulin/FtsZ, C-terminal [IPR008280] 0.6304347826086956 1.3734110658166792 0.1696245915837879 1.0 0.2394550746459761 3 P07437,Q9BUF5 2 +PUA domain superfamily [IPR036974] 0.5475186506649313 1.3411199033972308 0.1798815261421613 1.0 0.2527992237735591 2 O60832 1 +Peptidase M41-like [IPR037219] 0.5465455724943176 1.3360606208594683 0.1815294598901276 1.0 0.2539796449204604 2 Q96TA2 1 +FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156] 0.6955812601801303 1.3189131352841488 0.1871981543028973 1.0 0.2599821200406954 4 O95831,P00390 2 +Cobalamin-binding domain superfamily [IPR036724] 0.5426532598118623 1.315821445972351 0.1882339793907124 1.0 0.2606529259404431 2 Q99707 1 +Ribosomal protein L14 superfamily [IPR036853] 0.5410314628608448 1.3073878170664417 0.1910810328396779 1.0 0.2622844453680004 2 Q6P1L8 1 +FERM superfamily, second domain [IPR035963] 0.5991333081055242 1.2810537180592652 0.2001747985555617 1.0 0.273572224692601 10 Q9Y2J2,Q9Y4F1 2 +Ubiquitin-conjugating enzyme/RWD-like [IPR016135] 0.5771392760322733 1.2727071842602653 0.2031219673322077 1.0 0.276797709818312 11 Q9Y3C8,Q9Y385,Q9C0C9,Q16763 4 +GYF-like domain superfamily [IPR035445] 0.60642439974043 1.2630922940546254 0.2065560130417911 1.0 0.2806661675769583 3 O75165,Q6Y7W6 2 +Myosin S1 fragment, N-terminal [IPR008989] 0.6048020765736557 1.2556393017872964 0.2092467752318674 1.0 0.2839132504225194 3 Q9UM54,P35579 2 +SH3-like domain superfamily [IPR036028] 0.4284215358480802 1.2191876902542649 0.2227729630061059 1.0 0.3018317587855716 24 Q9Y5K6,Q5JRA6,Q9Y371,Q9UQB8,Q96PC5 5 +Leucine-rich repeat domain superfamily [IPR032675] 0.4277967545414221 1.2145805569654502 0.2245261081584701 1.0 0.3037706169202832 24 Q8N1F8,Q96RT1,Q9Y2K7,O94813 4 +AH/BAR domain superfamily [IPR027267] 0.6275067905875727 1.1893825074075193 0.2342891811271756 1.0 0.3151757843908637 8 Q9UQB8 1 +YjeF N-terminal domain superfamily [IPR036652] 0.5183263055465379 1.1893729982685486 0.2342929213764533 1.0 0.3151757843908637 2 Q8NCW5 1 +Death-like domain superfamily [IPR011029] 0.6616869596760109 1.179660711325162 0.2381351859330536 1.0 0.3198881486251703 4 Q12955 1 +FERM/acyl-CoA-binding protein superfamily [IPR014352] 0.5373695910911293 1.1715068085320566 0.2413951227054607 1.0 0.3238059754071827 12 Q9H3P7,Q9Y2J2,Q9Y4F1 3 +EF-hand domain pair [IPR011992] 0.3538544157345878 1.1693202208918576 0.2422746391624799 1.0 0.3245241260372423 50 Q9BRK5,Q96AY3,Q14257,O95302,Q9NWM8,P80303,Q9H8M7,Q96D71,O43852,Q99653,Q7L5N7 11 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.6552448326671034 1.16845756149297 0.2426222480568018 1.0 0.3245287658405165 6 Q8WUJ1 1 +G protein alpha subunit, helical insertion [IPR011025] 0.6530347289840992 1.144199853232599 0.2525407639768149 1.0 0.3373171960766805 4 Q14344,P63096,P08754 3 +Initiation factor 2B-like, C-terminal [IPR042529] 0.5772225827384831 1.129152831682505 0.2588333676054133 1.0 0.3437744586646545 3 Q14232,Q9BV20 2 +Bromodomain-like superfamily [IPR036427] 0.4442232338123703 1.119499278796918 0.2629271983983452 1.0 0.347742423688134 18 Q15059,Q03164 2 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.4576347536812872 1.0916871689920793 0.2749706268475591 1.0 0.3621470685995087 16 P26640,Q13505,P78417,P28161 4 +Protein-tyrosine phosphatase-like [IPR029021] 0.5555651132241428 1.0675612748867551 0.2857184597137441 1.0 0.3731752181579787 10 Q99956,Q13614,Q9C0I1 3 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.6306394027913051 1.0527525067969743 0.2924544370136746 1.0 0.3814447221354012 4 P07437,Q9BUF5,Q9BUK6 3 +Phosphoribosyltransferase-like [IPR029057] 0.6218031907364373 1.0294679240137092 0.3032598451343093 1.0 0.3944469433953844 6 Q14558,O60256,Q06203 3 +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.429258347455587 1.0222864410481576 0.3066453487234173 1.0 0.398301052129728 18 P49721,P28074 2 +HECT, E3 ligase catalytic domain [IPR035983] 0.6052535680256145 1.0201221201354311 0.3076705471804275 1.0 0.398840310446058 7 Q96PU5,Q05086 2 +Bcl-2-like superfamily [IPR036834] 0.6221730844227207 1.0183561702856212 0.3085087234450285 1.0 0.398840310446058 4 Q07812 1 +TBP domain superfamily [IPR012295] 0.6187728954754498 1.016954118268054 0.3091752565599877 1.0 0.398840310446058 6 O95782,O94973,P63010 3 +Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028] 0.6187728954754498 1.016954118268054 0.3091752565599877 1.0 0.398840310446058 6 O95782,O94973,P63010 3 +Acyl-CoA N-acyltransferase [IPR016181] 0.5869539744539667 1.0082198168670529 0.3133489464398524 1.0 0.4036722083234711 8 Q86UY6 1 +PUA-like superfamily [IPR015947] 0.5866874081292828 1.007039066647722 0.3139160009272586 1.0 0.4038510080141949 8 O43252,Q96T88 2 +Armadillo-type fold [IPR016024] 0.2919114399314111 0.9964696859598128 0.3190219888583179 1.0 0.4088255511852447 135 Q7Z3U7,P52292,Q9UH62,O00410,Q99570,Q8IZL8,Q92538,O43592,Q9UBB6,P30154,P50851,O95782,Q8TF05,Q8TCG1,Q92797,Q9UI26,Q68CP9,O60763,Q96DX4,O75155,P55010,Q9P260,Q9NVT9,Q96P70,P42356,Q92973,O94973,Q9Y6E2,O95373,Q8N3U4,Q15021,P42345,Q9Y613,Q9NPQ8,Q96T76,P63010,Q5T4S7,Q96QK1 38 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.616110247939639 0.9937995443060852 0.3203204680384246 1.0 0.4092983758268759 4 P52888 1 +Zinc finger, FYVE/PHD-type [IPR011011] 0.3884627072005437 0.9883771478214148 0.3229679750433059 1.0 0.4113353592301133 27 Q96T88,Q03164,Q8WUB8,Q9Y2K7,Q9P1Y6 5 +PH-like domain superfamily [IPR011993] 0.3513262857218953 0.9878559019596737 0.3232232250153912 1.0 0.4113353592301133 43 Q6WCQ1,P31751,P50570,P50851,Q9Y4F1,Q9BZF1,Q86X55,Q9C0I1,Q9Y2J2,Q9BZF3,Q13614,Q9Y5P4,Q8NC96,Q9HCM4 14 +Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008] 0.6098294377385872 0.9801256141397828 0.3270241169481931 1.0 0.414494277260949 6 P26640,Q9NSE4 2 +Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041] 0.5922943474312413 0.9649208341883768 0.334584465269375 1.0 0.4235075848980142 7 Q10567,O95782,Q9Y678,P63010,O94973 5 +Oxysterol-binding protein superfamily [IPR037239] 0.6081874619605018 0.961817407557183 0.3361413322450439 1.0 0.4249078770872339 4 Q9BZF1,Q9BZF3 2 +L27 domain superfamily [IPR036892] 0.5370204342675386 0.9465873688669678 0.3438490828201019 1.0 0.4336272220660103 3 O14936 1 +AP-2 complex subunit mu, C-terminal superfamily [IPR036168] 0.6043492372606336 0.9463721314396604 0.3439588145338024 1.0 0.4336272220660103 4 Q9BXS5,Q9Y2T2,Q96CW1 3 +Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449] 0.5344869687565599 0.9352061427444448 0.3496820734547881 1.0 0.4396669270238202 3 A0AVT1 1 +Armadillo-like helical [IPR011989] 0.3145001539539303 0.9198037676222948 0.3576753141494329 1.0 0.447925393416886 95 P52292,Q9UH62,O00410,Q8IZL8,Q99570,O43592,P30154,Q9H1A4,P50851,O95782,Q8TF05,Q8TCG1,Q92797,Q9UI26,O60763,O75155,Q9P260,Q9NVT9,Q96P70,Q92973,O94973,O95373,Q15021,P42345,Q9Y613,Q9NPQ8,Q96T76,P63010 28 +Methylglyoxal synthase-like domain superfamily [IPR036914] 0.4644826467726104 0.912434323006204 0.3615401282280741 1.0 0.4521649083807346 2 P27708 1 +C2 domain superfamily [IPR035892] 0.398990319905165 0.8873028238016162 0.3749158856893935 1.0 0.4676530161443096 20 Q96PU5,Q96N67,Q96J02,O14976,Q86YS7 5 +MFS transporter superfamily [IPR036259] 0.4997382886171337 0.8821093112592573 0.3777176974040164 1.0 0.4705254803857165 11 Q6N075,Q16625,P41440,Q96ES6 4 +SWIB/MDM2 domain superfamily [IPR036885] 0.5181700194678847 0.8624053911533713 0.38846447489149 1.0 0.4776036503555086 3 Q92925,P41214 2 +Ubiquitin-activating enzyme [IPR035985] 0.5698894619370454 0.8133323907556363 0.4160275109026334 1.0 0.5042595665567909 5 Q13564,Q9UBE0,A0AVT1 3 +UBA-like superfamily [IPR009060] 0.4187229238114836 0.7916988482550447 0.4285362940544428 1.0 0.5177063198851409 15 Q9Y5A7,P45974,Q9NRR5,Q9H1I8,P43897 5 +NTF2-like domain superfamily [IPR032710] 0.562070544121231 0.7871282110204608 0.43120681641193 1.0 0.5199846903790921 6 Q13555 1 +Concanavalin A-like lectin/glucanase domain superfamily [IPR013320] 0.3836652163882997 0.7598247355808464 0.4473593552494634 1.0 0.5374011108283363 19 Q12907,P27797,P27824,Q96DX4,Q96S59,P50851,Q8WW59,P49257,Q92499,Q9UBL3,Q9BUJ2,O15344,P14373,O94813,Q14258 15 +Rho GTPase activation protein [IPR008936] 0.5533537833875822 0.7528049211925139 0.4515671491071926 1.0 0.5417656763461611 6 O15031 1 +Nucleic acid-binding, OB-fold [IPR012340] 0.329868609492968 0.7336783574655262 0.4631447919523646 1.0 0.5535431417123952 38 Q14562,P63241,P62487,Q9NQT5,P67809,P49736,P25205,P16989,Q13868,Q9NP64,P05198 11 +Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001] 0.5447888930884939 0.7155080212535172 0.4742951861828959 1.0 0.5654366126048935 5 O00178 1 +Winged helix-like DNA-binding domain superfamily [IPR036388] 0.3146203369286111 0.6962746451581112 0.486256848578789 1.0 0.5753787067408908 45 Q68CP9,O75381,Q8NB78,Q13616,P85037,P35269,P46063,P46783,Q96HY6,Q9BT78 10 +LEM/LEM-like domain superfamily [IPR011015] 0.5372226959687383 0.6902648619962459 0.4900276405769124 1.0 0.5766040272481879 6 P42167,Q8NC56,P50402,P42166 4 +B30.2/SPRY domain superfamily [IPR043136] 0.4435286236303473 0.6896909172954413 0.4903885788473454 1.0 0.5766040272481879 12 P14373 1 +Sec23/Sec24 helical domain superfamily [IPR036175] 0.5225620178970521 0.6315676300507531 0.5276694439817384 1.0 0.6160371887286348 5 O95487,Q15436 2 +Gelsolin-like domain superfamily [IPR036180] 0.5225620178970521 0.6315676300507531 0.5276694439817384 1.0 0.6160371887286348 5 O95487,Q15436 2 +Zinc finger, RING/FYVE/PHD-type [IPR013083] 0.2932136833169812 0.622576414172651 0.5335629144053136 1.0 0.6211726275113711 54 Q96T88,Q96DX4,Q03164,Q8WUB8,Q14527,Q9Y2K7,P14373,Q9P1Y6 8 +Zinc finger, PARP-type superfamily [IPR036957] 0.4038274408044088 0.6161865188857699 0.5377714248834748 1.0 0.6245301153511291 2 P49916 1 +Zinc finger, Sec23/Sec24-type superfamily [IPR036174] 0.5101514542689383 0.5841987707164464 0.5590865884923266 1.0 0.6476887628357052 4 O95487 1 +DNA polymerase family B, thumb domain [IPR042087] 0.4519792342634708 0.5809078257366226 0.5613025777650498 1.0 0.6478682139931969 3 Q07864,P28340 2 +DNA polymerase, palm domain superfamily [IPR023211] 0.4519792342634708 0.5809078257366226 0.5613025777650498 1.0 0.6478682139931969 3 Q07864,P28340 2 +ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034] 0.3908530651962347 0.5569192450659266 0.577582605059195 1.0 0.6609956269063361 2 P06576 1 +F-box-like domain superfamily [IPR036047] 0.3885825494648028 0.5467491228229916 0.5845511009002078 1.0 0.6673507120446682 2 Q8NEZ5 1 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.4756543469337012 0.5010802185008366 0.6163146680115013 1.0 0.6993799421598624 7 Q92804,P98175 2 +DHS-like NAD/FAD-binding domain superfamily [IPR029035] 0.4839343076683796 0.493720359508779 0.6215036846085529 1.0 0.7035749995028396 5 Q13423 1 +RuvBL1/2, DNA/RNA binding domain [IPR042487] 0.3713915017839762 0.4719445394875839 0.6369663755986139 1.0 0.7202149786444759 2 Q9Y230 1 +WW domain superfamily [IPR036020] 0.3882117429963859 0.3871640262607155 0.6986347802622284 1.0 0.7833681305437352 11 Q96PU5,Q96J02 2 +ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121] 0.3909798831927324 0.3561022183680284 0.721764015968078 1.0 0.7983448538572762 3 P25705,P06576 2 +WWE domain superfamily [IPR037197] 0.3903309539260166 0.353969108939098 0.7233620338882891 1.0 0.7987475385909328 3 Q7Z2W4,Q7Z6Z7 2 +Ankyrin repeat-containing domain superfamily [IPR036770] 0.3125414375894931 0.3439695745209167 0.7308691675354981 1.0 0.8056958706764678 17 P42771,Q9P0K7,Q12955,Q99549,Q6W2J9,Q96KQ7,Q9H9B1,Q99728,Q13418 9 +ADF-H/Gelsolin-like domain superfamily [IPR029006] 0.3760692207286658 0.3433125002318285 0.7313633778356907 1.0 0.8056958706764678 11 Q14019,P60981,Q15436,O95487,O95486 5 +ERO1-like superfamily [IPR037192] 0.3340901719104771 0.3257478095711413 0.7446151685725177 1.0 0.8174296902955579 2 Q86YB8 1 +Papain-like cysteine peptidase superfamily [IPR038765] 0.3048544743652529 0.3195699547338719 0.7492943535425196 1.0 0.8216099713844139 18 P45974,Q9H4L4,Q9NP73,Q86UV5,Q9P275,Q96K76 6 +SKP1/BTB/POZ domain superfamily [IPR011333] 0.407300984599719 0.2844213184022605 0.7760875235980562 1.0 0.8460699823733723 7 O43791,Q14145 2 +HAD superfamily [IPR023214] 0.2867738805612652 0.2554850996572849 0.7983484505985083 1.0 0.8648670974135604 19 Q9HD20,P98194,Q969T7,Q5TFE4 4 +HAD-like superfamily [IPR036412] 0.2867738805612652 0.2554850996572849 0.7983484505985083 1.0 0.8648670974135604 19 Q9HD20,P98194,Q969T7,Q5TFE4 4 +Ribosomal protein L23/L15e core domain superfamily [IPR012678] 0.3572355613238119 0.254076999538427 0.799436072140882 1.0 0.8648670974135604 3 P62750,P62847 2 +Aspartate decarboxylase-like domain superfamily [IPR009010] 0.3510707332900621 0.2375306554835163 0.8122451399495145 1.0 0.8756958012023971 3 Q8NB90,P46459 2 +HSP40/DnaJ peptide-binding [IPR008971] 0.3959295604506609 0.2371387824577213 0.8125491262482476 1.0 0.8756958012023971 4 P31689 1 +Ribosomal L18e/L15P superfamily [IPR036227] 0.345879299156387 0.2241301080998279 0.822656065483572 1.0 0.8825536629704305 3 P46776,Q07020 2 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.3770123078527487 0.2094186213880704 0.8341214572723334 1.0 0.8928223997818506 7 O43847 1 +ANL, N-terminal domain [IPR042099] 0.3437050950934713 0.180672177601419 0.8566248984188709 1.0 0.91173507811399 9 P33121,Q9P265 2 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.3205344827207926 0.165935123572965 0.8682080060343678 1.0 0.9184145701120758 3 P04439 1 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.3205344827207926 0.165935123572965 0.8682080060343678 1.0 0.9184145701120758 3 P04439 1 +DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921] 0.3545420986838622 0.1524282101568809 0.8788492085529049 1.0 0.9270187960462968 6 P40938,Q96S55,P40937 3 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.3250461920775186 0.1440101171430958 0.8854924805913649 1.0 0.9298657118014 9 Q9HD20,P98194,P35670 3 +P-type ATPase, A domain superfamily [IPR008250] 0.3250461920775186 0.1440101171430958 0.8854924805913649 1.0 0.9298657118014 9 Q9HD20,P98194,P35670 3 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.3250461920775186 0.1440101171430958 0.8854924805913649 1.0 0.9298657118014 9 Q9HD20,P98194,P35670 3 +NAD(P)-binding domain superfamily [IPR036291] 0.2204465694558773 0.1406167373821752 0.8881727251024782 1.0 0.9306076441907076 69 Q53GQ0,Q8N4Q0 2 +6-phosphogluconate dehydrogenase, domain 2 [IPR013328] 0.3391755923401539 0.1285827191199192 0.8976878409274107 1.0 0.9343483818924374 4 P31937,Q16836,Q49A26 3 +Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940] 0.3362847721581593 0.1243599030996179 0.9010303195316708 1.0 0.9367933752131926 4 P42345,P42356 2 +SMCs flexible hinge superfamily [IPR036277] 0.3266233766233926 0.1107652683281317 0.9118024876871388 1.0 0.9464514398143172 5 Q9UQE7,Q9NTJ3,O95347,A6NHR9 4 +Longin-like domain superfamily [IPR011012] 0.2830115099889499 0.1101038716982598 0.9123269976577036 1.0 0.9464514398143172 11 O75396,P51809 2 +Thiamin diphosphate-binding fold [IPR029061] 0.2811099895641712 0.0743120603865316 0.9407620807659228 1.0 0.9681097320685588 8 Q02218,A1L0T0 2 +Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864] 0.2111059001760812 0.0697513402835972 0.9443915776187056 1.0 0.9701103024993896 16 O95363,Q5JTZ9,Q9BW92 3 +S15/NS1, RNA-binding [IPR009068] 0.2835336148100115 0.0681477722639053 0.9456680019514752 1.0 0.9703644459632657 6 P56192,P82914,P23381,P41250,P07814 5 +SH2 domain superfamily [IPR036860] 0.2484010225484664 0.0647037268074651 0.94840989547971 1.0 0.9721201428667028 10 P62993,P07947,P07948,Q7KZ85,P41240,P46109 6 +ATPase, nucleotide binding domain [IPR043129] 0.1928646333714843 0.0596797585428545 0.9524106933376162 1.0 0.9747102943806056 17 Q9NVE7 1 +Anticodon-binding domain superfamily [IPR036621] 0.2661583385060251 0.0574954428478823 0.9541505361860838 1.0 0.9748255207188268 6 Q9BW92,Q9HCD5 2 +Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047] 0.2463438414039644 0.0530742360571801 0.9576727591602808 1.0 0.9756058743634544 8 P0DMV9,O95757,P54652,Q92598,P11142,Q9Y4L1,P34932 7 +Heat shock protein 70kD, C-terminal domain superfamily [IPR029048] 0.2463438414039644 0.0530742360571801 0.9576727591602808 1.0 0.9756058743634544 8 P0DMV9,O95757,P54652,Q92598,P11142,Q9Y4L1,P34932 7 +14-3-3 domain superfamily [IPR036815] 0.2559272491068595 0.0526408485587751 0.9580180696294368 1.0 0.9756058743634544 6 P27348,P61981,P62258,Q04917,P63104 5 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c44e8b6e34afedcfe2c18bef512a8b4ab3c85dbf --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioester hydrolase/BAAT, N-terminal [IPR042490]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "Apyrase superfamily [IPR036258]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Beta-trefoil domain superfamily [IPR036358]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DENN domain, C-terminal lobe [IPR043153]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA glycosylase [IPR011257]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IA, central region, subdomain 1 [IPR013824]", "DNA topoisomerase, type IA, central region, subdomain 2 [IPR013825]", "DNA topoisomerase, type IA, central region, subdomain 3 [IPR013826]", "DNA topoisomerase, type IA, core domain [IPR023405]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DUSP-like superfamily [IPR035927]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Deoxyhypusine synthase superfamily [IPR036982]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FCS-type zinc finger superfamily [IPR038603]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FTO, C-terminal domain superfamily [IPR038413]", "Fe-S cluster assembly domain superfamily [IPR034904]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like [IPR012347]", "Ferritin-like superfamily [IPR009078]", "Ferrodoxin-fold anticodon-binding domain superfamily [IPR036690]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarate reductase/succinate dehydrogenase, transmembrane subunit [IPR034804]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "H/ACA ribonucleoprotein complex, subunit Nop10 superfamily [IPR036756]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-hairpin-helix, base-excision DNA repair, C-terminal [IPR023170]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "I/LWEQ domain superfamily [IPR035964]", "IFT81, N-terminal domain superfamily [IPR043016]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrase-like, N-terminal [IPR017856]", "Integrin alpha, N-terminal [IPR028994]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex subunit 25, PTOV domain superfamily [IPR038196]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthioribose-1-phosphate isomerase, N-terminal [IPR027363]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "Moesin tail domain superfamily [IPR008954]", "Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily [IPR036522]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nuclear hormone receptor-like domain superfamily [IPR035500]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PCGF Ub-like fold discriminator superfamily [IPR038227]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PH-like domain superfamily [IPR011993]", "PIN-like domain superfamily [IPR029060]", "PINIT domain superfamily [IPR038654]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S1, PA clan, chymotrypsin-like fold [IPR043504]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Putative deacetylase LmbE-like domain superfamily [IPR024078]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RBP-J/Cbf11, DNA binding domain superfamily [IPR037095]", "RGS domain superfamily [IPR036305]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RNase P subunit Pop5/Rpp14/Rnp2-like domain superfamily [IPR038085]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RRF superfamily [IPR036191]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scaffold protein Nfu/NifU, N-terminal domain superfamily [IPR036498]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Set2 Rpb1 interacting domain superfamily [IPR038190]", "Seven-hairpin glycosidases [IPR036026]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Sodium/glucose symporter superfamily [IPR038377]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfatase-modifying factor enzyme superfamily [IPR042095]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Telomere repeat-binding factor, dimerisation domain superfamily [IPR036507]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonine synthase, N-terminal domain superfamily [IPR037158]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transcriptional regulator TACO1-like, domain 3 [IPR026564]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Triosephosphate isomerase superfamily [IPR035990]", "Tryptophan synthase beta subunit-like PLP-dependent enzyme [IPR036052]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UROD/MetE-like superfamily [IPR038071]", "UbiA prenyltransferase superfamily [IPR044878]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-associated protein 1, C-terminal [IPR042575]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "YEATS superfamily [IPR038704]", "YebC-like [IPR029072]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG13", "ALG5", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL10", "ARL2", "ARL3", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATRX", "ATXN10", "AURKA", "AURKB", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BCAS3", "BCAT2", "BCKDHA", "BCKDHB", "BCL2L13", "BCOR", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C1QBP", "C2CD5", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2A", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPV", "CEPT1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHORDC1", "CHP1", "CHRAC1", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT9", "CNP", "COA7", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCPS", "DCTN1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOHH", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDC4", "EDF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FIS1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GORASP2", "GOSR2", "GOT1", "GOT2", "GPATCH8", "GPD2", "GPI", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXB", "HGH1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMPDH2", "ING5", "INTS1", "INTS11", "INTS14", "INTS4", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL3", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LYAR", "LYN", "LYPLA1", "LZIC", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED16", "MED25", "MEPCE", "METTL16", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPG", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL4", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKIPSD", "NCL", "NCOA5", "NCOR1", "NDRG3", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAF1", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEK9", "NELFE", "NENF", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF3", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGL", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA1", "PRKAA2", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD6", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PUS1", "PWP1", "PWP2", "PYCR1", "PYCR2", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REPS1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "RP2", "RPA1", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RREB1", "RRM1", "RRM2", "RRP12", "RRP7A", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RTCB", "RTF1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SCAF11", "SCAF8", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC37A4", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMU1", "SMYD3", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPECC1L", "SPEN", "SPOP", "SPOUT1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STUB1", "STX10", "STX12", "STX3", "STX5", "STX6", "STX7", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFRC", "THEM6", "THNSL1", "THOC1", "THOC3", "THOC6", "THOP1", "THYN1", "TIAL1", "TIGAR", "TIMM10", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKT", "TLE3", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMED8", "TMEM14C", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBFD1", "UBIAD1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UFC1", "UFD1", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YKT6", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H13", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZCCHC17", "ZCCHC3", "ZEB2", "ZFR", "ZMYND8", "ZNF148", "ZNF280C", "ZNF281", "ZNF346", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF644", "ZPR1", "ZRANB2"], "leading_proteins": ["AARS2", "ACADM", "ACBD3", "ACSL1", "ADD3", "AFDN", "AIFM1", "AKT2", "ALDH7A1", "ALG13", "ANAPC1", "ANAPC5", "ANAPC7", "ANK3", "AP1B1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3M1", "ARID2", "ARMC1", "ARMCX3", "ASCC2", "ASH2L", "ASPH", "ATP13A1", "ATP2C1", "ATP5A1", "ATP5B", "ATP7B", "BAG6", "BAIAP2", "BARD1", "BAX", "BCOR", "BRD3", "BZW2", "C2CD5", "CAD", "CALR", "CALU", "CAMK2G", "CAND2", "CANX", "CARM1", "CASK", "CD2AP", "CDC23", "CDKN2A", "CHP1", "CIP2A", "CLUH", "COL4A3BP", "COPG1", "COPS4", "COTL1", "CRKL", "CSK", "CTR9", "CUL1", "CYB5D2", "DCTN1", "DDRGK1", "DDX1", "DHX8", "DIP2B", "DKC1", "DNAJA1", "DNAJC13", "DNAJC3", "DNAJC7", "DNM2", "DOCK7", "DSTN", "DUSP9", "EHMT1", "EHMT2", "EIF2B1", "EIF2D", "EIF2S1", "EIF3L", "EIF5", "EIF5A", "EMD", "EPB41L3", "EPB41L5", "EPRS", "ERBIN", "ERO1B", "EXOSC2", "EXOSC3", "FARP1", "FARS2", "FBXO22", "FHOD1", "FKBP10", "FKBP14", "FKBP5", "FKBP9", "FOXK1", "FOXRED1", "GABARAPL2", "GAK", "GARS", "GBF1", "GIGYF2", "GINS4", "GLYR1", "GNA13", "GNAI1", "GNAI3", "GRB2", "GSR", "GSTM2", "GSTO1", "GTF2F1", "GTF3C3", "GTPBP1", "HADH", "HIBADH", "HLA-A", "HLTF", "HMOX1", "HNRNPUL1", "HSD17B12", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPH1", "HUWE1", "HYOU1", "IARS2", "ILK", "ILVBL", "INTS8", "IPO11", "IPO5", "IPO7", "IPO9", "ITCH", "KDM1B", "KDM2A", "KEAP1", "KIAA1468", "KMT2A", "KPNA2", "L2HGDH", "LEMD2", "LIG3", "LMAN1", "LMAN2", "LPCAT2", "LRBA", "LYN", "MAN1A2", "MAPRE2", "MARS", "MCM2", "MCM3", "MFSD3", "MFSD5", "MIA2", "MIA3", "MID1", "MINDY3", "MMS19", "MOGS", "MON2", "MPHOSPH8", "MPI", "MPRIP", "MRI1", "MRPL14", "MRPS15", "MSTO1", "MTMR12", "MTMR2", "MTOR", "MTR", "MTX1", "MYH9", "MYO6", "NAA15", "NAA40", "NAE1", "NAP1L1", "NASP", "NAXE", "NCAPD2", "NCDN", "NCOA5", "NECAP1", "NEDD4L", "NNT", "NPEPPS", "NRDC", "NSF", "NT5C3B", "NT5DC1", "NUB1", "NUCB2", "OCLN", "OGDH", "OSBPL6", "OSBPL8", "P3H1", "P4HA1", "PABPC4", "PANK4", "PAPSS1", "PELP1", "PEX14", "PFN2", "PHF10", "PHRF1", "PI4KA", "PIK3R4", "PLXNB2", "PNPLA6", "POLD1", "POLE", "POLR1C", "POLR2G", "POLRMT", "PPAT", "PPP2R1B", "PPP4R1", "PRKAA1", "PRPSAP1", "PRPSAP2", "PSMB2", "PSMB5", "PSMD11", "RAI14", "RANBP9", "RBM10", "RCN2", "RECQL", "REPS1", "RFC3", "RFC5", "RIC8A", "RMDN1", "RPL18", "RPL23A", "RPL27A", "RPS10", "RPS24", "RPS3", "RSPRY1", "RUVBL2", "SAE1", "SDF4", "SEC22B", "SEC23A", "SEC24A", "SEC24B", "SEL1L", "SENP3", "SH3GLB1", "SLC19A1", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A33", "SLC25A40", "SLC25A42", "SLIT2", "SMARCD2", "SMC2", "SMC3", "SMC4", "SMCHD1", "SMYD3", "SPATA5", "SPOP", "SPRYD4", "SRP9", "SRSF7", "STAG2", "STK11IP", "SUGT1", "SUMF2", "SUPT6H", "SYMPK", "TAF15", "TARS2", "TBCB", "TECR", "THOP1", "TMPO", "TNPO1", "TRIM25", "TRIM27", "TSFM", "TSPAN3", "TTC19", "TTC26", "TTC37", "TTC4", "TUBB", "TUBB6", "UBA6", "UBE2J1", "UBE2O", "UBE2S", "UBE3A", "UBQLN4", "UBR4", "UBR5", "UBXN4", "UFC1", "UHRF1", "UNC119", "UNC119B", "USO1", "USP36", "USP47", "USP48", "USP5", "VAMP7", "VARS1", "VPS35", "WARS", "WRNIP1", "XPOT", "YBX1", "YBX3", "YES1", "YME1L1", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3HAV1", "ZCCHC17"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..26887daa400c4937312e6063b8c1bdfe56788237 --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b832f4f0df98c944b0a74585baa1136175b5ffa9c17e48148b286e30c949866d +size 69632 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1581c98699af3deacaa672a9637eaf884dd1123d --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 3.25 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..918fd9b8a5edaa02a45c2a93cb5d5496d2c8dc05 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c077cee76d4c06b3f327eacdd8108d734c6005d0 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.3250461920775186 0.1440101171430958 0.8854924805913649 0.9998280761902418 0.8854924805913649 9 Q9HD20,P98194,P35670 3 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9451c76ea4fd2949330f777bfb1b9ffd4c969e01 --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP7A", "ATP7B", "EIF5A", "FASN", "LDLR", "SLIT2"], "leading_proteins": ["ATP13A1", "ATP2C1", "ATP7B"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c7661eb0e02bf0b0ade51d1102ed55394e61b9f8 --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]", "1": "Tetratricopeptide repeat [IPR019734]", "2": "Ankyrin repeat [IPR002110]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..53efaf59061ce6aed72b7f1f826b985bdb3c7b24 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8e8121e76dd7deeb074d79b66f760c3b4bbd4a1dcd705af8ec834a5175ad9b43 +size 139333 diff --git a/interpro_repeat/basic/plot_1.png b/interpro_repeat/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..0336099e5d4ceda2d9590b9a9d06fb4d670fc11c --- /dev/null +++ b/interpro_repeat/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:767cbb57a7d32bc33ca349ac53bcfe698f42ec67b44ea2f67ad73db6a1f5dd3d +size 141045 diff --git a/interpro_repeat/basic/plot_2.png b/interpro_repeat/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..252bc0da36632bfc73c6ac71ea9e25a9c6d324c6 --- /dev/null +++ b/interpro_repeat/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f08724c65234917030be9eddbefa1e78c928c4d3ce700d1528a0a9b332c68e73 +size 145688 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..2d391d24ecba4a377f2908a0ba5cfec9b8358e9e --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e7fbdbb8f5e7c5f1f0b343a243f6d1408fea7c9f8e44a85079d8a23dfcbe3fb2 +size 85405 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..63aa93e87d045ebfa92da9350fe634d542ae7bb5 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 75, + "title": "Average number of proteins per term", + "value": 5.253333333333333 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b42d9877fea557e7dfa61cca767d21da0458e33c --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..94bf4a2bc11f5e1c0ac7440c1d785a97de5bd7f0 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,13 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.522057915754968 1.911228033889158 0.0559752827412824 0.986703038429479 0.0954124137635497 24 O43772,Q9BQT8,Q70HW3,O43808,Q9BSK2,Q8TBP6,Q86VD7 7 +HEAT, type 2 [IPR021133] 0.6425396583264265 1.8672222611602327 0.0618705561363444 0.9916879621636296 0.1008759067440397 13 Q8TF05,Q9P260,P30154 3 +HEAT repeat [IPR000357] 0.7681648126044041 1.6275652002721908 0.1036171130620742 0.9997264625751148 0.1554256695931113 5 Q8TF05,P30154 2 +Tetratricopeptide repeat [IPR019734] 0.4178077242112198 1.566214651406124 0.1172983738194459 0.999913693302079 0.1670032996177764 41 Q6PD62,Q6DKK2,Q13451,Q9UJX2,Q9UJX3,O95801,Q12797,A0AVF1,P53041,Q13217,Q9Y5Q9,Q9UJX4,P13674,Q99615,Q9BXJ9,P49321,Q9Y2Z0,Q6PGP7 18 +Leucine-rich repeat [IPR001611] 0.3684471728822065 0.6667838875188196 0.5049101860853882 1.0 0.6107784509097438 19 Q8N1F8,Q96RT1,O94813 3 +Leucine rich repeat 4 [IPR025875] 0.3981181051265354 0.3799746772806031 0.7039642124931924 1.0 0.8380526339204671 3 Q9UFC0,Q13045 2 +Leucine-rich repeat, typical subtype [IPR003591] 0.3601694202929061 0.3324164485557996 0.7395748199034071 1.0 0.8533555614270082 12 Q96RT1,O94813 2 +Calponin repeat [IPR000557] 0.3773523685918178 0.312663643042992 0.7545362202385693 1.0 0.8574275229983741 3 Q99439,Q15417 2 +Ankyrin repeat [IPR002110] 0.3082688576577887 0.2653895125185203 0.7907094143984799 1.0 0.8721059717630293 15 Q9P0K7,Q12955,Q99549,Q6W2J9,Q96KQ7,Q9H9B1,Q99728,Q13418 8 +Armadillo [IPR000225] 0.2688186499676806 0.1187441990994322 0.9054780184303576 1.0 0.9386126089504748 13 P52292,P63010,Q9UH62,Q9NVT9 4 +Filamin/ABP280 repeat [IPR001298] 0.3248651363018797 0.1085203493645216 0.9135829393784622 1.0 0.9386126089504748 5 Q14315 1 +Filamin/ABP280 repeat-like [IPR017868] 0.3248651363018797 0.1085203493645216 0.9135829393784622 1.0 0.9386126089504748 5 Q14315 1 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..be638f71af8c627874359fb663de0fd53d9352ca --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "FG-GAP repeat [IPR013517]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Fis1, C-terminal tetratricopeptide repeat [IPR028061]", "Fis1, N-terminal tetratricopeptide repeat [IPR028058]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hs1/Cortactin [IPR003134]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "Integrin alpha beta-propellor [IPR013519]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PQ-loop repeat [IPR006603]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "ACTN1", "ACTN4", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC1", "ARMC6", "ARMCX3", "ARPC1A", "ASPH", "BARD1", "BCOR", "BIRC6", "BOP1", "BUB3", "CAST", "CDC16", "CDC23", "CDC27", "CDC40", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "COA7", "COLEC12", "COPA", "COPB2", "CORO1C", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "EDC4", "EED", "EHMT1", "EHMT2", "EIF3I", "ELP2", "EMC1", "EMC2", "EPPK1", "ERBIN", "FIS1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "GCN1", "GEMIN5", "GLG1", "GLS", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HUWE1", "IGF2R", "ILK", "INTS4", "IPO4", "IPO5", "ITGAV", "JUP", "KAT7", "KDELC1", "KDELC2", "KDM2A", "KEAP1", "KIAA1468", "KIDINS220", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "L3MBTL3", "LARP1", "LASP1", "LDLR", "LRBA", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "MACF1", "MAP4", "MAU2", "MED16", "MKI67", "MPDU1", "MPHOSPH8", "MRPS27", "MTCH1", "MTCH2", "MTPN", "NAA15", "NASP", "NEK9", "NHLRC2", "NIPBL", "NISCH", "NLE1", "NOL10", "NOP2", "NOP9", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "P4HA1", "PAFAH1B1", "PAK1IP1", "PDCD11", "PHIP", "PIK3R4", "PLEC", "PLRG1", "PLXNB2", "POLR2A", "PPID", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PREB", "PRKCSH", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM3", "PWP1", "PWP2", "RACK1", "RAE1", "RAI14", "RANBP2", "RANGAP1", "RBBP5", "RBBP7", "RCC1", "RCC2", "RNH1", "RPAP3", "RRP9", "SART3", "SCML2", "SCRIB", "SEC31A", "SEH1L", "SEL1L", "SGTA", "SHCBP1", "SIN3A", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STK11IP", "STRAP", "STRN", "STRN4", "STUB1", "SUGT1", "SYNE2", "TAGLN2", "TBL1XR1", "TBL2", "TBL3", "TEX10", "THOC3", "THOC6", "TLE3", "TMTC3", "TOMM34", "TOMM70", "TPBG", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "XAB2", "XPO1"], "leading_proteins": ["ANAPC5", "ANAPC7", "ANK3", "AP2B1", "ARMC1", "ARMCX3", "ASPH", "BARD1", "BCOR", "CDC23", "CNN2", "CNN3", "CTR9", 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0000000000000000000000000000000000000000..c5dcb7afd4c44b482b7cd13282f60c28b3f23a28 --- /dev/null +++ b/msigdb_gobp/df_merge.tsv @@ -0,0 +1,21 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Protein polyubiquitination 11 45 2.50112625609308 0.0123799034818392 12.611650485436892 49.88592233009709 0.2698122167105246 0.6118505816632617 6.467218320876326 7.957965776185411 0.9830885011877004 0.3433598945202875 1.0 1.0 0.1280872541532376 0.1144375788093372 0.2689662880213787 +Cellular modified amino acid biosynthetic process 1 20 2.40302035615814 0.0162602822648123 6.783980582524272 19.96359223300971 -0.8059615834535448 0.3681050521290121 3.5368292090503743 2.008751413563429 1.051244812607991 0.3007299933118866 0.0005825810467265 0.0115082778780227 0.0428134756181982 0.2012424218570439 0.2308247548684397 +Demethylation 3 14 2.380159281398737 0.0173051561153056 3.79126213592233 16.33252427184466 0.3770974740725703 0.5862274319476604 2.645773577706271 2.169651763229003 0.7821438136430354 0.3008344506592516 0.0536916217909721 0.2183067054048652 0.0876106046642714 0.0354428499477605 0.2384745593347044 +Response to hydrogen peroxide 3 26 2.3199360459283813 0.0203443372663025 5.070388349514563 26.026699029126213 0.2720488226072516 0.5579156584117564 3.330849747941118 3.673146554174725 0.8832950272986575 0.3050219051530477 0.0899989539276798 0.343540942585206 0.0100671525325501 0.1632106984779044 0.6219417637890827 +Amino acid betaine metabolic process 2 7 2.284802896335786 0.0223243877633922 2.424757281553398 6.652912621359223 -0.5303235840950383 0.3373366152950036 1.1089524004774276 1.0605074175394698 1.1570448153598685 0.2485913468276022 4.739609912176877e-05 0.0009934566258862 0.0039921150854813 0.0015206572897169 0.0108028806477149 +Positive regulation of protein kinase activity 15 40 2.250132168717951 0.0244405565793117 12.74514563106796 53.13834951456311 -0.3110644454045805 0.6570774469735688 6.342230223043985 7.797048557495115 0.6800761942316077 0.2828651620972058 1.0 0.6739366433451586 0.8966728068670702 0.9234343624946733 0.9381324804112988 +Regulation of dna methylation 1 10 2.205956026820814 0.0273870787517156 1.9927184466019416 8.83252427184466 0.7131887814592797 0.4532119966636778 1.6480189308548123 1.5386952097280358 0.8551167704417201 0.3087271346477002 0.0001426524209436 0.0029386578360865 0.0115435449528709 0.0635022977163126 0.0475092322455766 +Organic cation transport 4 7 2.2020118064716887 0.0276644744995229 2.191747572815534 5.524271844660194 1.626219676916526 0.1372808582950073 1.481153399412497 1.209546654977186 0.871004228766265 0.1892257790071234 0.0224349556832642 0.0044823878286489 0.0010401540441919 0.0014975917181939 0.0029149932554685 +Dna methylation or demethylation 1 24 2.1726805209002307 0.029804370847362 5.436893203883495 23.0873786407767 0.1823966461973749 0.6056359808060879 4.05524927205437 3.2727376269841373 0.8218396137348795 0.2995399810457916 0.0019316383055609 0.0356328568827733 0.1215022402141297 0.4495102823409708 0.3605963383000652 +Small gtpase mediated signal transduction 26 77 2.1640613691749806 0.0304596398087282 16.356796116504853 91.21601941747574 0.1727656671625839 0.7482101099058196 8.137553926696144 13.195300563855934 0.631620482148095 0.3023140298974312 0.3312353411206016 0.2570067626682825 0.4776342600774479 0.4041170020560941 0.6245901302748478 +Dna methylation 1 20 2.114803334161786 0.0344467125961736 4.283980582524272 18.48058252427185 0.3368664558597276 0.5549461558551047 3.1251307824457446 3.053266856273282 0.885226763878063 0.3084732602561963 0.0010214476465593 0.0196403757049561 0.0705821305211966 0.3010844649684869 0.1766982307470584 +Protein localization to endoplasmic reticulum 14 36 2.105842870556436 0.0352180035301512 9.50242718446602 34.50485436893204 0.9935384348474128 0.428255638055916 4.399083524593319 2.6617527855555916 1.1934894982037212 0.3717243536861919 1.0 1.0 0.4274740864709498 0.0124412460735711 0.0016517763494143 +Plasma membrane organization 4 21 2.090472620283973 0.0365753654012421 7.099514563106796 28.24514563106796 0.6737258386983643 0.4958528160030953 3.5234718862626195 4.368421626063976 0.8695791931528731 0.3271220115282837 1.0 0.0576595399457578 0.185657500723835 0.0477957943736139 0.2045133113677179 +Dna modification 2 31 2.085684952335565 0.0370071703855157 7.449029126213592 29.95631067961165 0.0525974592283249 0.623813202387164 4.976627316341219 4.039613792529995 0.8319095595259771 0.3052628102732242 0.0030387764801614 0.0539251864958397 0.0400324838097305 0.2971320950388168 0.3344119037618643 +Response to l glutamate 1 5 2.039699130187404 0.0413803016160905 1.029126213592233 4.37378640776699 1.2967513270419406 0.258405010407401 0.7465949978845596 0.5879801140961596 0.7687098467942305 0.2572187080379352 1.0 0.0424464003246627 0.0032139762811053 0.0190953097419897 0.0684923167064351 +Regulation of dendritic spine development 1 14 2.029379914372041 0.0424196093101703 3.6140776699029127 14.00485436893204 0.2181416094069509 0.5920057818841689 2.9876925333071065 1.844692130536013 0.7837652286753845 0.2867103096614373 1.0 0.1952735388158895 0.0705821305211966 0.3010844649684869 0.6539689415835621 +Succinyl coa metabolic process 2 5 2.019946577636016 0.0433889291840361 2.9223300970873787 4.080097087378641 -0.9061375967031344 0.3825591328328238 1.083318529642589 0.2887737554491004 0.8074023673863194 0.288678092673427 1.0 1.0 0.0018987369599165 0.0115035556388008 0.00351763180786 +Carnitine metabolic process 1 5 2.019456525277393 0.0434397915734656 1.8907766990291264 5.584951456310679 0.0609785321453339 0.4105567470620494 1.1105025446134678 0.9976023428885448 1.1033989692507622 0.2543534563670523 0.0086012577526047 0.0378187125466048 0.075113296023457 0.0150927838189798 0.0550149107858915 +Regulation of dendritic spine morphogenesis 1 12 1.9939867492510783 0.0461535026258606 3.703883495145631 12.548543689320388 0.2142559788076415 0.5641772072204894 3.211732809078622 1.316465116678391 0.828916671050933 0.2901049414664307 1.0 0.1635258499471353 0.0498890213657128 0.2282899009392132 0.5468190193174864 +Positive regulation of protein phosphorylation 26 82 1.986945175810792 0.0469284726243068 23.52912621359223 102.41747572815534 -0.1488034303965219 0.6803237542322728 10.19954435559452 13.30415240810006 0.7080058848245556 0.295006179138482 1.0 0.2858811680905303 0.5236314238684646 0.4768970927926154 0.7174415800437668 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c9a27b6ef9ab75ce2f533eba47e7396bb63f6f72 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 6406, + "title": "Average number of proteins per term", + "value": 18.13877614736185 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3ceb3c5b9076277935955ed9f58fe5cd9efa4abf --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..96a5bf7fa724ed6e781ec761fdc65ccb3bd177b3 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1896 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Regulation of caveolin mediated endocytosis 0.9688614985403812 3.3544678131475525 0.0007951780345378 0.9938784310222178 0.013656596485924 2 Q13432 1 +Negative regulation of response to food 0.953616607200777 3.2890297396938686 0.0010053340033313 0.998409026295501 0.0157967575642441 2 Q9UMX5 1 +Regulation of appetite 0.953616607200777 3.2890297396938686 0.0010053340033313 0.998409026295501 0.0157967575642441 2 Q9UMX5 1 +Regulation of response to food 0.953616607200777 3.2890297396938686 0.0010053340033313 0.998409026295501 0.0157967575642441 2 Q9UMX5 1 +Protein localization to axon 0.9429127473240352 3.2427689776621227 0.0011837415314124 0.9994932739216932 0.0170542310292578 2 Q12955 1 +Histone h3 k36 demethylation 0.942264028543624 3.239956871410261 0.0011954778010143 0.999530016075635 0.0170542310292578 2 Q9Y2K7 1 +Paranodal junction assembly 0.9279922153746344 3.177844909108913 0.001483740949896 0.9999260338403408 0.0186735648821882 2 Q9Y2J2 1 +Olfactory lobe development 0.9085306519623718 3.092381114652426 0.0019855774856969 0.9999970457152952 0.0227135881667404 2 O94813 1 +Tangential migration from the subventricular zone to the olfactory bulb 0.9085306519623718 3.092381114652426 0.0019855774856969 0.9999970457152952 0.0227135881667404 2 O94813 1 +Roundabout signaling pathway 0.897826792085628 3.0449942085276382 0.0023268479053604 0.9999996696642848 0.025093918656126 2 O94813 1 +Cell motility involved in cerebral cortex radial glia guided migration 0.8936101200129734 3.0262514696038325 0.0024760628092064 0.9999998732853416 0.0265689419694746 2 O94901 1 +Negative regulation of mononuclear cell migration 0.8741485566007093 2.939190491104828 0.0032907075543304 0.9999999993241389 0.0325817733649569 2 O94813 1 +Ornithine transport 0.8718780408692809 2.928973410942134 0.0034008351240693 0.999999999667 0.0325817733649569 2 P30825 1 +Gdp mannose metabolic process 0.8689588063574384 2.915818631953914 0.0035475665901367 0.9999999998703416 0.0326988655775772 2 P34949 1 +Response to cisplatin 0.8637690561141677 2.892380740143854 0.0038233430459633 0.9999999999779844 0.0337801800262289 2 P09601 1 +Positive regulation of lipid catabolic process 0.8634446967239643 2.890913673458827 0.0038412361923674 0.9999999999803776 0.0337801800262289 2 P50416 1 +Positive regulation of fatty acid oxidation 0.8634446967239643 2.890913673458827 0.0038412361923674 0.9999999999803776 0.0337801800262289 2 P50416 1 +Regulation of long chain fatty acid import across plasma membrane 0.8634446967239642 2.890913673458827 0.0038412361923674 0.9999999999803776 0.0337801800262289 2 P33121 1 +Positive regulation of fatty acid beta oxidation 0.8634446967239643 2.890913673458827 0.0038412361923674 0.9999999999803776 0.0337801800262289 2 P50416 1 +Response to hydroperoxide 0.8624716185533554 2.886510919048474 0.0038953923044682 0.9999999999861484 0.0339047324761188 2 P10620 1 +3 phosphoadenosine 5 phosphosulfate biosynthetic process 0.852092118066814 2.839402720234567 0.0045198074064627 0.9999999999997504 0.038097218744474 2 O43252 1 +Heart valve morphogenesis 0.8430100551410902 2.797963771308344 0.0051425880465494 0.9999999999999954 0.0422670066941645 2 O94813 1 +Positive regulation of ryanodine sensitive calcium release channel activity 0.8426856957508866 2.7964800068426032 0.005166260730804 0.999999999999996 0.0422670066941645 2 P78417 1 +Regulation of skeletal muscle contraction 0.8426856957508866 2.7964800068426032 0.005166260730804 0.999999999999996 0.0422670066941645 2 P78417 1 +Regulation of skeletal muscle contraction by calcium ion signaling 0.8426856957508866 2.7964800068426032 0.005166260730804 0.999999999999996 0.0422670066941645 2 P78417 1 +Choline metabolic process 0.953026409289732 2.78003285062069 0.0054353399715441 0.9999999999999992 0.0434699900787244 3 P49419 1 +Positive regulation of systemic arterial blood pressure 0.8374959455076185 2.772704003679878 0.0055592661823444 0.9999999999999996 0.0440750732228944 2 P61586 1 +Negative regulation of protein import into nucleus 0.8323061952643495 2.7488605179803143 0.0059802828714432 1.0 0.046833364394212 2 Q99653 1 +Positive regulation of protein glycosylation 0.8323061952643495 2.7488605179803143 0.0059802828714432 1.0 0.046833364394212 2 Q99653 1 +Negative regulation of protein autophosphorylation 0.8323061952643495 2.7488605179803143 0.0059802828714432 1.0 0.046833364394212 2 Q99653 1 +Endoplasmic reticulum mannose trimming 0.8235484917288304 2.708471043336386 0.0067594010323297 1.0 0.0505849567910097 2 Q9NYU2 1 +Regulation of membrane tubulation 0.8219266947778062 2.700970283580726 0.0069137515513759 1.0 0.051145789847201 2 Q9Y371 1 +Caveolin mediated endocytosis 0.930680845247065 2.688871267271205 0.0071694061434322 1.0 0.0523685470408514 3 Q13432 1 +Folic acid containing compound catabolic process 0.8160882257541351 2.6739124698944017 0.0074972016768191 1.0 0.0538420111454071 2 Q8IYS1 1 +Amino sugar catabolic process 0.8128446318520894 2.658843036339025 0.0078409483589245 1.0 0.0556863804736958 2 P26572 1 +Glucosamine containing compound metabolic process 0.8128446318520844 2.658843036339006 0.007840948358925 1.0 0.0556863804736958 2 O60502 1 +N acetylglucosamine metabolic process 0.8128446318520844 2.658843036339006 0.007840948358925 1.0 0.0556863804736958 2 O60502 1 +Phototransduction 0.9223969887492413 2.654827134557651 0.0079349059561657 1.0 0.0561048648512117 3 Q13432 1 +Detection of light stimulus 0.9223969887492413 2.654827134557651 0.0079349059561657 1.0 0.0561048648512117 3 Q13432 1 +Cellular response to purine containing compound 0.8050600064871858 2.622567378486079 0.0087270009770685 1.0 0.060177791452208 2 P28161 1 +Cellular response to caffeine 0.8050600064871858 2.622567378486079 0.0087270009770685 1.0 0.060177791452208 2 P28161 1 +Negative regulation of muscle organ development 0.9102555225103932 2.60468457307843 0.0091958875591302 1.0 0.0626008485004161 3 Q9NQ29 1 +Negative regulation of muscle tissue development 0.9102555225103932 2.60468457307843 0.0091958875591302 1.0 0.0626008485004161 3 Q9NQ29 1 +Detection of external biotic stimulus 0.7992215374635098 2.5952594079215956 0.0094519551218315 1.0 0.0631378774874375 2 P04439 1 +Histone h3 k4 demethylation 0.9046557986590466 2.581460146334267 0.0098383350138275 1.0 0.064310585814877 3 Q8NB78 1 +Negative regulation of potassium ion transmembrane transport 0.894416832320615 2.538833888732966 0.011122261749215 1.0 0.0700078544020992 3 Q96PU5 1 +Negative regulation of potassium ion transport 0.894416832320615 2.538833888732966 0.011122261749215 1.0 0.0700078544020992 3 Q96PU5 1 +Regulation of neurotrophin trk receptor signaling pathway 0.7833279273434857 2.5204800463505426 0.0117194882658997 1.0 0.0722862305385634 2 Q96F07 1 +Positive regulation of neurotrophin trk receptor signaling pathway 0.7833279273434857 2.5204800463505426 0.0117194882658997 1.0 0.0722862305385634 2 Q96F07 1 +Protein polyubiquitination 0.5032221458994806 2.50112625609308 0.0123799034818392 1.0 0.0750130411212501 45 Q96PU5,Q9UJX3,Q9H1A4,P55786,O43791,Q96J02,Q16763,P52888,P14373,Q9C0C9,Q05086 11 +Positive regulation of histone h3 k9 acetylation 0.7791112552708297 2.5005321266773355 0.0124006885025607 1.0 0.0750130411212501 2 Q12824 1 +Thyroid hormone mediated signaling pathway 0.7784625364904236 2.4974591726845774 0.0125086868227346 1.0 0.075240044869895 2 P42785 1 +Glyoxylate metabolic process 0.8840090860159459 2.495291400641618 0.0125853728943787 1.0 0.0754180530976524 3 P48735 1 +Negative regulation of tumor necrosis factor superfamily cytokine production 0.8837807389030046 2.4943336575619233 0.0126193859223655 1.0 0.075503643842055 3 P14373 1 +Neuron projection extension involved in neuron projection guidance 0.7761920207589909 2.486695340565375 0.0128935762877673 1.0 0.076697144590987 2 O94813 1 +Modulation of excitatory postsynaptic potential 0.8786503930010316 2.4727883863434283 0.0134063499705585 1.0 0.0793725304171886 3 Q9UQB8 1 +Protein localization to microtubule end 0.7658125202724512 2.4373209608444006 0.0147965394788902 1.0 0.0854703624001542 2 Q15555 1 +Error prone translesion synthesis 0.765488160882246 2.435773561157702 0.0148599835686602 1.0 0.08560526505471 2 P49005 1 +Angiogenesis involved in wound healing 0.7625689263704098 2.4218348285857676 0.0154423676466364 1.0 0.0882404589877688 2 P42785 1 +Nucleotide sugar biosynthetic process 0.8641564856593115 2.4116370966046183 0.0158810799641928 1.0 0.0896336548463607 3 P34949 1 +Mesonephric tubule morphogenesis 0.8637308427658728 2.409834948348022 0.0159597387964613 1.0 0.0899983157835666 3 Q13418 1 +Cellular modified amino acid biosynthetic process 0.623227438030998 2.40302035615814 0.0162602822648123 1.0 0.0906630207086613 20 P11310 1 +Negative regulation of immunoglobulin production 0.756081738566333 2.3907816873298264 0.0168125466011301 1.0 0.0922769895890373 2 Q96FV9 1 +Demethylation 0.7077145227183954 2.380159281398737 0.0173051561153056 1.0 0.0931570000627296 14 Q9Y2K7,Q8NB78,Q9H6W3 3 +Positive regulation of isotype switching to iga isotypes 0.7525137852740793 2.3736565250030472 0.0176129260924118 1.0 0.0940078519069259 2 O96028 1 +Terminal button organization 0.7518650664936746 2.370539359286536 0.0177621526453624 1.0 0.0945052739586308 2 O95295 1 +Manganese ion transmembrane transport 0.8533419857235405 2.3657374797102366 0.0179941987285243 1.0 0.0952993797035328 3 Q9HC07,Q9HD20 2 +Manganese ion transport 0.8533419857235405 2.3657374797102366 0.0179941987285243 1.0 0.0952993797035328 3 Q9HC07,Q9HD20 2 +Cellular response to leucine 0.7502432695426482 2.3627417359519636 0.0181403063838159 1.0 0.0957222427468902 2 P42345 1 +Regulation of mitochondrial atp synthesis coupled electron transport 0.8516685785073875 2.3586143492857636 0.0183433074436516 1.0 0.0964755562266276 3 P14635 1 +Peripheral nervous system axon regeneration 0.7486214725916214 2.3549373878424764 0.0185258269334998 1.0 0.0972757765049178 2 P07196 1 +Regulation of mast cell activation involved in immune response 0.8496999872191164 2.350227611550834 0.0187619342231704 1.0 0.0978737383010013 3 P09601 1 +Acid secretion 0.746026597469994 2.342436451637842 0.0191582962752594 1.0 0.0994554667255364 2 P80404 1 +Regulation of fatty acid beta oxidation 0.8472417838987851 2.3397442107165194 0.0192969510506113 1.0 0.1000131621603692 3 P50416 1 +N terminal protein amino acid acetylation 0.8450442907740023 2.3303625211837584 0.0197869988869761 1.0 0.1018520529638449 3 Q86UY6 1 +Regulation of retrograde transport endosome to golgi 0.7427830035679552 2.3267861072076017 0.0199766521987529 1.0 0.1025404118471247 2 P53367 1 +Amino acid betaine biosynthetic process 0.9471497404685696 2.325135635835184 0.0200647086734302 1.0 0.102909946967169 4 P11310 1 +Transcription initiation from rna polymerase iii promoter 0.8431450202652827 2.322246327184074 0.0202196757709507 1.0 0.1029205060018553 3 Q9Y5Q8 1 +Response to hydrogen peroxide 0.5682871918510426 2.3199360459283813 0.0203443372663025 1.0 0.1030243672157583 26 Q99720,P09601,Q05086 3 +Regulation of vascular associated smooth muscle contraction 0.7362958157638566 2.295404971507297 0.0217099267120117 1.0 0.1089066487996467 2 P61586 1 +Response to corticosterone 0.7362958157638556 2.2954049715072933 0.0217099267120119 1.0 0.1089066487996467 2 P07196 1 +Bile acid and bile salt transport 0.7359714563736639 2.2938331034379855 0.0218000871625654 1.0 0.1091879267892057 2 Q13131 1 +Magnesium ion homeostasis 0.8356636463557603 2.2902066987278364 0.0220093372993326 1.0 0.1098922951983825 3 Q12955 1 +Amino acid betaine metabolic process 0.9021836266131658 2.284802896335786 0.0223243877633922 1.0 0.1110326304443253 7 P11310,P49419 2 +Sugar mediated signaling pathway 0.8288389179043469 2.260883042701476 0.0237665004519027 1.0 0.115866211487739 3 Q12824 1 +Embryonic hemopoiesis 0.9276401809768292 2.250135918268291 0.0244403186322443 1.0 0.1182453188242795 4 Q03164 1 +Positive regulation of protein kinase activity 0.4949655322317811 2.250132168717951 0.0244405565793117 1.0 0.1182453188242795 40 Q8NDZ4,P42345,P33121,Q9HAW4,P23396,P14635,Q13432,Q9BZF1,Q9NQS7,P54619,Q96M27,Q96A49,Q9ULW0,P61586,Q00535 15 +Positive regulation of dopamine receptor signaling pathway 0.7262406746675328 2.246552943284997 0.0246686123902437 1.0 0.1185499857253574 2 Q96QK1 1 +Regulation of dopamine receptor signaling pathway 0.7262406746675328 2.246552943284997 0.0246686123902437 1.0 0.1185499857253574 2 Q96QK1 1 +Intracellular distribution of mitochondria 0.8253241592090848 2.2457455854057673 0.0247203085002494 1.0 0.1187093675056955 3 O75153 1 +Protein demannosylation 0.8238157040882379 2.239241511351969 0.0251402062078729 1.0 0.1201851947519657 3 O60476,Q9NYU2 2 +Cellular response to insulin like growth factor stimulus 0.8197670890727498 2.221762934917189 0.0262993308366175 1.0 0.1243659902834202 3 Q9BSK2 1 +Regulation of protein glycosylation 0.8166414405440897 2.208247107125279 0.0272270522296247 1.0 0.1275907070833768 3 Q99653 1 +Regulation of dna methylation 0.7902025829566511 2.205956026820814 0.0273870787517156 1.0 0.1281531238009426 10 Q8NB78 1 +Azole transmembrane transport 0.7178073305222076 2.2053833058645083 0.0274272085024382 1.0 0.1282472245741749 2 P30825 1 +Organic cation transport 0.8819703972112439 2.2020118064716887 0.0276644744995229 1.0 0.12888627174105 7 Q8WWI5,Q86VD7,Q70HW3,O43772 4 +Cellular response to ph 0.8144062297209603 2.198570031143975 0.0279085098711573 1.0 0.1297620996306366 3 Q99653,Q9UHD1 2 +Cellular response to acidic ph 0.8144062297209603 2.198570031143975 0.0279085098711573 1.0 0.1297620996306366 3 Q99653,Q9UHD1 2 +Nucleotide binding domain leucine rich repeat containing receptor signaling pathway 0.8128797842787607 2.1919558982548866 0.0283826912253002 1.0 0.1314388374839624 3 Q96RT1 1 +Branched chain amino acid biosynthetic process 0.7132662990593452 2.183141074830327 0.0290254225403974 1.0 0.1335810013284158 2 A1L0T0 1 +Regulation of apoptotic dna fragmentation 0.810468153755517 2.181497035252823 0.0291466735057337 1.0 0.1337489903135604 3 O95831 1 +Regulation of dna catabolic process 0.810468153755517 2.181497035252823 0.0291466735057337 1.0 0.1337489903135604 3 O95831 1 +Coronary artery morphogenesis 0.7122932208887363 2.1783681762995117 0.0293786371747675 1.0 0.1345243386287067 2 Q68CP9 1 +Cellular response to cold 0.7119688614985322 2.1767766852203647 0.0294972334213121 1.0 0.1348745733739655 2 Q13217 1 +Dna methylation or demethylation 0.5581637450505311 2.1726805209002307 0.029804370847362 1.0 0.1359877490371806 24 Q8NB78 1 +Regulation of glial cell migration 0.7106714239377234 2.170408098877444 0.0299759438099505 1.0 0.1365760284826052 2 Q96G23 1 +Regulation of long chain fatty acid import into cell 0.8067927343577379 2.1655357064358056 0.0303466840213859 1.0 0.1380687910802546 3 P33121 1 +Small gtpase mediated signal transduction 0.4194189496659279 2.1640613691749806 0.0304596398087282 1.0 0.1382971348173556 77 Q9NUQ9,Q15392,Q9UHD1,P57105,Q15555,P80303,Q15047,Q6IQ22,Q9UN86,O94813,P41440,Q9NP72,Q7L576,Q92538,Q14344,Q96RT1,P50570,P09601,P61586,Q96N67,Q4VCS5,Q9Y5K6,P42771,Q8IXI1,P24941,Q99653 26 +Regulation of receptor clustering 0.709373986376906 2.1640353218679547 0.0304616386555243 1.0 0.1382971348173556 2 P46109 1 +Serine transport 0.8017096566315416 2.143418468508969 0.0320795114260126 1.0 0.1441103437552852 3 Q15758 1 +Positive regulation of glucose import 0.8004542504866918 2.13794837873626 0.0325209331288784 1.0 0.1457834088609434 3 Q16625,P31751 2 +Thalamus development 0.7015893610119892 2.1257110192501742 0.0335273288524686 1.0 0.1496013927258652 2 Q02218 1 +Platelet activating factor metabolic process 0.6996432046707644 2.1161065792260083 0.0343357440611642 1.0 0.1513797497975348 2 Q7L5N7 1 +Dna methylation 0.579426169316807 2.114803334161786 0.0344467125961736 1.0 0.151699213889819 20 Q8NB78 1 +Actin crosslink formation 0.7950044746989962 2.1141676033706696 0.0345009548120684 1.0 0.1517947228888123 3 Q9UQB8 1 +Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.6989944858903603 2.1129030322526248 0.0346090682919475 1.0 0.1521621662943643 2 P23396 1 +Positive regulation of mammary gland epithelial cell proliferation 0.698021407719742 2.1080957773857167 0.0350227056283924 1.0 0.15335300906048 2 Q9NQC3 1 +Protein localization to endoplasmic reticulum 0.4926402982190542 2.1058428705564354 0.0352180035301512 1.0 0.1538925856849583 36 P61619,Q5JRA6,Q9Y5M8,P09132,O43731,P61009,Q9NQC3,Q9UHQ4,Q96HY6,P24390,P46379,P60520,Q92538,O43681 14 +Positive regulation of sequestering of calcium ion 0.7900404193973292 2.0924572595715816 0.0363976312571709 1.0 0.1585066117154571 3 P78417 1 +Negative regulation of ryanodine sensitive calcium release channel activity 0.7900404193973292 2.0924572595715816 0.0363976312571709 1.0 0.1585066117154571 3 P78417 1 +Plasma membrane organization 0.5690842167828267 2.090472620283973 0.0365753654012421 1.0 0.1589564387790755 21 Q9UQB8,P41440,Q12955,Q9Y371 4 +Dna modification 0.5126514413576656 2.085684952335565 0.0370071703855157 1.0 0.1603977899117818 31 Q03164,Q8NB78 2 +Activation of phospholipase d activity 0.787276517635438 2.080349158685757 0.0374935189107668 1.0 0.1616308762734671 3 P40616 1 +Inflammasome complex assembly 0.6915342199156653 2.075988337323103 0.0378950296613114 1.0 0.1623761870567456 2 P19525 1 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.6899124229646387 2.0679455036017824 0.0386451478779421 1.0 0.1642739331825464 2 P04439 1 +Excretion 0.8798723821142633 2.064024478896247 0.0390153955079584 1.0 0.1655182937907162 4 P09601 1 +Behavioral response to cocaine 0.7832576249188826 2.0627176308224726 0.0391394638166651 1.0 0.1658250034454928 3 Q96KQ7,P80404 2 +Negative regulation of axon extension 0.7832576249188719 2.062717630822426 0.0391394638166695 1.0 0.1658250034454928 3 Q9NQC3,Q9P265 2 +Pro b cell differentiation 0.6882906260136242 2.059896316109546 0.039408453969139 1.0 0.1661952311562449 2 O43809 1 +Lymphoid progenitor cell differentiation 0.6882906260136242 2.059896316109546 0.039408453969139 1.0 0.1661952311562449 2 O43809 1 +Ectopic germ cell programmed cell death 0.6882906260136137 2.0598963161094943 0.0394084539691439 1.0 0.1661952311562449 2 Q07812 1 +Programmed cell death involved in cell development 0.6882906260136137 2.0598963161094943 0.0394084539691439 1.0 0.1661952311562449 2 Q07812 1 +Regulation of hyaluronan biosynthetic process 0.6879662666234082 2.0582857178067515 0.0395627143709185 1.0 0.1664075825739356 2 O95782 1 +Hyaluronan metabolic process 0.6879662666234082 2.0582857178067515 0.0395627143709185 1.0 0.1664075825739356 2 O95782 1 +Hyaluronan biosynthetic process 0.6879662666234082 2.0582857178067515 0.0395627143709185 1.0 0.1664075825739356 2 O95782 1 +Paraxial mesoderm development 0.6843983133311609 2.0405524567362843 0.0412953319422091 1.0 0.170854918085594 2 Q9HCM4 1 +Response to l glutamate 0.86992162547305 2.0396991301874037 0.0413803016160905 1.0 0.1709477564347281 5 Q9UQB8 1 +Negative regulation of amyloid precursor protein biosynthetic process 0.6827765163801471 2.032481810895306 0.0421049033318521 1.0 0.1722246277984835 2 Q9NY61 1 +Regulation of dendritic spine development 0.6446149077916828 2.0293799143720412 0.0424196093101703 1.0 0.1731771453091626 14 Q9UQB8 1 +Regulation of mitotic centrosome separation 0.7749523551447077 2.0261858971857123 0.0427457382823237 1.0 0.1739702664781232 3 P52732 1 +Succinyl coa metabolic process 0.8649652200815071 2.019946577636016 0.0433889291840361 1.0 0.1756949939019819 5 Q9P2R7,A8MXV4 2 +Carnitine metabolic process 0.8648423686220543 2.0194565252773935 0.0434397915734656 1.0 0.1757898324823885 5 P11310 1 +Vesicle fusion to plasma membrane 0.773199221284878 2.018458266335446 0.0435435563938066 1.0 0.17582189150831 3 Q13277,O95295 2 +Regulation of anaphase promoting complex dependent catabolic process 0.676289328576057 2.000136781283873 0.0454854960090327 1.0 0.1809814207663749 2 P24941 1 +Regulation of dendritic spine morphogenesis 0.6928726376525305 1.9939867492510783 0.0461535026258606 1.0 0.1829575110280092 12 Q9UQB8 1 +Positive regulation of protein phosphorylation 0.4037877737796461 1.986945175810792 0.0469284726243068 1.0 0.1848854831680872 82 Q8NDZ4,Q13432,Q96HY6,Q96M27,P41440,Q9ULW0,Q00535,Q13418,Q9H7B4,P31751,P23396,P50750,P61586,Q96A49,P14635,Q96N67,Q9NQS7,O95429,P51114,P42345,P33121,Q9HAW4,Q9BZF1,P54652,P54619,P49959 26 +Torc2 signaling 0.672072656503395 1.9790594267025936 0.0478093158685255 1.0 0.1881243719003529 2 Q96A49 1 +Protein polyufmylation 0.7601323743224708 1.960685185135617 0.0499157583219811 1.0 0.1937941501882492 3 Q96HY6 1 +Cell migration involved in gastrulation 0.7595717066839633 1.958199422179716 0.0502066169176753 1.0 0.1945696236991097 3 Q4VCS5,Q9HCM4 2 +Positive regulation of synaptic vesicle endocytosis 0.6668829062601299 1.953061393646614 0.0508123208699098 1.0 0.1962040912684259 2 Q96CW1 1 +Regulation of synaptic vesicle endocytosis 0.6668829062601299 1.953061393646614 0.0508123208699098 1.0 0.1962040912684259 2 Q96CW1 1 +Positive regulation of synaptic vesicle recycling 0.6668829062601299 1.953061393646614 0.0508123208699098 1.0 0.1962040912684259 2 Q96CW1 1 +Neurotrophin trk receptor signaling pathway 0.7569417550490469 1.9465318990068063 0.0515908800232294 1.0 0.1980174819825091 3 Q96F07 1 +Regulation of protein phosphorylation 0.3499888576435342 1.9452788731588864 0.0517414234401891 1.0 0.1984763823699711 146 O15031,Q16625,Q8NDZ4,Q9UHD1,P49736,Q13432,O43823,O00410,Q96HY6,Q96M27,O94813,Q96KB5,P41440,Q9BRG1,Q9ULW0,Q9NY27,Q00535,Q13418,Q9H7B4,P31751,P23396,P14373,P50750,P61586,Q96A49,Q9H2J4,P14635,Q13217,Q07812,Q96N67,Q9NQS7,O95373,P42771,O95429,P61981,Q8IXB1,P51114,P33121,P42345,Q9HAW4,Q9BZF1,P54652,P49959,P54619,P24468,Q99653 46 +Negative regulation of production of molecular mediator of immune response 0.7563270603503959 1.9438031056903031 0.0519191991184613 1.0 0.1990391319885477 3 P09601,Q96FV9 2 +Negative regulation of dna binding transcription factor activity 0.5173838640296399 1.9424893357127797 0.0520778897126703 1.0 0.1992897022098962 26 O75381,P42771,Q96RT1,Q9UHD1,Q96J02,P09525,Q14145,Q99653,P09601 9 +Axonal transport of mitochondrion 0.8485731475588616 1.940237349757762 0.0523508513249018 1.0 0.1996516296845589 4 O60313,P07196 2 +Dendritic spine morphogenesis 0.6277437931362388 1.933744307862172 0.0531445732272679 1.0 0.2008519976955035 14 Q9UQB8 1 +Hippo signaling 0.753588525958013 1.931637960785372 0.0534042070140039 1.0 0.2013580636443256 3 Q4VCS5 1 +Positive regulation of ligase activity 0.6620175154070591 1.9286321713083123 0.0537765422127165 1.0 0.202642664361566 2 P18887 1 +Isotype switching to iga isotypes 0.7527579493835151 1.927945772599164 0.0538618715382752 1.0 0.2028448848172788 3 O96028,Q96FV9 2 +Voluntary musculoskeletal movement 0.7521090201167973 1.925060230548859 0.0542218235520541 1.0 0.2039606586461885 3 P18887,P42345 2 +Regulation of neuron differentiation 0.5727629225046953 1.915983579892146 0.055367185771465 1.0 0.2072952612811251 17 P61981,Q15648,Q8WUJ1,P61586 4 +Regulation of activin receptor signaling pathway 0.658773921505025 1.91231627246473 0.0558356398931998 1.0 0.2080762705967645 2 P67870 1 +Activin receptor signaling pathway 0.658773921505025 1.91231627246473 0.0558356398931998 1.0 0.2080762705967645 2 P67870 1 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.7465056248569852 1.9001137507076689 0.0574181935543234 1.0 0.2122452094108458 3 Q03518 1 +Peptidyl lysine dimethylation 0.831091612547022 1.8990215598703064 0.0575616413303761 1.0 0.2126467109105972 6 Q03164,Q96KQ7,Q12824 3 +Negative regulation of protein targeting to mitochondrion 0.7461501332936689 1.898529271418478 0.0576263955886351 1.0 0.2126467109105972 3 O95429 1 +Alpha beta t cell proliferation 0.7457138822446197 1.896584540113951 0.0578827925955833 1.0 0.2132243642135176 3 Q96J02 1 +Positive regulation of aspartic type peptidase activity 0.6552059682127722 1.894341634925101 0.0581796780225492 1.0 0.2141212508077574 2 Q13492 1 +Protein localization to golgi apparatus 0.7543274247006649 1.8907718032123495 0.0586548126951775 1.0 0.2154488131452451 9 Q8N2H4,P40616,Q96RL7,O14976,P83436 5 +Negative regulation of vascular endothelial growth factor receptor signaling pathway 0.653584171261756 1.8861620327504691 0.0592731231051391 1.0 0.2172217543544171 2 P18031 1 +Peptidyl glutamic acid modification 0.8343989773203024 1.8837258811598512 0.0596020637337912 1.0 0.2181776115878096 4 P38435 1 +Guanine metabolic process 0.6529354524813488 1.8828885734832643 0.0597154700698134 1.0 0.218429946074932 2 O60341 1 +Negative regulation of calcium ion dependent exocytosis 0.6526110930911433 1.881251498149268 0.0599377153676843 1.0 0.218532159729878 2 O00186 1 +Negative regulation of adenylate cyclase activity 0.652611093091142 1.8812514981492616 0.0599377153676852 1.0 0.218532159729878 2 P08754 1 +Negative regulation of lyase activity 0.652611093091142 1.8812514981492616 0.0599377153676852 1.0 0.218532159729878 2 P08754 1 +Gamma aminobutyric acid signaling pathway 0.6526110930911412 1.8812514981492567 0.0599377153676858 1.0 0.218532159729878 2 P55011 1 +Protein insertion into er membrane 0.6703316229650007 1.8767767293869924 0.0605487011534511 1.0 0.2202583643322021 12 P46379,Q9P0I2,P61619 3 +Regulation of urine volume 0.6509892961401204 1.8730626756450568 0.0610597306744238 1.0 0.2208819580221509 2 P04899 1 +Mitochondrion distribution 0.8282303391920147 1.8724549712275065 0.0611436859722929 1.0 0.2209173448045732 5 O75153,Q9BUK6 2 +Regulation of intracellular steroid hormone receptor signaling pathway 0.5219328576639538 1.857893563207325 0.063184130656416 1.0 0.2254926522872672 23 Q9NUQ7,O75376,P38398,Q86X55,Q96HY6,Q13547,P61586 7 +Nuclear transcribed mrna catabolic process exonucleolytic 0.639683407406981 1.851618361854208 0.0640806444350983 1.0 0.2279292661028538 13 Q96B26,Q9NQT5,P62487,Q15024,Q13868,Q969T7,Q6PGP7 7 +Mitotic dna replication checkpoint signaling 0.7342634652822801 1.8454259581381889 0.0649755999686938 1.0 0.2303451540672123 3 Q9HAW4,Q9Y619 2 +Negative regulation of ion transmembrane transporter activity 0.7734338789462594 1.8435612994022943 0.0652471004613586 1.0 0.2305016231411328 8 Q96PU5,Q12955,P78417 3 +Positive regulation of activated t cell proliferation 0.7329818514426032 1.8396863899311584 0.0658142928353853 1.0 0.2317791973081244 3 P23396 1 +Histone h3 k9 acetylation 0.8229638395593191 1.8379388575492992 0.0660714154374733 1.0 0.2319153659661632 4 Q03164 1 +Arf protein signal transduction 0.7319922128487829 1.835252569620247 0.0664682752180891 1.0 0.2319153659661632 3 Q15555,Q92538 2 +Amine catabolic process 0.8151446257153453 1.833894468442812 0.0666696608508448 1.0 0.2319857943566061 6 P49419 1 +Positive regulation of smooth muscle contraction 0.7315771505089301 1.8333925165546223 0.0667442196987395 1.0 0.2321191484202636 3 P61586 1 +Neuron projection organization 0.5364580636482877 1.8254499784204792 0.067933153159609 1.0 0.2352323130488947 20 Q9UQB8,Q05086 2 +Clathrin dependent endocytosis 0.6084703451644528 1.823641721119077 0.0682062547984243 1.0 0.2357956115697282 14 P50570,O95782,Q13432,Q96CW1,Q13492,O14976,P63010 7 +Nucleotide transport 0.5746799664987903 1.8182650917898124 0.0690236254947895 1.0 0.2377233037202269 16 Q86VD7,O43808,Q9BSK2,Q8TDW0,O00400,Q08722,P41440 7 +Phosphatidylinositol dephosphorylation 0.8177522668576771 1.8170152855254564 0.069214772864433 1.0 0.2381255826904177 4 Q13614,Q9C0I1 2 +Phospholipid dephosphorylation 0.8177522668576771 1.8170152855254564 0.069214772864433 1.0 0.2381255826904177 4 Q13614,Q9C0I1 2 +Triglyceride metabolic process 0.6583863108703838 1.8142469862379704 0.0696397093044556 1.0 0.2386553477717073 12 Q9UBV2,Q9BZK7,P33121 3 +Atp synthesis coupled proton transport 0.6575986043731917 1.810114109463424 0.0702780933808997 1.0 0.2386553477717073 12 P00846,O75964 2 +Calmodulin dependent kinase signaling pathway 0.6383392799221501 1.80899656847948 0.0704515364656526 1.0 0.2386553477717073 2 Q13131 1 +Protein trimerization 0.8151205778149346 1.8064364733883873 0.0708501886978743 1.0 0.2386553477717073 4 Q99720 1 +Postsynaptic cytoskeleton organization 0.8140927618719356 1.8023025324498725 0.0714978203233012 1.0 0.2386553477717073 4 Q9Y4F1 1 +Peptidyl proline modification 0.4884839689743165 1.7960512446620345 0.0724863674527915 1.0 0.2391549190307113 28 Q96AY3,O95302,Q32P28,Q9NWM8,P26885 5 +Regulation of plasma membrane organization 0.7229423019580852 1.7946338954610832 0.072712049019231 1.0 0.2396056512434124 3 Q9Y371 1 +Regulation of vesicle size 0.7219338092147886 1.7900994749585946 0.073437921205089 1.0 0.241572180119115 3 Q96CW1,Q13492 2 +Cellular response to leucine starvation 0.721609344581442 1.788640269686018 0.0736727681034197 1.0 0.2418732098883591 3 Q9P2J5,P42345 2 +Trna catabolic process 0.7319013086943961 1.78731993228599 0.073885794263441 1.0 0.2418732098883591 9 Q9NQT5,Q96B26,Q99575 3 +Protein k6 linked ubiquitination 0.7212848799480843 1.787180901276674 0.0739082551095369 1.0 0.2418732098883591 3 P38398,Q16763 2 +G0 to g1 transition 0.7210490636933746 1.7861201509678823 0.0740798060881924 1.0 0.2418732098883591 3 O14757 1 +Regulation of g0 to g1 transition 0.7210490636933746 1.7861201509678823 0.0740798060881924 1.0 0.2418732098883591 3 O14757 1 +Ventral spinal cord development 0.63314952967888 1.7826167194232214 0.0746487162970517 1.0 0.2429876405482283 2 Q14203 1 +Female sex differentiation 0.7003549496782391 1.777351394771972 0.0755104425215078 1.0 0.2452940642965412 10 O75874,Q07812,Q05086,O94813 4 +Ammonium ion metabolic process 0.8045936386370944 1.776593660337465 0.0756351194714026 1.0 0.2455745440110519 5 P49419 1 +Dendrite morphogenesis 0.4797617204117543 1.767754615541166 0.0771019351472284 1.0 0.2485301391264421 29 Q9UQB8,Q05086,Q9Y4F1 3 +Inositol phosphate catabolic process 0.7166491073517856 1.7663125846047112 0.0773434214443589 1.0 0.2488508075201221 3 Q13614 1 +Nephron morphogenesis 0.8049475934355069 1.7654631000021896 0.0774859665657397 1.0 0.2491842880623135 4 Q13418 1 +Negative regulation of viral process 0.5423200662623062 1.7645720164350278 0.0776357219872836 1.0 0.2495406096590762 18 Q15047 1 +Sensory perception of pain 0.7156884090406784 1.7619838326499857 0.0780720291006624 1.0 0.2504403697640679 3 Q00535 1 +Regulation of membrane depolarization 0.7958600455218519 1.7547011266943504 0.0793104432166926 1.0 0.2528551836694152 6 Q96PU5 1 +Dendritic cell apoptotic process 0.6276354200454082 1.7545290787612071 0.079339891767185 1.0 0.2528551836694152 2 P07948 1 +Neuropeptide signaling pathway 0.627635420045404 1.7545290787611854 0.0793398917671888 1.0 0.2528551836694152 2 Q9Y3E5 1 +Sensory perception of mechanical stimulus 0.5957807103049709 1.750701607093053 0.0799973224723293 1.0 0.2545766754881977 14 P49419 1 +Positive regulation of glucose transmembrane transport 0.8007140538786125 1.7483752206488192 0.0803990757815826 1.0 0.2556012304996619 4 Q86YS7,Q16625,P31751 3 +Histone lysine demethylation 0.7942031708531867 1.7478760199961934 0.0804854980346145 1.0 0.2556222609864854 6 Q8NB78,Q9Y2K7 2 +Protein demethylation 0.7942031708531867 1.7478760199961934 0.0804854980346145 1.0 0.2556222609864854 6 Q8NB78,Q9Y2K7 2 +Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 0.7121998702141356 1.7462534232508953 0.0807669253967873 1.0 0.2563889613933695 3 P78417,P28161 2 +Cellular component maintenance 0.6936263577745166 1.744681510807183 0.0810403234470704 1.0 0.2571294264496946 10 Q9BRK5,Q9C0E8 2 +Axoneme assembly 0.7996684049026787 1.744151426670327 0.0811326886213441 1.0 0.257246963982638 4 Q15555,Q9NVR5 2 +Regulation of b cell differentiation 0.625040544923771 1.741290836778973 0.0816326115824164 1.0 0.2580142298540966 2 Q5JVF3 1 +Negative regulation of lipid catabolic process 0.7110294436941031 1.7409717343929736 0.0816885332316199 1.0 0.2580358697641802 3 Q96HJ9 1 +Detection of biotic stimulus 0.7102516925254152 1.7374609291513563 0.0823058446747631 1.0 0.2584564906796727 3 P04439 1 +Fat cell differentiation 0.5050255837626556 1.7360757865304712 0.0825504350889754 1.0 0.2589645736449752 23 Q9NZ08,P31751,Q86X55,Q9BZK7,Q8N4Q0,Q8TDW0,Q9BRK5 7 +Intra golgi vesicle mediated transport 0.5442309576937076 1.7342465219531162 0.0828743516992212 1.0 0.2593517816244313 17 Q9UP83,O14653,O95249,Q14746 4 +Golgi to endosome transport 0.7702886032280094 1.7329511071688914 0.0831043593522014 1.0 0.259944592778419 7 Q96RL7,O95782,Q8N2H4,Q7Z3U7 4 +Mitochondrial atp synthesis coupled proton transport 0.6669231455692909 1.7309661572236266 0.0834578007166446 1.0 0.2604871856763341 11 P00846,O75964 2 +Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway 0.6227700291923429 1.7296968239038044 0.0836844564661065 1.0 0.2604871856763341 2 P04899 1 +Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway 0.6227700291923429 1.7296968239038044 0.0836844564661065 1.0 0.2604871856763341 2 P04899 1 +Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process 0.6227700291923429 1.7296968239038044 0.0836844564661065 1.0 0.2604871856763341 2 P04899 1 +Positive regulation of camp dependent protein kinase activity 0.6227700291923407 1.729696823903792 0.0836844564661087 1.0 0.2604871856763341 2 Q9Y4G8 1 +Cellular response to epinephrine stimulus 0.6227700291923406 1.7296968239037895 0.0836844564661092 1.0 0.2604871856763341 2 P17252 1 +Response to epinephrine 0.6227700291923406 1.7296968239037895 0.0836844564661092 1.0 0.2604871856763341 2 P17252 1 +Negative regulation of lymphocyte mediated immunity 0.707396759276205 1.7245660964660676 0.084605697776309 1.0 0.2625891957146489 3 P04439 1 +Negative regulation of autophagosome assembly 0.7071206103636765 1.7233181960992932 0.0848309989878477 1.0 0.2628484401129471 3 O75396 1 +Histone h2a acetylation 0.7456713785327164 1.720446071628415 0.0853513884775813 1.0 0.2637534947358352 8 Q86UY6 1 +Glycerol 3 phosphate metabolic process 0.6195264352902912 1.7131171658287625 0.0866909866130947 1.0 0.2667350913753529 2 Q9HCL2 1 +N terminal protein amino acid modification 0.7907638586880327 1.7081318562917378 0.0876118791120088 1.0 0.2691806703076876 4 Q86UY6 1 +Positive regulation of neuron differentiation 0.7426398754935437 1.7069425443637112 0.0878327321120773 1.0 0.2697244695276395 8 Q8WUJ1 1 +Positive regulation of dna demethylation 0.6182289977294795 1.7064798600474036 0.0879187729548829 1.0 0.2697354691326533 2 Q93009 1 +Establishment of pigment granule localization 0.7031148604801939 1.7052042798525755 0.0881563320946177 1.0 0.2703202976792499 3 P62820,Q15907 2 +Glycosylation 0.4020947717574252 1.7042202803212063 0.0883399417683761 1.0 0.2705180445079252 51 O60476,P26572,Q9UHD1,Q14746,Q9UP83,Q13724,Q99653,Q96AA3,Q9HC07,Q16706,O60762,Q9NYU2,Q9H553,Q9NR45,O60502,Q9BT22,P83436 17 +Histone h4 r3 methylation 0.6172559195588663 1.701499866507005 0.0888491628685095 1.0 0.2719387182683574 2 O14744 1 +Tail anchored membrane protein insertion into er membrane 0.7124619221436326 1.6970563776247871 0.0896860023412855 1.0 0.2741071235678794 9 P46379,Q9P0I2 2 +Rrna 3 end processing 0.761570454153892 1.6956070625746626 0.0899603193774938 1.0 0.2746834156016327 7 Q96B26,Q9NQT5 2 +Regulation of carbohydrate biosynthetic process 0.5861686826451096 1.695240019124313 0.0900298980715652 1.0 0.274764486180056 14 Q9BYT8,P11310,Q92520,P31751 4 +Regulation of 3 utr mediated mrna stabilization 0.6159584819980515 1.694857213134664 0.0901025109329114 1.0 0.274764486180056 2 Q86W50 1 +Peptidyl proline hydroxylation 0.7812632287804802 1.6944652623373773 0.0901769072633664 1.0 0.274764486180056 6 Q32P28 1 +Neutral amino acid transport 0.7870809630661983 1.69320849683038 0.0904157878344611 1.0 0.274764486180056 4 Q15758 1 +Corpus callosum development 0.699870214146657 1.6905156352296105 0.0909293495889853 1.0 0.2755809544511605 3 Q96P11,Q00535 2 +Development of primary female sexual characteristics 0.7106812691095258 1.6887634340741984 0.0912647738179361 1.0 0.276035005230264 9 O75874,Q07812,Q05086,O94813 4 +Negative regulation of cation channel activity 0.7822195431899397 1.6852317304823663 0.0919438713940383 1.0 0.2773273193107703 5 Q12955,P78417 2 +Nuclear ncrna surveillance 0.7779993770027709 1.680964388572571 0.0927698318579437 1.0 0.2792685821813851 6 Q96B26,Q9NQT5 2 +Positive regulation of release of sequestered calcium ion into cytosol 0.7809113784999628 1.6798728307024124 0.0929820610063418 1.0 0.2795134128609225 5 Q07812,P78417 2 +Cellular carbohydrate metabolic process 0.3946298717701915 1.6725908581777746 0.0944078677999495 1.0 0.2826059818348023 54 P11310,P48735,Q13794,P85037,O75376,O75874,Q92520,Q7LGA3,Q10713,Q13614,Q9BYT8 11 +Response to increased oxygen levels 0.7345439722301328 1.670827364834528 0.0947557817496016 1.0 0.2834703793962753 8 P00846 1 +Mannose metabolic process 0.7810881555833855 1.668894209007058 0.0951383474836651 1.0 0.2836878153596335 4 P34949 1 +Dendritic spine development 0.5015657030248358 1.6656093481460068 0.0957912480039713 1.0 0.2847882833800099 22 Q9UQB8 1 +Cytoplasmic pattern recognition receptor signaling pathway 0.6285263726968467 1.6568388497870008 0.0975520601757962 1.0 0.2885126950536244 12 Q9NUD5,Q96RT1,O43657 3 +Replication born double strand break repair via sister chromatid exchange 0.6917864671826763 1.653858527907552 0.0981562607609682 1.0 0.2897645190943607 3 P18887 1 +Nuclear transcribed mrna catabolic process deadenylation dependent decay 0.486957197256438 1.6530188421875458 0.0983270288846887 1.0 0.2900013568302558 24 Q96B26,P67809,Q9NQT5,P62487,Q15024,Q96C86,Q13868,O15514,Q969T7 9 +Response to ketone 0.4488196747313214 1.6524495188743542 0.0984429479251909 1.0 0.29020962927233 34 Q13126,Q9H7B4,P07196,O43823,O94813,O95831,Q05086 7 +Regulation of sequestering of triglyceride 0.6075251378527311 1.651607867133238 0.0986145152264335 1.0 0.2904480848462221 2 Q9BZF1 1 +Sequestering of triglyceride 0.6075251378527311 1.651607867133238 0.0986145152264335 1.0 0.2904480848462221 2 Q9BZF1 1 +Forebrain cell migration 0.650840407798504 1.6494029098579397 0.099065118994059 1.0 0.2913465747016759 11 Q8WXH0,O94813,Q02218,P61586,O94901 5 +Response to reactive oxygen species 0.4517695215885139 1.645952819162566 0.0997734731036512 1.0 0.2927884317362104 33 Q99720,P09601,Q05086 3 +Regulation of pattern recognition receptor signaling pathway 0.5465131098042043 1.6443785897888694 0.1000980248119181 1.0 0.2933186055966156 16 Q96RT1,Q9NUD5,Q9NPR9,P41440,O43657 5 +Cellular response to alkaloid 0.7735933280962602 1.6384339357346982 0.1013312048375068 1.0 0.2958596209422645 4 Q96KQ7,P28161 2 +Positive regulation of lipase activity 0.7677033864798976 1.638303253091396 0.101358449418448 1.0 0.2958596209422645 6 P40616,P61586 2 +Viral gene expression 0.4391209042325509 1.638122264554274 0.1013961913540528 1.0 0.2958596209422645 36 P26572,Q13724,P61009,Q13547,Q16706,P14373,P50750,Q12824 8 +Regulation of phosphatidylinositol 3 kinase signaling 0.7704567057513497 1.636982195204291 0.101634189874844 1.0 0.2960748614544116 5 Q8NDZ4,Q05086 2 +Positive regulation of alcohol biosynthetic process 0.6042815439506917 1.6349414323619886 0.102061325834579 1.0 0.2962820825935985 2 Q13131 1 +Positive regulation of cholesterol biosynthetic process 0.6042815439506917 1.6349414323619886 0.102061325834579 1.0 0.2962820825935985 2 Q13131 1 +Positive regulation of steroid metabolic process 0.6042815439506917 1.6349414323619886 0.102061325834579 1.0 0.2962820825935985 2 Q13131 1 +Positive regulation of cholesterol metabolic process 0.6042815439506917 1.6349414323619886 0.102061325834579 1.0 0.2962820825935985 2 Q13131 1 +Positive regulation of steroid biosynthetic process 0.6042815439506917 1.6349414323619886 0.102061325834579 1.0 0.2962820825935985 2 Q13131 1 +Regulation of histone h4 k16 acetylation 0.6875588656819751 1.6346541007890316 0.1021215795139971 1.0 0.2962820825935985 3 Q12824 1 +Regulation of myotube differentiation 0.7725686113852296 1.6342649880263245 0.1022032219223181 1.0 0.2963847169010275 4 Q13547,Q9BYT8 2 +N glycan processing 0.7724515528534426 1.633788683575111 0.1023032293106167 1.0 0.2964063713088244 4 O60476 1 +Dendritic spine maintenance 0.6868611126176694 1.6314823249068435 0.1027885864051216 1.0 0.2967774252072281 3 Q13614 1 +Regulation of lipid catabolic process 0.6983612898908875 1.6312830669474936 0.1028306046599758 1.0 0.2967774252072281 9 P31751,O75874,P50416,Q8WTV0,Q96HJ9,P11802 6 +Negative regulation of androgen receptor signaling pathway 0.7717009923449873 1.63073438267517 0.1029463783246042 1.0 0.2967932041167485 4 O75376 1 +Motor neuron apoptotic process 0.6033084657800787 1.629938160944668 0.1031145673023123 1.0 0.2970107545587289 2 O75312 1 +Meiotic cell cycle checkpoint signaling 0.6026597469996652 1.6266018037402306 0.1038216959972417 1.0 0.2982429527167403 2 Q08J23 1 +Negative regulation of cell size 0.6856108783138761 1.625797645207636 0.103992709471343 1.0 0.2986003123592218 3 P61586 1 +Rna polymerase i preinitiation complex assembly 0.7655949588178589 1.6170002084909303 0.1058782359051837 1.0 0.3030634402183231 5 P17480,Q12824 2 +Transcription initiation from rna polymerase i promoter 0.7655949588178589 1.6170002084909303 0.1058782359051837 1.0 0.3030634402183231 5 P17480,Q12824 2 +Sensory perception 0.4546258948471784 1.6137072129130552 0.1065909486869673 1.0 0.3045591513330566 31 P62072,Q13432,P49419,Q9BRK0 4 +Chemical synaptic transmission postsynaptic 0.7207519001227447 1.6091379745219752 0.1075861753015017 1.0 0.3063097951028533 8 Q9UQB8 1 +Regulation of postsynaptic membrane potential 0.7207519001227447 1.6091379745219752 0.1075861753015017 1.0 0.3063097951028533 8 Q9UQB8 1 +Motor neuron axon guidance 0.7626557202865676 1.6049091615755258 0.1085137970561564 1.0 0.307931073518087 5 P63000,Q00535,O94813 3 +Phosphatidylglycerol acyl chain remodeling 0.5977943561466044 1.601558112260474 0.1092533598104552 1.0 0.3095431326606707 2 Q8NF37 1 +Negative regulation of cellular amide metabolic process 0.3735529803281278 1.599888212709185 0.1096233846961816 1.0 0.3100488056482934 77 P60228,Q14011,Q10713,Q969T7,P05198,Q8WU17,P62487,Q16799,P00374,P23396,Q13868,Q92945,P26196,P67809,Q9NQT5,Q15024,Q96C86,Q9NQC3,Q9Y6M1,P51114,Q96B26,Q9HCE1,O15514,O95453,P19525,P49458 26 +Protein insertion into er membrane by stop transfer membrane anchor sequence 0.7581308816588941 1.5985480473494922 0.1099210613187986 1.0 0.3107477135076011 6 Q9P0I2 1 +Regulation of gluconeogenesis 0.6911172209216816 1.5974070780909138 0.1101749957256985 1.0 0.3108880191182849 9 P11310 1 +Exonucleolytic catabolism of deadenylated mrna 0.6905560119723456 1.5947804403325874 0.1107613424747611 1.0 0.3117855869738191 9 Q96B26,Q9NQT5,Q969T7 3 +Hippocampus development 0.5687959698981282 1.594601915143697 0.1108012840744194 1.0 0.3117855869738191 14 P07196,P18887,P23634,Q13547,A0AVT1,O14949,Q02218,P46109,Q00535,P43034 10 +Exploration behavior 0.677880308799908 1.5906064157954007 0.1116981797028988 1.0 0.3128933416207408 3 Q05086 1 +Regulation of glucose metabolic process 0.4910245353475476 1.5905727732945758 0.1117057558986316 1.0 0.3128933416207408 22 P11310,Q13794,P85037,Q92520,Q9BYT8 5 +Dna unwinding involved in dna replication 0.5525113453509685 1.5861078322423368 0.1127148504708603 1.0 0.3148937340236946 15 Q96RR1,P25205,P46063,Q9BRX5,Q9BRT9 5 +T cell selection 0.6763216130442767 1.5835026152318634 0.1133069510586897 1.0 0.3159933858908836 3 P61586 1 +Positive regulation of peptidyl serine phosphorylation 0.5668481949267177 1.5832912132967012 0.113355104710779 1.0 0.3159933858908836 14 O95429,Q9H7B4 2 +Positive regulation of chromatin binding 0.6761842959117563 1.582876659840243 0.1134495795186338 1.0 0.3161139948423913 3 Q71SY5,O60341 2 +Histone h4 acetylation 0.4898851822654929 1.5824520520570418 0.1135464099488514 1.0 0.3161139948423913 22 Q03164,Q86UY6,Q12824 3 +Positive regulation of calcium ion transport into cytosol 0.7537349915280149 1.580264244111383 0.1140463646686287 1.0 0.317229793063556 6 Q07812,P78417 2 +Negative regulation of muscle cell apoptotic process 0.7564939032606425 1.579536626540016 0.114213022297865 1.0 0.3174180567636109 5 P09601 1 +2 oxoglutarate metabolic process 0.6597510076214097 1.5792772985618624 0.1142724665574856 1.0 0.3174455423969008 10 Q8TD30,O75874,Q02218,P48735 4 +Positive regulation of macroautophagy 0.5353294622403387 1.5749335073049655 0.1152717934030727 1.0 0.318976720751656 16 P09601,Q8TBX8,Q9Y371,O15269 4 +Protein retention in er lumen 0.757318378988159 1.5721063612650363 0.1159258864810772 1.0 0.319957444548807 4 P24390 1 +Maintenance of protein localization in endoplasmic reticulum 0.757318378988159 1.5721063612650363 0.1159258864810772 1.0 0.319957444548807 4 P24390 1 +Positive regulation of actin filament polymerization 0.6121876089865388 1.5701556218809003 0.1163789110386048 1.0 0.3203528368223731 12 Q9UQB8,O95429,P61586 3 +Positive regulation of torc1 signaling 0.67229072031148 1.5651194507445594 0.117554903645948 1.0 0.3220011197585455 3 Q9P2J5,Q96EE3 2 +Female meiosis i 0.5903340901719049 1.5630892255496092 0.1180316095297051 1.0 0.3228278836393748 2 Q15645 1 +Regulation of cellular carbohydrate metabolic process 0.4662207370240819 1.5543977435331695 0.1200895711527438 1.0 0.3271857029141434 26 P11310,Q13794,P85037,O75376,Q92520,Q9BYT8 6 +Lipoprotein localization 0.7500006985611277 1.5527651127031512 0.1204792602272488 1.0 0.3278632714595396 5 Q13432,A6NIH7 2 +Regulation of metallopeptidase activity 0.6693366642530639 1.5516364369322238 0.1207492395678739 1.0 0.3284054517532833 3 Q96HY6 1 +Regulation of dna primase activity 0.668943765684884 1.5498424856256905 0.1211793269048007 1.0 0.3293486500433404 3 Q9BRT9 1 +Viral transcription 0.5312047478349695 1.5492772833327138 0.1213150781940421 1.0 0.3295189416426388 16 Q12824,P14373,P50750 3 +Purine nucleotide transport 0.5848166285982185 1.54901224800448 0.1213787758032709 1.0 0.3295189416426388 13 Q86VD7,O43808,Q8TDW0,Q08722,O00400,P41440 6 +Negative regulation of membrane potential 0.6685127552407553 1.547874340230014 0.121652553643341 1.0 0.3299349105161908 3 Q13794 1 +Limbic system development 0.5091199213789599 1.5467494371851551 0.1219236769731688 1.0 0.3305302897545999 18 P07196,P18887,P23634,Q07812,Q13547,A0AVT1,O14949,Q02218,P46109,Q00535,P43034 11 +Anaphase promoting complex dependent catabolic process 0.6529127936394526 1.5457316925674782 0.1221693798686467 1.0 0.3308968324636289 10 Q9UJX3,Q9H1A4,Q9UJX4,P24941,Q16763 5 +Protein ufmylation 0.7508523905334574 1.5456914070544372 0.1221791135139935 1.0 0.3308968324636289 4 Q96HY6 1 +Response to arsenic containing substance 0.6075399520436544 1.5454422492977835 0.1222393276111826 1.0 0.3308968324636289 12 P09601,P78417 2 +Regulation of intracellular estrogen receptor signaling pathway 0.5840980679157017 1.545020439634794 0.1223413194583544 1.0 0.3308968324636289 13 P38398,Q86X55,Q9NUQ7,Q96HY6 4 +Negative regulation of retinoic acid receptor signaling pathway 0.5867661368796572 1.5446636372691014 0.1224276447156498 1.0 0.3308968324636289 2 P27797 1 +Regulation of transcription involved in g1 s transition of mitotic cell cycle 0.6675781264965195 1.5436058634770518 0.1226838437014068 1.0 0.3313291326944402 3 Q00535 1 +Negative regulation of calcineurin mediated signaling 0.7499496618111345 1.5420009546709257 0.1230733616055701 1.0 0.331961243976961 4 Q99653,P42345 2 +Negative regulation of calcium mediated signaling 0.7499496618111345 1.5420009546709257 0.1230733616055701 1.0 0.331961243976961 4 Q99653,P42345 2 +Regulation of arp2 3 complex mediated actin nucleation 0.6660709191682247 1.5367206033830942 0.1243617434693298 1.0 0.3343102512230494 3 Q7L576 1 +Negative regulation of leukocyte mediated immunity 0.7484903835864695 1.536033965846162 0.1245300501245174 1.0 0.3346222739503602 4 P09601,P04439 2 +Carbohydrate mediated signaling 0.748401219787797 1.5356693234891774 0.1246195024267269 1.0 0.3347222358681814 4 P17480,Q12824 2 +Positive regulation of neurogenesis 0.4383566277576118 1.5328017447550066 0.1253247106280222 1.0 0.3361935076562438 33 O15031,P07196,Q9UQB8,Q13547,Q16706,O94813,P55209 7 +Regulation of glial cell apoptotic process 0.6651524983776738 1.53252397989996 0.1253931847462321 1.0 0.3362363924170629 3 P17252,Q00535 2 +Protein k63 linked ubiquitination 0.6273883919554225 1.529893264814833 0.1260431507737682 1.0 0.3374143016534724 11 P14373,Q96J02,Q9C0C9 3 +Ribonucleoside triphosphate metabolic process 0.4266789724975928 1.5284049042528949 0.126412037937778 1.0 0.3376977267245257 36 O75964,O75414,P17812,P56134,O60313,P00846,Q9UJZ1,P61586 8 +Response to amino acid starvation 0.6270842943940746 1.5283400061484749 0.126428141908693 1.0 0.3376977267245257 11 Q9P2J5,P42345,Q96EE3,Q9Y371,P19525,P05198 6 +Response to bacterium 0.3815208909220139 1.5249128708742703 0.1272808311353741 1.0 0.3391684709871908 53 Q6PD62,Q9Y4Y9,Q13451,Q9NUQ9,Q96RT1,Q9NZ08,Q96EE3,O43823,Q9UQB8,P51812,Q86U42,P61586,P11802 13 +Necroptotic signaling pathway 0.582549464807001 1.5228666951139185 0.1277920596543813 1.0 0.3398596554616556 2 P49327 1 +Regulation of macrophage differentiation 0.5825494648069992 1.5228666951139096 0.1277920596543835 1.0 0.3398596554616556 2 P17252 1 +Positive regulation of macrophage differentiation 0.5825494648069992 1.5228666951139096 0.1277920596543835 1.0 0.3398596554616556 2 P17252 1 +Er associated misfolded protein catabolic process 0.7212212677080162 1.5217669149259812 0.1280674942219226 1.0 0.3402696511072023 7 P46379,Q9Y679 2 +Protein hydroxylation 0.5797091373885158 1.5206277640392802 0.1283532754191068 1.0 0.3404683570744506 13 Q96AY3,Q12797,Q32P28,P13674,Q9H267,O00469 6 +Regulation of t cell migration 0.6618648759424289 1.5174950853603175 0.1291417333893301 1.0 0.3421347990455122 3 P61586 1 +Positive regulation of protein polymerization 0.4528792084502641 1.5163162757137685 0.1294393981041568 1.0 0.342781638799185 28 Q16625,O95429,P62993,P63000,P42345,P23396,Q14203,Q9UQB8,P36405,Q15691,P61586 11 +Circadian rhythm 0.4066741275912149 1.5107662725555986 0.1308480106453129 1.0 0.3453697388520291 43 Q9UNS1,Q03164,O75376,P43490,Q13547,Q9Y2K7,Q05086 7 +Regulation of fat cell differentiation 0.698055320272023 1.507242084689112 0.1317486165812265 1.0 0.347460534301909 8 Q8N4Q0 1 +Positive regulation of nervous system development 0.4316845525883851 1.5058114622159615 0.1321155800197395 1.0 0.3481824641206111 34 O15031,P42345,P07196,Q9UQB8,Q13547,Q16706,O94813,P55209 8 +Dna dependent dna replication maintenance of fidelity 0.5529735800152024 1.502595397304236 0.1329434110191307 1.0 0.3498913274398322 14 P50750,Q9UNS1,Q86V81,Q7Z7L1 4 +Synaptic vesicle transport 0.6219158455444098 1.5019294905923672 0.1331153194633065 1.0 0.3500561315607315 11 Q96A57,O00203,P50570,O95295,Q9Y2T2,Q13492,Q00535 7 +Striated muscle cell differentiation 0.41755862010931 1.5011487339246077 0.1333170963090548 1.0 0.3502963541846167 38 P11310,P41440 2 +Atp biosynthetic process 0.4831252755431934 1.4951446480503885 0.1348766956868949 1.0 0.3532379855152286 21 P00846,O75964 2 +Regulation of phospholipid catabolic process 0.6562747031632432 1.4919184277357092 0.135720531130481 1.0 0.3547228569652636 3 O75874 1 +Modification of postsynaptic actin cytoskeleton 0.7343559671398272 1.4881334866120086 0.1367156938985183 1.0 0.3563986526708547 5 Q9UQB8 1 +Regulation of aspartic type peptidase activity 0.6554185593770261 1.487999015237381 0.1367511533351484 1.0 0.3563986526708547 3 P49755,Q13492 2 +Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process 0.6554185593770261 1.487999015237381 0.1367511533351484 1.0 0.3563986526708547 3 P49755,Q13492 2 +Negative regulation of mrna catabolic process 0.4645453760832654 1.4868729923912634 0.1370483585552042 1.0 0.3570279727143711 24 P67809,Q92804,Q99729,Q14011,P16989,P98175 6 +Cellular response to hydrogen peroxide 0.4999021064206476 1.485984120944429 0.13728332116188 1.0 0.3571251295017345 18 Q99720 1 +Amyloid precursor protein catabolic process 0.5500378288105185 1.485497365945517 0.1374121206442875 1.0 0.3571251295017345 14 Q9NQC3,Q15392,Q16799 3 +Organism emergence from protective structure 0.7309805545080014 1.485384638344165 0.1374419626044893 1.0 0.3571251295017345 6 Q9BZK7,Q12824 2 +Positive regulation of erad pathway 0.6548195671666777 1.485256490372498 0.1374758928116262 1.0 0.3571251295017345 3 P46379 1 +Nk t cell differentiation 0.574764839442095 1.4825708146196437 0.1381884760968723 1.0 0.3580094150984822 2 O00203 1 +Antigen processing and presentation of lipid antigen via mhc class ib 0.574764839442095 1.4825708146196437 0.1381884760968723 1.0 0.3580094150984822 2 O00203 1 +Synaptic vesicle recycling via endosome 0.574764839442095 1.4825708146196437 0.1381884760968723 1.0 0.3580094150984822 2 O00203 1 +Regulation of nk t cell differentiation 0.574764839442095 1.4825708146196437 0.1381884760968723 1.0 0.3580094150984822 2 O00203 1 +Response to food 0.7323023456812758 1.4796377044789584 0.138969958616518 1.0 0.3592580931789406 5 Q9UMX5 1 +Dna replication checkpoint signaling 0.7345017851346988 1.478759224362859 0.1392046773481037 1.0 0.3597197108075645 4 Q9HAW4,Q9Y619,Q9UNS1 3 +Protein insertion into membrane 0.4408389047416617 1.4774050035118391 0.1395671057418694 1.0 0.3605108384606516 30 Q9P0I2,P61619,P62072,P46379,Q15070,Q9P0J0 6 +Dendrite development 0.4003611066045066 1.476880974708106 0.1397075456374112 1.0 0.3607281488727354 44 Q9UQB8,Q96PU5,Q05086,Q9Y4F1 4 +Regulation of superoxide anion generation 0.652822842310187 1.4761123336491633 0.1399137384240543 1.0 0.3608525946487887 3 P08754,Q9NY61 2 +Regulation of carbohydrate metabolic process 0.4316351247851129 1.4760713695845895 0.1399247338600673 1.0 0.3608525946487887 33 P11310,P31751,Q13794,P85037,O75376,Q92520,Q9BYT8 7 +Histone h4 k16 acetylation 0.6910362289045471 1.475654947143992 0.1400365463031216 1.0 0.3609956199669205 8 Q03164 1 +Skeletal muscle acetylcholine gated channel clustering 0.6525471403462643 1.4748494955788745 0.1402530109394355 1.0 0.3612628822187471 3 P46109 1 +Regulation of steroid hormone biosynthetic process 0.5731430424910753 1.4741675667182266 0.140436480048141 1.0 0.3612996350154279 2 P16435 1 +Regulation of hormone biosynthetic process 0.5731430424910753 1.4741675667182266 0.140436480048141 1.0 0.3612996350154279 2 P16435 1 +Negative regulation of hormone metabolic process 0.5731430424910726 1.4741675667182126 0.1404364800481448 1.0 0.3612996350154279 2 O60678 1 +Pattern recognition receptor signaling pathway 0.4588901576597073 1.4702593237398836 0.1414915331329593 1.0 0.3635759170676846 25 Q96RT1,Q9NUD5,Q96J02,Q9NPR9,Q9NQC3,P41440,O43657 7 +Polyamine metabolic process 0.5721699643204594 1.46912435009562 0.1417990642791671 1.0 0.3637824612624528 2 P49366 1 +Spermidine metabolic process 0.5721699643204594 1.46912435009562 0.1417990642791671 1.0 0.3637824612624528 2 P49366 1 +Osteoblast differentiation 0.409381521393628 1.4655111799324223 0.1427815043942404 1.0 0.3652788806507604 40 Q9UHQ4,Q9H6W3,Q86V81,Q13418 4 +Ribonucleoside triphosphate biosynthetic process 0.4505140867891866 1.4645284006916857 0.1430496289729235 1.0 0.365818731816586 27 O75964,O75414,P17812,P00846,P56134 5 +Positive regulation of phospholipase activity 0.7281685306423831 1.4625289770282717 0.1435963097129269 1.0 0.3667774960211363 5 P40616 1 +Regulated exocytosis 0.4330779512304875 1.461286194915901 0.1439369168117028 1.0 0.36750095221035 32 O00186,Q4J6C6,P51809,O95295,Q00535,Q9UNH7,P07948,P04899,P09601,O00161,Q15907,P61026,Q13277,O43760,P49755,Q6WKZ4,P35080,P20339,P56545,Q9BRK5 20 +Mammalian oogenesis stage 0.5702238079792334 1.4590351677766986 0.144555428553545 1.0 0.3687861709733213 2 Q96MU7 1 +Negative regulation of phosphatase activity 0.72715277487321 1.4583236412375522 0.1447513568162621 1.0 0.3691390094605793 5 Q99653,O95429 2 +Guanine nucleotide transmembrane transport 0.6485107024311785 1.456354459977269 0.1452946577684455 1.0 0.3699334821192326 3 P41440 1 +Cyclic gmp amp transmembrane import across plasma membrane 0.6485107024311785 1.456354459977269 0.1452946577684455 1.0 0.3699334821192326 3 P41440 1 +Guanine nucleotide transport 0.6485107024311785 1.456354459977269 0.1452946577684455 1.0 0.3699334821192326 3 P41440 1 +Response to amphetamine 0.5689263704184159 1.452307082465773 0.1464162390585759 1.0 0.3716095195757676 2 P00492 1 +Regulation of actin nucleation 0.7270970629035465 1.4483929853148465 0.1475071754819406 1.0 0.373933900331346 4 Q7L576,P14373 2 +Regulation of dendrite development 0.4811491613226278 1.4461741875969372 0.1481283516596649 1.0 0.3753600556692301 20 Q9UQB8,Q86X55,Q96PU5 3 +Mitochondrion localization 0.5429505182018408 1.4441962674353297 0.1486837745577165 1.0 0.3761722985058183 14 P07196,Q9NVT9,O75153,Q9BUK6,O60313 5 +Detoxification of nitrogen compound 0.6452630483901107 1.4414655298692172 0.1494532088079501 1.0 0.3776715012322399 3 P28161 1 +Microtubule bundle formation 0.5648287960470035 1.4378144040579612 0.1504867213001501 1.0 0.3792360096966019 13 Q9UHD1,Q15555,A0AVF1,Q9NVR5,Q99653 5 +Pyrimidine containing compound transmembrane transport 0.6444184913161775 1.4375925384129482 0.1505496992718671 1.0 0.3792455263608261 3 Q9BSK2 1 +Positive regulation of response to dna damage stimulus 0.4102811599529458 1.4352920466487251 0.1512038932051349 1.0 0.3798478979890566 38 Q68CP9,P51114,Q9UBU8,Q9UNS1,Q13794,P18887,P23396,Q96T76,Q9NYF8,P35637,Q96B01 11 +Positive regulation of autophagy 0.4567717231601734 1.429163044359554 0.1529573767383647 1.0 0.3835003971098012 24 Q8TBX8,Q9Y371,P14373,P09601,O15269 5 +Positive regulation of response to reactive oxygen species 0.5643853389555556 1.428747279298158 0.1530768834545366 1.0 0.3835003971098012 2 Q13546 1 +Positive regulation of response to oxidative stress 0.5643853389555556 1.428747279298158 0.1530768834545366 1.0 0.3835003971098012 2 Q13546 1 +Negative regulation of calcium ion transport 0.6803418195964195 1.4274796769514728 0.1534416790348827 1.0 0.3842640327980682 8 P78417,P14373 2 +Regulation of sodium proton antiporter activity 0.6417732462451589 1.4254591440841586 0.1540245220534037 1.0 0.3855729145268091 3 Q99653 1 +Regulation of response to extracellular stimulus 0.7191224064163135 1.4250596819378765 0.1541399498809599 1.0 0.3857111402099333 5 Q9UMX5 1 +Regulation of muscle organ development 0.6795061750715621 1.423713373845741 0.1545294606889338 1.0 0.3864246298348437 8 P41440,Q9NQ29 2 +Neuron death 0.3646080902385696 1.4213407821570778 0.1552177129434797 1.0 0.3872701794107708 63 Q99720,P09601,Q15392,Q9UMX5 4 +Response to misfolded protein 0.6266060114460738 1.4163611025662788 0.15666980635247 1.0 0.3896677997923704 10 P46379,Q9Y679 2 +Regulation of osteoblast differentiation 0.6968531726887678 1.416193575255622 0.1567188364470579 1.0 0.3896677997923704 7 Q13418 1 +Response to cocaine 0.6774522679275555 1.414455315751323 0.1572282584407696 1.0 0.3904681926902383 8 Q05086,Q96KQ7,P80404,P50570 4 +Negative regulation of leukocyte migration 0.7165376204937712 1.414346947353195 0.1572600588730588 1.0 0.3904681926902383 5 P09601,O94813 2 +Negative regulation of transporter activity 0.6520020422520902 1.4137544789653296 0.1574340034056276 1.0 0.3907486345666217 9 Q96PU5,Q12955,P78417 3 +Regulation of long term synaptic depression 0.5604930262731054 1.4085403090565702 0.1589711397804554 1.0 0.3936486746940847 2 Q9NUL3 1 +Regulation of modification of synaptic structure 0.7163045127209355 1.4040863431562662 0.1602931398350855 1.0 0.3964624918083235 4 Q9UQB8 1 +Regulation of modification of postsynaptic structure 0.7163045127209355 1.4040863431562662 0.1602931398350855 1.0 0.3964624918083235 4 Q9UQB8 1 +Regulation of phosphatase activity 0.6025793800910981 1.4029781167067372 0.1606233646104358 1.0 0.3971259257794101 11 Q99653,O95429,P42345 3 +Negative regulation of nf kappab transcription factor activity 0.5219275992958842 1.4020660495091726 0.1608955240999525 1.0 0.3976453423550525 15 P42771,Q96RT1,Q9UHD1,Q96J02,P09525,Q9UN86,Q99653 7 +Histone h3 k9 modification 0.5581472878732813 1.4005934764579726 0.1613356728362087 1.0 0.3984257209671369 13 Q03164,Q15047 2 +Myotube differentiation 0.5354313103324487 1.4003532552546434 0.1614075605955638 1.0 0.3984496466956385 14 Q9BYT8,P41440,Q9H7B4,Q13547 4 +Coronary vasculature morphogenesis 0.6353999739162397 1.3962103425063144 0.1626511631319802 1.0 0.4007474427013329 3 Q68CP9 1 +Regulation of skeletal muscle tissue development 0.7090599272151104 1.3937001223995658 0.1634081792654897 1.0 0.4023031500287193 6 P41440 1 +Negative regulation of calcium ion transport into cytosol 0.7126712914792501 1.38916083734701 0.1647838474742795 1.0 0.405067278173536 4 P78417,P28161 2 +Dendrite extension 0.7094745460420704 1.3850620829312563 0.1660334847368958 1.0 0.4067515504125177 5 Q96F07 1 +Positive regulation of glycolytic process 0.5559519948102413 1.384952773401118 0.1660669085777586 1.0 0.4067515504125177 2 Q13131 1 +Negative regulation of tubulin deacetylation 0.5559519948102413 1.384952773401118 0.1660669085777586 1.0 0.4067515504125177 2 Q13131 1 +Polyadenylation dependent rna catabolic process 0.6896252796423995 1.3848315745677018 0.1661039737557206 1.0 0.4067515504125177 7 Q96B26,Q9NQT5 2 +Organelle transport along microtubule 0.4434126462846454 1.3801930738373205 0.1675272059763015 1.0 0.4093633865348609 26 O75381,Q8IXI1,P07196,Q8WXH0,Q9UH62,P62820,O60313,O94901 8 +Hepatocyte apoptotic process 0.5549789166396282 1.3798967560635238 0.1676184355489138 1.0 0.4093633865348609 2 Q13131 1 +Positive regulation of translation in response to stress 0.6317570572826419 1.3794836303661853 0.1677456899241352 1.0 0.4093633865348609 3 Q13217 1 +Positive regulation of translation in response to endoplasmic reticulum stress 0.6317570572826419 1.3794836303661853 0.1677456899241352 1.0 0.4093633865348609 3 Q13217 1 +Regulation of histone h3 k4 methylation 0.4890816526660034 1.378691797852247 0.1679897994757269 1.0 0.4096469948387919 17 Q6PD62,Q96KQ7,P38398,Q03164 4 +Stress granule assembly 0.5316041349237693 1.3780332656272178 0.1681930177179047 1.0 0.4096747039927367 14 P26196,P62266,Q14011,Q13131,Q9UN86,O00571,P05198 7 +In utero embryonic development 0.3494797591443856 1.3745220100066864 0.1692796820286228 1.0 0.4116953846147905 96 Q9H0G5,O43772,Q15293,Q9NR56,Q96MU7,Q6PD62,Q96AY3,Q14344,P62993,P31350,Q9BZK7,Q15648,P16989,Q6W2J9,Q6DKJ4,Q9HCK8,Q13895,Q9HCM4,P26572,P67809,P55199,P14635,Q9NQC3,Q9NVR5,Q9BRT9,Q14145,Q4VCS5,O14757,Q08J23,Q9NPQ8,O43819,Q16706,P24468,Q9Y5P4,P49321,P43246,Q12824 37 +Negative regulation of dna dependent dna replication 0.7080348304678712 1.3701083331533244 0.1706530869422107 1.0 0.4147206657632025 4 Q9UNS1 1 +Cellular aldehyde metabolic process 0.4697703624722149 1.3677500329375512 0.1713903329898629 1.0 0.4162655409022839 20 P48735,P49419 2 +Cerebral cortex cell migration 0.6167181993421711 1.3676592926366036 0.1714187475648181 1.0 0.4162655409022839 10 Q8WXH0,P61586,O94901,O94813 4 +Golgi vesicle transport 0.3146769564257648 1.3669616872860522 0.1716373146994176 1.0 0.4166383622449676 130 Q567U6,Q5JRA6,Q7Z3U7,P51809,Q6NUQ1,P49257,O60749,Q5BJH7,O43752,O14976,Q9Y3B3,Q92538,Q8WU17,O15126,P50570,O14653,Q96RL7,Q12955,O95782,Q9BZG1,Q9UHQ4,O75396,P60520,Q12907,Q9Y282,P98194,Q14746,P40616,P24390,O00471,Q96PC5,P83436,O43731,Q8N2H4,Q9UP83,O95249,P62820,O94979 38 +Isocitrate metabolic process 0.7023906226710019 1.365772446234366 0.1720103972941877 1.0 0.4173858352524874 6 P48735 1 +Regulation of ligase activity 0.6284879948085774 1.3644693607554486 0.1724198909229 1.0 0.4177436014827551 3 P18887,Q13155 2 +Negative regulation of ion transport 0.486745591229455 1.3635824122034017 0.1726990306148454 1.0 0.4180997606870894 17 Q96PU5,Q12955,P14373 3 +Intracellular receptor signaling pathway 0.3659794836818914 1.362619714690508 0.1730023922712407 1.0 0.4185246695202295 54 Q96RT1,Q9NUQ7,O75376,Q9NUD5,Q86X55,Q96J02,Q96HY6,P61586,Q05086,P42785,O43657 11 +Regulation of camp mediated signaling 0.6278390655418535 1.3614885363518685 0.1733593538375095 1.0 0.4188936831686364 3 P63096,P49427 2 +Mitochondrial respiratory chain complex assembly 0.3935260811770407 1.3611402931120613 0.1734693583496449 1.0 0.4188936831686364 42 O43676,P03886,O43819,O95168,Q96CU9,Q15070,Q9BSK2,O96000,O95831,Q9GZY4,Q9P0J0 11 +Exit from mitosis 0.5942643397562867 1.3603904251828105 0.1737064068072427 1.0 0.4190400310962236 11 Q9UJX2,O43264,P50748,Q96FF9,Q16763 5 +Protein peptidyl prolyl isomerization 0.4587390734283383 1.360109212161698 0.1737953663179143 1.0 0.4190400310962236 22 O95302,P26885,Q9NWM8 3 +Negative regulation of double strand break repair via nonhomologous end joining 0.5510866039571762 1.359668110532484 0.1739349738814952 1.0 0.4190400310962236 2 Q9UBB9 1 +Response to epidermal growth factor 0.5716470005254428 1.3540920375800185 0.1757070161864626 1.0 0.4217231718585537 12 Q9UQB8 1 +Viral protein processing 0.6823809050286792 1.3533873840567872 0.1759319057128641 1.0 0.4219451689833604 7 Q13724,Q16706,P61009 3 +Positive regulation of hematopoietic progenitor cell differentiation 0.5497891663963583 1.352923812759899 0.1760799710752576 1.0 0.4219858940172467 2 O43809 1 +Intrinsic apoptotic signaling pathway in response to dna damage 0.4521918538249615 1.3522597385573738 0.1762922392182375 1.0 0.4221787231521607 23 P23396,Q07812,Q07820,P46379,Q9HBM6,P09601,Q96K76 7 +Regulation of lamellipodium morphogenesis 0.5494648070061539 1.3512376427423614 0.1766193199219705 1.0 0.4225358950544551 2 Q92766 1 +Positive regulation of lamellipodium morphogenesis 0.5494648070061539 1.3512376427423614 0.1766193199219705 1.0 0.4225358950544551 2 Q92766 1 +Lymphocyte costimulation 0.6245944192083026 1.346582759281172 0.1781146498906214 1.0 0.4248696322044435 3 P07948,P41240 2 +Positive regulation of protein containing complex assembly 0.36785229674725 1.3428083634624084 0.1793340345727352 1.0 0.4273860957860647 51 Q16625,O95429,P62993,P63000,Q71SY5,P42345,P23396,Q14203,Q07812,Q9Y371,Q9UQB8,P36405,Q15691,P61586,Q9BPX3 15 +Ovarian follicle development 0.7012387493622427 1.3421728857356658 0.1795399458048596 1.0 0.4275647024589549 4 Q05086 1 +Cell cycle dna replication initiation 0.6967544414285077 1.3421651053538044 0.179542467938587 1.0 0.4275647024589549 6 Q9BRX5,P49736,P25205 3 +Nucleotide transmembrane transport 0.5906404502680184 1.3418292679174588 0.1796513600566027 1.0 0.4276650362402814 11 P41440,Q8TDW0,O43808,Q86VD7 4 +Positive regulation of protein serine threonine kinase activity 0.4560421631216066 1.3408628286324755 0.1799649927531694 1.0 0.4278169447290513 22 P30040,Q8NDZ4,P33121,P23396,P14635,Q9NQS7,Q9Y4R8,P61586,P41240,O00571,Q96A49 11 +Protein polymerization 0.3532622180011819 1.339317120600269 0.1804674575162128 1.0 0.427845630616682 67 Q16625,Q9NUQ9,Q14203,Q9UQB8,Q96CW5,O94813,Q9ULW0,Q7L576,Q9BPX3,P62993,P63000,P23396,P35611,P61586,O15145,Q15691,Q96P70,Q96F07,Q16763,O95429,Q9UEY8,P42345,P07196 23 +Adrenergic receptor signaling pathway 0.6229720960415326 1.339128995998773 0.1805286824159846 1.0 0.427845630616682 3 P04899,Q9Y4G8 2 +Adenylate cyclase activating adrenergic receptor signaling pathway 0.6229720960415326 1.339128995998773 0.1805286824159846 1.0 0.427845630616682 3 P04899,Q9Y4G8 2 +Response to acetylcholine 0.6229720960415299 1.3391289959987605 0.1805286824159888 1.0 0.427845630616682 3 P04899,P46109 2 +Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway 0.6229720960415298 1.3391289959987605 0.1805286824159888 1.0 0.427845630616682 3 P04899,P17252 2 +Regulation of presynaptic cytosolic calcium ion concentration 0.6229720960415227 1.3391289959987285 0.1805286824159993 1.0 0.427845630616682 3 Q00535,P20020 2 +Muscle cell differentiation 0.3630737519514798 1.336556508178132 0.1813674435676153 1.0 0.4291983167691703 55 P11310,P41440 2 +Cellular modified amino acid metabolic process 0.361814622950469 1.3355439720227291 0.1816983736316793 1.0 0.4295054544223385 57 P11310,P49419,O75874,P50416,P41440,O60725,P78417 7 +Regulation of mrna catabolic process 0.351662530247722 1.334558325837752 0.182020945302076 1.0 0.4298433704626097 68 Q92804,Q14011,Q5JVF3,Q7L8L6,Q969T7,P62487,P16989,Q13868,Q92945,Q53R41,Q6P6C2,Q9NQT5,P67809,Q99729,Q15024,Q96C86,P98175,P51114,Q96B26,Q9HCE1,O00178,O15514,O95453,P35637 24 +Biological process involved in intraspecies interaction between organisms 0.697784941397902 1.3279734499323643 0.1841868780528777 1.0 0.4336141508298213 4 Q96RL7 1 +Cation transport 0.3120048849554015 1.3277860845257534 0.1842487852886003 1.0 0.4336141508298213 157 P13073,Q9HD20,P61619,Q96ES6,O43772,P51809,Q70HW3,O43808,Q9Y619,Q8WWI5,P00846,Q15758,P30825,Q9NUT2,Q9UM00,Q12955,Q9HC07,P08574,P14373,O00400,P61586,P78417,P98194,Q13586,Q07812,Q13423,O43865,Q86VD7,Q9UJZ1,Q96PU5,Q96NB2,O75964,P54652,Q13555,P56134,Q99653 36 +Response to alkaloid 0.4639131257225258 1.3274024058624383 0.1843756042793458 1.0 0.4337532578088466 20 P50570,P28161,P50416,P80404,Q00535,Q13242,Q13131,Q96KQ7,O14757,Q05086 10 +Protein quality control for misfolded or incompletely synthesized proteins 0.5665662889562189 1.3269821546471472 0.1845145858921906 1.0 0.4339208653543954 12 P46379,Q9NYU2,Q9Y679 3 +Response to mineralocorticoid 0.6929896085490957 1.326394572088646 0.1847090357662248 1.0 0.4342187460985088 6 O95831 1 +Osteoblast proliferation 0.6194306857697132 1.3228565386769071 0.1858830908609061 1.0 0.4361784176025512 3 P61586 1 +Regulation of osteoblast proliferation 0.6194306857697132 1.3228565386769071 0.1858830908609061 1.0 0.4361784176025512 3 P61586 1 +Double strand break repair via break induced replication 0.6750264720102114 1.3214617227733585 0.1863474573284707 1.0 0.4369479544824975 7 P25205 1 +Positive regulation of er associated ubiquitin dependent protein catabolic process 0.5436263379824754 1.3208814847045882 0.1865408842814608 1.0 0.4371245494440271 2 P51572 1 +Nucleus localization 0.5654124698102687 1.320826432193006 0.186559244174207 1.0 0.4371245494440271 12 Q8WXH0,O94901,Q96N67,Q9Y613 4 +Regulation of histone h2b ubiquitination 0.6953924517633594 1.3181368508755582 0.18745784039049 1.0 0.4380376188102997 4 P50750 1 +Positive regulation by host of viral transcription 0.6734999360067887 1.3148352476311242 0.1885652785722333 1.0 0.4395739354198424 7 Q12824 1 +Negative regulation of immune response 0.4738920697961841 1.3143540560671931 0.1887270840012083 1.0 0.4396912454136685 18 P09601,P14373 2 +Antigen processing and presentation of endogenous peptide antigen 0.6894063604180611 1.31138463987712 0.1897278456063635 1.0 0.4411602827420563 6 Q03519,Q9NZ08,Q03518 3 +Antigen processing and presentation of endogenous antigen 0.6894063604180611 1.31138463987712 0.1897278456063635 1.0 0.4411602827420563 6 Q03519,Q9NZ08,Q03518 3 +Negative regulation of blood pressure 0.6933521560222465 1.3097481574297845 0.1902810463549249 1.0 0.441965331018727 4 Q9HB40,P42785 2 +Endoplasmic reticulum to golgi vesicle mediated transport 0.3517449596378595 1.30842565790573 0.1907289746828482 1.0 0.4426847144269296 66 Q5JRA6,P51809,Q6NUQ1,P49257,Q5BJH7,Q9Y3B3,Q92538,Q8WU17,O14653,Q9UHQ4,O75396,Q12907,Q9Y282,P24390,Q96PC5,O43731,O95249,P62820,O94979 19 +Dephosphorylation 0.3492828394472758 1.3064345267000612 0.1914048308228064 1.0 0.4437710265113638 68 O95429,P78318,P49902,Q9UHD1,P30154,Q99956,P42345,Q99653,Q8TF05,Q9H0C8,Q9NPH0,Q9C0I1,Q13555,Q10713,Q13614,Q9NY27,Q969T7,Q5TFE4 18 +Apoptotic process involved in development 0.6703617045440771 1.301213477506844 0.1931853932855687 1.0 0.4467191741057275 7 O94813,O14757,Q07812,P30154 4 +Granulocyte differentiation 0.6701114436770471 1.300127261631952 0.1935573554857859 1.0 0.4471224329672449 7 Q96JM7 1 +Positive regulation of pattern recognition receptor signaling pathway 0.6700705988788505 1.299949982578634 0.1936181125587164 1.0 0.4471224329672449 7 Q9NUD5,P41440 2 +Response to temperature stimulus 0.3844585712204515 1.298426959929264 0.1941406599058486 1.0 0.4472082818875023 43 P11310,P42345,Q9UHD1,P54652,Q14011,Q13217,O15514,P09601 8 +Dna synthesis involved in dna repair 0.5821627094688093 1.2984173400183314 0.1941439637728916 1.0 0.4472082818875023 11 P40938,Q96S55,P49005 3 +Phosphatidylglycerol biosynthetic process 0.6901185673086979 1.2964533774836746 0.1948193325747584 1.0 0.4483535540631394 4 Q96BW9 1 +Regulation of embryonic development 0.4762334441698461 1.2956259529546452 0.195104383303307 1.0 0.4483535540631394 17 P46379,Q4VCS5 2 +Androgen receptor signaling pathway 0.5035517818429517 1.2913585463780668 0.1965793779224431 1.0 0.4511958061523364 15 O75376,P61586,Q05086 3 +Apoptotic process involved in morphogenesis 0.6886223849386547 1.290302081620332 0.1969457944381876 1.0 0.4514001613175359 4 P30154 1 +Negative regulation of response to cytokine stimulus 0.6876661173653607 1.2863706593905688 0.1983137331562117 1.0 0.453066253423214 4 O94813 1 +Rrna catabolic process 0.5369492947470217 1.2825098361420002 0.199663856715218 1.0 0.4546388113227269 13 Q13868,Q96B26,Q9NQT5 3 +Polysaccharide metabolic process 0.4741621370196457 1.2822470377126152 0.1997560003614618 1.0 0.4546388113227269 17 P11310,P31751,Q7LGA3 3 +Ncrna catabolic process 0.4473839819927257 1.2791385375093152 0.2008482749026932 1.0 0.4562532088746995 22 Q13868,Q96B26,Q9NQT5,Q99575 4 +Response to caffeine 0.6853887039465284 1.2770081640098283 0.2015993650022818 1.0 0.4576014377857785 4 O14757,P28161 2 +Reelin mediated signaling pathway 0.6089312693332103 1.2746100935275375 0.202447283108696 1.0 0.458909163338396 3 P46109 1 +Nucleoside triphosphate metabolic process 0.381794670579065 1.273097571249027 0.2029834207024849 1.0 0.4595986986318535 43 O75964,O75414,P17812,P56134,Q9H773,O60313,P00846,Q9UJZ1,P61586 9 +Dna strand elongation involved in dna replication 0.5563309921495435 1.2723965197777602 0.2032322699916806 1.0 0.4597125429260968 12 P25205 1 +Ion transmembrane transport 0.3075354947096606 1.271945119002963 0.2033926193519537 1.0 0.4599128554778029 162 P13073,Q9HD20,P61619,Q96ES6,O43772,Q70HW3,O43808,Q9Y619,O60831,P00846,Q15758,P41440,P30825,Q6P4A7,Q9NUT2,Q9UM00,Q12955,Q9UHG3,Q9HC07,Q8TDW0,P08574,O00400,P78417,P98194,Q9BQT8,Q8TB61,Q13586,Q07812,Q13423,O43865,Q86VD7,Q9C0H2,Q9UJZ1,Q96PU5,Q96NB2,O75964,P54652,P56134,Q99653 39 +Synaptic vesicle localization 0.5559276390742244 1.2702466296981163 0.2039967925153587 1.0 0.460304139786329 12 Q96A57,O00203,P50570,O95295,Q9Y2T2,Q13492,Q00535 7 +Synaptic vesicle membrane organization 0.6792518789251943 1.2688556738026346 0.2044925441762128 1.0 0.4612028231640898 6 Q13277,O43760,O95295 3 +Cellular response to nutrient 0.6628678824774995 1.268693911527376 0.2045502548261963 1.0 0.4612028231640898 7 O15164,Q15648,Q8TB36,Q96C86,P09601 5 +Positive regulation of rna binding 0.6791725537525408 1.268523523024902 0.2046110557964944 1.0 0.4612028231640898 6 O15371,P50750 2 +Regulation of mrna binding 0.6626721626004018 1.2678447928632637 0.2048533824861003 1.0 0.4615866226542239 7 Q86X55,O15371,P50750 3 +Positive regulation of translational initiation 0.6447563735921322 1.2670279148360573 0.2051453086768453 1.0 0.4616867846904713 8 Q13217,P42345,O15514 3 +Vesicle cargo loading 0.5340768508396829 1.2665242595144377 0.205325449694335 1.0 0.4616867846904713 13 Q5JRA6,P62820,Q15436,P49755,Q13492,Q96PC5,O95487,O94979 8 +Nuclear migration 0.5748943479258588 1.2612222907648143 0.2072287697006161 1.0 0.4649763568133614 11 Q8WXH0,O94901,Q96N67 3 +Polysaccharide biosynthetic process 0.5329422687425003 1.2602120311038485 0.2075928838658964 1.0 0.4649790258898366 13 P11310,P31751,Q7LGA3 3 +Ribonucleoside monophosphate catabolic process 0.6056151470502003 1.2593744827073947 0.2078951017380625 1.0 0.465020207455763 3 P49902 1 +Purine nucleoside monophosphate catabolic process 0.6056151470502003 1.2593744827073947 0.2078951017380625 1.0 0.465020207455763 3 P49902 1 +U4 snrna 3 end processing 0.6605620979572994 1.258691268078354 0.2081418665791736 1.0 0.465020207455763 7 Q96B26,Q9NQT5 2 +Peptidyl lysine acetylation 0.3651386737709342 1.2584174061592954 0.2082408401817328 1.0 0.465020207455763 49 Q9UBU8,Q03164,P46379,Q86UY6,Q12824,Q9UKN8,Q9P265 7 +Development of secondary sexual characteristics 0.6808082022472206 1.2581802746610324 0.2083265669816973 1.0 0.465020207455763 4 Q07812 1 +Negative regulation of macroautophagy 0.5740788043908496 1.25705088076491 0.2087352118966285 1.0 0.4653856239594011 11 P42345,Q96KQ7,O75396,Q9NRR5,P09601 5 +Circadian regulation of gene expression 0.4841053221439726 1.255710906763731 0.209220803382403 1.0 0.465694394186127 16 Q03164,P43490,Q9Y2K7 3 +Regulation of dendrite morphogenesis 0.510392804761716 1.2544068769966985 0.2096941542222188 1.0 0.4661957597463945 14 Q9UQB8 1 +Mitochondrial protein processing 0.6756071874948506 1.2535964607620176 0.2099887182984916 1.0 0.4661957597463945 6 Q10713 1 +Negative regulation of necrotic cell death 0.6796664208283862 1.2534877651907683 0.2100282489272704 1.0 0.4661957597463945 4 P16989 1 +Negative regulation of programmed necrotic cell death 0.6796664208283862 1.2534877651907683 0.2100282489272704 1.0 0.4661957597463945 4 P16989 1 +Regulation of lymphocyte migration 0.6776200996826452 1.252910084513865 0.2102384314137417 1.0 0.4663391245278496 5 P61586 1 +Liver regeneration 0.5930622908831952 1.2511801276083676 0.2108687667902435 1.0 0.4673943622165466 10 P50416,P09601 2 +Podosome assembly 0.67824912839845 1.2476634389864698 0.2121543357037341 1.0 0.4689650360656041 4 P61586 1 +Regulation of podosome assembly 0.67824912839845 1.2476634389864698 0.2121543357037341 1.0 0.4689650360656041 4 P61586 1 +Positive regulation of podosome assembly 0.67824912839845 1.2476634389864698 0.2121543357037341 1.0 0.4689650360656041 4 P61586 1 +Regulation of meiotic nuclear division 0.6028552887735329 1.2466966926888683 0.2125087319799616 1.0 0.4692626463507874 3 P27797,Q96B01 2 +Regulation of meiotic cell cycle 0.6028552887735329 1.2466966926888683 0.2125087319799616 1.0 0.4692626463507874 3 P27797,Q96B01 2 +Nadh dehydrogenase complex assembly 0.4094824802633361 1.2435443565938842 0.2136673061788365 1.0 0.4711713471193208 31 O43676,P03886,Q15070,O95168,Q96CU9,O96000,Q9GZY4,Q9P0J0 8 +Pyrimidine ribonucleoside triphosphate biosynthetic process 0.6751852942654053 1.2428138650787128 0.2139364320316992 1.0 0.4714402420347661 5 O75414 1 +Nuclear transcribed mrna catabolic process exonucleolytic 3 5 0.6153452360002841 1.241253220836398 0.2145122197408995 1.0 0.4718911458413837 9 Q13868,Q96B26,Q9NQT5 3 +Positive regulation of g protein coupled receptor signaling pathway 0.6016283791679873 1.2410614943205285 0.2145830327561584 1.0 0.4718911458413837 3 O14744 1 +Positive regulation of collagen metabolic process 0.5264352903016476 1.2314967006206188 0.2181371499077489 1.0 0.4775757287454137 2 Q92769 1 +Cellular response to muramyl dipeptide 0.5264352903016458 1.2314967006206106 0.218137149907752 1.0 0.4775757287454137 2 Q92974 1 +Lens fiber cell differentiation 0.5264352903016442 1.2314967006206017 0.2181371499077553 1.0 0.4775757287454137 2 P28289 1 +Lens fiber cell development 0.5264352903016442 1.2314967006206017 0.2181371499077553 1.0 0.4775757287454137 2 P28289 1 +Regulation of calcium ion transport into cytosol 0.5890020669744679 1.2312147420667487 0.2182425591459114 1.0 0.4776432640549055 10 P28161,Q07812,P55061,P17252,P78417 5 +Positive regulation of double strand break repair via homologous recombination 0.4799575569702303 1.2299095753492268 0.2187309681290798 1.0 0.4782220415818722 16 Q68CP9,Q9UBU8,Q9UNS1,Q96T76,Q96B01 5 +Cellular response to arsenic containing substance 0.6536369435847347 1.2286630624891366 0.2191981606734976 1.0 0.4789165816079214 7 P09601 1 +Myelin assembly 0.6734578545234604 1.2279785084345438 0.2194550358551357 1.0 0.4791509746721197 4 Q9Y2J2,Q13614 2 +Negative regulation of calcium ion transmembrane transport 0.669353994534132 1.2274272186800337 0.2196620613676168 1.0 0.4792637742726031 6 P78417 1 +Sensory system development 0.401830719774583 1.2254094963390152 0.2204209707195357 1.0 0.4802778021868523 33 Q15293,Q15555,O43819,Q13547,Q16706,Q9NP72 6 +Regulation of smooth muscle contraction 0.6726653878805096 1.224723464092916 0.2206794303076027 1.0 0.4806774670351931 4 P80404,P61586 2 +Tetrapyrrole catabolic process 0.6724216868099699 1.223722516586996 0.22105692255789 1.0 0.481172492662536 4 P09601 1 +Positive regulation of oligodendrocyte differentiation 0.6717237700537423 1.2208561162617366 0.2221405024022509 1.0 0.4828748077328874 4 Q13547,P42345 2 +Regulation of response to dna damage stimulus 0.3414660963058783 1.2206362339437815 0.2222237809112914 1.0 0.4828919743954318 71 Q07820,Q96B01,Q9NY27,O95071,Q9UNS1,P18887,P38398,P23396,P50750,Q9HBM6,Q9NRR5,Q96K76,Q68CP9,Q9NYF8,O14757,P51114,Q9UBU8,Q13794,Q96T76,P35637,Q96S55,O96028 22 +Cation transmembrane transport 0.3119303290821051 1.2163642334275009 0.2238462024801237 1.0 0.4857583919673688 121 P13073,Q9HD20,P61619,Q96ES6,O43772,Q70HW3,Q9Y619,P00846,Q15758,P30825,Q9NUT2,Q9UM00,Q12955,Q9HC07,P08574,O00400,P78417,P98194,Q13586,Q07812,Q13423,Q9UJZ1,Q96PU5,Q96NB2,O75964,P54652,P56134,Q99653 28 +Regulation of peptidyl serine phosphorylation 0.4473807308620597 1.2137672514925992 0.2248366151132939 1.0 0.4874123033555874 20 O95429,Q9H7B4 2 +External encapsulating structure organization 0.4428998777483116 1.2134125298649976 0.2249721381681959 1.0 0.4875411086283705 21 Q96AY3,P41440,Q53GQ0 3 +Ion transport 0.2897730776924271 1.212385086058006 0.2253650071453106 1.0 0.4880622838988708 214 P13073,Q9HD20,P61619,Q96ES6,O43772,P51809,Q70HW3,O43808,Q9Y619,Q8WWI5,O60831,P00846,Q15758,P41440,Q8NE01,P30825,Q6P4A7,Q9NUT2,Q9UM00,Q12955,Q9UHG3,Q9HC07,Q8TDW0,P08574,P14373,Q08722,O00400,P61586,P78417,P98194,Q9BQT8,Q8TB61,Q13586,Q07812,Q13423,Q6N075,O43865,Q86VD7,Q9C0H2,Q9UJZ1,Q96PU5,Q96NB2,O75964,P54652,P10620,Q13555,Q9UHQ9,Q9Y5P4,P56134,Q99653,O96008 51 +Positive regulation of fat cell differentiation 0.6695929280869297 1.2121058918401275 0.2254718486794338 1.0 0.488128645704783 4 Q86X55 1 +Inner mitochondrial membrane organization 0.4328195780977671 1.2117177555925405 0.2256204400334449 1.0 0.4882853171804893 23 Q13505,Q9BUR5,P62072,Q9H3K2,Q9P0J0 5 +Protein acylation 0.3490567888762069 1.2103131574218178 0.2261587507907072 1.0 0.4892850245070147 59 Q9UBU8,Q03164,P46379,Q86UY6,Q12824,Q02218,Q9UKN8,Q9P265 8 +Single stranded viral rna replication via double stranded dna intermediate 0.6319080170927605 1.2091739054424773 0.2265960405910787 1.0 0.4897043032540235 8 Q15047 1 +Skeletal muscle cell differentiation 0.6488790921688936 1.2080474371457013 0.2270290162063688 1.0 0.4901745459447248 7 Q9BYT8,Q9Y5Q8,Q8NC56,P50402 4 +Protein autoubiquitination 0.6316039098027842 1.2078058840541237 0.2271219376579492 1.0 0.4902099503493337 8 Q96T88,Q05086 2 +Inositol phosphate metabolic process 0.6663372560304599 1.206144264395541 0.227761869957376 1.0 0.4912601141235524 5 Q10713,Q13614 2 +Actin filament polymerization 0.386302040550342 1.2049712511111257 0.2282144004253714 1.0 0.4919049290460731 37 O95429,Q9UEY8,Q9UQB8,P35611,Q96F07,O94813,P61586 7 +Regulation of synaptic vesicle recycling 0.6673158065563158 1.202757348570791 0.2290702342314137 1.0 0.493251737978634 4 Q96CW1,Q7L576,Q00535 3 +Roof of mouth development 0.6653211617374416 1.2019356258056002 0.2293884702142015 1.0 0.4936051529029811 5 Q92688,Q9NWT1,Q6W2J9 3 +Regulation of ryanodine sensitive calcium release channel activity 0.6669722945239557 1.2013473151968028 0.2296165037252924 1.0 0.4937641231501253 4 P78417,P28161 2 +Release of sequestered calcium ion into cytosol by endoplasmic reticulum 0.6669722945239557 1.2013473151968028 0.2296165037252924 1.0 0.4937641231501253 4 P78417,P28161 2 +Mitotic cytokinesis 0.406642257607333 1.201075495068715 0.2297219176544487 1.0 0.4938250350652344 30 Q6DKK2,Q14141,Q13432,Q12955,P61586 5 +Trna modification 0.4409684336695519 1.199947583654831 0.2301596981302158 1.0 0.4946001429795917 21 Q9NNW5,Q969Y2,O95163,O75648,Q7Z2T5,Q5JTZ9,Q5VV42,Q9NX74,Q7L0Y3,Q08J23,Q9H974 11 +Positive regulation of endothelial cell proliferation 0.6297438785217765 1.1994401827625372 0.2303568308785248 1.0 0.4946918734856957 8 P09601 1 +Regulation of mammary gland epithelial cell proliferation 0.6660947875327514 1.1977456477027693 0.2310160525757523 1.0 0.495325288151625 4 Q9NQC3,Q07812 2 +Regulation of exit from mitosis 0.6621948905606674 1.1974897573090555 0.2311157174969103 1.0 0.495325288151625 6 P50748,Q9UJX2,Q96FF9 3 +Response to purine containing compound 0.4878254403100805 1.1968324766419562 0.231371857045437 1.0 0.4955426667445903 15 P30520,P21953,Q86X55,P28161 4 +5 phosphoribose 1 diphosphate metabolic process 0.5914942387281583 1.1945414514648738 0.2322662361640097 1.0 0.4969597558004832 3 Q14558 1 +Neuromuscular junction development 0.6610460303986114 1.1926883384685811 0.2329914544212352 1.0 0.4980124314389166 6 P46109,Q14203,Q12955 3 +Regulation of myeloid leukocyte mediated immunity 0.6280690790720571 1.191910072802388 0.2332965081433753 1.0 0.4983319210291638 8 P09601 1 +Dna dependent dna replication 0.3401780076243514 1.1907630805800784 0.2337466062560049 1.0 0.4991269198919892 78 Q96RR1,P49736,Q9Y619,P25205,P46063,Q9BRX5,P41440,Q9UBD5,Q9UNS1,Q86V81,O75717,Q9BTE3,P78362,P50750,Q7Z7L1,P49427,Q96FV9,Q9BQP7,Q9BRT9,Q13416,Q9UJZ1,P40938,P49005,Q9NR33,P24941,P49959,Q96S55 27 +Oocyte maturation 0.5905256327060373 1.1900982250523395 0.2340077878299316 1.0 0.4993517284605402 3 P30153,Q15645 2 +Energy derivation by oxidation of organic compounds 0.3056034730075054 1.1884836255993654 0.234642927182703 1.0 0.5005379082721128 124 P13073,P11310,P03886,Q9BSK2,P00846,Q16718,Q02218,O43676,P48735,P08574,P61586,Q9P2R7,P14635,O95168,Q13423,O75964,O75874,O43819,O96000,P56134,Q15070 21 +3 phosphoadenosine 5 phosphosulfate metabolic process 0.5901309884438646 1.188288083890197 0.2347199307601353 1.0 0.5005379082721128 3 O43252 1 +Homologous chromosome pairing at meiosis 0.6030008491484771 1.1832944531931442 0.236692470346794 1.0 0.5037381943659677 9 P46379,Q9BXW9,Q96KQ7,O94901 4 +Negative regulation of histone h3 k9 methylation 0.6624165245861351 1.1826532362821451 0.2369466046525024 1.0 0.5039442063094058 4 P38398,Q12824 2 +Regulation of receptor mediated endocytosis 0.4383841451204355 1.1819489690310712 0.2372259499407805 1.0 0.5042035286398938 21 Q9Y5K6,P50570,Q13432,Q96CW1,Q13492,Q13614,P41440 7 +Negative regulation of establishment of protein localization to mitochondrion 0.662176493342789 1.181668640062458 0.2373372062270045 1.0 0.5042454222911209 4 P49257,O95429 2 +Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.5886514265749752 1.181502678915606 0.2374030898579489 1.0 0.5042454222911209 3 P63241 1 +Retrograde axonal transport 0.6254461953576577 1.1801223437891015 0.2379515590876457 1.0 0.5052428530047924 8 Q03001,O95295,P07196 3 +Lipid droplet organization 0.6420469693457098 1.1784715011251028 0.2386086873462776 1.0 0.5052617354833345 7 Q9Y679,Q9NP72 2 +Negative regulation of i kappab kinase nf kappab signaling 0.6576400754259977 1.1784591448039752 0.2386136106813099 1.0 0.5052617354833345 6 P61586 1 +Growth plate cartilage development 0.5879299156391975 1.178194358892278 0.2387191309759335 1.0 0.5052617354833345 3 O75844,P16435 2 +Bone growth 0.5879299156391975 1.178194358892278 0.2387191309759335 1.0 0.5052617354833345 3 O75844,P16435 2 +Negative regulation of dephosphorylation 0.6248809988795283 1.177583102941506 0.2389628493851665 1.0 0.5053799977422835 8 Q99653,O95429 2 +Muscle cell proliferation 0.4167300103351269 1.1772997592615149 0.2390758829789416 1.0 0.5054521803178549 26 Q14344,Q8NDZ4,Q13547,P09601,P61586 5 +Tetrahydrobiopterin metabolic process 0.5869592670605872 1.1737443191068124 0.2404974526803722 1.0 0.5076306372007644 3 P00374 1 +Regulation of nuclear transcribed mrna poly a tail shortening 0.5869565217391405 1.1737317339640192 0.2405024951458507 1.0 0.5076306372007644 3 P11940,P62487 2 +Regulation of small gtpase mediated signal transduction 0.3981341582595012 1.1718502742684802 0.2412571741670857 1.0 0.5084198506774598 32 Q9Y5K6,Q14344,Q9NUQ9,Q96RT1,Q15555,O94813,Q4VCS5,P41440,Q92538 9 +Positive regulation of toll like receptor signaling pathway 0.6578961746845176 1.17120082069405 0.2415180654954816 1.0 0.5087684076172493 5 P41440 1 +Regulation of protein targeting 0.4218057178256443 1.1704753307377556 0.2418097360665454 1.0 0.5090480345850443 24 O95429,P31751,Q9UHD1,P55786,P49257,Q12955,Q99653,Q9Y371,Q9P275,Q86YS7 10 +Trna wobble uridine modification 0.6588769879909151 1.1681380879321062 0.242751068982115 1.0 0.5106940387190243 4 O75648,O95163,Q969Y2 3 +Regulation of rna binding 0.5996833978356186 1.1677436608903464 0.2429101796351696 1.0 0.51086100155709 9 Q86X55,O15371,P50750 3 +Regulation of ire1 mediated unfolded protein response 0.6393461437597094 1.166790306088845 0.243295062749735 1.0 0.511502517878176 7 Q96HY6 1 +Regulation of protein modification process 0.2599828416413116 1.1653775935055426 0.2438661829760349 1.0 0.5124572268172585 270 O15031,Q16625,Q8NDZ4,Q9UHD1,Q03164,P49736,Q14166,Q13432,O43823,O00410,Q96HY6,Q96KQ7,Q96M27,O94813,Q96KB5,P41440,Q9BRG1,Q9ULW0,Q9NY27,Q00535,Q13418,Q9P265,Q6PD62,Q9H7B4,O95071,P63000,P31751,P23396,P38398,P18887,Q96ES7,Q92797,Q32P28,Q6W2J9,Q6DKJ4,P14373,P50750,P61586,Q96A49,Q05086,Q9H2J4,P14635,O60566,Q13217,Q96N67,Q96J02,Q07812,Q9NQS7,P62841,Q16763,O14757,O95373,Q9BX68,P42771,O95429,P61981,Q8IXB1,P51114,Q9NVI1,P33121,Q9HAW4,Q9BZF1,P54652,Q99653,P42345,P49959,P54619,P24468,Q96DY7,O95816,Q12824 71 +Regulation of release of sequestered calcium ion into cytosol 0.621272653352944 1.1613796960271878 0.2454875222819041 1.0 0.5143010662938917 8 Q07812,P78417 2 +Nucleotide excision repair dna gap filling 0.5128121959130622 1.160759354276354 0.2457397766483353 1.0 0.5143010662938917 2 Q07864 1 +Error free translesion synthesis 0.5128121959130608 1.1607593542763477 0.245739776648338 1.0 0.5143010662938917 2 Q9Y2S7 1 +Estrogen biosynthetic process 0.6570188110964911 1.1605214742668024 0.2458365558340491 1.0 0.5143010662938917 4 Q53GQ0 1 +Dna templated transcription initiation 0.3721085983291928 1.1603391897019648 0.2459107346328739 1.0 0.5143010662938917 42 P17480,P62487,P35269,Q15648,Q9Y2X0,Q6P2C8,O15514,O15160,Q9NYF8,Q9Y5Q8,P50750,Q9HBM6,Q12824,O60244,P11802,Q9UKN8 16 +Homologous chromosome segregation 0.5548022535247704 1.1586443716523978 0.246601174416762 1.0 0.5153858958008213 11 Q9BXW9,P53350,O60216,Q96KQ7,Q03188,P46379,P49959,O94901 8 +Amine metabolic process 0.4501200220756211 1.1580530110574234 0.2468424039214811 1.0 0.5153858958008213 18 P49419 1 +Negative regulation of protein localization to cell periphery 0.6527331335636134 1.157974665446585 0.2468743752836522 1.0 0.5153858958008213 6 Q96CW1,Q13492,P41240 3 +Negative regulation of protein localization to membrane 0.6527331335636134 1.157974665446585 0.2468743752836522 1.0 0.5153858958008213 6 Q96CW1,Q13492,P41240 3 +Regulation of dna methylation dependent heterochromatin assembly 0.6202599458223959 1.1568346151244595 0.2473399365013837 1.0 0.5157547238689237 8 Q15047 1 +Proteasome assembly 0.6560286759786613 1.1564639974354527 0.2474914176042884 1.0 0.5157547238689237 4 O95456 1 +Centrosome separation 0.6540821765295065 1.1554285272404994 0.247914985439495 1.0 0.5161357699305826 5 P52732 1 +Negative regulation of intracellular steroid hormone receptor signaling pathway 0.57354423363148 1.1553513577598846 0.2479465725688228 1.0 0.5161357699305826 10 O75376,Q13547,P61586 3 +Dna strand elongation 0.4388118148552584 1.1551183354568797 0.2480419707051337 1.0 0.5161357699305826 20 P25205 1 +Histamine production involved in inflammatory response 0.6556312885426842 1.1548357567275709 0.2481576914433647 1.0 0.5161357699305826 4 Q9UNH7,O00161,P51809 3 +Histamine transport 0.6556312885426842 1.1548357567275709 0.2481576914433647 1.0 0.5161357699305826 4 Q9UNH7,O00161,P51809 3 +Histamine secretion 0.6556312885426842 1.1548357567275709 0.2481576914433647 1.0 0.5161357699305826 4 Q9UNH7,O00161,P51809 3 +Purine containing compound transmembrane transport 0.5732332858521952 1.153828329833949 0.2485705570603329 1.0 0.5168266759261579 10 Q86VD7,Q8TB61,O43808,Q8TDW0,P41440 5 +Positive regulation of inclusion body assembly 0.5825334272091574 1.1534637349263392 0.2487200943753198 1.0 0.5169698003141787 3 P49427 1 +Actin polymerization or depolymerization 0.3662226151423143 1.1481871756793116 0.250891302249923 1.0 0.521144514336254 44 O95429,Q9NUQ9,Q9UEY8,P63000,P42345,Q9UHB6,Q9UQB8,P35611,Q96F07,O94813,P61586,Q7L576,O15145 13 +Cellular response to exogenous dsrna 0.6349022678684029 1.147585395527537 0.251139761630077 1.0 0.5214915115080302 7 P41440 1 +Regulation of superoxide metabolic process 0.6530347289840993 1.144199853232599 0.2525407639768149 1.0 0.5233827674006717 4 P08754,Q9NY61,P00374 3 +Modification of postsynaptic structure 0.6338340630290911 1.142972002675256 0.2530502154910499 1.0 0.5242689781486628 7 Q9UQB8,P61586,O95793 3 +Positive regulation of response to endoplasmic reticulum stress 0.6165178994559092 1.1400505037327635 0.2542652610893712 1.0 0.5264457862115424 8 P46379,Q13794 2 +Tricarboxylic acid metabolic process 0.5934625097363134 1.1386190840727737 0.2548620651103985 1.0 0.5273405649538803 9 P48735 1 +Cellular response to ketone 0.4516578298560058 1.1373762924759103 0.2553810136436991 1.0 0.5279027987742939 17 O43823,O95831,Q9H7B4 3 +Positive regulation of nf kappab transcription factor activity 0.4268694623060035 1.1336121369605858 0.2569572797080144 1.0 0.5300970310859088 22 P41440,P14373 2 +Immune response regulating signaling pathway 0.3595699495767057 1.13326137340898 0.2571045075841272 1.0 0.5300970310859088 46 Q96RT1,P23396,Q9NUD5,Q07812,Q96J02,Q9NPR9,Q9NQC3,P51812,Q08722,P46379,P41440,Q9UJZ1,O43657 13 +Regulation of lipid storage 0.6149471691217039 1.1330105001777129 0.2572098438620309 1.0 0.5301202531665178 8 Q9BZF1,P50416 2 +Positive regulation of smoothened signaling pathway 0.6485223958810378 1.1324589227635988 0.257441544662595 1.0 0.5301202531665178 5 Q96J42 1 +Response to cold 0.5094924308790273 1.130127936307828 0.2584223197135258 1.0 0.5317871442611135 13 P54652,Q14011,P11310 3 +Regulation of histone phosphorylation 0.645866059553754 1.1293432296180193 0.2587530712389971 1.0 0.5321301467784354 6 O43823,P50750 2 +Organic acid transmembrane transport 0.3873881146230752 1.1289106095520678 0.2589355447005346 1.0 0.5321594800614773 34 P30825,Q96NB2,P33121,O43772,Q9BQT8,P50416,Q9Y619,O60831,Q8TDW0,Q15758,P41440 11 +Regulation of actin cytoskeleton reorganization 0.5906068002011026 1.125267231041425 0.2604758112618053 1.0 0.5333135745976659 9 Q13576,Q9UQB8 2 +Synaptonemal complex organization 0.6296752026498929 1.125022790351834 0.2605793769108171 1.0 0.5333135745976659 7 P53350,P54652,Q96KQ7,O60216,P46379 5 +Positive regulation of cytoskeleton organization 0.3636972345639681 1.1242053038628737 0.2609259399220236 1.0 0.533852306336788 44 Q16625,O95429,P62993,P63000,P42345,P60981,P23396,Q9Y613,Q14203,Q9UQB8,P36405,Q15691,P14373,Q08722,P61586,Q7L576,Q00535 17 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.6463679452336881 1.1235659304156154 0.2611972162386049 1.0 0.5342367072875169 5 O43657 1 +Adp transport 0.6462291573060305 1.122993212936946 0.2614403769750595 1.0 0.5345633753278747 5 Q86VD7,O43808 2 +Mitochondrial transport 0.3336363399326609 1.121318080620389 0.262152492011193 1.0 0.5356774685243071 87 O95429,O75964,O43772,P55786,P50416,P62072,Q9P0J0,O60830,P00846,O95831,P56134 11 +Antigen processing and presentation via mhc class ib 0.5749513303050012 1.1187654883963982 0.2632401984754784 1.0 0.5372548163317616 3 Q03519,O00203 2 +Synaptic vesicle budding 0.5749513303050008 1.1187654883963962 0.2632401984754793 1.0 0.5372548163317616 3 O00203,Q13492 2 +Protein stabilization 0.3326188109040017 1.116198744230594 0.2643370719201501 1.0 0.5383228167634871 71 Q9H2J4,O95429,Q9BXJ9,Q99653,Q32P28,Q9UBV2,Q9NQC3,Q9P275,Q969V3,P46379,Q9HBM6,P41440,O95816,P83436,Q9Y2Z0 15 +Positive regulation of amyloid precursor protein catabolic process 0.645569620253168 1.1136552742928625 0.2654271037100275 1.0 0.5392724473093677 4 P07948,Q13492,Q96P70 3 +Protein acetylation 0.3425634299196159 1.112678997550247 0.265846318835699 1.0 0.5398113696715757 54 Q9UBU8,Q03164,Q96ES7,P46379,Q86UY6,Q12824,Q9UKN8,Q9P265 8 +Chemokine production 0.6103629918923823 1.112483248010093 0.2659304289021538 1.0 0.5398113696715757 8 P09601 1 +Calcium ion regulated exocytosis 0.5875150153524448 1.110825694682283 0.2666433842107778 1.0 0.5403081269947891 9 O00186,P51809,P04899,Q9BRK5,Q00535 5 +Negative regulation by host of viral process 0.5727763394378791 1.108824303991145 0.2675059836938285 1.0 0.5414354917986305 3 Q9H1E3 1 +Protein k48 linked ubiquitination 0.5447619176248611 1.107598791851412 0.2680351254431112 1.0 0.5421817422886598 11 Q05086,Q96PU5,Q96J02 3 +Negative regulation of cyclin dependent protein serine threonine kinase activity 0.6404676843130785 1.1068696822836233 0.2683502754834501 1.0 0.5426067074919484 6 P42771,P53350,O00410,P24468,O95373 5 +Dorsal ventral pattern formation 0.6438679623685515 1.1067004621270724 0.2684234555170128 1.0 0.5426067074919484 4 P31277 1 +Regulation of blood pressure 0.4467553612665226 1.105993642973933 0.2687292708981135 1.0 0.5430535360799101 17 Q14344,Q9NZ08,P09601,P24468,P61586,Q9HB40,P42785 7 +Regulation of amyloid beta clearance 0.5717014936863548 1.1039137843751274 0.2696305387727236 1.0 0.5441881636351819 3 Q13547 1 +Embryonic appendage morphogenesis 0.5626926257448994 1.102291732176982 0.270334862604682 1.0 0.5450944695768313 10 Q13547,Q07812,Q9NR56,Q9C0E8 4 +Signal peptide processing 0.640786165206972 1.100548840627172 0.2710930618243163 1.0 0.5464512756597139 5 P67812,P61009 2 +Activation induced cell death of t cells 0.5704088254380375 1.0980101871168435 0.2722000409589045 1.0 0.5483375667870258 3 P49327,Q9HCL2 2 +Positive regulation of smooth muscle cell proliferation 0.607060763060963 1.097715330764911 0.2723288132455224 1.0 0.5484245135651733 8 P08754,Q13547,P09601 3 +Cell morphogenesis involved in neuron differentiation 0.3320715348436687 1.0934327215475326 0.2742038533178261 1.0 0.5515545968511899 78 O15031,Q96PU5,Q9Y4F1,P07196,Q12955,Q96N67,Q9UQB8,O94813,P41440,Q05086,Q9P265 11 +Positive regulation of tyrosine phosphorylation of stat protein 0.5691109669046112 1.0920852288436769 0.2747956413170311 1.0 0.5519000934539842 3 P22059,P07948 2 +Neuron migration 0.4254080354055042 1.0919501506648768 0.2748550126228826 1.0 0.5519000934539842 21 O15031,P63000,Q07812,Q9BVA1,P24468,Q9H9T3,Q9Y4G8,Q93008,Q9BSJ2,P46109,Q00535,P43034 12 +Atp transport 0.6215387052781798 1.0899694111256786 0.2757266187347456 1.0 0.5533536089018735 7 Q86VD7,Q08722 2 +Response to molecule of bacterial origin 0.3853998952258169 1.0889219391816969 0.2761883105417118 1.0 0.5539228593151061 33 Q6PD62,Q9NUQ9,Q96RT1,O43823,Q86U42,P61586,P11802 7 +Integrin mediated signaling pathway 0.4697146004108899 1.0885759814884317 0.2763409132692926 1.0 0.5539228593151061 15 Q96RT1,Q13418 2 +Nucleotide sugar metabolic process 0.620301628376345 1.084647994509546 0.2780775894281708 1.0 0.5563288687935236 7 Q9NR45,P34949,O60762,Q9NYU2 4 +Rna destabilization 0.3790119511122828 1.0836013450954811 0.2785415941888423 1.0 0.5567355545627842 35 Q96B26,Q9NQT5,P62487,P67809,Q9HCE1,Q15024,Q96C86,Q13868,O15514,Q92945,Q969T7 11 +Positive regulation of signal transduction by p53 class mediator 0.5205334315739378 1.0824022307846102 0.2790738374860422 1.0 0.5575947138908022 12 P62841 1 +Regulation of actin filament length 0.3692780526175842 1.0822408367125265 0.2791455272319392 1.0 0.5575947138908022 39 O95429,Q9UEY8,Q9UQB8,P35611,Q96F07,O94813,P61586 7 +Negative regulation of smooth muscle cell migration 0.6360357360015957 1.08098886169668 0.279702068271316 1.0 0.5585322473023848 5 P61586,O94813 2 +Positive regulation of mitophagy in response to mitochondrial depolarization 0.5665152498377662 1.080242690214898 0.2800341226895251 1.0 0.5588469127567283 3 O95140,Q16543 2 +Lipophagy 0.6362477188977188 1.0755965863963792 0.2821077147525612 1.0 0.5620376814370125 4 Q9Y679 1 +Synapse organization 0.336644271699152 1.074915801127198 0.2824124269294636 1.0 0.5621920468956321 59 O15031,Q9Y4F1,Q12955,Q9UQB8,Q13614,Q9BRK5,Q05086,O15228 8 +Positive regulation of supramolecular fiber organization 0.3683304216784798 1.0738031429161143 0.282910921019526 1.0 0.5630094315163353 39 Q16625,O95429,P62993,P63000,P42345,P60981,P23396,Q9Y613,Q14203,Q9UQB8,P36405,Q15691,P14373,Q08722,P61586,Q7L576 16 +Regulation of dna binding transcription factor activity 0.3362553378372063 1.070713125381969 0.284298439268793 1.0 0.5650685082084667 59 O75381,Q9BXW9,Q96RT1,P09601,Q96J02,Q96HY6,P14373,Q14145,P41440,Q12824 10 +Muscle tissue development 0.3485274698396848 1.0675328002944715 0.2857313103394014 1.0 0.5672125113214149 48 Q68CP9,Q8NDZ4,P11310,P42345,P16989,Q9Y5Q8,P61586,P41440,Q9NQ29,Q9BYT8 10 +Postsynapse organization 0.3868985297380107 1.0609431960668625 0.2887157168975389 1.0 0.5707557469459212 31 Q05086,Q9UQB8,Q13614,Q9Y4F1 4 +Regulation of cyclin dependent protein kinase activity 0.4395616583678765 1.0601080066778596 0.289095465661922 1.0 0.5712181493620485 17 P42771,P14635,O00410,P24468,O95373 5 +Positive regulation of cell adhesion 0.3377882759035954 1.0597353552399509 0.2892650135077248 1.0 0.5712181493620485 53 P30825,O95429,Q9NUQ9,P46939,P50570,P55196,P23396,Q12955,Q13277,Q9HCM4,Q08722,Q53GQ0,P41440,Q9HCL2,P61586,Q13418 16 +Regulation of cytosolic calcium ion concentration 0.4163053909445333 1.0593293903108705 0.2894497944445193 1.0 0.5712308635895228 22 Q14344,P28161,Q00535,Q07812,P20020,P55061,P17252,P78417 8 +Regulation of glial cell proliferation 0.5617325541951922 1.0584501799499069 0.2898502525078692 1.0 0.5715623196559461 3 Q96G23 1 +Regulation of peptidyl lysine acetylation 0.4243685883446264 1.0568900304074138 0.2905617789565147 1.0 0.5722267227138762 20 Q03164,Q12824 2 +Regulation of endoplasmic reticulum unfolded protein response 0.5758192748384059 1.0563487425566942 0.2908089146602883 1.0 0.5722267227138762 9 Q96HY6 1 +Extrinsic apoptotic signaling pathway via death domain receptors 0.5346230057629136 1.0562638749118365 0.2908476754849174 1.0 0.5722267227138762 11 P09601,Q07812,Q13794 3 +Response to alcohol 0.3661590748592867 1.054508159481943 0.2916503269225428 1.0 0.5734536507875411 39 P07196,P50416,O43823,O94813,O95831,Q9BRK5,P61586,P11802 8 +Negative regulation of erad pathway 0.4914044761595727 1.0500683862292255 0.2936866723350926 1.0 0.5763960854713859 2 O43765 1 +Ras protein signal transduction 0.3348084455035993 1.048904903837554 0.2942218883291987 1.0 0.5770929016034437 58 P42771,Q14344,Q15392,Q96RT1,P50570,P57105,Q15555,Q15047,Q6IQ22,P24941,Q9UN86,P41440,P61586,Q7L576,Q92538 15 +Positive regulation of transcription elongation from rna polymerase ii promoter 0.5739188099453495 1.0475225998317823 0.2948586144273 1.0 0.5776570828983846 9 P50750 1 +Positive regulation of cell projection organization 0.3368084264855114 1.0474974124682668 0.2948702249574957 1.0 0.5776570828983846 52 O15031,Q16625,Q15555,Q32P28,Q9UQB8,O94813 6 +Trophectodermal cell differentiation 0.6291673118853833 1.0467637385908617 0.2952085584419879 1.0 0.5781430832709797 4 Q6PD62 1 +Chromosome organization involved in meiotic cell cycle 0.4324186495210761 1.0427278795917092 0.2970743417565658 1.0 0.5809091066216607 18 Q9BXW9,O60566,Q96KQ7,P46379,O94901,Q15021 6 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.4012481990905782 1.0394985492943425 0.2985729324048625 1.0 0.5831142776686975 25 Q12907,Q9Y282,Q6NUQ1,P24390,O75396,P83436,Q92538 7 +Copii coated vesicle cargo loading 0.5718201347307668 1.0377853227461582 0.299370011458786 1.0 0.5838732930504229 9 Q5JRA6,P62820,Q15436,O95487,O94979 5 +Protein localization to phagophore assembly site 0.5568007061858106 1.0360197276257248 0.3001929391402824 1.0 0.5839769110636651 3 P50851 1 +Regulation of protein kinase activity 0.3272959319338801 1.0356112827809028 0.3003835261156231 1.0 0.5841702696711237 82 Q8NDZ4,Q9UHD1,P49736,Q13432,O00410,Q96M27,Q9BRG1,Q9ULW0,Q9H7B4,P23396,P14373,P61586,Q96A49,P14635,Q9NQS7,O95373,P42771,P61981,P42345,P33121,Q9HAW4,Q9BZF1,P54619,P24468,Q99653 25 +Pallium development 0.3732805755652876 1.0352053653484392 0.3005730136460161 1.0 0.5841840793132217 35 P07196,P18887,Q8WXH0,Q9NQC3,Q13547,O94813,Q02218,P61586,O94901 9 +Negative regulation of ubiquitin protein ligase activity 0.5929253399265437 1.034712814371696 0.3008030497914338 1.0 0.584228769669947 8 P62841 1 +Long chain fatty acyl coa metabolic process 0.5302679104811044 1.034292735024506 0.3009993321579047 1.0 0.584228769669947 11 Q9UKU0,Q53GQ0,P33121 3 +Neuron projection extension 0.385636267029428 1.0339382365182217 0.3011650381955775 1.0 0.584228769669947 30 Q96PU5,P50570,Q9NQC3,Q96F07,O94813,Q7L576,Q00535,Q9P265 8 +Regulation of protein acetylation 0.4126584828569447 1.0338308305117787 0.3012152558245344 1.0 0.584228769669947 22 Q03164,Q12824 2 +Cytosolic transport 0.3333288229989763 1.0331020809526172 0.3015561296256361 1.0 0.5843471032460921 58 Q7Z3U7,P49257,Q14203,O60749,O43752,A4D1P6,O14976,Q9C0C9,Q99570,Q13614,Q9UBQ0,Q92538,O95782,Q96RL7,P14373,O94832,P40616,Q8N2H4,O95249,P53367,Q96QK1 21 +Negative regulation of tor signaling 0.5561323815704078 1.0329836579189713 0.3016115464428113 1.0 0.5843471032460921 3 Q13131,O75340 2 +Cellular response to reactive nitrogen species 0.6082179371969545 1.0328005495224435 0.301697246535463 1.0 0.5843471032460921 7 O95831,P50570 2 +Response to nitric oxide 0.6082179371969545 1.0328005495224435 0.301697246535463 1.0 0.5843471032460921 7 O95831,P50570 2 +Regulation of transcription elongation from rna polymerase ii promoter 0.4351849048323526 1.0323014676231297 0.3019309137783965 1.0 0.5843471032460921 17 P35269,Q8IXH7,Q8WX92,P50750 4 +Adenylate cyclase activating g protein coupled receptor signaling pathway 0.6233766233766223 1.0290191409068152 0.3034706804292986 1.0 0.5862584978377825 5 P04899,P17252,Q14344,Q9Y4G8 4 +Trabecula morphogenesis 0.5551114009621442 1.0283472464181231 0.3037865140029876 1.0 0.5866030646338742 3 P61586 1 +Positive regulation of catabolic process 0.2930136728055802 1.0281113609156178 0.3038974471150282 1.0 0.5866030646338742 130 Q8TBX8,Q9Y371,Q96HY6,Q969T7,Q8WU17,P62487,P31751,Q13868,Q92945,P14373,O75396,P09601,O15269,Q9Y5A7,P67809,Q9NQT5,Q07812,Q96J02,Q14145,P12235,Q96PU5,Q96B26,P50416,O00178,O95816,O15514,O43847,P46379,Q9P0J0 29 +Telencephalon development 0.3660059376754621 1.027143513688347 0.3043528915973561 1.0 0.5872544046905612 37 P07196,P18887,Q8WXH0,Q9NQC3,Q13547,O94813,Q02218,P61586,O94901 9 +Maintenance of dna methylation 0.6224225042600992 1.025112484152204 0.3053101155941546 1.0 0.5883787499037848 5 Q93009,Q96T88 2 +Lipid storage 0.4589860489936549 1.024932920839749 0.3053948397486863 1.0 0.5883787499037848 15 Q9H6V9,P50416 2 +Detection of abiotic stimulus 0.6059473355799228 1.0230877459431893 0.3062663602768563 1.0 0.5891769513201489 7 Q13432 1 +Positive regulation of protein targeting to membrane 0.5686226788952766 1.0229698979224977 0.3063220786803513 1.0 0.5891769513201489 9 P31751,Q9UHD1,Q99653,Q12955,Q86YS7 5 +Regulation of protein targeting to membrane 0.5686226788952766 1.0229698979224977 0.3063220786803513 1.0 0.5891769513201489 9 P31751,Q9UHD1,Q99653,Q12955,Q86YS7 5 +Protein localization to endoplasmic reticulum exit site 0.6213898003556627 1.0208858474254376 0.3073085250900531 1.0 0.5904674300320577 5 Q9UHQ4,Q5JRA6 2 +Negative regulation of neuron differentiation 0.6052773771341314 1.0202238799091827 0.3076222947089588 1.0 0.5908930794319611 7 P26196,Q15648,P61586 3 +Positive regulation of jun kinase activity 0.5527692454472082 1.0177192243246354 0.3088114085748725 1.0 0.5924558599864327 3 P23396 1 +Nucleoside monophosphate catabolic process 0.6220128739600573 1.017706412731593 0.3088174988266541 1.0 0.5924558599864327 4 O43598,P49902 2 +Regulation of cell adhesion mediated by integrin 0.5523409259591379 1.0157768766527318 0.309735649717223 1.0 0.5937063351551557 3 P46109 1 +Response to lipid 0.2924940850245163 1.0136509597940329 0.3107493321335868 1.0 0.5947906610986909 132 O75376,Q86X55,O43823,Q96HY6,Q13547,O94813,Q6PD62,Q13126,Q9H7B4,Q96RT1,P61586,P11802,Q86U42,Q05086,Q9NUQ7,Q9NVR5,O95831,O15228,P33121,P07196,O75874,P50416,P10620,Q9P0J0 24 +Alcohol catabolic process 0.5660043336645073 1.0108566206787668 0.3120850587337851 1.0 0.5967811600742172 9 P30837,Q10713,Q13614 3 +Negative regulation of low density lipoprotein particle clearance 0.5506432257592595 1.0080820255235887 0.3134150858668778 1.0 0.5991456401262965 3 Q92945 1 +Skeletal muscle organ development 0.3993883186227632 1.0070664333833266 0.3139028504339283 1.0 0.5996432975050918 24 P51114,P50402,P16989,Q13131,Q9Y5Q8,P61586,P24468,P41440,Q9BYT8,Q00535 10 +Stem cell division 0.6191835041899107 1.0062389293889762 0.3143006497994753 1.0 0.5997646597007564 4 Q01085 1 +Dna methylation dependent heterochromatin assembly 0.5245934134644881 1.005748090509219 0.3145367634131961 1.0 0.6000364819609691 11 Q15047,Q96JM7 2 +Skeletal muscle contraction 0.5499911011800098 1.005127948013072 0.3148352440690936 1.0 0.6002567668912547 3 P78417 1 +Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.5499675535366664 1.0050212966791794 0.3148865951559165 1.0 0.6002567668912547 3 P11940,A5YKK6 2 +Modified amino acid transport 0.6158558426000856 1.0049242163459398 0.3149333427289271 1.0 0.6002567668912547 6 O43772 1 +Ventricular system development 0.6154839748662592 1.003391827375345 0.3156718457531609 1.0 0.6011277776143723 6 Q9H6E4 1 +Production of molecular mediator of immune response 0.3773789186806455 1.003105643113225 0.3158098922430259 1.0 0.601211937506337 32 P09601,Q9UQ84 2 +Mitochondrial transmembrane transport 0.3313109645298071 1.0019838799148988 0.3163513784849767 1.0 0.6020638534090199 56 Q6P4A7,Q96NB2,O75964,Q9NUT2,O43772,Q9BQT8,P50416,Q9BSK2,O60830,P00846,O95831,P56134,O96008 13 +Regulation of adenylate cyclase activity 0.6178459250467223 1.0008227380859818 0.316912514590876 1.0 0.6022391943939743 4 P08754,Q13586 2 +Regulation of cyclase activity 0.6178459250467223 1.0008227380859818 0.316912514590876 1.0 0.6022391943939743 4 P08754,Q13586 2 +Peptidyl arginine methylation 0.6176566049983812 1.0000564022721472 0.3172832132353633 1.0 0.6025841280716684 4 Q86X55,O14744,O60678 3 +Peptidyl arginine n methylation 0.6176566049983812 1.0000564022721472 0.3172832132353633 1.0 0.6025841280716684 4 Q86X55,O14744,O60678 3 +Fatty acid transmembrane transport 0.5842625246506248 0.9963060238806906 0.3191014778130294 1.0 0.6051403395116242 8 P33121,O43772 2 +Cellular response to hormone stimulus 0.3031565155108273 0.9939944205647708 0.3202255837789254 1.0 0.6065358756590771 116 Q9HCD5,O75376,Q86X55,O43823,Q9BSK2,Q9UQB8,Q96HY6,Q13547,Q6IQ22,O94813,Q8IZL8,Q86YS7,P42785,Q9H7B4,P31751,P43490,P61586,P11802,Q05086,Q96A49,Q9NUQ7,O95831,P33121 23 +Establishment of centrosome localization 0.5474321137156262 0.9935452709087416 0.3204443000963626 1.0 0.60660939314932 3 Q9Y613 1 +Positive regulation of mrna metabolic process 0.3300148918644915 0.9927903428115312 0.3208121371348784 1.0 0.6069470025062113 57 Q96B26,P62487,Q9NQT5,P67809,Q9HCE1,Q14011,Q15024,O00178,Q15427,Q96C86,Q13868,O15514,Q92945,Q13595,P38159,P98179,Q969T7 17 +Regulation of postsynapse organization 0.4288125028945139 0.9919905135915807 0.3212021530302964 1.0 0.6075054597909888 17 Q9UQB8 1 +Modification dependent macromolecule catabolic process 0.2881827648955916 0.9908716170023376 0.3217482732632315 1.0 0.6079998343729385 171 Q9H7D7,Q96T88,A4D1P6,Q96HY6,Q96KB5,Q9BRG1,O15372,Q8WU17,Q9UJX3,Q9H1A4,Q9BZK7,Q9UHG3,Q9UBV2,Q86UV5,Q13868,Q9Y385,Q15369,Q96K76,Q9NRR5,Q05086,Q9H2J4,Q9Y5A7,Q92575,Q9NQT5,P45974,P49427,Q96J02,Q9UJX4,Q14145,Q16763,Q9Y679,Q9Y5K6,Q96PU5,Q8IXB1,Q96B26,Q13616,O43791,O95816,Q9P275,P24941,O00231,P46379,Q5T4S7 43 +Plasma membrane tubulation 0.5465913560631446 0.9897431144550676 0.3222996956846624 1.0 0.6085253740392507 3 Q9Y371 1 +Positive regulation of cell cell adhesion 0.3886113300419537 0.9894909375802176 0.3224230016073561 1.0 0.6085465966508472 27 P30825,Q9NUQ9,P23396,Q12955,Q08722,P55196,P41440,Q9HCL2,P61586 9 +Positive regulation of histone ubiquitination 0.612969720666565 0.9864981402905368 0.3238887273868305 1.0 0.6106036455679918 5 P50750 1 +Hormone mediated signaling pathway 0.3565025792132205 0.9835813422920798 0.3253214025349724 1.0 0.6120858795134027 40 Q9NUQ7,P33121,O75376,Q86X55,Q96HY6,P61586,P42785,Q05086 8 +Myelin maintenance 0.5442438529759673 0.9791360956656052 0.3275127387480721 1.0 0.6149419554069975 3 Q9Y2J2 1 +Regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.5800770692403676 0.9778153364725364 0.3281656644069655 1.0 0.6155868949314849 8 P09601 1 +Interferon gamma production 0.5799884493663325 0.97742432600922 0.3283591247797881 1.0 0.6157694828276705 8 Q9NUQ9,Q08722,P14373 3 +Amyloid beta clearance by transcytosis 0.6105988704525013 0.976841019364172 0.3286478650435098 1.0 0.6160920474896315 5 P20339,Q13492,Q15907 3 +Smooth muscle cell proliferation 0.4175335888609887 0.9766883169088314 0.3287234808491353 1.0 0.6160920474896315 19 P09601,Q13547,P61586 3 +Positive regulation of vascular associated smooth muscle cell proliferation 0.6116787453858911 0.9758947803325286 0.329116609017154 1.0 0.6166484344439568 4 O95140,P08754 2 +Retina morphogenesis in camera type eye 0.6114237532083602 0.9748657387596196 0.3296268629228538 1.0 0.6169588278318886 4 Q15555 1 +Cytoplasmic sequestering of transcription factor 0.608528833982608 0.9747838096292716 0.3296675097827903 1.0 0.6169588278318886 6 Q14145 1 +Positive regulation of dna templated transcription elongation 0.4256718043877622 0.9722076833624878 0.3309472389562606 1.0 0.6189069999471782 17 Q86V81,P50750 2 +Meiosis i cell cycle process 0.4077698755197715 0.9710210035303548 0.3315378195188576 1.0 0.6197348327510366 21 Q9BXW9,P53350,P54652,O60216,Q96KQ7,Q96B01,Q03188,P46379,P49959,O94901,Q92878 11 +Establishment of protein localization to membrane 0.3202817308645941 0.9612787097602364 0.3364120498019625 1.0 0.6259237847898262 88 Q9HD20,P61619,Q5BJH7,Q86YS7,Q9P0I2,P31751,Q12955,P62072,Q9BZG1,Q9BRK0,P98194,Q13277,Q07812,Q8N2H4,P09132,P55196,P46379,Q99653,Q15070,O60725,Q9P0J0,Q9NPA0 22 +Positive regulation of neuron projection development 0.3976889154204251 0.9607102267856344 0.3366978876905837 1.0 0.6262737132827757 23 Q9UQB8,Q32P28 2 +Aerobic respiration 0.3180774440199363 0.9582995177041344 0.337911746953031 1.0 0.6279845230580554 94 P13073,P03886,Q9BSK2,P00846,Q16718,Q02218,O43676,P48735,P08574,P61586,Q9P2R7,P14635,O95168,Q13423,O75964,O75874,O96000,P56134,Q15070 19 +Viral rna genome replication 0.446855114379968 0.953582846932 0.3402948418058691 1.0 0.6311316608594086 15 Q15047 1 +Regulation of dna repair 0.3344035570993486 0.9506020282884478 0.3418064386175361 1.0 0.633385029153583 49 Q68CP9,Q9UBU8,O95071,Q9UNS1,P18887,P23396,Q9NRR5,Q96T76,P35637,Q96B01,P50750,Q96S55,Q9NY27,O14757,O96028 15 +Appendage development 0.4341095707493976 0.9480052903790862 0.3431267609629103 1.0 0.6353518601471028 16 Q9C0E8,Q15648,Q07812,Q9NR56,Q13547,P24468 6 +Vitamin k metabolic process 0.5370865741705904 0.9468847436490564 0.3436975128597739 1.0 0.6361532121871457 3 Q9Y5Z9 1 +Vesicle transport along microtubule 0.5305335529905862 0.9466337999226996 0.3438254144067794 1.0 0.6362061249826194 10 O14617,O00203,O95295,P62820,Q9Y2T2,P43034 6 +Microtubule nucleation 0.5125918060487133 0.9457336899959452 0.3442844343695137 1.0 0.6363202788722173 11 Q9ULW0,Q96P70,Q96CW5 3 +Protein deneddylation 0.572158155907665 0.9429626764936716 0.3456999940767669 1.0 0.6382000467019506 8 P61201,Q13098,Q9BT78 3 +Exocytic process 0.4447290518882947 0.9411581717429802 0.3466238084599993 1.0 0.6390040492590897 15 O00186,Q9UNH7,P51809,P61026,P56545,Q13277,O95295,Q6IQ22,O00161 9 +Rhythmic process 0.3257910399034839 0.941137773585683 0.3466342602521599 1.0 0.6390040492590897 55 Q9UNS1,Q03164,O75376,P43490,Q13547,Q9Y2K7,O94813,Q05086 8 +Synaptic vesicle recycling 0.4552749434262156 0.9371713605628346 0.3486704190388248 1.0 0.6417997729558677 14 O00203,P50570,Q96CW1,Q13492,O14976,P20339,Q7L576,Q00535 8 +Pyrimidine nucleoside triphosphate metabolic process 0.5104480443937987 0.935071572715158 0.3497514154721102 1.0 0.6429003063168832 11 P17812,O75414 2 +Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.598749740694095 0.9347464046848633 0.3499190059384873 1.0 0.6430238531388267 6 Q96K76 1 +Cellular response to vitamin 0.5972438433338454 0.9286022715811066 0.3530952442104205 1.0 0.6470046151063941 6 O15164,Q15648,Q8TB36,Q96C86 4 +Non motile cilium assembly 0.5261967174927233 0.925891369570634 0.354502436867036 1.0 0.6486554157584211 10 Q15555,Q15691,O00471,P50570 4 +Interstrand cross link repair 0.5977032229466516 0.924537145110302 0.3552067211888354 1.0 0.6494961254864008 5 Q9BXW9 1 +Microtubule anchoring 0.5960902682521958 0.9238997230925576 0.3555385272789499 1.0 0.6496234471617095 6 O75381,Q14203 2 +Ruffle assembly 0.506748316340373 0.9167165255039764 0.3592912041854066 1.0 0.6551720620585582 11 O95429,P63000,Q7L576 3 +Positive regulation of wound healing spreading of epidermal cells 0.5302109688860936 0.9160410615599578 0.3596453587273163 1.0 0.6553547480297599 3 P42345 1 +Rna surveillance 0.5065388307092937 0.9156790215677464 0.3598352712425632 1.0 0.6553547480297599 11 Q96B26,Q9NQT5 2 +Regulation of vascular permeability 0.5805994532124823 0.9154723941542112 0.3599436884097642 1.0 0.6553547480297599 7 Q16625 1 +Activation of protein kinase activity 0.5063851519114252 0.9149180330426354 0.3602346623777652 1.0 0.6553547480297599 11 Q9HAW4,Q9BZF1,P42345,Q96M27 4 +Regulation of amyloid precursor protein catabolic process 0.4883869347790175 0.9145756999936808 0.3604144204353487 1.0 0.6553547480297599 12 Q9NQC3,Q16799 2 +Brainstem development 0.4644826467726104 0.912434323006204 0.3615401282280741 1.0 0.6570286699089484 2 P22102 1 +Protein localization to vacuole 0.4396594895061363 0.9116414356389798 0.3619575024667028 1.0 0.6574141652400618 15 P20645,Q96RL7,Q9Y371,Q9NQC3,Q99570 5 +Cellular response to molecule of bacterial origin 0.3905462499979772 0.9107580909486688 0.3624228486573995 1.0 0.6578863044769909 23 Q9NUQ9,O43823,Q86U42,P61586,P11802 5 +Calcium ion transport into cytosol 0.4505187033463377 0.9103641430091416 0.362630501288276 1.0 0.6579116785885103 14 P28161,P07948,Q07812,P55061,P17252,P78417 6 +Mast cell activation involved in immune response 0.591662652677719 0.9058847009369098 0.3649968828449634 1.0 0.661060229433089 6 P09601 1 +Negative regulation of vascular associated smooth muscle cell migration 0.5277781498391515 0.9051632696600072 0.3653788974812828 1.0 0.6615650698883826 3 P61586 1 +Replication fork processing 0.521795222176235 0.9049160578353348 0.3655098592985264 1.0 0.6616151903550043 10 Q86V81 1 +Regulation of neuron projection development 0.3194704488642208 0.9034429489285816 0.3662908542555612 1.0 0.6626543949057115 61 O15031,Q96PU5,P07196,Q86X55,Q32P28,Q9NQC3,Q9UQB8,Q13555,O94813,P61586,Q05086,Q9P265 12 +Positive regulation of dna repair 0.3686116888825323 0.901473790972838 0.3673364628264215 1.0 0.6641708667417601 30 Q68CP9,Q9UBU8,Q9UNS1,P18887,P23396,Q96T76,P35637,Q96B01 8 +Retrograde transport endosome to golgi 0.3666592873139709 0.901158927131024 0.3675038255332112 1.0 0.6642007620839688 31 P40616,P49257,Q14203,O60749,O95249,Q96QK1,O43752,P14373,Q9C0C9,Q9UBQ0,P53367,Q92538 12 +Amyloid precursor protein metabolic process 0.4102524229034554 0.9006626109129402 0.3677677338607301 1.0 0.6642007620839688 18 Q15392 1 +Sequestering of calcium ion 0.437478091097066 0.8989911068944616 0.3686573975794327 1.0 0.664575437899753 15 P78417,Q07812,P28161 3 +Minus end directed organelle transport along microtubule 0.525957170668404 0.8970341819185029 0.369700677596932 1.0 0.6654404441376641 3 Q14204,Q8TD16 2 +Mammary gland epithelium development 0.5614517120073913 0.8961521451377348 0.3701715102583354 1.0 0.6660361086533805 8 Q9NQC3,Q15648,Q07812,P31751 4 +Diadenosine polyphosphate metabolic process 0.5253973498052623 0.8945373655257466 0.371034446901316 1.0 0.6664655837909994 3 Q9BW91 1 +Regulation of protein polymerization 0.3211830701024444 0.8940423012532223 0.3712992586231642 1.0 0.6664655837909994 55 Q16625,Q9NUQ9,O95429,P62993,P63000,Q9UEY8,P42345,P23396,Q14203,O15145,Q9UQB8,P35611,Q15691,Q96F07,O94813,P61586,Q7L576,Q9BPX3 18 +Regulation of protein serine threonine kinase activity 0.3325761679215209 0.8934379118940395 0.3716227076649157 1.0 0.6664655837909994 47 P30040,Q8NDZ4,Q9UHD1,P10644,P18031,P49736,Q9P287,O00410,P31689,P23396,O00571,Q96A49,P61586,P14635,Q9NQS7,P41240,O95373,P42771,P33121,P53350,P54619,Q9Y4R8,P24468 23 +Tricarboxylic acid cycle 0.392145033157095 0.8922647058404615 0.372251067132189 1.0 0.6668457315572714 22 Q13423,Q9P2R7,P48735,O75874 4 +Aminoacyl trna metabolism involved in translational fidelity 0.5183303992255291 0.8884622692709938 0.3742921429208765 1.0 0.6692924581545733 10 P26640,Q5JTZ9,Q9P2J5,Q9NSE4 4 +Negative regulation of anoikis 0.5238628584401461 0.8876991479263344 0.3747026043749848 1.0 0.66973908583319 3 Q07820 1 +Cellular response to biotic stimulus 0.3664168471616545 0.8846626294407612 0.3763386169183906 1.0 0.6717261576983033 30 Q9NUQ9,Q9UM00,O43823,Q86U42,P61586,P11802 6 +Protein localization to cytoplasmic stress granule 0.5876756385333436 0.8841638897723905 0.3766077482524492 1.0 0.6718250028806507 5 O00571,P67809 2 +Nik nf kappab signaling 0.4234064409519956 0.8836859028330348 0.3768657923375262 1.0 0.6719182481809611 16 P61586,O43657,Q13418 3 +Mammary gland epithelial cell proliferation 0.5856525809062516 0.8815227346550731 0.3780349544027506 1.0 0.6736277935755273 6 Q9NQC3,Q15648,Q07812 3 +Cilium movement 0.537683510918758 0.8811742346982134 0.3782235224955967 1.0 0.6737763862922116 9 Q9NVR5 1 +Nuclear body organization 0.5878346951535707 0.8803366356481926 0.3786769716286011 1.0 0.6741377436995584 4 P78362 1 +Intracellular lipid transport 0.4340593596258842 0.8792306125373864 0.3792762493311439 1.0 0.674713594339158 15 Q9P260,O43772 2 +Fatty acyl coa metabolic process 0.4064105334801031 0.8764063504201612 0.3808091672581115 1.0 0.6763249212723871 18 Q9UKU0,Q53GQ0,A8MXV4,P33121 4 +Response to interleukin 4 0.55675815597012 0.8757578301294496 0.3811616994775657 1.0 0.6764049348347402 8 P49736,P11802,Q14145 3 +Long chain fatty acyl coa biosynthetic process 0.5567515376000858 0.8757291309434772 0.3811773048319407 1.0 0.6764049348347402 8 Q9UKU0,Q53GQ0,P33121 3 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.4100992317881758 0.8751124486302887 0.3815127242912355 1.0 0.6766252801244891 17 P46379,Q8IXB1,Q13794,O95831,O60313 5 +Ncrna 3 end processing 0.3851831709825277 0.8735916226832305 0.382340689997533 1.0 0.6774280010096959 23 Q13868,Q96SY0,Q96B26,Q9NQT5 4 +Iron ion homeostasis 0.4098072816651794 0.8733100933920322 0.3824940804951717 1.0 0.6774280010096959 17 P09601,Q9Y487 2 +Negative regulation of cytokine production 0.3847857495695396 0.8708501366200743 0.3838359858369766 1.0 0.6785927081386657 23 Q9Y5K6,Q96RT1,O43823,Q96J02,P14373,P09601 6 +Regulation of nik nf kappab signaling 0.4317599283842032 0.8659868373690284 0.3864973800790481 1.0 0.6813159649935009 15 P23396,P61586,O43657,Q13418 4 +Transcription initiation from rna polymerase ii promoter 0.3743337045306383 0.8632221614987293 0.3880153312304879 1.0 0.6830519955654042 26 P62487,P35269,Q15648,Q9Y2X0,Q6P2C8,O15514,P50750,O60244,P11802 9 +Appendage morphogenesis 0.4603414793630277 0.8626885434808108 0.3883087330111869 1.0 0.6832253660213339 13 Q9C0E8,Q15648,Q07812,Q9NR56,Q13547 5 +Late endosome to vacuole transport 0.5818931415129951 0.8610184157743467 0.3892279004299648 1.0 0.6844342383075362 5 Q99570 1 +Rna stabilization 0.3681763368447599 0.860611370247707 0.3894521215131921 1.0 0.6846405846359793 28 P67809,Q92804,Q14011,P16989,O95453,P35637,P98175,Q08J23 8 +Somatic diversification of immunoglobulins involved in immune response 0.4414874668156728 0.8598497833596807 0.3898718527463611 1.0 0.6847626009662796 14 Q9UQ84 1 +Immunoglobulin production involved in immunoglobulin mediated immune response 0.4414874668156728 0.8598497833596807 0.3898718527463611 1.0 0.6847626009662796 14 Q9UQ84 1 +B cell activation involved in immune response 0.4414874668156728 0.8598497833596807 0.3898718527463611 1.0 0.6847626009662796 14 Q9UQ84 1 +Histone h2b ubiquitination 0.5798278133062913 0.8580207248014052 0.3908810196180128 1.0 0.6856472649706983 6 P50750 1 +Embryonic digit morphogenesis 0.5667341977372513 0.8573983945037965 0.3912247462873366 1.0 0.6858745825716142 7 Q13547,Q9C0E8 2 +Cerebral cortex neuron differentiation 0.5167171684568934 0.8559701770469725 0.3920142756733038 1.0 0.6861605315935275 3 P43034 1 +Positive regulation of cell development 0.3202191280717611 0.8559408005018031 0.3920305253874978 1.0 0.6861605315935275 51 O15031,P07196,Q9UQB8,P35611,Q16706,O94813,P55209,Q13418 8 +Cellular response to fatty acid 0.579041811597224 0.8548580192425191 0.3926297537763419 1.0 0.6865611032918237 6 P50416 1 +Protein destabilization 0.551908131137991 0.854773144436423 0.3926767483015076 1.0 0.6865611032918237 8 Q8WU17,P78527,Q9BUN8,Q68CQ4,Q96QK1 5 +Maintenance of location 0.3153128292777549 0.8547725049547116 0.3926771023905377 1.0 0.6865611032918237 60 Q9H6V9,P50416,Q96RL7,Q12955,P24390,P78417 6 +Negative regulation of rna catabolic process 0.3564197209114896 0.8547526678255856 0.3926880865534252 1.0 0.6865611032918237 33 P67809,Q92804,Q99729,Q14011,P16989,O95453,P35637,P98175,Q08J23,Q9NP64 10 +Calcium ion export 0.5811033702528583 0.8536439262990497 0.3933023120748167 1.0 0.6872598502867637 4 P20020 1 +Pteridine containing compound metabolic process 0.4063592800273361 0.8520803092708171 0.3941695199812733 1.0 0.6885873861467241 17 Q8IYS1,P61457,P41440,P00374 4 +Regulation of double strand break repair via homologous recombination 0.3723945987903828 0.8492957506084144 0.3957167448009269 1.0 0.6907332656465 26 Q68CP9,Q9UBU8,Q9UNS1,Q96T76,Q9NRR5,Q96B01,Q9NY27,O14757 8 +Negative regulation of immune system process 0.3411150215355569 0.8492874396286283 0.3957213682364431 1.0 0.6907332656465 40 Q5JRA6,Q14166,Q96J02,P28070,Q08722,P14373,O94813,P09601,Q9HCL2 9 +Negative regulation of epidermal growth factor activated receptor activity 0.5796819214540776 0.8480257601760081 0.3964236246703918 1.0 0.6910176162281715 4 Q9BRG1,Q9UNH7,Q99816 3 +Regulation of epidermal growth factor activated receptor activity 0.5796819214540776 0.8480257601760081 0.3964236246703918 1.0 0.6910176162281715 4 Q9BRG1,Q9UNH7,Q99816 3 +Type i interferon production 0.3891578427344811 0.8460444045635132 0.397527973259447 1.0 0.6923774324904888 21 P41440,Q9NUD5,Q96J02 3 +Protein modification by small protein removal 0.342129230346233 0.8455644335882319 0.3977957736042696 1.0 0.6924673167687369 39 Q96ES7,Q9H4L4,Q96J02,Q86UV5,Q9H8M7,Q9P275,Q96K76,Q13098,Q9BT78 9 +Protein targeting to membrane 0.3551861951566075 0.8450535060401895 0.3980809656541408 1.0 0.6927681237743701 33 P61619,P31751,P09132,Q99653,Q12955,Q5BJH7,P46379,Q86YS7,O60725 9 +Positive regulation of interferon gamma production 0.5777445505849719 0.8444801514859482 0.3984011501693381 1.0 0.6927681237743701 5 Q9NUQ9,P14373 2 +Nucleoside triphosphate biosynthetic process 0.3570571054472157 0.8425692913567369 0.3994693716476809 1.0 0.6942487234875323 32 O75964,O75414,P17812,P00846,P56134 5 +Regulation of oligodendrocyte differentiation 0.5757715914366495 0.8417225097701342 0.3999432954594404 1.0 0.6948544723739298 6 Q13547,P42345 2 +Base excision repair 0.4274264142579476 0.8411368448396075 0.4002712760814466 1.0 0.6950766588717124 15 P18887,Q96K76,P29372 3 +Organic hydroxy compound catabolic process 0.5080405245753051 0.8399277021416787 0.4009489242660189 1.0 0.6954992712829995 10 P30837,Q13614 2 +Golgi to plasma membrane transport 0.3734108788027826 0.838676610913513 0.4016508067618112 1.0 0.6963396666078924 25 Q4J6C6,Q8N2H4,Q567U6,P50570,P98194,P61026,Q9NV70,Q12955,Q9BZG1,Q96KP1,P36405,O00471,P41240 13 +Negative regulation of transport 0.3082936945650396 0.8384334951617558 0.4017872841617551 1.0 0.6963878090747303 71 P17858,Q9UHD1,P49257,Q13432,Q13614,Q7L576,Q00535,P63000,P31751,Q12955,P14373,Q08722,Q9Y385,P09601,P78417,P80404,Q13492,Q6WKZ4,P41240,Q96PU5,O95429,P28161,P55061,Q99653,P53367,Q96QK1 26 +Ruffle organization 0.4375179815086369 0.8378257168408251 0.4021285931654992 1.0 0.696790848747143 14 O95429,P42345,Q9UHB6,P63000,Q7L576 5 +Cellular response to steroid hormone stimulus 0.3183049611794799 0.837306019841741 0.4024205763752511 1.0 0.6969937672147075 51 Q9H7B4,Q9NUQ7,O75376,Q86X55,Q96HY6,O95831,P61586,Q05086 8 +Positive regulation of fibroblast proliferation 0.5745010314551178 0.8366293598263586 0.4028009371229988 1.0 0.6972015139718806 6 P14635 1 +Polyadenylation dependent snorna 3 end processing 0.5741870037637153 0.8353714610770424 0.403508593217142 1.0 0.6980491623410779 6 Q9NQT5 1 +Regulation of defense response to virus 0.4368569203176609 0.8341693522381901 0.4041855588260092 1.0 0.6988428312656992 14 Q8IZ81,O43657 2 +Cilium or flagellum dependent cell motility 0.5470630840894009 0.8339071357837111 0.4043333158322988 1.0 0.6989096657371038 8 Q9NVR5 1 +Histone h3 acetylation 0.414808212207629 0.8326454837852609 0.4050446989825751 1.0 0.6996683075104306 16 Q03164,Q12824 2 +Regulation of phosphorus metabolic process 0.2716293051990717 0.8325476963425639 0.4050998677109252 1.0 0.6996683075104306 201 O15031,Q16625,Q8TBX8,Q8NDZ4,Q9UHD1,P49736,O75376,Q13432,O43823,O00410,A4D1P6,Q96HY6,Q13614,Q96M27,Q99570,O94813,P41440,Q9BRG1,Q96KB5,Q9ULW0,Q00535,Q13418,Q9NY27,Q9H7B4,P78318,P31751,P23396,Q92797,P14373,P50750,P61586,Q96A49,Q9H2J4,Q05639,P14635,Q13217,Q07812,Q96N67,Q9NQS7,Q9UJZ1,O95373,P42771,O95429,P61981,Q8IXB1,P51114,P33121,P42345,Q9HAW4,Q9BZF1,O75874,P54652,Q8WTV0,P49959,P54619,P24468,Q99653 57 +Folic acid metabolic process 0.5604935074487499 0.8314864079129564 0.4056989035297376 1.0 0.7005140636149594 7 P41440,P00374 2 +Synaptic vesicle cytoskeletal transport 0.5751379422265541 0.8301118375139059 0.4064755548947873 1.0 0.7011213411245331 4 Q9Y2T2,O00203,O95295 3 +Spindle assembly 0.3296979215548248 0.8291984660630666 0.4069921128270521 1.0 0.7011213411245331 45 O75376,Q15555,P23396,P52732,Q8N3U4,Q9H6D7,Q9NQS7,Q15691,Q96CW5,Q9ULW0,P61586 11 +Cellular transition metal ion homeostasis 0.3827814785483898 0.8289889696174023 0.4071106488877203 1.0 0.7011213411245331 22 P09601,O43819 2 +Regulation of rac protein signal transduction 0.5747356256959926 0.8285292245669629 0.4073708513220779 1.0 0.7011213411245331 4 P50570 1 +Imp metabolic process 0.4883540820815612 0.826444560587225 0.4085519546119243 1.0 0.7011213411245331 11 P30520 1 +Nephron tubule epithelial cell differentiation 0.4472915990917817 0.8260331544008928 0.4087852847458828 1.0 0.7011213411245331 2 P42224 1 +Cell differentiation involved in metanephros development 0.4472915990917817 0.8260331544008928 0.4087852847458828 1.0 0.7011213411245331 2 P42224 1 +Regulation of epithelial cell differentiation involved in kidney development 0.4472915990917817 0.8260331544008928 0.4087852847458828 1.0 0.7011213411245331 2 P42224 1 +Renal vesicle development 0.4472915990917817 0.8260331544008928 0.4087852847458828 1.0 0.7011213411245331 2 P42224 1 +Metanephric nephron morphogenesis 0.4472915990917817 0.8260331544008928 0.4087852847458828 1.0 0.7011213411245331 2 P42224 1 +Metanephric renal vesicle morphogenesis 0.4472915990917817 0.8260331544008928 0.4087852847458828 1.0 0.7011213411245331 2 P42224 1 +Mesenchymal to epithelial transition involved in metanephros morphogenesis 0.4472915990917817 0.8260331544008928 0.4087852847458828 1.0 0.7011213411245331 2 P42224 1 +Positive regulation of mesenchymal cell proliferation 0.4472915990917817 0.8260331544008928 0.4087852847458828 1.0 0.7011213411245331 2 P42224 1 +Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 0.4472915990917817 0.8260331544008928 0.4087852847458828 1.0 0.7011213411245331 2 P42224 1 +Metanephric nephron development 0.4472915990917817 0.8260331544008928 0.4087852847458828 1.0 0.7011213411245331 2 P42224 1 +Peptidyl lysine methylation 0.3363806731125715 0.822062047987147 0.411041583974107 1.0 0.703144888300249 41 Q03164,Q9H7B4,Q15047 3 +Antiviral innate immune response 0.5720866990307234 0.8220222155724015 0.4110642533069673 1.0 0.703144888300249 5 Q9NVI7,Q92667 2 +Positive regulation of organelle assembly 0.3814200389793 0.8198746646158384 0.4122875611261993 1.0 0.7043506106084768 22 Q8TBX8,Q15555,Q9Y371,Q9UN86,P61586 5 +Neurotransmitter secretion 0.4009995605864644 0.8192984229746454 0.412616172126107 1.0 0.7046705408264041 17 Q4J6C6,P56545,Q13277,O95295,P35080,P20339,O00161,Q00535 8 +Camera type eye morphogenesis 0.5429290108682792 0.8161847688007988 0.4143944668177073 1.0 0.7067654298280706 8 Q15555,Q16706 2 +Folic acid containing compound metabolic process 0.4334053294747008 0.8151338351418163 0.4149957060008156 1.0 0.7073544087409044 14 Q8IYS1,P41440,P00374 3 +Neural precursor cell proliferation 0.36755547460499 0.8147738350371662 0.415201780570289 1.0 0.7073544087409044 26 O15031,Q96N67,P61586,O95456,Q13418 5 +Detection of stimulus 0.4512234567203887 0.8144409128068875 0.4153924087788425 1.0 0.7073544087409044 13 P04439,Q9UNS1,Q15555,Q13432,Q13586 5 +Positive regulation of cellular amide metabolic process 0.3126731433358912 0.8142307995328973 0.4155127443165818 1.0 0.7073544087409044 57 O15031,P51114,P62487,P67809,P42345,Q14011,Q13217,P16989,O15371,Q567V2,O15514,Q13492,P61586,P98179 14 +Positive regulation of phosphorus metabolic process 0.2939585746911387 0.8135307580266332 0.415913818861418 1.0 0.7076086347427072 112 Q8NDZ4,Q9UHD1,Q13432,Q96HY6,Q96M27,Q99570,P41440,Q9ULW0,Q00535,Q13418,Q9H7B4,P31751,P23396,Q92797,P50750,P61586,Q96A49,Q05639,P14635,Q96N67,Q9NQS7,Q9UJZ1,O95429,P51114,P42345,P33121,Q9HAW4,Q9BZF1,P54652,P49959,P54619,Q99653 32 +Transition metal ion homeostasis 0.3673649135754785 0.8134214753735644 0.4159764507546057 1.0 0.7076086347427072 26 P09601,Q9Y487,O43819 3 +Tyrosine phosphorylation of stat protein 0.5692956832197378 0.8071875542733659 0.4195584350267345 1.0 0.7120804967083185 4 P30153,P22059,P07948 3 +Regulation of stress granule assembly 0.5692561505758468 0.8070328652267367 0.4196475486438866 1.0 0.7120804967083185 4 Q9UN86 1 +Cellular response to vitamin d 0.5679772190295622 0.8057847489904458 0.4203669732434347 1.0 0.7125882060326655 5 O15164,Q15648,Q8TB36 3 +Retrograde transport vesicle recycling within golgi 0.5678168205884659 0.8051523033690194 0.4207317965376962 1.0 0.7127404190781913 5 Q9UP83,Q14746 2 +Positive regulation of cysteine type endopeptidase activity 0.3604016642219032 0.8035749486822524 0.4216424957442659 1.0 0.7131587810886206 28 Q13794,Q92688,Q07812,Q9P0J0,Q96F07,O95831,P61586 7 +Axon development 0.3107855451234723 0.8032381468281683 0.4218371008472883 1.0 0.7131587810886206 59 O15031,P00374,P07196,Q12955,Q96N67,Q9UQB8,O94813,P41440,Q9P265 9 +Neutrophil mediated immunity 0.5682420848220321 0.8030669246898388 0.4219360536916514 1.0 0.7131587810886206 4 O00186,P51809 2 +Multicellular organismal response to stress 0.5672686459585181 0.8029916354106196 0.4219795692433878 1.0 0.7131587810886206 5 P42345 1 +Proteasomal protein catabolic process 0.2800350683135366 0.802984149722896 0.4219838959504693 1.0 0.7131587810886206 150 Q96HY6,Q9NYU2,Q9UJX3,Q9H1A4,Q9BZK7,Q9UBV2,P49721,Q9Y5A7,Q92575,P28074,Q96J02,Q14145,Q16763,Q9Y679,Q9Y5K6,Q96PU5,Q8IXB1,Q13794,Q13616,O43791,P28070,P46379 22 +Spermatid differentiation 0.3904482616417485 0.8023110757605417 0.4223730371539136 1.0 0.7131587810886206 19 P54652,Q96SI9,A0AVF1,Q07812,Q96KQ7,Q9Y385 6 +Gland development 0.3073356978242528 0.8013849475564753 0.4229088265639116 1.0 0.7131587810886206 65 Q13505,P11310,P09601,Q05086 4 +Cellular response to reactive oxygen species 0.3629697461625245 0.8011672911270832 0.423034804243426 1.0 0.7131587810886206 27 Q99720 1 +Positive regulation of establishment of protein localization to mitochondrion 0.4661139085255396 0.8011417113997324 0.4230496110135546 1.0 0.7131587810886206 12 P55786 1 +Neuron apoptotic process 0.3304842802710525 0.8008811692204149 0.4232004425780711 1.0 0.7131587810886206 43 Q99720,P31751,P07196,Q07812,P78362,O95831,P09601,P61586 8 +Positive regulation of transporter activity 0.3901522444865808 0.8004453645192336 0.4234528064597715 1.0 0.7132891607103068 19 Q9UHD1,P28161,Q03164,P54652,Q12955,Q13586,Q99653,P78417 8 +Pyrimidine nucleoside triphosphate biosynthetic process 0.5525883704896977 0.798892413072172 0.4243527985763853 1.0 0.7139265721677807 7 O75414 1 +Cellular process involved in reproduction in multicellular organism 0.3301627103991366 0.7980734195068072 0.4248278853081464 1.0 0.714103236233006 43 Q8NB78,P42345,P54652,Q96SI9,A0AVF1,Q01085,Q07812,Q96KQ7,O94813,Q9Y385 10 +Nuclear transcribed mrna catabolic process 0.3119028900347315 0.7974257925125507 0.4252037846232404 1.0 0.7145475981890026 52 Q96B26,P62487,P60228,Q9NQT5,Q99729,P67809,Q15024,Q96C86,Q13868,O15514,O95453,Q969T7,Q6PGP7 13 +Negative regulation of ion transmembrane transport 0.4298346884641048 0.795543796417815 0.4262972452409532 1.0 0.715910934421675 14 Q96PU5,Q12955 2 +3 utr mediated mrna destabilization 0.5639281999652735 0.7944861615578509 0.4269124619952609 1.0 0.716591055719976 6 Q92900,Q92945,Q9HCE1 3 +Myeloid cell activation involved in immune response 0.5377313271919858 0.7940164388310468 0.4271858613755706 1.0 0.7167304242664674 8 P09601 1 +Dicarboxylic acid transport 0.3930794115210594 0.7933226010614174 0.4275898921940131 1.0 0.7169356859541092 18 Q15758,P41440,O60831,Q8TDW0 4 +Attachment of spindle microtubules to kinetochore 0.4185979618933709 0.7909939572781925 0.4289475177028159 1.0 0.7185768301266315 15 Q96DB5,P14635 2 +Dicarboxylic acid metabolic process 0.3291337722651444 0.789107714870239 0.4300490532253762 1.0 0.7191678780799778 43 Q8TD30,Q9P2R7,Q9H9P8,P48735,P00374,O75874,P41440,Q02218,P30520 9 +Antigen processing and presentation of exogenous peptide antigen 0.5632009895171585 0.7869964492563774 0.4312839447348153 1.0 0.7199649545957584 5 P50570,Q03518 2 +Nadp metabolic process 0.4068342495176576 0.7859008100682635 0.4319255999491513 1.0 0.7204045592376621 16 O75874,Q13423,P48735 3 +Positive regulation of axonogenesis 0.4963932393267795 0.7856666553714511 0.4320628030894626 1.0 0.7204045592376621 10 O15031,O94813 2 +Gtp metabolic process 0.4629470699367962 0.7852706154026011 0.4322949204931086 1.0 0.7206040230754238 12 O60313,P61586,O75414 3 +Camp mediated signaling 0.563485051818109 0.7845162536793883 0.4327372485329706 1.0 0.720778682813887 4 P63096,P49427 2 +Nervous system process 0.3052191534171651 0.7831581322169284 0.4335342575492351 1.0 0.7214366381995377 87 P49419,P07196,Q15555,Q13432,Q12955,P62072,Q9UQB8,Q13614,Q9H6K4,P78417,Q05086,Q9BRK0 12 +Multicellular organismal movement 0.5487386930345914 0.7831196522069728 0.4335568517725847 1.0 0.7214366381995377 7 P18887,P42345,P78417 3 +Pyrimidine ribonucleotide biosynthetic process 0.5484648228924223 0.7820001834484429 0.4342144657795481 1.0 0.7216833602497407 7 O75414 1 +Calcineurin mediated signaling 0.5606422753936652 0.7814810372060208 0.4345196254266703 1.0 0.7216833602497407 6 Q99653,P42345 2 +Regulation of calcineurin mediated signaling 0.5606422753936652 0.7814810372060208 0.4345196254266703 1.0 0.7216833602497407 6 Q99653,P42345 2 +Regulation of calcium mediated signaling 0.5606422753936652 0.7814810372060208 0.4345196254266703 1.0 0.7216833602497407 6 Q99653,P42345 2 +Inositol phosphate mediated signaling 0.5606422753936652 0.7814810372060208 0.4345196254266703 1.0 0.7216833602497407 6 Q99653,P42345 2 +Negative regulation of cysteine type endopeptidase activity 0.3791407606175188 0.7803136574407065 0.4352062758319261 1.0 0.7223005155010235 21 Q15392 1 +Recombinational repair 0.3084639206624518 0.7798236550210632 0.4354946807385029 1.0 0.722376405332042 59 Q68CP9,Q9UBU8,Q9UNS1,P49736,P18887,Q9NRR5,Q96T76,P25205,P46063,P49959,Q9BRT9,P35637,Q96B01,Q9NY27,O14757,Q96SB8 16 +Golgi to plasma membrane protein transport 0.4269530009808396 0.7798133790102242 0.4355007301580309 1.0 0.722376405332042 14 Q8N2H4,Q12955,Q9BZG1 3 +Regulation of er associated ubiquitin dependent protein catabolic process 0.49929128392227 0.7794988794036496 0.4356858974377127 1.0 0.7224317405467988 3 P51572 1 +Sarcoplasmic reticulum calcium ion transport 0.5597891754096425 0.7781122267777946 0.4365028552939858 1.0 0.7229155354222526 6 P78417 1 +Cell junction disassembly 0.5612646957145089 0.775889016658509 0.437814518210053 1.0 0.7241690305822948 4 Q15555 1 +Regulation of establishment of protein localization to mitochondrion 0.3936814174489689 0.7750107818685792 0.4383332885777444 1.0 0.7246356249365241 17 P55786,O95429 2 +Cellular response to lipid 0.3038575821185008 0.7740317715692888 0.4389120030346851 1.0 0.7254051319505143 90 Q9H7B4,Q9NUQ7,P50416,O75376,Q86X55,O43823,P10620,Q96HY6,Q13547,P61586,O95831,P11802,Q9P0J0,Q86U42,Q05086 15 +Histone methylation 0.3090325297013204 0.771200794546854 0.4405879233259517 1.0 0.7274242878417647 54 Q03164,Q9H7B4,Q15047,Q12824 4 +Kinetochore assembly 0.4972871974644178 0.7707975465123874 0.4408269417475772 1.0 0.7276313807871629 3 P50748 1 +Negative regulation of erk1 and erk2 cascade 0.4427777789676679 0.7702979857901616 0.4411231509204569 1.0 0.727760597133234 13 P57105,P07948,P18031,Q99956,Q96P70,P41240 6 +Cartilage development 0.4766814148093159 0.7701728517463957 0.4411973656661763 1.0 0.727760597133234 11 Q9C0E8 1 +Regulation of neuronal synaptic plasticity 0.5572238916185752 0.7680015805413418 0.4424862458913519 1.0 0.7294304918116316 6 Q9UBB6 1 +Cytoplasmic microtubule organization 0.4141846412716599 0.7661950123930309 0.4435602756328876 1.0 0.7308202762424185 15 Q9UHD1,Q03001,Q14203,Q96CW5,Q99653,P61586 6 +Protein localization to membrane raft 0.5576599174089676 0.765318941325178 0.4440816477252596 1.0 0.7313077211640135 5 P41440 1 +Negative regulation of vascular associated smooth muscle cell proliferation 0.5561132619256037 0.7636334162038896 0.4450857298787896 1.0 0.73202033006509 6 P09601,P61586 2 +Cellular protein catabolic process 0.2637585154624123 0.7620785819741958 0.4460131050339344 1.0 0.7327906384356501 222 Q9H7D7,Q96T88,A4D1P6,Q96HY6,Q6IQ22,Q9NYU2,Q9UL46,Q9BRG1,Q8WU17,Q9UJX3,Q9H1A4,Q96RL7,Q9BZK7,Q9UHG3,Q9UBV2,Q99436,P49721,Q9Y385,Q9NRR5,Q96K76,Q16740,P60520,Q05086,Q9H2J4,Q9Y5A7,Q92575,Q96DX4,P28074,Q13217,Q96J02,Q9UG56,Q14145,Q16763,Q9Y679,Q9Y5K6,Q96PU5,Q8IXB1,Q13794,Q13616,O43791,P20618,O95816,Q9P275,P28070,P46379,Q5T4S7 46 +Regulation of circadian rhythm 0.3622303686323441 0.7607295613128332 0.4468186143011539 1.0 0.7327906384356501 25 Q9Y2K7 1 +Regulation of macroautophagy 0.3163533914009428 0.7604999830992548 0.4469557793589307 1.0 0.7327906384356501 48 Q9Y5K8,Q8TBX8,P42345,Q9Y371,Q96KQ7,Q9P275,Q9Y487,O75396,Q99570,Q9NRR5,P09601,Q93050,O15269 13 +Positive regulation of cell cycle g2 m phase transition 0.4579527879709739 0.7603918926649292 0.4470203679551785 1.0 0.7327906384356501 12 P14635,P11802 2 +Regulation of neutrophil migration 0.5297740874156053 0.760342484422167 0.4470498932333742 1.0 0.7327906384356501 8 O94813,P63000,Q00013 3 +Cardiac muscle cell proliferation 0.5562949289716055 0.7599995293132461 0.4472548662258142 1.0 0.7327906384356501 5 Q8NDZ4 1 +Negative regulation of neuron death 0.3394164960797967 0.7588265640055952 0.447956312849517 1.0 0.7327906384356501 35 P07196,Q07812,Q9UMX5,P51858,P09601,P61586 6 +Cellular respiration 0.2931011268934091 0.7582623056077936 0.4482939683379348 1.0 0.7331350164248007 108 P13073,P03886,Q9BSK2,P00846,Q16718,Q02218,O43676,P48735,P08574,P61586,Q9P2R7,P14635,O95168,Q13423,O75964,O75874,O43819,O96000,P56134,Q15070 20 +Steroid hormone mediated signaling pathway 0.3366531792482286 0.7574459972362075 0.4487827077110391 1.0 0.7334790449230925 36 Q9NUQ7,O75376,Q86X55,Q96HY6,P61586,Q05086 6 +Eye morphogenesis 0.4736601425726253 0.7557577264665112 0.4497944665082678 1.0 0.7341104082680162 11 Q15555,Q16706 2 +Monoubiquitinated protein deubiquitination 0.5093109992860462 0.7546384138444265 0.4504659682487824 1.0 0.7350191015287061 9 Q96K76 1 +Establishment of protein localization to endoplasmic reticulum 0.3750176512533256 0.7536379780895351 0.4510666332393038 1.0 0.7354372238561925 21 P61619,P09132,P61009,P46379,Q9Y5M8,O43681 6 +Mammary gland development 0.3710324128319309 0.7511500549160854 0.4525623543711403 1.0 0.7371361540800483 22 P31751,Q13505,Q07812,Q9NQC3,P35670 5 +Synaptic vesicle exocytosis 0.4113869649567786 0.750574935867496 0.4529085099965109 1.0 0.7373303324250922 15 Q4J6C6,Q13277,O95295,P35080,P20339,O00161,Q00535 7 +Regulation of dna templated transcription in response to stress 0.4559680093008489 0.7505586147148687 0.4529183356373303 1.0 0.7373303324250922 12 P55061,Q9NYF8,P51812,O14757,P09601 5 +Somatic diversification of immunoglobulins 0.3859156835124798 0.7494798632551862 0.4535680311377534 1.0 0.737870865690286 18 Q9UQ84 1 +Regulation of synapse structure or activity 0.3448509170571645 0.7494335747985401 0.4535959208692393 1.0 0.737870865690286 32 Q9UQB8,Q05086 2 +Neuroblast proliferation 0.4883078955303491 0.7484848073670275 0.4541677855536115 1.0 0.7383712858255738 10 O15031 1 +Cellular component morphogenesis 0.283716059951934 0.7483495661314671 0.4542493345985929 1.0 0.7383712858255738 117 O15031,Q96PU5,Q9P265,Q9Y4F1,P07196,Q12955,Q96N67,Q9UQB8,Q9Y2J2,Q96F07,Q13614,O94813,P41440,P61586,Q05086,O15228 16 +Vascular process in circulatory system 0.3495084476591013 0.7468840139495436 0.4551335763873498 1.0 0.7394333477903533 29 P30825,Q16625,Q9HB40,Q8WWI5,O94813,Q15758,P41440 7 +Negative regulation of defense response to virus 0.5526807919485999 0.7459561158776881 0.4556939249734251 1.0 0.739883325671817 5 O43657 1 +Regulation of neutrophil chemotaxis 0.5395725341218905 0.7458516407998182 0.4557570407588183 1.0 0.739883325671817 7 O94813,P63000,Q00013 3 +Positive regulation of translation 0.3058578179401493 0.744006507903818 0.4568725379607814 1.0 0.7413185101764859 56 O15031,P51114,P62487,P42345,Q14011,Q13217,P16989,O15371,Q567V2,O15514,P61586,P98179 12 +Cytoskeleton dependent cytokinesis 0.3284247666039195 0.7423199674807516 0.4578934967132437 1.0 0.7427869688389566 40 Q6DKK2,Q14141,Q13432,Q12955,Q9NQS7,Q9BXF3,O75935,P61586 8 +Mitotic g2 dna damage checkpoint signaling 0.4541449793628861 0.741554759943716 0.4583571421883117 1.0 0.7432853651266564 12 Q9HAW4,Q6NUQ1,O14757,P49959 4 +Regulation of calcium ion dependent exocytosis 0.5515105535828069 0.7414219979710304 0.458437610541959 1.0 0.7432853651266564 5 O00186,Q00535 2 +Steroid hormone biosynthetic process 0.5383831422319107 0.7410471489758639 0.4586648530043198 1.0 0.7432853651266564 7 Q53GQ0 1 +Hormone biosynthetic process 0.5056028138543 0.7384296664089799 0.460253392544147 1.0 0.7449352549144532 9 Q53GQ0 1 +Phosphatidylinositol 3 kinase signaling 0.5234704262106694 0.7339118357469102 0.4630024730851581 1.0 0.7474782869414119 8 Q8NDZ4,Q05086 2 +Positive regulation of muscle contraction 0.5477024321761604 0.7307423266861375 0.4649365567997106 1.0 0.7492255077564475 6 P61586,P78417 2 +Actin filament severing 0.5475515115493907 0.7301553076000448 0.4652952574643194 1.0 0.7492255077564475 6 P60981,P35579,Q9Y281,Q9BPX3 4 +Sterol biosynthetic process 0.3523907410645723 0.7263436180273789 0.4676281461319913 1.0 0.7519866475975406 27 P56937,Q15392,Q14739,Q9UHQ9 4 +Autophagosome organization 0.3671149463141268 0.7256427856933142 0.4680577846719576 1.0 0.7522273378345611 22 Q8TBX8,P50851,Q9Y371,P62820,Q96KQ7,O95140,O75396,P60520 8 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.5024174220205525 0.7245763346707497 0.4687119815226337 1.0 0.7527121969501107 9 O43657 1 +Peptidyl lysine hydroxylation 0.5458991996220885 0.7237360764834099 0.4692277803081168 1.0 0.7533115939148215 6 Q02809,Q96AY3,O00469,Q9H267 4 +Protein n linked glycosylation 0.3629725907827681 0.7235852265772399 0.4693204138798084 1.0 0.7533115939148215 23 P26572,Q13724,Q96AA3,Q9HC07,Q9H553,Q9NYU2,Q9BT22 7 +Protein localization to cilium 0.5012095741474031 0.7193409165712955 0.4719308911569282 1.0 0.7564396299521964 9 Q9Y5K8,A0AVF1,Q10713 3 +Cyclic nucleotide mediated signaling 0.5457670127240228 0.7192649157382428 0.4719777085418246 1.0 0.7564396299521964 5 P63096,P49427 2 +Regulation of double strand break repair 0.3342853669954151 0.7189166347233086 0.4721922863772134 1.0 0.7565942437549849 35 Q68CP9,Q9UBU8,Q9UNS1,Q96T76,Q9NRR5,P35637,Q96B01,Q9NY27,O14757,O96028 10 +Mrna catabolic process 0.29617449739764 0.7186056711353246 0.4723839181485219 1.0 0.7567120229205879 98 Q9Y4Y9,Q92804,P60228,Q14011,Q7L8L6,Q969T7,P62487,P16989,Q13868,Q92945,P62312,Q6PGP7,Q6P6C2,Q9NQT5,P67809,Q99729,Q15024,P98175,P51114,Q96B26,Q9HCE1,O00178,O15514,P35637 24 +Deoxyribonucleoside metabolic process 0.546270305384262 0.7181974480604516 0.472635551235061 1.0 0.7569258353029503 4 P04183 1 +Regulation of ubiquitin protein ligase activity 0.4493122539124224 0.7178213936714554 0.4728674204919194 1.0 0.757107896943573 12 P62841,Q16763 2 +Regulation of leukocyte degranulation 0.5448855601308119 0.7158790949123566 0.4740660078161953 1.0 0.7583055173803898 5 P09601 1 +Trna wobble base modification 0.5448274404800819 0.7156559865243133 0.4742037942297861 1.0 0.7583055173803898 5 O75648,O95163,Q969Y2 3 +Monosaccharide biosynthetic process 0.3555490430887866 0.7151301408223965 0.4745286310131977 1.0 0.7584255458606357 25 P11310 1 +Lens development in camera type eye 0.5445451949460618 0.7145727559049506 0.4748730842711217 1.0 0.7584255458606357 5 Q15648 1 +Regulation of actin filament organization 0.3027805446599077 0.7142824821162348 0.4750525222830526 1.0 0.7585210512824614 56 O95429,Q9UEY8,Q9Y613,Q9UQB8,P35611,Q08722,P14373,O94813,Q96F07,P61586 10 +Branching morphogenesis of an epithelial tube 0.448377028962404 0.713251988090853 0.4756898413340855 1.0 0.7589848040531527 12 Q13418,Q14344,P31277,O94813 4 +Muscle structure development 0.2988972694448046 0.71270031062186 0.4760312242359017 1.0 0.7591376705141116 87 P11310,P46939,Q9H7B4,P67809,P51114,P42345,P85037,P16989,Q9NR56,Q9Y5Q8,Q13547,P24468,P50750,Q9BYT8,P41440,Q9NQ29,P61586 17 +Regulation of neurogenesis 0.3089972146647201 0.7108555373594722 0.4771737610295581 1.0 0.7603918191928729 49 O15031,P07196,Q96N67,Q9NQC3,Q9UQB8,Q16706,O94813,P55209,Q9P265 9 +Oxidative phosphorylation 0.295562238318624 0.710529002383224 0.4773761525338542 1.0 0.7605251512389629 69 O43676,P13073,O75964,P03886,P14635,O95168,P56134,Q9BSK2,O96000,P08574,P00846,Q16718,P61586 13 +Negative regulation of protein localization to cell surface 0.5441448697622366 0.7101061174565728 0.4776383330414224 1.0 0.7606199501791888 4 Q96PU5 1 +Ossification 0.3025175831727201 0.7099501590145361 0.4777350441471277 1.0 0.7606199501791888 55 Q86V81,Q9UHQ4,Q9H6W3,P62841,Q13418 5 +Protein deglycosylation 0.5176844241251928 0.7098585384488868 0.4777918638028497 1.0 0.7606199501791888 8 O60476,O60502,Q16706,Q9NYU2 4 +Response to tumor necrosis factor 0.3472532307183648 0.7095278926016062 0.4779969487500295 1.0 0.7607573797994259 28 Q9Y5A7,O95429,Q96RT1,P78318,P16989,Q13418 6 +Presynaptic endocytosis 0.4792830380973693 0.7075148638046015 0.4792465790451417 1.0 0.7615880572267641 10 O14976,Q96CW1,Q13492,P50570 4 +Maternal process involved in female pregnancy 0.5299317703859686 0.7071313040366302 0.47948488398873 1.0 0.7616117448132419 7 Q8IZL8,P24468 2 +Regulation of translational termination 0.5430758892078067 0.7060452718819362 0.4801599842579518 1.0 0.7623060369656603 4 P63241 1 +Regulation of mononuclear cell migration 0.4032246210393703 0.7054839422553295 0.4805091215050825 1.0 0.7626153357100914 15 P61586,Q08722,O94813 3 +Positive regulation of cellular component biogenesis 0.2901698462018461 0.7045528227837263 0.4810885665141327 1.0 0.7628553898344802 106 Q13641,O95429,Q8TBX8,Q16625,Q71SY5,P50570,Q9Y613,P42345,Q15555,Q07812,Q9Y371,Q9HCM4,Q9UQB8,Q15047,Q08722,P41440,P61586 17 +5s class rrna transcription by rna polymerase iii 0.5418506273209279 0.7042521296782783 0.4812757720962475 1.0 0.7628553898344802 5 Q9Y5Q8 1 +Negative regulation of endocytosis 0.49770897583747 0.7042237669129727 0.4812934322395132 1.0 0.7628553898344802 9 Q13432 1 +Negative regulation of receptor mediated endocytosis 0.49770897583747 0.7042237669129727 0.4812934322395132 1.0 0.7628553898344802 9 Q13432 1 +Modification of synaptic structure 0.5158503620478199 0.7022776516708311 0.4825060276012056 1.0 0.7635705565250305 8 Q9UQB8,P61586,O95793 3 +Regulation of nervous system process 0.515108677603518 0.6992181317918411 0.4844157208879929 1.0 0.7658359101699117 8 Q9UQB8 1 +Calcium ion transport 0.3011722289704035 0.698902754044907 0.4846128062630515 1.0 0.7659584596400463 56 P61619,P98194,P54652,Q9UM00,Q13586,Q07812,Q9HC07,Q13555,P14373,Q9UJZ1,P61586,P78417 12 +Posttranslational protein targeting to endoplasmic reticulum membrane 0.5277536299814942 0.6984565542436287 0.4848917189687842 1.0 0.7662102495594553 7 P61619 1 +Amyloid beta clearance 0.4960460488032112 0.6970725180661101 0.4857574118526577 1.0 0.7671996992919441 9 Q16850,Q13547,Q13492,P20339,Q15907 5 +Myeloid leukocyte mediated immunity 0.4112214427175367 0.6953455724201069 0.486838760913012 1.0 0.76777181250831 14 P09601 1 +Phosphatidic acid metabolic process 0.5139414710803651 0.6944105634821726 0.4874247709705059 1.0 0.7683176877059699 8 Q9NPH0 1 +Positive regulation of double strand break repair 0.3688062201439119 0.6939478536239119 0.4877149118097255 1.0 0.7684265714813889 20 Q68CP9,Q9UBU8,Q9UNS1,Q96T76,Q96B01 5 +Immunoglobulin production 0.3583516944593665 0.6933365442581356 0.4880983743920717 1.0 0.7684265714813889 23 Q9UQ84 1 +Lung alveolus development 0.5393175903148633 0.6918154195820766 0.4890532519403094 1.0 0.7684265714813889 4 O60476 1 +Response to dsrna 0.3902634502595389 0.6909425704707118 0.4896016321584526 1.0 0.7689110212324216 16 P41440,Q13794 2 +Regulation of nitric oxide metabolic process 0.4945432144365413 0.6906267941836178 0.4898001047310267 1.0 0.7690341840458229 9 Q92945,Q08722,P50570 3 +Cellular response to corticosteroid stimulus 0.4596841932115613 0.6899870784590547 0.490202313267905 1.0 0.7694770935540797 11 Q9H7B4 1 +Histone modification 0.2718575113606094 0.6868955239090357 0.4921485678146067 1.0 0.7718024856435847 152 Q8NB78,Q9H7B4,Q9UBU8,Q96T88,Q03164,Q86X55,Q9BZK7,Q15047,Q9H6W3,Q9Y2K7,P50750,Q86UY6,Q9UKN8,Q12824 14 +Peptide catabolic process 0.4743958109551067 0.6855852474238808 0.4929746870594713 1.0 0.7723807422634829 10 P55786 1 +Post golgi vesicle mediated transport 0.3169759769494363 0.6854884385325102 0.4930357537838523 1.0 0.7723807422634829 43 Q4J6C6,Q567U6,Q7Z3U7,O14976,O15127,Q92538,O15126,P50570,O95782,Q96RL7,Q12955,Q9BZG1,P36405,O00161,P98194,P61026,O00471,P41240,Q8N2H4,Q9NV70 20 +Insulin receptor signaling pathway 0.3606961558193237 0.6843941608018749 0.4937263022406397 1.0 0.77292538908933 22 Q8TBX8,Q9HCD5,P62993,P31751,Q9BZF1,Q13131,Q9UQB8,P43490,Q86YS7,P11802,O14654 11 +Receptor mediated endocytosis 0.3094154386472437 0.682727470068889 0.4947790682077013 1.0 0.7743842440602332 47 Q9Y5K6,P63010,P50570,P20645,O95782,Q13432,Q96D71,Q13492,Q13614,O14976,P41440 11 +Methionine metabolic process 0.5353904764765219 0.6796678158028722 0.4967148189825003 1.0 0.7754583724177211 5 Q99707,Q13126 2 +Methionine biosynthetic process 0.5353904764765219 0.6796678158028722 0.4967148189825003 1.0 0.7754583724177211 5 Q99707,Q13126 2 +Sulfur amino acid biosynthetic process 0.5353904764765219 0.6796678158028722 0.4967148189825003 1.0 0.7754583724177211 5 Q99707,Q13126 2 +Negative regulation of reproductive process 0.5358786498191155 0.678861020994484 0.4972259254546838 1.0 0.7754583724177211 4 P27797,P35579 2 +Cell migration involved in sprouting angiogenesis 0.5227989369989665 0.6788308390514451 0.4972450512235664 1.0 0.7754583724177211 7 P09601,P61586,O94813 3 +Neuron projection arborization 0.5356441789815454 0.6779801427509039 0.4977842837154909 1.0 0.7754583724177211 4 Q13641 1 +Protein k29 linked ubiquitination 0.475564039865738 0.6779635958072647 0.4977947754434155 1.0 0.7754583724177211 3 Q96J02 1 +Pteridine containing compound biosynthetic process 0.5224016442137671 0.6772637643535249 0.4982386171633679 1.0 0.7754583724177211 7 P00374 1 +Cerebral cortex radially oriented cell migration 0.5097508737169123 0.6772249913635442 0.4982632136236926 1.0 0.7754583724177211 8 Q8WXH0,Q9NQC3,O94901,Q00535,P43034 5 +Telencephalon glial cell migration 0.5097508737169123 0.6772249913635442 0.4982632136236926 1.0 0.7754583724177211 8 Q8WXH0,Q9NQC3,O94901,Q00535,P43034 5 +Organ growth 0.3660150484115987 0.6767113871555169 0.4985890901716203 1.0 0.7754583724177211 20 Q8NDZ4,Q99956,P16989,Q96KQ7,Q05086 5 +Defense response to symbiont 0.299149134568538 0.6766741637256295 0.4986127124552908 1.0 0.7754583724177211 52 Q8IZ81,Q13794,O95801,Q9NUD5,Q13217,Q96J02,O14802,P14373,Q7Z7L1,Q9HCL2,O43657 11 +Pons development 0.4746474749972111 0.6741128037284211 0.5002395999649225 1.0 0.7760509409388381 3 O95487 1 +Meiotic cell cycle 0.302970458404337 0.6739764014240709 0.5003263169024978 1.0 0.7760509409388381 50 Q9BXW9,P54652,O60566,Q96KQ7,Q9NQS7,Q9UQ84,P24941,Q96B01,Q96CW5,P46379,P49959,Q08J23,O94901,Q15021 14 +Negative regulation of smooth muscle cell proliferation 0.5084970787927334 0.6721065381319407 0.5015158745105031 1.0 0.7773314038505401 8 P09601,P61586 2 +Response to fatty acid 0.4398024418550702 0.6717348844326619 0.5017524890562459 1.0 0.7774799888867052 12 P50416,P33121,O15228 3 +Glycerolipid biosynthetic process 0.3046050321335617 0.671526008553701 0.5018854965024309 1.0 0.7774799888867052 49 Q96BW9,Q8TBX8,P33121,P48651,Q8WTV0,Q9BVG9,Q9NPH0,Q8WWI5,Q9UG56,Q10713,O60762,Q13614,P42356,Q99570,Q7L5N7,Q9HCL2,O15228 17 +Positive regulation of peptidase activity 0.3220410270632552 0.6713841484289527 0.5019758404675949 1.0 0.7774799888867052 38 Q13794,Q92688,P23396,Q07812,Q9P0J0,Q96HY6,Q96F07,Q9UL46,O95831,P61586 10 +Positive regulation of lipid storage 0.5332652041998104 0.6690600747213212 0.5034571569955903 1.0 0.7786648655737397 4 O60664,Q8WTV0 2 +Negative regulation of intracellular estrogen receptor signaling pathway 0.5326192794547272 0.6666436974025033 0.5049997501774535 1.0 0.7794511546541345 4 Q92600,P38398,A5YKK6 3 +Regulation of gene expression epigenetic 0.3091592434664774 0.6665280500319601 0.5050736408007044 1.0 0.7794511546541345 46 Q15047,Q8NB78 2 +Positive regulation of dna recombination 0.3501903002422774 0.6662056233416508 0.5052796790974317 1.0 0.779581316064101 24 Q68CP9,Q9UBU8,Q9NQT5,Q9UNS1,Q96T76,Q96B01,O96028 7 +Negative regulation of insulin secretion involved in cellular response to glucose stimulus 0.4135582225105361 0.6618037047734913 0.5080970315098976 1.0 0.7829610471365013 2 Q8N5M9 1 +Negative regulation of protein polyubiquitination 0.4715314400561179 0.6610656175189614 0.5085702337082394 1.0 0.7829610471365013 3 O95071 1 +Negative regulation of protein k63 linked ubiquitination 0.4715314400561179 0.6610656175189614 0.5085702337082394 1.0 0.7829610471365013 3 O95071 1 +Histone h2a k63 linked ubiquitination 0.4715314400561179 0.6610656175189614 0.5085702337082394 1.0 0.7829610471365013 3 O95071 1 +Protein catabolic process 0.2458694819850512 0.656885570171438 0.5112544972184445 1.0 0.7856498769280263 253 Q9H7D7,Q96T88,A4D1P6,Q96HY6,Q6IQ22,Q9NYU2,Q9UL46,Q9BRG1,O60502,Q8WU17,Q9UJX3,Q9H1A4,Q96RL7,Q9BZK7,Q9UHG3,Q9UBV2,Q99436,O75396,P49721,Q9Y385,Q9NRR5,Q96K76,Q16740,P60520,Q05086,Q9H2J4,Q9Y5A7,Q92575,Q96DX4,P28074,Q05639,Q13217,Q96J02,Q9UG56,Q14145,Q16763,Q9Y679,Q5T4S7,Q9Y5K6,Q96PU5,Q8IXB1,P42345,Q13794,Q13616,O43791,P20618,O95816,O43847,Q9P275,P28070,P46379,Q9P0J0 52 +Neurotransmitter transport 0.3525959632250167 0.6562106593276886 0.5116885914013591 1.0 0.7860616586371958 23 O00186,Q4J6C6,P56545,Q13277,O95295,P35080,P41440,P20339,O00161,Q00535 10 +Regulation of camp dependent protein kinase activity 0.529186001627483 0.6538405804677178 0.5132145189613315 1.0 0.7878796424618164 4 Q9Y4G8,P10644 2 +Positive regulation of dna binding transcription factor activity 0.3299682897581782 0.6537364662640078 0.5132816050929083 1.0 0.7878796424618164 33 P41440,Q12824,P14373 3 +Cellular response to oxygen levels 0.3256894329133893 0.6536086412058288 0.5133639755909494 1.0 0.7878796424618164 35 O95831,P55786,P09601,Q9Y487 4 +Antigen processing and presentation of peptide antigen via mhc class i 0.4667575193627513 0.6517049750788659 0.5145915125305276 1.0 0.7893853518368198 10 Q03519,Q9NZ08,Q03518 3 +Animal organ regeneration 0.3830819971251715 0.6508650448499211 0.5151336075918391 1.0 0.7900277448487721 16 P50416,P09601 2 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.4850086028212086 0.6501285068570344 0.5156092167529818 1.0 0.7902101238664361 9 Q9HBM6,Q96K76 2 +Muscle cell apoptotic process 0.4190602237123607 0.6497849548928084 0.5158311385707011 1.0 0.7902101238664361 13 Q8NDZ4,P09601,P98175 3 +Vascular associated smooth muscle cell proliferation 0.4507422439937689 0.6487840259246852 0.516477983936674 1.0 0.7902101238664361 11 P09601,P61586 2 +Camera type eye development 0.3384786680997041 0.6487715118135331 0.5164860737790771 1.0 0.7902101238664361 28 Q15293,Q15555,Q15648,Q07812,P20020,O95140,Q13547,P83731,Q16706 9 +Positive regulation of protein metabolic process 0.2298679452501111 0.648295447942951 0.516793877660565 1.0 0.7904336674042359 300 O15031,Q8NDZ4,Q96T88,Q9UHD1,Q03164,Q14011,Q13432,O43823,Q96HY6,Q96M27,Q9UL46,P41440,Q13418,Q9P265,Q8WU17,Q6PD62,Q9H7B4,P62487,P31751,P23396,P16989,O75396,P50750,P61586,P98179,Q05086,Q96A49,Q9Y5A7,Q92688,P14635,Q13217,Q07812,Q96N67,Q96J02,O15371,Q96P70,Q96F07,Q14145,O95831,Q16763,Q96PU5,O95429,P51114,P42345,P33121,Q13794,P54652,P49959,Q567V2,O15514,P62820,O95816,O43847,P46379,Q99653,Q9P0J0,Q12824 57 +Somatic diversification of immune receptors 0.3466128430758885 0.6429448501354753 0.5202598858624057 1.0 0.7946554193692349 24 Q9UQ84 1 +Artery morphogenesis 0.5249078034227379 0.6402875013447692 0.521985704907082 1.0 0.7962838190899498 5 Q96AY3 1 +Regulation of toll like receptor signaling pathway 0.4824575908390135 0.6394150909534726 0.5225529342651118 1.0 0.7968279211859811 9 Q9NPR9,P41440 2 +Cell part morphogenesis 0.2857908174137119 0.6384587511657085 0.5231750970102778 1.0 0.7970556095198351 104 O15031,Q96PU5,Q9Y4F1,P07196,Q12955,Q96N67,Q9UQB8,Q9Y2J2,Q96F07,O94813,P41440,P61586,Q05086,Q9P265 14 +Response to acidic ph 0.5246510728285299 0.637037188897253 0.5241006201144067 1.0 0.798098519476735 4 Q99653,Q9UHD1 2 +Peptidyl amino acid modification 0.2531292629532374 0.6369168304741799 0.5241790192531193 1.0 0.798098519476735 233 Q03164,O95302,Q13432,Q86X55,Q96KQ7,Q15047,Q9NYU2,Q9UKN8,Q13418,Q9P265,Q6PD62,Q96AY3,Q9H7B4,P31751,P38435,Q96ES7,Q32P28,Q9NWM8,Q8N0U8,P78362,P13674,P51812,P14373,Q86UY6,Q9H9B1,P26885,Q9H2J4,P26572,Q07812,Q96N67,Q9BX68,O95429,Q9UBU8,Q9BXJ9,Q13451,P42345,P46379,Q12824 38 +Positive regulation of nik nf kappab signaling 0.4481090361315762 0.636795151911852 0.5242582844143149 1.0 0.798098519476735 11 P23396,P61586,Q13418 3 +Mitochondrial electron transport nadh to ubiquinone 0.3366022323540432 0.636015509809902 0.5247663130068136 1.0 0.798492399316306 28 O43676,O96000,P03886,O95168 4 +Response to chemokine 0.5238898605086998 0.6342290414209502 0.5259313573154398 1.0 0.799695294318231 4 O94813 1 +Cellular iron ion homeostasis 0.3992455519987962 0.6328898209699129 0.5268055954440394 1.0 0.8008345145739241 14 P09601 1 +Regulation of phospholipid biosynthetic process 0.5217676738656192 0.631725568427288 0.5275662175575528 1.0 0.8009964345034514 6 O75874,Q99653 2 +Macroautophagy 0.2912115095271335 0.6313911493472427 0.5277848016059323 1.0 0.8009964345034514 88 Q9Y3C8,Q9Y5K8,Q8TBX8,P51809,Q9Y371,O95295,Q96KQ7,Q96HY6,Q9Y487,Q99570,Q9BRG1,Q00535,P50851,O14681,O75396,Q9NRR5,P09601,P60520,Q93050,O15269,A6NDU8,Q9Y679,P12235,P42345,P62820,Q9P275 26 +Response to lectin 0.4070710347064498 0.6312883912817917 0.5278519759265257 1.0 0.8009964345034514 2 P07948 1 +Innate immune response activating signal transduction 0.4070710347064498 0.6312883912817917 0.5278519759265257 1.0 0.8009964345034514 2 P07948 1 +Positive regulation of protein localization to membrane 0.3358874156148951 0.6311794383285225 0.5279232046877853 1.0 0.8009964345034514 28 P98194,P31751,Q99653,Q12955,Q13277,P63010,Q86YS7 7 +Regulation of nervous system development 0.2939481013479275 0.6299671543469575 0.528716074246218 1.0 0.801377371416018 55 O15031,P07196,Q96N67,Q9NQC3,Q9UQB8,Q16706,Q13614,O94813,P55209,Q9P265 10 +Centromere complex assembly 0.4978252014187189 0.6290009864944374 0.5293484103774047 1.0 0.801377371416018 8 P49321,P50748,Q6IPU0,Q92674 4 +Regulation of non motile cilium assembly 0.5209968619719085 0.6288453977940929 0.5294502757887278 1.0 0.801377371416018 6 Q15555 1 +Metal ion homeostasis 0.2911294616241194 0.6287090400156284 0.5295395587268192 1.0 0.801377371416018 82 Q96PU5,Q14344,Q9HD20,P98194,Q8NE01,Q9UM00,O43819,Q12955,Q13586,Q07812,Q9HC07,Q9Y487,P09601,Q9UJZ1,P78417,P30519 16 +Protoporphyrinogen ix biosynthetic process 0.4633838783461158 0.6272898939958766 0.5304692267019364 1.0 0.8024051632237555 3 P06132 1 +Regulation of lamellipodium assembly 0.3977637829199988 0.625288499367039 0.5317817267064839 1.0 0.8035251896363218 14 Q16625,P42345,P50570,O94813,Q7L576 5 +Phosphorylation 0.2320638299832769 0.6252603571875467 0.5318001938678305 1.0 0.8035251896363218 275 O15031,Q16625,Q8TBX8,Q8NDZ4,Q9HA64,Q9UHD1,P17858,P85037,P49736,O75376,Q13432,O43823,O00410,A4D1P6,Q96HY6,O14976,Q96M27,Q99570,O94813,P41440,Q9BRG1,Q96KB5,Q02218,Q00535,P05198,Q13418,Q9ULW0,Q9NY27,Q9H7B4,Q9BRR6,P63000,O75414,P31751,P25440,P23396,Q8TF05,Q8WVC6,P78362,P51812,P14373,P50750,P61586,P11802,Q96A49,Q9H2J4,Q05639,P14635,O60566,Q13217,Q96N67,Q07812,Q9NQS7,O14757,O95373,P42771,O95429,P61981,Q8IXB1,P51114,P33121,P42345,Q9HAW4,Q9BZF1,P54652,P49959,P54619,Q13555,O43252,P24941,P24468,Q9Y5P4,Q99653,Q9BUP3 73 +Positive regulation of bmp signaling pathway 0.5197249665478898 0.6241015830257481 0.5325608743654808 1.0 0.8040501911820104 6 Q13418 1 +Cellular response to heat 0.3436123092013592 0.6236481385534425 0.5328586890832465 1.0 0.8043102644362105 24 P42345,Q9UHD1,O15514,Q99615,P09601 5 +Negative regulation of amyloid precursor protein catabolic process 0.4785106010313021 0.6229465291942011 0.5333196603128725 1.0 0.8046549428344433 9 Q9NQC3,Q16799 2 +Positive regulation of protein modification process 0.2664575166347138 0.6229182279509035 0.5333382590188958 1.0 0.8046549428344433 161 Q8NDZ4,Q9UHD1,Q03164,Q13432,O43823,Q96HY6,Q96M27,P41440,Q9ULW0,Q00535,Q13418,Q9P265,Q6PD62,Q9H7B4,P63000,P31751,P23396,P38398,Q92797,P50750,P61586,Q96A49,Q05086,P14635,Q96N67,Q9NQS7,Q16763,O95429,P51114,P42345,Q9NVI1,P33121,Q9HAW4,Q9BZF1,P54652,P49959,P54619,Q99653,Q12824 39 +Regulation of metal ion transport 0.2929515444723303 0.6204173317930324 0.5349830646239122 1.0 0.8060456690511977 52 Q96PU5,P50570,Q9UHD1,P28161,P54652,Q12955,Q13586,Q07812,O43865,Q13555,P14373,Q99653,P61586,P78417 14 +Mitochondrial dna replication 0.5073612944304007 0.6187148970396227 0.5361041944186888 1.0 0.8063077680196095 7 Q9BQP7,Q96RR1 2 +Response to oxidative stress 0.2883045508656364 0.6179118362616701 0.5366334562797079 1.0 0.8065870297812785 95 Q99720,Q9BXW9,Q15392,P28074,O75874,P00374,P18887,O95168,Q7Z2K6,Q8TED1,P10620,Q8N0U8,Q15165,Q14145,O95831,P09601,Q05086,P30519 18 +Positive regulation of smad protein signal transduction 0.4038274408044072 0.6161865188857618 0.5377714248834802 1.0 0.8077288974920456 2 Q8N1F7 1 +Regulation of calcium ion transport 0.3308240469590154 0.6156419280764138 0.5381308724007827 1.0 0.8080195932577251 29 P54652,Q13586,Q07812,Q13555,P14373,P61586,P78417 7 +Artery development 0.506395795443583 0.6150110104079121 0.5385474491353912 1.0 0.8080195932577251 7 Q68CP9,Q96AY3 2 +Calcium ion import into sarcoplasmic reticulum 0.4035030814142029 0.6146822868585111 0.5387645598797541 1.0 0.8080195932577251 2 O75844 1 +Negative regulation of mrna metabolic process 0.3028932950643487 0.6136781175752425 0.5394280512555651 1.0 0.808132856955835 46 Q6PD62,P67809,Q92804,Q99729,P98175,Q14011,Q16629,P16989,P35637,P50750,P38159 11 +Regulation of muscle cell differentiation 0.3761719241048404 0.6130109250798644 0.5398691159164015 1.0 0.8086045257330999 16 Q13547,Q9BYT8,P42345,P50750 4 +Response to oxygen levels 0.2906265735048068 0.6108008288968867 0.5413314446019606 1.0 0.8100371955431347 60 Q6P6C2,P55786,Q9Y487,P00846,P09601,O95831,P30519 7 +Auditory receptor cell morphogenesis 0.4590684024822794 0.6096106220575527 0.5421197735757564 1.0 0.8108380269732186 3 O95487 1 +Regulation of wound healing spreading of epidermal cells 0.5162048499216644 0.6060868196229212 0.5444571028251075 1.0 0.8133843751626956 4 P42345 1 +Wound healing spreading of epidermal cells 0.5162048499216644 0.6060868196229212 0.5444571028251075 1.0 0.8133843751626956 4 P42345 1 +Positive regulation of small gtpase mediated signal transduction 0.5147984388691726 0.6058312830408291 0.5446267941477683 1.0 0.8134481798346009 6 Q15555 1 +Zymogen activation 0.4557996046360576 0.6040175110547992 0.5458320000726689 1.0 0.8140347167244399 10 Q15392 1 +Arp2 3 complex mediated actin nucleation 0.4407223066623685 0.6035410711306214 0.5461488016259741 1.0 0.8140347167244399 11 Q13576,Q7L576,P14373,O15145 4 +Actin nucleation 0.4407223066623685 0.6035410711306214 0.5461488016259741 1.0 0.8140347167244399 11 Q13576,Q7L576,P14373,O15145 4 +Fibroblast proliferation 0.384170343850357 0.6034493628339889 0.5462097921348372 1.0 0.8140347167244399 15 P14635,P11802,Q71SY5 3 +Histone h3 k9 methylation 0.4404728106844168 0.6024279642336967 0.5468893002983561 1.0 0.8143591022108947 11 Q96KQ7,Q15047,Q12824 3 +Regulation of protein localization to cell surface 0.4399736082448979 0.6002028504146564 0.5483710542299736 1.0 0.815207863537741 11 Q15907,Q96PU5,Q13277,Q92538 4 +Regulation of glycolytic process 0.4548630316523355 0.5999955034195026 0.5485092322466909 1.0 0.815207863537741 10 Q13131,O75376,O15294,P54619 4 +Cerebral cortex development 0.3354276351142145 0.5962680084578806 0.5509961992393784 1.0 0.8178703760203 26 P07196,Q8WXH0,Q9NQC3,O94813,P61586,O94901 6 +Protein methylation 0.287957450867583 0.5961401336037163 0.551081615038369 1.0 0.8178703760203 63 Q03164,Q9H7B4,Q15047,Q12824 4 +Transcytosis 0.4895077988197637 0.5960191820512766 0.5511624123133991 1.0 0.8178703760203 8 O60763,Q96QK1,Q13492,P20339,Q15907 5 +Muscle organ development 0.3154140794108846 0.5948596685005281 0.5519372785371628 1.0 0.8184514366456169 36 P46939,P51114,P85037,Q15648,P16989,Q9Y5Q8,P61586,P24468,P41440,Q9NQ29,Q9BYT8,Q00535 12 +Pyrimidine ribonucleoside triphosphate metabolic process 0.5008121552014175 0.5937294204735806 0.5526931021182664 1.0 0.8190034726277156 7 O75414 1 +Anoikis 0.5118966391311087 0.5923825097063621 0.5535944757327611 1.0 0.8197702754378334 5 Q07820,P42345 2 +Intraciliary transport 0.5116422395539849 0.5914574513824608 0.5542139559585315 1.0 0.819929469254123 5 A0AVF1 1 +Neurotransmitter receptor transport to plasma membrane 0.5114153581335994 0.5887477054833801 0.55603053082721 1.0 0.8217595893252235 4 Q13277 1 +Protein localization to postsynapse 0.5114153581335994 0.5887477054833801 0.55603053082721 1.0 0.8217595893252235 4 Q13277 1 +Antigen processing and presentation of exogenous antigen 0.4876307273082256 0.5886555147813973 0.5560923852208624 1.0 0.8217595893252235 8 P50570,Q03518 2 +Trna methylation 0.4521216253331784 0.5882741454793957 0.5563482966532793 1.0 0.8219481522972573 10 O75648,Q9NNW5,Q7Z2T5 3 +Antigen processing and presentation of peptide antigen 0.422009536259742 0.5880179262808096 0.5565202604702775 1.0 0.8219486606082158 12 Q03519,Q9NZ08,P50570,Q03518 4 +Sprouting angiogenesis 0.4218357259684758 0.5872181064857431 0.5570572333604811 1.0 0.8219486606082158 12 P09601,P61586,O94813 3 +Protein hexamerization 0.5096778660629069 0.5870234290424146 0.5571879716193442 1.0 0.8219486606082158 6 Q96RR1 1 +Regulation of lamellipodium organization 0.3713161679936355 0.5868629889431295 0.5572957285599724 1.0 0.8219486606082158 16 Q16625,P42345,P50570,O94813,Q7L576 5 +Estrogen metabolic process 0.4985781426437157 0.5852827343363082 0.5583576222954774 1.0 0.8221984656968924 7 Q53GQ0 1 +Positive regulation of i kappab kinase nf kappab signaling 0.3220553018830226 0.5848356303537736 0.5586582440091454 1.0 0.8221984656968924 32 P98194,Q9Y3E0,P14373,P09601,P61586,O43657 6 +Regulation of granulocyte chemotaxis 0.4865072571026089 0.5842627467574966 0.5590435517375778 1.0 0.8221984656968924 8 O94813,P63000,Q00013 3 +Xenobiotic catabolic process 0.5088511579475881 0.5840049269761197 0.5592169972143166 1.0 0.8221984656968924 6 P78417,P33121 2 +Lysine metabolic process 0.5100962754430645 0.5840004345977323 0.5592200196449433 1.0 0.8221984656968924 4 Q9BQT8 1 +Post translational protein modification 0.4357771502635632 0.5816072544301912 0.5608312553844881 1.0 0.8240103261451905 11 O60725,Q32P28 2 +Regulation of mitotic cell cycle spindle assembly checkpoint 0.5093435194627108 0.5812968861786962 0.5610403788643397 1.0 0.824128563862637 4 P14635,Q9Y6G9 2 +Regulation of endocytosis 0.309187862078761 0.5806694110310717 0.5614632815063607 1.0 0.8243673193954897 39 Q96PU5,P41440,Q13432 3 +Negative regulation of phagocytosis 0.4973039379552016 0.5804829575111407 0.5615889762475674 1.0 0.8243673193954897 7 Q08722,P41240 2 +Endoplasmic reticulum organization 0.298549252281354 0.5780053904804038 0.5632604799025185 1.0 0.8262529503676513 46 Q9P0I2,Q9NPA0,P61619,Q5JRA6,Q9C0E8,Q9NQC3,O14976,Q9Y5P4,P46379,Q9NP72,Q9BRK0 11 +Substrate dependent cell migration 0.5068409889403186 0.5766867193770507 0.5641511054997876 1.0 0.8268021006249461 6 Q9Y5K6,O94813 2 +Positive regulation of phospholipid metabolic process 0.5072929608899097 0.5757150785131323 0.564807781756919 1.0 0.8275532398276148 5 Q99653,Q9UJZ1 2 +Positive regulation of epithelial cell proliferation 0.3591064938729714 0.5753550733839485 0.5650511818616901 1.0 0.8275532398276148 17 Q9H2J4,P09601 2 +Regulation of dna templated transcription elongation 0.3274239943679716 0.5749504790609861 0.5653247889733155 1.0 0.8275873973481072 28 Q86V81,P50750 2 +Negative regulation of binding 0.316966513798507 0.5747571146016159 0.5654555742672622 1.0 0.8275873973481072 34 O75381,P09601,P35269,Q07812,Q9HCM4,O95816 6 +Pigment granule localization 0.5067143695578797 0.5736313556727327 0.5662172887514272 1.0 0.8281251031373612 5 P62820,Q9H267,Q15907 3 +Neuron projection regeneration 0.505811222784794 0.5729496355427559 0.5666787955776407 1.0 0.8284211934992287 6 P07196 1 +Embryo development ending in birth or egg hatching 0.2604377141931068 0.5725590969988861 0.5669432612684093 1.0 0.8284211934992287 131 O15031,Q9H0G5,O43772,Q15293,Q9NR56,Q96MU7,Q6PD62,Q96AY3,Q14344,P62993,P31350,P25440,P38398,Q9BZK7,Q15648,P16989,Q6W2J9,Q6DKJ4,Q9HCK8,Q13895,Q9HCM4,P26572,P67809,P55199,P14635,Q9NQC3,Q9NVR5,Q9BRT9,Q14145,Q4VCS5,O14757,Q08J23,Q9NPQ8,O43819,Q16706,P24468,Q9Y5P4,P49321,O60313,P43246,Q12824 41 +Positive regulation of type i interferon production 0.3584651622551826 0.5718350048698391 0.5674337599222155 1.0 0.8284211934992287 17 Q9NUD5,P41440 2 +Regulation of dna directed dna polymerase activity 0.4949635246877296 0.571701441700122 0.5675242575595534 1.0 0.8284211934992287 7 Q9BRX5,Q9BRT9 2 +Regulation of dephosphorylation 0.335353602105963 0.5716138475703292 0.5675836119681728 1.0 0.8284211934992287 24 O95429,P78318,P42345,Q9UHD1,Q13614,Q99653 6 +Protein k11 linked ubiquitination 0.4657461991145019 0.5706441076488464 0.5682409131805732 1.0 0.8288673850598905 9 Q9H1A4,Q9UJX4,Q9UJX3,Q16763 4 +Vesicle cytoskeletal trafficking 0.3777801600264771 0.5704046855066941 0.5684032523656133 1.0 0.8288673850598905 15 O94832,O95295,P62820,Q9Y2T2,Q9UM54,P43034 6 +Embryonic neurocranium morphogenesis 0.4484101232965636 0.5666253903131578 0.5709687208474166 1.0 0.8305235299156564 3 Q93074,Q6UB35 2 +B cell mediated immunity 0.3673417556149443 0.5657581470972022 0.571558201282208 1.0 0.8310035945106274 16 Q9UQ84 1 +Meiotic chromosome segregation 0.3413869261707442 0.565073466486648 0.5720237950841487 1.0 0.8312410347642024 22 Q9BXW9,O60566,Q96KQ7,P46379,O94901 5 +Pyrimidine containing compound biosynthetic process 0.4166729951176088 0.5636335564197731 0.5730035447368438 1.0 0.8312410347642024 12 P17812,O75414 2 +Kinetochore organization 0.5032182296581105 0.5635757481724032 0.5730428954854418 1.0 0.8312410347642024 6 Q9NTJ3,P50748 2 +Carbohydrate metabolic process 0.2594078952592572 0.5634857976445978 0.5731041284088627 1.0 0.8312410347642024 130 P11310,P85037,O75376,Q10713,Q13614,Q9NR45,Q02218,Q9BYT8,P30837,Q9BRR6,P48735,P31751,Q92520,P78417,O60476,Q13724,Q13794,O75874,P50416,P34949,Q7LGA3,Q16706 22 +Regulation of protein containing complex assembly 0.2836783389668917 0.563350571514941 0.5731961880861669 1.0 0.8312410347642024 93 O95429,Q16625,Q9UEY8,Q71SY5,Q9Y371,Q9UQB8,P35611,Q969V3,Q96F07,O94813,P61586 11 +Response to steroid hormone 0.2816363592339571 0.5632294844216258 0.5732786280968227 1.0 0.8312410347642024 68 Q9H7B4,Q9NUQ7,P07196,O75874,O75376,Q86X55,Q96HY6,O94813,O95831,P61586,Q05086 11 +Negative regulation of protein binding 0.3375930646978939 0.5627098035390922 0.5736325074926754 1.0 0.8314060849154696 23 O75381,P35269,Q07812,Q9HCM4,O95816 5 +Cell morphogenesis involved in differentiation 0.2768917241975477 0.5624434676804498 0.5738139103970943 1.0 0.8314060849154696 107 O15031,Q96PU5,Q9P265,Q9Y4F1,P07196,Q12955,Q96N67,Q9UQB8,O94813,P41440,P61586,Q05086,Q13418 13 +Regulation of mast cell activation 0.5039417316636469 0.5620173829864896 0.5741041756747007 1.0 0.8314060849154696 4 P09601 1 +Response to hormone 0.261418611750179 0.5619190544547404 0.5741711707252635 1.0 0.8314060849154696 164 Q15392,Q86X55,O43823,Q9BSK2,Q9UQB8,Q96HY6,Q6IQ22,O94813,Q8IZL8,Q86YS7,P42785,Q9H7B4,P43490,P08574,P09601,P61586,P11802,Q05086,O95831,P33121,P07196,O75874 22 +Regulation of smoothened signaling pathway 0.4454215078625673 0.5599602271603189 0.5755065667191155 1.0 0.832586961698883 10 Q96J42 1 +Vesicle mediated transport to the plasma membrane 0.2977490458492797 0.5570433620590794 0.5774978030551932 1.0 0.8341490251119656 45 Q4J6C6,Q567U6,Q8IYI6,O43752,Q9UBQ0,P50570,Q12955,Q9BZG1,P36405,Q15907,P98194,P61026,Q13277,Q96KP1,O00471,P41240,Q8N2H4,Q9NV70,Q96QK1 19 +Renal system process 0.4621867385613898 0.5563378575542416 0.5779799117382265 1.0 0.8344690814953976 9 Q9NQH7 1 +Cell projection organization 0.2511352922354176 0.5559845090649573 0.5782214446645229 1.0 0.8346296923210756 222 O15031,Q9Y5K8,Q16625,Q15555,Q86X55,Q9UQB8,Q13614,O94813,O14976,P41440,Q96J42,Q92538,Q13418,Q13641,Q9P265,Q14141,P50570,Q9UBB6,P00374,Q12955,Q32P28,Q9BZG1,Q9Y2J2,P61586,Q05086,Q9Y4F1,Q8WXH0,Q13277,Q96N67,Q9NQC3,Q9NVR5,O00471,Q96F07,A6NIH7,Q9Y5K6,Q96PU5,O95429,P51114,P42345,P07196,O43815,P62820,Q13555,Q9BUP0 44 +Regulation of regulated secretory pathway 0.3553658312525817 0.5549347309465616 0.5789393049961169 1.0 0.83538293477801 17 O00186,Q4J6C6,P51809,P07948,O95295,P35080,P09601,P20339,Q00535 9 +Trna transcription 0.5007885024654906 0.5548400145158647 0.5790040946634973 1.0 0.83538293477801 6 Q9Y5Q8 1 +Spinal cord development 0.4292879706535552 0.5532526584959527 0.5800904133786449 1.0 0.836591318988125 11 Q9UKA9,O96019,P07196,O75312,Q14203,Q6Y7W6,P25325,Q93074 8 +Response to vitamin d 0.5003405312447273 0.5532345436099939 0.5801028159452468 1.0 0.836591318988125 6 O15164,Q15648,Q8TB36 3 +Activation of protein kinase b activity 0.4446446832942042 0.5516855621163029 0.5811638035075988 1.0 0.8377442226079382 3 P42345 1 +Mesonephros development 0.4998093882629524 0.5513330920503071 0.5814053575133302 1.0 0.83790387406758 6 Q13418,O94813 2 +Snrna processing 0.3645427518404603 0.5510632783812486 0.5815902973438445 1.0 0.837981881418054 16 Q96SY0,Q13868,Q96B26,Q9NQT5 4 +Regulation of perk mediated unfolded protein response 0.3892312682452117 0.5496483973579095 0.5825605568221823 1.0 0.8385356131921934 2 P18031 1 +Erad pathway 0.3048811325144436 0.5486983079914267 0.5832125075482764 1.0 0.8388309583346722 39 Q92575,Q9UBV2,Q9NYU2,P46379,Q9Y679 5 +Regulation of protein k63 linked ubiquitination 0.4991926072880015 0.546775765784089 0.5845327943477441 1.0 0.8403314812817883 5 O00571,O95071 2 +Meiotic cell cycle process 0.3107478775594262 0.5455142526375197 0.585399880729442 1.0 0.841200456696457 35 Q9BXW9,P54652,O60566,Q96KQ7,Q9NQS7,Q96B01,P46379,P49959,Q08J23,O94901,Q15021 11 +Regulation of cell shape 0.3228327119269418 0.5452957801717846 0.585550105902416 1.0 0.8412276246716476 28 O15031,Q9UQB8,Q9Y2J2,P61586 4 +Renal water homeostasis 0.4426256547320822 0.5437307611769692 0.5866267610888669 1.0 0.8418304282113085 3 P17252 1 +Negative regulation of phosphoprotein phosphatase activity 0.3869607525137846 0.5395239264345454 0.5895253920952472 1.0 0.844854510461332 2 P04899 1 +Sno s rna processing 0.4570877848288742 0.5360708422781209 0.5919095907426855 1.0 0.8470454859948602 9 Q9NQT5 1 +Negative regulation of mapk cascade 0.3185878083261486 0.5347225579493006 0.5928417204498051 1.0 0.8475215490295585 29 P78318,P57105,Q99956,O75376,P18031,P07948,Q96S59,P41240,Q96J02,Q8NC56,Q96P70,Q96KB5,P31689,P43034 14 +Regulation of chromatin assembly or disassembly 0.379504723186716 0.534226928867398 0.5931845402148084 1.0 0.8476333180049214 14 Q15047 1 +Regulation of chromatin assembly 0.379504723186716 0.534226928867398 0.5931845402148084 1.0 0.8476333180049214 14 Q15047 1 +Negative regulation of immune effector process 0.4727674299327365 0.5314695788424261 0.5950934167591353 1.0 0.8498067428873916 8 P09601,P04439,Q96FV9,Q08722 4 +Activated t cell proliferation 0.4947412616970453 0.5310942240385665 0.5953534865798114 1.0 0.8498067428873916 5 P23396 1 +Neuron development 0.259115527491168 0.5305036164320739 0.5957628022788328 1.0 0.84980955264315 163 O15031,Q15555,Q86X55,Q9UQB8,Q13614,O94813,P41440,Q02218,Q9P265,Q9UBB6,P00374,Q12955,Q32P28,Q9Y2J2,P61586,Q05086,Q9Y4F1,Q96N67,Q96F07,Q96PU5,P07196 21 +Vitamin d receptor signaling pathway 0.4392433807043421 0.5304950158296227 0.5957687638027453 1.0 0.84980955264315 3 Q15648 1 +Regulation of vitamin d receptor signaling pathway 0.4392433807043421 0.5304950158296227 0.5957687638027453 1.0 0.84980955264315 3 Q15648 1 +Organophosphate ester transport 0.3166066703600082 0.5292571536794437 0.5966270738263344 1.0 0.8507403300165112 30 Q86VD7,Q8TB61,Q9BZF1,O43808,Q9BSK2,Q8TDW0,O00400,Q08722,P12235,P41440,Q9Y5P4 11 +Sulfate transport 0.438351719662558 0.5270248882514739 0.5981763053013816 1.0 0.8521052727953413 3 Q9UBX3,Q02978 2 +Intermediate filament bundle assembly 0.4378405377563082 0.5250391569138249 0.5995559706413349 1.0 0.8522512637060415 3 P07196 1 +Embryo development 0.2520913176447732 0.5248548751920588 0.5996840806893584 1.0 0.8522512637060415 190 O15031,O43772,Q03164,Q15293,Q9NR56,Q13547,Q8IZL8,Q6PD62,Q96AY3,Q14344,Q9H6E4,Q9BZK7,P16989,Q9HCM4,Q9H9B1,Q68CP9,P26572,P14635,Q9NQC3,Q9NVR5,Q9BRT9,Q14145,Q4VCS5,Q9C0E8,O43819,Q16706,Q9Y5P4,P46379,O60313,Q12824 30 +Mitotic g2 m transition checkpoint 0.3687431322065291 0.5248316938927583 0.5997001968784379 1.0 0.8522512637060415 15 Q9HAW4,Q6NUQ1,P38398,Q9Y619,P49959,O14757 6 +Protein kinase b signaling 0.3345236868382053 0.524672720774346 0.5998107240434964 1.0 0.8522512637060415 22 Q13641,O95429,P42345,Q9NQC3,Q13418 5 +Positive regulation of glucose metabolic process 0.49280731891257 0.5243321537653305 0.6000475366509819 1.0 0.8522512637060415 5 Q13794 1 +Positive regulation of cellular carbohydrate metabolic process 0.49280731891257 0.5243321537653305 0.6000475366509819 1.0 0.8522512637060415 5 Q13794 1 +Schwann cell development 0.4924344435251788 0.5230320052811649 0.6009519811043686 1.0 0.8522512637060415 5 P31751,Q13418 2 +Cytokinesis 0.2817929360074179 0.5228161811058684 0.6011021781268244 1.0 0.8522512637060415 55 Q13432,O75935,Q9Y371 3 +Regulation of protein monoubiquitination 0.3830684398313324 0.5223205096802581 0.601447191459235 1.0 0.8522512637060415 2 O75340 1 +Positive regulation of protein monoubiquitination 0.3830684398313324 0.5223205096802581 0.601447191459235 1.0 0.8522512637060415 2 O75340 1 +Neuron differentiation 0.2519725577497273 0.5222433187413557 0.6015009284457653 1.0 0.8522512637060415 194 O15031,Q8WUJ1,Q15555,Q86X55,Q9UQB8,Q96KQ7,Q13547,Q13614,O94813,P41440,Q02218,Q9P265,Q9UBB6,P00374,Q12955,Q32P28,Q9Y2J2,P61586,Q05086,Q9Y4F1,Q96N67,Q9NQC3,Q96F07,Q96PU5,P07196,Q13555 26 +Carbohydrate derivative transport 0.3340408643029035 0.5218750980966048 0.6017572975120158 1.0 0.8522512637060415 22 Q86VD7,O43808,Q96AA3,Q8TDW0,O00400,Q08722,P41440 7 +Response to axon injury 0.421805185247986 0.5211993218950862 0.6022279264947583 1.0 0.8525684192542369 11 P00374,Q96G23,P07196,Q07812,Q99707,P46060 6 +Regulation of immune response 0.2764815111867926 0.5209337915121878 0.6024128944763498 1.0 0.8526418475509273 101 Q9NUQ9,P51809,Q14166,P41440,O43657,Q96RT1,P23396,Q9NUD5,Q9NPR9,P51812,P14373,Q08722,P09601,Q9NZ08,Q9NQT5,Q07812,Q96J02,Q9NQC3,Q9UJZ1,P28070,P46379,O96028 22 +Double strand break repair 0.2800655754317203 0.5187927547702665 0.6039052709037662 1.0 0.8539993742625885 88 P49736,P25205,P46063,Q96B01,Q9NY27,Q9BXW9,O95071,Q9UNS1,P18887,Q9Y2K7,Q9NRR5,Q68CP9,Q9BRT9,O14757,Q9UBU8,Q96T76,P35637,Q96FF9,O96028,P49959,Q96SB8 21 +Aorta development 0.4909130246528571 0.5177393458096955 0.604640142347509 1.0 0.8548498679934103 5 Q96AY3 1 +Regulation of cellular response to osmotic stress 0.4901893135289863 0.5152286810083758 0.6063932292282344 1.0 0.8562576144182289 5 P16989 1 +Inositol lipid mediated signaling 0.4055602887396007 0.5140702850038541 0.6072028517637886 1.0 0.8567712485459977 12 Q8NDZ4,Q05086 2 +Adaptive immune response 0.3000444886012668 0.5137021964965603 0.6074602160473899 1.0 0.8569456384055448 39 Q9UQ84,Q9NQT5,P14373 3 +Divalent inorganic cation homeostasis 0.2805523388694698 0.5128664861240064 0.6080447181201696 1.0 0.8573925741311481 56 Q14344,Q9HD20,P98194,Q9UM00,Q12955,Q13586,Q07812,Q9HC07,Q9UJZ1,P78417,Q8NE01 11 +Response to heat 0.3112754572315557 0.5124064160297511 0.6083666015407356 1.0 0.857497903886496 32 P42345,Q9UHD1,P07948,P54652,O60884,Q9H078,O15514,Q99615,P17252,P09601,Q14232,P31689,P05198 13 +Negative regulation of amyloid beta clearance 0.3807979240998987 0.5123770741461158 0.6083871328698289 1.0 0.857497903886496 2 Q16850 1 +Regulation of leukocyte migration 0.3254186975115401 0.5113299895541864 0.6091200089262792 1.0 0.8583420099387912 24 P09601,P61586,Q08722,O94813 4 +Toll like receptor signaling pathway 0.3897039103437014 0.5098672282513003 0.6101444826746703 1.0 0.8591940731509237 13 Q9NPR9,P41440,Q9NQC3 3 +Regulation of ras protein signal transduction 0.3234948157903142 0.5098007791107413 0.610191039803849 1.0 0.8591940731509237 25 Q15555,P41440 2 +Regulation of cysteine type endopeptidase activity 0.2853520703340837 0.5091732315263491 0.6106308044245154 1.0 0.8591940731509237 49 O95831,Q96K76,Q15392,Q96F07 4 +Negative regulation of peptidyl tyrosine phosphorylation 0.4777965617257447 0.5087449233618275 0.6109310293416388 1.0 0.8591940731509237 7 P30153,Q9BRG1,Q9UNH7,Q99816 4 +Regulation of hematopoietic stem cell differentiation 0.4884039199708607 0.5078258153916999 0.6115755038151118 1.0 0.8597218954223407 4 P19525,Q96J02 2 +Cell growth 0.2777873406998836 0.507296527532492 0.6119467746867557 1.0 0.8597939771980199 94 Q96PU5,O75414,Q96J02,Q9BSK2,Q13868,Q9Y2J2,O14681,Q96F07,O94813,P61586,Q9HBM6,Q96K76,Q9P0J0,Q5BJF2,Q9P265 15 +Sulfur compound transport 0.4038812407545279 0.5067333988514703 0.6123418927901736 1.0 0.8598558012305682 12 Q8TDW0,Q70HW3,P10620,O00400 4 +Negative regulation of stress activated protein kinase signaling cascade 0.4317692018198829 0.503849480617721 0.6143671537009716 1.0 0.8615665469808284 10 P78318,O75376,Q96J02,Q96KB5,P31689 5 +Retina development in camera type eye 0.3643667945160053 0.5032884463949423 0.6147614882640688 1.0 0.861742252476942 15 Q15555,Q15648,Q07812,P20020,Q16706 5 +Mitochondrial proton transporting atp synthase complex assembly 0.4870175964129784 0.5030877963201112 0.6149025463796949 1.0 0.8617514137187323 4 Q15070 1 +Response to ethanol 0.3397815120325045 0.502608125401974 0.6152398153980281 1.0 0.8620354893787768 19 P50416,P61586,Q9BRK5 3 +Amino acid transmembrane transport 0.3641295886018384 0.502131071510004 0.6155753249742417 1.0 0.8622217012971573 15 P30825,Q96NB2,O60831,Q8TDW0,Q15758 5 +Phospholipid biosynthetic process 0.2790901889255746 0.5014937194650918 0.6160236968456672 1.0 0.8625678255723156 57 Q96BW9,Q8TBX8,Q9UHD1,Q9NPH0,Q8WWI5,Q10713,O60762,Q13614,Q99570,P48651,Q9HCL2,O15269,Q9UG56,P42356,O15228,O75874,P14324,Q9BVG9,Q99653,Q7L5N7 20 +Visual behavior 0.486294778081499 0.5006240472819472 0.6166357352061698 1.0 0.8629071954522911 4 Q00535 1 +Protein monoubiquitination 0.3332020091687042 0.5001337298305557 0.6169809173273084 1.0 0.8629650123141348 21 Q13616,Q96T88,Q9C0C9 3 +Actin filament bundle organization 0.2996283565150688 0.4992144865557057 0.6176282901218602 1.0 0.863493414779711 37 O95429,Q9Y613,P29966,Q9UQB8,P35611,Q08722,P61586 7 +Proteolysis 0.2344774751554691 0.4966823317664816 0.6194130837123129 1.0 0.8647606400565526 359 Q15392,Q96T88,Q9H7D7,Q8IYS1,Q9NP73,Q96HY6,Q13547,Q10713,P52888,Q969V3,Q9NYU2,Q9C0C9,Q9UL46,A4D1P6,Q9BRG1,P42785,Q9BYT8,Q9BT78,Q8WU17,P67812,P78318,Q9UJX3,Q9H1A4,P23396,Q9BZK7,Q96ES7,Q9UHG3,Q9UBV2,P51812,Q99436,P49721,Q9NRR5,Q7Z2K6,Q96K76,P61586,Q9Y385,Q05086,Q16740,Q9H2J4,Q9Y5A7,Q92575,Q96DX4,Q9NZ08,P28074,Q9NUQ7,P55786,Q92688,Q13217,Q07812,Q96J02,Q9H8M7,Q96F07,Q14145,O95831,Q9NQH7,Q9Y679,Q16763,Q5T4S7,Q9UJZ1,Q9Y5K6,Q96PU5,Q8IXB1,Q13794,Q13616,O43791,P20618,Q9H4L4,P61009,O95816,O43847,Q9P275,P28070,P46379,Q9HB40,Q9P0J0 75 +Pyrimidine nucleobase biosynthetic process 0.4839268705732724 0.4955775027383002 0.6201925286421721 1.0 0.8647606400565526 6 P17812,P42345 2 +Vesicle mediated transport 0.2275682902024663 0.4954399588027971 0.6202895942959505 1.0 0.8647606400565526 324 Q7Z3U7,Q13432,Q5BJH7,A4D1P6,Q99570,Q8NC96,P41440,Q9BRG1,Q92538,Q8WU17,P50570,O14653,Q9UHQ4,P14373,P09601,P60520,Q05086,Q15907,O43760,Q13492,O43731,Q96PU5,Q8N2H4,Q9UP83,O95249,Q96CW1,Q8WTV0,Q9BRK5,Q567U6,P57105,P49257,O60749,Q9NRW7,O95295,O43752,O95070,Q13614,Q9UBQ0,Q9Y3B3,Q7L576,Q00535,P63000,Q96RL7,Q12955,Q5KU26,Q9BXF3,Q9H267,Q08722,O00161,Q9Y282,Q14746,P40616,P24390,P83436,Q9Y3E0,P51809,Q6NUQ1,Q6IQ22,Q9C0C9,Q86YS7,O75396,Q9Y5K6,P54652,Q96D71,Q5JRA6,O14976,O15126,P31751,O95782,Q9BZG1,Q12907,O94832,P98194,Q13277,O00471,Q96PC5,Q6WKZ4,P20645,Q9HAS0,P62820,P63010,O94979 82 +Citrulline metabolic process 0.4292667099286273 0.4921438867819377 0.622617629231299 1.0 0.8666859045753372 3 P27708,P23634 2 +Citrulline biosynthetic process 0.4292667099286273 0.4921438867819377 0.622617629231299 1.0 0.8666859045753372 3 P27708,P23634 2 +Carbohydrate biosynthetic process 0.2947742860973459 0.4911821783644705 0.6232976026135872 1.0 0.8668789497053061 41 P11310,P31751,Q92520,Q7LGA3,Q9NR45,Q9BYT8 6 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.369935753102163 0.488660449152401 0.6250821090318537 1.0 0.8678470788698863 14 Q92688,O95831,Q13794 3 +Cellular response to peptide hormone stimulus 0.2776446079181502 0.4881922949308654 0.625413641668028 1.0 0.8678470788698863 55 Q8TBX8,Q9HCD5,Q9BSK2,Q13131,Q9UQB8,Q6IQ22,O60343,Q86YS7,Q7L576,P62993,P31751,P20020,P43490,Q96A49,P11802,O14654,O60763,O43865,P41240,P61981,Q9BZF1 21 +Lamellipodium assembly 0.3427142737828101 0.4879864756812035 0.6255594206097901 1.0 0.8678470788698863 17 Q16625,P42345,P50570,O94813,Q7L576 5 +Ether biosynthetic process 0.471899566233796 0.4877550661497106 0.6257233422820494 1.0 0.8678470788698863 7 O15228 1 +Forebrain development 0.2770479535181408 0.4834256972081494 0.6287935058251739 1.0 0.8698015975633911 54 P07196,P18887,Q8WXH0,Q07812,Q96N67,Q9NQC3,Q13547,O94813,Q02218,P61586,O94901 11 +Negative regulation of nuclear division 0.3417162829208461 0.4828540980699373 0.6291993358829031 1.0 0.8699948119014623 17 O75414,P14635,Q9Y6G9,O60566,O43684,O43264,P50748,Q5JVF3,Q96DY7,O14757 10 +Chemokine c c motif ligand 5 production 0.4263465282284274 0.481123446016877 0.6304287653453984 1.0 0.870747449504662 3 O00571,P78540 2 +Positive regulation of endoplasmic reticulum unfolded protein response 0.4802471520041907 0.4801921278379954 0.6310907839404429 1.0 0.8710983757643779 4 Q07812 1 +Positive regulation of ire1 mediated unfolded protein response 0.4802471520041907 0.4801921278379954 0.6310907839404429 1.0 0.8710983757643779 4 Q07812 1 +Regulation of striated muscle cell differentiation 0.4587009265937306 0.4793635648902298 0.6316800089005365 1.0 0.8716146099738312 8 Q13547,Q9BYT8,P42345 3 +Embryonic organ development 0.2891394002671884 0.4792835709875322 0.6317369082279891 1.0 0.8716146099738312 44 Q03164 1 +Atp synthesis coupled electron transport 0.2884454286593017 0.4742298603540398 0.6353360020385297 1.0 0.874508472079678 44 O43676,P13073,P03886,P14635,O95168,O96000,P08574,Q16718 8 +Positive regulation of cell growth 0.3051813014949926 0.4733046195483485 0.6359958668315513 1.0 0.8752286837643217 32 Q96PU5,Q9BSK2,Q13868,Q9HBM6,Q96K76 5 +Positive regulation of nitric oxide synthase activity 0.4239721224027241 0.4722342657981149 0.6367595840729945 1.0 0.8760914724165813 3 P00374 1 +Mitochondrial genome maintenance 0.4404011286977677 0.4717637816574554 0.6370954054330327 1.0 0.8763652925067655 9 Q9BQP7,O60313,Q9BSK2 3 +Protein homooligomerization 0.2939666285001112 0.4711872478115967 0.6375070244079508 1.0 0.8766590719195586 39 Q99720 1 +Long chain fatty acid import across plasma membrane 0.4236628704116056 0.4710813048956261 0.6375826750036253 1.0 0.8766590719195586 3 P33121 1 +Regulation of cytoplasmic translation 0.365761352491374 0.4693026870577466 0.6388532948574084 1.0 0.8778408852116169 14 P42345,P16989 2 +Schwann cell differentiation 0.4761370289084337 0.469064652738727 0.6390234238362245 1.0 0.8778863506529817 6 P31751,Q13418 2 +Ubiquitin dependent erad pathway 0.3011922638996133 0.4684482428225396 0.6394640754280163 1.0 0.8779396737510303 34 Q9UBV2,P46379,Q92575,Q9Y679 4 +Positive regulation of kinase activity 0.2751912242380203 0.468435219026223 0.6394733870937102 1.0 0.8779396737510303 54 Q8NDZ4,P42345,P33121,Q05639,P23396,P14635,Q13432,Q9HAW4,Q9BZF1,Q9NQS7,P54619,Q96M27,Q99570,P49959,Q96A49,Q9ULW0,P61586 17 +Cellular response to insulin stimulus 0.2827548224311688 0.4658455323887686 0.6413260708048569 1.0 0.8799175004446164 47 Q8TBX8,Q9HCD5,Q9BSK2,Q13131,Q9UQB8,Q6IQ22,O60343,Q86YS7,Q7L576,P62993,P31751,P20020,P43490,Q96A49,P11802,O14654,O60763,P61981,Q9BZF1 19 +Regulation of cellular response to heat 0.4755449361496181 0.4654335120891925 0.6416210400739748 1.0 0.8799452756826981 5 P42345,Q9UHD1 2 +Positive regulation of histone modification 0.2920826589703192 0.4647494359910434 0.6421109016035678 1.0 0.8802401959495946 40 Q03164,Q12824,P50750 3 +Connective tissue development 0.323789309910232 0.4639579423248075 0.6426778783717269 1.0 0.8804522003527122 22 Q96HY6,Q9BZK7,P43490,Q9C0E8 4 +Valine metabolic process 0.4750030342815337 0.4636293189670894 0.6429133448742477 1.0 0.8805864629601092 5 P31937,A1L0T0,O15382 3 +Steroid biosynthetic process 0.2822750511921139 0.4622727475979903 0.6438857402635794 1.0 0.8813530025915576 47 Q14739,Q15392,P56937,Q9BZF3,Q9UHQ9,Q53GQ0,O75845 7 +Regulation of receptor internalization 0.4209027507216599 0.4608612285769644 0.6448981698609837 1.0 0.8820539897133342 10 P41440 1 +Positive regulation of cytoplasmic translation 0.4071549895915191 0.4606313037794154 0.645063148725689 1.0 0.8820539897133342 11 O75534,P11940,P67809,P16989 4 +Positive regulation of actin filament depolymerization 0.4208373072442701 0.4605990180477104 0.645086316235868 1.0 0.8820539897133342 3 P60981 1 +Ventricular cardiac muscle cell membrane repolarization 0.3684722672721345 0.4596585933756896 0.6457612947850464 1.0 0.8824118716708633 2 O75844 1 +Ribonucleoprotein complex disassembly 0.4733498926124674 0.4581430723000746 0.6468496558001473 1.0 0.8831455445557851 5 Q07866,Q14562 2 +Postreplication repair 0.4062013633391714 0.4567964292569296 0.6478173725600791 1.0 0.8835108510913093 11 P38398,P56282,P49005 3 +Heart valve development 0.4730842686313636 0.4564274153086233 0.6480826552104375 1.0 0.8835108510913093 4 O94813 1 +Cytoplasmic translational initiation 0.3363292024557276 0.4555523042084057 0.6487119476622945 1.0 0.883860762772399 17 P55010,P42345,O15371 3 +Epiboly 0.4623033547876884 0.4543579896003181 0.6495711842080505 1.0 0.8842229082101087 7 Q92766,P42345,P61586 3 +Morphogenesis of an epithelial sheet 0.4623033547876884 0.4543579896003181 0.6495711842080505 1.0 0.8842229082101087 7 Q92766,P42345,P61586 3 +Lamellipodium organization 0.3188150841992608 0.4536764702182911 0.6500617049181021 1.0 0.8845233408019759 23 Q16625,P42345,P50570,O60749,O94813,Q7L576 6 +Nitrogen compound transport 0.2363733844296062 0.4508114793850284 0.6521254270644237 1.0 0.8866415802080247 560 Q8NFH4,Q9UHD1,O43772,Q7Z3U7,Q13432,Q03519,Q5BJH7,O00410,Q99570,Q8NC96,P41440,Q9BRG1,Q92538,Q6P4A7,Q86V81,P50570,O14653,A0AVF1,P62072,Q32P28,Q9UBV2,Q9UHQ4,Q92945,Q9Y385,P60520,Q15907,Q9BRK0,P67809,P55786,Q16629,P80404,Q8TB36,O60830,Q9Y6M1,O95831,P12235,Q86VD7,Q08J23,A6NIH7,O95373,Q03518,O43731,O95429,Q8N2H4,P61981,Q9UP83,P50416,O95249,Q96CW1,Q9P0J0,Q9Y5M8,Q9NVG8,Q567U6,P61619,P17858,P57105,P52292,P49257,O60749,Q9NRW7,Q9Y371,O43752,O95295,Q8WWI5,O95070,Q07820,Q9UN86,Q15758,Q99595,Q9UBQ0,Q9Y3B3,Q00535,O75381,O43592,Q96RT1,Q96RL7,Q12955,Q8TDW0,Q08722,Q9UI26,Q86U42,Q6P6C2,Q9Y282,Q14746,P40616,P24390,Q9Y679,P83436,O15514,Q9Y3E0,P46379,Q15070,O60725,O75152,Q9HD20,Q96EE3,P51809,Q6NUQ1,O43823,O43808,Q9BSK2,O60831,Q6IQ22,Q86YS7,P30825,O75396,Q96P70,P51991,Q9Y5K6,Q96NB2,P10620,P61009,Q13555,Q9Y5P4,Q99653,O96008,Q5JRA6,Q9Y619,Q10713,Q9NP72,O15126,P31751,O95782,Q969Q5,Q9BZG1,O00400,Q12907,O94832,P98194,Q92688,Q8TB61,Q13277,Q07812,O43865,O00471,Q96PC5,Q6WKZ4,Q8NFH5,Q92973,P20645,P09132,Q9HAS0,P62820,Q9P275,P63010,O94979 146 +Negative regulation of neuron apoptotic process 0.3181390856772819 0.4499419043065917 0.6527523312511425 1.0 0.8868571440073848 23 P09601,P61586,Q07812,P07196 4 +Protein modification by small protein conjugation or removal 0.2462635854564375 0.4477760843676633 0.6543148050086938 1.0 0.8880382713740873 194 Q9Y3C8,Q96T88,Q9UHD1,Q96HY6,Q14527,P52888,Q9C0C9,Q13098,Q9BT78,Q00535,Q6PD62,Q8WU17,O95071,Q9UJX3,Q9H1A4,P23396,P38398,Q96ES7,Q6W2J9,Q9UBV2,Q6DKJ4,Q86UV5,P14373,P50750,Q9Y385,Q15369,Q96K76,Q05086,Q9Y5A7,P45974,Q96DX4,O75155,P55786,O60566,Q6P2C8,Q96J02,Q9H8M7,Q9UJX4,P62841,Q14145,Q16763,Q96PU5,Q9NVI1,Q13616,O43791,Q99653,Q9H4L4,O95816,Q9P275,Q96DY7,Q5T4S7 51 +Positive regulation of protein binding 0.3343546441665297 0.4457202838388485 0.6557993107166231 1.0 0.889111192476336 17 Q9HCM4,P41440,P35611,Q00535 4 +Mitotic dna integrity checkpoint signaling 0.3169590307355194 0.4434569107331183 0.6574352795555869 1.0 0.8899738421704021 23 P61254,Q9BXW9,P78527,Q6NUQ1,Q9HAW4,P38398,Q9Y619,Q13564,P24941,P49959,O14757,P43246 12 +Sno s rna metabolic process 0.4027786085958663 0.4431467886313167 0.6576595643114103 1.0 0.8899738421704021 11 Q9NQT5 1 +Negative regulation of lipoprotein particle clearance 0.4689447707119281 0.4429182396114901 0.6578248739739079 1.0 0.8899738421704021 4 Q92945 1 +Positive regulation of transcription by rna polymerase i 0.37446392291991 0.4424411568586351 0.6581700021745345 1.0 0.8902014533451218 13 Q8IWA0,P17480,Q12824 3 +Positive regulation of embryonic development 0.4678552539680556 0.4415307148243406 0.6588288305503625 1.0 0.8902054903644078 6 Q4VCS5,Q68CQ4 2 +Regulation of rrna processing 0.458426249409615 0.4411452982893265 0.6591078115514184 1.0 0.8902054903644078 7 Q8IWA0 1 +Integrin activation 0.3639312358092772 0.4408076737692609 0.6593522376244789 1.0 0.8903478992880295 2 Q9Y490 1 +Sensory perception of light stimulus 0.3593241527473217 0.4401139460759551 0.6598545816925121 1.0 0.890756769676251 14 Q15555,Q13432,Q9H6K4 3 +Dna replication 0.2594807859689 0.4390314576398651 0.6606387426522604 1.0 0.890756769676251 114 Q96RR1,P49736,Q9Y619,P25205,P46063,Q9BRX5,Q96KQ7,P41440,Q9UBD5,Q9UNS1,Q86V81,P31350,O75717,Q9BTE3,P78362,P50750,Q7Z7L1,P49427,Q96FV9,Q9BQP7,Q9BRT9,Q13416,O14757,Q9UJZ1,P40938,Q9NRG0,P49005,Q9NR33,P24941,P49959,Q96S55,P55209 32 +Regulation of protein binding 0.2848425714763637 0.4387596792595473 0.6608356790733001 1.0 0.890756769676251 43 O75381,P35269,Q92797,O95295,Q07812,Q9HCM4,P35611,Q15691,P41440,O95816,Q00535 11 +Pyrimidine nucleotide metabolic process 0.3504900367842612 0.4374810854561006 0.6617624904053525 1.0 0.890756769676251 15 P17812,O75414 2 +Membrane organization 0.2432822395883152 0.4373246073940497 0.6618759519360706 1.0 0.890756769676251 219 Q15392,P61619,Q5JRA6,P51809,Q13505,Q9Y371,O43752,Q9UQB8,O14976,Q86YS7,P41440,O94901,Q9P0I2,P31751,O14653,Q12955,Q9BUR5,P62072,Q96AA3,Q9BZG1,Q9Y2J2,O75396,P61586,Q9BRK0,P98194,Q13277,O43760,Q9NQC3,Q9H3K2,O15228,Q13794,O95249,Q7L5N7,Q9Y5P4,P46379,Q99653,Q15070,O60313,Q9P0J0,Q9NPA0 40 +Negative regulation of protein tyrosine kinase activity 0.4665422884337209 0.4372300845485412 0.6619444937831562 1.0 0.890756769676251 6 Q9BRG1,Q96FZ7,Q9UNH7,Q99816 4 +Transcription preinitiation complex assembly 0.4012793076645924 0.437225040539737 0.661948151451355 1.0 0.890756769676251 11 P17480,Q12824 2 +Negative regulation of activated t cell proliferation 0.3629581576386638 0.4368105577318331 0.6622487416468057 1.0 0.890756769676251 2 P10644 1 +Macromolecule catabolic process 0.2358238643721212 0.4367236385653883 0.6623117838543771 1.0 0.890756769676251 393 Q9H7D7,A4D1P6,Q99570,Q9BRG1,Q969T7,Q8WU17,Q99575,P62487,Q9BZK7,Q9UBV2,Q92945,Q99436,P49721,Q9Y385,Q96K76,Q16740,P60520,Q05086,Q92575,Q9NQT5,P67809,P28074,Q05639,Q9UG56,Q9UJX4,P98175,O95831,Q08J23,Q96PU5,Q96B26,Q9HCE1,P35637,P24941,P28070,Q9P0J0,Q92804,Q9Y371,Q96HY6,Q13614,O60502,Q9UJX3,Q9H1A4,Q96RL7,P16989,Q6P6C2,Q96DX4,Q9Y679,Q13794,O43791,O15514,O43847,Q9GZR2,P46379,Q9Y4Y9,Q96T88,Q14011,Q6IQ22,Q9NYU2,Q13868,O75396,Q9H2J4,Q9Y5A7,Q96J02,Q14145,Q16763,Q9Y5K6,Q8IXB1,Q13616,P20618,Q5T4S7,Q9BQ61,Q9UL46,Q9UHG3,P62312,Q9NRR5,Q6PGP7,Q99729,Q13217,Q07812,P51114,P42345,O00178,Q9P275,O95816 84 +Regulation of response to cytokine stimulus 0.3299261813616014 0.4359148985258725 0.6628984752224092 1.0 0.8910212794493727 18 Q14166,Q15648,O94813,Q99943,P43034 5 +Cell activation involved in immune response 0.2990256499539392 0.4352943444934568 0.6633487894492289 1.0 0.8912505477070056 32 P09601,Q9UQ84 2 +Response to extracellular stimulus 0.2708285804522518 0.4337142950938464 0.6644959246139264 1.0 0.8923303694307785 83 P11310,P33121,Q13794,P50416,Q9BZK7,Q9Y371,P80303,Q9UMX5,O95831,P09601,O15228 11 +Positive regulation of peptidyl lysine acetylation 0.4299690323614821 0.4332826646658433 0.6648094304282512 1.0 0.8923303694307785 9 P38398,Q12824,Q9P265 3 +Axon extension 0.3180863773683831 0.4330442865423416 0.6649825965741039 1.0 0.8923303694307785 22 P50570,Q9NQC3,O94813,Q7L576,Q00535,Q9P265 6 +Mitochondrial membrane organization 0.2753281269477617 0.4324138853274318 0.6654406280327414 1.0 0.8923303694307785 49 Q13794,Q13505,Q9BUR5,Q07812,P62072,Q9H3K2,Q15070,O60313,Q9P0J0 9 +Endoplasmic reticulum tubular network organization 0.3719338701138007 0.4316490254615363 0.6659965209459264 1.0 0.8923303694307785 13 Q9NQC3,Q9BRK0,Q9C0E8 3 +Rna catabolic process 0.2539535313123542 0.4302353168317246 0.6670244739883335 1.0 0.8923303694307785 119 Q9Y4Y9,Q92804,P60228,Q14011,Q9BQ61,Q7L8L6,Q5JVF3,Q9NP64,Q969T7,P62487,Q99575,O75312,P16989,Q13868,Q92945,P62312,Q53R41,Q6PGP7,Q6P6C2,Q9GZT3,P67809,Q9NQT5,Q99729,Q15024,Q96C86,P98175,Q08J23,P51114,Q96B26,Q9HCE1,O00178,O15514,O95453,P35637 34 +Negative regulation of b cell activation 0.4647619460680675 0.4300823003320157 0.6671357747501614 1.0 0.8923303694307785 5 P07948,Q96FV9,O15347 3 +Regulation of response to interferon gamma 0.4123482574338982 0.4296892295315371 0.6674217191844372 1.0 0.8923303694307785 3 Q15648 1 +Glycerophospholipid biosynthetic process 0.2831567832970329 0.4271841399735492 0.6692452122401533 1.0 0.893535812757487 43 Q96BW9,Q8TBX8,P48651,Q9BVG9,Q9NPH0,Q8WWI5,Q9UG56,Q10713,O60762,Q13614,P42356,Q99570,Q7L5N7,Q9HCL2,O15228 15 +Regulation of synaptic vesicle exocytosis 0.4119247685486511 0.4265758865681375 0.6696882641504749 1.0 0.8937547958641546 10 Q00535,P20339,O95295,P35080 4 +Purine containing compound biosynthetic process 0.2683146222573342 0.4262535055255592 0.6699231331958924 1.0 0.8938820227562772 75 Q9UKU0,Q13126,O75964,O75414,P33121,O43252,P00846,Q53GQ0,P56134,P30520 10 +Positive regulation of mrna splicing via spliceosome 0.3302260428625063 0.4254779140651559 0.6704883185504129 1.0 0.8940514449041166 17 P98179,Q15427 2 +Regulation of transporter activity 0.2878212462502371 0.4249894258477159 0.6708443831427322 1.0 0.8941800079925806 38 Q96PU5,P50570,Q9UHD1,Q03164,P28161,P54652,Q12955,Q13586,O43865,Q99653,P78417 11 +Negative regulation of vasculature development 0.3978278838305578 0.4237288425405454 0.6717635779622877 1.0 0.8950327538324491 11 Q4VCS5,P57105 2 +Regulation of fatty acid transport 0.4626727147665238 0.42337069777267 0.6720248203652461 1.0 0.8950797166316111 5 P33121 1 +Cellular hormone metabolic process 0.3214256131721281 0.4230925986247809 0.6722277022229524 1.0 0.8950926336396243 20 Q53GQ0,Q9HB40 2 +Establishment or maintenance of bipolar cell polarity 0.3698378093872917 0.4227999549959476 0.6724412205036308 1.0 0.8951908683595716 13 Q96RT1,Q13418 2 +Fatty acyl coa biosynthetic process 0.3697883540316429 0.4225921845602146 0.6725928297492099 1.0 0.8952066626581006 13 Q9UKU0,Q53GQ0,P33121 3 +Regulation of production of molecular mediator of immune response 0.3093340411570013 0.4199103978421112 0.6745509115754151 1.0 0.8972535588770991 24 P09601 1 +Positive regulation of cation channel activity 0.451796730937156 0.4189456635745226 0.6752558435949483 1.0 0.8978183756889245 7 Q12955,Q13586,P78417,P28161 4 +Rna phosphodiester bond hydrolysis exonucleolytic 0.3180506932780161 0.4184157086408179 0.6756432033463562 1.0 0.8980321893178451 21 Q13868,Q96B26,Q9NQT5 3 +Attachment of mitotic spindle microtubules to kinetochore 0.4411056015115512 0.4173235524280362 0.6764417634937883 1.0 0.898462769425919 8 Q96DB5 1 +Chromatin organization 0.246196164340332 0.4164889030794936 0.6770522858526848 1.0 0.8989009208647253 178 Q15059,Q8NB78,Q9H7B4,Q96JM7,Q03164,Q86X55,Q9BZK7,Q9NRG0,Q15047,Q14527,Q9Y2K7,P14373,Q9H6W3,P46379,Q6IPU0,Q12824 16 +Histone phosphorylation 0.3086084120866116 0.4159852357048131 0.6774208069894714 1.0 0.8991614424025711 24 O43823,Q9NQS7,P24941,P50750,Q9NY27,O14757,Q00535 7 +Positive regulation of protein acetylation 0.3952819575100195 0.4138972169654885 0.6789493821457089 1.0 0.9005650551575806 11 P38398,Q13131,O00571,Q12824,Q9P265 5 +Smooth muscle cell apoptotic process 0.4497839143500038 0.4123065970230573 0.6801147138932113 1.0 0.901285655192369 7 P42771,Q8NDZ4,P98175 3 +Negative regulation of b cell proliferation 0.4072031148604795 0.4114000083288456 0.6807792478082928 1.0 0.901979702473614 3 Q96IZ0,P07948 2 +Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 0.3220318671080558 0.4104124475372884 0.6815034167466612 1.0 0.902610860904053 19 Q96B26,Q9NQT5 2 +Negative regulation of phosphorus metabolic process 0.2667428110705661 0.4103056613734261 0.6815817396240524 1.0 0.902610860904053 76 P42771,Q16625,Q8TBX8,Q9H7B4,O95429,Q9UHD1,Q8IXB1,O75376,Q99653,Q13217,Q07812,O00410,P14373,O94813,P24468,Q9NY27,Q9BRG1,O95373 18 +Cilium organization 0.2762097900378123 0.4094207274249955 0.6822309311021808 1.0 0.9031246327816992 46 Q9Y5K8,Q14141,P50570,Q8WXH0,Q15555,P62820,Q9NVR5,O00471,Q96J42,A6NIH7,Q92538 11 +Mitochondrial transcription 0.4385185141216442 0.4085222753343096 0.6828902802166641 1.0 0.9031246327816992 8 Q9BSK2,Q96RR1 2 +Positive regulation of mitotic cell cycle phase transition 0.2957603305367176 0.4084923766127925 0.682912226224563 1.0 0.9031246327816992 31 Q9UJX2,Q9UJX3,P31350,P54652,P14635,Q9UJX4,Q96FF9,Q96DY7,P11802 9 +Response to oxygen containing compound 0.2290688798996484 0.4043995908982071 0.6859189009865696 1.0 0.905978655612364 255 Q99720,Q8TBX8,Q9HCD5,P17858,Q96RR1,Q86X55,O43823,Q9BSK2,O00410,Q9UQB8,Q96KQ7,Q6IQ22,O94813,Q86YS7,Q7L576,Q00535,Q6PD62,Q13126,Q9H7B4,Q96RT1,P17480,P50570,P00374,Q9UNS1,P23396,P21953,P38398,Q15648,P31751,P18887,P43490,P51812,P08574,P09601,Q9HCL2,P61586,Q86U42,Q15907,Q05086,P11802,Q96A49,Q99729,P80404,Q8TB36,O43865,Q9NVR5,O95831,O15228,P61981,P42345,P33121,P07196,Q9BZF1,P50416,Q8WTV0,P10620,P24941,P24468,Q9BRK5,Q9P0J0,Q12824 61 +Negative regulation of cell growth 0.2991745677162929 0.4035918414891004 0.6865128860827423 1.0 0.9062026680910874 28 O75414,O14681,O94813,Q9P0J0,Q9P265 5 +Negative regulation of response to external stimulus 0.2844271905046092 0.4033953077504417 0.6866574380717272 1.0 0.906206746659968 38 P04439,Q14166,P80404,Q96J02,P80303,Q9UMX5,P28070,Q9HCK8,Q96KB5,O94813,P55011,Q96QK1,O43657 13 +Peptidyl tyrosine dephosphorylation 0.3920366437172435 0.4015207977707599 0.6880367290229179 1.0 0.907639652567908 11 Q99956 1 +Vascular associated smooth muscle cell migration 0.4557103320950067 0.4013421330155821 0.6881682473497235 1.0 0.907639652567908 5 P61586,Q96N67 2 +Pyrimidine ribonucleotide metabolic process 0.4208380576981903 0.4007969985942383 0.6885695888343704 1.0 0.9079595078868116 9 O75414 1 +Negative regulation of phosphorylation 0.2638358024767421 0.4006277227132482 0.6886942317861409 1.0 0.9079595078868116 67 P42771,Q16625,Q8TBX8,Q9H7B4,Q8IXB1,Q9UHD1,O75376,Q99653,Q13217,Q07812,O00410,P14373,O94813,P24468,Q9NY27,Q9BRG1,O95373 17 +Neutral lipid biosynthetic process 0.4359085621400057 0.3997310821240561 0.6893545962780048 1.0 0.9086431159993618 8 Q9HCL2,P33121 2 +Nucleobase containing small molecule metabolic process 0.244936136514086 0.3990172891420463 0.6898804650709611 1.0 0.90896220881213 177 Q9NZ01,P85037,O75376,O60762,Q9NYU2,P00846,Q9NR45,Q02218,Q969T7,Q13126,Q9BRR6,O75414,P43490,Q53GQ0,Q9UKU0,Q8NFF5,P61586,Q9P2R7,P26572,Q9NVE7,Q8TB61,A8MXV4,Q9UJZ1,Q9BW91,P30520,P49902,O75964,P33121,P42345,P17812,P34949,Q9H773,O43252,O60313,P56134,O60725 36 +Vacuolar localization 0.333412663414673 0.3984765038979359 0.6902789745690001 1.0 0.9093002490415412 16 P51809,O95295,Q9BZG1,Q9H267,P09601 5 +Response to corticosteroid 0.3016250072083312 0.3953593805027516 0.6925776819752436 1.0 0.9102112523202994 26 O95831,P07196,Q9H7B4,O94813 4 +Negative regulation of mrna 3 end processing 0.4345633400536584 0.3952349010726467 0.6926695377071017 1.0 0.9102112523202994 8 P50750 1 +Trna processing 0.2829302778687891 0.3940610847427355 0.6935359411069304 1.0 0.910777947418708 38 Q99575,O75648,Q5KU26,Q7Z2T5,O95363,P62312,Q5VV42,Q9NNW5,Q08J23,Q9H974 10 +Regulation of chromatin organization 0.3235197668911546 0.3935447536707255 0.6939171762814047 1.0 0.9109084900120245 17 Q15047 1 +Regulation of catabolic process 0.2120142499914642 0.3914033611756323 0.6954991082403572 1.0 0.9122465584867516 287 Q9Y5K8,Q8TBX8,Q92804,P85037,Q14011,O75376,Q9Y371,Q96KQ7,A4D1P6,Q96HY6,Q9Y487,Q07820,Q7L8L6,Q96KB5,Q99570,Q13614,Q9UBQ0,Q9UL46,Q969T7,Q00535,Q8WU17,P62487,P31751,P16989,Q13868,Q96HJ9,Q92945,P14373,Q9NNW5,O75396,Q9NRR5,P09601,P60520,Q05086,P11802,O15269,Q9H2J4,Q6P6C2,Q9Y5A7,Q93050,P67809,Q9NQT5,Q99729,Q05639,Q07812,Q96J02,Q14145,P98175,O95831,P12235,Q08J23,Q96PU5,P51114,Q96B26,P42345,Q9HCE1,O75874,P50416,O00178,Q8WTV0,O95816,O15514,P54619,O43847,Q9P275,P35637,P24941,P46379,Q9P0J0 69 +Protein targeting 0.2588577774731573 0.3912230136165861 0.6956323988145714 1.0 0.9122465584867516 108 P61619,Q9UHD1,P57105,P49257,Q9Y371,Q5BJH7,Q10713,Q99595,Q99570,Q86YS7,O75381,Q96RT1,P31751,Q96RL7,Q12955,P62072,P55786,Q8TB36,O60830,O95831,O95429,P61981,P20645,P09132,P61009,Q9P275,P46379,Q99653,O60725,Q9P0J0,Q9Y5M8,O96008 32 +Fatty acid alpha oxidation 0.4525401396476461 0.3911107039546771 0.6957154089559683 1.0 0.9122465584867516 4 A1L0T0 1 +Regulation of actin filament based process 0.2637502138893791 0.3910621496062497 0.6957512974989426 1.0 0.9122465584867516 74 Q9Y5K6,O95429,Q13576,Q9UEY8,Q9Y613,Q9UQB8,P35611,Q08722,P14373,O94813,Q96F07,P61586 12 +Proteasome mediated ubiquitin dependent protein catabolic process 0.2498287468093648 0.3906064165785559 0.6960881819829221 1.0 0.9124495383226108 119 P46379,Q96PU5,Q9Y5A7,Q9Y5K6,Q92575,Q9UJX3,Q8IXB1,Q9H1A4,O43791,Q9BZK7,Q96J02,Q9UBV2,Q96HY6,Q14145,Q16763,Q9Y679 16 +Regulation of hormone metabolic process 0.4519304651588346 0.3896068116021267 0.696827314485158 1.0 0.9128560960477028 5 O75844,P16435,O60678 3 +Facultative heterochromatin assembly 0.3475856515564374 0.3891027164599765 0.6972001640759959 1.0 0.9128560960477028 14 Q15047 1 +Negative regulation of t cell proliferation 0.4514233490005326 0.3890553618635843 0.6972351932509906 1.0 0.9128560960477028 6 Q96IZ0,Q92990,Q96J02,P10644 4 +Grooming behavior 0.4003893575600228 0.3877239563794312 0.6982203253464305 1.0 0.9137486014646036 3 P07741,P00492 2 +Respiratory chain complex iii assembly 0.4508514841802571 0.3862865617086749 0.6992844518278667 1.0 0.9149542888907912 5 Q6DKK2,Q9BSK2 2 +Regulation of androgen receptor signaling pathway 0.4164899442040856 0.3857432988411094 0.6996867921000567 1.0 0.9150664846646068 9 O75376 1 +Negative regulation of organelle assembly 0.4316648909661762 0.3856294078433446 0.6997711504247455 1.0 0.9150664846646068 8 O75396,Q96KQ7,P50570 3 +Striated muscle cell proliferation 0.4414055897166832 0.3851971447400236 0.7000913586161155 1.0 0.9150664846646068 7 Q8NDZ4 1 +Endothelial cell proliferation 0.3387337709585739 0.3850136903386287 0.7002272725298007 1.0 0.9150664846646068 15 Q9H2J4,P09601,Q8WTV0,P24468 4 +Ire1 mediated unfolded protein response 0.43115111651233 0.3839385747354659 0.7010239748675509 1.0 0.9156030332352496 8 Q96HY6 1 +Copi coated vesicle budding 0.4499741086252168 0.3832698470939698 0.7015196939501356 1.0 0.9156030332352496 4 Q92538 1 +Cell cell junction assembly 0.2993189502444836 0.3830813556008897 0.7016594432010279 1.0 0.9156030332352496 26 Q16625,O43815,Q9Y2J2,P61586,O15228 5 +Neurotransmitter receptor transport 0.449768078771426 0.3829661126703322 0.701744890294649 1.0 0.9156030332352496 5 Q13277 1 +Mitochondrial cytochrome c oxidase assembly 0.440486920525954 0.3822774799740969 0.7022555569007058 1.0 0.9156623442918628 7 Q9GZY4,O43819 2 +Vitamin metabolic process 0.2972039517141618 0.3816251872270438 0.7027393990333548 1.0 0.9159203642335038 27 P00374,P38435,Q8N0U8,P41440,Q9Y5Z9,P78417 6 +Protein insertion into mitochondrial inner membrane 0.4300095139639955 0.3801944247732073 0.7038010974662077 1.0 0.9168333708307516 8 P62072 1 +Maintenance of protein location in cell 0.3183216190605438 0.3797677071809203 0.7041178555226746 1.0 0.9168333708307516 18 Q96RL7,Q12955,P24390 3 +Morphogenesis of an endothelium 0.4487885153940928 0.3796721783750099 0.704188774840635 1.0 0.9168333708307516 4 P61586 1 +Vesicle mediated transport in synapse 0.2906311484451194 0.3793990427591976 0.7043915612871914 1.0 0.9168333708307516 31 Q4J6C6,O00203,P50570,O00161,P56545,Q13277,Q96CW1,O95295,Q96QK1,Q13492,O14976,P35080,P20339,Q7L576,Q00535 15 +Triglyceride biosynthetic process 0.4392415216360782 0.3783364684726044 0.7051806573247847 1.0 0.916863667713126 7 Q9HCL2,P33121 2 +Positive regulation of glial cell differentiation 0.4477024664787963 0.3766729431762721 0.7064166725413239 1.0 0.9175395791361964 5 Q13547,P42345 2 +Reactive nitrogen species metabolic process 0.3366249165870223 0.375947769827523 0.7069557259283763 1.0 0.917867527421398 15 Q92945,Q08722,O43169,P50570 4 +Fat soluble vitamin metabolic process 0.4464827519069161 0.3738760753821291 0.7084965168404991 1.0 0.9183272597959382 6 P38435,Q9Y5Z9 2 +Cell junction organization 0.2568683032471451 0.3738243244486889 0.7085350211099797 1.0 0.9183272597959382 108 O15031,Q16625,Q9Y4F1,Q15555,Q12955,Q9UQB8,Q9Y2J2,Q13614,Q9BRK5,P41440,Q05086,O15228 12 +Regulation of cell migration involved in sprouting angiogenesis 0.4466611201246648 0.3732568309185408 0.708957302419797 1.0 0.9184187015775976 4 P09601 1 +Peptidyl serine modification 0.2625531136191162 0.3726580192390553 0.7094029850785062 1.0 0.9188102552391652 54 O95429,Q9H7B4,P42345,P31751,Q9HAW4,Q07812,Q96N67,Q13131,P78362,P51812,P24941,P35080,P48729,Q7Z4H8,Q00535,Q13418 16 +Positive regulation of intrinsic apoptotic signaling pathway 0.3272989550064836 0.3711856052771826 0.7104992938308206 1.0 0.9200441633879596 16 P63241,Q13794,P23396,Q07812,Q07820,Q9NYF8,O00429,P51572 8 +Vesicle mediated transport between endosomal compartments 0.3268711747523713 0.3693127723694369 0.7118946064623479 1.0 0.9216646824975344 16 A4D1P6,O94832,Q13614 3 +Protein localization to cell surface 0.3179594593877219 0.3680025371943359 0.712871342340069 1.0 0.9221837275909698 17 Q15907,Q96PU5,Q13277,Q92538 4 +Negative regulation of dna templated transcription elongation 0.4108760527819898 0.3667215874189626 0.7138267023465399 1.0 0.9228605156875752 9 Q9H3P2,O94992,Q8IXH7,Q8WX92 4 +Microtubule anchoring at microtubule organizing center 0.3935756002595757 0.3646971258269778 0.7153375043189112 1.0 0.9232824285637412 3 Q14203,Q8TD16 2 +Transport of virus 0.4435600168077153 0.3642031457005626 0.7157063181427445 1.0 0.9232824285637412 5 P52292,P42566,O00505 3 +Negative regulation of transmembrane transport 0.3145605951364092 0.3623970943204066 0.7170553105449926 1.0 0.9247949102780798 18 Q96PU5,Q12955,P78417,P31751 4 +Polyol catabolic process 0.4423021795510319 0.3612597234036689 0.7179052995094224 1.0 0.9254710705700596 6 Q13614 1 +Dna recombination 0.2602398054898731 0.3607757838175942 0.7182670670333469 1.0 0.9254710705700596 98 P52292,P25205,P46063,Q9UQ84,Q96B01,Q9NY27,Q9BXW9,Q9UNS1,Q86V81,P18887,Q9NRR5,Q68CP9,Q9NQT5,Q9BRT9,Q15631,O14757,Q9UBU8,Q96T76,P35637,O96028,P49959,Q96SB8 22 +Negative regulation of histone modification 0.3244015551383811 0.3585968854296196 0.7198966771075757 1.0 0.926279100136976 16 Q9NY27,P38398,O95071,Q12824 4 +Histone h4 k20 methylation 0.4414680252974311 0.3579834404099404 0.720355706092443 1.0 0.926279100136976 5 Q14166,O96028 2 +Ribose phosphate biosynthetic process 0.2607410540719644 0.3573316691151118 0.7208435243406439 1.0 0.926279100136976 78 Q9UKU0,O75964,P33121,O75414,Q9NVE7,P17812,O43252,P00846,Q53GQ0,P56134,P30520 11 +Regulation of lipase activity 0.4080122570734361 0.3572029599310351 0.7209398701742982 1.0 0.926279100136976 9 P40616,P61586 2 +Microtubule polymerization 0.2970558584914504 0.3560356293596836 0.7218138827771197 1.0 0.926745222657715 24 Q16625,P63000,P23396,Q14203,Q15691,Q96P70,Q96CW5,Q9ULW0 8 +Protein localization to microtubule 0.4224577441545456 0.3558822744167451 0.7219287308766829 1.0 0.926745222657715 8 Q15555,Q15691,P29372 3 +Negative regulation of leukocyte proliferation 0.4222175066490979 0.3551220823347836 0.72249813411819 1.0 0.9270862699811768 8 Q92990,Q96J02,P10644 3 +Maintenance of protein location 0.2938582236133542 0.3548400076397723 0.7227094543744796 1.0 0.9270862699811768 26 Q96RL7,Q12955,P24390,Q9UN86,Q14145,O94901,O43731 7 +Diencephalon development 0.4316675744686205 0.3547999887287381 0.7227394368226658 1.0 0.9270862699811768 7 Q02218 1 +Neurogenesis 0.231438331350408 0.3543582635034737 0.7230704087262612 1.0 0.9271805428675508 239 O15031,Q8WUJ1,Q15555,Q86X55,Q9UQB8,Q96KQ7,Q13547,Q13614,O94813,O14976,P41440,Q02218,O94901,Q13418,Q9P265,Q9UBB6,P00374,P31751,Q12955,Q32P28,Q9Y2J2,P61586,Q05086,Q9Y4F1,Q8WXH0,Q13277,Q07812,Q96N67,Q9NQC3,Q96F07,Q96PU5,P42345,P07196,O43815,Q13555,Q16706,Q9BUP0,P55209 38 +Positive regulation of actin filament bundle assembly 0.3527147688553157 0.3538183530306101 0.723475018348489 1.0 0.9274726771143528 13 O95429,Q08722,Q9Y613,P61586 4 +Actin filament based transport 0.4394007315675868 0.3526292833602238 0.7243663811717944 1.0 0.9276960283538236 6 Q8WXH0 1 +Intestinal hexose absorption 0.341226078494973 0.3517639312780473 0.725015310521445 1.0 0.9276960283538236 2 Q14651 1 +Regulation of microvillus length 0.341226078494973 0.3517639312780473 0.725015310521445 1.0 0.9276960283538236 2 Q14651 1 +Negative regulation of protein localization to nucleus 0.4392824524773232 0.3515421142477347 0.7251816834083122 1.0 0.9276960283538236 5 Q99653 1 +Regulation of sodium ion transport 0.322638587937255 0.3510487020542596 0.7255518115681203 1.0 0.9276960283538236 16 Q96PU5,P50570,Q9UHD1,Q12955,O43865,Q99653 6 +Regulation of cell projection organization 0.2574158426639751 0.3508272557573949 0.7257179481148772 1.0 0.9276960283538236 102 O15031,Q96PU5,Q16625,P07196,Q8WXH0,Q15555,Q86X55,Q32P28,Q9NQC3,Q9UQB8,Q13555,O94813,P61586,Q05086,Q9P265 15 +Cytochrome complex assembly 0.3516394220699437 0.3496932984712554 0.72656888357574 1.0 0.9284660419282248 13 O43819,Q15070,Q9BSK2,P53701,Q9GZY4 5 +Regulation of lipid kinase activity 0.4296385831327703 0.3486231927546356 0.7273722135756944 1.0 0.928596399173888 7 Q99570,A4D1P6,Q8TBX8 3 +Cellular response to virus 0.3115036141374041 0.3485919384002137 0.7273956807765485 1.0 0.928596399173888 18 P63241,Q9NUD5,Q07812,Q9H078,Q92538,O43657 6 +Positive regulation of intracellular signal transduction 0.2398109744804789 0.3468909501169607 0.7286732457614213 1.0 0.9293333443205748 124 O95429,Q96RT1,Q13794,Q96EE3,Q15555,Q9NUD5,Q9UMX5,Q9Y3E0,P14373,P62841,P61586,P09601,O43657,Q05086,Q13418 15 +Cortical cytoskeleton organization 0.3009126800281591 0.3462651201893693 0.7291434791386664 1.0 0.9293333443205748 22 P63000,Q9Y613,P11171,Q9Y2J2,Q14651,P61586,Q00535,P43034 8 +Ventricular septum morphogenesis 0.4368831908839807 0.3444521371273119 0.7305062851594908 1.0 0.9305275925097828 4 O94813 1 +Dna geometric change 0.2595106651625645 0.3431744100184331 0.7314672548665258 1.0 0.9313063205866462 51 P40938,Q96RR1,P49736,P25205,P46063,Q2NKX8,Q9BRX5,Q9BRT9,P49959,Q96S55 10 +Negative regulation of protein modification process 0.2511878083151446 0.3431531835011836 0.7314832227459005 1.0 0.9313063205866462 111 Q16625,Q9UHD1,O00410,Q96KB5,O94813,Q9NY27,Q9BRG1,Q00535,Q9H7B4,O95071,P23396,P38398,P18887,Q32P28,Q6DKJ4,P14373,O60566,Q13217,Q07812,P62841,O95373,Q9BX68,P42771,P61981,Q8IXB1,P24468,Q99653,O95816,Q12824 29 +Positive regulation of mitochondrial membrane potential 0.4364003416053075 0.3430594144788292 0.7315537629085238 1.0 0.9313063205866462 4 P31751 1 +Positive regulation of brown fat cell differentiation 0.3386312033733382 0.3421875807276516 0.7322097308658821 1.0 0.931586005149323 2 Q92766 1 +Forebrain generation of neurons 0.4359296158937148 0.341774668607248 0.7325204743876419 1.0 0.9317962984367024 5 Q02218 1 +Ribose phosphate metabolic process 0.2399088364384625 0.3405340244434798 0.7334544043580162 1.0 0.9326139170935792 136 Q9NZ01,P85037,O75376,P00846,Q02218,Q9BRR6,O75414,Q9UKU0,Q53GQ0,P61586,Q9P2R7,Q9NVE7,Q8TB61,A8MXV4,Q9UJZ1,Q9BW91,P30520,P49902,O75964,P33121,P17812,O43252,P56134,O60313 24 +Dna replication initiation 0.2924744376752743 0.3401589671925919 0.7337368170525482 1.0 0.9327878646633508 25 P49427,Q14181,P49736,Q9Y619,P25205,Q9BRX5,P33993,Q9Y5N6,P24941,Q13416,Q96S55,Q9UBD5 12 +Regulation of postsynaptic membrane neurotransmitter receptor levels 0.4265519106061703 0.3393331221864399 0.7343587933884284 1.0 0.9330657222522474 7 Q13277,Q96RT1 2 +Regulation of microtubule polymerization or depolymerization 0.2900542453831069 0.3358813780462896 0.7369603202601178 1.0 0.9350651094154953 26 Q16625,Q8WWK9,Q8IX90,P63000,P29372,P23396,Q15555,Q14203,P36405,Q15691,Q9ULW0 11 +Regulation of cell cell adhesion 0.2688583850004016 0.3356514115813019 0.7371337500075321 1.0 0.9350651094154953 43 P30825,Q9NUQ9,P04439,Q5JRA6,P23396,Q12955,Q96J02,Q9HCM4,Q08722,P55196,P41440,Q9HCL2,P61586 13 +Cellular response to alcohol 0.3263302106024149 0.3333001084005734 0.7389077575671168 1.0 0.9359961659452062 15 O95831,O43823 2 +Protein complex oligomerization 0.2569830528559191 0.3328028142384022 0.7392831337685253 1.0 0.9361232960903682 58 Q15758,Q99720,Q8TDW0,Q96RR1 4 +Protein modification by small protein conjugation 0.240994465627583 0.3319629236994494 0.7399172555421734 1.0 0.9364780148260334 163 Q96T88,Q96HY6,Q14527,P52888,Q9C0C9,Q9UJX3,Q9H1A4,Q9UBV2,P14373,P50750,Q05086,Q9Y5A7,Q96DX4,O75155,P55786,O60566,Q6P2C8,Q96J02,P62841,Q14145,Q16763,Q96PU5,Q13616,O43791,Q99653,Q96DY7 26 +Regulation of vasoconstriction 0.3833579159506201 0.3314506601644021 0.7403041040443818 1.0 0.9364780148260334 3 P61586 1 +Sensory organ morphogenesis 0.2977353686492038 0.3313327337902257 0.7403931683728568 1.0 0.9364780148260334 22 Q8IZL8,Q16706,Q15555,Q13547 4 +Regulation of supramolecular fiber organization 0.2580917654055153 0.3303312975312278 0.7411496469439116 1.0 0.936743061149528 83 Q16625,Q9NUQ9,O60925,Q14203,Q9UQB8,O94813,Q9ULW0,Q7L576,Q9BPX3,P63000,P62993,P29372,P23396,P35611,P14373,Q08722,P61586,O15145,P60981,Q15691,Q96F07,O95429,Q8WWK9,Q9UEY8,Q9UHB6,Q9Y613,P42345,P53367 28 +Response to endoplasmic reticulum stress 0.2582226914707878 0.3301524405503327 0.7412847807301923 1.0 0.936743061149528 85 P46379,Q8IXB1,Q92575,Q13794,Q9UM00,Q7Z2K6,Q9UBV2,Q96HY6,Q9NYU2,Q9Y5P4,O95831,P41440,Q9Y679 13 +Regulation of viral process 0.267536181800769 0.3278217205817383 0.7430464634008087 1.0 0.937604005189747 43 Q15047 1 +3 utr mediated mrna stabilization 0.4133144896676486 0.3275439555795651 0.7432565029964433 1.0 0.9376331544299362 8 P16989 1 +Regulation of protein stability 0.2534871874682136 0.3272764705697661 0.7434587871576488 1.0 0.9376958796950008 104 Q9H2J4,Q96PU5,O95429,Q9BXJ9,Q32P28,Q9Y371,Q9UBV2,Q9NQC3,Q96HY6,Q969V3,P46379,Q9HBM6,P41440,Q96K76,P83436 15 +Response to estrogen 0.3453745244152091 0.3261758593743082 0.7442913049098114 1.0 0.9380417723769224 13 Q15291,O15164,P38398,P21266,Q8IZL8,P09601 6 +Purine ribonucleoside metabolic process 0.4122618611999634 0.3243612249866143 0.7456645721130322 1.0 0.9388446968111628 8 Q13126,O60725 2 +Ribonucleoside metabolic process 0.4122618611999634 0.3243612249866143 0.7456645721130322 1.0 0.9388446968111628 8 Q13126,O60725 2 +Positive regulation of transferase activity 0.2573945279395464 0.3237250303490176 0.7461462189819523 1.0 0.9388446968111628 86 Q8NDZ4,Q13432,Q9BRX5,Q96M27,Q99570,Q9ULW0,P23396,P61586,Q86U42,Q96A49,Q05639,P14635,Q9NQS7,Q9BRT9,Q16763,P40938,P42345,P33121,Q9HAW4,Q9BZF1,P54619,P49959 22 +Leukocyte degranulation 0.3975725245694016 0.3236021411645756 0.7462392667129667 1.0 0.9388446968111628 9 P09601 1 +Positive regulation of stress fiber assembly 0.3576737501935549 0.3235632891081971 0.7462686850081861 1.0 0.9388446968111628 12 O95429,Q08722,Q9Y613,P61586 4 +Regulation of histone ubiquitination 0.3825840804489505 0.3233485957016176 0.7464312548600103 1.0 0.9388648377445956 10 Q6PD62,P50750 2 +Odontogenesis 0.357368205610696 0.32248844349173 0.7470826912766197 1.0 0.9393153523686018 12 Q13547,Q13586,P61586 3 +Actin filament organization 0.2566042988658578 0.3208432879816063 0.748329153099974 1.0 0.940605065166362 92 P49006,Q9Y5K6,O95429,Q9UEY8,Q13576,Q9NUQ9,Q9Y613,O94832,P29966,Q9UQB8,P35611,P14373,O94813,Q96F07,Q08722,P61586 16 +G quadruplex dna unwinding 0.4284323271665095 0.3204937686872804 0.7485940533276925 1.0 0.9406617311920747 4 P22626,Q9H2U1,Q08211 3 +Negative regulation of protein secretion 0.4106248503912826 0.3194449590532138 0.7493891228239529 1.0 0.9412915138843612 8 P30040,Q16850,P17858,Q6WKZ4 4 +Cellular response to dsrna 0.3960211914228082 0.3187604176045618 0.749908195841946 1.0 0.9413970751610572 9 P41440 1 +Central nervous system neuron development 0.3811715375770647 0.3187511423438295 0.7499152298504506 1.0 0.9413970751610572 10 P00492,O94813,O14949,Q02218,Q00535,P43034 6 +Cellular oxidant detoxification 0.2892847128241824 0.3185589509222077 0.7500609852672551 1.0 0.9413970751610572 24 P28161,P00374,P10620,Q8TED1,Q6DKJ4,Q9Y5Z9,P78417 7 +Leukocyte mediated immunity 0.265887777882782 0.3182181051170491 0.7503195001346383 1.0 0.9415099576559364 43 P09601,Q9UQ84 2 +Negative regulation of protein localization 0.2675620220590277 0.3166107613475316 0.7515389692019168 1.0 0.9421445473008764 41 P30040,P17858,Q9UHD1,P49257,Q10713,P31689,Q00535,Q16850,Q9Y385,Q00610,Q13492,P41240,Q6WKZ4,Q99728,Q96PU5,O95429,Q96CW1,P46060,Q99653,Q96QK1 20 +Transition metal ion transport 0.3140031543441152 0.3153353966463892 0.7525070122426212 1.0 0.9428046001224782 16 Q9HD20,P98194,P50570,Q9HC07,Q15907 5 +Regulation of receptor catabolic process 0.4256349411357192 0.3127616904923332 0.7544617227376986 1.0 0.9439612882534564 4 Q13614 1 +Regulation of vacuole organization 0.3658484273007344 0.308553506812839 0.757661192297332 1.0 0.9459320985883276 11 O75396,Q96KQ7,Q9Y371 3 +Locomotor rhythm 0.4238228525225775 0.3078068669875331 0.7582292960242252 1.0 0.94614971089392 4 O75376 1 +Negative regulation of plasma membrane bounded cell projection assembly 0.4236826900595247 0.3077420961765357 0.7582785850342468 1.0 0.94614971089392 6 P50570,O94813 2 +Vitamin transmembrane transport 0.4154774144330823 0.3070913614186994 0.7587738328276017 1.0 0.9464581916734256 7 P41440 1 +Nucleoside phosphate biosynthetic process 0.2548181839382686 0.3067370602950098 0.7590435186497111 1.0 0.9464581916734256 91 Q9UKU0,O75964,P33121,O75414,Q9NVE7,P17812,P43490,O43252,P00846,Q53GQ0,Q8NFF5,P56134,P30520 13 +Endoplasmic reticulum calcium ion homeostasis 0.390904641506487 0.3030776409898887 0.761830693181411 1.0 0.9483917235257476 9 Q9UM00,P55061,Q07812 3 +Metaphase anaphase transition of cell cycle 0.2914531358531973 0.3029125186804006 0.7619565307712572 1.0 0.9483917235257476 22 Q9UJX2,Q9UJX3,Q9H1A4,P14635,Q9Y6G9,O60566,O43684,O43264,P50748,Q9UJX4,Q5JVF3 11 +Regulation of t cell activation 0.2735551304719534 0.3017584145982395 0.7628362342240798 1.0 0.9489973971867118 33 P30825,Q9BXW9,Q9NUQ9,P23396,Q96J02,O96005,Q08722,Q9HCL2,P61586 9 +Membrane depolarization 0.390433953768156 0.3016572418266969 0.7629133667073176 1.0 0.9489973971867118 9 Q96PU5 1 +Negative regulation of signaling receptor activity 0.4214511516182145 0.3016339883070782 0.7629310951469819 1.0 0.9489973971867118 6 Q9BRG1,Q96FZ7,Q9UNH7,Q99816 4 +Glucose metabolic process 0.2528825924042546 0.3008840001887108 0.7635029513116947 1.0 0.9490281140535184 51 P50416,P11310,Q9BRR6,Q92520 4 +Glial cell migration 0.350885125379708 0.3001556008099743 0.7640584698867348 1.0 0.9494778968175408 12 Q96G23,Q8WXH0,P46109,Q9NQC3,O94901,Q00535,P43034 7 +Transcription elongation from rna polymerase ii promoter 0.2765716823858247 0.2985187124313666 0.7653072963595011 1.0 0.9499660096618102 29 Q6PD62,P55199,P35269,Q8IXH7,Q8WX92,P50750 6 +Response to light stimulus 0.255207258263063 0.298204035671538 0.7655474418239299 1.0 0.9499660096618102 49 Q96K76,Q13432,Q9BRK5 3 +Alcohol biosynthetic process 0.2684117485106593 0.2981214182402831 0.7656104950250102 1.0 0.9499660096618102 36 Q14739,Q15392,P00374,P56937,O75845 5 +Cellular response to acid chemical 0.3374329991936692 0.2976681878550073 0.7659564257560416 1.0 0.9499660096618102 13 Q9UQB8,P42345,Q99729 3 +Cleavage involved in rrna processing 0.2973478957516919 0.2975599744652556 0.7660390271606254 1.0 0.9499660096618102 19 Q96B26,Q9NQT5 2 +Positive regulation of intracellular protein transport 0.2507941555136149 0.2973764082538969 0.7661791529354494 1.0 0.9499660096618102 52 Q9Y282,P31751,Q9UHD1,Q92688,P55786,Q99653,Q12955,Q9Y371,Q9P275,Q86YS7 10 +Positive regulation of phospholipid biosynthetic process 0.4199554036557985 0.2973755587287205 0.7661798014406265 1.0 0.9499660096618102 4 Q99653 1 +Regulation of chromatin binding 0.4196914646934763 0.2964998069716056 0.7668484143574146 1.0 0.9499660096618102 5 Q71SY5,O60341 2 +Positive regulation of plasma membrane bounded cell projection assembly 0.2899236409983147 0.2962206952513264 0.7670615451608693 1.0 0.9499660096618102 22 Q16625,P42345,P50570,Q15555,Q7L576 5 +Peptidyl lysine modification 0.2496253666346151 0.2947120668238314 0.7682138443963062 1.0 0.9502177808848692 103 Q96AY3,Q9H7B4,Q9UBU8,Q03164,Q15047,P14373,P46379,Q86UY6,Q9UKN8,Q12824,Q9P265 11 +Endocytosis 0.2521284252298372 0.2943869110764097 0.768462267469497 1.0 0.950277322194929 96 Q5JRA6,P57105,P51809,Q13432,O60749,Q13614,O14976,Q8NC96,P41440,Q00535,O15126,P63000,P50570,O95782,Q5KU26,Q9BZG1,Q05086,Q13492,Q14C86,Q9Y5K6,Q96PU5,P20645,Q96CW1,Q8WTV0,P62820,Q96D71,P63010 27 +Positive regulation of leukocyte cell cell adhesion 0.2916943221103828 0.293590987443243 0.7690704634188155 1.0 0.950277322194929 21 P30825,Q9NUQ9,P23396,Q08722,Q9HCL2,P61586 6 +Carbohydrate derivative biosynthetic process 0.2367364722876584 0.2925842460450158 0.7698399569054288 1.0 0.950277322194929 159 Q9NZ01,O60762,Q9NYU2,P00846,Q9NR45,O60502,Q13126,O75414,O95782,Q96AA3,Q9HC07,Q9UKU0,Q53GQ0,O60476,P26572,Q9NVE7,Q8TB61,Q13724,P83436,P30520,O75964,P33121,P17812,P34949,Q7LGA3,O43252,Q16706,P56134,Q99653 29 +Germ cell development 0.2715709053742925 0.2920195470760129 0.7702716786309369 1.0 0.950277322194929 33 Q9BQA1,Q9GZT3,P42345,P54652,Q96SI9,A0AVF1,Q01085,Q07812,Q96KQ7,Q96MU7,Q9Y385,Q08J23,P43246,P17252 14 +Vascular associated smooth muscle contraction 0.3703148174742016 0.2913904904468468 0.7707526866811636 1.0 0.950277322194929 3 P61586 1 +Regulation of myelination 0.4008558655188233 0.2909696101573054 0.7710745619720423 1.0 0.950277322194929 8 Q96P11,P42345,Q13614,Q7L576 4 +Interleukin 2 production 0.4007586360303347 0.290693761518644 0.7712855432531365 1.0 0.950277322194929 8 Q9UJZ1,P14373 2 +Regulation of smad protein signal transduction 0.3698896820246597 0.2901316535923314 0.7717155206905175 1.0 0.950277322194929 3 Q8N1F7,P09874 2 +Regulation of cell development 0.2498885055700107 0.2899536465025359 0.7718516996169438 1.0 0.950277322194929 73 O15031,Q13418,P07196,Q96N67,Q9NQC3,Q9UQB8,P35611,Q16706,O94813,P55209,Q9P265 11 +Zinc ion homeostasis 0.4171797636942622 0.2898082388477179 0.771962944550219 1.0 0.950277322194929 5 P35670,Q8TAD4 2 +Mesoderm development 0.3600107021678566 0.2896323279258702 0.7720975324433197 1.0 0.950277322194929 11 Q14696,Q8WUM0,Q16881,P17252,Q9HCM4 5 +Cell fate commitment 0.290621234969761 0.2890319855505958 0.7725569007057598 1.0 0.950277322194929 21 Q6PD62,P42345,Q96N67,Q96KQ7,P61586 5 +Positive regulation of rna metabolic process 0.2135422205705065 0.2888912229941783 0.7726646205385899 1.0 0.950277322194929 325 Q8NB78,Q96T88,Q92804,Q03164,Q14011,P85037,Q86X55,Q9UH62,Q9BRX5,Q96HY6,Q13547,Q8IZL8,P41440,Q969T7,Q13418,Q9H7B4,P17480,Q86V81,Q8IWA0,Q9BZK7,Q9Y2X0,Q13868,P43490,P14373,P50750,P98179,Q05086,Q9NQT5,O75155,Q9BRT9,O60244,Q96B26,Q99417,Q71SY5,Q9Y613,P35269,Q15427,O15514,Q8WUB8,Q9BXJ9,Q12824 41 +Neuronal action potential 0.4165824772563626 0.2884398399583194 0.7730100750683715 1.0 0.9502787451329856 4 Q12955 1 +Response to xenobiotic stimulus 0.2481196968436531 0.2873411093186799 0.7738511484968063 1.0 0.9510522606161464 68 P33121,P18887,P50416,P17812,Q96KQ7,P50750,P09601,Q96K76,P61586,P11802,P78417,O15228 12 +Intracellular estrogen receptor signaling pathway 0.2921764833111512 0.2867103510906099 0.7743341111748707 1.0 0.9510522606161464 20 Q96HY6,Q86X55 2 +Receptor internalization 0.2946792081726015 0.2865660610179636 0.7744446043309114 1.0 0.9510522606161464 19 P41440 1 +Intracellular transport of virus 0.4156205185577216 0.2859193250640502 0.7749399120848828 1.0 0.9512695500371434 4 P52292,O00505 2 +Regulation of cell differentiation 0.2315424531137214 0.2856051369810352 0.7751805685388578 1.0 0.9512695500371434 183 O15031,Q8WUJ1,Q86X55,Q8N4Q0,O96005,Q9UQB8,Q13547,O94813,Q9BYT8,Q9P265,Q13418,Q9BXW9,Q6PD62,Q9H6W3,P35611,P51812,P50750,P61586,Q96A49,Q96N67,Q96J02,Q9NQC3,Q14145,Q9C0E8,P07196,Q16706,P55209 27 +Fibroblast migration 0.3138337363282567 0.2853318968011892 0.7753898779713924 1.0 0.9512695500371434 15 O95429 1 +Microtubule organizing center localization 0.3463435304455916 0.2850602131832984 0.7755980112151108 1.0 0.9512695500371434 12 Q8WXH0,O94901 2 +Organelle fusion 0.2560263821711316 0.2831538898631928 0.7770588729974135 1.0 0.95229131049446 46 P31751,P51809,O14653,Q13277,O95249,Q07812,O43752,Q9BZG1,O60313,O75396,Q86YS7,Q9UJZ1 12 +Apical junction assembly 0.2958913798729487 0.2827216727568032 0.7773902013114988 1.0 0.95229131049446 18 Q16625,O43815,P61586 3 +Negative regulation of response to biotic stimulus 0.3130901498141982 0.2826153978092287 0.7774716755988176 1.0 0.95229131049446 15 Q14166,Q96J02,O43657 3 +Inner cell mass cell proliferation 0.4062445441917695 0.2815647023395285 0.7782773089847221 1.0 0.952644274779738 7 O75312,Q9BRT9,O14757 3 +Positive regulation of endocytosis 0.2955923290046396 0.2815387169640531 0.778297236607784 1.0 0.952644274779738 18 P41440 1 +Negative regulation of transcription from rna polymerase ii promoter in response to stress 0.3666450356911065 0.2806244945308357 0.7789984267433145 1.0 0.952644274779738 3 P55061,O95817 2 +Regulation of cellular amide metabolic process 0.2341730243410653 0.2805577305723186 0.7790496404063569 1.0 0.952644274779738 170 O15031,P60228,Q14011,Q71RC2,Q13131,Q10713,Q8TEQ6,Q7L576,Q969T7,P05198,O15372,Q8WU17,P62487,P31751,Q16799,P00374,P23396,P61221,P16989,Q13868,Q92945,P51812,P61586,P98179,P26196,P67809,Q9NQT5,Q15024,P55010,Q13217,O15371,Q96C86,Q9NQC3,Q9Y6M1,Q13492,P23588,Q9Y6E2,Q96P11,Q96B26,P51114,P42345,Q9HCE1,Q567V2,O15514,O95453,P19525,P49458,P62263 48 +Positive regulation of fatty acid metabolic process 0.4134586553080085 0.2803005146704992 0.7792469559547031 1.0 0.952644274779738 4 P50416 1 +Postsynaptic signal transduction 0.4130688547156065 0.2792941605362845 0.7800190872785691 1.0 0.953042584990752 4 P52292,P46109 2 +Protein k48 linked deubiquitination 0.3960668198845118 0.2775636217266453 0.7813473608324586 1.0 0.9541063781984446 8 P45974,Q99496,Q9H8M7,Q96FW1,Q93009 5 +Response to camp 0.3816580071558175 0.2758779155409401 0.7826418367591637 1.0 0.9549721154817528 9 Q86X55 1 +Negative regulation of protein metabolic process 0.2188727218279665 0.2745852514054309 0.7836348986207526 1.0 0.9551846283496608 253 Q16625,Q15392,Q9UHD1,P60228,Q14011,O60925,O00410,Q96HY6,Q10713,O94813,Q96KB5,Q9C0C9,Q9BRG1,Q9NY27,Q969T7,Q00535,P05198,Q8WU17,O15372,Q9H7B4,P78318,P62487,O95071,Q16799,P00374,P23396,P38398,P18887,Q32P28,Q13868,Q6DKJ4,Q92945,P51812,P14373,Q96K76,P60520,Q9H2J4,P67809,Q9NQT5,O60566,Q13217,Q07812,Q9NQC3,Q9Y6M1,Q13492,P62841,O95373,Q9BX68,P42771,P61981,Q8IXB1,Q96B26,P51114,Q9HCE1,O15514,P24468,P46379,Q99653,O95816,Q12824 60 +Establishment of mitochondrion localization 0.3946532812837955 0.2736779010547395 0.7843321619929509 1.0 0.9553623447155782 8 O60313,Q9UH62,P07196 3 +Regulation of translation in response to endoplasmic reticulum stress 0.410522646120837 0.2727717346294049 0.7850286883932591 1.0 0.9557000718067687 4 Q13217 1 +Chromosome organization 0.2176923366047444 0.2725730352444738 0.7851814420573349 1.0 0.95570441151801 354 P55209,Q8NB78,Q96T88,Q96EE3,Q96RR1,Q03164,O75376,Q86X55,O43823,P25205,Q9BRX5,Q96KQ7,Q15047,Q9UQ84,Q14527,Q13547,P41440,Q6IPU0,O94901,Q6PD62,Q9BXW9,Q9H7B4,Q9UJX3,Q9H1A4,P18887,Q9BZK7,Q96ES7,Q9BTE3,Q9H6W3,Q9Y2K7,P14373,Q9H9B1,Q15059,Q96DB5,Q68CP9,Q96JM7,P14635,O60566,Q9BRT9,O95831,Q8N3U4,Q15021,P54652,Q9NRG0,Q2NKX8,P46379,Q12824 47 +Negative regulation of jnk cascade 0.4099409725346679 0.2712218861486597 0.7862203809271922 1.0 0.956423805586706 6 O75376,P31689,Q96J02 3 +Neurotransmitter receptor transport endosome to postsynaptic membrane 0.3630759247241996 0.2703738284790875 0.7868726724089088 1.0 0.957035568530752 3 P61006,Q96QK1 2 +Sensory organ development 0.2489170798178037 0.2693818227028826 0.7876358727133392 1.0 0.957636540076495 50 Q15293,Q92688,P49736,Q15555,O43819,Q15648,Q07812,P20020,P33993,O95140,Q13547,P83731,Q16706,O95487,Q14651,Q8IZL8,Q9NP72,P43034 18 +Methylation 0.2433295360794115 0.2692419056964569 0.7877435343851988 1.0 0.957636540076495 108 Q8NB78,Q9H7B4,Q03164,Q15047,Q12824 5 +Regulation of small molecule metabolic process 0.2474979678939307 0.2690822726019451 0.7878663719110168 1.0 0.957636540076495 51 P11310,Q13794,P85037,O75376,P50416,Q92520,Q9BYT8 7 +L amino acid transport 0.3411240875348602 0.2682858792214355 0.7884792746852598 1.0 0.9577039042950146 12 P30825,O60831,Q15758 3 +Blastocyst development 0.2639073766698654 0.2682150806894441 0.7885337674400423 1.0 0.9577039042950146 35 Q6PD62,P31350,O75312,Q7KZ85,Q9BZK7,Q6W2J9,Q9NQC3,O95140,Q9BRT9,P49321,Q13895,O14757,Q12824 13 +Positive regulation of carbohydrate metabolic process 0.4011801279663025 0.2681054052415151 0.7886181853194196 1.0 0.9577039042950146 7 Q13794 1 +Glycolytic process through fructose 6 phosphate 0.3786456377801881 0.2673426130376942 0.7892053798750509 1.0 0.9577460331447836 9 P85037,Q9BRR6 2 +Regulation of cytoskeleton organization 0.2395429624677762 0.2662448593489832 0.7900506366201536 1.0 0.9579755237581998 113 Q16625,Q9NUQ9,Q15555,Q14203,Q13131,Q9UQB8,O94813,Q9ULW0,Q7L576,Q00535,Q9BPX3,P63000,P62993,P29372,P23396,P38398,P35611,P14373,Q08722,P61586,O15145,P60981,Q15691,Q96F07,Q13576,Q9Y5K6,O95429,Q8WWK9,Q9UEY8,Q9UHB6,Q8IX90,Q9Y613,P42345,P53367 34 +L alpha amino acid transmembrane transport 0.3524050077174159 0.2660377621729116 0.7902101266130472 1.0 0.9579755237581998 11 P30825,O60831,Q15758 3 +Regulation of potassium ion transmembrane transporter activity 0.3780515303927102 0.265678493810649 0.7904868277530197 1.0 0.9579755237581998 9 Q96PU5 1 +Positive regulation of chromosome condensation 0.4070890239608941 0.2638022073373688 0.7919323336002213 1.0 0.9585305502804922 5 Q9NTJ3,Q15021 2 +Positive regulation of cell morphogenesis involved in differentiation 0.2756119598022454 0.2636116201760088 0.7920792035658353 1.0 0.9585305502804922 25 Q9UQB8 1 +Regulation of protein localization to membrane 0.2588030275233213 0.2633361659472174 0.7922914866898543 1.0 0.9585305502804922 39 P31751,Q9UHD1,P98194,Q99653,Q12955,Q13277,Q96CW1,Q13492,P63010,Q86YS7,Q00535 11 +Histone deacetylation 0.2680214859268263 0.2626438717584505 0.7928250820223204 1.0 0.9588139466556512 30 O43823,Q96ES7,Q9BZK7,Q9UBU8 4 +Negative regulation of peptidyl lysine acetylation 0.4062802972199687 0.26194271642367 0.7933656061064005 1.0 0.9588397792468342 6 Q9BX68 1 +Response to abiotic stimulus 0.2281572070111255 0.2600241117266951 0.7948451746708021 1.0 0.959084232236044 200 P11310,Q6P6C2,Q13794,O95831,Q96SI9,P55786,Q13432,Q15555,P16989,Q9Y487,Q8TDW0,P00846,Q9BRK5,P09601,Q96K76,P30520,P30519 17 +Mitotic chromosome condensation 0.3379755298623912 0.258469548909668 0.7960445471108939 1.0 0.9597676929760314 12 Q9NTJ3,O43823,Q96FF9,Q15021 4 +Negative regulation of carbohydrate metabolic process 0.375068951634443 0.2574207263758448 0.7968540045339272 1.0 0.960028165261316 9 O75376,Q92520 2 +Negative regulation of establishment of protein localization 0.2727105946676246 0.2573526662558328 0.7969065393505652 1.0 0.960028165261316 26 P30040,O95429,P17858,Q9UHD1,Q99653,P49257,P41240,Q99728,Q16850,P46060,Q6WKZ4,Q9Y385,P31689,Q00535 14 +Positive regulation of lamellipodium assembly 0.3367232399858757 0.2546293641924137 0.7990093772151978 1.0 0.9615168066691062 12 Q16625,P42345,P50570,Q7L576 4 +Regulation of fatty acid oxidation 0.4032695251999059 0.2543329059032843 0.7992383801572709 1.0 0.9615168066691062 5 P50416 1 +Response to retinoic acid 0.3365519989971431 0.2541071004222849 0.7994128180330409 1.0 0.9615168066691062 12 Q9NVR5 1 +Positive regulation of growth 0.2528483227166518 0.2535848847447731 0.7998162752372351 1.0 0.9618214866096728 44 Q96PU5,P16989,Q9BSK2,Q13868,Q9HBM6,Q96K76 6 +Cytokine mediated signaling pathway 0.2599457184889115 0.2500408606890484 0.8025557497441844 1.0 0.9638316051457716 35 Q6PD62,Q8N5M9,P67870,P63241,P33121,P18031,Q14166,Q15648,Q8WU90,O94813,P43034,P17252,Q99943,Q13418 14 +Postsynaptic modulation of chemical synaptic transmission 0.3555093868130418 0.2493754180622234 0.8030703981581051 1.0 0.9638316051457716 3 Q7L576 1 +Nuclear transcribed mrna poly a tail shortening 0.401073939186528 0.2489844612973675 0.8033728010774774 1.0 0.963926983274456 5 O95453,P11940,P62487 3 +Late endosome to lysosome transport 0.400710287505184 0.2481969866578475 0.8039819977235154 1.0 0.9644466528118542 6 Q9NVJ2,O95295,Q96QK1 3 +Positive regulation of microtubule polymerization or depolymerization 0.3030292510772748 0.2474426323754899 0.8045656838736759 1.0 0.9647854794126484 15 Q16625,P63000,P23396,Q14203,P36405,Q15691 6 +Regulation of peptidase activity 0.2443630038725084 0.2470864286216117 0.8048413365565397 1.0 0.9647854794126484 76 Q15392,Q13794,Q92688,O95831,Q9P0J0,Q96HY6,Q13547,P51812,O43847,Q96F07,Q9C0C9,Q9UL46,Q96K76,P61586 14 +Toxin transport 0.3220034254489295 0.2466740495592897 0.8051604914980768 1.0 0.9648069787760344 13 Q9C0I1 1 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.3569284523639769 0.2457324688757816 0.8058893361643018 1.0 0.9652844865885114 10 Q14103,P67809,O75534,Q9H2U1,P11940,O60506,A5YKK6 7 +Positive regulation of blood pressure 0.3994944352580958 0.2455641479465307 0.8060196452943096 1.0 0.9652844865885114 4 P61586 1 +Cellular response to peptide 0.2426217335789543 0.2451860098973222 0.8063124083258078 1.0 0.9652844865885114 64 Q8TBX8,Q9HCD5,Q9BSK2,Q13131,Q9UQB8,Q6IQ22,O60343,Q86YS7,Q7L576,Q00535,P62993,P31751,Q9UNS1,P43490,Q96A49,P11802,O14654,O60763,O43865,P41240,P61981,Q9BZF1 22 +Regulation of anoikis 0.3984400882880721 0.2430532188105306 0.807964170607367 1.0 0.9661522256395751 4 Q07820 1 +Localization within membrane 0.2294967965911057 0.2426922661028347 0.8082437991262073 1.0 0.9661522256395751 168 Q9HD20,P61619,Q9UHD1,Q9Y371,Q5BJH7,O43752,Q6IQ22,O14976,Q86YS7,P41440,Q13641,Q9P0I2,P31751,Q12955,P62072,Q9BZG1,Q9Y2J2,Q9BRK0,P98194,Q13277,Q07812,O00471,O95429,Q8N2H4,P09132,P55196,P63010,P46379,Q99653,Q15070,O60725,Q9P0J0,Q9NPA0 33 +Establishment of endothelial barrier 0.3324145086175752 0.2416982018084868 0.8090140230093612 1.0 0.9665607450549772 12 P62820,P35611 2 +Regulation of neurotransmitter levels 0.2669859194879627 0.2404745943664482 0.8099623562472698 1.0 0.9665607450549772 27 O00186,Q4J6C6,P56545,P80404,Q13277,O95295,P35080,P41440,P20339,O00161,Q00535 11 +Regulation of cell projection assembly 0.2526601822887088 0.2399296475846462 0.8103847965950151 1.0 0.9665607450549772 41 Q16625,P51114,P42345,P50570,Q8WXH0,Q15555,O94813,Q7L576,Q9NVG8 9 +Positive regulation of lamellipodium organization 0.3074819614146201 0.2399149977183826 0.8103961538698536 1.0 0.9665607450549772 14 Q16625,P42345,P50570,Q7L576 4 +Mast cell activation 0.3897944379740489 0.2392964324531618 0.8108757315535629 1.0 0.9668203595800532 7 P09601 1 +Positive regulation of lipid kinase activity 0.3968108519541149 0.2392046185442129 0.8109469215308309 1.0 0.9668203595800532 4 Q99570 1 +Regulation of cell morphogenesis involved in differentiation 0.2648826120114588 0.2390201938429772 0.8110899240907188 1.0 0.9668203595800532 28 Q9UQB8 1 +Response to toxic substance 0.2411444374358882 0.2386245258156717 0.8113967455848736 1.0 0.9668540833736422 54 P28161,P00374,P07196,Q07812,Q8TED1,P10620,Q96KQ7,Q15165,Q6DKJ4,O95831,Q9Y5Z9,P78417,P35670 13 +Regulation of protein polyubiquitination 0.389213775178706 0.237882003934566 0.8119726136934557 1.0 0.9669656878863666 7 P61088,O75150,O95071,Q96FW1,O00571,Q14669 6 +Keratinocyte migration 0.396117910299995 0.2375793498489279 0.8122073684143474 1.0 0.9669656878863666 4 Q15555 1 +Regulation of keratinocyte migration 0.396117910299995 0.2375793498489279 0.8122073684143474 1.0 0.9669656878863666 4 Q15555 1 +Negative regulation of smoothened signaling pathway 0.3510707332900662 0.2375306554835266 0.8122451399495065 1.0 0.9669656878863666 3 P17252,P63244 2 +Trna metabolic process 0.2442725556160579 0.2367210402411217 0.8128732110724526 1.0 0.9673538528943212 84 Q9P2J5,P26640,Q5VV42,Q9H974,Q9UKN8,Q99575,P62875,Q5KU26,Q7Z2T5,Q13868,P62312,Q9NNW5,Q9NQT5,Q15024,O75648,Q5JTZ9,Q08J23,Q96B26,Q5T160,Q9Y5Q9,Q5JPH6,O95363,Q9Y5Q8,Q9NSE4 24 +Neuron maturation 0.3953261927945516 0.2357309094164661 0.8136414834539745 1.0 0.967779776645783 4 P51608,O75503,O60341 3 +Cell projection assembly 0.2439763096469378 0.2355772320201363 0.8137607424782374 1.0 0.967779776645783 83 Q9Y5K6,Q9Y5K8,O95429,Q14141,Q16625,P51114,P50570,P42345,Q8WXH0,Q15555,P62820,Q9NVR5,O00471,O94813,Q96J42,A6NIH7,Q92538 17 +Mannosylation 0.3798733732935489 0.2350437327881467 0.8141747900006853 1.0 0.967779776645783 8 Q9BT22,O60762 2 +Regulation of gliogenesis 0.352807305051125 0.2344731426100731 0.8146176811812493 1.0 0.9678117332431536 10 Q96G23,Q13547,P42345 3 +Meiotic chromosome condensation 0.3941697941069184 0.2330473775969805 0.8157246164290848 1.0 0.9682802161543338 4 Q15021 1 +Selective autophagy 0.2690373021685376 0.2327008729138271 0.8159936913339667 1.0 0.9683402187432446 24 Q9Y3C8,A6NDU8,Q96HY6,Q9Y679,P12235,O15269 6 +Nls bearing protein import into nucleus 0.378862699961245 0.2325373985800632 0.816120643302338 1.0 0.9683402187432446 8 Q8NFH5,O00410 2 +Regulation of lyase activity 0.393643948887954 0.2314183046227101 0.816989846047304 1.0 0.968624404279812 6 P08754,Q9H1K1,Q13586 3 +Muscle adaptation 0.316854039852067 0.2310013312339473 0.8173137678232543 1.0 0.968624404279812 13 P09601,P50750 2 +Endosomal transport 0.2403724876482653 0.2309722403074741 0.8173363679953303 1.0 0.968624404279812 61 Q567U6,Q15907,P40616,P49257,Q14203,O60749,O95249,Q96QK1,O43752,Q96D71,Q9UBQ0,Q13492,P14373,Q9C0C9,Q9BRG1,P53367,Q92538 17 +Regulation of dna recombination 0.24288627181135 0.2308663974082365 0.8174185965558325 1.0 0.968624404279812 49 Q68CP9,Q9UBU8,Q9UNS1,Q86V81,Q9NQT5,Q96T76,Q9NRR5,P49959,P35637,Q96B01,Q9NY27,O14757,O96028 13 +Rrna base methylation 0.3931818181818222 0.2303394964855701 0.8178279718418953 1.0 0.968751107178103 5 O43709,Q92979,Q86W50,Q96P11 4 +Positive regulation of response to cytokine stimulus 0.3505691056910461 0.2285036435505139 0.8192547239017585 1.0 0.9696477811124452 10 P0DMV9,Q9NZI8,Q13546,Q7Z434,Q15648,P61086,P43034,Q99943,Q08211 9 +Regulation of organ growth 0.3630528892217414 0.2258121490605778 0.8213475275342155 1.0 0.9707829509176752 9 Q99956 1 +Positive regulation of catalytic activity 0.2260372199556549 0.2255989884767689 0.8215133276498154 1.0 0.9707829509176752 174 Q8NDZ4,Q96T88,Q15555,Q13432,Q9BRX5,Q96HY6,Q8WU90,Q96M27,Q99570,Q9UL46,Q9ULW0,Q14344,P31751,P00374,P23396,P18887,P61586,Q86U42,Q96A49,Q8IZ81,Q05639,P40616,P14635,Q92688,Q13586,Q07812,Q96N67,Q9NQS7,Q9BRT9,Q13492,Q96F07,Q16763,O95831,P40938,P42345,P33121,Q13794,Q9HAW4,Q9BZF1,Q8WTV0,P54619,P55196,P49959,Q9P0J0,Q9NVG8 45 +Positive regulation of protein kinase b signaling 0.2957758577902339 0.2239576462598614 0.8227902595234264 1.0 0.971959803515636 15 Q13641,O95429,Q9NQC3 3 +Postsynaptic membrane organization 0.3898209823249193 0.2231301673153596 0.8234342000316721 1.0 0.9721209247340404 4 P46109 1 +Positive regulation of gliogenesis 0.3829495251267274 0.2229672087639074 0.8235610276933933 1.0 0.9721209247340404 7 Q13547,O14744,P42345 3 +Regulation of cilium assembly 0.3140571385659087 0.2227785884410747 0.8237078331964363 1.0 0.9721209247340404 13 Q8WXH0,Q15555,P50570 3 +Positive regulation of behavior 0.3449059052563186 0.2216724886767256 0.8245688481610349 1.0 0.9725995288749016 3 Q92769,Q96QK1 2 +Positive regulation of protein polyubiquitination 0.3888347938980916 0.2209198105222818 0.8251548719303268 1.0 0.9729588625371312 4 P61088,O75150,O00571 3 +Establishment of protein localization 0.2220243676308929 0.220431878279267 0.8255348206417603 1.0 0.9729588625371312 497 Q8NFH4,Q9UHD1,Q7Z3U7,Q13432,Q03519,Q5BJH7,O00410,Q99570,Q8NC96,Q9BRG1,Q92538,Q9P0I2,Q9H7B4,P50570,O14653,A0AVF1,P62072,Q32P28,Q9UBV2,Q9UHQ4,Q9Y385,P60520,Q15907,Q9BRK0,P55786,P80404,Q8TB36,O60830,O95831,A6NIH7,O95373,Q03518,O43731,O95429,Q8N2H4,P61981,Q9UP83,P50416,O95249,Q96CW1,Q9P0J0,Q9Y5M8,Q9NVG8,Q567U6,P61619,P17858,P57105,P52292,P49257,O60749,Q9NRW7,Q9Y371,O43752,O95295,O95070,Q07820,Q99595,Q9UBQ0,Q9Y3B3,Q00535,O75381,O43592,Q96RT1,Q96RL7,Q12955,Q9UI26,Q9Y282,Q14746,P40616,P24390,Q9Y679,P83436,Q9Y3E0,P46379,Q15070,O60725,Q9NPA0,Q9HD20,Q96EE3,P51809,Q6NUQ1,O43823,O60831,Q6IQ22,Q86YS7,Q96ES7,O75396,Q96P70,Q9Y5K6,P61009,Q13555,Q99653,O96008,Q5JRA6,Q10713,Q9NP72,O15126,P31751,O95782,Q969Q5,Q9BZG1,Q9HCM4,Q12907,O94832,P98194,Q92688,Q13277,Q07812,O43865,O00471,Q96PC5,Q6WKZ4,Q8NFH5,Q92973,P20645,P09132,Q9HAS0,P62820,Q9P275,P63010,P55196,O96028,O94979 123 +T cell lineage commitment 0.3876038198386352 0.217717308655102 0.8276493768065654 1.0 0.9749764449839752 5 P61586 1 +Receptor clustering 0.3726057803718515 0.2174152531942503 0.8278847451594755 1.0 0.9750744029217872 8 P46109,Q00535,P57105 3 +Regulation of cation channel activity 0.2999175511483952 0.2166484148303019 0.828482352105333 1.0 0.9752403431802212 14 Q12955,P78417 2 +Regulation of sodium ion transmembrane transport 0.2997299285262418 0.2160922465562432 0.8289158432960493 1.0 0.9753921550614424 14 Q96PU5,P50570,Q9UHD1,Q12955,Q99653 5 +Maintenance of cell number 0.2568767599481401 0.2154867317843695 0.8293878555938106 1.0 0.9754163483901503 29 Q6PD62,Q9BXW9,P26196,Q6P2C8,Q5T200,O60244 6 +Protein export from nucleus 0.2627510221896419 0.2136767712910039 0.8307991268118085 1.0 0.9759561867834152 25 Q9UHD1,P50402,Q92688,P55060,Q9UIA9,O43865,P62826,P46060,P17252,O14980,Q99653,Q99728,Q00535,Q9HAV4 14 +Regulation of microvillus organization 0.341336794289419 0.2128111286133442 0.8314742831913731 1.0 0.9759561867834152 3 Q16658,Q14651 2 +Amino acid import 0.3705603121890263 0.2126198903439175 0.831623455912444 1.0 0.9759561867834152 8 P30825,Q15758 2 +Regulation of translational elongation 0.3844440786506443 0.2112533357525142 0.8326895938177477 1.0 0.9763508124619004 4 P49458 1 +Cytoskeleton organization 0.1967867812983787 0.2105529979534821 0.8332360921979278 1.0 0.9763509066434838 285 Q16625,Q9NUQ9,O75376,Q15555,Q9UQB8,O94813,Q96CW5,O94901,O75381,Q96RT1,P29966,Q12955,Q9Y2J2,P35611,P14373,Q08722,Q9HCM4,P61586,Q9H2J4,Q96DB5,O94832,Q9Y4F1,P98194,Q8WXH0,P14635,Q96N67,Q9H6D7,Q9NVR5,Q96P70,Q96F07,Q13576,Q4VCS5,Q8N3U4,P07197,P49006,Q9Y5K6,O95429,Q9UEY8,Q8IX90,Q9Y613,P07196,P52732,Q99653 43 +Establishment of protein localization to vacuole 0.3208838739076327 0.2092782261683925 0.8342310484316877 1.0 0.9769806391688102 12 Q99570,Q96RL7,P20645 3 +Negative regulation of lipid localization 0.3831891329867782 0.2085431012255416 0.8348049324218474 1.0 0.9772953942058396 4 P31751 1 +Regulation of t cell proliferation 0.2834480712727786 0.2071526537638181 0.835890642052247 1.0 0.9780003295465622 16 P30825,P23396,Q9HCL2,Q96J02 4 +Response to organic cyclic compound 0.2244822846050336 0.2065484070822567 0.8363625564410893 1.0 0.9780003295465622 158 Q86X55,Q96HY6,O94813,P41440,Q13126,Q9H7B4,P00374,Q9NUD5,P49721,P61586,P11802,Q05086,O95831,P30520,P33121,Q13794,P07196,P50416,O75874 19 +Regulation of brown fat cell differentiation 0.3387410772225773 0.2065153605740403 0.8363883673401507 1.0 0.9780003295465622 3 Q9C0B1,Q92766 2 +Torc1 signaling 0.3824499150877717 0.2063819322036113 0.8364925830524319 1.0 0.9780003295465622 6 P42345,Q96EE3 2 +Microtubule cytoskeleton organization 0.2221212036515371 0.20611825110248 0.8366985425461779 1.0 0.9780003295465622 139 Q16625,Q9UHD1,O75376,Q15555,Q14203,Q13131,Q96CW5,Q9ULW0,O94901,Q00535,O75381,P63000,P29372,P23396,P38398,A0AVF1,O75312,P36405,P61586,Q96DB5,Q03001,P14635,Q8WXH0,Q96N67,Q9NQS7,Q9H6D7,Q9NVR5,Q15691,Q96P70,O14757,Q8N3U4,Q8WWK9,Q8IX90,P07196,P52732,Q9Y6G9,Q68CZ6,P24941,Q99653 39 +Positive regulation of organelle organization 0.2235563044984279 0.2058050843493928 0.8369431694835134 1.0 0.9780003295465622 147 Q16625,Q8TBX8,Q9UJX2,P49257,Q15555,Q14203,Q9Y371,Q9UQB8,Q15047,Q96B01,Q9UN86,Q9NTJ3,Q86YS7,Q96A26,Q7L576,Q00535,Q9BPX3,P63000,Q9UJX3,P62993,P31751,P23396,P36405,P14373,Q08722,P61586,P60981,Q07812,Q9UJX4,Q15691,P12235,Q15021,Q8IY18,O95429,P42345,Q13794,Q9C0E8,Q9Y613,O95453,P24941,P49959,Q96QK1 42 +Crd mediated mrna stabilization 0.3674310817034574 0.2054262401998412 0.83723912070455 1.0 0.9780003295465622 8 Q14103,O75534,P11940,P67809 4 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.3674310817034574 0.2054262401998412 0.83723912070455 1.0 0.9780003295465622 8 Q14103,O75534,P11940,P67809 4 +Regulation of dna metabolic process 0.2202102781507084 0.2044923010944642 0.8379688077224918 1.0 0.9783175108930714 133 Q8NB78,Q03164,P52292,Q9BRX5,Q96KQ7,Q96B01,Q9NY27,O95071,Q9UNS1,Q86V81,P23396,P18887,P50750,Q9NRR5,Q68CP9,Q9NQT5,Q07812,Q9BRT9,O95831,O14757,P40938,Q9UBU8,Q96T76,P35637,P24941,P49959,Q96S55,O96028 28 +Smooth muscle contraction 0.3738801646167431 0.2025040282084471 0.8395227095927082 1.0 0.9792393440733592 7 P80404,P61586,P20020 3 +Nuclear pore organization 0.3180933165672883 0.2019178319874377 0.8399809612875235 1.0 0.9793413007284028 12 Q9NQC3,Q96EE3 2 +Positive regulation of membrane potential 0.38018851530912 0.2015574259525546 0.8402627312148068 1.0 0.9793413007284028 6 Q12955,P31751 2 +Purine containing compound metabolic process 0.2204886775148624 0.201269738546984 0.840487663504413 1.0 0.9793413007284028 136 Q9NZ01,P85037,O75376,P00846,Q02218,Q13126,Q9BRR6,O75414,Q9UKU0,Q53GQ0,P61586,Q9P2R7,Q9NVE7,Q8TB61,A8MXV4,Q9UJZ1,Q9BW91,P30520,P49902,O75964,P33121,O60725,O43252,P56134,O60313 25 +Positive regulation of chromosome segregation 0.3732898380764643 0.2012189280568792 0.8405273917272493 1.0 0.9793413007284028 7 P14635,Q96SB8 2 +Establishment of protein localization to plasma membrane 0.2669541238583558 0.1999334943318963 0.8415325945789136 1.0 0.9793542470518212 21 Q8N2H4,Q12955,P98194,Q9BZG1 4 +Regulation of dna helicase activity 0.3357832965817307 0.1994952972142165 0.8418753217013872 1.0 0.9793542470518212 3 P49736 1 +Positive regulation of transcription of nucleolar large rrna by rna polymerase i 0.3723097142681524 0.1990979884692973 0.8421860947002784 1.0 0.9793542470518212 7 Q12824 1 +Blood vessel morphogenesis 0.2352423486637286 0.1990483432950333 0.8422249286468304 1.0 0.9793542470518212 74 Q68CP9,Q9H2J4,Q14344,Q96AY3,Q9NZ08,Q5JRA6,Q9H6E4,Q13586,P78362,P61586,O94813,Q9BXJ9,Q4VCS5,P09601,P42785 15 +Supramolecular fiber organization 0.2228588007341414 0.1984345997065731 0.8427050489857613 1.0 0.9793542470518212 153 Q16625,Q9NUQ9,Q9UHD1,O60925,Q9UQB8,O94813,Q96CW5,Q6WCQ1,Q96AY3,P29372,P29966,P23396,P35611,P13674,P14373,Q08722,P61586,O15145,O94832,Q07812,Q96P70,Q96F07,Q13576,P07197,P49006,Q9Y5K6,O95429,Q9UEY8,P42345,Q9Y613,P07196,Q99653 32 +Negative regulation of response to dna damage stimulus 0.2593647617368745 0.1980507381748422 0.8430053665483235 1.0 0.9793542470518212 24 O95071,Q9HBM6,P18887,P23396,Q9NRR5,Q96K76 6 +Regulation of type i interferon mediated signaling pathway 0.3514304291287438 0.1978314628881788 0.8431769288134969 1.0 0.9793542470518212 9 Q9NZI8,P18031,Q14166,Q7Z434,P61086,Q9Y3Z3,P08238,Q16543 8 +Negative regulation of secretion 0.2868101714337321 0.1971560568804102 0.8437054171518614 1.0 0.9796586736042822 15 P30040,O00186,Q8N5M9,P17858,P80404,Q16850,Q6WKZ4,P09601 8 +Positive regulation of rna splicing 0.2615889825643438 0.1968855683790761 0.8439170874004553 1.0 0.97972686877262 23 P98179,Q15427 2 +Positive regulation of neural precursor cell proliferation 0.3777952524658666 0.1965378347396196 0.8441892222404106 1.0 0.9798652215386972 6 P07948,P55209,O60341 3 +Polyol metabolic process 0.2672952226364203 0.194997044714366 0.8453952611912099 1.0 0.9804074142108576 20 P00374,P61457,Q10713,Q13614,O15269 5 +Microtubule polymerization or depolymerization 0.2473317821111766 0.194061675501483 0.84612758963552 1.0 0.9804669685077988 34 Q16625,Q8WWK9,Q8IX90,P63000,P29372,P23396,Q15555,Q14203,Q15691,Q96P70,Q96CW5,Q9ULW0 12 +Regulation of behavior 0.3764883574096694 0.1939634713018523 0.8462044843535697 1.0 0.9804669685077988 5 P42345 1 +Organophosphate biosynthetic process 0.2221177856046356 0.1935713450798122 0.8465115370922027 1.0 0.9804669685077988 156 Q96BW9,Q9NZ01,Q8TBX8,Q9UHD1,Q9NPH0,Q8WWI5,Q10713,O60762,Q13614,Q99570,P00846,O75414,Q8WVC6,P43490,Q53GQ0,Q9UKU0,Q9HCL2,Q8NFF5,O15269,Q9NVE7,Q8TB61,Q9UG56,Q9UJZ1,P30520,O15228,O75964,P33121,O75874,P17812,Q14558,O43252,P14324,P56134,Q99653,Q7L5N7 35 +Negative regulation of nucleocytoplasmic transport 0.3620813970424409 0.1935295030920766 0.846544302656359 1.0 0.9804669685077988 8 Q99653,Q00535,Q99728,Q9UHD1 4 +Negative regulation of striated muscle cell differentiation 0.374676194847591 0.1907813039944337 0.8486969368925514 1.0 0.9822497882084344 4 Q13547 1 +Membrane disassembly 0.3682059048582742 0.1903904394702815 0.8490031888545517 1.0 0.9823758862871528 7 P17252,Q14203,P43034 3 +Intracellular transport 0.2161706613080011 0.190250813434316 0.8491125948129823 1.0 0.9823758862871528 516 Q9UHD1,O43772,Q7Z3U7,Q03519,Q5BJH7,O00410,A4D1P6,P00846,Q99570,Q9BRG1,Q92538,Q8WU17,Q86V81,O14653,A0AVF1,P62072,Q9UBV2,Q9UHQ4,P14373,Q9Y385,Q15907,Q9BRK0,P55786,Q8TB36,Q9P260,O60830,Q13492,O95831,P12235,Q08J23,O95373,O43731,Q03518,O95429,Q8N2H4,P61981,O75964,Q8IXI1,P50416,O95249,Q96CW1,P54619,P56134,Q9P0J0,Q9BUP3,Q9Y5M8,Q9NVG8,Q567U6,P61619,P57105,P52292,P49257,P42765,O60749,Q9NRW7,Q9Y371,O43752,O95295,O95070,Q13614,Q99595,Q9UBQ0,Q9Y3B3,Q00535,O75381,O43592,Q96RT1,O95071,P61221,Q96RL7,Q12955,Q9UI26,Q86U42,Q6P6C2,Q9Y282,P40616,Q96N67,P24390,P62841,Q9Y679,P83436,Q13794,P07196,O15514,P46379,Q15070,O60725,O75152,P51809,Q6NUQ1,Q6IQ22,Q9C0C9,Q86YS7,O94901,O75396,Q8WXH0,Q96P70,Q9Y613,P61009,Q96D71,Q9Y5P4,Q99653,O60313,O96008,Q5JRA6,Q9UH62,Q10713,O14976,Q9NP72,P31751,O95782,Q969Q5,Q12907,O94832,Q92688,Q13277,Q07812,O43865,Q96PC5,Q8NFH5,Q92973,Q9UJZ1,P20645,P09132,Q9HAS0,P62820,Q9P275,P63010,O94979 129 +Positive regulation of cell cycle phase transition 0.2411043092620718 0.1886917977007394 0.8503343805947201 1.0 0.9828223018434086 40 Q9UJX2,Q9UJX3,P31350,P54652,P14635,Q96FV9,Q96HY6,Q9UJX4,Q96FF9,Q96DY7,P11802 11 +Positive regulation of transcription by rna polymerase ii 0.2211013705785985 0.187928778145173 0.8509324829503009 1.0 0.9828223018434086 159 Q8NB78,Q96T88,Q03164,Q9UH62,Q96HY6,Q13547,Q8IZL8,Q9H7B4,Q9BZK7,Q9Y2X0,P43490,P50750,Q05086,O60244,Q71SY5,Q9Y613,P35269,Q8WUB8,Q12824 19 +Phosphatidylinositol metabolic process 0.2587014365919532 0.1875024049809277 0.8512667382273624 1.0 0.9828223018434086 23 Q8TBX8,Q9C0I1,Q10713,O60762,Q13614 5 +Transcription by rna polymerase iii 0.2610029339367808 0.1874851320033819 0.8512802799431516 1.0 0.9828223018434086 22 P42345,P55199,P62875,Q9Y5Q9,O15160,Q9Y5Q8,Q9HCK8,Q659A1,Q9UKN8 9 +Dna templated transcription elongation 0.239628368104594 0.1872886986760577 0.8514342833601345 1.0 0.9828223018434086 42 Q6PD62,Q86V81,P55199,P35269,Q8IXH7,Q8WX92,O15160,P50750 8 +Actin filament based movement 0.2608233152682527 0.186918843030131 0.8517242649723129 1.0 0.9829122034611129 22 Q9UM22,Q8WXH0,Q9HCM4,Q96PU5 4 +Actin filament based process 0.2201751988543755 0.1862873938675192 0.8522193926704675 1.0 0.9829523639623722 149 Q9NUQ9,Q9UQB8,O94813,P29966,Q9Y2J2,P35611,P14373,Q08722,Q9HCM4,P61586,Q9H2J4,O94832,Q9Y4F1,Q8WXH0,Q96F07,Q13576,Q4VCS5,P49006,Q96PU5,O95429,Q9UEY8,Q9Y5K6,Q9Y613,Q9UM22 24 +Regulation of dna templated transcription initiation 0.2888168357165425 0.1855070870051766 0.8528313221133375 1.0 0.9830096057712502 14 Q9NYF8,P11802,O60244,Q9Y2X0 4 +Negative regulation of mitotic cell cycle 0.2338986784367486 0.1851975850958973 0.8530740631446458 1.0 0.9830096057712502 48 Q6NUQ1,Q9Y619,Q5JVF3,Q9BXW9,O75414,P38398,Q13564,Q7Z7L1,Q96K76,P14635,O60566,O43684,O14757,Q9HAW4,Q9Y6G9,P49959,O43264,P50748,P24941,Q96DY7,P43246 21 +Mitotic cell cycle 0.203042127077632 0.1846358550925801 0.853514661125343 1.0 0.9830096057712502 264 Q14166,Q13432,P25205,Q92538,Q14141,P50570,Q96IY1,Q96K76,Q9NQS7,Q9UJX4,O14757,P42771,Q9HAW4,P50748,P24941,P49736,Q96KB5,Q9NTJ3,O75935,Q9ULW0,Q00535,Q9UJX3,P31350,Q9H1A4,P38398,Q12955,P50750,Q96DB5,P49427,P14635,Q8N3U4,Q8IY18,Q8WWK9,Q9NY61,Q9H6H4,Q9Y6G9,Q96DY7,P49321,P43246,Q9UJX2,Q96EE3,Q6NUQ1,Q14203,O43823,Q5JVF3,Q03188,Q9BPX3,Q9BXW9,O75414,O43660,O75312,P33993,P36405,Q13564,Q15813,P61586,P11802,P53041,O60566,O14744,O43684,Q16763,Q15021,Q8IX90,Q13616,P54652,P52732,Q53HL2,O43264,O60216,P17252,Q9Y619,Q9BRX5,Q9P287,P83731,Q13561,Q96CW5,Q9UL46,P06730,P43034,P61254,Q9BUF5,O75717,Q7Z7L1,O00571,P08243,P63096,P78527,Q9Y2Z0,Q6DKK2,Q96FF9,P49959 92 +Regulation of dna strand elongation 0.3717532467532536 0.1844175224803016 0.8536859246140855 1.0 0.9830096057712502 5 Q9H1E3,Q9Y5K5,Q9Y230,O96019 4 +Regulation of tube size 0.3577685246242357 0.1843093424284284 0.8537707852807015 1.0 0.9830096057712502 8 Q9HB40 1 +Regulation of hematopoietic progenitor cell differentiation 0.3652380178607447 0.1842675935300066 0.8538035352031277 1.0 0.9830096057712502 7 O43809,P19525,Q96J02 3 +Hypothalamus development 0.3711001381074855 0.1831279275407621 0.8546976432878635 1.0 0.9835087305374624 5 Q07812 1 +Regulation of intracellular signal transduction 0.2087035500905713 0.1827589904266333 0.8549871274808336 1.0 0.983528804812169 249 Q8NDZ4,Q9NUQ9,Q9UHD1,Q96EE3,Q99956,O75376,Q15555,Q01085,Q13547,Q10713,O94813,P41440,Q9NWT1,Q92538,Q13418,Q13641,O43657,Q14344,P78318,Q96RT1,P50570,P29372,Q9NUD5,P16989,Q9UMX5,P14373,Q9HBM6,P09601,Q96K76,P61586,Q05086,P98194,Q8TB61,P14635,Q07812,Q96J02,Q9NQC3,Q96P70,P62841,Q4VCS5,Q9Y5K6,O95429,P42345,Q13794,Q9Y3E0,Q99653,O60313,Q9P0J0 48 +Inner ear receptor cell stereocilium organization 0.3705259490598674 0.1825186931484486 0.8551756857327164 1.0 0.983528804812169 4 O95487 1 +Mitochondrial fusion 0.2873426598235701 0.1816429371150839 0.8558629503913766 1.0 0.9836825414072072 14 Q9NX63,O60313,Q07812,Q9UJZ1 4 +Amyloid beta formation 0.3440297721191104 0.1813700298008585 0.8560771414837933 1.0 0.9836825414072072 9 Q16799 1 +Odontogenesis of dentin containing tooth 0.3431335888234899 0.1794487754709651 0.8575853356094381 1.0 0.9848855611176156 9 Q13547,Q13586 2 +Maintenance of cell polarity 0.3687114573190568 0.1789884466113029 0.8579467734687012 1.0 0.9851240420936548 4 O00151,Q03001,Q8WUM4 3 +Cellular response to oxygen containing compound 0.2147117151993408 0.176423581576495 0.859961179800182 1.0 0.9861996630504772 187 Q99720,Q8TBX8,Q9P2J5,Q9HCD5,Q96RR1,O43823,Q96QK1,Q9BSK2,Q13131,O00410,Q9UQB8,Q96KQ7,Q6IQ22,O60343,O94813,Q86YS7,Q7L576,Q00535,Q6PD62,Q9H7B4,P17480,P62993,P50570,P00374,O15164,P23396,P38398,Q9UNS1,Q15648,O95563,Q5KU26,P20020,P43490,P61586,Q86U42,Q15907,O14654,P11802,Q96A49,O60763,Q9Y2Q5,Q99729,P08754,Q8TB36,O14744,P31751,Q96C86,O43865,P41240,O95831,P61981,P42345,Q9BZF1,P50416,Q8WTV0,P10620,P24941,Q9P0J0,Q12824 59 +Positive regulation of myeloid leukocyte differentiation 0.3247890979883123 0.1748527547948254 0.8611953344701133 1.0 0.9866475637119162 3 Q13546,P17252 2 +Regulation of gene silencing by rna 0.2784550295994784 0.1744287529047031 0.861528519125409 1.0 0.9866475637119162 15 O75376,P51114,Q01085 3 +Cellular response to prostaglandin e stimulus 0.3660789578821578 0.1739558119938898 0.8619001895919642 1.0 0.9866475637119162 4 O43823 1 +Response to prostaglandin 0.3660789578821578 0.1739558119938898 0.8619001895919642 1.0 0.9866475637119162 4 O43823 1 +Cellular response to prostaglandin stimulus 0.3660789578821578 0.1739558119938898 0.8619001895919642 1.0 0.9866475637119162 4 O43823 1 +Response to prostaglandin e 0.3660789578821578 0.1739558119938898 0.8619001895919642 1.0 0.9866475637119162 4 O43823 1 +C4 dicarboxylate transport 0.3273688378485803 0.1727868037439371 0.8628190101134403 1.0 0.9868270985157468 10 Q15758 1 +Regulation of translational fidelity 0.2944636154384996 0.171009409407656 0.86421636694668 1.0 0.9877866613111528 13 P26640,Q5JTZ9,Q9NSE4 3 +Rna capping 0.3641659394697895 0.1703649228797407 0.8647231563276925 1.0 0.987946591659568 4 Q8N1G2,Q53F19 2 +Mitochondrial fragmentation involved in apoptotic process 0.3639784146103577 0.1693055894126168 0.8655562797352785 1.0 0.9880483129229082 6 Q07812,Q96QK1 2 +Regulation of cell morphogenesis 0.2276935795439028 0.1688586596076305 0.8659078170286167 1.0 0.9880483129229082 61 O15031,Q9UQB8,Q96PU5,Q13418 4 +Positive regulation of cell differentiation 0.2273740455265511 0.1687346540378525 0.8660053596059438 1.0 0.9880483129229082 104 O15031,Q8WUJ1,P07196,Q86X55,Q9UQB8,P35611,Q16706,Q13547,P51812,O94813,P61586,P55209,Q13418 13 +Positive regulation of leukocyte migration 0.2934698301405057 0.1686582116869826 0.8660654900504374 1.0 0.9880483129229082 13 P61586,Q08722 2 +Response to insulin 0.2268479935676009 0.1684354395616518 0.8662407296220969 1.0 0.9880483129229082 56 Q8TBX8,Q9HCD5,Q9BSK2,Q13131,Q9UQB8,Q6IQ22,O60343,Q86YS7,Q7L576,P62993,P31751,P20020,P43490,Q96A49,P11802,O14654,O60763,P61981,P42345,Q9BZF1 20 +Negative regulation of actin filament polymerization 0.2617067268701367 0.1681293479491661 0.8664815216499324 1.0 0.9880483129229082 18 Q9UEY8,P35611,O94813 3 +Collagen fibril organization 0.349185340651063 0.1669501635633677 0.8674092621741472 1.0 0.9880483129229082 8 Q96AY3 1 +Cell cycle g1 s phase transition 0.2282721313170197 0.1666578352969201 0.8676392840065186 1.0 0.9880483129229082 49 P61254,P42771,P49427,P31350,Q13616,O43660,O75312,Q96HY6,O00213,O00571,Q7Z7L1,Q9UL46,Q96DY7,P24941,P06730,P49321,P11802,Q00535 18 +Modulation by host of symbiont process 0.2560627454047973 0.1665484586287701 0.8677253511679888 1.0 0.9880483129229082 21 Q12824,P50750 2 +Multicellular organism reproduction 0.2249774822781549 0.1649896850123311 0.868952100958341 1.0 0.9880483129229082 107 Q8NB78,Q01085,Q96KQ7,O94813,Q8IZL8,O94901,Q9BXW9,Q14141,P50570,P25440,Q96SI9,A0AVF1,P16989,P14373,Q6P6C2,Q07812,Q99417,P42345,P54652,P24468,P46379 21 +Ion homeostasis 0.2254143668122297 0.1645634610003839 0.8692875929338721 1.0 0.9880511569081591 106 Q9HD20,Q9Y487,Q8NE01,Q14344,Q9UM00,Q12955,Q9HC07,P09601,Q93050,P78417,Q05086,P30519,P98194,Q13586,Q07812,Q9UJZ1,Q96PU5,O43819,Q99653 19 +Cellular ion homeostasis 0.2297908407999276 0.1628106817861069 0.8706674976420656 1.0 0.9884338941982026 91 Q96PU5,Q14344,Q9HD20,Q93050,P98194,P28161,Q9UM00,O43819,Q13586,Q07812,Q9HC07,Q9Y487,Q99653,P09601,Q9UJZ1,P78417,Q05086 17 +Insulin metabolic process 0.318624269954566 0.1620441517337568 0.8712710852494108 1.0 0.9884338941982026 3 Q96HE7,Q8TAD4 2 +Monocyte differentiation 0.3598922537027182 0.1620243929247978 0.8712866448913954 1.0 0.9884338941982026 5 P35579,Q15648 2 +Microtubule organizing center organization 0.2390022124716027 0.1610345577671425 0.8720661826631715 1.0 0.9884338941982026 32 Q9UHD1,P52732,P38398,Q14203,Q68CZ6,Q9H6D7,P24941,P36404,O14757,P43034 10 +Positive regulation of nuclear division 0.3009541776392097 0.1609243244761764 0.8721530038260235 1.0 0.9884338941982026 12 Q9UJX4,Q9UJX3,Q96B01 3 +Poly a plus mrna export from nucleus 0.3212033026042677 0.1598939960757341 0.872964578109056 1.0 0.9884338941982026 10 Q86U42 1 +Negative regulation of protein serine threonine kinase activity 0.2596157532374611 0.1596540254929846 0.873153618579545 1.0 0.9884338941982026 17 P42771,O95373,Q9UHD1,P53350,P07948,P18031,P10644,O00410,P24468,P31689 10 +Central nervous system neuron differentiation 0.289543799646052 0.1596291912732908 0.873173182526948 1.0 0.9884338941982026 13 O94813 1 +Superoxide anion generation 0.357873143507093 0.1589470968805924 0.8737105543839614 1.0 0.988454878506622 4 P08754,Q9NY61 2 +Regulation of cellular component size 0.2275031293451104 0.1587875049617075 0.8738362935042743 1.0 0.988454878506622 76 Q9NUQ9,Q9UQB8,O94813,Q7L576,Q00535,Q9P265,P63000,P50570,O96011,Q9NUT2,P35611,P61586,O15145,P60981,Q9NQC3,Q8N0X7,Q13492,Q96F07,O95429,Q9UEY8,P42345,Q9UHB6,P07196,Q96CW1 24 +Neuroepithelial cell differentiation 0.3169532970544069 0.1586978677014182 0.8739069182162882 1.0 0.988454878506622 3 Q9P287 1 +Skeletal system development 0.2316377684437859 0.1585970832190541 0.8739863269640251 1.0 0.988454878506622 42 Q96HY6,O43252,Q32P28,Q9C0E8 4 +Negative regulation of histone methylation 0.3328032820711064 0.1584305677412201 0.87411752837028 1.0 0.988454878506622 9 P38398,Q7KZ85,Q12824,Q6W2J9 4 +Regulation of vesicle mediated transport 0.2238206256058281 0.1579576709478054 0.8744901535810061 1.0 0.988691128158548 106 P57105,P51809,Q6NUQ1,Q13432,O95295,Q6IQ22,Q13614,Q86YS7,P41440,Q00535,Q8WU17,P50570,P31751,Q08722,P09601,Q15907,Q12907,P98194,Q13492,Q9Y5K6,Q96PU5,Q96CW1,Q8WTV0,P63010 24 +Receptor catabolic process 0.3319886369441502 0.1568613554465576 0.8753541166410219 1.0 0.988691128158548 9 Q13614,Q99570,Q9Y371,Q96J02 4 +Regulation of homotypic cell cell adhesion 0.3570222539922214 0.1567286317053852 0.8754587210964437 1.0 0.988691128158548 6 P17252,P80404,Q12955 3 +Cell substrate adhesion 0.2296978992854164 0.1565205278195811 0.8756227397925707 1.0 0.988691128158548 44 P42771,P46939,P50570,P62820,Q9UM22,Q53GQ0,Q9HCM4,P61586,Q00535,Q13418 10 +Homologous recombination 0.3093169017923945 0.1564144808551619 0.8757063235877296 1.0 0.988691128158548 11 Q9BXW9,P49959,Q96B01,Q92878 4 +Regulation of cell cycle g2 m phase transition 0.233679671241482 0.1563288692711412 0.87577380169429 1.0 0.988691128158548 36 Q6NUQ1,P54652,P14635,Q9HAW4,Q9Y619,P24941,P49959,O14757,Q96K76,P11802 10 +Positive regulation of microtubule nucleation 0.3564935064935184 0.1560090803555702 0.8760258637747356 1.0 0.988691128158548 5 P51608,Q14203,Q14008,Q16512 4 +Regulation of microtubule nucleation 0.3564935064935184 0.1560090803555702 0.8760258637747356 1.0 0.988691128158548 5 P51608,Q14203,Q14008,Q16512 4 +Response to nitrogen compound 0.2101377984983224 0.1554599370128504 0.8764587355364335 1.0 0.9888331560138064 220 Q8TBX8,Q9HCD5,Q5JRA6,Q86X55,Q9BSK2,O00410,Q9UQB8,Q96KQ7,Q6IQ22,Q9NYU2,O94813,Q86YS7,P41440,Q8WU17,Q96RT1,Q9UNS1,P50570,P00374,P31751,P21953,Q9NUD5,Q9UBV2,P43490,P08574,P49721,Q9Y385,P61586,P11802,Q05086,Q96A49,Q92575,Q99729,P80404,O43865,O95831,Q9Y679,O14757,P30520,P61981,Q8IXB1,P42345,Q13794,P07196,P28161,Q9BZF1,P50416,P46379 47 +Immune response 0.2101033773816059 0.1546130467699424 0.8771263838539991 1.0 0.9888449068264108 188 Q9NUQ9,P51809,Q14166,Q03519,O43823,Q9Y487,Q9UQ84,P41440,O43657,Q92538,Q96RT1,Q9NUD5,Q9NPR9,P78362,P51812,P14373,Q08722,P09601,Q9Y5A7,Q9NZ08,Q9NQT5,Q07812,Q96J02,Q9NQC3,O14802,Q9UJZ1,Q03518,Q9Y5P4,P42345,O95801,O00178,P28070,P46379,O96028 34 +Multi organism reproductive process 0.21086992416006 0.1543749965571602 0.877314067173764 1.0 0.9888449068264108 138 Q8NB78,Q01085,Q96KQ7,Q96CW5,Q8IZL8,P41440,O94901,Q9BXW9,Q14141,P50570,P25440,Q96SI9,A0AVF1,P16989,P14373,Q9Y385,Q05086,P46926,Q6P6C2,P80404,Q07812,Q99417,P42345,P54652,P24468,P46379 26 +B cell activation 0.2316065129167732 0.154160727508538 0.8774830068694146 1.0 0.9888449068264108 38 Q9UQ84 1 +Positive regulation of protein autophosphorylation 0.3550988075740826 0.1541054242733205 0.8775266114216744 1.0 0.9888449068264108 4 P49959,Q92878 2 +Negative regulation of organic acid transport 0.354810170587496 0.1536084566394268 0.8779184686497168 1.0 0.9888449068264108 4 P31751 1 +Extrinsic apoptotic signaling pathway 0.234893021115267 0.1535953356547242 0.8779288149056672 1.0 0.9888449068264108 34 P09601,Q9P0J0,Q13794,P30154 4 +Regulation of immune system process 0.213398276381878 0.1534538537898892 0.8780403785569015 1.0 0.9888449068264108 164 Q9NUQ9,Q5JRA6,P51809,Q14166,O96005,O94813,P41440,O43657,P30825,Q9BXW9,Q6PD62,Q96RT1,P23396,Q9NUD5,Q9NPR9,P51812,P14373,Q08722,P09601,Q9HCL2,P61586,P04439,Q9NQT5,Q9NZ08,Q07812,Q96J02,Q9NQC3,Q9UJZ1,P42345,P28070,P46379,O96028 32 +Amyloid beta metabolic process 0.3076883175936064 0.153097358960408 0.8783214985704462 1.0 0.9888449068264108 11 Q16799 1 +Positive regulation of mitotic cell cycle 0.2306404065227163 0.1525539250709908 0.8787500620443214 1.0 0.989153557802833 40 Q9UJX2,Q9UJX3,P31350,P54652,O43660,P14635,Q9UJX4,Q96FF9,O00571,Q96DY7,P06730,P11802,P17252,P43034 14 +Negative regulation of protein export from nucleus 0.3537788001501422 0.1518430618537365 0.8793107174499524 1.0 0.9895579854025884 4 Q99728,Q00535 2 +Developmental cell growth 0.2316591978778837 0.1503172625143696 0.8805143142108154 1.0 0.9895579854025884 36 Q96PU5,Q9P265,Q96F07,O94813 4 +Response to gamma radiation 0.262247733022971 0.1499612192379706 0.8807952117666138 1.0 0.9895579854025884 16 P61254,P78527,Q9BXW9,Q07812,Q13131,O75844,O60341 7 +Mitotic spindle assembly 0.236223772627615 0.1497126469342952 0.8809913298325815 1.0 0.9895579854025884 29 Q8N3U4,P61586 2 +Organic cyclic compound catabolic process 0.2124634146556765 0.1496405705617655 0.8810481978665423 1.0 0.9895579854025884 162 Q9Y4Y9,Q92804,P60228,Q8IYS1,Q14011,Q9BQ61,Q7L8L6,Q969T7,Q13126,P62487,Q99575,P16989,Q13868,Q92945,P62312,Q9NRN7,P09601,P30519,Q6PGP7,Q6P6C2,P26572,P67809,Q9NQT5,Q99729,Q07812,A8MXV4,P98175,O95831,Q08J23,Q9BW91,P51114,Q96B26,P49902,Q9HCE1,O00178,Q8WTV0,O15514,Q9H773,P35637,Q9GZR2 40 +Negative regulation of cell cycle g1 s phase transition 0.3276801226493902 0.1487760836432257 0.8817303230726474 1.0 0.9895579854025884 9 P61254,P78527,P24941,Q7Z7L1,O00213 5 +Regulation of transferase activity 0.2111770725669235 0.1486380465621354 0.8818392496555119 1.0 0.9895579854025884 147 Q8NDZ4,Q8TBX8,Q9UHD1,P49736,Q13432,Q9BRX5,O00410,A4D1P6,Q96M27,Q99570,Q9BRG1,Q9ULW0,Q9H7B4,P23396,P14373,P61586,Q86U42,Q96A49,Q05639,P14635,O60566,Q9NQS7,Q9BRT9,P62841,Q16763,O95373,P40938,P42771,P61981,P42345,P33121,Q9HAW4,Q9BZF1,P49959,P54619,P24468,Q99653,O95816 38 +Lamellipodium morphogenesis 0.3519149793456217 0.1481883340644258 0.882194138237334 1.0 0.9895579854025884 5 O60749 1 +Negative regulation of intracellular transport 0.2522859152445972 0.1472238397593303 0.882955344218697 1.0 0.9898422195226678 19 O95429,Q9UHD1,Q99653,P49257,Q96QK1,Q9Y385,P53367,Q99728,Q00535 9 +Cellular response to osmotic stress 0.2943741188506616 0.1471142313211678 0.8830418571282717 1.0 0.9898422195226678 12 P16989 1 +Regulation of response to osmotic stress 0.3510232319390972 0.146492196850232 0.8835328494798611 1.0 0.9898422195226678 6 P16989 1 +Posttranscriptional regulation of gene expression 0.2088725224511315 0.1462951897721527 0.8836883630112609 1.0 0.9898422195226678 205 O15031,Q92804,P60228,Q14011,O75376,Q01085,Q71RC2,Q10713,Q7L8L6,Q5JVF3,Q96MU7,Q8TEQ6,Q9NP64,Q7L576,Q969T7,P05198,O15372,Q8WU17,P62487,P31751,P00374,P23396,P61221,P16989,Q5KU26,Q13868,Q92945,P51812,Q9HCM4,P61586,P98179,P42694,P26196,Q6P6C2,P67809,Q9NQT5,Q15024,P55010,Q13217,O15371,Q96C86,Q9Y6M1,Q15631,P98175,P23588,Q08J23,Q9Y6E2,Q96P11,Q96B26,P51114,P42345,Q9HCE1,Q567V2,O15514,O95453,P35637,P19525,P49458,P62263 59 +Mesoderm morphogenesis 0.3376347883596074 0.1456719652526549 0.8841803537375732 1.0 0.9901945116348186 8 Q16881,P17252,Q9HCM4 3 +Mitotic cell cycle checkpoint signaling 0.2287410785470755 0.1455051877016755 0.8843120201471741 1.0 0.9901945116348186 37 Q6NUQ1,Q9Y619,Q5JVF3,P61254,Q9BXW9,P38398,Q13564,P78527,P14635,O60566,O43684,O14757,Q9HAW4,Q9Y6G9,O43264,P50748,P24941,P49959,P43246 19 +Positive regulation of mitotic cell cycle spindle assembly checkpoint 0.309762757813701 0.144908814736015 0.8847828667462116 1.0 0.9902557366824288 3 Q9Y6G9 1 +Negative regulation of fibroblast proliferation 0.343192002616769 0.1433936811257236 0.885979273136754 1.0 0.9902557366824288 7 Q07812,Q71SY5 2 +Multivesicular body sorting pathway 0.3487012987013055 0.1428923071165786 0.8863752342575102 1.0 0.9902557366824288 5 P55072,Q96FZ7,Q9BRG1,O43633 4 +Endosome transport via multivesicular body sorting pathway 0.3487012987013055 0.1428923071165786 0.8863752342575102 1.0 0.9902557366824288 5 P55072,Q96FZ7,Q9BRG1,O43633 4 +Mitotic intra s dna damage checkpoint signaling 0.3483950322349078 0.1428909940021352 0.8863762713295422 1.0 0.9902557366824288 4 Q9BXW9,P49959 2 +Negative regulation of gliogenesis 0.3075924724205013 0.1409413164050658 0.8879163021333165 1.0 0.9911120110587256 3 Q96G23,P35222 2 +Protein localization to plasma membrane 0.2206023362219897 0.1404798461623594 0.8882808750135269 1.0 0.991346216957605 68 Q13641,O95429,Q8N2H4,P31751,P98194,Q12955,Q13277,Q9BZG1,Q9Y2J2,Q6IQ22,O00471,O14976,Q13492,P55196,Q86YS7,P41440 16 +Metal ion transport 0.2219791294049854 0.139429856842194 0.8891104804366419 1.0 0.991506363105932 99 Q9HD20,P61619,Q9UHD1,P50570,Q9NUT2,Q9UM00,Q12955,Q9HC07,P14373,P61586,P78417,Q15907,P46939,P98194,Q13586,Q07812,O43865,Q9UJZ1,P35670,Q96PU5,P28161,P54652,Q13555,Q99653 24 +Transferrin transport 0.346087648908046 0.1391893148495339 0.8893005518278136 1.0 0.991506363105932 4 Q15907,P50570 2 +Negative regulation of hormone secretion 0.3460501823567902 0.1384331218324475 0.889898121572211 1.0 0.991506363105932 6 Q6WKZ4 1 +Protein dna complex disassembly 0.2684679684989953 0.1377953404946968 0.8904021669776176 1.0 0.991506363105932 14 Q12824 1 +Regulation of organelle assembly 0.2169496554182565 0.1374930329561256 0.8906410993428944 1.0 0.991506363105932 52 Q8TBX8,P50570,Q8WXH0,Q15555,Q9Y371,Q96KQ7,Q9UN86,O75396,P61586,Q9NVG8 10 +Negative regulation of cellular catabolic process 0.2234673398526294 0.1374681773667187 0.8906607446962915 1.0 0.991506363105932 90 Q92804,P85037,Q14011,Q96KQ7,Q96HY6,Q07820,Q13614,Q96KB5,P16989,O75396,Q9NNW5,Q9NRR5,P09601,P60520,Q9H2J4,P67809,Q99729,P98175,Q08J23,P42345,Q9P275,P35637,P46379 23 +Regulation of anatomical structure size 0.2234436457046554 0.1371425402551206 0.8909181278561442 1.0 0.991506363105932 83 O95429,Q9UEY8,O96011,Q9NUT2,P07196,Q9UQB8,P35611,Q96F07,O94813,Q9HB40,P61586,Q9P265 12 +Dna integrity checkpoint signaling 0.2293344392690509 0.1363713131642287 0.8915277505709172 1.0 0.9918594599092212 33 P61254,Q9BXW9,P78527,Q9UNS1,Q6NUQ1,Q9HAW4,P38398,Q8WXE1,Q9Y619,Q96FV9,Q13564,P24941,P49959,O14757,P43246 15 +Maintenance of location in cell 0.2252564095977454 0.1358815484862279 0.8919149223475165 1.0 0.9921179011214084 38 P28161,O43731,Q96RL7,Q12955,Q07812,P24390,O94901,P78417,P35670 9 +Detoxification 0.229412774053757 0.1350377429857383 0.8925820330339351 1.0 0.9926875874332272 32 P28161,P00374,P10620,Q8TED1,Q6DKJ4,Q9Y5Z9,P78417,P35670 8 +Positive regulation of hydrolase activity 0.2219624369362696 0.1331010057780556 0.894113499729495 1.0 0.9932576352021772 80 Q14344,Q9UL46,Q8IZ81,Q13794,P31751,P40616,Q15555,Q92688,P42345,Q07812,Q96N67,Q96HY6,Q96F07,P61586,O95831,Q9P0J0 16 +Negative regulation of catabolic process 0.2193508959588283 0.1330243973644347 0.8941740856611338 1.0 0.9932576352021772 101 Q92804,P85037,Q14011,O75376,Q96KQ7,Q96HY6,Q07820,Q13614,Q96KB5,P16989,Q96HJ9,O75396,Q9NNW5,Q9NRR5,P09601,P60520,Q9H2J4,P67809,Q99729,P98175,Q08J23,P42345,Q9P275,P35637,P46379 25 +Cell cycle phase transition 0.2020263167976567 0.1328209257127466 0.8943350046590943 1.0 0.9932576352021772 130 Q9UJX2,Q6NUQ1,O43823,Q9Y619,Q8WXE1,Q96HY6,P83731,Q5JVF3,O00213,Q9UL46,P06730,Q00535,Q9BXW9,P61254,Q9UJX3,P50570,P31350,Q9H1A4,O43660,P38398,O75312,Q9UNS1,Q13564,Q7Z7L1,O00571,Q96K76,P11802,P78527,P49427,P14635,O60566,Q96FV9,O43684,Q9UJX4,Q16763,O14757,Q08J23,Q8IY18,P42771,Q96DY7,Q13616,Q9HAW4,P54652,Q9Y6G9,P49959,O43264,P50748,Q96FF9,P24941,O60216,P49321,P43246 52 +Cellular response to camp 0.341447581953917 0.1319895757728472 0.894992536938529 1.0 0.9938155991728578 4 Q9Y4G8,O60341,P27695 3 +Positive regulation of smooth muscle cell apoptotic process 0.3409779284915508 0.130813525204122 0.8959228233751908 1.0 0.9945038306257966 5 P42771,P98175 2 +Autophagosome maturation 0.2533592678606462 0.1304000207100531 0.8962499502063437 1.0 0.9946945913066246 16 Q99570,Q9NRR5,O95295,P51809 4 +Regulation of cell adhesion 0.221560436507886 0.1300002638335587 0.8965662179534626 1.0 0.9947529267077564 86 O15031,Q9NUQ9,Q5JRA6,P41440,Q13418,P30825,P50570,P23396,Q12955,Q08722,Q53GQ0,Q9HCM4,Q9HCL2,P61586,P46939,P04439,P80404,Q13277,Q96J02,O95429,P55196 21 +Chromatin disassembly 0.2747907836886923 0.1293731332617044 0.8970624055523984 1.0 0.995079094366868 13 Q12824 1 +Positive regulation of nucleobase containing compound metabolic process 0.1960449779987836 0.1286180309831923 0.8976598981544297 1.0 0.9951680186722124 384 Q8NB78,Q96T88,Q92804,Q03164,Q14011,P85037,Q86X55,Q9UH62,Q9BRX5,Q96HY6,Q13547,Q96B01,Q8IZL8,P41440,Q969T7,Q13418,Q9H7B4,P17480,Q9UNS1,Q86V81,P62487,Q8IWA0,P18887,P50570,P23396,Q9BZK7,Q9Y2X0,Q13868,P43490,Q92945,P51812,P14373,P50750,Q659A1,P98179,Q05086,Q68CP9,Q9NQT5,P67809,O75155,Q99729,Q07812,P61457,Q9NYF8,Q9BRT9,P51858,Q13492,O60244,P40938,Q9UBU8,Q96B26,Q99417,Q71SY5,Q9Y613,P42345,Q9HCE1,P35269,O00178,Q96T76,Q15427,O15514,Q3B7T1,Q8WUB8,P35637,P24941,P24468,Q9BXJ9,P49959,O96028,Q12824 70 +Regulation of phosphoprotein phosphatase activity 0.3334787807196454 0.1279515692103957 0.8981873000758018 1.0 0.9951680186722124 7 P67870,P42345 2 +Response to monosaccharide 0.2272297055485749 0.1277549951982893 0.8983428667522588 1.0 0.9951680186722124 29 P22059,P17480,P17858,Q14232,Q96RR1,O95563,Q13131,P17252,Q12824,Q9HCL2,P61586,Q15907 12 +Mitotic cell cycle phase transition 0.2155525266866274 0.1269218432297571 0.8990022580564789 1.0 0.9951680186722124 105 Q9UJX2,Q6NUQ1,Q9Y619,P83731,Q5JVF3,Q9UL46,P06730,Q00535,P61254,Q9UJX3,P50570,P31350,Q9H1A4,O43660,P38398,O75312,Q13564,Q7Z7L1,O00571,Q96K76,P11802,P49427,P14635,O60566,O43684,Q9UJX4,Q16763,O14757,Q8IY18,P42771,Q13616,Q9HAW4,P54652,Q9Y6G9,P49959,O43264,P50748,Q96FF9,P24941,P49321,O60216,Q96DY7 42 +Cristae formation 0.3144366867721382 0.1261589351794525 0.8996061165581444 1.0 0.9954874387064212 9 Q9NX63,Q9BUR5 2 +Protein localization to extracellular region 0.2158215543336206 0.1256105478935964 0.9000402130818819 1.0 0.9955212457220418 59 P30040,O00186,Q5JRA6,P17858,Q6IQ22,O00213,P43034,O95563,Q32P28,Q9UBV2,Q16850,Q15907,P61026,P80404,P49755,Q96PC5,Q6WKZ4,P55011,P22059,Q9Y5K6,P20645,P50416,Q9NV70,Q9Y678,Q13555,O00429,P53367,Q96QK1 28 +Cell cycle 0.1676959906191162 0.125439066133199 0.9001759620442575 1.0 0.9955212457220418 454 Q8NFH4,Q15392,Q9UHD1,Q14166,Q13432,P25205,O00410,Q9UQ84,Q96B01,Q99570,Q92538,Q14141,P50570,P23396,Q96IY1,Q9NNW5,Q96K76,Q9NQS7,Q9UJX4,O14757,Q08J23,O95373,P42771,Q9NVI1,Q9HAW4,P50748,P24941,Q12824,P49736,Q15555,Q9Y371,Q96HY6,Q96KB5,Q9NTJ3,O75935,Q9ULW0,Q00535,Q9UJX3,P31350,Q9H1A4,P38398,Q12955,Q15648,Q92733,Q9BXF3,P50750,Q96DB5,P49427,P14635,Q96FV9,Q15691,Q8N3U4,Q8IY18,Q8NFH3,Q8WWK9,Q9UBU8,Q9NY61,Q9H6H4,Q9Y6G9,Q2NKX8,Q68CZ6,P46379,Q96DY7,P49321,P43246,Q9UJX2,Q96T88,Q96EE3,Q6NUQ1,O43823,Q14203,P62244,Q5JVF3,Q03188,O94901,Q9BPX3,Q9BXW9,O75414,O43660,O75312,Q96ES7,P33993,P36405,Q13564,Q15813,Q5TKA1,P61586,P11802,Q92878,P11171,P08754,P53041,O60566,O14744,Q9H6D7,Q16763,Q15021,Q9Y5K6,Q8IX90,Q13616,P54652,P52732,O75376,Q9Y619,Q9BRX5,Q96KQ7,O14976,Q96CW5,Q9UL46,Q9UNS1,P31751,O75717,Q9BTE3,P78362,P51812,Q7Z7L1,Q07812,Q9Y2Z0,Q6DKK2,Q96FF9,P24468,P49959 122 +Dna conformation change 0.1997782805598643 0.1248108425574377 0.9006733033983703 1.0 0.9958082812512876 132 P55209,Q9H7B4,Q96JM7,Q96RR1,Q9NRG0,O43823,P25205,Q2NKX8,Q9BRX5,Q15047,Q9BRT9,Q13547,O95831,Q6IPU0,Q15021 15 +Cell division 0.2011715522683931 0.1239583779907491 0.9013482303709172 1.0 0.996382530415202 190 Q8NFH4,Q9UJX2,Q96EE3,Q15555,Q13432,Q01085,Q14203,Q9Y371,Q03188,Q99570,Q9NTJ3,O75935,Q9ULW0,Q00535,Q9BPX3,Q14141,Q9UJX3,Q9UNS1,Q9H1A4,P23396,Q12955,Q96ES7,Q96IY1,P36405,Q9BTE3,Q9BXF3,P61586,P11802,P67809,P11171,P14635,P08754,O60566,Q96N67,Q8N0X7,Q9NQS7,O43684,Q9UJX4,Q15691,Q9H6D7,Q16763,Q08J23,Q8N3U4,Q15021,Q8IY18,Q8NFH3,Q8WWK9,Q9Y5K6,Q9NY61,Q8IX90,Q9H6H4,Q6DKK2,P52732,Q9Y6G9,Q2NKX8,Q68CZ6,P50748,Q96FF9,P24941 59 +Positive regulation of cellular component organization 0.2005206050583837 0.1235283127192907 0.9016887556702152 1.0 0.9964145338794494 223 O15031,Q16625,Q15555,Q9Y371,Q9UQB8,Q15047,O94813,Q86YS7,P41440,Q9UJX3,Q32P28,P35611,P14373,Q08722,P61586,Q15021,Q96PU5,O95429,Q71SY5,Q13794,Q9C0E8,P07196 22 +Blastocyst growth 0.3010090667897127 0.1232692785313888 0.9018938674434476 1.0 0.9964145338794494 10 Q6PD62,O75312,Q9BRT9,O14757 4 +Regulation of cell cycle checkpoint 0.3125035173846273 0.123136059546535 0.9019993571599948 1.0 0.9964145338794494 9 P14635,Q9Y6G9,Q96FV9 3 +Regulation of glial cell differentiation 0.3118678869788393 0.1221574294022635 0.9027743403028266 1.0 0.996754985174062 9 Q13547,P42345 2 +Establishment of endothelial intestinal barrier 0.3292796528972282 0.1217542070716024 0.903093681504434 1.0 0.9968809578950116 7 P62820 1 +Mitotic cell cycle process 0.1993470351027588 0.1215971168589189 0.903218096959119 1.0 0.9968809578950116 226 Q13432,P25205,Q14141,P50570,Q96IY1,Q96K76,Q9NQS7,Q9UJX4,O14757,P42771,Q9HAW4,P50748,P24941,P49736,Q9NTJ3,Q9ULW0,Q00535,Q9UJX3,P31350,Q9H1A4,P38398,Q12955,Q96DB5,P49427,P14635,Q8N3U4,Q8IY18,Q8WWK9,Q9H6H4,Q9Y6G9,Q96DY7,P49321,P43246,Q9UJX2,Q96EE3,Q6NUQ1,Q14203,O43823,Q5JVF3,Q03188,Q9BPX3,Q9BXW9,O75414,O43660,O75312,P33993,P36405,Q13564,Q15813,P61586,P11802,O60566,O14744,O43684,Q16763,Q15021,Q13616,P54652,P52732,Q53HL2,O43264,O60216,P17252,Q9Y619,Q9BRX5,Q9P287,P83731,Q13561,Q9UL46,P06730,P43034,P61254,Q7Z7L1,O00571,P63096,P78527,Q6DKK2,Q96FF9,P49959 79 +Brown fat cell differentiation 0.3345241961675919 0.1212274247210409 0.9035109025192692 1.0 0.9968809578950116 6 Q92766,Q02252,Q6IAN0,Q9C0B1,Q00839 5 +Cellular response to toxic substance 0.2235790276964929 0.1206938941562587 0.9039334953985548 1.0 0.9968978829052216 31 P28161,P00374,P10620,Q8TED1,Q9Y5Z9,P78417 6 +Positive regulation of small molecule metabolic process 0.2540235781684844 0.1203814705837213 0.9041809689833706 1.0 0.9968978829052216 15 P50416,Q13794 2 +Regulation of histone modification 0.214678283143233 0.1193247816328731 0.9050180508561878 1.0 0.9969576143040166 63 Q03164,O43823,Q96ES7,Q96KQ7,P50750,Q9NY27,Q12824 7 +Cardiac septum morphogenesis 0.3329982020709318 0.1192874974307666 0.905047588377698 1.0 0.9969576143040166 5 O94813 1 +Positive regulation of peptidyl threonine phosphorylation 0.3320350535540456 0.1183783146739664 0.9057679073350032 1.0 0.9972636773047704 4 P53350,Q9Y376,P61086 3 +Regulation of peptidyl threonine phosphorylation 0.3321428571428624 0.1181089124476604 0.9059813617711764 1.0 0.9972636773047704 5 P61086,Q9Y376,Q04637,P53350 4 +Mitochondrial fission 0.2681438452525314 0.1176005030540807 0.9063842063336796 1.0 0.9972636773047704 13 O60313,Q9UDX5,Q9NUQ9 3 +Cellular response to thyroid hormone stimulus 0.2936404931862337 0.1175686717873758 0.906409429039568 1.0 0.9972636773047704 3 P48506,Q15648 2 +Cellular response to interleukin 1 0.3196249974889135 0.1172046875121792 0.9066978524259826 1.0 0.9972636773047704 8 Q92900,P38159,Q08722 3 +Regulation of neural precursor cell proliferation 0.2575159200389237 0.1170560602266637 0.9068156291445968 1.0 0.9972636773047704 14 P61586,Q13418 2 +Mrna transport 0.2162075625086265 0.1163054793005742 0.907410443231665 1.0 0.9972882813688382 76 Q8NFH4,Q96EE3,Q7KZ85,Q96J01,Q5JVF3,Q9UN86,Q96MU7,P63241,Q86V81,Q92945,Q86U42,Q6P6C2,Q92900,Q16629,Q96FV9,Q8WUM0,Q9Y6M1,Q8NFH5,P51991,Q08J23,Q8NFH3,O15514,Q53F19,O75694,O75152,Q12769 26 +Terpenoid biosynthetic process 0.3303144493405164 0.1160326053149081 0.9076267010109532 1.0 0.9972882813688382 4 P48449,P14324 2 +Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.2962602340723057 0.1158792659490125 0.9077482283560184 1.0 0.9972882813688382 10 P46379 1 +Actin polymerization dependent cell motility 0.3300876338851072 0.1157266413505168 0.9078691913647784 1.0 0.9972882813688382 4 P61158,O15145,Q8N8S7 3 +Glycolipid biosynthetic process 0.2957830640089719 0.1151618116925826 0.9083168670909548 1.0 0.997392393777383 10 Q13131,Q969N2,Q92643,O60762 4 +Vesicle docking involved in exocytosis 0.324568725853999 0.1151402705244828 0.9083339408831176 1.0 0.997392393777383 7 P56545,Q6IQ22,P61026 3 +Positive regulation of mononuclear cell migration 0.3173572339843551 0.1140183280161958 0.9092232645349556 1.0 0.998197811929893 8 Q08722 1 +Regulation of cellular component biogenesis 0.1973276601550852 0.1136106580923051 0.909546438124572 1.0 0.9982684329219772 200 Q16625,Q9NUQ9,Q15555,Q9Y371,Q9UQB8,Q96KQ7,Q15047,Q969V3,O94813,P41440,Q6PD62,P35611,Q08722,O75396,Q9HCM4,P61586,Q96JM7,Q9Y4F1,Q8WXH0,Q07812,Q96F07,O95429,Q9UEY8,P51114,Q71SY5,Q9Y613,P54652 27 +Response to endogenous stimulus 0.1879716569536795 0.1131929515876569 0.9098775835727796 1.0 0.9982684329219772 256 Q15392,Q9HCD5,Q5JRA6,O75376,Q86X55,O43823,Q9BSK2,Q9UQB8,Q96HY6,Q96KQ7,Q6IQ22,Q13547,O94813,Q8IZL8,Q9C0C9,Q86YS7,P42785,Q13418,Q9H7B4,Q9UNS1,P31751,P43490,P08574,O00400,P09601,Q9HCM4,P61586,P11802,Q05086,Q96A49,Q9NUQ7,Q99729,O43865,O95831,O95429,P42345,P33121,P07196,O75874 39 +Establishment of organelle localization 0.1987480994182001 0.1126670534193537 0.9102945224530076 1.0 0.9983473225190832 120 Q96A57,Q96EE3,P51809,Q9UH62,O95295,O94901,Q92538,Q00535,O75381,P50570,P61221,P09601,Q15907,Q96DB5,O94832,Q8WXH0,P14635,Q96N67,Q9NQS7,Q13492,P62841,Q8IXI1,Q9Y613,P07196,Q9HAS0,P62820,Q96FF9,O60313 28 +Positive regulation of cell cycle g1 s phase transition 0.2437389873416248 0.1120738615146044 0.9107648423224242 1.0 0.9985865619589264 16 Q96HY6 1 +Regulation of jun kinase activity 0.3273392512902151 0.1116922998079512 0.9110673849891624 1.0 0.9985865619589264 5 P23396,P31689 2 +Viral genome replication 0.2133948725615392 0.1105836225118306 0.9119465351655348 1.0 0.9985865619589264 44 Q15047 1 +Regulation of glucose transmembrane transport 0.2916405111623264 0.1091235524069758 0.913104494319778 1.0 0.9985865619589264 10 Q86YS7,Q16625,P31751 3 +Cellular response to organic cyclic compound 0.2108293589984766 0.108626569772707 0.913498685819885 1.0 0.9985865619589264 101 Q9H7B4,Q9NUQ7,O75376,Q9NUD5,Q86X55,Q96KQ7,Q96HY6,O95831,P41440,P61586,P11802,Q05086 12 +Peptide metabolic process 0.1403657469572781 0.1080271848644553 0.9139741279887532 1.0 0.9985865619589264 366 P26640,Q5VV42,Q969T7,Q8WU17,P62487,Q16799,P23396,Q92945,P98179,Q9NQT5,P67809,Q05639,P55786,Q8TB36,Q9Y6M1,Q13492,Q9Y6E2,Q96B26,Q9Y2R9,Q9HCE1,Q5JPH6,Q567V2,Q8N983,Q9NSE4,O15031,P60228,P00390,P82914,Q8WU90,P52888,Q7L576,P05198,O15372,P61221,P16989,Q96E11,P78417,P26196,P55010,Q15024,Q96C86,Q5JTZ9,P62841,P23588,Q96P11,O75874,Q5T160,O15514,O95363,O95453,P18621,P19525,P49458,Q9P2J5,Q9Y262,Q8TAD4,Q14011,Q71RC2,P08708,P00374,Q13868,P46783,P61586,Q9NZ08,Q9NQC3,P61009,O75822,P62263,Q10713,Q9BYT8,P67812,P31751,P51812,O95182,Q13217,O15371,P51114,P42345,P28161,O00178,Q9Y3U8 81 +Negative regulation of mrna processing 0.2268866810735282 0.1078374142021997 0.9141246636875804 1.0 0.9985865619589264 23 Q6PD62,Q16629,P98175,P50750,P38159 5 +Positive regulation of metaphase anaphase transition of cell cycle 0.3188303299619059 0.1075607393403256 0.914344141716518 1.0 0.9985865619589264 7 Q9UJX4,Q9UJX3 2 +Regulation of ubiquitin protein transferase activity 0.2267360866842937 0.1075592817439909 0.9143452980021224 1.0 0.9985865619589264 23 O60566,P62841,Q16763 3 +Aspartate family amino acid metabolic process 0.2300943061832629 0.1062090120818571 0.9154165207853552 1.0 0.9985865619589264 21 Q13126,P30520 2 +Regulation of immunoglobulin production 0.2444147007400922 0.104016682752894 0.917156109462916 1.0 0.9985865619589264 15 Q96FV9,P55061,O96028,Q9NQT5 4 +Cellular response to endogenous stimulus 0.1914784567563377 0.103896446266151 0.9172515273149722 1.0 0.9985865619589264 207 Q8TBX8,Q9P2J5,Q9HCD5,O75376,Q86X55,O43823,Q9BSK2,Q13131,O00410,Q9UQB8,Q96HY6,Q15185,Q6IQ22,O60343,O94813,Q9C0C9,Q8IZL8,Q86YS7,Q13547,P42785,Q7L576,Q00535,Q13418,Q9H7B4,O95071,P62993,P50570,Q9UNS1,O15164,P31751,P38398,O75312,Q15648,P20020,P33993,P43490,Q8NC56,O00400,Q9HCM4,P61586,P11802,Q05086,O14654,Q96A49,O60763,Q9Y2Q5,Q9NUQ7,Q99729,P08754,O14744,Q8N0X7,O43865,P41240,O95831,O14757,O95429,P61981,Q96KQ7,P42345,P33121,P28161,Q9BZF1,Q96QK1 63 +Cellular response to dna damage stimulus 0.1898198438688462 0.103718978770111 0.9173923650055568 1.0 0.9985865619589264 225 Q15291,Q96T88,Q6NUQ1,P49736,P25205,P46063,Q07820,Q9UQ84,Q96B01,Q9NY27,P41440,Q9BXW9,O95071,Q9UNS1,P29372,P23396,P18887,O75717,Q9Y2K7,P50750,Q7Z7L1,Q9HBM6,P09601,Q96K76,Q9NRR5,Q68CP9,P83916,Q07812,Q9BQP7,Q9NYF8,Q9BRT9,O96028,O14757,P40938,Q9UBU8,P51114,Q13794,Q9HAW4,Q96T76,P49005,P35637,P24941,Q9GZR2,Q96FF9,P46379,P49959,Q96S55,Q96SB8 48 +Dna repair 0.1936029191836537 0.1036857105994718 0.917418766818038 1.0 0.9985865619589264 166 Q96T88,P25205,P46063,Q9UQ84,Q96B01,Q9NY27,P41440,Q9BXW9,Q9UNS1,P29372,P23396,P18887,O75717,Q9Y2K7,P50750,Q9NRR5,Q96K76,Q68CP9,Q9BQP7,Q9BRT9,O96028,O14757,P40938,Q9UBU8,Q9HAW4,Q96T76,P49005,P35637,P24941,Q9GZR2,Q96FF9,P49959,Q96S55,Q96SB8 34 +Hormone metabolic process 0.2147105798201693 0.1034420058003794 0.9176121751302752 1.0 0.9985865619589264 30 Q53GQ0,Q9HB40 2 +Negative regulation of mitotic cell cycle phase transition 0.2110200504404812 0.1031809134177093 0.9178193879369988 1.0 0.9985865619589264 39 Q6NUQ1,Q9Y619,Q5JVF3,P61254,P38398,Q13564,Q7Z7L1,Q96K76,P14635,O60566,O43684,O14757,Q9HAW4,Q9Y6G9,O43264,P50748,P24941,O60216,P49959 19 +Cell cycle process 0.1710681311491039 0.1030407870346616 0.9179305998463176 1.0 0.9985865619589264 323 Q9UHD1,Q13432,P25205,Q96B01,Q99570,Q14141,P50570,P23396,Q96IY1,Q9NNW5,Q96K76,Q9NQS7,Q9UJX4,O14757,Q08J23,P42771,Q9HAW4,P50748,P24941,P49736,Q15555,Q9Y371,Q96HY6,Q9NTJ3,O75935,Q9ULW0,Q00535,Q9UJX3,P31350,Q9H1A4,P38398,Q12955,Q15648,Q9BXF3,Q96DB5,P49427,P14635,Q96FV9,Q15691,Q8N3U4,Q8IY18,Q8WWK9,Q9H6H4,Q9Y6G9,Q68CZ6,P46379,P49321,Q96DY7,P43246,Q9UJX2,Q96EE3,Q6NUQ1,O43823,Q14203,Q5JVF3,Q03188,O94901,Q9BPX3,Q9BXW9,O75414,O43660,O75312,P33993,P36405,Q13564,P61586,P11802,O60566,Q9H6D7,Q16763,Q15021,Q13616,P54652,P52732,O75376,Q9Y619,Q9BRX5,Q96KQ7,Q96CW5,Q9UL46,Q9UNS1,Q9BTE3,Q7Z7L1,Q6DKK2,Q96FF9,P49959 86 +Face development 0.3201298701298813 0.1026982901366443 0.9182024307437416 1.0 0.9985865619589264 5 Q12797,P28482,Q6KC79,Q15042 4 +Regulation of mrna metabolic process 0.1918411249573787 0.1025204822122996 0.9183435560501908 1.0 0.9985865619589264 147 Q9H0G5,Q92804,Q14011,Q8IY67,Q9NR56,Q7L8L6,Q5JVF3,Q969T7,Q6PD62,P62487,P16989,Q13868,Q92945,P78362,P50750,Q13595,P38159,P98179,Q6P6C2,P67809,Q9NQT5,Q99729,Q16629,Q15024,Q96C86,O43865,P98175,O75525,P51114,Q96B26,Q9HCE1,O00178,Q15427,O15514,Q13242,O95453,P35637 37 +Protein folding in endoplasmic reticulum 0.286455686304346 0.102040093585119 0.9187248510775412 1.0 0.9985865619589264 10 Q8IXB1 1 +S adenosylmethionine metabolic process 0.3188570381766 0.101061965347706 0.91950127066974 1.0 0.9985865619589264 6 O43865,Q86W50 2 +Positive regulation of extrinsic apoptotic signaling pathway 0.2851998090939018 0.1004022701942168 0.9200249675212702 1.0 0.9985865619589264 10 Q13794 1 +Secretion 0.1888080614036443 0.0997357389801695 0.9205541263856396 1.0 0.9985865619589264 142 Q5JRA6,P51809,Q13505,Q6IQ22,Q15758,O15126,Q32P28,Q9UBV2,P09601,Q13277,O43760,O00471,Q96PC5,Q6WKZ4,Q9Y5K6,P20645,P50416,Q13555,Q9BRK5 19 +Organelle localization 0.1903033844882292 0.0993628894305516 0.920850146851894 1.0 0.9985865619589264 158 Q96A57,Q96EE3,P51809,Q9UH62,O95295,O43752,O75153,Q6IQ22,O94901,Q00535,Q92538,O75381,P50570,P61221,Q9BZG1,Q9H267,P09601,O00161,Q15907,Q96DB5,O94832,Q8WXH0,P14635,Q13277,Q96N67,Q9NVT9,Q9NQS7,O43865,Q13492,P62841,Q9BUK6,Q8IXI1,P42345,Q9Y613,P07196,Q9HAS0,P62820,Q96FF9,O60313 39 +Endoderm development 0.2458641548851635 0.0986010636923766 0.9214550254339312 1.0 0.9985865619589264 14 Q6PD62,Q13547 2 +Regulation of lymphocyte activation 0.2036792430705939 0.0969339446263458 0.9227788518149764 1.0 0.9985865619589264 50 P30825,Q9BXW9,Q9NUQ9,Q9NQT5,P23396,Q96J02,O96005,Q08722,O96028,Q9HCL2,P61586 11 +Response to cytokine 0.1845290252182164 0.0964607112072439 0.9231546762870272 1.0 0.9985865619589264 136 P49736,Q14166,Q07820,Q8WU90,O94813,Q13418,Q6PD62,P78318,Q96RT1,P23396,P38398,Q15648,P16989,Q92945,Q08722,P50750,P38159,P61586,P11802,Q9Y5A7,P67809,P49427,Q16629,Q9NYF8,P51858,Q14145,Q8NFH5,P55011,O95429,P33121,Q9P0J0 31 +Positive regulation of posttranscriptional gene silencing 0.272351461933484 0.0955842492379367 0.923850775203386 1.0 0.9985865619589264 11 P51114,Q01085 2 +Leukocyte cell cell adhesion 0.2079812847334135 0.0955037738549248 0.9239146928609604 1.0 0.9985865619589264 35 P30825,Q9NUQ9,Q5JRA6,P23396,Q96J02,Q08722,Q9HCL2,P61586 8 +Rac protein signal transduction 0.2811287212053672 0.0952981336199172 0.9240780250643876 1.0 0.9985865619589264 10 P63000,P50570,Q7L576 3 +Negative regulation of cellular macromolecule biosynthetic process 0.2076186163806642 0.0944642282461419 0.9247403970663536 1.0 0.9985865619589264 93 P60228,Q14011,Q10713,Q969T7,P05198,Q8WU17,P62487,Q9UNS1,P00374,P23396,Q13868,Q92945,Q7Z7L1,P26196,P67809,Q9NQT5,Q15024,Q96C86,Q9Y6M1,O14757,P51114,Q96B26,Q9NY61,Q9HCE1,O15514,O95453,P19525 27 +Tight junction organization 0.2427615766773934 0.0942844050801633 0.9248832376697464 1.0 0.9985865619589264 14 Q16625,O43815 2 +Ribosomal small subunit assembly 0.2521899128060321 0.0938264747537852 0.9252470006391385 1.0 0.9985865619589264 13 P78527,Q9Y2R9,O75616,P62841,Q9Y3A4,P62263 6 +Positive regulation of gene expression 0.1797030841836169 0.0935875359740582 0.925436811007198 1.0 0.9985865619589264 207 O15031,Q16625,Q9NUQ9,Q92804,P60228,Q14011,O75376,Q71RC2,Q13131,Q96HY6,Q13547,P41440,P63241,O95071,P62487,O15164,P23396,P38398,Q12955,Q15648,P16989,Q9NUD5,P78362,P14373,P09601,Q13595,P38159,P98179,P61586,Q9H2J4,P04439,P67809,Q9NQT5,Q99729,Q13217,O15371,O14802,P98175,O14757,Q9UJZ1,Q99943,Q96P11,P51114,P42345,O95816,Q567V2,Q15427,O15514,P54619,P62820,P35637,P19525,P55196,O96028,P43246,Q96QK1 56 +Cytokine production 0.2085588046995438 0.0934354110038491 0.9255576596412248 1.0 0.9985865619589264 86 Q9Y5K6,Q9NUQ9,P09601,P04439,Q96RT1,P23396,Q9NUD5,O43823,Q96J02,P09525,P62820,O14802,P14373,Q08722,Q9UJZ1,Q9Y385,P41440,Q9HCL2 18 +Regulation of stem cell differentiation 0.2514854709667363 0.0929162788036833 0.925970073080203 1.0 0.9985865619589264 13 Q8WX92,Q96J02,P19525,Q08J23,O43809 5 +Protein targeting to vacuole 0.2700049725251677 0.092697566014491 0.9261438307258454 1.0 0.9985865619589264 11 Q96RL7,P20645 2 +Positive regulation of cellular response to insulin stimulus 0.311044052072519 0.0926838015126951 0.926154766132156 1.0 0.9985865619589264 4 P04899,Q9BZF1 2 +Protein adp ribosylation 0.2996425089372634 0.0920632798332399 0.9266477629595232 1.0 0.9985865619589264 8 P18085,Q9H2P0,P18887,Q7Z2W4,P09874,P23381,Q15397 7 +Response to isoquinoline alkaloid 0.2748215444516489 0.091729530536631 0.9269129343226444 1.0 0.9985865619589264 3 P63151,P53041 2 +Mature ribosome assembly 0.3097402597402702 0.0910440322331067 0.9274576036546331 1.0 0.9985865619589264 5 O00571,P56537,Q7Z2Z2,Q9Y3A5 4 +Positive regulation of granulocyte chemotaxis 0.3097402597402686 0.0910440322331051 0.9274576036546344 1.0 0.9985865619589264 5 Q8NHP6,Q8NE86,P63000,O00429 4 +Positive regulation of neutrophil migration 0.3097402597402686 0.0910440322331051 0.9274576036546344 1.0 0.9985865619589264 5 Q8NHP6,Q8NE86,P63000,O00429 4 +Cell cycle checkpoint signaling 0.2017253234175899 0.0906579087502429 0.9277644167995708 1.0 0.9985865619589264 48 Q6NUQ1,Q8WXE1,Q9Y619,Q5JVF3,P61254,Q9BXW9,Q9UNS1,P38398,Q13564,P14635,O60566,Q96FV9,O43684,O14757,Q08J23,Q9HAW4,Q9Y6G9,O43264,P50748,P24941,P49959,P43246 22 +Response to peptide hormone 0.2067838131878584 0.090592941227915 0.9278160409529588 1.0 0.9985865619589264 75 Q8TBX8,Q9HCD5,Q9BSK2,Q13131,Q9UQB8,Q6IQ22,O60343,Q86YS7,Q7L576,P62993,P31751,P43490,P08574,Q96A49,P11802,O14654,O60763,O43865,P41240,P61981,P42345,P07196,Q9BZF1 23 +Response to interleukin 7 0.2875937075374802 0.090262385350133 0.9280787102399886 1.0 0.9985865619589264 9 P51858,P67809 2 +Organelle assembly 0.1635024941847619 0.0895682786090176 0.9286302930592308 1.0 0.9985865619589264 210 Q9Y5K8,Q8TBX8,Q14011,Q15555,O75376,Q9Y371,Q96KQ7,Q9UN86,Q96CW5,Q9BRG1,Q9ULW0,Q96J42,Q92538,P05198,Q14141,P50570,P50851,P23396,A0AVF1,Q9BZG1,O75396,P61586,P60520,Q14315,Q8WXH0,Q9NQS7,Q9H6D7,Q9NVR5,O00471,P62841,Q9Y679,Q8N3U4,A6NIH7,Q9Y2R9,P52732,Q567V2,P62820,P50748,P24941,P62263,Q9NVG8 41 +Purine nucleoside monophosphate metabolic process 0.2213164111139032 0.0889076577541453 0.929155297648429 1.0 0.9985865619589264 20 P49902,P30520 2 +Microtubule based process 0.1609427660773122 0.0881442765475573 0.9297620057096168 1.0 0.9985865619589264 189 Q16625,Q9UHD1,O75376,Q15555,Q9UH62,O95295,Q96CW5,O75935,Q9ULW0,O94901,Q00535,O75381,P78318,P63000,P29372,P23396,Q96RL7,A0AVF1,P38398,P61586,Q96DB5,Q03001,P14635,Q8WXH0,Q96N67,Q9NQS7,Q9H6D7,Q9NVR5,Q15691,Q96P70,O14757,Q8N3U4,Q8WWK9,Q8IXI1,Q8IX90,P07196,P52732,Q9Y6G9,P62820,P24941,Q99653,O60313 42 +Cytoplasmic sequestering of protein 0.2853457585000667 0.0878261967811347 0.9300148161932218 1.0 0.9985865619589264 9 Q14145 1 +Cortical actin cytoskeleton organization 0.2222149523398664 0.0877095284708281 0.9301075461892514 1.0 0.9985865619589264 17 Q9Y613,P11171,Q9Y2J2,Q14651,Q00535 5 +Regulation of synaptic transmission glutamatergic 0.3060694579681972 0.0875000833781664 0.9302740191606014 1.0 0.9985865619589264 4 Q8NBU5,Q00535,Q15042 3 +Regulation of ruffle assembly 0.2941176470588119 0.086238720047378 0.9312766511980076 1.0 0.9985865619589264 8 Q9ULV4,P84095,P35080,Q8NCA5,Q9P258,Q7L576,P07737 7 +Srp dependent cotranslational protein targeting to membrane 0.2725449177235641 0.0855349430936016 0.9318361166802358 1.0 0.9985865619589264 10 P61619 1 +Endocytic recycling 0.2169900268550281 0.0853186954000237 0.932008028944454 1.0 0.9985865619589264 21 Q9UBQ0,Q567U6,Q15907,O43752 4 +Tubulin complex assembly 0.3038961038961085 0.0851438328382954 0.9321470432389176 1.0 0.9985865619589264 5 Q15813,P17987,O75347,Q9BTW9 4 +Spindle organization 0.2034242432180225 0.0849825444229115 0.9322752680340418 1.0 0.9985865619589264 71 Q96DB5,O75376,Q15555,P14635,P52732,Q9H6D7,Q8N3U4,P61586 8 +Nucleotide phosphorylation 0.201024279748011 0.0847972412520839 0.93242258680428 1.0 0.9985865619589264 34 P85037,Q02218,Q9BRR6,O75414 4 +Oligosaccharide lipid intermediate biosynthetic process 0.292670588712603 0.0847898946377728 0.932428427519403 1.0 0.9985865619589264 8 Q9BT22,Q96AA3 2 +Non membrane bounded organelle assembly 0.1484630728182591 0.0833809601560353 0.9335486273814928 1.0 0.9985865619589264 136 P10644,Q14011,Q15555,O75376,Q13131,Q9P287,P83731,Q9UN86,Q03188,P62750,Q96CW5,Q9ULW0,P05198,Q9BPX3,P23396,P38398,O75616,Q14651,O00571,P61586,P28289,P26196,P78527,Q14315,Q9NQS7,Q9H6D7,Q15691,P62841,Q9Y679,Q8N3U4,P27635,Q9Y2R9,P53350,P52732,P62266,Q68CZ6,Q567V2,P50748,P24941,Q9Y3A4,P62263 41 +Positive regulation of catecholamine metabolic process 0.3010579515999942 0.0826126378966581 0.9341595520395324 1.0 0.9985865619589264 4 P80404,Q96QK1 2 +Positive regulation of cellular amine metabolic process 0.3010579515999942 0.0826126378966581 0.9341595520395324 1.0 0.9985865619589264 4 P80404,Q96QK1 2 +Positive regulation of cell cycle checkpoint 0.3009426705301694 0.0825040924361242 0.934245864138197 1.0 0.9985865619589264 4 Q9Y6G9 1 +Positive regulation of cell population proliferation 0.1843907054508203 0.0821680156426284 0.9345131072340958 1.0 0.9985865619589264 113 Q86X55,Q01085,Q9BSK2,Q96HY6,Q13547,Q13418,P30825,P31751,P23396,P43490,P78362,Q08722,P09601,Q9HCL2,P11802,Q9H2J4,P14635,Q13277,Q9NQC3,P49006,P55209 21 +Protein o linked glycosylation 0.2278718605184632 0.0817528192165518 0.9348432752319432 1.0 0.9985865619589264 15 Q02809,O60762,O60502,Q7Z4H8,O00469 5 +Ribonucleoside monophosphate metabolic process 0.2121436961649139 0.081629423683974 0.9349414026516378 1.0 0.9985865619589264 22 P49902,P30520 2 +Positive regulation of dna biosynthetic process 0.2024198822759926 0.08130053739475 0.9352029466274518 1.0 0.9985865619589264 27 P28482,P48643,Q9BRX5,Q15185,P07900,O15381,P78371,P17987,P12004,P35222,P40937,Q99832,P50991,P08238,Q9BRT9,P40938,P50990,P49368,P40227,Q96HR8,P09651,P13010,O95453,P35249,O60832,Q96GD4 26 +Protein localization to endosome 0.2940220922677064 0.0805390539955064 0.9358085365058926 1.0 0.9985865619589264 7 Q15286,Q14160,P15311,P26038,P62330,Q96QK1 6 +Barbed end actin filament capping 0.2780082336663009 0.0804450228601391 0.9358833198447484 1.0 0.9985865619589264 9 Q9UEY8 1 +Histone monoubiquitination 0.2495682153481908 0.0800530471812015 0.9361950657599034 1.0 0.9985865619589264 12 Q6PD62,Q96T88 2 +Negative regulation of metaphase anaphase transition of cell cycle 0.2301571128265376 0.079158189822371 0.9369067998814786 1.0 0.998824236473932 14 P14635,Q9Y6G9,O60566,O43684,O43264,P50748,Q5JVF3 7 +Response to platelet derived growth factor 0.2904610350166902 0.0773820174141282 0.9383196459082216 1.0 0.9988556873018368 7 Q13547 1 +Regulation of microtubule polymerization 0.2128500723108571 0.0764658784329938 0.939048459536222 1.0 0.9992598723902058 18 Q16625,P63000,P23396,Q14203,Q15691 5 +One carbon metabolic process 0.2455527862558019 0.0761309163196103 0.9393149438418148 1.0 0.9993774340226982 12 P00374 1 +Multivesicular body organization 0.2884990253411306 0.0757151549562211 0.9396457186931516 1.0 0.9993973890002206 7 O43633,Q96FZ7,Q9BRG1,Q8WUX9,Q99816,Q8WUM4 6 +Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.2884990253411307 0.0757151549562211 0.9396457186931516 1.0 0.9993973890002206 7 Q8WUX9,O43633,Q9NZ09,Q96FZ7,Q9BRG1,Q99816 6 +Positive regulation of intracellular steroid hormone receptor signaling pathway 0.2918831168831259 0.0744240089881298 0.9406730053664464 1.0 0.99952777528499 5 Q15648,Q16512,Q13309,P09874 4 +Positive regulation of release of cytochrome c from mitochondria 0.2865120697009304 0.0740786638669975 0.9409477923741288 1.0 0.99952777528499 7 Q96A26,Q07812,Q13794 3 +Nucleoside monophosphate metabolic process 0.1898803440894663 0.0733804511045404 0.9415033734096232 1.0 0.99952777528499 29 P04183,O43598,P49902,Q00013,P30520 5 +Regulation of cellular amine metabolic process 0.2901984792865268 0.0731324110652316 0.9417007504034842 1.0 0.99952777528499 6 P80404,Q96QK1,P00492 3 +Regulation of nitric oxide synthase activity 0.2900863551148789 0.0730441454216861 0.9417709883450308 1.0 0.99952777528499 6 P00374 1 +Protein localization to cell periphery 0.198010071466404 0.0723640534145564 0.9423121909874316 1.0 0.99952777528499 76 O95429,Q8N2H4,P31751,P98194,Q12955,Q13277,Q9BZG1,Q9Y2J2,Q6IQ22,O00471,O14976,P55196,Q86YS7,P41440 14 +Negative regulation of innate immune response 0.2783555418162765 0.072092075132661 0.9425286329444942 1.0 0.99952777528499 8 Q14166 1 +Perk mediated unfolded protein response 0.2885858086582158 0.0718465103479861 0.9427240585273148 1.0 0.99952777528499 4 P05198 1 +Integrated stress response signaling 0.2885858086582158 0.0718465103479861 0.9427240585273148 1.0 0.99952777528499 4 P05198 1 +Positive regulation of viral life cycle 0.2883116883117029 0.0715862602033044 0.9429311747893656 1.0 0.99952777528499 5 P52292,Q99816,Q06787,P07237 4 +Nucleoside diphosphate metabolic process 0.1891088117770709 0.0709718775890006 0.9434201374672796 1.0 0.99952777528499 44 Q9BRR6,P17858,O75414,Q00013,P85037,O75376,P54619,Q02218,Q9BW91 9 +Histone deubiquitination 0.2566566406913751 0.0708025752876916 0.9435548821877529 1.0 0.99952777528499 10 Q9P275,Q96ES7 2 +Regulation of catecholamine metabolic process 0.2870904247201929 0.0706511792936529 0.9436753769616713 1.0 0.99952777528499 5 P80404,Q96QK1 2 +Tetrahydrofolate metabolic process 0.2557797067313154 0.0701069702693533 0.9441085188828744 1.0 0.99952777528499 10 P00374 1 +Viral translational termination reinitiation 0.2861573801609359 0.0700471225021103 0.9441561533870566 1.0 0.99952777528499 6 O15371 1 +Nadh regeneration 0.2801220058105314 0.0691580946986586 0.9448637787908718 1.0 0.99952777528499 7 P85037 1 +Protein localization to cytoskeleton 0.2193500122827411 0.0690182023407903 0.9449751306750648 1.0 0.99952777528499 14 Q15555,Q15691,O15344,P29372 4 +Positive regulation of dna metabolic process 0.1956326684626514 0.0689072878072882 0.9450634174792112 1.0 0.99952777528499 80 Q9BRX5,Q15185,Q96B01,Q9UNS1,P23396,P38398,P18887,Q68CP9,Q9NQT5,Q07812,Q9BRT9,P40938,Q9UBU8,Q96T76,O95453,P35637,P24941,P49959,O96028,P43246 20 +Response to peptide 0.1940710891804147 0.068882526194832 0.9450831275549212 1.0 0.99952777528499 86 Q8TBX8,Q9HCD5,Q9BSK2,Q13131,Q9UQB8,Q6IQ22,O60343,Q86YS7,Q7L576,Q00535,Q96RT1,P62993,Q9UNS1,P31751,P43490,P08574,Q96A49,P11802,O14654,O60763,O43865,P41240,P61981,P42345,P07196,Q9BZF1 26 +Rna mediated gene silencing by inhibition of translation 0.2844155844155936 0.0686648054242352 0.9452564332588496 1.0 0.99952777528499 5 Q9BWF3,P26196,P56537,Q04637 4 +Regulation of translation at synapse modulating synaptic transmission 0.2842103332539502 0.0685198834926549 0.94537179253354 1.0 0.99952777528499 4 Q7L576 1 +Negative regulation of developmental process 0.1917188385414779 0.0683966729157833 0.945469870258626 1.0 0.99952777528499 90 P57105,Q86X55,Q8N4Q0,Q13547,Q00535,Q9P265,Q6PD62,Q15648,P16989,Q6W2J9,Q9H6W3,P61586,Q05086,P26196,P67809,Q92688,Q8WX92,Q96FV9,Q8N0X7,Q9NQC3,Q4VCS5,Q9NQ29 22 +Mitotic g1 s transition checkpoint signaling 0.2830891218536477 0.0677107295067327 0.9460159080044735 1.0 0.9996994237341896 5 P61254,P78527,P24941 3 +Response to carbohydrate 0.1793117500650996 0.0653748982849374 0.9478755095824588 1.0 1.0 35 P17480,P17858,Q96RR1,Q5KU26,Q13131,Q12824,Q9HCL2,P61586,Q15907 9 +Cytoplasmic translation 0.1326118698569731 0.0642936165680185 0.948736436181318 1.0 1.0 105 O75534,P62424,Q13347,P61353,P49588,P23396,P62269,P39023,P11940,P30050,P32969,Q02543,Q14103,P60842,P67809,P62910,P62913,P55039,Q9BWF3,P05388,P08865,Q9Y295,P18077,P61513,Q02878,P62249,P62241,P46779,Q8WU90,P62277,P39019,P62280,P16989,P18124,P62495,P42766,Q14152,P62847,P55010,P25398,P62841,P23588,P15170,P62888,P46781,P60866,P18621,O60506,P46782,P47914,P26373,P62081,P62701,Q9NR50,P62244,P08708,Q9UET6,P83881,P62851,P62906,P62753,P41214,P46783,Q9NZI8,P63220,P40429,Q06787,P46776,P56537,Q9H2U1,O43583,P62917,P20042,P62263,P35268,P49207,P61927,P62829,Q07020,P83731,Q14240,P62750,P61254,P62273,P63173,Q04637,P84098,Q08211,P61313,P14618,P15880,Q7L2H7,P36578,P46777,P46778,O15371,P27635,P42345,P62266,Q9Y3U8,Q00839 101 +Regulation of protein localization to cell cortex 0.2777518673419089 0.0640741246541301 0.9489112050330852 1.0 1.0 5 P11171,P63096 2 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.2760572202388744 0.0631666633759261 0.9496337905189316 1.0 1.0 6 P61254,O60341,Q9HBM6 3 +Peptidyl serine dephosphorylation 0.2759740259740363 0.0629329883962889 0.9498198659581618 1.0 1.0 5 P63151,P53041,P30153,P62258 4 +Negative regulation of endoplasmic reticulum calcium ion concentration 0.2758330445403648 0.062763498652814 0.9499548323920723 1.0 1.0 4 Q07812 1 +Sister chromatid cohesion 0.1719087082239907 0.0624045413981381 0.950240678498296 1.0 1.0 30 Q9BTE3,Q8N3U4,O60566,Q96FF9 4 +Positive regulation of intracellular transport 0.1903270865748325 0.061722994346167 0.9507834280392417 1.0 1.0 68 Q9Y282,P31751,Q9UHD1,Q92688,P55786,Q99653,Q12955,Q9Y371,Q9P275,Q13614,Q86YS7 11 +Regulation of rna splicing 0.1847223338038729 0.0615871821509552 0.9508915847266944 1.0 1.0 89 Q14011,Q16629,P52597,Q8IY67,Q15427,P31942,P98179 7 +Cytosolic calcium ion transport 0.1851433612699526 0.0615179971736847 0.9509466818790866 1.0 1.0 24 P28161,Q07812,P20020,P55061,P78417 5 +Regulation of extrinsic apoptotic signaling pathway 0.1733048164274443 0.0599942547888281 0.9521602104640616 1.0 1.0 27 P09601 1 +Mitochondrial translational elongation 0.2704545454545539 0.0596053847560827 0.9524699295813844 1.0 1.0 5 Q96RP9,P43897,Q9H9J2,Q969S9 4 +Response to virus 0.1888364347732432 0.0589416719337296 0.9529985663260598 1.0 1.0 73 Q8IZ81,Q92538,Q13794,O95801,Q9NUD5,P35269,Q13217,Q07812,Q96J02,O14802,P14373,Q7Z7L1,Q9Y679,O43657 14 +Positive regulation of erk1 and erk2 cascade 0.2136196176430118 0.0588781537410133 0.953049158647906 1.0 1.0 13 Q13641,Q02952,P04899,P17252,P46109 5 +Establishment of cell polarity 0.162892581684697 0.0586321851419103 0.953245074735245 1.0 1.0 33 Q4VCS5,P61586,Q96N67 3 +Glutathione metabolic process 0.1918995582155041 0.0581601648864199 0.9536210507986906 1.0 1.0 20 O75874,Q8TB36,P78417,P28161 4 +Exocytosis 0.1878997161786845 0.057727212811374 0.9539659171466388 1.0 1.0 70 O15126,Q5JRA6,P51809,Q13277,O43760,Q6IQ22,O00471,Q9BRK5,P09601 9 +Regulation of platelet activation 0.2668696608057073 0.0576124676463767 0.9540573184240602 1.0 1.0 5 P07948,P17252,P80404 3 +Glial cell apoptotic process 0.2653190680978294 0.0566046650627716 0.9548601183228498 1.0 1.0 4 P17252,Q00535 2 +Hematopoietic stem cell differentiation 0.2595114271210983 0.0565563827282123 0.9548985804373964 1.0 1.0 7 P19525,Q96J02 2 +Dna dealkylation 0.2569850552306694 0.0553225874745825 0.9558814675176271 1.0 1.0 7 Q93008,P29372,Q9C0B1,Q8N3C0,Q93009,P27695 6 +De novo protein folding 0.1850629811778467 0.0547405151415723 0.9563451913197716 1.0 1.0 18 P54652,O14976,Q9NYU2 3 +Gastrulation 0.1548561031836969 0.0532779338903385 0.9575104614310264 1.0 1.0 26 Q6PD62,Q9NPQ8,Q99496,Q16881,Q4VCS5,Q9HCM4,P07942,P17252 8 +Cellular response to ionizing radiation 0.1827356151013994 0.0531325999571506 0.9576262571190894 1.0 1.0 19 P61254,P62993,P50570,Q9H1E3,P38398,Q96B01,O75844,Q99728,O60341 9 +Mirna metabolic process 0.2560538340982394 0.0526951151193399 0.9579748311901126 1.0 1.0 6 Q92945,O95453 2 +Regulation of mrna splicing via spliceosome 0.1815464253049669 0.0524583401440088 0.9581634893515516 1.0 1.0 66 Q14011,Q16629,Q8IY67,Q15427,P98179 5 +Gpi anchor metabolic process 0.2446035254687762 0.0523530909943869 0.958247350787127 1.0 1.0 8 O60762,Q969N2 2 +Regulation of platelet aggregation 0.2558403733060987 0.051979619558249 0.9585449326935178 1.0 1.0 4 P17252,P80404 2 +P body assembly 0.2475633528265108 0.0512486898350668 0.959127353913648 1.0 1.0 7 P26196,Q9HBH5,Q96F86,Q14204,P62310,A5YKK6 6 +Vesicle localization 0.1664719808763576 0.0508853365918806 0.9594168900767002 1.0 1.0 55 Q96A57,O00203,O95295,Q13561,Q00535,Q92538,P43034,P50570,Q9Y2T2,Q9H267,O00161,Q15907,O60763,O94832,P49755,Q13492,Q9HAS0,P62820,Q9UM54 19 +Terpenoid metabolic process 0.1770267684119941 0.0506470624592562 0.9596067605025072 1.0 1.0 19 Q9BY49,Q9Y394,P48449,P14324,Q9HB40 5 +Nucleobase biosynthetic process 0.1849954939324127 0.0503208677969327 0.9598666947369104 1.0 1.0 14 P17812 1 +Regulation of stem cell population maintenance 0.2509740259740353 0.0502388134550893 0.9599320819256908 1.0 1.0 5 Q5T200,Q15717,Q9Y6J9,A5YKK6 4 +Formation of primary germ layer 0.1753879472640915 0.0498291634167958 0.9602585264977914 1.0 1.0 16 Q6PD62,Q16881,P17252,Q9HCM4,P07942 5 +Signal transduction in absence of ligand 0.1788273615635243 0.0496256114455021 0.9604207367908256 1.0 1.0 15 P35221,P30153,P0DMV9,P30154,P49327,Q13546,Q07812,Q86WB0,Q16611,Q07820,O95817,P06756,O43464,P62136 14 +Isoprenoid biosynthetic process 0.2461302685168296 0.0488464888690524 0.961041633608072 1.0 1.0 6 P48449 1 +Negative regulation of protein acetylation 0.2404673713814629 0.0486855765154659 0.9611698705180504 1.0 1.0 7 Q9BX68 1 +Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.2456947561472096 0.0482693144475284 0.9615016095600302 1.0 1.0 5 Q9Y5S9,Q99729 2 +Mitotic spindle organization 0.1578405501654213 0.0475990078155122 0.962035822783522 1.0 1.0 55 Q96DB5,P14635,Q8N3U4,P61586 4 +Mitophagy 0.1791361711268202 0.0465129911182911 0.9629013798785548 1.0 1.0 13 P50851,P12235,A6NDU8 3 +Negative regulation of peptide secretion 0.2383116883116954 0.0458687789143075 0.963414838791429 1.0 1.0 5 Q8N183,Q8N5M9,Q16836,P17858 4 +Histone threonine phosphorylation 0.2360311166872341 0.0457011883753713 0.9635484166141888 1.0 1.0 6 O14757 1 +Small rna loading onto risc 0.2370129870129917 0.0454864355653367 0.9637195865592104 1.0 1.0 5 O94992,P55265,Q5KU26,Q08211 4 +Positive regulation of map kinase activity 0.2185833026085507 0.0430444967601889 0.9656660634186218 1.0 1.0 7 P30040,P23396,P41240 3 +Regulation of dna duplex unwinding 0.2294125640353449 0.042968396678459 0.9657267263732284 1.0 1.0 4 P49736 1 +Microtubule cytoskeleton organization involved in mitosis 0.1420217035241237 0.0416664371252127 0.966764610007943 1.0 1.0 60 Q96DB5,P14635,Q8N3U4,P61586 4 +Clathrin coat assembly 0.2046898926939684 0.0408500415326249 0.9674154452532692 1.0 1.0 7 P63010 1 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d0e31582052a0ca3d9d169174d3a505bd9286e60 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activation of store operated calcium channel activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Acylglycerol transport", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine catabolic process", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp metabolic process", "Amp salvage", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Arterial endothelial cell differentiation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Bile acid signaling pathway", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into cytosol", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in cardiac muscle cell fate commitment", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac cell fate commitment", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell fate commitment", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell myoblast differentiation", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine secretion", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide 1 phosphate transport", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Choline transport", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Commissural neuron axon guidance", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion import", "Copper ion transmembrane transport", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid receptor signaling pathway", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial skeletal system development", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytolysis by host of symbiont cells", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine secretion", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal aorta development", "Dorsal aorta morphogenesis", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Elastic fiber assembly", "Elastin metabolic process", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardial cushion development", "Endocardial cushion formation", "Endocardial cushion morphogenesis", "Endocardium development", "Endocardium morphogenesis", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil mediated immunity", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial to mesenchymal transition involved in endocardial cushion formation", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of left right asymmetry", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat pad development", "Fat soluble vitamin biosynthetic process", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated inhibitory signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Heat generation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "Hexose phosphate transport", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k119 monoubiquitination", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus development", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune effector process", "Immune response", "Immune response inhibiting cell surface receptor signaling pathway", "Immune response inhibiting signal transduction", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Inhibitory postsynaptic potential", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell fate commitment", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Iodide transport", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteinizing hormone secretion", "Luteolysis", "Lymph vessel development", "Lymphatic endothelial cell differentiation", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage differentiation", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Mast cell proliferation", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Melanosome assembly", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane fusion involved in viral entry into host cell", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Menaquinone metabolic process", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell fate commitment", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myoblast proliferation", "Myofibroblast differentiation", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immune response to tumor cell", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of astrocyte activation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of camp mediated signaling", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of catecholamine secretion", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular amine metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular response to vascular endothelial growth factor stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of ceramide biosynthetic process", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of dopamine secretion", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of g0 to g1 transition", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of histone acetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein metabolic process", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage activation", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage derived foam cell differentiation", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microglial cell activation", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuroinflammatory response", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl cysteine s nitrosylation", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sphingolipid biosynthetic process", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell differentiation in thymus", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor 2 signaling pathway", "Negative regulation of toll like receptor 4 signaling pathway", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nitrogen utilization", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Norepinephrine metabolic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation cycle", "Ovulation cycle process", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parathyroid gland development", "Paraxial mesoderm development", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification process", "Penetration of zona pellucida", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl l cysteine s palmitoylation", "Peptidyl lysine acetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericardium development", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine acyl chain remodeling", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyamine transmembrane transport", "Polyamine transport", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic process involved in development", "Positive regulation of apoptotic process involved in morphogenesis", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of b cell receptor signaling pathway", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell proliferation involved in heart morphogenesis", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of complement activation", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental pigmentation", "Positive regulation of developmental process", "Positive regulation of digestive system process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of enamel mineralization", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of heat generation", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of inhibitory postsynaptic potential", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic nuclear division", "Positive regulation of melanocyte differentiation", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myoblast proliferation", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immune response to tumor cell", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of store operated calcium channel activity", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tooth mineralization", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of uterine smooth muscle contraction", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor receptor signaling pathway", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein palmitoylation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adiponectin secretion", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte activation", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid secretion", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of development heterochronic", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of enamel mineralization", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate secretion", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of heat generation", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intestinal lipid absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage derived foam cell differentiation", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic nuclear division", "Regulation of melanocyte differentiation", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myoblast proliferation", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immune response to tumor cell", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pattern recognition receptor signaling pathway", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl cysteine s nitrosylation", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigment cell differentiation", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic cytosolic calcium ion concentration", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rab protein signal transduction", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle cell proliferation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of store operated calcium entry", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell apoptotic process", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 2 signaling pathway", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription from rna polymerase ii promoter involved in heart development", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell proliferation", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wnt signaling pathway involved in heart development", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to herbicide", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lithium ion", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cell programmed cell death", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Sebaceous gland development", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary heart field specification", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of bitter taste", "Sensory perception of chemical stimulus", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory perception of sweet taste", "Sensory perception of taste", "Sensory system development", "Septum primum development", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermidine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Store operated calcium entry", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Tolerance induction to self antigen", "Toll like receptor 2 signaling pathway", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by trans synaptic complex", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription factor catabolic process", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type b pancreatic cell proliferation", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Udp n acetylglucosamine transmembrane transport", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urea cycle", "Urea metabolic process", "Urinary bladder smooth muscle contraction", "Urinary tract smooth muscle contraction", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C2CD5", "C3orf58", "C5orf51", "CAAP1", "CAB39", "CACYBP", "CAD", "CALR", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPI", "CENPP", "CENPQ", "CENPU", "CENPV", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COG2", "COG5", "COG6", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLK", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAM162A", "FAM192A", "FAM207A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMC1", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "M6PR", "MACF1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS27", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NEPRO", "NES", "NFATC2IP", "NFS1", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "ROMO1", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RSRC1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35A4", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPOP", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM29", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF3", "TM9SF4", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM201", "TMEM214", "TMEM230", "TMEM33", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBIAD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "UROD", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YIF1A", "YIF1B", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZCCHC17", "ZCCHC3", "ZCCHC8", "ZDHHC20", "ZEB2", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF148", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["AARS", "AARS2", "AASDHPPT", "AATF", "ABAT", "ABCB8", "ABCE1", "ACAA2", "ACADM", "ACP6", "ACSL1", "ACSL6", "ACTL6A", "ACTR3", "ADAR", "ADD1", "ADD3", "ADNP", "ADPGK", "ADSS", "AFDN", "AGPAT1", "AHCYL1", "AIFM1", "AIMP2", "AKAP1", "AKAP12", "AKAP8", "AKT2", "ALDH1B1", "ALDH6A1", "ALDH7A1", "ALG1", "ALG13", "ALG2", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC5", "ANAPC7", "ANK3", "ANP32B", "ANXA4", "AP2A1", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEX1", "APOO", "APRT", "ARF4", "ARF6", "ARFIP1", "ARG2", "ARHGEF2", "ARID2", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMC1", "ARMCX3", "ARPC3", "ASCC3", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATP13A1", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5J2", "ATP5L", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP7B", "ATRIP", "AUP1", "AURKB", "BAG2", "BAG3", "BAG4", "BAG6", "BAIAP2", "BAK1", "BARD1", "BAX", "BCAP29", "BCAP31", "BCAT2", "BCCIP", "BCKDHB", "BCLAF1", "BCOR", "BICD2", "BRCA1", "BRD2", "BRD3", "BUB1B", "BUB3", "BUD23", "BYSL", "BZW2", "C17orf75", "C2CD5", "C3orf58", "C5orf51", "CAB39", "CAD", "CALR", "CAMK2G", "CAND2", "CARM1", "CBX1", "CCDC134", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD47", "CDC23", "CDC34", "CDC37", "CDCA5", "CDCA8", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2A", "CECR2", "CENPC", "CENPI", "CENPP", "CERS2", "CFL2", "CHCHD3", "CHD8", "CHEK1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CIRBP", "CKAP2", "CKAP5", "CLN5", "CLPB", "CLPP", "CLPTM1", "CLSPN", "CLTC", "CLUH", "CMTR1", "CNNM3", "CNOT1", "CNOT9", "COA1", "COG2", "COG5", "COG7", "COL4A3BP", "COLEC12", "COPG1", "COPS2", "COPS4", "CORO1C", "COX4I1", "CPT1A", "CRKL", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2B", "CTBP2", "CTNNA1", "CTNNB1", "CTPS1", "CTR9", "CUL1", "CYB5B", "CYB5D2", "CYB5R1", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DDRGK1", "DDX3X", "DDX6", "DENR", "DERL1", "DHCR24", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX36", "DHX8", "DHX9", "DIEXF", "DIP2B", "DKC1", "DNAAF2", "DNAJA1", "DNAJA2", "DNAJC10", "DNAJC3", "DNAJC7", "DNM1L", "DNM2", "DNPH1", "DOCK7", "DPM1", "DRG1", "DRG2", "DST", "DSTN", "DUS2", "DUSP9", "DYNC1H1", "DYNC1LI1", "EARS2", "EDC3", "EDRF1", "EEF1A2", "EFHD1", "EFL1", "EHMT1", "EHMT2", "EI24", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3D", "EIF3E", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4G1", "EIF5", "EIF5A", "EIF6", "ELAVL1", "ELL", "ELMOD2", "ELOC", "ELP1", "ELP3", "EMC3", "EMC7", "EMD", "EMG1", "ENAH", "EPB41", "EPB41L3", "EPB41L5", "EPDR1", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC6L", "ERGIC3", "ERMP1", "ERO1A", "ERP29", "ETF1", "EXO1", "EXOC1", "EXOC2", "EXOC5", "EXOC8", "EXOSC2", "EXOSC3", "EXOSC7", "EXOSC8", "EZR", "FAM162A", "FAM3C", "FAM49B", "FAM98A", 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sha256:4d8caadccaedfab19e9caa2a91fc6ced6adb6f8b4661a994cbdfe13d1399f604 +size 163847 diff --git a/msigdb_gocc/df_merge.tsv b/msigdb_gocc/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6cf1e258c77fc7cf9ee4370a0d39fce24e8588cb --- /dev/null +++ b/msigdb_gocc/df_merge.tsv @@ -0,0 +1,10 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Golgi membrane 50 136 2.707015267251262 0.0067891135116948 41.28398058252427 131.19174757281553 1.6327747521284677 0.3511039607499193 15.277988344159814 17.44963987873233 1.926180921267262 0.4033858283713009 0.3741084598076933 0.1463513896823768 0.2311788058225983 0.0080664651762468 0.0002241829846592 +Nuclear outer membrane endoplasmic reticulum membrane network 76 338 2.7008077174240923 0.0069171316097995 98.3519417475728 305.0218446601942 1.8626549185660248 0.4346737740195964 40.114822105305365 33.029069404441934 2.648813561163414 0.4525721946789457 0.1935446379545959 0.0027161550783321 0.0003061746784332 5.872353514573761e-06 4.698177664424842e-11 +Centriolar satellite 5 22 2.698438496012569 0.0069665609569984 6.631067961165049 24.325242718446603 0.3067804976927401 0.628129362137114 3.814866909745424 4.218089072853329 0.8031313068812725 0.3161655469328873 1.0 0.3498897642406863 0.0554265344441834 0.3709161428376983 0.2693368990210772 +Lipid droplet 4 32 2.532253063887018 0.0113332164572561 7.313106796116505 30.72087378640777 0.9597061621709796 0.3916106255858687 3.663189105886808 2.181620314734523 1.1934081113966928 0.3497541884861006 0.0021859430994627 0.0399341953324298 0.0261522178742545 0.0222803489742132 0.0416369881716056 +Endoplasmic reticulum 105 508 2.4410693651840862 0.01464384171895 139.71116504854368 475.50728155339806 1.972579372344309 0.4597126503683645 50.29410175615224 47.94654634280014 2.8130551221954065 0.458598772128197 0.134160844995466 0.0003871242900498 2.301757463273026e-05 3.199507022712815e-06 3.841631375968149e-11 +Intrinsic component of mitochondrial inner membrane 9 33 2.4074871008319167 0.016062729633278 13.946601941747574 31.446601941747577 1.7062420859184484 0.2149692261988765 6.992163651608136 3.3601842163433866 1.8185871159494191 0.3070405082296492 0.0526645480717147 0.0239365913088697 0.0125141686162342 0.0012901179564064 0.0001261001106924 +Golgi apparatus 66 297 2.3601144639623444 0.0182692970373408 79.29126213592232 307.80825242718447 1.0941692666231844 0.5225509759640199 24.90716006851961 39.34912971804267 1.7376904428153446 0.4394682295132952 0.6835069355535871 0.3585465520432483 0.3937707096677957 0.033894669574905 0.0128971091194719 +Organelle subcompartment 91 399 2.244704083467903 0.0247871357329589 115.97815533980582 370.4077669902912 1.8466078375892352 0.461199583276842 45.24176702976874 43.040100266333 2.697642340677977 0.4541841641473397 0.2835815027143931 0.0158356300411809 0.0009416782174521 6.44118488181389e-07 2.034138121189307e-11 +Replisome 1 10 2.076338704651179 0.0378626359828588 4.793689320388349 11.029126213592232 -0.3259251181443409 0.5340916631176766 2.8014661523044153 1.379153466819775 0.8950749159226318 0.3145547547877791 1.0 0.0697581245313758 0.1362380906066266 0.0506052248933858 0.1651798307910198 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..cb0add5ca169ccee7746b55dc3bb31d57913cf49 --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 893, + "title": "Average number of proteins per term", + "value": 28.251959686450167 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e1a43cd9e488ff3e0e65a60689defd91ac56c1cf --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..145f0b551cdf52cd55e52625b560879949569c7b --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,288 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Microtubule organizing center attachment site 0.8936101200129734 3.0262514696038325 0.0024760628092064 0.8907226416643603 0.0302893710770046 2 O94901 1 +Protein phosphatase 4 complex 0.8676613687966198 2.909965359809554 0.0036146881678167 0.9605911388844804 0.0398508214056833 2 Q8TF05 1 +Triglyceride rich plasma lipoprotein particle 0.8608498216023325 2.879167810122617 0.0039872610852245 0.9717804885246802 0.0425258931116861 2 Q9BUR5 1 +Cis golgi network membrane 0.8530651962374259 2.843830442943812 0.0044574761693856 0.9814896310706728 0.0452332524916064 2 Q9NPR9 1 +Golgi membrane 0.3969049839527896 2.707015267251262 0.0067891135116948 0.9977194806930532 0.0592489422342819 136 Q9H3P7,Q8NDZ4,Q6ZRP7,Q15392,Q9UHD1,P52292,P49257,Q9NRW7,Q9Y371,Q5BJH7,O43752,O95295,Q6IQ22,Q10713,Q9Y3B3,Q92538,P50570,Q16799,Q9UM00,O14653,Q9BUR5,Q9HC07,O75396,O00400,P60520,Q8IZA0,O60476,Q12907,P26572,Q9Y282,P04439,P98194,Q14746,P40616,Q8TB61,P24390,P83436,O43731,P35670,Q8N2H4,P42345,Q9UP83,O95249,Q7LGA3,P62820,Q16706,Q9Y3E0,Q99653,Q7L5N7,Q9Y5Z9 50 +Nuclear outer membrane endoplasmic reticulum membrane network 0.3167790907303862 2.7008077174240923 0.0069171316097995 0.9979674438964886 0.0592489422342819 338 Q99720,Q9NZ01,Q15392,P61619,Q9HD20,P51809,Q6NUQ1,Q5JRA6,Q5BJH7,Q9NP73,P56937,Q96HY6,O60762,Q969V3,Q8IY17,Q9NP72,Q5BJF2,Q9Y3B3,Q9P0I2,Q9BRR6,P67812,Q16799,Q9UM00,O14653,Q96RL7,P38435,Q9BUR5,Q96AA3,Q9UBV2,Q9UHQ4,Q8N0U8,Q8TDW0,O14681,O75396,O00400,Q53GQ0,Q9UKU0,P09601,Q7Z2K6,P26885,P61586,O75845,Q9BRK0,P30519,O15269,Q9NRR5,Q9Y282,Q92575,Q9NZ08,Q12907,P51571,Q8WXH0,Q13724,Q8TB61,Q13586,Q07812,Q9NQC3,O43865,P24390,A1L0T0,Q9BZF3,Q9Y679,Q03518,Q9Y5P4,Q14739,P33121,Q9C0E8,P10620,P61009,Q13555,O43852,Q9UHQ9,Q7L5N7,O60725,Q9Y5Z9,Q9NPA0 76 +Centriolar satellite 0.6520850779378834 2.698438496012569 0.0069665609569984 0.9980558104618718 0.0592489422342819 22 Q14145,Q86YS7,P41440,Q86UY6,Q03518 5 +Neurofibrillary tangle 0.8066818034382044 2.6301375156077103 0.008535033570177 0.9995260919965068 0.0699246328272302 2 P07197 1 +Lipid droplet 0.5643807884446798 2.532253063887018 0.0113332164572561 0.999962016115326 0.0850467419859642 32 Q9H6V9,Q99720,Q96RL7,O43760 4 +Endoplasmic reticulum 0.3126644607678039 2.4410693651840862 0.01464384171895 0.9999980999762852 0.1005919281155569 508 Q9H6V9,Q99720,Q15392,Q5BJH7,Q9UQB8,Q969V3,Q8IY17,Q5BJF2,Q9P0I2,Q16799,Q9H6E4,O14653,Q32P28,Q9NWM8,Q9UBV2,Q9UHQ4,Q9UMX5,Q53GQ0,P09601,P26885,Q9BRK0,O60476,Q14257,Q92575,P51571,Q8NBJ7,Q03518,P33121,Q9C0E8,Q9C0I1,O43852,Q9BRK5,Q9Y5Z9,P61619,O95302,P80303,Q96HY6,Q9Y3B3,Q96AY3,Q9BRR6,Q96RL7,Q12955,P38435,Q8N0U8,Q8TDW0,O14681,P30519,Q9Y282,Q13586,P24390,A1L0T0,Q9Y679,O95456,Q14739,Q9Y3E0,Q9UHQ9,O60725,Q9NPA0,Q9HD20,P51809,Q6NUQ1,P56937,Q9NYU2,Q9UM00,Q9BUR5,Q96AA3,Q8TED1,P13674,O75396,Q9UKU0,Q7Z2K6,P61586,O75845,O15269,Q9H2J4,Q9NZ08,Q9NUQ7,Q8WXH0,Q13724,Q9NQC3,Q9BZF3,Q14145,Q8IXB1,P10620,P61009,Q13555,Q9Y5P4,Q99653,Q7L5N7,Q9NZ01,Q5JRA6,Q15293,Q9NP73,O60762,Q9NP72,P67812,O00400,Q9NRR5,Q12907,O94832,P98194,Q8TB61,Q13217,Q07812,O43865 105 +Neurofilament 0.8677019412573689 2.426634357507192 0.0152396062913218 0.999998892861512 0.1028354799800602 3 P07196 1 +Intrinsic component of mitochondrial inner membrane 0.5437875910733935 2.4074871008319167 0.016062729633278 0.9999994753152838 0.1070449071829648 33 Q6P4A7,Q9H9P8,Q13505,O43819,Q9BUR5,Q15070,O60830,Q9H3K2,Q9GZY4 9 +Golgi apparatus 0.2955997301015816 2.3601144639623444 0.0182692970373408 0.9999999293374164 0.1168967728041278 297 Q9H3P7,Q8NDZ4,Q15392,P51809,O43823,Q9NRW7,Q9Y371,Q5BJH7,O43752,Q9UQB8,P80303,Q6IQ22,Q9ULU4,Q10713,O14976,Q9NP72,Q9UI14,Q9Y3B3,O15126,Q16799,Q9UM00,O14653,Q12955,Q96RL7,Q9BUR5,Q92520,O95782,Q9NPR9,Q9BZG1,Q9HC07,Q9GZM5,O14681,O75396,O00400,Q96A49,Q8IZA0,Q93050,O60476,Q12907,Q6P6C2,Q9Y282,P26572,P98194,Q14746,P40616,Q8TB61,Q9P260,P24390,P83436,O95456,Q96PU5,Q8N2H4,P42345,P20645,Q9UP83,Q99653,O95249,Q9HAS0,Q7LGA3,Q16706,Q9Y3E0,O43852,Q9Y5P4,Q9BRK5,Q7L5N7,Q9Y5Z9 66 +Signal peptidase complex 0.8279520483387203 2.2570657330536585 0.0240039676899201 0.9999999996223315 0.1410233101782811 3 P61009 1 +Organelle subcompartment 0.3083220180894006 2.244704083467903 0.0247871357329589 0.9999999998155904 0.1437331961657946 399 Q99720,Q15392,Q5BJH7,Q969V3,Q8IY17,Q5BJF2,Q9P0I2,Q16799,O14653,Q9UBV2,Q9UHQ4,Q9HC07,Q53GQ0,P09601,P26885,Q9BRK0,Q92575,P51571,Q9P260,Q03518,Q8N2H4,P33121,Q9C0E8,Q9UP83,O95249,O43852,Q9Y5Z9,P61619,O43752,Q96HY6,Q9Y3B3,Q9BRR6,Q96RL7,P38435,Q9NPR9,Q8N0U8,Q8TDW0,O14681,P30519,Q9Y282,Q14746,P40616,Q13586,P24390,A1L0T0,Q9Y679,P83436,Q14739,Q9UHQ9,O60725,Q9NPA0,Q9HD20,P51809,Q6NUQ1,P56937,Q9UM00,Q9BUR5,Q96AA3,O75396,Q9UKU0,Q7Z2K6,P61586,O75845,O15269,Q9NZ08,Q8WXH0,Q13724,Q9NQC3,Q9BZF3,P10620,P61009,Q13555,Q16706,Q9Y5P4,Q7L5N7,Q9NZ01,Q5JRA6,Q9NP73,Q10713,O60762,Q9NP72,O15126,P67812,Q9BZG1,O00400,Q9NRR5,Q12907,P98194,Q8TB61,Q07812,O43865 91 +Endoplasmic reticulum tubular network membrane 0.8026359606105721 2.14745265116294 0.0317572628522562 0.9999999999996952 0.1668190336886164 3 Q9C0E8 1 +Ribose phosphate diphosphokinase complex 0.7012650016217927 2.124110925876464 0.0336608691073117 0.9999999999999476 0.1734407096543742 2 Q14558 1 +Chromatoid body 0.7009406422315878 2.1225105736914034 0.0337948857178285 0.9999999999999536 0.1734407096543742 2 Q08J23 1 +Replisome 0.7626866613698492 2.076338704651179 0.0378626359828588 0.9999999999999988 0.1868029499043811 10 P25205 1 +Mhc protein complex 0.6899124229646387 2.0679455036017824 0.0386451478779421 0.9999999999999994 0.1885798746174991 2 P04439 1 +Mhc class i protein complex 0.6899124229646387 2.0679455036017824 0.0386451478779421 0.9999999999999994 0.1885798746174991 2 P04439 1 +Axolemma 0.7757440974578305 2.0296739655186644 0.0423896909429852 1.0 0.1992861124984822 3 Q9Y2J2 1 +Cortical endoplasmic reticulum 0.7689811810512734 1.9998425770471464 0.0455172654073277 1.0 0.2106057927914178 3 Q13586,P50402 2 +Tor complex 0.6720726565033961 1.9790594267025992 0.0478093158685248 1.0 0.214541301862275 2 P42345 1 +Torc1 complex 0.6720726565033961 1.9790594267025992 0.0478093158685248 1.0 0.214541301862275 2 P42345 1 +Intrinsic component of mitochondrial membrane 0.4224493788217502 1.9186284002125384 0.0550313787319751 1.0 0.2385583553769603 51 P57105,Q13505,Q9UH62,Q6P4A7,Q9H9P8,Q9BUR5,Q9GZY4,Q8TB36,Q9UG56,O60830,Q9H3K2,P12235,Q96NB2,Q8IXI1,P50416,O43819,Q9NX63,Q15070,O96008 19 +Proton transporting atp synthase complex coupling factor f o 0.7888134980347689 1.811996422238446 0.0699867493239145 1.0 0.2815232754335843 7 P00846,O75964 2 +Proton transporting atp synthase complex 0.6565202058179249 1.804454203237991 0.0711601323736768 1.0 0.2849596332273246 12 P00846,P56134,O75964 3 +Cytoplasmic stress granule 0.4396488992200216 1.7704131266194827 0.0766583446190329 1.0 0.2990334565682218 41 O75534,Q14011,Q01085,Q71RC2,Q9NR56,Q9UN86,P06730,P05198,P61978,P11940,O00571,P26196,Q13310,P67809,Q7Z417,Q9HCE1,Q6Y7W6,Q92499,O95793,Q14258,Q92879 21 +Main axon 0.805622081297239 1.768183585633823 0.0770302173814858 1.0 0.2990334565682218 4 Q9Y2J2,Q12955 2 +Golgi medial cisterna 0.8051432023976985 1.766252126786749 0.0773535593138401 1.0 0.2990334565682218 4 Q16706,O95249 2 +Meiotic spindle 0.7144421448616678 1.7563663002395602 0.0790258831942054 1.0 0.2992462677851278 3 P54652 1 +Carboxy terminal domain protein kinase complex 0.7143957585967504 1.75615716940545 0.0790615757114987 1.0 0.2992462677851278 3 P50750 1 +Outer kinetochore 0.8019419254598787 1.7533334593773928 0.0795447853970194 1.0 0.2992462677851278 4 P14635,O60566 2 +Neuron to neuron synapse 0.4022683678276477 1.748268969407137 0.0804174638145074 1.0 0.2992462677851278 53 Q99720,Q9UEY8,P51114,P50570,O43815,Q9NQC3,Q9UQB8,P35611,Q13614,P51991,P62263 11 +Golgi transport complex 0.7957372463886168 1.740497999449906 0.0817716110468376 1.0 0.3005085714090734 5 Q9UP83,Q14746 2 +Outer membrane 0.3809371590670991 1.7404882069267795 0.0817733290620434 1.0 0.3005085714090734 90 Q99720,Q13505,Q9UH62,Q9Y371,Q8WWI5,Q9H974,Q6P1Q0,Q96RL7,Q9BUR5,O43169,Q9UKU0,P09601,Q8WXH0,Q07812,Q9NVT9,Q9BUK6,Q8WY22,Q9BX68,P42345,P33121,Q13794,P50416,P10620,O60313,O96008 25 +Protein kinase complex 0.5146813257318169 1.715762666955188 0.0862054897203714 1.0 0.3061996227741958 21 P78527,P49736,P14635,Q96T76,Q13131,Q9P287,P54619,P24941,P50750,P11802,Q00535 11 +Rough endoplasmic reticulum 0.4635408388112688 1.7146579559006905 0.0864079562587876 1.0 0.3061996227741958 32 P51571,Q9UQB8,Q5BJF2 3 +Proteasome core complex beta subunit complex 0.7641269892033888 1.706566980465709 0.087902566836707 1.0 0.3098074302607858 7 P20618,P28070,P49721,P28074 4 +Mll1 2 complex 0.5563678549060481 1.705399623223059 0.0881199185736165 1.0 0.3098074302607858 16 Q03164,Q8IZL8,Q15291,Q9H4L4 4 +Endoplasmic reticulum protein containing complex 0.3876337541061409 1.699361746149285 0.0892510450354655 1.0 0.3115849250116644 64 Q9P0I2,Q8IXB1,Q9NPA0,P61619,Q6NUQ1,P51571,P61009,Q9UBV2,P13674,Q53GQ0,Q9Y679,Q03518,O15269 13 +Mitotic cohesin complex 0.6110930911449834 1.6699206625936966 0.0949350616263289 1.0 0.3184518700740092 2 O60216 1 +Lamellipodium 0.3980836024179839 1.6618454541402092 0.0965437657646965 1.0 0.3193095660291631 51 P50570,P51809,Q8WXH0,Q13277,O60749,O15145,Q9UQB8,Q13576,Q4VCS5,P41440,P61586,Q7L576,Q00535,Q13418 14 +Magnesium dependent protein serine threonine phosphatase complex 0.7490882275213159 1.64199344024635 0.1005913635398285 1.0 0.3266475914220615 7 Q9NY27,Q8TF05 2 +Myosin filament 0.6046059033408999 1.6366088501117042 0.1017122252333955 1.0 0.3290906417877615 2 P35579 1 +Nuclear replication fork 0.5447590229313704 1.6334992869085934 0.1023640305767583 1.0 0.3300038964081054 16 P25205,P49005,Q9UNS1 3 +Filopodium 0.4758492740822325 1.627858052680789 0.1035549876671733 1.0 0.3314501935010242 26 P46939,P51114,Q9Y4F1,Q8WXH0,O95782,Q9UQB8,Q13576,Q7L576 8 +Transferase complex transferring phosphorus containing groups 0.3752085648834736 1.621338043424455 0.1049451603028748 1.0 0.3329137411191707 74 P17858,P49736,P25205,Q99570,Q00535,Q6PD62,P62487,P50750,Q9HBM6,P11802,P23193,P14635,O00411,O15160,O14802,Q96T76,Q9NRG0,P49005,P35269,O15514,Q9NR33,P54619,Q14558,P24941,P19387 25 +Intrinsic component of organelle membrane 0.3296543775834448 1.6136218585251445 0.106609472625857 1.0 0.3364037422434289 152 Q9NZ01,P61619,O96008,Q13505,O43808,Q9UH62,Q5BJH7,O43752,O94901,Q9P0I2,Q6P4A7,Q9H9P8,O96011,Q16799,Q9UM00,Q9BUR5,Q9GZY4,Q9Y282,Q13586,Q9NQC3,O60830,Q9H3K2,Q9Y679,Q03518,Q14739,Q96NB2,Q8N2H4,Q9C0E8,P50416,O43819,Q15070,Q9Y5Z9,Q9NPA0 33 +Emc complex 0.7581308816588941 1.5985480473494922 0.1099210613187986 1.0 0.3385405226333257 6 Q9P0I2 1 +Escrt i complex 0.5968212779759938 1.596545028888062 0.1103671608042138 1.0 0.3385405226333257 2 Q9NZ09 1 +Intrinsic component of golgi membrane 0.5362481326045229 1.5806448195105582 0.1139592718257951 1.0 0.3454254324483403 16 Q8N2H4,Q9Y282,Q6ZRP7,P98194,Q8TB61,Q5BJH7,Q9Y5Z9 7 +Replication fork 0.4363032375107338 1.577911699529626 0.1145858968333757 1.0 0.3454254324483403 35 Q96T88,Q9UNS1,O75717,P49005,P25205,O14757,P49959,P41440 8 +Organelle inner membrane 0.2867851735423337 1.5778276221697838 0.1146052162308179 1.0 0.3454254324483403 256 Q9NPL8,Q99720,P13073,O43772,Q13505,P03886,Q70HW3,Q9BSK2,Q8TBP6,P00846,Q16718,O94901,O43676,Q6P4A7,Q9H9P8,P09669,Q9NUT2,Q9UDX5,Q9BUR5,P62072,P08574,Q96IX5,Q9GZY4,Q9BQT8,Q9NRX2,O95168,Q13423,O60830,Q9H3K2,O95831,P53701,Q86VD7,Q14739,Q9BYN8,O75964,Q5T9A4,O43819,Q96CU9,Q567V2,O96000,P56134,Q15070,Q9P0J0 43 +Endoplasmic reticulum golgi intermediate compartment 0.3954490303235861 1.5698135671066364 0.1164584903159364 1.0 0.3489846706447358 49 Q12907,P26572,Q9Y282,Q9UHD1,O14653,Q03519,Q5BJH7,P80303,P24390,Q9NYU2,O75396,Q99653,Q9Y3B3,Q03518 14 +Axon hillock 0.590334090171901 1.5630892255495883 0.11803160952971 1.0 0.3525158104014416 2 Q9ULW0 1 +Bcl 2 family protein complex 0.7521600194342104 1.551036025192569 0.1208930509033439 1.0 0.356116894889485 4 Q07812,Q13794 2 +Cyclin dependent protein kinase holoenzyme complex 0.6807967711141961 1.5490573877238796 0.1213679252424291 1.0 0.356116894889485 9 P49736,P14635,P24941,P50750,P11802 5 +Dna replication preinitiation complex 0.680474571191879 1.5475464290961818 0.1217315378229617 1.0 0.356116894889485 9 Q9BRX5,Q9UBD5,Q9BRT9,P25205 4 +Ccr4 not complex 0.5867661368796603 1.544663637269117 0.122427644715646 1.0 0.356116894889485 2 Q92600 1 +Ccr4 not core complex 0.5867661368796603 1.544663637269117 0.122427644715646 1.0 0.356116894889485 2 Q92600 1 +Endoplasmic reticulum golgi intermediate compartment membrane 0.4584988970995119 1.5264597232842751 0.126895413742953 1.0 0.3608840906766147 27 Q12907,P26572,Q9Y282,O14653,Q5BJH7,P24390,O75396,Q9Y3B3,Q03518 9 +Centrosome 0.3247601453764541 1.517516191884857 0.1291364085678918 1.0 0.3660914693686585 136 Q9Y5K8,Q13432,P25205,Q96CW5,Q86YS7,P41440,O75935,Q9NY27,P50570,P29966,A0AVF1,Q9UJW0,Q86UY6,Q00013,P28074,P14635,Q9H6D7,Q14145,Q13416,Q03518,Q9Y5K6,Q6DKK2,Q8IX90,Q5T4S7 24 +Gamma tubulin complex 0.6607511871726854 1.5124017900355395 0.1304316798257847 1.0 0.3685933230519803 3 Q96CW5 1 +Elongator holoenzyme complex 0.6586632057105739 1.5028497792495412 0.1328777859403536 1.0 0.3731442227821879 3 Q6IA86,O95163 2 +Gemini of coiled bodies 0.7303452297172268 1.471538907587501 0.141145433459378 1.0 0.3866345769301367 5 Q8TEQ6,Q16637,P57678 3 +Proton transporting two sector atpase complex 0.4675811273659088 1.464247579373159 0.1431263143583652 1.0 0.3903284650357647 23 P00846,Q9Y487,P56134,O75964 4 +Dna polymerase complex 0.5694167973713031 1.4633628221399833 0.143368126015376 1.0 0.3903284650357647 13 P49005,P25205 2 +Proteasome core complex 0.5310863759720206 1.457248272583134 0.1450478598853983 1.0 0.3932310022307587 15 P28070,P49721,P28074 3 +Clathrin coat of endocytic vesicle 0.7212203945663975 1.4337529039543104 0.1516427890959373 1.0 0.4015434224712383 5 O95782,Q96CW1,P63010 3 +Proton transporting two sector atpase complex proton transporting domain 0.6083564266196754 1.432558808337306 0.1519839605770196 1.0 0.4015434224712383 11 P00846,P56134,O75964 3 +Origin recognition complex 0.6972059779077415 1.4177240181540187 0.1562713549996717 1.0 0.4080418713880316 7 P49736,Q9Y619,P33993,Q9Y5N6,Q13416,Q9UBD5 6 +Inner mitochondrial membrane protein complex 0.357691466435891 1.4131188763395237 0.1576207739091297 1.0 0.4103654551045274 84 O43676,P13073,P09669,O75964,Q13505,P03886,Q9BUR5,O95168,P62072,Q96CU9,Q9P0J0,O96000,O60830,P00846,Q16718,P56134,Q96IX5 17 +Dynactin complex 0.7126276676183478 1.388981602399967 0.1648383445323671 1.0 0.4254353805416295 4 O75935 1 +Mitochondrial envelope 0.2681172755222267 1.3789650412012755 0.1679055327114942 1.0 0.4271784635651405 334 Q9NPL8,P13073,P11310,O43772,Q13505,P03886,Q70HW3,Q9Y619,Q9Y371,Q9BSK2,Q9UH62,Q8WWI5,Q10713,Q8TBP6,P52888,P00846,Q16718,Q02218,Q9H974,Q9BYT8,O43676,Q6P4A7,Q96AY3,Q9H9P8,P09669,Q9NUT2,Q9UDX5,Q96RL7,Q9BUR5,P62072,P08574,Q96IX5,Q9UKU0,P09601,Q9GZY4,Q9BQT8,Q9NRX2,O95168,Q9NVT9,Q13423,O60830,Q9H3K2,Q8WY22,O95831,Q9BUK6,Q86VD7,P53701,O15228,Q9BYN8,Q96NB2,O75964,P33121,Q5T9A4,Q13794,P50416,O43819,Q96CU9,P10620,Q567V2,O96000,P56134,Q15070,O60313,Q9P0J0,Q9Y5Z9,O96008 66 +Messenger ribonucleoprotein complex 0.707251903519953 1.3758436355561974 0.1688700486549863 1.0 0.4284117995707466 5 P51991,Q99729 2 +Brca1 a complex 0.629499878256017 1.3691171473072912 0.1709626590989605 1.0 0.4324919393070023 3 P38398 1 +Trans golgi network membrane 0.4268883824858064 1.344936587821128 0.1786457134613561 1.0 0.4456162629077962 29 Q8N2H4,Q14746,P40616,Q9UP83,O43752,Q9HC07 6 +Cell body membrane 0.6229720960415241 1.3391289959987345 0.1805286824159973 1.0 0.4482348124963201 3 P55011,P20020 2 +Mediator complex 0.506711069921787 1.310381312495622 0.1900668722590746 1.0 0.4573167935249007 15 Q71SY5,Q6P2C8,Q9Y2X0,Q9NYF8,P50750,P11802,O60244 7 +Extrinsic component of mitochondrial inner membrane 0.6164828033744421 1.3093103716197985 0.1904292377988967 1.0 0.4573167935249007 3 P49748,Q96BW9 2 +Sarcoplasm 0.467404503388706 1.3090837357872314 0.1905059878961512 1.0 0.4573167935249007 19 Q8WXH0,Q12955,Q13586,Q9C0I1,Q13555,O43852 6 +Neuron spine 0.4284819811929885 1.293864030326716 0.1957123908730844 1.0 0.4682361327961304 27 P51114,Q9Y4F1,Q9UQB8,Q13614,P61586 5 +Microtubule organizing center 0.3073442071845938 1.289708014375612 0.1971520559141601 1.0 0.4682361327961304 166 Q9Y5K8,Q14166,Q13432,Q15555,P25205,Q96CW5,Q86YS7,P41440,O75935,Q9NY27,P50570,P29966,P38398,A0AVF1,Q9UJW0,Q86UY6,O60763,P50402,Q00013,P28074,P14635,O60566,Q9H6D7,Q15691,Q14145,Q13416,O14757,Q03518,Q9Y5K6,Q6DKK2,Q8WWK9,Q8IX90,Q96T76,Q9Y6G9,P24941,P28070,Q5T4S7 37 +Extrinsic component of endoplasmic reticulum membrane 0.5364904313979794 1.283773289092642 0.1992212922029286 1.0 0.471895527684921 2 O14656 1 +Smn complex 0.6713481956113428 1.2269072282438611 0.219857461491834 1.0 0.5111017888458224 5 Q16637,P57678 2 +Nadh dehydrogenase complex 0.419462105231642 1.224292243227155 0.2208420020372834 1.0 0.5111017888458224 27 O43676,P03886,O95168,Q96CU9,O96000,Q9P0J0 6 +Ciliary transition zone 0.6663345094250448 1.2147971160733224 0.2244434810605049 1.0 0.5139180220180279 6 A6NIH7 1 +Npbaf complex 0.6085175340631117 1.2091797678339935 0.2265937888314559 1.0 0.5175147146457549 9 Q8WUB8 1 +Extrinsic component of synaptic membrane 0.6586664551795834 1.17438756769481 0.240239822669261 1.0 0.5412972568187309 5 P52292,Q13492,Q9Y4F1 3 +Endoplasmic reticulum tubular network 0.4952665289445429 1.1665220848027429 0.2434034247680951 1.0 0.5412972568187309 14 P50402,Q9C0E8,Q12797,Q13586,Q9NQC3,Q9NP72,Q9BRK0 7 +Mitochondrial crista 0.6556312885426842 1.1548357567275709 0.2481576914433647 1.0 0.5458246760072037 4 P18031,Q9BUB7,O60313 3 +Rna polymerase iii complex 0.6507627393703376 1.13489815099099 0.2564179947468381 1.0 0.5571632710215001 4 O15160,O14802,P62875 3 +Rough endoplasmic reticulum membrane 0.4887134217084142 1.1285814010196211 0.2590744602601238 1.0 0.5571632710215001 14 P51571,Q5BJF2 2 +Extrinsic component of postsynaptic membrane 0.6491755065691912 1.1284026713271835 0.2591499001422805 1.0 0.5571632710215001 4 P52292,Q9Y4F1 2 +Derlin 1 retrotranslocation complex 0.6469729089274109 1.1260625844611216 0.2601390297183761 1.0 0.5571632710215001 5 Q9UBV2,Q8TCT9,Q8WU17 3 +Cop9 signalosome 0.6103083221989323 1.1122386252313523 0.2660355646725942 1.0 0.5623391493355611 8 Q13098,P62993,Q9BT78 3 +Endoplasmic reticulum lumen 0.3393394664757557 1.1114581925241578 0.2663711760010552 1.0 0.5623391493355611 60 Q96AY3,Q14257,Q9NZ08,Q5JRA6,Q8IXB1,Q32P28,Q9NWM8,Q8TED1,P13674,Q9NYU2,O43852,Q8NBJ7 12 +Camp dependent protein kinase complex 0.5663765929853579 1.0796103774550814 0.2803157183279876 1.0 0.5821440382950999 3 P17252 1 +Filopodium membrane 0.6364571459985657 1.07645046046326 0.2817258452015032 1.0 0.5837150342574069 4 Q8WXH0 1 +Scf ubiquitin ligase complex 0.6169218833750643 1.070121670108276 0.2845645461433892 1.0 0.5880472985004646 7 Q96K76 1 +Synaptonemal structure 0.570657779505084 1.032396706151729 0.3018863143563259 1.0 0.611962309781913 9 P53350,P54652,P38398,Q9NQS7,O60216 5 +Cul3 ring ubiquitin ligase complex 0.6216681243389501 1.0289098045957077 0.3035220606485733 1.0 0.611962309781913 6 O43791 1 +Bleb 0.6173279561248143 0.998726246438653 0.3179273225919545 1.0 0.6337256675772666 4 Q9BRK5 1 +Clathrin adaptor complex 0.5821114843697422 0.986797377327824 0.3237419807158561 1.0 0.6396052849098662 8 O95782,Q96CW1,Q9Y2T2,P63010,O94973 5 +Mib complex 0.5351671840206699 0.9688723481428948 0.3326088835803156 1.0 0.6542284868661274 10 Q13505,Q9BUR5,Q5XKP0,Q9NX63 4 +Lumenal side of endoplasmic reticulum membrane 0.6057161416044132 0.9632446530488584 0.3354247612809549 1.0 0.6574817182264697 6 Q8TCT9,P27797,P04439,P10321,P51572 5 +Nuclear pore outer ring 0.5735343387609119 0.949006384011296 0.3426173651742885 1.0 0.6636817941445546 8 Q8NFH4,Q8NFH3,Q96EE3,Q8WUM0,Q12769 5 +Rna polymerase complex 0.3530065517706101 0.9389667239956736 0.3477478293294049 1.0 0.6693733093389198 39 Q6PD62,P62487,P35269,O00411,P25205,O15514,O15160,O14802,Q9HBM6,P19387 10 +Hrd1p ubiquitin ligase erad l complex 0.5995875199833818 0.9321544383997404 0.3512567177322392 1.0 0.6739576767075227 5 Q9UBV2 1 +Er ubiquitin ligase complex 0.5971918663028897 0.9283903102446648 0.353205143000135 1.0 0.6739576767075227 6 Q9UBV2 1 +Condensed nuclear chromosome 0.4005458307799132 0.9221320377082568 0.3564597075467857 1.0 0.6777079190324079 21 Q9UEY8,P53350,P54652,P38398,Q9NQS7,O60216,O14757,Q8N3U4,Q92878 9 +Rna polymerase ii core complex 0.5816719241208212 0.9199906057601092 0.3575776684223459 1.0 0.6777079190324079 7 P19387,P62487,O15514 3 +Zymogen granule 0.5959031824185258 0.9172691662580472 0.3590016104972955 1.0 0.6777079190324079 5 O15126,P08754,Q13277 3 +Lateral element 0.5955588136659985 0.9111321669828076 0.3622257395916159 1.0 0.67955375095654 4 Q9NQS7 1 +Mcrd mediated mrna stability complex 0.5897435897435934 0.8879314287868622 0.3745776376003615 1.0 0.6968704799523393 4 Q14103,O75534,P11940 3 +Cytoplasmic ubiquitin ligase complex 0.5387441463395926 0.8859788801007906 0.3756289080955599 1.0 0.6973734198115074 9 Q9UBV2 1 +Cytoplasmic exosome rnase complex 0.4973989628381033 0.8706139204731733 0.383964993109199 1.0 0.7069705955598242 11 Q13868,Q96B26,Q9NQT5 3 +Mhc class i peptide loading complex 0.5806077388250299 0.8558879920060148 0.3920597375750265 1.0 0.7159700320132898 5 Q03519,Q03518 2 +Golgi associated vesicle membrane 0.4066693106190261 0.8539848559817401 0.3931133804104119 1.0 0.7164290789928526 17 P53621,Q8NDZ4,O95782,Q9Y678,P24390,P42356,Q9Y3B3,O43731 8 +Endolysosome membrane 0.5627692967481936 0.8409180545764205 0.4003938431807909 1.0 0.721449609021189 7 O95782,Q96CW1,O94973,P63010 4 +Transport vesicle 0.3085893830269028 0.8391421613780173 0.4013895392934232 1.0 0.721449609021189 93 Q96A57,Q9UHD1,P51809,P49257,Q9NRW7,O43752,Q6IQ22,Q13614,Q9UI14,Q9Y3B3,Q9BT78,O15126,Q14141,O14653,O95782,Q9GZM5,O75396,Q15907,P04439,Q13277,O43760,P24390,Q13492,O43731,P20645,O95249,P62820,Q99653,O94979 29 +Vesicle coat 0.3619826075132846 0.8386034090891001 0.4016918969950196 1.0 0.721449609021189 29 P53621,Q8NDZ4,O95782,Q96CW1,Q9Y678,P63010,O95487,Q8NC96,O94973,Q9Y3B3,O94979 11 +Respirasome 0.3257097316459545 0.8293446856992148 0.4069093918830866 1.0 0.7225090622609684 47 O43676,P13073,P09669,P03886,O95168,Q96CU9,Q13423,O96000,Q16718,Q9P0J0 10 +Signal recognition particle 0.5719389412146711 0.8263771014560174 0.4085902088046267 1.0 0.7225090622609684 6 P09132,Q9UHB9,P37108,P49458,O76094 5 +Zymogen granule membrane 0.5739195130485963 0.8253206111868437 0.4091895931829785 1.0 0.7225090622609684 4 O15126,Q13277 2 +Intrinsic component of nuclear inner membrane 0.563274138879702 0.7918938404864492 0.4284225787904046 1.0 0.7437676976433225 6 Q14739 1 +Transport vesicle membrane 0.3289050381115561 0.787118467658542 0.4312125195313738 1.0 0.7437676976433225 43 P51809,P49257,O95295,O43752,Q9Y3B3,O15126,O95782,O14653,P20020,O75396,Q15907,O60763,P04439,O43760,P49755,P20339,Q9Y6Y8,P62820,O00429,O94979 20 +Sin3 complex 0.5631701417149231 0.7868754059989569 0.4313548059005883 1.0 0.7437676976433225 5 Q9UBU8 1 +Nuclear inner membrane 0.3879723781894462 0.7867380281781347 0.4314352378266977 1.0 0.7437676976433225 19 Q99720,Q14739 2 +Clathrin vesicle coat 0.4952777850765876 0.7805120379145399 0.4350895446953826 1.0 0.7476629483021402 10 Q8NC96,O95782,Q96CW1,P63010 4 +P body 0.3660227574639256 0.7721057766684515 0.4400517811254549 1.0 0.7528088899330101 24 P26196,P60900,P62487,Q9HCE1,Q92900,O75534,Q96C86,O15514,P62312,P25787,P06730 11 +Copi coated vesicle membrane 0.4585251944840534 0.7632335918885617 0.4453240985528901 1.0 0.7589206488697153 12 P24390,Q9Y3B3 2 +Myosin ii complex 0.555014605647521 0.7517170089597576 0.4522212594792936 1.0 0.7688819189045556 4 P14649,P35579,P35580 3 +Translation preinitiation complex 0.4214861151373152 0.7501791219750201 0.4531468313372127 1.0 0.7688819189045556 14 O15372,P60228,O15371,O75822,P05198 5 +Coated vesicle membrane 0.3061853359933382 0.7436947817706986 0.4570611470908092 1.0 0.7713159561410069 54 Q8NDZ4,P51809,P49257,Q8NC96,Q9Y3B3,O95782,O14653,O75396,P10321,P53621,O60763,P04439,P24390,P49755,P20339,O94973,O43731,Q9Y6Y8,P20645,Q96CW1,Q9Y678,P63010,O95487,O94979 24 +Haus complex 0.5526214386383466 0.7425075043225254 0.4577799067802168 1.0 0.7713159561410069 4 Q9H6D7 1 +Snare complex 0.3979625037320572 0.7346620927553298 0.462545312010691 1.0 0.7737433659022758 16 O43752,O14653,O95249,P51809 4 +Clathrin coat of coated pit 0.5027592078975412 0.7260595761498311 0.4678022489354818 1.0 0.779379493095868 9 Q00610,O95782,Q96CW1,Q13492,P63010,O94973 6 +Microtubule cytoskeleton 0.2326941686408159 0.723958311071917 0.4690913294146133 1.0 0.7800718010563309 297 Q9Y5K8,Q9UHD1,O75376,Q14166,Q13432,Q15555,P25205,Q9UQB8,Q96CW5,Q99570,Q86YS7,P41440,O75935,Q9NY27,Q14141,Q9UJX3,P50570,P29372,P29966,Q96SI9,P23396,A0AVF1,Q9BZK7,Q9UJW0,Q86UY6,Q9BRK0,Q96DB5,P83916,Q00013,P28074,P14635,Q13586,O60566,Q99426,Q9NQS7,Q9H6D7,Q9UJX4,Q96P70,Q14145,Q13416,O14757,Q08J23,Q8N3U4,Q03518,Q9Y5K6,Q6DKK2,Q8IX90,P54652,P52732,Q96T76,O95816,P50748,O60313,P24941,P28070,Q99653,Q96SB8,Q5T4S7,O95793 59 +Cullin ring ubiquitin ligase complex 0.3361914954515674 0.7156362159593923 0.474216005119922 1.0 0.7836248990253115 34 Q9UJX3,Q9H1A4,O43791,O60566,Q14145,Q16763,Q96K76 7 +Transcription repressor complex 0.3830840051616583 0.7119802244237281 0.4764770219230376 1.0 0.7836248990253115 17 O75376,Q13547,Q9BZK7,Q5TKA1 4 +Micos complex 0.5436402420692374 0.7111024115592285 0.4770207757064804 1.0 0.7836248990253115 5 Q9NX63,Q9BUR5 2 +Copi coated vesicle 0.4308755319097608 0.7091230524363866 0.4782481186660636 1.0 0.7836248990253115 13 P24390,Q9Y3B3 2 +Transcription factor tfiiic complex 0.5418506273209279 0.7042521296782783 0.4812757720962475 1.0 0.7857024944825393 5 Q9Y5Q8 1 +Rna polymerase iii transcription regulator complex 0.5418506273209279 0.7042521296782783 0.4812757720962475 1.0 0.7857024944825393 5 Q9Y5Q8 1 +Nucleotide activated protein kinase complex 0.5407215915930057 0.6999391353512993 0.4839653157077761 1.0 0.7886515089909564 5 Q13131,P54619 2 +Vesicle tethering complex 0.3658289613034405 0.6950979419016804 0.4869939244736392 1.0 0.7920758243318954 21 Q14746,Q9UP83,P83436 3 +Filopodium tip 0.5360129242175087 0.6820264875069909 0.495222202326965 1.0 0.8011475120977893 5 O95782 1 +Transferase complex 0.2602157760508888 0.6751907337764881 0.4995545930209997 1.0 0.8066948491279434 215 Q15291,Q9H7D7,P17858,Q03164,P49736,P25205,Q5T200,O60762,Q99570,Q8IZL8,Q02218,Q9H974,Q00535,Q6PD62,P62487,Q9UJX3,Q9H1A4,P38398,Q96ES7,Q6W2J9,Q9UBV2,Q9HCK8,P50750,Q53GQ0,Q9HBM6,Q15369,Q96K76,P11802,O15269,P80404,P14635,O60566,Q6P2C8,O00411,O15160,Q9UJX4,A1L0T0,Q96P70,Q14145,Q16763,Q9Y679,O14802,Q9Y2Z0,Q9UBU8,Q13616,O43791,Q96T76,P35269,P49005,Q9NRG0,Q9H4L4,O15514,Q14558,P54619,Q9NR33,P24941,Q9BXJ9,P19387,Q96SB8 59 +Sarcoplasmic reticulum membrane 0.4878391109975362 0.6620774715146751 0.5079215730342779 1.0 0.8169910140723103 9 Q8WXH0,Q13586 2 +Endocytic vesicle membrane 0.3154928076379736 0.6600813467042379 0.5092016283181562 1.0 0.8169910140723103 42 P51809,Q03519,Q9Y487,Q99570,P50570,O95782,Q5KU26,Q9BZG1,O75396,O00161,Q93050,Q15907,P04439,Q6WKZ4,Q03518,P20645,Q96CW1,Q8WTV0,Q13555,P63010 20 +Nuclear exosome rnase complex 0.4636333541061528 0.6379944124498407 0.5234773173442882 1.0 0.828839085795123 10 Q96B26,Q9NQT5 2 +Cd95 death inducing signaling complex 0.4080441128770636 0.6358396744204896 0.5248809252881286 1.0 0.8294787964200975 2 P49327 1 +Eukaryotic translation initiation factor 4f complex 0.5221352995897555 0.6331006038154982 0.5266679480069376 1.0 0.8294787964200975 6 P23588,P06730,Q04637,O43432 4 +Annulate lamellae 0.5194862531982664 0.6201882690319632 0.5351338438813129 1.0 0.8369080955972197 5 P63241,Q8TD16,O14980 3 +Axon 0.2806173743087277 0.6114037954939773 0.5409322905567797 1.0 0.8430236221068138 108 Q99720,P11310,Q9UH62,Q13614,Q9P265,Q13641,Q14141,Q9UBB6,Q12955,Q9Y2J2,Q96A49,P61586,O94832,Q13277,Q96N67,P07197,Q9Y5K6,P51114,P07196,O60313,O95816 21 +Chaperone complex 0.3443012650968504 0.6038917500343889 0.5459156141162711 1.0 0.8493077411251395 23 Q9NVR5 1 +Phagocytic vesicle membrane 0.3352943518414225 0.5954088275237953 0.5515702262491353 1.0 0.8519229302716859 26 Q93050,P50570,P51809,Q03519,Q9BZG1,Q9Y487,O75396,Q6WKZ4,Q99570,Q15907,Q03518 11 +Peptidase complex 0.2891904402541156 0.5942915413123704 0.5523171351626417 1.0 0.8519229302716859 59 P28074,P20618,Q96ES7,P61009,P28070,P49721,Q9UL46,Q05086 8 +Eukaryotic translation initiation factor 3 complex eif3m 0.4865188382803153 0.5843079730266665 0.5590131289459912 1.0 0.856988996753265 8 O15372,O15371 2 +Proteasome complex 0.3019350122421925 0.5767261317421902 0.5641244767061009 1.0 0.8608324518616967 44 P28074,Q05086,P49721 3 +Intrinsic component of endoplasmic reticulum membrane 0.2844204257480398 0.5632294406714738 0.5732786578843578 1.0 0.8706425875692713 63 Q9P0I2,Q9Y282,Q9NPA0,P61619,Q16799,Q9C0E8,Q9UM00,Q13586,Q9NQC3,Q9Y679,Q03518 11 +Copii vesicle coat 0.431083335507494 0.5610473325074294 0.5747652705989159 1.0 0.871418313488679 11 O75340,Q15436,O95487,Q9Y3B3,O94979 5 +Extrinsic component of cytoplasmic side of plasma membrane 0.3555831727456331 0.5561137834625152 0.5781330730709389 1.0 0.8717071333775541 17 Q14344,P61586,Q9Y4F1 3 +Tight junction 0.3324340700184106 0.5536234881990287 0.5798365478457639 1.0 0.8717071333775541 24 Q16625,O43815,Q12955,P16989,P55196,Q4VCS5,P11802 7 +Rnai effector complex 0.4999454467239073 0.5494437753565093 0.5827009395660459 1.0 0.8743173342225444 5 P26196,P06730 2 +Clathrin coated pit 0.341503887224471 0.5475164073813459 0.5840240014540252 1.0 0.8743173342225444 21 P50570,O95782,Q96D71,Q13492,P63010,Q8NC96 6 +Clathrin coat 0.3731362571680012 0.5468089105263634 0.5845100207512419 1.0 0.8743173342225444 15 O95782,Q96CW1,Q13492,P63010,Q8NC96 5 +Eukaryotic translation initiation factor 3 complex 0.380773386919792 0.5403865295251892 0.588930495578833 1.0 0.8794564089496619 14 O15372,O75822,O15371,P60228 4 +Protein dna complex 0.2834503169194704 0.5370620238877178 0.5912247717040975 1.0 0.8808169162722087 53 Q8NB78,P25205 2 +Envelope 0.2460244881664701 0.5341773821466776 0.5932188159869547 1.0 0.8814382740039111 492 Q99720,P11310,O43772,Q13505,P03886,Q70HW3,Q8TBP6,P00846,Q5BJF2,Q6P4A7,P62072,P14373,P09601,Q92575,Q9NRX2,O95168,Q13423,O60830,Q8WY22,O95831,Q86VD7,O75964,P33121,P50416,O43819,Q567V2,P56134,Q9P0J0,Q9Y5Z9,P13073,Q9Y371,P80303,Q8WWI5,P52888,O43676,Q96AY3,Q96RT1,Q9NUT2,Q9UDX5,Q96RL7,O14681,Q96IX5,Q9UI26,Q9GZY4,Q9H8M7,Q9BUK6,O15228,Q14739,Q5T9A4,Q13794,Q96CU9,O96000,Q15070,Q9NPL8,Q96EE3,Q9BSK2,Q16718,Q02218,O94901,Q9H9P8,P09669,Q9BUR5,P08574,Q9UKU0,P11802,Q9BQT8,Q8WXH0,Q9NVT9,Q9NQC3,Q9H3K2,Q9BZF3,Q96P70,P53701,Q9BYN8,Q96NB2,P10620,Q6P9B9,O60313,O96008,Q9Y619,Q9UH62,Q10713,Q9H974,Q9BYT8 84 +Exocytic vesicle 0.3025883215680903 0.5319847726252206 0.5947365420191308 1.0 0.8822254684768834 39 O15126,Q96A57,Q14141,Q13277,Q9NRW7,O43760,O43752,Q6IQ22,Q13614,Q9UI14,Q9BT78,Q15907 12 +Plasma membrane raft 0.3434105816755933 0.5224368425973277 0.6013662096168357 1.0 0.889106001966613 19 P41440,P09601 2 +Cohesin complex 0.4910110346959321 0.5180797038206884 0.6044026604159327 1.0 0.8894285363212846 5 Q8N3U4,Q8WVM7,O60216 3 +Endopeptidase complex 0.2818913761574877 0.5092137639748644 0.6106023963763973 1.0 0.8916620412780797 51 P28074,Q05086,P49721 3 +Membrane coat 0.300833457581155 0.5075661326488989 0.611757646745414 1.0 0.8916620412780797 37 P53621,O95486,Q8NDZ4,O00203,Q00610,O95782,Q96CW1,O75340,Q9Y678,Q9Y2T2,Q15436,Q13492,P63010,O95487,Q8NC96,O94973,Q9Y3B3,O94979 18 +Copii coated er to golgi transport vesicle 0.3063034190050744 0.5018448500337824 0.6157766616663809 1.0 0.8916620412780797 34 Q12907,Q9Y282,P04439,P49257,O14653,O95070,Q5BJH7,O75396,Q9Y3B3,O94979 10 +Ciliary plasm 0.416709110133566 0.4997892768290535 0.6172234619118215 1.0 0.8918779150279234 11 Q15555,Q10713 2 +Microbody 0.2772368516053619 0.4913653181190607 0.6231680893566456 1.0 0.8946770157483673 60 O75381,P48735,O96011,P33121,O75874,O43808,Q8N4Q0,O15254,A8MXV4,Q9UKU0,O15228 11 +Trans golgi network 0.2762370657214044 0.4848101347322812 0.6278110329609008 1.0 0.8984539301828276 61 O15126,Q96A57,Q8N2H4,P98194,P51809,Q14746,P40616,P20645,Q9UP83,Q9P260,O43752,Q9NPR9,Q9HAS0,Q9HC07,P83436,Q92538 16 +Site of polarized growth 0.2936786619020841 0.4833914659817174 0.6288178065213703 1.0 0.8984548819577338 41 Q99720,Q96N67 2 +Spindle midzone 0.3298389851292508 0.481441280425821 0.6302029036582595 1.0 0.8989955159214469 21 Q13432 1 +Copi vesicle coat 0.4419437868294866 0.4775713561722989 0.6329553220662225 1.0 0.90074401890371 9 Q9Y3B3 1 +Ubiquitin ligase complex 0.2727995000806631 0.4716502966500482 0.6371764197276948 1.0 0.901901923987321 66 Q9UJX3,Q9H1A4,O43791,O60566,Q6P2C8,Q9UBV2,Q96P70,Q14145,Q16763,Q9Y679,Q96K76 11 +Core mediator complex 0.4232662715418461 0.470076826442362 0.6383001298544086 1.0 0.901901923987321 10 Q6P2C8,O60244,Q71SY5 3 +Pore complex 0.4176421323808099 0.4482755476292565 0.6539543456846992 1.0 0.9149096867968372 10 P55196,Q07812,O96008 3 +Er to golgi transport vesicle membrane 0.3176083379507479 0.4470197690090903 0.6548607862431681 1.0 0.9149096867968372 23 O60763,P04439,Q9Y6Y8,P49257,O14653,O75340,P10321,Q15436,P49755,O75396,O95487,Q9Y3B3,O94979 13 +Sec61 translocon complex 0.4697741949430362 0.4456115269160294 0.6558778826790288 1.0 0.9149096867968372 4 P51571 1 +Translocon complex 0.4697741949430362 0.4456115269160294 0.6558778826790288 1.0 0.9149096867968372 4 P51571 1 +Distal axon 0.2749864443272276 0.4416037693704262 0.6587759558906678 1.0 0.9149096867968372 50 Q13641,Q99720,Q14141,P51114,P07196,Q13277,Q96N67,Q96A49 8 +Caveola 0.3727049263660317 0.43492528422698 0.6636166611994359 1.0 0.9163832439994292 13 P41440 1 +Death inducing signaling complex 0.4081765087605475 0.4148334787516235 0.6782638095331817 1.0 0.9274169345684344 3 P49327,Q13546 2 +Ciliary base 0.4591723039812281 0.4134306667894032 0.6792911102091144 1.0 0.9274169345684344 6 P17252,A0AVF1,P10644 3 +Ruffle 0.2791648052183781 0.4091669944220346 0.6824171141760094 1.0 0.9289611020719152 44 Q9Y5K6,Q4VCS5,Q9UHB6,P31751,P50570,P23396,Q9BZG1,Q9UQB8,Q10713,Q86YS7,Q9HCM4,P61586,Q7L576 13 +Brca1 c complex 0.4568670858575172 0.404965388521988 0.6855029526188208 1.0 0.9301025941008968 5 P49959,P38398,Q92878 3 +Ap type membrane coat adaptor complex 0.4053854684971683 0.4023562674891872 0.6874218500633726 1.0 0.9301025941008968 10 O95782,Q96CW1,Q9Y2T2,P63010,O94973 5 +Autophagosome 0.3015395896004462 0.3787215979313995 0.7048946132055591 1.0 0.9474236887025164 24 Q96A57,Q8TBX8,Q969Q5,Q9Y371,Q6IQ22,Q99570,Q9NRR5,Q9Y679 8 +Intracellular protein containing complex 0.2357369785207076 0.3740084979193513 0.7083979938349696 1.0 0.9498489617036454 230 P25205,O60762,Q9UL46,Q9NY27,Q6PD62,Q9UJX3,P30154,Q9H1A4,Q8TF05,Q96ES7,Q9UBV2,P49721,Q9HBM6,Q96K76,Q05086,P28074,O60566,Q6P2C8,O00411,O15160,O14802,Q96P70,Q14145,Q16763,Q9Y679,Q9Y2Z0,Q9UBU8,P42345,Q13616,O43791,P35269,Q9NRG0,P49005,P20618,O15514,Q9NR33,Q13555,P28070,Q9BXJ9,P19387 40 +Exoribonuclease complex 0.3337178642579546 0.3636307865105986 0.7161337340689482 1.0 0.9522751722974284 15 Q96B26,Q9NQT5 2 +Presynaptic active zone membrane 0.4418992359657515 0.3592611592458873 0.7193997277880206 1.0 0.9522751722974284 5 Q13277,P23634,P20020 3 +Cell leading edge 0.2600237950278837 0.3590179007769439 0.7195816979230669 1.0 0.9522751722974284 98 Q16625,P51809,O60749,Q9UQB8,Q10713,Q86YS7,P41440,Q7L576,Q00535,Q13418,Q92538,P50570,P31751,P23396,Q9BZG1,Q9Y2J2,Q9HCM4,P61586,O15145,O94832,Q8WXH0,Q13277,Q13576,Q4VCS5,Q9Y5K6,Q9UHB6 26 +Sperm connecting piece 0.342847875445993 0.35781506805561 0.7204817134917496 1.0 0.9522751722974284 2 P10644 1 +Coated vesicle 0.2612071102649535 0.3534400636794129 0.7237585549486083 1.0 0.9522751722974284 84 Q8NDZ4,P51809,P49257,Q5BJH7,O43752,O95070,Q8NC96,Q9Y3B3,O15126,P50570,O14653,O95782,Q9H267,O75396,Q12907,Q9Y282,P04439,O60763,P24390,Q13492,O43731,P20645,Q96CW1,P63010,O94979 25 +Spindle pole 0.2705524513266813 0.3532919429671914 0.7238695851717543 1.0 0.9522751722974284 44 Q96DB5,Q8WWK9,P50402,Q96SB8,P52732,P14635,Q13432,Q9Y6G9,Q8N3U4,P50748,Q96CW5,Q9UJW0,Q9ULW0 13 +Microtubule 0.254452014153088 0.3434860447916588 0.7312328375983341 1.0 0.9574646979110152 106 Q92598,Q15555,Q14203,Q9UQB8,Q13561,Q96CW5,Q9ULW0,Q00535,P43034,P50570,P29372,P36405,Q15813,Q9BRK0,Q96DB5,P50402,Q03001,Q13586,Q99426,Q9NQS7,Q9H6D7,Q15691,Q8WWK9,Q8IX90,Q9H6H4,P52732,Q9Y6G9,Q68CZ6,O43264,P50748,O15344,O00429,O60313,O95816,Q9Y5M8 35 +Postsynapse 0.2530529407968929 0.3418793972247593 0.7324416550635864 1.0 0.9576433352441912 108 Q99720,P57105,P52292,Q9UQB8,Q13614,Q7L576,Q00535,Q96RT1,P50570,Q9UBB6,P23396,Q12955,P35611,P61586,Q96A49,P46939,Q9Y4F1,Q13277,Q9NQC3,Q13492,P51991,Q9UEY8,P51114,P07196,O43815,Q96CW1,P63010,P62263 28 +Transcription factor tfiid complex 0.4336021514194505 0.3356973749114463 0.7370990855838833 1.0 0.958875254101129 6 P35269 1 +Clathrin coated vesicle membrane 0.3007768038666622 0.3338836533008158 0.7384673554280725 1.0 0.958875254101129 21 P20645,P51809,O95782,P63010,Q8NC96 5 +Mitotic spindle microtubule 0.4328406167380961 0.3335055306103941 0.7387527153657074 1.0 0.958875254101129 6 Q9H6D7,Q68CZ6 2 +Presynapse 0.2583653113226041 0.3309416469677169 0.7406885630379649 1.0 0.9599925787995685 87 Q96A57,Q9NRW7,O95295,O43752,Q9UQB8,Q6IQ22,Q13614,O14976,P41440,Q9UI14,Q7L576,Q9BT78,Q13641,O15126,Q14141,P50570,Q96A49,Q15907,Q13277,O43760,Q13492,P61981,P51114,P07196,Q96CW1 25 +Protein lipid complex 0.4311296426329672 0.3280363030104133 0.7428842141278351 1.0 0.9614429032118216 5 Q9BUR5 1 +Organelle envelope lumen 0.2730651915559666 0.322564719159641 0.7470249165781855 1.0 0.9654026780091456 36 O95831,P62072,P52888 3 +Microtubule associated complex 0.2697568263526713 0.3172125557454159 0.7510823234230777 1.0 0.9670893909602196 38 P29372,P52732,Q15555,Q14203,Q9Y6G9,Q68CZ6,Q53HL2,Q9H6D7,Q9NQS7,O15344,Q13561,Q96P70,Q9UJW0,O75935,O95793 15 +Schaffer collateral ca1 synapse 0.3218828844745544 0.3157361282089911 0.7522028020103719 1.0 0.9670893909602196 15 Q9UQB8 1 +Spindle microtubule 0.2775860296655295 0.3066593092230648 0.7591027048905667 1.0 0.9739636716483852 30 Q96DB5,Q00610,Q8IX90,P52732,Q68CZ6,P36405,Q9H6D7,Q15691,O43264,P50748,Q96CW5,P43034 12 +Neuron projection 0.2329012522371683 0.3036712209591245 0.7613783855458023 1.0 0.9754819200751814 191 Q99720,P11310,P51809,Q15555,Q9UH62,Q9UQB8,Q13614,Q9P265,Q13641,Q14141,Q9UBB6,Q12955,Q9Y2J2,P61586,P98179,Q96A49,O94832,Q9Y4F1,Q99729,Q13277,Q96N67,Q96F07,P51991,P07197,Q9Y5K6,P51114,P42345,P07196,O43815,Q13555,O60313,O95816,O95793 33 +Lsm2 8 complex 0.4205213207792707 0.2991088901934894 0.7648569632404485 1.0 0.9771348614788562 6 Q9Y4Y9 1 +R2tp complex 0.3715120051914355 0.2949516300214631 0.7680308303343841 1.0 0.9780444899931204 3 Q9H6T3,Q9Y230 2 +Aminoacyl trna synthetase multienzyme complex 0.3565387117761873 0.2787109879236729 0.7804666293891407 1.0 0.9844504535078772 11 P54136,Q9P2J5,Q15046,P41252,Q12904,P56192,O43324,Q13155,P07814,P47897 10 +Phagocytic vesicle 0.2582481537404176 0.2760499232714979 0.7825097221199304 1.0 0.9844504535078772 43 Q93050,P42345,P50570,P51809,Q03519,O43752,Q9BZG1,Q9Y487,O75396,Q6WKZ4,Q99570,Q15907,Q03518 13 +Ribonucleoprotein granule 0.2487354896044113 0.274901912241371 0.7833915979738748 1.0 0.9844504535078772 98 P60900,O75534,Q14011,Q01085,Q71RC2,Q9NR56,Q16637,Q7L8L6,Q9UN86,Q92600,P06730,P05198,P62487,P61978,P63000,Q92797,P07437,P62312,P50750,O00571,Q53R41,P42694,P26196,P67809,Q07065,Q13310,Q99729,Q92900,Q96C86,Q9BY77,P25787,P51991,Q08J23,Q99728,Q7Z417,P51114,Q9HCE1,Q92499,O15514,O95793 40 +Sperm principal piece 0.4105809802012383 0.2729201676177336 0.7849145833119917 1.0 0.9844504535078772 4 P23634,P08237,Q8WYA0 3 +Clathrin coated endocytic vesicle 0.2924231580542206 0.2691909964820703 0.7877827084076625 1.0 0.9866619335316168 18 P50570,P20645,P51809,O95782,Q96CW1,Q13492,P63010 7 +Phosphatase complex 0.3391645679514126 0.2621496216638954 0.7932060915054406 1.0 0.9893662629568338 12 Q9NY27,Q8TF05 2 +Mll3 4 complex 0.3601276498645124 0.2620723401103521 0.7932656710829709 1.0 0.9893662629568338 3 Q15291 1 +Actin based cell projection 0.2564950233034165 0.2549575771023536 0.798755865179428 1.0 0.9910162747783068 40 P46939,O94832,P51114,Q9Y4F1,Q00013,Q8WXH0,O95782,Q9UQB8,Q13576,Q7L576 10 +Cell division site 0.2745176731956977 0.2433519405538747 0.8077327707004964 1.0 0.9910162747783068 23 Q14141,O75935,P61586,Q96CW5 4 +Kinetochore microtubule 0.3974657327466779 0.2404005249583437 0.8100197712785511 1.0 0.9910162747783068 6 P50748 1 +Swi snf complex 0.3430138943680332 0.2386079762514928 0.8114095796061558 1.0 0.9910162747783068 11 Q12824 1 +Dendritic tree 0.2440343515900676 0.2383889179408704 0.8115794619060606 1.0 0.9910162747783068 94 Q9Y5K6,P51114,O94832,P42345,Q9UBB6,Q9Y4F1,Q99729,O43815,Q12955,Q13277,O95816,Q9UQB8,Q13614,Q96A49,O60313,P61586,P98179,Q9P265 18 +Cis golgi network 0.2998202007271336 0.2368558130400456 0.812768650697338 1.0 0.9910162747783068 15 P98194,O95249,Q9NPR9,Q16706,P24390,Q92538 6 +Rna polymerase ii holoenzyme 0.2674045105888082 0.2360463012111135 0.8133967419458052 1.0 0.9910162747783068 26 Q6PD62,P62487,Q96T76,P35269,O15514,Q9HBM6,P19387 7 +Transcription elongation factor complex 0.2754492082307539 0.2293415546358224 0.8186034581154096 1.0 0.9915246907406888 21 Q6PD62,Q08945,P55199,Q7KZ85,Q8IXH7,Q8WX92,P50750,Q15369,Q659A1 9 +Nuclear chromosome 0.2428216552441374 0.2292572996071373 0.8186689396238269 1.0 0.9915246907406888 92 Q9Y619,P25205,Q9BRX5,Q13547,Q9UBD5,Q9UNS1,O75717,Q9NQS7,Q9BRT9,Q13416,Q8N3U4,Q15021,Q9UEY8,Q9UBU8,P54652,Q9NRG0,P49005,Q9NR33,Q12824 19 +Condensin complex 0.39178613584336 0.2271312338164821 0.8203216975819989 1.0 0.9915246907406888 6 Q9NTJ3,Q15021 2 +Intrinsic component of peroxisomal membrane 0.3842105823470555 0.2259188187928729 0.8212645609036588 1.0 0.9915246907406888 7 O43808 1 +Endolysosome 0.376029788068734 0.2256062832154843 0.8215076535397348 1.0 0.9915246907406888 8 O95782,Q96CW1,O94973,P63010 4 +Synapse 0.2201612803507618 0.2205043768838428 0.8254783640043541 1.0 0.9922542659723068 228 Q99720,Q96A57,O95793,P57105,P52292,P51809,Q13432,Q9NRW7,O95295,O43752,Q9UQB8,Q6IQ22,Q13614,O14976,P41440,Q9UI14,Q7L576,Q00535,P05198,Q13641,Q9BT78,O15126,Q14141,Q96RT1,P50570,Q9UBB6,P23396,Q12955,P35611,P51812,P61586,Q96A49,Q15907,P46939,Q9Y4F1,Q05639,Q13277,O43760,Q9NQC3,Q13492,Q96F07,P62841,P51991,P61981,Q9UEY8,P51114,P07196,O43815,Q96CW1,P63010,P62263 51 +Escrt complex 0.3833721587955781 0.2083721217436384 0.8349384222015974 1.0 0.9938191466400444 6 Q9NZ09,Q9BRG1,Q99816 3 +Cleavage furrow 0.2742102951884641 0.2007955416604387 0.8408584491737852 1.0 0.9950251492486571 17 Q14141,O75935,P61586 3 +Synaptic vesicle membrane 0.2831314449932843 0.1868808533156061 0.8517540515632402 1.0 0.9950251492486571 15 O15126,O43760,P20020,O95295,O43752,P20339,Q15907 7 +Intrinsic component of mitochondrial outer membrane 0.2888091530550015 0.1854867835159929 0.8528472456266749 1.0 0.9950251492486571 14 Q8IXI1,P50416,Q8TB36,Q9UH62,O96008 5 +Ino80 complex 0.3716325868224657 0.184696319703861 0.853467232966455 1.0 0.9950251492486571 4 Q9Y5K5,Q9Y230,O96019 3 +Rpap3 r2tp prefoldin like complex 0.3717532467532536 0.1844175224803016 0.8536859246140855 1.0 0.9950251492486571 5 Q9UHV9,Q9H6T3,Q9Y230,P19388 4 +Germ cell nucleus 0.3650895210078518 0.183965096291315 0.8540408366779839 1.0 0.9950251492486571 7 P54652 1 +Proteasome accessory complex 0.2654924983692107 0.1833285402447569 0.8545402419939656 1.0 0.9950251492486571 19 P48556,P43686,P17980,P62333,P62191,Q9UNM6,Q06323,P62195,O43242,O00487,Q15008,Q99460,O00231,Q9UL46,P51665,P61289,Q13200,O00232 18 +Golgi apparatus subcompartment 0.2338091865781559 0.1810370041708057 0.8563385307505522 1.0 0.9950251492486571 83 Q96A57,P51809,O43752,Q10713,Q92538,O15126,P50570,Q9BZG1,Q9NPR9,Q9HC07,P04439,P98194,Q14746,P40616,Q9P260,P83436,Q8N2H4,P20645,Q9UP83,O95249,Q9HAS0,Q16706,Q7L5N7 23 +Terminal bouton 0.3685305652126132 0.1781180374785086 0.8586302766806087 1.0 0.9950251492486571 5 O14617,P20339,Q7L576 3 +Zona pellucida receptor complex 0.3681818181818261 0.1774459420026604 0.8591581233373975 1.0 0.9950251492486571 5 P50991,P49368,P78371,P50990 4 +Transcription regulator complex 0.2285043343719486 0.1582316964576086 0.8742742282013758 1.0 0.9997487871935824 81 Q71SY5,Q99729,O75376,P35269,Q9BZK7,Q6P2C8,Q9Y2X0,Q9Y5Q8,Q13547,Q5TKA1,Q9BXJ9,Q9HBM6,O60244,P11802,Q9UKN8 15 +Proteasome regulatory particle 0.2652329749104 0.1571112476079118 0.8751571733615924 1.0 0.9997487871935824 16 P48556,P43686,P17980,O00232,P62191,Q9UNM6,P62195,O00487,Q15008,Q99460,O00231,P51665,O43242,Q13200,P62333 15 +Cytoplasmic side of endoplasmic reticulum membrane 0.3568900890788316 0.1567017586651393 0.8754799009914687 1.0 0.9997487871935824 5 Q8TCT9,P31689 2 +Clathrin coated endocytic vesicle membrane 0.2761377738304473 0.1543585819751358 0.8773270089970486 1.0 1.0 14 P20645,P51809,O95782,Q96CW1,P63010,P20339,O94973 7 +Costamere 0.3529170743329148 0.1496628390925352 0.8810306279994706 1.0 1.0 6 P51114,Q12955 2 +Endocytic vesicle 0.2265484148799138 0.1490855360525431 0.8814861388956412 1.0 1.0 83 Q16625,P51809,Q03519,O43752,Q9Y487,Q99570,P50570,O95782,Q969Q5,Q5KU26,Q9BZG1,O75396,O00161,Q15907,Q93050,P04439,Q13492,Q14C86,Q6WKZ4,Q4VCS5,Q03518,Q9Y5K6,P42345,P20645,Q96CW1,Q8WTV0,Q13555,P63010 28 +Trans golgi network transport vesicle membrane 0.3488808680930521 0.1436807182269418 0.8857525978224559 1.0 1.0 4 O95782,Q00610 2 +Proteasome regulatory particle lid subcomplex 0.3466959141446072 0.1394577871005306 0.8890884109273263 1.0 1.0 6 O43242,O00232,O00487,O00231 4 +Sin3 type complex 0.3303045947007659 0.1334001203320416 0.8938769502477624 1.0 1.0 8 Q9UBU8 1 +Crd mediated mrna stability complex 0.3390711269892857 0.1277708922251457 0.8983302858614028 1.0 1.0 6 Q9NZI8,P67809,O75534,O60506,Q08211 5 +Proton transporting v type atpase complex 0.2904210784751088 0.1216039984002372 0.9032126467283256 1.0 1.0 11 Q9Y5K8,Q9Y487 2 +Clathrin coated vesicle 0.2188288929721125 0.1206356381555398 0.903979639805382 1.0 1.0 41 O15126,P50570,P51809,P20645,O95782,Q96CW1,O43752,Q9H267,Q13492,P63010,Q8NC96 11 +Intrinsic component of presynaptic active zone membrane 0.3323462636961983 0.1188072576815763 0.9054280586154722 1.0 1.0 4 P23634,P20020 2 +Integral component of presynaptic active zone membrane 0.3323462636961983 0.1188072576815763 0.9054280586154722 1.0 1.0 4 P23634,P20020 2 +Saga type complex 0.3087883549325487 0.1175226823359579 0.9064458706843236 1.0 1.0 9 Q9HBM6,Q96ES7 2 +Cytosolic small ribosomal subunit 0.2210214802565201 0.1149815811357218 0.9084597213297212 1.0 1.0 30 P23396,P08708,P46783,P62841,P62263,P05198 6 +Perinuclear endoplasmic reticulum 0.3245619241088009 0.1081377836409255 0.9138863968618208 1.0 1.0 5 Q9BZF3,P51572 2 +U6 snrnp 0.3146791034281175 0.1023986120106949 0.9184402853375104 1.0 1.0 7 Q9Y4Y9 1 +Set1c compass complex 0.3145934463916116 0.0962992038964675 0.9232829433484544 1.0 1.0 5 Q15291 1 +Platelet alpha granule 0.2289548488236477 0.0893502048356412 0.9288035958989872 1.0 1.0 16 Q9UHQ9,P51809 2 +Actin filament bundle 0.2058293790023143 0.0853381307499781 0.9319925781295144 1.0 1.0 27 P29966,Q9Y613,Q13418 3 +Proton transporting v type atpase v1 domain 0.2976145136958901 0.0838996631393289 0.9331362073936148 1.0 1.0 7 Q9Y5K8,P21281,Q15904 3 +Tho complex 0.2951235224323622 0.0771344845656835 0.938516559993906 1.0 1.0 5 Q96FV9,Q96J01 2 +Chromosome passenger complex 0.2908882269422208 0.0736887132254941 0.9412580799129636 1.0 1.0 4 Q9NQS7 1 +Nucleocytoplasmic transport complex 0.2748538011695907 0.0654795524034847 0.9477921862101666 1.0 1.0 7 Q9BQG0,P52292,O00505,P62826,Q14974,Q9HAV4 6 +Elongin complex 0.2469175859831203 0.0644163149380874 0.948638739564158 1.0 1.0 3 Q15369,Q14241 2 +Nls dependent protein nuclear import complex 0.2746753246753312 0.0621210225367511 0.9504664557651544 1.0 1.0 5 P52292,Q14974,O00505,Q9BQG0 4 +Exon exon junction complex 0.2743462452429116 0.0618227054858013 0.9507040217077554 1.0 1.0 4 Q9Y5S9 1 +Cilium 0.1903463951373668 0.060890243066757 0.9514466199332888 1.0 1.0 72 Q9Y5K8,Q9NUQ9,Q14141,Q15555,Q96RL7,Q9BZG1,Q10713,P28070,Q99570,Q92973,Q96J42,A6NIH7 12 +Eukaryotic translation initiation factor 2b complex 0.270235821968535 0.0593434101533799 0.952678585715431 1.0 1.0 4 P05198 1 +Cell cortex 0.1713743026546379 0.0586463452028285 0.953233796049176 1.0 1.0 94 Q02952,Q14203,Q86YS7,P41440,P43034,Q14141,P63000,P31751,P29966,Q14651,Q9UJW0,P61586,P28289,P63096,P46939,O94832,P50402,Q00013,P60981,Q03001,Q12797,P11171,Q13586,Q14019,Q96J02,Q96KP1,Q15691,O00471,O94915,Q9UEY8,P56545,Q9P0K7,Q9NV70,Q9UM54 34 +Polysome 0.1698981268485077 0.0577885591743153 0.9539170514062136 1.0 1.0 42 Q02878,P60900,P13639,P62701,P62424,Q07020,P83731,P83881,P05198,O15372,Q92615,P62906,P62273,P23396,P62753,P08670,Q02543,P63173,Q04637,P84098,Q08211,P27797,P35580,P62910,P62913,P63220,Q06787,Q8TCS8,Q6PKG0,P62888,Q92616,Q7Z417,Q9Y295,P51114,P61758,P62266,Q00341,Q9Y3U8,P62917,P20290,P25786 41 +Contractile ring 0.2607989607015339 0.0548318830795781 0.9562723995779364 1.0 1.0 6 P46939,Q96Q89,Q9NQW6,O43663,P35579 5 +Retromer complex 0.2192663427708628 0.0470782041864565 0.9624508986122527 1.0 1.0 9 Q9UBQ0,O60749 2 +Proton transporting two sector atpase complex catalytic domain 0.1581376571118741 0.0416347722022006 0.966789853056156 1.0 1.0 11 Q9Y5K8,P36542,Q15904,P21281,P21283 5 +Ctf18 rfc like complex 0.2203162204386362 0.0409400516921521 0.9673436875657376 1.0 1.0 4 P40938 1 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a460edb9f1c6e9d9f06b0a075e88a89065a127ad --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atp binding cassette abc transporter complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Calyx of held", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna recombinase mediator complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Muscle myosin complex", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class i", "Phosphatidylinositol 3 kinase complex class ia", "Phosphatidylinositol 3 kinase complex class iii", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Serine type endopeptidase complex", "Serine type peptidase complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilium bundle", "Stereocilium membrane", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquinone biosynthesis complex", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPGK", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C12orf73", "C14orf2", "C17orf75", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C3orf58", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARS2", "CASK", "CAST", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC22", "CCDC47", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPI", "CENPP", "CENPQ", "CENPU", "CENPV", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CISD3", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLTB", "CLTC", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DOLK", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP3", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM162A", "FAM207A", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP4", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMC1", "FMR1", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCX", "GGH", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD5", "HDLBP", "HEATR1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOXD11", "HP1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ISCU", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "IVD", "JAGN1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LETMD1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "M6PR", "MACF1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD8", "MGAT1", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NEPRO", "NES", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPM1", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C3A", "NTHL1", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT12", "NUDT19", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAK1IP1", "PAK4", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PECR", "PEDS1", "PEF1", "PELP1", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHIP", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRSS3", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPS1", "ROMO1", "RP2", "RPA1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSRC1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT2", "SIGMAR1", "SIN3A", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35A4", "SLC35B2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPOP", "SPOUT1", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM29", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TKT", "TLE3", "TLN1", "TM7SF2", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM192", "TMEM201", "TMEM214", "TMEM223", "TMEM230", "TMEM33", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBIAD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "USMG5", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H13", "ZC3H14", "ZC3H18", "ZC3H8", "ZC3HC1", "ZCCHC17", "ZCCHC8", "ZDHHC20", "ZEB2", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF148", "ZNF326", "ZNF346", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["ABAT", "ABCB8", "ACADM", "ACADVL", "ACBD3", "ACOX3", "ACSL1", "ACSL6", "ACTL6A", "ADD1", "ADD3", "ADPGK", "AFDN", "AHCYL1", "AIFM1", "AIMP1", "AIMP2", "AKAP12", "AKAP8", "AKT2", "ALG13", "ALKBH5", "AMOT", "ANAPC1", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3M1", "APOO", "ARL1", "ARL3", "ARMC1", "ARMCX3", "ARPC3", "ASPH", "ATAD3B", "ATP13A1", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5C1", "ATP5J2", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP7B", "AUP1", "BAG2", "BAIAP2", "BARD1", "BAX", "BCAP29", "BCAP31", "BCCIP", "BCLAF1", "BCOR", "BICD2", "BRCA1", "BRI3BP", "BTF3", "BUB1B", "C17orf75", "C19orf70", "C2CD5", "C3orf58", "CALR", "CALU", "CAMK2G", "CBX1", "CCDC134", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT8", "CD2AP", "CDCA8", "CDK2", "CDK4", "CDK5", "CDK9", "CELF1", "CHCHD3", "CHD8", "CHEK1", "CHORDC1", "CHP1", "CHRAC1", "CIRBP", "CKAP2", "CKAP4", "CLTC", "CNOT9", "COA1", "COG2", "COG5", "COG7", "COL4A3BP", "COLEC12", "COPA", "COPG1", "COPS4", "COTL1", "COX4I1", "COX6C", "CPT1A", "CSDE1", "CTBP2", "CTR9", "CUL1", "CYB5B", "CYB5R1", "CYC1", "CYFIP1", "CYFIP2", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DDRGK1", "DDX1", "DDX3X", "DDX6", "DHCR24", "DHX9", "DIP2B", "DNAAF2", "DNAJA1", "DNAJC10", "DNAJC3", "DNM1L", "DNM2", "DOCK7", "DPM1", "DRG1", "DST", "DSTN", "DYNC1LI1", "EEF1A2", "EEF1E1", "EEF2", "EI24", "EIF2S1", "EIF3D", "EIF3E", "EIF3H", "EIF3J", "EIF4B", "EIF4E", "EIF4G1", "EIF4G3", "EIF5A", "ELL", "ELOA", "ELOC", "ELP1", "ELP2", "EMC3", "EMC7", "EMD", "EPB41", "EPB41L3", "EPB41L5", "EPRS", "ERAP1", "ERBIN", "ERGIC3", "ERMP1", "EXOC1", "EXOC2", "EXOC5", "EXOSC2", "EXOSC3", "EXOSC8", "FAM3C", "FAM49B", "FARP1", "FASN", "FASTKD1", "FASTKD5", "FHOD1", "FKBP10", "FKBP14", "FKBP2", "FKBP9", "FMR1", "FOXRED1", "FRYL", "FXR1", "G3BP2", "GABARAPL2", "GAK", "GAPVD1", "GBF1", "GCN1", "GDAP1", "GEMIN4", "GEMIN5", "GGCX", "GHITM", "GIGYF2", "GINS3", "GINS4", "GNA13", "GNAI1", "GNAI3", "GNPAT", "GOLT1B", "GOSR1", "GOSR2", "GPR108", "GPS1", "GPX8", "GRB2", "GTF2F1", "GTF3C4", "GTF3C5", "HAUS3", "HAUS4", "HCCS", "HDAC1", "HDLBP", "HELZ", "HINT2", "HLA-A", "HLA-C", "HM13", "HMOX1", "HMOX2", "HNRNPA3", "HNRNPAB", "HNRNPD", "HNRNPK", "HS2ST1", "HSD17B12", "HSD17B7", "HSPA2", "HSPH1", "IARS", "ICE2", "ICMT", "IDH1", "IDH2", "IFT81", "IGF2BP1", "ILK", "ILVBL", "INCENP", "INTS5", "IPO11", "IPO9", "IQGAP2", "ITCH", "KARS", "KDELR1", "KDELR3", "KDM1B", "KEAP1", "KIAA0319L", "KIAA1468", "KIF11", "KIF20B", "KMT2A", "KNTC1", "KPNA2", "KPNA3", "KPNB1", "L2HGDH", "LARP1", "LARP4", "LARP4B", "LARS", "LBR", "LDAH", "LETMD1", "LIMA1", "LIN9", "LMAN1", "LMAN2", "LNPK", "LPCAT2", "LRRC8C", "LSM5", "LSM6", "M6PR", "MAN1A2", 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sha256:b89aa03bcf9f171629bfd615e72f6f6e7ee92f7386f270091541dd7a82b7efdf +size 243030 diff --git a/msigdb_gomf/df_merge.tsv b/msigdb_gomf/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3156cd1eee1b194e7e99b5eb8ad7936bf1567d07 --- /dev/null +++ b/msigdb_gomf/df_merge.tsv @@ -0,0 +1,23 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Oxidoreductase activity 38 238 3.190844716101528 0.001418575015613 52.54126213592233 227.42961165048544 0.490492706528076 0.5955656171597654 20.033606385640603 16.688970744458114 1.2909283370539455 0.4039853598071011 7.938489390066197e-05 0.0003779820851204 1.2402808225511512e-05 4.869005061864318e-06 1.2633320645655318e-06 +Flavin adenine dinucleotide binding 6 31 3.153244988202217 0.0016146623547703 7.37621359223301 27.813106796116504 0.6719710250262334 0.465219074258643 3.908755076189923 2.8788689557398657 1.0329905694282788 0.3336749641062707 3.412640740991299e-05 0.0032330061916283 0.0003255691608431 0.0039146432776675 0.0310034208397513 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 8 28 2.4836779381971725 0.0130033351603175 9.395631067961164 29.8373786407767 1.5709767518568172 0.2393367467664754 3.119976403291062 3.762391942431812 1.2135099906711824 0.3124947384976632 0.0959255242498469 0.0734458650364987 0.0126378967280994 0.007590847384062 0.0152461030289283 +Fad binding 4 11 2.413605139486464 0.0157955699099381 3.78883495145631 9.932038834951456 1.575439945642976 0.1698004033102896 1.8828741719818296 1.250336932628077 0.9196006746446306 0.2289411404885479 0.0003390957715298 0.0068317681715133 0.0001061075299203 0.0033995973847004 0.0077027418898757 +Organic cation transmembrane transporter activity 4 7 2.2020118064716887 0.0276644744995229 1.9271844660194175 5.04126213592233 1.6158747778246996 0.14183106997637 1.275055237696066 0.9168044752551467 0.8418646651592007 0.1871331589544055 0.0150080037348002 0.001984476440523 0.0002990720728516 0.0002865546760543 0.0003811527509218 +Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity 1 5 2.197250904556859 0.0280025318744923 1.83252427184466 5.0 -0.4959735337725789 0.392785827701451 1.1920490789780558 0.0 1.0690815977866477 0.2666518790995129 0.0053836994107949 0.0002241871259369 0.0009157120850054 0.0056579443580751 0.0216592314955336 +Metallopeptidase activity 8 37 2.19248843462162 0.0283442572874137 11.548543689320388 40.60436893203884 1.2053444242445344 0.3510417366391842 4.586289489033314 2.1135899474190585 1.0988837346562612 0.3462572593421246 1.0 0.3208381238265493 0.0426450873703444 0.0457163514521504 0.0158464797196496 +Molecular carrier activity 8 32 2.156444189013029 0.0310489973318284 8.985436893203884 32.922330097087375 0.4263347027610819 0.5995318029338973 4.267144921372851 3.1428430650945036 0.9199841946557948 0.3455794463799358 1.0 0.0305319028295214 0.1057169178564165 0.0124412460735711 0.0062070298083063 +Histone methyltransferase activity 7 21 2.121310188311469 0.0338957075538428 5.097087378640777 18.237864077669904 0.1244895512019806 0.4941614121988424 3.313006328716042 3.142524385825145 1.057643161070896 0.3213310584694642 0.0557427329493798 0.0020640692536444 0.0146485330026984 0.0400103397181721 0.0141141978450259 +Ubiquitin like protein specific protease activity 10 27 2.119285808681884 0.0340663202443665 10.106796116504857 31.75728155339806 -0.0087868977314459 0.6462289751626873 5.541831426556863 5.0913328588839075 0.8105154089168884 0.3059411300071647 1.0 1.0 0.6393791109962035 0.7261511530299896 0.5807912610205243 +Dioxygenase activity 4 17 2.110625944796212 0.0348044758153078 4.966019417475728 18.946601941747577 0.431149201997438 0.5860948271154753 2.499283524441613 3.0888246903576806 0.809438844885216 0.3223440754880037 1.0 0.2801168002074996 0.1411421437582085 0.0843199651347959 0.238898101438993 +N methyltransferase activity 9 28 2.1009915869993785 0.0356417047709261 7.150485436893204 23.66990291262136 -0.0832039707190082 0.5601088618039707 4.112103229277509 4.489228423151826 0.900127227300695 0.2985520698577362 0.08801559577904 0.0078165677457274 0.049541392930243 0.1539030213852019 0.0227409192206126 +Lysine n methyltransferase activity 2 15 2.095782940087799 0.0361014503886907 3.883495145631068 11.9247572815534 -0.0369724089451057 0.480421409378244 2.6859973862076445 2.891512301147913 1.047471283755547 0.3016369204295391 0.0577898017123185 0.0022960708364777 0.0161789595718159 0.1505670934775949 0.05097722419406 +Histone lysine n methyltransferase activity 2 15 2.095782940087799 0.0361014503886907 3.866504854368932 11.91019417475728 -0.0358842564515071 0.480524731019508 2.6883684042855625 2.893614154464538 1.0490872999314411 0.3023651592060449 0.0423379310763625 0.0009094910101507 0.0067632743899401 0.0734338910721259 0.0124112269486536 +Membrane insertase activity 3 8 2.083555818927961 0.0372005893290459 2.737864077669903 7.388349514563107 0.8099367695235317 0.306513025583228 1.5809003521008822 1.7333564146948666 1.2685525479217892 0.3048480656363501 1.0 0.001984476440523 0.0078714328443906 0.0042908003473226 0.003831161384841 +Protein carrier chaperone 3 11 2.0755340858060696 0.0379370631823112 3.3980582524271843 10.118932038834952 0.8288787693114796 0.3398938251553178 1.8569721980092944 2.0920401213092656 1.1849901066971258 0.3127406939001886 1.0 0.0032958763634803 0.012905013470629 0.0089509329804495 0.0100261737850475 +Nadh dehydrogenase activity 6 25 2.0708330267855377 0.0383744026647192 6.62621359223301 21.9004854368932 0.6460127731992702 0.4045936795236815 3.355345283841267 2.6889381015310834 1.101850132292176 0.306596625090648 0.0454466093944714 0.187449079081247 0.0082729445560879 0.00057064251751 0.0009907392825374 +Cation transmembrane transporter activity 24 78 2.0646535834171247 0.0389557893854066 25.62135922330097 70.51699029126213 1.766742880952279 0.2698419237572138 12.29126021871486 8.422243011776631 2.00238274385689 0.3706372466673562 0.2229161299668443 0.0990971562045587 0.0247865178565085 0.0043747711154334 0.0001588083620728 +Proline rich region binding 1 6 2.0208253295532943 0.0432978497824727 1.1529126213592231 5.186893203883495 0.8836697013404169 0.3769016216180994 1.161024096877417 0.956085799787736 0.8816524975681769 0.2959695633458655 1.0 0.0026008925831016 0.0102498345034834 0.0569248849368824 0.1829832713301316 +Metalloexopeptidase activity 4 18 2.010032401477127 0.0444277596482387 5.395631067961165 20.067961165048544 0.9825976981990544 0.3457114951896768 2.1791777953827336 1.4039620491256346 0.996651753778752 0.2995335114577974 1.0 0.1553991536419083 0.0046396659223567 0.0530915597366878 0.0265417931189519 +Transporter activity 51 187 2.007134170874551 0.0447353786448794 62.22330097087379 172.27912621359224 2.173366592838491 0.2707201784543502 25.984753572620328 19.29276868436311 2.593156143256053 0.3916539604106395 0.1049527237588666 0.036948172273385 0.0014722134053986 6.538350507276125e-05 5.396259229582652e-07 +Demethylase activity 3 9 2.0018810115328995 0.0452975303379212 2.1480582524271843 9.817961165048544 0.6057169859432091 0.4825187541655972 1.8354442113334128 1.8284079016462729 0.8653710828279827 0.3154015669224607 0.0371363420154888 0.1553991536419083 0.045127039841821 0.0100334254948701 0.0898423824366987 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2b9185e51cbea049f154ef47ce90787a8cce3ef2 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 1361, + "title": "Average number of proteins per term", + "value": 16.03232916972814 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f6d6d6765a340e603a049ede4278f942f3186a35 --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f278c8695117eb51f60c898f2b9467bf0ecfedbf --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,384 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Histone h3 methyl lysine 36 demethylase activity 0.942264028543624 3.239956871410261 0.0011954778010143 0.803681828363672 0.0146580656502752 2 Q9Y2K7 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.938371715861172 3.2230639150371014 0.001268272507664 0.8222210588014764 0.0147834260054131 2 P09601 1 +Oxidoreductase activity 0.3697897866094203 3.1908447161015276 0.001418575015613 0.8551492388926742 0.016224206691171 238 P13073,P11310,Q8NB78,Q15392,P49419,P03886,Q8N4Q0,P56937,Q16718,Q02218,P30837,O43676,Q9H9P8,P48735,P00374,Q32P28,Q8TED1,Q8N0U8,Q9H6W3,P13674,Q9Y2K7,P08574,Q53GQ0,P09601,P78417,P30519,Q6P6C2,O95168,O15254,Q13423,O95831,Q14739,O75874,O43819,Q96CU9,O96000,Q9UHQ9,Q9P0J0 38 +Flavin adenine dinucleotide binding 0.6515925989472846 3.153244988202217 0.0016146623547703 0.8891227485073508 0.0178663045922152 31 P11310,Q8NB78,Q15392,O15254,A1L0T0,O95831 6 +Cytoskeleton nuclear membrane anchor activity 0.8936101200129734 3.0262514696038325 0.0024760628092064 0.965751086987584 0.024070867738071 2 O94901 1 +Vascular endothelial growth factor receptor binding 0.8861498540382733 2.99298648043514 0.0027626198683172 0.9768353726872264 0.0262931862991595 2 Q9H2J4 1 +Mannosyl oligosaccharide mannosidase activity 0.879987025624386 2.965405234362944 0.0030228445997231 0.9837607185237104 0.0272456390743256 2 O60476 1 +L ornithine transmembrane transporter activity 0.8718780408692809 2.928973410942134 0.0034008351240693 0.9903077137178656 0.0298474339290676 2 P30825 1 +14 3 3 protein binding 0.8595523840415165 2.8732886521209746 0.0040622277493378 0.9960732841879144 0.0333053732942699 2 P85037 1 +Cardiolipin binding 0.8462536490431372 2.8127869762083564 0.0049114176281117 0.9987702057189384 0.0371357743992228 2 O60313 1 +Phosphatidylglycerol binding 0.8462536490431372 2.8127869762083564 0.0049114176281117 0.9987702057189384 0.0371357743992228 2 O60313 1 +Tap1 binding 0.8306843983133231 2.7413955565519363 0.0061178807344708 0.9997640781874838 0.0429197715444062 2 Q03518 1 +Er retention sequence binding 0.803762568926363 2.6165064473234847 0.0088834686655356 0.9999946820537832 0.0559740780268244 2 P24390 1 +Histone h3 methyl lysine 4 demethylase activity 0.9046557986590466 2.581460146334267 0.0098383350138275 0.9999985677683124 0.0591503328178479 3 Q8NB78 1 +Procollagen proline dioxygenase activity 0.8998938058675461 2.56166120052043 0.0104172885037461 0.9999993538888884 0.0609871592256614 3 Q32P28 1 +Peptidyl proline dioxygenase activity 0.8998938058675461 2.56166120052043 0.0104172885037461 0.9999993538888884 0.0609871592256614 3 Q32P28 1 +Phosphatidylinositol monophosphate phosphatase activity 0.8876710645602696 2.5106364505327474 0.0120513737093614 0.9999999318499364 0.0683413317435041 3 Q9C0I1 1 +Pattern recognition receptor activity 0.7778138177100229 2.494385140253498 0.0126175555125078 0.9999999687657476 0.0712551578942872 2 Q8WTV0 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.5783757692554682 2.4836779381971725 0.0130033351603175 0.9999999816495176 0.0719412160698872 28 Q6P6C2,Q8NB78,Q32P28,Q9H6W3,P13674,Q9Y2K7,P09601,P30519 8 +Phosphatidylinositol 3 kinase binding 0.772624067466751 2.469754049820889 0.0135205975634598 0.9999999910092174 0.0741997309833419 2 P50570 1 +Fad binding 0.8055150559395341 2.413605139486464 0.0157955699099381 0.9999999996117472 0.0811863685117177 11 O95831,Q8NB78,Q15392,O15254 4 +Mannosidase activity 0.8587702938563216 2.388805705008265 0.0169032389856647 0.9999999999161472 0.084268528423039 3 O60476 1 +Histone methyltransferase activity h3 k9 specific 0.8569110966904439 2.3809114183022375 0.0172698642376993 0.9999999999495284 0.0857332662629942 3 Q96KQ7,Q15047 2 +Manganese ion transmembrane transporter activity 0.8533419857235405 2.3657374797102366 0.0179941987285243 0.9999999999814976 0.0874646588197202 3 Q9HC07,Q9HD20 2 +Tau protein kinase activity 0.7460265974699964 2.342436451637851 0.019158296275259 0.9999999999963176 0.0911693749322639 2 Q00535 1 +Folic acid binding 0.845976906658854 2.3343452767478707 0.0195776497357147 0.9999999999979424 0.0927772434212529 3 P41440 1 +Unmethylated cpg binding 0.9492824186227428 2.333298006684927 0.0196325099965619 0.9999999999980932 0.0927772434212529 4 Q03164 1 +Peptide alpha n acetyltransferase activity 0.8450442907740023 2.3303625211837584 0.0197869988869761 0.9999999999984612 0.0931837560040639 3 Q86UY6 1 +Thioredoxin disulfide reductase activity 0.7330522218618188 2.2796742628792717 0.0226270148507063 0.9999999999999704 0.1023101900724631 2 Q6DKJ4 1 +Phosphatidylinositol bisphosphate phosphatase activity 0.8320682896052498 2.2747700241810924 0.0229197293261038 0.9999999999999802 0.1029754791242314 3 Q13614 1 +Mhc class ib protein binding 0.8309539260220575 2.26998033968131 0.0232087759389987 0.9999999999999868 0.1038558085306822 3 Q9NUQ9,Q03518 2 +17 beta hydroxysteroid dehydrogenase nadpplus activity 0.8298959874664849 2.2654309200695275 0.0234862486955673 0.999999999999991 0.1044600799825725 3 Q53GQ0 1 +Rna polymerase i transcription regulatory region sequence specific dna binding 0.8288389179043469 2.260883042701476 0.0237665004519027 0.999999999999994 0.1053622381597382 3 Q12824 1 +Azole transmembrane transporter activity 0.7178073305222076 2.2053833058645083 0.0274272085024382 1.0 0.1166513461619328 2 P30825 1 +Organic cation transmembrane transporter activity 0.8819703972112439 2.2020118064716887 0.0276644744995229 1.0 0.1172939245914351 7 Q8WWI5,Q86VD7,Q70HW3,O43772 4 +Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity 0.9097922552837616 2.197250904556859 0.0280025318744923 1.0 0.1183585275813168 5 P49419 1 +Metallopeptidase activity 0.4973661971008041 2.1924884346216196 0.0283442572874137 1.0 0.1194319943287 37 Q9NZ08,P55786,O43847,Q10713,P52888,Q969V3,Q9NQH7,Q7Z2K6 8 +O acetyltransferase activity 0.8086745035572216 2.173710964918632 0.0297268486728849 1.0 0.1226677428668935 3 O15228 1 +Molecular carrier activity 0.5173392950392 2.156444189013029 0.0310489973318284 1.0 0.1261423443839357 32 Q9P0I2,Q9UI26,O43819,P62072,Q96P70,Q92973,Q15070,Q9NPA0 8 +Serine transmembrane transporter activity 0.8017096566315416 2.143418468508969 0.0320795114260126 1.0 0.1295555342753803 3 Q15758 1 +Ribose phosphate diphosphokinase activity 0.7012650016217927 2.124110925876464 0.0336608691073117 1.0 0.13365443279845 2 Q14558 1 +Diphosphotransferase activity 0.7012650016217927 2.124110925876464 0.0336608691073117 1.0 0.13365443279845 2 Q14558 1 +Histone methyltransferase activity 0.5736251696191421 2.121310188311469 0.0338957075538428 1.0 0.1337161100892177 21 Q9H7B4,Q03164,Q86X55,Q96KQ7,Q15047,O96028,Q9H9B1 7 +Ubiquitin like protein specific protease activity 0.5357663898174989 2.1192858086818833 0.0340663202443665 1.0 0.1340007567993723 27 O15372,P45974,Q9NUQ7,Q9H4L4,Q9NP73,Q86UV5,Q9H8M7,Q9P275,Q96K76,Q9BT78 10 +Dioxygenase activity 0.6037315818315881 2.110625944796212 0.0348044758153078 1.0 0.1353396902418115 17 Q6P6C2,Q9H6W3,Q9Y2K7,Q32P28 4 +N methyltransferase activity 0.5278063469874136 2.1009915869993785 0.0356417047709261 1.0 0.1378078414580409 28 Q9H7B4,Q03164,Q86X55,O75648,Q7Z2T5,Q96KQ7,Q15047,O96028,Q9H9B1 9 +Lysine n methyltransferase activity 0.6386604984592559 2.095782940087799 0.0361014503886907 1.0 0.1384058421943889 15 Q03164,Q15047 2 +Histone lysine n methyltransferase activity 0.6386604984592559 2.095782940087799 0.0361014503886907 1.0 0.1384058421943889 15 Q03164,Q15047 2 +Membrane insertase activity 0.8283104164693637 2.0835558189279615 0.0372005893290459 1.0 0.1414245868067918 8 Q9P0I2,Q15070,P62072 3 +Protein carrier chaperone 0.7358550204373195 2.0755340858060696 0.0379370631823112 1.0 0.142630781743441 11 Q9P0I2,Q15070,P62072 3 +Nadh dehydrogenase activity 0.5394232510748767 2.0708330267855377 0.0383744026647192 1.0 0.1434823132601178 25 O43676,P03886,O95168,O96000,O95831,Q9P0J0 6 +Cation transmembrane transporter activity 0.4111079392277467 2.0646535834171247 0.0389557893854066 1.0 0.1444654750777615 78 P13073,Q9Y5K8,Q9HD20,P61619,Q96ES6,O43772,Q70HW3,O43808,Q9Y619,Q8WWI5,Q9Y487,P00846,Q15758,P30825,Q9UM00,Q9HC07,P08574,O00400,Q93050,Q13423,Q86VD7,Q96NB2,O75964,P56134 24 +G protein coupled serotonin receptor binding 0.6886149854038276 2.0615066610134 0.0392547286532565 1.0 0.1451784937420709 2 P08754 1 +H4 histone acetyltransferase activity 0.7769575517612306 2.0350176729623675 0.0418490947582563 1.0 0.1526202962117348 3 Q86UY6 1 +Proline rich region binding 0.8611506839832617 2.0208253295532943 0.0432978497824727 1.0 0.1552637884597497 6 Q9UQB8 1 +Metalloexopeptidase activity 0.580217701048876 2.010032401477127 0.0444277596482387 1.0 0.1582884316263166 18 Q9NQH7,P55786,Q7Z2K6,Q969V3 4 +Transporter activity 0.3347204112401234 2.007134170874551 0.0447353786448794 1.0 0.1589682776388535 187 P13073,Q9Y5K8,Q9HD20,P61619,Q96ES6,O43772,P03886,Q70HW3,Q8IXU6,O43808,Q9BSK2,Q9Y619,Q8WWI5,Q9Y487,P00846,Q15758,P41440,Q16718,Q8NE01,O43676,P30825,Q6P4A7,Q9NUT2,Q9UM00,P38435,Q96AA3,Q9HC07,Q8TDW0,P08574,O00400,Q93050,O95182,P98194,Q9BQT8,Q8TB61,O95168,Q13423,Q6N075,O60830,Q9BZF3,Q86VD7,Q9C0H2,P51991,Q03518,Q96NB2,O75964,O96000,Q9Y5P4,P56134,Q9P0J0,O96008 51 +Demethylase activity 0.7786125156614061 2.0018810115328995 0.0452975303379212 1.0 0.1601297111426256 9 Q9Y2K7,Q8NB78,Q9H6W3 3 +Lysine acetylated histone binding 0.7364183079105678 1.9511956516980529 0.0510337760564991 1.0 0.1719231911210281 10 Q15059,Q03164,Q86X55 3 +Proton channel activity 0.7079808924776319 1.9372906584711744 0.0527098235204444 1.0 0.1744472615783816 11 P00846,O75964 2 +Proton transporting atp synthase activity rotational mechanism 0.7079808924776319 1.9372906584711744 0.0527098235204444 1.0 0.1744472615783816 11 P00846,O75964 2 +Dopamine receptor binding 0.7521090201168008 1.925060230548875 0.0542218235520521 1.0 0.1778214502514289 3 Q14344,P50570 2 +Oxidoreductase activity acting on the ch ch group of donors 0.4872619457801537 1.9107304903389983 0.0560392243878697 1.0 0.1816358320097177 32 P11310,Q15392,Q8N4Q0 3 +Protein methyltransferase activity 0.5081695219580896 1.9095928108674252 0.0561856614813307 1.0 0.1816358320097177 27 Q9H7B4,Q03164,Q86X55,O60725,Q96KQ7,Q15047,O96028,Q9H9B1 8 +Inositol phosphate phosphatase activity 0.6565034057735843 1.9008811372067975 0.0573175833156209 1.0 0.1820109942736806 2 Q10713 1 +Threonine type peptidase activity 0.751046586555953 1.8756861407611312 0.0606983900962743 1.0 0.1886084678562313 9 P20618,P28070,P49721,P28074 4 +Ion transmembrane transporter activity 0.3649650461072329 1.83763285106568 0.0661165246513071 1.0 0.1990809514390022 113 P13073,Q9Y5K8,Q9HD20,P61619,Q96ES6,O43772,Q70HW3,O43808,Q9Y619,Q8WWI5,Q9Y487,P00846,Q15758,P41440,P30825,Q6P4A7,Q9UM00,Q9HC07,Q8TDW0,P08574,O00400,Q93050,P98194,Q9BQT8,Q13423,Q6N075,Q86VD7,Q9C0H2,Q96NB2,O75964,P56134 31 +Nad binding 0.492773073314441 1.8295656930679756 0.067314907663893 1.0 0.2013529435836448 28 P30837,O75874,Q13423,P48735 4 +Cyclin dependent protein serine threonine kinase inhibitor activity 0.6396367174829629 1.8155829305621072 0.0694343739856129 1.0 0.2054351804226504 2 P42771 1 +2 oxoglutarate dependent dioxygenase activity 0.6286039746598039 1.7909325883303158 0.0733041133819649 1.0 0.2151480555993887 13 Q6P6C2,Q9H6W3,Q9Y2K7,Q32P28 4 +Bh3 domain binding 0.7178577445165275 1.771756527097763 0.0764349818034846 1.0 0.2224626513681699 3 Q07812 1 +Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.5828377794455482 1.7674127999124338 0.0771591208588415 1.0 0.2234331138061348 15 Q9UQ84 1 +Phosphatidylinositol phosphate phosphatase activity 0.7982263732038741 1.7506521627628402 0.0800058442184568 1.0 0.2297214219015183 5 Q13614,Q9C0I1 2 +Protein demethylase activity 0.7942031708531867 1.7478760199961934 0.0804854980346145 1.0 0.2298482766277837 6 Q8NB78,Q9Y2K7 2 +Cyclic nucleotide dependent protein kinase activity 0.7121998702141441 1.746253423250936 0.0807669253967802 1.0 0.2298482766277837 3 Q13131,P54619 2 +Camp dependent protein kinase activity 0.7121998702141441 1.746253423250936 0.0807669253967802 1.0 0.2298482766277837 3 Q13131,P54619 2 +Threonine type endopeptidase activity 0.7513070658592702 1.7455197717104738 0.0808944338756123 1.0 0.2298482766277837 8 P20618,P28070,P49721,P28074 4 +Nitric oxide synthase binding 0.6227700291923343 1.7296968239037598 0.0836844564661145 1.0 0.2362957370339873 2 P50570 1 +Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor 0.5128381390111065 1.7029236671773915 0.0885823542914141 1.0 0.2457751987909348 21 P30837,P49419 2 +Protein arginine omega n monomethyltransferase activity 0.6172559195588674 1.7014998665070096 0.0888491628685086 1.0 0.2457751987909348 2 O60678 1 +Endoribonuclease activity producing 5 phosphomonoesters 0.5864552417937625 1.6968959142223792 0.0897163406286325 1.0 0.2458986695246611 14 Q9UQ84 1 +Antigen binding 0.7402922081484631 1.696477577635594 0.0897954730005559 1.0 0.2458986695246611 8 Q15392 1 +Neutral amino acid transmembrane transporter activity 0.7870809630661983 1.69320849683038 0.0904157878344611 1.0 0.2463839753453131 4 Q15758 1 +Lim domain binding 0.6156341226078472 1.69319607754541 0.0904181509766246 1.0 0.2463839753453131 2 Q9Y490 1 +Isocitrate dehydrogenase activity 0.781498594230539 1.682278584400498 0.0925148318473163 1.0 0.2503234316982058 5 P48735 1 +Phosphatase activity 0.4189968187326773 1.628881909077113 0.1033380205344465 1.0 0.2679391116695005 43 Q99956,Q8TF05,Q9H0C8,Q9NPH0,Q9C0I1,Q13555,Q13614,Q969T7,Q5TFE4 9 +Phosphoric ester hydrolase activity 0.3911680494071953 1.628795204036752 0.1033563803280586 1.0 0.2679391116695005 53 Q99956,Q8TF05,Q9H0C8,Q9NPH0,Q9C0I1,Q13555,Q13614,P09601,Q969T7,Q5TFE4 10 +Oxidoreductase activity acting on the aldehyde or oxo group of donors 0.488084912702518 1.6133454188468035 0.1066694841469468 1.0 0.2708529252313334 23 P30837,P49419 2 +Peptide antigen binding 0.7590398787424489 1.6023267484912511 0.1090833737006855 1.0 0.2724082047828129 6 Q15392 1 +Nuclear import signal receptor activity 0.6640083180367954 1.6001391050360854 0.1095677275396858 1.0 0.2731166248745648 10 Q92973,Q9UI26,Q96P70,O00410 4 +Ubiquitin like protein conjugating enzyme activity 0.6913717613138677 1.5985983071365522 0.109909886132165 1.0 0.2734686563544361 9 Q9Y3C8,Q9Y385,Q9C0C9,Q16763 4 +Gtpase inhibitor activity 0.7604176588724029 1.5956973136857844 0.1105563886893108 1.0 0.2740751275157596 5 Q13576,O00410,O94813 3 +Anaphase promoting complex binding 0.6765087605450903 1.5843556872708124 0.1131127999216672 1.0 0.2785858339353283 3 Q9HAW4,Q16763 2 +Cyclin dependent protein kinase activity 0.7575762442270909 1.5839957558851971 0.1131946849127381 1.0 0.2785858339353283 5 P11802,P24941,P50750 3 +Rna polymerase ii ctd heptapeptide repeat kinase activity 0.7502577624566049 1.5538256272632989 0.1202260158441077 1.0 0.2896063850687267 5 P50750 1 +Metalloaminopeptidase activity 0.649993496123015 1.5313981297159 0.1256710260581184 1.0 0.297976073981009 10 Q9NQH7,P55786 2 +Aldehyde dehydrogenase nad p plus activity 0.7193256102451138 1.5135661364733357 0.1301359152769623 1.0 0.3048450614319203 7 P49419 1 +Nucleocytoplasmic carrier activity 0.5091967592445104 1.508759372082571 0.1313602867414052 1.0 0.3071844506100558 17 Q9UI26,P52292,P55060,Q9UIA9,O00410,Q96P70,O14980,Q92973,Q9HAV4 9 +Potassium channel regulator activity 0.7377149019453355 1.5020238232448668 0.1330909563777309 1.0 0.3096355412480202 5 Q96PU5,Q99653 2 +Cyclin dependent protein serine threonine kinase regulator activity 0.7291349064259255 1.4665293742135672 0.1425041247858467 1.0 0.32627934224834 5 P42771,P14635,P11802 3 +Collagen binding 0.6631138360463404 1.4660218726295784 0.1426423281688187 1.0 0.32627934224834 9 Q32P28 1 +S adenosylmethionine dependent methyltransferase activity 0.3902392057709016 1.4607438987614645 0.1440857369483725 1.0 0.3290279999777434 47 Q9H7B4,Q03164,Q86X55,O75648,Q7Z2T5,O60725,Q96KQ7,Q15047,O96028,Q9H9B1 10 +Cation channel activity 0.4762081897319517 1.446639280490684 0.1479979786568814 1.0 0.3362691969148842 21 P00846,O75964,P56134,P61619 4 +Protein kinase a binding 0.5413199747467059 1.4346905319005263 0.1513753034399334 1.0 0.3416613399365661 14 Q9H3P7,Q96M27,P10644,P23396,O43823,Q92667,P41240,P17252 8 +Single stranded dna exodeoxyribonuclease activity 0.7208206845087317 1.4320968080005638 0.1521161178666927 1.0 0.342215825347765 5 Q9UQ84 1 +Tap binding 0.7229118050777785 1.4312171984147164 0.1523679759960807 1.0 0.342215825347765 4 Q03519,Q03518 2 +Dicarboxylic acid transmembrane transporter activity 0.6792484332568431 1.4225516675572494 0.1548661635289392 1.0 0.347236982805414 8 Q15758,P41440 2 +Oxidoreductase activity acting on nad p h 0.4162531044195929 1.4037822207444588 0.1603837098509777 1.0 0.3566703089986612 35 O43676,P03886,O95168,Q13423,O96000,Q9UHQ9,O95831,Q9P0J0 8 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.6323815704088243 1.3823514973119693 0.1668638010041143 1.0 0.3668847062465261 3 Q16850,Q15800 2 +Rrna cytosine methyltransferase activity 0.6313745552672921 1.3777270478644166 0.1682875771246397 1.0 0.3676394742642611 3 Q96CB9 1 +C methyltransferase activity 0.6313745552672921 1.3777270478644166 0.1682875771246397 1.0 0.3676394742642611 3 Q96CB9 1 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.5289627864794118 1.3626289488072194 0.1729994805596728 1.0 0.3733719174906543 14 Q15392 1 +G quadruplex rna binding 0.5497891663963588 1.3529238127599017 0.1760799710752567 1.0 0.376208541025784 2 Q06787 1 +Exodeoxyribonuclease activity 0.6131830531659216 1.3502447751267976 0.1769374801482022 1.0 0.3774481355512589 10 Q9UQ84 1 +Actin monomer binding 0.6179326593508365 1.3159728392807928 0.1881831590264675 1.0 0.3945849618633706 3 Q9UHB6 1 +Fk506 binding 0.6892656168229933 1.3012194735697935 0.1931833414607184 1.0 0.4007965361707894 5 Q96AY3,P26885 2 +Macrolide binding 0.6892656168229933 1.3012194735697935 0.1931833414607184 1.0 0.4007965361707894 5 Q96AY3,P26885 2 +Nucleotide transmembrane transporter activity 0.5171161854409901 1.2935638805349134 0.1958161054223297 1.0 0.4031856573067939 14 Q86VD7,O43808,Q9BSK2,O00400,P41440 5 +Bhlh transcription factor binding 0.5355173532273663 1.2787131922129165 0.200998072385824 1.0 0.4107483130887484 2 O60341 1 +Palmitoyltransferase activity 0.679343673729826 1.2692400395340095 0.2043554645535081 1.0 0.4169831892913412 6 P50416 1 +Single stranded dna helicase activity 0.5544753934412147 1.2625070902480484 0.2067663766073688 1.0 0.420641313247577 12 P40938,Q96S55,P25205 3 +Proteasome binding 0.6165242966580704 1.2467953243344072 0.2124725553618547 1.0 0.4296807546025026 9 O95456 1 +Spectrin binding 0.6750481857190256 1.242245387065439 0.2141460384044453 1.0 0.4324224900125373 5 P11171,P35611,Q12955 3 +Cis trans isomerase activity 0.436723351528383 1.2399685102842304 0.2149870416213968 1.0 0.432978906118023 23 O95302,P26885,Q9NWM8 3 +Nucleobase containing compound transmembrane transporter activity 0.4673147145748438 1.2380591729602295 0.2156941207553413 1.0 0.432978906118023 17 Q86VD7,O43808,P51991,Q9BSK2,O00400,P41440 6 +Protein phosphatase regulator activity 0.5476355055186434 1.2260794334982783 0.2201687844886688 1.0 0.4406613466015857 12 Q9NY27,Q8TF05,P30154 3 +Camp dependent protein kinase regulator activity 0.5888615812497621 1.1824663687614787 0.237020702369703 1.0 0.4688738022168109 3 P54619 1 +Amp activated protein kinase activity 0.5883501673662217 1.1801212765154256 0.2379519835093784 1.0 0.4700328730860145 3 Q13131 1 +Bh domain binding 0.6598951461007452 1.1723125430560717 0.2410715975643336 1.0 0.4741306998338989 4 Q07812 1 +Signaling receptor complex adaptor activity 0.6568435488572095 1.1668466888641444 0.2432722882915321 1.0 0.4770800927446328 5 Q96T76 1 +Protein kinase a regulatory subunit binding 0.6348617710374599 1.1474104744143618 0.2512120142062559 1.0 0.4912349875498769 7 Q9H3P7,P17252,O43823,Q96M27 4 +Aminopeptidase activity 0.5111154988988991 1.1391006832858717 0.2546611625547057 1.0 0.4956747992195695 13 Q9NQH7,P55786 2 +Ribosome binding 0.3748627154611876 1.1321584282255523 0.2575678341458238 1.0 0.4993587211858493 39 Q9BXJ9,P61619,P42345,Q9UM00,Q969V3,P46379,Q15070,Q6P1Q0 8 +Passive transmembrane transporter activity 0.3808921586579687 1.1270620185276574 0.2597162604631458 1.0 0.5028077247373278 36 P61619,O75964,Q9UM00,Q8TDW0,P00846,Q9C0H2,P56134,O96008 8 +Trna binding 0.3739282425802804 1.1237841691956996 0.2611045989687341 1.0 0.5035974233748594 39 O43592,Q7Z7L1,O95163,O75648,Q5JPH6,Q9NSE4,Q7Z2T5,P56192,O95363,Q5JTZ9,Q9NX74,Q7L0Y3,Q08J23,Q9HAV4,Q92552,Q9H9T3,P05198 17 +Adp transmembrane transporter activity 0.6462291573060305 1.122993212936946 0.2614403769750595 1.0 0.5035974233748594 5 Q86VD7,O43808 2 +Oxidoreductase activity acting on ch oh group of donors 0.3422949895705562 1.11817999675255 0.2634901257376247 1.0 0.5050845931393061 56 Q9H9P8,P48735,O75874,Q8N4Q0,P56937,Q8N0U8,Q53GQ0 7 +Zinc ion binding 0.3002529597459069 1.1145597622039716 0.2650391213735901 1.0 0.5073393026574629 142 Q8NB78,Q96JM7,Q96T88,Q03164,P55786,Q16629,O43823,Q9NUD5,P62072,Q8N4Q0,P34949,Q15047,Q14527,Q9Y2K7,P14373,Q9ULU4 16 +Importin alpha family protein binding 0.6435182611617497 1.1118106200586009 0.2662195846914561 1.0 0.5081695017742942 5 O14681 1 +Armadillo repeat domain binding 0.6439197791706406 1.106912195570726 0.2683318925714619 1.0 0.5107688192863772 4 O43815 1 +Proton transmembrane transporter activity 0.3739526963769264 1.0963009574432168 0.2729470905440732 1.0 0.5181045888849144 37 P13073,Q9Y5K8,O75964,Q96ES6,Q13423,Q9Y487,P08574,O00400,P00846,P56134 10 +L ascorbic acid binding 0.6389584346112445 1.0930197916516848 0.2743851100905021 1.0 0.5201088228874282 5 Q32P28 1 +Peptidase activity 0.3214303567011601 1.0908736225202262 0.2753284952229842 1.0 0.5211711849770257 105 Q9NP73,Q10713,P52888,Q969V3,P42785,Q9BYT8,Q9BT78,P49721,Q7Z2K6,Q96K76,Q9NZ08,Q9NUQ7,P28074,P55786,Q9H8M7,Q9NQH7,P20618,P61009,O43847,P28070,Q9HB40 21 +Glycolipid mannosyltransferase activity 0.5681375730045466 1.087643100943915 0.2767526954928865 1.0 0.5224138953756151 3 Q9H553,O75340 2 +Calcium ion transmembrane transporter activity 0.4690656593815977 1.084714318372055 0.2780482042092116 1.0 0.5241324181838464 15 Q9UM00,Q9HC07,P61619 3 +Gtpase binding 0.3304248683315158 1.083778162209182 0.2784631699656468 1.0 0.5241886228537279 73 Q9NUQ9,O00410,Q7L576,P16989,Q9BZG1,Q9UI26,P67809,Q9Y4F1,Q96N67,O00471,Q96P70,Q96F07,Q6WKZ4,Q13492,Q92973,Q13576,Q9UJZ1,O95373,P50748,P55196,Q9NVG8 21 +Dynactin binding 0.5658663205710592 1.077283654588677 0.2813535623268959 1.0 0.5274410445274178 3 Q9UNH7,P43034 2 +Low density lipoprotein particle receptor binding 0.5783384908327489 1.068060406399448 0.2854932643594896 1.0 0.5315408109346996 9 Q14696,O95782,Q96CW1,Q13492,O00213,P31689 6 +Lipoprotein particle receptor binding 0.5783384908327489 1.068060406399448 0.2854932643594896 1.0 0.5315408109346996 9 Q14696,O95782,Q96CW1,Q13492,O00213,P31689 6 +Death domain binding 0.6330151908955206 1.062424360690157 0.2880430794986086 1.0 0.5355555071005551 4 Q07812 1 +Low density lipoprotein particle binding 0.5603559766899261 1.052184926909055 0.2927147136262329 1.0 0.542592977402897 3 Q8WTV0 1 +Organophosphate ester transmembrane transporter activity 0.4626604521937712 1.046679515091567 0.2952474147152091 1.0 0.5459670263959233 15 Q86VD7,O43808,Q9BSK2,O00400,P41440 5 +Nucleotidase activity 0.624407558443828 1.0402358861219336 0.2982303228252605 1.0 0.549988440874227 6 Q969T7,Q5TFE4 2 +Transferase activity transferring alkyl or aryl other than methyl groups 0.435434744341905 1.033886270884493 0.301189334007423 1.0 0.5530032318635307 17 P28161,P10620,Q9NR45,Q9Y5Z9,P78417 5 +Dna helicase activity 0.366609433921748 1.0323700721512954 0.3018987863986793 1.0 0.5530032318635307 37 P40938,Q96RR1,Q92900,P49736,P25205,P46063,Q2NKX8,P33993,Q9HCK8,O00571,P49959,Q96S55,Q92878 13 +Microtubule plus end binding 0.5481835471189102 1.0317150258543386 0.3022056362832184 1.0 0.5530032318635307 10 Q03001,Q15555,Q14203,Q13586,Q15691 5 +Ubiquitin like protein ligase activity 0.361212334889563 1.0254697272629 0.3051416023656319 1.0 0.5574466051270135 40 Q96PU5,Q96T88,Q6P2C8,Q96J02,Q14527,P14373,Q9C0C9,Q05086 8 +Cytoskeletal anchor activity 0.6193896654277405 1.0194997452179144 0.3079657740621218 1.0 0.5607178978751642 6 Q9UQB8,Q12955 2 +Rna strand annealing activity 0.6222380456655124 1.0186196429899623 0.3083835751226056 1.0 0.5607178978751642 4 P23588,P51114 2 +Trna guanine methyltransferase activity 0.6207347002362344 1.01820564114512 0.3085802391686245 1.0 0.5607178978751642 5 Q7Z2T5 1 +Purine nucleotide transmembrane transporter activity 0.5244870396575085 1.0052139523965578 0.314793838201773 1.0 0.5697266140859216 11 Q86VD7,Q8TB61,O43808,O00400,P41440 5 +Oxidoreduction driven active transmembrane transporter activity 0.3749672575797937 1.0034276558910602 0.315654565970302 1.0 0.5698697891851768 33 O43676,P13073,P03886,O95168,O96000,Q16718,Q9P0J0 7 +Prenyltransferase activity 0.5495901061746951 1.0033119430819453 0.315710375492743 1.0 0.5698697891851768 3 Q9Y5Z9 1 +Protein arginine n methyltransferase activity 0.6176566049983812 1.0000564022721472 0.3172832132353633 1.0 0.5711696578962056 4 Q86X55,O14744,O60678 3 +Peptide binding 0.3237919400173691 0.9990460476245044 0.3177723851572327 1.0 0.5711696578962056 67 Q15392,P61619,P04439,Q9NZ08,P28161,P55786,O60925,Q03519,Q96CW1,Q8WTV0,O00410,P24390,Q13492,P63010,Q92973,Q9BYT8,O43731,Q03518 18 +Solute proton symporter activity 0.6157272314838371 0.992250493069626 0.3210753468478788 1.0 0.5749783513946883 4 Q96ES6 1 +E box binding 0.5438093393259362 0.9771742806847143 0.3284828785518794 1.0 0.5815963821149897 3 Q13547 1 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.3801991408626874 0.9769035331946674 0.3286169124514526 1.0 0.5815963821149897 29 O43676,P03886,O95168,O96000,Q9P0J0 5 +Atp dependent activity acting on dna 0.3291586082034371 0.9729658234014984 0.3305702883103227 1.0 0.584293717390064 54 P41440,Q14527,P25205,Q96RR1 4 +Syntaxin 1 binding 0.5425048669694978 0.9712875248778676 0.3314051192870249 1.0 0.5847341085081132 3 O00186,O75150 2 +Mhc protein binding 0.5523792756347871 0.9481321107426972 0.3430622030211636 1.0 0.5978331092340636 9 Q9NUQ9,Q03519,Q9BUN8,P07437,Q03518,P51572 6 +Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.3854273808572059 0.943805520973123 0.3452690387986832 1.0 0.6001419690996268 26 Q9BQP7,Q9UQ84,Q9NQT5 3 +Metalloendopeptidase activity 0.4543867367231897 0.9321553599942756 0.3512562415228601 1.0 0.6064545781777154 14 O43847,Q10713,P52888 3 +Adenylyltransferase activity 0.5993968231764806 0.9313831276606152 0.3516554154131825 1.0 0.6064545781777154 5 O43252 1 +Amp binding 0.584164040382648 0.9305029756461612 0.3521107241797274 1.0 0.6064545781777154 7 P54619 1 +Tetrapyrrole binding 0.414445362205448 0.9272743913475832 0.3537840869524091 1.0 0.6064545781777154 18 Q8WUJ1,P08574,P53701,P09601,P30519 5 +Map kinase scaffold activity 0.4674018812844497 0.9272392975377396 0.3538023035070581 1.0 0.6064545781777154 2 P46940 1 +Tau protein binding 0.4532065588719544 0.9254973960326228 0.3547072375741549 1.0 0.6072409438219181 14 Q9NY61,P54652,Q14203,Q13131,Q13492,O95816,Q00535 7 +Gtpase activating protein binding 0.5971885202013594 0.9224580637188836 0.3562896950862231 1.0 0.6091837625783286 5 P36405,P08754,Q14C86 3 +Transferase activity transferring one carbon groups 0.3214455997725476 0.9189142181411752 0.3581404424566057 1.0 0.6108134613827573 60 Q9H7B4,Q03164,Q86X55,O75648,Q7Z2T5,O60725,Q96KQ7,Q15047,O96028,Q9H9B1 10 +Vitamin binding 0.3483259119498497 0.9116805966512644 0.3619368811071428 1.0 0.6142095949960367 40 Q8TD30,P00374,P38435,Q32P28,P13674,A1L0T0,P41440,Q02218 8 +Lys48 specific deubiquitinase activity 0.5951797395654361 0.9096169532674852 0.3630245546761275 1.0 0.6145229090972755 4 Q9H8M7 1 +Exopeptidase activity 0.368784404007682 0.9027995922852614 0.3666322675857225 1.0 0.6175575695348618 30 Q9HB40,P55786,Q969V3,Q9NQH7,Q7Z2K6,P42785 6 +Aminoacyl trna editing activity 0.5183303992255291 0.8884622692709938 0.3742921429208765 1.0 0.6250449159697091 10 P26640,Q5JTZ9,Q9P2J5,Q9NSE4 4 +7s rna binding 0.5721247563353057 0.8798982918336294 0.378914410174948 1.0 0.630338780188226 7 P09132,Q13868,Q9UHB9,P37108,P49458,O76094 6 +Protein serine threonine kinase activator activity 0.5840191046472801 0.8695156368862742 0.3845651590231125 1.0 0.6338729662901195 5 Q9NQS7,P14635 2 +Centromeric dna binding 0.5844607652346188 0.8669397875063698 0.3859750018602892 1.0 0.6352019075354941 4 P43246,Q03188 2 +Nuclear export signal receptor activity 0.5652634137624524 0.8512779656913028 0.3946149619078878 1.0 0.6431987582714196 7 P55060,Q9UIA9,Q9HAV4,O14980 4 +Rna polymerase activity 0.4050593375045732 0.844104275971095 0.3986111385051951 1.0 0.6489351190258021 17 O00411,O15514,O15160,O14802,P19387 5 +L amino acid transmembrane transporter activity 0.5465956363108393 0.8318993705807155 0.405465747167701 1.0 0.6585189521422924 8 P30825,Q15758 2 +Omega peptidase activity 0.3819232752654639 0.823240930540137 0.4103709971593132 1.0 0.6641543426629537 22 P45974,Q9NP73,Q86UV5,Q9H8M7,Q9P275,Q96K76 6 +Ubiquitin like modifier activating enzyme activity 0.5698894619370454 0.8133323907556363 0.4160275109026334 1.0 0.6724625205920239 5 Q13564,Q9UBE0,A0AVT1 3 +Transition metal ion transmembrane transporter activity 0.5661655286950221 0.803367092955324 0.421762589174433 1.0 0.6754260847498559 6 Q9HC07,Q9HD20,P98194,P35670 4 +Endopeptidase activity 0.3111232692608577 0.7957119451868322 0.4261994822675847 1.0 0.6794582373576141 56 P67812,Q9NZ08,P28074,P20618,O43847,Q9P275,Q10713,P52888,Q99436,P49721,P28070,Q96K76,Q9BYT8 13 +Phosphotransferase activity for other substituted phosphate groups 0.5509973964396253 0.7923656732232496 0.4281474887621264 1.0 0.6794582373576141 7 Q9NRN7,Q9BVG9 2 +Mhc class i protein binding 0.537063068501835 0.7911758734098928 0.4288413683871539 1.0 0.6794582373576141 8 P06576,Q03519,Q9BUN8,P07437,Q03518,P51572 6 +Hsp90 protein binding 0.392592826422554 0.7903254383007076 0.4293377343325697 1.0 0.6794582373576141 18 Q9UHD1,P23396,O95801,Q15185,P55011,Q00535 6 +Hydrolase activity hydrolyzing n glycosyl compounds 0.5493968592160892 0.7858114084086366 0.4319779819470675 1.0 0.6828362757606955 7 P23396,Q16706,P29372 3 +Camp binding 0.4989252181428213 0.7779079397855687 0.43662328721611 1.0 0.6885797148332858 3 P10644 1 +Phosphatidylinositol 4 phosphate binding 0.5603438751944343 0.7758024730148121 0.4378656235593907 1.0 0.6889423279356426 5 Q9BZF1,P53367,Q9Y5P4 3 +Growth factor activity 0.5597838537914526 0.770146640117804 0.4412129122166868 1.0 0.6918592550585327 4 Q9UMX5 1 +Phosphatase regulator activity 0.4141496157743866 0.7659989643744777 0.4436769183975766 1.0 0.6925117310561795 15 P30154,P35269,Q8TF05,Q9C0I1,Q9NY27 5 +Transcription coregulator binding 0.3597978730137555 0.7601894792768971 0.4471413327758022 1.0 0.6962921669426394 26 Q71SY5,Q15648,Q9UQB8,Q96KQ7,Q13547,P51858,Q9H582,P50750,Q9H9B1 9 +Peptide transmembrane transporter activity 0.4933616881960435 0.7538157432668171 0.450959869322999 1.0 0.700635139439043 3 Q03518 1 +Monooxygenase activity 0.5278857968232328 0.7524013777613615 0.4518097183027294 1.0 0.7011551044583976 8 P09601,P30519 2 +Transition metal ion binding 0.2669310336198839 0.7464039837578322 0.4554234134794954 1.0 0.7043537110745378 193 Q8NB78,Q96T88,Q03164,O43823,Q8N4Q0,Q15047,Q14527,Q9ULU4,Q9NUD5,P62072,Q32P28,Q9H6W3,P13674,Q9Y2K7,P14373,O75845,Q96JM7,P55786,Q16629,Q9NQH7,O43819,P34949 22 +Atp transmembrane transporter activity 0.5502956691246288 0.7408467663518185 0.4587863556586227 1.0 0.7079458390605278 6 Q86VD7,O43808 2 +Rna cap binding 0.4528426599564538 0.7351395095622808 0.4622545343368713 1.0 0.7124897182700815 12 O15371,Q96C86,Q53F19,Q96F07,Q8TEQ6,Q7L576 6 +Protein tyrosine serine threonine phosphatase activity 0.5441979945019162 0.7171416013176202 0.4732867286783047 1.0 0.7278454663629069 6 Q99956 1 +Amide binding 0.2958741492972305 0.7151667288313135 0.4745060251214994 1.0 0.7280759912803273 98 Q9H3P7,Q15392,P61619,O60925,Q03519,O00410,P41440,Q9BYT8,Q96AY3,P00374,P26885,P04439,Q9NZ08,P55786,P24390,Q13492,Q92973,O43731,Q03518,Q13451,P63010,P28161,Q96CW1,Q9UM22,Q9Y5P4 25 +Polyubiquitin modification dependent protein binding 0.4803399780750535 0.7122819892751041 0.4762901746866905 1.0 0.7299897835006598 10 P35573,P46379,Q9NRR5 3 +Snap receptor activity 0.4041834969190191 0.7107420052840572 0.4772441246658805 1.0 0.7300830911579855 15 O43752,O14653,O95249,P51809 4 +P type calcium transporter activity 0.5435645481934972 0.7079008643380712 0.4790068229382553 1.0 0.7308613071961496 4 P98194,P20020 2 +Cytokine activity 0.5381188924132463 0.6937030302361908 0.4878684652817435 1.0 0.7396773618394454 6 Q92520 1 +Trna methyltransferase activity 0.526485829000097 0.6934204157357291 0.4880457538073637 1.0 0.7396773618394454 7 O75648,Q7Z2T5 2 +Hydrolase activity acting on ester bonds 0.2703130679767135 0.6784478398491078 0.4974877851460066 1.0 0.7506439862347174 162 Q9H6V9,Q96B26,Q99575,Q9NQT5,Q99956,Q8TF05,Q9C0I1,Q9NPH0,Q9UQ84,Q8IY17,P09601,Q969T7,Q9NSE4 13 +Guanyl nucleotide exchange factor activity 0.3435982696482532 0.6658219144000469 0.5055249358850518 1.0 0.7602424726403928 27 P80303,A4D1U4,Q9Y4F1 3 +Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor 0.5188831398052413 0.6634296695625089 0.5070554091028037 1.0 0.7617024412681189 7 Q53GQ0 1 +Microtubule binding 0.2923305664967283 0.661215670153106 0.5084740133173993 1.0 0.7621510265693617 67 Q9UHD1,Q15555,Q96CW5,Q9ULW0,Q00535,O75381,P50570,P29372,Q96SI9,P23396,P60520,Q9BRK0,Q96DB5,Q03001,Q13586,Q9H6D7,Q15691,P07197,P52732,Q99653,O60313 21 +Promoter specific chromatin binding 0.3489068345498129 0.6578295547470004 0.5106476609775066 1.0 0.7637268863630621 24 Q96KQ7,P35269,Q15047 3 +Epidermal growth factor receptor binding 0.5288106102776963 0.6548718536178988 0.5125502633855656 1.0 0.7650145039556528 5 Q92600,O60749,P62993 3 +Exonuclease activity 0.3227822347154447 0.6497339822415105 0.5158640692328391 1.0 0.7677768419793691 36 Q96B26,Q9NQT5,Q13868,Q9BQP7,Q9UQ84,Q9GZR2 6 +Estradiol 17 beta dehydrogenase activity 0.5262041703777519 0.6483782588311772 0.516740328620942 1.0 0.7677768419793691 6 Q53GQ0 1 +Sirna binding 0.4682024659312217 0.6472046497318386 0.5174995024007427 1.0 0.7678960153346467 3 Q06787,Q08211 2 +Hsp70 protein binding 0.391608577274893 0.6426932963152407 0.5204231317258341 1.0 0.7702919458827248 15 P46379,Q8IXB1,Q07812 3 +Ribosomal large subunit binding 0.5209149456020293 0.6285395462247414 0.5296505487914966 1.0 0.7793020507083535 6 P98179 1 +Translation initiation factor activity 0.3285945294864602 0.6190755119925805 0.5358666145672104 1.0 0.781865749028349 31 O15372,Q9Y262,P60228,Q7L2H7,P55010,O15371,O75822,P23588,P06730,P05198 10 +Diacylglycerol binding 0.4028543626337958 0.611677127602152 0.5407513976200193 1.0 0.7871699386982928 2 Q9Y4G8 1 +Isopeptidase activity 0.4919363695009245 0.6055907248189821 0.5447865629657267 1.0 0.7913018762466926 8 O15372,Q9H4L4 2 +Calmodulin binding 0.3238510534963061 0.5972738634026538 0.5503245515069355 1.0 0.7942648086966481 32 P49006,Q9UEY8,O94832,P29966,Q13555,P35611,Q13576,Q5T4S7 8 +Gamma tubulin binding 0.5118945421543232 0.5951419360129065 0.5517485988284496 1.0 0.7954765286075424 6 P07948,O00571,Q96CW5 3 +Monosaccharide binding 0.3389084326112133 0.593810156821786 0.5526390949787245 1.0 0.7959172574243852 24 Q12907,P17858,P49257,Q32P28,Q5KU26,P13674,O60762 7 +Carbohydrate derivative transmembrane transporter activity 0.3892934060339585 0.5824217408896041 0.5602826408923045 1.0 0.8026786044783436 14 P41440,O43808,Q86VD7,O00400 4 +Gpi anchor binding 0.4506813757300562 0.5757007982884251 0.5648174356814977 1.0 0.8073872990367371 3 Q9H490,Q92643 2 +Dna polymerase binding 0.4490399225505114 0.5751912571202216 0.5651619550204958 1.0 0.8073872990367371 10 Q9BXW9,Q9NVI1 2 +Glutathione peroxidase activity 0.483385567951339 0.5721152857715075 0.5672438740570047 1.0 0.8092441431777605 8 P10620,Q8TED1 2 +Nucleotidyltransferase activity 0.307393050687156 0.5672561730544206 0.5705401486529107 1.0 0.8105605695418007 39 Q96BW9,Q9NRG0,O00411,O15514,Q9NR33,O15160,O14802,O43252,Q9NR45,P19387,Q8NFF5 11 +Microtubule minus end binding 0.4981993980943336 0.5432628491600373 0.5869488393401887 1.0 0.8302704558748728 5 Q9H6D7 1 +Channel regulator activity 0.3812078270517697 0.5425019323496424 0.5874727766403398 1.0 0.8302704558748728 14 Q96PU5,Q13586,Q99653 3 +Mrna methyltransferase activity 0.497396538701316 0.5404290055507212 0.5889012090342491 1.0 0.8307994942237145 5 Q8N1G2,Q08J23,Q7L0Y3 3 +Thiol oxidase activity 0.4966399332421969 0.5363084697867138 0.591745377912789 1.0 0.8337116556307513 4 Q6ZRP7 1 +Lamin binding 0.4831940750768086 0.5282515009768446 0.5973247884096231 1.0 0.8372389670705428 7 Q14739,O94901 2 +Ubiquitin like protein transferase activity 0.2816923910134498 0.5272706353934904 0.5980056630285611 1.0 0.8373309746727075 59 Q96PU5,Q96T88,Q96DX4,Q6P2C8,Q96J02,Q14527,Q16763,P14373,Q9C0C9,Q05086 10 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.4921760633981664 0.5242638671102592 0.6000950247344816 1.0 0.8393929379893418 6 Q6ZRP7,Q9UHG3 2 +N acetyltransferase activity 0.3763554748899357 0.5190537644409291 0.6037232492913467 1.0 0.8420990941161866 14 Q86UY6,Q9UKN8 2 +Carboxylic acid binding 0.3102333171864931 0.516160793091635 0.6057421110505119 1.0 0.8420990941161866 33 P28161,P00374,Q13277,Q32P28,O15254,Q9UM22,P13674,P41440 8 +Ligase activity forming carbon sulfur bonds 0.355999980573568 0.5071275309085227 0.6120653389789237 1.0 0.8482901490329074 16 Q9P2R7,P33121 2 +Translation regulator activity 0.2751997796507638 0.5008117255980811 0.6165036326108171 1.0 0.8518390294246924 71 Q9Y262,P60228,Q14011,P06730,Q7L576,P05198,O15372,P63241,P00374,Q96RP9,Q05639,Q7L2H7,P55010,O15371,Q9Y6M1,P23588,Q14232,Q92616,P51114,O00178,P19525,O75822,P62263 23 +Glutathione transferase activity 0.4638375349855236 0.4981480049553887 0.6183797271454072 1.0 0.8535647146499993 8 P10620,P78417 2 +Ribonuclease activity 0.291336296737565 0.4954464356956156 0.620285023361959 1.0 0.8553271700057002 44 Q9NQT5,Q9UQ84,Q99575 3 +Phosphoprotein phosphatase activity 0.3145632694643925 0.4935409209779421 0.6216304332272471 1.0 0.8563147971885459 28 Q99956,Q8TF05,Q13614 3 +General transcription initiation factor activity 0.4827637374648793 0.4915823387562132 0.6230146312153109 1.0 0.856487790993978 6 Q9HBM6,P35269 2 +Structural constituent of cytoskeleton 0.3113546502902682 0.4891265104379597 0.6247521338771902 1.0 0.8575000261626623 29 Q9Y5K6,Q9UEY8,Q96RT1,P07196,Q12955,Q9Y2J2,P07197 7 +Sh3 domain binding 0.3611132084034908 0.4875085413560369 0.6258979913839029 1.0 0.8575000261626623 15 Q9Y5K6,P62993,P50570,Q96D71,O75525 5 +Molecular transducer activity 0.307387782656727 0.4872984500542595 0.6260468459508814 1.0 0.8575000261626623 32 O15031,Q99720,Q15758,Q08722 4 +Heparin binding 0.4441898550386697 0.4860789527741959 0.6269111889167776 1.0 0.8575000261626623 9 Q53GQ0 1 +Protein serine kinase activity 0.2878938385182673 0.4815892189094598 0.6300977863744879 1.0 0.8593184996316594 45 P42345,P31751,O60566,P78362,Q13555,P51812,P24941,O14976,Q96KB5,Q99570,P50750,O14757,P11802,Q13418 14 +Steroid dehydrogenase activity 0.4429965015713705 0.4815511896796274 0.630124807224391 1.0 0.8593184996316594 9 Q53GQ0 1 +Kinase activator activity 0.4580301300992541 0.476931955965907 0.6334105756642587 1.0 0.8620717934790562 8 Q9NQS7,P14635 2 +Peptide n acetyltransferase activity 0.4215900361367877 0.463533080449677 0.6429823088687179 1.0 0.8661165455486626 10 Q9BXJ9,Q86UY6,Q9UKN8 3 +Peptide lysine n acetyltransferase activity 0.438051355546138 0.46297445150884 0.6433826800512108 1.0 0.8661165455486626 9 Q86UY6 1 +Rna 7 methylguanosine cap binding 0.4359597373735241 0.4552093277483602 0.6489586505218996 1.0 0.8705384949771485 9 Q96C86,Q53F19,Q96F07,Q8TEQ6,Q7L576 5 +Non membrane spanning protein tyrosine phosphatase activity 0.366201751540706 0.4501928348981191 0.6525714022492124 1.0 0.8741630693515533 2 P24666 1 +Glycosaminoglycan binding 0.3745298740620924 0.4427240761837095 0.6579653256620253 1.0 0.876929937782897 13 Q53GQ0 1 +Translation factor activity rna binding 0.2766586054473819 0.4422534313507964 0.6583058253572958 1.0 0.876929937782897 49 O15372,Q96RP9,P63241,Q9Y262,P60228,Q05639,Q7L2H7,P55010,O00178,O15371,O75822,P23588,P06730,Q92616,P05198 15 +Metal dependent deubiquitinase activity 0.4587394411956006 0.4422064243961888 0.6583398376004941 1.0 0.876929937782897 7 O15372,Q6P2Q9,Q92905,O00487,O00303,P51665 6 +Transforming growth factor beta receptor binding 0.3639312358092753 0.4408076737692532 0.6593522376244845 1.0 0.876929937782897 2 Q9UNH7 1 +Type i transforming growth factor beta receptor binding 0.3639312358092753 0.4408076737692532 0.6593522376244845 1.0 0.876929937782897 2 Q9UNH7 1 +Nucleoside triphosphatase regulator activity 0.2710003704859173 0.4350890629965297 0.6634977817943191 1.0 0.8801369210741405 56 Q9P2J5,P80303,O00410,O60343,O94813,Q13098,Q92538,Q14344,Q8N6T3,Q9Y2Q5,Q8IZ81,Q9Y4F1,P55010,Q96N67,Q14C86,Q13576,O95373,Q9NPQ8,P46060,A4D1U4,Q9NVG8 21 +Macromolecule transmembrane transporter activity 0.3725177920859278 0.434129108603156 0.6641946887183812 1.0 0.8802034774544467 13 P61619,Q07820,O60830,P51991,O96008 5 +Nadp binding 0.322927789999742 0.4308317379706685 0.6665907206174702 1.0 0.8825194268097051 20 Q13423,Q14739,O75874 3 +Acid thiol ligase activity 0.3988408916314039 0.4276701968110307 0.6688912510715936 1.0 0.8838456239887756 11 Q9P2R7,P33121 2 +N acyltransferase activity 0.3296749678330316 0.422808996465048 0.6724346232825809 1.0 0.8855133220482895 17 Q86UY6,Q9UKN8 2 +Cytokine receptor binding 0.3260777913538994 0.4168823416142051 0.6767644702397451 1.0 0.8869791720077798 18 Q9H2J4,Q9NZ08,Q96J02 3 +Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor 0.4600479015165815 0.4150042535418766 0.6781387893129569 1.0 0.8869791720077798 5 P21953,Q02218 2 +Translation elongation factor activity 0.3678661938771571 0.4145536459393646 0.6784686877206565 1.0 0.8869791720077798 13 Q96RP9,P63241,Q05639,O00178,P43897 5 +Amide transmembrane transporter activity 0.4500447805883292 0.4131643307639011 0.6794862195256239 1.0 0.8869791720077798 7 P41440 1 +Histone binding 0.2684979551907339 0.4129844965169083 0.6796179725295346 1.0 0.8869791720077798 84 Q15059,Q8NB78,Q96JM7,Q96T88,Q03164,Q86X55,Q9BZK7,Q96ES7,Q8WUB8,Q9ULU4,Q96P70,Q15021 12 +Catalytic activity acting on dna 0.2682752963842542 0.4111034892505853 0.6809966515542232 1.0 0.8869791720077798 88 Q96RR1,Q9NRG0,P25205,Q9BQP7,Q14527,Q9UQ84,P41440 7 +G quadruplex dna binding 0.4589602429372801 0.4110465799865999 0.6810383796826818 1.0 0.8869791720077798 4 P36776,Q92878 2 +Cargo adaptor activity 0.4375330445693683 0.4051924288325991 0.6853360698194386 1.0 0.891636270622974 8 O95782,Q96CW1,P63010 3 +Mrna 3 utr au rich region binding 0.3925082118827496 0.4033081772692328 0.6867215268390701 1.0 0.8917586824925803 11 Q96B26,Q01085 2 +Protein serine threonine kinase activity 0.2664684784955357 0.402074346956039 0.6876293114641001 1.0 0.8917586824925803 53 P42345,P31751,P25440,O60566,P54619,P78362,Q13555,P51812,P24941,O14976,Q96KB5,Q99570,P50750,O14757,Q9BUP3,P11802,Q13418 17 +Carbohydrate binding 0.2833035383530168 0.4009058588810962 0.6884894361795952 1.0 0.8917586824925803 39 Q12907,P17858,P49257,Q32P28,Q5KU26,Q16706,P13674,O60762,P35573,Q9NPA0 10 +Misfolded protein binding 0.3484450508421656 0.3927353031409659 0.6945149933145314 1.0 0.8962363917200111 14 P54652,P46379,Q8IXB1 3 +Cytidylyltransferase activity 0.3997232717253378 0.385443812824195 0.6999086273917929 1.0 0.9004060003280284 3 Q9NR45 1 +Electron transfer activity 0.2637100261556158 0.3809470485276475 0.7032425402691402 1.0 0.9029368842512262 54 O43676,P13073,P03886,O95168,O96000,P08574,Q16718,Q9P0J0 8 +Rna polymerase binding 0.2934412023936159 0.3724301455153729 0.7095726127268325 1.0 0.9074701620917974 28 Q6PD62,Q9H7B4,Q92688,Q9P1Y6,Q86U42 5 +Beta catenin binding 0.3262391827658706 0.3665548546500471 0.7139510882923858 1.0 0.9098196921029372 16 Q86X55,Q9BZK7 2 +Four way junction dna binding 0.4338142032451477 0.3613945976375027 0.7178044859634527 1.0 0.9118915182959288 7 P43246,P09429,O15347 3 +Nitric oxide synthase regulator activity 0.3922777417261529 0.3603872303773119 0.7185575746648043 1.0 0.9118915182959288 3 P07900,P23634 2 +Nadph binding 0.4333706781748562 0.360027059642681 0.7188268978878307 1.0 0.9118915182959288 7 Q14739 1 +Rna polymerase ii general transcription initiation factor activity 0.4399592738370144 0.3535306191473537 0.7236906780824353 1.0 0.9123472239213364 5 P35269 1 +Primary active transmembrane transporter activity 0.2592073537747798 0.3519642832378135 0.7248650485736559 1.0 0.9123472239213364 62 O43676,P13073,Q9HD20,Q9NUT2,P03886,O95168,O96000,Q16718,Q9P0J0,Q03518 10 +Nucleotide diphosphatase activity 0.4392640929711757 0.3513610064623176 0.7253175321264669 1.0 0.9123472239213364 4 Q9BW91 1 +Magnesium ion binding 0.2561503397409176 0.3410840533113055 0.7330403058036463 1.0 0.918026469215959 67 Q9P2R7,P48735,O75874,Q9H773,P78362,A1L0T0,A8MXV4,P30520,O60313,Q969T7 10 +Pentosyltransferase activity 0.3341708383403382 0.3346327974502965 0.737902101100657 1.0 0.920517653160398 14 Q13126,P43490 2 +Myosin v binding 0.4328404880207345 0.3328995970742127 0.7392100735986138 1.0 0.9213048627909464 5 Q15907 1 +Protein membrane adaptor activity 0.4143754195454343 0.3307686896432056 0.7408192129031372 1.0 0.921952080031952 8 Q9Y2J2,O94901 2 +Nf kappab binding 0.3462162149389515 0.3292836159763924 0.7419413267985451 1.0 0.921952080031952 13 P09525,O43823,Q13547 3 +Heat shock protein binding 0.2585090470632469 0.3269315308923665 0.7437196721539208 1.0 0.921952080031952 50 Q12907,Q13451,Q8IXB1,Q9UHD1,P54652,P23396,O95801,Q07812,Q6W2J9,Q99615,P46379,Q02218,O95816,P55011,Q00535 15 +Antioxidant activity 0.296098918677703 0.3237867546502891 0.7460994847262126 1.0 0.921952080031952 22 P28161,P10620,Q8TED1,Q6DKJ4,Q9Y5Z9,P78417 6 +Dna n glycosylase activity 0.4288761895110133 0.3216877976934192 0.747689222916261 1.0 0.921952080031952 5 P29372 1 +Protein c terminus binding 0.2648995242807139 0.3191608272914978 0.7496045600463699 1.0 0.921952080031952 44 Q9UQB8 1 +Intramolecular oxidoreductase activity interconverting aldoses and ketoses 0.4279423761443409 0.3190762471824492 0.7496686949957847 1.0 0.921952080031952 5 P34949 1 +Ligase activity 0.2561314020979872 0.3173336251707724 0.7509904656272064 1.0 0.921952080031952 92 Q9P2R7,Q9UKU0,O75964,P33121,Q96J02,O95363,P00846,P56134,P30520,Q9NSE4 10 +Insulin receptor binding 0.4272046782321632 0.3170211776996182 0.7512275329716276 1.0 0.921952080031952 5 O60749,O14654 2 +Signal sequence binding 0.2865010627930808 0.3116600866647786 0.7552988643145837 1.0 0.923152049642862 25 P61619,Q96CW1,O00410,P24390,P63010,Q92973,O43731 7 +Protein domain specific binding 0.2365053469294743 0.3114960085800952 0.7554235767595672 1.0 0.923152049642862 176 Q16625,Q9UQB8,Q96KQ7,Q13547,Q9ULU4,P41440,Q6PD62,O15126,Q9HCM4,Q96K76,P61586,Q9H9B1,O94832,P40616,Q16629,Q9NRX2,Q07812,Q14145,Q9P1Y6,Q9Y5K6,Q14739,Q9Y613,P07196,P54652,P20645,P35269,Q96D71,Q9NQ29 28 +Calcium ion binding 0.2542767699074174 0.3025851827018396 0.7622060079170083 1.0 0.927873324485732 83 O60476,Q96AY3,Q14257,Q86YS7,O95302,Q99653,Q13586,Q9NWM8,Q9UM22,P80303,Q96D71,O43852,O94813,Q9BRK5,Q7L5N7 15 +Rrna adenine methyltransferase activity 0.3734587929915647 0.3007933871137873 0.7635720513444437 1.0 0.9287055959604896 3 Q9UNQ2,Q86W50 2 +Protein transporter activity 0.3083349335420295 0.2930716595584398 0.7694673785373962 1.0 0.9301877850438072 16 O60830,Q9HD20,P61619 3 +Thiamine pyrophosphate binding 0.4168643497679026 0.2891807600766037 0.7724430544037573 1.0 0.9308652800521802 4 A1L0T0 1 +Carboxy lyase activity 0.3292548800995317 0.2698988164393157 0.7872380977425821 1.0 0.9398517991470652 13 P06132,P38435 2 +3 5 exonuclease activity 0.2780673480285826 0.2688143769608758 0.7880725292274942 1.0 0.9400234112871336 24 Q13868,Q9BQ61,Q9GZR2,Q9NQT5 4 +Mrna 3 utr binding 0.2505299136688536 0.2647028028091737 0.7912384181644696 1.0 0.9417495792652036 48 P51114,Q96B26,Q92804,Q14011,Q9NX24,Q01085,Q71RC2,P16989,Q92945,O95453,Q9Y6M1,P35637,Q8TEQ6 13 +Cysteine type peptidase activity 0.2599234880402223 0.2646580735419401 0.7912728784947469 1.0 0.9417495792652036 37 O15372,Q9NUQ7,Q9H4L4,Q9NP73,Q86UV5,Q9H8M7,Q9P275,Q96K76,Q9BT78 9 +Translation repressor activity 0.390819315528336 0.2633041291767903 0.7923161773296512 1.0 0.9417495792652036 8 Q14011 1 +Translation initiation factor binding 0.292115123045457 0.2615463553928249 0.7936712067093175 1.0 0.9417495792652036 17 P62487,O75312,P55010,O15514,O00571,P06730 6 +Tubulin binding 0.245847904368537 0.2495118146564898 0.8029649030731072 1.0 0.9471813980531352 94 Q9UHD1,Q14166,Q15555,Q14203,Q96CW5,Q9ULW0,Q00535,Q9P265,O75381,P50570,P29372,Q96SI9,P23396,P38398,P36405,Q15813,P60520,Q9BRK0,Q96DB5,P50402,Q03001,Q13586,Q9H6D7,Q15691,P07197,Q9HB71,Q9H6H4,P52732,O15344,O00429,Q99653,O60313 32 +C2h2 zinc finger domain binding 0.4003541560872595 0.247623360984493 0.8044258340914952 1.0 0.9471813980531352 4 Q96KQ7 1 +Protein transmembrane transporter activity 0.3341404562242147 0.2468253963152854 0.8050433550433402 1.0 0.9471813980531352 12 Q07820,O60830,P61619,O96008 4 +Atp dependent peptidase activity 0.3996660739310587 0.2455916354390801 0.8059983649151554 1.0 0.9471813980531352 5 P36776,Q96TA2,Q16740 3 +Protein tyrosine phosphatase activity 0.3322824217085855 0.2413087293821101 0.809315845706652 1.0 0.9471813980531352 12 Q99956 1 +Mannosyltransferase activity 0.3901521113569343 0.2401703610294937 0.8101981897737474 1.0 0.9471813980531352 7 Q9BT22,O60762 2 +Transcription coactivator binding 0.396074602842302 0.2371056828512568 0.812574803785266 1.0 0.9481862035978652 6 Q71SY5,P50750 2 +Ribonucleoprotein complex binding 0.2443142747289223 0.2365194579435882 0.8130296102856052 1.0 0.9481862035978652 85 Q9BXJ9,P61619,P42345,Q9UM00,P16989,Q96J02,Q969V3,P46379,Q15070,P57678,Q96E11,P98179,Q6P1Q0 13 +Organic acid binding 0.261825539671493 0.227050209886197 0.8203846996843054 1.0 0.9501335349792744 28 P00374,Q13277,Q32P28,P13674,P41440 5 +Transmembrane transporter binding 0.2605794114243892 0.2105826022890747 0.8332129892535551 1.0 0.9589009160633666 26 Q96PU5 1 +G protein beta gamma subunit complex binding 0.3821473332917042 0.2058222799902684 0.8369297368789803 1.0 0.960254365803393 5 P63096,Q14344,P08754 3 +Protein kinase a catalytic subunit binding 0.3803484159847916 0.2024950647315218 0.8395297162715583 1.0 0.960254365803393 4 P41240 1 +3 5 dna helicase activity 0.3530159498602947 0.2014959909565128 0.8403107639028957 1.0 0.960254365803393 9 P49736,P46063 2 +Mannose binding 0.3790862597376613 0.1992345381527734 0.8420792834162867 1.0 0.9614680408805086 6 Q12907,O60762 2 +Adp binding 0.2654851468469237 0.1892702303304459 0.8498810263554322 1.0 0.9677578249658072 20 Q8NI60,P36776,P35580,Q9Y230,Q9UHD1,P53041,P54619,P00367,Q9UM54,P35579,P43246,Q03518 12 +Polynucleotide adenylyltransferase activity 0.2890042166720761 0.1868844604711566 0.8517512232921318 1.0 0.9677578249658072 2 P51003 1 +1 phosphatidylinositol binding 0.3704521032862494 0.1823740426576726 0.8552891951417205 1.0 0.9684264514042276 4 Q8WTV0,Q13492 2 +Clathrin binding 0.2671504522676883 0.1799460751023125 0.8571949028437706 1.0 0.9684458109283034 17 O95782,Q96CW1,Q13492,O14976,P63010 5 +Transcription corepressor binding 0.2855833591395127 0.1771149958280322 0.8594180631744646 1.0 0.9684458109283034 14 Q96KQ7,Q13547,P51858,Q9H582,Q9H9B1 5 +Non membrane spanning protein tyrosine kinase activity 0.3679441699585239 0.1769890294911383 0.8595170067400364 1.0 0.9684458109283034 5 P07948,P19525,P41240 3 +P53 binding 0.2595538696692085 0.1767197839822068 0.8597285000866322 1.0 0.9684458109283034 21 Q12824,O15164,Q96KQ7,Q13547,Q9HCK8,Q93009,Q9H9B1,Q00535 8 +Oxidoreductase activity acting on peroxide as acceptor 0.2852538890194432 0.1762771469889606 0.8600762149518428 1.0 0.9684458109283034 14 P10620,Q8TED1 2 +Signaling adaptor activity 0.2852491045262076 0.1762650034343782 0.8600857547415635 1.0 0.9684458109283034 14 Q8IZP0,P37198,P46940,P46108,Q7Z434,O60271,Q96T76,P63244,P46109,Q5T2T1,Q9UN86,Q07666,Q13112 13 +Translation regulator activity nucleic acid binding 0.2271617264931035 0.1687879500247388 0.8659634368200957 1.0 0.9732256296549548 57 Q9Y262,P60228,P06730,P05198,O15372,P63241,P00374,P11940,P43897,Q96RP9,Q05639,Q7L2H7,P55010,O15371,P23588,Q14232,Q92616,O00178,O75822 19 +Abc type transporter activity 0.3129374749406188 0.1640056169559252 0.8697267219968416 1.0 0.9755292382666928 11 Q03518,Q9NUT2 2 +C3hc4 type ring finger domain binding 0.3098637248539861 0.1450955831490811 0.8846354055236034 1.0 0.9873814750702976 3 P0DMV9,P31689 2 +Ww domain binding 0.3461229668422179 0.1387582944465806 0.8896411512964673 1.0 0.9884357028034754 5 Q9Y2W2,P50570 2 +Snare binding 0.23525404338197 0.1387284214140022 0.8896647582176762 1.0 0.9884357028034754 27 P51809,O14653,Q13277,O95295,O43752,Q13492,P60520 7 +Oxidized dna binding 0.3426615531392732 0.1331620868048605 0.8940651941083393 1.0 0.9898485943797204 6 P18887,P23396 2 +Protein serine threonine phosphatase activity 0.247975966985319 0.1322494841231189 0.8947869621444011 1.0 0.9898485943797204 17 Q99956,Q9H0C8 2 +Signaling receptor binding 0.2064308252458709 0.1306811684714525 0.8960275299601879 1.0 0.9898485943797204 154 Q14696,P67870,Q9NUQ9,Q3ZCQ8,Q03519,O60749,O94813,O00213,P41440,P31689,Q00535,O75381,Q9BY49,Q14344,Q96RT1,P62993,P50570,Q92990,O15164,O75312,O95782,Q15648,Q9BUN8,Q92520,P43490,Q13740,Q9UMX5,P07942,P60520,O14654,Q9BRK0,Q9H2J4,P53621,P63096,P46939,P04439,Q9NZ08,Q00013,Q03001,P14635,P08754,Q96J02,Q13492,P51858,Q9UJZ1,Q03518,Q9Y5K6,P61981,P28161,Q96CW1,P46379,P17252,P46109,Q96QK1,P51572 55 +Transcription coregulator activity 0.1997906488357893 0.118845494342752 0.9053977648004954 1.0 0.9959373847724554 141 Q9HCD5,Q92804,O75376,Q86X55,Q13547,Q9ULU4,O75381,Q9BZK7,Q9Y2X0,Q9Y2K7,P14373,Q9HBM6,Q05086,Q6P2C8,P61457,O60244,Q99417,Q8WUB8,Q12824 19 +Phosphatidylethanolamine binding 0.3307367737747524 0.1166043200365816 0.9071736141875876 1.0 0.9959373847724554 4 P30086,Q9BSJ8,P50995 3 +Cytoskeletal protein binding 0.1976383732225357 0.1165992260153599 0.9071776510921594 1.0 0.9959373847724554 223 Q9UHD1,Q14166,Q15555,Q96CW5,Q9ULW0,Q7L576,Q00535,Q9P265,O75381,Q6WCQ1,P50570,P29372,P29966,Q96SI9,P23396,P38398,P38435,Q12955,Q9Y2J2,P35611,Q9HCM4,P61586,P60520,Q15907,Q9BRK0,O15145,Q96DB5,P46939,O94832,Q9Y4F1,P50402,P60981,Q14315,Q03001,Q8WXH0,Q13586,Q9H6D7,Q15691,Q13492,Q13576,P07197,P49006,Q9UEY8,Q9NY61,Q9UHB6,Q9H6H4,Q9Y613,P54652,P52732,P55196,Q99653,O60313,O95816 53 +Protein n terminus binding 0.2167053587334925 0.1162802849043863 0.9074304099783972 1.0 0.9959373847724554 42 O75381,Q9UBU8,Q9UJW0,Q9BZK7,Q13547,O00471,Q8IZL8,Q9BRG1 8 +Phosphatidylinositol 3 4 5 trisphosphate binding 0.306841245562179 0.1146828400485687 0.9086965158339848 1.0 0.9959373847724554 9 Q13576,Q92538 2 +G protein coupled receptor binding 0.22695792699081 0.1124657916105191 0.9104540919648108 1.0 0.9968849711698372 24 Q14344,Q96J02,Q9BRK0 3 +Disordered domain specific binding 0.2525580406744164 0.1087610225349336 0.9133920398769686 1.0 0.9988042433387172 14 P54652,Q96CW1,Q14145 3 +Leucine zipper domain binding 0.2865022712524248 0.1070156109906298 0.9147765950970206 1.0 0.9988042433387172 3 Q96IZ0,Q9NY61 2 +Lrr domain binding 0.2865022712524248 0.1070156109906298 0.9147765950970206 1.0 0.9988042433387172 3 Q96IZ0,Q9NY61 2 +Single stranded dna binding 0.2074780163479543 0.1056294751848026 0.91587633775659 1.0 0.9988042433387172 55 P62487,P67809,Q96RR1,P49736,P25205,P46063,P33993,Q9GZR2,Q96B01,Q15631,Q8NFH5,Q9NTJ3,Q96SB8,P43246,Q9Y2W2 15 +Alpha tubulin binding 0.312284201361829 0.0995410977691738 0.9207086586118944 1.0 1.0 7 Q15813,Q9P265 2 +Dipeptidase activity 0.3102888672508984 0.0918752186436757 0.9267971808270494 1.0 1.0 4 Q8IYS1,P12955,Q96KP4 3 +Mrna binding 0.1585599772995939 0.0863281364479083 0.9312055723107406 1.0 1.0 169 Q92804,Q14011,Q01085,Q8IY67,O75153,Q9UN86,Q9Y383,P05198,Q86V81,P00374,P23396,P16989,Q92945,P38159,P67809,Q99729,O15371,Q9Y6M1,Q15631,P51991,O75525,P51114,Q96B26,Q9Y2R9,P35637,Q9NQ29,P62263,O75152,O94913 29 +Guanyl nucleotide binding 0.1838619452209649 0.0785622869040141 0.9373807854756496 1.0 1.0 110 Q6IQ22,P41440,Q9NP72,Q9BUF5,Q14141,Q14344,P63000,P50570,Q969Y2,Q969Q5,O75616,Q9BZG1,P36405,P36404,A4D1E9,P61586,Q15907,Q96RP9,P63096,Q05639,P40616,P08754,P55010,O95140,P20339,P30520,Q8IXI1,Q8N8L6,Q9NTK5,Q9Y6G9,O00178,P62820,O60313,O00429,P36915,Q9Y5M8 36 +Estrogen receptor binding 0.2234926437269453 0.0770090730293029 0.9386163271705406 1.0 1.0 15 O43815,Q96T76 2 +Microfilament motor activity 0.2854811483120844 0.0732497656725721 0.941607365438096 1.0 1.0 7 P35580,O94832,Q9UM54,P35579,P60660 5 +Phosphotransferase activity phosphate group as acceptor 0.2591435911449662 0.0728393822909443 0.9419339316383362 1.0 1.0 10 O75414 1 +Nuclear localization sequence binding 0.2394823894467952 0.0707643011154437 0.943585344151485 1.0 1.0 12 O00410,Q92973 2 +Rna methyltransferase activity 0.2042675221047627 0.0703161309471359 0.9439420436470728 1.0 1.0 21 Q96P11,O75648,Q96CB9,Q7Z2T5,Q08J23 5 +Protein phosphatase 2a binding 0.2663206657585689 0.063550582595804 0.9493280815249998 1.0 1.0 8 O43815 1 +Nucleobase containing compound kinase activity 0.2013320976043177 0.0592772611465482 0.9527312722370342 1.0 1.0 15 P04183,Q5KU26,O75414,Q00013 4 +Histone kinase activity 0.2119140624999994 0.0579341785270784 0.953801058304456 1.0 1.0 13 Q9UIG0,P06493,Q99986,Q16512,Q9Y4B6,P54646,Q13131,O14965,O14757,P24941,P17252,Q96GD4 12 +Beta tubulin binding 0.1976125426039622 0.057188843812868 0.9543947649643392 1.0 1.0 15 O75381,P60520 2 +Actin binding 0.1566757077752013 0.0558950209268221 0.9554254373555496 1.0 1.0 94 Q7L576,Q6WCQ1,P29966,P38435,Q9Y2J2,P35611,O15145,P46939,O94832,P50402,P60981,Q14315,Q03001,Q8WXH0,Q13576,P49006,Q9UEY8,Q9UHB6,Q9Y613,P55196 20 +Pyrophosphate hydrolysis driven proton transmembrane transporter activity 0.2515437114072132 0.0554002592579531 0.9558195892984562 1.0 1.0 8 P61421,Q9Y5K8,P06576,Q9UI12,P38606,P21281,P21283 7 +Atpase coupled ion transmembrane transporter activity 0.2515437114072132 0.0554002592579531 0.9558195892984562 1.0 1.0 8 P61421,Q9Y5K8,P06576,Q9UI12,P38606,P21281,P21283 7 +Actin filament binding 0.1791660352208104 0.0518618505634681 0.9586387721863556 1.0 1.0 64 P49006,Q6WCQ1,P46939,O94832,Q9UEY8,Q9UHB6,Q9Y613,P29966,Q14315,Q8WXH0,P55196,P35611,Q13576,Q7L576,O15145 15 +Vinculin binding 0.2532467532467646 0.0511561602208483 0.9592010851506876 1.0 1.0 5 P12814,Q9Y3I0,P46939,Q9Y490 4 +Helicase activity 0.1530650891740812 0.0497944269269837 0.960286207843712 1.0 1.0 87 P42694,P40938,Q14562,Q9HCE1,Q96RR1,P49736,P25205,P46063,Q2NKX8,Q14527,Q9HCK8,Q7Z7L1,P49959,Q96S55 14 +Supercoiled dna binding 0.2448051948052013 0.047958846750747 0.9617490403783024 1.0 1.0 5 P23396,O75475,P26583,P09429 4 +Amyloid beta binding 0.1941874735908059 0.045707867488851 0.9635430930158108 1.0 1.0 11 O00213,O60925,Q8WTV0,Q13492 4 +Histone threonine kinase activity 0.2360311166872341 0.0457011883753713 0.9635484166141888 1.0 1.0 6 O14757 1 +Retinoic acid receptor binding 0.2222575421725203 0.04531072324199 0.9638596403070212 1.0 1.0 8 Q71SY5 1 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..cdcf8aadb8225e0708a12d52a7b39dbe3722f3d6 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 3 kinase regulator activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5alpha androstane 3beta 17beta diol dehydrogenase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 1 adaptor complex binding", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide 1 phosphate binding", "Ceramide 1 phosphate transfer activity", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Choline transmembrane transporter activity", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromatin insulator sequence binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Copper ion transmembrane transporter activity", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix protein binding", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibronectin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyl n acetylgalactosaminyl proteoglycan 4 beta n acetylgalactosaminyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophosphodiester phosphodiesterase activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanosine diphosphatase activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Icosanoid binding", "Identical protein binding", "Igg binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n acetyltransferase activity acting on acetyl phosphate as donor", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Neuregulin binding", "Neurexin family protein binding", "Neurotransmitter binding", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphate ion transmembrane transporter activity", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphorylation dependent protein binding", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Platelet derived growth factor receptor binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein cysteine s stearoyltransferase activity", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase 2b binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein self association", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp n acetylglucosamine transmembrane transporter activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL8A", "ARL8B", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPIF1", "ATRIP", "ATRX", "ATXN2L", "AUP1", "AURKA", "AURKB", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf35", "C1orf52", "C2CD5", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC22", "CCDC47", "CCDC59", "CCDC6", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA5", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPV", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "COG2", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC19", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLK", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GID8", "GIGYF2", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPI", "GPR107", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS4", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1147", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LETMD1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLPH", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LZIC", "M6PR", "MACF1", "MAEA", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NES", "NFS1", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NKRF", "NKTR", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDZD8", "PEBP1", "PECR", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2B", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PWWP2A", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RTCB", "RTF1", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35A4", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPCS2", "SPCS3", "SPEN", "SPOP", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM29", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKT", "TLE3", "TLN1", "TM7SF2", "TMBIM6", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM165", "TMEM192", "TMEM201", "TMEM43", "TMEM59", "TMEM70", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TST", "TTC1", "TTC26", "TTC4", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBFD1", "UBIAD1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "URB1", "UROD", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VPS16", "VPS25", "VPS33B", "VPS35", "VPS4A", "VRK1", "VRK2", "WARS", "WARS2", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZCCHC17", "ZCCHC3", "ZCCHC8", "ZDHHC20", "ZEB2", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF148", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF644", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AARS2", "AASDHPPT", "AATF", "ABCB8", "ABI1", "ACADM", "ACBD3", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL6", "ACTN1", "ADD1", "ADD3", "ADSS", "AFDN", "AGL", "AIFM1", "AKAP1", "AKAP8", "AKT2", "ALCAM", "ALDH1B1", "ALDH7A1", "ALG1", "ALG13", "ALG2", "ALKBH5", 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fibers 6 19 2.603861233099014 0.0092180070541414 5.233009708737864 17.730582524271846 1.450228655394427 0.2143723456093393 2.356374883616516 2.3878203593303375 1.2019998086948689 0.268108115907532 0.0412996615361356 0.0008441205885139 0.000529997208151 3.755416319191934e-05 0.000499223363328 +Abnormality of the hypothalamus pituitary axis 11 68 2.577520567109092 0.0099511959327056 15.094660194174756 66.98300970873787 -0.1009468439769967 0.713677449316786 7.298973902553911 7.689180563478128 0.6589892099343162 0.2975772286193155 0.2340005312181654 0.1120350108263911 0.4238315076204146 0.1433977957982448 0.3080113043748715 +Neoplasm of the pituitary gland 2 14 2.4868785838155985 0.01288693724054 4.143203883495145 15.342233009708735 0.0508729963328467 0.5121310391938935 2.6959836051445527 2.391705501904948 1.0573475815766205 0.3195105429159078 1.0 0.2107016729382093 0.3807425591652282 0.1171787786101763 0.4326136578456367 +Fibrous tissue neoplasm 3 19 2.4571959781857817 0.0140026275270614 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0.0339054141593151 10.407766990291265 34.48543689320388 -0.3710583198914421 0.6379062698201862 5.456690723730303 3.811362872391798 0.6662685264145559 0.295841317563314 0.1066998501163677 0.0889868259730537 0.2678609328033907 0.1106824524617488 0.2468496793106456 +Abnormal electroretinogram 3 29 2.118789393627328 0.034108269508279 6.859223300970874 32.19417475728155 0.3723226242578533 0.5367764432246882 4.113037214139201 3.1846362137801685 0.9320732781642423 0.3371359118420042 1.0 0.0963497535154777 0.0894510799340423 0.276161453595085 0.7874650965603622 +Motor axonal neuropathy 3 13 2.1147407877907263 0.0344520459828299 4.257281553398058 16.37378640776699 0.3055932101454106 0.6606056588139702 2.440917460083662 2.148852083035663 0.6415167723360936 0.2892196864974227 1.0 0.1389130578490434 0.0361556764775263 0.1746199077901094 0.062735693833808 +Metaphyseal irregularity 3 10 2.111488487933122 0.0347303463844819 3.5145631067961167 10.509708737864075 -0.1110523585818385 0.6356598427074498 2.226774748374454 1.6582839745981648 0.6900152243921592 0.2624545241273794 1.0 1.0 1.0 0.0065049624434193 0.062735693833808 +Abnormal nasal mucosa morphology 2 5 2.1106407550409343 0.0348032018412034 0.9951456310679612 3.029126213592233 0.5238599989093575 0.4513344844257824 0.947646921342256 1.2303311629304916 1.1326671108301385 0.3296055235905867 1.0 0.1093006244161378 0.0015498580582828 0.0199432580741765 0.1103031547014423 +Memory impairment 5 30 2.1104726186838216 0.0348176672353575 9.20631067961165 37.271844660194176 0.6455055455031676 0.5315679983039603 3.950378988895289 4.419054449573657 0.8352402457141732 0.3415020574881957 0.1018169846700026 0.3807425591661329 0.2498296739424394 0.2228247778855616 0.3559809756040814 +Macrogyria 0 5 2.0914640663789723 0.0364864843424004 1.5024271844660195 5.648058252427185 0.9880312678764684 0.314713035809367 1.057793055191099 0.9137148736849272 0.850980571286911 0.2493075505833739 0.023491782758132 0.1006582454154426 0.1933613304033528 0.4198721048864768 0.6688235417040881 +Eeg with burst suppression 1 8 2.088670912686484 0.0367373569520688 2.866504854368932 9.616504854368932 -0.7277941944778 0.4394023434390625 1.8072519549352304 1.863944928526156 0.8195227437556075 0.3009338202449014 0.0245475710798989 0.1049896535105009 0.0206800818926893 0.1075130907868997 0.3114758752213016 +Abnormality of circulating enzyme level 19 96 2.088061079187312 0.036792325348002 21.808252427184467 94.66747572815534 0.3501601752655411 0.6789071568995501 7.327937619925762 9.045119396126708 0.725288106868536 0.3279554467227489 0.0241705019368046 0.0238675471107415 0.001695387512075 4.478071323951632e-05 0.0041485084313757 +Abnormal corpus callosum morphology 62 276 2.08687669428673 0.0368992820945233 51.95388349514563 283.78155339805824 -0.0442403919486197 0.8930822911985062 17.587791150108213 29.48804018736764 0.3335405439074819 0.19539302333426 0.0058955226322597 0.1393117626727611 0.0523811342321063 0.0578651067274614 0.0107435114438123 +Abnormal involuntary eye movements 43 275 2.0836873144485315 0.0371886188681855 55.56553398058252 281.8349514563107 0.2167412196295073 0.785486722581039 18.633227353522756 29.530171205148992 0.6828698686989364 0.3153801331213574 0.007522856077342 0.0116939279880914 0.0408343114075613 0.0456272523209226 0.0232565728314771 +Aplasia hypoplasia of the ribs 4 22 2.0796219085673684 0.0375602258691305 5.803398058252427 22.609223300970875 0.3131910718004021 0.5928486864249073 2.289208136035978 3.5355630658857047 0.7272860147083524 0.2857730228314329 0.0919783900673582 0.3498897642406863 0.5819578341764894 0.1727170115710306 0.4422776211349686 +Abnormal renal tubule morphology 3 21 2.0708297007213776 0.0383747135992347 5.12378640776699 23.57281553398058 0.5344796879802587 0.5091115156098857 3.0444469953961124 3.073064760825049 0.9046179239778558 0.3270470399524735 0.0730146881724998 0.0444222413024675 0.0304335118961749 0.0915163649386154 0.4498917978075742 +Recurrent sinusitis 1 5 2.0591054329442047 0.0394841395040361 1.8203883495145632 5.065533980582524 0.1394784458399675 0.5166478982984708 1.4062177615412113 1.385807554800596 0.9567780157824576 0.2991860115674145 1.0 0.1263420182810564 0.0299460957191466 0.1486468007453543 0.4012581676146953 +Distal arthrogryposis 0 5 2.056993428734366 0.0396868579715525 1.3883495145631068 4.733009708737864 0.1519686049648115 0.4244431219015394 0.905570781853283 0.6908399769064817 1.0957375224178318 0.2710224797540735 0.0107410366228137 0.0470522829573702 0.0930016660897952 0.2191369015278419 0.3946911962196813 +Keratoconjunctivitis 3 8 2.04824236042809 0.0405362576623296 2.3276699029126213 9.567961165048544 0.3066198135368672 0.5403280269018721 1.572491501440906 1.0109798757499866 0.802064137752686 0.2743185917111204 1.0 1.0 1.0 0.1486468007453543 0.0457284836366409 +Subcutaneous nodule 5 16 2.0461197690981305 0.0407445884281854 5.174757281553398 17.716019417475728 0.7715929851765809 0.3892857335439222 2.3624373807533945 1.5246949972287631 1.0645096840549642 0.3076166958299045 1.0 0.2295798469686227 0.4103737017227389 0.1448032950165304 0.0472812156430325 +Blurred vision 1 5 2.03854448267847 0.041495510900789 1.4684466019417477 4.449029126213592 0.7772225957067546 0.3401357669580369 0.986055451759567 0.9450042528934012 1.0938682095756602 0.2939628040587096 0.0203181815952763 0.0036723611473879 0.0143328298354406 0.0773660358903978 0.2376866166417752 +Feeding difficulties 51 342 2.0278495137947585 0.0425756091401865 67.04368932038835 334.47330097087377 -0.1026663991807636 0.8029870477894212 20.474185356212967 34.34147151481165 0.5522579583000026 0.2811098202858643 0.0011004821918265 0.0436749698193029 0.0142415607330838 0.0069061376980134 0.0023662277092223 +Flat face 7 24 2.02772741091168 0.0425880764451975 6.66747572815534 24.08495145631068 0.4902055675682596 0.5473999825637093 3.284800305273881 3.633055728953568 0.8018127166907104 0.315636792407103 0.0810428554278816 0.314211533829163 0.5341815180867175 0.1230506766835602 0.0363389252815046 +Abnormality of the septum pellucidum 14 40 2.003740312321093 0.0450978855787582 8.526699029126213 40.89563106796116 0.3444144169479532 0.6578867555611217 3.7722499501114135 4.8372824292966765 0.6626144836676359 0.3030567488250643 0.1125274282142768 0.4130249240673272 0.2894956923449571 0.2816176105827496 0.0427469612130841 +External ophthalmoplegia 7 18 1.9882077345013829 0.046788719927608 5.0 17.00242718446602 0.5663831977441792 0.4827064568652057 2.377074975025652 3.293490775365303 0.8939003315322738 0.3080856115403083 0.048546111259079 0.1991580424676108 0.3622612502953293 0.0254140783095469 0.0727366020835562 +Skeletal dysplasia 12 39 1.9805244909588355 0.0476446241770092 9.847087378640778 42.45631067961165 0.4246740768550524 0.5844005076424144 4.1773099838416154 5.798018910120849 0.8069396415917074 0.3278424633591593 1.0 0.4649456287210195 0.1301941969243742 0.0003099571209171 0.0041752291198522 +Action tremor 9 57 1.9744059550312945 0.048335601463249 13.143203883495143 54.47572815533981 1.1235280535029035 0.3645421720231636 5.4627047451961745 5.814853194507433 1.1817578847970691 0.3688885139588422 0.0083517618826479 0.0003930723331033 0.0002747347694742 0.0047598111499749 0.0560617138891143 +Intestinal malrotation 2 29 1.9674704920850008 0.0491289945333877 6.257281553398058 28.679611650485437 0.6127942259513237 0.5095271524901815 3.009986676800097 3.361586519317115 0.8389546187977223 0.3221129319461252 0.0969098674403663 0.3654998372428625 0.2318437245510384 0.4040959228227282 0.6821101789376877 +Ambiguous genitalia 5 22 1.9633280179728736 0.0496080718890139 4.87621359223301 21.094660194174757 0.6419151331050246 0.5170922748249285 2.593254362261455 3.0850832203953606 0.7584464446429787 0.3063377806646535 0.0850331895047633 0.3274019772455256 0.552149589688304 0.5991150617982537 0.1059248866079185 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..593bd4f666b69832147232814156c156841c273a --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 4530, + "title": "Average number of proteins per term", + "value": 23.339293598233997 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f79a0c1772b862c4a7901e504656b96ec4e3e82c --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9e641bb6b3f43575871ae9c35aa354b2b34ce736 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1505 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Language impairment 0.3486277821600971 3.64207023042446 0.0002704542601117 0.70633731573254 0.0102264381842996 279 P11310,Q9NZ01,P49419,Q03164,Q15555,Q5BJH7,Q9NP73,Q8WWI5,Q9Y487,Q10713,P00846,Q8NC96,P41440,Q6P4A7,P17480,Q9UBB6,Q9UM00,Q12955,Q9BZK7,Q13868,P51812,O00400,P57678,Q9H9B1,Q05086,Q9NQT5,Q96DX4,Q9NUQ7,O75648,Q6P2C8,Q9NVR5,Q96F07,Q9BUK6,O95831,Q86VD7,Q8N3U4,Q15021,Q8TD30,Q96PU5,Q9UEY8,Q71SY5,Q9C0E8,Q9UP83,O43791,Q15427,Q7LGA3,O95363,Q96D71,Q9BXJ9,Q12824,O96008 51 +Multiple glomerular cysts 0.9925397340252996 3.455078384050626 0.0005501328604009 0.91732083163438 0.0132558609447676 2 P03886 1 +Retinal arterial tortuosity 0.9925397340252996 3.455078384050626 0.0005501328604009 0.91732083163438 0.0132558609447676 2 P03886 1 +Leber optic atrophy 0.9925397340252996 3.455078384050626 0.0005501328604009 0.91732083163438 0.0132558609447676 2 P03886 1 +Low plasma citrulline 0.9925397340252996 3.455078384050626 0.0005501328604009 0.91732083163438 0.0132558609447676 2 P03886 1 +Muscle weakness 0.3266085352746339 3.2668578695128616 0.0010874826279176 0.9927660993467484 0.0211429025942795 288 Q9NPL8,Q99720,P11310,P13073,Q92804,O43772,Q96RR1,P03886,Q70HW3,Q13614,Q8IY17,P00846,Q8NC96,P41440,O43676,O75381,Q13126,O96011,P00374,Q96RL7,Q9BZK7,Q9NWM8,Q9HC07,P57678,Q8NFF5,Q86U42,O15269,Q9P2R7,Q9NQT5,Q9BQT8,Q8WXH0,Q13586,Q9BQP7,Q96F07,Q9BUK6,O95831,Q14739,Q96B26,P07196,O43819,Q96CU9,O96000,O95363,Q9P0J0,Q12824 45 +Median cleft palate 0.9273434965942264 3.1750104168713578 0.0014983112240498 0.9988777724791624 0.0263075575385499 2 Q8N3U4 1 +Hemangiomatosis 0.9250729808627922 3.1650819674929274 0.0015503926810416 0.9991139426665878 0.0266033289587824 2 P48735 1 +Visceral angiomatosis 0.9250729808627922 3.1650819674929274 0.0015503926810416 0.9991139426665878 0.0266033289587824 2 P48735 1 +Lymphangioma 0.9250729808627922 3.1650819674929274 0.0015503926810416 0.9991139426665878 0.0266033289587824 2 P48735 1 +Ambiguous genitalia male 0.8971780733052164 3.042113484879126 0.0023492330668102 0.9999764066509146 0.0348994015110423 2 Q15392 1 +Micromelia 0.7006721538082394 3.0121288943661657 0.0025942241856595 0.9999922444777792 0.0365818978714196 22 Q14739,Q96HY6,Q15392,P48735 4 +Abnormal muscle fiber morphology 0.4896823833907018 2.9218947105243274 0.0034790913052193 0.9999998608569226 0.0439005114558324 67 O43676,Q99720,Q96RR1,P07196,Q8WXH0,P03886,Q96RL7,Q70HW3,Q13586,O75648,Q9BQP7,O60313,Q9BUK6,P00846,O95831,Q86U42 16 +Neoplasm of the tracheobronchial system 0.8631203373337637 2.889446347756097 0.0038592085669442 0.9999999752894512 0.0477656142302112 2 Q14145 1 +Absent septum pellucidum 0.6107376785940019 2.811531508098867 0.0049306261317165 0.9999999998113226 0.0558393409416902 30 Q9NZ01,Q15392,Q9NUQ7,Q9UBB6,P48651,P51571,Q71SY5,Q9NVI1,Q8N3U4,Q96C86,O96028,P53701,Q08J23,Q9H9B1 14 +Aplasia hypoplasia of the proximal phalanges of the hand 0.8430100551410925 2.797963771308344 0.0051425880465494 0.9999999999281204 0.0559377642335499 2 Q9BXW9 1 +Increased serum testosterone level 0.8374959455076219 2.7727040036799036 0.005559266182344 0.9999999999892244 0.0573655485330717 2 O14802 1 +Progressive visual loss 0.6611905524953118 2.757994882429564 0.0058157108375211 0.99999999999665 0.0589807232753788 22 P00846,P03886,Q8IY17 3 +Small anterior fontanelle 0.8290626013623064 2.7339239786848784 0.0062584492093362 0.9999999999995546 0.0620362428927469 2 Q9Y619 1 +Loss of consciousness 0.9415184214663708 2.7332066344440813 0.0062720969635492 0.9999999999995814 0.0620362428927469 3 P11310 1 +Eeg with abnormally slow frequencies 0.6996086874887548 2.6925160089201388 0.0070915130929756 0.99999999999999 0.0659641772303481 17 Q8NC96,P49419,Q05086 3 +Fasting hypoglycemia 0.9276827596327722 2.6765656588197904 0.0074380990133189 0.999999999999998 0.068307381682369 3 O43772 1 +Chondrosarcoma 0.9253731343283558 2.667073755365315 0.007651487815524 0.9999999999999992 0.0693224796086479 3 P48735,Q92804 2 +Limb undergrowth 0.4995670539455714 2.6654172289977165 0.0076892857694721 0.9999999999999992 0.069525877316784 50 Q14739,Q15392,P48735,Q03164,O75874,Q15427,Q96HY6,O15228 8 +Vitritis 0.8121959130716785 2.6558259464693315 0.0079114436330041 0.9999999999999998 0.0708277463587127 2 P53701 1 +Multiple mitochondrial dna deletions 0.8053843658773836 2.624081941521128 0.0086882879823593 1.0 0.0761876116564533 2 Q96RR1 1 +Nocturia 0.8053843658773836 2.624081941521128 0.0086882879823593 1.0 0.0761876116564533 2 Q96RR1 1 +Irritability 0.4585945868731814 2.6238133369588788 0.0086951424340808 1.0 0.0761876116564533 73 Q9P2R7,P49419,O43772,Q96RL7,Q5BJH7,P00846,O95831,Q12824 8 +Metaphyseal cupping 0.9140035404718608 2.620194479073211 0.0087879634761143 1.0 0.0768522674648608 3 O95831 1 +Abnormality of the pituitary gland 0.470085232938548 2.6177596805801904 0.0088509114705255 1.0 0.077105055695155 63 P48735,P51809,Q03164,Q14746,O75874,Q8IY17,Q9BUK6,Q8N3U4,Q12824,Q9NSE4 10 +Ragged red muscle fibers 0.6650710235065904 2.603861233099014 0.0092180070541414 1.0 0.0793870189263512 19 Q96RR1,P03886,Q70HW3,P00846,O95831,Q86U42 6 +Hyperplasia of the maxilla 0.7995458968537124 2.5967787973264342 0.0094102503550068 1.0 0.0804310077512851 2 Q9H7D7 1 +Abnormality of the hypothalamus pituitary axis 0.457018212008621 2.577520567109092 0.0099511959327056 1.0 0.0825204262522171 68 Q9BXW9,P48735,P51809,Q03164,Q14746,O75874,Q8IY17,Q9BUK6,Q8N3U4,Q12824,Q9NSE4 11 +Joint hemorrhage 0.7894907557573703 2.5495527996192835 0.0107861176972101 1.0 0.0854231996365301 2 P38435 1 +Tracheobronchomalacia 0.7807330522218572 2.5082097939948023 0.0121344598096004 1.0 0.0920755493090304 2 Q9H9B1 1 +Dysgenesis of the cerebellar vermis 0.7807330522218563 2.508209793994796 0.0121344598096007 1.0 0.0920755493090304 2 Q10713 1 +Diaphyseal thickening 0.7800843334414447 2.5051395357595085 0.0122403093586749 1.0 0.0925686166858054 2 Q14739 1 +Abnormal b cell subset distribution 0.7797599740512423 2.503604002306508 0.0122935543272117 1.0 0.0926795884248685 2 P17812 1 +Neoplasm of the pituitary gland 0.7273369673040768 2.4868785838155985 0.01288693724054 1.0 0.0944017054392896 14 P48735,Q12824 2 +Pancreatic fibrosis 0.7745702238079691 2.478998799279808 0.0131751749662223 1.0 0.095614475983039 2 Q96J42 1 +Absent brainstem auditory responses 0.8776768332251781 2.46869393526448 0.0135607148600092 1.0 0.0967257581998664 3 Q13724,P07196 2 +Fibrous tissue neoplasm 0.6416679642122566 2.4571959781857817 0.0140026275270614 1.0 0.0980400350812806 19 Q15392,Q96DX4,Q12824 3 +Excessive wrinkling of palmar skin 0.870352127958587 2.4378283033630503 0.0147757902307565 1.0 0.1026600149468211 3 Q9BZK7 1 +Long eyelashes 0.5189627852987746 2.434040194400005 0.0149313369270225 1.0 0.1031081650600793 39 Q03164,Q9UM00,Q13724,O43791,Q9Y619,Q6P2C8,Q96N67,P26640,Q8IY17,Q12824,O94979 11 +Schistocytosis 0.867150736009926 2.4243044032573513 0.015337743128782 1.0 0.1051134287040581 3 P41440 1 +Vascular tortuosity 0.8602605956141398 2.39512867685818 0.0166145333528766 1.0 0.111961605896369 3 P03886 1 +Reduced forced expiratory volume in one second 0.755757379176119 2.3892262008790923 0.0168839034480483 1.0 0.1129750112550355 2 Q96J02 1 +Abnormal stool composition 0.7541355822250962 2.3814447286853206 0.0172448784347691 1.0 0.1142817401814452 2 P06132 1 +Increased fecal porphyrin 0.7541355822250962 2.3814447286853206 0.0172448784347691 1.0 0.1142817401814452 2 P06132 1 +Vertical nystagmus 0.7521894258838748 2.372098076711917 0.0176873950002292 1.0 0.1163757819649798 2 P49959 1 +Increased muscle glycogen content 0.8546443999295632 2.3712775735256373 0.0177267127081666 1.0 0.1163757819649798 3 Q9BUK6 1 +Demyelinating peripheral neuropathy 0.6865906565437981 2.370702651539533 0.0177543080230964 1.0 0.1163757819649798 15 P00846,P03886,P41440 3 +Abnormality of fundus pigmentation 0.8515664851205232 2.3581795924041424 0.0183648058224865 1.0 0.1171611786138064 3 P38435 1 +Hypopigmentation of the fundus 0.8515664851205232 2.3581795924041424 0.0183648058224865 1.0 0.1171611786138064 3 P38435 1 +Cerebral visual impairment 0.4494410397309712 2.3555513114081696 0.0184952424997022 1.0 0.1171611786138064 61 Q9NZ01,Q9NUQ7,Q9UBB6,Q96RR1,Q71SY5,Q9UP83,P03886,Q96CU9,Q96N67,Q5BJH7,O60762,Q9Y5P4,Q8N3U4 13 +Chorioretinal dysplasia 0.849331702936972 2.3486577667897746 0.0188412153934907 1.0 0.1171611786138064 3 P53701 1 +Respiratory distress 0.4755793904961969 2.3482074798203056 0.0188640100440045 1.0 0.1171611786138064 48 P49419,P51571,P03886,Q13724,Q9Y619,O75648,O43819,P00846,P53701,O95831 10 +Aplasia hypoplasia involving the skeleton 0.294255641853383 2.3301732246002085 0.019796997530983 1.0 0.1215181555763595 296 P13073,Q16625,Q15392,Q5JRA6,Q03164,Q6NUQ1,Q15555,Q9Y619,Q9NP73,Q96HY6,O60762,Q9NR45,Q96J42,O75381,Q96AY3,Q9BXW9,P48735,Q99575,O96011,Q9H1A4,Q9UM00,Q9BZK7,P38435,Q32P28,Q96AA3,P46783,P57678,O75845,Q96DX4,P51571,O75648,O60566,Q6P2C8,Q9BUK6,O95831,P53701,Q8N3U4,P83436,O15228,Q96PU5,Q14739,O75874,O43791,Q15427,Q7LGA3,Q13555,Q9Y5P4,Q12824 48 +Migraine 0.5871387958578173 2.318680826628606 0.0204123488949927 1.0 0.1246198658953062 23 Q9NZ08,O96011,Q96RR1,O43791,P03886,Q13586,Q12824 7 +Wide nose 0.5057990447456978 2.318119767510375 0.0204428128754186 1.0 0.1246378766159438 39 Q03164,Q9UM00,Q13724,P53701,Q9BZK7,O60566,P52732,P51812,Q9NR45,P83436,Q12824 11 +Retinal telangiectasia 0.9390579289212174 2.3113303727861028 0.0208146135972129 1.0 0.1262217549555683 5 P03886 1 +Cerebellar cortical atrophy 0.7375932533246742 2.301689768692106 0.0213526735952056 1.0 0.1286271428009064 2 O75845 1 +Episodic respiratory distress 0.8382000461257921 2.3010814233746135 0.0213870291445963 1.0 0.1286630040172927 3 P03886 1 +Slow decrease in visual acuity 0.843330507261462 2.2927691195467688 0.0218613007623924 1.0 0.130574286379553 9 P00846,P03886 2 +Elongated superior cerebellar peduncle 0.735322737593245 2.290688565097467 0.0219814324538949 1.0 0.130848737209125 2 Q10713 1 +Abnormal superior cerebellar peduncle morphology 0.735322737593245 2.290688565097467 0.0219814324538949 1.0 0.130848737209125 2 Q10713 1 +Abnormal conjugate eye movement 0.2943746611892081 2.2716779145652697 0.0231059710760463 1.0 0.136111897236008 305 Q9NPL8,Q99720,Q15392,Q96RR1,Q03164,P03886,Q9Y619,Q8WWI5,Q9Y487,Q10713,Q8IY17,Q9NR45,O43676,O75381,Q9BXW9,Q9H9P8,O96011,Q9UBB6,Q9UM00,Q96RL7,Q9BZK7,P38435,Q13868,P46783,P61586,Q05086,Q9P2R7,Q9NQT5,Q96DX4,P51571,O75648,Q6P2C8,Q96PU5,Q14739,Q9UEY8,Q71SY5,Q9UP83,O43791,O43819,Q96CU9,Q7LGA3,O96000,O95363,O60313,Q9P0J0,Q12824,Q9NSE4 47 +Rigidity 0.4558821750760473 2.2666241070356365 0.0234131981449539 1.0 0.1373857352288098 51 Q15392,Q96RR1,Q9C0E8,Q96CU9,Q96F07,P00846,Q8NC96,Q9BRK0 8 +Severe lactic acidosis 0.8287742101050174 2.260604576237627 0.0237837541242353 1.0 0.1390198789455307 3 Q70HW3 1 +Tibial torsion 0.7288355497891662 2.259184438401973 0.0238719144123624 1.0 0.1393553766597964 2 P26196 1 +Retinal dystrophy 0.4550377445790464 2.2579182119074117 0.0239507589763232 1.0 0.1395292995326012 51 O75381,O96011,Q9NQT5,P52732,P03886,Q15555,P38435,Q13868,Q9NVR5,Q8IY17,P00846,P53701 12 +Generalized hypotonia 0.3019284608011365 2.252660603906878 0.02428055674575 1.0 0.141014002638779 345 P13073,P11310,Q9NZ01,P49419,O43772,Q03164,Q96RR1,Q15555,Q70HW3,Q9Y619,Q5BJH7,Q9NP73,Q9Y487,Q10713,Q8NC96,Q9NR45,Q02218,O43676,O75381,Q6P4A7,Q9UBB6,P00374,Q12955,Q96AA3,Q9HC07,Q8NFF5,Q05086,O75845,Q9P2R7,Q9NQT5,Q96DX4,Q9NUQ7,P51571,Q13724,O75648,O60566,Q96J02,Q96F07,Q9BUK6,O95831,Q86VD7,Q8N3U4,P83436,O15228,Q8TD30,Q71SY5,Q9C0E8,P50416,O43819,Q96CU9,P34949,O95363,Q96D71,Q13555,Q9P0J0,Q12824,Q9NSE4 57 +Impaired distal proprioception 0.8204835293877139 2.2248582620487873 0.0260907547102329 1.0 0.1455555650706344 3 Q96RR1 1 +Abnormal growth hormone level 0.5375015428446561 2.221762234135579 0.026299378220894 1.0 0.1463589475929359 29 Q03164,Q8IY17,Q8N3U4,Q12824,Q9NSE4 5 +Eeg with frontal epileptiform discharges 0.7194291274732402 2.213314438202089 0.0268759748909017 1.0 0.1488363890657518 2 P42356 1 +Rhizomelia 0.7608911808061041 2.1982968326507573 0.027927959976661 1.0 0.152979031069256 11 Q03164,Q15392,O15228 3 +Small epiphyses 0.9136179096735696 2.1958645482861403 0.0281016398806956 1.0 0.1531401867055792 4 O95831,Q9NR45 2 +Decreased circulating gonadotropin concentration 0.9127970026885126 2.192677920250389 0.0283305926492212 1.0 0.1538819960443311 4 Q8IY17 1 +Abnormal corpus striatum morphology 0.6357048847714842 2.1880460936169177 0.0286662449388943 1.0 0.1553326430301333 16 O95831,P00846,O43819 3 +Macrocytic anemia 0.51206205268913 2.1871809440184657 0.0287293174320408 1.0 0.1554884205103287 34 Q6P4A7,P00374,P46783,P41440,O60313 5 +Posterior pharyngeal cleft 0.7135906584495566 2.18473151579985 0.0289085379817197 1.0 0.1562716909990341 2 P29372 1 +Temporal optic disc pallor 0.7129419396691432 2.181550371196422 0.029142733050407 1.0 0.1569757202358429 2 O60313 1 +Morning glory anomaly 0.7129419396691432 2.181550371196422 0.029142733050407 1.0 0.1569757202358429 2 O60313 1 +Long thorax 0.7119688614985384 2.1767766852203945 0.0294972334213099 1.0 0.1586965171003967 2 Q6W2J9 1 +Anterior open bite malocclusion 0.7116445021083379 2.175184931844562 0.0296162608835748 1.0 0.1591478787693878 2 P08754 1 +Abnormal visual field test 0.9031369079864152 2.17112084223448 0.0299220389338139 1.0 0.1592794786958604 5 P00846 1 +Hemianopia 0.8483725620658891 2.170052785785079 0.0300028473514331 1.0 0.1595221813403661 8 P03886 1 +Undetectable light and dark adapted electroretinogram 0.9064778532503792 2.168113351205714 0.0301500632643687 1.0 0.1601169831038575 4 P00846 1 +Aplasia hypoplasia of the extremities 0.3497032392036627 2.1664626505900193 0.0302758509586817 1.0 0.1605967269822348 177 P13073,Q15392,Q5JRA6,Q03164,Q15555,Q9Y619,Q9NP73,Q96HY6,O60762,Q9NR45,Q9BXW9,Q96AY3,P48735,Q99575,Q9H1A4,Q9BZK7,P38435,Q32P28,P46783,P51812,Q68CP9,Q96DX4,O75648,Q6P2C8,O14802,O95831,O15228,Q14739,O75874,Q15427,Q7LGA3,Q13555,Q9Y5P4,Q12824 34 +Progressive inability to walk 0.5866127790929019 2.162587677052238 0.0305729068993092 1.0 0.1616439774876738 20 Q9P2R7,Q96RR1,Q96RL7,O95363,P00846 5 +Limb dystonia 0.6038140582283793 2.1606412728932005 0.0307230606218293 1.0 0.1616439774876738 18 Q99720,Q96RL7,Q5BJH7 3 +Atlantoaxial abnormality 0.8048498333917949 2.157087709864657 0.0309988310331585 1.0 0.1629056897682232 3 Q9NWM8 1 +Progressive hearing impairment 0.695878466621928 2.1551767780948445 0.0311480033781741 1.0 0.163367318180019 13 P03886,Q9NSE4,O96011,Q96RR1 4 +Abnormal neuron morphology 0.5554042416375327 2.1528746742760796 0.0313285293623759 1.0 0.163877872992567 24 Q99720,Q8IY17 2 +Disproportionate short stature 0.5549761749426475 2.1497995419831466 0.0315710744452726 1.0 0.1647660912869643 24 Q15392,Q96DX4,Q03164,Q32P28,Q96HY6,O15228 6 +Chromosomal breakage induced by crosslinking agents 0.8014276443867517 2.142189939696092 0.0321782007318165 1.0 0.1669625032708305 3 P13073,Q9BXW9 2 +Spondyloepimetaphyseal dysplasia 0.8671544995722331 2.140894491013423 0.032282547509721 1.0 0.1671313602503272 7 O95831,Q9NR45,Q96HY6,Q9NSE4 4 +Absent sternal ossification 0.703535517353217 2.1353061379038674 0.0327360118917983 1.0 0.168324783053174 2 Q9Y619 1 +Microtia third degree 0.703535517353217 2.1353061379038674 0.0327360118917983 1.0 0.168324783053174 2 Q9Y619 1 +Abnormal upper motor neuron morphology 0.8067232938823008 2.1291962959432076 0.0332380232391635 1.0 0.1701336104784305 9 Q99720 1 +Hypopituitarism 0.4993989524198632 2.121194782578208 0.0339054141593151 1.0 0.1718026019482076 35 Q03164,Q8IY17,Q8N3U4,Q12824,Q9NSE4 5 +Abnormal electroretinogram 0.5242571893912349 2.118789393627328 0.034108269508279 1.0 0.1720691354846408 29 P00846,Q9P2R7,Q8IY17 3 +Motor axonal neuropathy 0.688310173063615 2.1147407877907263 0.0344520459828299 1.0 0.172187808489268 13 O95831,O15269,Q8IY17 3 +Metaphyseal irregularity 0.7701162304799922 2.111488487933122 0.0347303463844819 1.0 0.172187808489268 10 Q9NR45,Q96HY6,Q9NSE4 3 +Abnormal nasal mucosa morphology 0.8877987730119468 2.1106407550409343 0.0348032018412034 1.0 0.172187808489268 5 Q9NVR5,Q13432 2 +Memory impairment 0.5195789774269061 2.1104726186838216 0.0348176672353575 1.0 0.172187808489268 30 Q9NZ08,Q96RR1,P03886,Q12824,Q9BRK0 5 +Abnormal ossification involving the femoral head and neck 0.7920085867365178 2.1010706338152016 0.0356347662885896 1.0 0.1754624905296859 3 Q14739 1 +Short sternum 0.7905866120507699 2.0948483184858766 0.0361844782907865 1.0 0.1773979292827521 3 O60566 1 +Eeg with burst suppression 0.8294923585543941 2.0886709126864837 0.0367373569520688 1.0 0.1793321411561117 8 P49419 1 +Abnormality of circulating enzyme level 0.4029611798330127 2.088061079187312 0.036792325348002 1.0 0.179349514901492 96 P11310,O43772,Q96RR1,O14653,Q96RL7,Q9NWM8,Q9HC07,Q8NFF5,Q86U42,Q9P2R7,Q8WXH0,Q13586,Q9BQP7,Q9BUK6,O95831,Q86VD7,P83436,P07196,P50416 19 +Abnormal corpus callosum morphology 0.291854041981089 2.08687669428673 0.0368992820945233 1.0 0.179349514901492 276 Q9NZ01,Q9H7D7,P49419,Q15392,O94979,Q03164,P03886,Q15555,P48449,Q5BJH7,P26640,Q10713,Q8NC96,Q9NR45,Q9NP72,Q96J42,Q9BXW9,Q9H9P8,P78318,P17480,Q9UBB6,P29372,Q9UM00,P51812,Q9H553,Q9H9B1,Q05086,Q68CP9,Q96DX4,Q9NUQ7,Q05639,P51571,P80404,Q14746,O75648,Q6P2C8,Q96N67,O60566,Q13724,O15160,O14802,Q96F07,P98175,O95831,P53701,Q08J23,Q8N3U4,P83436,Q8TD30,Q96PU5,P61981,Q96B26,Q71SY5,Q9NVI1,Q9C0E8,P49902,P42345,Q7LGA3,Q96D71,O96028,O60313,Q12824 62 +Abnormal involuntary eye movements 0.2925934909706923 2.0836873144485315 0.0371886188681855 1.0 0.1801758753720649 275 Q9NPL8,Q99720,Q16625,Q15392,O43772,Q96RR1,P03886,Q15555,Q9NP73,Q10713,O60762,Q8IY17,P00846,Q8NC96,P41440,Q9NR45,O43676,O75381,Q9BXW9,Q9H9P8,O96011,Q9BZK7,Q13868,P61586,Q05086,Q9NQT5,O75648,O60566,Q6P2C8,Q96F07,O95831,Q9UEY8,P07196,P52732,O43819,Q96CU9,Q7LGA3,O96000,Q96D71,Q9H6K4,O60313,Q9P0J0,Q9NSE4 43 +Aplasia hypoplasia of the ribs 0.5604472978563076 2.0796219085673684 0.0375602258691305 1.0 0.181587858257376 22 Q03164,Q14739,Q96HY6,Q15427 4 +Abnormal renal tubule morphology 0.5661974351470196 2.0708297007213776 0.0383747135992347 1.0 0.1845408201746637 21 P00846,Q9NQH7,P03886 3 +Abnormal dlco 0.6889393447940304 2.0631167523657683 0.0391015369027569 1.0 0.1866490644567851 2 O95453 1 +Recurrent sinusitis 0.8748000315847739 2.0591054329442047 0.0394841395040361 1.0 0.1874875806638195 5 Q13432 1 +Keratoconjunctivitis 0.8201654066658427 2.04824236042809 0.0405362576623296 1.0 0.1904867709650965 8 Q14739,P06132,Q9NSE4 3 +Subcutaneous nodule 0.6120711773910897 2.0461197690981305 0.0407445884281854 1.0 0.190871753443309 16 P48735,Q9NZ08,O75874,P11802,Q9NSE4 5 +Focal cortical dysplasia 0.684398313331162 2.0405524567362887 0.0412953319422086 1.0 0.1926548441794082 2 P42345 1 +Blurred vision 0.8696316460049063 2.03854448267847 0.041495510900789 1.0 0.193190816424023 5 P03886 1 +Centrocecal scotoma 0.8716721468280608 2.0317297345097214 0.042181023989404 1.0 0.1951787933319717 4 P03886 1 +Feeding difficulties 0.293354078271544 2.0278495137947585 0.0425756091401865 1.0 0.1954475899178182 342 Q9NPL8,Q99720,Q9NZ01,Q15392,P49419,Q03164,P03886,Q9Y619,Q5BJH7,Q9Y487,Q10713,Q8NC96,O43676,O75381,O96011,Q9UBB6,P00374,Q9H1A4,Q9UM00,Q9BZK7,Q96AA3,Q8NFF5,Q05086,Q9P2R7,Q9NQT5,Q9NUQ7,P51571,Q13724,O75648,O60566,Q6P2C8,Q96J02,Q96F07,O95831,P53701,Q8N3U4,P83436,Q8TD30,Q96B26,Q71SY5,Q9UP83,P50416,O43819,O43791,Q96CU9,Q7LGA3,O96000,O95363,Q9BXJ9,O60313,Q12824 51 +Flat face 0.5380635762218064 2.02772741091168 0.0425880764451975 1.0 0.1954475899178182 24 O75381,O96011,Q03164,Q9UM00,Q15555,Q13555,Q9Y487 7 +Dilation of virchow robin spaces 0.6782354849172887 2.0098507341273497 0.0444469892983554 1.0 0.2001439975363321 2 P43034 1 +Abnormal circulating ceruloplasmin concentration 0.7701230108861141 2.0048850702406624 0.0449753351511075 1.0 0.2008456311281397 3 Q14746 1 +Abnormality of the septum pellucidum 0.4677780608696331 2.003740312321093 0.0450978855787582 1.0 0.2008456311281397 40 Q9NZ01,Q15392,Q9NUQ7,Q9UBB6,P48651,P51571,Q71SY5,Q9NVI1,Q8N3U4,Q96C86,O96028,P53701,Q08J23,Q9H9B1 14 +External ophthalmoplegia 0.5768217254185971 1.9882077345013829 0.046788719927608 1.0 0.2061798650506462 18 P50570,Q96RR1,P03886,Q13586,Q9BQP7,P26640,O60313 7 +Skeletal dysplasia 0.4680579368593785 1.9805244909588355 0.0476446241770092 1.0 0.2086985708838977 39 O75381,Q14739,Q99575,O96011,Q96DX4,Q9H1A4,Q15427,Q96HY6,Q9HC07,O95831,Q9NR45,Q9NSE4 12 +Congenital bilateral hip dislocation 0.672072656503404 1.979059426702639 0.0478093158685204 1.0 0.2088487954526495 2 Q02809 1 +Action tremor 0.4198249932842681 1.9744059550312945 0.048335601463249 1.0 0.2103364789899308 57 Q99720,P03886,Q96RL7,O95363,Q8IY17,P00846,Q9NQH7,P41440,Q9BRK0 9 +Intestinal malrotation 0.5049653364945093 1.9674704920850012 0.0491289945333877 1.0 0.2125638445427376 29 Q9NVR5,Q15392 2 +Ambiguous genitalia 0.5437531192653666 1.9633280179728736 0.0496080718890139 1.0 0.2140233958640316 22 Q15392,P51809,O60566,Q96J42,O75845 5 +Patchy changes of bone mineral density 0.7606100682862009 1.9628026373066287 0.0496691112561129 1.0 0.2140828487061766 3 Q14739 1 +Impaired distal vibration sensation 0.8458721798576827 1.95907544558186 0.0501039519192876 1.0 0.2155469156641718 6 Q9BRK0 1 +Metaphyseal dysplasia 0.737756734645252 1.9576036198891051 0.0502765422779305 1.0 0.2160841902457546 10 O95831,Q9HC07,Q99575 3 +Prominent antihelix 0.6668829062601294 1.95306139364661 0.0508123208699102 1.0 0.2177670894424726 2 P98175 1 +Abnormal circulating protein concentration 0.3505297642864916 1.948415213089401 0.0513653009515129 1.0 0.2178633540885155 143 P11310,O43772,Q96RR1,Q9Y487,P41440,O14653,Q96RL7,Q9NWM8,Q9HC07,Q86U42,Q9P2R7,Q14746,Q13586,Q9BQP7,Q9BUK6,O95831,Q86VD7,P83436,P50416,P34949 20 +Primary hypercortisolism 0.6659098280895221 1.9481798643580872 0.0513934452665392 1.0 0.2178633540885155 2 P17252 1 +Adrenocortical abnormality 0.6659098280895221 1.9481798643580872 0.0513934452665392 1.0 0.2178633540885155 2 P17252 1 +Hyperphosphatemia 0.665909828089521 1.94817986435808 0.0513934452665401 1.0 0.2178633540885155 2 Q15813 1 +Abnormal thyroid stimulating hormone level 0.665909828089519 1.9481798643580723 0.0513934452665409 1.0 0.2178633540885155 2 O14654 1 +Mild postnatal growth retardation 0.6659098280895189 1.9481798643580688 0.0513934452665414 1.0 0.2178633540885155 2 Q9Y3E5 1 +Delayed epiphyseal ossification 0.7572782857506244 1.948025566349597 0.0514119040884377 1.0 0.2178633540885155 3 Q96HY6 1 +Impaired proprioception 0.4578884163353814 1.940035787424133 0.0523753407741343 1.0 0.2201982399552502 41 Q96RR1,P07196,P18887,Q96RL7,O43819,Q9Y619,Q13217,O00400,Q9H6K4,P00846,P41440,Q9BRK0 12 +Hypothermia 0.7081933351901367 1.9383502133994155 0.052580510112709 1.0 0.2201982399552502 11 P03886,O43772 2 +Lacticaciduria 0.8405627150441809 1.937538114175004 0.0526795990162125 1.0 0.2201982399552502 6 O96000,P00846,P03886 3 +Intellectual disability progressive 0.7333862482816523 1.9366669150611135 0.052786072525256 1.0 0.2201982399552502 10 O95831,Q9P2R7,Q9H9P8,Q05086 4 +Abnormal urine ph 0.4478271338426339 1.936375114851664 0.0528217750422488 1.0 0.2201982399552502 44 P11310,P48735,O43772,P03886,P00846 5 +Cognitive impairment 0.3462418576006514 1.9354502048678175 0.0529350735786462 1.0 0.2201982399552502 159 Q9NPL8,Q99720,P61619,Q96RR1,Q03164,P03886,Q9Y619,Q9NP73,Q8WWI5,Q9Y487,Q10713,Q8IY17,P00846,Q8NC96,O75381,P17480,O96011,Q96RL7,Q9BRK0,Q6PGP7,Q9NZ08,Q13217,Q96F07,O95831,Q6DKK2,Q9UEY8,P07196,O43819,Q9H6K4,O60313,Q12824,O96008 32 +Narrow iliac wing 0.7536956494743586 1.9321140726883763 0.0533454277512712 1.0 0.2211471453641681 3 Q9NR45 1 +Reduced tendon reflexes 0.3452271298443372 1.9302878911603845 0.0535711765519062 1.0 0.2213211968740658 161 Q99720,P11310,Q96RR1,P03886,Q8IY17,P00846,Q8NC96,P41440,O75381,Q96AY3,O96011,O14653,Q96RL7,P57678,O15269,Q9P2R7,Q9BQT8,Q8WXH0,Q13586,Q9BQP7,Q96F07,Q9BUK6,O95831,P83436,P07196,P50416,O43819,Q9H6K4,Q9NSE4 29 +Basal ganglia gliosis 0.7917011875144763 1.923976394167868 0.0543575424259952 1.0 0.2224387237486525 8 P00846 1 +Stroke like episode 0.8149988477336123 1.9229493050763309 0.0544864167960836 1.0 0.2227648628937356 7 P03886,Q13586 2 +Muscle stiffness 0.5438076373867189 1.9175034390559345 0.055174004492309 1.0 0.2251695859010449 21 P00846,Q15392,Q9BRK0 3 +Hypogonadotropic hypogonadism 0.5223818166415644 1.9135942999314444 0.0556720139495265 1.0 0.2255786258395006 24 P03886,Q8IY17 2 +Cutaneous finger syndactyly 0.6587739215050146 1.912316272464678 0.0558356398932065 1.0 0.2255786258395006 2 Q9Y619 1 +Flat forehead 0.8414374205323834 1.911821905102238 0.0558990411360045 1.0 0.2255786258395006 4 P83436,Q9NSE4 2 +Oromandibular dystonia 0.8363802444155887 1.905338916663104 0.0567360298150361 1.0 0.2270443595955067 5 Q99720 1 +Abnormal subcutaneous fat tissue distribution 0.8395987686270474 1.904488842645026 0.0568465484012494 1.0 0.2272528478113333 4 Q9BZK7 1 +Pendular nystagmus 0.8105500140900807 1.9041668219588344 0.056888461240188 1.0 0.2272528478113333 7 P00846 1 +Postaxial foot polydactyly 0.8358264034550599 1.9031070750350765 0.0570265749543796 1.0 0.2274035075205457 5 Q14739,Q96J42,O75845 3 +Abnormality of the 5th toe 0.8358264034550599 1.9031070750350765 0.0570265749543796 1.0 0.2274035075205457 5 Q14739,Q96J42,O75845 3 +Cardiac conduction abnormality 0.5071486575628112 1.901782647725199 0.0571995757233709 1.0 0.2276925114471621 27 P00846,P03886,O43772 3 +Abnormal circulating fatty acid anion concentration 0.6047656687204415 1.8973442461118064 0.0577825189134562 1.0 0.2294082477457989 15 P11310 1 +Widened subarachnoid space 0.5009563921068858 1.8933549990278653 0.0583106756355076 1.0 0.2313024173632658 28 P03886,P49419 2 +Hypsarrhythmia 0.4123489065182544 1.8923876298165183 0.0584393529812414 1.0 0.2316100341251303 57 P13073,Q9NZ01,P49419,Q9UBB6,Q9NUQ7,Q71SY5,Q96N67,Q96F07,Q8NC96,Q9NSE4 10 +Amelogenesis imperfecta 0.8354510418791221 1.887929745186045 0.0590353826705238 1.0 0.2327504643145981 4 Q9HC07 1 +Response to drugs acting on neuromuscular transmission 0.6535841712617494 1.886162032750436 0.0592731231051435 1.0 0.2330275379914177 2 Q9H553 1 +Single fiber emg abnormality 0.6535841712617494 1.886162032750436 0.0592731231051435 1.0 0.2330275379914177 2 Q9H553 1 +Emg decremental response of compound muscle action potential to repetitive nerve stimulation 0.6535841712617494 1.886162032750436 0.0592731231051435 1.0 0.2330275379914177 2 Q9H553 1 +Metatarsus adductus 0.7211806056369977 1.878013668213928 0.0603792952957937 1.0 0.2359950023209196 10 O96028,Q15392,Q9H7D7 3 +Atrophy degeneration affecting the central nervous system 0.2785553579890684 1.8773639647641736 0.0604682268547698 1.0 0.2361388514242304 299 Q99720,P13073,Q16625,Q9NZ01,P49419,Q92804,Q96RR1,O96008,P03886,Q9Y619,Q5BJH7,Q9NP73,Q15165,Q10713,O60762,Q8IY17,P00846,Q8NC96,Q9NR45,Q9NP72,Q9H9P8,P17480,Q9UBB6,P00374,Q9UM00,Q96RL7,Q9BZK7,Q96AA3,P51812,O00400,Q05086,O75845,Q9P2R7,Q9NQT5,Q9NUQ7,Q14746,Q13724,O75648,Q6P2C8,Q96N67,Q96F07,O95831,P83436,Q96B26,Q71SY5,P07196,Q9UP83,O43819,Q7LGA3,O95363,Q96D71,O60313,Q9NSE4 53 +Hypoproteinemia 0.6500162179695088 1.8681466356657013 0.0617416346694779 1.0 0.238439560999774 2 Q9UJS0 1 +Abnormal circulating citrulline concentration 0.8268692070770456 1.866954288915192 0.0619079715501467 1.0 0.2387819483089009 5 P03886 1 +Abnormal duodenum morphology 0.6415652782250664 1.8619010839700991 0.0626170342425829 1.0 0.2403553798160556 13 Q9BXW9,Q9NVI1,P38398,O60566,O43684,P98175,Q8N3U4,Q9Y2W2 8 +Thick eyebrow 0.433069658151583 1.8616437774824937 0.0626533182942019 1.0 0.2403553798160556 46 Q03164,Q9UM00,Q96N67,P51812,O95831,Q12824,Q9NSE4 7 +Breathing dysregulation 0.7375081116158332 1.8599447010650825 0.062893350100702 1.0 0.2408342146713274 3 O75380,Q10713 2 +No social interaction 0.648070061628281 1.8583084124675544 0.0631252298813065 1.0 0.2413141699260072 2 Q15067 1 +Prenatal maternal abnormality 0.6142826249154683 1.856935543911795 0.0633203249163449 1.0 0.2418558784747409 14 P50416,Q9NVR5,O43772 3 +Fetal distress 0.505543955212247 1.85328862225666 0.0638410010835799 1.0 0.2434341202934487 26 O43676,P49419,P03886,Q96CU9,O96000 5 +Spinal muscular atrophy 0.6388724023209154 1.847184671262917 0.0647203802179392 1.0 0.2455471711786137 13 Q99720 1 +Amyotrophic lateral sclerosis 0.6369147314110345 1.8364766567869455 0.0662871913956435 1.0 0.247348415998571 13 Q99720 1 +Proximal muscle weakness 0.4004826315942159 1.8335009461651233 0.066728107987698 1.0 0.2487887482998123 63 Q99720,P11310,Q13126,Q96RR1,Q9BQT8,P07196,Q13586,Q13614,Q9BUK6,P00846,Q8NFF5,Q86U42 12 +Pituitary adenoma 0.7116094662253736 1.8318393192665736 0.0669753633039511 1.0 0.2490754819047412 10 P48735 1 +Abnormal bronchoalveolar lavage fluid morphology 0.6425559519948089 1.8303894726659264 0.067191720759149 1.0 0.2490822381660761 2 P53621 1 +Dysphagia 0.3428037055965697 1.8260976139056413 0.0678355595783042 1.0 0.2506485194859039 129 Q99720,Q14739,Q9UEY8,P48735,Q96RR1,Q03164,O75874,P03886,O43819,Q96RL7,Q8N3U4,Q9BQP7,Q8WWI5,P00846,P57678,Q86U42,Q05086 17 +Tremor 0.3383151270239951 1.8205200643989217 0.0686798435533102 1.0 0.2526730489044542 163 Q99720,Q96RR1,P03886,Q8IY17,P00846,Q8NC96,P41440,Q6P4A7,O14653,Q96RL7,Q05086,Q9BRK0,Q96F07,Q9BUK6,O95831,Q9NQH7,Q8TD30,Q9C0E8,P07196,O95363 20 +Disproportionate short limb short stature 0.543449693061295 1.8197168622036168 0.068802134080165 1.0 0.2526730489044542 19 Q03164,Q15392,Q32P28,O15228 4 +Decreased cd4 cd8 ratio 0.8181231491202959 1.8185054522309403 0.0689869141514942 1.0 0.2530451183046713 4 Q13432 1 +Abnormal size of pituitary gland 0.8110723401079907 1.8172099816832987 0.0691849671639128 1.0 0.2533612782963018 6 Q12824 1 +Personality changes 0.6585822565955936 1.8152748809919843 0.069481677202924 1.0 0.2536365252238652 12 P03886,Q8IY17 2 +Anomalous trichromacy 0.7273358958740423 1.8143699224096157 0.0696207931487522 1.0 0.2536365252238652 3 Q9H6K4 1 +Tritanomaly 0.7273358958740423 1.8143699224096157 0.0696207931487522 1.0 0.2536365252238652 3 Q9H6K4 1 +Narrow palpebral fissure 0.5487983429911288 1.806808496342459 0.0707921435095717 1.0 0.2563610770969564 18 Q03164,O43791,O75648,Q9BZK7 4 +Hypoplasia of the iris 0.8118510151194155 1.8061018823893853 0.0709024268637008 1.0 0.2563610770969564 5 Q13586,Q7LGA3 2 +Decreased plasma carnitine 0.6313608896356389 1.8060560360133335 0.0709095871087166 1.0 0.2563610770969564 13 P11310 1 +Biconcave vertebral bodies 0.8093374088316134 1.795888987637685 0.072512174199776 1.0 0.258448286308816 5 Q9NR45 1 +Chronic sinusitis 0.8124961862982409 1.7958784092944005 0.0725138569312373 1.0 0.258448286308816 4 Q9NVR5 1 +Weakness of facial musculature 0.4022770386707571 1.7920356137900353 0.0731272613830591 1.0 0.2597026407269964 58 Q96RR1,Q9NP73,Q13614,O75381,O96011,P50570,P51812,Q9H553,Q86U42,Q9P2R7,Q9BQT8,Q14315,Q9BQP7,Q9BUK6,Q86VD7,P07196,O43819,O60313,Q12824 19 +Bulbar signs 0.6783637580053765 1.7887508478999656 0.0736549499848537 1.0 0.2607387241534626 11 Q99720,P03886 2 +Parathyroid adenoma 0.8103396588169588 1.7871962357909073 0.0739057775022824 1.0 0.2607387241534626 4 P48735 1 +Abnormality of the parathyroid morphology 0.8103396588169588 1.7871962357909073 0.0739057775022824 1.0 0.2607387241534626 4 P48735 1 +Neoplasm of the parathyroid gland 0.8103396588169588 1.7871962357909073 0.0739057775022824 1.0 0.2607387241534626 4 P48735 1 +Multifocal epileptiform discharges 0.4967059130176839 1.78642184946943 0.0740309804868968 1.0 0.2607387241534626 26 Q71SY5,Q9NUQ7,P49419,Q9UBB6,Q96N67 5 +Pulmonary edema 0.7207100578090551 1.7845950818062637 0.0743270197499446 1.0 0.2614141300211561 3 Q13724 1 +Abnormal subarachnoid space morphology 0.4752580536113258 1.7826606452651657 0.0746415612991961 1.0 0.2619103583929967 31 P03886,P49419 2 +Psoriasiform dermatitis 0.6325008108984722 1.779315415361001 0.075188065054363 1.0 0.2628101347965004 2 P10321 1 +Coxa vara 0.584676842357617 1.778351711742947 0.0753461082056075 1.0 0.2631594989756376 15 Q96AY3,Q96DX4,Q99575,Q96HY6,Q9Y487,O95831 6 +Broad foot 0.6996110837450414 1.7737430030236931 0.0761056698161375 1.0 0.2655890248252772 10 Q9BZK7 1 +Recurrent viral infections 0.6746396931663096 1.7699642663906097 0.0767330936463466 1.0 0.2660876286498449 11 Q13432 1 +Atrophy degeneration involving the spinal cord 0.7552997724002917 1.7632594394461858 0.0778567428508183 1.0 0.2679459868291248 8 Q96RR1,Q8IY17,P07196 3 +Abnormal caudate nucleus morphology 0.6969670446391911 1.760910313134193 0.0782535841027805 1.0 0.2683487781874304 10 P00846,O43819 2 +Abnormality of epiphysis morphology 0.4032822983319538 1.7591710252159607 0.0785484640748621 1.0 0.2691562346892023 53 O75381,Q14739,Q5JRA6,O96011,Q96DX4,Q6NUQ1,Q9NUQ7,Q9Y619,P38435,Q7LGA3,Q96HY6,Q9HC07,O95831,Q9NR45,O15228 15 +Skin dimple 0.4834138375813073 1.7563689364034007 0.0790254333617956 1.0 0.2700822072821918 28 Q03164,Q9UM00,O43791,Q6DKJ4,P53701,O96028 6 +Nocturnal hypoventilation 0.6279597794356125 1.756182944745471 0.0790571759064429 1.0 0.2700822072821918 2 P61978 1 +Abnormal light and dark adapted electroretinogram 0.7753818852021886 1.7547266544818756 0.0793060745153286 1.0 0.2704048876087981 7 P00846 1 +Abnormal full field electroretinogram 0.7753818852021886 1.7547266544818756 0.0793060745153286 1.0 0.2704048876087981 7 P00846 1 +Moderately reduced visual acuity 0.7131732641142087 1.750644440807939 0.0800071751664519 1.0 0.2721332938175329 3 O60313,P63000 2 +Mandibular aplasia 0.7131593383952155 1.7505816312390672 0.0800180016258176 1.0 0.2721332938175329 3 P53701 1 +Abnormality of the pulmonary veins 0.7517073124311371 1.7472989942949562 0.0805854874602423 1.0 0.2734473844156536 8 Q15392 1 +Aplasia hypoplasia involving the pelvis 0.5456974444808241 1.743636055812829 0.0812225719726194 1.0 0.2749912190104379 17 O95831,Q9NR45,Q96HY6,Q99575 4 +Abnormal speech prosody 0.750722739795058 1.7429218932928776 0.081347259204225 1.0 0.2752076805042116 8 P03886 1 +Abnormality of retinal pigmentation 0.3842412252980092 1.7357498218089964 0.0826080799547157 1.0 0.2784334837759392 71 O75381,Q9BUK6,O96011,P52732,P03886,Q13432,Q15555,Q96CU9,P51812,Q8IY17,P00846,P53701,Q9NP72,Q9P0J0 14 +Irregular epiphyses 0.7970093434332525 1.7334047298153248 0.0830237575109849 1.0 0.2791343816946915 4 Q9NR45 1 +Low anterior hairline 0.3993261107049082 1.731103327663703 0.0834333369710518 1.0 0.2793880064473886 55 Q68CP9,Q9UM00,O43791,Q96N67,P46783,O95831,Q9NR45,Q9NP72,Q8N3U4,P83436,Q12824 11 +Head titubation 0.7695886154970569 1.7299559851450297 0.0836381394515308 1.0 0.2798233173673817 7 Q99720 1 +Sarcoma 0.3998234640939621 1.7288256562837303 0.0838403028644114 1.0 0.2800859675337639 54 Q13126,Q15392,P48735,Q92804,Q96DX4,Q9H1A4,O75874,O60566,P46783,Q12824 10 +Increased circulating prolactin concentration 0.7689042416987091 1.7270271121395144 0.0841627944124374 1.0 0.2809561228359187 7 Q12824,Q9BUK6 2 +Pancreatic cysts 0.791811237614867 1.724467731859872 0.0846234393450178 1.0 0.2820666131286481 5 Q9NQH7 1 +Dicarboxylic aciduria 0.4923695447771877 1.721813311795303 0.0851033423808866 1.0 0.282845297861641 25 P11310,P48735,O43772 3 +Visual field defect 0.4312120074530448 1.7177146297412282 0.0858486795640307 1.0 0.2846958407211269 42 O75381,O96011,P03886,Q15555,Q9H6K4,P00846,Q12824 7 +Megaloblastic anemia 0.7438880079512403 1.7125035632123375 0.0868039085232657 1.0 0.2868277571969522 8 P41440 1 +Abnormal cd4 cd8 ratio 0.7888208258666347 1.7122459217360235 0.0868513579296754 1.0 0.2868277571969522 5 Q13432 1 +Abnormal circulating fatty acid concentration 0.5140541063790751 1.711394508060588 0.0870083103332044 1.0 0.2868277571969522 21 O75381,P11310,O96011,O43772 4 +Hand polydactyly 0.4723899002024792 1.708995031255693 0.0874518698668191 1.0 0.2874590153706961 29 Q9BXW9,Q14739,Q9UM00,Q10713,Q8IY17,O96028,Q96J42,O75845 8 +Distal muscle weakness 0.3915823050938148 1.7064851013691575 0.0879177978974181 1.0 0.2874590153706961 61 Q99720,Q71SY5,Q9BQT8,P07196,Q96RL7,Q13614,Q8IY17,P00846,P41440,O95831,Q86U42,O15269 12 +Abnormal thyroid hormone level 0.6182289977294775 1.7064798600473952 0.0879187729548844 1.0 0.2874590153706961 2 O14654 1 +Functional abnormality of the gastrointestinal tract 0.2841298973593675 1.7059173960693763 0.0880234603673955 1.0 0.2874590153706961 267 Q99720,Q96RR1,Q03164,P03886,Q9Y619,Q8WWI5,P00846,Q8NC96,P48735,P17480,Q9H1A4,P18887,Q96RL7,P57678,Q8NFF5,Q86U42,Q05086,P11802,O15269,Q9H9B1,Q8IZA0,Q6PGP7,Q9NZ08,P51571,Q96J02,Q9BQP7,Q96F07,Q8N3U4,P83436,Q96PU5,Q14739,Q9UEY8,O75874,O43791,O43819,P34949,O95363,Q96D71,O60313,Q9NSE4 40 +Abnormal palmar dermatoglyphics 0.3943670313756818 1.704219218637686 0.0883401400398802 1.0 0.2874590153706961 58 O75381,O96011,Q71SY5,P42345,Q9BZK7,Q96J02,Q6DKJ4,Q9Y487,P51812,O96028,Q8IY17,Q9H9B1,Q15907 13 +Optic neuropathy 0.4898890669459533 1.7032370379239177 0.0885237179717088 1.0 0.2874590153706961 25 O43676,P03886,Q96CU9,O96000,P00846,Q9P0J0 6 +Muscle fiber tubular inclusions 0.7022647986797026 1.701357421361964 0.0888758915155278 1.0 0.2874590153706961 3 Q13586 1 +Pseudoepiphyses 0.7887833619700377 1.7001085732073682 0.089110504981777 1.0 0.2874590153706961 4 P51812 1 +Pseudoepiphyses of the metacarpals 0.7887833619700377 1.7001085732073682 0.089110504981777 1.0 0.2874590153706961 4 P51812 1 +Pseudoepiphyses of hand bones 0.7887833619700377 1.7001085732073682 0.089110504981777 1.0 0.2874590153706961 4 P51812 1 +Bone fracture 0.7825160554459517 1.6996445354485887 0.0891978079480266 1.0 0.2874590153706961 6 Q9H1A4,Q13126 2 +Photoreceptor layer loss on macular oct 0.6166072007784522 1.698178918555352 0.0894739981617398 1.0 0.2874590153706961 2 P04439 1 +Abnormal optical coherence tomography 0.6166072007784522 1.698178918555352 0.0894739981617398 1.0 0.2874590153706961 2 P04439 1 +Motor neuron atrophy 0.5248383666825135 1.6955321722185903 0.0899745124729223 1.0 0.2878207440638506 19 Q99720 1 +Ventricular preexcitation 0.7612489057009706 1.6942280581183446 0.0902219550928626 1.0 0.2878207440638506 7 P03886 1 +Abnormal form of the vertebral bodies 0.3802527913789419 1.691383735738915 0.0907635365655963 1.0 0.2887673048865625 82 Q5JRA6,Q6NUQ1,Q9Y619,Q96HY6,Q10713,Q9NR45,Q96AY3,P48735,Q99575,Q9UM00,Q32P28,P51812,O75845,Q96DX4,Q9NUQ7,Q96J02,O95831,Q8N3U4,O15228,Q14739,O75874,Q15427 22 +Neonatal hyperbilirubinemia 0.699870214146655 1.690515635229599 0.0909293495889875 1.0 0.2887673048865625 3 P11171,P36551 2 +Macrodontia of permanent maxillary central incisor 0.6982646995269727 1.6832420791440337 0.0923282379499799 1.0 0.2916645173733674 3 O95363 1 +Mitochondrial respiratory chain defects 0.7773068549461941 1.6780983348692355 0.0933279037647607 1.0 0.2936869386440978 6 P03886 1 +Generalized limb muscle atrophy 0.7361493336115066 1.6779946974626772 0.0933481341748998 1.0 0.2936869386440978 8 Q8IY17 1 +Abnormality of hindbrain morphology 0.2745045267297338 1.6761928601230416 0.0937004222685247 1.0 0.2941428496854792 278 Q8NFH4,Q99720,P13073,Q16625,Q9H7D7,Q9UHD1,Q96RR1,Q5BJH7,Q8WWI5,Q9Y487,Q10713,O60762,Q8IY17,P00846,P41440,Q9NP72,Q96J42,Q9H9P8,P17480,P00374,Q9UM00,P18887,Q9BZK7,Q13868,P51812,O00400,Q9H9B1,O75845,Q68CP9,Q9NQT5,O75648,O60566,Q6P2C8,Q96N67,Q13217,Q9BQP7,O15160,O14802,O96028,Q96F07,Q9BUK6,Q8N3U4,P83436,Q6DKK2,Q96B26,Q9C0E8,Q9UP83,Q96CU9,P49959,O95363,Q96D71,Q9H6K4,Q99653,O60313,Q12824 55 +Metaphyseal striations 0.7788637044571993 1.671480931404353 0.0946267220634951 1.0 0.2950165526136495 5 Q9H1A4,Q13126,Q9H7D7 3 +Porokeratosis 0.6937505154145676 1.6627727379249295 0.0963579357054227 1.0 0.2987689587580868 3 Q9H1A4 1 +Polydactyly 0.4248987113792226 1.6579963617373938 0.0973182007254953 1.0 0.3003582409847629 42 Q9BXW9,Q14739,Q9UM00,Q8IY17,Q8N3U4,Q96J42,O75845 7 +Titubation 0.7039693906875376 1.6574700610197 0.0974244769635266 1.0 0.3003582409847629 9 Q99720 1 +Abnormal astrocyte morphology 0.5642904907462448 1.6567167558650169 0.0975767537462775 1.0 0.3003582409847629 15 P00846,O95831,P48735 3 +Skin nodule 0.5114259318196265 1.6544555559957406 0.0980349864424749 1.0 0.3003582409847629 20 P48735,Q9NZ08,O75874,P11802,Q9NSE4 5 +Lateral clavicle hook 0.6916956774823179 1.6534463413928044 0.0982400581143916 1.0 0.3003582409847629 3 Q9Y619 1 +Abnormality of muscle size 0.3161657101137824 1.6509338673766996 0.098752079422854 1.0 0.3012186334466118 191 Q9NPL8,Q99720,P11310,Q92804,Q15165,Q9Y487,Q10713,Q13614,Q8IY17,Q02218,Q6P4A7,Q13126,Q99575,Q96RL7,Q9NWM8,P51812,O00400,Q05086,O15269,Q9P2R7,Q9NQT5,Q9BQT8,Q8WXH0,O75648,Q13586,Q9BQP7,Q9BUK6,O95831,P83436,Q96B26,Q71SY5,P07196,P50416,O43819,Q7LGA3,O95363,Q99653,O60313,Q12824 39 +Vitreous floaters 0.6910351220494702 1.6504470935410602 0.0988515258168578 1.0 0.3012186334466118 3 P04439 1 +Dyspnea 0.3702070772523191 1.6503232226262226 0.0988768450187884 1.0 0.3012186334466118 96 P11310,P49419,Q92804,P51571,P03886,O43819,Q9BZK7,P00846,O95831 9 +Skeletal muscle atrophy 0.3305740307844399 1.6444425356941847 0.1000848249932171 1.0 0.3034700516862608 156 Q9NPL8,Q99720,P11310,Q92804,Q13614,Q8IY17,Q02218,Q6P4A7,Q13126,Q96RL7,Q9NWM8,O15269,Q9P2R7,Q9NQT5,Q9BQT8,Q8WXH0,Q13586,Q9BQP7,Q9BUK6,O95831,P83436,Q96B26,Q71SY5,P07196,P50416,O43819,O95363,Q99653 28 +Positive romberg sign 0.7009725363946311 1.6434806253155998 0.1002835307574132 1.0 0.3035774901120032 9 P07196,Q96RR1,P18887,Q9H6K4,P41440 5 +Impaired adp induced platelet aggregation 0.6052546221213084 1.639943173226764 0.1010169830459777 1.0 0.3053180879993026 2 O00203 1 +Hemifacial spasm 0.7728669000527766 1.635478647711626 0.1019487472207023 1.0 0.3071987051864431 4 Q12824 1 +Lambdoidal craniosynostosis 0.6042815439506961 1.6349414323620108 0.1020613258345743 1.0 0.3071987051864431 2 P61978 1 +Elbow ankylosis 0.6042815439506891 1.6349414323619749 0.1020613258345819 1.0 0.3071987051864431 2 P48651 1 +Humeroradial synostosis 0.6042815439506891 1.6349414323619749 0.1020613258345819 1.0 0.3071987051864431 2 P48651 1 +Abnormal epiphyseal ossification 0.5755276775877219 1.6336528966287756 0.1023317541117754 1.0 0.3071987051864431 14 Q14739,Q96HY6,O75381,P38435 4 +Fibroadenoma of the breast 0.6033084657800825 1.6299381609446868 0.1031145673023083 1.0 0.3090823442530222 2 P10644 1 +Lymphocytosis 0.6033084657800806 1.6299381609446784 0.1031145673023101 1.0 0.3090823442530222 2 Q03252 1 +Pigmentary retinopathy 0.4070176658197879 1.6297047722476183 0.1031639082804789 1.0 0.3090823442530222 47 P03886,Q15555,Q8IY17,Q9BUK6,P00846,Q9P0J0 6 +Goiter 0.6973323095572358 1.6264744991608564 0.103848753868371 1.0 0.3105180561212677 9 O75874,P48735,Q96RR1 3 +Generalized hirsutism 0.4892434563781596 1.6217556420016193 0.1048556796702127 1.0 0.3119578688710853 23 Q03164,Q9P2R7 2 +Cachexia 0.5425985572179637 1.6200926683565822 0.1052123721137157 1.0 0.312327683928658 16 Q99720,P11310 2 +Molar tooth sign on mri 0.6839714471122665 1.6183404635491774 0.1055892449683577 1.0 0.3132411785898236 3 P36405,Q10713 2 +Abnormal brain lactate level by mrs 0.6954889794598385 1.6178575522007443 0.1056932999632715 1.0 0.313344665467029 9 P03886 1 +Red green dyschromatopsia 0.6816133623530876 1.6076087794796063 0.1079208881855815 1.0 0.3180752267278363 3 Q9H6K4 1 +Abnormality of neutrophil morphology 0.7597883457075293 1.6054375772041196 0.1083975403137231 1.0 0.3190556317592992 6 Q14739,P41440 2 +Optic disc coloboma 0.7654145341690722 1.6051316813316403 0.1084648284568037 1.0 0.3190556317592992 4 Q10713,P78318 2 +Tongue atrophy 0.7645569357257485 1.6016361438793576 0.1092360933471596 1.0 0.3206996130023547 4 Q9NQT5 1 +Type i transferrin isoform profile 0.6403162487524721 1.595846280699054 0.1105231175701431 1.0 0.3221812886697222 11 P51571,P34949,Q9NP73,O60762,Q9BT22 5 +Epileptic spasm 0.3817300985423471 1.594738398199211 0.1107707475751422 1.0 0.3226342645429228 61 P13073,Q9NZ01,P49419,Q9UBB6,Q9NUQ7,Q71SY5,P03886,Q96N67,Q9NP73,P00846 10 +Hyporeflexia 0.3471166290535525 1.5945140219368856 0.1108209526774366 1.0 0.3226342645429228 114 Q99720,Q9P2R7,Q9BUK6,Q96RR1,P03886,Q96RL7,Q13586,P57678,Q9BQP7,Q96F07,Q8IY17,P00846,Q8NC96,P41440,O95831,P83436,Q9NSE4 17 +Mitochondrial inheritance 0.7596064903029254 1.5923574590640333 0.1113044091024417 1.0 0.3236399270073911 5 P03886 1 +Abnormality of the mitochondrion 0.3643498694645852 1.592335800593868 0.1113092729089437 1.0 0.3236399270073911 98 O43676,Q9P2R7,P11310,P13073,O43772,Q96RR1,P03886,Q70HW3,Q96CU9,Q9BQP7,O96000,P00846,Q9P0J0 13 +Rod cone dystrophy 0.4253615071966776 1.5916930925580708 0.1114536811405182 1.0 0.3238519407097804 39 O75381,O96011,P03886,Q15555,P38435,Q9NVR5,P00846 7 +Nyctalopia 0.4542939600026583 1.5865074986315155 0.1126242324748489 1.0 0.3253028507366339 30 O75381,O96011,Q15555,Q13432,P38435,Q13586 6 +Progressive sensorineural hearing impairment 0.6877472087814702 1.5816297926424348 0.1137341086238667 1.0 0.3271209600419787 9 P03886,Q9NSE4 2 +Broad nasal tip 0.3871861813928196 1.580678650222273 0.1139515323658708 1.0 0.3275383512800729 52 P52732,Q9BZK7,Q96N67,Q9NP73,Q13868,Q7LGA3,Q9Y487,P51812,O95831,Q12824 10 +Head tremor 0.5663257137007888 1.58025634467247 0.1140481729720721 1.0 0.3276082584422872 14 Q99720,Q96RL7 2 +Pyridoxine responsive sideroblastic anemia 0.7576864197542417 1.573608867707402 0.1155779018892504 1.0 0.3301184713482373 4 Q9BXW9,Q9NVI1 2 +Duodenal stenosis 0.7576864197542417 1.573608867707402 0.1155779018892504 1.0 0.3301184713482373 4 Q9BXW9,Q9NVI1 2 +Abnormal paranasal sinus morphology 0.4881547244511828 1.570114983813217 0.1163883632759332 1.0 0.3309725584682848 22 Q9NVR5,Q13432,Q03518 3 +Sensorimotor neuropathy 0.4492176703584148 1.5693067110158594 0.1165764893297165 1.0 0.3310918474380037 31 P07196,P18887,P03886,Q13217,O60313,P00846,P41440,O95831,Q9NSE4 9 +Extramedullary hematopoiesis 0.7563156730642906 1.5680122996607064 0.1168782619275026 1.0 0.3313257362525574 4 Q14739,Q9NRW7 2 +Mania 0.5877599668613593 1.5653576824180275 0.1174990649902623 1.0 0.3320466403031118 13 P03886 1 +Eeg with multifocal slow activity 0.710700804772356 1.5640654118081725 0.1178022077194613 1.0 0.3322814451862764 8 Q8NC96 1 +Abnormal sputum 0.7496960352727157 1.563450824070523 0.1179465937733579 1.0 0.3324816862435042 6 Q9NVR5 1 +Abnormal circulating non proteinogenic amino acid concentration 0.7306549298000684 1.5625393532696463 0.1181609826256977 1.0 0.3326687174624453 7 P03886 1 +Abnormal esophagus physiology 0.305022151933298 1.5618815696654809 0.1183158910170329 1.0 0.3326687174624453 220 Q99720,Q96RR1,Q03164,P03886,Q8WWI5,P00846,Q8NC96,P48735,Q96RL7,P57678,Q86U42,Q05086,P51571,Q9BQP7,Q96F07,Q8N3U4,P83436,Q96PU5,Q14739,Q9UEY8,O75874,O43791,O43819,Q9NSE4 24 +Microcornea 0.4539551897485668 1.5616090067227208 0.1183801263906096 1.0 0.3326687174624453 29 Q71SY5,P52732,Q15555,Q9BZK7,Q9NWM8,Q96J42,O75845 7 +Postaxial polydactyly 0.5172026328693631 1.5604486235169592 0.1186539019998496 1.0 0.3329234847759204 17 Q14739,Q9UM00,Q10713,Q96J42,O75845 5 +Ophthalmoparesis 0.3694706795748015 1.559797504073683 0.1188077414900719 1.0 0.3329234847759204 70 Q9P2R7,Q96RR1,P03886,Q15555,Q13586,O43819,Q9BQP7,P00846,Q12824,Q9P0J0,Q86U42,Q96IX5 12 +Duplication involving bones of the feet 0.5627132424235729 1.5592639153359895 0.1189339286290653 1.0 0.3329234847759204 14 O75845,Q14739,Q96J42,Q10713 4 +Involuntary movements 0.2720793210312107 1.5585165748645446 0.1191108419939579 1.0 0.3329234847759204 321 Q9NPL8,Q99720,P13073,Q9NZ01,Q96RR1,Q03164,P03886,Q9Y619,Q8WWI5,Q10713,O60762,Q8IY17,P00846,Q8NC96,P41440,Q9NP72,Q6P4A7,P17480,Q9UBB6,P00374,O14653,Q96RL7,Q96AA3,O00400,Q96IX5,Q9H9B1,Q05086,Q9BRK0,O75845,Q9P2R7,Q68CP9,Q9NQT5,Q9NUQ7,Q9BQT8,Q96N67,P61457,O15160,O14802,Q96F07,Q9BUK6,O95831,Q9NQH7,Q86VD7,Q9Y5P4,Q8TD30,Q6DKK2,Q71SY5,Q9C0E8,P07196,O43791,O43819,Q96CU9,O95363,Q9H6K4,Q9BXJ9,O60313,Q9P0J0,Q12824,O96008 59 +Severe global developmental delay 0.3718268936856387 1.5583886674259857 0.1191411414035896 1.0 0.3329234847759204 67 O75381,Q9H7D7,O96011,Q71SY5,P03886,O75648,Q9BZK7,P57678,O60566,Q6P2C8,Q7LGA3,P51812,O60762,P00846,Q9BT22 15 +Abnormal glycosylation 0.4705265454029426 1.557842718195518 0.1192705367470667 1.0 0.3329234847759204 25 Q14746,P51571,Q9UP83,Q96AA3,P34949,Q9NP73,Q9Y487,O60762,Q9BT22 9 +Fair hair 0.7538168848215467 1.5578061454417276 0.1192792087839555 1.0 0.3329234847759204 4 Q05086 1 +Abnormality of the frontal hairline 0.3700557012453842 1.5567555808208424 0.1195285269615364 1.0 0.3331090613550665 77 Q68CP9,Q9UP83,O43791,Q9UM00,Q9BZK7,Q96N67,Q7LGA3,P46783,O15160,O96028,O95831,Q9NR45,Q9NP72,Q8N3U4,P83436,Q12824 16 +Abnormal pyramidal sign 0.3308432250702849 1.5564052342881007 0.1196117613121234 1.0 0.3331090613550665 123 Q99720,Q9Y619,Q9NP73,Q8WWI5,Q8IY17,P00846,P41440,Q9H9P8,P17480,P51812,O00400,Q9BRK0,Q9NZ08,Q13217,O14802,O95831,Q8TD30,Q6DKK2,Q9UEY8,P07196,O95363,Q9H6K4,Q99653,O60313,Q9P0J0 25 +Reticulated skin pigmentation 0.5890366526110864 1.5563909824490263 0.1196151481850926 1.0 0.3331090613550665 2 Q9NX24 1 +Mixed demyelinating and axonal polyneuropathy 0.7508544650658355 1.5562871198048815 0.1196398328531331 1.0 0.3331090613550665 5 P03886 1 +Abnormality of the metaphysis 0.3996026917910394 1.555013762828884 0.1199427915783446 1.0 0.3333768542308217 47 Q14739,Q13126,P48735,Q99575,Q96DX4,Q9H1A4,O75874,Q96HY6,Q9HC07,O95831,Q9NR45,Q9NSE4 12 +Chromosome breakage 0.6315994270057791 1.5513939792361933 0.120807297200093 1.0 0.3353290786252584 11 P13073,Q9BXW9,Q9NVI1,P38398,Q12824 5 +Retinal vascular tortuosity 0.5610102990518779 1.5493626666250098 0.121294563059247 1.0 0.3360183640922723 14 P03886 1 +Babinski sign 0.3660793608133548 1.5474437842870037 0.1217562701869621 1.0 0.3365197705594498 90 Q99720,Q9NP73,Q8WWI5,Q8IY17,P00846,P41440,P51812,O00400,Q9BRK0,Q13217,O14802,O95831,Q8TD30,Q6DKK2,P07196,O95363,Q9H6K4,Q99653,O60313 19 +Small basal ganglia 0.7063583094413306 1.5445655920166057 0.1224513742542441 1.0 0.3376169965743919 8 P00846,Q9NR45 2 +Flat occiput 0.5590548383848815 1.537989327524407 0.1240512242941591 1.0 0.3399588905339026 14 O75381,O96011,P52732,O60762,Q05086 5 +Antiphospholipid antibody positivity 0.5844956211482266 1.5329295947173458 0.1252932030693556 1.0 0.3404788301764733 2 P49327 1 +Abnormal myelination 0.3061168394426152 1.531204664229714 0.1257188184182034 1.0 0.3412260320158547 212 Q9NPL8,Q99720,P49419,P03886,Q5BJH7,Q13614,P00846,Q8NC96,P41440,O43676,Q9H9P8,Q9UBB6,P00374,Q96RL7,Q13868,P57678,Q05086,Q6P2C8,Q96F07,O95831,P83436,Q8TD30,P07196,Q9UP83,O43819,Q96CU9,O96000,Q9P0J0 28 +Postaxial hand polydactyly 0.6764083177604446 1.528470572393222 0.1263957445141339 1.0 0.3421747277652885 9 Q14739,Q96J42,O75845,Q9UM00 4 +Single transverse palmar crease 0.4056578352917896 1.528267944914964 0.1264460252271728 1.0 0.3421747277652885 44 O75381,O96011,Q71SY5,Q96J02,Q6DKJ4,P51812,O96028,Q8IY17,Q9H9B1,Q15907 10 +Segmental peripheral demyelination remyelination 0.7437988507866896 1.5271643619463304 0.126720145730258 1.0 0.3427117971092948 5 P00846,P03886 2 +Rheumatoid factor positive 0.582549464807001 1.5228666951139185 0.1277920596543813 1.0 0.3447873914439234 2 P49327 1 +Status epilepticus 0.4097516242110521 1.5145621486559382 0.1298833238990639 1.0 0.3494114759285959 42 Q15392,P49419,Q96RR1,Q96F07,Q8NC96 5 +Platyspondyly 0.4357743990439335 1.5110065604045404 0.1307867794158963 1.0 0.3511939008618912 33 Q14739,Q96AY3,P48735,Q96DX4,Q9NUQ7,Q6NUQ1,O75874,Q32P28,Q96HY6,O95831,Q9NR45 11 +Annular pancreas 0.6599610642439948 1.5087876126922712 0.1313530673480678 1.0 0.3513230282440378 3 Q9BXW9,Q9Y4R8 2 +Visual loss 0.3949690427768307 1.5083481474602387 0.1314654465337126 1.0 0.3513230282440378 47 P52732,P03886,Q8IY17,P00846,P53701,O60313,Q12824 7 +Keratitis 0.6713574593717435 1.5047584590326253 0.1323861873582412 1.0 0.3529778862465173 9 Q14739,P06132,Q9NSE4 3 +Sloping forehead 0.4196345356251228 1.5023089365674902 0.1330173417715472 1.0 0.3541947789507028 37 Q9BXW9,Q16625,Q15021,Q9NVI1,P52732,P38398,O60566,P26640,P98175,Q08J23,Q8N3U4,Q96J42,O75845 13 +Atrophy degeneration involving the caudate nucleus 0.7377124641803924 1.5020137448196316 0.1330935591456352 1.0 0.3541947789507028 5 P00846 1 +Postural tremor 0.4891744632382865 1.5014719643064078 0.1332335327443703 1.0 0.3541947789507028 20 P00846,P03886 2 +Aplasia hypoplasia involving the vertebral column 0.5761770509056683 1.500984735732871 0.1333595096678832 1.0 0.3543217470941414 13 Q6NUQ1,Q14739,Q96HY6,O95831 4 +Deep plantar creases 0.7340194760065601 1.4980764276978509 0.1341133946889661 1.0 0.3555051424331684 6 Q9Y487,Q9BZK7 2 +Tube feeding 0.3640961108856915 1.4950315052299976 0.1349062200381021 1.0 0.3565491113025687 70 Q8TD30,Q99720,Q9NZ01,Q9NUQ7,Q9UBB6,Q71SY5,Q9H1A4,O43791,Q13724,O75648,Q9UP83,Q96J02,O60762,Q8N3U4 14 +Abnormality of hand joint mobility 0.6561246793141013 1.4912316636485916 0.1359006832226219 1.0 0.3581326905168571 3 P51812 1 +Hyperextensibility of the finger joints 0.6561246793141013 1.4912316636485916 0.1359006832226219 1.0 0.3581326905168571 3 P51812 1 +Progressive external ophthalmoplegia 0.5961943775069367 1.4850318827928684 0.1375353785630135 1.0 0.3609706053826486 12 Q96RR1,P03886,Q9BQP7,P26640,O60313 5 +Anophthalmia 0.6928621927679668 1.4838748601894185 0.137842122424423 1.0 0.3613569528834701 8 P53701,Q96J42,Q96N67 3 +Albinism 0.574764839442095 1.4825708146196437 0.1381884760968723 1.0 0.3614378514043649 2 O00203 1 +Distal joint laxity 0.6537962362102518 1.4805704508779431 0.1387210743484384 1.0 0.3623966890339201 3 Q02809,Q9H553 2 +Abnormality of the brainstem white matter 0.6531951572911554 1.477817611316165 0.1394566031934512 1.0 0.3634858529725742 3 Q10713 1 +Gastrostomy tube feeding in infancy 0.4273263704799265 1.4685046616383428 0.1419671909188449 1.0 0.3691798937212213 34 Q99720,P17480,Q9H7D7,Q05639,Q9UP83,O43791,Q96J02,O60762,Q8N3U4 9 +Basal ganglia calcification 0.7261339862847385 1.4651324975166005 0.1428847718736396 1.0 0.3709920133956618 6 P03886 1 +Hypoketotic hypoglycemia 0.6625292101855694 1.4632732746900037 0.1433926175478497 1.0 0.3718194376026097 9 O43772 1 +Glomerular deposits 0.5708725267596426 1.4623986280494206 0.1436320051821331 1.0 0.3720142844340007 2 P52565 1 +Hypoplasia of the ear cartilage 0.570872526759642 1.4623986280494174 0.143632005182134 1.0 0.3720142844340007 2 Q8WUM0 1 +Abnormal iris pigmentation 0.5015414181612299 1.4592791839890944 0.1444882822760664 1.0 0.3740182392631892 17 O75381,Q05086,Q8IY17 3 +Cns hypomyelination 0.4086008217618218 1.4582916495032736 0.1447601709418833 1.0 0.3745080379021881 40 Q99720 1 +2 3 toe cutaneous syndactyly 0.6481133408271832 1.4545331224634015 0.1457985572944957 1.0 0.376252603691811 3 Q6W2J9 1 +Cystic renal dysplasia 0.5692507298086219 1.4539892472619995 0.1459492873726831 1.0 0.376252603691811 2 Q8TD19 1 +Agyria 0.6475672693068759 1.452029987943594 0.1464932671829568 1.0 0.3768395799766011 3 Q00535 1 +Rhabdomyolysis 0.5301673912090001 1.4517128096261769 0.1465814760511117 1.0 0.3768524895071146 15 O43772 1 +Hemiplegia hemiparesis 0.4278847050665025 1.4444264428386118 0.1486190569928931 1.0 0.3795363951743336 33 Q9NZ08,O43791,P03886,P50416,Q8IY17,Q12824 6 +Abnormal circulating copper concentration 0.7033535985628345 1.4443846395865154 0.148630809059441 1.0 0.3795363951743336 7 O43819,Q9Y487 2 +Thoracic kyphosis 0.542226886356629 1.439977783573921 0.149873684638917 1.0 0.3824945303742502 14 Q99575 1 +Mitochondrial myopathy 0.4295090051069232 1.431586959657749 0.1522620638218543 1.0 0.3861966120453529 32 O43676,Q96RR1,P03886,Q96CU9,O96000,Q9BUK6,P00846 7 +Type i diabetes mellitus 0.6074053180218159 1.427689504040082 0.1533812485574024 1.0 0.3879492216443512 11 P03886,Q5JRA6,Q96J02 3 +Abnormal protein glycosylation 0.4728149271632929 1.4228398127687087 0.1547825971205445 1.0 0.3904037666793244 21 P51571,Q9UP83,Q96AA3,P34949,Q9NP73,Q9Y487,O60762,Q9BT22 8 +Eeg with focal epileptiform discharges 0.4143900268362475 1.4200525902919896 0.155592371104563 1.0 0.3913435058768064 36 Q9NUQ7,P49419,Q9UBB6,Q71SY5,Q96N67,Q05086 6 +Hyperammonemia 0.4180393412818092 1.4192800333206803 0.1558173908620694 1.0 0.3914879537466304 35 P11310,Q86VD7,O43772 3 +Brisk reflexes 0.452067101052867 1.4188911289420338 0.1559307589806624 1.0 0.3915556198350337 25 Q99720 1 +Abnormal gastrointestinal motility 0.4516120126441717 1.4154654809576133 0.1569320624421921 1.0 0.3925467934086861 25 P03886,Q9NSE4,Q96RR1 3 +Abnormal shape of the occiput 0.4439229267313838 1.413413111688016 0.1575342926080383 1.0 0.3934015135140096 27 O75381,O96011,P52732,Q13724,Q96J02,O60762,Q05086 7 +Focal t2 hyperintense basal ganglia lesion 0.4604658962989574 1.4124578686353535 0.1578151876684423 1.0 0.3937194588850127 23 P00846,P03886,Q9P0J0 3 +Aplasia hypoplasia of toe 0.4135200521384485 1.4123890504959713 0.1578354387053384 1.0 0.3937194588850127 36 P13073,Q03164,O75648,Q9BZK7,Q6P2C8,Q15427,Q7LGA3 7 +Short palpebral fissure 0.4386571868908362 1.4042701038556835 0.1602384332125861 1.0 0.3981788823110341 28 Q9BXW9,Q03164,Q15555,Q13724,Q13868,P83436 6 +Lumbar scoliosis 0.6365996106424403 1.4017173365333702 0.1609996715472657 1.0 0.3983841445862364 3 P27635,P21281 2 +Metamorphopsia 0.5588712293220806 1.4001176415415502 0.1614780930287458 1.0 0.3983841445862364 2 Q99496 1 +Inferior lens subluxation 0.5588712293220806 1.4001176415415502 0.1614780930287458 1.0 0.3983841445862364 2 Q99496 1 +Abnormal ciliary body morphology 0.5588712293220806 1.4001176415415502 0.1614780930287458 1.0 0.3983841445862364 2 Q99496 1 +Uveal melanoma 0.5588712293220806 1.4001176415415502 0.1614780930287458 1.0 0.3983841445862364 2 Q99496 1 +Lens subluxation 0.5588712293220806 1.4001176415415502 0.1614780930287458 1.0 0.3983841445862364 2 Q99496 1 +Photopsia 0.5588712293220806 1.4001176415415502 0.1614780930287458 1.0 0.3983841445862364 2 Q99496 1 +Choroidal melanoma 0.5588712293220806 1.4001176415415502 0.1614780930287458 1.0 0.3983841445862364 2 Q99496 1 +Mydriasis 0.5588712293220806 1.4001176415415502 0.1614780930287458 1.0 0.3983841445862364 2 Q99496 1 +Ocular pain 0.5588712293220806 1.4001176415415502 0.1614780930287458 1.0 0.3983841445862364 2 Q99496 1 +Abnormality of the palpebral fissures 0.2996742861745818 1.40009336041169 0.1614853630589063 1.0 0.3983841445862364 212 Q15392,Q03164,Q15555,Q9Y619,Q9NP73,Q9Y487,O60762,Q8NC96,Q9NP72,O75381,Q9BXW9,P78318,P63000,O96011,Q9UM00,P38398,Q9BZK7,Q5KU26,Q6W2J9,Q13868,Q6DKJ4,P51812,Q9H553,Q9HCK8,Q9H9B1,P38159,P61586,Q15907,Q05086,O75845,Q6PGP7,P26196,Q68CP9,Q05639,P80404,Q12797,Q9NVI7,Q6P2C8,O75648,O60566,Q13724,O15160,O14802,Q96F07,P98175,Q08J23,Q8N3U4,P83436,P61981,Q71SY5,Q9NVI1,P42345,O43791,P52732,Q15427,Q7LGA3,Q13555,Q9Y5P4,O96028 59 +Elevated urinary monocarboxylic acid level 0.7149413196403649 1.3984867644408088 0.161966944485336 1.0 0.3991894768871448 4 P11310 1 +Mental deterioration 0.3540734307738629 1.398120458903591 0.1620768971491024 1.0 0.3992432539888168 91 Q96RR1,Q03164,P03886,O43819,Q8WWI5,Q9Y487,Q96F07,Q8IY17,P00846,Q8NC96 10 +Optic disc pallor 0.3725761189161471 1.392490601904919 0.1637738855958663 1.0 0.4029851720528379 51 O43676,Q9H6K4,P03886,Q96CU9,O96000,Q9BUK6,P00846,O95831 8 +Intestinal pseudo obstruction 0.6206044499400359 1.3868027146212798 0.1655019291255879 1.0 0.4059143145310846 10 P03886 1 +Redundant neck skin 0.7073024163380064 1.3863415315015852 0.1656426407692866 1.0 0.4059246910525046 6 Q9Y487 1 +Abnormal hypothalamus physiology 0.7069814258960059 1.3849974805421463 0.166053237754951 1.0 0.4063863679254069 6 Q12824 1 +Extra axial cerebrospinal fluid accumulation 0.5556276354200411 1.383267489913821 0.1665828624660972 1.0 0.4068034323296208 2 Q03252 1 +Alternating esotropia 0.5556276354200376 1.3832674899138022 0.166582862466103 1.0 0.4068034323296208 2 Q14738 1 +Supernumerary spleens 0.6193418087734504 1.380583194645124 0.1674071534450676 1.0 0.4083760932181778 10 Q9NVR5,Q96J42 2 +Slender long bone 0.5182592663516813 1.3799591468477843 0.1675992237301891 1.0 0.4086245874584265 15 Q32P28,Q9Y487,Q96DX4,Q96J02 4 +Abnormal head movements 0.5976168584711842 1.377562005056182 0.1683385585476582 1.0 0.4096647892859848 11 Q99720 1 +Congenital hepatic fibrosis 0.7074889858886133 1.3768269950832466 0.1685657425767233 1.0 0.4096647892859848 5 Q96J42,Q8IY17 2 +Aplasia hypoplasia of the femur 0.5035131102197357 1.376672163390767 0.1686136287889614 1.0 0.4096647892859848 16 O95831,Q9NR45,Q96HY6,Q99575 4 +Localized osteoporosis 0.5543301978592201 1.376525806473596 0.1686589033153116 1.0 0.4096647892859848 2 P57740 1 +Sudden episodic apnea 0.7072756626915004 1.375942183351995 0.1688395339204782 1.0 0.4098837559805822 5 O43772 1 +Fluctuations in consciousness 0.7046221556668961 1.375118027787109 0.1690948561624474 1.0 0.4102837163448779 6 P03886 1 +Sensory neuropathy 0.4087941336214929 1.3707869928885723 0.1704413668375493 1.0 0.4117431140524201 36 Q96RR1,P03886,P00846,O95831,Q9NSE4 5 +Abnormality of the parathyroid gland 0.4764851105282725 1.3702615871203716 0.1706052593987621 1.0 0.4117431140524201 19 P03886,P48735 2 +Abnormality of earlobe 0.441729955778775 1.3673505492817897 0.1715154544074331 1.0 0.4130595472970079 26 Q15392,Q9BZK7,Q96N67,Q7LGA3,P53701,Q9H9B1 6 +Protruding tongue 0.5518709471006915 1.3656222608680442 0.1720575557968053 1.0 0.4139249749121234 13 Q96RL7,Q10713,P83436,Q05086 4 +Aplasia hypoplasia of the uvula 0.7022099839816424 1.3650158996238182 0.172248052804385 1.0 0.4141633116793334 6 Q9BXW9,Q9NVI1,Q6DKJ4 3 +Abnormal lactate dehydrogenase level 0.5156558289435494 1.3642700232669345 0.1724825968284746 1.0 0.4142874674618187 15 P11310,P41440 2 +Facial hypertrichosis 0.3640435720583169 1.3599876778867668 0.1738338232544092 1.0 0.417090688211056 57 Q03164,Q9UM00,O43791,O75648,Q6P2C8,Q96N67,P06132,Q9Y5P4,Q9NR45,Q9H9B1 10 +Myoclonus 0.3516726091220584 1.3562101110165228 0.1750323258770292 1.0 0.4190784546632887 89 Q9NPL8,P13073,Q96RR1,P00374,P03886,O14653,Q96CU9,Q96AA3,Q96N67,O95363,Q96F07,P00846,Q8NC96,Q12824,Q05086 15 +Epispadias 0.703992210321327 1.3534920139595752 0.175898499612578 1.0 0.4206245658117284 4 P53701,Q9Y619,P48651 3 +Anteverted ears 0.6252433484750147 1.3495641154506524 0.177155841244482 1.0 0.4217298963367933 3 P27635,Q6W2J9 2 +Vertebral compression fracture 0.5131344239966464 1.3490764228743803 0.1773124203426319 1.0 0.4217298963367933 15 Q96HY6,Q32P28 2 +Retinal dysplasia 0.6979955013939063 1.347363622261586 0.1778631506492918 1.0 0.4227282646596495 6 P53701,P52732 2 +Abnormal diaphysis morphology 0.3568908138574908 1.3439938873062018 0.1789503635703242 1.0 0.4246494194185403 64 Q14739,Q13126,Q96AY3,Q96DX4,Q9NUQ7,Q9H1A4,Q9UP83,Q9Y619,Q32P28,Q7LGA3,Q96HY6,Q9Y487,Q9HC07,P51812,Q96J42,Q9NSE4 16 +Tremor by anatomical site 0.4267694974931688 1.3439866548559738 0.1789527023554069 1.0 0.4246494194185403 29 Q99720,Q96RL7,Q05086 3 +Irregular vertebral endplates 0.6993920982076633 1.3432371508818417 0.1791951955904709 1.0 0.4248559103966575 5 Q9NR45,O15228 2 +Aplasia hypoplasia involving the femoral head and neck 0.6117403516173109 1.3431379948651367 0.1792272946507753 1.0 0.4248559103966575 10 O95831,Q9NR45,Q96HY6,Q99575 4 +Bilateral single transverse palmar creases 0.5120192747559017 1.342357290242876 0.1794801758792235 1.0 0.4250863270941445 15 O75381,Q8IY17 2 +Abnormal lower limb bone morphology 0.3115574294223957 1.3413665548087117 0.179801470813824 1.0 0.4255489356251948 162 P13073,Q15392,Q5JRA6,Q03164,Q6NUQ1,Q9Y619,Q96HY6,Q9Y487,Q9NR45,Q96J42,Q9BXW9,Q96AY3,Q99575,Q9H1A4,Q9BZK7,Q32P28,O75845,Q96DX4,Q9NUQ7,O75648,Q6P2C8,O95831,Q14739,Q71SY5,Q15427,Q7LGA3,Q13555,Q9Y5P4 28 +Respiratory insufficiency 0.3054203912725671 1.3380317839388165 0.1808860760202695 1.0 0.4272231096829097 177 Q9NPL8,P49419,Q92804,O43772,Q96RR1,P03886,Q70HW3,O43676,O75381,Q96AY3,O96011,Q96AA3,Q8NFF5,Q9P2R7,Q9NQT5,Q8WXH0,O75648,Q13586,Q9BQP7,Q9NVR5,O95831,P83436,Q14739,Q96B26,O43791,O43819,Q96CU9,Q15427,O96000 29 +Aplasia hypoplasia involving bones of the lower limbs 0.3505871919120505 1.3335680702921835 0.1823454530484736 1.0 0.4303988808491004 87 P13073,Q96AY3,Q99575,Q96DX4,Q5JRA6,Q03164,Q9H1A4,O75648,Q9BZK7,Q6P2C8,Q15427,Q7LGA3,Q96HY6,Q13555,Q9Y5P4,O95831,Q9NR45 17 +Barrel shaped chest 0.6986758007634409 1.3316360893756278 0.1829797998139333 1.0 0.4314932291291608 4 Q32P28 1 +Abnormal brainstem mri signal intensity 0.4490062432486225 1.3291002119689173 0.1838149103700863 1.0 0.4326547432710424 23 O43676,P03886,Q96CU9,O96000,O95831 5 +Fatigable weakness of skeletal muscles 0.6584977744505468 1.3289805444349332 0.1838543886968557 1.0 0.4326547432710424 8 P11310 1 +Abnormal pharynx morphology 0.4036648200652341 1.3257026834326604 0.1849381982348106 1.0 0.4343027672388242 36 Q9NVR5,Q13432,Q12824,Q03518 4 +Aplasia hypoplasia of the sternum 0.6950594133117133 1.3252598149046877 0.1850849923946098 1.0 0.4344222878484884 5 Q9Y619,P98175,O60566 3 +Cerebellar atrophy 0.3129851742145779 1.3227649502271022 0.1859135565068013 1.0 0.4359153265920341 138 P13073,Q9UHD1,Q96RR1,Q5BJH7,P26640,Q8WWI5,Q10713,O60762,Q8IY17,P41440,Q9H9P8,P17480,P18887,Q13868,O00400,O75845,Q9NQT5,O75648,Q13217,Q6P2C8,Q9BQP7,O15160,O14802,Q96F07,P83436,Q6DKK2,Q9C0E8,Q9UP83,Q96CU9,P49959,O95363,Q96D71,Q9H6K4,Q99653,O60313 35 +Facial diplegia 0.6074863597519966 1.3221842274698894 0.1861068119009137 1.0 0.4361427097315774 10 Q9P2R7,O43819 2 +Abnormality of the curvature of the vertebral column 0.2601171235866176 1.3205059251901872 0.186666159075024 1.0 0.4366115468576731 308 Q99720,Q5BJH7,Q96HY6,Q9Y487,Q13614,Q9BXW9,Q96AY3,P48735,Q99575,Q9UM00,O14653,Q9BZK7,Q32P28,Q9NWM8,Q9HC07,Q8NFF5,Q05086,Q96DX4,Q9NUQ7,Q9BQT8,P51571,Q8WXH0,Q13724,O75648,Q6P2C8,Q9BQP7,Q9BUK6,O95831,Q8N3U4,O15228,Q96PU5,Q14739,P07196,O75874,Q96CU9,Q15427,O95363,Q12824,Q9NSE4 39 +Multiple enchondromatosis 0.6938491362377945 1.3202379408752634 0.1867555881704303 1.0 0.4366115468576731 5 O75874,P48735 2 +Synostosis involving digits 0.6952625595488714 1.3176027994734083 0.1876366479804168 1.0 0.4383672075045323 4 Q9H1A4 1 +Abnormal ilium morphology 0.4674897243545763 1.30965754612867 0.1903117115042691 1.0 0.4427899605107033 19 O95831,Q9NR45,P51812,Q99575 4 +Abnormal sacrum morphology 0.4086961721580747 1.3093359821899386 0.1904205662257718 1.0 0.4428068905155224 34 Q14739,Q03164,Q9UM00,O43791,Q6DKJ4,P53701,O96028 7 +Skin appendage neoplasm 0.6918775444472425 1.3036852975567574 0.1923409043438573 1.0 0.44590803310014 4 Q14145 1 +Femoral bowing 0.6279812155979396 1.3006858503651268 0.1933660075288996 1.0 0.4473687508201815 9 Q32P28 1 +Abnormal 3rd finger morphology 0.6141468392405911 1.2985759444232348 0.1940894978648386 1.0 0.4485844006774077 3 Q71SY5 1 +Abnormality of metacarpal epiphyses 0.6882801974205957 1.2971308104616532 0.1945861820170611 1.0 0.4490821995129627 5 P51812 1 +Holoprosencephaly 0.6272158317895781 1.2970839989062426 0.1946022864556171 1.0 0.4490821995129627 9 Q96J42,Q8N3U4,O60566 3 +Impaired vibration sensation in the lower limbs 0.504122312980111 1.2947932639787527 0.1953915563247155 1.0 0.4506652411083036 15 P00846,Q9BRK0 2 +Muscle fiber inclusion bodies 0.6265545434550386 1.293972163006061 0.195675036289912 1.0 0.4508687255306721 9 O43676,Q13586,Q9H553,P07196 4 +Gait ataxia 0.3493493867519662 1.2934381391712506 0.1958595663945286 1.0 0.4509496993544923 67 P03886,Q8IY17,P00846,P41440,Q05086 5 +Panniculitis 0.6847655370237452 1.291945947808694 0.1963758640142372 1.0 0.4513666845717931 6 P28070 1 +Dyskinesia 0.3480334003561732 1.2916905686761049 0.1964643249170654 1.0 0.4513666845717931 68 Q9UBB6,P03886,O43819,Q5BJH7,Q96F07,P00846,Q8NC96,Q9P0J0 8 +Short attention span 0.3106504056873327 1.29108401421068 0.196674546602015 1.0 0.4513666845717931 125 Q9NZ01,Q03164,P03886,Q9NP73,Q8NC96,Q9BXW9,Q9UBB6,Q9H1A4,Q9UM00,Q96RL7,P51812,Q05086,Q9NUQ7,O75648,Q6P2C8,Q96F07,Q8N3U4,Q71SY5,P52732,Q7LGA3,Q9BXJ9 21 +Abnormal visual electrophysiology 0.3811433101073586 1.291044452154767 0.1966882638730065 1.0 0.4513666845717931 44 Q9P2R7,Q15555,Q13724,Q8IY17,P00846,O60313 6 +Abnormality of circulating adrenocorticotropin level 0.6495254963167536 1.2885234729086783 0.1975638032986038 1.0 0.4516706221275127 8 Q13423 1 +Retinopathy 0.4198101955237895 1.2884405218217605 0.1975926607095528 1.0 0.4516706221275127 29 Q9NZ08,Q5JRA6,P52732,Q15555,O43819,P00846,P11802 7 +Ventriculomegaly 0.3026328849927535 1.2873397795111785 0.1979758841519219 1.0 0.4518039069058973 177 Q9NPL8,Q16625,Q15392,P49419,O94979,Q9Y487,Q10713,O60762,P00846,Q9NR45,Q9NP72,Q96J42,Q9BXW9,P17480,Q9UM00,Q96RL7,Q9BZK7,P51812,Q9H9B1,Q68CP9,Q9P2R7,O60566,Q9NVR5,O14802,Q96F07,Q71SY5,P42345,Q9UP83,O43819,Q96CU9,O95363,P49959,O96028,Q12824 34 +Myoclonic spasms 0.6831068508227796 1.2849990154943454 0.1987926280628116 1.0 0.4532111752010753 6 P00846,Q12824 2 +Abnormal circulating nitrogen compound concentration 0.3620315163719994 1.2817733411502097 0.1999221685639702 1.0 0.4550992078365755 51 P50416,P11310,Q86VD7,O43772 4 +Functional motor deficit 0.3104791402113452 1.2812546435657652 0.2001042384536613 1.0 0.455215304219598 148 Q8TD30,Q99720,Q96DX4,Q96RR1,P03886,O14653,O43819,Q96RL7,Q13586,Q9NWM8,Q9BQP7,Q96F07,Q9BUK6,P00846,Q8NC96,Q12824,Q05086 17 +Abnormality of the extrinsic pathway 0.683877753480157 1.2788657508541723 0.2009443351349045 1.0 0.4563540110747906 5 P38435,P34949 2 +Impaired vibratory sensation 0.4111035999499353 1.2787909155357031 0.2009706938151072 1.0 0.4563540110747906 32 Q96RR1,P07196,Q96RL7,O43819,Q9Y619,O00400,P00846,Q9BRK0 8 +Thoracolumbar scoliosis 0.6468055503897947 1.2762630059628337 0.2018625627897123 1.0 0.4578822138534079 8 Q99575 1 +Progressive 0.339284420298525 1.2760525925535957 0.2019369283916339 1.0 0.4578822138534079 100 Q8TD30,Q99720,Q13126,P61619,Q96RR1,P18887,O14653,Q96RL7,Q13586,Q9BQP7,Q96D71,O60762,O00400,Q8IY17,O95831,O60313,Q86U42 17 +Absent forearm bone 0.6850377072025885 1.2755652744888166 0.2021092360269216 1.0 0.4578822138534079 4 Q15427 1 +Abnormal left ventricular outflow tract morphology 0.608697984750897 1.2735382174505347 0.2028271200031619 1.0 0.4589444823248369 3 O60566 1 +Subvalvular aortic stenosis 0.608697984750897 1.2735382174505347 0.2028271200031619 1.0 0.4589444823248369 3 O60566 1 +Muscle fiber atrophy 0.4560184028591812 1.2730784536388908 0.2029902038552982 1.0 0.4590841854540693 20 Q99720,Q96RL7,Q13586 3 +Abnormal femoral neck head morphology 0.3765541459606112 1.2724218025018688 0.2032232916299383 1.0 0.4593819915586929 45 Q14739,Q96AY3,Q99575,Q96DX4,Q9NUQ7,Q6NUQ1,Q9Y619,Q7LGA3,Q96HY6,Q9Y487,O95831,Q9NR45 12 +Visual impairment 0.2676970777003281 1.271499161134124 0.2035511256828006 1.0 0.459848535966336 265 Q9NPL8,Q9NZ01,Q96RR1,P03886,Q13432,Q15555,Q5BJH7,P06132,Q10713,O60762,Q8IY17,P00846,O43676,O75381,Q6P4A7,Q9BXW9,O96011,Q9UBB6,Q96AA3,P61586,Q9P2R7,Q9NZ08,Q9NUQ7,O75648,Q6P2C8,Q96N67,O95831,P53701,Q8N3U4,Q9Y5P4,Q96B26,Q71SY5,Q9UP83,P52732,O43819,Q96CU9,Q7LGA3,O96000,O95363,Q9H6K4,Q99653,O60313,Q12824 43 +Limb muscle weakness 0.3468247461994097 1.2712697302049594 0.2036327070967925 1.0 0.459848535966336 79 Q99720,Q14739,Q13126,Q96RR1,P07196,Q9BQT8,O43819,Q96RL7,Q8IY17,P00846,Q86U42,Q12824,O15269 13 +Hyperactivity 0.3099835751834172 1.270876205418392 0.2037726926831131 1.0 0.459935375114351 145 Q9NZ01,Q03164,Q9NP73,Q10713,Q8NC96,Q9BXW9,P17480,Q9UBB6,Q9H1A4,Q9UM00,Q96RL7,Q12955,P51812,Q05086,Q9NUQ7,O75648,Q6P2C8,Q96F07,Q8N3U4,Q71SY5,Q9C0E8,P52732,Q7LGA3,Q9BXJ9,Q12824 25 +Abnormality of vitamin b12 metabolism 0.576327941048772 1.268556070987028 0.2045994404546358 1.0 0.4603774737123532 11 P41440 1 +Clitoral hypoplasia 0.6813834630089642 1.268518758589907 0.204612756113421 1.0 0.4603774737123532 5 Q9NP72,Q9Y619 2 +Hypoplastic labia minora 0.6813834630089642 1.268518758589907 0.204612756113421 1.0 0.4603774737123532 5 Q9NP72,Q9Y619 2 +Excessive wrinkled skin 0.6450454192153163 1.2683304623486014 0.2046799629264193 1.0 0.4603774737123532 8 Q9BZK7 1 +Myositis 0.6448072280914972 1.2672570816273927 0.2050633812613687 1.0 0.4608284375124982 8 P28070 1 +Hypertrichosis 0.3353179960290233 1.2665759549104485 0.2053069546506751 1.0 0.4611008946790077 104 Q68CP9,Q03164,O43791,P03886,O43819,Q96CU9,Q6P2C8,Q96N67,Q9UM00,O75648,P06132,Q9Y5P4,Q9NR45,Q9NP72,Q9H9B1,Q9P0J0,P83436,Q12824 18 +Sclerosis of skull base 0.606298557458971 1.262514147871454 0.2067638386730688 1.0 0.4634538293859483 3 Q14739 1 +Photophobia 0.4030089228593116 1.260945565540468 0.2073284598985281 1.0 0.4640305945357373 34 Q13432,Q8IY17 2 +Muscle abnormality related to mitochondrial dysfunction 0.3848326247930618 1.2584457281252115 0.2082306030515255 1.0 0.4654931820333294 41 Q9NPL8,O43676,Q96RR1,P03886,O75648,Q96CU9,O96000,O95363,Q9BUK6,P00846 10 +Cerebral cortical atrophy 0.3400174091977734 1.2582808166556585 0.2082902163314699 1.0 0.4654931820333294 97 Q16625,Q96RR1,P03886,Q9Y619,P00846,Q9NP72,P17480,Q9UM00,Q96RL7,Q96AA3,P51812,Q9H9B1,Q05086,O75648,Q6P2C8,Q96N67,Q96B26,Q7LGA3,Q9NSE4,O96008 20 +Congenital diaphragmatic hernia 0.4486548221822324 1.2535910863877304 0.2099906727354055 1.0 0.4681386552615093 21 P53701,Q8N3U4,P24468,O96028 4 +Axonal regeneration 0.6782130920548768 1.2475153559869805 0.2122085932410482 1.0 0.4718672101864526 4 P07196 1 +Central scotoma 0.5918116273144111 1.245028904255415 0.2131211256892222 1.0 0.4732542643981258 10 P00846,P03886,Q9H6K4 3 +Hypotelorism 0.406489408547401 1.2406504376882694 0.2147349108042084 1.0 0.4756719540063885 32 Q8TD30,Q8N3U4,Q13586,Q9BUK6 4 +Type ii lissencephaly 0.528057087252666 1.2399260842287112 0.2150027349656236 1.0 0.4760324483842986 2 P07942 1 +Proportionate short stature 0.4034218420825665 1.2387154636310054 0.2154508899355023 1.0 0.4763209529335798 33 Q14739,Q15392,Q5JRA6,P52732,Q96HY6,Q13555,Q8IY17,P53701 8 +Abnormality of the supraorbital ridges 0.4416640772931059 1.2384381773632138 0.2155536321222602 1.0 0.4763209529335798 22 O75381,O96011,O43791,P52732,P51812,Q9HCK8,P98175,Q08J23,Q6PGP7 9 +Epiphyseal stippling 0.5699777406029566 1.2360822461432497 0.2164279934468649 1.0 0.4780198977641628 11 Q14739,O75381,P38435 3 +Prenatal movement abnormality 0.352913852725137 1.2322740697539734 0.2178467226411107 1.0 0.4799393002033833 56 Q8NC96,Q70HW3,P49419 3 +Infection related seizure 0.4451668999382757 1.2292300844254842 0.2189855523097552 1.0 0.4813219563140181 21 Q8TD30,P11310 2 +Decreased number of large peripheral myelinated nerve fibers 0.671239954107008 1.2264586016489414 0.2200261449734908 1.0 0.4831402989480918 5 Q8TB36,O15269,P07196 3 +Hirsutism 0.3532259939589625 1.2258019504630564 0.2202732130439244 1.0 0.4834484763027993 54 Q68CP9,Q9P2R7,Q03164,Q15555,Q13724,Q9NR45,Q9NP72,Q12824 8 +Vertebral hypoplasia 0.5878397697062163 1.225501790642764 0.220386215828702 1.0 0.4834622555467409 10 Q6NUQ1,Q14739,Q96HY6 3 +Nemaline bodies 0.6725093329891095 1.2240825008177736 0.220921106670179 1.0 0.4841667214397248 4 O43676 1 +Preaxial hand polydactyly 0.6115246965923908 1.2233016020380756 0.2212158023056651 1.0 0.4844455533599636 9 Q9BXW9,Q96J42 2 +Long clavicles 0.5975916003310369 1.22252474748153 0.2215092511973782 1.0 0.4847521294319435 3 Q14739 1 +Peripheral axonal neuropathy 0.3530389099312708 1.220012182361094 0.2224602567635982 1.0 0.4863633991984074 53 Q96RR1,Q96RL7,P03886,Q8IY17,P00846,O95831 6 +Renal agenesis 0.3656388074684367 1.2145550711892177 0.2245358335647123 1.0 0.4892412571665793 47 Q9BXW9,Q15392,O43819,Q15427,P46783 5 +Abnormal proximal phalanx morphology of the hand 0.6701210321425141 1.2142743402066256 0.2246429808047501 1.0 0.4892412571665793 4 Q9BXW9 1 +Hammertoe 0.4532597416468938 1.2139977652736615 0.2247485775195699 1.0 0.4892412571665793 19 Q99720,Q9UHD1,P07196,Q8TB36,Q6W2J9,Q99653 6 +Abnormal bronchus morphology 0.4246718953045712 1.2132212162791136 0.2250452546363182 1.0 0.4896517788196549 25 Q9NVR5,Q13432,Q03518 3 +Abnormal macroscopic urine appearance 0.4630902722974161 1.2108373205786076 0.2259577587212549 1.0 0.4909298067181221 17 Q8NFH4,P52565,Q9Y5K6,Q8N1F7,Q9P2R3,P57740,Q8WUM0,P06132,Q14C86,P36551,Q12769 11 +Abnormality of chromosome stability 0.4900865117158983 1.2104006249164645 0.2261252022294118 1.0 0.4910580853783487 15 P13073,Q9BXW9,Q9NVI1,P38398,Q12824 5 +Dermal atrophy 0.4323785796880932 1.2085293092629903 0.226843729013098 1.0 0.4923189919794659 23 Q15392,Q9NWM8 2 +Abnormality of the hypothenar eminence 0.594497639231633 1.2083226199366053 0.2269231910051048 1.0 0.4923189919794659 3 Q7Z392 1 +Downslanted palpebral fissures 0.3054932334963874 1.2076204449077332 0.22719329140654 1.0 0.4926690330644452 135 Q15392,Q03164,Q15555,Q9NP73,Q9Y487,O60762,Q8NC96,P78318,Q9UM00,Q6DKJ4,P51812,Q9H553,O75845,Q05086,Q6PGP7,Q68CP9,Q05639,O75648,O60566,Q6P2C8,O15160,O14802,Q96F07,Q71SY5,P42345,O43791,P52732,Q15427,Q7LGA3,O96028 30 +Abnormal sternal ossification 0.6664944973640369 1.206795605083748 0.227510869028559 1.0 0.4931216443537666 5 O96028,Q9Y619 2 +Inability to walk 0.340840765575391 1.2050792444597886 0.2281727115063558 1.0 0.4933745667215971 85 Q99720,Q9P2R7,Q71SY5,Q96RR1,Q9C0E8,P07196,Q96RL7,Q96CU9,Q96N67,Q8N3U4,O95363,Q9BUK6,P00846,P57678,O15269 15 +Aplasia hypoplasia involving the carpal bones 0.663984877528097 1.204972287266929 0.2282140004100035 1.0 0.4933745667215971 6 Q9NR45 1 +Carpal bone hypoplasia 0.663984877528097 1.204972287266929 0.2282140004100035 1.0 0.4933745667215971 6 Q9NR45 1 +Clubbing of toes 0.6650248883547961 1.200708577642553 0.2298642656360148 1.0 0.4951759614165737 5 Q9BXW9,Q9NVI1 2 +Squared iliac bones 0.5202724618877612 1.1994784896512252 0.2303419438980238 1.0 0.4957002403126119 2 P36776 1 +Enchondroma 0.6293720989016738 1.1977684054991735 0.2310071902831865 1.0 0.4962444539545244 8 O75874,P48735 2 +Reduced protein s activity 0.5920605841697899 1.1971397046790282 0.2312521064675499 1.0 0.4962444539545244 3 P34949 1 +Abnormality of the protein c anticoagulant pathway 0.5920605841697899 1.1971397046790282 0.2312521064675499 1.0 0.4962444539545244 3 P34949 1 +Reduced protein c activity 0.5920605841697899 1.1971397046790282 0.2312521064675499 1.0 0.4962444539545244 3 P34949 1 +Malignant neoplasm of the central nervous system 0.4402893552362524 1.1952160382328605 0.2320026339093712 1.0 0.4968397303487065 21 O75874,Q15555,P48735,Q12824 4 +Abnormality of small intestinal villus morphology 0.645670610405806 1.194153638161699 0.232417874704772 1.0 0.4971238529289958 7 Q13277,P34949,Q6PGP7 3 +Abnormal metabolism 0.3561963647986725 1.1933195421295242 0.2327442518756797 1.0 0.4975608593661298 50 Q9P2R7,Q14746,P51571,Q9UP83,Q96AA3,P34949,Q9NP73,P46783,Q9Y487,P41440 10 +Focal dystonia 0.4395744539907205 1.1902364232460076 0.2339534810891543 1.0 0.4985178410389956 21 Q99720 1 +Increased serum pyruvate 0.3877194817674917 1.1862743806948033 0.2355139606029899 1.0 0.5000161251353858 36 O43676,Q96RR1,P03886,Q70HW3,Q96CU9,O96000,O95831 7 +Bronchiectasis 0.4490953612095006 1.1860826945183731 0.2355896439707274 1.0 0.5000161251353858 19 Q9NVR5,Q13432 2 +Airway obstruction 0.4860108987720637 1.1859507845670016 0.2356417359140263 1.0 0.5000161251353858 15 P09601,Q9NVR5 2 +Abnormality of the forehead 0.2502471262514704 1.1858093385456343 0.2356976027571193 1.0 0.5000161251353858 290 P13073,Q16625,Q15392,Q03164,Q9Y619,Q9Y487,Q10713,O60762,Q9NR45,Q8NC96,Q9NP72,Q96J42,O75381,Q9BXW9,O96011,Q9UM00,Q9BZK7,Q13868,P46783,P51812,O75845,Q6PGP7,Q68CP9,Q96DX4,O75648,Q13586,Q6P2C8,Q96N67,O60566,Q96J02,O15160,Q96F07,O95831,Q8N3U4,P83436,Q15021,O15228,Q8TD30,Q14739,Q71SY5,Q9UP83,O43791,P52732,Q7LGA3,Q13555,Q12824,Q9NSE4 47 +Abnormality of bone mineral density 0.3030245107489609 1.185801380331971 0.2357007462860516 1.0 0.5000161251353858 129 Q15392,Q96RR1,P51809,Q96HY6,Q9Y487,P06132,Q9BXW9,Q96AY3,Q13126,Q9H1A4,Q32P28,Q9NWM8,Q9HC07,P57678,O75845,Q96DX4,O95831,O15228,Q14739,Q9NSE4 20 +Purpura 0.4388687491020663 1.1853224440175776 0.2358899828248652 1.0 0.5000161251353858 21 Q16625,P38435,Q9BZK7 3 +Short ribs 0.5596505658487994 1.183352938252319 0.2366693004823976 1.0 0.5000161251353858 11 Q14739,Q96HY6,Q15427 3 +Prominent antitragus 0.5170288679857176 1.1826377689238168 0.2369527372312863 1.0 0.5000161251353858 2 Q92643 1 +Congenital contracture 0.3744777921182324 1.1823931149715057 0.2370497538252527 1.0 0.5000161251353858 42 P11310 1 +Abnormality of the kidney 0.2568952447557834 1.1818986757493963 0.2372459075041848 1.0 0.5000161251353858 317 Q9NPL8,Q16625,Q15392,P61619,Q5JRA6,O43772,Q03164,P51809,P03886,Q10713,Q8IY17,P00846,Q9NP72,Q96J42,O43676,O75381,Q9BXW9,O96011,Q9UM00,Q9BZK7,P46783,P09601,P57678,Q9H9B1,P11802,O75845,Q6PGP7,Q68CP9,Q9NZ08,P51571,Q13277,O60566,Q07812,Q9BQP7,Q14145,Q9NQH7,P83436,Q9Y5K6,Q71SY5,P50416,O43819,O43791,Q96CU9,Q15427,Q7LGA3,O96000,Q12824 47 +Abnormal left atrium morphology 0.5885788449059144 1.181169854586621 0.2375352541482009 1.0 0.5000161251353858 3 Q14315,P13807 2 +Left atrial enlargement 0.5885788449059144 1.181169854586621 0.2375352541482009 1.0 0.5000161251353858 3 Q14315,P13807 2 +Abnormality of the neck 0.3028302208830973 1.1796582940127402 0.2381361477479422 1.0 0.5010481882481088 159 Q99720,Q03164,Q15555,Q96HY6,Q9Y487,Q9NR45,O75381,Q99575,O96011,Q9UM00,Q9BZK7,Q96AA3,P46783,Q96DX4,O95831,P83436,Q14739,Q9UP83,O96000 19 +Chorea 0.339206072277458 1.1785274318019614 0.2385864028509061 1.0 0.501762490675304 80 Q99720,Q9UBB6,O43791,P03886,O43819,Q96RL7,P00846,Q86VD7,Q9P0J0,Q96IX5 10 +Flared metaphysis 0.6249347828102321 1.1778247228210923 0.2388664903523198 1.0 0.5021184228751783 8 Q9NR45,Q96HY6 2 +Abnormal circulating gonadotropin concentration 0.4829260335112612 1.167466537274718 0.243022014290327 1.0 0.5084940991848412 15 Q12824,Q8IY17 2 +Abnormality of the vertebral endplates 0.654539864400465 1.1655147572417155 0.2438106902682677 1.0 0.5099087843560725 6 Q9NR45,O15228 2 +Brain neoplasm 0.5128121959130622 1.160759354276354 0.2457397766483353 1.0 0.5122877074169163 2 Q07864 1 +Peripheral hypermyelination 0.5832594721653026 1.1567894906575178 0.2473583765745917 1.0 0.5144781661537651 3 Q13614 1 +Abnormal muscle glycogen content 0.6540846079603276 1.1554385783840229 0.2479108714974194 1.0 0.5151542421483073 5 Q9BUK6 1 +Scotoma 0.51368968823033 1.153342997241234 0.2487696283744906 1.0 0.5167017040515556 13 P00846,P03886,Q9H6K4 3 +Low set posteriorly rotated ears 0.3382637973785187 1.152664365163094 0.2490481732088476 1.0 0.5167284891245663 66 Q68CP9,O75381,Q15392,O96011,P98175,Q9UM00,Q15555,O60566,Q96J02,Q15427,Q6DKJ4,Q10713,Q8IY17,Q9NP72,O96028,Q96J42 16 +Minicore myopathy 0.581440622972105 1.1484589407588115 0.2507791537662758 1.0 0.5182616635772032 3 P51114,Q9Y281 2 +Quadriceps muscle weakness 0.6529262710180541 1.1437557152699709 0.2527249601420775 1.0 0.5208571744511425 4 P12235,Q96RR1 2 +Increased csf lactate 0.3443669103252108 1.140324546392666 0.2541511150541304 1.0 0.5230824857770154 56 O43676,P13073,P03886,O43819,Q96CU9,O96000,P00846,O95831,Q9P0J0 9 +Semilobar holoprosencephaly 0.6510985318313461 1.1362726221815247 0.2558424851334349 1.0 0.5263244585170118 4 Q8N3U4 1 +Abnormal urinary color 0.6508489852253592 1.1352511641616532 0.2562700976446295 1.0 0.52672574515888 4 P06132 1 +Abnormal echocardiogram 0.6504381694255149 1.1335697136838423 0.2569750831471018 1.0 0.5276958869702499 4 P12235,Q969Y2,Q96RR1 3 +Abnormality of globe size 0.3437041137871466 1.1332337811122484 0.257116091530909 1.0 0.527746214152704 56 Q9H7D7,Q15555,Q9NP72,Q96J42,Q9BXW9,P38398,Q9BZK7,Q6W2J9,P61586,Q12797,O60566,Q96N67,O15160,Q9BUK6,P53701,Q71SY5,Q9NVI1,P52732,Q96CW1 19 +Abnormality of the ribs 0.3419442971973194 1.1324457442983809 0.2574470823034853 1.0 0.5281862693998136 59 Q14739,P50570,Q03164,Q9UM00,Q9Y619,Q32P28,Q15427,Q96HY6,O14802,O95831,O96028 11 +Wormian bones 0.4460984367453117 1.1317467160576669 0.2577409350732846 1.0 0.5285353941968784 18 O95831,Q9Y487,Q32P28 3 +Exostoses 0.649350165799871 1.1291173188495736 0.2588483463139288 1.0 0.5298612782657468 4 P48735 1 +Conical tooth 0.6304585039926572 1.1284018968106813 0.2591502270904833 1.0 0.5302396245347287 7 Q9H1A4,Q9Y487,P17252,P61586,Q92925 5 +Slanting of the palpebral fissure 0.2912322953691418 1.12806634999079 0.2592918990200274 1.0 0.5302899785827199 182 Q15392,Q03164,Q15555,Q9NP73,Q9Y487,O60762,Q8NC96,O75381,Q9BXW9,P78318,O96011,Q9UM00,Q13868,Q6DKJ4,P51812,Q9H553,Q9H9B1,Q15907,Q05086,O75845,Q6PGP7,Q68CP9,Q05639,P80404,O75648,O60566,Q6P2C8,O15160,O14802,Q96F07,P83436,P61981,Q71SY5,P42345,O43791,P52732,Q15427,Q7LGA3,Q9Y5P4,O96028 40 +Congenital malformation of the left heart 0.6442973128755584 1.1228091605680004 0.2615185539714966 1.0 0.5331331875645788 6 O43791,O14802,Q8N3U4 3 +Abnormal dermatoglyphics 0.332479984058821 1.1227783015490531 0.261531663047593 1.0 0.5331331875645788 69 O75381,O96011,Q71SY5,P42345,Q9BZK7,Q96J02,Q6DKJ4,Q9Y487,P51812,O96028,Q8IY17,Q9H9B1,Q15907 13 +Protein losing enteropathy 0.5757360212197705 1.122353500192698 0.2617121670968831 1.0 0.5331331875645788 3 P34949 1 +Aplasia hypoplasia of the patella 0.6288322928255429 1.1213873708703008 0.2621230095107496 1.0 0.5334309223197196 7 Q9H1A4,Q96AY3 2 +Neoplasm of the adrenal cortex 0.6455599952699407 1.1202321537740052 0.2626148453335937 1.0 0.5339520867868849 5 P48735 1 +Ocular albinism 0.574951330305001 1.1187654883963971 0.2632401984754788 1.0 0.5349834450847551 3 Q96T58,O00203 2 +Duodenal atresia 0.6428496122343528 1.116781649486286 0.2640876968341588 1.0 0.5364352396721638 6 Q8N3U4,O60566,Q9Y2W2 3 +Right ventricular hypertrophy 0.5734796100104472 1.1120380710064497 0.266121781679461 1.0 0.5396292171029357 3 Q9H267 1 +Aplasia hypoplasia involving bones of the upper limbs 0.2998480746386844 1.1100642491576802 0.2669713414619075 1.0 0.5408676998311452 140 P13073,Q03164,Q15555,Q9Y619,Q9NP73,O60762,Q9NR45,Q9BXW9,Q96AY3,Q9H1A4,Q9BZK7,P38435,Q32P28,P46783,P51812,Q68CP9,Q96DX4,O14802,O95831,O15228,Q14739,P42345,Q15427,Q13555,Q12824 25 +Elevated urinary carboxylic acid 0.640621927725057 1.107511336682533 0.2680729136037756 1.0 0.5423717278361337 6 P11310 1 +Organic aciduria 0.3719857217339023 1.1064033727141154 0.2685519663523448 1.0 0.5430983962393401 39 P11310,P48735,O43772 3 +Coma 0.3814365507597247 1.1041727399391972 0.2695182123225608 1.0 0.5445662363163248 35 Q13423,P11310,O43772 3 +Long palm 0.5014596172559079 1.1019642344301896 0.2704772208560722 1.0 0.5452878551303991 2 P16435 1 +Hyperthyroidism 0.5854315417057975 1.101102750226714 0.2708519402100229 1.0 0.5458003955299838 9 Q9BUK6,O14802,Q96RR1 3 +Abnormal metatarsal morphology 0.4303329257692148 1.0973405083989096 0.2724925691782902 1.0 0.5481435057799874 20 Q15392 1 +Blepharophimosis 0.3515127057700997 1.0970495846834762 0.2726197171130931 1.0 0.5481435057799874 48 Q9BXW9,Q03164,Q15555,Q13724,Q9Y619,Q9BZK7,O75648,Q6P2C8,Q7LGA3,P61586 10 +Progressive spastic paraplegia 0.3856900430188154 1.0913146348076743 0.2751344602942556 1.0 0.5509987202179389 33 P00846,Q9P0J0,Q96CU9,Q8IY17 4 +Poikilocytosis 0.4698071300850681 1.0891267144068777 0.2760980108026662 1.0 0.552243261465593 15 Q96RL7,P41440 2 +Abnormal location of ears 0.2798126121453588 1.0869686232623412 0.2770506766395226 1.0 0.5534570311023836 226 Q16625,Q15392,Q03164,Q15555,Q9Y619,Q9NP73,Q9Y487,Q10713,Q8IY17,Q96J42,O75381,Q9BXW9,O96011,Q9UM00,Q9BZK7,Q13868,P46783,Q9HC07,Q96DX4,O60566,Q6P2C8,Q96J02,O95831,Q8N3U4,P83436,Q8TD30,Q14739,Q71SY5,Q9UP83,O43791,Q15427,Q7LGA3,Q13555 33 +Depletion of mitochondrial dna in muscle tissue 0.6390097252740063 1.086862302006225 0.2770976688223383 1.0 0.5534570311023836 4 Q96RR1 1 +Wide nasal ridge 0.6373972172105278 1.086591870681224 0.2772172193314146 1.0 0.5534570311023836 5 Q9BZK7 1 +Multiple cafe au lait spots 0.5209225186710802 1.0844543306871328 0.2781634055438449 1.0 0.5539355683101713 12 Q9BXW9,Q9NVI1,P38398,O60566,P43246 5 +High anterior hairline 0.4198877100688733 1.0844534469909748 0.2781637971676975 1.0 0.5539355683101713 22 Q8N3U4,Q9BZK7,O96028,Q7LGA3 4 +Poikiloderma 0.6383469950374687 1.08415827350599 0.2782946289399806 1.0 0.5539355683101713 4 Q9H1A4 1 +Abnormal vitreous humor morphology 0.6201140518709889 1.08384131526508 0.2784351631439867 1.0 0.5539355683101713 7 P53701,P36405,P04439,Q6W2J9 4 +Scarring alopecia of scalp 0.5668468667184741 1.0817550731262189 0.2793613744685215 1.0 0.5548036064631313 3 P06132 1 +Abnormality of coordination 0.2520381040907931 1.076890441285418 0.2815292139492547 1.0 0.5583744917645025 314 Q9NPL8,Q99720,P11310,Q96RR1,P03886,Q8WWI5,Q9Y487,Q8IY17,P00846,Q8NC96,P41440,Q9NR45,Q02218,O43676,O75381,Q6P4A7,O96011,P00374,O14653,Q96RL7,Q96IX5,Q05086,Q9P2R7,Q13586,Q96F07,Q9BUK6,O95831,Q86VD7,Q9C0E8,Q9UP83,P07196,O43819,Q96CU9,O96000,Q9H6K4,Q9P0J0,Q12824 37 +Ventricular arrhythmia 0.3808131583257202 1.0738646029399834 0.2828833700975903 1.0 0.5608147337164482 34 P00846,P03886,O43772 3 +Aphasia 0.3741456308773019 1.0689451019127745 0.2850944072954469 1.0 0.5635834290293338 36 Q9H9P8,P17480,P03886,O75648,Q6P2C8,Q7LGA3,P53701,Q9H9B1,O96008 9 +Abnormal bone structure 0.2944498867068748 1.0688199211011842 0.2851508210453053 1.0 0.5635834290293338 166 Q15392,Q96RR1,P51809,Q96HY6,Q9Y487,P06132,O75381,Q96AY3,Q9BXW9,P48735,Q13126,O96011,Q9H1A4,P38435,Q32P28,Q9NWM8,Q9HC07,P57678,O75845,Q96DX4,Q9NUQ7,O95831,O15228,Q14739,O75874,Q9NSE4 26 +Headache 0.3315080175383747 1.065433669370966 0.2866797271882586 1.0 0.5656181028583674 65 Q9Y5K6,Q9NZ08,O96011,Q96RR1,O43791,P03886,Q13586,P00846,Q12824 9 +Poor eye contact 0.3617325436124357 1.0644182696157949 0.2871392610603851 1.0 0.566078677777815 42 O43676,Q96RR1,P03886,Q96CU9,Q96N67,O96000,Q9P0J0 7 +Acanthocytosis 0.6317477148213013 1.0633583970410472 0.2876194518138493 1.0 0.5664852681377118 5 Q96RL7 1 +Abnormality of the cerebral subcortex 0.2601119587935593 1.0621879151426967 0.2881503849464555 1.0 0.566991760599409 357 Q9NZ01,Q15392,P49419,Q96RR1,Q03164,P03886,Q15555,Q9Y619,Q5BJH7,Q8WWI5,Q10713,P00846,Q8NC96,Q9NR45,Q96J42,Q9BXW9,Q9H9P8,Q9UBB6,Q9UM00,Q96RL7,Q96AA3,Q9HC07,Q05086,Q9P2R7,Q96DX4,Q9NUQ7,P51571,Q14746,Q13724,O75648,O60566,Q6P2C8,Q96N67,Q96F07,Q9BUK6,O95831,P53701,Q8N3U4,P83436,Q8TD30,Q96PU5,Q96B26,Q71SY5,Q9C0E8,Q9UP83,O43819,Q96CU9,Q7LGA3,Q96D71,O60313,Q9P0J0,Q12824 52 +Generalized dystonia 0.4933506325007988 1.0600967177669345 0.2891006008735122 1.0 0.5676747819492892 2 P42704 1 +Easy fatigability 0.420406985168947 1.0574708983069154 0.2902967294182317 1.0 0.5689207092363362 21 P50570,Q96RR1,Q13586,Q9NWM8,Q9BQP7,Q9H553 6 +Decreased fertility in males 0.553460116660346 1.0573254897188666 0.2903630639634458 1.0 0.5689207092363362 10 Q9BXW9,Q9NVR5,Q9NVI1,P51809 4 +Peripheral demyelination 0.4390776625347864 1.0570286622495009 0.2904985065752623 1.0 0.5689400063925372 17 P03886 1 +Failure to thrive 0.2465454350457678 1.0522293940054424 0.292694316618675 1.0 0.5719815774646121 296 P13073,Q16625,Q15392,Q96RR1,Q03164,P03886,Q9NRW7,Q9Y487,P00846,Q8NC96,O43676,O75381,Q9BZK7,Q9HC07,Q9P2R7,P51571,Q13423,Q96F07,Q8N3U4,P83436,O15228,Q8TD30,Q14739,Q96B26,O43791,O43819,Q96CU9,P34949,O96000,P28070,Q9P0J0 31 +Developmental cataract 0.3368012176097953 1.0494816601255683 0.2939564917648147 1.0 0.5732341402043095 53 O96011,Q71SY5,Q9H1A4,P03886,P46783,O00400,Q9NP72,Q9H9B1,O94979,Q9NSE4 10 +Glomerulonephritis 0.4506533644806696 1.0487783525537175 0.2942801428615915 1.0 0.5733716331883913 16 Q8NFH4,P52565,Q03252,Q8N1F7,P53621,Q9Y5K6,P49327,Q9P2R3,Q8WUM0,Q14C86,Q12769 11 +Abnormality of female external genitalia 0.3747843229313834 1.0478696326370087 0.2946986751243186 1.0 0.5734253725172923 35 O75381,Q15392,O96011,P51809,Q9Y619,P53701 6 +Abnormality of thyroid physiology 0.3277936475932532 1.0476718823113853 0.2947898064969458 1.0 0.5734253725172923 75 Q96RR1,Q9H1A4,O43791,P03886,Q13724,O60566,P34949,Q96J02,Q13868,Q13423,O60313,Q9BUK6,Q8N3U4,Q12824,Q6PGP7 15 +Retinal degeneration 0.3366219863980004 1.0455739528938628 0.295757780320061 1.0 0.5735273958336754 52 P04439,Q05639,O75648,Q6P2C8,Q7LGA3,Q9UG56,Q10713,Q96F07,Q8IY17,Q8NC96,O60313 11 +Hydroureter 0.5135359940342232 1.0455667969303168 0.295761085682114 1.0 0.5735273958336754 12 Q9BXW9,Q9NVI1,P38398,Q7LGA3,Q6W2J9 5 +Broad phalanx of the toes 0.6256340134728119 1.0453107623419835 0.2958793651353861 1.0 0.5735273958336754 6 Q71SY5,Q7LGA3 2 +Epicanthus 0.2947989919102359 1.040997763334961 0.2978765862967267 1.0 0.5766585196257147 157 Q15392,Q03164,Q15555,Q9Y487,Q10713,Q8IY17,Q9NR45,O75381,Q9BXW9,O96011,Q9UBB6,Q9UM00,P46783,P51812,O75845,Q05086,Q96DX4,O60566,Q8N3U4,Q71SY5,O43791,P52732,Q7LGA3,Q9Y5P4 24 +Tapered finger 0.3705733835056244 1.0383599356271171 0.2991025146008468 1.0 0.5782903931463236 36 Q03164,O43791,Q15555,P51812,Q9NSE4 5 +Abnormal blood transition element cation concentration 0.4923501731620794 1.035780453538376 0.3003045785199976 1.0 0.578721102266506 13 Q14746,O43819,P35670,P28288,Q9Y487,Q6PGP7 6 +Abnormality of the auditory canal 0.4172371308623399 1.0356888852004118 0.3003473093661271 1.0 0.578721102266506 21 P08754,Q9Y619,Q15427,Q9Y5N6,O60216,P21281,O96028,P55011 8 +Exertional dyspnea 0.4211250959141236 1.034970895296578 0.3006825035997 1.0 0.5788955243894577 20 P11310,Q9BZK7 2 +Broad palm 0.5711718094549781 1.0347793281873228 0.3007719789870888 1.0 0.5788955243894577 9 O95831,Q14739,Q9BZK7 3 +Peripheral axonal degeneration 0.3278830884196371 1.0346739485941026 0.3008212062721376 1.0 0.5788955243894577 66 Q96RR1,Q9BQT8,P07196,Q96RL7,P03886,Q8IY17,O95831,P00846,P41440,O60313,O15269 11 +Abnormal facial expression 0.381151154458049 1.0334842299612996 0.3013773467860183 1.0 0.5796456329726931 32 Q86U42,P49419,Q05086,Q96RR1 4 +Loss of ability to walk 0.4721627280106179 1.0332927651448514 0.301466911983149 1.0 0.5796456329726931 14 P00846,Q96RR1 2 +Cerebral white matter atrophy 0.412406239028212 1.0320703059073886 0.3020391831527591 1.0 0.5804475387987652 22 Q9UP83,Q9H9P8 2 +Neonatal respiratory distress 0.4077023085899122 1.0314801586312272 0.30231570800811 1.0 0.5805384303843741 23 O43791,Q9NVR5,P49419 3 +Underdeveloped supraorbital ridges 0.5103945225902624 1.0290764693023406 0.30344374250781 1.0 0.5822109926134601 12 O75381,O96011,O43791,P52732,P98175,Q6PGP7 6 +Posteriorly rotated ears 0.3157807678837729 1.0271167663965912 0.3043654846301797 1.0 0.5827766323350506 106 Q15392,Q15555,Q9Y619,Q10713,Q8IY17,Q9NP72,Q96J42,O75381,O96011,Q9UM00,Q9BZK7,Q13868,Q9HC07,Q68CP9,O60566,Q96J02,Q9UP83,O43791,Q15427,Q7LGA3 20 +Hydrocephalus 0.325569118230621 1.0270821336877722 0.304381790751596 1.0 0.5827766323350506 73 Q9BXW9,Q15392,O60566,Q8N3U4,Q9NP73,Q15427,Q9NVR5,P53701,Q02218,Q96J42,Q12824 11 +Osteopenia 0.3237828282560573 1.0219908537935216 0.3067852292968234 1.0 0.5856575601938864 69 Q96AY3,Q96DX4,Q9H1A4,Q32P28,Q9NWM8,P06132,Q9Y487,P57678,Q9NSE4,O15228 10 +Congenital nystagmus 0.4292105447169879 1.0219776538234644 0.3067914768962676 1.0 0.5856575601938864 18 P00846,O75648,Q6P2C8 3 +Abnormality of corneal size 0.3624462703416082 1.0216482968075646 0.3069473901967186 1.0 0.5857083730375464 39 Q71SY5,P52732,Q15555,Q9BZK7,Q9NWM8,Q96J42,O75845 7 +Choroid plexus carcinoma 0.5527389509358431 1.0175818316280596 0.3088767251329023 1.0 0.5883984713423244 3 Q12824 1 +Abnormal synaptic transmission at the neuromuscular junction 0.4004648579043751 1.0148380431918502 0.310183035886455 1.0 0.5896471475306929 24 P11310,Q92804 2 +Feeding difficulties in infancy 0.292531640607467 1.0129078271443992 0.3111041894008646 1.0 0.5906546429111135 160 Q9NPL8,Q99720,Q9Y619,Q5BJH7,Q9Y487,Q10713,O60762,O75381,P17480,O96011,Q05086,Q9P2R7,Q13724,O75648,O60566,Q96J02,O95831,Q8N3U4,Q8TD30,Q9UP83,P50416,O43819,O43791,O95363,O60313 25 +Venous thrombosis 0.4876677864334012 1.0101714115212177 0.3124131735152127 1.0 0.5923080953379166 13 O75874,P48735,Q9NZ08 3 +Generalized onset motor seizure 0.3327382011160124 1.0099409635478176 0.3125235753796191 1.0 0.5923080953379166 54 P49419,Q9C0E8,Q14746,P03886,P00846,Q05086 6 +Preaxial polydactyly 0.5253567471134264 1.0095821101253128 0.312695544250654 1.0 0.5923080953379166 11 Q9BXW9,Q96J42 2 +Abnormal nervous system electrophysiology 0.2888841688225336 1.0086474714404512 0.313143732049681 1.0 0.5925401446052861 172 Q99720,P13073,Q9NZ01,P49419,P03886,Q9Y619,Q9NP73,Q8WWI5,O60762,Q13614,Q8NC96,O75381,O96011,Q9UBB6,Q96RL7,Q05086,O15269,Q9P2R7,Q9NUQ7,Q13724,Q96N67,Q96F07,O95831,Q71SY5,P07196,O95363,O60313,Q9NSE4 28 +Anencephaly 0.4864657990191395 1.003610743478775 0.3155662741105316 1.0 0.5948877327177313 13 Q96J42 1 +Abnormal enchondral ossification 0.3933374131506437 1.0020812964184758 0.3163043304250441 1.0 0.5957832086592307 26 O75381,Q14739,O96011,Q9NUQ7,P38435,Q9Y619,Q96HY6,O96028 8 +Gait disturbance 0.2465999942894718 0.9967998222538322 0.3188616845698289 1.0 0.5993541207889315 305 Q99720,Q96RR1,Q03164,P03886,Q9Y619,Q10713,Q8IY17,P00846,Q8NC96,P41440,Q96AY3,P17480,P18887,O14653,Q96RL7,P51812,P57678,Q86U42,Q05086,Q9BRK0,O15269,Q9P2R7,Q9NZ08,Q96DX4,Q9NUQ7,Q9BQT8,Q8WXH0,O75648,Q6P2C8,Q96N67,Q96F07,Q9BUK6,O95831,Q8N3U4,Q9Y5P4,Q8TD30,Q71SY5,Q9C0E8,P07196,O43819,Q96CU9,Q7LGA3,O95363,Q96D71,Q9H6K4,O60313,Q12824 47 +Generalized tonic seizure 0.4418407142077424 0.9949189081936513 0.3197757058451822 1.0 0.6005737759032651 16 P67870,Q00610,Q05639,Q14746,Q96N67,O60762,Q969N2,P43034 8 +Myopathy 0.3195267554762043 0.9943535558633362 0.320050770770111 1.0 0.6007870469467264 97 O43676,P11310,Q13126,Q96RR1,P07196,Q8WXH0,P03886,Q96RL7,Q13586,Q9NWM8,Q9BQP7,Q9BUK6,P00846,Q8NFF5,Q86U42 15 +Abnormality of long bone morphology 0.2888729498512038 0.9911884854455152 0.3215935520229367 1.0 0.6029879100430063 169 Q5JRA6,Q6NUQ1,Q96HY6,Q9Y487,Q9NR45,Q96J42,O75381,Q96AY3,Q9BXW9,P48735,Q99575,Q13126,O96011,Q9H1A4,P38435,Q32P28,Q13868,Q9HC07,Q96DX4,Q9NUQ7,O75648,Q6P2C8,Q96J02,O95831,O15228,Q14739,Q71SY5,Q9UP83,O75874,Q15427,Q7LGA3,Q9NSE4 32 +Abnormal circulating androgen level 0.4839598563900343 0.9899513470243024 0.3221979002299828 1.0 0.6034966682239897 13 Q13423,O14802,Q12824,P51809 4 +Macular purpura 0.4408873118846936 0.9891153218311696 0.3226067219974635 1.0 0.6036383521885625 16 Q16625,Q9BZK7 2 +Abnormal posterior segment imaging 0.6148356500111489 0.988645733851559 0.3228365019146646 1.0 0.6038188908643396 4 P50213,P04439 2 +Myalgia 0.3569570508832918 0.9876093645854804 0.3233439982111314 1.0 0.6038676288176008 40 Q14739,P11310,Q9NZ08,P50570,Q96RR1,Q14315,Q13586,O14802,Q9BUK6,O60313 10 +Corneal dystrophy 0.6132164198799535 0.9875036866543728 0.3233957764926047 1.0 0.6038676288176008 5 Q13868,Q9Y5Z9 2 +Recurrent acute respiratory tract infection 0.5459782772114636 0.9869716595462916 0.3236565321990934 1.0 0.6041055174544264 3 Q03518 1 +Hypermetric saccades 0.5458329782160618 0.9863149615580408 0.3239785801226915 1.0 0.6044575650559278 3 P18887 1 +Parkinsonism 0.3813708109206561 0.9859406166497544 0.324162254082097 1.0 0.6045512601860433 29 Q99720,Q96RR1 2 +Abnormality of pelvic girdle bone morphology 0.2918954508974162 0.9840726493461398 0.3250797936682974 1.0 0.6053941403993487 142 Q6NUQ1,Q9Y619,Q96HY6,Q9Y487,Q9NR45,Q9BXW9,Q96AY3,Q99575,P51812,P57678,Q8IZA0,Q9NQT5,Q96DX4,Q9NUQ7,O75648,Q6P2C8,O14802,O95831,Q8N3U4,O15228,Q14739,Q15427,Q7LGA3,O95363,O96028,O94979,Q9NSE4 27 +Round face 0.4096436171155369 0.9837697823420783 0.3252287200269292 1.0 0.6053941403993487 21 Q03164 1 +Cortical dysplasia 0.3845873276654058 0.9837460836165204 0.3252403750830166 1.0 0.6053941403993487 28 Q96PU5,Q9NZ01,Q9NUQ7,Q9UBB6,Q96IZ7,Q71SY5,P42345,Q8WUM0,Q96C86,Q2M389,O00571,Q08J23,P08243,P55011 14 +Abnormal mitochondria in muscle tissue 0.4009486200876369 0.9836606076354434 0.3252824145103785 1.0 0.6053941403993487 23 O43676,O96000,P03886,Q96CU9 4 +Lethargy 0.3228149049867473 0.982878564345406 0.3256672089252272 1.0 0.6058613784112031 83 O43676,P11310,Q96RR1,O43772,P50416,P03886,Q96CU9,O96000,Q96IX5,Q8N3U4 10 +High forehead 0.3198602918943147 0.9802807278715456 0.3269475651111126 1.0 0.6070098375383954 94 O75381,Q14739,O96011,Q71SY5,Q03164,O75648,Q9BZK7,Q6P2C8,Q13586,O60566,Q13868,Q7LGA3,Q96F07,Q8NC96,O15228 15 +Enlarged posterior fossa 0.3374312171977913 0.9802666219796442 0.3269545261796214 1.0 0.6070098375383954 49 Q9NPL8,Q68CP9,P49419,O60566,Q9Y487,Q10713,Q96J42,Q12824 8 +Abnormal peripheral nervous system morphology 0.2916741686773598 0.9796714192455604 0.3272483384664217 1.0 0.6073064208328105 150 Q99720,Q96RR1,P03886,Q9Y619,Q9NP73,Q13614,Q8IY17,P00846,P41440,O75381,P17480,O96011,Q96RL7,Q9BZK7,Q86U42,O15269,Q9P2R7,Q9BQT8,Q9BQP7,O95831,Q71SY5,P07196,O43819,O60313,Q12824 25 +Dolichocephaly 0.3665167133088211 0.9785694075161436 0.3277927812666259 1.0 0.6078445613353721 35 Q03164,O75381,O96011,Q9BXW9 4 +Bone spicule pigmentation of the retina 0.5947972691921818 0.975551544412962 0.3292867468389771 1.0 0.60946126691089 7 Q9UG56,P36405,Q15555,P50213 4 +Disinhibition 0.3297769142674251 0.9754088146129598 0.3293575130180186 1.0 0.60946126691089 52 Q9NZ01,P61981,P17480,Q9NUQ7,Q9UBB6,Q71SY5,Q05639,Q96RL7,Q14203,Q96C86,P35637,Q96F07,Q8NC96,Q08J23,P55011,Q96QK1,O96008 17 +Abnormal circulating sex hormone concentration 0.4170367531009051 0.9734348018015364 0.3303372492839558 1.0 0.610013293251508 19 Q13423,O14802,Q12824,P51809 4 +Lymphoproliferative disorder 0.6110091123375794 0.9731927118862176 0.3304575323706844 1.0 0.610013293251508 4 P17812 1 +Polyneuropathy 0.4118729271721523 0.9728008016936548 0.3306523141819633 1.0 0.6101242294274108 20 P00846,P03886 2 +Abnormal shape of the palpebral fissure 0.5179429298383478 0.9724273338161922 0.3308379991618628 1.0 0.61021829649969 11 Q9BXW9,Q9NVI1,P38398,P55795,Q9H9B1 5 +Hypoplastic heart 0.6092271281620091 0.9712590097896828 0.331419315228677 1.0 0.6110417167219809 5 O43791,Q8N3U4 2 +Abnormality of lower limb metaphyses 0.6089701595889059 0.970213787597914 0.3319399396140454 1.0 0.6115038334492175 5 O95831 1 +Generalized myoclonic seizure 0.3531988567160369 0.9696713563830904 0.3322103323918672 1.0 0.6117531730630726 41 P00846,P03886,P49419 3 +Abnormal nasal base 0.498748528195566 0.9682398690564122 0.3329245876649356 1.0 0.612399145342355 12 Q13868,Q12824 2 +Central nervous system cyst 0.3290556394585649 0.9680707254146248 0.3330090490638848 1.0 0.612399145342355 52 P00846,Q9Y487,Q9NQT5,Q12824 4 +Severe expressive language delay 0.6094793860526925 0.9670235910959584 0.3335322404752574 1.0 0.6124154657564911 4 Q96DX4 1 +Biliary cirrhosis 0.5924761084405107 0.9656922989591098 0.3341981741542974 1.0 0.6124154657564911 7 Q14739,P09601 2 +Reduced antithrombin iii activity 0.6091173494179696 0.9655642933001768 0.3342622497851364 1.0 0.6124154657564911 4 P34949 1 +Constriction of peripheral visual field 0.4107217857030139 0.9651066310690594 0.3344914059685859 1.0 0.6124154657564911 20 P00846,O75381,Q15555,O96011 4 +Productive cough 0.5560451614234574 0.964953505855629 0.3345680999400131 1.0 0.6124154657564911 9 Q9BZK7 1 +Furrowed tongue 0.5771190895834065 0.964775703058634 0.3346571680937393 1.0 0.6124154657564911 8 Q96J42 1 +Short digit 0.2907528756322959 0.9646810807228018 0.3347045742343293 1.0 0.6124154657564911 149 P13073,Q5JRA6,Q03164,Q9NP73,Q8IY17,Q9BXW9,Q99575,Q9BZK7,P38435,Q13868,P46783,P51812,Q9H9B1,P61586,Q96DX4,O75648,Q6P2C8,O95831,Q14739,Q15427,Q7LGA3,Q13555,Q12824,Q9NSE4 24 +Abnormality of hepatobiliary system physiology 0.3206351693554689 0.9644120636920052 0.3348393764036559 1.0 0.6124154657564911 75 O75381,Q16625,P11310,O96011,O43772,Q6NUQ1,Q14746,P03886,O75648,P50416,O43819,P34949,P08574,P00846,P83436,O75845 16 +Cubitus valgus 0.5341563343137893 0.9640144540990182 0.3350386792770008 1.0 0.6124154657564911 10 Q99575 1 +Hyperventilation 0.6056322829495959 0.962900900805082 0.3355972574859978 1.0 0.6124154657564911 6 P03886 1 +Focal t2 hyperintense brainstem lesion 0.4100433308540353 0.960576483753387 0.3367651574710364 1.0 0.6134081879146743 20 O43676,O96000,P03886,Q96CU9 4 +Intestinal atresia 0.5544493928403206 0.9576258080560895 0.3382514805060896 1.0 0.6155092001883956 9 Q8N3U4,O60566,Q9Y2W2 3 +Contractures of the joints of the upper limbs 0.3192123187517863 0.9572083108203886 0.3384621231058042 1.0 0.6155092001883956 72 Q99720,Q96AY3,Q15392,Q71SY5,P07196,Q9UP83,Q8WXH0,Q9Y619,Q7LGA3,Q8IZA0 10 +Limited elbow extension 0.4580423147441245 0.95282734050733 0.3406775592432054 1.0 0.6181270043727719 14 Q96DX4,Q15427,Q9H6K4 3 +Recurrent sinopulmonary infections 0.5886424898406939 0.949439192048468 0.3423972852013925 1.0 0.6191855097653924 7 Q9NVR5 1 +Exercise induced myalgia 0.5308102583740157 0.9479596507229264 0.3431499957420345 1.0 0.6198510312068498 10 P11310 1 +Adrenal hyperplasia 0.6046738072054567 0.9476769177267976 0.3432939552222769 1.0 0.6198510312068498 4 P17252,P21281,P10644 3 +Abnormal circulating carbohydrate concentration 0.3506325923766884 0.9468025814525988 0.3437393861218172 1.0 0.620235656518279 41 O43676,Q96RR1,P03886,Q70HW3,Q96CU9,O96000,O95831 7 +Central hypothyroidism 0.5304819503070913 0.9463865737244584 0.3439514509108852 1.0 0.6202627677652507 10 Q12824 1 +Abnormality of the cerebrospinal fluid 0.2893500343965635 0.9434841482616114 0.345433319639056 1.0 0.6212932933096016 144 Q9NPL8,P13073,Q16625,Q15392,P03886,P00846,Q02218,Q96J42,O43676,Q9BXW9,O60566,Q9NVR5,O95831,Q8N3U4,O43819,Q96CU9,Q15427,O96000,Q9P0J0,Q12824 20 +Abnormal femoral neck morphology 0.3562587139409099 0.9434031024920038 0.3454747568694736 1.0 0.6212932933096016 37 Q96AY3,Q99575,Q96DX4,Q9NUQ7,Q9Y619,Q96HY6,Q9Y487,O95831,Q9NR45 9 +Decreased lacrimation 0.6008444300097362 0.9433026607855386 0.3455261152867019 1.0 0.6212932933096016 6 Q10567,Q03001,O95163,Q7Z392,P55011 5 +Severe short stature 0.3951626042664332 0.9429874042777392 0.3456873456207154 1.0 0.6212932933096016 23 Q15392,P52732,Q96HY6,Q8IY17,P53701 5 +Focal segmental glomerulosclerosis 0.4036180827009809 0.942870332846874 0.3457472311856751 1.0 0.6212932933096016 21 P03886 1 +Aplasia hypoplasia involving bones of the thorax 0.3621881968917602 0.9426379616008436 0.3458661156635174 1.0 0.6212932933096016 35 Q14739,Q03164,O60566,Q15427,Q96HY6 5 +Cogwheel rigidity 0.600537134119855 0.9420467342263924 0.3461687135349744 1.0 0.6212932933096016 6 P00846 1 +Progressive gait ataxia 0.4746678894670905 0.9395411443660284 0.34745297803275 1.0 0.623292950945228 13 P00846,Q05086 2 +Abnormal cns myelination 0.2884302852439669 0.9393363989300204 0.347558056089988 1.0 0.623292950945228 137 Q8TD30,Q99720,O43676,P49419,Q9UBB6,P03886,O43819,Q96CU9,Q6P2C8,Q5BJH7,O96000,O95831,Q9P0J0 13 +Alacrima 0.6006493506493569 0.9364509116219591 0.3490410754948414 1.0 0.6252099928792533 5 Q03001,O95163,Q7Z392,P55011 4 +Triphalangeal thumb 0.3940306904908811 0.9350657671239064 0.349754407206853 1.0 0.6252861524645137 23 Q9BXW9,Q9NVI1,P38398,P08708,P62244,Q15427,P46783,P21281 8 +Red eye 0.4193636444475515 0.932663632887654 0.3509936674022365 1.0 0.626505965295888 17 Q14739,P06132,Q9NSE4,P28070 4 +Gynecomastia 0.4053367830895433 0.9292488877092216 0.3527601170354231 1.0 0.6286401770930239 20 Q8IY17,P31751,P51809 3 +Neuropathic arthropathy 0.532047268475671 0.924264376613281 0.3553486852170016 1.0 0.6314624912832335 3 O15269 1 +Abnormality of upper limb joint 0.3033978431793411 0.9239583305520408 0.3555080113683244 1.0 0.6314624912832335 111 Q96AY3,Q15392,Q99575,Q96DX4,P07196,Q03164,Q9UP83,Q9H1A4,Q9NUQ7,Q8WXH0,Q71SY5,Q15427,Q96J02,Q7LGA3,Q9H6K4,O95831,Q9NR45 17 +Bicornuate uterus 0.5470634583220929 0.9238196953682308 0.3555801990270195 1.0 0.6314624912832335 9 Q9BXW9,Q9NVI1,Q15427 3 +Wide intermamillary distance 0.4007911157912709 0.9237847166907376 0.3555984139654589 1.0 0.6314624912832335 21 Q9UM00,Q15555,Q9BZK7,Q9Y5P4 4 +Abnormal circulating metabolite concentration 0.2505511730519949 0.9233548515244224 0.3558223117583456 1.0 0.6316124891321732 336 Q9NPL8,P11310,Q15392,P61619,O43772,Q96RR1,Q6NUQ1,P03886,Q70HW3,Q9Y487,P06132,P00846,P41440,O43676,O75381,Q9H9P8,P48735,O96011,O14653,Q96RL7,Q9NWM8,Q9HC07,P08574,Q8NFF5,Q86U42,O75845,Q9P2R7,Q14746,Q8WXH0,Q13586,Q13423,Q9BQP7,Q9BUK6,O95831,Q86VD7,P83436,Q14739,P07196,P50416,O43819,Q96CU9,P34949,O96000,P28070,Q9P0J0 45 +Dysdiadochokinesis 0.4525022192062687 0.9215276850659262 0.3567749939274842 1.0 0.6318044256750647 14 Q6DKK2,P18887,P41440,Q9BUK6 4 +Aplasia hypoplasia of the tongue 0.5965832073256119 0.9200138709901364 0.3575655106755795 1.0 0.6322294158315283 5 Q96J42,P48651 2 +Recurrent bronchitis 0.5970654505732098 0.9171581880658792 0.3590597532882227 1.0 0.6337221992207951 4 Q03518 1 +Pseudobulbar paralysis 0.5809139038142674 0.9167967790999162 0.3592491407503315 1.0 0.6337221992207951 7 P42356,O94979 2 +Toxemia of pregnancy 0.5942045518491965 0.9162204220566628 0.3595512963070066 1.0 0.6340083192957339 6 O43772 1 +Scrotal hypoplasia 0.4032675433252253 0.9155332815469788 0.359911738733051 1.0 0.6343969558212923 20 Q15555,Q9NP72,Q8IY17 3 +Abnormality of facial skeleton 0.2466413381826487 0.9119802545424712 0.3617791119797289 1.0 0.6374404423446799 320 Q16625,Q15392,Q5JRA6,Q15555,Q13432,Q9Y619,Q9Y487,O60762,Q9NP72,Q96J42,O75381,Q9BXW9,O96011,Q9UM00,Q96RL7,Q9BZK7,Q96AA3,P46783,Q9HC07,P51812,P57678,P61586,Q9H9B1,Q05086,O75845,Q68CP9,Q96DX4,P51571,Q13724,O75648,O60566,Q6P2C8,O15160,Q9NVR5,Q9BUK6,O95831,P53701,Q8N3U4,P83436,Q03518,O15228,Q96PU5,Q14739,Q71SY5,Q9UP83,O43791,P52732,Q15427,Q7LGA3,O95363,P28070,Q9NSE4 52 +Male infertility 0.5944585513173366 0.9114425273376802 0.3620622547311396 1.0 0.6375188868081548 5 Q9NVR5 1 +Gastroesophageal reflux 0.28401946296719 0.9102854075084856 0.3626720122359237 1.0 0.6376932826869907 126 Q9H7D7,Q96RR1,Q03164,Q9Y619,P00846,Q8NC96,P29372,P57678,Q9H9B1,Q8IZA0,O15269,Q68CP9,Q05639,P51571,Q96J02,Q96F07,P12235,Q8N3U4,P83436,Q96PU5,Q14739,O43791,O96028,O94979 24 +Abnormal rib cage morphology 0.3138735895288912 0.9094517149698222 0.3631117343281183 1.0 0.6376932826869907 69 Q14739,Q99575,Q03164,Q32P28,Q15427,Q96HY6,O95831 7 +Abnormal csf metabolite level 0.319467237523493 0.9094124622682452 0.3631324459618263 1.0 0.6376932826869907 62 O43676,P13073,P03886,O43819,Q96CU9,O96000,P00846,O95831,Q9P0J0 9 +Kyphoscoliosis 0.3301274188652941 0.9090375164347902 0.3633303228730955 1.0 0.6376932826869907 49 Q68CP9,Q96AY3,Q99575,Q96DX4,Q9NWM8,O95363,Q9HC07,Q9Y487,P51812,Q9NP72 10 +Decreased circulating total igm 0.578726984403751 0.9075923776184038 0.3640936229757332 1.0 0.6387854810534747 7 Q9Y2Q5,P50851,Q13724,Q15904,Q969N2 5 +Multiple lipomas 0.5931834425962744 0.9063043986668374 0.3647747579661318 1.0 0.6392397485571196 5 O95140,Q9BUK6 2 +Abnormal chorioretinal morphology 0.3852238001388064 0.9057690459336472 0.3650581080612072 1.0 0.6392397485571196 24 O75381,O96011,P52732,Q9Y619,Q8IY17,P53701,Q96J42 7 +Abnormal choroid morphology 0.3852238001388064 0.9057690459336472 0.3650581080612072 1.0 0.6392397485571196 24 O75381,O96011,P52732,Q9Y619,Q8IY17,P53701,Q96J42 7 +Poor head control 0.3154339054556002 0.9048722211038388 0.3655330851055018 1.0 0.6398241404667401 75 Q9NPL8,P13073,O43676,Q9NQT5,P03886,Q96CU9,Q9NWM8,O96000,O95363,Q96F07,Q8NC96,P57678,Q9P0J0 13 +Pleural effusion 0.5776203386721245 0.9029404053418416 0.3665575246501329 1.0 0.6413694811375443 7 Q14739,Q9NZ08 2 +Rib fusion 0.5413523573833328 0.8978134994545897 0.3692849864910674 1.0 0.6446477798861409 9 Q9UM00,O96028 2 +Abnormality of the intrinsic pathway 0.5195107250196225 0.8940614887220533 0.371288992990797 1.0 0.6472327403057139 10 Q9Y487,P38435,P34949 3 +Deep palmar crease 0.5020560057049407 0.8935255459540675 0.3715757980068663 1.0 0.6472327403057139 11 P42345,Q9BZK7,O75431,Q9Y487,P98175 5 +Abnormality of the hairline 0.3145846863541024 0.8934372967033463 0.3716230369834794 1.0 0.6472327403057139 88 Q68CP9,Q9UP83,O43791,Q9UM00,Q9BZK7,Q96N67,Q7LGA3,P46783,O15160,O96028,O95831,Q9NR45,Q9NP72,Q8N3U4,P83436,Q12824 16 +Abnormality of the optic nerve 0.2640436713385421 0.8926828813106287 0.3720270203141111 1.0 0.6474694167299162 241 Q9NPL8,Q96RR1,P03886,Q15555,Q9NP73,Q8WWI5,Q10713,O60762,Q8IY17,P00846,Q8NC96,P41440,Q96J42,O43676,O75381,Q9H9P8,O96011,P38435,P57678,P61586,Q9NZ08,Q13724,O75648,Q6P2C8,Q96F07,Q9BUK6,O95831,Q8N3U4,Q96PU5,P07196,O43791,O43819,P52732,Q96CU9,Q7LGA3,O96000,Q9H6K4,O60313,Q9P0J0,Q12824 40 +Abnormality of the glabella 0.5603174438756207 0.8912160545317205 0.3728132731344491 1.0 0.6484983461211494 8 O43791,O96028,O60762 3 +Decreased fertility 0.3831143809583935 0.8908566185988747 0.373006095951168 1.0 0.6484983461211494 24 Q9NVR5,Q8IY17,P51809 3 +Bilateral tonic clonic seizure 0.314717379143534 0.8895641437995608 0.3736999665458154 1.0 0.6484983461211494 85 P11310,P49419,P03886,P00846,Q05086 5 +Difficulty walking 0.3144647855104298 0.8894127851126062 0.3737812763183932 1.0 0.6484983461211494 77 Q8TD30,Q99720,Q96DX4,O14653,Q96F07,P00846,Q8NC96,Q12824 8 +Aplasia hypoplasia involving the metacarpal bones 0.3828109226058712 0.8887154742327628 0.3741560125764549 1.0 0.6488999758695791 24 Q9BXW9,Q14739,Q96DX4,Q9H1A4,Q32P28 5 +Soft tissue sarcoma 0.3666461742775121 0.8864158832216498 0.3753934633917244 1.0 0.6505479683108307 30 Q13126,Q15392,Q96DX4,O60566,Q12824 5 +Epicanthus inversus 0.4589685371391436 0.8845672754523777 0.3763900629331249 1.0 0.6520256157120673 2 Q7Z6Z7 1 +Enlarged cisterna magna 0.4113960145528582 0.8831268843203418 0.3771677201044865 1.0 0.6527184533263911 17 Q9NPL8,P49419 2 +Decreased corneal reflex 0.5227123826143606 0.8825777662311117 0.3774644457761771 1.0 0.6527184533263911 3 O95163 1 +Peritonitis 0.4455083245223629 0.8822731574563009 0.3776291085432248 1.0 0.6527184533263911 14 Q8NFH4,P52565,Q9Y5K6,Q8N1F7,P38398,Q9P2R3,Q8WUM0,Q14C86,Q12769 9 +Horseshoe kidney 0.3415573927935648 0.882199140592618 0.3776691266207772 1.0 0.6527184533263911 42 Q68CP9,Q9BXW9,Q9NVI1,P51571,P08708,P62244,P46783,P98175,Q12824,O75845 10 +Aplasia hypoplasia involving bones of the feet 0.3148851401805366 0.8819596499028596 0.3777986279518317 1.0 0.6527184533263911 65 P13073,Q96DX4,Q03164,O75648,Q9BZK7,Q6P2C8,Q15427,Q7LGA3,Q13555,Q9Y5P4 10 +Recurrent otitis media 0.370938732759772 0.8810964008639207 0.3782656451265211 1.0 0.6530271998563799 28 Q9H1A4,Q9NVR5,Q13432 3 +Autoimmune antibody positivity 0.5578205246939728 0.8803667545039042 0.3786606604527964 1.0 0.6534601111813974 8 P53621,P42224,Q13546,P49327,Q96J02 5 +Abnormal cranial nerve physiology 0.3116086086978605 0.8795001913361603 0.3791301294150075 1.0 0.6537721683479193 70 O75381,Q9BXW9,Q9P2R7,P48735,O96011,Q96RR1,P07196,O75874,O43819,Q9BQP7,Q13614,Q86U42,Q12824 13 +Birth length less than 3rd percentile 0.587543017745616 0.879177108776916 0.3793052541178046 1.0 0.6538252668012385 4 Q9Y619,Q15813 2 +Generalized joint laxity 0.4809365942928279 0.8763110146511879 0.3808609787226304 1.0 0.6555092072999682 12 Q9Y487 1 +Axonal loss 0.583781182764187 0.8739598356820638 0.3821401270389262 1.0 0.6564636994639119 6 P41440 1 +Abnormal endocrine physiology 0.5843019026531098 0.8706470433926607 0.3839469017324197 1.0 0.6591030211197165 5 Q13423 1 +Patellar aplasia 0.5841032407974417 0.8698522186591833 0.3843811702557531 1.0 0.6591030211197165 5 Q9H1A4,Q9Y619,Q9Y5S9 3 +Cutaneous melanoma 0.5849901086419655 0.8690393363145534 0.3848256155799308 1.0 0.6592675175189323 4 P42771,P11802 2 +Abnormality of central nervous system electrophysiology 0.2841955823422981 0.8679271189024602 0.3854342318961556 1.0 0.6594057338815983 142 P13073,Q9NZ01,P49419,P03886,Q9NP73,Q8WWI5,O60762,Q13614,Q8NC96,O75381,O96011,Q9UBB6,Q05086,Q9NUQ7,Q13724,Q96N67,Q96F07,Q71SY5,P07196,O95363,O60313,Q9NSE4 22 +Axonal degeneration 0.5822334747799985 0.8677136327451984 0.385551120869434 1.0 0.6594057338815983 6 Q6DKK2,P50570,Q9BQT8 3 +Decreased fertility in females 0.5691874816815902 0.8676252628262119 0.3855995119320869 1.0 0.6594057338815983 7 Q9NVR5 1 +Pain 0.2817474363297543 0.8661495372583858 0.3864081624255902 1.0 0.6602900700822042 167 P11310,Q92804,Q96RR1,Q70HW3,Q96HY6,P00846,P48735,Q9BZK7,O15269,Q9BRK0,Q9NZ08,Q9NUQ7,Q8WXH0,Q13586,Q13423,Q9BUK6,Q9H6K4,Q14739,O75874,P28070,Q12824 21 +Broad philtrum 0.4425347606393284 0.865679532401275 0.3866659272621766 1.0 0.6603991533245442 14 Q9UM00,Q9BZK7,Q12824 3 +Abnormal femoral head morphology 0.4002545426458413 0.8646595705771489 0.3872256658897473 1.0 0.6607813492022303 19 Q96DX4,Q9NUQ7,Q99575,Q6NUQ1,O95831 5 +Cystoid macular edema 0.5831005503971249 0.8615487645822535 0.3889358755946279 1.0 0.6628591107763975 4 P36405,P04439 2 +Abnormal size of the palpebral fissures 0.3115508951963127 0.8578442879858805 0.3909784509050129 1.0 0.6647116077883856 88 Q03164,Q15555,Q9Y619,Q9NP73,Q9NP72,Q9BXW9,P63000,P38398,Q9BZK7,Q5KU26,Q6W2J9,Q13868,Q6DKJ4,P51812,P61586,P38159,Q68CP9,Q13724,O75648,Q6P2C8,P98175,Q08J23,P83436,Q9NVI1,O43791,Q7LGA3,Q13555 27 +Spinal canal stenosis 0.5664825147968557 0.8563504784796009 0.3918039478084645 1.0 0.6649950856396943 7 Q96T58,Q9NSE4,Q15813,P10644 4 +Lower limb hyperreflexia 0.3904546082240464 0.8546407033674617 0.3927500867104552 1.0 0.6656034017203 21 P13073,Q14739,O95363,O60762,Q05086 5 +Abnormal 5th finger morphology 0.3070149161080426 0.852954829172999 0.3936843542297414 1.0 0.6666878970694313 99 O75845,P13073,Q14739,Q9BXW9,Q96DX4,Q5JRA6,Q03164,O43791,Q9UM00,O60566,Q9Y619,Q10713,Q8IY17,Q05086,Q8N3U4,Q96J42,Q12824 17 +Abnormal palate morphology 0.2449680409358471 0.8523110274351041 0.3940414871384226 1.0 0.666938155423774 272 Q16625,Q9NZ01,Q15392,Q96RR1,Q03164,Q15555,Q9Y619,Q9Y487,Q10713,O60762,Q9NP72,Q96J42,O75381,Q9BXW9,O96011,Q9UBB6,Q9UM00,Q9BZK7,Q9NWM8,P46783,P51812,P57678,O75845,Q6PGP7,Q68CP9,Q13724,O75648,O60566,Q6P2C8,O15160,Q9BUK6,O95831,Q8N3U4,O15228,Q96PU5,Q14739,Q71SY5,P07196,Q9UP83,O43791,Q15427,Q7LGA3 42 +Foot dorsiflexor weakness 0.3637226525174103 0.8516112343572865 0.3944299021734023 1.0 0.6672021870222228 29 Q99720,Q14739,P07196,O43819,O15269 5 +Abnormal serum interleukin level 0.4518326305546405 0.8487133151858356 0.3960408352406332 1.0 0.6686877908869137 2 P49327 1 +Abnormality of malar bones 0.3110326667434314 0.8487036538052419 0.3960462125716533 1.0 0.6686877908869137 66 Q14739,Q96DX4,Q9BZK7,O60566,Q8N3U4,Q15427,Q9HC07,Q9Y487,O15160,O95831,Q9H9B1,P61586 12 +Antinuclear antibody positivity 0.5796902810696336 0.8480587813437418 0.3964052353588172 1.0 0.6689755587706144 4 P49327,P53621 2 +Supranuclear gaze palsy 0.389393012811688 0.8476019641874291 0.3966596801010751 1.0 0.6689755587706144 21 Q99720,Q96RL7,Q96RR1 3 +Abnormality of vitamin b metabolism 0.4392140963035952 0.8472221348332489 0.3968713180737238 1.0 0.6690833907234718 14 P41440 1 +Overlapping toe 0.3763000438891755 0.8430422746484346 0.3992048011058628 1.0 0.6716764614356823 24 P26196,Q71SY5,Q96DX4,Q9UM00,Q15427,Q15907 6 +Hypergonadotropic hypogonadism 0.438429669198269 0.8428737549434772 0.3992990531228018 1.0 0.6716764614356823 14 Q9BXW9,Q96RR1,P51809,P48449,Q9BQP7,O15160,O14802,P49959 8 +Aplasia hypoplasia of the ulna 0.4742344290246026 0.8421526005762575 0.3997025414787383 1.0 0.6718994492920854 12 P61254,Q9BXW9,Q9Y5S9,Q9NVI1,P38398,Q15427,Q969N2 7 +Abnormal scapula morphology 0.3311230648834696 0.8420959460912301 0.3997342502442307 1.0 0.6718994492920854 45 Q14739,P07196,Q8WXH0,Q9UM00,Q15427,P46783,Q9Y487,O60313 8 +Solitary median maxillary central incisor 0.5781153143043736 0.8418416737453611 0.3998765817420446 1.0 0.6718994492920854 4 Q8N3U4 1 +Infantile muscular hypotonia 0.3077259070918911 0.8411795629938719 0.4002473478480925 1.0 0.6722730759183757 69 P17480,Q9UP83,P03886,Q13724,O43819,Q96J02,Q9Y487,O60762,P00846,Q12824,Q8N3U4,Q05086 12 +Nephropathy 0.4036683621660457 0.8355872394831413 0.4033871498842787 1.0 0.6760428372089466 17 P03886 1 +Abnormality of the clitoris 0.3909284329833707 0.834578652417323 0.40395498583445 1.0 0.6764939319149939 20 O75381,O96011,P51809,Q9Y619,P53701 5 +Cutaneous syndactyly of toes 0.5752580188276977 0.8305842999723163 0.4062085070122916 1.0 0.6787622784085876 4 Q6W2J9 1 +Muscle spasm 0.3132572510226476 0.8283775208011267 0.4074567330301595 1.0 0.6799734685038954 59 P11310,Q92804,Q96RR1,P07196,Q13586,P00846 6 +Heterotaxy 0.5580983973879596 0.8215829992122098 0.4113142683333208 1.0 0.6831359455927111 7 P24468 1 +Poor appetite 0.4523401238296742 0.8203183797917998 0.4120346312318723 1.0 0.6834394120214835 13 Q70HW3 1 +Abnormal vertebral morphology 0.3004471442967284 0.8200607638832359 0.4121814682026115 1.0 0.6834394120214835 105 Q5JRA6,Q6NUQ1,Q9Y619,Q96HY6,Q9NR45,Q96AY3,P48735,Q99575,Q9UM00,Q32P28,O75845,Q96DX4,Q9NUQ7,Q96J02,O95831,Q8N3U4,O15228,Q14739,O75874,Q15427,Q9NSE4 21 +Ptosis 0.268509725159701 0.8199712902262359 0.412232474023011 1.0 0.6834394120214835 216 Q9NPL8,Q96RR1,Q03164,P03886,Q8NC96,O43676,O75381,Q9BXW9,O96011,Q9UM00,P46783,Q86U42,O75845,Q9P2R7,Q96DX4,Q8WXH0,O75648,Q6P2C8,Q96J02,Q9BQP7,Q96F07,Q71SY5,P07196,P52732,O43819,Q96CU9,Q15427,Q7LGA3,O96000,O95363,Q9Y5P4,Q9P0J0,Q12824,Q9NSE4 34 +Preauricular skin tag 0.4126282084351769 0.8198060323619348 0.4123266916235573 1.0 0.6834394120214835 16 Q8N3U4,Q15427,Q6W2J9,O15160,O96028,Q9Y2W2 6 +Abnormal thrombosis 0.3677719637581722 0.8163108701103662 0.4143223588877474 1.0 0.685940535439993 26 P48735,Q9NZ08,O75874,Q9BZK7,Q96AA3,P34949 6 +Abnormal peripheral myelination 0.3573634488014565 0.8161028141490267 0.4144413345472981 1.0 0.685940535439993 30 P07196,Q96RL7,P03886,Q13614,P00846 5 +Decreased activity of mitochondrial complex i 0.338599779264137 0.8157711738085935 0.4146310230232921 1.0 0.6860038474417507 39 Q9NPL8,O43676,P03886,Q70HW3,Q96CU9,O96000 6 +Abnormal thoracic spine morphology 0.3675188676887378 0.8145140027803813 0.4153505537029014 1.0 0.6866090370323156 26 Q99575,Q13724,O95831,O75845,Q9NSE4 5 +Abnormality of limb epiphysis morphology 0.3642999445099936 0.8107129347384272 0.4175305435270917 1.0 0.6893898354546324 27 Q96DX4,Q9NUQ7,Q5JRA6,Q6NUQ1,Q7LGA3,P51812,O95831,O15228 8 +Toe walking 0.3756155950626729 0.8081280620557514 0.4190168646683212 1.0 0.6912404941542225 23 Q99720 1 +Hypoplasia of the corpus callosum 0.2730035649155134 0.8068804380482879 0.4197353701216202 1.0 0.6921737264837785 181 Q9NZ01,Q9H7D7,P49419,P03886,Q15555,P48449,Q5BJH7,Q9NR45,Q9NP72,Q9BXW9,P17480,Q9UBB6,Q9UM00,Q9H9B1,Q05086,Q96DX4,Q9NUQ7,P51571,Q14746,Q13724,O60566,Q96N67,O15160,O14802,O95831,Q8N3U4,P83436,Q8TD30,Q96PU5,Q96B26,Q71SY5,P49902,Q9C0E8,Q7LGA3,Q96D71 35 +Epileptic encephalopathy 0.3708816374004323 0.805452961556018 0.4205583400963721 1.0 0.69283861970328 24 Q8NC96,Q96F07,Q96RR1 3 +Neurogenic bladder 0.5002916395700628 0.8037411343787824 0.4215464925619527 1.0 0.6941496224302602 10 Q9UP83,P83436 2 +Type ii diabetes mellitus 0.3449697020560869 0.8027141607572883 0.4221399662202725 1.0 0.6944097666735063 35 P03886,Q8IY17 2 +Intellectual disability mild 0.2816895053913228 0.8001180562731706 0.4236424005866852 1.0 0.6955781350698385 122 Q9NZ01,Q5JRA6,Q10713,Q8IY17,P00846,Q6P4A7,O96011,Q9UBB6,Q12955,Q13868,P51812,Q05086,Q6PGP7,Q96DX4,Q9NUQ7,O75648,Q13217,Q6P2C8,Q9BUK6,Q71SY5,Q9UP83,P52732,Q7LGA3 23 +Functional abnormality of male internal genitalia 0.3626270899588342 0.7987130225096095 0.4244568339631454 1.0 0.6964105243944398 27 Q9H1A4,Q9NVR5,Q13423,P51809 4 +Ependymoma 0.503373234661647 0.7972851122064353 0.4252854647537707 1.0 0.6968206397936558 3 O75874 1 +Facial asymmetry 0.3530909318900708 0.7972220359895702 0.4253220902934786 1.0 0.6968206397936558 31 Q03164,Q9BXW9 2 +Large earlobe 0.5520472195706183 0.7966711322398676 0.425642053760825 1.0 0.6970927344672947 7 Q15392 1 +Thromboembolism 0.5654298555443523 0.792089393374382 0.4283085541971458 1.0 0.7003369252030934 4 Q14315,P10644 2 +Stenosis of the external auditory canal 0.5372427720891687 0.7919395190989279 0.4283959425469694 1.0 0.7003369252030934 8 P08754,O96028,P55011 3 +Abnormality of femur morphology 0.3047722326812119 0.7901717695792421 0.4294274604010186 1.0 0.701516911509778 67 Q9BXW9,Q96AY3,Q14739,Q99575,Q96DX4,Q9NUQ7,Q6NUQ1,Q9Y619,Q32P28,Q7LGA3,Q96HY6,Q9Y487,P51812,O95831,Q9NR45 15 +Subcortical heterotopia 0.56418273292252 0.7872312916580264 0.431146482505726 1.0 0.7027572600120029 4 P07942,P43034 2 +Subcortical band heterotopia 0.56418273292252 0.7872312916580264 0.431146482505726 1.0 0.7027572600120029 4 P07942,P43034 2 +Increased muscle fatiguability 0.5631985631817098 0.7869869284491745 0.4312895181629219 1.0 0.7027572600120029 5 Q13586 1 +Bronchitis 0.5620181823285606 0.7869210247615305 0.4313280989637462 1.0 0.7027572600120029 6 Q03518 1 +Cerebellar cyst 0.3403262153217268 0.786802960696723 0.4313972200713389 1.0 0.7027572600120029 36 Q68CP9,Q9NQT5,O60566,Q9Y487,Q96J42,Q12824 6 +Optic disc hypoplasia 0.500882158039839 0.7864208502424289 0.4316209722768862 1.0 0.7027572600120029 3 O14802 1 +Broad based gait 0.368080292451067 0.7861832221436859 0.4317601539445759 1.0 0.7027572600120029 24 Q03164,Q05086 2 +Sclerocornea 0.496484206961881 0.7860873656749608 0.4318163056050164 1.0 0.7027572600120029 10 P53701,Q96J42 2 +Enlarged thorax 0.4456845050398475 0.7854266312744055 0.4322034716100309 1.0 0.7027572600120029 13 Q99575,Q32P28 2 +Erythema 0.4175093871168711 0.7848596902635799 0.4325358383546613 1.0 0.7027931663366629 15 Q9H1A4,P53701,P03886 3 +Clinodactyly 0.2773093662171327 0.7824415092053721 0.4339551472373666 1.0 0.7033333871145869 135 Q5JRA6,Q03164,Q9Y619,Q9NP73,Q10713,Q8IY17,Q9NP72,Q9BXW9,P51812,P61586,Q05086,Q96DX4,P51571,O75648,O60566,Q6P2C8,Q96J02,Q8N3U4,Q71SY5,Q9UP83,O43791,Q15427,Q7LGA3,Q12824 24 +Widely spaced teeth 0.3445982569848136 0.780355076322703 0.435181902620203 1.0 0.7043575378159045 34 P51571,Q9BZK7,Q6P2C8,P51812,Q9Y5P4,Q05086 6 +Abnormality of the thyroid gland 0.2972102220560597 0.7803090363020216 0.4352089952200257 1.0 0.7043575378159045 105 Q96RR1,P03886,P48735,Q9H1A4,Q13868,Q6PGP7,Q68CP9,Q13724,O60566,Q96J02,Q13423,O15160,Q14145,Q9BUK6,Q8N3U4,O75874,O43791,P34949,O60313,Q12824 20 +Subcutaneous hemorrhage 0.3342721279112748 0.7796311278275412 0.4356080282761287 1.0 0.7044827751733005 39 Q9BXW9,Q16625,P38435,Q9BZK7,Q13586,Q9NWM8 6 +Neoplasm of the skeletal system 0.3363831063841407 0.7776757973320045 0.4367601638117688 1.0 0.7056075399669447 37 Q13126,P48735,Q92804,Q9H1A4,O75874 5 +Non midline cleft lip 0.5606829468152349 0.7771291152907059 0.437082597890714 1.0 0.7056251491250658 5 O43791 1 +Bifid tongue 0.4986704759362661 0.7768012259210756 0.4372760533828459 1.0 0.7056859714372254 3 Q6DKJ4 1 +Abnormality of skeletal muscle fiber size 0.3901940091533343 0.7755896729621463 0.4379912998467061 1.0 0.7060887902029342 18 O95831,Q9BUK6,Q13586,Q96RR1 4 +Abnormal pleura morphology 0.4260830895128343 0.7750792823103234 0.4382928128920558 1.0 0.7063203281398125 14 Q14739,Q9NZ08,Q14145 3 +Abnormal intraocular pressure 0.5594155844155869 0.7721730093520796 0.4400119651382992 1.0 0.7079868769881021 5 Q8NCH0,Q12797,P04439,Q99496 4 +Elevated hepatic transaminase 0.2996130694598485 0.7706931897506921 0.440888809548511 1.0 0.7089905244070838 100 Q14739,P11310,Q16625,O43772,Q9UP83,P50416,Q96RR1,Q96RL7,Q14746,Q6NUQ1,O75648,Q9Y619,Q9HC07,Q10713,P08574,P28070,P83436,O75845 18 +Abnormal peripheral nervous system physiology 0.3188384473230263 0.7664845926165346 0.4433880160281767 1.0 0.7113057898440983 47 Q9P2R7,Q99720,Q71SY5,P07196,Q96RL7,Q13724,Q13614,O95831,O60313,O15269 10 +Abnormal lumbar spine morphology 0.4922190816556245 0.7664178496376001 0.4434277153465196 1.0 0.7113057898440983 10 Q99575,O75845 2 +Abnormal thalamic mri signal intensity 0.5445019569162164 0.7658418964045081 0.443770381827455 1.0 0.7116034795321668 7 Q12824 1 +Hypoplastic vertebral bodies 0.5565852457402166 0.765489065241734 0.4439803753071234 1.0 0.7116882873819069 6 Q6NUQ1,Q14739 2 +Tongue fasciculations 0.475392506251602 0.7640152078446945 0.4448581799066822 1.0 0.712087475256986 11 O95831,Q9NQT5,Q9BQT8 3 +Limb pain 0.5107860069892738 0.7611094151138452 0.4465917173725016 1.0 0.7138903265947864 9 P00846 1 +Abnormality of finger 0.2435849090763474 0.7610707145697685 0.4466148312515727 1.0 0.7138903265947864 267 P13073,Q5JRA6,Q03164,Q15555,Q9Y619,Q9NP73,Q10713,Q8IY17,Q9NP72,Q96J42,Q9BXW9,Q9H1A4,Q9UM00,Q9BZK7,P38435,Q96AA3,Q13868,P46783,P51812,Q9H9B1,Q05086,O75845,Q96DX4,Q13724,O75648,O60566,Q6P2C8,O95831,Q8N3U4,Q9H6K4,P83436,Q14739,Q71SY5,Q9UP83,O43791,Q15427,Q7LGA3,P28070,Q12824,Q9NSE4 40 +Soft skin 0.5106696398807956 0.7605984227444301 0.4468969621357535 1.0 0.7140893257407278 9 Q9NWM8 1 +Hepatic failure 0.3196462814599712 0.7582398984598493 0.448307379888164 1.0 0.7147473547745221 46 O75381,O96011,O43772,Q6NUQ1,P50416,P03886,O75648,Q9Y619,P34949,Q96J02,P08574,P00846,O75845 13 +Urinary incontinence 0.3171235718501205 0.7510189396945997 0.4526412575231078 1.0 0.7197138984133655 47 Q99720,P07196,Q9UP83,Q8WWI5,O95363,Q12824 6 +Specific learning disability 0.3049509531339765 0.7492502214938592 0.4537064044505872 1.0 0.7209014423574746 60 Q96RR1,P52732,P03886,Q9Y619,Q13586,Q8N3U4,Q10713,Q9H6K4,P53701,Q9H9B1,O75845 11 +Brain imaging abnormality 0.3316028104635095 0.7477130931733026 0.4546332319246349 1.0 0.722120806668512 38 P03886,Q9BZK7,Q05086,O43819 4 +Abnormal abdomen morphology 0.2631423972572868 0.7468507172566204 0.4551536772211515 1.0 0.7221877960811967 221 Q9NPL8,P11310,Q16625,Q15392,O43772,Q6NUQ1,P03886,Q9NRW7,Q96HY6,P06132,P00846,O43676,O75381,O96011,P00374,Q96RL7,Q96AA3,Q9HC07,P09601,O75845,Q9NZ08,Q14746,Q13724,O75648,O60566,P83436,Q14739,Q9UP83,P50416,Q96CU9,P34949,O96000,P28070 33 +Abnormality of krebs cycle metabolism 0.552817477369614 0.74648612932808 0.4553738074962545 1.0 0.7222840854194793 5 P03886 1 +Abnormality of temperature regulation 0.3002184528959994 0.7459280801443113 0.4557108615186931 1.0 0.7225656992228491 94 O43772,P03886,Q9BZK7,Q13586,Q9HC07,P28070,P00846,Q8N3U4,Q05086 9 +Neoplasm by histology 0.2996856462301882 0.7440656316290827 0.4568367702305291 1.0 0.7231239326280003 95 Q13126,Q15392,P48735,Q92804,Q96DX4,Q9H1A4,O75874,Q15555,P51809,O60566,P46783,P11802,Q12824 13 +Atonic seizure 0.3732255187340441 0.7421188166138808 0.4580153501569588 1.0 0.7246977073737421 21 O14653,P49419 2 +Frontotemporal dementia 0.5382597166448899 0.7405490069015009 0.4589669363845585 1.0 0.7256964125033334 7 P35637,O96008 2 +Multiple prenatal fractures 0.5379849806631025 0.7394404723383813 0.4596395740015748 1.0 0.7263330830018973 7 Q32P28 1 +Profound global developmental delay 0.4193498826316516 0.7386773394148057 0.4601029490801493 1.0 0.7263330830018973 14 P83436,O75381,O95363,O96011 4 +Upper limb muscle weakness 0.358997311210914 0.7385648234415836 0.460171290996787 1.0 0.7263330830018973 25 P50402,P50570,P07196,Q02809,Q8WXH0,Q8N0X7,O95140,P36551,P00846,Q12824 10 +Psychomotor deterioration 0.5052932869467324 0.7370806337983868 0.4610733154444881 1.0 0.7268102401039788 9 Q03164 1 +Abnormality of the musculature of the limbs 0.2753626611214486 0.7367829892226583 0.4612543294621725 1.0 0.7268102401039788 153 Q99720,Q14739,Q13126,Q96RR1,P07196,Q9BQT8,O43819,Q96RL7,Q13586,P46783,Q9Y487,Q96F07,Q8IY17,P00846,Q8NC96,Q86U42,Q12824,O15269 18 +Neck muscle weakness 0.4185632807337474 0.734453673852913 0.4626722845723137 1.0 0.7284120102018875 14 Q99720 1 +Infectious encephalitis 0.5045931704393645 0.7340315454421836 0.4629295123784833 1.0 0.7284120102018875 9 Q14739,Q9H9P8 2 +Aplasia hypoplasia of the phalanges of the hand 0.3052616006670967 0.7340215896501783 0.4629355799936498 1.0 0.7284120102018875 53 Q9BXW9,Q14739,Q5JRA6,Q03164,Q9H1A4,P38435,Q9NP73,P51812,Q12824 9 +Impaired social interactions 0.3073451820914937 0.7328283501340909 0.4636631277901493 1.0 0.7293034614199223 51 O43676,Q96RR1,P03886,Q96CU9,Q96N67,O96000,Q9P0J0 7 +Recurrent tonsillitis 0.4281543950697329 0.7318316375136962 0.4642713361390072 1.0 0.7295002263994934 2 Q13546 1 +Oligospermia 0.4281543950697302 0.7318316375136826 0.4642713361390154 1.0 0.7295002263994934 2 P16435 1 +Spotty hyperpigmentation 0.4281543950697302 0.7318316375136826 0.4642713361390154 1.0 0.7295002263994934 2 O75531 1 +Abnormal tricuspid valve morphology 0.4680631069360968 0.7292314450769143 0.4658600992660895 1.0 0.7304988578018564 11 P53701,P51812,P24468 3 +Macular thickening 0.5470667585203792 0.7282705986916116 0.4664479565187025 1.0 0.7304988578018564 6 P36405,P04439 2 +Abnormal morphology of the radius 0.4072804977624874 0.7277970102010004 0.4667378550049017 1.0 0.7304988578018564 15 Q32P28,Q15427,P98175 3 +Sleep wake cycle disturbance 0.5464276527751232 0.7257875983404765 0.467968990750518 1.0 0.7312926147835782 6 Q05086 1 +Athetosis 0.4067519731891523 0.7248787654806427 0.4685264089266856 1.0 0.7318705629096157 15 Q9P2R7,Q96RR1 2 +Recurrent bacterial infections 0.381604927409703 0.7234083313296923 0.4694290541974677 1.0 0.7327751948706164 18 Q9NVR5,Q13586 2 +Abnormal metacarpal morphology 0.3481663730542465 0.7159491653182416 0.4740227385471449 1.0 0.7373075224255694 28 Q9H1A4,Q14739,Q96DX4,Q32P28 4 +Slowly progressive 0.3019851200528423 0.7155876742922477 0.4742459866331145 1.0 0.7373075224255694 59 Q99720,P07196,Q13586,O95831,P41440,Q9P0J0,Q9BRK0 7 +Increased circulating androgen concentration 0.4844354182035097 0.7155263543133455 0.4742838620941709 1.0 0.7373075224255694 3 O14802 1 +Abnormality of facial musculature 0.2988846441123492 0.7152705904981197 0.4744418574407743 1.0 0.7373075224255694 78 Q96RR1,Q9NP73,Q13614,O75381,O96011,P50570,P51812,Q9H553,Q86U42,Q15907,Q9P2R7,Q9BQT8,Q14315,Q9BQP7,Q9BUK6,Q86VD7,Q8N3U4,P07196,O43819,Q13555,O60313,Q12824 22 +Abnormal activity of mitochondrial respiratory chain 0.3010491361436773 0.7144026249844151 0.4749782492745917 1.0 0.7373075224255694 61 O43676,P13073,Q9P2R7,P03886,Q70HW3,Q96CU9,O96000,Q9P0J0 8 +Color vision defect 0.4147851098540756 0.7142559474158573 0.4750689270460015 1.0 0.7373075224255694 14 Q13432,Q9H6K4 2 +Cerebral palsy 0.4645979105785252 0.712931071928352 0.4758884107602925 1.0 0.7382789386110018 11 O75874,P48735,Q12824,P61457 4 +Dementia 0.3027249216732051 0.7119252636249973 0.4765110569593287 1.0 0.7388586854395464 55 Q96RR1,P03886,Q9Y487,Q8IY17,P00846 5 +Large for gestational age 0.4994659286655261 0.711800508757989 0.4765883176278929 1.0 0.7388586854395464 9 P42345,P31751,Q9UM00,Q12955,Q9H9B1 5 +Abnormal forearm bone morphology 0.3646419781025019 0.7096679727831471 0.4779100573539554 1.0 0.7398949281658982 22 Q9BXW9,Q9NVI1,Q15427,Q32P28,P98175 5 +Finger syndactyly 0.3352807304186944 0.7087269476490751 0.4784939388003175 1.0 0.7403258884141576 34 Q9BXW9,Q71SY5,P98175,P48651,Q9NVI1,P38398,Q9Y619,Q15427,Q6DKJ4,Q8IY17,Q05086 11 +Abnormally lax or hyperextensible skin 0.3213984475245228 0.708692570624928 0.4785152762200118 1.0 0.7403258884141576 42 Q15555,P38435,Q9BZK7,Q9NWM8,Q9Y487 5 +Abnormal glial cell morphology 0.3025513911119791 0.7083764234245524 0.4787115294877937 1.0 0.7403766570774003 53 Q9H9P8,P48735,O95831,O75874,O43819,O95363,Q10713,P00846,Q9H9B1 9 +Cutaneous syndactyly 0.4980709277587986 0.7057828974682558 0.4803231593554324 1.0 0.7423623036097267 9 P27635,Q9Y619,Q6W2J9,P98175,P21281 5 +Gastrointestinal atresia 0.4300188733769113 0.7047715661809865 0.4809524061167916 1.0 0.7429481967874711 13 Q9BXW9,Q8N3U4 2 +Abnormal globus pallidus morphology 0.497807133152776 0.7046464947019004 0.4810302563306077 1.0 0.7429481967874711 9 O43819 1 +Congenital hip dislocation 0.3538270706996094 0.7035106845784369 0.481737550549504 1.0 0.7437870156745922 25 Q9Y487,Q9NSE4 2 +Myoclonic seizure 0.3019174373754336 0.7024201871712386 0.4824171595464404 1.0 0.7443289280467897 53 P00846,P03886,P49419,Q9C0E8 4 +Hemiparesis 0.3778323003011745 0.7007990768373836 0.4834284142692373 1.0 0.744955453656375 18 Q9NZ08,O43791,P03886,O60313,Q12824 5 +Minimal change glomerulonephritis 0.4288127670691621 0.6986575175242816 0.4847660891183671 1.0 0.7454889237327432 13 Q8NFH4,P52565,Q9Y5K6,Q8N1F7,Q9P2R3,Q8WUM0,Q14C86,Q12769 8 +Short nose 0.292691784063961 0.6964766520581117 0.486130374044273 1.0 0.746060166564857 101 O75845,Q15392,Q96DX4,Q03164,O43791,Q9UM00,Q9BZK7,P38435,Q9Y487,P83436,Q12824 11 +Proximal tubulopathy 0.3527367939707316 0.6961834034183625 0.4863139799677718 1.0 0.746060166564857 25 O43676,O96000,P03886,Q96CU9 4 +Abnormal pancreas morphology 0.3907827858434717 0.6938680314049438 0.487764973518991 1.0 0.7472354853030199 16 Q9NQH7,Q96J42 2 +Infantile spasms 0.3371912392226353 0.6926135429635512 0.4885521089909925 1.0 0.7477899613247035 32 P03886 1 +Abnormal cerebral cortex morphology 0.2616402858531926 0.6924019974851578 0.488684911767427 1.0 0.7477899613247035 213 Q16625,Q9NZ01,Q15392,Q96RR1,O96008,P03886,Q9Y619,Q9Y487,Q10713,O60762,P00846,Q9NP72,O75381,P17480,O96011,Q9UBB6,Q9UM00,Q96RL7,Q9BZK7,Q96AA3,P51812,Q9H9B1,Q05086,Q9NUQ7,O75648,Q6P2C8,Q96N67,Q96PU5,Q96B26,Q71SY5,O43791,O43819,P52732,Q15427,Q7LGA3,Q12824,Q9NSE4 37 +Tetraplegia 0.4440815274772 0.692366720744333 0.4887070594849225 1.0 0.7477899613247035 12 Q13423 1 +Abnormal nephron morphology 0.300618823642223 0.6902711120190552 0.4900237108937058 1.0 0.7489228779853196 53 P00846,Q9NQH7,P03886,O43819 4 +Pes cavus 0.2934946862984511 0.6881375035920487 0.4913661952603416 1.0 0.7507213708362049 98 Q99720,Q9H7D7,Q9UHD1,Q96RR1,Q10713,P50570,Q96RL7,O00400,Q15907,O15269,Q9BRK0,Q96DX4,O75648,Q8TB36,Q6P2C8,Q9BUK6,O95831,Q14739,Q71SY5,P07196,P49959,Q7LGA3,Q96D71,Q9H6K4,Q99653,O60313 26 +Oromotor apraxia 0.5373905521796523 0.6872545584571543 0.4919223289856502 1.0 0.7510923772746023 5 Q8N3U4,P42356 2 +Prominent digit pad 0.3645370805635772 0.6869763572495636 0.4920976273462039 1.0 0.7510923772746023 21 P26196,O75648,Q9BZK7,Q6P2C8,Q6W2J9,Q7LGA3,P55011 7 +Narrow mouth 0.2930517343613749 0.6844231915462495 0.493707975587635 1.0 0.7522694683525013 69 Q15392,Q15555,O75648,Q9Y619,Q6P2C8,Q7LGA3,O15160,Q9Y487,Q9NSE4,P83436,Q6PGP7 11 +Heinz bodies 0.417774894583193 0.6818485657454971 0.4953347113207309 1.0 0.7542407537085415 2 O14936 1 +Abnormal reflex 0.242085485004301 0.6810621032817605 0.4958321950956017 1.0 0.7546139626822379 348 Q99720,P11310,P13073,Q16625,Q96RR1,P03886,Q15555,Q8WWI5,Q8IY17,P00846,Q8NC96,P41440,O75381,Q96AY3,Q9BXW9,O96011,O14653,Q96RL7,Q96AA3,Q96IX5,P57678,Q05086,Q9BRK0,O15269,Q9P2R7,Q9NZ08,Q9NQT5,Q9BQT8,Q8WXH0,Q13586,Q9BQP7,Q96F07,Q9BUK6,O95831,P83436,Q8TD30,Q14739,P07196,Q9UP83,P50416,O43819,Q96CU9,O95363,Q9H6K4,Q9P0J0,Q9NSE4 46 +Ventricular hypertrophy 0.3293191297694471 0.6809344430877506 0.4959129728267157 1.0 0.7546139626822379 35 P03886,O43772 2 +Arteriovenous malformation 0.5346954946947808 0.6805941278193722 0.4961283436036088 1.0 0.7546881788194586 6 Q9BXW9,P38398,Q9NVI1 3 +Interictal eeg abnormality 0.2960444254630283 0.6801821598256896 0.4963891270332874 1.0 0.7548314016316858 82 P13073,Q9NZ01,P49419,Q9UBB6,Q9NUQ7,Q71SY5,Q96N67,Q96F07,Q8NC96,Q05086,Q9NSE4 11 +Hypoplastic fifth fingernail 0.5101178970729418 0.6787253782005815 0.4973118829950791 1.0 0.7555828226316585 8 Q12824 1 +Autism 0.310522391088777 0.6782291049570579 0.4976264413563602 1.0 0.7556982163407012 46 Q8NC96,Q05086 2 +Prominent eyelashes 0.4911849938563219 0.6762832560938736 0.498860821468154 1.0 0.7568116280143128 9 Q12824 1 +Hypoplastic fifth toenail 0.4911849938563219 0.6762832560938736 0.498860821468154 1.0 0.7568116280143128 9 Q12824 1 +Abnormal circulating lipid concentration 0.2945441817158157 0.6738638477422021 0.5003978782264609 1.0 0.7588893164934274 76 O75381,P11310,Q14739,Q15392,O96011,O43772,Q8WXH0,P50416,P28070,O75845 10 +Abnormality of the cervical spine 0.2916491626358393 0.6727222452900996 0.5011240125878889 1.0 0.7589741815523693 99 Q99575,Q96DX4,Q9UP83,Q9UM00,Q15555,Q9BZK7,Q96AA3,Q15427,O60566,P46783,Q96HY6,O95831,Q9NR45,P83436 14 +Hypoplastic fingernail 0.3859806460324865 0.666955162764268 0.5048007738144111 1.0 0.763350873303559 16 Q68CP9,Q14739,P48651,P51812,Q12824 5 +Abnormality of the skull base 0.297474525097731 0.6660336252265499 0.505389608073789 1.0 0.763350873303559 57 Q9NPL8,Q68CP9,Q14739,P49419,O60566,Q96AA3,Q9Y487,Q10713,O14802,Q96J42,Q12824 11 +Abnormality of the tongue 0.2944544023147677 0.665852133188905 0.5055056185466626 1.0 0.763350873303559 88 O75381,Q9NQT5,Q99575,P07196,O96011,Q9BQT8,Q96RL7,O75648,Q71SY5,Q7LGA3,O15160,Q10713,O95831,Q05086,Q9H9B1,Q96J42,P83436,Q12824 18 +Abnormality of the calf 0.2973456755248716 0.6648189623319792 0.5061662927152404 1.0 0.7638019007328577 57 Q13126,Q96DX4,Q9NUQ7,Q9H1A4,Q9UP83,Q32P28,Q15427,Q7LGA3,Q96HY6,O95831,Q9NR45,Q9NSE4 12 +Abnormal platelet volume 0.50662809277067 0.6644971349712443 0.5063721820344702 1.0 0.7638581367353148 8 Q14739,O75845 2 +Bradycardia 0.4540423480220788 0.6639041312135895 0.5067516719920824 1.0 0.7641761232104305 11 O43772 1 +Abnormal motor nerve conduction velocity 0.3678149412270504 0.66299525365052 0.5073335939069898 1.0 0.7644348178285874 19 Q99720,Q13614 2 +Aplasia hypoplasia of the 5th finger 0.3946964540911697 0.6592141279014618 0.5097582759231378 1.0 0.7671777375188753 15 Q12824 1 +Narrow forehead 0.3101379074961785 0.6581861874364942 0.5104184992847529 1.0 0.7679162410361776 45 Q8TD30,Q9UM00,O43791,Q96N67,Q7LGA3,P83436,O75845 7 +Central primitive neuroectodermal tumor 0.4707080748547936 0.657629747661168 0.5107760746449157 1.0 0.7679303603817561 3 Q14145 1 +Accessory spleen 0.5035097980728755 0.6518571026281373 0.5144933603934174 1.0 0.7712292927141564 8 Q96J42 1 +Abnormal male reproductive system physiology 0.3201803647568756 0.6494501292729508 0.5160474711684349 1.0 0.7727917502125653 37 P51809,Q9H1A4,Q13423,Q9NVR5,Q12824 5 +Clonus 0.3327296148771742 0.6481076899192719 0.5169153006263483 1.0 0.7732516046148309 31 Q99720,Q9BQT8,Q9Y619,Q8WWI5,Q9NP72 5 +Developmental regression 0.2766722110840362 0.6476293051475107 0.5172247384618343 1.0 0.7732765891855146 116 P13073,O75381,Q9H9P8,O96011,P03886,O43819,Q6P2C8,O95363,Q96F07,P00846,Q8NC96,Q86VD7,O95831,Q96IX5 14 +Lower eyelid coloboma 0.5273196574779297 0.6469100285338452 0.5176901749398595 1.0 0.7734890230427794 4 Q15427 1 +Abnormality of thalamus morphology 0.3923937760496063 0.6468819846448413 0.5177083262396704 1.0 0.7734890230427794 15 O43819,Q12824 2 +Breast carcinoma 0.3546081961929935 0.6459538015130579 0.5183092749761227 1.0 0.7739412728182352 22 P42771,P48735,O75874,P38398,P49959,P43246,Q92878 7 +Abnormality of tibia morphology 0.4490871673205775 0.6412405428481567 0.5213664123361275 1.0 0.7771602000271988 11 Q32P28 1 +Gangrene 0.4478650937515446 0.6356879760387243 0.5249798149839167 1.0 0.7810044538184376 11 Q9NZ08,Q9BZK7 2 +Papillary thyroid carcinoma 0.4628889416883354 0.6347406552721779 0.5255975735838243 1.0 0.7814100461749709 10 Q12824 1 +Abnormality of somatosensory evoked potentials 0.4648635318179561 0.6333859964222249 0.5264816074582619 1.0 0.7822111124256893 3 Q9Y6X9 1 +Delayed gross motor development 0.2815316364780122 0.6304958365722906 0.5283702259203149 1.0 0.7845024986624144 109 Q99720,Q9P2R7,Q9UBB6,Q03164,Q6P2C8,Q5BJH7,Q86VD7,Q8N3U4,Q05086 9 +Abnormal nipple morphology 0.2930501013627102 0.6300233850738327 0.5286792842864194 1.0 0.7847041801498952 59 Q9UM00,Q15555,Q9BZK7,Q96AA3,Q7LGA3,O60762,Q8IY17,P83436,Q9Y5P4 9 +Infertility 0.4798842965335721 0.6286630991972144 0.5295696411054325 1.0 0.7857682522789418 9 Q9NVR5 1 +Paroxysmal involuntary eye movements 0.3512825194642848 0.6252587387805252 0.5318012558915333 1.0 0.7872119207781455 22 O43676,O96000,P03886,Q96CU9 4 +Prominent nasal bridge 0.3041593241730673 0.6242277816743709 0.5324780041998589 1.0 0.7877613843975705 46 P13073,Q5JRA6,Q15436,Q9Y5N6,Q10713,Q96T58,Q92766,P63000,P78318,P38398,Q6W2J9,P36405,Q96N67,Q08J23,P49366,Q5T160,O43791,Q15427,P46109 19 +Decreased activity of mitochondrial complex iv 0.3642594913852593 0.6212474880003654 0.5344367986035861 1.0 0.7892650667880243 18 Q70HW3 1 +Abnormal glomerular mesangium morphology 0.3875309537210741 0.6210801847402223 0.5345468661774948 1.0 0.7892650667880243 15 Q8NFH4,P52565,Q9Y5K6,Q8N1F7,P53621,Q9P2R3,Q8WUM0,Q14C86,Q12769 9 +Joint laxity 0.2896080643341998 0.6206526902505924 0.5348281635780459 1.0 0.7892650667880243 77 Q96AY3,Q9BZK7,Q32P28,Q9HC07,Q96HY6,Q9Y487,Q9NR45,Q12824 8 +Micropenis 0.2919816622964257 0.6200531074088673 0.535222823299208 1.0 0.7892650667880243 59 Q9BXW9,P51809,Q9UP83,Q9Y619,Q9BZK7,O60566,Q10713,Q8IY17,P53701,Q9NP72 10 +Increased bone mineral density 0.3566773967985512 0.6200320179687357 0.5352367075436668 1.0 0.7892650667880243 20 Q14739,Q15392 2 +Xerostomia 0.4128191991781777 0.6190778954484781 0.5358650444784436 1.0 0.7894810708749846 13 Q14739,Q92804,Q15165,P35637,P55011 5 +Atrophy degeneration affecting the cerebrum 0.2473789547757217 0.6176575078410692 0.536801127681358 1.0 0.7902857030863022 245 P13073,Q16625,Q9NZ01,Q96RR1,O96008,P03886,Q9Y619,Q5BJH7,Q9NP73,Q10713,O60762,P00846,Q9NR45,Q8NC96,Q9NP72,Q9H9P8,P17480,Q9UBB6,P00374,Q9UM00,Q96RL7,Q96AA3,P51812,O00400,Q9H9B1,Q05086,O75845,Q9P2R7,Q9NQT5,Q9NUQ7,Q14746,Q13724,O75648,Q13217,Q6P2C8,Q96N67,Q96F07,O95831,P83436,Q96B26,Q71SY5,Q9UP83,Q7LGA3,O95363,Q96D71,O60313,Q9NSE4 47 +Hypogonadism 0.2898368356305655 0.6163031683384097 0.5376944481587782 1.0 0.7913436810134065 81 Q9BXW9,Q9Y2R9,Q96RR1,Q9H1A4,P51809,P03886,Q15555,P48449,Q9BQP7,O15160,O60313,O14802,Q8IY17,P49959,Q9BT22,Q16740,Q12824 17 +Decreased circulating iga level 0.4943863811396023 0.615296388072004 0.5383590024654801 1.0 0.792064397911213 8 P42345,P50851,Q13724,Q96J02,Q969N2 5 +Abnormal corneal epithelium morphology 0.411809297917003 0.614153677421979 0.5391137804628017 1.0 0.7929173459404193 13 Q14739,P06132,Q9NSE4 3 +Choreoathetosis 0.3258364860597207 0.6111415006556011 0.5411059073840441 1.0 0.7937855441870855 32 P00846,Q96RL7,Q9P0J0,Q86VD7 4 +Abnormal tongue morphology 0.2864013875174565 0.6093984784973249 0.5422603461592894 1.0 0.7951713257262708 68 Q99575,Q9NQT5,Q71SY5,P07196,Q96RL7,O75648,Q7LGA3,Q10713,Q12824,Q9H9B1,Q96J42,P83436,Q05086 13 +Calcinosis 0.5164553469170026 0.6090364863012141 0.5425002548336386 1.0 0.7951713257262708 5 Q9H1A4,P57678 2 +Abnormal cardiac ventricular function 0.3586557970411929 0.6088855166616949 0.5426003249045688 1.0 0.7951713257262708 19 P03886 1 +Abnormal pattern of respiration 0.2618842141041304 0.6086556615447846 0.5427527017981522 1.0 0.7951713257262708 176 P11310,P49419,Q92804,O43772,Q96RR1,P03886,Q9Y619,Q15165,Q10713,P00846,Q9BZK7,P51571,Q13724,O75648,O60566,Q6P2C8,Q9BQP7,O95831,P53701,Q8N3U4,O43791,O43819,Q96CU9,O95363,O60313,Q9P0J0 26 +Chronic lung disease 0.4563896245466092 0.6065558006489026 0.5441457402133161 1.0 0.7966968982438015 10 Q8N3U4,Q96J02 2 +Abnormal auditory evoked potentials 0.5040285587693067 0.605959313730904 0.5445417709535851 1.0 0.79701913486906 7 Q13724,Q13614,P07196 3 +Abnormal labia minora morphology 0.4917402722158842 0.6048160283450421 0.54530124246432 1.0 0.7976153142923376 8 Q9Y619 1 +Brushfield spots 0.515416797337129 0.6032230515487358 0.546360314665215 1.0 0.7983910404623947 4 O75381 1 +Subsarcolemmal accumulations of abnormally shaped mitochondria 0.5143172259606862 0.5992342931230391 0.5490166574313862 1.0 0.8014970860986721 4 Q96RR1 1 +Abnormality of the peritoneum 0.3603429311566778 0.5988687120544021 0.5492604372289982 1.0 0.8015946458271139 18 Q8NFH4,P42771,Q9Y5K6,P38398,O95163,Q14C86,Q12769 7 +Upgaze palsy 0.5119343217469963 0.5952879558691216 0.55165100533314 1.0 0.8037957239463641 6 Q96RR1 1 +Occipital encephalocele 0.5132250927912005 0.5952807382521909 0.5516558290837188 1.0 0.8037957239463641 4 Q10713 1 +Abnormal cartilage morphology 0.4387951756329082 0.5949610392044621 0.5518695143653392 1.0 0.8038485209244329 11 O75874,P48735,Q7LGA3 3 +Abnormal size of the clitoris 0.3621719060873761 0.5922858758167926 0.5536591723070536 1.0 0.8056781402348067 17 P53701,O75381,O96011,P51809 4 +Butterfly vertebrae 0.5119963430380323 0.5908425258096663 0.5546259383969461 1.0 0.8067897976120488 4 Q8N3U4 1 +Kinetic tremor 0.3209018291658301 0.5889607870063507 0.5558875788408879 1.0 0.80762371140129 33 P41440,Q8IY17 2 +Hemivertebrae 0.4371101893442033 0.5874928433892336 0.5568727555212922 1.0 0.8087956340209854 11 P63241,Q9UM00,Q9Y619,O60216,Q8N3U4 5 +Abnormal eyelash morphology 0.2861201714230197 0.581645613374667 0.5608054120755299 1.0 0.8121638480505596 79 O94979,Q03164,Q9Y619,P48449,P06132,Q8IY17,Q9H1A4,Q9UM00,Q68CP9,Q13724,Q6P2C8,Q96N67,O15160,O14802,P53701,Q8N3U4,O43791,P52732,Q15427,Q12824 20 +Abnormality of the tonsils 0.4848373037604052 0.577753672897316 0.5634304366581491 1.0 0.8146632231284441 8 Q96DX4 1 +Delayed ability to walk 0.2831237453394841 0.5774869470799361 0.5636105537705367 1.0 0.814663627498574 68 Q99720,Q9UBB6,O43791,O75648,Q96D71,Q86VD7,Q8N3U4,Q05086 8 +Delayed closure of the anterior fontanelle 0.3878799854487482 0.5753703007706752 0.5650408855771956 1.0 0.8157590450729751 14 O75381,Q9Y487,P51812 3 +Thin ribs 0.4033497819084284 0.5734258554025453 0.5663563881067386 1.0 0.8168081624079992 13 P50570,Q9Y619,Q32P28,O75431,O14802,Q15813,O95831 7 +Supraventricular arrhythmia 0.3781933632025471 0.5725216553502941 0.5669686191879633 1.0 0.8169244662631457 15 P50402,Q96RR1,Q8WXH0,Q14315,P24468,P00846,P12235,Q8NFF5 8 +Iris coloboma 0.3230749782814964 0.5717816282308007 0.5674699251989002 1.0 0.8171134015101772 30 P78318,O15160,Q10713,Q8IY17,P53701,O96028 6 +Duplication of hand bones 0.2874311671496634 0.5712499990884722 0.5678301901089771 1.0 0.8173723422922359 53 Q9BXW9,Q14739,Q9UM00,P46783,Q8IY17,Q96J42,O75845 7 +Motor delay 0.2513085017865456 0.5697738134942988 0.5688311186679058 1.0 0.8185530392521008 225 Q99720,Q9NZ01,Q03164,P03886,Q15555,Q5BJH7,Q9Y487,Q10713,Q13614,Q9UBB6,Q9UM00,Q9NWM8,Q13868,P51812,Q9H9B1,Q05086,Q68CP9,Q9P2R7,Q96DX4,Q9NUQ7,O75648,Q6P2C8,Q96J02,P61457,Q9BUK6,Q86VD7,Q8N3U4,P51114,Q71SY5,P07196,Q9UP83,O43791,O43819,Q7LGA3,Q96D71,Q9BXJ9,O60313,Q9NSE4 38 +Abnormality of the elbow 0.2866820611965238 0.5690642332709789 0.5693125497943878 1.0 0.818738087456611 58 Q96AY3,Q96DX4,Q99575,Q03164,Q8WXH0,Q96J02,Q15427,Q7LGA3,Q9H6K4 9 +Vitreous hemorrhage 0.4488952322564268 0.5685597911999645 0.569654918449765 1.0 0.818958038901122 3 Q99496 1 +Hepatomegaly 0.2595071417525353 0.5671978333300702 0.5705797799307224 1.0 0.8197253897887952 174 Q9NPL8,P11310,Q16625,O43772,Q6NUQ1,P03886,Q9Y619,Q9NRW7,Q9NP73,Q96HY6,Q10713,O60762,P00846,O43676,O75381,O96011,P31751,P00374,Q96RL7,Q96AA3,Q9HC07,Q9UJW0,P09601,O75845,Q13724,O75648,Q96J02,P83436,Q14739,Q9UP83,P50416,Q96CU9,P34949,O96000,P28070 35 +Male reproductive system neoplasm 0.3853834752415567 0.5629899219597236 0.5734417465365307 1.0 0.8214234198921911 14 P42771,P51809,P38398,Q13423,Q14145,P49959,Q92878 7 +Abnormal basal ganglia mri signal intensity 0.3188406716554279 0.5628260567415228 0.5735533352815794 1.0 0.8214234198921911 32 P00846,P03886,Q9P0J0 3 +Recurrent pneumonia 0.3441030543444889 0.5626932897699575 0.5736437543265758 1.0 0.8214234198921911 21 P78318,P63000,Q71SY5,P50851,Q02809,Q13432,Q92925 7 +Delayed cns myelination 0.3186101976033244 0.5612610331959407 0.5746196014390939 1.0 0.8222968732041962 32 O95831,P49419 2 +Recurrent lower respiratory tract infections 0.3276481067078214 0.560696413344221 0.5750045126744359 1.0 0.8222968732041962 27 P78318,P63000,Q71SY5,P50851,Q02809,Q13432,Q13277,Q9Y5N6,Q92925 9 +Hypoplastic female external genitalia 0.3756527734097791 0.5595501700741468 0.5757863015399385 1.0 0.8225518593427693 15 Q6DKJ4,Q9NP72,Q9Y619,O60216 4 +Incomplete penetrance 0.317883145260231 0.5563356028921207 0.5779814527720342 1.0 0.8252723171896994 32 P00846,P03886 2 +Abnormal dentin morphology 0.5021877163047633 0.5558039779600465 0.578344865819473 1.0 0.8252723171896994 4 Q96AY3 1 +Brachycephaly 0.2808346841480121 0.5556048747297103 0.578480998278764 1.0 0.8252723171896994 68 Q96AY3,Q9UM00,O43791,Q9BZK7,O60566,Q8IY17,Q9NR45,Q9NP72,Q9H9B1,Q05086 10 +Myopathic facies 0.4904564766600139 0.5549196196768269 0.5789496414552611 1.0 0.8252723171896994 7 Q9BUK6 1 +Abnormality of the common coagulation pathway 0.3837406149882723 0.5548958841679894 0.5789658772690651 1.0 0.8252723171896994 14 Q9BZK7,P34949 2 +Disproportionate tall stature 0.3214668029761298 0.5533525904747354 0.5800219960255752 1.0 0.8255399933330568 29 O75648,Q7LGA3,Q6P2C8,Q9NWM8 4 +Decreased head circumference 0.2469104871777134 0.5527562840264619 0.5804303068633658 1.0 0.8255399933330568 452 Q9NPL8,Q99720,Q16625,Q9NZ01,Q15392,O43772,Q03164,P03886,Q15555,Q9Y619,Q5BJH7,Q9NP73,Q9Y487,Q10713,O60762,Q8NC96,Q9NR45,Q96J42,O43676,O75381,Q9BXW9,O96011,Q9UBB6,P00374,Q9UM00,Q9BZK7,Q96AA3,P46783,Q9HC07,P57678,Q05086,O75845,Q9P2R7,Q9NQT5,Q96DX4,Q9NUQ7,P51571,Q14746,O75648,O60566,Q6P2C8,Q9BQP7,Q96F07,P53701,Q8N3U4,P83436,Q15021,O15228,Q8TD30,Q9UEY8,Q71SY5,Q9UP83,O43791,P52732,Q96CU9,Q15427,Q7LGA3,O96000,O95363,Q9Y5P4,Q12824 61 +Proximal muscle weakness in lower limbs 0.3484899589551842 0.550694363407816 0.5818432092165797 1.0 0.8266059203724081 19 P50402,P50570,Q96RR1,Q14315,Q8WXH0,P07196,O95140,Q16637,P36551,P12235,P35670 11 +Widow s peak 0.5006788841451157 0.5504779532132114 0.5819915944384959 1.0 0.8266059203724081 4 O15344,P29372 2 +Localized skin lesion 0.2533159886360988 0.54919072071278 0.5828745717843862 1.0 0.8266818441400342 206 Q15392,Q03164,Q15555,Q9Y619,P06132,Q9BXW9,Q96AY3,Q13126,P48735,Q9H1A4,Q9UM00,P38435,Q9NWM8,P61586,P11802,Q8IZA0,O15269,Q6PGP7,Q9NZ08,P98194,O75648,O60566,Q6P2C8,O15160,P53701,Q8N3U4,Q03518,Q96PU5,Q14739,Q71SY5,O75874,O43791,P52732,Q15427,Q7LGA3,Q9NSE4 36 +Atresia of the external auditory canal 0.3822020278980449 0.5473545784461121 0.5841351542348887 1.0 0.8278597996021989 14 Q9Y619,Q15427,Q9Y5N6,O60216,P21281 5 +Microglossia 0.4996934188328621 0.5470088863977116 0.5843726270287943 1.0 0.8278597996021989 4 P08754,P48651 2 +Reduced consciousness confusion 0.2579597843987972 0.5462658688529862 0.5848831941333805 1.0 0.8281837402798613 125 O43676,P11310,O43772,Q96RR1,P50416,P03886,O43819,Q96CU9,Q13423,O96000,Q96IX5,Q8N3U4,Q12824 13 +Narrow palate 0.3044295856483345 0.5453894734817074 0.5854856786869287 1.0 0.8281837402798613 39 Q68CP9,Q14696,Q9NZ01,Q71SY5,P48651,Q5T160,Q02809,P38398,Q9Y619,Q6W2J9,P51812,O60762,P21281,Q9NP72,P46109,Q969N2 16 +Impairment of activities of daily living 0.2837112086149058 0.544988037908871 0.5857617447807231 1.0 0.8281837402798613 59 Q99720,O96011,P07196,Q9UP83,Q8WWI5,O95363,Q12824 7 +Absent thumb 0.329987935697734 0.5387229894072402 0.5900780083921295 1.0 0.8316905345414893 24 Q9BXW9,Q9NVI1,P08708,Q15427,P46783 5 +Abnormal odontoid tissue morphology 0.3021635254286725 0.5364920734761632 0.591618512650848 1.0 0.8324794300412841 40 Q96AY3,Q5JRA6,Q9H1A4,Q13586,Q9HC07,P53701,P61586 7 +Abnormal circulating long chain fatty acid concentration 0.4960870240497299 0.5358180864499976 0.5920842809790376 1.0 0.8327046857606459 5 O75381 1 +Increased head circumference 0.2710974036974603 0.532530255040074 0.594358792935247 1.0 0.8351257233240287 111 O75381,P11310,Q14739,Q15392,Q99575,Q9H9P8,O96011,Q9UM00,Q12955,O75648,Q6P2C8,Q96J02,Q7LGA3,Q9NP73,Q13555,Q05086,Q8N3U4,Q12824 18 +Distal amyotrophy 0.2827526693393701 0.5308295559112023 0.5955368967611243 1.0 0.8362622883843438 54 Q99720,Q71SY5,Q9BQT8,P07196,Q96RL7,Q13614,Q8IY17,Q9BUK6,O15269 9 +Primary adrenal insufficiency 0.3697882148056197 0.5300285896705544 0.5960921087080435 1.0 0.8363562366119156 15 Q13423,O75381,Q12824 3 +Abnormality of peripheral nerves 0.2974118343442924 0.5297497286414057 0.5962854642999598 1.0 0.8363562366119156 43 Q9P2R7,Q99720,Q71SY5,P07196,Q96RL7,Q13614,O95831,O15269 8 +Premature skin wrinkling 0.3447144460557136 0.5296354325486877 0.5963647227409312 1.0 0.8363562366119156 19 Q9UP83,Q9BZK7 2 +Retinal hemorrhage 0.4932645188363971 0.5280937094160233 0.5974342967181054 1.0 0.8363562366119156 6 Q9Y487 1 +Recurrent fractures 0.3224658564725257 0.5280369556767165 0.5974736863918637 1.0 0.8363562366119156 27 Q96AY3,Q13126,P48735,O75874,Q32P28 5 +Steroid resistant nephrotic syndrome 0.4937238393361711 0.527532877937622 0.5978235910391092 1.0 0.8363562366119156 5 Q12769,Q8WUM0 2 +Abnormal tongue physiology 0.3502233578316294 0.5273142511237414 0.5979753793817444 1.0 0.8363562366119156 17 O95831,Q9NQT5,Q9BQT8 3 +Prolonged partial thromboplastin time 0.4930283134012161 0.5272617315995601 0.5980118452725058 1.0 0.8363562366119156 6 P49257,P38435,O60762 3 +Abnormality of visual evoked potentials 0.3442082960981277 0.5268364029730638 0.5983072009720594 1.0 0.8363562366119156 19 Q9P2R7,Q13724,O60313 3 +Upper limb undergrowth 0.3379006611007227 0.5267413842666383 0.5983731926841542 1.0 0.8363562366119156 21 Q9BXW9,Q14739,Q9NVI1,Q15427,O60762,P98175 6 +Abnormality on pulmonary function testing 0.3497905268118018 0.5250142978476826 0.5995732515895567 1.0 0.8376207933608449 17 Q12824,Q9BQT8 2 +Abnormality of lower limb epiphysis morphology 0.3594535485697125 0.5247184508065258 0.5997789289762481 1.0 0.8376207933608449 16 Q6NUQ1,O95831,Q9NUQ7,Q96DX4 4 +Abnormal tendon morphology 0.2508223432408104 0.5240047767233296 0.6002752175070838 1.0 0.8379805039467149 212 Q99720,P11310,Q15392,Q9Y619,Q9NP73,O60762,P41440,Q96AY3,Q99575,Q96AA3,Q9NQT5,Q8WXH0,Q13586,Q96J02,O95831,Q8N3U4,O15228,Q96PU5,Q96B26,Q71SY5,P07196,Q9UP83,Q7LGA3,P28070,O60313,Q9NSE4 26 +Bronchomalacia 0.4925916991276104 0.523580183425249 0.6005705675165725 1.0 0.8381135030780285 5 Q9H9B1,P63000 2 +Abnormal renal morphology 0.2456028317458507 0.5228041582829018 0.6011105455851025 1.0 0.8381135030780285 234 Q15392,P61619,Q5JRA6,Q03164,P03886,Q10713,P00846,Q9NP72,Q96J42,O75381,Q9BXW9,O96011,P46783,P57678,Q9H9B1,O75845,Q6PGP7,Q68CP9,Q9NZ08,P51571,Q13277,O60566,Q9BQP7,Q9NQH7,P83436,Q9Y5K6,Q71SY5,O43791,O43819,Q15427,Q7LGA3,Q12824 32 +Branchial cyst 0.3827440804411258 0.5208958111238816 0.6024393536376553 1.0 0.8385140497343069 2 P27635 1 +Thick upper lip vermilion 0.4695762218569588 0.5194676479475846 0.6034346678463902 1.0 0.8386528105092564 8 Q08J23,Q9H7D7,O75845 3 +Spastic paraplegia 0.2810131262492288 0.5193254473035409 0.6035338106534605 1.0 0.8386528105092564 58 Q8TD30,Q96CU9,Q8IY17,P00846,O95831,Q9P0J0,Q9BRK0 7 +Genu varum 0.4210990268990514 0.5182117296989386 0.6043105517431686 1.0 0.8394746394960301 11 Q9H1A4,Q96HY6,Q9NUQ7 3 +Serositis 0.3453641060527592 0.516035098424239 0.6058298956247801 1.0 0.8408117117586562 18 Q8NFH4,P52565,Q9Y5K6,Q8N1F7,Q9NZ08,P49327,P38398,Q9P2R3,Q8WUM0,Q14C86,Q12769 11 +Aplasia hypoplasia affecting bones of the axial skeleton 0.2462470966946076 0.5142009039870664 0.6071115358109527 1.0 0.841816730095995 230 Q16625,Q15392,Q03164,Q6NUQ1,Q15555,Q9Y619,Q96HY6,O60762,Q96J42,O75381,Q9BXW9,O96011,Q9UM00,Q96AA3,P46783,P57678,O75845,P51571,O75648,O60566,Q6P2C8,Q9BUK6,O95831,P53701,Q8N3U4,P83436,O15228,Q96PU5,Q14739,O43791,Q15427,Q7LGA3 32 +Multicystic kidney dysplasia 0.3383227023009477 0.5137257982798142 0.607443712425215 1.0 0.8420195891328714 20 O75381,O96011,O43791,O60566,Q96J42 5 +Abnormality of coagulation 0.2798016814127023 0.5133831060083796 0.6076833607254146 1.0 0.8420941034218808 60 O75381,P48735,O96011,Q6NUQ1,P51571,O75874,O75648,Q9Y619,Q9BZK7,P38435,Q96AA3,Q13586,P34949,Q9Y487 14 +Abnormality of vitamin metabolism 0.3255164149878379 0.5119096379106401 0.6087142525756639 1.0 0.8424917702926237 24 P41440 1 +Abnormality of the pharynx 0.2887229755568573 0.5113640638864745 0.6090961534181738 1.0 0.8427628512475038 47 Q13432,Q9NVR5,Q86U42,Q12824,Q03518 5 +Short foot 0.319358056643301 0.5088428099072566 0.6108624094707416 1.0 0.8439192185395198 27 Q9BZK7,Q99496,O60216,Q8N0X7,Q13555,Q9Y4R8,Q15813,Q9Y5P4,Q93009,Q08J23 10 +Abnormality of upper limb epiphysis morphology 0.4043646356908095 0.5088414234594122 0.6108633813666855 1.0 0.8439192185395198 12 P51812,Q5JRA6,O15228 3 +Petechiae 0.404044057858143 0.5074430379286122 0.6118439944600094 1.0 0.8450162484462934 12 Q9BZK7 1 +Diffuse mesangial sclerosis 0.3736817961714163 0.5063062313278981 0.6126416892398583 1.0 0.8454457130205892 14 Q8NFH4,P52565,Q9Y5K6,Q8N1F7,Q9P2R3,Q8WUM0,Q14C86,Q12769 8 +Attenuation of retinal blood vessels 0.476695962655403 0.5048014704813145 0.6136982829033855 1.0 0.8456423587464703 7 P38435,P04439 2 +Abnormality of the zygomatic bone 0.2764164925835241 0.5045205765840672 0.6138956063569823 1.0 0.8456423587464703 73 Q14739,Q96DX4,Q9BZK7,O60566,Q8N3U4,Q15427,Q9HC07,Q9Y487,O15160,O95831,Q9H9B1,P61586 12 +Apnea 0.2783808090296032 0.5040312177904169 0.614239439846967 1.0 0.8456423587464703 81 O43772,O43791,P03886,O43819,Q96CU9,Q6P2C8,Q13724,O60566,O95363,O60313,Q10713,P00846,Q8N3U4,Q9P0J0 14 +Paraplegia 0.2788761920359136 0.5029814976027726 0.6149772807380671 1.0 0.8456423587464703 59 Q8TD30,Q96CU9,Q8IY17,P00846,O95831,Q9P0J0,Q9BRK0 7 +Large beaked nose 0.4866062785683078 0.5028657062549488 0.6150586935306785 1.0 0.8456423587464703 5 O14802 1 +Epistaxis 0.3642688750946489 0.502810547486783 0.6150974772780617 1.0 0.8456423587464703 15 P38435,Q9BZK7 2 +Abnormal lung lobation 0.4026502779864283 0.5013809956891109 0.6161030120070818 1.0 0.8467677925946847 12 O43684,Q14739,O60566,Q969N2 4 +Medulloblastoma 0.4854289806604174 0.5007554603740745 0.6165432351484255 1.0 0.847115818993742 6 Q12824,Q14145 2 +Increased muscle lipid content 0.4308027933584192 0.4999636072754366 0.6171007029180431 1.0 0.8471876905170481 10 Q9BUK6 1 +Overlapping fingers 0.4477353067686156 0.4996310921160314 0.6173348607538027 1.0 0.8471876905170481 9 Q13724,P83436 2 +Encephalopathy 0.2728504856411641 0.4949326882592442 0.6206476356054833 1.0 0.8499920675073037 103 Q8TD30,Q9P2R7,O43676,Q9NPL8,O43772,Q96RR1,P50416,P03886,Q96CU9,Q96N67,O96000,Q96F07,Q8NC96 13 +Caesarian section 0.4842113768577216 0.4935483698284773 0.6216251714164855 1.0 0.850486869983896 4 O60313 1 +Nephritis 0.334054917409835 0.4901212413074866 0.6240481080345486 1.0 0.8526640496808369 20 Q8NFH4,P52565,Q03252,P53621,Q8N1F7,Q9Y5K6,P49327,Q9P2R3,Q8WUM0,Q14C86,P35579,Q12769 12 +Absent earlobe 0.4285289519297942 0.4893506254423975 0.624593485420478 1.0 0.8526640496808369 3 O14802 1 +Craniofacial hyperostosis 0.4829609641483039 0.4893201935381645 0.6246150267978661 1.0 0.8526640496808369 4 P51812 1 +Vertebral fusion 0.4281023100097408 0.4891686653217106 0.6247222915873505 1.0 0.8526640496808369 10 O96028,Q9Y2W2,Q9NVI1 3 +Abnormality of the vestibulocochlear nerve 0.3752838144664286 0.4885224262581276 0.6251798447832213 1.0 0.8527232558710706 2 P10644 1 +Neoplasm of the inner ear 0.3752838144664286 0.4885224262581276 0.6251798447832213 1.0 0.8527232558710706 2 P10644 1 +Hypoventilation 0.4139411602653814 0.4883098471242845 0.625330387638785 1.0 0.8527232558710706 11 O43819,O75380,Q13724 3 +Tall stature 0.2775448561942344 0.4874748992388991 0.6259218265802622 1.0 0.8532729083384254 54 P26196,P80404,O75648,Q6P2C8,Q9NWM8,Q13423,Q7LGA3,O14802,Q9HCK8,O96028,Q9H9B1,P55011 12 +Aplasia hypoplasia of the radius 0.3368828923063376 0.4869962796987229 0.6262609673878223 1.0 0.853478394183765 19 Q9BXW9,Q96AY3,Q9NVI1,Q15427,P98175 5 +Abnormal renal cortex morphology 0.2849630736398116 0.4824585593761151 0.6294802302537348 1.0 0.8574373357749309 47 P00846,Q9NQH7,P03886 3 +Gastritis 0.4805206551256473 0.4821309153419862 0.6297129493880536 1.0 0.8574373357749309 5 Q6PGP7 1 +Abnormal left ventricle morphology 0.3187682506928146 0.4818351487717363 0.629923058158713 1.0 0.8574373357749309 25 P03886,Q13724,Q96RR1 3 +Short palm 0.3295104216635904 0.4796313019077622 0.6314895845564816 1.0 0.8576381617570766 21 Q96DX4,Q15555,Q9Y619,Q9BZK7,Q13555 5 +Colpocephaly 0.4695058109284492 0.4793342078412227 0.6317008901929424 1.0 0.8576381617570766 7 P53701,Q8N3U4,O94979 3 +External ear malformation 0.3380746130437324 0.4774825065837154 0.6330185747517814 1.0 0.8583232276709029 18 O75381,Q9BXW9,O96011,Q9NVI1,Q15555,P38398,Q6W2J9,Q15813 8 +Abnormal cerebral ventricle morphology 0.2452178207256242 0.4771904089495554 0.633226540149262 1.0 0.8583232276709029 224 Q9NPL8,Q16625,Q15392,P49419,O94979,Q9NP73,Q9Y487,Q10713,O60762,P00846,Q9NR45,Q9NP72,Q02218,Q96J42,Q9BXW9,P17480,Q9UM00,Q96RL7,Q9BZK7,P51812,Q9H9B1,Q68CP9,Q9P2R7,O60566,Q9NVR5,O14802,Q96F07,P53701,Q8N3U4,Q71SY5,P42345,Q9UP83,O43819,Q96CU9,Q15427,O95363,P49959,O96028,Q12824 39 +Abnormal saccadic eye movements 0.3158815559827949 0.4755982044961967 0.6343606547994032 1.0 0.8593462219621102 26 P18887,Q96RL7,O43819,P49959,Q8WWI5,Q10713,Q99653 7 +Slow saccadic eye movements 0.3816695284772132 0.4738190854714527 0.6356289234564876 1.0 0.8597787468670913 13 P49959,Q96RL7,Q8WWI5,Q99653 4 +Nasogastric tube feeding 0.3170380432246147 0.4717721355779663 0.6370894419357886 1.0 0.8610679145909119 25 Q71SY5,Q9NUQ7,Q9UBB6,Q9H1A4,Q13724 5 +Decreased specific anti polysaccharide antibody level 0.4234263465282269 0.4702002437137777 0.6382119600465126 1.0 0.8617288163966325 3 P49327,Q9Y2V7 2 +Coloboma 0.2890405868763468 0.4682533330504994 0.6396034366330299 1.0 0.8628787175548635 43 P78318,O15160,Q10713,Q8IY17,P53701,Q9NP72,O96028 7 +Abnormal hair morphology 0.2261537171796 0.463708700890576 0.6428564625384392 1.0 0.8656776977702526 326 Q9H7D7,O94979,P51809,Q03164,P03886,Q15555,Q9Y619,P48449,Q9Y487,P06132,Q10713,Q8IY17,Q9NR45,Q9NP72,Q13126,Q99575,Q9H1A4,Q9UM00,Q9BZK7,Q13868,P46783,P51812,Q9H9B1,P61586,P11802,Q05086,Q6PGP7,Q68CP9,Q9P2R7,Q13724,O75648,Q6P2C8,Q96N67,O15160,O14802,Q96F07,Q9BUK6,O95831,P53701,Q8N3U4,P83436,Q71SY5,P42345,Q9UP83,O43791,O43819,P52732,Q96CU9,Q15427,Q7LGA3,Q13555,Q9Y5P4,O96028,Q9P0J0,Q12824,Q9NSE4 56 +Glioblastoma multiforme 0.4646141655271222 0.4623111415486459 0.6438582109430302 1.0 0.866104444062709 7 O75874,P42771 2 +Abnormal renal physiology 0.2540595199255767 0.4621996718695528 0.6439381385437537 1.0 0.866104444062709 151 O43676,Q9NPL8,Q16625,Q9BXW9,P61619,O43772,P51809,P50416,P03886,O43819,Q9BZK7,Q96CU9,O96000,Q8IY17,Q9NQH7,P09601,P11802 17 +Abnormality of the amniotic fluid 0.2735172532185909 0.4569479674167234 0.6477084453331012 1.0 0.86870439201413 84 Q14739,Q9BXW9,P49419,Q9UP83,O43791,Q9UM00,Q13724,Q70HW3,O60566,Q7LGA3,P06132,Q96J42 12 +Abnormal mitochondrial shape 0.4197548929340727 0.4566086240936016 0.6479523793546615 1.0 0.86870439201413 3 P53597 1 +Lactic acidosis 0.2715176077000279 0.4564057206279567 0.6480982528205641 1.0 0.86870439201413 97 O43676,Q9P2R7,Q6P4A7,Q9NPL8,P49419,P03886,O43819,Q70HW3,Q96CU9,O96000,O95363,P08574,Q86VD7,Q02218 14 +Neoplasm of the male external genitalia 0.4521443686613559 0.455815762091323 0.6485224686634938 1.0 0.86870439201413 8 Q13423,P51809 2 +Generalized hypopigmentation 0.462424676830339 0.454774107134371 0.6492717600222546 1.0 0.8688924883015696 7 O75312,O00203,Q6PGP7 3 +Gaze evoked nystagmus 0.4190173548807678 0.4535654987093143 0.6501415905603942 1.0 0.8695427827689949 10 P41440,Q10713 2 +Ecchymosis 0.3769124475961589 0.4529986380604233 0.6505497222228023 1.0 0.8696730434764042 13 Q9BZK7 1 +Abnormal circulating estrogen level 0.405003134815875 0.4519975054437283 0.6512707795295403 1.0 0.8702821921146954 11 Q12824,P51809 2 +Thick hair 0.4610669427964491 0.4501264406327963 0.6526192726552091 1.0 0.8710563656829986 7 Q9Y487 1 +Unconjugated hyperbilirubinemia 0.4179104477611952 0.4498415655921657 0.6528246843994598 1.0 0.8710738793312379 3 Q9NSD9,O14936 2 +Abnormality of the scrotum 0.278905896171283 0.4478154971189123 0.6542863581564742 1.0 0.8723237998945104 48 P51809,Q9UM00,Q15555,O75648,Q9Y619,O60566,Q6P2C8,Q7LGA3,Q8IY17,Q9NP72 10 +Aortic regurgitation 0.3177397348858359 0.4477423789346554 0.6543391329010035 1.0 0.8723237998945104 23 Q96PU5,Q9H9B1,Q9NZ08,O60566 4 +Proximal amyotrophy 0.3609328955838035 0.4473311345155608 0.6546359902742822 1.0 0.8724627937459543 14 P07196,Q8WXH0,Q13586,Q9BQP7,Q16637,P35637 6 +Abnormality of prenatal development or birth 0.2424891725689054 0.4465929919703975 0.655168956493072 1.0 0.8726660906114025 226 Q9NPL8,P49419,O43772,P03886,Q70HW3,Q9Y487,P06132,Q8NC96,Q96J42,O43676,O75381,Q9BXW9,O96011,Q9UM00,P46783,Q13724,O60566,Q9NVR5,Q96F07,Q14739,Q9UP83,P50416,O43791,Q96CU9,Q15427,Q7LGA3,O96000,Q9Y5P4,O60313 29 +Optic atrophy 0.2490102907277995 0.4455633945542123 0.6559126573511236 1.0 0.8731367434030531 177 Q96RR1,P03886,Q15555,Q9NP73,Q8WWI5,O60762,Q8IY17,P00846,Q8NC96,P41440,Q96J42,O75381,Q9H9P8,O96011,P57678,P61586,Q13724,Q96F07,Q96PU5,P52732,O43819,Q96CU9,Q9H6K4,O60313,Q9P0J0 25 +Abnormal nerve conduction velocity 0.2888093641047551 0.4424940531448058 0.6581317326839518 1.0 0.8744276994016223 40 Q9P2R7,Q99720,Q71SY5,P07196,Q13614,O95831,O15269 7 +Abnormal uvula morphology 0.2865823280173619 0.4420864006468883 0.658426684913672 1.0 0.8744276994016223 42 Q9BXW9,Q15392,P78318,Q9NVI1,P48651,P38398,Q9Y619,Q6DKJ4,Q8N3U4,Q6PGP7 10 +Autistic behavior 0.2453070752715755 0.4374724727763868 0.6617687352182575 1.0 0.8770662289463741 190 Q9NPL8,Q9NZ01,Q96RR1,P03886,Q9NP73,Q8NC96,O43676,P17480,Q9UBB6,Q12955,P51812,Q9H9B1,Q05086,Q96DX4,Q9NUQ7,O75648,Q6P2C8,Q96N67,Q96F07,Q9BUK6,Q8N3U4,Q71SY5,Q9UP83,Q96CU9,Q7LGA3,O96000,Q9BXJ9,Q9P0J0,Q12824 29 +Clumsiness 0.3239571602846131 0.4361726702490729 0.6627114551493558 1.0 0.8778020151539714 20 O43819,Q05086 2 +Sporadic 0.3107274611399303 0.4358990319251271 0.6629099875396205 1.0 0.8778083143976851 25 P42345,P51812,O96028,Q9H9B1,P62263,Q05086 6 +Oligohydramnios 0.2990707721894107 0.4355672781540267 0.663150716099911 1.0 0.877870468712039 32 Q9BXW9,P51114,Q9NVI1,Q9UP83,P38398,O60566,Q7LGA3,Q9Y5P4,Q96J42 9 +Midface retrusion 0.2707852654736537 0.4342043940034933 0.6641400225790581 1.0 0.8784100152651485 82 Q14739,Q99575,Q9UM00,Q9BZK7,O60566,Q15427,Q96J02,Q9NP73,Q9HC07,Q9Y487,P51812,O15160,O95831,P53701,Q9H9B1,Q9NSE4 16 +Abnormal joint morphology 0.2275157909842234 0.4315878214487209 0.6660410113786794 1.0 0.8798966991966806 262 Q15392,P61619,Q5JRA6,Q03164,Q6NUQ1,Q9Y619,Q96HY6,Q9Y487,O60762,Q9NR45,Q9BXW9,Q96AY3,Q99575,Q9H1A4,Q96RL7,P38435,P57678,Q05086,O15269,Q9NZ08,Q9NQT5,Q96DX4,Q9NUQ7,P51571,Q8WXH0,Q96J02,O95831,Q8N3U4,Q9H6K4,Q96PU5,Q14739,Q71SY5,P07196,Q9UP83,Q15427,Q7LGA3,P28070,Q9NSE4 38 +Psychosis 0.2995366101775197 0.4306395494267412 0.6667304795375073 1.0 0.8805507499431219 31 P03886,Q96RR1 2 +Abnormality of the incisor 0.3005812979926974 0.4302138206497168 0.6670401093855456 1.0 0.8807029132954012 30 O75648,Q6P2C8,Q96N67,O95363,Q8N3U4 5 +Bone pain 0.3170314070209923 0.4274343382567041 0.6690630011614007 1.0 0.8826538461301005 22 P48735,Q9BZK7 2 +Bowing of the legs 0.2746416102991596 0.427380407607045 0.669102275410765 1.0 0.8826538461301005 49 Q13126,Q96DX4,Q9NUQ7,Q9H1A4,Q9UP83,Q32P28,Q7LGA3,Q96HY6,Q9NSE4 9 +Abnormality of the small intestine 0.2728722304275613 0.425852350272258 0.6702154378548353 1.0 0.8829227797102233 50 Q9NP73,Q9BT22,Q9BXW9,P50851,P38398,P51812,Q9Y3E5,Q9Y2W2,Q6PGP7,Q9Y5S9,Q13277,O60566,O43684,P98175,Q8N3U4,Q14739,Q9NVI1,P34949,P36551,O96028 20 +Hypokinesia 0.3846286273463375 0.4257608216221167 0.6702821378621322 1.0 0.8829227797102233 12 O95831 1 +Delayed myelination 0.2686860054168762 0.4243409411434864 0.6713171851875768 1.0 0.8829227797102233 77 P49419,Q9UBB6,P00374,Q9UP83,Q96CU9,Q7LGA3,Q13868,Q9NP73,O95831,P57678,P83436,Q05086 12 +Retinal pigment epithelial atrophy 0.4631613112625824 0.4243311966136191 0.6713242907945434 1.0 0.8829227797102233 4 Q8TC12,P50213,O75643 3 +Abnormal enzyme coenzyme activity 0.2453649553995954 0.4224711710954384 0.6726811389195004 1.0 0.8837719139516638 182 P11310,Q16625,O43772,Q96RR1,Q6NUQ1,P03886,P06132,P00846,P41440,Q02218,Q96AY3,Q96RL7,P46783,Q9HC07,P08574,O75845,Q14746,P83436,Q14739,Q9UP83,P50416,P34949,P28070 23 +Patent ductus arteriosus 0.2692681109091729 0.4212914143410756 0.6735422988552215 1.0 0.8846085366108576 90 Q68CP9,Q96PU5,Q9BXW9,Q15392,Q96DX4,P51571,Q9UM00,Q15427,Q9NWM8,O15160,O60762,Q8N3U4,Q12824,Q6PGP7 14 +Abnormality of the basal ganglia 0.2690849772149216 0.4187539962598013 0.6753959289883258 1.0 0.8857995776234594 89 Q9P2R7,Q9NUQ7,Q9UBB6,Q71SY5,P03886,O43819,Q96RL7,Q96CU9,Q96AA3,Q8WWI5,O60313,P00846,Q9NR45,O95831,Q9P0J0 15 +Decreased circulating androgen concentration 0.4258622096189429 0.418528475375689 0.6755607716033847 1.0 0.8857995776234594 9 Q12824 1 +Urogenital sinus anomaly 0.408975122165044 0.4176597960490317 0.6761958708694646 1.0 0.8857995776234594 3 P51809 1 +Metaphyseal widening 0.3260359578707184 0.4166776469149787 0.6769142064969365 1.0 0.8860560870481192 18 O95831,Q9NR45,Q96HY6 3 +Motor seizure 0.2635177650660394 0.4166116340628649 0.6769624982943798 1.0 0.8860560870481192 105 P13073,Q9NZ01,P49419,Q9UBB6,Q9C0E8,Q14746,Q9NUQ7,P03886,O14653,O60566,Q71SY5,Q96N67,Q9Y619,Q9NP73,P00846,Q05086 16 +Cerebellar malformation 0.2684633357440807 0.4155531266908888 0.677737032164289 1.0 0.8863304138133228 55 Q68CP9,Q9NQT5,Q9BZK7,O60566,Q9Y487,Q12824,Q96J42,O75845 8 +Synostosis of metacarpals metatarsals 0.4075275794938359 0.4125431017583622 0.6799413956003157 1.0 0.8880625459414182 3 O60828,P16435 2 +Hepatoblastoma 0.3948855663541182 0.4123760828307704 0.6800637906999514 1.0 0.8880625459414182 11 Q12824,Q6PGP7 2 +Delayed cranial suture closure 0.2982178274604631 0.4111768535635797 0.6809428593719717 1.0 0.8889542227536115 29 O75381,P26196,P48651,Q32P28,O75431,Q9Y487,P51812,O14802,Q93009,Q08J23 10 +Anotia 0.4063663981527237 0.4084587178303359 0.6829369324814611 1.0 0.8896451183992373 3 Q9Y619 1 +Abnormality of upper lip vermillion 0.2447635205523622 0.4083695083086202 0.6830024157968158 1.0 0.8896451183992373 128 Q9H7D7,Q03164,Q9NP73,O60762,P29372,Q9BZK7,Q13868,Q6DKJ4,P51812,Q9H9B1,O75845,Q15907,Q68CP9,Q96DX4,Q05639,P51571,Q6P2C8,O14802,Q96F07,Q8N3U4,Q08J23,Q71SY5,P42345,P52732,Q7LGA3,Q12824 26 +Abnormal thyroid morphology 0.2844705408568235 0.4083139408773781 0.683043205693719 1.0 0.8896451183992373 39 Q68CP9,P42771,P48735,Q96RR1,P50851,O75874,Q96J02,O15160,Q14145,P12235,Q12824 11 +Abnormality of facial soft tissue 0.254490050620839 0.4079259519484419 0.6833280391092145 1.0 0.8897602808751772 116 Q8NFH4,Q96RR1,Q9NP73,Q13614,O75381,O96011,P50570,Q9H1A4,P51812,Q9H553,Q86U42,Q15907,Q9P2R7,Q9BQT8,Q14315,Q9BQP7,O14802,Q9BUK6,Q86VD7,Q8N3U4,Q9Y5K6,P07196,O43819,Q13555,P28070,O60313,Q12824 27 +Pace of progression 0.248914260831659 0.4068233518640665 0.6841377343527155 1.0 0.8905586024763796 158 Q8TD30,Q99720,P61619,Q96RR1,P07196,O14653,Q96RL7,Q13586,Q9BQP7,Q8IY17,O95831,P41440,Q9P0J0,Q86U42,Q9BRK0 15 +Supernumerary nipple 0.3658850730832838 0.40634441255227 0.6844895570347356 1.0 0.8905757181180659 13 Q9UM00,Q8IY17 2 +Aplasia hypoplasia of fingers 0.2662241468742654 0.4058088441046507 0.6848830598511104 1.0 0.8905757181180659 96 P13073,Q03164,Q9NP73,Q9BXW9,P63000,P38398,Q9BZK7,P38435,Q6DKJ4,P46783,P51812,Q68CP9,O95831,Q08J23,P42345,Q9NVI1,Q15427,O96028,Q12824 19 +Sensory axonal neuropathy 0.3426164075810474 0.4019861610660944 0.6876942110638673 1.0 0.892272057933843 15 O95831 1 +Recurrent fever 0.3646728411894715 0.4013597638404854 0.6881552685642152 1.0 0.892272057933843 13 P28070 1 +Abnormality of the bladder 0.2478832888838182 0.4013107940519183 0.6881913174945764 1.0 0.892272057933843 122 Q99720,Q96RR1,Q9UP83,P07196,O43791,Q6P2C8,Q9NWM8,Q8WWI5,P83436,Q12824,Q9BRK0 11 +Cleft soft palate 0.2664656196150046 0.4012832354778277 0.6882116049494145 1.0 0.892272057933843 58 Q15392,Q9Y619,P08708,P62244,Q9Y5N6,P61254,P78318,P48651,O75312,Q6W2J9,Q9NWM8,P46783,Q15813,Q6PGP7,P08754,O14802,Q8N3U4,Q9HC21,P21281 19 +Hemolytic anemia 0.2943909186449002 0.4006116713004874 0.6887060513657433 1.0 0.8926576288088174 31 P41440,Q13586,P09601 3 +Abnormality of the nasal septum 0.4553317102303618 0.4001594133114471 0.6890391061981049 1.0 0.8927101867631204 5 P51812 1 +Asymmetric growth 0.435587336210163 0.3986552613573909 0.6901472370860604 1.0 0.8935029962846109 8 Q15555 1 +Abnormality of the diencephalon 0.3015867224280093 0.3951538757207773 0.6927293302789441 1.0 0.8960776316857844 26 O43819,Q12824,Q96RR1 3 +Anal atresia 0.3013465672711725 0.393866048601752 0.6936799377345295 1.0 0.8965392633202336 26 Q9BXW9,Q9NVI1,P29372,P38398,P53701,Q9H9B1 6 +Lymphopenia 0.3041655073119954 0.3923546958163348 0.6947961553251893 1.0 0.8970539437530494 24 Q13432 1 +Saccadic smooth pursuit 0.4518216723406455 0.3892714314983477 0.6970753673170844 1.0 0.8986811231081739 5 Q10713 1 +Bruising susceptibility 0.2933477202832441 0.3888109900017394 0.6974159704316227 1.0 0.8986811231081739 30 Q9BXW9,P38435,Q9BZK7,Q9NWM8 4 +Abnormal cranial nerve morphology 0.2640014639873936 0.3877267533001166 0.6982182553182339 1.0 0.8987962775177054 62 Q9P2R7,O75381,Q96RR1,P07196,O43819,Q9BQP7,Q13614,Q86U42,Q12824 9 +Abnormality of the breast 0.2590691056368574 0.3874779504756322 0.6984024054883715 1.0 0.8987962775177054 107 P48735,P31751,P51809,O75874,Q9UM00,Q15555,Q9BZK7,Q96AA3,Q9Y619,Q7LGA3,O14802,O60762,Q8IY17,P49959,Q9NP72,P11802,P83436,Q9Y5P4 18 +Ketosis 0.3114603211337204 0.3850052631336522 0.7002335161342956 1.0 0.9006410641931741 21 P11310 1 +Abnormality of the metacarpal bones 0.2819027501830614 0.3841424291304317 0.7008728855632582 1.0 0.9006990230335713 37 Q9H1A4,Q14739,Q96DX4,Q32P28 4 +Decreased circulating cortisol level 0.4160219300657073 0.3841394849552335 0.7008750675923485 1.0 0.9006990230335713 9 Q13423 1 +Left ventricular hypertrophy 0.3080192673491453 0.3809681561743425 0.7032268776069204 1.0 0.9034506517160764 22 P03886 1 +Aplasia hypoplasia of the spleen 0.4301684109253988 0.3807144976168625 0.7034151100667994 1.0 0.9034506517160764 8 Q9NVR5,Q96J42 2 +Facial edema 0.3014611281863683 0.3783181400293904 0.7051942713019805 1.0 0.9035467618786628 24 Q9H1A4,Q9Y5K6,P28070 3 +Aphthous ulcer 0.4478983804415619 0.3781959064352423 0.7052850662258172 1.0 0.9035467618786628 6 P49327,P78527,Q9NZ08 3 +Gonadal neoplasm 0.2980687141757848 0.3765110523676342 0.7065370003752589 1.0 0.9041406364288622 26 Q13423,O75874,P48735,P51809 4 +Astrocytoma 0.4136946079113858 0.3762125061075164 0.7067589187084817 1.0 0.9041406364288622 9 P48735 1 +Poor suck 0.3009425742646762 0.3756574087511522 0.7071716053655694 1.0 0.9041406364288622 24 O43819,Q8N3U4,Q05086 3 +Dilated fourth ventricle 0.2791541092740732 0.3751599127119902 0.7075415415078468 1.0 0.9041406364288622 39 Q68CP9,O60566,Q9Y487,Q10713,O14802,Q96J42,Q12824 7 +Abnormality of the dentition 0.238399839769058 0.3717477332378922 0.7100806818608321 1.0 0.9055487284385004 216 Q5JRA6,Q03164,Q15555,Q9Y619,Q9NP73,Q9Y487,P06132,Q8NC96,Q96AY3,Q99575,Q9H1A4,Q9UM00,Q9BZK7,Q9HC07,P51812,Q9H9B1,P61586,Q05086,Q68CP9,Q96DX4,P51571,O75648,Q13586,Q6P2C8,Q96N67,O15160,Q96F07,P53701,Q8N3U4,Q14739,Q7LGA3,O95363,Q9Y5P4,Q12824 34 +Abnormality of the periorbital region 0.2608188111425011 0.3701473205252923 0.7112727253626934 1.0 0.9066025452709626 65 Q8NFH4,O75381,Q9Y5K6,O96011,O43791,P52732,Q96N67,Q9NP73,Q7LGA3,P51812,P28070,Q9HCK8,P98175,Q08J23,P38159,Q6PGP7 16 +Hyperpituitarism 0.3103720327824082 0.3682401847467667 0.7126941491368157 1.0 0.9078215713342368 20 Q9BUK6,Q12824,P51809 3 +Abnormal acetabulum morphology 0.3179716459520411 0.3680575596170036 0.7128303155046094 1.0 0.9078215713342368 17 Q6NUQ1,Q9NR45,Q96AY3 3 +Meningocele 0.410198199175499 0.3644571206596407 0.7155166878975998 1.0 0.9095094629959096 9 O75845 1 +Stomatitis 0.3414062459639965 0.3634811589872367 0.7162454848477033 1.0 0.9095094629959096 14 Q9BZK7 1 +Abnormal iliac wing morphology 0.3943632020895605 0.3630660195520477 0.7165555676118605 1.0 0.9095094629959096 10 O95831,Q9NR45 2 +Thyroid carcinoma 0.3142646474207282 0.36104817838488 0.7180634315506891 1.0 0.910228074401882 18 Q68CP9,Q12824,Q14145 3 +Exodeviation 0.2965837566338181 0.3606060673730428 0.7183939529952899 1.0 0.9103005893898358 25 O43819,Q05086 2 +Breech presentation 0.423249203084725 0.3583925634748802 0.7200495560483449 1.0 0.910654146296352 8 O60313 1 +Upper motor neuron dysfunction 0.2267338042299681 0.357811511895378 0.7204843749517602 1.0 0.9106783564948622 366 Q99720,Q16625,Q9NZ01,Q15392,Q92804,P03886,Q9Y619,Q5BJH7,Q9NP73,Q8WWI5,Q15165,Q9Y487,Q10713,O60762,Q8IY17,P00846,Q8NC96,P41440,O75381,Q9H9P8,O96011,Q9UBB6,Q12955,Q96AA3,Q9BRK0,Q9P2R7,Q9NZ08,Q9NQT5,Q9NUQ7,Q14746,Q6P2C8,Q13423,Q96F07,O95831,Q8N3U4,Q8TD30,Q9UEY8,Q96B26,Q71SY5,P07196,P50416,O43819,O43791,Q96CU9,P52732,O95363,Q96D71,Q9H6K4,Q99653,O60313,Q9P0J0,Q12824 52 +Abnormality of the coagulation cascade 0.2744134470631267 0.3565957011937302 0.7213944961384029 1.0 0.9106783564948622 41 Q6NUQ1,P51571,O75648,P38435,Q9Y619,Q9BZK7,Q96AA3,P34949,Q9Y487 9 +Incisor macrodontia 0.3132821061623497 0.3565888262624215 0.7213996436390113 1.0 0.9106783564948622 18 O95363,O75648,Q6P2C8 3 +Abnormal incisor morphology 0.3132821061623497 0.3565888262624215 0.7213996436390113 1.0 0.9106783564948622 18 O95363,O75648,Q6P2C8 3 +Abnormal peripheral action potential amplitude 0.4075508619403373 0.3556812830168648 0.7220792635906816 1.0 0.9106783564948622 9 Q96RL7 1 +Abnormal oral physiology 0.260001425299108 0.3556738844771858 0.7220848049399182 1.0 0.9106783564948622 60 Q8TD30,Q14739,Q92804,Q96RL7,Q9BZK7,Q6P2C8,Q9NP73,O95363,Q15165,O14802,P51812,Q9Y5P4,Q05086 13 +Abnormality of the nasal tip 0.258311140998938 0.3544985980353055 0.7229652545124412 1.0 0.9112671671179884 101 O75845,Q71SY5,Q03164,O43791,P52732,Q9BZK7,Q96N67,Q7LGA3,Q13868,Q9NP73,Q9Y487,P51812,O95831,Q8N3U4,Q12824 15 +Limb hypertonia 0.2766218507464333 0.3529326935583781 0.7241389000826404 1.0 0.91196808934511 37 Q14739,P17480,Q05639,O14802,O00400,Q96F07,Q8NC96 7 +Breast hypoplasia 0.4395897987260103 0.3523114609193193 0.7246046939075657 1.0 0.9120475863854604 4 Q9Y5N6,Q9Y619 2 +Frontal cortical atrophy 0.31395024084789 0.3501353747592186 0.72623710391268 1.0 0.9125555108121426 17 Q96RL7,O75648,Q6P2C8 3 +Abnormality of the spinal cord 0.2567868928075139 0.3493570752388937 0.7268212545276402 1.0 0.9125555108121426 68 Q9BXW9,Q96RR1,P07196,Q13217,Q10713,O96028,O00400,Q8IY17,Q12824,Q08J23,O75845 11 +Cardiomegaly 0.2818801643559919 0.34485728321219 0.730201665825392 1.0 0.9154117161211262 33 P50416,P11310 2 +Triangular mouth 0.4366988101241418 0.3440031646451792 0.7308439061380214 1.0 0.9154117161211262 5 Q10713,O60566 2 +Abnormality iris morphology 0.256049007399533 0.3439360164936551 0.7308944050859314 1.0 0.9154117161211262 70 Q10713,Q8IY17,Q96J42,O75381,Q9BXW9,P78318,O96011,P38398,Q6W2J9,Q9H553,P61586,Q05086,P26196,Q13586,O15160,P53701,Q9NVI1,Q7LGA3,O96028 19 +Oculomotor apraxia 0.3004164657688434 0.3439088588365753 0.730914829406206 1.0 0.9154117161211262 22 Q9Y3C8,Q9NQT5,P18887,P36405,Q10713,O00429,P49959,O96008 8 +Deviation of the hand or of fingers of the hand 0.2538269219658608 0.3431699223221323 0.7314706307753736 1.0 0.9158086828934832 107 Q14739,Q9BXW9,Q96DX4,Q71SY5,Q5JRA6,Q03164,Q9UP83,O43791,Q9H6K4,Q13724,O60566,Q15427,Q9Y619,Q8IY17,Q8N3U4,P83436,Q05086 17 +Cerebellar vermis atrophy 0.4035667895810984 0.3426812296344795 0.7318382852261389 1.0 0.9158086828934832 9 Q99653,Q10713 2 +Generalized onset seizure 0.2530954504345253 0.3422248531834057 0.7321816830517307 1.0 0.915860476629624 108 Q9NZ01,P49419,P03886,Q9Y619,Q9NP73,O60762,P00846,Q9UBB6,P00374,O14653,P51812,Q9H9B1,Q05086,Q9NUQ7,Q14746,O60566,Q96N67,Q71SY5,P42345,Q9C0E8,O94979 21 +Glioma 0.3496392553006693 0.3420888504599528 0.7322840278923837 1.0 0.915860476629624 13 P48735 1 +Depressed nasal ridge 0.3073751578134384 0.3410447625613922 0.7330698839355758 1.0 0.9165902771813852 19 Q8N3U4,Q96J42,O60566 3 +Exercise intolerance 0.2790755803150047 0.3373765720736122 0.7358330432332982 1.0 0.9185493542847728 34 Q9BQP7,P03886,Q96RR1 3 +Early onset of sexual maturation 0.2720233155993824 0.3373496511380753 0.7358533348122385 1.0 0.9185493542847728 40 P48735,Q5JRA6,O75874,O75648,Q6P2C8,Q7LGA3,Q13423,Q9H9B1 8 +Puberty and gonadal disorders 0.2413221137835807 0.3368931798499809 0.7361974267964468 1.0 0.9187257144319296 146 Q5JRA6,Q96RR1,P51809,P03886,Q15555,P48449,Q8IY17,Q9NP72,Q9BXW9,P48735,Q9H1A4,Q9H9B1,O75648,Q6P2C8,Q13423,Q9BQP7,O15160,O14802,O75874,Q7LGA3,O96028,P49959,O60313,Q12824 24 +Severe muscular hypotonia 0.2821047688762049 0.3336912387255594 0.7386125614981938 1.0 0.9200859596752916 31 O95831,O75381,Q8TD30,Q9NWM8 4 +Abnormal glucose homeostasis 0.2367355537106233 0.3335632004484055 0.7387091910240695 1.0 0.9200859596752916 183 O43676,P11310,P49419,O43772,Q96RR1,P50416,P03886,Q15555,Q96CU9,P34949,Q13423,O96000,Q8IY17,P00846,P83436,Q9NSE4 16 +Abnormal soft palate morphology 0.2545382272780677 0.3326178813330466 0.739422743883406 1.0 0.920721558491432 70 Q15392,Q9Y619,P08708,P62244,Q9Y5N6,P61254,Q9BXW9,Q9BUF5,P78318,P48651,O75312,P38398,Q6W2J9,Q9NWM8,P46783,Q6DKJ4,Q15813,Q6PGP7,P08754,O14802,Q8N3U4,Q9NVI1,Q9HC21,Q15427,P21281 25 +Tics 0.4238716624769837 0.3313721084563476 0.7403634301241808 1.0 0.9211332981220924 7 Q96RL7 1 +Congenital malformation of the right heart 0.4141996949478332 0.3302333998296285 0.7412236116847362 1.0 0.9215212446544512 8 Q9NVR5,P24468,Q8N3U4 3 +Abnormality of the peripheral nervous system 0.2572403096448365 0.3301514592166968 0.7412855221900265 1.0 0.9215212446544512 95 Q9P2R7,Q99720,Q9BXW9,Q71SY5,Q96RR1,P07196,Q96RL7,Q13724,Q9Y619,Q15427,O60313,Q13614,O95831,P41440,Q8N3U4,O15269 16 +Abnormal spermatogenesis 0.3593009006193328 0.3293205757315688 0.7419133935318032 1.0 0.921795850987128 12 Q13423,P51809 2 +Hypoglycemic seizures 0.4133772207843982 0.3277341579178143 0.7431126742380778 1.0 0.922274086109176 8 Q13423 1 +Limited extraocular movements 0.4224830480066731 0.3272867484640366 0.7434510142257968 1.0 0.9224412748405532 7 Q99653,O43819 2 +Aplasia hypoplasia involving forearm bones 0.2965569127380618 0.3258886262001559 0.7445086213349967 1.0 0.9230327556408752 22 Q9BXW9,Q96AY3,Q9Y5S9,Q9NVI1,P38398,Q15427,P98175,Q969N2 8 +Abnormal salivary gland morphology 0.4288720050734123 0.321676070065409 0.7476981083781065 1.0 0.923844320302096 5 Q02218 1 +Hypoplasia of the uterus 0.4111483475919491 0.3210126854415195 0.7482007776661681 1.0 0.923844320302096 8 P53701,Q16740 2 +Abnormal hair quantity 0.2344248302270674 0.3204059759590913 0.7486605959887405 1.0 0.923844320302096 209 P51809,Q03164,P03886,Q15555,Q9Y487,P06132,Q8IY17,Q9NR45,Q9NP72,Q99575,Q9H1A4,Q9UM00,Q13868,Q9H9B1,P61586,Q6PGP7,Q68CP9,Q9P2R7,Q13724,O75648,Q6P2C8,Q96N67,O15160,Q9BUK6,P83436,Q71SY5,O43791,O43819,Q96CU9,Q15427,Q9Y5P4,Q9P0J0,Q12824 33 +Azoospermia 0.368119900980138 0.3161014635614023 0.7519254958951662 1.0 0.9261406830910256 11 Q13423,P51809 2 +Joint hypermobility 0.2561360815145719 0.3149554813881883 0.75279545554503 1.0 0.9261406830910256 89 Q96PU5,Q96DX4,Q03164,Q9UM00,O75648,Q9Y619,Q6P2C8,Q9NWM8,Q7LGA3,Q9Y487,P51812,Q05086 12 +Ovarian neoplasm 0.2986900267920664 0.3145702840739025 0.753087944385368 1.0 0.9261406830910256 20 P42771,P48735,P51809,O75874,P38398,Q14145,P49959,P43246,Q92878 9 +Corpus callosum atrophy 0.3137500314905991 0.3143208886591166 0.7532773347449586 1.0 0.9261406830910256 16 Q9H9P8 1 +Bifid nasal tip 0.3776234331802484 0.3134992036930407 0.7539014255833361 1.0 0.9261406830910256 3 Q6W2J9 1 +Ectopia lentis 0.4085932865419752 0.3134007681119758 0.7539762007276916 1.0 0.9261406830910256 8 Q03519,Q03518,Q6W2J9 3 +Primary amenorrhea 0.2881174784061042 0.3131385220281825 0.7541754233737199 1.0 0.9261406830910256 24 Q9BUK6,Q96RR1 2 +Optic nerve hypoplasia 0.3134537524714422 0.313135797035194 0.7541774935775314 1.0 0.9261406830910256 16 Q8N3U4,P07196 2 +Abnormality of reproductive system physiology 0.2363940879490069 0.312467540790629 0.7546852276789602 1.0 0.9264834908904308 135 Q96RR1,Q9H1A4,P51809,P03886,Q15555,Q9BZK7,Q13423,Q9BQP7,Q9NVR5,Q8IY17,Q9BUK6,Q12824 12 +Chronic infection 0.3649521138461514 0.3056034982157964 0.7599065566432346 1.0 0.9303538424210916 11 Q9BZK7 1 +Thick nasal alae 0.3264812406383423 0.3054023892552465 0.7600597023002227 1.0 0.9303538424210916 14 Q68CP9,Q12824,P51812,P61586 4 +Severe intrauterine growth retardation 0.4227302073717431 0.3048398786828215 0.760488107343785 1.0 0.9304524326620413 4 O14802 1 +Aplasia hypoplasia affecting the eye 0.2547405109538708 0.3047082321113035 0.7605883792820174 1.0 0.9304524326620413 85 Q9BXW9,Q71SY5,P07196,O43791,Q15555,P52732,Q13586,Q9BZK7,Q96N67,O60566,Q7LGA3,O15160,O14802,P61586,P53701,Q9NP72,Q8N3U4,Q96J42 18 +Abnormality of the outer ear 0.2145857412554134 0.3035993330670041 0.7614331597473321 1.0 0.9308153257744696 324 Q16625,Q15392,Q03164,Q15555,Q9Y619,Q9NP73,Q9Y487,Q10713,Q8IY17,Q9NR45,Q9NP72,Q96J42,O75381,Q9BXW9,O96011,Q9UM00,Q9BZK7,Q13868,P46783,Q9HC07,P51812,Q9H9B1,Q6PGP7,Q68CP9,Q96DX4,P51571,O75648,O60566,Q6P2C8,Q96N67,Q96J02,O15160,O95831,P53701,Q8N3U4,P83436,Q8TD30,Q14739,Q71SY5,Q9UP83,O43791,P52732,Q15427,Q7LGA3,Q13555 45 +Abnormal number of incisors 0.421743425117381 0.3024301403151124 0.7623241811644177 1.0 0.9310672797721252 6 Q8N3U4 1 +Oral cleft 0.2375902449284611 0.3002077990883563 0.7640186564829574 1.0 0.9312680647890136 152 Q9H7D7,Q15392,Q15555,Q9Y619,P08708,P62244,Q9Y5N6,Q10713,Q96J42,Q9BXW9,P63241,P61254,P78318,P29372,P48651,Q9UM00,P38398,O75312,Q9NWM8,Q6W2J9,Q6DKJ4,P36405,P46783,Q15813,Q9Y2W2,Q6PGP7,Q68CP9,Q9Y5S9,P08754,O60566,O43684,O15160,O14802,P98175,Q8N3U4,Q08J23,Q96PU5,Q14739,Q71SY5,Q9NVI1,Q9HC21,O43791,Q5JPH6,Q15427,Q7LGA3,O15344,O60216,P21281,O96028,P46109 50 +Hyperconvex fingernails 0.4207285985197952 0.2996707606401729 0.7644283037809483 1.0 0.9312680647890136 6 O96028,P51812 2 +Abnormality of circulating glucocorticoid level 0.350536239027955 0.2989797296799251 0.7649555119381721 1.0 0.9312680647890136 12 Q13423 1 +Gliosis 0.2661366582880456 0.297844130290242 0.765822131121686 1.0 0.931556088661842 38 Q9H9P8,O43819,O95363,Q10713,P00846 5 +Congenital sensorineural hearing impairment 0.4199980668872125 0.2973224991680617 0.7662203060384158 1.0 0.931556088661842 5 Q16740 1 +Decreased facial expression 0.2800210863917778 0.2963205989188677 0.7669852563030886 1.0 0.9319858398747294 27 Q86U42,Q05086,Q96RR1 3 +Incomitant strabismus 0.3090949925845556 0.2960013177980887 0.7672290750132311 1.0 0.9320321023893636 16 O75648,Q6P2C8,Q7LGA3 3 +U shaped upper lip vermilion 0.4180311876965207 0.2922592113567679 0.7700884426105767 1.0 0.9335029823457084 4 O60762 1 +Prominent nose 0.2862115679372935 0.2915156191593737 0.7706570000002926 1.0 0.9337857954149882 23 Q9UP83,Q8N3U4,Q13586 3 +Abnormal finger phalanx morphology 0.2366077368923757 0.29119830567708 0.7708996583272758 1.0 0.9337857954149882 157 Q5JRA6,Q03164,Q9Y619,Q9NP73,Q8IY17,Q96J42,Q9BXW9,Q9H1A4,Q9UM00,P38435,Q13868,P46783,O75845,O75648,Q6P2C8,Q14739,Q71SY5,Q9UP83,Q15427,Q7LGA3,Q12824 21 +Abnormal erythrocyte enzyme level 0.2975475536857546 0.2893280741803732 0.7723303304824407 1.0 0.9347198496087248 18 Q96RL7 1 +Mesomelia 0.4088641174586089 0.2886787432373543 0.7728272309107036 1.0 0.9348568858706892 7 Q14739,Q6DKJ4 2 +Diminished movement 0.2926396608869896 0.2886407610147116 0.7728562996877995 1.0 0.9348568858706892 20 P51114,Q96RR1,Q14203,O95831,P12235,Q96QK1 6 +Carcinoma 0.4165584415584434 0.2881661948222145 0.7732195243196873 1.0 0.935046568384459 5 O60832,P43246,Q07864,P28340 4 +Large forehead 0.4071775993867436 0.2840868191832719 0.7763438477853546 1.0 0.936181793858996 7 O43791 1 +Morphological abnormality of the pyramidal tract 0.2843227423849451 0.2833524631212534 0.7769066646094858 1.0 0.936181793858996 23 P00846,O95831,Q9H9P8,Q9Y619 4 +Cranial asymmetry 0.4146018405136421 0.2833133178657813 0.7769366691616968 1.0 0.936181793858996 6 O14802 1 +Bone marrow hypercellularity 0.3698353892364107 0.2831956306824081 0.7770268775314877 1.0 0.936181793858996 10 Q9BZK7 1 +Paresthesia 0.2913204742077109 0.2831634365537829 0.7770515551677317 1.0 0.936181793858996 20 Q9H6K4,P06132,P07196 3 +Gonadal dysgenesis 0.3696434128278913 0.2826144668720525 0.7774723893003423 1.0 0.936439756322933 10 Q96RR1 1 +Vertebral segmentation defect 0.2767952659420186 0.2817610598253219 0.778126731385369 1.0 0.9366816391342012 27 P63241,Q9Y5S9,Q9NVI1,Q9UM00,Q9Y619,Q6DKJ4,O96028,O60216,Q8N3U4,Q9Y2W2 10 +Abnormality of the calvaria 0.2203876313337525 0.2815494677413452 0.7782889920512577 1.0 0.9366816391342012 251 P13073,Q15392,Q03164,Q9Y619,Q9Y487,Q10713,O60762,Q8IY17,Q9NR45,Q9NP72,O75381,Q96AY3,Q9BXW9,O96011,Q9UM00,Q9BZK7,Q32P28,P51812,Q9H9B1,Q05086,O75845,Q6PGP7,Q68CP9,Q96DX4,Q13724,O60566,Q6P2C8,Q96J02,O15160,Q96F07,O95831,Q8N3U4,O15228,Q14739,O43791,P52732 36 +Lymphedema 0.3689928711428074 0.2806503924497056 0.7789785610841098 1.0 0.9372570734956222 10 Q14739,P52732 2 +Tracheomalacia 0.344516123582981 0.2791167349558888 0.7801552406607981 1.0 0.93785595650515 12 Q9H9B1,Q9H7D7,P63000 3 +Finger clinodactyly 0.2506882482234562 0.2787776816306556 0.7804154431849937 1.0 0.93785595650515 82 Q9BXW9,Q96DX4,Q5JRA6,Q03164,Q9UP83,O43791,O60566,Q9Y619,Q8IY17,Q8N3U4,Q05086 11 +Limited elbow movement 0.2619696122090874 0.2765284643741856 0.7821422002284739 1.0 0.9391446689890494 38 Q96AY3,Q96DX4,Q8WXH0,Q96J02,Q15427,Q9H6K4 6 +Cafe au lait spot 0.2590125962896071 0.2751006267618084 0.7832389300667328 1.0 0.9399422347807354 42 Q9BXW9,P26196,P42345,Q9NVI1,Q9H1A4,P55011,P38398,O75648,O60566,Q6P2C8,Q7LGA3,P43246,Q9Y2W2,Q6PGP7 14 +Abnormality of the musculature of the lower limbs 0.2795397500063584 0.2750404057332333 0.7832851956506128 1.0 0.9399422347807354 24 P00846,Q96RL7,P07196 3 +Supernumerary bones of the axial skeleton 0.4105740748105962 0.2726231923290365 0.7851428821312321 1.0 0.9399422569011424 5 O75431 1 +Cone shaped epiphysis 0.3803292507247133 0.2720929676396814 0.7855505366441147 1.0 0.9400912339060276 9 O95831,Q96DX4 2 +Prominent forehead 0.2484317110542906 0.2709824477823315 0.7864045320045501 1.0 0.94019860912658 77 Q14739,Q15392,P52732,Q6PGP7,O75648,Q6P2C8,Q7LGA3,Q10713,P51812,Q9NR45,Q9NSE4 11 +Abnormality of the lymph nodes 0.2666439293227953 0.2687512660675155 0.788121097958832 1.0 0.940239107204544 33 Q13586,Q9BZK7,P28070 3 +Retrognathia 0.2495019981517747 0.2686389399779222 0.7882075436416973 1.0 0.940239107204544 86 Q68CP9,Q16625,Q15392,Q71SY5,Q5JRA6,Q9UP83,Q13724,Q9Y619,Q15427,Q7LGA3,O95363,O15160,P53701,P83436 14 +Encephalocele 0.3287972283723425 0.2683937338319769 0.7883962623144563 1.0 0.940239107204544 13 Q96J42,Q10713 2 +Centrally nucleated skeletal muscle fibers 0.3924780260719829 0.2677623723690631 0.7888822358897398 1.0 0.940239107204544 8 P51114,Q13586 2 +Microdontia 0.2749882448767411 0.2668980028954011 0.789547694347168 1.0 0.940239107204544 26 Q9H1A4,Q9UM00,Q15555,Q7LGA3,Q9Y487,P61586 6 +Myelodysplasia 0.2573790063018513 0.2667119568350621 0.7896909470862872 1.0 0.940239107204544 42 Q9BXW9,P42771,Q9NVI1,Q9H1A4,P38398,O60566,P08708,P62244,O43684,P46783,P62263 11 +Lissencephaly 0.2496813497799632 0.2665334907205243 0.7898283700582713 1.0 0.940239107204544 49 Q16625,Q15392 2 +Equinovarus deformity 0.4003522403050245 0.265942488247664 0.7902835020651611 1.0 0.940239107204544 7 Q96RL7 1 +Talipes valgus 0.407659850697829 0.2655451000818074 0.7905895715986995 1.0 0.940239107204544 4 O00754,P49589,Q9H2M9 3 +Agenesis of corpus callosum 0.2482707406787117 0.265162724617879 0.7908841087978571 1.0 0.9403425230588696 80 Q68CP9,Q9BXW9,Q15392,P78318,Q71SY5,P29372,O94979,P03886,P80404,O60566,Q7LGA3,O14802,Q10713,Q9H9B1,O96028,P53701,Q8N3U4,Q12824 18 +Abnormal elasticity of skin 0.246228490612846 0.2646540867420037 0.7912759500256878 1.0 0.940561546475037 60 Q15555,P38435,Q9BZK7,Q9NWM8,O96000,Q9Y487 6 +Abnormality of mouth size 0.232449020426421 0.2643803347677759 0.7914868631804519 1.0 0.9405654486378404 121 Q15392,Q15555,Q9Y619,Q9Y487,Q9UM00,P51812,Q05086,Q6PGP7,Q68CP9,P51571,O75648,Q6P2C8,O15160,O14802,P83436,Q15427,Q7LGA3,Q12824,Q9NSE4 19 +Hernia 0.2283625044165792 0.2620388966342374 0.7932914544296861 1.0 0.94221559742173 130 Q15555,Q9Y487,Q10713,Q9BXW9,Q9UM00,Q32P28,Q9NWM8,P51812,Q9H9B1,Q6PGP7,Q68CP9,P53701,Q8N3U4,Q96PU5,Q14739,Q71SY5,P42345,P24468,O96028,Q12824 20 +Abnormality of salivation 0.2507965645682511 0.2602890847717169 0.794640791602105 1.0 0.9427011003943244 47 Q8TD30,Q14739,Q92804,Q96RL7,Q6P2C8,Q9NP73,Q15165,O14802,P51812,Q9Y5P4,Q05086 11 +Symptomatic seizures 0.3759707310593876 0.2599004142385067 0.7949405917348793 1.0 0.9427011003943244 9 Q13423 1 +Fatty replacement of skeletal muscle 0.4044109270736388 0.2572789259289848 0.7969634596914998 1.0 0.9432430757223598 6 Q8NFF5 1 +Increased connective tissue 0.3875661614014629 0.2546935701301518 0.798959782805964 1.0 0.9442441471721932 8 O95831,P31751,P07196 3 +Attention deficit hyperactivity disorder 0.2466684000362859 0.2535255507492382 0.7998621193113475 1.0 0.944817575092674 93 Q9BXW9,Q9H1A4,Q9UM00,P52732,O75648,Q6P2C8,Q7LGA3,Q9NP73,P51812,Q96F07,Q9BXJ9,Q8NC96,Q8N3U4,Q05086 14 +Aplasia hypoplasia affecting the fundus 0.2855663560264465 0.250936850420579 0.8018629332013492 1.0 0.9459476790109664 19 Q9NVI1,P07196,O43791,Q9NVI7,O14802,Q8N3U4 6 +Aplasia hypoplasia of the optic nerve 0.2855663560264465 0.250936850420579 0.8018629332013492 1.0 0.9459476790109664 19 Q9NVI1,P07196,O43791,Q9NVI7,O14802,Q8N3U4 6 +Stroke 0.2650456101052208 0.2498958031513937 0.8026679288819829 1.0 0.945985355692697 30 P03886,Q13586 2 +Decreased muscle mass 0.3035696237885366 0.2492557826207667 0.8031629323893319 1.0 0.9460197512961496 15 Q9NP72,Q9Y487 2 +Abnormal anatomic location of the heart 0.3347567131705746 0.2486731646474227 0.8036136083875394 1.0 0.9462527293548976 12 Q9NVR5,Q96J42 2 +Metopic synostosis 0.3549643088903315 0.2479018130902439 0.8042103770455395 1.0 0.9462527293548976 3 Q16531,P61978 2 +Cervical ribs 0.354964308890325 0.2479018130902264 0.8042103770455531 1.0 0.9462527293548976 3 Q9UHX1,Q9Y5S9 2 +Abnormality of chromosome segregation 0.393133266147489 0.2475335194642024 0.8044953536644031 1.0 0.9463422363281604 7 Q14739 1 +Hyperkinetic movements 0.3430891649649722 0.2388201902476288 0.8112450136202163 1.0 0.9525505214358684 11 Q9P2R7 1 +Congenital malformation of the great arteries 0.2373431368402183 0.2384376642382434 0.8115416578106174 1.0 0.9526519071992996 110 Q68CP9,Q96PU5,Q9BXW9,Q15392,Q96DX4,P51571,Q9UM00,Q15427,Q9NWM8,Q9NVR5,O60762,Q9H9B1,Q8N3U4,Q12824,Q6PGP7 15 +Toe clinodactyly 0.2677785579974214 0.2375052611289892 0.8122648381669015 1.0 0.9532298501338546 26 Q96DX4,O75648,Q6P2C8,Q7LGA3,Q9NP73 5 +Malignant hyperthermia 0.3509678498547431 0.2372603168455169 0.8124548457763383 1.0 0.9532298501338546 3 P50570 1 +Hyperconvex nail 0.380468438775853 0.2365276438223191 0.8130232590618223 1.0 0.9534589188837432 8 P51812,O96028,Q9Y619 3 +Abnormal circulating hormone concentration 0.2443624633744889 0.2364660631155925 0.8130710383328699 1.0 0.9534589188837432 88 P51809,Q03164,Q15555,P34949,Q13423,Q8IY17,Q8N3U4,Q12824,Q9NSE4 9 +Receptive language delay 0.284155405854749 0.2331619508644062 0.8156356504300761 1.0 0.955634539393134 17 P26196,O75648,Q6P2C8,Q7LGA3,Q9H9B1 5 +Abnormality of the synovia 0.2427312499862118 0.2323474740694537 0.8162681421824751 1.0 0.955634539393134 79 Q9BXW9,Q96AY3,Q9NQT5,Q6NUQ1,Q8N3U4,Q15427,Q9Y487,Q9NR45,P57678,Q9NSE4 10 +Abnormal fallopian tube morphology 0.3784750444335369 0.231580741132812 0.8168636672597385 1.0 0.955634539393134 8 P53701,P49959,P38398,Q92878 4 +Reduced forced vital capacity 0.3935203439436406 0.2315487933905491 0.8168884835186647 1.0 0.955634539393134 4 Q9BQT8 1 +High narrow palate 0.2628701661794274 0.2310882073598044 0.817246276363504 1.0 0.955634539393134 28 Q68CP9,Q71SY5,P48651,Q02809,Q9Y619,Q6W2J9,Q9Y5N6,O60762,Q96T58,P46109,Q969N2 11 +Biparietal narrowing 0.3859256460725553 0.2299743510838888 0.8181117004489573 1.0 0.956152219564958 7 O75845 1 +Anemia of inadequate production 0.2397434930608 0.2296492929039691 0.8183643001655279 1.0 0.956197568643606 65 Q9BXW9,Q6P4A7,P00374,Q9BQT8,P46783,P41440,O60313 7 +Brachydactyly 0.2394545497173815 0.2292595806717066 0.8186671668043899 1.0 0.956197568643606 71 Q14739,Q99575,Q96DX4,Q13868,Q13555,P51812,Q8IY17,O95831,Q9H9B1,P61586,Q9NSE4 11 +Severe postnatal growth retardation 0.3273673934266298 0.2271126205711733 0.8203361706552099 1.0 0.957516839234244 12 P27635,O76024,P54132,Q6KC79,Q92979,Q9UQE7,O60885,O95202,O60216,O96028,Q13363 11 +Abnormality of the anus 0.2472499382060744 0.2265865791454592 0.8207452291773352 1.0 0.9575474216018536 44 Q9BXW9,Q9NVI1,P29372,P48651,P38398,Q6W2J9,Q6DKJ4,P53701,Q08J23,Q9H9B1 10 +Scapular winging 0.2747001388421094 0.2197784920239749 0.826043670982588 1.0 0.9607131783186454 20 Q8WXH0,Q9Y487,P07196 3 +Shawl scrotum 0.3880780275393985 0.2187307555919264 0.8268597895486027 1.0 0.9610406581846168 6 Q9UM00,Q9Y619 2 +Abnormal magnesium concentration 0.3878328074743008 0.2182263129625706 0.8272527843240636 1.0 0.9610406581846168 5 P61457 1 +Skin tags 0.2763857552000797 0.2181265100726155 0.8273305426253295 1.0 0.9610406581846168 19 Q15427,Q6W2J9,O15160,O96028,Q8N3U4,Q9Y2W2 6 +Renal hypoplasia aplasia 0.2390793810780104 0.2179614019629012 0.8274591851630613 1.0 0.9610406581846168 75 Q9BXW9,Q15392,O43819,Q15427,P46783,P57678 6 +Dyslexia 0.3876538093068628 0.2177830556034855 0.8275981473682539 1.0 0.9610406581846168 6 Q13586 1 +Hyperreflexia 0.2184462924821344 0.2161143591164007 0.8288986072290212 1.0 0.9620575687285334 233 Q99720,Q16625,P13073,P03886,Q15555,Q9Y619,Q8WWI5,Q10713,O60762,Q8IY17,P00846,O75381,Q9BXW9,O96011,Q96AA3,Q96IX5,Q05086,Q9BRK0,Q9NZ08,Q9NQT5,Q9BQT8,Q96F07,O95831,Q8TD30,Q14739,Q9UP83,Q96CU9,O95363,Q9H6K4,Q99653,O60313,Q9P0J0 32 +Abnormal hair pattern 0.231167561229822 0.2140657914408932 0.8304957519160867 1.0 0.9634254399794124 113 Q9NR45,Q9NP72,P29372,Q9UM00,Q9BZK7,P46783,Q68CP9,O75648,Q6P2C8,Q96N67,O15160,P98175,O95831,Q8N3U4,Q08J23,P83436,Q9UP83,O43791,Q7LGA3,O96028,Q12824 21 +Skin rash 0.2777906558514773 0.2120463630204834 0.8320708641829804 1.0 0.9634254399794124 17 P28070 1 +Melanoma 0.274458124443108 0.2116396178856292 0.8323881987708464 1.0 0.9634254399794124 19 P42771,Q9H1A4,P38398,P49959,P11802,Q92878 6 +Aplasia hypoplasia of the ear 0.2359564038074655 0.210701736988051 0.833120019113947 1.0 0.9634254399794124 55 Q96DX4,O43791,Q15555,Q9Y619,Q15427,P46783,O15160,Q8N3U4,Q6PGP7 9 +Sensory ataxia 0.3843687748031762 0.2106106662360608 0.833191088546908 1.0 0.9634254399794124 5 Q96RR1 1 +Absent testis 0.3841623971762801 0.2101626629551638 0.8335407194099376 1.0 0.9634254399794124 5 Q9BXW9,Q9NVI1 2 +Abnormal circulating iga level 0.3324093584519078 0.20996799248647 0.8336926544634209 1.0 0.9634254399794124 11 P50851,Q13724,P42345,Q96J02 4 +Abnormal cornea morphology 0.22420388990272 0.2087580151213393 0.834637148230041 1.0 0.9642709210614856 148 Q16625,Q15555,P06132,Q96J42,O75381,Q9BXW9,O96011,Q9BZK7,Q9NWM8,Q13868,P61586,O75845,Q9NZ08,O75648,O60566,Q6P2C8,P53701,Q14739,Q71SY5,P52732,Q9Y5Z9,Q9NSE4 22 +Restlessness 0.2522335394319174 0.2083874300227562 0.8349264702881976 1.0 0.9643592326378212 33 P52732,P49419,Q92804,O96008 4 +Simplified gyral pattern 0.2533575504830187 0.2027309616863815 0.8393453217306077 1.0 0.96798225749482 29 O43791,Q12824,Q6P2C8,P52732 4 +Abnormal number of erythroid precursors 0.2631268551996035 0.2020318561502709 0.8398918200448042 1.0 0.96836598238813 23 P46783,P06132 2 +Somatic mutation 0.248087072490706 0.2011498778223909 0.8405813820780079 1.0 0.9684885781927668 35 P42345,Q92804,P30154,O75874,P38398,O60566,Q07812,Q13492,P61586,P62263,Q12824 11 +Abnormality of the cheek 0.2336024570027237 0.1993731352672355 0.8419708735714633 1.0 0.9685444533465536 55 Q9P2J5,Q9H7D7,Q9Y487,O60762,Q96J42,Q00535,O75312,Q9BZK7,Q6W2J9,Q15813,Q9Y2W2,O75845,O15160,P35573,Q8N3U4,P52732,Q15427,O75431,O96028 19 +Premature ovarian insufficiency 0.2732034647188937 0.1977136208509867 0.8432691321868675 1.0 0.9686240932854157 17 Q96RR1 1 +Abnormality of the upper respiratory tract 0.2371754880086317 0.1976274297575539 0.8433365722113457 1.0 0.9686240932854157 91 Q14739,Q96DX4,Q92804,Q13432,Q96HY6,Q9NVR5,P28070,Q86U42,Q12824,Q03518 10 +Muscular hypotonia of the trunk 0.2355741976946241 0.197246564370182 0.8436345932121005 1.0 0.9686240932854157 76 Q96PU5,Q16625,Q9NQT5,Q99653,Q5BJH7,O95363,O60313,Q9Y5P4,Q8NC96,Q8N3U4 10 +Tented upper lip vermilion 0.257891276448921 0.1967866618913209 0.8439944892947566 1.0 0.9686240932854157 25 Q96DX4,Q71SY5,Q6DKJ4,O60762,Q96F07,Q15907 6 +Thickened nuchal skin fold 0.3508552451163717 0.196514062590033 0.8442078269012692 1.0 0.9686240932854157 9 O75381 1 +Self mutilation 0.3377337600138785 0.1962785197283502 0.8443921731532242 1.0 0.9686240932854157 10 Q9UM00,Q96RL7 2 +Atrial arrhythmia 0.3369756316902551 0.1944831625721785 0.8457975783487206 1.0 0.969990640486001 10 P50402,Q96RR1,Q14315,P24468,P12235 5 +Absent speech 0.2266651657699488 0.1938720526312252 0.8462760672614873 1.0 0.9702937445443022 114 Q8TD30,Q96PU5,Q15021,P17480,Q9NQT5,Q71SY5,Q9C0E8,Q9UM00,Q9BZK7,Q8N3U4,O95363,Q96F07,O00400,Q12824,P57678,Q05086 16 +Abnormality of the musculature of the hand 0.2469078958473105 0.1925365955940111 0.8473219049746106 1.0 0.9710954320681604 34 P61254,Q9BQT8,P07196,Q14315,Q14203,Q13586,P08708,P62244,Q8TB36,Q9Y6X9,P46783,O95140 12 +Abnormality of skull ossification 0.3140086271155425 0.191489126494996 0.8481423987183263 1.0 0.9711306866509292 12 Q32P28 1 +Autosomal dominant germline de novo mutation 0.3319273199221227 0.1905910908772019 0.8488459706955767 1.0 0.9711306866509292 3 P24928,Q9HCK8 2 +Exaggerated cupid s bow 0.3605410748252303 0.190198461193291 0.8491536169023146 1.0 0.9711306866509292 8 Q71SY5,Q6P2C8,Q96KP1,Q6DKJ4,Q969N2 5 +Abnormality of skeletal maturation 0.2353864239318928 0.1899488152513226 0.8493492397057547 1.0 0.9711306866509292 93 Q68CP9,P13073,Q99575,Q9UHD1,Q96DX4,Q03164,Q9H1A4,P51809,Q9Y619,Q96J02,P51812,Q9BUK6,O95831,Q99653,O96028,Q12824 16 +High palate 0.2174100713379232 0.1862525313622778 0.8522467305235368 1.0 0.9729951436055684 202 Q16625,Q96RR1,Q03164,Q9Y619,Q9Y487,O60762,Q9NP72,O75381,Q9BXW9,O96011,Q9UBB6,Q9UM00,P46783,P51812,P57678,O75845,Q68CP9,Q13724,O75648,Q6P2C8,Q9BUK6,O95831,Q8N3U4,O15228,Q71SY5,P07196,Q9UP83,O43791,Q7LGA3 29 +Ectopic anus 0.2828049206619721 0.1859892214191515 0.8524532139156427 1.0 0.9729951436055684 15 P53701,Q6DKJ4,P48651 3 +High myopia 0.3573971341457455 0.1835309116274377 0.8543814667009717 1.0 0.9729951436055684 8 Q9Y487 1 +Cryptorchidism 0.2173537245023072 0.1832560908546439 0.8545970853225076 1.0 0.9729951436055684 181 P51809,Q15555,Q9Y619,P48449,Q9Y487,Q8IY17,Q9NP72,Q96J42,O75381,Q9BXW9,P78318,P63000,P50570,P29372,P48651,Q9H1A4,P38398,O96011,Q9BZK7,Q5KU26,Q6W2J9,Q6DKJ4,Q9H9B1,Q68CP9,P26196,O75648,O60566,Q6P2C8,Q13423,O15160,O14802,P98175,Q08J23,Q96PU5,P51114,P42345,Q9NVI1,Q9UP83,Q7LGA3,O95363,O96028,Q12824 42 +Persistent head lag 0.3702500811951961 0.181296405789698 0.8561349270480028 1.0 0.9729951436055684 6 Q15233,P51608,P53597,Q5XKP0,Q9NSD9 5 +Neoplasm of striated muscle 0.3636853973567573 0.1811230000798169 0.8562710317096476 1.0 0.9729951436055684 7 P42771,O60566,Q14145 3 +Rhabdomyosarcoma 0.3636853973567573 0.1811230000798169 0.8562710317096476 1.0 0.9729951436055684 7 P42771,O60566,Q14145 3 +Abnormal conus terminalis morphology 0.3561910952226073 0.1810200815044647 0.8563518136427672 1.0 0.9729951436055684 8 Q9H3P2,P35222,Q5H8A4,O95202,O96028,Q13363,O60341 7 +Hip dislocation 0.2304004636629649 0.1808481577015789 0.8564867619020666 1.0 0.9729951436055684 61 Q9NQT5,Q8N3U4,Q15427,Q9Y487,P57678,Q9NSE4 6 +Abnormality of the lens 0.2163996015902931 0.1807428957239153 0.8565693873239191 1.0 0.9729951436055684 201 Q16625,Q96RR1,P03886,Q15555,Q10713,Q8IY17,Q9NP72,Q96J42,O75381,Q9BXW9,Q13126,O96011,Q9H1A4,P46783,P51812,O00400,P57678,P61586,Q9H9B1,O75845,Q9NZ08,O60566,Q6P2C8,O15160,P53701,O15228,Q03518,Q71SY5,P52732,Q7LGA3,Q9H6K4,O60313,Q9NSE4 33 +Functional intestinal obstruction 0.3695977553921754 0.1807065577328474 0.8565979112062745 1.0 0.9729951436055684 4 P42771 1 +Extrahepatic cholestasis 0.3695977553921754 0.1807065577328474 0.8565979112062745 1.0 0.9729951436055684 4 P42771 1 +Peritoneal abscess 0.3695977553921754 0.1807065577328474 0.8565979112062745 1.0 0.9729951436055684 4 P42771 1 +Abnormal patella morphology 0.2516026491209491 0.1804565297561681 0.8567941783317026 1.0 0.9729951436055684 26 Q96PU5,Q96AY3 2 +Fatigable weakness of swallowing muscles 0.3201663234243624 0.180058619113787 0.857106548745663 1.0 0.97310593128267 11 Q15165,P35637,Q92804 3 +Prominent supraorbital ridges 0.3302753836833587 0.1791445869791435 0.8578241729034306 1.0 0.9736626707940887 10 P51812,Q9HCK8 2 +Facial hypotonia 0.3193838083294253 0.1782631933211375 0.8585162832704829 1.0 0.9736626707940887 11 Q13555,Q8N3U4 2 +Abnormality of the nasal alae 0.2188363620977626 0.1766971397463704 0.8597462876768995 1.0 0.9736626707940887 161 Q16625,Q15392,Q15555,Q9NP73,Q9Y487,Q10713,Q9NP72,O75381,O96011,Q9BZK7,Q13868,P51812,Q9H9B1,P61586,O75845,Q6PGP7,Q68CP9,O60566,Q6P2C8,Q96N67,O95831,O15228,Q71SY5,O43791,P52732,Q7LGA3,Q9Y5P4,Q12824 28 +Abnormal vena cava morphology 0.3412749014211548 0.1755138747457368 0.8606758695276389 1.0 0.9741675666269624 9 Q9NVR5,Q71SY5 2 +Bilateral polymicrogyria 0.3607605114086911 0.175308471071383 0.8608372558957462 1.0 0.9741675666269624 7 Q05639,P67870,P42356 3 +Omphalocele 0.3280786275453401 0.1743228474337207 0.8616117444846629 1.0 0.97455710424857 10 Q14739 1 +Vertebral clefting 0.3526465109211635 0.1737914267990943 0.8620293822871681 1.0 0.97466459429534 8 Q8N3U4 1 +Abnormal eyebrow morphology 0.2179580197705724 0.173654379484009 0.8621370925698517 1.0 0.97466459429534 153 Q9H7D7,Q03164,Q10713,Q8IY17,Q9NR45,Q9H1A4,Q9UM00,P51812,Q9H9B1,Q68CP9,O75648,Q6P2C8,Q96N67,O14802,Q96F07,O95831,Q8N3U4,Q71SY5,O43791,Q15427,Q7LGA3,Q13555,Q9Y5P4,O96028,Q12824,Q9NSE4 26 +Abnormal eyelid morphology 0.2014117444664608 0.1724653786777617 0.8630716773115596 1.0 0.9754777191171072 333 Q15392,O94979,Q03164,Q15555,Q9Y619,P48449,Q9NP73,P26640,Q9Y487,P06132,Q10713,O60762,Q8IY17,Q9NR45,Q8NC96,Q9NP72,O75381,Q9BXW9,P78318,O96011,Q9UBB6,P29372,Q9H1A4,Q9UM00,Q9BZK7,Q13868,P46783,Q6DKJ4,P51812,Q9H553,Q9H9B1,P61586,Q05086,O75845,Q6PGP7,Q68CP9,Q15907,Q96DX4,Q05639,Q13724,O75648,O60566,Q6P2C8,Q96N67,P80404,O15160,O14802,Q96F07,P98175,P53701,Q8N3U4,Q08J23,P83436,P61981,Q71SY5,P42345,O43791,P52732,Q15427,Q7LGA3,Q13555,Q9Y5P4,O96028,Q12824 64 +Cleft upper lip 0.242162512307837 0.1706755582038593 0.8644788825343344 1.0 0.9763374066019782 32 Q9UM00,O43791,Q15427,O15160,O96028,Q8N3U4 6 +Deeply set eye 0.2275495083390572 0.1692645268853783 0.8655885767851696 1.0 0.9771034769092496 67 P51571,O43791,Q13586,Q9BZK7,Q05086,Q9NSE4 6 +Abnormality of ocular smooth pursuit 0.2547444350322166 0.1685591816342856 0.8661433893972059 1.0 0.9772876913611388 22 P41440,O14802,Q10713 3 +Intellectual disability moderate 0.2302653288961666 0.1676113784211148 0.8668890191596121 1.0 0.9773791675979778 79 Q68CP9,Q15021,Q9NZ01,Q96DX4,Q9UBB6,Q9NUQ7,Q9UP83,Q71SY5,Q12955,Q9NP73,Q10713,P51812,Q8N3U4,Q12824 14 +Abnormal external genitalia 0.1927423298017776 0.1673084631350536 0.8671273453810757 1.0 0.9773791675979778 281 Q15392,P51809,Q15555,Q9Y619,P48449,Q9Y487,Q10713,O60762,Q8IY17,Q9NP72,Q96J42,O75381,Q9BXW9,P78318,O96011,P50570,P29372,Q9H1A4,Q9UM00,Q9BZK7,P46783,Q9H9B1,O75845,Q6PGP7,Q68CP9,Q9NZ08,P51571,Q13724,O75648,O60566,Q6P2C8,Q13423,O15160,O14802,Q14145,P53701,Q96PU5,P51114,Q71SY5,P42345,Q9UP83,Q7LGA3,O95363,P24468,O96028,Q12824 46 +Fused cervical vertebrae 0.3617449976184927 0.1651846369891004 0.868798657060214 1.0 0.9785325500951688 6 Q9Y2W2,Q9NVI1 2 +Prostate neoplasm 0.3475073384159022 0.1637107614518986 0.8699588454394167 1.0 0.9789293576535268 8 P42771,P38398,P49959,Q92878 4 +Aplasia hypoplasia of the hallux 0.2549767220917009 0.1634860871773326 0.8701357266017458 1.0 0.9789293576535268 21 P26196,O75648,Q6P2C8,Q7LGA3,O96028 5 +Abnormal hand morphology 0.2185468579681891 0.1634253046807986 0.8701835804542379 1.0 0.9789293576535268 116 Q68CP9,P13073,Q9BXW9,Q71SY5,P42345,Q03164,Q13724,Q9BZK7,P38435,Q9NP73,P46783,O14802,P51812,O95831,P83436,Q12824 16 +Fatigable weakness of respiratory muscles 0.3017630336158462 0.1626955881875372 0.8707581208241555 1.0 0.9789293576535268 12 Q15165,P35637,Q92804 3 +Eclabion 0.2408879114800363 0.1626659656052696 0.8707814455295138 1.0 0.9789293576535268 29 Q9H7D7,Q71SY5,Q9BZK7,Q96N67,P51812,Q9H9B1 6 +Proptosis 0.2236638231871137 0.161494829409179 0.871703683440689 1.0 0.9789293576535268 52 Q9BXW9,Q96DX4,Q9NVI1,P38398,Q32P28,Q96J02,Q6DKJ4,O96028,Q8N3U4,Q12824,Q6PGP7 11 +Abnormal ovarian physiology 0.2560280817767165 0.1614707377975744 0.8717226567651388 1.0 0.9789293576535268 20 Q96RR1 1 +Neoplasm of the breast 0.2404676302942761 0.1614539538631274 0.8717358749794268 1.0 0.9789293576535268 29 P42771,P48735,O75874,P38398,P49959,P43246,P11802,Q92878 8 +Beaking of vertebral bodies 0.3214735558595238 0.1604422260321494 0.8725327288669731 1.0 0.9789293576535268 10 Q6NUQ1,Q96DX4 2 +Truncal ataxia 0.2587396734377915 0.1601990758613169 0.8727242573490102 1.0 0.9789293576535268 18 Q9UP83,Q96CW1,O14802,P19525,Q9BUK6 5 +Peripheral neuropathy 0.2146487814168041 0.1586895648752016 0.8739134600189538 1.0 0.9792666810011188 155 Q9NPL8,Q96RR1,P03886,Q10713,O60762,Q8IY17,P00846,P41440,Q9NP72,O96011,Q96RL7,O15269,Q9P2R7,O95831,P07196,O43819,Q96CU9,O60313,Q9P0J0,Q9NSE4 20 +Posterior pituitary dysgenesis 0.3166774821544394 0.1581506704837774 0.8743380737069537 1.0 0.9792666810011188 3 Q9UHX1,P42356 2 +Depression 0.2279780932645493 0.1580435832694499 0.8744224557725222 1.0 0.9792666810011188 95 Q9NZ01,Q92804,Q96RR1,P03886,Q14203,Q15165,Q9UBB6,Q96RL7,P51812,Q9H9B1,O43681,Q9NUQ7,Q96C86,Q5JTZ9,Q9BUK6,P12235,Q8N3U4,Q08J23,P55011,P35670,Q6DKK2,Q71SY5,P35637,P36551,P43246,Q96QK1 26 +Amenorrhea 0.2368271355270788 0.1567524232860311 0.8754399699177413 1.0 0.9798873285804413 33 Q9BUK6,Q12824,Q96RR1 3 +Arthropathy 0.3566094995692092 0.1562114240432063 0.8758663721971331 1.0 0.9798873285804413 5 O15269 1 +Abnormal uvea morphology 0.2283913464251809 0.1558764001420438 0.8761304478609833 1.0 0.9798873285804413 87 Q9Y619,Q10713,Q8IY17,Q96J42,O75381,Q9BXW9,P78318,O96011,P50851,P38398,Q6W2J9,Q9H553,P61586,Q05086,P26196,P04439,Q13586,O15160,P53701,Q9NVI1,P52732,Q7LGA3,O96028 23 +Focal non motor seizure 0.3432366091536661 0.1556936301559545 0.8762745183398162 1.0 0.9798873285804413 8 Q05639,P67870,P42356 3 +Erythroid hypoplasia 0.2566580911824183 0.1548285301439705 0.8769564986157166 1.0 0.9799242572099646 18 P61254,P18077,P08708,P62244,P46783,P42766,P62263 7 +Amblyopia 0.2638763590466593 0.1538255111468806 0.8777473182503694 1.0 0.9803172652038126 16 P53701,P52732,Q71SY5 3 +Ovarian carcinoma 0.3550794340716905 0.1535590501393959 0.8779574271372776 1.0 0.9803172652038126 5 P42771 1 +Very long chain fatty acid accumulation 0.35474992796321 0.1527848675163682 0.878567931592573 1.0 0.9807572030838728 6 O75381 1 +Abnormal circulating albumin concentration 0.2388432629223404 0.1520113542124906 0.8791779803598667 1.0 0.98119641562705 28 Q8NFH4,Q9Y5K6,Q5XKP0,P34949,Q8WUM0,Q16854,Q14C86,Q9BT22,Q12769,Q6PGP7 10 +Abnormality of toe 0.2119306455486183 0.1511218994343772 0.8798795576417606 1.0 0.9816264665788828 173 Q99720,P13073,Q5JRA6,Q03164,Q9NP73,Q10713,Q96J42,Q9BXW9,Q9UM00,Q9BZK7,P61586,O75845,Q96DX4,O75648,Q6P2C8,Q96J02,Q96PU5,Q14739,Q71SY5,P07196,Q15427,Q7LGA3,Q9Y5P4,Q99653 24 +Long foot 0.306371568705632 0.1504595085645722 0.8804020945038229 1.0 0.9816264665788828 11 P51812 1 +Choanal stenosis 0.3124594419208246 0.1499640846282959 0.8807929510794339 1.0 0.9816264665788828 3 P16435,P48651 2 +Abnormality of periauricular region 0.2516951063952545 0.1499195681357704 0.8808280730582179 1.0 0.9816264665788828 20 Q15427,Q6W2J9,O15160,O96028,Q8N3U4,Q9Y2W2 6 +Chronic kidney disease 0.2342936940981053 0.1476650525847631 0.8826071132149398 1.0 0.9821585209501928 32 Q9NQH7 1 +Calvarial hyperostosis 0.3511846802986104 0.1474744573552391 0.8827575393537597 1.0 0.9821585209501928 4 P22626,P09651,P10644 3 +Abnormal mitochondrial morphology 0.3266701943114742 0.146932843673116 0.8831850277572744 1.0 0.9821585209501928 9 Q9BQP7 1 +Emg myopathic abnormalities 0.2367767061517623 0.1465442959105823 0.8834917242514937 1.0 0.9821585209501928 28 P51114,P50570,Q96RR1,P07196,Q8WXH0,Q13586,Q9BUK6 7 +Fatiguable weakness of proximal limb muscles 0.3507924417167061 0.1463203321818123 0.8836685158355575 1.0 0.9821585209501928 5 Q13586 1 +Thin vermilion border 0.2054213219343874 0.1459717639002411 0.8839436787806041 1.0 0.9821585209501928 128 O75845,Q68CP9,Q03164,O43791,P52732,O75648,Q9BZK7,Q6P2C8,Q7LGA3,Q13868,Q9NP73,Q96HY6,O14802,P51812,Q8N3U4,Q12824,Q9NSE4 17 +Distal upper limb muscle weakness 0.3504810445281459 0.1458055847826649 0.8840748670053085 1.0 0.9821585209501928 5 Q14315,Q9Y6X9 2 +Secondary microcephaly 0.2229424335423059 0.1454330604393434 0.8843689636788974 1.0 0.9821585209501928 72 Q8TD30,Q9NQT5,P00374,Q14746,Q96CU9,Q9HC07,Q9Y487,O60762,Q9Y5P4,P83436,Q05086 11 +Phthisis bulbi 0.3497015393726004 0.1443126758333875 0.8852535692167509 1.0 0.9824102568720924 6 O60216,Q6W2J9 2 +Pulmonary artery dilatation 0.2706193329946839 0.1422695913633459 0.8868670647490864 1.0 0.9829967710578325 14 P26196,O75648,Q6P2C8,Q7LGA3 4 +Abnormality of the midface 0.209835918024694 0.1417652011204548 0.8872654718808104 1.0 0.983106412170303 152 Q9NP73,Q9Y487,O60762,Q96J42,Q99575,Q9UM00,Q9BZK7,Q9HC07,P51812,Q9H9B1,P61586,O75845,Q96DX4,O60566,Q96J02,O15160,O14802,O95831,P53701,Q8N3U4,Q14739,P42345,P52732,Q15427,O96028,Q9NSE4 26 +Abnormal prostate morphology 0.323601662263811 0.1414530713943156 0.8875120307930815 1.0 0.983106412170303 9 P42771,P38398,P49959,Q92878 4 +Supernumerary tooth 0.3350078115315448 0.1411647075423597 0.8877398261344873 1.0 0.983106412170303 8 Q6DKJ4,P21281,Q6W2J9 3 +Difficulty running 0.2696289662340977 0.1401933561545011 0.8885072210859968 1.0 0.9834929445668904 14 Q13586,Q9H553,P07196 3 +Distal sensory impairment of all modalities 0.3466309501862892 0.1395646959408509 0.8890039361104047 1.0 0.9835790253293822 5 O15269 1 +Abnormality of the fetal cardiovascular system 0.3456669912366183 0.1385231722764293 0.8898269573247131 1.0 0.9835790253293822 4 P26196,O60826,P16435 3 +Talipes equinovarus 0.2229253243713155 0.1380958390991629 0.8901646741886631 1.0 0.9835790253293822 78 Q15392,Q6NUQ1,Q9Y619,Q9Y487,Q13614,Q96AY3,Q9UM00,Q9NWM8,Q6W2J9,Q9Y3E5,Q9H9B1,O75845,Q15907,Q03001,Q8TB36,P42356,P98175,P49902,Q15427,O96028,O94979 21 +Redundant skin 0.2408750339839004 0.1376138176367239 0.8905456345388449 1.0 0.9835790253293822 23 Q9Y487,P38435 2 +Abnormal thorax morphology 0.2058198388141299 0.1371730790413749 0.8908939895493742 1.0 0.9835790253293822 216 Q03164,Q15555,Q9Y619,Q96HY6,Q9Y487,Q96AY3,P17480,Q99575,Q9UM00,Q32P28,P46783,P51812,O75845,Q96DX4,Q8WXH0,Q13724,O75648,O60566,Q6P2C8,Q96J02,Q9BUK6,O95831,Q96PU5,Q14739,Q71SY5,P07196,Q15427,Q7LGA3,O60313,Q9NSE4 30 +Abnormal jaw morphology 0.1851119626497888 0.1370868224526071 0.8909621682889524 1.0 0.9835790253293822 284 Q16625,Q15392,Q5JRA6,Q15555,Q9Y619,O60762,Q9NP72,Q96J42,O75381,Q9BXW9,O96011,Q9UM00,Q96RL7,Q96AA3,P46783,P51812,P57678,Q9H9B1,Q05086,O75845,Q68CP9,P51571,Q13724,O75648,O60566,Q6P2C8,O15160,Q9BUK6,P53701,Q8N3U4,P83436,O15228,Q96PU5,Q14739,Q71SY5,Q9UP83,O43791,P52732,Q15427,Q7LGA3,O95363,Q9NSE4 42 +Slender build 0.2977805553873339 0.1342116971472104 0.8932351766111817 1.0 0.9849574769018772 11 Q3ZCQ8,O14802,P17252 3 +Myopia 0.2213800487917647 0.1341140489771729 0.8933123905291884 1.0 0.9849574769018772 96 Q9H7D7,Q15555,P26640,Q9Y487,Q9NWM8,Q13868,Q9H582,P61586,Q05086,Q68CP9,O15160,O14802,P98175,P12235,Q08J23,P49902,P52732,O43819,Q13555,Q12824 20 +Abnormal scalp morphology 0.2145071260780845 0.1328574035063222 0.8943061552587996 1.0 0.9849574769018772 110 P48449,P06132,Q9NR45,Q9NP72,Q9UM00,Q9BZK7,P46783,P61586,Q68CP9,Q96N67,O15160,O14802,O95831,Q8N3U4,P83436,Q71SY5,Q9UP83,O43791,Q7LGA3,O96028,Q12824 21 +Gastrointestinal hemorrhage 0.2294146953147454 0.1327313266201957 0.8944058669967971 1.0 0.9849574769018772 29 Q14739,P34949 2 +Broad thumb 0.2311027239519716 0.1325833968873008 0.8945228638503739 1.0 0.9849574769018772 28 P26196,O75648,Q6P2C8,Q7LGA3,Q13868,Q6DKJ4,Q08J23 7 +Glucose intolerance 0.2186406069955154 0.1320841335663934 0.8949177455313588 1.0 0.9849574769018772 102 O43676,Q9NPL8,Q5JRA6,P31751,Q96RR1,P03886,Q15555,Q96CU9,Q13217,Q96J02,P61457,O96000,Q8IY17,P00846,O60313 15 +Highly arched eyebrow 0.2184505087687854 0.1319354226202309 0.8950353703220966 1.0 0.9849574769018772 63 Q10713,P63000,Q9UM00,Q5KU26,Q6W2J9,P36405,P51812,Q9H9B1,P26196,O75648,Q6P2C8,Q96F07,Q8N3U4,P55011,Q8NB90,O43791,Q7LGA3,Q13555,O60216,O96028,P46109 21 +Cutis marmorata 0.2468209977176458 0.1315802217151885 0.8953163302740486 1.0 0.9849574769018772 18 Q8WVM7,Q6KC79,Q4G0J3,P48651,Q9C0B1,O75792,Q9UBM7,Q9UQE7,Q9Y3Z3,O60885,P31153,P55265,P51812,O60216,Q08J23,P09884,Q14683 17 +Poor speech 0.2211407500532652 0.1315043377056257 0.8953763553823244 1.0 0.9849574769018772 78 Q9NZ01,Q9NUQ7,Q9UBB6,Q71SY5,Q96CU9,Q96N67,Q9NP73,Q9Y487,Q10713,Q8N3U4,Q9P0J0,Q05086 12 +Sideroblastic anemia 0.2954803551587395 0.1301424344033757 0.8964537377877602 1.0 0.9858510375753804 11 Q9BXW9,Q9NVI1 2 +Abnormality of neuronal migration 0.2039094890493454 0.12982314041584 0.896706354444792 1.0 0.9858510375753804 140 Q16625,Q9NZ01,Q15392,Q9Y487,Q10713,Q9NP72,O75381,O96011,Q9UBB6,Q9BZK7,P51812,Q68CP9,Q9NUQ7,Q6P2C8,O14802,Q96PU5,Q9UEY8,Q71SY5,O43791,P52732,Q15427,Q12824 22 +Neoplasm of fatty tissue 0.3045643491811614 0.1291021975032768 0.8972767832060249 1.0 0.9858510375753804 10 O95140,P27635,Q9BUK6 3 +Decreased specific antibody response to vaccination 0.3383708269605798 0.1273945719852171 0.8986281121664554 1.0 0.9870963501731432 4 P17812 1 +Aplasia hypoplasia of the earlobes 0.3241019703894687 0.123753409482012 0.9015105219934229 1.0 0.9881194077496378 8 O14802,Q8WXE1,P98175 3 +Unusual infection 0.201658490463046 0.1233593126586836 0.9018225747226296 1.0 0.9881194077496378 206 Q9NPL8,Q9H7D7,P61619,Q03519,Q13432,Q9NRW7,Q9NP73,Q9Y487,P06132,Q9BT22,Q9BXW9,Q9H9P8,P78318,Q9H1A4,Q9BZK7,Q9UJW0,P09601,Q9H9B1,Q6PGP7,Q68CP9,Q9NZ08,Q13277,Q13586,Q96J02,Q13423,Q9BQP7,Q9NVR5,O14802,Q03518,Q14739,Q71SY5,P17812,P24468,P28070,O96028,P62263,Q12824 37 +Back pain 0.2346349199986744 0.1233499741692574 0.9018299692854106 1.0 0.9881194077496378 23 P42771,P50402,Q8WXH0,P38398,Q12824,P35670 6 +Spina bifida 0.2247431137011267 0.1231979768589542 0.9019503275983896 1.0 0.9881194077496378 31 Q9BXW9,Q9Y5S9,Q9NVI1,Q9HC21,P38398,Q10713,P21281,Q08J23,Q9Y2W2,O75845 10 +Hyperlordosis 0.215709473800731 0.1209394584493308 0.9037389882123524 1.0 0.9891865000163362 47 Q96DX4,Q99575,Q8WXH0,Q96HY6,Q9NSE4 5 +Abnormality of the menstrual cycle 0.2121696028378451 0.1197899179607771 0.9046495687324992 1.0 0.9892728525107176 51 Q9BUK6,Q9BZK7,Q12824,Q96RR1 4 +Abnormal delivery 0.2386858045989198 0.1196294666401394 0.9047766763410912 1.0 0.9892728525107176 20 O60313,Q9Y487,Q9Y619,O14802 4 +Reticulocytopenia 0.2397540431436067 0.1190296209792647 0.9052518884516064 1.0 0.9892728525107176 19 Q9BXW9 1 +Abnormal shape of the frontal region 0.2134518777863203 0.117902259996789 0.9061451025216578 1.0 0.9894106303313692 103 P13073,Q15392,Q9Y619,Q9Y487,Q9BXW9,P29372,P51812,Q6PGP7,Q68CP9,Q96DX4,O60566,Q6P2C8,Q96J02,O15160,O14802,Q8N3U4,Q14739,P42345,O43791,O96028 20 +Broad long bones 0.2195287794716656 0.1170822268501698 0.9067948937786598 1.0 0.9894980815542904 35 P26196,Q71SY5,O75648,Q6P2C8,Q7LGA3,Q13868,Q6DKJ4,Q08J23 8 +Sprengel anomaly 0.2236195820656339 0.1164519237034708 0.9072943861098424 1.0 0.9894980815542904 28 Q9UM00,Q15427,P46783 3 +Constipation 0.2144500696359756 0.1147826879811837 0.9086173713417 1.0 0.9901459447144338 98 Q71SY5,Q96RR1,Q03164,O43791,P03886,Q13724,Q13423,Q8N3U4,Q05086 9 +Aplasia hypoplasia of the thyroid gland 0.3287939057450666 0.1135993013914277 0.9095554411759066 1.0 0.9902278306001442 5 O15160 1 +Small for gestational age 0.2161820340755862 0.113483317058994 0.9096473886931116 1.0 0.9902278306001442 81 Q9BXW9,Q9H1A4,O75648,Q9BZK7,O60566,Q9Y619,Q9NP73,P46783,P51812,Q8IY17 10 +Eyelid coloboma 0.2938755225138874 0.1123390864847378 0.9105545514019128 1.0 0.9902278306001442 10 Q15427 1 +Neoplasm of the larynx 0.3275307704505573 0.1123297812282228 0.9105619292247896 1.0 0.9902278306001442 4 P42771 1 +Aplasia hypoplasia of the eyelid 0.2636504322274431 0.1102766080326604 0.9121900081886096 1.0 0.9902278306001442 13 O15160,P63241,Q15427 3 +Abnormality of exocrine pancreas physiology 0.2359843619550591 0.1099369621975682 0.9124593686004344 1.0 0.9902829275898344 18 Q9UJW0,P42771,P38398,P09601 4 +Abnormality of the external nose 0.1928753274367315 0.1078934067219613 0.9140802472649564 1.0 0.9909733137346588 224 Q16625,Q15392,Q03164,Q15555,Q9NP73,Q9Y487,Q10713,Q9NP72,Q96J42,O75381,O96011,Q9BZK7,Q13868,P51812,Q9H9B1,P61586,O75845,Q6PGP7,O60566,Q6P2C8,Q96N67,Q96J02,O95831,Q8N3U4,O15228,Q71SY5,O43791,P52732,Q7LGA3,Q9Y5P4,Q12824 31 +Renal insufficiency 0.2130756846159723 0.1067305018689125 0.9150027838201992 1.0 0.991380677040302 76 Q8NFH4,Q9BXW9,Q16625,Q9Y5K6,Q9NZ08,P61619,Q10713,Q8IY17,Q9NQH7,Q9H9B1 10 +Cytochrome c oxidase negative muscle fibers 0.3115451803430621 0.1062478874526871 0.9153856772457588 1.0 0.991558373487156 8 O75648,Q96RR1 2 +Broad finger 0.2147137778002824 0.1059562864477458 0.9156170352386924 1.0 0.991571878946038 34 P26196,O75648,Q6P2C8,Q7LGA3,Q13868,Q6DKJ4,P51812,Q08J23 8 +Hypoplasia of the radius 0.2697953418832802 0.1047517879979557 0.9165727670924776 1.0 0.9921325292542228 12 Q15427,P98175 2 +Abnormal facial shape 0.1720756093072508 0.1036456351879067 0.9174505710171856 1.0 0.9923811196354254 297 Q9NZ01,Q03164,Q15555,Q9NP73,Q9Y487,Q10713,Q9NR45,O75381,Q96AY3,Q9BXW9,O96011,Q9UBB6,Q9UM00,Q9BZK7,Q32P28,P51812,Q9H9B1,P61586,Q05086,Q6PGP7,Q68CP9,Q96DX4,Q9NUQ7,P51571,Q13724,O75648,O60566,Q6P2C8,Q96J02,O15160,Q9BUK6,O95831,P53701,Q8N3U4,P83436,Q96PU5,Q71SY5,O43791,Q7LGA3,Q13555,Q12824 41 +Missing ribs 0.2856735959605261 0.1010166146601488 0.919537271050526 1.0 0.9933981437758412 10 Q14739,Q96T58,O14656,P21281 4 +Abnormality of upper lip 0.1803101083904035 0.1001152446161553 0.9202528326854162 1.0 0.9933981437758412 251 Q16625,Q03164,Q15555,Q9NP73,Q9Y487,O60762,Q9NP72,Q9UM00,Q9BZK7,Q13868,P51812,Q9H9B1,O75845,Q6PGP7,Q68CP9,Q96DX4,P51571,O75648,O60566,Q6P2C8,Q96N67,Q96J02,O15160,Q96F07,Q8N3U4,P83436,Q71SY5,O43791,P52732,Q15427,Q7LGA3,Q13555,Q9Y5P4,Q12824,Q9NSE4 35 +Abnormal morphology of the great vessels 0.1897446083055982 0.1000059301899839 0.9203396174392956 1.0 0.9933981437758412 175 Q15392,O60762,Q9BXW9,Q9UM00,Q9NWM8,P46783,Q9H9B1,Q6PGP7,Q68CP9,Q96DX4,P51571,O75648,O60566,Q6P2C8,Q9NVR5,P53701,Q8N3U4,Q96PU5,Q71SY5,Q15427,Q7LGA3,Q12824 22 +Limb joint contracture 0.2055720184095778 0.0992331086507971 0.9209531876819312 1.0 0.9933981437758412 103 Q99720,Q96AY3,Q15392,Q71SY5,P07196,Q9UP83,Q8WXH0,Q9Y619,Q7LGA3,O14802,O60762,O60313,Q8IZA0 13 +Abnormality of the philtrum 0.1846461373514362 0.0966519945394442 0.9230027640714766 1.0 0.9938100038059428 200 Q16625,Q03164,Q15555,Q9NP73,Q9Y487,O60762,Q9NP72,Q9UM00,Q9BZK7,Q13868,P51812,O75845,Q6PGP7,Q68CP9,O75648,O60566,Q6P2C8,Q96N67,Q96J02,O14802,Q8N3U4,P83436,Q71SY5,O43791,P52732,Q7LGA3,Q13555,Q9Y5P4,Q12824,Q9NSE4 30 +Abnormal clavicle morphology 0.2245272629580449 0.0966094956298086 0.9230365153506084 1.0 0.9938100038059428 21 Q14739,Q96AY3,Q9Y5S9,P48651,Q9Y619,Q6W2J9,O75431,Q8NC56,Q15813 9 +Joint dislocation 0.2098705073165624 0.0964335406071736 0.9231762546938866 1.0 0.9938100038059428 86 Q96PU5,Q9NQT5,P51571,Q8N3U4,Q15427,Q9Y487,P57678,Q9NSE4 8 +11 pairs of ribs 0.3031634741976795 0.0960226574145689 0.9235025776937772 1.0 0.9938100038059428 8 Q14739,Q96T58,O14656,P21281 4 +Abnormality of refraction 0.1845904851424842 0.0947643741147337 0.924501984821678 1.0 0.9938100038059428 145 Q9H7D7,Q15555,P26640,Q9Y487,Q9BXW9,Q9NWM8,Q13868,Q9H582,Q9H9B1,P61586,Q15907,Q05086,Q68CP9,O75648,Q6P2C8,O15160,O14802,P98175,P12235,Q08J23,P49902,Q71SY5,P52732,O43819,Q7LGA3,Q13555,Q12824 27 +Simple ear 0.3129564471326725 0.0944900252700711 0.9247199056759569 1.0 0.9938100038059428 5 Q96KP1,Q92925 2 +Long palpebral fissure 0.2122322521628305 0.0940139681702691 0.9250980608872232 1.0 0.9938100038059428 27 P63000,O43791,Q9NP73,Q6DKJ4,Q13555,P51812 6 +Anosmia 0.3122362869198356 0.0939762705237122 0.9251280066780004 1.0 0.9938100038059428 4 O95140,Q8WWQ0,A6NHR9 3 +Prominent occiput 0.2519570341692805 0.0935243181246952 0.9254870312897177 1.0 0.9938100038059428 13 Q13724 1 +Fatigable weakness of bulbar muscles 0.2612809305348949 0.0933074671757904 0.9256593000172646 1.0 0.9938100038059428 12 Q15165,P35637,Q92804 3 +Capillary hemangioma 0.3067540596872709 0.0932737862681139 0.925686056805737 1.0 0.9938100038059428 7 Q15436,P21281,Q7LGA3 3 +Transient neutropenia 0.3112625770853661 0.0929192360792394 0.9259677236796382 1.0 0.9938100038059428 4 P61011,Q7Z2Z2,Q9H078 3 +Atrioventricular canal defect 0.306367771280055 0.0928530379205108 0.9260203148046102 1.0 0.9938100038059428 7 P36776,Q9UBM7,Q9UHX1,O60826,P24468,P17252 6 +Elliptocytosis 0.2731992212848752 0.0897955539320038 0.9284496813667512 1.0 0.994209716058122 3 P11171,Q8NBF2 2 +Abnormal female reproductive system physiology 0.2034228411242928 0.0896020792444741 0.9286034320571496 1.0 0.994209716058122 62 Q96RR1,Q9H1A4,Q9BZK7,Q9BUK6,Q12824 5 +Long ear 0.2725502920181641 0.0890345811091698 0.9290544274912624 1.0 0.994209716058122 3 P63241,Q7LBC6 2 +Periorbital fullness 0.2211501685778508 0.088663606386748 0.9293492564795678 1.0 0.994209716058122 20 Q7LGA3,Q96N67,Q9NP73 3 +Degeneration of the lateral corticospinal tracts 0.3021303630321115 0.0883810622247894 0.9295738125439754 1.0 0.994209716058122 7 P35637,O00400 2 +Primitive neuroectodermal tumor 0.2332790825999957 0.088250818308622 0.9296773276718078 1.0 0.994209716058122 15 P42771,Q15555,Q14145 3 +Abnormal muscle fiber type distribution 0.2856997011205688 0.0882042418363206 0.929714345962226 1.0 0.994209716058122 9 P51114,P50570 2 +Skin plaque 0.3058441558441631 0.0870593805589331 0.9306243123656576 1.0 0.994209716058122 5 P16615,P22314,P00338,Q92990 4 +Periorbital edema 0.213740283965858 0.086716822151762 0.9308966046451892 1.0 0.994209716058122 23 Q9Y5K6,P28070 2 +Oligodontia 0.2554083243648425 0.0863144963592003 0.9312164150549348 1.0 0.994209716058122 12 O14802,P51812,P61586 3 +Malignant genitourinary tract tumor 0.2191180615048911 0.0857524785726975 0.9316631838624978 1.0 0.994209716058122 20 P61254,P18077,P08708,P62244,P46783,P42766,P43246 7 +External genital hypoplasia 0.1815298023396284 0.0856492790471353 0.9317452233414772 1.0 0.994209716058122 118 Q9BXW9,P51809,Q9UP83,Q15555,Q13724,Q9BZK7,O60566,Q9Y619,O15160,Q10713,O60762,Q8IY17,P53701,Q9NP72,Q9H9B1,O75845 16 +Lumbar hyperlordosis 0.2255006142559306 0.0849281461963918 0.9323185151909276 1.0 0.994209716058122 16 Q96HY6,Q9H553,Q96J02 3 +Abnormal cerebellar vermis morphology 0.2041849361929178 0.0846092495545876 0.9325720453585756 1.0 0.9942460262354312 75 Q8NFH4,Q68CP9,Q12824,Q96B26,Q9UHD1,Q9UM00,O60566,P49959,Q9Y487,Q10713,O14802,Q99653,Q9NP72,Q96J42,Q15907 15 +Embryonal renal neoplasm 0.271305646753195 0.0842339228563146 0.9328704474811572 1.0 0.9942866292835744 10 P51809 1 +Unilateral renal agenesis 0.2243214749336842 0.0834911556917447 0.9334610095753229 1.0 0.9942866292835744 16 Q15427 1 +Perisylvian polymicrogyria 0.3015603773443593 0.0829135460802312 0.9339202829157958 1.0 0.9942866292835744 5 P42345 1 +Hand clenching 0.2801941165921328 0.0825541020479283 0.934206097896876 1.0 0.9942866292835744 9 Q13724,Q00535,Q6W2J9 3 +Glossoptosis 0.2995886252952472 0.0810817124372668 0.9353769691577516 1.0 0.9946468518737264 6 O15160,P98175 2 +Talipes equinovalgus 0.2611940298507376 0.0768542645282007 0.9387394815002374 1.0 0.9946468518737264 3 Q9Y3E5,O75369 2 +Hypoplasia of penis 0.1945824396764382 0.0764584649739972 0.9390543573547828 1.0 0.9946468518737264 97 Q9BXW9,P51809,Q9UP83,Q15555,Q9BZK7,O60566,Q9Y619,Q10713,Q8IY17,P53701,Q9NP72,Q9H9B1,O75845 13 +Brittle hair 0.2367917462406026 0.0764183309633659 0.9390862862483148 1.0 0.9946468518737264 13 Q9Y487 1 +Aplasia hypoplasia of the cerebellar vermis 0.1980459358968995 0.0749207376659232 0.9402777766554338 1.0 0.9946468518737264 68 Q8NFH4,Q68CP9,Q12824,Q96B26,Q9UM00,O60566,Q9Y487,Q10713,O14802,P49959,Q9NP72,Q96J42,Q15907 13 +Periauricular skin pits 0.2603398897097632 0.0738534204889152 0.9411270196423772 1.0 0.9946468518737264 10 O96028,Q9Y2W2,Q8N3U4 3 +Abnormality of the choanae 0.190394765941147 0.0737177164266288 0.9412350014746976 1.0 0.9946468518737264 35 Q9BXW9,P78318,Q9NVI1,P48651,P55011,P38398,P46109,Q96J02,O15160,P42356,O60216,Q9Y2W2 12 +Complete duplication of phalanx of hand 0.2899388483862882 0.0728599379985267 0.9419175740197978 1.0 0.9946468518737264 5 Q9BXW9 1 +Cleft lip 0.1883868692550912 0.0728192480230377 0.9419499539115036 1.0 0.9946468518737264 52 Q9UM00,O43791,Q15427,P46783,O15160,O96028,Q8N3U4 7 +Hyperostosis 0.2504879635653875 0.0726991516670027 0.9420455236363036 1.0 0.9946468518737264 11 P10644,P48651,P22626,P21333,P09651,O00754,P55072,P51812,Q9Y2U8,P19447 10 +Oculogyric crisis 0.2589008568031903 0.0726363661405472 0.9420954871454574 1.0 0.9946468518737264 10 Q05639,P67870,O00429,P61457 4 +Primary peritoneal carcinoma 0.2836210263350917 0.0717886059714218 0.9427701405419786 1.0 0.9946468518737264 7 P49959,P38398,Q92878 3 +Hypoplastic labia majora 0.2401927677126143 0.0713584554032581 0.9431124730671304 1.0 0.9946468518737264 12 Q9UQE7,Q9Y5N6,Q9Y619,O60216 4 +Abnormal labia majora morphology 0.2401927677126143 0.0713584554032581 0.9431124730671304 1.0 0.9946468518737264 12 Q9UQE7,Q9Y5N6,Q9Y619,O60216 4 +Pneumonia 0.1868893299058034 0.0708316416105554 0.9435317486982424 1.0 0.9946468518737264 52 Q13432,Q12824 2 +Limitation of joint mobility 0.1892928260229981 0.0702308714174813 0.944009903144906 1.0 0.9946468518737264 96 Q96AY3,P48735,Q96DX4,O75874,Q8WXH0,Q15427,Q96J02,Q7LGA3,Q9H6K4,Q05086,Q12824 11 +Fetal ultrasound soft marker 0.2205748153673308 0.0700466719268814 0.9441565120131834 1.0 0.9946468518737264 14 O75381 1 +Dry skin 0.1857407921927964 0.0697405778202923 0.9444001439611724 1.0 0.9946468518737264 31 O96011,P52732,Q08J23,P11802,Q6PGP7 5 +Abnormal blood phosphate concentration 0.2832088340370305 0.0679182418709485 0.9458507173699372 1.0 0.9946468518737264 6 P53680,P10644,P51798,Q15813,Q6P1J9 5 +Triangular face 0.1841920738889752 0.0674951382615027 0.9461875323067636 1.0 0.9946468518737264 40 O75381,Q96AY3,O43791,O60566,O14802,Q8N3U4 6 +Decreased circulating level of specific antibody 0.2777100509879211 0.0674326079188126 0.946237310892292 1.0 0.9946468518737264 7 P17812 1 +Abnormality of chorioretinal pigmentation 0.2811626173062339 0.0663343690642761 0.9471116209162352 1.0 0.9946468518737264 4 Q9Y619 1 +Cranial hyperostosis 0.2504065040650365 0.06609452047571 0.947302573340977 1.0 0.9946468518737264 10 P10644,P48651,P22626,P21333,P09651,O00754,P55072,P51812,P19447 9 +Thin upper lip vermilion 0.1820924939913232 0.0657034841398873 0.9476138984671608 1.0 0.9946468518737264 97 Q68CP9,Q03164,P52732,Q9BZK7,Q7LGA3,Q13868,Q9NP73,O14802,P51812,Q8N3U4,Q12824 11 +Stage 5 chronic kidney disease 0.1843622771198228 0.0656984586471467 0.9476178995852548 1.0 0.9946468518737264 27 Q9Y5K6,Q9NQH7 2 +Knee flexion contracture 0.1800208098876727 0.0648625496165641 0.94828343885124 1.0 0.9946468518737264 28 Q96AY3,P49902,P48651,Q7LGA3,Q9H553,O60762 6 +Anteriorly placed anus 0.2220582426054179 0.0641997595659975 0.9488111688402194 1.0 0.9946468518737264 13 P53701,P48651 2 +Abnormal neural tube morphology 0.1775973614123557 0.0639863694622171 0.9489810801593486 1.0 0.9946468518737264 38 Q9BXW9,Q92766,Q9Y5S9,Q9NVI1,Q9HC21,P38398,Q8N3U4,Q10713,P21281,Q08J23,Q9Y2W2,O75845 12 +Autoimmune thrombocytopenia 0.2716049382716048 0.0633739280215603 0.9494687479327876 1.0 0.9946468518737264 7 P40763,P42224,P00491,P50851,P49327,Q9H0U3 6 +Eeg with focal spikes 0.2756493506493562 0.0627282962546841 0.9499828646056124 1.0 0.9946468518737264 5 Q5H8A4,P36776,O75503,P42356 4 +Focal emotional seizure 0.2691355371584478 0.0618537285402412 0.9506793161733268 1.0 0.9946468518737264 7 Q05639,P67870 2 +Upslanted palpebral fissure 0.189704021464584 0.0617964969570214 0.950724893181158 1.0 0.9946468518737264 81 O75381,Q9BXW9,O96011,Q9UM00,Q15555,P52732,O60566,Q7LGA3,Q13868,Q9Y5P4,Q9H9B1,P83436 12 +Leukemia 0.1794773783559437 0.061573553789571 0.9509024379877584 1.0 0.9946468518737264 53 Q9BXW9,P42771,Q9H1A4,P52732,O60566,P08708,Q07812,P46783,Q13492,Q08J23,P43246,P62263 12 +Dysplastic corpus callosum 0.2344251298305224 0.0610363653197462 0.9513302476949268 1.0 0.9946468518737264 11 P49902,Q5JPH6 2 +Autoimmunity 0.1645217387039704 0.0598333868240459 0.952288334361862 1.0 0.9946468518737264 30 Q13586,Q96J02 2 +Colon cancer 0.2021260817905761 0.0597523773318236 0.952352855144829 1.0 0.9946468518737264 15 P42771,P10644,P38398,O60566,O43684,P43246 6 +Localized hirsutism 0.2700421940928311 0.0592309453873905 0.9527681620483436 1.0 0.9946468518737264 4 P27635,P12955,P36551 3 +Abnormality of the thenar eminence 0.1919664511921158 0.0591230568427295 0.952854094057169 1.0 0.9946468518737264 17 P61254,P18077,P08708,P62244,P46783,P42766 6 +Abnormal eyelid physiology 0.2483612778146867 0.0586285682913714 0.9532479556086596 1.0 0.9946468518737264 9 Q96RL7 1 +Narrow nose 0.2669697953881186 0.0579228414826453 0.953810088792596 1.0 0.9946468518737264 6 O75431,P49589,Q07864,Q14683,Q9Y4A5 5 +Obsessive compulsive behavior 0.1633632417558534 0.0576109816087313 0.9540585021444736 1.0 0.9946468518737264 38 Q05086 1 +Long fingers 0.1872937096205388 0.0574202232921184 0.9542104537206556 1.0 0.9946468518737264 75 Q03164,Q15555,Q9NSE4 3 +Ankyloblepharon 0.2368591823491155 0.0573958721338701 0.9542298511436212 1.0 0.9946468518737264 3 P19447,Q6W2J9 2 +Gastrointestinal carcinoma 0.1586186008797893 0.0570549150063394 0.9545014504965814 1.0 0.9946468518737264 28 O60566,Q07812,P08708,P46783,P43246 5 +Abnormality of the inner ear 0.2510089730428257 0.055148868671596 0.95601986378465 1.0 0.9946468518737264 8 Q9Y619 1 +Aplasia hypoplasia of the uterus 0.1887131537367568 0.0548856557623252 0.956229559696091 1.0 0.9946468518737264 16 P53701,O96028,Q16740,O75616 4 +Adenocarcinoma of the colon 0.1861513369359169 0.0548716830345808 0.9562406915444854 1.0 0.9946468518737264 19 P60866,P61254,P18077,P62273,P62913,P62847,P62081,P39019,P28340,P08708,Q07020,P62244,P46777,P46783,Q07864,P42766,P61313 17 +Obsessive compulsive trait 0.2605507854449346 0.0544058496868104 0.9566118183834942 1.0 0.9946468518737264 5 P61981 1 +Eyelid myoclonus 0.2490940589684486 0.0542718328826779 0.9567185905722636 1.0 0.9946468518737264 8 Q05639,P67870,P00374 3 +Neoplasm of the colon 0.1370879967152327 0.0538874612651204 0.9570248266118436 1.0 0.9946468518737264 37 P61254,P42771,Q9UNW1,P18077,P10644,P62847,P38398,O60566,P08708,P62244,O43684,P46783,P42766,P43246 14 +Abnormal mean corpuscular volume 0.1778449850701031 0.0538270148436659 0.9570729859820128 1.0 0.9946468518737264 22 P62081,P08708,Q07020,P61353,Q8NBF2,P62244,P61254,P62273,P39019,P61011,P46783,P42766,P61313,P62913,P62847,Q02241,P46777,Q7Z2Z2,P60866,P18077 20 +Periventricular leukomalacia 0.1831087632501222 0.0524777693153068 0.9581480084390928 1.0 0.9946468518737264 16 Q68CP9,Q93009,Q5JTZ9,O75648 4 +Neoplasm of the large intestine 0.1533823507035745 0.0522943942298926 0.9582941199637214 1.0 0.9946468518737264 43 P42771,P38398,O60566,Q07812,P08708,P62244,P46783,Q14145,P43246 9 +X linked recessive inheritance 0.1639696758577405 0.0522468115867806 0.9583320335905172 1.0 0.9946468518737264 51 P78318,P29372,P51571,Q9NP73,P98175,O95831,Q8N3U4,P38159,O14654 9 +Pancreatic adenocarcinoma 0.2239506536451259 0.0518547604193868 0.9586444217011678 1.0 0.9946468518737264 10 P42771,P38398 2 +Skin pit 0.2059797958288018 0.0514068985374367 0.959001287805454 1.0 0.9946468518737264 12 O96028,Q9Y2W2,Q8N3U4 3 +Triangular shaped phalanges of the hand 0.179440035206595 0.051288155990375 0.959095905834696 1.0 0.9946468518737264 65 Q9BXW9,P26196,Q9Y5S9,Q9NVI1,P38398,O75648,P08708,P62244,Q6W2J9,Q13868,P46783,Q6DKJ4,Q6P2C8,Q15427,Q7LGA3,O60216,Q08J23,P55011 18 +Increased mean corpuscular volume 0.1742767702424963 0.0507047844238205 0.959560764136568 1.0 0.9946468518737264 21 P62081,P08708,Q07020,P61353,P62244,P61254,P62273,P39019,P61011,P46783,P42766,P61313,P62913,P62847,Q02241,P46777,Q7Z2Z2,P60866,P18077 19 +Truncal obesity 0.1769005144150854 0.0502925450947339 0.959889264406376 1.0 0.9946468518737264 16 Q10713 1 +Inguinal hernia 0.1763630870748246 0.0502127410027076 0.9599528585105694 1.0 0.9946468518737264 79 Q71SY5,Q9UM00,Q15555,Q32P28,Q9NWM8,Q9Y487,Q10713,P51812,Q9H9B1 9 +Capillary malformation 0.2018562722257491 0.049991945449644 0.9601288068976876 1.0 0.9946468518737264 12 Q71SY5,P42345 2 +Persistence of hemoglobin f 0.1733717887815841 0.049305358728057 0.9606759490664049 1.0 0.9946468518737264 19 P60866,P61254,P18077,P62273,P62913,P62847,P62081,P39019,P61011,P08708,Q07020,P61353,P62244,P46783,P46777,P42766,P61313 17 +Dental malocclusion 0.1736110866082299 0.0488911567649062 0.961006036315046 1.0 0.9946468518737264 20 P10644,P38398,Q12797,P08754,Q6W2J9,P51812,P21281,P61586 8 +Adenocarcinoma of the intestines 0.1687336814621405 0.0488324531687323 0.9610528191283224 1.0 0.9946468518737264 21 P62081,P08708,Q07020,P61353,P62244,P78549,P61254,P62273,P39019,P46783,Q07864,P42766,P61313,P62913,P62847,P46777,P28340,P60866,P18077,P43246 20 +Synostosis involving bones of the hand 0.1912810342704395 0.0470798327045877 0.9624496006819648 1.0 0.9946546235231072 12 Q9H1A4,Q6DKJ4,P48651 3 +Glaucoma 0.1548689162237506 0.0467369281438256 0.9627228980887416 1.0 0.9946546235231072 83 O75381,O96011,Q15555,O60566,Q13868,P46783,P53701,P61586 8 +Small earlobe 0.2385405202267552 0.0459373421283195 0.9633601908659546 1.0 0.9946546235231072 5 P98175 1 +Selective tooth agenesis 0.2373376623376727 0.0455809476452212 0.9636442549635228 1.0 0.9946546235231072 5 P21281,P21333,P54132,Q6W2J9 4 +Cholestatic liver disease 0.2382343395001669 0.0454135031905433 0.9637777181028536 1.0 0.9946546235231072 4 P54577,Q9H267,Q9UBM7 3 +Pure red cell aplasia 0.1581865622961511 0.0454123229054789 0.9637786588635028 1.0 0.9946546235231072 19 P60866,P61254,P00491,P18077,P62273,P62899,P62913,P62847,P62081,P39019,P08708,Q07020,P61353,P62244,P46783,P46777,P42766,P61313 18 +Ulnar deviation of finger 0.2267706302794021 0.0447984888415511 0.9642679296150044 1.0 0.9946546235231072 7 P28482,Q9UBM7,Q9H2M9,Q15042,Q9Y3E5,P46109 6 +Peripheral cyanosis 0.2226193546174669 0.0438613266565681 0.9650149424726502 1.0 0.9946546235231072 7 P51812 1 +Abnormal localization of kidney 0.1605563700719781 0.0433399680406567 0.9654305312498797 1.0 0.9946546235231072 62 Q68CP9,Q9BXW9,P26196,Q12824,Q9NVI1,P51571,P38398,P08708,P46783,P98175,Q9NP72,O75845 12 +Branchial anomaly 0.2086913647999647 0.0426649953183063 0.965968583836706 1.0 0.9946546235231072 8 P27635,O15160,P46109 3 +Urogenital fistula 0.1977914907437552 0.0390123503606628 0.9688805419465318 1.0 0.9953298926989228 6 P36776,P16435,Q16531,Q9H9Y6,O15160 5 +Vaginal fistula 0.1977914907437552 0.0390123503606628 0.9688805419465318 1.0 0.9953298926989228 6 P36776,P16435,Q16531,Q9H9Y6,O15160 5 +Abnormal heart sound 0.1942932204765464 0.038696379632687 0.9691324598837884 1.0 0.9953298926989228 6 P24468 1 +Branchial fistula 0.197727272727281 0.0383010062936399 0.96944768847021 1.0 0.9953298926989228 5 Q9H9Y6,O15160,P46109,P28482 4 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..4729babf5a3551101e78499013c96033b3fa8bde --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality of von willebrand factor", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Adult onset sensorineural hearing impairment", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonate wasting renal tubular acidosis", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid nasal tip", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Chin with horizontal crease", "Choanal stenosis", "Choking episodes", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clinodactyly of the 2nd finger", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Common atrium", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of renal pelvis", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid apraxia", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Imbalanced hemoglobin synthesis", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Inappropriate sexual behavior", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urinary potassium", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the 5th finger", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist movement", "Lingual dystonia", "Lipemia retinalis", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low self esteem", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Menorrhagia", "Mental deterioration", "Mesomelia", "Metabolic acidosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Percussion myotonia", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Punctate opacification of the cornea", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal sodium wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Sex reversal", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASS", "ABAT", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADSL", "AFG3L2", "AGA", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANXA11", "AP1B1", "AP1S2", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARL6IP1", "ASAH1", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATIC", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7A", "ATP7B", "ATRIP", "ATRX", "ATXN10", "AURKA", "B4GAT1", "BAG3", "BANF1", "BARD1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCKDHA", "BCKDHB", "BCOR", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRCA1", "BRD4", "BUB1B", "BUB3", "BUD23", "C19orf70", "C1QBP", "CAD", "CALR", "CAMK2G", "CANT1", "CAPN1", "CARS", "CARS2", "CASK", "CAST", "CBX2", "CCDC22", "CCDC47", "CCT5", "CD2AP", "CD3EAP", "CDC40", "CDC42", "CDC73", "CDH2", "CDK4", "CDK5", "CDKN2A", "CELF2", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHORDC1", "CHP1", "CHST14", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLCN7", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNP", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COQ9", "COX15", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2A1", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CUL3", "CUL4B", "CUL7", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DBT", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DIAPH1", "DIP2B", "DKC1", "DLAT", "DLD", "DLST", "DNAAF2", "DNAAF5", "DNAJB11", "DNAJB6", "DNAJC13", "DNAJC19", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOLK", "DPF2", "DPM1", "DPP9", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DYNC1H1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EHHADH", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF3F", "EIF4A3", "EIF4G1", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "EPB41", "EPRS", "ERAL1", "ERAP1", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ESCO2", "ESS2", "ETFA", "ETFB", "ETFDH", "EXOC2", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EZR", "FANCD2", "FANCI", "FAR1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD2", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALNT2", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GATC", "GBA", "GCDH", "GCLC", "GDAP1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLS", "GLUD1", "GM2A", "GNAI2", "GNAI3", "GNPAT", "GNS", "GOSR2", "GOT2", "GPAA1", "GPD2", "GPI", "GPT2", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUF1", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HCFC1", "HELLS", "HEXA", "HEXB", "HEXIM1", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-C", "HMGA1", "HMGB3", "HMGCL", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IFT81", "IGBP1", "IGF2BP2", "IGF2R", "IMPAD1", "INTS1", "INTS8", "IRF2BPL", "IRS4", "ISCU", "ITCH", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KIAA0319L", "KIDINS220", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KMT2A", "KMT2B", "L2HGDH", "LAMB1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDLR", "LEMD2", "LEMD3", "LETM1", "LIPA", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPAP1", "LRPPRC", "LRRC8A", "LSS", "MACF1", "MAGED2", "MAGT1", "MAN2B1", "MAPK1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MED12", "MED17", "MED23", "MED25", "MED27", "MESD", "MFN2", "MFSD8", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MOCS1", "MOGS", "MORC2", "MPDU1", "MPG", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MYH9", "MYO6", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEFL", "NEK9", "NELFA", "NEPRO", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP10", "NOP56", "NPC1", "NPC2", "NPM1", "NR2F2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCLN", "OGDH", "OGT", "OPA1", "OPA3", "ORC6", "OXCT1", "P3H1", "P4HB", "PABPN1", "PAFAH1B1", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDHA1", "PDHB", "PDHX", "PDK3", "PEPD", "PEX11B", "PEX14", "PEX19", "PEX3", "PFKM", "PFN1", "PGK1", "PGM1", "PHB", "PHF6", "PHGDH", "PHIP", "PI4KA", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PISD", "PITRM1", "PKN1", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPOX", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKAR1A", "PRKCA", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PTCD3", "PTDSS1", "PTPN1", "PTRH2", "PUF60", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QRSL1", "RAB11B", "RAB18", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RABL3", "RAC1", "RAD21", "RAD50", "RAD51C", "RAI1", "RALA", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RBPJ", "RDH11", "RDX", "REEP2", "REPS1", "RFC1", "RFC2", "RFT1", "RHOA", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNPC3", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS29", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RREB1", "RRP7A", "RSPRY1", "RSRC1", "RTN2", "SAMHD1", "SAR1B", "SARS", "SARS2", "SBDS", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SDHA", "SDHB", "SDHC", "SEC23A", "SEC23B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEPT9", "SERPINB6", "SERPINH1", "SETD2", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC27A4", "SLC2A1", "SLC33A1", "SLC35A3", "SLC37A4", "SLC44A1", "SLC5A6", "SLTM", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPOP", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SRCAP", "SRP54", "SRP72", "SSBP1", "SSR4", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STT3A", "STT3B", "STUB1", "STX3", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCF20", "TCOF1", "TECR", "TELO2", "TERF2IP", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIMM22", "TIMM50", "TIMMDC1", "TKT", "TMCO1", "TMEM126A", "TMEM126B", "TMEM165", "TMEM43", "TMEM70", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOP3A", "TOR1A", "TOR1AIP1", "TP53", "TPI1", "TPM1", "TPM3", "TPP1", "TPP2", "TRAPPC11", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TTC19", "TTC37", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUFM", "TWNK", "TXNDC15", "UBA1", "UBAC2", "UBAP1", "UBE3A", "UBIAD1", "UBR7", "UBTF", "UFC1", "UFD1", "UFSP2", "UMPS", "UNC119", "UNC45A", "UPF3B", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP7", "USP9X", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VMA21", "VPS13A", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WBP11", "WDR1", "WDR26", "WDR36", "WFS1", "WIPI2", "XPNPEP3", "XRCC1", "YARS", "YARS2", "YEATS2", "YIF1B", "YME1L1", "YWHAE", "YWHAG", "ZC3H14", "ZCCHC8", "ZEB2", "ZFR", "ZMPSTE24", "ZNF148", "ZNF644", "ZPR1"], "leading_proteins": ["AARS2", "ABAT", "ABCD3", "ACADM", "ACOX1", "ADAR", "ADD3", "AGL", "AIFM1", "AKT2", "ALDH7A1", "ALG1", "ALG13", "ALG2", "ANAPC1", "ANK3", "ANKFY1", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "ARHGDIA", "ARID2", "ARL3", "ASNA1", "ASNS", "ASPH", "ATAD3A", "ATP2A2", "ATP2C1", "ATP6", "ATP6AP1", "ATP6V0A2", "ATP6V1B2", "ATP7B", "ATRIP", "BANF1", "BAX", "BCOR", "BLM", "BRCA1", "BRD4", "BUB1B", "BUB3", "C19orf70", "CAMK2G", "CARS", "CASK", "CCDC22", "CD2AP", "CDC73", "CDK4", "CDK5", "CDKN2A", "CFL2", "CHD8", "CHORDC1", "CHP1", "CHST14", "CLCN7", "CLN5", "CLPB", "CLPP", "CLTC", "COG2", "COG5", "COG6", "COG7", "COL4A3BP", "COLEC12", "COPA", "COX4I1", "CPOX", "CPT1A", "CRKL", "CSNK2B", "CTBP1", "CTNNB1", "CTPS1", "CYC1", "CYFIP2", "DCPS", "DCTN1", "DCTN4", "DDB1", "DDRGK1", "DDX3X", "DDX6", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DKC1", "DNAAF2", "DNAJC3", "DNM1L", "DNM2", "DOCK7", "DPM1", "DST", "EARS2", "EEF1A2", "EFL1", "EHMT1", "EIF2AK2", "EIF5A", "ELP1", "EMD", 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setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Beta alanine metabolism 2 12 2.6119910202962635 0.0090016618478154 4.415048543689321 11.37135922330097 -0.8604181966405492 0.3092439006787413 2.2758902552526976 0.8450053697120008 1.100689054747258 0.260039693191426 0.0001102658225837 4.557535944516599e-05 0.0003712110430798 0.0052676758380378 0.0341598187242075 +Propanoate metabolism 3 26 2.543970598433903 0.0109600309538144 8.985436893203884 23.429611650485437 -1.655909143338819 0.1878639293264727 4.174562537792417 1.0485296430199056 1.353186679662295 0.2618676004921678 0.0004837416848894 0.0004265388560116 0.0002151657881401 0.0065049624434193 0.062735693833808 +Ascorbate and aldarate metabolism 1 5 2.197250904556859 0.0280025318744923 2.0655339805825244 5.924757281553398 -0.5536813962794395 0.3958378758987996 1.2649404054847184 0.2637825842760801 1.0308101586514495 0.2651468018160532 0.0075297912401724 0.000467906411108 0.0018987369599165 0.0115035556388008 0.0426173940106986 +Histidine metabolism 1 6 2.173147897102941 0.0297691877735968 2.0024271844660193 6.730582524271845 -0.4970121956037042 0.407540563872542 1.2589462121497677 0.9231313586514472 1.0263173146419036 0.2714655739442811 0.0181972414506333 0.0029386578360865 0.0115435449528709 0.0635022977163126 0.2010464765414084 +Cell cycle 17 47 2.15034357148608 0.0315280482844806 13.774271844660197 51.12378640776699 0.0173991045433985 0.7535224495236807 7.363318835662017 6.012262326651711 0.6471200437086846 0.2867365157911225 1.0 0.4299325182794405 0.6796339643303746 0.1540990039001299 0.0576294895773616 +Mismatch repair 2 17 2.0507402538346327 0.0402922486431054 4.83252427184466 18.160194174757283 0.0396129719955681 0.5226528038513648 3.232662558988282 1.5481175418750386 1.0072555486723271 0.3057089512016173 1.0 0.0058373227860703 0.0224191931510111 0.0199432580741765 0.1103031547014423 +Limonene and pinene degradation 1 8 2.0220873028422224 0.0431673335102678 2.8470873786407767 7.543689320388349 -0.6235528363047012 0.370453626645459 1.652716581619816 0.5265144412798544 1.0488730252218026 0.265146659473699 0.0107410366228137 0.0009934566258862 0.0039921150854813 0.0234889728544392 0.0829146757193799 +P53 signaling pathway 8 13 1.9824894048163733 0.0474244920571753 4.75 13.138349514563108 0.2179791659661161 0.5830709418085639 2.6854742308687665 2.7213262747001785 0.8499311192783285 0.3095875853329852 1.0 1.0 1.0 0.1564032996109324 0.1377854368643978 +Fatty acid metabolism 5 31 1.969236055320906 0.0489259903172585 8.45873786407767 28.305825242718445 -0.3147132445585112 0.4274712916424615 4.449364125968959 1.808465811349254 1.2599682225938629 0.3108396196201349 0.0004837416848894 0.0004265388560116 0.0002151657881401 8.804510498081743e-05 0.0006076085796874 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..08633f2ce28d29ab985c7e1a47abfa3ee0edfa24 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 180, + "title": "Average number of proteins per term", + "value": 15.427777777777777 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e1dcfea5bc9f74cc79daaa8586b21885038aaa4e --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d01fbfb334b118ec557ed69bd9168ac094e187f1 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,97 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Primary immunodeficiency 0.8306843983133231 2.7413955565519363 0.0061178807344708 0.6686569039039727 0.1349032454397924 2 Q03518 1 +Beta alanine metabolism 0.8157579013246931 2.6119910202962635 0.0090016618478154 0.8036066782383127 0.146126934811402 12 P11310,P49419 2 +Propanoate metabolism 0.5992472567619089 2.543970598433903 0.0109600309538144 0.8624401555850573 0.146126934811402 26 P30837,P11310,P49419 3 +Ascorbate and aldarate metabolism 0.9097922552837616 2.197250904556859 0.0280025318744923 0.9939782314284829 0.2467412474437615 5 P49419 1 +Pantothenate and coa biosynthesis 0.7132662990593468 2.1831410748303326 0.0290254225403969 0.995017874702291 0.2467412474437615 2 Q9NVE7 1 +Hedgehog signaling pathway 0.7119688614985418 2.176776685220412 0.0294972334213086 0.9954352184834688 0.2467412474437615 2 P48729 1 +Olfactory transduction 0.7119688614985299 2.1767766852203527 0.029497233421313 0.9954352184834726 0.2467412474437615 2 Q13555 1 +Histidine metabolism 0.8992145919014964 2.1731478971029414 0.0297691877735968 0.9956597846292016 0.2467412474437615 6 P49419 1 +Cell cycle 0.459098650954446 2.1503435714860797 0.0315280482844806 0.9968691047008944 0.2467412474437615 47 P42771,P61981,Q9UJX3,Q13616,Q9H1A4,P14635,Q9Y619,P25205,O60566,Q8N3U4,Q13547,Q9UJX4,P24941,Q13416,O14757,P11802,Q9UBD5 17 +Mismatch repair 0.5941527049684171 2.0507402538346327 0.0402922486431054 0.9993904343945385 0.2901041902303591 17 P41440,Q9UQ84 2 +Limonene and pinene degradation 0.8141492218437473 2.0220873028422224 0.0431673335102678 0.9996447951507174 0.290455261953646 8 P49419 1 +P53 signaling pathway 0.6637412968469583 1.9824894048163737 0.0474244920571753 0.9998408179917816 0.3014080944362467 13 P42771,Q13794,P14635,Q07812,O14681,P24941,O14757,P11802 8 +Fatty acid metabolism 0.4982066040952428 1.969236055320906 0.0489259903172585 0.9998801669892994 0.3014080944362467 31 P30837,P11310,P49419,P33121,O15254 5 +Glycerolipid metabolism 0.6432598750987673 1.871154136012967 0.0613237197505518 0.9999887058940166 0.3449459235968541 13 P49419 1 +Ppar signaling pathway 0.5244427126612101 1.6928836231059363 0.0904776211769613 0.999999961415748 0.4390158148411334 19 P50416,P11310,P33121,O15254 4 +Dna replication 0.4673789975265998 1.668986308649982 0.0951200932155789 0.9999999846407492 0.4390158148411334 29 P41440,P25205 2 +N glycan biosynthesis 0.5105548565901913 1.648480780461111 0.0992540514662538 0.9999999932637664 0.4466432315981424 20 O60476,P26572,Q13724,Q96AA3,Q9NP73,Q16706,O60762,Q9BT22 8 +Lysine degradation 0.4437453503131029 1.412036351585847 0.1579392579176346 0.9999999999999636 0.6048737537271113 27 Q15047,P49419 2 +Autoimmune thyroid disease 0.6035042180402367 1.249677432183962 0.2114174045238059 1.0 0.6980858888414 3 P04439,P10321 2 +Allograft rejection 0.6035042180402367 1.249677432183962 0.2114174045238059 1.0 0.6980858888414 3 P04439,P10321 2 +Graft versus host disease 0.6035042180402367 1.249677432183962 0.2114174045238059 1.0 0.6980858888414 3 P04439,P10321 2 +Amyotrophic lateral sclerosis als 0.592195500926946 1.2469168170339135 0.2124279997643352 1.0 0.6980858888414 10 P63000,Q9UHD1,P07196,Q07812,Q99653,P20339,P07197,O96008 8 +Glycolysis gluconeogenesis 0.4095828346718685 1.2443623388444178 0.2133662372208777 1.0 0.6980858888414 31 P49419 1 +Protein export 0.4821311443385768 1.2434272121348853 0.2137104477933484 1.0 0.6980858888414 16 P67812,P61619,P09132,P61009,Q15070,Q9Y5M8 6 +Oxidative phosphorylation 0.3473430273274032 1.2246694638038238 0.2206997838980915 1.0 0.6980858888414 63 O43676,P13073,P09669,O75964,P03886,O95168,O96000,Q9Y487,P00846,Q16718,P56134 11 +Nicotinate and nicotinamide metabolism 0.6684661363019075 1.2237129532254938 0.2210605314664433 1.0 0.6980858888414 6 Q13423,P43490 2 +Tryptophan metabolism 0.4738062894918009 1.1916999024136392 0.2333789363474334 1.0 0.7067415083188622 16 P49419 1 +Valine leucine and isoleucine degradation 0.3844666448406173 1.1887442103002972 0.2345403377347048 1.0 0.7067415083188622 37 P11310,P49419 2 +Regulation of autophagy 0.6614980531509622 1.1861058444675467 0.235580502772954 1.0 0.7067415083188622 5 Q99570,P60520 2 +Riboflavin metabolism 0.6567738978833784 1.1665586108963637 0.2433886661475663 1.0 0.7074421032094893 5 Q9NPH0,Q13614 2 +Proteasome 0.3894954413867141 1.146629037790975 0.2515349700300406 1.0 0.7074421032094893 34 P60900,P28074,O00231,P20618,Q15008,Q99436,P28070,P28072,P49721,Q9UL46,Q92530,P51665,P25787,O43242,P25788 15 +Parkinsons disease 0.337516226712852 1.0779322755720364 0.28106398055039 1.0 0.7550972611801524 58 O43676,P13073,P09669,P03886,O95168,O96000,P00846,Q16718 8 +Pyruvate metabolism 0.3883477096653909 0.9875154949452872 0.3233899905982014 1.0 0.8315742615382321 27 P49419 1 +Arginine and proline metabolism 0.4100398725976974 0.9605534013215008 0.336776768297129 1.0 0.849993036417834 20 P49419 1 +Steroid hormone biosynthesis 0.604951734448392 0.9487943931053926 0.3427251941108356 1.0 0.849993036417834 4 Q53GQ0 1 +Rna polymerase 0.4924716500886118 0.9356729894760712 0.3494415816384428 1.0 0.849993036417834 12 P19387,O15160,O14802,O15514 4 +Tgf beta signaling pathway 0.591326255676035 0.9045182531987868 0.3657206599911267 1.0 0.8588579874447478 6 P61586,Q13616 2 +Cytosolic dna sensing pathway 0.5669743249960709 0.80658260333429 0.41990699985688 1.0 0.9477490128408336 6 O15160 1 +Antigen processing and presentation 0.3985322944454885 0.8043033845460494 0.4212217834848148 1.0 0.9477490128408336 17 P54652,Q03519,Q9UL46,Q03518 4 +Vibrio cholerae infection 0.3832656687452174 0.7851325011591336 0.4323758856659572 1.0 0.9608353014799048 20 Q9Y5K8,P61619,O43731,Q9Y487,P24390,P17252,P55011,Q93050 8 +Ubiquitin mediated proteolysis 0.3213006182136626 0.7543185763345406 0.4506579504817205 1.0 0.9773304950205988 45 Q96PU5,O95071,Q9UJX3,P29372,Q9H1A4,Q13616,P38398,Q96J02,Q9UJX4,Q16763,Q14145,Q9C0C9,Q9Y385,Q15369,Q05086 15 +Oocyte meiosis 0.3310701182839632 0.7134589712648749 0.4755617929579179 1.0 0.9988830516262616 36 P61981,Q9UJX3,Q9UHD1,P30154,Q9H1A4,Q13616,P14635,Q13555,Q9UJX4,P51812,Q99653 11 +Snare interactions in vesicular transport 0.4041834969190191 0.7107420052840572 0.4772441246658805 1.0 0.9988830516262616 15 O43752,O14653,O95249,P51809 4 +Nod like receptor signaling pathway 0.5265469294892758 0.6936629046826944 0.4878936345564593 1.0 1.0 7 Q96RT1 1 +Butanoate metabolism 0.3595653096718588 0.6559917594737922 0.5118294263439598 1.0 1.0 21 P49419 1 +Nucleotide excision repair 0.3593350260258554 0.6545673832343825 0.5127463298244164 1.0 1.0 21 P41440 1 +Glutathione metabolism 0.3569189418200639 0.6396828624456578 0.5223787992104267 1.0 1.0 21 P48735,P28161,O75874,P00390,P10620,P78417 6 +Adipocytokine signaling pathway 0.387521081402531 0.6210281466405237 0.534581103989439 1.0 1.0 15 P42345,P33121,P31751,P50416,P54619,Q9UKU0,O14654 7 +Wnt signaling pathway 0.3384300504521532 0.6157416706256924 0.5380650300796272 1.0 1.0 26 Q9HB71,P63000,Q9UHD1,P30154,Q13616,Q99653,Q9BZK7,Q13555,Q9HCK8,P17252,P48729,P61586 12 +Endocytosis 0.3065877815927944 0.5786507219298296 0.562824872656541 1.0 1.0 41 Q96PU5,P63010,P04439,P50570,P54652,O95782,Q9NRW7,Q9Y371,Q96J02,Q6WKZ4,Q9BRG1,Q15907 12 +Long term depression 0.4485026484343452 0.5729206924333508 0.5666983933019898 1.0 1.0 10 P63096,Q14344,P30154,P07948,P08754,P04899,P17252 7 +T cell receptor signaling pathway 0.432605272212711 0.5676853093004938 0.5702486685984838 1.0 1.0 11 Q99653,P61586,P11802,P31751 4 +Calcium signaling pathway 0.3718857542301729 0.5405182443113388 0.5888396825168705 1.0 1.0 15 Q9UHD1,Q99653,P20020,Q13555,P12235 5 +Fructose and mannose metabolism 0.405344713161179 0.5131259772307243 0.6078632012660399 1.0 1.0 12 P34949 1 +Progesterone mediated oocyte maturation 0.3241723174589902 0.4837650320929288 0.6285526342554353 1.0 1.0 23 P63096,Q9UJX2,Q9UJX3,P31751,Q9H1A4,P08754,P14635,Q9UJX4,P51812,P24941,P17252 11 +Tight junction 0.2960862037997552 0.4799556740346776 0.6312589120127989 1.0 1.0 38 Q16625,P31751,P30154,P16989,Q9Y2J2,P55196,P61586,P11802 8 +Valine leucine and isoleucine biosynthesis 0.4260584330168422 0.4192281707925857 0.6750493858382427 1.0 1.0 9 P26640,Q9P2J5,Q9NSE4 3 +Mtor signaling pathway 0.3788661647609165 0.4027459019389887 0.6871351622270394 1.0 1.0 12 P42345,P31751,Q13131,P51812,P23588 5 +Chronic myeloid leukemia 0.364123897018648 0.3991122428170024 0.6898105017272274 1.0 1.0 13 P42771,P62993,P31751,Q13547,P11802,P46109 6 +Glioma 0.3909066818863324 0.3972533092112296 0.6911806743826028 1.0 1.0 11 P42771,P62993,P42345,P31751,Q13555,P11802 6 +Porphyrin and chlorophyll metabolism 0.3761506690920412 0.3921105788622075 0.6949765113575752 1.0 1.0 12 P09601,P06132,P30519 3 +Drug metabolism cytochrome p450 0.4178889215374373 0.3905566382349572 0.6961249824929467 1.0 1.0 9 P10620,P78417 2 +Purine metabolism 0.2630416047510416 0.3786543328168985 0.7049445694796088 1.0 1.0 52 P49902,O75414,P49005,O15514,Q9NR33,O15160,O14802,O43252,P19387,Q9BW91,P30520 11 +Biosynthesis of unsaturated fatty acids 0.3705394579613433 0.3705760828255277 0.7109532987885954 1.0 1.0 12 Q53GQ0 1 +Natural killer cell mediated cytotoxicity 0.3682204040233817 0.3618545737597312 0.7174607076372315 1.0 1.0 12 P04439,P62993,P63000,Q9UHD1,Q99653,P17252 6 +Citrate cycle tca cycle 0.2959577575860007 0.3574479626709898 0.7207564760912966 1.0 1.0 25 O75874,Q9P2R7,P48735 3 +Regulation of actin cytoskeleton 0.2731456980167234 0.3549366062309261 0.7226370837883005 1.0 1.0 42 Q14344,Q8TBX8,P63000,Q9UQB8,Q96F07,Q13576,P61586,Q7L576,O15145 9 +Metabolism of xenobiotics by cytochrome p450 0.3847937275020675 0.3306127588947413 0.7409370075064028 1.0 1.0 10 P10620,P78417 2 +Neurotrophin signaling pathway 0.2894300741866769 0.3192378651385366 0.7495461457093335 1.0 1.0 24 P61981,P62993,P31751,P63000,Q07812,Q13555,P51812,P41240,P61586,O14654 10 +Rig i like receptor signaling pathway 0.4274845791990773 0.3178000875323986 0.7506365843012082 1.0 1.0 5 Q13546,Q14258,O00571 3 +B cell receptor signaling pathway 0.391801322539749 0.3057940367300908 0.7597614691261174 1.0 1.0 9 Q99653,P63000,P31751,Q9UHD1 4 +Fc gamma r mediated phagocytosis 0.2903604047839258 0.2981223933736218 0.7656097507991746 1.0 1.0 22 P49006,P63000,P50570,P31751,P29966,O00429,P17252,O15145 8 +Bladder cancer 0.4123079737774383 0.277335760204744 0.7815223033701939 1.0 1.0 4 P11802 1 +Basal transcription factors 0.4082979574609623 0.2670332752423777 0.7894435410888905 1.0 1.0 6 P35269 1 +Huntingtons disease 0.244443010958324 0.2440539075584042 0.8071890696962158 1.0 1.0 78 O43676,P13073,O95182,P09669,P62487,Q9UJW0,O95782,O95168,Q07812,O15514,O96000,P19387,Q13547,P08574,P63010,P00846,P12235,Q16718 18 +Gap junction 0.3299267564674906 0.2344326400444041 0.8146491214617759 1.0 1.0 12 P63096,Q9BUF5,P62993,P08754,P04899,P07437,P17252 7 +Melanogenesis 0.3780200293744974 0.2304611665950681 0.8177334359234036 1.0 1.0 8 P63096,P08754,Q13555,P17252 4 +Pyrimidine metabolism 0.2458702730331713 0.2250284193093561 0.821957165770917 1.0 1.0 45 P04183,P49902,P62487,P31350,O75414,P62875,Q9NRF8,P17812,P49005,O15514,Q9NR33,O15160,O14802,P56282,Q16881,P19387 16 +Long term potentiation 0.3306621256884953 0.1800040643760274 0.8571493774082657 1.0 1.0 10 Q99653,Q13555,P51812 3 +Base excision repair 0.2651957423922491 0.1778698448895073 0.8588251934680984 1.0 1.0 18 P18887,P49005,Q9NR33 3 +Rna degradation 0.2419031078046111 0.1753134872537995 0.8608333145948432 1.0 1.0 34 Q9Y4Y9,Q96B26,Q9NQT5,Q13868,P62312 5 +Non homologous end joining 0.3645071088852404 0.1702925721388297 0.8647800525188527 1.0 1.0 6 P49959,Q92878 2 +Prion diseases 0.3601609273391711 0.1625075383585725 0.8709061924310504 1.0 1.0 5 Q07812 1 +Erbb signaling pathway 0.2999582873367557 0.1587656799240099 0.8738534892407397 1.0 1.0 12 P62993,P42345,P31751,Q13555,P17252 5 +Ether lipid metabolism 0.3505673307910137 0.1457373140001156 0.8841287635237747 1.0 1.0 6 Q15102,Q7L5N7 2 +Alzheimers disease 0.22165001102721 0.1457247864346683 0.8841386534959279 1.0 1.0 59 O43676,P13073,P09669,O95168,O96000,P00846,Q16718 7 +Pathogenic escherichia coli infection 0.2458288201478044 0.131973316137088 0.8950053977497676 1.0 1.0 19 Q16625 1 +Non small cell lung cancer 0.2945970555593935 0.0983972903551119 0.921616826223738 1.0 1.0 9 P42771,P11802,P62993,P31751 4 +Drug metabolism other enzymes 0.3130886651510303 0.0945403789218683 0.9246799083248208 1.0 1.0 6 P04183,P12268,P49915,P00492,P11172 5 +Prostate cancer 0.2710606584507911 0.0939828077780574 0.9251228136870466 1.0 1.0 11 P24941,P42345,P31751 3 +Chemokine signaling pathway 0.2053089213982536 0.0692914372885893 0.94475764141084 1.0 1.0 20 P63096,P62993,P31751,P63000,P07948,P08754,P41240,P17252,P61586,P46109 10 +Fc epsilon ri signaling pathway 0.2649507039579665 0.0626917842594183 0.9500119397369836 1.0 1.0 8 P17252,P62993,P63000,P31751 4 +Epithelial cell signaling in helicobacter pylori infection 0.1793900048755687 0.0521426153785795 0.958415056969438 1.0 1.0 18 Q9Y5K8,Q9Y487,P63000,Q93050 4 +Gnrh signaling pathway 0.2522728008935571 0.0511333707648615 0.9592192447394212 1.0 1.0 6 Q13555,P62993 2 +Vascular smooth muscle contraction 0.2219959259401068 0.0478438175583301 0.961840715158951 1.0 1.0 9 P61586 1 +Toll like receptor signaling pathway 0.2342975446169255 0.0467734881556143 0.9626937592866384 1.0 1.0 7 P31751 1 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..186d3cb4ce3176d49e1b92d549cd8e69fedf53f2 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTN1", "ACTN4", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGA", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALYREF", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEX1", "APRT", "AQR", "ARF6", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AURKA", "B4GAT1", "BAIAP2", "BAX", "BCAS2", "BCAT2", "BCKDHA", "BCKDHB", "BIRC6", "BLM", "BLVRA", "BNIP1", "BRCA1", "BUB1B", "BUB3", "BUD23", "BUD31", "CAB39", "CACYBP", "CAD", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CAPN2", "CARS", "CARS2", "CASK", "CBR1", "CCDC6", "CCNB1", "CD47", "CDC16", "CDC23", "CDC27", "CDC34", "CDC40", "CDC42", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDKN2A", "CETN2", "CFL1", "CFL2", "CHD8", "CHDH", "CHEK1", "CHERP", "CHMP2A", "CHMP6", "CHORDC1", "CHP1", "CHST14", "CKB", "CKMT1A*", "CLN5", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT9", "COMT", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPOX", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CS", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CXADR", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DBT", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DECR2", "DERL1", "DFFA", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIS3", "DLAT", "DLD", "DLST", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DPM1", "DPYSL2", "DPYSL5", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", 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0.4700160656917811 10.715952071828754 9.89080826726751 1.1018591616314604 0.3542822656143392 0.020546427317602 0.003227293397994 0.0163248196578674 0.0722234751014844 0.028600952739884 +Uch proteinases 6 44 2.3439771922204367 0.0190793380858831 12.934466019417476 45.69174757281554 0.4676332859413379 0.5268776688735902 7.345038379241775 2.489712786954197 1.2496925486564852 0.3629400025319104 0.082041919335586 0.3175327074700926 0.0413282647695778 0.1272831365513204 0.0911771595282935 +Intra golgi traffic 7 16 2.337484869732919 0.0194139867561276 4.424757281553398 13.87135922330097 0.7636302424906817 0.4243971711811651 2.688824171738392 3.845367291797066 0.9598354803720488 0.3140361333882177 1.0 0.1835089509173778 0.0625314301217693 6.504543740614521e-06 0.0001571171958764 +Mitotic g1 phase and g1 s transition 32 76 2.313977650938155 0.0206689480958632 22.104368932038835 76.02184466019418 0.5927262006732629 0.5705780900762646 11.678595487596883 5.354610434747646 1.3736272695770486 0.3846948779804449 1.0 0.5002968122729333 0.1619396552785848 0.2711693838539959 0.0042598689369938 +Orc1 removal from chromatin 13 49 2.293060490522312 0.0218445226232733 14.364077669902912 49.74757281553398 0.6917566411101944 0.5422658696614091 8.355189705990739 2.308567607855075 1.2721915859610031 0.3803308697876651 1.0 0.2695684389372801 0.0251363642152908 0.0740730415771438 0.0135076229880657 +Cristae formation 3 20 2.1866752934353166 0.0287662364670899 8.475728155339805 19.805825242718445 0.8613288847471563 0.2756396593916832 3.7825471979528897 1.2052333490949263 1.5890526548766304 0.3070386069824295 0.028760355210038 0.0073558029266518 0.0279813079733609 0.0039153945652928 0.0090813539263591 +Cytoprotection by hmox1 14 65 2.157236222638617 0.0309872634601782 15.264563106796116 64.83495145631068 0.939000341067099 0.4699320360831873 6.884300879212943 3.5957015529431366 1.0482386655891682 0.3835416044430508 1.0 0.4130249240673272 0.0220749431150344 0.0014529499519404 0.0002870293650316 +Organelle biogenesis and maintenance 27 87 2.109498639689113 0.03490156331145 25.364077669902912 93.59466019417476 0.8635708484684039 0.4952956395971041 8.486338013959335 9.495950625534562 1.0729913690397648 0.3929655478972317 0.2540871741576797 0.0392662733512417 0.1192492078479772 0.1209646142241785 0.1646759641409868 +Runx1 regulates transcription of genes involved in differentiation of hscs 6 39 2.050312607805452 0.0403339350527884 11.74514563106796 40.9247572815534 0.4838158037368226 0.5501011058260618 6.5789160679611225 1.5190277579548277 1.1933646193238052 0.3604187581137549 0.0709977095462976 0.2801168002074996 0.028249351231176 0.0843199651347959 0.0477436223700896 +S phase 28 94 2.0240742535902885 0.0429625122508161 25.58252427184466 94.497572815534 0.3936025929765626 0.6471527110395977 12.311904628033766 6.6662819095148595 1.1799446716032989 0.3778079902664983 1.0 0.1757629685498992 0.0675797720929864 0.0153693435551289 0.0002531538962007 +Dna strand elongation 4 25 2.020502017602279 0.0433313410746383 8.29126213592233 27.77912621359223 -0.0601217410983142 0.6295538041103502 4.847441659269622 2.424040439438107 0.8611698692996907 0.3086752803551498 1.0 0.0121686135974036 0.045127039841821 0.0530915597366878 0.0265417931189519 +Pkmts methylate histone lysines 2 17 1.980406428389192 0.047657878207123 4.837378640776699 14.12864077669903 -0.3790466366518857 0.4287134426211142 3.2042539871103717 3.75660649087302 1.1177819871791863 0.2979041388027998 0.048546111259079 0.001369405333307 0.0099655953739765 0.1016707597438449 0.0237058173966905 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a60232373f58f896ca07cd1c321962c2c9eb8254 --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 1364, + "title": "Average number of proteins per term", + "value": 18.89222873900293 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..516f9cb5ac01486d0b2e3a342c638c3c87f0be26 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..67220827103a279577b2242f788448b65ef1f1d7 --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,536 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Long term potentiation 0.8803113850145935 2.9668591761810417 0.003008587245679 0.983590561675999 0.0446055761207205 2 P07196 1 +Ras activation upon ca2 influx through nmda receptor 0.8803113850145935 2.9668591761810417 0.003008587245679 0.983590561675999 0.0446055761207205 2 P07196 1 +Negative regulation of nmda receptor mediated neuronal transmission 0.8803113850145935 2.9668591761810417 0.003008587245679 0.983590561675999 0.0446055761207205 2 P07196 1 +Unblocking of nmda receptors glutamate binding and activation 0.8803113850145935 2.9668591761810417 0.003008587245679 0.983590561675999 0.0446055761207205 2 P07196 1 +N glycan trimming and elongation in the cis golgi 0.8543626337982413 2.849730420144399 0.0043756298525301 0.997474850474018 0.0455599932736727 2 O60476 1 +Transport and synthesis of paps 0.852092118066814 2.839402720234567 0.0045198074064627 0.9979274836286998 0.0467046765334483 2 O43252 1 +Constitutive signaling by akt1 e17k in cancer 0.8430100551410946 2.797963771308358 0.0051425880465492 0.9991173558917292 0.0523469410111427 2 P31751 1 +Choline catabolism 0.953026409289732 2.78003285062069 0.0054353399715441 0.99940919544676 0.0549170646013789 3 P49419 1 +Mitochondrial biogenesis 0.5758189765261678 2.7547163339910465 0.0058743040895528 0.9996764566436386 0.0584857721032848 35 P48735,O75964,Q96RR1,Q13505,Q86X55,Q9BUR5,Q9BZK7,O00411,P00846,P56134 10 +Regulation of lipid metabolism by pparalpha 0.6283375620269342 2.706142430020107 0.0068069844066074 0.9999100693162096 0.0602904333156658 25 P11310,Q71SY5,P33121,O75376,P50416,Q86X55,Q9BZK7,Q6P2C8,O60244 9 +Runx3 regulates p14 arf 0.8027894907557571 2.611957935094395 0.0090025330244047 0.9999956050839712 0.0777479872381983 2 P25440 1 +Ptk6 regulates cell cycle 0.7963023029516642 2.5815728215893428 0.0098351239419351 0.9999986034622906 0.0817994454682903 2 P11802 1 +Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.7963023029516642 2.5815728215893428 0.0098351239419351 0.9999986034622906 0.0817994454682903 2 P11802 1 +Camk iv mediated phosphorylation of creb 0.790139474537782 2.5526074357488016 0.0106919928876054 0.9999995712551678 0.0868087993969873 2 Q13555 1 +Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.790139474537782 2.5526074357488016 0.0106919928876054 0.9999995712551678 0.0868087993969873 2 Q13555 1 +Amino acid transport across the plasma membrane 0.8902819186886503 2.521560606412413 0.0116835546969653 0.9999998908122404 0.0915883253256365 3 Q15758 1 +Activated ntrk2 signals through cdk5 0.7807330522218635 2.508209793994828 0.0121344598095995 0.999999941406624 0.0945794467445362 2 Q00535 1 +Nuclear receptor transcription pathway 0.7784625364904253 2.4974591726845774 0.0125086868227346 0.9999999650538592 0.09639462613678 2 O75376 1 +The activation of arylsulfatases 0.7722997080765373 2.4682123142542323 0.0135789752786394 0.9999999920383168 0.0997382018951376 2 Q8NBJ7 1 +Loss of mecp2 binding ability to the ncor smrt complex 0.8660472303762161 2.419638049452581 0.0155359624354831 0.9999999994696 0.1086720654461489 3 Q9BZK7 1 +Chromatin modifying enzymes 0.438592691434871 2.3893851811747675 0.0168765981629104 0.999999999917328 0.1122911214351698 74 Q8NB78,Q9H7B4,Q9UBU8,Q03164,O75376,Q86X55,Q96ES7,Q9BZK7,Q96KQ7,Q15047,Q13547,Q9Y2K7,Q9H9B1,P11802,Q12824 15 +Uch proteinases 0.4906904519620902 2.3439771922204367 0.0190793380858831 0.999999999996122 0.1204824868015953 44 Q8NB78,P28074,P85037,P20618,P49721,P28070 6 +Intra golgi traffic 0.6609156955501433 2.337484869732919 0.0194139867561276 0.9999999999975652 0.1220307738956592 16 O60476,Q9UP83,Q14746,O14653,O95249,Q9NRW7,O43752 7 +Mitotic g1 phase and g1 s transition 0.4319708150850936 2.313977650938155 0.0206689480958632 0.9999999999995756 0.1275676253518439 76 P60900,Q14181,P49736,Q9Y619,P25205,Q15008,Q13547,Q9Y5N6,Q9UL46,Q9UBD5,P31751,P00374,P31350,P30154,P33993,Q99436,Q5TKA1,P49721,P11802,P04183,P28074,P14635,P56282,P25787,Q13416,P42771,Q13616,O00231,P20618,Q9NR33,P24941,P28070 32 +Gab1 signalosome 0.7392150502757064 2.309539742841796 0.0209136489524361 0.999999999999698 0.1279202563727691 2 P41240 1 +Signal regulatory protein family interactions 0.739215050275694 2.3095397428417357 0.0209136489524395 0.999999999999698 0.1279202563727691 2 Q08722 1 +Orc1 removal from chromatin 0.4662746199009693 2.2930604905223113 0.0218445226232733 0.9999999999999176 0.1318403931776317 49 P28074,Q13616,O00231,Q13416,Q9Y619,P25205,P20618,Q99436,P28070,P24941,P49721,Q9UL46,Q9UBD5 13 +Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.8279520483387203 2.2570657330536585 0.0240039676899201 0.999999999999996 0.1393251571448984 3 P61009 1 +Synthesis secretion and deacylation of ghrelin 0.8279520483387203 2.2570657330536585 0.0240039676899201 0.999999999999996 0.1393251571448984 3 P61009 1 +Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.821792769898488 2.2305121518759163 0.0257134616299072 0.9999999999999996 0.1467496303899311 3 Q5TKA1 1 +P75ntr regulates axonogenesis 0.8170527592871771 2.210026804552124 0.027103302061685 1.0 0.1533979419590808 3 P61586 1 +Cristae formation 0.5902463033081078 2.1866752934353166 0.0287662364670899 1.0 0.1614697388523075 20 P00846,Q13505,O75964 3 +Egfr transactivation by gastrin 0.7119688614985415 2.176776685220412 0.0294972334213086 1.0 0.1628916048043323 2 P62993 1 +Shc1 events in erbb2 signaling 0.7119688614985415 2.176776685220412 0.0294972334213086 1.0 0.1628916048043323 2 P62993 1 +Acetylcholine regulates insulin secretion 0.7119688614985313 2.1767766852203616 0.0294972334213123 1.0 0.1628916048043323 2 P29966 1 +Cytoprotection by hmox1 0.4258713280517941 2.157236222638617 0.0309872634601782 1.0 0.1694452771947386 65 P13073,P09669,P28074,Q13616,O75376,O43819,Q86X55,Q9BZK7,P20618,P28070,Q14145,P49721,P09601,P30519 14 +The nlrp3 inflammasome 0.8031713983977095 2.1497838072956705 0.0315723196179211 1.0 0.1694452771947386 3 P09601 1 +Inflammasomes 0.8031713983977095 2.1497838072956705 0.0315723196179211 1.0 0.1694452771947386 3 P09601 1 +Purinergic signaling in leishmaniasis infection 0.8031713983977095 2.1497838072956705 0.0315723196179211 1.0 0.1694452771947386 3 P09601 1 +Organelle biogenesis and maintenance 0.4112533426237101 2.109498639689113 0.03490156331145 1.0 0.1830870724281874 87 Q96RR1,Q13505,O75376,Q86X55,Q10713,P00846,O75935,Q92538,P48735,A0AVF1,Q9BZK7,Q15648,Q9BUR5,O00411,Q9H6D7,Q15691,O00471,Q92973,A6NIH7,P61981,O75964,Q5XKP0,Q68CZ6,P36542,P54619,Q9NX63,P56134 27 +Rora activates gene expression 0.8812471425686192 2.069428958772206 0.0385058513802456 1.0 0.1923882098265753 4 P50416,Q9BZK7 2 +Runx1 regulates transcription of genes involved in differentiation of hscs 0.4757953175130278 2.050312607805452 0.0403339350527884 1.0 0.1983719575752483 39 P28074,Q03164,P20618,Q96J02,P49721,P28070 6 +S phase 0.399851245979057 2.0240742535902885 0.0429625122508161 1.0 0.208544009644531 94 Q9Y619,P25205,Q9BRX5,Q9UL46,P41440,Q9UBD5,Q9UJX3,P31751,Q9H1A4,Q99436,Q5TKA1,P49721,P11802,P28074,Q9UJX4,Q9BRT9,P28070,Q13416,Q16763,Q8N3U4,P40938,Q13616,P20618,P49005,Q9NR33,Q96FF9,P24941,O00231 28 +Dna strand elongation 0.532574945132208 2.020502017602279 0.0433313410746383 1.0 0.2090056142847454 25 P49005,P41440,Q9BRT9,P25205 4 +Smad2 smad3 smad4 heterotrimer regulates transcription 0.7686270138216912 1.9982780401644693 0.0456865249059039 1.0 0.2172375082064517 3 P50750 1 +Pkmts methylate histone lysines 0.582961361680159 1.980406428389192 0.047657878207123 1.0 0.2188732184327134 17 Q03164,Q15047 2 +Ngf stimulated transcription 0.7621866097695438 1.9697880173121547 0.0488626704561974 1.0 0.2216336755863123 3 P50570 1 +Grb2 sos provides linkage to mapk signaling for integrins 0.6694777813817689 1.966068180789972 0.0492907353489906 1.0 0.2216336755863123 2 P62993 1 +Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.6694777813817667 1.9660681807899605 0.0492907353489919 1.0 0.2216336755863123 2 P63000 1 +Class i mhc mediated antigen processing presentation 0.3818346374896297 1.9121728823182995 0.0558540231115025 1.0 0.2408491416692529 104 P61619,Q03519,P52888,Q9C0C9,Q9UL46,Q9UJX3,Q9H1A4,Q99436,O75396,P49721,Q9Y385,Q05086,P04439,Q9NZ08,P28074,P55786,Q96J02,Q14145,Q16763,Q03518,Q96PU5,Q13616,P20618,P28070,Q5T4S7,O94979 26 +Antigen processing ubiquitination proteasome degradation 0.397544038970856 1.9086822318409649 0.0563030966459694 1.0 0.2408491416692529 82 Q96PU5,Q9UJX3,P28074,Q9H1A4,P55786,Q13616,P20618,Q96J02,P28070,P52888,Q14145,P49721,Q16763,Q5T4S7,Q9C0C9,Q05086 16 +Transcriptional regulation of white adipocyte differentiation 0.5637325106388482 1.9037586813670224 0.0569416200204295 1.0 0.2408491416692529 18 Q71SY5,O75376,Q86X55,Q9BZK7,Q6P2C8,Q9Y2X0,P11802,O60244 8 +Inositol phosphate metabolism 0.6565034057735863 1.9008811372068048 0.05731758331562 1.0 0.2408491416692529 2 Q9BW91 1 +Transcriptional activation of mitochondrial biogenesis 0.6218421619073699 1.9001227552222923 0.0574170121426744 1.0 0.2408491416692529 14 P48735,Q96RR1,Q86X55,Q9BZK7,O00411 5 +Carnitine metabolism 0.8306073834364813 1.897049000759354 0.057821471214861 1.0 0.2411880328350778 6 O43772 1 +Metabolism of fat soluble vitamins 0.8309568240831737 1.883465974280159 0.0596372468127948 1.0 0.2450156766646148 5 Q9Y5Z9 1 +Cyclin a cdk2 associated events at s phase entry 0.4479679498158684 1.875744621048029 0.0606903556002556 1.0 0.2485935286448908 42 P31751,P28074,Q13616,P20618,Q99436,P49721,P28070,Q5TKA1,Q9UL46,P24941,P11802 11 +Flt3 signaling 0.739454899415965 1.8686475843701913 0.0616718608749553 1.0 0.24874596672296 3 P31751,P41240 2 +Signaling by ntrk2 trkb 0.7394548994159627 1.8686475843701833 0.0616718608749564 1.0 0.24874596672296 3 P63000,Q00535 2 +Signaling by ntrk3 trkc 0.7394548994159553 1.8686475843701496 0.0616718608749611 1.0 0.24874596672296 3 Q8WX92,Q07812 2 +Formation of atp by chemiosmotic coupling 0.718712414710551 1.8661211731912344 0.0620244142989117 1.0 0.24874596672296 10 P00846,O75964 2 +Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.8230372294472912 1.8514551625354767 0.0641040995062953 1.0 0.2519826850910284 5 Q8NB78 1 +Synthesis of dna 0.3919137122095896 1.8346940306449837 0.0665510372640105 1.0 0.2564282904748882 81 Q9Y619,P25205,Q9BRX5,Q9UL46,P41440,Q9UBD5,Q9UJX3,Q9H1A4,Q99436,P49721,P28074,Q9UJX4,Q9BRT9,P28070,Q13416,Q16763,P40938,Q13616,P20618,P49005,Q9NR33,P24941,O00231 23 +Transcriptional regulation by runx2 0.4234901595185845 1.8260132908699491 0.0678482598638436 1.0 0.2599579394783224 48 P31751,P28074,Q13616,P14635,P20618,P28070,P49721,Q9UL46,P11802 9 +Bmal1 clock npas2 activates circadian gene expression 0.8165714061968403 1.8122695573890268 0.0699445559835287 1.0 0.267239143869841 4 Q86X55,Q9BZK7 2 +Cellular response to chemical stress 0.3894190120092254 1.7949856871233862 0.07265598037683 1.0 0.2730103505068766 76 P13073,P09669,P28074,Q13616,O75376,O43819,Q86X55,Q9BZK7,P20618,Q8TED1,P28070,Q14145,P49721,P09601,P30519 15 +Transport of connexons to the plasma membrane 0.6302302951670419 1.767754257987243 0.0771019949479039 1.0 0.2841393710981124 2 Q9BUF5 1 +Gap junction assembly 0.6302302951670419 1.767754257987243 0.0771019949479039 1.0 0.2841393710981124 2 Q9BUF5 1 +Nr1h2 and nr1h3 mediated signaling 0.7773316371605643 1.763054152364169 0.0778913568121426 1.0 0.2841393710981124 7 Q8NB78 1 +Lysine catabolism 0.7768161500218372 1.760852934931592 0.0782632976456734 1.0 0.2841393710981124 7 Q02218,P49419 2 +Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.8035352784359194 1.7597649053469937 0.0784476757607874 1.0 0.2841393710981124 4 P61009 1 +Incretin synthesis secretion and inactivation 0.8035352784359194 1.7597649053469937 0.0784476757607874 1.0 0.2841393710981124 4 P61009 1 +Polymerase switching 0.5972340500562208 1.7590721076636744 0.0785652617585876 1.0 0.2841393710981124 14 P41440 1 +Switching of origins to a post replicative state 0.3992125192132826 1.7580298193341544 0.0787424356855472 1.0 0.2841393710981124 58 Q9UJX3,P28074,Q9H1A4,Q13616,O00231,Q13416,Q9Y619,P25205,P20618,Q9UJX4,Q99436,P28070,P24941,P49721,Q9UL46,Q9UBD5,Q16763 17 +Fcgr activation 0.6243918261433647 1.73797925959589 0.0822144683816714 1.0 0.2927951302156655 2 P07948 1 +Pregnenolone biosynthesis 0.6234187479727514 1.7330103948206128 0.0830938212385539 1.0 0.2936268709051506 2 P15121 1 +Endogenous sterols 0.6234187479727508 1.7330103948206104 0.0830938212385543 1.0 0.2936268709051506 2 Q16850 1 +Regulation of mecp2 expression and activity 0.664268603377199 1.7175292810017897 0.0858825091311841 1.0 0.298836077691161 11 Q14739,O75376,Q9BZK7,Q13555 4 +Fructose metabolism 0.6198507946805037 1.7147760096744031 0.0863863015762826 1.0 0.2998242120866401 2 P15121 1 +Retrograde transport at the trans golgi network 0.5378801452019146 1.693530593931024 0.0903545165370576 1.0 0.3118182456103683 17 Q8N2H4,Q9UP83,P40616,Q14746,O43752 5 +Loss of function of mecp2 in rett syndrome 0.7724550384068956 1.658004842680729 0.0973164889222661 1.0 0.3293788855830548 6 O75376,Q9BZK7 2 +Activation of atr in response to replication stress 0.5114223871664465 1.6544312457754338 0.0980399222387611 1.0 0.331006074093243 20 P40938,Q9HAW4,Q9Y619,P25205,P24941,Q13416,O14757,Q9UBD5 8 +Antigen processing cross presentation 0.3999542289631135 1.6162735313339611 0.1060351868968276 1.0 0.3485108311500552 49 P04439,P61619,P28074,Q03519,P20618,Q99436,P28070,O75396,P49721,Q9UL46,Q03518 11 +Hiv elongation arrest and recovery 0.4943987316571959 1.6146114472758026 0.1063948648890598 1.0 0.3488523935304749 22 P23193,P62487,P55199,P35269,Q8IXH7,Q8WX92,O15514,P19387,P50750,Q15369 10 +Acyl chain remodelling of pg 0.5977943561466044 1.601558112260474 0.1092533598104552 1.0 0.3539705054191472 2 Q8NF37 1 +Assembly of the hiv virion 0.5968212779759938 1.596545028888062 0.1103671608042138 1.0 0.3567317709406342 2 Q9NZ09 1 +Cdt1 association with the cdc6 orc origin complex 0.4257083039853778 1.5948666700695076 0.1107420542912369 1.0 0.3570973098185513 39 P60900,P28074,O00231,Q13416,Q9Y619,P20618,Q15008,Q9Y5N6,Q99436,P28070,P25787,P49721,Q9UL46,Q9UBD5 14 +G1 s specific transcription 0.6612395645888589 1.5865736678028832 0.1126092352105905 1.0 0.3605610254160691 10 P31350,P00374,Q9Y619,Q13547,Q5TKA1 5 +Pcp ce pathway 0.3991414881743392 1.5782179266686025 0.1145155532558068 1.0 0.3649514360769172 48 P60900,Q15008,P28072,Q9UL46,P63000,O95782,Q99436,P49721,P61586,Q00610,P28074,P25787,P28070,O94973,O00231,P20618,Q96CW1,P63010,P17252 19 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.6857001759821976 1.5720410622842709 0.1159410285546369 1.0 0.3686330138660251 9 Q9HA64,P38435,O60725,O43681,Q8NBJ7,Q9BU89 6 +Hedgehog off state 0.4073378001230767 1.5445717060482156 0.1224498943921776 1.0 0.3857313070460285 44 P60900,P10644,Q15008,P28072,Q9UL46,Q92530,Q9BUF5,Q99436,P49721,P51665,P28074,Q96J02,P25787,P48729,O43242,P25788,Q13616,O00231,P20618,Q99460,P28070,P17252 22 +Regulation of ifna signaling 0.5844956211482282 1.5329295947173531 0.1252932030693538 1.0 0.3904358032892229 2 P18031 1 +Cell cycle checkpoints 0.3256836611694044 1.5315654338043718 0.125629707842013 1.0 0.3904358032892229 137 Q8NFH4,Q9UJX2,P60900,Q96EE3,P49736,Q9Y619,P25205,Q8WXE1,Q15008,Q9Y5N6,Q9UQ84,P28072,Q03188,Q9UL46,Q6IPU0,Q9UBD5,Q92674,Q9UJX3,P30154,Q9H1A4,P38398,Q96IY1,P33993,Q99436,P49721,Q92878,P28074,P14635,O60566,O43684,Q9NQS7,Q9UJX4,Q15691,P25787,P28070,Q13416,Q16763,O14757,Q99728,P40938,P42771,P61981,Q8NFH3,Q9HAW4,Q9Y6G9,P20618,Q2NKX8,Q53HL2,O43264,P50748,P46060,P24941,O00231,P49959,O96028,Q12769 56 +Hedgehog on state 0.4162085492621972 1.5286729871329077 0.1263455321363358 1.0 0.3904358032892229 40 P28074,O43791,P20618,Q96J02,P49721,P28070 6 +Polymerase switching on the c strand of the telomere 0.5275822718122807 1.5267288290240983 0.1268284555796135 1.0 0.3904358032892229 16 P41440 1 +Synthesis of pips at the er membrane 0.6636857299460057 1.525820091066177 0.1270546757220891 1.0 0.3904358032892229 3 Q13614 1 +Caspase activation via death receptors in the presence of ligand 0.582549464807001 1.5228666951139185 0.1277920596543813 1.0 0.3904358032892229 2 P49327 1 +Caspase activation via extrinsic apoptotic signalling pathway 0.582549464807001 1.5228666951139185 0.1277920596543813 1.0 0.3904358032892229 2 P49327 1 +Regulation by c flip 0.582549464807001 1.5228666951139185 0.1277920596543813 1.0 0.3904358032892229 2 P49327 1 +Regulation of hmox1 expression and activity 0.4013504995515992 1.515280309207648 0.1297014327067396 1.0 0.3921145156327191 45 P28074,Q13616,P20618,P49721,Q14145,P28070,P09601 7 +Scf skp2 mediated degradation of p27 p21 0.4147497083526896 1.51517309656877 0.1297285742851031 1.0 0.3921145156327191 40 P28074,Q13616,P20618,Q99436,P28070,P24941,P49721,Q9UL46,P11802 9 +Lagging strand synthesis 0.5098860617114871 1.5132124009933532 0.130225715235793 1.0 0.3921145156327191 17 P41440 1 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.7366094167775799 1.5088886237291648 0.1313272475335569 1.0 0.3945602767307746 6 P09601,Q96J02 2 +Rac1 gtpase cycle 0.4125821119811522 1.4951169531103428 0.1348839221543305 1.0 0.4034685741633922 40 Q96RT1,Q9Y4F1,Q96N67,Q9UQB8,Q96F07,Q15758 6 +Fceri mediated ca 2 mobilization 0.6554185593770269 1.4879990152373834 0.1367511533351477 1.0 0.4063803336582611 3 O43865,P62993 2 +Erythropoietin activates ras 0.6554185593770268 1.4879990152373823 0.1367511533351479 1.0 0.4063803336582611 3 P62993,P46109 2 +Signaling by erythropoietin 0.6554185593770268 1.4879990152373823 0.1367511533351479 1.0 0.4063803336582611 3 P62993,P46109 2 +Adenylate cyclase inhibitory pathway 0.652822842310187 1.4761123336491633 0.1399137384240543 1.0 0.413974705445575 3 P63096,P08754 2 +Mastl facilitates mitotic progression 0.7326581354440107 1.47120136498829 0.1412366681620207 1.0 0.4160838344989121 4 P14635 1 +Hdr through homologous recombination hrr 0.4486458837169882 1.4500382666327147 0.147047848438794 1.0 0.4296732820134663 27 P40938,P38398,P49005,Q9NR33,Q9UQ84,O14757,Q96B01,P49959,P41440 9 +Dna replication 0.3599999288810146 1.449035445039666 0.1473276842504101 1.0 0.4296732820134663 86 Q9Y619,P25205,Q9BRX5,Q9UL46,P41440,Q9UBD5,Q9UJX3,Q9H1A4,Q99436,P49721,P28074,Q9UJX4,Q9BRT9,P28070,Q13416,Q16763,P40938,Q13616,P20618,P49005,Q9NR33,P24941,O00231 23 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.3624339168545893 1.4473296117479786 0.1478046293872039 1.0 0.4298625042305888 67 Q9NPL8,P13073,O43676,P09669,O75964,Q9GZY4,P03886,O43819,O95168,O96000,Q9P0J0,P00846,Q16718,P56134 14 +Hdms demethylate histones 0.7211223703338946 1.4441779953816585 0.148688912965095 1.0 0.4315142069880629 6 Q8NB78 1 +Activation of nmda receptors and postsynaptic events 0.5113908863669195 1.4258111885550662 0.1539228504195435 1.0 0.4385228699028937 16 Q9BUF5,P63000,P07196,P52292,Q13131,P54619,Q13555,P51812,P17252 9 +Unwinding of dna 0.6796981664642677 1.4245787122867772 0.1542790171766659 1.0 0.4385228699028937 8 Q9BRT9,P25205 2 +Downregulation of erbb2 signaling 0.7161286077667386 1.42328698319282 0.1546529788536164 1.0 0.438558551260567 6 Q96RT1 1 +Deubiquitination 0.3580024555753598 1.4144228066136173 0.1572377976532086 1.0 0.4449633941887481 83 Q8NB78,P28074,P85037,P20618,P49721,Q14145,P28070,Q9HBM6,Q96K76,P61586 10 +Metabolism of steroids 0.3848003539291499 1.4060691213685028 0.1597036005448853 1.0 0.4491457961715949 47 Q14739,Q15392,Q86X55,P38435,Q9BZK7,P56937,Q53GQ0,O75845 8 +Degradation of gli1 by the proteasome 0.4043143542827855 1.3991636089299804 0.1617639265645483 1.0 0.4530718600288375 39 Q13616,P28074,P20618,Q96J02,P49721,P28070 6 +Tp53 regulates transcription of dna repair genes 0.430650487731958 1.3948159968354126 0.1630713337036451 1.0 0.4552999992594358 30 Q9BXW9,P23193,P62487,Q9NVI1,P55199,P38398,Q8IXH7,P35269,Q8WX92,O15514,P19387,O14757,P50750,Q15369,P43246 15 +Regulation of pten stability and activity 0.3990480514221002 1.390755170845732 0.1642996813023449 1.0 0.456425183903052 41 P28074,P20618,P49721,P14373,P28070,Q9UL46 6 +Mismatch repair 0.6192937847288345 1.3803466337804005 0.1674799430016029 1.0 0.4626752975319854 10 Q9UQ84 1 +Protein ubiquitination 0.449379463599635 1.3743002443493797 0.1693484905023876 1.0 0.4655290602017684 24 Q6PD62,O75381,P04439,P45974,P49427,Q9BUN8,Q14527,Q16763,Q93009 9 +Carboxyterminal post translational modifications of tubulin 0.6304347826086998 1.3734110658166978 0.1696245915837821 1.0 0.4655290602017684 3 Q9BUF5,Q14166 2 +Cdc6 association with the orc origin complex 0.7039922103213269 1.353492013959574 0.1758984996125785 1.0 0.4737768039550442 4 Q13416,Q9Y619,Q9UBD5 3 +Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.7000564527725185 1.3459935835394723 0.1783045859053809 1.0 0.476319102695614 5 Q13555,P07196 2 +Signaling by the b cell receptor bcr 0.3918737661384385 1.345558138372597 0.1784450597342073 1.0 0.476319102695614 42 P60900,Q15008,P28072,Q9UL46,Q92530,P62993,P07948,Q99436,P49721,P51665,P28074,Q13586,O43865,P25787,O43242,P25788,Q13616,O00231,P20618,P28070 20 +Notch hlh transcription pathway 0.6967505467262687 1.3421487911514924 0.1795477565305794 1.0 0.4783264451322467 6 O75376,Q9BZK7 2 +Intra golgi and retrograde golgi to er traffic 0.3507881982683224 1.3292545118019792 0.1837640161126899 1.0 0.4831332097402726 85 Q6NUQ1,Q9NRW7,O43752,Q9NP72,O75935,Q9Y3B3,O14653,O75396,Q9UJW0,O60476,Q14746,P40616,P24390,P83436,Q8N2H4,P20645,Q9UP83,P52732,O95249,Q16706 20 +E2f enabled inhibition of pre replication complex formation 0.6932073467123256 1.3273066668807438 0.1844072593758554 1.0 0.4831332097402726 6 P14635,Q9Y619,Q9UBD5 3 +Mrna decay by 3 to 5 exoribonuclease 0.5094288286631133 1.3267509385703635 0.1845910846041407 1.0 0.4831332097402726 15 Q13868,Q96B26,Q9NQT5,Q969T7 4 +Copi mediated anterograde transport 0.3743988053556912 1.3266188912188452 0.1846347834983692 1.0 0.4831332097402726 48 Q14746,Q9UP83,O14653,Q12955,O95249,P24390,O75935,Q9Y3B3 8 +G1 s dna damage checkpoints 0.3963413117494605 1.3264442246725394 0.1846925982734804 1.0 0.4831332097402726 39 P42771,P28074,P20618,Q99436,P49721,P24941,P28070,Q9UL46,O14757 9 +Signaling by hedgehog 0.363032040591033 1.3227414280153174 0.1859213814447364 1.0 0.4848886506512821 52 P28074,Q13616,O43791,P20618,Q96J02,Q9UBV2,P49721,P28070 8 +Signaling by erbb2 0.5837474650761953 1.3065306696819154 0.1913721562646948 1.0 0.4951528103099413 11 Q96RT1,P62993,P31751,P61586 4 +Rhoa gtpase cycle 0.3876361000383062 1.305648686193363 0.1916720556038482 1.0 0.4951528103099413 42 Q9P0I2,Q14739,Q96RT1,Q9Y4F1,Q96HY6,P41440,P30519 7 +Beta catenin independent wnt signaling 0.3641745444526774 1.3042174222815743 0.1921594612652355 1.0 0.4954735447368266 51 P60900,Q15008,P28072,Q9UL46,P63000,O95782,Q99436,P49721,P61586,Q00610,P28074,P25787,P28070,O94973,O00231,Q9HCE1,P20618,Q96CW1,P63010,P17252 20 +Signaling by notch 0.3580680430245521 1.301767742567304 0.1929957940092288 1.0 0.4959408507415486 58 P28074,Q13616,O75376,P20618,Q9BZK7,Q96J02,Q9UBV2,Q13547,P28070,P49721 10 +Cholesterol biosynthesis 0.4769870361592092 1.3004946885921769 0.193431475509167 1.0 0.4959408507415486 17 Q14739,Q15392,P56937 3 +The role of gtse1 in g2 m progression after g2 checkpoint 0.3813003163706933 1.2925562405263336 0.1961645826088769 1.0 0.4982653457700338 44 P60900,Q15008,P28072,Q9UL46,Q92530,Q9BUF5,Q99436,P49721,P51665,P28074,P14635,Q15691,P25787,O43242,P25788,P53350,O00231,P20618,Q99460,P28070 20 +Iron uptake and transport 0.470191361687378 1.2899587600626403 0.1970649771719568 1.0 0.4991851198538306 18 Q9Y5K8,Q13616,Q9Y487,P09601,P30519 5 +Endosomal vacuolar pathway 0.6116158338741104 1.2869454811634828 0.198113291303339 1.0 0.4991851198538306 3 P04439,P10321 2 +G2 m checkpoints 0.3473572123491432 1.2788137684899228 0.2009626442237353 1.0 0.5038842770609835 81 P49736,Q9Y619,P25205,Q9UQ84,Q9UL46,Q9UBD5,Q99436,P49721,P28074,P14635,P28070,Q13416,O14757,P40938,P61981,Q9HAW4,P20618,P24941,O00231,P49959,O96028 21 +Regulation of runx3 expression and activity 0.3972544450863369 1.2694946732925665 0.2042646891667363 1.0 0.5102876117645209 36 P42771,P60900,P28074,O00231,P20618,Q15008,Q99436,P28070,P28072,P49721,Q9UL46,Q92530,P51665,P25787,O43242,P25788 16 +Dna replication pre initiation 0.3532738493004724 1.2652755595279217 0.2057725646237536 1.0 0.5112454975351547 60 P60900,Q14181,P49736,Q9Y619,P25205,Q15008,Q9Y5N6,Q9UL46,Q9UBD5,P33993,Q99436,P49721,P28074,P56282,P25787,Q13416,O00231,P20618,Q9NR33,P24941,P28070 21 +Telomere c strand lagging strand synthesis 0.4540826284674943 1.2597729622495997 0.2077512760840574 1.0 0.5146579930932849 20 P41440 1 +Deadenylation dependent mrna decay 0.3990959763003874 1.2553742141049635 0.2093429455423701 1.0 0.514659598160255 35 Q9Y4Y9,P26196,Q96B26,Q9NQT5,Q15024,Q96C86,Q13868,P62312,P23588,Q969T7,Q6PGP7 11 +Nrage signals death through jnk 0.6799315197977678 1.254577243072753 0.2096322689022662 1.0 0.514659598160255 4 Q14344,P63000 2 +Cytochrome p450 arranged by substrate type 0.6044776119402977 1.2541487879086015 0.2097879300418634 1.0 0.514659598160255 3 Q16850,P22570 2 +Retrograde neurotrophin signalling 0.6576101029088539 1.2458883716295095 0.2128053797438651 1.0 0.5211248437533789 7 P50570,O95782,Q96CW1,P63010,O94973 5 +Rho gtpases activate wasps and waves 0.4791530912373659 1.224908525392994 0.2206096878932808 1.0 0.5392681259613531 16 Q9UQB8 1 +Heme degradation 0.6724216868099699 1.223722516586996 0.22105692255789 1.0 0.5393947090679104 4 P09601 1 +Circadian clock 0.5466261527058675 1.2207078414970185 0.2221966577208944 1.0 0.54120757344875 12 Q13616,P50416,Q86X55,Q9BZK7,P43490 5 +Dex h box helicases activate type i ifn and inflammatory cytokines production 0.5231916963996015 1.2146420313562674 0.2245026506876768 1.0 0.5448783194626178 2 Q9H2U1 1 +The citric acid tca cycle and respiratory electron transport 0.3336792890897582 1.2113434308132331 0.2257638101157599 1.0 0.5469659626960863 101 Q9NPL8,P13073,P03886,P00846,Q16718,Q02218,O43676,Q9H9P8,P48735,P09669,Q9GZY4,Q9P2R7,O95168,Q13423,O75964,O43819,O96000,P56134,Q9P0J0 19 +Negative regulation of notch4 signaling 0.384316382556029 1.2015781408640676 0.2295270147851915 1.0 0.5550972485230519 38 Q13616,P28074,P20618,P49721,P28070 5 +Heme signaling 0.6462590778745342 1.1967013399533624 0.2314229845874607 1.0 0.5577048603839159 7 P09601,Q86X55,Q9BZK7 3 +C type lectin receptors clrs 0.3685218374133543 1.19444191153128 0.2323051504863045 1.0 0.557719460492617 45 P60900,Q15008,P28072,Q9UL46,Q92530,P07948,Q99436,P49721,P51665,P49427,P28074,O43865,P25787,P28070,O43242,P25788,Q13616,P20618,O00231,P17252 20 +Resolution of sister chromatid cohesion 0.3475304008017307 1.193545768329497 0.2326556986952339 1.0 0.557719460492617 59 Q8NFH4,Q96EE3,Q29RF7,Q03188,Q6IPU0,P43034,Q92674,Q9BUF5,P30154,Q96IY1,Q8WVM7,P14635,O60566,Q8WUM0,O43684,Q9NQS7,Q15691,P52948,O14980,Q8N3U4,P30153,Q8NFH3,P53350,Q9Y6G9,Q2NKX8,Q53HL2,O43264,P50748,P46060,Q96FF9,O60216,Q12769 32 +Hiv transcription initiation 0.5203695213441368 1.190359713759552 0.2339050400499984 1.0 0.5597306572424524 13 Q92804,P35269,O15514,Q9HBM6,P19387 5 +Transcription of the hiv genome 0.4059481331376521 1.1783058602304266 0.2386746923706786 1.0 0.5675263577286237 29 P23193,P62487,Q92804,P35269,Q8IXH7,Q8WX92,O15514,P19387,P50750,Q9HBM6,Q15369 11 +Regulation of runx2 expression and activity 0.3776632869780063 1.1738963462185836 0.2404365461479991 1.0 0.5675536212760351 40 Q13616,P28074,P20618,P49721,P28070 5 +Transport to the golgi and subsequent modification 0.3371404290292011 1.1694103732474537 0.2422383324686414 1.0 0.5679875598235549 71 Q5JRA6,O75935,Q9Y3B3,O14653,Q12955,O75396,Q9UJW0,O60476,Q12907,P26572,Q14746,P24390,Q96PC5,P83436,Q9UP83,O95249,P62820,Q16706,O94979 19 +Clec7a dectin 1 signaling 0.372693394189766 1.165778170929012 0.2437041451479213 1.0 0.5679875598235549 42 P60900,P49427,P28074,Q13616,O00231,P20618,Q15008,O43865,Q99436,P28070,P25787,P49721,Q9UL46 13 +Degradation of dvl 0.3851385279344381 1.1638480639017366 0.2444855900451517 1.0 0.5679875598235549 36 P60900,P28074,O00231,P20618,Q15008,Q99436,P28070,P28072,P49721,Q9UL46,Q92530,P51665,P25787,O43242,P25788 15 +Regulation of ras by gaps 0.3851385279344381 1.1638480639017366 0.2444855900451517 1.0 0.5679875598235549 36 P60900,P28074,O00231,P20618,Q15008,Q99436,P28070,P28072,P49721,Q9UL46,Q92530,P51665,P25787,O43242,P25788 15 +Degradation of axin 0.3883855238543819 1.1634105689825605 0.2446629634512804 1.0 0.5679875598235549 35 P60900,P28074,O00231,P20618,Q15008,Q99436,P28070,P28072,P49721,Q9UL46,Q92530,P51665,P25787,O43242,P25788 15 +G protein mediated events 0.5751324820312307 1.1631327755392906 0.2447756360193151 1.0 0.5679875598235549 10 P63096,P10644,P52292,P08754,O43865,Q13555,P17252 7 +Interleukin 1 signaling 0.3758508227346072 1.1574100865592112 0.2471048550217203 1.0 0.569843587758838 40 Q13616,P28074,P20618,P49721,P28070 5 +Fceri mediated nf kb activation 0.3736932788059444 1.155600177090555 0.2478447355605442 1.0 0.569843587758838 41 P60900,P49427,P28074,P07948,Q13616,O00231,P20618,Q15008,Q99436,P28070,P28072,P49721,Q9UL46,Q92530,P51665,P25787,O43242,P25788 18 +Neurotransmitter receptors and postsynaptic signal transmission 0.4068804173468953 1.155279259479582 0.2479760864915454 1.0 0.569843587758838 28 P63096,Q9BUF5,P63000,P10644,P52292,P07196,O95782,P08754,Q96CW1,Q13131,P54619,Q13555,P51812,P63010,P17252,O94973,Q9UM54 17 +Antigen activates b cell receptor bcr leading to generation of second messengers 0.655631288542684 1.15483575672757 0.2481576914433649 1.0 0.569843587758838 4 O43865,Q13586,P62993 3 +Vldlr internalisation and degradation 0.6506700260582108 1.149368102085664 0.2504042272409763 1.0 0.5726558281650874 6 O95782,Q96CW1,O94973,P63010 4 +Signaling by ptk6 0.5330877274269235 1.148791697404803 0.2506418837350126 1.0 0.5726558281650874 12 P24941,Q8IZL8,P61586,P11802,O75525 5 +Fc epsilon receptor fceri signaling 0.3587185423778133 1.1460810976948623 0.2517615979713916 1.0 0.5735552202736462 47 P60900,P62993,P63000,P49427,P28074,Q13616,O00231,P20618,Q15008,O43865,Q99436,P28070,P25787,P49721,Q9UL46 15 +Cross presentation of soluble exogenous antigens endosomes 0.3830097606547048 1.1453884900397362 0.2520482641016286 1.0 0.5735552202736462 36 P60900,P28074,O00231,P20618,Q15008,Q99436,P28070,P28072,P49721,Q9UL46,Q92530,P51665,P25787,O43242,P25788 15 +Tnfr2 non canonical nf kb pathway 0.3777822420166017 1.143354788145981 0.2528913159669583 1.0 0.5735552202736462 38 Q13616,P28074,P20618,P49721,P28070 5 +Dectin 1 mediated noncanonical nf kb signaling 0.3777822420166017 1.143354788145981 0.2528913159669583 1.0 0.5735552202736462 38 Q13616,P28074,P20618,P49721,P28070 5 +Termination of translesion dna synthesis 0.451723711635118 1.1377985751610786 0.2552046000813663 1.0 0.5735552202736462 17 P41440 1 +Homology directed repair 0.3650096024518826 1.1366595154232388 0.2556806497154951 1.0 0.5735552202736462 44 P40938,Q9UNS1,Q9HAW4,P18887,P38398,P49005,P49959,Q9NR33,Q9UQ84,O14757,Q96B01,P24941,Q9NY27,P41440,O96028 15 +Metabolism of polyamines 0.381949410941601 1.13620717664174 0.2558698676967654 1.0 0.5735552202736462 36 P60900,P28074,O00231,P20618,Q15008,Q99436,P28070,P28072,P49721,Q9UL46,Q92530,P51665,P25787,O43242,P25788 15 +Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.4415520422906321 1.135646964655577 0.2561043449905655 1.0 0.5735552202736462 19 P41440 1 +Rna polymerase iii chain elongation 0.6507627393703376 1.13489815099099 0.2564179947468381 1.0 0.5735552202736462 4 O15160,O14802,P62875 3 +Rna polymerase iii transcription initiation from type 3 promoter 0.6507627393703376 1.13489815099099 0.2564179947468381 1.0 0.5735552202736462 4 O15160,O14802,P62875 3 +Mitotic prometaphase 0.3349434115678611 1.1346595176507586 0.2565180052667193 1.0 0.5735552202736462 86 Q8NFH4,P67870,Q96EE3,Q14203,Q13561,Q03188,Q96CW5,Q9NTJ3,O75935,Q6IPU0,Q92674,Q9BPX3,P43034,P30154,Q96IY1,P14635,O60566,O43684,Q9NQS7,Q9H6D7,Q15691,Q8N3U4,Q15021,Q8NFH3,P61981,Q9Y6G9,Q2NKX8,Q68CZ6,Q53HL2,O43264,P50748,P46060,Q96FF9,O60216,P17252,Q12769 36 +E2f mediated regulation of dna replication 0.5302385109930504 1.1336951064418177 0.2569224630404676 1.0 0.5735552202736462 12 P30154,Q14181,P14635,Q9Y619,Q13416,Q9UBD5 6 +Degradation of beta catenin by the destruction complex 0.3588303973942748 1.126064476789142 0.2601382287974552 1.0 0.5781242316138341 46 P28074,Q13616,P20618,Q13547,P49721,P28070,Q9UL46 7 +Apc c mediated degradation of cell cycle proteins 0.3434419066741443 1.125822465180042 0.2602406731751423 1.0 0.5781242316138341 55 Q9UJX3,P28074,Q9H1A4,Q13616,P14635,P20618,O60566,Q9UJX4,Q99436,P28070,P24941,P49721,Q9UL46,Q16763 14 +Transcription of e2f targets under negative control by dream complex 0.648132256712751 1.1241346492647288 0.2609559080006614 1.0 0.5787705016469953 4 Q5TKA1 1 +Protein protein interactions at synapses 0.565629190394236 1.1166302991171742 0.2641524310568139 1.0 0.5849089544829452 10 Q9Y2J2,P41440 2 +Dag and ip3 signaling 0.6422350444565282 1.1142236053009156 0.2651832710616999 1.0 0.5862398407263513 6 P52292,O43865,Q13555,P17252 4 +Downstream signaling events of b cell receptor bcr 0.3739510695049073 1.109384836872222 0.2672642008265087 1.0 0.5898840937335889 38 Q13616,P28074,P20618,P49721,P28070 5 +Asymmetric localization of pcp proteins 0.3786400878375239 1.107614250246024 0.2680284464667197 1.0 0.5906151873676991 36 P60900,P28074,O00231,P20618,Q15008,Q99436,P28070,P28072,P49721,Q9UL46,Q92530,P51665,P25787,O43242,P25788 15 +Transcriptional regulation by runx1 0.3310769676067632 1.1020828448497988 0.2704256567895702 1.0 0.5930234660144272 70 Q68CP9,Q16625,P28074,Q03164,Q9HCE1,O00231,P20618,Q96J02,Q13547,Q99436,P28070,P49721,Q9UL46,Q9HCL2,Q12824 15 +Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.585050164912888 1.0993237847877564 0.2716268613880086 1.0 0.5937484598289163 9 P45974,P49427,A0AVT1,Q16763,Q93009 5 +Cellular response to hypoxia 0.372301513546498 1.0948019816955763 0.2736033980734065 1.0 0.5968448305013088 38 P60900,P28074,O00231,P20618,Q15008,Q99436,P28070,P28072,P49721,Q9UL46,Q92530,P51665,P25787,O43242,Q15369,P25788 16 +Homologous dna pairing and strand exchange 0.4447795902832428 1.0933703034870292 0.2742312466567327 1.0 0.5968448305013088 17 P40938,P38398,Q9UQ84,Q96B01,P49959,O14757,Q99728,Q92878 8 +Assembly and cell surface presentation of nmda receptors 0.6383726655920523 1.090607675133132 0.2754455508846909 1.0 0.5977770254721625 5 P07196 1 +Pp2a mediated dephosphorylation of key metabolic factors 0.5684620376378944 1.089123656108864 0.2760993592723331 1.0 0.5977770254721625 3 P30153,P30154 2 +Platelet sensitization by ldl 0.5684620376378944 1.089123656108864 0.2760993592723331 1.0 0.5977770254721625 3 P30153,P30154 2 +Rho gtpases activate formins 0.3396935907188116 1.0861263594963466 0.2774230917623388 1.0 0.5988646872845188 55 Q8NFH4,Q96EE3,Q03188,Q6IPU0,P43034,Q92674,Q9BUF5,P63000,P30154,Q96IY1,P61586,O60566,Q8WUM0,O43684,Q9NQS7,Q15691,P35080,Q8NFH3,Q9Y6G9,Q2NKX8,Q53HL2,O43264,P50748,P46060,Q12769 25 +Complex i biogenesis 0.3845111928797198 1.0815978963518231 0.279431239674881 1.0 0.5988646872845188 33 Q9NPL8,O43676,P03886,O95168,O96000,Q9GZY4,Q9P0J0 7 +Tp53 regulates transcription of genes involved in cytochrome c release 0.5665763376973982 1.0805212768096393 0.2799101173064662 1.0 0.5988646872845188 3 Q13794 1 +Pka mediated phosphorylation of creb 0.5663765929853579 1.0796103774550814 0.2803157183279876 1.0 0.5988646872845188 3 P17252 1 +Creb1 phosphorylation through the activation of adenylate cyclase 0.5663765929853579 1.0796103774550814 0.2803157183279876 1.0 0.5988646872845188 3 P17252 1 +Pka activation in glucagon signalling 0.5663765929853579 1.0796103774550814 0.2803157183279876 1.0 0.5988646872845188 3 P17252 1 +Cyclin d associated events in g1 0.5577288228292329 1.0780930595186708 0.2809922286378974 1.0 0.5988646872845188 10 P42771,P11802,P30154,Q13616 4 +E3 ubiquitin ligases ubiquitinate target proteins 0.4545796660082162 1.0728865155451617 0.2833220369008637 1.0 0.6012503101165231 16 Q6PD62,O75381,Q14527 3 +Tcr signaling 0.3605008033782606 1.072637081264887 0.2834339805021439 1.0 0.6012503101165231 43 P60900,P49427,P28074,Q13616,O00231,P41240,P20618,Q15008,Q99436,P28070,P25787,P49721,Q9UL46 13 +Parasite infection 0.4164995652514817 1.0606893097895804 0.2888311198024129 1.0 0.6089825915420178 22 Q9UQB8 1 +Interleukin 1 family signaling 0.3613183523528877 1.0606149851533793 0.2888649096244029 1.0 0.6089825915420178 42 Q13616,P28074,P20618,P49721,P28070 5 +Estrogen dependent gene expression 0.3841135188221085 1.057442632352518 0.2903096233822679 1.0 0.6099234413401273 32 P62487,Q9HCE1,P52292,P35269,Q86X55,Q15648,Q8N3U4,O15514,Q15185,Q13547,P50750,P19387,Q9HCL2 13 +Hedgehog ligand biogenesis 0.3644677055053317 1.0545993036593342 0.2916086224040248 1.0 0.6099234413401273 40 Q9UBV2,P28074,P49721 3 +Stabilization of p53 0.3691414284651978 1.054345841256627 0.2917246082242113 1.0 0.6099234413401273 37 P42771,P28074,P20618,Q99436,P49721,P28070,Q9UL46 7 +Metabolism of folate and pterines 0.5968320085704308 1.0520871996092256 0.2927595443832618 1.0 0.6099234413401273 8 P41440 1 +Ticam1 rip1 mediated ikk complex recruitment 0.4917288355497768 1.0517391905614657 0.2929192251224348 1.0 0.6099234413401273 2 Q13546 1 +Ikk complex recruitment mediated by rip1 0.4917288355497768 1.0517391905614657 0.2929192251224348 1.0 0.6099234413401273 2 Q13546 1 +Rna polymerase iii transcription termination 0.6287743015334548 1.051148527562169 0.2931903791937378 1.0 0.6099234413401273 5 O15160,O14802,P62875 3 +Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.5746316641100855 1.0508323089817038 0.2933356140169527 1.0 0.6099234413401273 9 P14635,Q86X55 2 +Neurexins and neuroligins 0.6236136446372683 1.0369521472698262 0.2997581591750589 1.0 0.6185629789936162 6 Q9Y2J2,Q9HCM4 2 +Cell cycle 0.2436369646092613 1.0339132410622458 0.3011767243116661 1.0 0.6205514380077228 288 Q8NFH4,P25205,P42166,Q9UQ84,P41440,Q6IPU0,Q9UBD5,Q92674,P62487,Q96IY1,Q99436,P49721,P28074,Q9NQS7,Q9UJX4,Q13416,O14757,P40938,P42771,P61981,Q9HAW4,P49005,P50748,P24941,P28070,O00231,P49736,Q9NTJ3,O75935,Q9ULW0,Q9UJX3,P31350,Q9H1A4,P38398,P04183,O60763,P50402,P14635,Q15691,P56282,Q8N3U4,Q14739,Q8NFH3,Q9Y6G9,Q2NKX8,Q68CZ6,O15514,O75694,Q9UJX2,Q96EE3,Q14203,Q15008,Q03188,O94901,Q9BPX3,P00374,P62875,P33993,Q8NC56,Q5TKA1,P11802,Q92878,Q8WXH0,O60566,O43684,Q9H6D7,Q9BRT9,P25787,Q16763,Q99728,Q15021,Q13616,P54652,Q9NX24,P20618,Q53HL2,O43264,P46060,O60216,P17252,Q12769,P67870,P60900,Q14181,Q9Y619,Q8WXE1,Q9BRX5,Q9Y5N6,Q13547,Q13561,P28072,Q96CW5,Q9UL46,P42167,P43034,P31751,P30154,Q8NFH5,Q92973,Q9NR33,P62820,Q96FF9,P49959,P19387,O96028 105 +Synthesis of pips at the late endosome membrane 0.5555920190134451 1.0305295390130793 0.3027614931771443 1.0 0.6224711194534839 3 Q13614 1 +Translation of sars cov 2 structural proteins 0.4475076840247928 1.029510935387419 0.3032396437932754 1.0 0.6224711194534839 16 P26572,Q13724,P78362,Q16706,P04843,P39656,P48729 7 +Regulation of kit signaling 0.6247971437844887 1.0290046525395566 0.3034774885898583 1.0 0.6224711194534839 4 P07948,P17252,P62993 3 +Leishmania infection 0.3751563785786994 1.0268338860710888 0.3044986901793016 1.0 0.6232371056955318 34 Q9UQB8,P09601 2 +Cell cycle mitotic 0.2709919753644815 1.023088740052231 0.30626589029186 1.0 0.6253692729911633 240 Q8NFH4,P25205,P42166,P41440,Q6IPU0,Q9UBD5,Q92674,Q96IY1,Q99436,P49721,P28074,Q9NQS7,Q9UJX4,Q13416,P40938,P42771,P61981,P49005,P50748,P24941,P28070,O00231,P49736,Q9NTJ3,O75935,Q9ULW0,Q9UJX3,P31350,Q9H1A4,P04183,O60763,P50402,P14635,Q15691,P56282,Q8N3U4,Q14739,Q8NFH3,Q9Y6G9,Q2NKX8,Q68CZ6,O75694,Q9UJX2,Q96EE3,Q14203,Q15008,Q03188,Q9BPX3,P00374,P33993,Q8NC56,Q5TKA1,P11802,O60566,O43684,Q9H6D7,Q9BRT9,P25787,Q16763,Q15021,Q13616,P20618,Q53HL2,O43264,P46060,O60216,P17252,Q12769,P67870,P60900,Q14181,Q9Y619,Q9BRX5,Q9Y5N6,Q13547,Q13561,P28072,Q96CW5,Q9UL46,P42167,P43034,P31751,P30154,Q8NFH5,Q92973,Q9NR33,P62820,Q96FF9 88 +Mitotic g2 g2 m phases 0.3255733298073544 1.0164719484146232 0.3094046990469408 1.0 0.6296809584912655 78 P60900,Q14203,Q15008,Q13561,P28072,Q96CW5,Q9UL46,O75935,Q9ULW0,P43034,P30154,Q99436,P49721,Q5TKA1,P28074,P14635,Q9H6D7,Q15691,P25787,P28070,P61981,Q13616,P20618,Q68CZ6,P24941,O00231,P17252 27 +Integrin signaling 0.6191808962789879 1.0118516735591447 0.3116089787255163 1.0 0.6296809584912655 5 Q9Y490,P62993,P41240 3 +Platelet aggregation plug formation 0.6191808962789879 1.0118516735591447 0.3116089787255163 1.0 0.6296809584912655 5 Q9Y490,P62993,P41240 3 +Post chaperonin tubulin folding pathway 0.6028374780453014 1.0098019104473803 0.3125902046759354 1.0 0.6298183974125676 7 Q9BUF5,Q99426,Q9BVA1,P36404,Q15813 5 +Fanconi anemia pathway 0.6182859881691737 1.0081941437607436 0.3133612687565821 1.0 0.6298183974125676 5 Q9BXW9,Q8WXE1,Q9NVI1 3 +Constitutive signaling by egfrviii 0.550380991466445 1.0068940089511216 0.3139857113200484 1.0 0.6298183974125676 3 P62993 1 +Signaling by egfr in cancer 0.550380991466445 1.0068940089511216 0.3139857113200484 1.0 0.6298183974125676 3 P62993 1 +Constitutive signaling by ligand responsive egfr cancer variants 0.550380991466445 1.0068940089511216 0.3139857113200484 1.0 0.6298183974125676 3 P62993 1 +Transcriptional regulation by runx3 0.3572256119453453 1.0057670490660575 0.3145276414058777 1.0 0.6299790056940048 41 P42771,P28074,P25440,P20618,Q99436,P28070,P49721,Q9UL46 8 +Separation of sister chromatids 0.3166761471991774 0.9890000919465448 0.3226630966820749 1.0 0.6453261933641499 101 Q8NFH4,Q9UJX2,P60900,Q96EE3,Q15008,P28072,Q03188,Q9UL46,Q6IPU0,Q92674,P43034,Q9UJX3,P30154,Q9H1A4,Q96IY1,Q99436,P49721,P28074,O60566,O43684,Q9NQS7,Q9UJX4,Q15691,P25787,P28070,Q16763,Q8N3U4,Q8NFH3,Q9Y6G9,P20618,Q2NKX8,Q53HL2,O60216,O43264,P50748,P46060,Q96FF9,O00231,Q12769 39 +Nef mediated cd8 down regulation 0.6112467966276843 0.9859511693948022 0.3241570754030394 1.0 0.6463429943841064 6 O95782,Q96CW1,P63010 3 +Nef mediated cd4 down regulation 0.6112467966276843 0.9859511693948022 0.3241570754030394 1.0 0.6463429943841064 6 O95782,Q96CW1,P63010 3 +Activation of the pre replicative complex 0.4097681618043307 0.9846181026167562 0.3248116942499863 1.0 0.6463429943841064 21 Q14181,P49736,Q9Y619,P25205,Q9NR33,P33993,P56282,P24941,Q13416,Q9UBD5 10 +Unfolded protein response upr 0.3548059948979655 0.9840476931992768 0.3250920634761187 1.0 0.6463429943841064 41 Q96B26,Q9NQT5,O94979,O14653,Q15024,Q13217,Q9NWM8,O95070,Q13868,Q92945,P35611,O95453,P51858,Q9Y5M8,O43731,P05198 16 +Inactivation of cdc42 and rac1 0.5447033869811182 0.9812113936717376 0.3264885066940244 1.0 0.6463429943841064 3 O94813 1 +Hiv transcription elongation 0.3924711026074829 0.9753409049097168 0.3293911864621275 1.0 0.6502019946951403 25 P23193,P62487,P55199,P35269,Q8IXH7,Q8WX92,O15514,P19387,P50750,Q15369 10 +Recognition of dna damage by pcna containing replication complex 0.4253354243338962 0.9700924435534704 0.3320004152133826 1.0 0.6544054427038352 17 P41440 1 +Maturation of sars cov 1 spike protein 0.6068146372940886 0.9614519641118188 0.3363249671450696 1.0 0.6606893455344824 5 Q13724 1 +Translation of sars cov 1 structural proteins 0.6068146372940886 0.9614519641118188 0.3363249671450696 1.0 0.6606893455344824 5 Q13724 1 +Asparagine n linked glycosylation 0.3073243686043831 0.9506655734255576 0.3417741696242276 1.0 0.6653411800740333 109 Q5JRA6,Q9NP73,O60762,Q9NYU2,Q9NR45,O75935,Q9BT22,Q9Y3B3,Q92538,Q8WU17,O14653,Q12955,Q96AA3,Q9UBV2,O75396,Q9UJW0,O60476,Q12907,P26572,Q14746,Q13724,P24390,Q96PC5,P83436,Q9UP83,O95249,P34949,P62820,Q16706,O94979 30 +Pcna dependent long patch base excision repair 0.417920521880721 0.949432461139377 0.3424007071312163 1.0 0.6653411800740333 18 P41440 1 +Regulation of tp53 activity 0.3263503025751863 0.9441550056143152 0.3450904441163769 1.0 0.6667186484061446 54 Q8TBX8,P67870,Q92804,Q13131,Q96KQ7,Q13547,Q9UQ84,Q93009,Q9ULW0,Q00535,P31751,P30154,P38398,Q9HBM6,Q9H9B1,Q92878,O14744,O14757,Q99728,P40938,P42771,P42345,P54619,P24941,P49959 25 +Sars cov 2 infection 0.3995372138486017 0.9428666544176052 0.3457491129202188 1.0 0.6670463790992623 22 P26572,Q13724,P78362,P04843,P39656,Q16706,Q99570 7 +Dna damage bypass 0.4032015985890769 0.9400542131974292 0.3471897531279715 1.0 0.6672675668245379 21 P41440 1 +Maturation of sars cov 2 nucleoprotein 0.6019885823425698 0.9368896830076204 0.3488153066784769 1.0 0.6672675668245379 4 P78362,P48729 2 +Trna modification in the nucleus and cytosol 0.5482510775952781 0.9292428303320328 0.3527632555091684 1.0 0.6729637489713367 9 O75648,Q5VV42,Q9H974 3 +Antigen presentation folding assembly and peptide loading of class i mhc 0.4416624502806639 0.9232842613951012 0.3558590875380787 1.0 0.6761348402846157 15 P27797,P04439,Q9NZ08,Q03519,Q15436,Q03518,O95487,O95486,P10321,O94979,P51572 11 +Transcriptional regulation of granulopoiesis 0.5818013605310695 0.9205361445963092 0.3572926538522472 1.0 0.6778124893664328 7 Q03164 1 +Response of eif2ak1 hri to heme deficiency 0.529433986340238 0.912564843942899 0.3614714512145847 1.0 0.6789356432982984 3 P05198 1 +Transcriptional regulation by tp53 0.2947768971057484 0.9109685176073512 0.3623119618591759 1.0 0.6789356432982984 118 P13073,Q8TBX8,Q92804,Q86X55,P00390,Q13131,Q96KQ7,Q13547,Q9UQ84,Q93009,Q9ULW0,Q00535,Q9BXW9,P09669,P62487,P31751,P62875,P30154,P38398,Q8IXH7,P50750,Q16881,Q9HBM6,Q15369,Q9H9B1,Q92878,P23193,Q9Y2Q5,P55199,P14635,Q8WX92,Q07812,O14757,P40938,P42771,P61981,P42345,Q9NVI1,Q9HCE1,Q13794,O43819,P35269,O15514,P54619,P24941,P49959,P19387,P43246 48 +G0 and early g1 0.592656758944133 0.9099246827797034 0.3628622316454981 1.0 0.6789356432982984 6 Q13547,Q5TKA1 2 +Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.4013370024805645 0.9027707176690823 0.3666475952758601 1.0 0.6841413405694572 20 P41440 1 +Cd28 dependent pi3k akt signaling 0.524399615167253 0.8900901688154531 0.3734174714384881 1.0 0.6931359766772234 3 P31751 1 +Fcgr3a mediated il10 synthesis 0.5877309896873381 0.8899351823165907 0.3735006912446914 1.0 0.6931359766772234 6 P07948,O43865,P17252,P10644 4 +Recycling pathway of l1 0.4107826044962909 0.8793340918118999 0.3792201563177557 1.0 0.7020704760554187 17 Q9BUF5,P50570,O95782,Q96CW1,P51812,P63010,O94973 7 +Trafficking of ampa receptors 0.5163548273971373 0.879104659808919 0.3793445314170407 1.0 0.7020704760554187 10 O95782,Q96CW1,Q13555,P63010,P17252,O94973 6 +Fgfr2 alternative splicing 0.4097566098695714 0.8729973452900789 0.3826645247032834 1.0 0.7062982566918519 17 P35269,P52597,Q01085,O15514,P19387 5 +Resolution of d loop structures 0.5126100611820453 0.8614171410620999 0.3890083387286047 1.0 0.7092129812740651 10 P38398,Q9UQ84,Q96B01,P49959,Q92878 5 +Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.5126100611820453 0.8614171410620999 0.3890083387286047 1.0 0.7092129812740651 10 P38398,Q9UQ84,Q96B01,P49959,Q92878 5 +Fatty acid metabolism 0.3119020074977743 0.858084975011014 0.3908455432676734 1.0 0.710817761356142 66 P11310,P33121,O43772,O15254,A8MXV4,Q53GQ0 6 +Dual incision in gg ner 0.3908168971764216 0.8570456450882286 0.3914196589909036 1.0 0.7109140011499234 21 P41440 1 +Regulation of tp53 activity through phosphorylation 0.3563898872508011 0.8545177719165014 0.3928181666571464 1.0 0.7115590694825336 33 P40938,P67870,Q92804,P38398,P49959,Q13131,P54619,Q9UQ84,P24941,Q9HBM6,O14757,Q9ULW0,Q99728,Q00535,Q92878 15 +Ctla4 inhibitory signaling 0.577955759987151 0.8504914930112496 0.3950518880696982 1.0 0.7137096361947927 6 P30153,P07948,P31751,P30154 4 +Gap filling dna repair synthesis and ligation in gg ner 0.4019367029964381 0.8483267673808186 0.3962560144176947 1.0 0.714741795322158 18 P40938,P18887,P49005,Q9NR33,P41440 5 +Er quality control compartment erqc 0.5793313184205617 0.8466410594781535 0.3971952205675921 1.0 0.714741795322158 4 Q9UBV2,Q9NYU2 2 +Death receptor signalling 0.4163870565762568 0.841970979855372 0.3998041975412296 1.0 0.7183347292003462 16 Q9NQC3,O95429,Q13547,P61586 4 +Rna polymerase iii transcription 0.5080328841315346 0.8398918607881358 0.4009690215922019 1.0 0.7183347292003462 10 P62875,Q9Y5Q9,O15160,O14802,Q9Y5Q8,Q9UKN8 6 +Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.5074152115555823 0.8369953734376435 0.4025951686335423 1.0 0.7183347292003462 10 P14635,O14757 2 +Defective cftr causes cystic fibrosis 0.3360413729152018 0.8337082268842998 0.4044454210585284 1.0 0.7183347292003462 42 Q9UBV2,P28074,P49721 3 +Sars cov infections 0.3149283482437266 0.8336854417820242 0.4044582639485821 1.0 0.7183347292003462 56 Q99720,P26572,O95782,Q13724,P78362,Q13547,Q16706,Q14145,P63010 9 +Citric acid cycle tca cycle 0.3900376470181602 0.8287953329608825 0.4072202295638276 1.0 0.7222996009428619 20 Q13423,Q9P2R7,Q02218,P48735 4 +Regulation of tp53 expression and degradation 0.5239002284838148 0.8191908682644263 0.4126775241035554 1.0 0.7310287569834409 9 P42771,P42345,P31751,P30154,P24941 5 +Transcriptional regulation by mecp2 0.4222988403829952 0.8119307505165989 0.4168313684020073 1.0 0.7364740757776398 15 Q14739,Q13451,O75376,Q9BZK7,Q13555,Q13547 6 +Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.5686465433300919 0.8046482611071758 0.4210226840186108 1.0 0.7409381747246062 4 P30153,P17252,P30154 3 +Diseases associated with n glycosylation of proteins 0.519637826842793 0.800209787007966 0.4235892603185371 1.0 0.7426423535661756 9 Q13724,Q9BT22,Q96AA3,Q9NP73 4 +Mitotic metaphase and anaphase 0.2776499345481562 0.7929977826379943 0.4277791146672334 1.0 0.7471976757745985 133 Q8NFH4,Q9UJX2,P60900,Q96EE3,P42166,Q15008,P28072,Q03188,Q9UL46,Q6IPU0,P42167,Q92674,P43034,Q9UJX3,P30154,Q9H1A4,Q96IY1,Q99436,Q8NC56,P49721,P50402,P28074,P14635,O60566,O43684,Q9NQS7,Q9UJX4,Q15691,P25787,P28070,Q16763,Q8NFH5,Q92973,Q8N3U4,Q14739,Q8NFH3,Q9Y6G9,P20618,Q2NKX8,Q53HL2,O60216,O43264,P50748,P46060,Q96FF9,O75694,O00231,Q12769 48 +Activation of ampk downstream of nmdars 0.5619428761139387 0.7820629884199695 0.4341775567515851 1.0 0.7553803410831148 5 Q13131,P54619,Q9BUF5 3 +Notch1 intracellular domain regulates transcription 0.5152856527785029 0.7809296344654592 0.4348438813928013 1.0 0.7555758652481286 9 O75376,Q9BZK7,Q13616 3 +Rna polymerase iii transcription initiation from type 1 promoter 0.5129651112202364 0.7706932327279217 0.4408887840684796 1.0 0.763162819123612 9 P62875,Q9Y5Q9,O15160,O14802,Q9Y5Q8,Q9UKN8 6 +Cd209 dc sign signaling 0.4962809284619054 0.7664364914705628 0.4434166268138353 1.0 0.7655952898405967 3 P17252 1 +Resolution of abasic sites ap sites 0.3632091394908596 0.7529640312214155 0.4514715286200066 1.0 0.7760938349589852 24 P29372,P18887,P49005,Q9NR33,P41440 5 +Sema4d induced cell migration and growth cone collapse 0.5550146056475215 0.7517170089597602 0.452221259479292 1.0 0.7760938349589852 4 P35579,P35580,P61586 3 +Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.3132777155714123 0.7498741853148496 0.45333048335118 1.0 0.7768125367977505 49 O15372,Q9Y262,P60228,P23396,P08708,O15371,P46783,O75822,P62841,P23588,P62263,P05198 12 +Sars cov 1 infection 0.471734325248123 0.7466039014576836 0.4553026926893673 1.0 0.7782366827422268 11 P26572,Q13724 2 +Proton coupled monocarboxylate transport 0.4301005514109585 0.7412976124686584 0.4585130090207603 1.0 0.7817646803803963 2 P35613 1 +Respiratory electron transport 0.3048083941665713 0.7363869932911209 0.4614952178865743 1.0 0.7825018103089191 57 Q9NPL8,P13073,O43676,P09669,Q9GZY4,P03886,O43819,O95168,O96000,Q16718,Q9P0J0 11 +Neuronal system 0.3210629707546754 0.7352297436590542 0.4621995874075346 1.0 0.7825018103089191 44 O95197,P52292,Q13131,P41440,Q9BUF5,P63000,O95782,Q9Y2J2,P51812,Q9HCM4,P63096,P11171,P80404,P08754,O94973,P07196,Q96CW1,P54619,Q13555,P63010,P17252,Q9UM54 22 +Er to golgi anterograde transport 0.2994203323598715 0.733810606989823 0.4630641750255031 1.0 0.7825018103089191 67 Q12907,Q5JRA6,Q14746,Q9UP83,O14653,Q12955,O95249,P62820,P24390,O75396,Q96PC5,Q9UJW0,P83436,O75935,Q9Y3B3,O94979 16 +Ire1alpha activates chaperones 0.3579172211416204 0.7312010860081032 0.4646563369297012 1.0 0.7825018103089191 25 O94979,O14653,Q13217,Q9NWM8,P35611,P51858,Q9Y5M8,O43731 8 +Synthesis of very long chain fatty acyl coas 0.5038588437320686 0.7308368862734527 0.464878790121257 1.0 0.7825018103089191 9 Q9UKU0,Q53GQ0,P33121 3 +Ub specific processing proteases 0.299808557338262 0.7302021787377636 0.4652666109940333 1.0 0.7825018103089191 66 P45974,P28074,Q9HAW4,O00231,P20618,Q9Y3E5,Q86UV5,Q15008,Q99436,P28070,Q14145,P49721,Q9UL46,Q9HBM6,Q96K76 15 +Metalloprotease dubs 0.5491723466407055 0.7292814393551312 0.4658295234390339 1.0 0.7825018103089191 4 P38398,Q99728,O00487 3 +Transcription coupled nucleotide excision repair tc ner 0.319725542837448 0.7237263674551275 0.4692337421019226 1.0 0.7841981917675669 44 P40938,P23193,P62487,P55199,P18887,P49005,O15514,Q9NR33,P19387,P56282,P41440,Q93009,Q13098,Q9BT78 14 +Transport of inorganic cations anions and amino acids oligopeptides 0.4826999815825874 0.7229567421877628 0.4697064609752963 1.0 0.7841981917675669 10 Q15758,Q70HW3 2 +Synthesis of pa 0.5015111364950527 0.7206471209868541 0.4711266543695342 1.0 0.7852731899785068 9 Q9NPH0 1 +Fcgamma receptor fcgr dependent phagocytosis 0.3457762420057895 0.7200254240070575 0.4715093420765375 1.0 0.7852731899785068 29 Q9UQB8 1 +Rac3 gtpase cycle 0.342061384253833 0.715269949821556 0.4744422532481296 1.0 0.7882329274426904 31 Q15758,Q9UQB8,Q96RT1 3 +Hdr through single strand annealing ssa 0.4146368254234524 0.7134663129746692 0.4755572514189514 1.0 0.7891241982183087 14 P40938,P38398,Q9UQ84,P49959,Q99728,Q92878 6 +Signaling by wnt in cancer 0.5289810170419355 0.7033413393453719 0.4818430540360339 1.0 0.7944415186541354 7 P56545,P48729,P30154 3 +Ros and rns production in phagocytes 0.4971328951352831 0.7017441671179432 0.4828387235808491 1.0 0.7944415186541354 9 Q9Y5K8,Q9Y487 2 +Signaling by insulin receptor 0.4016252334018252 0.6967378120185886 0.4859668907314294 1.0 0.7971399704457115 15 Q9Y5K8,Q9Y487,Q93050,P31751 4 +Beta catenin phosphorylation cascade 0.5383486380253435 0.6908967114412492 0.4896304529134245 1.0 0.7998274703879175 5 P30153,P48729,P30154 3 +Disassembly of the destruction complex and recruitment of axin to the membrane 0.5383486380253435 0.6908967114412492 0.4896304529134245 1.0 0.7998274703879175 5 P30153,P48729,P30154 3 +Signaling by ctnnb1 phospho site mutants 0.5383486380253435 0.6908967114412492 0.4896304529134245 1.0 0.7998274703879175 5 P30153,P48729,P30154 3 +Miscellaneous transport and binding events 0.536482303427214 0.6874278467051438 0.4918131546446 1.0 0.8021365752549557 6 Q9UEY8,Q8TDW0 2 +Recruitment of mitotic centrosome proteins and complexes 0.3485641935408052 0.6830538271748947 0.4945728301698926 1.0 0.8030548521217009 26 P61981,P53350,Q14203,Q68CZ6,P07437,Q9H6D7,Q15691,Q13561,Q96CW5,P17252,O75935,P43034 12 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3076050788343006 0.6819888060697961 0.4952460290799239 1.0 0.8030548521217009 48 Q9UJX3,P28074,Q9H1A4,P20618,P49721,P28070,Q16763 7 +Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.4913660991391171 0.6770546347652188 0.4983712905615183 1.0 0.8041585627207448 9 Q96PU5,O75376,P50750 3 +Wnt5a dependent internalization of fzd2 fzd5 and ror2 0.5221904432803852 0.6764311149077548 0.4987669677872068 1.0 0.8041585627207448 7 O95782,Q96CW1,O94973,P63010 4 +Ca dependent events 0.5329404800121157 0.6739000646491173 0.5003748510235215 1.0 0.8057984613885282 6 P52292,P17252,Q13555 3 +Trafficking of glur2 containing ampa receptors 0.5070807008395285 0.6663376149588014 0.5051953279741477 1.0 0.8118135516392269 8 O95782,Q96CW1,O94973,P63010 4 +Perk regulates gene expression 0.405491380398079 0.6652434683348191 0.505894782020176 1.0 0.8118135516392269 14 Q96B26,Q9NQT5,Q15024,Q13868,Q92945,P05198 6 +The role of nef in hiv 1 replication and disease pathogenesis 0.4384480573945275 0.6652422803942312 0.5058955417106619 1.0 0.8118135516392269 12 P04439,P63000,O95782,Q96CW1,P63010 5 +Polo like kinase mediated events 0.5278687704927079 0.648946950220785 0.5163726662796919 1.0 0.825711977497655 4 P14635 1 +Insulin receptor recycling 0.4637505753437836 0.6385072413569233 0.5231435417623018 1.0 0.8304976431595396 10 Q9Y5K8,Q9Y487 2 +Ptk6 regulates rho gtpases ras gtpase and map kinases 0.5247549562761555 0.637420700025991 0.5238508485096935 1.0 0.8304976431595396 4 P61586 1 +N glycan trimming in the er and calnexin calreticulin cycle 0.3901460145731906 0.6349139883162295 0.5254845133593904 1.0 0.8304976431595396 15 Q9UBV2,Q9NYU2 2 +Aurka activation by tpx2 0.3412796356027072 0.6344293662625257 0.5258006497982577 1.0 0.8304976431595396 26 P61981,P53350,Q14203,O75935,Q68CZ6,P07437,Q9H6D7,Q15691,Q13561,P17252,Q9ULW0,P43034 12 +Signaling by fgfr 0.35868312037329 0.6320725243068139 0.5273394879694695 1.0 0.8304976431595396 20 P52597,P35269,Q01085,O15514,P19387 5 +Signaling by fgfr2 0.3586831203732898 0.6320725243068123 0.5273394879694706 1.0 0.8304976431595396 20 P52597,P35269,Q01085,O15514,P19387 5 +Tp53 regulates transcription of cell death genes 0.5219050369662207 0.6269240926299495 0.5307089936791654 1.0 0.8320541004349213 4 Q13794 1 +Cdc42 gtpase cycle 0.3350409851467073 0.6254698135219202 0.5316627544543073 1.0 0.8320943749258141 28 Q14739,Q14344,Q9Y4F1,Q96N67,P42166,Q9UQB8,Q13576 7 +Signaling by nuclear receptors 0.2914090351531853 0.6247549633567785 0.5321318933356067 1.0 0.8320943749258141 62 Q13451,Q8NB78,P62487,P31751,O75376,P50416,Q86X55,Q9BZK7,P35269,O43815,O15514,Q13547,P50750,P19387,Q8N3U4 15 +Negative regulation of mapk pathway 0.4965970294113619 0.6240956027725899 0.5325648015470936 1.0 0.8320943749258141 8 Q99956 1 +Dna double strand break repair 0.2930444625987772 0.6217327889852003 0.5341175874105217 1.0 0.8334527091362495 55 P40938,Q9UNS1,P52292,P18887,P38398,Q9HAW4,P49005,P49959,Q9NR33,Q9UQ84,O14757,Q96B01,P24941,Q9NY27,P41440,O96028 16 +Maturation of sars cov 2 spike protein 0.4246599757403995 0.6002599783210896 0.5483329866691211 1.0 0.8457143206034978 12 P26572,Q13724,P04843,Q16706,P39656 5 +Mitotic spindle checkpoint 0.2903044412763026 0.5970153534924959 0.5504971299428787 1.0 0.8474921955328291 55 Q8NFH4,Q9UJX2,Q96EE3,Q03188,Q6IPU0,Q92674,Q9UJX3,P30154,Q9H1A4,Q96IY1,O60566,O43684,Q9NQS7,Q9UJX4,Q15691,Q16763,Q8NFH3,Q9Y6G9,Q2NKX8,Q53HL2,O43264,P50748,P46060 23 +Cargo recognition for clathrin mediated endocytosis 0.3274037810234512 0.5925779461070528 0.553463642007205 1.0 0.8510985430640672 29 P51809,P20645,O95782,Q96CW1,Q96D71,Q13492,P63010,Q8NC96,Q13098,Q9BT78 10 +Abc transporter disorders 0.3054171829779081 0.5916060262998911 0.554114437506628 1.0 0.8511397440980187 43 Q9UBV2,P28074,P49721 3 +Pi metabolism 0.3608350719685821 0.5848810258886032 0.5586277175822589 1.0 0.8561440525642711 17 Q8IY17,Q9C0I1 2 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.5088456995804912 0.581319369907916 0.56102522825155 1.0 0.858853435841879 5 Q99570,O14654,P31751 3 +Signaling by notch4 0.3052611367317425 0.5685285966265373 0.5696760936680305 1.0 0.8625727150135194 41 Q13616,P28074,P20618,P49721,P28070 5 +Diseases of dna repair 0.3854965955945508 0.5635488059098888 0.5730612358359477 1.0 0.8625727150135194 14 P38398,Q9UQ84,Q96B01,P49959,P43246,Q92878 6 +Recruitment of numa to mitotic centrosomes 0.322932989337606 0.5629405258456712 0.5734753831608828 1.0 0.8625727150135194 29 P30153,Q9BUF5,P61981,P53350,Q14203,Q68CZ6,P07437,Q9H6D7,Q15691,Q13561,Q9BVA1,Q96CW5,P17252,O75935,P43034 15 +Butyrate response factor 1 brf1 binds and destabilizes mrna 0.4459115281971511 0.5620144578069377 0.5741061686597988 1.0 0.8625727150135194 10 Q96B26,Q9NQT5 2 +Rna polymerase ii transcription 0.2292650443357835 0.5593024624477383 0.5759553150864949 1.0 0.863300054701076 316 Q8TBX8,Q03164,Q9UQ84,P62487,Q86V81,P25440,Q9BZK7,Q92797,Q99436,P49721,Q659A1,Q9HCL2,P28074,Q16629,Q8WX92,Q9UJX4,O14757,P40938,Q96PU5,P42771,P61981,Q9NVI1,Q9HCE1,O43819,P54619,P24941,O00231,P28070,Q12824,P13073,Q16625,Q15291,Q92804,Q86X55,P00390,Q9ULW0,Q00535,Q9UJX3,P31350,Q9H1A4,P38398,Q8IXH7,Q15648,P50750,Q86U42,P14635,Q6P2C8,Q14739,Q13794,P35269,O15514,O75152,Q9BXW9,P09669,Q9HBM6,P11802,Q9P2I0,Q96SY0,Q96J02,Q16763,O60244,Q71SY5,Q13616,P20618,Q13555,Q6P9B9,O75376,Q96KQ7,Q13547,Q9UL46,Q6PD62,P31751,P30154,Q9Y2X0,Q9H9B1,Q68CP9,Q07812,Q13451,P42345,P49959,P19387,O94913 82 +Abortive elongation of hiv 1 transcript in the absence of tat 0.3642223330861535 0.5493901988803578 0.5827376987915536 1.0 0.8696435679996489 16 P62487,P35269,Q8IXH7,Q8WX92,O15514,P19387 6 +Nuclear events kinase and transcription factor activation 0.4425990821374468 0.548180674420331 0.5835678504707527 1.0 0.8699306535979308 10 P51812,P50570,P30154 3 +Signaling by receptor tyrosine kinases 0.2755269910231913 0.5407186941472064 0.5887014912797897 1.0 0.8756693937902216 106 Q9Y5K8,O75376,P52597,Q01085,Q9UQB8,Q9Y487,Q13547,Q99570,Q7L576,Q00535,Q96RT1,P62487,P50570,P63000,P31751,P30154,O95782,P51812,P61586,O14654,Q93050,Q8WX92,Q96N67,Q96J02,Q07812,O43865,Q96P70,Q96F07,P41240,O14757,P42345,P35269,Q96CW1,O15514,P63010,P19387 36 +Formation of the early elongation complex 0.3506354058258403 0.529507413809758 0.5964535028254878 1.0 0.8814548025263854 17 P62487,P35269,Q8IXH7,Q8WX92,O15514,P19387 6 +Signaling by tgfb family members 0.3473661648925284 0.5268354297684331 0.5983078768584327 1.0 0.8814548025263854 18 Q96PU5,O75376,P61586,P50750 4 +Signaling by tgf beta receptor complex 0.3473661648925284 0.5268354297684331 0.5983078768584327 1.0 0.8814548025263854 18 Q96PU5,O75376,P61586,P50750 4 +Adaptive immune system 0.2579017065313043 0.5262886494033658 0.5986876682160343 1.0 0.8814548025263854 168 Q9UJX2,P61619,Q03519,Q14203,P52888,Q9C0C9,Q9UL46,O75935,P63000,P50570,Q9UJX3,Q9H1A4,P31751,P30154,O95782,Q5KU26,Q99436,O75396,P49721,Q9UJW0,Q9Y385,Q15369,O00161,Q05086,P04439,P49427,Q9NZ08,P28074,P55786,Q13586,Q96J02,O43865,Q9UJX4,Q14145,P28070,P41240,Q16763,O94973,Q03518,Q96PU5,P63010,P42345,Q13616,P52732,Q96CW1,Q9Y6G9,P20618,O00231,Q5T4S7,O94979 50 +Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.4229289704374674 0.5259673400033573 0.5989108993774201 1.0 0.8814548025263854 11 Q13868,Q96B26,Q9NQT5 3 +Signaling by notch1 pest domain mutants in cancer 0.4536161631886137 0.522430745220072 0.6013704540099023 1.0 0.8839108828335203 9 O75376,Q9BZK7,Q13616 3 +Ksrp khsrp binds and destabilizes mrna 0.4060654821292788 0.5162858866721288 0.6056547519269275 1.0 0.8892498187603113 12 Q96B26,Q9NQT5,Q15024,Q13868,Q92945 5 +G beta gamma signalling through pi3kgamma 0.4348803650494971 0.5135933287753972 0.6075363447385431 1.0 0.89105330561653 3 P61586 1 +Dual incision in tc ner 0.3094038659896364 0.5106712352761852 0.6095812857808744 1.0 0.893092238243945 33 P40938,P23193,P62487,P49005,O15514,Q9NR33,P19387,P56282,P41440,Q93009 10 +Cytosolic sulfonation of small molecules 0.4847573367106492 0.4953988603730291 0.6203185990099134 1.0 0.9068752079844822 4 O43252 1 +Cell extracellular matrix interactions 0.4826955538871676 0.4913485298052596 0.6231799612757363 1.0 0.9100829413063216 6 Q13418 1 +Signaling by notch1 0.4138191402716794 0.487806279334239 0.6256870632239062 1.0 0.9123215663490132 11 O75376,Q9BZK7,Q96J02,Q13616 4 +Oncogene induced senescence 0.4802697555077851 0.4812833539928075 0.6303151261144204 1.0 0.9145641568004904 5 P42771,P11802 2 +Atf4 activates genes in response to endoplasmic reticulum stress 0.3977363788676304 0.4802436616109016 0.6310541439085082 1.0 0.9145641568004904 12 Q96B26,Q9NQT5,Q15024,Q13868,Q92945 5 +Opioid signalling 0.3505093616423986 0.4796637575373439 0.6314665025890078 1.0 0.9145641568004904 16 P63096,P30154,P52292,P10644,P08754,P04899,O43865,Q13555,P17252,Q00535 10 +Abc family proteins mediated transport 0.2762913028889238 0.4778961391576818 0.6327241294732093 1.0 0.9152022402984704 53 Q9UBV2,P28070,P28074,P49721 4 +Apoptotic factor mediated response 0.4770232491541331 0.4703697838262966 0.6380908482326766 1.0 0.9206601536515714 5 Q07812 1 +Signaling by ntrks 0.3103423841604317 0.4680061257859708 0.6397802090341909 1.0 0.921499688619468 28 P63000,P50570,P30154,O95782,Q96CW1,Q8WX92,Q07812,P51812,P63010,O94973,P61586,Q00535 12 +Activation of rac1 0.4743495580101918 0.4605899799593487 0.6450928018251929 1.0 0.9271934475127114 4 O94813 1 +Processing of dna double strand break ends 0.3108994839755506 0.4581954308494179 0.646812042250406 1.0 0.9277093855200356 27 P40938,Q9UNS1,Q9HAW4,P49959,Q9UQ84,P24941,Q9NY27,O14757,O96028 9 +Foxo mediated transcription 0.4193110176683704 0.4546985762256118 0.6493261053170198 1.0 0.930336982828167 10 Q13547,P31751 2 +Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.4035442730498467 0.4461844836471133 0.6554639901610291 1.0 0.936181028879208 11 O95782,Q96CW1,P04439,P63010 4 +Gap junction degradation 0.4684740837119919 0.4421196163569042 0.6584026500826816 1.0 0.9370777896584972 5 Q96CW1,Q00610,P50570 3 +Collagen biosynthesis and modifying enzymes 0.4158743948086241 0.4415154445792819 0.6588398829050579 1.0 0.9370777896584972 10 Q32P28 1 +Rho gtpase effectors 0.2680818291724514 0.4395198008257875 0.6602849377956423 1.0 0.9381548491179752 101 Q8NFH4,Q96EE3,Q9UQB8,Q03188,Q99570,Q6IPU0,Q7L576,Q92674,P43034,P63000,P62993,P30154,Q96IY1,P61586,O15145,O60566,O43684,Q9NQS7,Q15691,Q96F07,P35080,Q13576,Q8NFH3,P61981,Q9Y6G9,Q2NKX8,Q53HL2,O43264,P50748,P46060,P17252,Q12769 32 +Wnt5a dependent internalization of fzd4 0.4309927138788498 0.4369958985832173 0.6621143224836952 1.0 0.9388813181386988 9 O95782,Q96CW1,P63010,P17252,O94973 5 +Activation of gene expression by srebf srebp 0.3261074991004186 0.4308353219720067 0.6665881144525785 1.0 0.9411289797975912 19 Q86X55,Q9BZK7,P48449,P14324,Q9HCL2,O75845 6 +Tcf dependent signaling in response to wnt 0.2701090195161329 0.4307677443325695 0.6666372553100985 1.0 0.9411289797975912 59 Q15291,P67870,P60900,Q15008,Q13547,P28072,Q9UL46,Q92530,P31751,P30154,Q9UBL3,Q99436,Q9HCK8,P49721,P51665,P28074,P25787,O14980,P48729,O43242,P25788,P30153,O00231,P20618,P28070 25 +Irs mediated signalling 0.4633043978705735 0.4247869205609122 0.6709920132189717 1.0 0.94300642768565 4 Q99570,P31751 2 +Anchoring of the basal body to the plasma membrane 0.3051582479604753 0.4145630871180432 0.6784617750216202 1.0 0.9491566378313582 26 P61981,P53350,Q14203,Q68CZ6,P07437,Q9H6D7,Q15691,Q13561,P17252,O75935,P43034 11 +Rhob gtpase cycle 0.3252763744777524 0.4129692793186985 0.679629121642519 1.0 0.9491566378313582 18 P41440 1 +Senescence associated secretory phenotype sasp 0.3194207561978217 0.4128668307917791 0.6797041839460887 1.0 0.9491566378313582 20 P42771,Q9UJX3,Q9H1A4,Q96KQ7,Q9UJX4,P51812,Q16763,Q9H9B1,P11802 9 +Regulation of localization of foxo transcription factors 0.4589296687476286 0.4126571859960832 0.67985779703903 1.0 0.9491566378313582 6 P31751 1 +Netrin 1 signaling 0.4579662162246042 0.4084218217255512 0.6829640153915357 1.0 0.9515453697589936 5 O94813 1 +Regulation of mrna stability by proteins that bind au rich elements 0.2669108597887937 0.4046718378636428 0.6857187456619607 1.0 0.9541610317729102 58 Q96B26,Q9NQT5,P28074,P49721 4 +Darpp 32 events 0.4368854714605043 0.4030112065743021 0.6869399803526377 1.0 0.9541610317729102 8 P17252,P10644,Q00535,P30154 4 +Calnexin calreticulin cycle 0.4203180030200443 0.3989820653938621 0.6899064191502562 1.0 0.954393869899543 9 Q9UBV2,Q9NYU2 2 +The phototransduction cascade 0.3532273759325307 0.3977004424206039 0.690851011269147 1.0 0.9547322992615164 2 P17252 1 +Cilium assembly 0.2653395278224543 0.3951728621538238 0.6927153190892086 1.0 0.9563397725077738 52 Q14203,Q8IYI6,Q10713,Q13561,O75935,Q92538,P43034,Q9BUF5,A0AVF1,P36405,P07437,Q96KP1,Q9H6D7,Q15691,O00471,Q92973,A6NIH7,P30153,P61981,P49368,P53350,Q9NV70,Q68CZ6,P17252 24 +Costimulation by the cd28 family 0.3627546208666485 0.3935326804396035 0.6939260915286478 1.0 0.9567023128539682 13 P42345,P63000,P31751,P30154,P41240 5 +Gastrin creb signalling pathway via pkc and mapk 0.4502210729039394 0.3843528197616617 0.7007169642498394 1.0 0.9631543211784206 5 P51812,P62993 2 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.4159009366263778 0.3837253863667001 0.7011819948168414 1.0 0.9631543211784206 9 P09601 1 +Cytosolic trna aminoacylation 0.3043762246897429 0.3771511448501469 0.7060612846480381 1.0 0.9657264783927229 23 Q9P2J5,Q15046,P26640,Q13155,Q9Y285,P49588,P49591,P54136,Q12904,Q9NSD9,P26639,P14868,P56192,P49589,O43776,P23381,P41250,P41252,P54577,O43324,P07814,P47897 22 +Regulation of tp53 activity through methylation 0.4463943746228878 0.3724561060318794 0.7095532871683363 1.0 0.9659423506944462 4 Q96KQ7,Q9H9B1 2 +Formation of rna pol ii elongation complex 0.2877409565221209 0.3698383752242623 0.711502920076396 1.0 0.9659423506944462 32 Q6PD62,P23193,P62487,P35269,Q8IXH7,Q8WX92,O15514,P19387,P50750,Q15369 10 +P75 ntr receptor mediated signalling 0.3831046447991134 0.3683939711731157 0.7125794921773254 1.0 0.9659423506944462 11 Q14344,P63000,Q9NQC3,Q13547,P61586 5 +Cargo concentration in the er 0.3258352386433773 0.3647977222716069 0.7152624054707917 1.0 0.9659423506944462 16 Q12907,O14653,Q5JRA6,O75396 4 +Myd88 independent tlr4 cascade 0.3554665837217584 0.3644896838437653 0.7154923758856844 1.0 0.9659423506944462 13 P30154,Q13616 2 +Prevention of phagosomal lysosomal fusion 0.3934692524996916 0.3643430379956894 0.7156018654769449 1.0 0.9659423506944462 3 Q9H267 1 +Transferrin endocytosis and recycling 0.3815940100496224 0.36293162717044 0.7166559601934359 1.0 0.9659423506944462 11 Q9Y5K8,Q9Y487 2 +Downregulation of smad2 3 smad4 transcriptional activity 0.4337729961451476 0.3612674330128406 0.7178995367267778 1.0 0.9659423506944462 7 Q96PU5,O75376 2 +Interleukin 17 signaling 0.3810630727101275 0.3610216761222472 0.7180832431115605 1.0 0.9659423506944462 11 P30154,Q13616 2 +Signaling by fgfr2 in disease 0.3677429005298251 0.3600719893968187 0.7187932990637695 1.0 0.9659448866236272 12 P62993,P62487,P35269,O15514,P19387 5 +Interferon alpha beta signaling 0.4326205662962394 0.3577201203885292 0.720552774280355 1.0 0.9662745378066536 7 P61221,P04439,P10321 3 +Pyruvate metabolism and citric acid tca cycle 0.277064746425537 0.3554919511321989 0.7222210737424279 1.0 0.9662745378066536 37 Q9P2R7,Q9H9P8,P48735,Q13423,Q02218 5 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.323215508904651 0.3535094115628825 0.7237065742702831 1.0 0.9662745378066536 16 Q5JRA6,O43852,Q15293 3 +Infectious disease 0.2180932199007712 0.3512319856143008 0.7254143157727371 1.0 0.9662745378066536 323 Q8NFH4,Q99720,Q9UQB8,O00410,Q99570,Q9BRG1,P62487,P23396,Q9BZK7,Q99436,P14373,P49721,P09601,O15145,P04439,P83916,P28074,Q8WX92,Q96F07,P12235,Q96PU5,Q96CW1,O00231,P28070,Q92804,P52292,Q7L576,P63000,Q8IXH7,Q9H267,P50750,Q9Y3E5,Q15369,Q86U42,P23193,P55199,P62841,O94973,Q8NFH3,P35269,Q9Y6G9,O15514,P18621,P19525,O75694,Q96EE3,P08708,P62244,Q15008,Q15185,P62993,P62875,P46783,Q16881,Q9HBM6,Q13724,P08754,P04843,Q14145,P25787,P39656,P46776,P48729,P20339,P20618,Q16706,P46060,P17252,P62263,Q12769,P60900,P54709,O75376,Q13547,P83731,P28072,P62750,Q9UL46,P61254,O95782,P78362,P26572,Q13217,O43865,Q8NFH5,Q9Y2Z0,Q9Y3U8,P63010,P19387 89 +Tp53 regulates transcription of cell cycle genes 0.3497899904460983 0.3426588191936677 0.7318551465797121 1.0 0.9720062511535806 13 P14635,Q86X55,Q07812 3 +Hiv infection 0.2385780288544207 0.3383154441112194 0.7351254864771739 1.0 0.9735059840338496 132 Q8NFH4,Q92804,Q96EE3,Q9UL46,P62487,P63000,O95782,Q8IXH7,Q99436,P49721,P50750,Q9HBM6,Q15369,P23193,P04439,P28074,P55199,Q8WX92,P28070,Q8NFH5,P12235,O94973,Q96PU5,Q8NFH3,P63010,P35269,Q96CW1,P20618,O15514,O00231,P19387 31 +Gap junction trafficking and regulation 0.4145702823259709 0.331362819268916 0.7403704458735474 1.0 0.9773376556959888 8 Q9BUF5,Q00610,P50570,Q96CW1,Q9UM54 5 +Rmts methylate histone arginines 0.2960554303978641 0.3235875805974383 0.7462502917504823 1.0 0.9796479076151356 22 Q86X55,P11802,Q12824 3 +Sensing of dna double strand breaks 0.42756887589594 0.318096455360815 0.7504117723143697 1.0 0.9796479076151356 4 P52292,P49959 2 +Signaling by fgfr2 iiia tm 0.3684042854590442 0.3170536758644141 0.7512028741206456 1.0 0.9796479076151356 11 P35269,P19387,O15514 3 +Fgfr2 mutant receptor activation 0.3684042854590442 0.3170536758644141 0.7512028741206456 1.0 0.9796479076151356 11 P35269,P19387,O15514 3 +Vegfr2 mediated cell proliferation 0.3787501769104318 0.3169850839639133 0.7512549203558885 1.0 0.9796479076151356 3 O43865 1 +Signaling by interleukins 0.2536323649733492 0.307217595369708 0.7586777535509339 1.0 0.9864980513283832 97 Q13126,P28074,P51809,Q13616,P52597,P20618,P30154,P51812,P49721,P28070,Q9UL46,P09601,P78417 13 +Diseases of signal transduction by growth factor receptors and second messengers 0.2352648574395645 0.3053876346324959 0.7600709384027173 1.0 0.987350990317463 134 Q99956,O75376,Q13547,Q9UL46,Q6WCQ1,Q96RT1,P62487,P31751,P30154,Q9BZK7,Q9UBV2,P49721,P28074,O95429,P51114,P42345,Q13616,P35269,P20618,O43815,O15514,Q13555,O43252,P28070,P19387,O94979 26 +Cytosolic sensors of pathogen associated dna 0.3251851078779771 0.3006253493649338 0.7637001991378634 1.0 0.987350990317463 14 P78527,P62875,O15160,O14802,P49959 5 +Fceri mediated mapk activation 0.4179806461422543 0.2919326043254112 0.7703381541333927 1.0 0.987350990317463 5 P62993,P63000 2 +Base excision repair 0.2771846663317629 0.2918191053926635 0.7704249367492366 1.0 0.987350990317463 28 P29372,P18887,P49005,Q9NR33,P41440 5 +Mrna capping 0.3227588061550376 0.2918017547873738 0.7704382034789594 1.0 0.987350990317463 14 P35269,P19387,O15514 3 +Phospholipid metabolism 0.2527934854453104 0.2917766610622738 0.7704573909208199 1.0 0.987350990317463 50 Q9C0I1,Q9NPH0,Q8WWI5,Q13614,Q8IY17 5 +Regulation of plk1 activity at g2 m transition 0.2726778012526531 0.2834986270282452 0.7767946339847149 1.0 0.9911579801264278 30 P61981,Q13616,P14635,Q14203,Q68CZ6,Q9H6D7,Q15691,Q13561,P17252,O75935 10 +G alpha 12 13 signalling events 0.4120964981994686 0.2767928583107749 0.7819391652526511 1.0 0.9949300572804256 4 P61586 1 +Activation of bad and translocation to mitochondria 0.3942296163985139 0.2725196521067503 0.7852224826981709 1.0 0.9981765763283366 8 P31751 1 +Anti inflammatory response favouring leishmania parasite infection 0.3377974712251005 0.2579212923398191 0.7964676517696139 1.0 1.0 12 P63096,P10644,P07948,P08754,P04899,O43865,Q9Y3E5,P17252,P35579 9 +Cyclin a b1 b2 associated events during g2 m transition 0.3720274443053443 0.2491669456863563 0.8032316467345222 1.0 1.0 9 P30154,P53350,P14635,P24941,O14980 5 +Reduction of cytosolic ca levels 0.3998701720220771 0.2464628163012479 0.8053239850678195 1.0 1.0 4 P16615,P23634,P20020 3 +Signaling by wnt 0.2456392804612689 0.2464072460884666 0.8053669975712676 1.0 1.0 82 Q15291,P67870,P60900,Q15008,Q13547,P28072,Q9UL46,Q9UBQ0,P63000,P31751,P30154,O95782,Q9UBL3,Q99436,Q9HCK8,P49721,P61586,Q00610,P28074,P25787,P28070,P48729,O94973,O43242,P63010,Q9HCE1,Q13616,Q96CW1,P20618,O00231,P17252,Q96QK1 32 +Rac2 gtpase cycle 0.2607567212049113 0.2426898325401213 0.808245684480007 1.0 1.0 33 Q13505,Q96RT1 2 +Negative regulation of fgfr3 signaling 0.3530012279228858 0.2426387396422275 0.8082852679328116 1.0 1.0 3 P62993 1 +Negative regulation of fgfr1 signaling 0.3530012279228858 0.2426387396422275 0.8082852679328116 1.0 1.0 3 P62993 1 +Negative regulation of fgfr2 signaling 0.3530012279228858 0.2426387396422275 0.8082852679328116 1.0 1.0 3 P62993 1 +Negative regulation of fgfr4 signaling 0.3530012279228858 0.2426387396422275 0.8082852679328116 1.0 1.0 3 P62993 1 +Signaling by fgfr1 0.3530012279228858 0.2426387396422275 0.8082852679328116 1.0 1.0 3 P62993 1 +Signaling by fgfr3 0.3530012279228858 0.2426387396422275 0.8082852679328116 1.0 1.0 3 P62993 1 +Signaling by fgfr4 0.3530012279228858 0.2426387396422275 0.8082852679328116 1.0 1.0 3 P62993 1 +Spry regulation of fgf signaling 0.3530012279228858 0.2426387396422275 0.8082852679328116 1.0 1.0 3 P62993 1 +Insulin receptor signalling cascade 0.3981508679210123 0.2419723673812157 0.8088015747027244 1.0 1.0 5 Q99570,P31751 2 +Mapk targets nuclear events mediated by map kinases 0.3901703229294176 0.2402149131982738 0.8101636530494429 1.0 1.0 7 P30154 1 +Erk mapk targets 0.3901703229294176 0.2402149131982738 0.8101636530494429 1.0 1.0 7 P30154 1 +Regulation of cholesterol biosynthesis by srebp srebf 0.2681476605105761 0.2389513577150256 0.8111433011082143 1.0 1.0 26 Q86X55,Q9BZK7,P48449,P14324,Q9HCL2,O75845 6 +Ion channel transport 0.2601038817541075 0.2357786518807378 0.8136044345145008 1.0 1.0 32 Q9Y5K8,Q96PU5,Q9HD20,Q13555,Q9Y487,Q9C0H2,Q93050 7 +M phase 0.2247848102200669 0.2325694783875036 0.8160957301747493 1.0 1.0 183 Q8NFH4,P67870,Q9UJX2,P60900,Q96EE3,Q14203,P42166,Q15008,Q13561,P28072,Q03188,Q96CW5,Q9NTJ3,Q9UL46,O75935,Q6IPU0,P42167,Q92674,Q9BPX3,P43034,Q9UJX3,P30154,Q9H1A4,Q96IY1,Q99436,Q8NC56,P49721,O60763,P50402,P28074,P14635,O60566,O43684,Q9NQS7,Q9H6D7,Q9UJX4,Q15691,P25787,P28070,Q16763,Q8NFH5,Q92973,Q8N3U4,Q15021,Q14739,P61981,Q8NFH3,Q9Y6G9,P20618,Q2NKX8,Q68CZ6,Q53HL2,O60216,O43264,P50748,P46060,P62820,Q96FF9,O75694,O00231,P17252,Q12769 62 +Auf1 hnrnp d0 binds and destabilizes mrna 0.2510068197356679 0.2295332363499763 0.8184544912138096 1.0 1.0 40 P28074,P49721 2 +Mrna decay by 5 to 3 exoribonuclease 0.3644938852390031 0.2294604480353156 0.8185110584344195 1.0 1.0 9 Q9Y4Y9,P62312 2 +Uptake and function of diphtheria toxin 0.3924050632911454 0.2289896667997239 0.8188769474653652 1.0 1.0 4 P13639,Q16881,P07900 3 +Uptake and actions of bacterial toxins 0.3925324675324771 0.228846264319655 0.818988407060733 1.0 1.0 5 P13639,Q16881,P07900,Q8WUM4 4 +Collagen formation 0.3251926645861964 0.2210167823951688 0.8250793656286131 1.0 1.0 12 Q32P28 1 +Synthesis of pips at the early endosome membrane 0.3880479901161877 0.2187053485526368 0.8268795823068793 1.0 1.0 5 Q9C0I1 1 +Transmission across chemical synapses 0.252260503950616 0.217406854671179 0.827891289696959 1.0 1.0 35 P63096,Q9BUF5,P63000,P10644,P52292,P07196,O95782,P80404,P08754,Q96CW1,Q13131,P54619,Q13555,P51812,P63010,P17252,O94973,Q9UM54 18 +Rho gtpase cycle 0.220859494641928 0.1936515251996657 0.8464487504997185 1.0 1.0 144 Q9P0I2,Q14739,Q96RT1,Q9Y4F1,Q13505,Q96N67,Q9UQB8,Q96HY6,Q96F07,Q15758,P41440,P30519 12 +Rho gtpases activate ktn1 0.3697215909416453 0.1935738969699118 0.8465095387703241 1.0 1.0 7 P61586 1 +Formation of tubulin folding intermediates by cct tric 0.3317073170731651 0.1823427251564301 0.8553137708489402 1.0 1.0 10 Q9BUF5,Q99832,P49368,P50990,P40227,P50991,Q9BVA1,P78371,P17987 9 +Postmitotic nuclear pore complex npc reformation 0.2573898389777681 0.1763567541219442 0.8600136773182663 1.0 1.0 22 Q8NFH4,Q8NFH3,Q8N1F7,Q96EE3,Q8WUM0,P46060,P52948,O75694,Q8NFH5,Q92973,Q12769 11 +Membrane trafficking 0.2143836713267629 0.1753381062218831 0.8608139710979337 1.0 1.0 219 Q9H3P7,Q5JRA6,O94979,P51809,Q6NUQ1,P49257,O60749,Q9NRW7,O95295,O43752,Q6IQ22,O14976,Q8NC96,Q9BRG1,O75935,Q13098,Q9Y3B3,Q92538,Q86YS7,Q9NP72,Q9BT78,P50570,P31751,O14653,Q12955,O95782,O75396,Q9UJW0,P60520,Q15907,O15145,O60476,Q12907,Q14746,P40616,P24390,O00471,Q13492,Q96PC5,P83436,O43731,P61981,Q8N2H4,P20645,Q9UP83,P52732,O95249,Q96CW1,P62820,P54619,Q96D71,Q16706,P63010,Q9NVG8 54 +G2 m dna damage checkpoint 0.2435963134383322 0.1752283878414413 0.8609001791378366 1.0 1.0 32 P40938,P61981,P14635,Q9UQ84,P49959,O14757,O96028 7 +Interleukin 15 signaling 0.284138825819011 0.1747542324826948 0.8612727520246661 1.0 1.0 2 P62993 1 +Vesicle mediated transport 0.2129878932414753 0.1733791575725064 0.8623534068461294 1.0 1.0 226 Q9H3P7,Q5JRA6,O94979,P51809,Q6NUQ1,P49257,O60749,Q9NRW7,O95295,O43752,Q6IQ22,O14976,Q8NC96,Q9BRG1,O75935,Q13098,Q9Y3B3,Q92538,Q86YS7,Q9NP72,Q9BT78,P63000,P50570,P31751,O14653,Q12955,O95782,Q5KU26,O75396,Q9UJW0,P60520,Q15907,O15145,O60476,O00161,Q12907,Q14746,P40616,P24390,O00471,Q13492,Q96PC5,P83436,O43731,P61981,Q8N2H4,P20645,Q9UP83,P52732,O95249,Q96CW1,Q8WTV0,P62820,P54619,Q96D71,Q16706,P63010,Q9NVG8 58 +Toll like receptor 9 tlr9 cascade 0.2835561976331008 0.1720104604932847 0.8634293052890121 1.0 1.0 14 P30154,P51812,Q13616 3 +Formation of tc ner pre incision complex 0.2497744476656246 0.1710191595977548 0.8642087003523904 1.0 1.0 25 P61201,P23193,P62487,P62875,O15514,P19387,Q93009,Q13098,Q9BT78 9 +Cargo trafficking to the periciliary membrane 0.2548548153674641 0.1582697168667449 0.8742442697909019 1.0 1.0 20 O00471,Q10713,A6NIH7 3 +Mapk6 mapk4 signaling 0.2264911719393061 0.1514975528654777 0.8795832410891034 1.0 1.0 46 P28074,P49721 2 +Copi dependent golgi to er retrograde traffic 0.2291718282047151 0.1506134044637601 0.8802806867886159 1.0 1.0 42 Q9BUF5,Q6NUQ1,O43731,P52732,Q9Y678,P62820,O43264,P24390,P49755,O75396,Q8N6T3,Q9Y3B3,Q92538 13 +Clathrin mediated endocytosis 0.2252971580972157 0.1498569178907717 0.8808775023399611 1.0 1.0 47 P63010,P50570,P51809,P20645,O95782,Q96CW1,Q96D71,Q14C86,O14976,Q13492,Q8NC96,Q13098,Q9BT78,O15145 14 +Deactivation of the beta catenin transactivating complex 0.3134653168955595 0.144851944706435 0.8848277687295654 1.0 1.0 10 Q15291,Q13547,P31751 3 +Toll like receptor cascades 0.2524576411756098 0.1444733266067939 0.8851267177464699 1.0 1.0 18 Q99570,P30154,P51812,Q13616 4 +Dap12 signaling 0.3089568164305454 0.143424972660898 0.8859545615273627 1.0 1.0 3 P63000 1 +Signaling by fgfr in disease 0.2480604147553089 0.1407991766591616 0.8880285935170207 1.0 1.0 20 O95429,P62487,P62993,P62875,P35269,O15514,P19387 7 +Negative regulation of the pi3k akt network 0.2904744869063214 0.1394307231992683 0.8891097958704137 1.0 1.0 12 Q8TBX8,P63000,P31751,P30154,O43815 5 +Rho gtpases activate nadph oxidases 0.344106793720158 0.1353883908845589 0.8923048023542366 1.0 1.0 6 Q99570,P63000 2 +Activation of anterior hox genes in hindbrain development during early embryogenesis 0.2467402873320992 0.131403862712037 0.8954558331581517 1.0 1.0 18 Q15291,P62487,P62875,O75376,O15514,Q9UBL3,Q92600,P19387 8 +Interleukin 12 family signaling 0.2282533305192009 0.1300582073742993 0.8965203748878239 1.0 1.0 29 P52597,Q13126,P78417,P51809 4 +Post translational protein modification 0.1965204997493896 0.1300276356262334 0.8965445622284887 1.0 1.0 380 Q8NB78,Q5JRA6,Q96EE3,Q15293,P85037,Q9NP73,Q13547,Q14527,Q6IQ22,Q9NYU2,O60762,Q9UL46,Q9NR45,Q9NP72,O75935,Q9Y3B3,Q9BT78,Q6PD62,O75381,O14653,Q12955,P38435,Q96AA3,Q969Q5,Q9BZG1,Q9UBV2,P14373,P49721,O75396,Q9HBM6,Q9UJW0,Q96K76,P61586,O60476,Q9Y5A7,Q12907,P26572,P28074,Q14746,Q13724,Q13217,P24390,Q14145,Q16763,Q96PC5,Q8NBJ7,Q8N3U4,P83436,Q13616,Q9UP83,O95249,P20618,P34949,Q16706,O43852,P28070,O60725 57 +Biological oxidations 0.2208517612751801 0.1256907387042584 0.8999767331683806 1.0 1.0 41 P30837,Q8TB61,P10620,O43252,O43169,P78417 6 +Sensory processing of sound by outer hair cells of the cochlea 0.2801044666210751 0.1207848881714932 0.9038614199559478 1.0 1.0 12 Q9Y2J2 1 +Intrinsic pathway for apoptosis 0.2401287646931974 0.119789365498244 0.9046500063824912 1.0 1.0 19 P42771,Q07812,P31751,Q13794 4 +Insulin processing 0.2883175137504898 0.1182188325643348 0.9058942683641756 1.0 1.0 11 Q8TAD4,Q9NV70,Q96KP1,Q86YB8,O00471 5 +Copii mediated vesicle transport 0.2252101300993844 0.1164416696506739 0.9073025123775482 1.0 1.0 27 Q12907,O60763,Q9Y6Y8,P49257,O14653,P62820,P49755,O75396,O94979 9 +Piwi interacting rna pirna biogenesis 0.307819509523985 0.1161008985417576 0.9075725766978276 1.0 1.0 9 P19387,O15514 2 +Dap12 interactions 0.3297652381885385 0.1152930460196109 0.9082128500805148 1.0 1.0 4 P62993,P63000 2 +Dna repair 0.2083780263419683 0.1106303320107952 0.9119094936530228 1.0 1.0 107 P52292,Q9UQ84,Q96B01,Q9NY27,P41440,Q13098,Q9BT78,Q9BXW9,P62487,Q9UNS1,P29372,P18887,P38398,P23193,Q6P6C2,P55199,O14757,P40938,Q9NVI1,Q9HAW4,P49005,O15514,Q9NR33,P24941,P49959,P19387,O96028 27 +Nuclear envelope ne reassembly 0.2127932570465465 0.1092156929854282 0.913031413563418 1.0 1.0 44 Q8NFH4,Q96EE3,P42166,Q9Y2U8,P42167,Q9BUF5,Q8NC56,Q8N1F7,P50402,P14635,Q8WUM0,P52948,Q8NFH5,Q92973,P30153,Q14739,Q8NFH3,P46060,Q9BVA1,O75694,Q12769 21 +G protein beta gamma signalling 0.3248918037615254 0.1085540602208337 0.9135561999708948 1.0 1.0 5 P61586 1 +Mrna splicing minor pathway 0.2152045974584414 0.108243437619933 0.9138025891149228 1.0 1.0 35 Q16629,P35269,Q15427 3 +Cellular responses to stimuli 0.1770750380682068 0.1074662983188247 0.914419060496801 1.0 1.0 317 Q8NFH4,P13073,Q9Y5K8,Q96EE3,O75376,Q86X55,Q96KQ7,Q99615,Q9UL46,O75935,P09669,Q9UJX3,Q9H1A4,P23396,O14653,Q9BZK7,Q8TED1,Q9NWM8,Q13868,P46783,Q86WX3,P35611,P51812,Q92945,P49721,Q9UJW0,P09601,Q9H9B1,P11802,P30519,Q9NQT5,P28074,Q13217,P51858,P62841,Q14145,Q16763,Q8NFH5,O95429,Q13451,Q96B26,P42345,Q13616,P54652,O43819,P20618,Q13555,Q9Y3U8,P28070,P49959,O95816,P62263,O94979 53 +Mapk family signaling cascades 0.2135086952582998 0.1073686251270358 0.9144965441137388 1.0 1.0 77 P07196,Q99956,P28074,P20618,Q13555,P49721,Q96P70,P28070,Q9UL46,O60725 10 +Golgi to er retrograde transport 0.2104290851744752 0.1072435832467573 0.9145957403497496 1.0 1.0 62 Q6NUQ1,Q15102,Q14203,Q13561,Q9NP72,O75935,Q9Y3B3,Q92538,P43034,Q9BUF5,O75396,Q9UJW0,Q8N6T3,P24390,P49755,O43731,P52732,Q9Y6G9,Q9Y678,P62820,O43264 21 +Cd28 co stimulation 0.3002595234015711 0.1055955647470279 0.9159032438965288 1.0 1.0 9 P42345,P63000,P31751 3 +Toll like receptor tlr1 tlr2 cascade 0.2604313436684679 0.1053373282493063 0.9161081440658944 1.0 1.0 13 P30154,Q13616 2 +Establishment of sister chromatid cohesion 0.288249325035243 0.1044316289935839 0.9168268235945628 1.0 1.0 10 Q8WVM7,Q29RF7,Q96FF9,O60216,Q8N3U4 5 +Neddylation 0.2092608621725947 0.0999249517890592 0.9204039068264926 1.0 1.0 71 Q9Y5A7,P28074,Q13616,P20618,P49721,Q14145,P28070,Q9UL46 8 +Signaling by robo receptors 0.1861684434832204 0.0996096863638471 0.9206542034698876 1.0 1.0 132 P60900,P08708,P62244,Q15008,P83731,P28072,O94813,P62750,Q9UL46,P63000,P23396,P46783,Q99436,P49721,Q15369,P61586,Q9Y5S9,P28074,P62841,P35080,P25787,P46776,O00231,P20618,P18621,Q9Y3U8,P28070,P17252,P62263 29 +Host interactions of hiv factors 0.2096468640363197 0.0988706917848378 0.9212409394278812 1.0 1.0 93 Q8NFH4,P60900,Q96EE3,Q15008,P28072,Q92530,Q9UL46,Q9BXS5,P63000,O95782,Q99436,P49721,P50750,P51665,Q15369,Q8N1F7,P04439,P28074,Q8WUM0,P52948,P25787,O14980,P28070,P12235,Q8NFH5,O94973,O43242,P25788,Q8NFH3,P63010,Q10567,Q96CW1,P20618,Q99567,P46060,O75694,O00231,Q12769 38 +Deadenylation of mrna 0.2707584276398619 0.0936126134896366 0.9254168895020024 1.0 1.0 11 Q92600,O95453,P06730,P23588 4 +Signaling by scf kit 0.2899316890021293 0.0928854962592322 0.9259945282380996 1.0 1.0 9 P62993,P63000,P07947,P07948,P17252,O14757 6 +Signaling by rho gtpases miro gtpases and rhobtb3 0.1725211641313876 0.0927112948937822 0.9261329236342446 1.0 1.0 232 Q8NFH4,Q96EE3,Q13505,P49257,Q9UH62,P42166,Q9UQB8,A4D1P6,Q96HY6,Q99570,Q15758,P41440,Q16718,Q6IPU0,Q13098,Q7L576,Q92674,Q9BT78,Q9P0I2,Q14344,Q96RT1,P63000,P30154,Q96IY1,Q9NNW5,P38159,O00161,P61586,O15145,P30519,Q9Y4F1,P50402,Q03001,O60566,Q96N67,Q9NQS7,Q15691,Q13492,Q96F07,P41240,Q13576,Q9BX68,Q14739,P61981,Q8IXI1,Q9UEY8,Q8NFH3,Q2NKX8,P50748 49 +Lipophagy 0.3099642973060768 0.0915300952122458 0.9270713940745112 1.0 1.0 4 P54619,P54646,O60664 3 +Platelet homeostasis 0.2776611539220713 0.0911936369735437 0.9273387308470238 1.0 1.0 10 Q13586 1 +Condensation of prometaphase chromosomes 0.2775041580639752 0.0910130089616485 0.9274822543021012 1.0 1.0 10 Q9NTJ3,P14635,Q15021,Q9BPX3 4 +Visual phototransduction 0.3077922077922154 0.089025935424494 0.9290612984645544 1.0 1.0 5 Q6NUM9,Q8TC12,P30419,P17252 4 +Regulation of expression of slits and robos 0.181607129094637 0.0881739187358541 0.9297384463951516 1.0 1.0 120 P60900,P08708,P62244,Q15008,P83731,P28072,O94813,P62750,Q9UL46,P23396,P46783,Q99436,P49721,Q15369,Q9Y5S9,P28074,P62841,P28070,P25787,P46776,P20618,P18621,Q9Y3U8,O00231,P62263 25 +Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.2078952332435782 0.0858590278430756 0.9315784822326498 1.0 1.0 26 Q13451,P54652,Q14203,Q9Y6G9,Q15185,Q13561,Q9UJW0,O75935,P31689 9 +Cytokine signaling in immune system 0.1517393567003557 0.0851250524731348 0.9321619735974932 1.0 1.0 158 Q8NFH4,Q9H3K6,P60900,Q96EE3,P51809,P52292,P52597,Q15008,Q07820,P28072,Q9UL46,P06730,Q13126,P62993,P31751,P29372,P30154,P61221,Q99436,P51812,P49721,Q15369,P09601,P78417,P04439,P28074,Q13277,P25787,P41240,P28070,Q8NFH5,Q8NFH3,Q13616,P20618,Q13555,P19525,O15344,O75694,O00231,P17252,P46109,Q12769 42 +Interconversion of nucleotide di and triphosphates 0.2250457690001528 0.0843695211630253 0.9327626394512676 1.0 1.0 16 P31350,P17812,P00390,Q9H773,Q16881 5 +Nucleotide excision repair 0.196680625492314 0.0835371941023247 0.9334244041157028 1.0 1.0 54 P40938,P23193,P62487,P55199,P18887,P49005,O15514,Q9NR33,P19387,P56282,P41440,Q93009,Q13098,Q9BT78 14 +Cooperation of prefoldin and tric cct in actin and tubulin folding 0.2334744382937156 0.0827777133759835 0.9340282904472204 1.0 1.0 14 Q9BUF5,Q99832,P61758,P49368,P50990,P40227,Q9UHV9,O60925,P48643,P50991,Q9BVA1,P78371,P17987 13 +Influenza infection 0.1383237008134551 0.0814736704321521 0.935065263203974 1.0 1.0 125 Q8NFH4,Q96EE3,P52292,P08708,P62244,O00410,P83731,P62750,P61254,P62487,P62875,P23396,P46783,Q86U42,Q00610,Q13217,Q8WUM0,P62841,Q8NFH5,P46776,Q8NFH3,P27635,P62266,P35269,O15514,P18621,P19525,Q9Y3U8,O75694,P19387,P62263,Q12769 32 +Pi3k akt signaling in cancer 0.288180471121042 0.080492031567484 0.9358459335606232 1.0 1.0 8 P42345,O43815,P63000,P31751 4 +Inhibition of replication initiation of damaged dna by rb1 e2f1 0.294949476937151 0.0770151623311305 0.9386114829970194 1.0 1.0 6 P30154,Q14181 2 +Intracellular signaling by second messengers 0.2004638377339596 0.0768341623954633 0.9387554733954796 1.0 1.0 82 Q8TBX8,P42345,P31751,P28074,Q9HCE1,O00231,P52292,P20618,P30154,O43815,O43865,Q13555,Q13547,Q99436,P28070,P14373,P49721,Q9UL46 18 +Sealing of the nuclear envelope ne by escrt iii 0.2884990253411319 0.075715154956222 0.9396457186931508 1.0 1.0 7 Q9BUF5,O43633,Q96FZ7,Q8NC56,Q9BVA1,Q8WUX9 6 +Endosomal sorting complex required for transport escrt 0.2884990253411307 0.0757151549562211 0.9396457186931516 1.0 1.0 7 Q8WUX9,O43633,Q9NZ09,Q96FZ7,Q9BRG1,Q99816 6 +Viral messenger rna synthesis 0.1914549811818242 0.0751660029043182 0.9400826335581248 1.0 1.0 36 Q8NFH4,Q96EE3,P35269,O15514,Q8NFH5,P19387 6 +Cd28 dependent vav1 pathway 0.2926415738104556 0.0751348810030549 0.9401073952219798 1.0 1.0 4 P63000 1 +Assembly of the orc complex at the origin of replication 0.2817534313341746 0.0748455398229974 0.9403376078666166 1.0 1.0 8 Q9Y619,Q9UBD5 2 +Pten regulation 0.1973416327654737 0.074448469986212 0.9406535423084992 1.0 1.0 66 P28074,P14373,P49721 3 +Vxpx cargo targeting to cilium 0.2586535788284418 0.0724304940198645 0.942259317799824 1.0 1.0 10 Q96KP1,Q9NV70,O00471,Q92538 4 +Sphingolipid de novo biosynthesis 0.2483950989796215 0.0709520527594922 0.9434359156163834 1.0 1.0 11 O15269 1 +Hiv life cycle 0.1961690462156607 0.0694087882506629 0.9446642337794616 1.0 1.0 78 Q8NFH4,Q96PU5,P23193,Q8NFH3,P62487,Q92804,P55199,Q96EE3,P35269,Q8IXH7,Q8WX92,O15514,P19387,P50750,Q8NFH5,Q9HBM6,Q15369 17 +Microrna mirna biogenesis 0.2459296026591169 0.068985168618166 0.945001425100824 1.0 1.0 11 P19387,O15514 2 +Hdr through mmej alt nhej 0.2737641519393467 0.0686160488712485 0.9452952438237878 1.0 1.0 8 P18887,P49959 2 +L1cam interactions 0.1777259527232043 0.0644493033179287 0.9486124732253208 1.0 1.0 35 P63000,P50570,O95782,Q12955,Q96CW1,Q13740,P51812,Q96P70,P63010 9 +Translocation of slc2a4 glut4 to the plasma membrane 0.1752111455294979 0.0632227698555856 0.949589113324983 1.0 1.0 33 O00186,Q9BUF5,P61981,P63000,P31751,P61026,Q9NV70,Q8IYI6,Q96KP1,P54619,O60343,O00471,Q86YS7,O00161 14 +Rho gtpases activate iqgaps 0.2633715078242691 0.0617291602144646 0.950778517751404 1.0 1.0 8 Q13576,P63000 2 +Mitotic telophase cytokinesis 0.2127358008925741 0.058383729978067 0.9534429742610182 1.0 1.0 13 Q8WVM7,P53350,Q29RF7,Q9UQE7,O60216,Q8N3U4 6 +Eukaryotic translation initiation 0.1471490058073833 0.0577806640089146 0.9539233403284736 1.0 1.0 97 Q9Y262,P60228,P08708,P62244,P83731,P62750,P06730,P05198,O15372,P61254,P23396,P46783,Q7L2H7,P55010,O15371,P62841,P46776,P23588,Q14232,P27635,P18621,Q9Y3U8,O75822,P62263 24 +Gpvi mediated activation cascade 0.2640766132314634 0.0564283411114684 0.9550005799765412 1.0 1.0 6 P61586 1 +Srp dependent cotranslational protein targeting to membrane 0.1667624178995611 0.0542610997471676 0.9567271417751 1.0 1.0 90 P61619,Q9Y5M8,P08708,P62244,P83731,P62750,P67812,P23396,P46783,P51571,P04843,P62841,P39656,P46776,P09132,P61009,P18621,Q9Y3U8,P49458,P62263 20 +Signaling by moderate kinase activity braf mutants 0.2379713914174328 0.0535705430270864 0.9572773260583788 1.0 1.0 9 P46940,P35232,P30086,P28482,Q13555,P41240,P31946,Q9Y490 8 +Post translational modification synthesis of gpi anchored proteins 0.2446035254687762 0.0523530909943869 0.958247350787127 1.0 1.0 8 O60762,Q969N2 2 +Nef mediated downregulation of mhc class i complex cell surface expression 0.2559078485436061 0.0522857855537555 0.958300979309492 1.0 1.0 5 Q9BXS5,P04439,Q10567 3 +Signaling by csf3 g csf 0.2472384665367122 0.0511222790049229 0.9592280831238664 1.0 1.0 7 P40763,P42224,P62993,P07948,Q93034,Q15369 6 +Map2k and mapk activation 0.2378940526486827 0.0498252461989 0.9602616481079762 1.0 1.0 8 Q9Y2Q5,P46940,P30086,P28482,P41240,P31946,Q9Y490 7 +Recycling of eif2 gdp 0.2490259740259842 0.0494862838884937 0.96053176767925 1.0 1.0 5 Q9UI10,Q14232,P20042,P05198 4 +Inactivation of csf3 g csf signaling 0.2471581682364451 0.0492084346997529 0.9607531894932912 1.0 1.0 6 P40763,P42224,P07948,Q93034,Q15369 5 +Selenoamino acid metabolism 0.1208796206519495 0.0489140604716934 0.9609877836393884 1.0 1.0 87 P62424,P61353,Q13155,P49591,P54136,P23396,P62269,P39023,P23526,P30050,Q02543,P32969,P62910,P62913,P56192,P05388,P08865,P18077,P61513,Q02878,P62249,P62241,P46779,P00390,P62277,P39019,P62280,P18124,Q12904,P42766,P62847,P62861,P25398,P62841,P62888,P46781,P60866,P41252,O43324,P18621,O43252,P47897,P46782,P47914,P26373,Q9P2J5,P62081,P62701,P08708,P62244,P83881,P62851,P62906,P62753,P46783,Q16881,P63220,P40429,P46776,P62917,P07814,P62263,P35268,P50914,P49207,P61927,Q15046,P62829,Q07020,P83731,P62750,P61254,P62273,P63173,P84098,P61313,P14868,P15880,P61247,P36578,P46777,P46778,P27635,P62266,Q9Y3U8 85 +Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.2180328345491359 0.0410801217571061 0.9672320217643556 1.0 1.0 5 P12235 1 +Signaling by pdgfr in disease 0.2057689384057872 0.0398795538005179 0.9681891518374126 1.0 1.0 6 O43815 1 +Cytosolic iron sulfur cluster assembly 0.2045454545454603 0.0390555071213079 0.9688461340562584 1.0 1.0 5 Q6FI81,Q96T76,P53384,P28340 4 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3b06ecbb3ca0ced1e4304e3d6318ed01a0a4ac3c --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of gene expression by srebf srebp", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pe", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha defensins", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd22 mediated bcr regulation", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate biosynthesis", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of particulate exogenous antigens phagosomes", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Dectin 2 family", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Defensins", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of base excision repair", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Elevation of cytosolic ca2 levels", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythrocytes take up carbon dioxide and release oxygen", "Erythropoietin activates phosphoinositide 3 kinase pi3k", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Erythropoietin activates stat5", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Ncam1 interactions", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O glycosylation of tsr domain containing proteins", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr regulates axonogenesis", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Phase 0 rapid depolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 24 hydroxycholesterol", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc transporters"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APBB1", "APEH", "APEX1", "APLP2", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8A", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3B", "ATG3", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATRIP", "ATRX", "AURKA", "AURKB", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BARD1", "BASP1", "BAX", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCKDHA", "BCKDHB", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BRCA1", "BRD1", "BRD2", "BRD4", "BSG", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "CAB39", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC22", "CCDC59", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA5", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2A", "CENPC", "CENPI", "CENPP", "CENPQ", "CENPU", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHST14", "CHTOP", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLNS1A", "CLSPN", "CLTB", "CLTC", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT9", "COA1", "COG2", "COG5", "COG6", "COG7", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ9", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC3", "DNAJC7", "DNAJC8", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLK", "DPM1", "DPYSL2", "DPYSL5", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHD1", "EHHADH", "EHMT1", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERLEC1", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESCO2", "ESD", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF2", "FAHD1", "FAM114A2", "FAM3C", "FAM49B", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FIP1L1", "FIS1", "FKBP14", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FOXK1", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "FYTTD1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLS", "GLUD1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPI", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILK", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INCENP", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "ISCU", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIN9", "LIPA", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMO7", "LNPEP", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPPRC", "LRRC1", "LRRC8A", "LRRC8C", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LYN", "LYPLA1", "M6PR", "MAGED2", "MAGT1", "MAIP1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAPK1", "MAPRE1", "MARC1", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MFN1", "MFN2", "MGAT1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYDGF", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1C", "MYO6", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAPA", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCOR1", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NLN", "NME1", "NMT1", "NNT", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN4", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCK2", "PCMT1", "PCNA", "PCYOX1L", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELP1", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "POFUT1", "POFUT2", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPID", "PPIE", "PPIH", "PPIL3", "PPIL4", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUS1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QTRT2", "RAB10", "RAB11B", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBBP7", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "REPS1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIPK1", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPS1", "RP2", "RPA1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP36", "RRP7A", "RRP8", "RRP9", "RSF1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SC5D", "SCAMP1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35B2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLIT2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX9", "SOAT1", "SOD2", "SORD", "SPAG9", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPOP", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX10", "STX18", "STX3", "STX5", "STX6", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SYMPK", "SYNE2", "SYS1", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL3", "TCEA1", "TCP1", "TDRKH", "TECR", "TERF2", "TERF2IP", "TEX10", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TLE3", "TLN1", "TM7SF2", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM126B", "TMEM59", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMX3", "TNPO1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRMT1", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSG101", "TSN", "TSNAX", "TST", "TTC26", "TTC37", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAP1", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBIAD1", "UBN1", "UBR4", "UBTF", "UCHL5", "UFD1", "UFL1", "UGGT1", "UHRF1", "UMPS", "UNC119B", "UPF1", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USO1", "USP10", "USP14", "USP19", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WBP11", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WFS1", "WIPI2", "WTAP", "XAB2", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YES1", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZMYM2", "ZNF512B", "ZNF638", "ZW10", "ZWILCH"], "leading_proteins": ["AARS", "ABAT", "ABCE1", "ACADM", "ACBD3", "ACOX3", "ACP6", "ACSL1", "ACSL6", "ADD1", "ADD3", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AKR1B1", "AKT2", "ALCAM", "ALDH1B1", "ALDH7A1", "ALG1", "ALG13", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC5", "ANAPC7", "ANK3", "AP1B1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "APOO", "ARFGAP1", "ARID2", "ARL1", "ARL2", "ARL3", "ARMCX3", "ARPC3", "ASH2L", "ASNA1", "ATP13A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5C1", "ATP5J2", "ATP5L", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATRIP", "BAG2", "BAG4", "BAIAP2", "BARD1", "BAX", "BCAP31", "BOLA2*", "BRCA1", "BRD2", "BSG", "BUB1B", "BUB3", "C19orf70", "C2CD5", "CALR", "CALU", "CAMK2G", "CARM1", "CARS", "CBX1", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD47", "CDC23", "CDC34", "CDCA5", "CDCA8", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2A", "CENPC", "CENPI", "CENPP", "CHCHD3", "CHD8", "CHEK1", "CHMP2A", "CHMP6", "CHMP7", "CIAPIN1", "CLSPN", "CLTC", "CNOT9", "COA1", "COG2", "COG5", "COG7", "COLEC12", "COPG1", "COPS2", "COPS4", "COX4I1", "COX6C", "CPSF2", "CPT1A", "CRKL", "CSK", "CSNK1A1", "CSNK2B", "CTBP2", "CTPS1", "CTR9", "CUL1", "CUL5", "CYB5B", "CYFIP1", "CYFIP2", "CYP51A1", "DARS", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DDOST", "DDRGK1", "DDX6", "DERL1", "DHCR24", "DHFR", "DHX36", "DNAJA1", "DNAJC3", "DNAJC7", "DNM2", "DOCK7", "DOHH", "DPM1", "DST", "DUSP9", "DYNC1LI1", "EEF1E1", "EEF2", "EHMT1", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B4", "EIF2S1", "EIF2S2", "EIF3D", "EIF3E", "EIF3H", "EIF3J", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF5", "ELL", "ELOC", "EMC3", "EMD", "EPB41", "EPB41L3", "EPB41L5", "EPRS", "ERAP1", "ERBIN", "ERCC6L", "ERO1B", "EXO1", "EXOC1", "EXOC2", "EXOC5", "EXOC8", "EXOSC2", "EXOSC3", "EXOSC7", "EXOSC8", "FANCD2", "FANCI", "FARP1", "FARSA", "FARSB", "FASN", "FAU", "FDPS", "FDXR", "FKBP14", "FKBP5", "FN3KRP", "FOXK1", "FXR1", "GABARAPL2", "GAK", "GAPVD1", "GARS", "GBF1", "GGCX", "GINS3", "GINS4", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GOSR1", "GOSR2", "GPAM", "GPS1", "GPX8", "GRB2", "GSR", "GSTO1", "GTF2F1", "GTF3C3", "GTF3C4", "GTF3C5", "HAUS3", "HAUS4", "HDAC1", "HDGF", "HINT2", "HLA-A", "HLA-C", "HLTF", "HMOX1", "HMOX2", "HNRNPF", "HSD17B12", "HSD17B7", "HSP90AA1", "HSPA2", "IARS", "ICE2", "ICMT", "IDH2", "ILK", "INCENP", "INTS14", "INTS5", "IPO5", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "ITCH", "KARS", "KDELR1", "KDELR3", "KDM1B", "KDM2A", "KEAP1", "KHDRBS3", "KHSRP", "KIF11", "KMT2A", "KNTC1", "KPNA2", "L2HGDH", "LAMTOR2", "LARS", "LBR", "LEMD2", "LEMD3", "LIN9", "LMAN1", "LMAN2", "LPCAT1", "LRRC8C", "LSM5", "LSM6", "LSS", "LYN", "M6PR", "MAN1A2", "MAN2A1", "MAPK1", "MAPRE1", "MARCKS", "MARS", "MCL1", "MCM2", "MCM3", "MCM7", "MED1", "MED14", "MED16", "MED25", "MED27", "MGAT1", "MGST1", "MIA2", "MIA3", "MID1", "MMS19", "MOGS", "MORF4L1", "MOV10", "MPG", "MPI", "MPRIP", "MRE11", "MSH2", "MTAP", "MTMR12", "MTMR2", "MTOR", "MTX1", "MYH10", "MYH9", "MYO6", "NAMPT", "NANS", "NARS", "NCAPD2", "NCAPG", "NCOR1", "ND1", "NDUFA13", "NDUFA5", "NDUFB10", "NDUFB3", "NDUFB4", "NECAP1", "NEDD4L", "NEFL", "NELFB", "NELFCD", "NHP2", "NMT1", "NNT", "NPEPPS", "NSD2", "NSL1", "NT5C3B", "NUB1", "NUBP1", "NUDT19", "NUDT9", "NUP133", "NUP155", "NUP160", "NUP35", "NUP37", "NUP43", "NUP88", "NUP93", "NUP98", "OCLN", "OGDH", "ORC2", "ORC3", "ORC6", "P3H1", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAPSS1", "PARN", "PCF11", "PDCD6IP", "PDS5A", "PEBP1", "PELP1", "PEX14", "PFDN1", "PFDN2", "PFN2", "PHB", "PICALM", "PIGT", "PIK3R4", "PIP4K2C", "PLIN3", "PLK1", "PMAIP1", "PMPCA", "PNPLA6", "POLA2", "POLD1", "POLD2", "POLE2", "POLE4", "POLR1C", "POLR2C", "POLR2D", 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0000000000000000000000000000000000000000..534f838b34e5b674e2fea687697fb5288f95f17b --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..be0cba0a35055ca64dbde0ca59404c78c1caeecd --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,221 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Overview of nanoparticle effects 0.8507946805059932 2.8334954338808855 0.0046041965743812 0.9346085435146234 0.0647876232252221 2 P09601 1 +Hostpathogen interaction of human coronaviruses apoptosis 0.7868958806357407 2.5373234887657117 0.0111703682453703 0.9986914507196022 0.0929815159579417 2 Q07812 1 +Mecp2 and associated rett syndrome 0.6322681254085161 2.5123899704466774 0.0119916493211147 0.99919920080645 0.0969116992901965 21 Q13451,P67809,P42345,Q00013,O75376,P52597,Q13547,Q05086,Q03518 9 +Robo4 and vegf signaling pathways crosstalk 0.7807330522218521 2.50820979399477 0.0121344598096015 0.999264773469508 0.0969116992901965 2 O94813 1 +Ovarian infertility 0.8731343283582068 2.449564815631217 0.0143028964907878 0.9997993695253544 0.1017861150021038 3 Q8WXH0,P11802 2 +Mrna protein and metabolite inducation pathway by cyclosporin a 0.8721589983969473 2.4454522098992366 0.0144670620307558 0.9998181782301848 0.1017861150021038 3 Q15758 1 +Congenital generalized lipodystrophy cgl 0.7392150502756978 2.3095397428417517 0.0209136489524386 0.999996239818315 0.1346138888419756 2 P31751 1 +Nocgmppkg mediated neuroprotection 0.8400002543800837 2.3087920546911755 0.0209551231361451 0.9999963327871408 0.1346138888419756 3 P07196 1 +Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway 0.8034435761938139 2.1509685875057034 0.0314786791608514 0.999999993826539 0.1898357080006449 3 P09601 1 +Hostpathogen interaction of human coronaviruses autophagy 0.7949493715594158 2.1139268653834877 0.0345215142469335 0.99999999903866 0.1932437815371504 3 P42345 1 +Histone modifications 0.7694864760219753 2.1085133780252865 0.0349866068096025 0.99999999927689 0.1932437815371504 10 Q03164,Q15047 2 +Ciliopathies 0.6516991431754525 2.0693171134827937 0.0385163387624483 0.9999999999170784 0.2088362954918069 14 Q9NQH7,Q9NVR5,Q13432 3 +Complement and coagulation cascades 0.6879662666234146 2.058285717806784 0.0395627143709154 0.9999999999564302 0.2106447224613604 2 P49257 1 +Cell cycle 0.4470224734540603 1.9994429898456003 0.0455604444413855 0.9999999999989252 0.2274974366314241 46 P42771,P61981,Q9UJX3,Q13616,Q9H1A4,P14635,Q9Y619,P25205,Q8N3U4,Q13547,Q9UJX4,P24941,Q13416,O14757,P11802,Q9UBD5 16 +Dna damage response 0.547587363328566 1.9901237117674704 0.0465773093610868 0.9999999999994276 0.2274974366314241 22 Q9BXW9,Q13794,P14635,Q07812,O14757,P24941,P49959,P41440,P11802,Q00535 10 +Urea cycle and related diseases 0.6707752189425762 1.9725657531862884 0.0485450580281778 0.9999999999998312 0.2275044304940174 2 Q9Y619 1 +Thermogenesis 0.5160239185044746 1.969563389834171 0.0488884309183421 0.9999999999998636 0.2275044304940174 27 P33121,O43772,P50416,P51812,Q9UKU0,Q12824 6 +Dna replication 0.5031510585054956 1.9531651127265444 0.0508000335350136 0.9999999999999584 0.2332114744845326 29 P40938,P49736,Q9Y619,P25205,P49005,P24941,Q13416,P41440,Q9UBD5 9 +Translation factors 0.4851285551269859 1.925836718345869 0.0541247650676726 0.9999999999999948 0.2387040071208583 33 O15372,P60228,Q05639,P55010,O15371,O75153,P19525,O75822,P23588,P05198 10 +Mirna regulation of dna damage response 0.5308593703438987 1.921876132388942 0.0546213457151951 0.9999999999999962 0.2387040071208583 23 Q9BXW9,Q13794,P38398,P14635,Q8WXE1,Q07812,P33993,O14757,P24941,P49959,P41440,P11802,Q00535,Q92878 14 +Mitochondrial long chain fatty acid betaoxidation 0.6087737384964415 1.9209690066196468 0.0547356149645406 0.9999999999999964 0.2387040071208583 15 P11310,P33121,O43772 3 +Cholesterol biosynthesis with skeletal dysplasias 0.8353226892756658 1.9162436239954213 0.055334093021248 0.9999999999999976 0.2387040071208583 6 Q14739,Q15392 2 +Neuroinflammation 0.6532598118715429 1.8845254184425553 0.0594939399035228 0.9999999999999998 0.2476121019928308 2 P42345 1 +Dna mismatch repair 0.5522311013938839 1.8780048601273336 0.060380500223391 1.0 0.2495445848393293 19 P41440,Q9UQ84 2 +Cerebral organic acidurias including diseases 0.825541596975773 1.8615867161088913 0.0626613671536875 1.0 0.2523702836334577 5 P48735,P49419 2 +Sulfation biotransformation reaction 0.7376995672091899 1.860800859775318 0.0627723040509615 1.0 0.2523702836334577 3 O43252 1 +Genes controlling nephrogenesis 0.809722155330414 1.8116735051484705 0.0700366598184678 1.0 0.2688114541783394 6 Q9Y5K6,Q13418,O94813 3 +Retinoblastoma gene in cancer 0.433386535376032 1.797099451126266 0.07231983285001 1.0 0.2688114541783394 44 P40938,P31350,P00374,P14635,Q9Y619,P25205,P33993,Q13547,Q14527,P56282,P24941,Q16204,O14757,P11802 14 +Cytosine methylation 0.7978447556285813 1.7490958565611916 0.0802744513417144 1.0 0.2878619718719205 5 P48735 1 +Circadian rhythm genes 0.4399893044271017 1.7485573990864602 0.0803675555987595 1.0 0.2878619718719205 40 Q13616,Q03164,O75376,P50416,P43490,Q13547,P11802,Q05086 8 +Development of ureteric collection system 0.7935828829121414 1.7317037028762328 0.0833263310226994 1.0 0.2913956309728722 5 Q13418,O94813 2 +Ppar signaling pathway 0.5244427126612101 1.6928836231059363 0.0904776211769613 1.0 0.3055558520890523 19 P50416,P11310,P33121,O15254 4 +Ethanol effects on histone modifications 0.6567783298105665 1.6795590636430078 0.0930431380870597 1.0 0.3106694610703521 11 Q96KQ7,P41440,Q13547,P00374 4 +Mitochondrial complex i assembly model oxphos system 0.4601137722398902 1.658725178723456 0.0971711833005883 1.0 0.3188387983895536 31 Q9NPL8,O43676,P03886,O95168,Q96CU9,O96000,Q9GZY4,Q9P0J0 8 +Fragile x syndrome 0.4540711285818871 1.6359990555703003 0.1018397850549677 1.0 0.3288924205873547 32 P42771,Q9NZ01,Q00610,P62993,P50570,P42345,P50416,O95782,P80404,Q96CW1,P28288,Q9Y4R8,Q96F07,P63010,P17252,P06730,Q7L576 17 +Nucleotidebinding oligomerization domain nod pathway 0.7658065946913154 1.6304325285021424 0.1030101144475346 1.0 0.330864008904853 6 Q9P0J0,Q96RT1,Q9Y2Z0 3 +Mthfr deficiency 0.7427691222125826 1.6147909553626234 0.1063559724865397 1.0 0.3379375254814246 7 Q96KQ7,P49419 2 +G1 to s cell cycle control 0.4720824828151664 1.5428072236976378 0.1228775562730217 1.0 0.3746880238562286 24 P42771,Q14181,P49736,P14635,Q9Y619,P25205,P33993,P56282,P24941,Q13416,P11802,Q9UBD5 12 +Overview of interferonsmediated signaling pathway 0.5844956211482253 1.532929594717337 0.1252932030693578 1.0 0.3760166133144174 2 P17252 1 +Oxidative phosphorylation 0.4342318904648076 1.52761991685775 0.1266069338005278 1.0 0.3763168137573817 34 O75964,P03886,O95168,O96000,P00846,P56134 6 +Pkcgamma calcium signaling pathway in ataxia 0.5822251054167984 1.5211890947661029 0.1282123913000268 1.0 0.3788676162915792 2 P23634 1 +Pparalpha pathway 0.694439472043262 1.490973764615204 0.1359683830184153 1.0 0.3952073671548123 8 P50416,P11310 2 +Nsp1 from sarscov2 inhibits translation initiation in the host cell 0.5740711077316943 1.4892682071316532 0.1364167561752651 1.0 0.3952073671548123 13 P60228,P55010,O15371,O75822,P05198 5 +Purinergic signaling 0.652822842310187 1.4761123336491633 0.1399137384240543 1.0 0.4014030068379421 3 P63096,P08754 2 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.7310881512984251 1.4647638543002457 0.1429853566942531 1.0 0.4082335546198242 4 P09601 1 +Atr signaling 0.6489292667099306 1.4582728651197585 0.1447653464676785 1.0 0.4113284603961444 3 O14757,Q8WXE1 2 +Fatty acid betaoxidation 0.4601408397868159 1.370115497969132 0.1706508507205781 1.0 0.4626360219076225 22 P11310,P33121,O43772 3 +Integrated cancer pathway 0.5148218822538697 1.359244619230817 0.1740690866261764 1.0 0.4681625382142672 15 P38398,Q07812,P24941,P49959,O14757,P43246,P11802,Q92878 8 +1q211 copy number variation syndrome 0.6134983176187364 1.3517977929937266 0.1764400103721182 1.0 0.4711789756646515 10 Q9NPH0 1 +Proteasome degradation 0.3981939218434137 1.343321803373632 0.1791677950341932 1.0 0.4727150306482509 39 P60900,P04439,P28074,O00231,P20618,Q15008,P04843,Q99436,P28070,P28072,P49721,Q9UL46,P25787,P10321 14 +Insulin signaling in adipocytes normal condition 0.6798182949273003 1.2541119202985485 0.2098013282444695 1.0 0.5423598242653402 4 P42345,P31751 2 +Insulin signaling in adipocytes diabetic condition 0.6798182949273003 1.2541119202985485 0.2098013282444695 1.0 0.5423598242653402 4 P42345,P31751 2 +Hedgehog signaling pathway wp4249 0.6793476319000304 1.2521776621687448 0.2105051336735921 1.0 0.5423598242653402 4 O43791,P48729 2 +Sudden infant death syndrome sids susceptibility pathways 0.4225548417611634 1.2481166062657634 0.2119883577077725 1.0 0.5423598242653402 27 P11310 1 +Apoptosis modulation and signaling 0.5298396084927179 1.2429566710305118 0.2138838006010921 1.0 0.5425121294216543 13 P42771,Q13794,Q07812,Q07820,O95831 5 +Transcriptional activation by nrf2 in response to phytochemicals 0.6742826639534321 1.2390715131344845 0.2153190155442264 1.0 0.5438185392591358 5 P09601 1 +Aryl hydrocarbon receptor pathway wp2873 0.666201155801913 1.2142394243820585 0.2246563097620852 1.0 0.5576263187766003 6 Q07812,P10620 2 +Rett syndrome causing genes 0.4880275368467918 1.1980448293137531 0.230899565196871 1.0 0.5662308839475136 15 Q8WXH0,O75376,Q9BZK7 3 +Mirna regulation of p53 pathway in prostate cancer 0.6634547310251109 1.1869123221353688 0.2352622063924236 1.0 0.5721809217198452 4 O14681,Q13794 2 +Electron transport chain oxphos system in mitochondria 0.3464756273563292 1.1540163247080204 0.2484934762022357 1.0 0.5935607031318212 54 O43676,P13073,O75964,P03886,O95168,O96000,P00846,Q16718,P56134 9 +T cell receptor and costimulatory signaling 0.5824140168721543 1.152916806332908 0.2489445331615905 1.0 0.5935607031318212 3 P17252,P48729 2 +Nanomaterial induced apoptosis 0.652589280668986 1.1492580819051086 0.250449577331123 1.0 0.5935607031318212 5 O95831 1 +Cardiac hypertrophic response 0.6502754084373745 1.1477223351041834 0.2510832077545775 1.0 0.5935607031318212 6 P50750,P42345,P31751,P63000 4 +Synaptic vesicle pathway 0.5121776677393861 1.14497571814885 0.2522192160890668 1.0 0.5938707438591175 13 P50570,O95782,Q96CW1,Q13277,O00429,P63010,P12235,O94973 8 +Joubert syndrome 0.4640809966101183 1.1314633047927185 0.2578601398437175 1.0 0.5999816639670749 16 Q13432,Q10713,P42345,P61586 4 +Phosphoinositides metabolism 0.6433542478573759 1.11888243802718 0.2631902961076484 1.0 0.6052352723720631 6 Q8TBX8,Q13614,Q9C0I1 3 +Initiation of transcription and translation elongation at the hiv1 ltr 0.5877659330892082 1.1119971432071585 0.2661393786470225 1.0 0.6065585852171675 9 Q13547,Q8WX92,P50750 3 +Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.62449690482354 1.102703448414708 0.2701559687661188 1.0 0.6115295313300051 7 Q99653,P11802,Q9UHD1 3 +Transcription cofactors ski and skil protein partners 0.6389524117005605 1.0866284335633127 0.2772010537979597 1.0 0.6197038311166523 4 Q13547 1 +Type i collagen synthesis in the context of osteogenesis imperfecta 0.5400847192991151 1.0838876198887573 0.2784146294042329 1.0 0.6197038311166523 11 Q96AY3,P13674,Q32P28 3 +Autophagy 0.619860401236186 1.08275056709923 0.2789191524146015 1.0 0.6197038311166523 7 Q99570,P54619,P42345 3 +Regulation of apoptosis by parathyroid hormonerelated protein 0.6221730844227207 1.0183561702856212 0.3085087234450285 1.0 0.6673109573740204 4 Q07812 1 +Praderwilli and angelman syndrome 0.6153636581227822 1.0028960861069245 0.3159110012375783 1.0 0.6673109573740204 6 P42771,P11802,Q05086 3 +Glycosylation and related congenital defects 0.5053221716117478 1.0025188481317835 0.3160930680529581 1.0 0.6673109573740204 12 Q13724,P34949,Q9NP73,O60762,Q9BT22 5 +Nitric oxide metabolism in cystic fibrosis 0.6176566049983812 1.0000564022721472 0.3172832132353633 1.0 0.6673109573740204 4 Q86X55,O14744,O60678 3 +Tnfrelated weak inducer of apoptosis tweak signaling pathway 0.613908207348972 0.9969014935806442 0.3188123266441371 1.0 0.6679751100048943 6 Q13547,P31751 2 +Pyrimidine metabolism 0.3593913109669941 0.9947466780290872 0.3198594858399071 1.0 0.6679751100048943 39 P04183,P62487,P31350,O75414,P62875,Q9NRF8,P17812,P49005,O15514,Q9H773,Q9NR33,O15160,O14802,P56282,P19387 15 +Nucleotide metabolism 0.5395153600891631 0.9898074915201313 0.3222682224179636 1.0 0.6706356318627341 10 P30520 1 +15q112 copy number variation syndrome 0.6045739969629396 0.94727564973988 0.3434983355261933 1.0 0.7000259182620009 4 Q96CW5 1 +Caloric restriction and aging 0.5352812272089456 0.9387721965686776 0.3478477167623497 1.0 0.7038419751641992 3 P43490 1 +Synaptic signaling pathways associated with autism spectrum disorder 0.5669814462673954 0.9202814764918672 0.357425686371484 1.0 0.713310250764637 8 Q05086,P54619,P42345,P31751 4 +Glial cell differentiation 0.4651313655530191 0.9157213366625456 0.3598130710910945 1.0 0.7135890101169021 2 P09543 1 +Amyotrophic lateral sclerosis als 0.5636011253887371 0.9055186096029262 0.3651907055308503 1.0 0.7170355713246928 8 P63000,P07196,Q07812,P20339,P07197,O96008 6 +Kennedy pathway from sphingolipids 0.5915047890359573 0.8995471351596418 0.3683613011138447 1.0 0.7208659899280868 5 Q9UG56,Q9BVG9 2 +Envelope proteins and their potential roles in edmd physiopathology 0.4363553401056613 0.8924925532285561 0.3721289824534406 1.0 0.7240738557134482 15 Q14739,P62993,P50402,Q8WXH0,P42166,P61586,O94901 7 +4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression 0.5896006320879884 0.8918919504046667 0.3724508496394048 1.0 0.7240738557134482 5 Q13131,P42345,Q96KB5 3 +Folate metabolism 0.4463893511954292 0.8872010294379586 0.3749706783027651 1.0 0.7265825274653579 14 P41440,P00374 2 +Regucalcin in proximal tubule epithelial kidney cells 0.5845026540111062 0.8768741954781721 0.3805549735187554 1.0 0.7349934292470081 6 Q07812 1 +Oxidative stress response 0.5809336345433511 0.8624738882677532 0.3884267960312892 1.0 0.7423355482367961 6 P09601,P10620,P00390 3 +Disruption of postsynaptic signaling by cnv 0.5708820746644249 0.8221552273091728 0.4109885568705032 1.0 0.7696595451726251 6 P61981,Q13555 2 +Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.571671324605494 0.8203780596025577 0.4120006191152807 1.0 0.7696595451726251 5 Q13418 1 +Gaba receptor signaling 0.5578003545577728 0.8203523055352047 0.4120152964096812 1.0 0.7696595451726251 7 O95782,Q96CW1,P80404,P63010 4 +Regulation of actin cytoskeleton 0.357751381404042 0.8190127599298695 0.4127791335738391 1.0 0.7696595451726251 30 Q14344,Q8TBX8,Q9UQB8,Q96F07,P61586 5 +Dna repair pathways full network 0.3226876846443184 0.8189249542605614 0.412829231505452 1.0 0.7696595451726251 48 P40938,Q9BXW9,Q9NVI1,P29372,P18887,P38398,P49005,Q9NR33,Q9UQ84,P56282,O14757,P49959,P41440 13 +Tp53 network 0.5697066953412904 0.8087961738401294 0.4186323974050614 1.0 0.7707531055027766 4 Q07812,Q13794 2 +Complement system 0.4983377476933838 0.7946707141411661 0.4268050721499767 1.0 0.7833596200019759 10 P08754,P17252,P48729,P07942,P26885 5 +Camkk2 pathway 0.5154199985752288 0.7815232079903487 0.4344948323727449 1.0 0.7885516744764535 9 P09601,Q13586,P42345 3 +Splicing factor nova regulated synaptic proteins 0.4167724909605681 0.780713575400292 0.4349709744150996 1.0 0.7885516744764535 15 Q9Y2J2,Q12955,Q9UBB6 3 +Physicochemical features and toxicityassociated pathways 0.4677121206368847 0.7275760272144303 0.4668731598745954 1.0 0.823880307237016 11 P61586,P07196 2 +Sars coronavirus and innate immunity 0.4262082387285058 0.7223942170568084 0.4700521413331935 1.0 0.8243347641777963 2 P42224 1 +Glutathione metabolism 0.5383689258423042 0.6946630636913536 0.4872664807747449 1.0 0.8459364125771965 6 O75874,P28161 2 +Serotonin htr1 group and fos pathway 0.5389909949533161 0.693341459502515 0.4880952905056244 1.0 0.8459364125771965 5 P63096,P08754,P61586 3 +H19 action rbe2f1 signaling and cdkbetacatenin activity 0.5375346869045217 0.6878021598617633 0.4915773758128239 1.0 0.8467759113624234 5 P11802,Q13794 2 +Head and neck squamous cell carcinoma 0.4263032662067265 0.685984027232151 0.492723180828357 1.0 0.8467759113624234 13 P42771,P42345,P31751,Q13131,Q14145,P11802 6 +Omega3 omega6 fatty acid synthesis 0.536041036169197 0.6857384966590726 0.4928780262414105 1.0 0.8467759113624234 6 O15254 1 +Amino acid metabolism 0.2997607339703599 0.6822822983840028 0.4950604640025648 1.0 0.847752567016519 53 P11310,P49419 2 +Micrornas in cardiomyocyte hypertrophy 0.4415830769726039 0.6802986524045003 0.4963153776441888 1.0 0.847752567016519 12 P61586,P42345,P31751,P50750 4 +Nucleotide excision repair 0.3593350260258554 0.6545673832343825 0.5127463298244164 1.0 0.8732941813436025 21 P41440 1 +Male infertility 0.3653569486573453 0.6275672507644832 0.5302874680008016 1.0 0.8928771897107515 18 P41440,P50750 2 +Spinal cord injury 0.3778287644548506 0.6220202950940054 0.53392852304101 1.0 0.8940084904355652 16 P61586,P11802,Q08722,O94813 4 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.3433443692787867 0.6219347611927531 0.5339847667068605 1.0 0.8940084904355652 24 P56937,Q15392,Q14739,P33121 4 +Leptin and adiponectin 0.5195525500577578 0.6182986479110291 0.5363784930139963 1.0 0.8954793485064175 4 P54619,P50416 2 +Nrf2are regulation 0.4895719849826256 0.5962715142277347 0.5509938576030418 1.0 0.9146374271825762 8 P09601 1 +Type i interferon induction and signaling during sarscov2 infection 0.4527120691976573 0.5838546445918368 0.5593181101164633 1.0 0.9233435840190776 3 P19525 1 +Estrogen receptor pathway 0.4503116775991469 0.5742203515074878 0.5658186991551193 1.0 0.928885697779654 3 Q9HCL2 1 +Ampactivated protein kinase ampk signaling 0.3677983018421979 0.5681684159413273 0.569920615461625 1.0 0.933027932791746 16 P50416,P14635,P42345,P31751 4 +Mbdnf and probdnf regulation of gaba neurotransmission 0.502788597611882 0.5620276629773738 0.5740971717310965 1.0 0.9372691394836412 6 O95782,P61586,P63010 3 +Pathways affected in adenoid cystic carcinoma 0.3461547793760407 0.558184241964943 0.5767185801678241 1.0 0.9389550437443088 20 Q9UBU8,Q96RT1,Q96T88,Q99417,O75376,P38398,O14757 7 +Malignant pleural mesothelioma 0.2839970509290275 0.555788913628378 0.5783551651985659 1.0 0.9390326995394296 62 P67870,Q96T88,Q13131,Q07820,Q15047,P62993,P31751,P38398,P51812,Q08722,Q9HCK8,P05114,P07942,P11802,Q07812,O15294,Q4VCS5,P48729,P23588,Q99728,P42771,P42345,Q13616,P56545,Q99496,P54619,P24941,O95816 28 +Nuclear receptors metapathway 0.2899135785628072 0.5459938339259878 0.5850701757310892 1.0 0.9447444640903654 49 P11310,Q13451,P28161,Q13616,P50416,Q07812,P10620,Q99615,Q14145,P09601,P11802 11 +Neural crest cell migration during development 0.4842214563371796 0.5319952734290793 0.5947292691289081 1.0 0.9551222773238714 7 Q99570,P61586,P31751 3 +Apoptosis 0.4204226851583813 0.5153564920115846 0.606303929534582 1.0 0.9650280963830898 11 P42771,Q07812,Q13794 3 +Alpha 6 beta 4 signaling pathway 0.4680454119737487 0.5137470495961882 0.6074288525457012 1.0 0.9650280963830898 8 P42345,P62993,P63000,P17252,P61586 5 +Homologous recombination 0.4750243764824161 0.4988347662414623 0.6178957931323785 1.0 0.9712138663330736 7 P49005 1 +Dna irdamage and cellular response via atr 0.3050608912224085 0.4936288018096275 0.621568356115459 1.0 0.974394956138558 34 Q9BXW9,P78527,Q9NVI1,Q92900,P49736,P38398,Q9HAW4,Q8WXE1,P46063,P33993,Q9UQ84,P24941,P49959,O14757,P43246,Q99728,Q92878 17 +Hypertrophy model 0.3684722672721344 0.459658593375689 0.6457612947850468 1.0 0.9885411246856056 2 P06730 1 +Target of rapamycin tor signaling 0.4528666180019964 0.4583854269716824 0.6466755596345197 1.0 0.9885411246856056 8 Q13131,P42345,P63000,P54619 4 +G protein signaling pathways 0.3772893832794605 0.4546336264833278 0.649372838842176 1.0 0.9885411246856056 13 P63096,Q14344,P10644,Q02952,O43823,P08754,Q92667,P17252,P61586 9 +Hostpathogen interaction of human coronaviruses interferon induction 0.4720866044995356 0.4531562024957044 0.6504362675317268 1.0 0.9885411246856056 4 P42224,P19525 2 +Glycerolipids and glycerophospholipids 0.4707153215251265 0.450960804595146 0.6520177985048745 1.0 0.9885411246856056 6 Q9UG56,Q9HCL2,Q9BVG9 3 +Cytosolic dnasensing pathway 0.4316692103002644 0.4394574501005018 0.6603301066969474 1.0 0.990495160045421 9 P62875,O15160,O14802,P19388,Q14258 5 +Metapathway biotransformation phase i and ii 0.317935650434842 0.4322406561207914 0.6655665132884812 1.0 0.9915429665332915 22 Q86UY6,P10620,P78417,Q7LGA3 4 +Tca cycle aka krebs or citric acid cycle 0.3298144854392263 0.4234839507434389 0.6719422056931177 1.0 0.9915429665332915 17 P48735 1 +Genes related to primary cilium development based on crispr 0.4257909064552219 0.4182743538484552 0.675746538265152 1.0 0.9915429665332915 9 Q96J42,Q10713 2 +Lung fibrosis 0.458217932159048 0.4103920514619203 0.6815183760909791 1.0 0.9915429665332915 6 P09601 1 +Nicotine effect on dopaminergic neurons 0.4560632865089508 0.4019952748287907 0.6876875037668961 1.0 0.993700036005466 4 P17252,Q00535 2 +Follicle stimulating hormone fsh signaling pathway 0.4463635057472287 0.3723634959329078 0.7096222289436951 1.0 1.0 4 P42345 1 +Melanoma 0.3693104591745502 0.3659408497344785 0.7144092136361733 1.0 1.0 12 P42771,P63000,P31751,Q07812,P11802 5 +Tcell activation sarscov2 0.430541505113917 0.3513651174211785 0.7253144484055816 1.0 1.0 7 Q07812,P42771,P42345 3 +Egfegfr signaling pathway 0.2775845386493456 0.3294020776995256 0.7418517975663808 1.0 1.0 34 P63010,P62993,P63000,P42345,O95782,Q96CW1,Q96J02,P51812,P41240,P17252,P20339,Q9P0J0 12 +Cannabinoid receptor signaling 0.3818542440611859 0.3266931628565265 0.7438999720111856 1.0 1.0 3 P17252 1 +Photodynamic therapyinduced ap1 survival signaling 0.4216023009692019 0.3247095322063826 0.7454009196145084 1.0 1.0 7 P42771,Q07812 2 +Estrogen signaling pathway 0.3318196561790466 0.3176833693555357 0.75072512754191 1.0 1.0 2 P17252 1 +Netrinunc5b signaling pathway 0.3932131306434249 0.3100986662103808 0.7564859265165196 1.0 1.0 9 Q8TCG1,P63000,P61586,P30154 4 +Wnt signaling 0.3270083268580382 0.3073575671596813 0.7585712224766472 1.0 1.0 14 P67870,P63000,Q13555,Q9HCK8,P17252,P48729,P61586 7 +Unfolded protein response 0.4223241213673706 0.3037411654754036 0.7613250932261375 1.0 1.0 4 Q13794 1 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.3516218475924962 0.3026474184362211 0.7621585734234122 1.0 1.0 12 P50402,P42166,Q13547,P48729,O60725,P11802,P55209 7 +Eukaryotic transcription initiation 0.335123842712375 0.2896612217491273 0.7720754255634945 1.0 1.0 13 O15160,P19387,Q13418 3 +Nonalcoholic fatty liver disease 0.2465665439098109 0.2721021029330407 0.785543512626135 1.0 1.0 52 O43676,P13073,O95182,P09669,P31751,O95168,Q96J02,O96000,P08574,Q16718,Q9P0J0 11 +Bdnftrkb signaling 0.4093055503311573 0.269685509262518 0.787402209560397 1.0 1.0 4 P42345 1 +G13 signaling pathway 0.3163982888181595 0.2694188677339351 0.7876073684233351 1.0 1.0 14 Q13576,Q14344,P61586,Q7L576 4 +Dna irdouble strand breaks and cellular response via atm 0.2719447968832369 0.2541969257375315 0.7993434255278911 1.0 1.0 26 Q9BXW9,P42771,Q07812,Q9UQ84,P49959,O14757,Q00535 7 +Pancreatic adenocarcinoma pathway 0.2861038588101171 0.2456142126847936 0.8059808860783897 1.0 1.0 18 P42771,P42345,P31751,Q07812,P61586,P11802 6 +Leukocyteintrinsic hippo pathway functions 0.397191239461977 0.2400997515056012 0.8102529268482819 1.0 1.0 4 P61586 1 +Parkinubiquitin proteasomal system pathway 0.261673482896633 0.2387941075743413 0.8112652395504332 1.0 1.0 31 Q9BUF5,O14936,Q13616,P54652,Q15008,P07437,Q99460,Q9BVA1,O00231,Q9Y385,P51665,O43242,P62333 13 +Modulators of tcr signaling and t cell activation 0.3673281263356176 0.2367500992713811 0.812850666010279 1.0 1.0 9 O96000,Q12824 2 +Tumor suppressor activity of smarcb1 0.2982107743454368 0.2116265962929721 0.832398358413956 1.0 1.0 14 Q12824 1 +Dna damage response only atm dependent 0.2700069323296362 0.2101635426904994 0.8335400328143259 1.0 1.0 21 P42771,P31751,Q13794,Q07812,Q99570,P61586 6 +Photodynamic therapyinduced unfolded protein response 0.3393616863137337 0.20017464343573 0.8413439974286607 1.0 1.0 10 Q13217,P05198 2 +Energy metabolism 0.3369772601386016 0.1944870059698345 0.8457945692120867 1.0 1.0 10 P54619,Q13555,Q13547,Q15648 4 +Brainderived neurotrophic factor bdnf signaling pathway 0.2461558304640964 0.1939770687203237 0.8461938373726423 1.0 1.0 35 P63000,P67809,P42345,P29966,Q13131,P51812,Q96P70,Q7L576,Q00535,P05198 10 +Angiopoietinlike protein 8 regulatory pathway 0.256945444635957 0.1900450976740932 0.8492737916058308 1.0 1.0 24 P42345,P31751,P54619,P51812,Q99570,P41440,O14654 7 +7q1123 copy number variation syndrome 0.2396473389112099 0.1873620074437134 0.8513768087396067 1.0 1.0 42 P00846,Q02218,Q9Y5Z9 3 +Nucleotide excision repair in xeroderma pigmentosum 0.2473204272903615 0.185283973999693 0.8530063072939529 1.0 1.0 31 P41440 1 +Hostpathogen interaction of human coronaviruses mapk signaling 0.3710628350579845 0.1835728468111701 0.8543485661901913 1.0 1.0 4 P51812 1 +Base excision repair 0.2651957423922491 0.1778698448895073 0.8588251934680984 1.0 1.0 18 P18887,P49005,Q9NR33 3 +Androgen receptor signaling pathway 0.249234006816248 0.1694117620700477 0.8654727724331188 1.0 1.0 25 O75376,Q86X55,P61586,Q05086 4 +Hijack of ubiquitination by sarscov2 0.3631486314186116 0.1684781021837805 0.8662071693502345 1.0 1.0 4 Q15369 1 +Nonsmall cell lung cancer 0.2908283310404648 0.1625377721085739 0.8708823858825314 1.0 1.0 13 P42771,P62993,P31751,Q07812,P11802 5 +Hepatitis c and hepatocellular carcinoma 0.3519432313002547 0.1586462384941174 0.8739475970451751 1.0 1.0 7 P38398,P63000,P31350 3 +Lipid metabolism pathway 0.2981334994900906 0.1548738426491806 0.8769207753474051 1.0 1.0 12 P12694,P31751,Q13131,P54619,P17252 5 +Small cell lung cancer 0.3048851418695516 0.1475290526904946 0.8827144498813522 1.0 1.0 11 P11802,Q07812,P31751 3 +Insulin signaling 0.2308418489255763 0.1448579409030925 0.8848230343885306 1.0 1.0 35 P17858,P31751,P63000,P42345,Q13131,O60343,P51812,Q99570,P41440,O00161,O14654 11 +Thiamine metabolic pathways 0.3464180925520906 0.1392263113638894 0.8892713175201004 1.0 1.0 5 Q02218,P12694 2 +Notch signaling pathway 0.278991774190951 0.1374032235487124 0.8907120831926176 1.0 1.0 13 O75376,Q96J02,Q13616 3 +Physiological and pathological hypertrophy of the heart 0.3440739358870274 0.1353374159631137 0.8923451035389087 1.0 1.0 6 P61586 1 +Cell migration and invasion through p75ntr 0.3432021749813903 0.1339910952429269 0.8934096159045672 1.0 1.0 6 P61586,P31751 2 +Pathogenic escherichia coli infection 0.2458288201478044 0.131973316137088 0.8950053977497676 1.0 1.0 19 Q16625 1 +Selenium micronutrient network 0.2927898014610296 0.1255315042426037 0.900102785517146 1.0 1.0 11 Q16881,Q8NFF5,Q8WTV0,P00390 4 +Ciliary landscape 0.2122476318963402 0.1110512971686929 0.9115756689990916 1.0 1.0 100 Q9Y312,P09669,P07196,Q15555,P25205,Q13868,Q13547,Q96P70,Q13576,Q9NQH7,Q16718,P07197 12 +Neural crest cell migration in cancer 0.3133536363355992 0.1086051516908034 0.9135156744696258 1.0 1.0 8 Q99570,P61586,P31751 3 +Alzheimers disease and mirna effects 0.2100309517467637 0.1011512707820962 0.9194303785192935 1.0 1.0 72 P67870,P60900,Q15008,P28072,Q99570,O00213,Q00535,P05198,P31751,Q99436,Q13564,P49721,Q96IX5,O14654,P28074,Q9NQC3,P25787,P12235,P48729,P42345,P20618,P19525,P28070 23 +Cohesin complex cornelia de lange syndrome 0.2249874304001579 0.091989346638322 0.9267065038532164 1.0 1.0 18 Q8N3U4,P30154 2 +Oxidation by cytochrome p450 0.3104495180196464 0.0917133596239864 0.9269257826848474 1.0 1.0 6 Q9UHQ9 1 +Measles virus infection 0.2159467209365242 0.0898312048570703 0.9284213505393047 1.0 1.0 23 O15372,P54652,Q07812,P24941,P11802,P05198 6 +Sterol regulatory elementbinding proteins srebp signaling 0.2017568746488102 0.0849691857651059 0.932285888287673 1.0 1.0 32 Q8WU17,P42345,Q8WTV0,P48449,Q13131,P54619,P14324,O95487,P17252,Q9HCL2,O94979 11 +Myometrial relaxation and contraction pathways 0.2231660364300037 0.0821181503212287 0.9345527599999924 1.0 1.0 16 P61981,Q99439,Q13555,P17252,P78417 5 +Thyroid stimulating hormone tsh signaling pathway 0.2208479518118411 0.079466609545544 0.9366614893194564 1.0 1.0 16 Q14344,P11802,P42345 3 +Aryl hydrocarbon receptor pathway wp2586 0.2974991880480752 0.0792159459473191 0.9368608614177976 1.0 1.0 6 P28482,P07900,P24941,O00170,Q16543 5 +Complement system in neuronal development and plasticity 0.2866155909108301 0.079063219900498 0.936982338167306 1.0 1.0 8 Q07812 1 +Il6 signaling pathway 0.2888121723583478 0.0759777819743182 0.9394367745111412 1.0 1.0 7 Q13547,P63000 2 +Pi3kakt signaling pathway 0.1928334257373921 0.0757019135561227 0.9396562535667484 1.0 1.0 34 P62993,P31751,P63000,P30154,P42345,P38398,Q13131,Q07820,P24941,P17252,P23588,P06730,P11802 13 +Erbb signaling pathway 0.2331291967285721 0.0730031120862081 0.9418036410342994 1.0 1.0 13 P62993,P42345,P31751,Q13555,P17252 5 +Tnfalpha signaling pathway 0.2188759466728283 0.072484941870836 0.9422159885913816 1.0 1.0 15 Q07812,P63000,Q13616 3 +Hippo signaling regulation pathways 0.2126972219273076 0.0711873947316237 0.9432486135111724 1.0 1.0 16 P42345,P63000,P10644,P08754,Q13131,P54619,P17252,P61586 8 +Nanoparticlemediated activation of receptor signaling 0.2852969814995169 0.0693250328920632 0.9447309003019272 1.0 1.0 4 P62993,Q9Y490,P28482 3 +Il2 signaling pathway 0.2845079571289461 0.0688437042334136 0.9451140296407884 1.0 1.0 6 P42224,P62993,P28482,P62753,P46109 5 +Pdgf pathway 0.2640732572786821 0.0686938918970694 0.9452332802802864 1.0 1.0 9 P61586,P63000 2 +Epo receptor signaling 0.2844155844155892 0.0686648054242319 0.9452564332588522 1.0 1.0 5 Q15118,P42224,P28482,P62993 4 +Bladder cancer 0.2831899555311806 0.06778254183147 0.945958741396064 1.0 1.0 5 P11802 1 +Cholesterol biosynthesis pathway 0.2301136202174565 0.0637202203107183 0.9491930039844068 1.0 1.0 12 P48449,O75845 2 +Primary focal segmental glomerulosclerosis fsgs 0.2015389172639083 0.062252811909741 0.9503615061867348 1.0 1.0 16 Q9Y5K6,Q13418 2 +Leptin signaling pathway 0.1962939241218492 0.0613421885197372 0.9510866924642488 1.0 1.0 20 P62993,P63000,P42345,Q07812,Q13131,P61586 6 +Alzheimers disease 0.1903680385801396 0.0609840733618208 0.9513718930614674 1.0 1.0 71 P67870,P60900,Q15008,P28072,Q99570,O00213,Q00535,P05198,P31751,Q99436,Q13564,P49721,O14654,P28074,Q9NQC3,P25787,P12235,P48729,P42345,P20618,P19525,P28070 22 +Gastric cancer network 2 0.2160838533139672 0.0603177689373492 0.9519025501464908 1.0 1.0 13 P40938,Q14739 2 +Agerage pathway 0.2216114842495937 0.058505992497765 0.9533455893501372 1.0 1.0 12 P39656,P61586,P63000 3 +Kisspeptinkisspeptin receptor system in the ovary 0.2664252316894326 0.0573743437210341 0.9542470000724376 1.0 1.0 5 P31751 1 +Ranklrank signaling pathway 0.2448719897513525 0.0567992660359285 0.954705098614438 1.0 1.0 9 P42345,P31751 2 +Wnt signaling pathway and pluripotency 0.1911635642506928 0.0540693769939641 0.9568798901629828 1.0 1.0 15 P61586 1 +Pdgfrbeta pathway 0.2516755053020253 0.0508976581348081 0.9594070716306844 1.0 1.0 6 P19525,P62993 2 +Translation inhibitors in chronically activated pdgfra cells 0.1732972649384592 0.0492296439227825 0.96073628746679 1.0 1.0 16 P17252,P23588,P42345,P31751 4 +Hepatitis b infection 0.1719412724306721 0.048309925084686 0.9614692447172316 1.0 1.0 20 P05771,P42224,Q16531,P28482,Q15904,P63104,P40763,P12004,P62993,P31751,Q15750,O00571,P49327,Q07812,P27348,Q7Z434,Q9Y277,P31946,P17252 19 +Interactome of polycomb repressive complex 2 prc2 0.2416368950958188 0.0473574412621859 0.9622283478907314 1.0 1.0 6 O75530,Q15022,P55199,Q9NYF8,Q9Y2W1 5 +Glycogen synthesis and degradation 0.1829427083333357 0.0473088551958745 0.962267070560946 1.0 1.0 13 P63151,P30153,Q15257,P30154,P46976,P13807,P19367,Q14738,P06737,P35573,P52789,P11216 12 +Tolllike receptor signaling pathway 0.2342975446169255 0.0467734881556143 0.9626937592866384 1.0 1.0 7 P31751 1 +Kit receptor signaling pathway 0.1715494791666694 0.0452241877907979 0.9639286149018648 1.0 1.0 13 P40763,P05771,P42224,P62993,P46108,P07948,P28482,P62753,P51812,P17252,P46109,Q15418 12 +S1p receptor signal transduction 0.2275197444787512 0.0449786659883994 0.964124313816227 1.0 1.0 7 P63096,P08754,P31751 3 +Nongenomic actions of 125 dihydroxyvitamin d3 0.2256442236355177 0.044534046805763 0.9644787134622224 1.0 1.0 7 Q13555,Q15648 2 +Embryonic stem cell pluripotency pathways 0.2141077007789906 0.0436000776460042 0.9652231898054576 1.0 1.0 8 P31751 1 +Oncostatin m signaling pathway 0.1619897063103466 0.041843961169106 0.9666230897381828 1.0 1.0 11 P24941,P62993,P42345 3 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6dffa6634f48f7d3a8cfc3f3c9da5043a90b8972 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Ganglio sphingolipid metabolism", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes associated with the development of rheumatoid arthritis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpr143 in melanocytes and retinal pigment epithelium cells", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactions of natural killer cells in pancreatic cancer", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoblast signaling", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAR2", "AARS", "AASS", "ABAT", "ABCB1", "ABCC1", "ABCD3", "ABCF1", "ABCF2", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANXA1", "ANXA2", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APBB1", "APEX1", "APLP2", "APMAP", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARL8B", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATIC", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AURKA", "AURKB", "BAG2", "BAG3", "BAG4", "BAIAP2", "BAK1", "BANF1", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BCAS3", "BCAT2", "BCKDHA", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BLM", "BLVRA", "BMI1", "BPTF", "BRCA1", "BRD1", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "C1QBP", "CAAP1", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CANT1", "CAP1", "CAPN1", "CAPN2", "CAPZB", "CARM1", "CASK", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR2", "CCDC124", "CCDC6", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC73", "CDCA5", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2A", "CEBPZ", "CECR2", "CELF1", "CELF2", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHMP6", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CIP2A", "CKB", "CLASP1", "CLCN7", "CLIC1", "CLPTM1L", "CLSPN", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT9", "CNP", "COA1", "COA3", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COQ8A", "COQ9", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPT1A", "CPT2", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DARS", "DCAF1", "DCAF7", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DECR1", "DEK", "DERL1", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX36", "DHX38", "DHX8", "DHX9", "DIAPH1", "DLAT", "DLD", "DLST", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DOLK", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC1", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHD1", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMD", "ENAH", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPRS", "EPS15", "ERBIN", "ERCC3", "ESCO2", "ESD", "ESS2", "ETF1", "ETFA", "ETFDH", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOSC2", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAM120A", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIS1", "FKBP10", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FOXRED1", "FSCN1", "FTL", "FTO", "FUCA1", "FUS", "FXR1", "G3BP1", "G6PD", "GABARAPL2", "GAPDH", "GART", "GBA", "GCDH", "GCLC", "GDAP1", "GGCT", "GGCX", "GGH", "GID8", "GIGYF2", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GM2A", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPI", "GPS1", "GPT2", "GRB2", "GRSF1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F2", "GTF2I", "GTPBP4", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOXD11", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP3", "ILF2", "ILK", "IMPAD1", "IMPDH2", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIDINS220", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF4A", "KIF5B", "KLC1", "KMT2A", "KMT2B", "KPNA1", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3BP", "LIG1", "LIG3", "LIN9", "LIPA", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPCAT3", "LPGAT1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM4", "LSM7", "LSS", "LTA4H", "LUC7L", "LYN", "MACF1", "MAEA", "MAGT1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MEPCE", "MFN2", "MGST1", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MOCS1", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPI", "MPP1", "MPST", "MRE11", "MRI1", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTR", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1C", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAM1", "NCAPG", "NCAPG2", "NCBP1", "NCBP2", "NCDN", "NCKAP1", "NCL", "NCOR1", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NFATC2IP", "NIPBL", "NKRF", "NME1", "NME6", "NONO", "NOP2", "NPC1", "NPC2", "NR2F2", "NSD1", "NSDHL", "NSF", "NT5C3A", "NTHL1", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCLN", "OGDH", "OGT", "OPA1", "ORC2", "ORC3", "ORC6", "OXCT1", "P3H1", "P4HA1", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELO", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGRMC2", "PGS1", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PIAS1", "PIGT", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PKN2", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMAIP1", "PMPCA", "PMVK", "PNP", "PNPLA8", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB21", "RAB2A", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RBBP7", "RBM14", "RBM17", "RBM39", "RBM4", "RBM5", "RBMX", "RBPJ", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RIF1", "RIPK1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPS1", "RP2", "RPA1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP38", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RTCB", "RTF1", "RTN3", "RTN4", "RUVBL1", "S100A10", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARS", "SC5D", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SDHC", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEL1L", "SEPT11", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SFPQ", "SFSWAP", "SGPL1", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIN3A", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC3A2", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMYD3", "SNAP23", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SPEN", "SPOP", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRPK2", "SRRM1", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSR4", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STIP1", "STMN1", "STOM", "STRAP", "STRN", "STUB1", "STX3", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SUZ12", "SYNE2", "TAB1", "TACO1", "TALDO1", "TAP1", "TARDBP", "TBC1D4", "TBCA", "TBL1XR1", "TBL2", "TCF20", "TCP1", "TECR", "TELO2", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMELESS", "TIMMDC1", "TJP1", "TK1", "TKT", "TLE3", "TLN1", "TM7SF2", "TMED10", "TMEM126B", "TMEM165", "TMEM43", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNPO1", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP3A", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRIP4", "TRRAP", "TSG101", "TTC19", "TTC26", "TTF1", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TXNDC15", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBAP2L", "UBE2J1", "UBE2L3", "UBE2N", "UBE3A", "UBIAD1", "UBR5", "UBTF", "UCHL5", "UFD1", "UGGT1", "UHRF1", "UMPS", "UNC119", "UPF1", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP10", "USP5", "USP7", "USP9X", "UTRN", "VANGL1", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS16", "VPS33A", "VPS4A", "WAPL", "WARS", "WDHD1", "WDR1", "WDR26", "WDR5", "WDR74", "WFS1", "WIPI2", "XAB2", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YES1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZEB2", "ZFR", "ZMPSTE24", "ZNF281", "ZNF318", "ZYX"], "leading_proteins": ["AAR2", "ABAT", "ABCD3", "ACADM", "ACOX3", "ACP6", "ACSL1", "ACSL6", "ADSS", "AGL", "AIFM1", "AIP", "AKAP1", "AKAP12", "AKAP8", "AKT2", "ALDH7A1", "ALG1", "ALG13", "AMOT", "ANAPC1", "ANAPC5", "ANAPC7", "ANK3", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "APBB1", "ATP2B4", "ATP5J2", "ATP5L", "ATP6", "ATP6AP1", "ATRIP", "BAG2", "BAIAP2", "BARD1", "BAX", "BCKDHA", "BCLAF1", "BRCA1", "CAMK2G", "CARM1", "CASK", "CCDC6", "CCNB1", "CD2AP", "CD47", "CDC37", "CDK2", "CDK4", "CDK5", "CDK9", "CDKN2A", "CHD8", "CHEK1", "CHORDC1", "CHP1", "CIP2A", "CLSPN", "CLTC", "CLUH", "CNN2", "CNP", "COA1", "COX4I1", "COX6C", "CPT1A", "CRK", "CRKL", "CSK", "CSNK1A1", "CSNK2B", "CTBP2", "CTPS1", "CTPS2", "CUL1", "CYB5R1", "CYC1", "CYFIP1", "CYFIP2", "DCTPP1", "DDB1", "DDOST", "DDX3X", "DHCR24", "DHFR", "DNAAF2", "DNAJC3", "DNAJC7", "DNM1L", "DNM2", "DPM1", "EED", "EEF1A2", "EHMT2", "EI24", "EIF2AK2", "EIF2S1", "EIF3D", "EIF3E", "EIF3H", "EIF3J", "EIF4B", "EIF4E", "EIF5", "ELL", "ELOC", "EMD", "EPB41L3", "ERBIN", "EXO1", "EXOSC2", "FANCD2", "FANCI", "FASN", "FDPS", "FKBP10", "FKBP2", "FKBP5", "FLAD1", "FOXRED1", "GNA13", "GNAI1", "GNAI3", "GPAM", "GRB2", "GSR", "GSTM2", "GSTO1", "GYG1", "GYS1", "HDAC1", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMGN1", "HMOX1", "HNRNPF", "HS2ST1", "HSD17B7", "HSP90AA1", "HSPA2", "ICMT", "IDH1", "IDH2", "ILK", "IPO9", "IQGAP2", "IRS4", "ITCH", "KEAP1", "KMT2A", "LAMB1", "LBR", "LMAN1", "LSS", "LYN", "MAPK1", "MAPRE2", "MARCKS", "MAVS", "MCL1", "MCM2", "MCM3", "MCM7", "MED1", "MGST1", "MOGS", "MORF4L1", "MPG", "MPI", "MPP1", "MRE11", "MSH2", "MTMR12", "MTMR2", "MTOR", "MYCBP", "NAA40", "NAE1", "NAMPT", "NAP1L1", "NCDN", "NCOR1", "ND1", "NDUFA13", "NDUFA5", "NDUFA7", "NDUFB10", "NDUFB3", "NDUFB4", "NEFL", "NEFM", "NELFB", "NME6", "OCLN", "OGDH", "OGT", "ORC2", "ORC3", "P3H1", "P4HA1", "PAPSS1", "PBK", "PCNA", "PDK1", "PFKL", "PIK3R4", "PIP4K2C", "PISD", "PMAIP1", "PMPCA", "POLA2", "POLD2", "POLE2", "POLE4", "POLR1C", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PRKAA1", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCB", "PRKDC", "PRMT3", "PRMT5", "PSMA2", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC6", "PSMD1", "PSMD11", "PSMD3", "PSMD6", "PSMD7", "PSME2", "PTDSS2", "PTPA", "PYGB", "PYGL", "RAB5A", "RAC1", "RAD50", "RECQL", "RFC3", "RHOA", "RNF139", "RNF2", "RPN1", "RPS6", "RPS6KA1", "RPS6KA3", "RRM2", "RTN4", "SC5D", "SCARB1", "SEC24B", "SEC31A", "SETDB1", "SLC19A1", "SLC1A5", "SLC25A15", "SLC25A20", "SLC25A4", "SLIT2", "SMARCB1", "SNAP23", "SPOP", "STAG2", "STAT1", "STAT3", "STIM1", "STX3", "SUGT1", "SUN1", "SUZ12", "SYNE2", "TAB1", "TAP1", "TBC1D4", "TBL1XR1", "TECR", "TELO2", "THRAP3", "TIMMDC1", "TK1", "TLN1", "TMPO", "TOMM40", "TRIM25", "TUBB", "TUBB2B", "TUBB6", "TUBGCP3", "TXNDC15", "TXNRD1", "UBE2J1", "UBE3A", "UBIAD1", "UHRF1", "UNC119", "UPF1", "USMG5", "VDAC3", "XPNPEP3", "XRCC1", "YBX1", "YWHAB", "YWHAG", "YWHAQ", "YWHAZ"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json b/opencell_localization/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/opencell_localization/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/opencell_localization/basic/idx2term.json b/opencell_localization/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..b250b4c1dd6781e0ec0e7d07b075847434b6fb79 --- /dev/null +++ b/opencell_localization/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "vesicles", "1": "golgi", "2": "er", "3": "cytoplasmic", "4": "membrane", "5": "nucleoplasm", "6": "centrosome"} \ No newline at 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b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..c310baa092ed72cc4b5b3813864e5548e8a1817e --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c58426f6c475f8fd9a6285cc2492f35849aae86bb04bba020a084f470daadd28 +size 67950 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..186b5ce9b6c379dbf4e0ab775b537d429e09d493 --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 88.88235294117646 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7906f652deb3060dbcc5cb4387000e0dd069ba9d --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..91cdabeced1a941ec90dfd519595b096be677753 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,10 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +vesicles 0.3144262791242976 1.3771327995468587 0.1684711936236853 0.9565575728100782 1.0 159 Q9Y5K8,Q15392,Q8IXU6,P48449,Q9Y371,O43752,O43808,O96005,Q10713,Q969V3,Q13614,Q15758,O14976,P41440,Q9UI14,Q9NP72,Q92538,P30825,O15126,P50570,P31751,Q9UM00,O14653,O75396,O00400,P61586,Q96A49,Q15907,O15145,O60476,O75845,O15269,Q8IZA0,Q93050,Q13277,Q14145,P42345,Q9C0E8,O95249,P17812,P62820,Q9Y3E0,P63010,Q7L5N7,O94979 45 +golgi 0.3229565675580461 0.923664347655518 0.3556610999229335 0.9994312204494078 1.0 58 O15126,O94979,Q9UM00,O14653,P40616,Q8IXU6,Q9Y371,P62820,Q9Y487,Q9Y3E0,O14976,Q9Y5P4,Q9UI14,Q96A49,Q8IZA0,Q92538 16 +er 0.3034626528066448 0.803791958764746 0.4215171345762458 0.999909021557938 1.0 98 Q15392,O96005,Q9Y487,Q969V3,Q9NP72,Q9P0I2,Q9UM00,Q969Q5,O75396,O75845,O15269,Q9BRK0,Q13586,Q9NQC3,Q14739,Q9C0E8,Q9Y3E0,Q7L5N7,Q9NPA0 19 +focal_adhesions 0.5394238440032292 0.6922166961899264 0.4888012551082306 0.9999888820109842 1.0 4 Q13418 1 +cytoplasmic 0.2274709973366746 0.4252929842300756 0.6706231073005873 0.999999993679038 1.0 344 Q9Y5K8,Q9Y3C8,P60228,P52292,O60749,Q9Y371,P42166,Q9UQB8,O00410,Q16637,Q99615,Q13614,O14976,Q9UL46,Q9NR45,Q8NC96,Q9UI14,Q9BRG1,Q9UN86,Q92538,Q13418,Q96KB5,Q00535,O43592,P63000,P31751,P50570,Q969Q5,P78362,P51812,Q99436,P49721,Q9UI26,P61586,P98179,P11802,Q96A49,Q9H2J4,Q15907,O15145,P46939,Q9Y4F1,P28074,P40616,P14635,P55010,O60566,Q13277,Q96N67,Q96P70,Q14145,Q92973,O14757,O95373,O95456,Q9Y5P4,P42771,P61981,P51114,P42345,O00231,P09132,P52732,P20618,P17812,Q15427,O15514,P62820,Q13555,P24941,P14324,P28070,P46379,P19387,P62263,O94979 76 +membrane 0.2599682223807498 0.3495314741586357 0.7266903460659799 0.999999999735068 1.0 79 Q8TBX8,Q9UQB8,Q15758,Q8NC96,P41440,P30825,O15126,P50570,P31751,O15145,P46939,P04439,Q9Y4F1,Q13277,Q96N67,Q9NQC3,Q13492,P61981,P63010 19 +cell_contact 0.2939113527139346 0.3472321564264309 0.728416914630285 0.9999999997621264 1.0 25 Q9UQB8 1 +nucleoplasm 0.1895607045618101 0.1245718387757667 0.90086252409758 1.0 1.0 336 Q9Y5K8,Q9Y3C8,Q8TBX8,P52292,Q9BQ61,P42166,O00410,Q13547,Q16637,Q99615,Q13614,Q9UN86,Q9UL46,Q9NR45,Q8NC96,Q9BRG1,Q96KB5,Q00535,O43592,P17480,P62487,P31751,P63000,P25440,Q7Z2T5,P78362,P51812,Q99436,P50750,P49721,Q9UI26,P61586,P98179,P11802,O15145,Q15059,Q9H2J4,P46939,P83916,P28074,Q96SY0,Q6P2C8,O14802,Q96P70,Q92973,O14757,Q8N3U4,O60244,O95456,Q9Y5P4,O95373,P42771,O95429,Q13451,P61981,Q71SY5,O00231,P35269,P20618,Q15427,O15514,Q8WUB8,Q13555,P78332,P24941,P14324,P28070,P46379,P19387,Q12824 70 +centrosome 0.1709230617007019 0.0575126075627597 0.954136863349863 1.0 1.0 26 Q8WWK9,P61981,Q9Y6G9,Q15691,Q10713,Q13561,P17252,P48729 8 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d8b9ca2ad06c4443841c8a05934e2a40ba717ccb --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AATF", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AHCY", "AHSA1", "AKAP12", "AKAP8L", "AKR1A1", "AKT2", "ALCAM", "ALDH9A1", "ALG2", "ANAPC16", "ANAPC2", "ANXA11", "AP2B1", "AP2S1", "APLP2", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8A", "ARL8B", "ARPC2", "ARPC3", "ATG3", "ATL2", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATXN10", "ATXN2L", "AURKB", "BAG4", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BLM", "BLVRA", "BMS1", "BNIP1", "BOP1", "BRD2", "BRD3", "BRD4", "BTF3", "BUB1B", "BUD23", "BYSL", "C19orf53", "C8orf33", "CAD", "CAMK2G", "CANX", "CAPRIN1", "CAPZB", "CBX1", "CCAR1", "CCDC22", "CCDC47", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKN2A", "CEPT1", "CETN2", "CHEK1", "CHMP2A", "CHMP6", "CHMP7", "CKAP2", "CKAP4", "CKAP5", "CKB", "CLASP1", "CLCN7", "CLNS1A", "CLPTM1", "CLTB", "CLTC", "CNN2", "COIL", "COL4A3BP", "COMMD1", "COPA", "COPB2", "COPG1", "COPG2", "COPZ1", "CORO1C", "CPSF6", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTCF", "CTNNB1", "CTNNBL1", "CTPS1", "CTTN", "CYB5R3", "CYP51A1", "DAD1", "DCTN2", "DDB1", "DDOST", "DDX21", "DDX39B", "DDX47", "DDX5", "DDX56", "DDX6", "DHCR24", "DHX37", "DHX9", "DIAPH1", "DKC1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB6", "DNAJC11", "DNAJC13", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DOCK7", "DRG1", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EBNA1BP2", "EDC3", "EDC4", "EDF1", "EEF1G", "EFTUD2", "EIF2AK2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3K", "EIF3M", "EIF4A1", "EIF4A3", "EIF5", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMG1", "ENO1", "EPS15", "ESD", "ESYT1", "EZR", "FAM120A", "FAM207A", "FARP1", "FASN", "FAU", "FBL", "FDPS", "FKBP5", "FKBP8", "FXR1", "G3BP1", "G3BP2", "G6PD", "GAK", "GAPDH", "GAR1", "GBF1", "GDI2", "GNL2", "GNL3", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GPAT4", "GPR107", "GRB2", "GSPT1", "GTF2F1", "GTPBP4", "GYG1", "GYS1", "H1F0", "HDAC1", "HDAC2", "HEATR3", "HLA-A", "HMGA1", "HMGB2", "HMGCS1", "HMGN2", "HNRNPA0", "HNRNPC", "HNRNPD", "HNRNPH1", "HNRNPL", "HNRNPU", "HSP90AA1", "HSP90AB1", "HSPA12A", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPH1", "IDI1", "IGF2BP1", "IGF2BP3", "ILF3", "ILK", "INTS14", "INTS5", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "KDSR", "KEAP1", "KIAA0319L", "KIAA0368", "KIF11", "KIF20A", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "LAMP1", "LAMP2", "LAMTOR2", "LARP7", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LIG1", "LMAN1", "LMNA", "LMNB1", "LNPK", "LPCAT1", "LPCAT2", "LSS", "MAN1A2", "MAP4", "MAPK1", "MAPRE1", "MBOAT7", "MCM10", "MDH1", "MECP2", "MED14", "MED17", "MED20", "MED24", "MED25", "MED27", "MED4", "MFN1", "MFN2", "MIF", "MKI67", "MPHOSPH10", "MRTO4", "MSH6", "MSN", "MTMR2", "MTOR", "MYBBP1A", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO6", "NAF1", "NANS", "NAPA", "NCAPH", "NCKAP1", "NCL", "NCLN", "NECAP1", "NECAP2", "NEK9", "NEPRO", "NHP2", "NIFK", "NOL10", "NOL11", "NOM1", "NONO", "NOP10", "NOP2", "NOP53", "NOP58", "NPM1", "NSA2", "NSDHL", "NUCKS1", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP214", "NUP35", "NUP98", "NVL", "NXF1", "OSBP", "OSBPL8", "OSTC", "PABPC4", "PAK4", "PARP1", "PBK", "PCNA", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PES1", "PEX3", "PFN1", "PGK1", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHGDH", "PI4K2A", "PI4KA", "PICALM", "PIK3C2A", "PIK3R2", "PIP4K2C", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PMPCA", "PMVK", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "PPM1G", "PRKAA1", "PRKCA", "PRKDC", "PRPF19", "PRPF4B", "PRPF8", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTDSS1", "PTDSS2", "PTGES3", "PTK7", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB7A", "RAB9A", "RABAC1", "RABL3", "RAC1", "RACK1", "RAD21", "RAN", "RANBP1", "RANBP2", "RANBP9", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM5", "RBM6", "RBM8A", "RBMX", "REEP2", "REEP3", "REEP4", "REEP5", "RER1", "RHOA", "RHOG", "RNASEH2A", "RNF40", "RPL10A", "RPL11", "RPL13", "RPL19", 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b/panther_protein_class/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f5068fdc4a80b0b84a58a0dd23599fe292a75645944ccef85d77353c4c641d1c +size 150038 diff --git a/panther_protein_class/consensus.joblib b/panther_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..32e8d4df0506686bf29a230b8821d4bfcbf39d42 --- /dev/null +++ b/panther_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a871cabd1b2ce8084c617f8418f3c0130dd7791e77ef7609d1e42f5113865d17 +size 84606 diff --git a/panther_protein_class/df_merge.tsv b/panther_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d82ee2e51a15af3466033cc16a474926b318520b --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +dehydrogenase 10 70 2.7263752699395893 0.0064034149270932 17.5 66.16747572815534 -0.3132541028475373 0.5221973758281631 9.632192181097317 4.446402542482994 1.1586451749415434 0.3556564936574932 0.0001649102160403 0.0001400296133967 0.0005336694844017 0.0010447422510194 0.0051161374243303 +transporter 15 55 2.6263822333649034 0.008629784898269 16.281553398058254 57.34708737864078 1.7781248355514696 0.2510912048406951 6.627271511266295 3.5084386843827997 1.4364723564792363 0.3433005081320681 0.1192825751361889 0.0185012393708632 0.0055454664314879 0.002230498686755 0.0016785331864895 +histone modifying enzyme 3 15 2.5340536656018693 0.011275146260449 3.6893203883495143 12.859223300970871 0.0363233460240363 0.5130278596738178 2.7307281514565176 3.475236581824501 1.0011374616004485 0.3161877703975937 0.0567667721825774 0.0021781449325651 0.0154029461510805 0.0424139427802885 0.271059420237967 +ubiquitin-protein ligase 11 52 2.433030418149237 0.0149730429629348 19.58495145631068 59.20631067961165 -0.4503192177737564 0.5340766328058972 8.123146046740304 8.77461359094909 1.127183081820805 0.3533429799231634 1.0 1.0 0.3553367787953364 0.2840414509821652 0.3797650254129333 +ATP synthase 6 20 2.284261638223116 0.0223561589922296 6.381067961165049 20.483009708737864 0.8573640874951715 0.3249378356888472 2.8850015270213047 1.3977105655851854 1.2517106680730556 0.3017789026221172 1.0 0.1389130578490434 0.2613412907301976 0.000843077267801 0.0006076085796874 +membrane traffic protein 17 59 2.126081471554305 0.0334964764091543 17.393203883495147 64.0364077669903 0.6866153002436179 0.5279969401351168 6.983388919650095 8.417857504136053 1.0746394007588131 0.378481933491251 1.0 0.1638005007397412 0.0156660237374822 0.0767167525516637 0.0070384061941362 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..032a409a9eb8caf12974f2ece232b87fdc60a7c6 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 157, + "title": "Average number of proteins per term", + "value": 13.235668789808917 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..497e6bde446457a472caadd980950577abbe1912 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d0042bc394bfcaf9392fe1fb0e749961db41d197 --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,53 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +viral or transposable element protein 0.8965293545248126 3.0392317531213413 0.0023718231996228 0.3112097955584034 0.0232735151462988 2 Q9NUD5 1 +dehydrogenase 0.4678043832744303 2.7263752699395893 0.0064034149270932 0.6352593562212876 0.0478731496930307 70 P30837,P11310,P48735,P49419,O75874,P03886,Q96CU9,Q13423,Q02218,Q9P0J0 10 +transporter 0.4831699956337994 2.6263822333649034 0.008629784898269 0.7435332435941997 0.0589076621316626 55 Q8NFH4,P61619,Q96EE3,O43772,Q15070,Q9Y619,P62072,Q92973,Q567V2,Q6N075,O60830,Q96P70,Q9UI26,P41440,Q9UJZ1 15 +histone modifying enzyme 0.7156771361019574 2.5340536656018693 0.011275146260449 0.8314045529015915 0.0680845370342498 15 Q03164,Q15047,Q9H7B4 3 +ubiquitin-protein ligase 0.4678408675536643 2.433030418149237 0.0149730429629348 0.906383112481958 0.0870654720437325 52 Q96PU5,Q96T88,Q9UJX3,O75155,Q9H1A4,Q13616,O43791,Q96J02,P14373,Q16763,Q05086 11 +ATP synthase 0.6050440052310052 2.284261638223116 0.0223561589922296 0.9712680583468786 0.1169972320593351 20 Q9Y5K8,O75964,Q9Y487,P00846,P56134,Q96IX5 6 +membrane traffic protein 0.4313316190376123 2.1260814715543055 0.0334964764091543 0.9952473006350976 0.150255622749635 59 Q12907,Q8N2H4,P63010,Q5JRA6,P20645,O95782,Q13432,Q96RL7,Q9UHQ4,Q96D71,O60313,O14976,Q96PC5,Q9BRG1,Q9UI14,A6NIH7,Q9BRK0 17 +metalloprotease 0.5003833763842034 1.7817293435999169 0.074793379305196 0.9999949941145728 0.2498417138492718 25 Q9NZ08,P55786,O43847,Q10713,P52888,Q9NQH7,Q7Z2K6,Q9BYT8 8 +mitochondrial carrier protein 0.7531253822127926 1.7536011213974187 0.0794988787487227 0.999997751884964 0.2547208972152953 8 Q86VD7,Q70HW3 2 +replication origin binding protein 0.7037637897469056 1.7081402581681666 0.0876103204943417 0.999999439833458 0.2645157753386855 3 Q13416,Q9UBD5 2 +non-motor microtubule binding protein 0.6018592754832631 1.6435124297899342 0.1002769557532476 0.9999999376138028 0.2811887719311516 13 Q15555,Q15691,Q96CW5,O94901,Q9ULW0,P60520 6 +extracellular matrix protein 0.6894873458792978 1.6434172570839294 0.100296632026398 0.9999999378276392 0.2811887719311516 3 Q9UFC0,P07942 2 +oxidase 0.5687665816145279 1.594431294592382 0.1108394677903561 0.999999990230152 0.2900299407180985 14 P13073,O43819,Q8NB78 3 +centromere DNA-binding protein 0.5890366526110866 1.5563909824490263 0.1196151481850926 0.9999999979413045 0.307861938771468 2 Q03188 1 +translation initiation factor 0.412868206038917 1.477359411484039 0.1395793201033046 0.9999999999438174 0.3489598940524931 39 O15372,Q9Y262,P60228,P55010,Q01085,O15371,O75153,O75822,P23588,Q86U42,P05198 11 +aspartic protease 0.5669802140771898 1.4422121454019938 0.1492425353322106 0.999999999990461 0.3604781238024165 2 Q8TCT9 1 +tubulin 0.6304347826086956 1.3734110658166792 0.1696245915837879 0.9999999999997882 0.4035009224038592 3 P07437,Q9BUF5 2 +phosphatase modulator 0.6768738321015006 1.249815390064934 0.2113669927865531 1.0 0.4545838064039567 5 Q8TF05 1 +transmembrane signal receptor 0.6495583751680866 1.2109898794422118 0.2258992834888507 1.0 0.4669396321684723 7 Q99720,Q8WUJ1 2 +protein modifying enzyme 0.4274480308007438 1.1729272277413598 0.2408249897237611 1.0 0.4786015618560821 23 O60476,P26572,Q15102,Q02809,Q86X55,Q12797,O14744,O15294,P51812,P13674,O60725,O00469,O60678 13 +oxygenase 0.6262002723628016 1.1100413878870985 0.2669811921790141 1.0 0.5239505896513154 7 P09601 1 +general transcription factor 0.3857583561389303 1.0199084735704769 0.3077718704534651 1.0 0.5842356641422906 29 Q6PD62,P23193,Q16625,Q71SY5,P55199,Q9Y5Q9,O95163,Q15648,P35269,Q9Y5Q8,Q15369,O60244,Q9UKN8 13 +protease 0.3493857046113809 0.895749899495626 0.3703863532480307 1.0 0.6706091660247596 38 P28074,P20618,Q9H4L4,P61009,P49721,P28070,Q9BT78 7 +DNA-directed RNA polymerase 0.4365964952005648 0.8938876450685959 0.371382008824721 1.0 0.6706091660247596 15 O00411,O15514,O15160,O14802,P19387 5 +esterase 0.5392398307130856 0.8882259038711775 0.3744192474676477 1.0 0.6706091660247596 9 Q8IY17 1 +oxidoreductase 0.3279804876186272 0.868624947880208 0.3850523042959186 1.0 0.671702353049547 48 O43676,O95168,Q8N4Q0,O15254,O96000,Q8N0U8,O43169,O95831,Q16718,P23368 10 +non-receptor serine/threonine protein kinase 0.3227950434274494 0.6498308988005896 0.515801457641273 1.0 0.8263349882620395 36 P42345,P31751,O60566,Q13131,P78362,P48729,Q13555,P19525,P24941,Q96KB5,P50750,O14757,P11802,Q00535,Q13418 15 +SNARE protein 0.4086820082986574 0.5989874901899293 0.5491812267534237 1.0 0.8374061068904315 13 O14653,O95249,O43752 3 +DNA-directed DNA polymerase 0.4974315560722173 0.5809630867844623 0.5612653321609764 1.0 0.8379139825048358 7 P40938,P56282,P49005,Q14181 4 +amino acid transporter 0.5075804063417317 0.5749806009357629 0.565304416847074 1.0 0.8379139825048358 4 O60831 1 +ATP-binding cassette (ABC) transporter 0.4188069497060502 0.508560338287009 0.611060435421271 1.0 0.8642926879381941 11 Q8NC96,Q03518 2 +calmodulin-related 0.3697525209416283 0.4878039019054493 0.6256887473576069 1.0 0.8761124291436071 14 Q9BRK5,Q14257,O43852 3 +transcription cofactor 0.3882186217059114 0.4403959905017913 0.6596503283653856 1.0 0.889794863174533 12 Q6P2C8,Q9HCD5,Q99417 3 +ligase 0.3088174394468626 0.4349364411053192 0.6636085626706094 1.0 0.889794863174533 26 Q9P2R7,P33121,A1L0T0,Q9UKU0,P30520 5 +protein phosphatase 0.3565620377783045 0.4278463101880163 0.6687630181821331 1.0 0.889794863174533 14 Q99956 1 +translation factor 0.4489092505859761 0.3812951740357425 0.7029842342345607 1.0 0.9014066063215066 6 P51114 1 +scaffold/adaptor protein 0.2581457199728899 0.3441712611699283 0.7307174938101275 1.0 0.91778117222552 75 Q96RT1,Q8IZ81,Q9UBB6,Q9UQB8,Q8TDW0,Q8N1F8,Q96F07,Q9Y679 8 +DNA metabolism protein 0.2650696497177137 0.2901121448946421 0.7717304448850568 1.0 0.9387501718865382 37 Q9BQ61,P25205,Q12824,Q5TKA1 4 +guanyl-nucleotide exchange factor 0.4144168352884682 0.2828275171659573 0.7773090595238852 1.0 0.9387501718865382 6 Q92538,Q96N67,Q7Z3U7 3 +kinase 0.2994384606482639 0.2600967551923488 0.7947891407982 1.0 0.9453173871614954 16 Q8TBX8,Q9BRR6,Q9HA64,Q9NVE7,O75414 5 +RNA methyltransferase 0.3052205676274444 0.2327877361015606 0.8159262365155127 1.0 0.9542928060336632 14 Q08J23,O75648,Q7Z2T5 3 +membrane trafficking regulatory protein 0.2880550963747078 0.2215534884590024 0.8246614934228895 1.0 0.9542928060336632 16 Q8WTV0,O43760,Q9NRW7,P24390,O00471,O43731 6 +microtubule binding motor protein 0.2767023855855304 0.2085785972580424 0.834777219999771 1.0 0.9542928060336632 17 P52732,O75935 2 +kinase modulator 0.3702945459518955 0.1813836200736315 0.8560664749178573 1.0 0.9599201193478571 6 Q99570,P54619,P67870 3 +exoribonuclease 0.3432210850977932 0.1796356637940493 0.8574386044335227 1.0 0.9599201193478571 9 Q96B26 1 +major histocompatibility complex protein 0.3205344827207926 0.165935123572965 0.8682080060343678 1.0 0.9599201193478571 3 P04439 1 +DNA helicase 0.2926007142687715 0.1252134631939634 0.9003545590417639 1.0 0.9672626737541946 11 P46063,Q96RR1 2 +cytoskeletal protein 0.3364728808054639 0.1239930824145935 0.9013207522297046 1.0 0.9672626737541946 6 P27105,Q14141,Q16181,Q9NVA2,Q9UHD8 5 +translation elongation factor 0.2710706150341686 0.1066035942106531 0.9151034670690472 1.0 0.9672626737541946 12 Q15029,P13639,O00178,O43324,P29692,Q7Z2Z2,Q9UG63,Q8NE71,P24534,Q969S9,P43897 11 +nucleotide kinase 0.2703709904179797 0.1055831570015641 0.9159130888107838 1.0 0.9672626737541946 12 P04183,Q13126,Q16854,Q14558 4 +non-motor actin binding protein 0.208582539617694 0.084845698142634 0.9323840626335896 1.0 0.975190368699694 25 Q9UEY8,Q99439,P60981,Q14651,P35611,P35080,P55196 7 +actin or actin-binding cytoskeletal protein 0.214146023468054 0.0778819633771197 0.937921946965948 1.0 0.975190368699694 17 Q6WCQ1,Q15942,P35241,Q9UHB6,P14649,Q01518,O75340,O15145,Q96HC4,P15311,P26038,P28289,O00151,P59998,P60660,Q9NYL9 16 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..aa1940407bf90d1018cfe835e315d37117c9f74c --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "C4 zinc finger nuclear receptor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "storage protein", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "zinc finger transcription factor"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGPAT1", "AGPAT5", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC7", "ANGEL1", "ANKFY1", "ANLN", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APLP2", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARID3B", "ARL1", "ARL6IP5", "ARPC1A", "ARPC3", "ARPC4", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD5", "ATG3", "ATL2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "AURKA", "AURKB", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BAP18", "BCAP29", "BCAP31", "BCAS2", "BCAT2", "BCKDHA", "BCKDHB", "BCLAF1", "BLM", "BLMH", "BLVRA", "BOP1", "BPHL", "BRCA1", "BRD1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX8", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKN2AIP", "CEBPZ", "CENPC", "CEPT1", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHDH", "CHEK1", "CHERP", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNP", "COA1", "COA3", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSE1L", "CSGALNACT2", "CSNK1A1", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBT", "DCAF13", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DDT", "DECR1", "DECR2", "DEK", "DENR", "DERL1", "DERL2", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC25", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERH", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESCO2", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FAM3C", "FAM98A", "FAM98B", "FARS2", "FARSA", "FARSB", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDE1", "GDI2", "GDPD1", "GFM2", "GGH", "GID8", "GLA", "GLB1", "GLB1L2", "GLDC", "GLMN", "GLO1", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLT1B", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HM13", "HMGA1", "HMGCL", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATIP2", "HTRA2", "HUWE1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPAD1", "IMPDH2", "ING5", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "ISCU", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LENG8", "LETM1", "LETMD1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A2", "MAPK1", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "METTL16", "METTL7B", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKRN2", "MMAB", "MMS19", "MOGS", "MON2", "MORF4L1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKIPSD", "NCOA5", "NCOR1", "ND1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4L", "NENF", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NKTR", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA1", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN3", "NSUN4", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC6", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPN1", "PAFAH1B3", "PAFAH2", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PARN", "PARP1", "PARP2", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHC2", "PHF10", "PHF3", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PICALM", "PIGL", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2B", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN9", "PUF60", "PURA", "PUS1", "PWP1", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABAC1", "RAC1", "RACGAP1", "RAD23B", "RAD51C", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM26", "RBM27", "RBM34", "RBM4", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIPK1", "RNASEH2A", "RNF2", "RNMT", "RNPS1", "RP2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35A3", "SLC35B2", "SLC37A4", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPCS2", "SPCS3", "SPEN", "SPOP", "SPOUT1", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAT1", "STAT3", "STK11IP", "STOM", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TADA3", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", 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sha256:e648ac9e480d90baab615a37b5ba8f95e0c613367466d69a02628a7c31d43eb9 +size 129454 diff --git a/pharos_dto/consensus.joblib b/pharos_dto/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3511f4c01c0b787fd563de6fe819784a5f5c8f2a --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:328ebd9f6f09e153bf34d775ba30859bdf4f6f3a770cec446e2c774ccc72abd1 +size 681335 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bf7cf34e1a291d8627385b8c806345ab93835528 --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Oxidoreductase 19 120 3.099333478897026 0.0019395657358804 26.983009708737864 113.91747572815534 0.6392672411957 0.4324241122550336 10.483097938966514 7.235161275092307 1.3581321831066435 0.3819609334162012 5.248714565109438e-05 0.0004869228837539 3.644502704472419e-05 0.0002035226796697 0.0006488150058568 +Dehydrogenase 6 61 2.8154517546794167 0.0048708709846856 14.00485436893204 56.08009708737864 -0.4370363771193292 0.4692872079440394 7.431563212064344 3.4983896420583886 1.174195224675972 0.3512016895000671 0.0047533286028669 0.0012207780133923 0.0003686013375342 0.0026808363995447 0.0213189468590221 +Translation initiation factor 8 18 2.3667368110362133 0.017945689400689 5.283980582524272 20.803398058252423 0.4565236500219777 0.559881468182603 3.9896024669487 1.082826267249171 0.8934418568512774 0.3359596376002439 1.0 0.1263420182810564 0.239336332644921 0.1486468007453543 0.0457284836366409 +F-type and V-type ATPases 4 16 2.088326582000765 0.0367683851886218 4.995145631067961 15.616504854368932 0.6819760311565471 0.3553057475304781 2.5561606009064737 1.187932616128487 1.149561543758102 0.2999604229905949 1.0 0.1049896535105009 0.2012104780589677 0.017764157863851 0.0044460825905537 +Translation factor 8 23 2.06428366110861 0.038990829247361 6.951456310679611 26.34223300970874 0.3217105737724597 0.5885494153132408 5.03989644056169 1.243180568658069 0.9262525781273792 0.3373319193546022 1.0 0.1755724648168266 0.3236452024265956 0.2555664496894125 0.1302255468206177 +G-protein modulator 8 24 2.0528021591962213 0.0400917690540967 8.04126213592233 28.50728155339806 -0.2094783886477757 0.5711042052390932 4.6920451540241235 4.6181832880357545 0.9500688649224748 0.3221198034539055 1.0 1.0 0.7182337894395352 0.8276076075029822 0.882446396892707 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..eb30e45d99879f1e891a6e16deb743bbb1d0f786 --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 1944, + "title": "Average number of proteins per term", + "value": 3.1347736625514404 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..fed2fc5c507e6e83cc39234304c3d0183b31499f --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b9c9de47d709a0c42d215ae200f03d596c22f03f --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,76 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Oxidoreductase 0.4368304523034925 3.099333478897026 0.0019395657358804 0.9770440268227272 0.0051090999871974 120 P11310,Q15392,P49419,P03886,Q8N4Q0,Q16718,P30837,Q9H9P8,P00374,Q8TED1,Q8N0U8,O95168,O15254,Q13423,O95831,Q14739,O43819,Q96CU9,Q9P0J0 19 +Dehydrogenase 0.4917739092787035 2.8154517546794167 0.0048708709846856 0.9999245552099836 0.010030691943039 61 P30837,P49419,P03886,Q8N4Q0,Q13423,O95831 6 +Translation initiation factor 0.6366057910774461 2.3667368110362133 0.017945689400689 0.9999999999999994 0.028329496808089 18 Q9Y262,P60228,P55010,O15371,O75153,O75822,P23588,P05198 8 +F-type and V-type ATPases 0.6190697057814577 2.088326582000765 0.0367683851886218 1.0 0.0506017357150423 16 P00846,Q9Y5K8,Q9Y487,P56134 4 +Translation factor 0.550862237947682 2.06428366110861 0.038990829247361 1.0 0.0529316843972555 23 Q9Y262,P60228,P55010,O15371,O75153,O75822,P23588,P05198 8 +PIKK family 0.6882906260136142 2.0598963161094943 0.0394084539691439 1.0 0.0533496062089246 2 P42345 1 +G-protein modulator 0.5415251958901394 2.0528021591962213 0.0400917690540967 1.0 0.0541241051833279 24 Q6WCQ1,Q96N67,O00410,Q96D71,Q14C86,Q96F07,Q13576,Q7L576 8 +SLC superfamily of solute carriers 0.417514106465686 1.9118598851139803 0.0558941681794027 1.0 0.0701817743290514 53 P30825,Q96NB2,Q86VD7,O43772,Q9BQT8,Q9Y619,Q70HW3,Q8IXU6,Q9BSK2,O43808,Q8WWI5,Q9HC07,Q6N075,Q8TBP6,O00400,Q15758,P41440,Q6P1Q0 18 +SLC25 family of mitochondrial transporters 0.522057915754968 1.911228033889158 0.0559752827412824 1.0 0.0702038384832601 24 O43772,Q9BQT8,Q70HW3,O43808,Q9BSK2,Q8TBP6,Q86VD7 7 +Phosphatase inhibitor 0.7420506164827916 1.88024157994846 0.0600751611598204 1.0 0.0744334692764123 3 Q92688,P55209 2 +Transporter 0.3262135475347849 1.8710698291681351 0.0613354028310069 1.0 0.0757054114942713 198 Q9Y5K8,P61619,Q96EE3,O43772,P51809,Q96ES6,Q70HW3,Q9NRW7,Q8IXU6,O43752,O43808,Q8WWI5,Q9BSK2,Q9Y487,Q9Y619,Q8TBP6,P00846,Q15758,P41440,Q9UI14,Q9Y3B3,Q6P1Q0,P30825,Q9NUT2,O14653,Q9UHQ4,Q9HC07,O00400,Q93050,Q9BRK0,Q12907,P98194,Q9BQT8,Q8TB61,Q13277,O43760,Q6N075,P24390,O00471,Q86VD7,Q03518,Q96NB2,Q8N2H4,O95249,Q9Y5P4,P56134,Q15070,O96008 48 +F-type ATPase 0.767645457780376 1.817978154678902 0.069067471718766 1.0 0.083343988219293 8 P00846 1 +Phosphatase 0.5005874375169695 1.7832528990140653 0.0745451448881218 1.0 0.0886191101417813 25 P30154,Q8TF05,Q9H0C8,Q9NPH0,Q9C0I1,Q13614,Q9BX68,Q5TFE4 8 +Signaling 0.5415437216488947 1.7595036725261857 0.0784919970123541 1.0 0.0925198128528161 18 Q5JRA6,Q8WUJ1,Q8IZ81,Q9UHD1,Q07812,P43490,P51858,Q96PC5 8 +SRC family 0.6243918261433647 1.73797925959589 0.0822144683816714 1.0 0.0960486337343565 2 P07948 1 +Mitochondrial nucleotide transporter subfamily 0.6869100896734255 1.7120054347989664 0.0868956669047973 1.0 0.1003118625076757 10 Q86VD7,Q70HW3,O43808 3 +Replication origin binding protein 0.7037637897469056 1.7081402581681666 0.0876103204943417 1.0 0.1010168819934758 3 Q13416,Q9UBD5 2 +Cell-cell junction 0.6925411827352619 1.6572845379365244 0.0974619618642815 1.0 0.1104176669068735 3 Q16625 1 +Tight junction 0.6925411827352619 1.6572845379365244 0.0974619618642815 1.0 0.1104176669068735 3 Q16625 1 +CDK family 0.7575762442270909 1.5839957558851971 0.1131946849127381 1.0 0.1247451629650583 5 P11802,P24941,P50750 3 +Epigenetic regulator 0.4349496321686038 1.533764719655647 0.1250875453408664 1.0 0.1350195381136281 34 Q15059,Q8NB78,Q9H7B4,Q96JM7,P83916,P25440,Q86X55,Q96KQ7,Q13547,Q16637,O96028,Q9H9B1 12 +Guanyl-nucleotide exchange factor 0.662755796224531 1.5215687803470757 0.1281171650907764 1.0 0.1378305306787323 3 Q96N67 1 +Kinase activator 0.6540038826318224 1.481521371725829 0.1384676941743321 1.0 0.1479017568543415 3 P14635 1 +Growth factor 0.7267030544209289 1.456461582534134 0.145265062335532 1.0 0.1550770352445218 5 P51858,Q5JRA6 2 +Oxidase 0.4876607405482827 1.4455986051224337 0.1482898181214316 1.0 0.1582192131877404 19 P11310,O15254 2 +Receptor 0.4510716800395405 1.4386816977035872 0.1502407271971841 1.0 0.1602128215421426 26 Q9UQB8,Q13432,A6NIH7,Q567V2 4 +AMPK subfamily 0.5559519948102413 1.384952773401118 0.1660669085777586 1.0 0.1766050712665004 2 Q13131 1 +Polymerase 0.4559300222474753 1.379450603406542 0.1677558662911324 1.0 0.1783036654291752 23 P40938,P62487,Q9NRG0,P49005,O00411,Q9NR33,O15160,O14802,P56282,P19387 10 +Tubulin 0.6304347826086956 1.3734110658166792 0.1696245915837879 1.0 0.180191369420155 3 P07437,Q9BUF5 2 +Non-motor microtubule binding protein 0.5915742220621771 1.3466118249216028 0.1781052837301016 1.0 0.1887877162329975 11 P60520,Q15555,Q96CW5,Q9ULW0,O94901 5 +Mutase 0.5426532598118623 1.315821445972351 0.1882339793907124 1.0 0.1993065664136954 2 P00492 1 +CAMKL family 0.6804816445754602 1.2568381498562735 0.2088122485956094 1.0 0.2208547395374672 4 P54619,O14757 2 +Extracellular structure 0.6201575033118198 1.1563749124936058 0.2475278386208799 1.0 0.2615185425429296 8 Q96CW1,Q32P28,Q5KU26,Q92791,Q9Y2T2,O43290 6 +CAMK group 0.6492167184764117 1.1433077517724328 0.2529108376667879 1.0 0.2669156723258608 6 P54619,Q13555,O14757 3 +Small GTPase 0.4207640276208741 1.1248197735427294 0.2606654135705688 1.0 0.2749503874016201 23 Q14141,Q8IXI1,P63000,P50570,O75616,Q96P70,Q9UI26,O60313,P61586,O95373 10 +Phosphatase modulator 0.6410959125173268 1.1018251935106342 0.2705376753516173 1.0 0.2852089158804469 5 Q92688,P55209 2 +Writer 0.5196132985422269 1.0775508748548064 0.2812342352877501 1.0 0.2963248527909953 12 Q96KQ7,Q9H7B4,Q86X55,Q9H9B1 4 +DNA helicase 0.4975375420390952 1.0642400189528496 0.2872199822539421 1.0 0.3019770932945718 13 P25205 1 +Protein arginine methyltransferase 0.6176566049983812 1.0000564022721472 0.3172832132353633 1.0 0.3330445823593662 4 Q86X55,O14744,O60678 3 +Protein methyltransferase 0.5226193469571075 0.9958416907412472 0.3193270701045438 1.0 0.3350090794836661 11 Q96KQ7,Q9H7B4,Q86X55,Q9H9B1 4 +Protein phosphatase 0.5274817220681648 0.9320298079318154 0.351321120968644 1.0 0.3679785879111228 10 Q8TF05,Q9H0C8 2 +DNA-directed DNA polymerase 0.5272472772161688 0.9309093875126132 0.3519004381305044 1.0 0.3683868883821758 10 P40938,Q9NRG0,P49005,Q9NR33 4 +Reductase 0.4274933244631988 0.9081510158943006 0.363798440033154 1.0 0.3804325806479028 16 Q14739,Q15392,O95168 3 +Esterase 0.4856530903670596 0.900501126971674 0.3678536258440281 1.0 0.3842597789579746 12 Q8IY17 1 +Mitochondrial amino acid transporter subfamily 0.5709403096792227 0.8749455571958866 0.3816035292845665 1.0 0.3984088404560673 7 O43772 1 +V-type ATPase 0.5550666623600337 0.8684285704138098 0.38515975991724 1.0 0.4016902217162632 8 Q9Y5K8,Q9Y487 2 +G-protein 0.3485590460903316 0.7508093780249152 0.4527673846915905 1.0 0.4706843828023807 30 Q14344,Q14141,Q8IXI1,P63000,P50570,Q9NTK5,P08754,O75616,Q96P70,Q9UI26,O60313,P61586,O95373 13 +Helicase 0.3677207089585618 0.7295711431750876 0.4656523664330017 1.0 0.483562072834271 22 P42694,Q14562,Q96RR1,P25205,P46063,Q96S55 6 +Metalloprotease 0.3345081378085203 0.7206357067140869 0.4711336789197933 1.0 0.4889929908275911 35 Q9NZ08,P55786,O43847,Q10713,P52888,Q7Z2K6,Q9BYT8 7 +DNA-directed RNA polymerase 0.4483123251290636 0.7129361409046511 0.4758852739377213 1.0 0.4934348340054437 12 P19387,O15160,O14802,O00411 4 +Ubiquitin-protein ligase 0.4045725564253216 0.7128785017743967 0.4759209432922875 1.0 0.4934348340054437 15 Q96PU5,Q96J02 2 +Ca2+-ATPases 0.5435645481934972 0.7079008643380712 0.4790068229382553 1.0 0.4963695435991302 4 P98194,P20020 2 +Bromodomain 0.5112972472940249 0.6835528054124514 0.4942575948480194 1.0 0.5119002474078582 8 Q15059,P25440 2 +Transcription cofactor 0.3817130573094637 0.6433084690032599 0.5200239620447062 1.0 0.5380130826050606 16 O60244,Q99417,Q6P2C8 3 +Ligase 0.2877897557655279 0.6261484526669642 0.5312175740353584 1.0 0.5484264280003912 70 Q9P2R7,Q96PU5,P33121,Q9H1A4,Q96J02,O95363,Q9UKU0,P30520,Q9NSE4 9 +SLC35 family of nucleotide sugar transporters 0.4584968584963538 0.6072806291236308 0.5436646913682088 1.0 0.560383966076245 3 Q8IXU6 1 +SNARE protein 0.4210614076410592 0.5836594681426075 0.5594494418596891 1.0 0.5760432812368833 12 O14653,O95249,O43752 3 +ABCB subfamily 0.5070941998558423 0.5776068760786134 0.5635295635576023 1.0 0.5799372533382631 6 Q03518 1 +Miscellaneous SLC25 mitochondrial transporters 0.3950697372688924 0.5759713269202236 0.5646345624844813 1.0 0.5807669785554664 2 Q9Y6C9 1 +Membrane trafficking regulatory protein 0.3516582239759187 0.5349667108231799 0.5926728766855431 1.0 0.6089619832329259 17 Q96EE3,O60749,O43760,Q9NRW7,P24390,O00471,O43731 7 +Nucleotidyltransferase 0.3160345022905008 0.5255616016714301 0.5991928418218027 1.0 0.6153359136299971 30 P62487,Q9NRG0,P49005,O00411,Q9NR33,O15160,O14802,O43252,P19387 9 +Nucleotide phosphatase 0.4393316164160424 0.4112791795320886 0.6808678346343915 1.0 0.6948068611702136 8 O43681,P49902,Q9BX68,Q5TFE4 4 +Exoribonuclease 0.4110223545499974 0.3672112537575736 0.7134614455423409 1.0 0.7261618063530423 9 Q96B26,Q9NQT5 2 +Decarboxylase 0.4325613831360972 0.3320884295363799 0.7398224867281917 1.0 0.7525980712713787 4 A1L0T0 1 +Other group 0.3611972645804683 0.2577573555212767 0.7965941779426999 1.0 0.807392639166115 10 Q99570,O60566,O14976,Q96KB5 4 +ATP-binding cassette transporter family 0.3818858529477091 0.2400867384354113 0.8102630147869183 1.0 0.820818812269812 8 Q03518 1 +Enzyme modulator 0.2372041496273874 0.2069202312878831 0.8360721561516811 1.0 0.8460767691061836 99 O00410,Q7L576,Q99733,Q6WCQ1,Q14141,Q14344,P63000,P50570,O95163,O75616,Q9UI26,Q15369,P61586,Q92688,P14635,P08754,Q5VZL5,Q96N67,Q14C86,Q96F07,Q96P70,Q13576,Q9UJZ1,Q92616,O95373,Q8IXI1,Q9NTK5,Q96D71,P46060,Q8N1F8,O60313,P46379,P53367,P55209 34 +CMGC group 0.3196807885878345 0.2060815538862358 0.8367272073769565 1.0 0.8460767691061836 12 P78362,P11802,P24941,P50750 4 +Transaminase 0.351067610460575 0.1706439723215327 0.8645037200820385 1.0 0.8725831941014968 8 Q8TD30,O15269 2 +AGC group 0.351703348047325 0.1582111039472983 0.8742904542692029 1.0 0.8820034473789987 7 P31751 1 +CK1 group 0.3147306943543095 0.1543298672878897 0.8773496487268815 1.0 0.8846305586748223 3 P48729,Q99986 2 +Oxygenase 0.3332388673970813 0.1196210851540735 0.9047833161207408 1.0 0.910403088270559 5 Q02809,Q16850,O00469 3 +Microtubule family cytoskeletal protein 0.1970680335207977 0.0796125801620875 0.936545389455398 1.0 0.9394449107849814 32 P60520,P52732,Q15555,Q9Y6G9,O43264,Q15691,Q13561,Q96CW5,Q9ULW0,O94901 10 +Immune response 0.2838583955829887 0.0683785238953025 0.9454843172590052 1.0 0.9474337694595392 6 P78318,Q9NUQ3,Q9NX40,Q6AI08,Q6P2E9 5 +Non-motor actin binding protein 0.1868162518600876 0.0585080687424751 0.9533439355794509 1.0 0.9543257521969374 22 Q9UEY8,Q99439,P35611,Q14651,P55196,P28289 6 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b2ef629e2b5228a01a25ea72a3e0981a4e805d32 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2,4-dienoyl-CoA reductase, mitochondrial", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L41, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-aminobutyrate aminotransferase, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-1", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-methylcytosine rRNA methyltransferase NSUN4", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-1 complex subunit sigma-2", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family B member 8, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family D member 4", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase WRNIP1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "AUR family", "Abl interactor 1", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A synthetase 2-like, mitochondrial", "Acetyl-coenzyme A transporter 1", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Activating signal cointegrator 1", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine aminotransferase 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amyloid-like protein 2", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Anion exchange protein 2", "Anion exchangers", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Antigen peptide transporter 2", "Apoptosis regulator BAX", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arginase-2, mitochondrial", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical group", "Aurora kinase a", "Aurora kinase b", "B-cell receptor-associated protein 29", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2 homologous antagonist/killer", "Bcl-2-associated transcription factor 1", "Beta-galactosidase", "Beta-galactosidase-1-like protein 2", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 3", "Bromodomain-containing protein 4", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CDKN2A-interacting protein", "CHK1 subfamily", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CMGC group", "COMM domain-containing protein 5", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "COUP-TF-like receptors", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carbonyl reductase family member 4", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Cat eye syndrome critical region protein 2", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere protein C", "Centromere/kinetochore protein zw10 homolog", "Chaperone", "Chaperonin", "Charged multivesicular body protein 6", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Choline dehydrogenase, mitochondrial", "Choline transporter-like protein 1", "Choline/ethanolaminephosphotransferase 1", "Chondroitin sulfate N-acetylgalactosaminyltransferase 2", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 2", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 4", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collagen type IV alpha-3-binding protein", "Collectin-12", "Condensin complex subunit 1", "Copper-transporting ATPase 1", "Copper-transporting ATPase 2", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1C", "Coup transcription factor 2", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cu+-ATPases", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystatin-B", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DCK/DGK family", "DDB1- and CUL4-associated factor 13", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA topoisomerase 3-alpha", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(14)-sterol reductase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxyguanosine kinase, mitochondrial", "Deoxyribonuclease-2-alpha", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Derlin-2", "Desmocollin-1", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Dna-dependent protein kinase catalytic subunit", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase ZNF598", "EF-hand domain-containing protein D1", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER lumen protein-retaining receptor 3", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "ERO1-like protein beta", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endonuclease III-like protein 1", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 7", "Epidermal growth factor receptor substrate 15", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Estradiol 17-beta-dehydrogenase 8", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 1", "Exocyst complex component 3", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 6B", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferritin light chain", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Folate transporter 1", "Fragile X mental retardation syndrome-related protein 1", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "GC-rich sequence DNA-binding factor 2", "GDP-fucose protein O-fucosyltransferase 2", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General vesicular transport factor p115", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate exchanger SLC37A4", "Glucose-6-phosphate isomerase", "Glucose-induced degradation protein 8 homolog", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase catalytic subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--tRNA ligase", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi SNAP receptor complex member 2", "Golgi pH regulator family", "Golgi ph regulator b", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "H/ACA ribonucleoprotein complex subunit 3", "HBS1-like protein", "HDAC class I", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histidine triad nucleotide-binding protein 3", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase NSD3", "Histone-lysine N-methyltransferase SETD2", "Histone-lysine N-methyltransferase SMYD3", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "ILK subfamily", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of growth protein 5", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 3", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF18B", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIFC1", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LETM1 domain-containing protein 1", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Legumain", "Lethal(3)malignant brain tumor-like protein 3", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophosphatidylcholine acyltransferase 2", "Lysophospholipid acyltransferase 5", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "M-phase phosphoprotein 8", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAPK family", "MBT domain", "MCU family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB", "Mediator of RNA polymerase II transcription subunit 12", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 20", "Mediator of RNA polymerase II transcription subunit 25", "Mediator of RNA polymerase II transcription subunit 27", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine--tRNA ligase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Methyltransferase-like protein 7B", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial coenzyme A transporter SLC25A42", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import inner membrane translocase subunit Tim22", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multifunctional protein ADE2", "Muscleblind-like protein 1", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light chain 6B", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 12", "Myotubularin-related protein 2", "N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 50", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral cholesterol ester hydrolase 1", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear cap-binding protein subunit 2", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor", "Nuclear receptor coactivator 5", "Nuclear receptor corepressor 1", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase 6", "Nucleoside diphosphate kinase A", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "OCIA domain-containing protein 1", "Obg-like ATPase 1", "Occludin", "Origin recognition complex subunit 2", "Origin recognition complex subunit 3", "Origin recognition complex subunit 6", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P53-like transcription factor", "PAKB subfamily", "PAX3- and PAX7-binding protein 1", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PKC alpha subfamily", "PKC family", "PKN family", "PLK family", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 3", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal 2,4-dienoyl-CoA reductase", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal bifunctional enzyme", "Peroxisomal biogenesis factor 19", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phenylalanine--tRNA ligase, mitochondrial", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 3-kinase regulatory subunit beta", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylated adapter RNA export protein", "Plasma membrane calcium-transporting ATPase 1", "Plasma membrane calcium-transporting ATPase 4", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Platelet-activating factor acetylhydrolase 2, cytoplasmic", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polyhomeotic-like protein 2", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Pre-mRNA cleavage complex 2 protein Pcf11", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Prenylated Rab acceptor protein 1", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX37", "Probable E3 ubiquitin-protein ligase makorin-2", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable cysteine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable helicase with zinc finger domain", "Probable histidine--tRNA ligase, mitochondrial", "Probable leucine--tRNA ligase, mitochondrial", "Probable ribosome biogenesis protein RLP24", "Probable serine carboxypeptidase CPVL", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein NDRG3", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein S100-A13", "Protein SCAF8", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SYS1 homolog", "Protein Wiz", "Protein XRP2", "Protein angel homolog 1", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein gpr107", "Protein kinase", "Protein kinase c alpha type", "Protein kinase c beta type", "Protein lin-9 homolog", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1G", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein transport protein Sec23A", "Protein transport protein Sec23B", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog A", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pterin-4-alpha-carbinolamine dehydratase", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RIPK family", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA polymerase II elongation factor ELL", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein FUS", "RNA-binding protein Nova-1", "RNA-binding protein with serine-rich domain 1", "RNA/RNP complex-1-interacting phosphatase", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor beta", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein R-Ras2", "Ras-related protein Ral-A", "Reader", "Receptor", "Receptor expression-enhancing protein 2", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Recombining binding protein suppressor of hairless", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinoic acid-induced protein 1", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal RNA-processing protein 7 homolog A", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "Ribosome-releasing factor 2, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "SAP30-binding protein", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC33 acetylCoA transporter", "SLC35 family of nucleotide sugar transporters", "SLC37 family of phosphosugar/phosphate exchangers", "SLC4 family of bicarbonate transporters", "SLC44 choline transporter-like family", "SLC5 family of sodium-dependent glucose transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC61 Molybdate transporter family", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STE group", "STE20 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Secretory carrier-associated membrane protein 4", "Sentrin-specific protease 3", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 11-interacting protein", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase chk1", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters", "Sodium-dependent HCO3- transporters", "Sodium-dependent multivitamin transporter", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 9", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 25 member 33", "Solute carrier family 25 member 40", "Solute carrier family 25 member 44", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 23", "Syntaxin-10", "Syntaxin-12", "Syntaxin-18", "Syntaxin-3", "Syntaxin-5", "Syntaxin-6", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "Syntenin-1", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TOPK family", "TP53-binding protein 1", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Testin", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Torsin-1A", "Torsin-1B", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription factor 20", "Transcription initiation factor IIB", "Transcription initiation factor TFIID subunit 9B", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor CTCF", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transducin-like enhancer protein 3", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation release factor", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 4", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Trypsin-3", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2B chain", "Tubulin beta-6 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase lyn", "Tyrosine-protein kinase yes", "Tyrosine-protein phosphatase non-receptor type 9", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP4", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm3", "U6 snRNA-associated Sm-like protein LSm4", "U6 snRNA-associated Sm-like protein LSm5", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "UDP-N-acetylglucosamine transporter", "UDP-glucose:glycoprotein glucosyltransferase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "UbiA prenyltransferase domain-containing protein 1", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 36", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Very long-chain acyl-CoA synthetase", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WEE family", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YLP motif-containing protein 1", "YSK subfamily", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCHC domain-containing protein 8", "Zinc finger E-box-binding homeobox 2", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 148", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein 644", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 5", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial", "tRNA pseudouridine synthase A"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG12", "ALYREF", "ANAPC1", "ANGEL1", "ANO6", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APLP2", "ARCN1", "ARFIP1", "ARG2", "ARHGDIA", "ARID3B", "ARPC1A", "ARPC3", "ARPC4", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATIC", "ATL2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "AURKA", "AURKB", "BAG6", "BAIAP2", "BAK1", "BAX", "BCAP29", "BCAP31", "BCAS2", "BCAT2", "BCKDHB", "BCLAF1", "BLMH", "BLVRA", "BOP1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIX1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC37", "CDC40", "CDC42", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKN2AIP", "CEBPZ", "CECR2", "CENPC", "CEPT1", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHDH", "CHEK1", "CHERP", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNP", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPOX", "CPSF1", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBT", "DCAF13", "DCPS", "DCTN1", "DCTN2", "DDB1", "DDI2", "DDOST", "DDT", "DECR1", "DECR2", "DENR", "DERL1", "DERL2", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIS3", "DLD", "DLST", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUSP11", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELL", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "EPHA7", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERH", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FAM177A1", "FARS2", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FOXRED1", "FSCN1", "FTL", "FUBP1", "FUBP3", "FUS", "FXR1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GCAT", "GCFC2", "GCLC", "GCN1", "GDI2", "GFM2", "GGH", "GID8", "GLB1", "GLB1L2", "GLDC", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNPDA1", "GNS", "GOSR1", "GOSR2", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPR107", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2F2", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HEATR1", "HEATR6", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HPRT1", "HSD17B10", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPAD1", "IMPDH2", "ING5", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "IVD", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LETMD1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LRRC47", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LYN", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A2", "MAPK1", "MAPRE1", "MAPRE2", "MARCH5", "MARS2", "MAT2A", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED12", "MED14", "MED20", "MED25", "MED27", "METTL7B", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MKRN2", "MMS19", "MORF4L1", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL14", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL38", "MRPL39", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL48", "MRPL49", "MRPL9", "MRPS11", "MRPS16", "MRPS18A", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA50", "NADK2", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCBP1", "NCBP2", "NCEH1", "NCL", "NCOA5", "NCOR1", "ND1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEDD4L", "NEK9", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA1", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN3", "NSUN4", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCLN", "OLA1", "OPA1", "ORC2", "ORC3", "ORC6", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "PAFAH2", "PAICS", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDHX", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF10", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIK3C2A", "PIK3R2", "PIK3R4", "PINX1", "PIP4K2C", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNP", "PNPLA6", "PNPT1", "POFUT2", "POGZ", "POLA2", "POLD2", "POLDIP3", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL3", "PPM1G", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA1", "PRKAA2", "PRKAG1", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2B", "PRRC2C", "PRSS3", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPN9", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "RAB3GAP2", "RABAC1", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIPK1", "RNASEH2A", "RNH1", "RNPS1", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "S100A10", "S100A11", "S100A13", "SAE1", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIN3A", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMN1*", "SMYD3", "SNAP23", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SPAG9", "SPCS2", "SPCS3", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAT1", "STAT3", "STK11IP", "STK26", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUPT16H", "SUPT6H", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM22", "TJP1", "TK1", "TKT", "TLE3", "TM7SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM165", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOP3A", "TOR1A", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRIP4", "TROVE2", "TRUB1", "TSFM", "TSG101", "TST", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA6", "UBE2L3", "UBIAD1", "UCHL5", "UGGT1", "UNC119", "UNC119B", "UPF1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP5", "USP7", "UTP11", "UTP14A", "UTP3", "UTP6", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VRK1", "VRK2", "WARS", "WDHD1", "WDR1", "WDR33", "WDR74", "WDR82", "WIZ", "WRNIP1", "XAB2", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS2", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZCCHC8", "ZEB2", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF148", "ZNF281", "ZNF598", "ZNF622", "ZNF644", "ZW10", "ZYX"], "leading_proteins": ["ABCB8", "ACADM", "ACOX3", "ACP6", "ACSL1", "ACSL6", "ADD1", "ADD3", "ADSS", "AFDN", "AIFM1", "AKT2", "ALDH1B1", "ALDH7A1", "ANAPC1", "ANP32B", "AP2M1", "AP3M1", "ARFIP1", "ASNA1", "ATP2B1", "ATP2C1", "ATP5J2", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "BAG6", "BAIAP2", "BAX", "BCAP29", "BRD2", "BRD3", "BUB1B", "CAMK2G", "CARM1", "CBX1", "CCNB1", "CDK2", "CDK4", "CDK9", "CHEK1", "CHORDC1", "CHRAC1", "CLUH", "CNN2", "COL4A3BP", "COLEC12", "CSNK1A1", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DCTN2", "DHCR24", "DHFR", "DHX8", "DNM2", "DOCK7", "DYNC1LI1", "EDC4", "EHMT1", "EHMT2", "EIF2S1", "EIF3D", "EIF3E", "EIF3J", "EIF3L", "EIF4B", "EIF5", "ELMOD2", "ELOC", "ELP1", "ERAL1", "ERAP1", "ERMP1", "EXOC5", "EXOSC3", "EXOSC8", "FARS2", "FOXRED1", "GABARAPL2", "GAK", "GAPVD1", "GCN1", "GNA13", "GNAI3", "GOSR1", "GOSR2", "GPT2", "GPX8", "HDAC1", "HDGF", "HEATR6", "HELZ", "HINT2", "HPRT1", "IARS2", "IGBP1", "ILKAP", "ILVBL", "IPO11", "IPO5", "IPO7", "IPO9", "IQGAP2", "ITCH", "KDELR1", "KDELR3", "KDM1B", "KIF11", "L2HGDH", "L3MBTL3", "LBR", "LETMD1", "LMAN2", "LYN", "MAPRE1", "MAPRE2", "MCM3", "MED14", "MED27", "MFSD3", "MFSD5", "MIA2", "MIA3", "MPRIP", "MPV17L2", "MTCH2", "MTMR12", "MTMR2", "MTOR", "MYCBP", "NAMPT", "NAP1L1", "NAP1L4", "ND1", "NDUFA13", "NDUFA5", "NDUFB4", "NEDD4L", "NLN", "NNT", "NPEPPS", "NRDC", "NSD2", "NT5C2", "NT5DC1", "OCIAD1", "OCLN", "OLA1", "OPA1", "ORC2", "ORC3", "OXA1L", "P3H1", "P3H4", "PAPSS1", "PBK", "PIK3R4", "PLOD1", "PLOD2", "PLS1", "PMPCA", "PNPLA6", "POLD2", "POLE2", "POLE4", "POLR1C", "POLR2C", "POLR2G", "POLR3A", "POLRMT", "PPP2R1B", "PPP4R1", "PRKAA1", "PRKAG1", "PRMT3", "PRMT5", "RABAC1", "RAC1", "RANGAP1", "RECQL", "REEP2", "REPS1", "RFC3", "RHOA", "RHOT2", "SART1", "SCO2", "SEC61A1", "SEH1L", "SEPT6", "SFXN2", "SLC19A1", "SLC1A5", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A33", "SLC25A40", "SLC25A42", "SLC33A1", "SLC35B2", "SLC35F2", "SLC44A1", "SLC7A1", "SMN1*", "SMYD3", "SNX2", "SPTLC1", "SRPK2", "STK11IP", "STOML2", "STX3", "STX6", "SUCLA2", "SUN1", "SYNGR2", "SYS1", "TAP1", "THOP1", "TMED7", "TMEM165", "TMOD1", "TOMM40", "TPX2", "TUBB", "TUBB6", "TUBGCP3", "TWNK", "TXLNG", "UNC119", "UNC119B", "VAMP7", "VKORC1L1", "VPS45", "VRK1", "WRNIP1", "ZADH2", "ZMYM4", "ZW10"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c2c9a89814544d67cab453c74790749979179bf3 --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..d77ad96a448fdbd4b2978e28f77aea3386e59921 --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2b632fe6a3dbc98b2f632eaa6cc340ec84b13081f18860ea35db06d114582ca9 +size 197484 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c4c8ea0916980a7727ada1e41a5e12e075ffc500 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tclin", "1": "Tbio"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b5793d33097db2645800d8020176410e051f5197 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7cca88da1fb9ed0f5cb48e20672ecfd06b18bbc6b7054f7104aa02e85cac4218 +size 133874 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..288bf643bb332b7e9bee7d1929781f1697b27894 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:630294905b47f35becfc6c4c0e900b7113b267dfb6aed38bbda917d50fc8fe85 +size 126565 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..97c03e4382746971b25e30fbf55649e37c2aac47 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bcc4e2a87988200f64baa320ecfc6f1a10628ce9012ee4ed39c83523e18d0e32 +size 68767 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..96582993f8f77009b01c26b2d1cd882759aee33a --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tclin 15 79 2.1648912501754 0.0303960144429993 19.366504854368937 86.39077669902913 0.9399778874953114 0.4805096456956057 6.659845213621253 7.009024167820235 0.9745051203556824 0.3806460486794667 0.0222316327167134 0.0877454489981553 0.0196574346423395 0.0423679846197404 0.0216455271302002 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6a6610d736eadabb4f3e5f5a2ea52071960905bb --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 771.0 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0a49da41fc1c44105dba1fb65f5afb4635f81351 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ddde07116c59117aeab5c9d6b41b7b711829544c --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tclin 0.4190288984775311 2.1648912501754 0.0303960144429993 0.116152031646264 0.1215840577719973 79 O43676,Q99720,P48735,P28074,P00374,P03886,P20618,O95168,P38435,O96000,Q14145,P49721,Q16718,Q9P0J0,P11802 15 +Tbio 0.1700585344144801 1.1616901345623232 0.2453613544655857 0.675693115783705 0.2453613544655857 2364 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464 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7d78b2d64934a664f202df478939daf364696f33 --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf35", "C1orf52", "C2CD5", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf33", "CAAP1", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC59", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPI", "CENPP", "CENPQ", "CENPU", "CENPV", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLK", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM114A2", "FAM120A", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM207A", "FAM208A", "FAM208B", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMC1", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LETMD1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM12", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "M6PR", "MACF1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NEPRO", "NES", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2B", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "ROMO1", "RP2", "RPA1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RSRC1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35A4", "SLC35B2", "SLC35F2", "SLC37A4", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPOP", "SPOUT1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THEM6", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THYN1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM29", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF3", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED8", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM19", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM223", "TMEM230", "TMEM245", "TMEM33", "TMEM41A", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBFD1", "UBIAD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "UROD", "USMG5", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZCCHC17", "ZCCHC3", "ZCCHC8", "ZDHHC20", "ZEB2", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF148", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF644", "ZPR1", "ZRANB2", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["AAR2", "AASDHPPT", "ABCB8", "ACADM", "ACBD3", "ACOX3", "ACP6", "ACSL1", "ACSL6", "ADD1", "ADD3", "ADPGK", "AFDN", "AIFM1", "AKAP8", "ALDH1B1", "ALDH7A1", "ALG1", "ALG13", "ALG2", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC5", "ANAPC7", "ANK3", "ANP32B", "ANXA4", "AP2A1", "AP2B1", "APOO", "ARID2", "ARL1", "ARMC1", "ARPC3", "ATAD3B", "ATP2C1", "ATP5J2", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP7B", "AUP1", "BAG2", "BAG4", "BAG6", "BAIAP2", "BCAP29", "BCKDHB", "BCLAF1", "BRI3BP", "BUB1B", "BZW2", "C17orf75", "C2CD5", "C3orf58", "CALU", "CAND2", "CBX1", "CCDC134", "CD2AP", "CD47", "CDCA5", "CDK4", "CDKAL1", "CDKN2A", "CENPI", "CENPP", "CHCHD3", "CHORDC1", "CHP1", "CIP2A", "CIRBP", "CLPP", "CLPTM1", "CLPTM1L", "CLSPN", "CLUH", "CNNM3", "COA1", "COG2", "COG5", "COG7", "COL4A3BP", "COPS4", "COX4I1", "COX6C", "CPSF2", "CTPS1", "CTR9", "CUL1", "CYB5B", "CYB5R1", "CYC1", "CYFIP2", "DCTN4", "DDRGK1", "DECR2", "DHCR24", "DHFR", "DHX8", "DNAAF2", "DNAJC10", "DNAJC3", "DNAJC7", "DOCK7", "DPM1", "DUSP9", "EFHD1", "EI24", "EIF3D", "EIF3J", "EIF5", "ELMOD2", "EPB41L3", "EPB41L5", "EPDR1", "ERBIN", "ERCC6L", "ERGIC3", "EXO1", "EXOC5", "EXOSC2", "EXOSC3", "EXOSC8", "FAM3C", "FANCD2", "FANCI", "FARP1", "FHOD1", "FKBP10", "FKBP14", "FKBP2", "FLAD1", "FLNC", "FN3KRP", "FOXK1", "FOXRED1", "FXR1", "GABARAPL2", "GBF1", "GDAP1", "GEMIN4", "GGCX", "GHITM", "GINS3", "GINS4", "GNA13", "GNPDA1", "GOSR1", "GOSR2", "GPAM", "GPT2", "GPX8", "GTF2F1", "GTPBP1", "HAT1", "HAUS4", "HCCS", "HDGF", "HELZ", "HINT2", "HLA-A", "HLTF", "HNRNPA3", "HNRNPAB", "HNRNPF", "HNRNPH3", "HOXD11", "HS2ST1", "HSD17B12", "HSPA2", "IARS2", "ICE2", "IDH2", "IGBP1", "IGF2BP2", "ILKAP", "ILVBL", "INCENP", "IPO11", "IPO5", "IPO7", "IPO9", "IQGAP2", "ITCH", "KDELR1", "KDM1B", "KEAP1", "KHDRBS3", "KHSRP", "KIAA0319L", "L2HGDH", "LBR", "LDAH", "LETMD1", "LIMA1", "LIN9", "LMAN2", "LNPK", "LPCAT2", "LUC7L", "M6PR", "MAN2A1", "MAPRE2", "MARCKS", "MARCKSL1", "MBNL1", "MCM3", "MCMBP", "ME2", "MED14", "MED16", "MED25", "MED27", "MGME1", "MGST1", "MIA2", "MIA3", "MINDY3", "MMS19", "MOGS", "MON2", "MORF4L1", "MOV10", "MPP1", "MPRIP", "MPV17L2", "MRE11", "MRPS7", "MRRF", "MSTO1", "MTBP", "MTFP1", "MTMR12", "MTMR2", "MTX1", "MYCBP", "MYO1D", "NAA15", "NAA40", "NANS", "NAP1L1", "NCAPD2", "NCDN", "NCLN", "NCOA5", "ND1", "NDUFA13", "NDUFA5", "NDUFB10", "NDUFB3", "NDUFB4", "NEDD4L", "NEFL", "NEFM", "NELFB", "NENF", "NLN", "NME6", "NNT", "NR2F2", "NRDC", "NSD2", "NSL1", "NSUN2", "NT5C2", "NUB1", "NUCB2", "NUDT9", "NUP35", "NXN", "OCLN", "OGDH", "OPA1", "OPA3", "ORC2", "ORC3", "OSBPL6", "OSBPL8", "OXA1L", "P3H1", "PABPN1", "PAK1IP1", "PAPSS1", "PCBD1", "PCF11", "PCYOX1", "PDCL3", "PELP1", "PEX11B", "PEX14", "PFDN1", "PHF10", "PHRF1", "PICALM", "PIK3R4", "PISD", "PLXNB2", "PMAIP1", "PMPCA", "PNPLA6", "POLD2", "POLR1C", "POLR2C", "POLR2D", "POLR2G", "POLR3A", "POLRMT", "PON2", "POP1", "PPP2R1B", "PPP4R1", "PPP4R2", "PRAF2", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB7", "PSME2", "PSMG1", "QTRT2", "RAB11B", "RAB11FIP1", "RAB12", "RAB18", "RAB1A", "RAB24", "RAB34", "RABAC1", "RAD51AP1", "RAVER1", "RBM10", "RBM3", "RBM6", "RCN1", "RCN2", "RECQL", "REPS1", "REXO4", "RFC3", "RFT1", "RHOA", "RHOT2", "RINT1", "RIOX1", "RNF139", "RPL36", "RPS10", "RPS14", "RPS15", "RPS19BP1", "RPS3", "RTN1", "RTN4", "SC5D", "SCO2", "SCPEP1", "SDF4", "SEC11A", "SEC22B", "SEC31A", "SEC61A1", "SEH1L", "SEL1L", "SENP3", "SEPT6", "SETDB1", "SF3B4", "SFXN4", "SGF29", "SH3GLB1", "SIGMAR1", "SKA3", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A33", "SLC25A4", "SLC25A42", "SLC35B2", "SLC44A1", "SLC7A1", "SLFN11", "SLIT2", "SMARCB1", "SPOP", "SRP19", "SRSF7", "SSR4", "STAG2", "STAU1", "STIM1", "STOML2", "STRN", "STX3", "STX6", "SUCLA2", "SUGT1", "SUMF2", "SUN1", "SYMPK", "SYNE2", "SYNGR2", "TAF15", "TAF9B", "TAMM41", "TAP1", "TAP2", "TBCB", "TBL1XR1", "TECR", "THEM6", "THOP1", "TIAL1", "TIMELESS", "TIMM10", "TMCO1", "TMEM165", "TMEM230", "TMPO", "TNPO1", "TOMM40", "TPBG", "TRIM27", "TRMU", "TSN", "TSPAN3", "TSPAN6", "TTC19", "TTC37", "TTC4", "TTLL12", "TTYH3", "TUBGCP3", "TWNK", "UBE2J1", "UBE2O", "UBE2S", "UBE3A", "UBIAD1", "UBQLN4", "UBR4", "UBTF", "UFSP2", "UGGT1", "UHRF1", "UNC119B", "UROD", "USP36", "UTRN", "VAMP7", "VKORC1L1", "VPS13A", "VPS25", "VPS45", "WDHD1", "WDR26", "WDR6", "WDR75", "WDR91", "XPNPEP3", "XRCC1", 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0.0482776184460361 0.0421632123974333 0.0088672129005513 7.337966463432867e-05 +Hydrogen ion transport 5 20 1.9899768856970348 0.046593481779857 6.152912621359223 19.560679611650485 0.8019462838912398 0.3170771992837126 2.890966221074556 1.405159537040464 1.2709247974732976 0.29451915785821 1.0 0.1389130578490434 0.2613412907301976 0.0065049624434193 0.0034490123110402 diff --git a/protein_atlas_biological_process/metrics.json b/protein_atlas_biological_process/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..36cde5b8b220c220f1eaacc998020c6435490344 --- /dev/null +++ b/protein_atlas_biological_process/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 172, + "title": "Average number of proteins per term", + "value": 29.78488372093023 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3e515299776049172086bfe30fa7fc23b6d45294 --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4339f8e7ff168566b8bf86b12ea9ad5fca2b19e7 --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,58 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Glyoxylate bypass 0.9250729808627922 3.1650819674929274 0.0015503926810416 0.2342308112018451 0.0126984543399599 2 P48735 1 +DNA excision 0.9577814086313308 2.7993056633091697 0.0051212633288022 0.5865094316861482 0.0352342917021594 3 Q9UQ84 1 +Peptide transport 0.8306843983133231 2.7413955565519363 0.0061178807344708 0.6519842435850316 0.0404721340895763 2 Q03518 1 +Transport 0.3154518963678619 2.4913649991946385 0.012725331662404 0.8895069504004361 0.066325971088894 497 Q99720,O43772,Q13505,P03886,Q13432,Q70HW3,Q5BJH7,Q8TBP6,P00846,Q8NC96,P41440,Q6P4A7,O14653,P62072,Q9UHQ4,P14373,Q16629,O95168,Q9P260,Q6N075,O60830,Q86VD7,A6NIH7,Q03518,Q8N2H4,O75964,Q9UP83,P50416,O95249,P56134,Q9P0J0,P61619,Q8IXU6,Q9NRW7,O43752,Q8WWI5,Q9Y487,Q15758,Q9Y3B3,O43676,O75381,Q9NUT2,Q96RL7,Q8TDW0,Q9UI26,Q9Y282,Q14746,Q13586,P24390,Q9C0H2,P83436,Q96CU9,O96000,Q9Y3E0,P46379,O75152,Q9HD20,Q96EE3,P51809,Q6NUQ1,O43823,O43808,Q9BSK2,O60831,Q6IQ22,Q9C0C9,Q86YS7,Q16718,P30825,Q9UM00,Q9BUR5,Q96AA3,P08574,O75396,Q9BQT8,Q9BZF3,Q96P70,Q96NB2,Q9Y5P4,Q99653,O96008,Q9Y5K8,Q5JRA6,Q96ES6,Q9Y619,Q9NP72,Q8NE01,O15126,P31751,O95782,Q969Q5,O43169,O00400,Q93050,Q12907,O95182,O94832,P98194,Q8TB61,Q13277,O00471,Q6WKZ4,Q8NFH5 103 +Protein transport 0.326850149616487 2.29119657375359 0.0219520470450933 0.9780241575999606 0.0918005010300751 242 Q8NFH4,Q567U6,P61619,Q9HD20,Q7Z3U7,P52292,Q13505,P49257,Q13432,Q03519,Q9NRW7,O60749,Q5BJH7,O43752,O00410,O95070,O43823,O60831,Q6IQ22,Q99595,Q8NC96,Q9BRG1,Q86YS7,Q9NP72,Q9Y3B3,Q92538,O75381,O15126,Q5JRA6,Q96EE3,O14653,A0AVF1,Q96RL7,P62072,P51809,O95782,Q969Q5,Q9UHQ4,Q6NUQ1,O75396,Q9UI26,P60520,Q15907,Q12907,O94832,Q14746,O60830,P24390,O00471,Q96P70,Q6WKZ4,Q8NFH5,Q92973,O95373,O43731,Q03518,A6NIH7,P83436,Q8N2H4,Q9UP83,O95249,Q96CW1,P62820,Q9Y3E0,P63010,Q99653,O94979,O96008 68 +Hypusine biosynthesis 0.6769380473564695 2.0033757558449494 0.0451369717116636 0.9996452965402456 0.1581535653706367 2 Q9BU89 1 +Hydrogen ion transport 0.560780582521298 1.9899768856970348 0.046593481779857 0.999727205201722 0.1581535653706367 20 Q9Y5K8,O75964,Q9Y487,P00846,P56134 5 +DNA synthesis 0.713845833080935 1.7536776051016627 0.0794857650047111 0.999999349499656 0.2205088964646826 3 Q5TKA1 1 +ATP synthesis 0.7487564994988416 1.7341769536032223 0.082886690800588 0.9999996558440268 0.2262938225031928 8 P00846,O75964 2 +Steroid biosynthesis 0.4828101399501932 1.6223241916799491 0.1047339514790721 0.9999999945579344 0.2610759370202958 24 Q9H3P7,Q14739,Q15392,P56937,Q9UHQ9,Q53GQ0,Q9BX68,O75845 8 +Meiosis 0.5660167428823457 1.5784615048399138 0.1144596250714817 0.9999999991685444 0.2735857245079435 14 Q9UQ84,P24941,Q96B01,P49959,Q8N3U4,O94901,Q92878 7 +Vision 0.7483236609937602 1.5577349123757622 0.1192961008028823 0.99999999967585 0.2735857245079435 6 Q13432,Q9H6K4 2 +Sensory transduction 0.7483236609937602 1.5577349123757622 0.1192961008028823 0.99999999967585 0.2735857245079435 6 Q13432,Q9H6K4 2 +Lipid degradation 0.5562736456453745 1.5218066250053497 0.1280575410010491 0.999999999941936 0.2898144348971112 14 Q9H6V9 1 +Neurogenesis 0.3950770876874985 1.3537094449663205 0.1758290936505899 0.9999999999999964 0.3688122452183106 41 Q8WUJ1,Q96N67,Q9NQC3,Q8WUB8,Q13555,O94813,Q9Y6E2,Q12824,Q9P265 9 +Cilium biogenesis/degradation 0.5064268535061907 1.3086696831251718 0.1906462654098053 1.0 0.3903709244105538 15 Q96J42,A6NIH7 2 +Sterol biosynthesis 0.4740970033342487 1.2818264093058624 0.1999035477454422 1.0 0.4045107083790126 17 Q14739,Q15392,Q9UHQ9 3 +Antiviral defense 0.4316303530223935 1.2428693551069234 0.2139159799566596 1.0 0.4229143511786835 24 Q8IZ81,Q9NUD5,Q13217,Q96J02,O14802,Q7Z7L1 6 +Biological rhythms 0.3707950222825692 1.1481336776868756 0.2509133832296768 1.0 0.4815058440142786 42 Q9UNS1,Q03164,O75376,P43490,Q13547,Q9Y2K7,Q05086 7 +GMP biosynthesis 0.5098929614012213 1.1456240726947844 0.2519507323330527 1.0 0.4815058440142786 2 P49915 1 +Endocytosis 0.4136360409766503 1.131003627334965 0.2580535647076925 1.0 0.4825917472088314 25 Q13432 1 +Nucleotide metabolism 0.614458496837387 1.1308209283294566 0.2581304694372819 1.0 0.4825917472088314 8 P49902,O75414,Q969T7 3 +DNA replication 0.3513453504938916 1.118683515465683 0.263275180189602 1.0 0.486917537554963 49 P40938,P31350,Q96RR1,Q14181,P49736,Q9UFC0,P49005,P25205,Q9BRX5,P33993,Q9BTE3,Q9Y5N6,Q9BRT9,P56282,Q13416,P49321,Q96S55,Q9UBD5 18 +Lipid transport 0.4174236248352985 1.0100321491012465 0.3124798875875876 1.0 0.5321439669808422 20 Q99720,Q9BZF3,Q9BUR5,Q9P260 4 +Differentiation 0.3237625308619587 1.003182884656464 0.3157726293920704 1.0 0.5324793358376089 74 P85037,O96005,Q07820,O94813,O94901,Q14141,Q96SI9,Q6DKJ4,P78362,Q9GZM5,Q96A49,Q6P6C2,Q96N67,Q99426,Q08J23,Q9Y6E2,Q96PU5,P51114,Q9BXJ9,P54652,Q13555,P46379,Q9BUP3 23 +Respiratory chain 0.3688016757172174 0.9744270196025088 0.3298445590851879 1.0 0.5465453205698169 34 O43676,P03886,O95168,Q96CU9,O96000,Q16718,Q9P0J0 7 +Cholesterol biosynthesis 0.4391729539712134 0.9088171999931898 0.3634466258969375 1.0 0.5857933937479105 15 Q15392 1 +Ubl conjugation pathway 0.2979534785913748 0.9069788470937704 0.364417983319921 1.0 0.5857933937479105 115 Q96T88,Q96HY6,Q14527,Q9C0C9,Q9UJX3,Q9H1A4,Q9BZK7,Q9Y2K7,P14373,Q96K76,Q05086,Q9NUQ7,O75155,Q96J02,Q9H8M7,Q14145,Q16763,Q96PU5,Q13616,O43791,Q96DY7,Q5T4S7 22 +ER-Golgi transport 0.3289320166241591 0.8776374022638943 0.3801405249922722 1.0 0.5971493695344445 48 O60763,Q9Y282,Q5JRA6,O94979,Q6NUQ1,P49257,O95249,Q9Y678,O95070,P62820,Q9UHQ4,O43264,P24390,P49755,O75396,O95487,Q8N6T3,O43731 18 +Biomineralization 0.443399286409332 0.8066848835131497 0.4198480554025554 1.0 0.6390607568959251 2 Q9UBB9 1 +Myogenesis 0.5623507147775608 0.7836615244985716 0.4332387445242012 1.0 0.6479744700709792 5 P85037 1 +Ion transport 0.3018471724096309 0.7184506830623993 0.4724794457705266 1.0 0.6792500879099787 60 Q9Y5K8,O75964,Q9NUT2,O96008,Q9UM00,Q13586,Q6N075,Q9Y487,Q8TDW0,P00846,Q9C0H2,P56134,Q93050,Q8NE01 14 +Angiogenesis 0.4745437349549223 0.6862462037911042 0.4925578663092418 1.0 0.7001649008693355 10 Q9H2J4,P17252,Q9BXJ9,Q9BUP3 4 +Methionine biosynthesis 0.4420502011783915 0.5414708223991129 0.58818310342364 1.0 0.8029166173719531 3 Q99707 1 +Apoptosis 0.2579885662449622 0.4609011876664116 0.6448694996376343 1.0 0.8722121029326202 118 P46379,Q9H2J4,Q13794,O75414,Q03164,Q9UDX5,O60566,Q9Y371,Q96KA5,Q96J02,Q9UHQ4,Q9Y2J2,Q9H8M7,O14681,Q96F07,O95831,P09601,Q9P0J0 18 +Amino-acid transport 0.4624990907542426 0.4550294157064274 0.6490880766010196 1.0 0.8722121029326202 7 P30825,Q6P4A7,Q15758 3 +Phagocytosis 0.4136988702283227 0.4345468849200667 0.6638913560690085 1.0 0.885188474758678 3 P50570 1 +Chromosome partition 0.318594646670663 0.4212339498606205 0.6735842558243823 1.0 0.8864312422707421 21 Q8NFH4,Q8NFH3,Q96EE3,Q96T76,Q96IY1,O43684,Q9NQS7,O60216,Q8N3U4 9 +Glycogen biosynthesis 0.4615193217879811 0.4191168021201315 0.6751307717294606 1.0 0.8864312422707421 4 P35573,P31751 2 +Phospholipid metabolism 0.3202270827565364 0.4015203435884339 0.6880370633427044 1.0 0.8935120400324752 19 Q96BW9,P48651,Q9NPH0,Q9UG56,Q9BVG9,Q7L5N7,Q9HCL2 7 +Calcium transport 0.4040842381834941 0.397615843791012 0.6909133797925535 1.0 0.8935120400324752 10 Q9UM00,Q13586 2 +Autophagy 0.292366462459782 0.3786749930301722 0.7049292254726673 1.0 0.9048345282186476 29 Q969Q5,Q9Y371,P62820,Q6IQ22,O14681,Q9NRR5 6 +Tricarboxylic acid cycle 0.3109028798278752 0.370787027752921 0.71079616409951 1.0 0.9056069646304868 20 Q9P2R7,P48735 2 +Lipid biosynthesis 0.2598962578596211 0.358617600167586 0.7198811784332013 1.0 0.908727036560107 63 Q9H3P7,Q96BW9,Q9NZ01,Q15392,Q96G23,P48449,Q13131,P56937,Q15185,P48651,P38398,Q53GQ0,Q9HCL2,O75845,Q9UG56,Q9BX68,Q99943,Q14739,P54619,Q9UHQ9,P14324,Q9BVG9,Q7L5N7 23 +Adaptive immunity 0.338761888796073 0.3527907172660797 0.7242453434458733 1.0 0.908727036560107 14 P04439,Q9NZ08,Q03519,Q13740,Q03518 5 +tRNA processing 0.2862321573583036 0.3256800341975957 0.7446664517500297 1.0 0.908727036560107 27 Q99575,O75648,Q7Z2T5,P62312,Q5VV42,Q9H974 6 +Immunity 0.2525401098874156 0.3180724631721699 0.750429970976644 1.0 0.9089715141407236 68 P04439,Q9NZ08,O95801,Q14166,O43823,Q03519,Q9NUD5,Q96J02,P41240,P17812,Q13740,Q9UQ84,O14802,Q9UN86,Q7Z7L1,P46379,Q96S55,Q03518 18 +Pyrimidine biosynthesis 0.3973307151943686 0.2400273194835251 0.8103090777023807 1.0 0.9534127108228404 5 P17812 1 +DNA condensation 0.39178613584336 0.2271312338164821 0.8203216975819989 1.0 0.9534127108228404 6 Q9NTJ3,Q15021 2 +Exocytosis 0.2745544297270894 0.1813400988174743 0.8561006334381589 1.0 0.9534127108228404 16 Q9BRK5,Q5JRA6,P51809 3 +Nucleotide biosynthesis 0.3660806856776953 0.1739590804383061 0.8618976209118085 1.0 0.9534127108228404 4 Q14558 1 +mRNA capping 0.3641659394697895 0.1703649228797407 0.8647231563276925 1.0 0.9534127108228404 4 Q8N1G2,Q53F19 2 +Cell shape 0.3415584415584533 0.1316896883068964 0.8952297420201303 1.0 0.9807612460347924 5 Q96AC1,P35579,P35580,Q7L576 4 +Mitosis 0.1943882265285474 0.0904527307659896 0.9279274552933324 1.0 0.9996029568681604 111 Q8NFH4,Q9UJX2,Q96EE3,Q15555,Q14203,Q03188,Q9NTJ3,O75935,Q9ULW0,Q9BPX3,Q9UJX3,Q9UNS1,Q9H1A4,P23396,Q96IY1,Q9BTE3,P11171,P14635,O60566,O43684,Q9NQS7,Q9H6D7,Q9UJX4,Q15691,P48729,Q8N3U4,Q08J23,Q15021,Q8IY18,Q8NFH3,Q9Y5K6,Q8IX90,Q9H6H4,P52732,Q9Y6G9,Q2NKX8,Q68CZ6,Q53HL2,O43264,P50748,Q96FF9,P24941 42 +One-carbon metabolism 0.2762464479630653 0.0895820813978932 0.928619324121286 1.0 0.9996029568681604 10 P00374 1 +Cell division 0.1736272317602381 0.0880169356357165 0.929863215691312 1.0 0.9996029568681604 144 Q8NFH4,Q9UJX2,Q96EE3,Q15555,Q14203,Q03188,Q9NTJ3,O75935,Q9ULW0,Q00535,Q9BPX3,Q14141,Q9UJX3,Q9UNS1,Q9H1A4,P23396,Q96IY1,P36405,Q9BTE3,P61586,P11802,P11171,P14635,P08754,O60566,O43684,Q9NQS7,Q9H6D7,Q9UJX4,Q15691,Q16763,P48729,Q8N3U4,Q08J23,Q15021,Q8IY18,Q8NFH3,Q9Y5K6,Q6DKK2,Q8IX90,Q9H6H4,P52732,Q9Y6G9,Q2NKX8,Q68CZ6,Q53HL2,O43264,P50748,Q96FF9,P24941 50 +mRNA transport 0.1558167873026868 0.0387573438246201 0.96908385395881 1.0 1.0 66 Q8NFH4,Q96EE3,Q7KZ85,Q96J01,Q5JVF3,Q9UN86,P63241,Q92945,Q9Y5S9,Q16629,Q96FV9,Q8WUM0,Q9BY77,Q9Y6M1,Q8NFH5,Q8NFH3,Q53F19,O75694,O75152,Q12769 20 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..73baf2ec79f2a01dcd925bdeb14b66534d247279 --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Anion exchange", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Copper transport", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "Digestion", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Ion transport", "Iron storage", "Isoprene biosynthesis", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Menaquinone biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sexual differentiation", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT2", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALG13", "ALKBH5", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEX1", "API5", "APOO", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARG2", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL8A", "ARL8B", "ARMC10", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATG3", "ATIC", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATRIP", "ATRX", "AUP1", "AURKA", "AURKB", "BABAM2", "BAG3", "BAG6", "BAHD1", "BAK1", "BANF1", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BICD2", "BIRC6", "BLM", "BMI1", "BMS1", "BNIP1", "BOP1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C2CD5", "CAAP1", "CACYBP", "CAD", "CAMK2G", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CARS2", "CBR4", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC59", "CCDC86", "CCDC93", "CCNB1", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC34", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CEBPZ", "CELF1", "CELF2", "CENPC", "CENPU", "CENPV", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CGGBP1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHST14", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLIC1", "CLPTM1", "CLPTM1L", "CLSPN", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "COG2", "COG5", "COG6", "COG7", "COL4A3BP", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS6", "COPZ1", "COQ8A", "COQ9", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCPS", "DCTN1", "DCTN3", "DCXR", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DECR1", "DECR2", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX15", "DHX16", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLST", "DMAP1", "DNAAF5", "DNAJB1", "DNAJB12", "DNAJC13", "DNAJC19", "DNAJC3", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPYSL2", "DSC1", "DSC3", "DSG2", "DST", "DTYMK", "DUS2", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECH1", "ECHS1", "ECI1", "ECSIT", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFL1", "EFTUD2", "EHD1", "EHHADH", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC4", "EMG1", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESCO2", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAM162A", "FAM208A", "FANCD2", "FANCI", "FAR1", "FAR2", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXK1", "FOXRED1", "FRYL", "FTL", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCFC2", "GCLC", "GCN1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GHITM", "GID8", "GINS3", "GINS4", "GLRX", "GM2A", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPI", "GPR89B", "GRB2", "GRSF1", "GRWD1", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HELLS", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGXB4", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD11", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILVBL", "IMP4", "IMPDH2", "INA", "INCENP", "ING5", "INTS13", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRF2BP1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDLR", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LMAN1", "LMAN2", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPPRC", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L3", "LYAR", "LYN", "LYPLA1", "M6PR", "MACF1", "MAEA", "MAGT1", "MANF", "MAPK1", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MESD", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGEA5", "MGME1", "MGST2", "MIA3", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MKRN2", "MLEC", "MMS19", "MOCS1", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL41", "MRPL58", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MYBBP1A", "MYCBP", "MYDGF", "MYH10", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCEH1", "NCKAP1", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NME1", "NME6", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP10", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPM1", "NR2F2", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUBP1", "NUCKS1", "NUDC", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OGDH", "OGT", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "PA2G4", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCF11", "PCID2", "PCK2", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDK1", "PDK3", "PDS5A", "PDS5B", "PDZD8", "PECR", "PEDS1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGP", "PGS1", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHGDH", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIN1", "PISD", "PITPNB", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLIN3", "PLK1", "PLRG1", "PMAIP1", "PMF1", "PMVK", "PNN", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "POP1", "PPAT", "PPID", "PPIE", "PPIF", "PPIH", "PPIL3", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKCA", "PRKCB", "PRKDC", "PRKRA", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK7", "PTPMT1", "PTRH2", "PUF60", "PURA", "PUS1", "PWP1", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB35", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM14", "RBM15", "RBM17", "RBM22", "RBM23", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCOR1", "REEP3", "REEP4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN3", "RMND1", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPS1", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP14", "RPP30", "RPP38", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RPUSD3", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSF1", "RSL24D1", "RSRC1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SAR1A", 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"results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..292442d7b55d195707b90e568e17cf2dd0eabbba --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,32 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Leber hereditary optic neuropathy 0.9925397340252996 3.455078384050626 0.0005501328604009 0.0602882681616635 0.0110344823646763 2 P03886 1 +Corneal dystrophy 0.9127473240350282 3.1109739397287273 0.0018647139500442 0.1901525483574368 0.0175593896962503 2 Q9Y5Z9 1 +Dwarfism 0.4343119042954951 1.969330350490502 0.0489151681078821 0.9965423910614324 0.1454582630576494 49 Q14739,Q99575,Q96DX4,Q32P28,Q13868,Q96HY6,Q8IY17,O95831,Q9NR45,O15228 10 +Congenital disorder of glycosylation 0.489943052061163 1.7036414757132088 0.0884480879030578 0.9999714701871796 0.1998926786609106 25 Q14746,P51571,Q9UP83,Q96AA3,P34949,Q9NP73,Q9HC07,O60762,Q9BT22,P83436 10 +Epilepsy 0.3874825111795972 1.6841491756194409 0.0921528426928119 0.999981993081562 0.2041817887115246 63 P49419,Q9C0E8,Q96RL7,P03886,O14653,Q96F07,Q8NC96 7 +Fanconi anemia 0.7576864197542417 1.573608867707402 0.1155779018892504 0.9999990612863386 0.233219694883666 4 Q9BXW9,Q9NVI1 2 +Hermansky-Pudlak syndrome 0.574764839442095 1.4825708146196437 0.1381884760968723 0.9999999496975004 0.2559884885073209 2 O00203 1 +Albinism 0.574764839442095 1.4825708146196437 0.1381884760968723 0.9999999496975004 0.2559884885073209 2 O00203 1 +Ciliopathy 0.6820532039744805 1.4351922232837744 0.1512323290623978 0.9999999910228662 0.2712579870484278 8 P36405,Q9NVR5,Q96J42,P49959 4 +Retinitis pigmentosa 0.5149453098385077 1.3599883908165742 0.1738335976443992 0.9999999995747632 0.2931820378181658 15 Q8IY17 1 +FDA approved drug targets 0.3328591953833425 1.3317910628192156 0.1829288555640995 0.9999999998782788 0.3039847158638712 111 Q99720,P03886,Q13547,Q15758,Q02218,P48735,P00374,P38435,Q8N0U8,P49721,P11802,P98194,P28074,Q13423,P09525,Q14145,P42345,P20645,O75874,P50416,P20618 21 +Autism 0.6677840963766974 1.2121380068428096 0.2254595571282398 0.9999999999997102 0.3489990404861794 5 Q8NDZ4,P06730,Q9HCK8 3 +Diabetes mellitus 0.5968043444649335 1.1542584369124025 0.2483942310202218 0.9999999999999905 0.3693230013853298 9 P03886,Q13217,P31751 3 +Proto-oncogene 0.3651770028238572 1.13824945861693 0.2550163317552727 0.9999999999999964 0.3713087588595213 44 P26196,P31751,Q92804,Q03164,O94979,Q92733,P35637,Q13492,P14373,Q8WY22,P55196,O96028,P61586,Q6P1Q0 14 +Osteogenesis imperfecta 0.5791747337173855 0.9738350269806632 0.3301384583855959 1.0 0.4597770799328344 8 Q32P28 1 +Primary mitochondrial disease 0.309507876206435 0.924671322434374 0.3551369009172263 1.0 0.4721231741605479 104 O43676,Q9P2R7,Q6P4A7,P13073,Q9NPL8,Q96RR1,P03886,O43819,Q70HW3,Q96CU9,Q9BQP7,O95363,Q8NFF5,P08574,P00846,O95831,Q9P0J0,Q96IX5 18 +Progressive external ophthalmoplegia 0.5600858409728444 0.7747932273600483 0.4384618518946128 1.0 0.563024878001037 5 Q9BQP7,P12235,Q96RR1 3 +Ectodermal dysplasia 0.533137595334623 0.6711493721315532 0.5021253772276377 1.0 0.6304463069635896 5 Q9H1A4 1 +Peroxisome biogenesis disorder 0.515416797337129 0.6032230515487358 0.546360314665215 1.0 0.6710729951866227 4 O75381 1 +Neurodegeneration 0.2578280661361946 0.531993473597194 0.5947305156953235 1.0 0.7087796202867237 134 Q99720,Q96RR1,P03886,Q8WWI5,Q10713,Q13614,Q8IY17,P17480,P18887,O14653,Q96RL7,O00400,Q9NRR5,O15269,Q9BRK0,Q9NQT5,O95831,Q96B26,Q71SY5,P07196,O95363,Q96D71,Q99653,O60313 24 +Hypotrichosis 0.4837673577734355 0.5303393451624628 0.5958766719224668 1.0 0.7087796202867237 7 Q12824 1 +Neuropathy 0.2851125151563156 0.461199687352271 0.6446553459825248 1.0 0.7509902484126321 45 Q96RR1,P07196,Q13614,P00846,O95831,Q9NSE4,O15269 7 +Leigh syndrome 0.4149644553331154 0.4380532947476254 0.6613476502000184 1.0 0.7570510731443075 10 P00846 1 +Microphthalmia 0.4659882139899138 0.4354206351777699 0.6632571348786411 1.0 0.7570510731443075 6 P53701 1 +Deafness 0.2692232802670854 0.3626252765832457 0.7168848257397902 1.0 0.8040876240456559 46 Q96RR1,O75648,Q9NWM8,Q13868,O00400,O95831,O60313,Q9NSE4 8 +Diamond-Blackfan anemia 0.3328990228013037 0.3601997149424145 0.7186977878638163 1.0 0.8040876240456559 15 P61254,P18077,P62273,P62847,P62913,P62081,P39019,P46777,P08708,Q07020,P62244,P46783,P42766,P61313 14 +Autism spectrum disorder 0.2983058668340242 0.2319680126569268 0.8165628584076092 1.0 0.8787771714291414 15 Q05639,Q8NDZ4,Q12955 3 +Disease variant 0.2042842231626428 0.2090448822944352 0.8344132015397951 1.0 0.8895159601320457 784 Q99720,P11310,Q15392,P49419,O43772,P03886,Q13432,Q70HW3,Q8IY17,P00846,P48735,Q99575,O14653,Q9BZK7,Q9HC07,Q05086,Q9BRK0,Q9P2R7,Q9NQT5,Q13423,Q96F07,O95831,Q9NQH7,Q86VD7,Q8TD30,Q96B26,Q9C0E8,P50416,O43819,P34949,P28070,Q9P0J0,Q9Y5Z9,Q12824,Q9NSE4,P13073,Q16625,P61619,Q96RR1,Q9NRW7,Q13614,Q9NR45,Q96J42,O43676,Q96AY3,Q96RL7,P38435,O14681,P57678,Q86U42,Q96DX4,Q14746,Q13586,Q9BQP7,Q9BUK6,Q8N3U4,O15228,Q14739,Q9UEY8,P07196,Q96CU9,O95363,Q9H6K4,Q6NUQ1,Q9NR56,P06132,Q9BXW9,Q9H9P8,P00374,Q9UM00,Q96AA3,Q13868,P08574,Q8NFF5,P61586,P11802,O75845,O15269,Q9NUQ7,Q9BQT8,Q8WXH0,Q13724,O75648 83 +Elliptocytosis 0.2731106065520652 0.1494161978551275 0.8812252311601814 1.0 0.9093091009710744 2 P11171 1 +Primary microcephaly 0.3497675319355994 0.1444208526504807 0.8851681513877714 1.0 0.9093091009710744 6 Q15021 1 +Mental retardation 0.1939836535339555 0.104155133004996 0.9170462389212284 1.0 0.9335695945774668 165 Q9NZ01,Q9H7D7,P48449,P26640,Q10713,Q8IY17,Q9NR45,P78318,P17480,Q9UM00,Q12955,Q9BZK7,P51812,Q9H9B1,Q15907,Q68CP9,Q96DX4,Q05639,Q9UG56,O95831,Q08J23,Q8TD30,Q71SY5,P42345,Q9C0E8,O43791,Q13555,Q9Y5P4,Q9BXJ9,Q12824 30 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..73a920b896ca218b372ed70effebb609e83fc7fe --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital dyserythropoietic anemia", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Corneal dystrophy", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AARS", "AARS2", "ABAT", "ABCB1", "ABCB7", "ABCC1", "ABCD4", "ABHD12", "ABI1", "ACAA1", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADAR", "ADD3", "ADK", "ADNP", "ADSL", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AKAP12", "AKR1B1", "AKT2", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANO10", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA7", "AP1B1", "AP1S2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APEX1", "APRT", "ARCN1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL2", "ARL3", "ARL6IP1", "ASAH1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATIC", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP7A", "ATP7B", "ATRX", "ATXN10", "AURKA", "AURKB", "B4GAT1", "BAG3", "BANF1", "BARD1", "BAX", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCKDHA", "BCKDHB", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BMI1", "BMS1", "BPTF", "BRCA1", "BRD3", "BRD4", "BRI3BP", "BUB1B", "BUD23", "C19orf70", "C1QBP", "C3orf58", "CAD", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBX2", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC6", "CCNB1", "CCT5", "CDC16", "CDC27", "CDC34", "CDC37", "CDC42", "CDC73", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDKAL1", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHEK1", "CHP1", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLPB", "CLPP", "CLPX", 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sha256:a99cf61dd3053131f14ca5e200a1ab73dd9f4c2c510ca7b2f9052de847866441 +size 145003 diff --git a/protein_atlas_molecular_function/consensus.joblib b/protein_atlas_molecular_function/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..89647ab1261c26f94dfd0e5f50b4641d2348cdcc --- /dev/null +++ b/protein_atlas_molecular_function/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b5a25558d4a3a49cbc95cce0900f637abb9bb4eb3b17a5e832eb92566b2c06cc +size 78763 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b7cab7fc04b99f5fe4d07b9668a96de42c3e3e47 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Oxidoreductase 31 174 3.639618051765401 0.0002730427401487 36.64563106796116 165.7621359223301 0.5091071251362119 0.5527126631147542 14.160338956360992 12.210799107974529 1.1772957028589783 0.3900527505954884 0.0003759754982657 0.00023880690681 3.249811881079459e-05 4.742354302136421e-05 0.0001055153692229 +Metalloprotease 6 25 2.2682662773842424 0.0233129820010915 8.160194174757281 26.429611650485437 1.390302281711237 0.2661274848815638 3.192614043118206 1.543038499308978 1.1108461579919544 0.309446154241223 1.0 1.0 0.1088269092294783 0.0528261722730647 0.0223659228002449 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..782bfd22c4023e6a47fa35a2043f7fc5b87210ba --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 97, + "title": "Average number of proteins per term", + "value": 37.329896907216494 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9f443b3b70fc4ab58b497b6450ad2b87bba9d6b5 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..166be21a17cbf218b6f56a99d64a150309982d2e --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,26 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Oxidoreductase 0.4329337789985871 3.6396180517654018 0.0002730427401487 0.0261410122334777 0.0037835922563465 174 P13073,P11310,Q8NB78,Q15392,P49419,Q8N4Q0,P56937,Q02218,P30837,Q9H9P8,P48735,P00374,Q32P28,Q8TED1,Q8N0U8,Q9H6W3,P13674,Q9Y2K7,Q53GQ0,P09601,P78417,P30519,O75845,Q6P6C2,O15254,O95831,P23368,Q14739,O75874,Q96CU9,Q9UHQ9 31 +Metalloprotease 0.5665378518686457 2.2682662773842424 0.0233129820010915 0.8985445757104648 0.113067962705294 25 Q9NZ08,P55786,O43847,P52888,Q9NQH7,Q7Z2K6 6 +Dioxygenase 0.6139298812781959 1.9513004104702616 0.0510213202797804 0.9937787711489268 0.1979627226855482 15 Q6P6C2,Q9H6W3,Q9Y2K7,Q32P28 4 +tRNA-binding 0.5644620698297553 1.8633284270393176 0.0624160730144183 0.9980725420981488 0.2087710028413302 17 O43592,O75648,Q7Z2T5,P56192,Q5JTZ9,Q7Z7L1,Q08J23,Q92552,Q9H9T3,Q9HAV4 10 +Guanine-nucleotide releasing factor 0.6250749427774226 1.771552235957733 0.0764689143680761 0.9995545517439716 0.2472494897901128 13 P80303,A4D1U4,Q9Y4F1 3 +Chromatin regulator 0.3724929985084995 1.7390476481906674 0.0820263820562923 0.9997519556153892 0.2478161347548345 101 Q8NB78,Q96T88,Q03164,O75376,Q86X55,Q96KQ7,Q15047,Q14527,Q13547,Q9H7B4,Q9BZK7,Q96ES7,Q9H6W3,Q9Y2K7,Q9H9B1,Q15059,Q96JM7,Q9UBU8,P46379,Q12824 20 +Threonine protease 0.709012331026452 1.731864572244281 0.0832976778792251 0.999783155628998 0.2478161347548345 3 P28074 1 +Developmental protein 0.3724487943368202 1.590787401284555 0.1116574292407923 0.9999897125901248 0.2895611747637425 72 O15031,Q8NB78,Q9UNS1,Q9Y4F1,Q9C0E8,P85037,Q96SI9,P31277,Q92520,Q96N67,O96005,Q13555,O94813,Q9BXJ9,Q9NP72,Q9Y6E2 16 +Aminopeptidase 0.6145231383329555 1.356846168411217 0.1748300943595775 0.9999999919701408 0.4239629788219755 10 Q9NQH7,P55786 2 +Rotamase 0.4609442928494403 1.306963963729395 0.191224950558708 0.9999999988537186 0.439180311334631 20 O95302,P26885,Q9NWM8 3 +Calmodulin-binding 0.4253090708725873 1.299308067669858 0.1938382267827507 0.9999999991625604 0.439180311334631 28 P49006,Q9UEY8,O94832,P29966,Q13555,P35611,Q13576,Q5T4S7 8 +Translocase 0.4147769103097702 1.1882732411691486 0.2347257764976218 0.9999999999946264 0.4747033972963935 27 Q13423,P03886,Q9HD20,Q03518 4 +Exonuclease 0.4546614706544066 1.187818881332523 0.2349047739198648 0.9999999999947472 0.4747033972963935 18 Q9BQP7,Q9BQ61,Q9UQ84,Q9GZR2 4 +Methyltransferase 0.3641712913484057 1.1287018822641726 0.25902361500719 0.9999999999997652 0.5026671423507184 44 Q9H7B4,Q03164,Q86X55,Q15047,O60725 5 +Decarboxylase 0.6040273714687765 0.9501379749367894 0.3420421496471872 1.0 0.6039116335437539 5 P06132 1 +Heparin-binding 0.603842058427404 0.9493864052092976 0.3424241221124378 1.0 0.6039116335437539 5 O94813 1 +Protease 0.3137225002998295 0.888282298823246 0.3743889188839191 1.0 0.6484950916382171 74 Q9NP73,P52888,Q9BYT8,P42785,P67812,Q99436,Q7Z2K6,Q96K76,Q9NZ08,Q9NUQ7,P28074,P55786,Q9H8M7,Q9NQH7,Q9H4L4,P61009,O43847,Q9P275,Q9HB40 19 +Nucleotidyltransferase 0.4081748259879199 0.86324572335176 0.3880023792172957 1.0 0.6602847505978542 17 Q9NRG0,O00411,O14802,O43252,Q8NFF5 5 +Thiol protease 0.3609856716507224 0.6862392774626979 0.4925622332991306 1.0 0.7706215585486399 22 P45974,Q9NUQ7,Q9H4L4,Q9NP73,Q86UV5,Q9H8M7,Q9P275,Q96K76 8 +Initiation factor 0.3315808606356476 0.6296481738106812 0.5289247976365301 1.0 0.786324198532067 30 O15372,Q9Y262,P60228,Q7L2H7,P55010,O15371,O75822,P23588,P06730,P05198 10 +Serine/threonine-protein kinase 0.2883883495494825 0.4738153169795557 0.6356316110123288 1.0 0.8563370315027207 44 P42345,P31751,O60566,P78362,Q13555,P51812,P24941,O14976,Q96KB5,Q99570,P50750,O14757,P11802,Q13418 14 +Elongation factor 0.2710808463450286 0.0940075996829931 0.925103119800024 1.0 1.0 11 Q96RP9,P63241,Q05639 3 +Glycosyltransferase 0.2023779445215364 0.0881648840582144 0.9297456270599568 1.0 1.0 36 Q13126,P26572,Q9NP73,P43490,O60762,Q9NYU2,Q9BT22 7 +Actin-binding 0.1889686678220785 0.0597939039746997 0.9523197808148764 1.0 1.0 68 P49006,Q6WCQ1,P46939,O94832,Q9UEY8,P50402,Q9UHB6,P29966,P60981,Q14315,Q8WXH0,Q9Y613,Q9Y2J2,P35611,Q7L576,O15145 16 +Allosteric enzyme 0.1890701159067559 0.0568941656801296 0.9546295018995152 1.0 1.0 18 P23368,P49902 2 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e6255cc73f56418fb8a5e0c7d32fc2ca2b8fa3e3 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA replication inhibitor", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgG-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCC1", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "ANLN", "ANO6", "ANP32B", "ANXA1", "ANXA2", "APBB1", "APEH", "APEX1", "APLP2", "APRT", "AQR", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL8B", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7A", "ATP7B", "ATRX", "AURKA", "AURKB", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BANF1", "BAP18", "BARD1", "BAZ1B", "BCAT2", "BCKDHA", "BCKDHB", "BCLAF1", "BCOR", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "CAD", "CALR", "CAMK2G", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX2", "CBX3", "CBX8", "CCAR1", "CCAR2", "CCDC47", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC34", "CDC37", "CDC42", "CDC5L", "CDCA7L", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPU", "CEPT1", "CERS1", "CERS2", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT9", "CNP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPS5", "COQ8A", "CORO1C", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRYZ", "CS", "CSDE1", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CUL5", "CXADR", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCPS", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLK", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EHHADH", "EHMT1", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPRS", "ERAL1", "ERAP1", "ERCC3", "ERCC6L", "ERMP1", "ERO1A", "ERO1B", "ERP44", "ESCO2", "ESD", "ETFDH", "EXD2", "EXO1", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "F11R", "FADS2", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLYWCH1", "FMR1", "FN3KRP", "FOXK1", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDE1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GGCT", "GGCX", "GGH", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPI", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPAD1", "IMPDH2", "INA", "ING5", "INTS11", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "KARS", "KAT7", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIAA1147", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KRR1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPAP1", "LRPPRC", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L3", "LYAR", "LYN", "LYPLA1", "M6PR", "MACF1", "MAEA", "MAGED2", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAPK1", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MATR3", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFN1", "MFN2", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOCS1", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MYBBP1A", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCAM1", "NCBP2", "NCBP3", "NCEH1", "NCL", "NCOA5", "NCOR1", "ND1", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NEPRO", "NES", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NKRF", "NKTR", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUCB1", "NUCB2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NUSAP1", "NXF1", "NXN", "OAT", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC6", "OTUB1", "OXCT1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PEBP1", "PECR", "PEDS1", "PELO", "PELP1", "PEPD", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB2", "PHC2", "PHF2", "PHF5A", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PIAS1", "PIGG", "PIGK", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP5C", "PPP6C", "PPT1", "PPT2", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKCA", "PRKCB", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRSS3", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "RAB10", "RAB11B", "RAB18", "RAB1A", "RAB1B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAI1", "RALA", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC3", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOX1", "RIPK1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNMT", "RNPC3", "RNPEP", "RNPS1", "ROMO1", "RP2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP14", "RPP30", "RPP38", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RREB1", "RRM1", "RRM2", "RRP1B", "RRP7A", "RRP8", "RRP9", "RSBN1", "RSBN1L", "RSF1", "RTCB", "RTF1", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARNP", "SARS", "SARS2", "SART3", "SC5D", "SCAF1", "SCAF8", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SENP3", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A2", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMYD3", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAT1", "STAT3", "STAU1", "STAU2", "STK26", "STMN1", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRKH", "TECR", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TLE3", "TM7SF2", "TMCO1", "TMEM109", "TMEM126B", "TMF1", "TMOD1", "TMOD3", "TMPPE", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TST", "TTF1", "TTYH3", "TUFM", "TWNK", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBIAD1", "UBN1", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF3B", "UROD", "USP10", "USP14", "USP19", "USP36", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP3", "UTRN", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VRK1", "VRK2", "WARS", "WARS2", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR5", "WRNIP1", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "ZADH2", "ZC3H13", "ZC3H14", "ZC3H8", "ZC3HAV1", "ZCCHC17", "ZCCHC3", "ZDHHC20", "ZEB2", "ZFR", "ZMPSTE24", "ZNF148", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZRANB2"], "leading_proteins": ["AARS2", "ACADM", "ACOX3", "ADD1", "ADD3", "AIFM1", "AKT2", "ALDH1B1", "ALDH7A1", "ALG1", "ALG13", "ALKBH5", "ARPC3", "ATP13A1", "BAG6", "BRD3", "BUB1B", "BZW2", "CAMK2G", "CARM1", "CDK2", "CDK4", "CDK9", "CHEK1", "CHRAC1", "CLPTM1", "COX4I1", "CYB5R1", "CYFIP1", "DHCR24", "DHFR", "DOCK7", "DPM1", "DSTN", "EEF1A2", "EHMT1", "EHMT2", "EIF2S1", "EIF3D", "EIF3E", "EIF3H", "EIF3J", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF5", "EIF5A", "ELP3", "EMD", "EPB41L3", "ERAP1", "ERMP1", "EXO1", "FAM3C", "FARP1", "FHOD1", "FKBP14", "FKBP2", "FKBP9", "FLAD1", "FLNC", "FOXK1", "FOXRED1", "GAK", "GFM1", "GPX8", "GSTO1", "HDAC1", "HLTF", "HMOX1", "HMOX2", "HOXD11", "HSD17B12", "HSD17B7", "ICMT", "IDH1", "IDH2", "ILK", "IQGAP2", "KDM1B", "KDM2A", "KIAA1147", "KMT2A", "L2HGDH", "L3MBTL3", "LBR", "LIMA1", "LNPK", "MARCKS", "MARCKSL1", "MARS", "ME2", "MGAT1", "MGME1", "MINDY3", "MORF4L1", "MPRIP", "MRPS27", "MTAP", "MTOR", "MYO1D", "NAA15", "NAMPT", "NCOR1", "ND1", "NLN", "NNT", "NPEPPS", "NRDC", "NSUN2", "NT5C2", "NUCB2", "OGDH", "P3H1", "P4HA1", "PAPSS1", "PBK", "PIK3R4", "PLXNB2", "POLR3A", "POLRMT", "PRCP", "PSMB5", "PSMB7", "RAB18", "REXO4", "RIOX1", "RPS6KA3", "SC5D", "SCPEP1", "SEC11A", "SENP3", "SETDB1", "SGF29", "SLFN11", "SLIT2", "SMARCB1", "SMYD3", "SPCS3", "SRPK2", 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overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 154 622 4.714040052746371 2.4285289472736338e-06 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 0.012392742869317 8.287588613988582e-05 1.3031976904093692e-07 3.593051240368391e-11 9.257611542476592e-10 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ffd481e21edafb67246473e9202ae61b415c5726 --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 21, + "title": "Average number of proteins per term", + "value": 473.76190476190476 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d9fd3102ab4f57c72d8c29de5c18ff3436f8e473 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f85279e4ff6cb731a66c8e66250bd1d2bb76357a --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,11 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.3543762904310408 4.714040052746371 2.4285289472736338e-06 5.099786938371848e-05 2.5499553946383654e-05 622 Q9H6V9,Q99720,Q15392,O43772,Q13505,P03886,Q70HW3,Q5BJH7,Q15047,Q8TBP6,Q969V3,Q8IY17,P00846,P41440,Q9UI14,Q5BJF2,O60637,Q9P0I2,Q6P4A7,Q16799,O14653,Q9UBV2,Q9UHQ4,Q9HC07,Q9GZM5,Q53GQ0,P09601,Q05086,Q9BRK0,O60476,A0PJW6,Q92575,P51571,O95168,O43760,Q9P260,Q13423,Q6N075,O60830,Q8WY22,O95831,Q86VD7,Q03518,Q8N2H4,O75964,P33121,Q9C0E8,P50416,O43819,O95249,Q567V2,Q5SWX8,P56134,Q9P0J0,Q9Y5Z9,O15031,P13073,Q16625,Q9H330,P61619,Q92804,Q8IXU6,O43752,Q8WWI5,Q9Y487,O94813,Q15758,Q96J42,Q9Y3B3,O43676,O75381,Q9NUT2,Q9H1A4,Q9UDX5,P38435,Q96KA5,Q9NPR9,Q9Y2J2,Q8N0U8,Q8TDW0,O14681,Q08722,Q96IX5,Q9GZY4,P30519,Q9Y282,Q13586,Q6UW68,P24390,A1L0T0,Q9Y679,Q9C0H2,Q14739,Q9Y3E0,Q9H6K4,Q15070,O60725,Q9NPA0,Q9NPL8,Q9HD20,P51809,O43808,Q9BSK2,O96005,P56937,O60831,O94901,O43657,P30825,P09669,O96011,Q9UM00,Q9BUR5,Q96AA3,P46783,P08574,O75396,Q9UKU0,Q7Z2K6,O75845,O15269,Q96SY0,Q8WXH0,Q13724,Q9NQC3,Q9H3K2,Q96NB2,Q8IXB1,P10620,Q13555,Q16706,Q7L5N7,Q5T4S7,Q9NZ01,Q5JRA6,Q96ES6,O60925,Q9Y619,Q9UH62,Q9NP72,Q6P1Q0,Q8NE01,O15126,P67812,O75717,P51812,O43169,O00400,Q8IZA0,Q93050,Q12907,P26572,P98194,Q8TB61 154 +Transporters 0.2884544492160601 1.707160109208584 0.0877922972037885 0.8547993908589129 0.3072730402132599 388 Q99720,O43772,Q70HW3,Q8TBP6,Q969V3,P41440,Q9UI14,Q5BJF2,O60637,Q9P0I2,Q6P4A7,Q16799,Q9UBV2,Q9UHQ4,Q9HC07,Q9GZM5,A0PJW6,Q6N075,Q8WY22,Q86VD7,Q03518,Q9C0E8,P50416,Q9BRK5,P13073,Q16625,P61619,Q8IXU6,Q9Y371,O43752,Q8WWI5,Q15758,Q9Y3B3,O75381,Q9NUT2,Q96RL7,Q8TDW0,O14681,Q08722,Q9UI26,P14635,Q13586,Q6UW68,P24390,Q9C0H2,Q15070,Q9NPA0,Q9HD20,Q96EE3,O43808,Q9BSK2,O96005,O60831,O94901,P30825,Q9UM00,Q9BUR5,Q96AA3,Q9BQT8,Q96P70,Q9Y5K6,Q96NB2,Q13555,Q99653,O60313,O96008,Q5JRA6,Q9Y619,Q8NE01,O15126,O95782,O00400,Q9NRR5,Q93050,P98194,Q8TB61,Q13277,Q07812,O43865,O00471,Q96PC5,Q8NFH5 82 +FDA approved drug targets 0.3328591953833425 1.3317910628192156 0.1829288555640995 0.9856299811083084 0.4950127473231476 111 Q99720,P03886,Q13547,Q15758,Q02218,P48735,P00374,P38435,Q8N0U8,P49721,P11802,P98194,P28074,Q13423,P09525,Q14145,P42345,P20645,O75874,P50416,P20618 21 +Predicted secreted proteins 0.3506274525636826 1.1981056373468788 0.2308758944868656 0.9959642441654648 0.4950127473231476 54 Q8NDZ4,Q96DX4,Q8WUJ1,Q9H6E4,Q9BUR5,Q92520,P80303,Q9UM22,P43490,Q9UMX5,O94813,Q9HB40,Q8WUY1 13 +Metabolic proteins 0.2418836276330576 0.9719458533401426 0.3310774865946313 0.9997847753198268 0.5793856015406048 869 P11310,Q15392,P49419,O43772,Q03164,P03886,Q70HW3,Q8N4Q0,Q9NPH0,Q15047,Q8IY17,P00846,P41440,Q969T7,P30837,Q9H7B4,P48735,Q9BZK7,Q9NWM8,Q53GQ0,Q86UY6,P09601,Q96K76,P26885,Q05086,O60476,Q9P2R7,P51571,P55786,O95168,O15254,Q13423,Q86VD7,P30520,Q8TD30,Q96PU5,O75964,P33121,P50416,P49005,P34949,Q9C0I1,P56134,Q9P0J0,Q9Y5Z9,P13073,Q99956,O95302,Q86X55,Q9Y371,Q8WWI5,Q9Y487,Q14527,P52888,Q13614,Q15758,Q9NR45,O60502,Q9UKN8,Q13418,O43676,Q96AY3,Q9BRR6,P50750,Q96IX5,P78417,P30519,Q9H0C8,O15228,Q14739,O75874,P35269,O15514,O96000,O43252,Q9UHQ9,O60725,Q96T88,Q96EE3,O43808,P56937,P06132,Q9NYU2,Q9C0C9,Q16718,Q02218,P30825,Q13126,Q9H9P8,P09669,O75414,P00374,Q8TED1,Q7Z2T5,P43490,P13674,P08574,Q9UKU0,Q8NFF5,P11802,O75845,O15269,Q9NVE7,Q9BQT8,Q13724,O75648,O60566,O00411,Q96J02,Q16763,P53701,P23368,P17812,P10620,P61009,Q7LGA3,Q9H773,Q13555,Q16706,Q9Y5P4,Q9BXJ9,Q7L5N7,Q5T4S7,Q9Y5K8,Q9NZ01,Q5JRA6,O75376,Q9Y619,Q9NP73,Q96KQ7,Q15165,Q10713,O60762,O14976,Q9H974,Q9BYT8,P67812,P31751,P30154,Q9UHG3,P78362,P51812,O00400,Q9H9B1,Q93050,P26572,P98194,Q8TB61,P61457,O43865,O15160 151 +RNA polymerase related proteins 0.4631225551097495 0.7861481905908413 0.4317806745506085 0.999993004222234 0.6974918588894445 12 P19387,O15160,O14802,O15514 4 +Disease related genes 0.2203835066452389 0.5233889488899632 0.6007036130210897 0.9999999957615896 0.840882555439846 1000 Q99720,P11310,Q15392,P49419,O43772,Q03164,P03886,Q13432,Q70HW3,Q8IY17,P00846,Q8NC96,Q6P4A7,P48735,Q99575,O14653,Q9BZK7,Q32P28,Q9NWM8,Q9HC07,P14373,P09601,Q05086,Q9BRK0,Q9P2R7,Q9NQT5,P51571,Q13423,Q9NVR5,Q96F07,O95831,Q9NQH7,Q86VD7,Q03518,Q8TD30,Q96PU5,Q96B26,Q9C0E8,Q9UP83,P50416,O43819,P34949,P28070,Q9P0J0,Q9Y5Z9,Q12824,Q9NSE4,P13073,Q16625,P61619,Q92804,Q96RR1,Q15555,Q9NRW7,Q8WWI5,Q96HY6,Q9Y487,Q13614,Q9NR45,Q96J42,O43676,O75381,Q96AY3,Q9H1A4,Q96RL7,Q12955,P38435,O14681,P50750,Q96IX5,P57678,Q86U42,Q15059,Q96DX4,Q14746,Q13586,Q96N67,Q9BQP7,Q9BUK6,Q8N3U4,P83436,O15228,Q14739,Q9UEY8,P07196,O75874,O43791,Q96CU9,Q15427,O95363,Q9H6K4,Q9NPL8,Q8NDZ4,Q96T88,Q6NUQ1,Q9NR56,P06132,Q9BXW9,Q13126,Q9H9P8,O96011,P00374,Q9UM00,Q96AA3,Q13868,P46783,P08574,Q9UKU0,Q8NFF5,P61586,P11802,O75845,O15269,Q9NUQ7,Q9BQT8,Q8WXH0,Q13724,O75648,O60566 119 +Enzymes 0.2242950883394719 0.4643350276279154 0.6424077319558634 0.9999999995820248 0.840882555439846 863 P11310,Q8NB78,Q15392,P49419,Q03164,P03886,P25205,Q8N4Q0,Q9NPH0,Q15047,Q8IY17,Q969T7,P30837,Q9H7B4,P48735,Q99575,Q32P28,Q9NWM8,Q9Y2K7,P14373,P49721,Q53GQ0,Q86UY6,P09601,Q96K76,P26885,Q05086,O60476,Q9P2R7,P28074,P55786,O15254,Q13423,Q9NQH7,P30520,Q8TD30,Q96PU5,P33121,P50416,P34949,P28070,Q9HB40,Q9NSE4,Q96RR1,Q99956,O95302,Q86X55,Q14527,P52888,Q13614,Q9NR45,O60502,Q9UKN8,Q13418,Q96AY3,Q9BRR6,P38435,Q8N0U8,Q9H6W3,P50750,P78417,P30519,Q6P6C2,Q9H0C8,Q9H8M7,O15228,Q14739,O75874,Q2NKX8,O95363,O43847,O43252,Q9UHQ9,O60725,Q96T88,P56937,P06132,Q9C0C9,Q02218,P42785,Q13126,Q9H9P8,O75414,P00374,Q8TED1,P43490,P13674,P08574,Q9UKU0,Q7Z2K6,Q8NFF5,P61586,P11802,O75845,O15269,Q9NZ08,Q9NUQ7,Q13724,O75648,O60566,O00411,Q96J02,Q16763,P53701,P23368,P20618,P17812,P10620,Q9H773,Q13555,Q16706,Q7L5N7,O60313,Q5T4S7,Q9NZ01,Q9NP73,Q15165,Q13547,Q10713,O60762 120 +Human disease related genes 0.2159112460362646 0.386644442726988 0.6990194514026191 0.9999999999887976 0.840882555439846 903 Q99720,P11310,Q15392,P49419,O43772,Q03164,P03886,Q70HW3,Q8IY17,P00846,Q8NC96,Q6P4A7,P48735,Q99575,O14653,Q9BZK7,Q32P28,Q9NWM8,Q9HC07,P09601,Q05086,Q9BRK0,Q9P2R7,Q9NQT5,P51571,Q13423,Q9NVR5,Q96F07,O95831,Q9NQH7,Q03518,Q8TD30,Q96PU5,Q96B26,Q9C0E8,Q9UP83,P50416,O43819,P34949,Q9P0J0,Q9Y5Z9,Q12824,Q9NSE4,Q16625,P61619,Q96RR1,Q15555,Q96HY6,Q9Y487,Q13614,Q9NR45,O43676,O75381,Q96AY3,Q9H1A4,Q96RL7,Q12955,P38435,Q8TDW0,Q96IX5,P57678,Q86U42,Q96DX4,Q14746,Q13586,Q96N67,Q9BQP7,Q8N3U4,P83436,O15228,Q14739,Q9UEY8,P07196,O75874,O43791,Q96CU9,Q15427,O96000,O95363,Q9H6K4,Q9NPL8,Q6NUQ1,P06132,Q02218,Q9P265,Q9BXW9,Q9H9P8,P00374,Q9UM00,Q96AA3,P46783,P08574,P61586,P11802,O75845,O15269,Q9NUQ7,Q9BQT8,Q8WXH0,Q13724,O75648,O60566,Q96J02,Q14145,P53701,Q15021,Q9Y5K6,Q71SY5,P52732,P17812,Q96D71,Q13555,Q9Y5P4,Q9BXJ9,Q99653,O60313 116 +Citric acid cycle related proteins 0.2959577575860007 0.3574479626709898 0.7207564760912966 0.9999999999976792 0.840882555439846 25 O75874,Q9P2R7,P48735 3 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d91f1cdf1fa58c3608172c157bb6b6ac59358c72 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Nuclear receptors", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGA", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BAK1", "BANF1", "BAP18", "BARD1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf35", "C1orf52", "C2CD5", "C3orf58", "C5orf15", "C5orf24", "C5orf51", "C8orf33", "CAAP1", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC59", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPI", "CENPP", "CENPQ", "CENPU", "CENPV", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK1", "CHERP", "CHID1", "CHMP2A", "CHMP6", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CISD3", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC25", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNASE2", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLK", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLEC1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESCO2", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC5", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM114A2", "FAM120A", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM207A", "FAM208A", "FAM208B", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARS2", "FARSA", "FARSB", "FASN", "FASTKD1", "FASTKD2", "FASTKD5", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMC1", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GGCT", "GGCX", "GGH", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH8", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCU", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LETMD1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM12", "LSM2", "LSM3", "LSM4", "LSM5", "LSM6", "LSM7", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "M6PR", "MACF1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED24", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP", "MYDGF", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NENF", "NEPRO", "NES", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN3", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT12", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OSTC", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PGS1", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHRF1", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB32", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF139", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "ROMO1", "RP2", "RPA1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSPRY1", "RSRC1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A3", "SLC35B2", "SLC35F2", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX2", "SNX3", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPEN", "SPOP", "SPOUT1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THEM6", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THYN1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM29", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF3", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED8", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM19", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM223", "TMEM230", "TMEM245", "TMEM33", "TMEM41A", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTF1", "TTLL12", "TTYH3", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBFD1", "UBIAD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "UROD", "USMG5", "USO1", "USP10", "USP14", "USP19", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZCCHC17", "ZCCHC3", "ZCCHC8", "ZDHHC20", "ZEB2", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF148", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF644", "ZPR1", "ZRANB2", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["ABCB8", "ACADM", "ACOX3", "ACP6", "ACSL1", "ACSL6", "ADD3", "ADPGK", "ADSS", "AHCYL1", "AIFM1", "AKT2", "ALDH1B1", "ALDH7A1", "ALG13", "ALKBH5", "ANAPC1", "ANK3", "ANXA4", "AP2A1", "APOO", "ARMCX3", "ATP13A1", "ATP2C1", "ATP5J2", "ATP5L", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "AUP1", "BAX", "BCAP29", "BRD3", "BRI3BP", "BUB1B", "C3orf58", "CAMK2G", "CARM1", "CCDC134", "CCNB1", "CD2AP", "CD47", "CDK4", "CDK9", "CHP1", "CLPTM1", "CLPTM1L", "CNNM3", "COA1", "COG2", "COG5", "COG7", "COL4A3BP", "COX4I1", "COX6C", "CPT1A", "CTPS1", "CYB5B", "CYB5D2", "CYB5R1", "CYC1", "CYFIP2", "DCTPP1", "DDRGK1", "DHCR24", "DHFR", "DIP2B", "DNAAF2", "DNAJC10", "DOCK7", "DPM1", "DUSP9", "EHMT1", "EHMT2", "EI24", "EMC3", "EMC7", "EPB41L3", "EPDR1", "ERAP1", "ERCC6L", "ERGIC3", "ERMP1", "EXOC5", "EXOSC2", "EXOSC3", "EXOSC8", "FAM3C", "FANCD2", "FARS2", "FKBP10", "FKBP14", "FKBP2", "FKBP9", "FLAD1", "FOXRED1", "GAK", "GEMIN4", "GGCX", "GHITM", "GNPAT", "GOLT1B", "GOSR1", "GOSR2", "GPR108", "GPT2", "GPX8", "GSTO1", "GTF2F1", "GTF3C4", "HCCS", "HDAC1", "HLTF", "HMOX1", "HMOX2", "HS2ST1", "HSD17B12", "HSD17B7", "IARS2", "ICMT", "IDH1", "IDH2", "ILK", "ILKAP", "ILVBL", "INTS14", "IPO11", "IPO9", "ITCH", "KDELR1", "KDM1B", "KDM2A", "KEAP1", "KIAA0319L", "KIAA1468", "KIF11", "KMT2A", "L2HGDH", "LBR", "LDAH", "LETMD1", "LMAN2", "LNPK", "LPCAT2", "LRRC8C", "M6PR", "MAN1A2", "MAN2A1", "MAPRE2", "MBNL1", "MCM3", "ME2", "MED25", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST1", "MIA2", "MIA3", "MINDY3", "MOGS", "MPI", "MPV17L2", "MSTO1", "MTAP", "MTFP1", "MTMR12", "MTMR2", "MTOR", "MTX1", "NAA15", "NAA40", "NAMPT", "NANS", "NCAPD2", "NCLN", "NCOR1", "ND1", "NDUFA13", "NDUFA5", "NDUFB10", "NDUFB3", "NDUFB4", "NECAP1", "NEDD4L", "NEFL", "NENF", "NLN", "NME6", "NNT", "NPEPPS", "NRDC", "NT5C3B", "NUCB2", "NUP35", "OCLN", "ODR4", "OGDH", "OPA1", "OPA3", "OXA1L", "P3H1", "P4HA1", "PABPN1", "PANK4", "PAPSS1", "PCBD1", "PCYOX1", "PEX11B", "PEX14", "PFDN1", "PLXNB2", "PMPCA", "PNPLA6", "POLD2", "POLR1C", "POLR2C", "POLR2D", "POLR3A", "POLRMT", "PON2", "POP1", "PPP2R1B", "PRAF2", "PRCP", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "QTRT2", "RAB18", "RABAC1", "REEP2", "REPS1", "RFT1", "RHOA", "RINT1", "RIOX1", "RPS10", "RPS6KA3", "RSPRY1", "RTN1", "RTN4", "SC5D", "SCAMP1", "SCO2", "SCPEP1", "SDF4", "SEC11A", "SEC22B", "SEC61A1", "SEH1L", "SEL1L", "SETDB1", "SF3B4", "SFXN2", "SFXN4", "SH3GLB1", "SIGMAR1", "SLC19A1", "SLC1A5", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A33", "SLC25A40", "SLC25A42", "SLC33A1", "SLC35B2", "SLC35F2", "SLC44A1", "SLC7A1", "SLIT2", "SMARCB1", "SMYD3", "SPCS3", "SPOP", "SPTLC1", "SRPK2", "SSR4", "STAG2", "STIM1", "STX3", "STX6", "SUCLA2", "SUN1", "SYNE2", "SYNGR2", "SYS1", "TAF15", "TAP1", "TBL1XR1", "TECR", "THEM6", "THOP1", "TIMM17B", "TIMMDC1", "TMCO1", "TMED7", "TMEM165", "TMEM205", "TMEM223", "TMEM245", "TMEM97", "TOMM40", "TRIM27", "TRMT1L", "TRMU", "TSPAN3", "TSPAN6", "TTYH3", "TWNK", "TXNDC15", "UBE2O", "UBE2S", "UBE3A", "UBIAD1", "UBQLN4", "UBR4", "UBXN4", "UFSP2", "UGGT1", "UHRF1", "UNC119", "UROD", "USMG5", "USP47", "VAMP7", "VKORC1L1", "VPS13A", "VPS45", "WDHD1", "XPNPEP3", "YIF1B", "YIPF3", "ZADH2"]} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/idx2term.json b/protein_atlas_subcellular_location_all/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..b83d1438c5e8cdb94d8b4594520d3288e0693a4d --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Centriolar satellite"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/plot_0.png b/protein_atlas_subcellular_location_all/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a50f7e336bb4512829d0b5e54a31eddebc337128 --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/plot_0.png @@ -0,0 +1,3 @@ +version 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6.354368932038835 28.046116504854368 0.5330334825095895 0.5754639941794782 3.863025543447266 4.860211896177677 0.8074973811315178 0.3370904262689401 1.0 1.0 0.1030183046019041 0.5418851868443096 0.3403001407786105 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..fcac4dd49a8ca989a552a9b30a86a3893215492b --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3085, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 141.93939393939394 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0dafa358ea5b3271222a3489ab2d8abab46c82d0 --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C180/C180_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1121421054280d286b09730a48afb21bf45d5bc0 --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,13 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Centriolar satellite 0.6070782726708139 2.5183745820383527 0.01178978630724 0.3238731820553809 0.1945314740694606 24 Q9Y5K6,Q9P260,O43169,Q14145,Q03518,Q86YS7,Q15907,Q86UY6 8 +Golgi apparatus 0.3355855246032767 1.8563591176982 0.0634023878442939 0.8848535573842529 0.3422588316840061 173 O95302,Q8IXU6,Q8N4Q0,Q5BJH7,O43752,P80303,Q96J42,O60637,O14653,Q92520,Q9NWM8,Q9NPR9,Q9HC07,Q9GZM5,Q8TDW0,O14681,P09601,O60476,Q6P6C2,Q14746,P40616,O43760,P24390,A1L0T0,P83436,Q9UP83,A4D1U4,Q9BRK5,Q9HB40 29 +Kinetochore 0.6249674064263561 1.3482963743938123 0.177563077785996 0.9984209867570566 0.5984722134597334 3 Q9NQS7 1 +Endoplasmic reticulum 0.2974816177246348 1.3365939461213507 0.1813552161999192 0.9986443378666 0.5984722134597334 208 Q96A57,Q9NZ01,P61619,Q8WUJ1,Q15293,Q99956,O96005,Q96HY6,O60831,Q8IY17,Q5BJF2,Q9P265,Q16799,P29966,Q9UM00,Q96KA5,Q8N0U8,P13674,O14681,O43169,O75845,Q9BRK0,O15269,Q14257,Q92575,P51571,Q13724,Q13586,Q13217,Q9NQC3,Q6UW68,Q96F07,P62841,Q96PC5,Q96CN7,Q03518,Q9C0E8,P10620,P62820,Q9Y3U8,O43852,Q7L5N7,P62263 43 +Rods & Rings 0.5657857928421616 0.7934770714604175 0.4274999228056975 0.9999999898470292 0.9447822901497804 4 Q8WTV0 1 +Mitotic spindle 0.3501638014895844 0.5269975507682187 0.5981952893106635 0.9999999999999144 0.9697540730261373 17 Q9BUF5,Q8WWK9,Q8IX90,Q00610,P11171,P52732,Q9NR09,Q14203,Q68CZ6,P07437,Q9ULW0 11 +Nuclear membrane 0.2580606759761783 0.3471061659643065 0.7285115613897646 1.0 0.9697540730261373 64 Q14739,A0PJW6,P67812,Q96SY0,Q8WXH0,Q13277,O95168,Q9H8M7,Q6UW68,Q8NFH5,O94901,P56134,P11802 13 +Cytoplasmic bodies 0.332937431908942 0.3298433147272244 0.7415183567831618 1.0 0.9697540730261373 14 P26196,O95801,Q9BY77,P78332,P50750,Q92973,P06730,Q99728 8 +Peroxisomes 0.2914064459135783 0.2589314421016679 0.7956881379696572 1.0 0.9697540730261373 17 O75381,O15254 2 +Cytosol 0.1751020443799266 0.2178806840914854 0.8275220774707748 1.0 0.9697540730261373 969 Q96BW9,Q8TBX8,Q9H7D7,P49419,Q9UHD1,O43772,Q03164,Q14166,P26640,Q9UQB8,O00410,Q99615,Q8IY17,Q8NC96,Q92674,P30837,Q6WCQ1,Q9H7B4,Q14141,P78318,P50570,P29372,P23396,Q8TCG1,Q92797,Q9NWM8,Q86WX3,Q9UHQ4,Q6DKJ4,Q1ED39,Q99436,Q9NNW5,Q86UY6,P60520,Q05086,P67809,Q9Y4F1,Q05639,P55786,Q14315,Q9HC38,Q8TB36,Q9P260,Q99426,Q13423,Q9UG56,Q9NVR5,A8MXV4,Q9Y6M1,Q96F07,Q13416,Q9NQH7,Q9Y6E2,O95373,P30520,P61981,Q9UHB6,Q9HCE1,Q9BZF1,P34949,Q3B7T1,Q14558,P54619,P50748,P48147,P24941,P14324,Q9BUP3,Q9P016,Q9Y3C8,Q9H330,P60228,P52292,P00390,Q9Y371,Q4VC44,Q16637,Q8WU90,P52888,Q9UN86,Q96KB5,Q9NTJ3,O60502,O75935,Q9UBQ0,Q13098,P05198,O15372,O43592,O43598,O95071,Q9UJX3,Q9UBB6,P63000,P31350,P50851,P61221,P16989,O14681,Q9UI26,P57678,P30519,Q6P6C2,Q8IZ81,O75155,P14635,P55010,Q6P2C8,P24390,P62841,Q9BUK6,O95456,P49006,O75874,Q2NKX8,Q9UHQ9,Q9H6K4,P46379,Q8WUY1,Q9NR56,P06132,Q9NYU2,Q86YS7,O43657,Q9BXW9,Q13126,Q9BUR5,Q8TED1,P46783,Q8NFF5,P61586,P11802,O75845,Q9H2J4,Q9Y312,Q9NZ08,Q9NUQ7,Q9NVE7,O60566,Q96P70,Q14145,Q15021,Q5TFE4,Q8IX90,Q9Y613,P52732,P17812,Q9H773,Q96D71,Q13555,O75822,Q6P9B9,Q9BXJ9,Q5T4S7,P62263,O96008,Q9NUQ9,O75376,O60925,Q9UH62,Q9NP73,Q8NE01,Q14344,P31751,P30154,P29966,Q9BTE3,P78362,P51812,O43169,O00400,Q7Z7L1,Q96A49,Q93050,Q6PGP7,O94832,A6NDU8,Q92688,Q5VZL5,O15371,P61457,P09525,O43865,Q92973,Q9UJZ1,Q9Y2Z0,Q5VWN6,P51114,P42345,P28161,P09132,O43815,O00178,Q9HAS0,Q9NR33,P62820,Q9Y3U8,P24468,P19387,O95816,O95793,O94979 202 +Actin filaments 0.2335801779247015 0.1771414300568685 0.8593972999957757 1.0 0.9697540730261373 46 P42694,Q96DB5,Q6WCQ1,P49006,Q9HCD5,P17812,Q8TED1,Q5T200,P62312,Q9Y6E2 10 +Cytokinetic bridge 0.2013226348885484 0.0748078625180363 0.9403675859647392 1.0 0.9697540730261373 24 P61201,Q9BUF5,P11171,Q14203,Q68CZ6,Q53HL2,Q6YP21,Q9ULW0,Q96E11 9 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5b7220daf2e934bd0bb0303bc819880f0dafe037 --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABAT", "ABCB1", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD14B", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ADAR", "ADD1", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG13", "ALG2", "ALG5", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFIP1", "ARG2", "ARHGDIA", "ARID1A", "ARID2", "ARID3B", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAHD1", "BAIAP2", "BANF1", "BAP18", "BARD1", "BASP1", "BAZ1B", "BCAP29", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCL2L13", "BCLAF1", "BCOR", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMI1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf35", "C1orf52", "C2CD5", "C5orf15", "C5orf24", "C5orf51", "C8orf33", "CAAP1", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC59", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA5", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPC", "CENPI", "CENPP", "CENPQ", "CENPU", "CENPV", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHID1", "CHMP2A", "CHMP7", "CHORDC1", "CHP1", "CHRAC1", "CHST14", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT9", "CNP", "CNPY2", "COA1", "COA3", "COA7", "COG2", "COG5", "COG6", "COG7", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD10", "COMMD5", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COQ8A", "COQ9", "COTL1", "COX15", "COX4I1", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE2", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF4", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CWC15", "CWC25", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DECR1", "DECR2", "DEK", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC25", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DOLK", "DPF2", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUS2", "DUSP11", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EHMT2", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B3", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELL", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "EMC8", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERBIN", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERH", "ERLIN1", "ERLIN2", "ERP29", "ESCO2", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC6", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FAF1", "FAF2", "FAHD1", "FAM114A2", "FAM120A", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM207A", "FAM208A", "FAM208B", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMC1", "FMR1", "FN3KRP", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCN1", "GDAP1", "GDE1", "GDI2", "GEMIN4", "GEMIN5", "GFM1", "GFM2", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR2", "GOT1", "GPAA1", "GPAM", "GPATCH8", "GPD2", "GPI", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HELLS", "HELZ", "HEXA", "HEXIM1", "HGH1", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLTF", "HM13", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOXD11", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPH1", "HTATIP2", "HTRA2", "HUWE1", "IARS", "IARS2", "IBA57", "ICE2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IFT81", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "ISCU", "ISOC1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KEAP1", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KMT2A", "KMT2B", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LETMD1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLPH", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8C", "LRWD1", "LSM12", "LSM2", "LSM3", "LSM4", "LSM6", "LSM7", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYRM2", "LZIC", "MACF1", "MAEA", "MAGED2", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP4", "MAPK1", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED20", "MED23", "MED25", "MED27", "MED4", "MEPCE", "MESD", "METTL16", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD8", "MGEA5", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPHOSPH8", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEFL", "NEFM", "NELFA", "NELFCD", "NELFE", "NEPRO", "NES", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME6", "NMT1", "NNT", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA1", "NPC1", "NPEPPS", "NPM1", "NR2F2", "NRDC", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C3A", "NT5DC1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDT1", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NUSAP1", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC6", "OSBP", "OSBPL6", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCF11", "PCID2", "PCK2", "PCMT1", "PCNA", "PCNP", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD8", "PEBP1", "PECR", "PEDS1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIAS1", "PICALM", "PIGL", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PNMA8A", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIL3", "PPIL4", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKAA1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN9", "PTRH2", "PUF60", "PUM3", "PUS1", "PWP1", "PWP2", "PWWP2A", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB32", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB8A", "RAB9A", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51AP1", "RAD51C", "RAD54L2", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM23", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOX1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPC3", "RNPEP", "RNPS1", "RP2", "RPA1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSBN1", "RSBN1L", "RSF1", "RSL1D1", "RSL24D1", "RSRC1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC5A6", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX2", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATS2L", "SPC25", "SPCS2", "SPECC1L", "SPEN", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK11IP", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STRN4", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACO1", "TADA3", "TAF15", "TAF6L", "TAF9B", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "THAP11", "THEM6", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THYN1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM23", "TIMM29", "TIMM44", "TIMM50", "TIMMDC1", "TJP1", "TKT", "TLE3", "TLN1", "TM7SF2", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED8", "TMEM109", "TMEM126A", "TMEM126B", "TMEM165", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM223", "TMEM230", "TMEM245", "TMEM41A", "TMEM70", "TMEM97", "TMF1", "TMOD3", "TMPPE", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT1L", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TST", "TTC1", "TTC19", "TTC37", "TTC4", "TTF1", "TTLL12", "TUBB", "TUBB2B", "TUBB6", "TUBGCP2", "TUFM", "TWISTNB", "TXLNA", "TXLNG", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA6", "UBAC2", "UBAP1", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBFD1", "UBIAD1", "UBN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF3B", "UQCC1", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "UROD", "USMG5", "USO1", "USP10", "USP14", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WASHC4", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR36", "WDR41", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR77", "WDR82", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YES1", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H8", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZDHHC20", "ZEB2", "ZFR", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF148", "ZNF280C", "ZNF281", "ZNF318", "ZNF326", "ZNF346", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF644", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAR2", "ABCE1", "ACOX3", "ADSS", "AHCYL1", "AKT2", "ALDH1B1", "ALDH7A1", "ALG13", "ALKBH5", "ANAPC7", "ANP32B", "ANXA4", "APOO", "ARL1", "ARMCX3", "ATP5J2", "ATP6V0A1", "BAG2", "BAG6", "BAIAP2", "BARD1", "BCAP29", "BIRC6", "BUB1B", "BZW2", "C17orf75", "C2CD5", "C5orf51", "CALU", "CAMK2G", "CAND2", "CCNB1", "CD2AP", "CDCA8", "CDK2", "CDK4", "CDK9", "CENPI", "CHORDC1", "CIP2A", "CKAP2", "CLPTM1", "CLPTM1L", "CLTC", "CNNM3", "COG2", "COG5", "COG7", "COPS2", "CTPS1", "CYB5B", "CYB5D2", "CYB5R1", "CYFIP2", "DCTN1", "DCTN3", "DCTPP1", "DDRGK1", "DDX6", "DIP2B", "DNAAF2", "DNAJC3", "DNAJC7", "DNM2", "DNPH1", "DUSP9", "EDRF1", "EEF1A2", "EI24", "EIF2S1", "EIF3D", "EIF3E", "EIF3H", "EIF3J", "EIF4E", "EIF5", "ELMOD2", "EPB41", "ERAP1", "ERCC6L", "FAM208B", "FAM3C", "FAM49B", "FANCD2", "FARP1", "FDPS", "FHOD1", "FKBP14", "FKBP9", "FLAD1", "FLNC", "FLYWCH1", "FXR1", "G3BP2", "GABARAPL2", "GDAP1", "GEMIN4", "GLOD4", "GNA13", "GOSR2", "GPR108", "GPS1", "GPX8", "GSR", "GSTM2", "GTPBP1", "HAUS3", "HELZ", "HMOX1", "HMOX2", "HTATIP2", "IDH1", "IGBP1", "IGF2BP2", "ILVBL", "INCENP", "INTS14", "INTS5", "IPO11", "IPO5", "IPO7", "IPO9", "ISOC1", "KDELR1", "KEAP1", "KIAA1147", "KIAA1468", "KIF11", "KMT2A", "KNOP1", "KNTC1", "KPNA2", "KYAT3", "LBR", "LIMA1", "LNPK", "LPCAT2", "LRBA", "LRRC8C", "LSM6", "MAN1A2", "MARCKS", "MARCKSL1", "MBNL1", "MCMBP", "MED27", "MGEA5", "MGST1", "MIA2", "MINDY3", "MOGS", "MOV10", "MPG", "MPI", "MPRIP", "MRRF", "MSTO1", "MTAP", "MTOR", "MYO1D", "NAA15", "NAA40", "NCAPD2", "NCDN", "NCOA5", "NCOR1", "NDUFB4", "NECAP1", "NNT", "NPEPPS", "NR2F2", "NT5DC1", "NUCB2", "NUDT19", "NUP35", "NXN", "OPA3", "ORC2", "OSBPL8", "P4HA1", "PANK4", "PBK", "PCBD1", "PDCL3", "PEX14", "PFDN1", "PIP4K2C", "PISD", "PNPLA6", "POLDIP3", "POLE4", "POLR2C", "PPP2R1B", "PRAF2", "PREP", "PRKAG1", "PRPSAP1", "PSMB7", "PSMG1", "RAB11B", "RAB1A", "RAC1", "RBM6", "RCN1", "RCN2", "REEP2", "REPS1", "RHOA", "RMDN1", "RPL36", "RPS10", "RPS14", "RPS15", "RPS19BP1", "RPS3", "RPS6KA3", "RRM2", "RTN1", "RTN4", "SC5D", "SCARB1", "SCPEP1", "SDF4", "SEC11A", "SEC31A", "SEC61A1", "SEPT6", "SH3GLB1", "SKA3", "SLC25A20", "SLC33A1", "SLC35F2", "SLFN11", "SMC4", "SMN1*", "SMYD3", "SPTLC1", "SRP19", "SRPK2", "SSR4", "STAU1", "STIM1", "STOML2", "STRN", "STX3", "STX6", "SUGT1", "SUN1", "SYAP1", "SYMPK", "SYNE2", "SYNGR2", "TAMM41", "TAP1", "TBCB", "TECR", "THEM6", "THOP1", "THYN1", "TMCO1", "TMEM165", "TMEM205", "TMEM223", "TMEM230", "TMEM245", "TMEM97", "TNPO1", "TOMM40", "TPX2", "TSPAN3", "TSPAN6", "TTC37", "TTC4", "TTLL12", "TUBB", "TUBB6", "TXNDC15", "UBE3A", "UBR4", "UBR5", "UBXN4", "UFC1", "UFSP2", "UGGT1", "UROD", "VARS1", "VKORC1L1", "VPS29", "WDR26", "WDR6", "XPNPEP3", "XPOT", "YBX1", "YBX3", "YIF1B", "YIPF3", "YWHAG", "ZADH2", "ZC3H13", "ZC3H15", "ZMYM4"]} \ No newline at end of file