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c6a6edd verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Eukaryotic translation initiation 0.4928050531559154 4.3240099899688245 1.532183533270448e-05 0.020727283998661 0.0209449488998083 97 Q04637,P62701,P15880,P62081,P61254,P62829,O15371,P62280,P23588,P62244,P62273,P83881,P05198,P62249,Q14232,P61353,Q9UI10,P60842,Q9NR50,P62913,P46777,P18621,P06730,P62753,Q14240,P62263,P23396,P61513,P61927,P62841,P18124,P61313,P62906,P84098,P60228,P62847,P39023,Q02878,P60866,P63220,P62241,P62750,Q13347,P46783,P18077,P08865,Q9Y262,P55010,P27635,P46776,P25398,P32969,P62851,Q14152,P08708,P46779,Q7L2H7,Q9Y3U8,P83731,Q02543,P11940,P62266,P35268,P26373,O75822,O15372 66
Regulation of expression of slits and robos 0.472262720253775 4.048893876503308 5.1460271111691824e-05 0.0679305973336289 0.035173095304842 120 P28072,P49720,P60900,Q04637,P62701,P28074,P62081,P61254,P62829,P62280,P15880,P62195,Q99460,P49721,P62244,P28070,P62273,P83881,P61353,P48556,O00232,P52298,P18621,P62913,P62753,Q15370,P62263,P23396,P61513,O75832,P61927,P62841,P18124,O43242,P61313,P51665,Q9UL46,P84098,P62847,P39023,Q02878,P60866,P63220,P62241,O94813,P62750,O00487,P46783,P18077,P08865,P27635,P20618,P62495,P46776,P25398,P32969,P62851,Q15369,P08708,P46779,Q9Y3U8,O00231,Q99436,P83731,Q02543,P25788,P62266,P35268,P11940,Q15008,Q13617 71
S phase 0.4636376757525238 3.940347408696227 8.136369205957728e-05 0.105265893087759 0.0370747223484811 94 P28072,P49720,P60900,P28074,P11802,P49005,P40938,Q99460,P49721,P30260,P28070,P33993,P31751,Q13309,P24941,P48556,Q7Z5K2,Q9NR33,Q14181,O43242,P41440,P51665,Q9UBD5,Q9UL46,P33992,Q9Y619,Q16763,P28340,P20618,P25205,Q9BRT9,Q9BRX5,Q9H1A4,P27694,O00231,Q99436,P25788,P56282,Q5TKA1,P33991 40
Signaling by robo receptors 0.4518816999637663 3.845805340263377 0.0001201571292877 0.1514825804652291 0.0410636989340722 132 Q04637,P62701,P62081,P61254,P49721,P28070,Q7Z460,P61353,O00232,P61513,P63000,O43242,P84098,P62847,O94813,P62750,O00487,P46783,P08865,P27635,P25398,P32969,P62851,P46779,O00231,Q02543,P26373,P35080,P28072,P62829,P62280,P48556,P18621,P62753,P62263,Q9UL46,P60866,P63220,P20618,P62495,Q99436,Q16512,P25788,P60900,P28074,P07737,Q99460,P52298,Q15370,P62841,P51665,P39023,P62241,P61586,P46776,P62266,P35268,P49720,P15880,P62195,P62244,P62273,P83881,P62913,P23396,O75832,P61927,P18124,P61313,Q02878,P18077,Q15369,P08708,Q9Y3U8,P83731,P11940,Q15008,Q13617 78
Nervous system development 0.3683915146066334 3.2519134063298742 0.0011463093956747 0.7915182490689575 0.115650066005543 193 Q04637,P62701,P62081,P61254,P49721,P28070,Q7Z460,P61353,O00232,P61513,P63000,O43242,Q92769,P84098,P62847,O94813,P62750,O00487,P46783,P08865,P27635,Q00535,P25398,P32969,Q92747,Q9BUF5,P19784,P62851,Q9NR77,P46779,O00231,Q02543,P35241,P26373,P35080,P28072,P67870,P62829,P62280,Q9BVA1,P48556,P18621,P51812,P62753,P62263,Q9UL46,P46939,P60866,P63220,P20618,P62495,Q9BPU6,Q99436,Q16512,P25788,P60900,P28074,P07737,Q99460,P52298,P62993,Q15370,P62841,P51665,P13591,P39023,P62241,Q96S59,Q15375,P61586,P46776,Q96CW1,P62266,P35268,P49720,P15880,P62195,P62244,P62273,P83881,P62913,P23396,O75832,O00459,P07900,Q96P70,P61927,P18124,P61313,P06756,Q02878,O15145,P18077,Q15369,P50570,P08708,Q9Y3U8,P83731,P11940,Q15008,Q13617,P23528 102
Class i mhc mediated antigen processing presentation 0.410828075500484 3.136059835307292 0.0017123426365768 0.9039396632497084 0.115650066005543 104 P28072,P49720,P60900,P28074,Q9UIQ6,Q5T4S7,P49721,P30260,P28070,Q9UBG0,Q05086,P10321,P52888,P04439,P55786,P06756,Q96PU5,Q16763,Q9C0C9,Q9NZ08,P20618,Q15369,Q14669,Q9H1A4,P25788 25
Adaptive immune system 0.3791297926141012 3.1212459678110167 0.0018008754741982 0.9149074790651476 0.115650066005543 168 P28072,P49720,P30153,P60900,P28074,Q9UIQ6,P53634,P41240,Q5T4S7,P49721,P30260,P28070,P31751,Q9UBG0,Q05086,P42345,Q5KU26,Q9BVA1,P10321,Q13309,P48556,P78310,P04439,P52888,O00459,P55786,P30154,O43242,Q99538,P06756,Q96PU5,O94979,Q9UJW0,Q07866,Q9BXS5,Q96J02,Q16763,Q9C0C9,Q9NZ08,Q13586,P20618,Q9BUF5,Q15369,Q14669,P50570,Q9H1A4,O00231,P25788,P47755,Q13617 50
Innate immune system 0.3269930552874037 3.098751245925507 0.0019433811440481 0.9299948710119657 0.115650066005543 261 P28072,P67870,P49720,Q9UQB8,P30153,P60900,P17858,P28074,P09110,P53634,Q5T4S7,P49721,Q93050,P28070,O15126,Q96F07,Q9Y376,P07437,P42785,O00571,Q15366,P10321,Q14019,Q8N1F8,P11717,P04439,P04114,O00459,P09960,P30154,O43242,O00754,Q99538,P06756,Q8WVQ1,Q8IV08,P06280,O00584,P61916,P78371,Q13526,Q9BXS5,Q7L576,P27105,Q9Y487,O75874,O15145,Q96J02,Q04656,P20618,P61586,Q92747,Q96CS3,P04066,P50570,P02792,P15586,Q9BTY2,Q9NQX7,Q99570,O00231,P16278,Q99536,P30519,P25788,O14802,P07686,O43681,O15160,P09601,P07602 71
Hs gag degradation 0.9518229166666652 2.9586863759895996 0.0030895335400855 0.985446590376057 0.115650066005543 2 P16278 1
Mucopolysaccharidoses 0.9521328557473132 2.9436330042535785 0.0032438440635171 0.9882222435327974 0.115650066005543 3 P16278,P15586 2
Transport of small molecules 0.372066973669438 2.9429020527005747 0.0032515127406564 0.9883454638989166 0.115650066005543 163 P28072,P49720,Q9UNS2,P60900,Q70HW3,P28074,Q9Y2D2,Q9C0H2,P49721,P28070,P08183,P51790,P04114,P02786,Q8WTV0,Q9HD20,Q96PU5,P11166,P61916,P27105,P35670,Q9Y487,P01130,O00400,P20618,Q96TA2,P02792,Q9UEY8,P30519,P25788,P30825,P09601,O15118 33
Formation of fibrin clot clotting cascade 0.9453124999999948 2.931854474437324 0.0033694459484543 0.9900860257396884 0.115650066005543 2 P42785 1
Intrinsic pathway of fibrin clot formation 0.9453124999999948 2.931854474437324 0.0033694459484543 0.9900860257396884 0.115650066005543 2 P42785 1
Chylomicron clearance 0.9449869791666634 2.930510588936714 0.0033840546014789 0.9902827018440774 0.115650066005543 2 P01130 1
Scavenging by class b receptors 0.9449869791666624 2.930510588936714 0.0033840546014789 0.9902827018440774 0.115650066005543 2 Q8WTV0 1
Selenoamino acid metabolism 0.456935341710205 2.8221116121595418 0.0047708570265445 0.998551705193014 0.132203989695063 87 P62701,P15880,P62081,P61254,P62829,P62280,P62244,P62273,P83881,P62249,P61353,P62913,P56192,P46777,P18621,P62753,O43324,P23396,P62263,P61513,P47897,P61927,P62841,P18124,P61313,P62906,P84098,P07814,Q13155,P62847,P39023,Q02878,Q9P2J5,P63220,P60866,P62241,P62750,P46783,P18077,P08865,P27635,P46776,P25398,P32969,P62851,P08708,O43252,Q16881,P46779,Q9Y3U8,P83731,Q02543,P62266,P35268,P26373 55
Regulation of gene expression in beta cells 0.9130859374999908 2.797742187146623 0.0051461170675466 0.999135107359925 0.132203989695063 2 P31751 1
Constitutive signaling by akt1 e17k in cancer 0.9088541666666572 2.779970014659231 0.0054363918022863 0.99941961652394 0.132203989695063 2 P31751 1
Endosomal vacuolar pathway 0.9039400846629736 2.741983025924182 0.0061069497346979 0.9997691622710472 0.132203989695063 3 Q9UIQ6,P10321 2
Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.8883463541666676 2.693306485218731 0.0070747201457339 0.9999390535510618 0.1362459815667299 2 Q9Y624 1
Keratan sulfate keratin metabolism 0.8986457464879158 2.687359005488747 0.0072019500264639 0.9999488469613842 0.1362459815667299 5 P06865,P15586,O43505 3
Dna replication 0.4563626152467606 2.648085971772129 0.008094893641853 0.999985049274028 0.1430412804137417 86 P28072,P49720,P60900,P28074,P49005,P62195,P40938,Q99460,P49721,P30260,P28070,P33993,Q13309,P24941,P48556,Q9NR33,Q14181,O75832,O43242,P41440,Q14566,P51665,Q9UL46,Q9UBD5,P33992,P49642,Q9Y619,Q16763,P28340,P49643,P20618,P49736,P25205,Q9BRT9,Q9BRX5,P16104,Q9H1A4,P27694,O00231,Q99436,P25788,P40937,P56282,Q9UJX3,Q9Y2S7,P33991 46
Separation of sister chromatids 0.3777884408928673 2.6445392924714044 0.0081802208656085 0.9999867080236292 0.1430412804137417 102 P28072,Q96EE3,P30153,P60900,P50748,P49720,P28074,Q53HL2,O43264,P43034,Q99460,P49721,P30260,P28070,Q7Z460,Q12769,Q9BVA1,P48556,Q7Z5K2,P57740,P30154,O43242,Q2NKX8,P51665,Q9UL46,Q96IY1,Q6IPU0,Q6P1K2,Q16763,P20618,Q9BUF5,O14980,O43684,Q9H1A4,Q9BZD4,O60566,O00231,Q99436,P25788,Q9UJX3 40
Mitotic g1 phase and g1 s transition 0.5766801209438093 2.616072187017123 0.00889477505422 0.999995037281112 0.1430412804137417 76 P28072,P49720,P30153,P60900,P28074,P06493,Q99460,P49721,P28070,P33991,P33993,P31751,P04818,Q13309,P24941,P48556,Q9NR33,P63151,Q14181,P42771,P31350,P30154,O43242,P51665,Q9UL46,Q9UBD5,P33992,P14635,Q9Y619,P20618,P25205,P00374,P04183,P56282,Q99436,O00231,P25788,P27694,Q5TKA1,P11802 40
Pi3k akt activation 0.861328125000002 2.5777610558044515 0.0099442735109838 0.9999988339209668 0.1477589335816834 2 P61586 1
Keratan sulfate degradation 0.8674705704163448 2.56894994914439 0.0102007189395711 0.9999991816629512 0.1499395998967078 4 P06865,P15586 2
Cd28 dependent pi3k akt signaling 0.8616085965483515 2.560820068836837 0.0104425423947847 0.9999994140385556 0.1518612282305393 3 P42345,P31751 2
G beta gamma signalling through pi3kgamma 0.8552856633382383 2.533431816587304 0.011295171228892 0.9999998196493564 0.1544212682277377 3 P31751 1
Fructose metabolism 0.8424479166666623 2.496086992049095 0.012557180217763 0.999999968533815 0.1634825272160203 2 Q00796 1
Cs ds degradation 0.8365885416666505 2.470583496896311 0.0134892824382686 0.9999999913469082 0.1699547542858552 2 P06865 1
Hyaluronan metabolism 0.8371335504885898 2.4365392977943134 0.0148285581213789 0.9999999986490172 0.1747468875165951 4 Q99653,Q9UHD1,P06865 3
Hyaluronan uptake and degradation 0.8371335504885898 2.4365392977943134 0.0148285581213789 0.9999999986490172 0.1747468875165951 4 Q99653,Q9UHD1,P06865 3
Diseases associated with glycosaminoglycan metabolism 0.8371335504885895 2.4365392977943134 0.0148285581213789 0.9999999986490172 0.1747468875165951 4 Q8NCH0,O94766,P06865 3
Mastl facilitates mitotic progression 0.831270358306185 2.410722133200924 0.0159209729022076 0.9999999997035324 0.1844404233671001 4 P30154,P30153,P14635 3
Heparan sulfate heparin hs gag metabolism 0.8325775188374548 2.3995292699639847 0.0164161673185994 0.9999999998510096 0.187019525449827 5 P16278,P54802,Q7LGA3 3
O linked glycosylation of mucins 0.8202539889286825 2.380135864242081 0.0173062559131196 0.9999999999567816 0.1923386327905246 3 Q86SF2,O43505 2
O linked glycosylation 0.820521172638425 2.36320062945382 0.0181178581835763 0.9999999999860316 0.1939756029941371 4 Q9Y2G5,Q86SF2,O43505 3
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.808968641132207 2.3301922523860967 0.01979599228409 0.9999999999986522 0.2022808325738929 3 Q5TKA1 1
Role of abl in robo slit signaling 0.8088298556010843 2.329576361645503 0.0198285527175579 0.999999999998712 0.2022808325738929 3 O94813 1
Crmps in sema3a signaling 0.8004392878581492 2.2922652704982993 0.0218903405786825 0.9999999999999276 0.2055496857547392 3 Q9BPU6 1
Role of phospholipids in phagocytosis 0.8001858192226907 2.291135821363751 0.0219555594248319 0.999999999999934 0.2055496857547392 3 Q8IV08 1
Sialic acid metabolism 0.803725193456345 2.288456128258878 0.0221109722038492 0.9999999999999468 0.2055496857547392 4 P16278 1
Synthesis of dna 0.4865621765634235 2.2883600103966986 0.0221165644335041 0.9999999999999472 0.2055496857547392 81 P28072,P49720,P60900,P28074,P49005,P62195,P40938,Q99460,P49721,P30260,P28070,P33993,Q13309,P24941,P48556,Q9NR33,Q14181,O75832,O43242,P41440,Q14566,P51665,Q9UL46,Q9UBD5,P33992,P49642,Q9Y619,Q16763,P28340,P49643,P20618,P49736,P25205,Q9BRT9,Q9BRX5,Q9H1A4,P27694,O00231,Q99436,P25788,P40937,P56282,Q9UJX3,Q9Y2S7,P33991 45
Cellular response to starvation 0.4268350528674998 2.286769218481916 0.0222092970621674 0.9999999999999536 0.2055496857547392 86 Q96EE3,P62701,P15880,P62081,P61254,P62829,P62280,P62244,P62273,P83881,P05198,P62249,P42345,P61353,P62913,P46777,P18621,P62753,P23396,P62263,P61513,P61927,P62841,P08243,P18124,P61313,P84098,P62847,P39023,Q02878,P60866,P63220,P62241,P62750,P46783,P18077,Q92616,P08865,P27635,P46776,P25398,P32969,P62851,P08708,P46779,Q9Y3U8,P83731,Q02543,P62266,P35268,P26373 51
Heme degradation 0.8000297478187351 2.2719309892387884 0.0230906788358651 0.9999999999999865 0.2075123015754063 4 P30519,P09601 2
Bmal1 clock npas2 activates circadian gene expression 0.7986394880385529 2.265706659008973 0.0234693495639519 0.999999999999992 0.2083285769735217 4 P43490,Q9BZK7 2
Aryl hydrocarbon receptor signalling 0.7901865269359654 2.2464707556872328 0.0246738706772813 0.9999999999999986 0.2106812032737695 3 Q15185 1
Irs mediated signalling 0.7920860567736401 2.236311791572603 0.0253313545847428 0.9999999999999994 0.2106812032737695 4 P31751,Q99570 2
Transport of connexons to the plasma membrane 0.7832031249999998 2.2348119193554106 0.0254296990052464 0.9999999999999994 0.2106812032737695 2 Q9BUF5 1
Gap junction assembly 0.7832031249999998 2.2348119193554106 0.0254296990052464 0.9999999999999994 0.2106812032737695 2 Q9BUF5 1
Carboxyterminal post translational modifications of tubulin 0.7834581569521306 2.216297685170015 0.0266711214659849 1.0 0.2191565552052351 3 Q14166,Q9BUF5 2
Platelet sensitization by ldl 0.7743192575803424 2.1561713310410378 0.0310702892695724 1.0 0.2213948638407561 4 P04114,P30153 2
Stimuli sensing channels 0.7909003665238215 2.143927922947604 0.0320386624511357 1.0 0.2213948638407561 10 Q96PU5,P51790,Q9C0H2 3
Myoclonic epilepsy of lafora 0.7623697916666584 2.1411556572146484 0.0322614875948494 1.0 0.2213948638407561 2 P13807 1
Regulation of tlr by endogenous ligand 0.7587890624999788 2.124967131161664 0.0335893556333202 1.0 0.2213948638407561 2 P04114 1
Glycosaminoglycan metabolism 0.7936306905758451 2.1110022449878425 0.0347721188987193 1.0 0.2213948638407561 15 O43505,P06865,P15586,O43252,P16278,Q99653,Q8NCH0,P54802,Q9UHD1,Q7LGA3 10
Insulin receptor signalling cascade 0.7648897797370982 2.095118633039817 0.0361604479538462 1.0 0.2213948638407561 5 P31751,Q99570 2
Hs gag biosynthesis 0.7516276041666525 2.0925107036834345 0.0363928552708561 1.0 0.2213948638407561 2 Q7LGA3 1
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.764084686285188 2.091441506571191 0.036488504733638 1.0 0.2213948638407561 5 P31751,Q99570 2
Metabolism of cofactors 0.7601377412337411 2.07339593897393 0.0381354465778196 1.0 0.2213948638407561 5 P00374 1
Transport of nucleotide sugars 0.746744791666657 2.0703210990781193 0.0384222850364857 1.0 0.2213948638407561 2 Q9Y2D2 1
Ngf stimulated transcription 0.7501020337015994 2.06532709950245 0.0388920611300989 1.0 0.2213948638407561 3 P50570 1
Cell cycle mitotic 0.2924740402546282 2.0544396006528927 0.0399331635738047 1.0 0.2213948638407561 241 Q96EE3,Q14739,P06493,P49721,P28070,P31751,Q7Z460,P07437,Q9H6D7,P62826,O43242,P41440,Q9UBD5,Q7Z4H7,Q9Y619,Q6IPU0,Q6P1K2,P28340,P62140,Q9BRT9,Q9BUF5,P00374,O00231,P56282,Q8TD19,P28072,P67870,P50748,P49005,P40938,P33993,Q9BVA1,Q13309,P48556,Q7Z5K2,Q9NR33,Q14181,Q9NTJ3,Q9UL46,P33992,P41208,P50402,Q16763,P20618,P25205,O14980,Q9H1A4,P04183,Q99436,P25788,O94927,P27694,Q92973,P33991,P30153,P60900,P28074,Q99460,Q9BSJ2,Q12769,P04818,P24941,P31350,P14635,Q96CW5,Q9BRX5,Q86Y07,Q9Y6X3,Q9BZD4,Q5TKA1,P11802,P49720,Q53HL2,P30260,P63151,P42771,P30154,Q2NKX8,Q96IY1,O60566 80
Antigen processing ubiquitination proteasome degradation 0.4526133519327911 2.041388364512332 0.0412122400672965 1.0 0.2239528852383566 82 P28072,P49720,P60900,P28074,Q9UIQ6,Q5T4S7,P49721,P30260,P28070,Q05086,P52888,P55786,Q96PU5,Q16763,Q9C0C9,P20618,Q15369,Q14669,Q9H1A4,P25788 20
Ptk6 regulates cell cycle 0.7402343750000028 2.0406597602375567 0.0412846577030474 1.0 0.2239528852383566 2 P11802 1
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.7402343750000028 2.0406597602375567 0.0412846577030474 1.0 0.2239528852383566 2 P11802 1
Tie2 signaling 0.7382812500000069 2.031744732342581 0.0421795048617335 1.0 0.2261152280235044 2 O00459 1
Interleukin receptor shc signaling 0.7382812500000069 2.031744732342581 0.0421795048617335 1.0 0.2261152280235044 2 O00459 1
Gab1 signalosome 0.738281250000001 2.031744732342552 0.0421795048617363 1.0 0.2261152280235044 2 P41240 1
Signalling to ras 0.7301432291666644 1.9945170799168124 0.0460955753104288 1.0 0.2414277833308668 2 P62993 1
G protein beta gamma signalling 0.7403852247102192 1.9826307807153776 0.0474086865460834 1.0 0.2432476585299753 5 P31751 1
Formation of xylulose 5 phosphate 0.7316834907196291 1.981002276296079 0.0475910183148595 1.0 0.2432476585299753 3 Q00796,Q7Z4W1 2
Raf independent mapk1 3 activation 0.7284480187146245 1.966121193028952 0.0492846128686441 1.0 0.2489091338250499 3 Q99956 1
Glycogen synthesis 0.7326253216759109 1.9656000820575033 0.0493448246280823 1.0 0.2489091338250499 4 P13807 1
Nonsense mediated decay nmd 0.421722420108735 1.9416370424223763 0.0521810552360273 1.0 0.2584474728538021 84 P30153,Q04637,P62701,P15880,P62081,P61254,P62829,P62280,P62244,P62273,P83881,P61353,P52298,P18621,P62913,P63151,P62753,P23396,P62263,P61513,Q92900,P62841,P61927,P18124,P61313,P84098,P62847,P39023,Q02878,P60866,P63220,P62241,P62750,P46783,P18077,P08865,P27635,P62495,P46776,P25398,P32969,P62851,P08708,P46779,Q9Y3U8,P83731,Q02543,P11940,P62266,P35268 50
Pp2a mediated dephosphorylation of key metabolic factors 0.7193112512225199 1.9239906215356457 0.0543557590293097 1.0 0.2634045431059919 3 P30153 1
Ctla4 inhibitory signaling 0.7298460106384826 1.915840004664504 0.0553854639658193 1.0 0.2656558920746492 6 P30153,P31751 2
Phosphorylation of emi1 0.7149996270353062 1.9040551077411911 0.0569030074919221 1.0 0.2697979367137829 3 P14635 1
G alpha 12 13 signalling events 0.7121886930502148 1.870974333972387 0.0613486385978343 1.0 0.2786165746287029 4 P61586 1
Activated tak1 mediates p38 mapk activation 0.7018229166666665 1.8639688386242457 0.0623260804861725 1.0 0.2793434492609764 2 P61088 1
Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.7018229166666665 1.8639688386242457 0.0623260804861725 1.0 0.2793434492609764 2 P61088 1
The activation of arylsulfatases 0.7014973958333297 1.862459601456665 0.0625383347433095 1.0 0.2793787699153728 2 O43681 1
Scavenging by class a receptors 0.7128303282257227 1.8547970245688432 0.0636252171108084 1.0 0.2824695345777953 5 P04114,Q5KU26 2
Maturation of sars cov 2 nucleoprotein 0.7081026380186479 1.8519650719059928 0.0640308386460519 1.0 0.2832691146574532 4 Q99873,Q96SB4 2
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.7020514490393972 1.843984260068592 0.0651854340854847 1.0 0.2865224707230178 3 P61088,P09429 2
Nod1 2 signaling pathway 0.7020514490393961 1.8439842600685872 0.0651854340854853 1.0 0.2865224707230178 3 Q96J02,P61088 2
Metabolism of porphyrins 0.7187959094717349 1.833577124592238 0.0667167904416996 1.0 0.2923136299160366 8 P30519,P50336,P53004,P09601 4
Activation of nima kinases nek9 nek6 nek7 0.7033434144287691 1.8297876696650144 0.0672816952994166 1.0 0.2924287921435437 4 P06493,P14635 2
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.7107505094379399 1.8267148670174056 0.0677426517436643 1.0 0.2924287921435437 6 P78310,Q5KU26,P10321 3
G1 s specific transcription 0.7228846334212712 1.825555740204872 0.0679172078048071 1.0 0.2924287921435437 10 P00374,Q9Y619,P31350,P04818,Q5TKA1 5
Metabolism of amino acids and derivatives 0.3012951708200071 1.8250566781156456 0.0679924767630193 1.0 0.2924287921435437 190 Q96H78,P28072,P49720,O75746,Q9UBQ7,P60900,P28074,P08195,P15880,Q99707,P62829,P62280,O00330,P62195,Q99460,P49721,Q9BQT8,P28070,Q9BV20,P62244,P62273,P83881,P61353,P48556,P62913,P18621,P62753,O43324,O43708,P62263,P23396,P61513,O75832,P61927,P62841,P08243,P18124,O43242,Q13126,P61457,P51665,Q9UL46,O75600,P84098,Q13155,P62847,P39023,P21953,Q9P2J5,Q9Y619,P63220,P60866,Q16762,P62241,P46783,P27635,P20618,P46776,O15382,O43175,Q9NR77,P08708,O43252,Q16881,P46779,Q9Y3U8,O00231,Q99436,Q9BV57,P83731,P25788,P62266,P35268,P19623 74
Diseases of carbohydrate metabolism 0.7195150462892266 1.822850306413185 0.0683260660745159 1.0 0.2924287921435437 9 P16278,P54802,P15586 3
Constitutive signaling by ligand responsive egfr cancer variants 0.694236405079774 1.8075851309200333 0.0706710941390387 1.0 0.2975217701204445 3 Q16543,P62993 2
Signaling by egfr in cancer 0.694236405079774 1.8075851309200333 0.0706710941390387 1.0 0.2975217701204445 3 Q16543,P62993 2
Constitutive signaling by egfrviii 0.694236405079774 1.8075851309200333 0.0706710941390387 1.0 0.2975217701204445 3 Q16543,P62993 2
Response of eif2ak1 hri to heme deficiency 0.6890862347367295 1.783541366735893 0.0744982204229411 1.0 0.3049073871801215 3 P05198 1
Synthesis of pips at the early endosome membrane 0.6969993194046733 1.780757270638319 0.0749521126532846 1.0 0.3049391011816668 5 Q13614,Q9C0I1 2
Vesicle mediated transport 0.2840948206719037 1.7691119845038168 0.0768751883053633 1.0 0.3109123740042357 227 Q9H3P7,Q9UNS2,O00743,P24390,Q9UIQ6,P53634,P31751,O14976,O60499,Q9UP83,Q5KU26,O75976,P11717,P04114,O60476,P02786,Q8WTV0,Q92905,Q14108,O15027,Q9UJW0,Q15102,O43731,Q8NC96,P01130,Q92734,Q92538,O00461,Q7Z392,P02792,P15586,Q13637 32
Carnitine metabolism 0.6930867872155646 1.7437400179855784 0.0812044339256845 1.0 0.3245802958374584 6 P23786 1
Post chaperonin tubulin folding pathway 0.6938376263449677 1.7310337375010325 0.0834457473450043 1.0 0.3306386568713649 7 Q9BUF5,Q15813,Q9BTW9,Q9BVA1,Q99426,O75347 6
Methionine salvage pathway 0.68126738350132 1.7264284440206756 0.0842703622454159 1.0 0.3329409976574671 4 Q13126 1
Chondroitin sulfate dermatan sulfate metabolism 0.6848080477037772 1.7234688225467858 0.0848037785258628 1.0 0.3340828969592349 5 Q8NCH0,O94766,P06865 3
Regulation of beta cell development 0.6801416927564201 1.721137593401037 0.0852258589440673 1.0 0.3347808884383333 4 P31751 1
E2f enabled inhibition of pre replication complex formation 0.6836348030472196 1.69914717855707 0.0892914559775113 1.0 0.3487469152035942 6 Q9Y619,P14635,P06493 3
Intracellular signaling by second messengers 0.419849385028178 1.6767079470385744 0.0935996058379602 1.0 0.3604532556785854 82 P28072,P67870,P49720,P30153,P60900,P28074,O00459,P49721,P28070,P25788,Q8TBX8,P31751,P20618,P42345,Q9HCE1 15
Mitotic metaphase and anaphase 0.319655745007774 1.6766696426388417 0.0936071000482061 1.0 0.3604532556785854 134 P28072,Q96EE3,P30153,Q14739,P50748,P60900,P28074,P49720,P06493,Q53HL2,P49721,P30260,P28070,Q7Z460,Q7Z5K2,P63151,P62826,P30154,Q2NKX8,Q96IY1,P50402,P14635,Q6IPU0,Q6P1K2,Q16763,P20618,Q9H1A4,Q86Y07,O60566,P25788,Q9BZD4,Q92973 32
Metabolism of fat soluble vitamins 0.6742509096165813 1.6736837115799073 0.0941927766471588 1.0 0.3616896788670398 5 P01130 1
Metabolism of carbohydrates 0.311578068262913 1.668438873765335 0.0952286367505066 1.0 0.363624431390901 95 P30153,P17858,P06865,P15586,O43505,P13807,O43252,P16278,Q99653,Q8NCH0,P54802,Q00796,O94766,Q9UHD1,Q7LGA3 15
Downregulation of tgf beta receptor signaling 0.6790320214708728 1.660899374481314 0.0967336579252531 1.0 0.3673191955106139 7 O14980,P62140,Q96PU5,P62136 4
Cell cycle checkpoints 0.3171297773176685 1.6591170799025294 0.0970922021901314 1.0 0.3676593916728802 138 P28072,Q9NXR7,Q96EE3,P30153,P60900,P50748,P49720,P28074,Q53HL2,P06493,Q13472,O43264,P43034,P62195,P40938,Q99460,P49721,P30260,P28070,P33993,Q7Z460,Q12769,P24941,P48556,P57740,P42771,P30154,O43242,Q2NKX8,P51665,Q9UBD5,Q9UL46,Q96IY1,P33992,P14635,Q9Y619,Q6IPU0,Q6P1K2,Q16763,P20618,P25205,Q9UJX3,O14980,O43684,P16104,Q9H1A4,Q8WXE1,O60566,Q9UQ84,O00231,Q99436,P25788,P27694,Q9BZD4,P33991 55
Unwinding of dna 0.6813437703848487 1.6562439549538264 0.0976724251529517 1.0 0.3679402400641164 8 P33992,Q9BRX5,Q9BRT9,P33993,Q14566,P25205,P33991 7
Heme biosynthesis 0.6662628635693584 1.6557562876400844 0.097771183300084 1.0 0.3679402400641164 4 P50336 1
Regulation of tp53 expression and degradation 0.680749253969185 1.6386020483298491 0.1012961654772504 1.0 0.3722361779768852 9 P30153,P42771,P30154,P31751,P42345 5
Activated ntrk2 signals through cdk5 0.6513671875000073 1.627929947616 0.1035397404801283 1.0 0.3764330458413339 2 Q00535 1
Dscam interactions 0.6513671875000032 1.627929947615979 0.1035397404801328 1.0 0.3764330458413339 2 Q16512 1
Dna damage reversal 0.6595240020364163 1.6239165316438882 0.1043936238207103 1.0 0.3775293221241034 4 Q8N3C0,Q9H1I8 2
Mitotic g2 g2 m phases 0.4523205452364473 1.6100036001537852 0.1073970703506299 1.0 0.3860589519465333 78 P28072,P49720,P30153,P60900,O75935,P28074,P06493,P43034,P62195,Q99460,P49721,P61163,P28070,Q9BSJ2,Q7Z460,Q9BVA1,P07437,P24941,P48556,Q9H6D7,P63151,O75832,P30154,O43242,P51665,Q9UL46,Q7Z4H7,P41208,P14635,Q96CW5,P62140,P20618,Q9BUF5,O14980,O00231,Q99436,P25788,O94927,Q5TKA1 39
Signaling by ntrk2 trkb 0.6515792901335006 1.6072118200946135 0.1080079099882351 1.0 0.3860589519465333 3 Q00535,P62993 2
Dap12 signaling 0.6515792901335007 1.6072118200946135 0.1080079099882351 1.0 0.3860589519465333 3 O00459,P62993 2
Fanconi anemia pathway 0.6561096901937195 1.5877940151543426 0.1123329252503813 1.0 0.3980558807754968 5 Q9BXW9,Q8WXE1,Q9NVI1 3
Dap12 interactions 0.651791530944605 1.5873133048745924 0.1124417033593572 1.0 0.3980558807754968 4 O00459,P62993,P10321 3
Binding and uptake of ligands by scavenger receptors 0.6691181132660629 1.5829567975800285 0.1134313116653453 1.0 0.3986133754409437 9 P04114,Q5KU26,Q8WTV0 3
P75ntr regulates axonogenesis 0.6450667535004814 1.576401231858512 0.1149333646782335 1.0 0.4011413917055503 3 P61586,P52565 2
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.6520427076316143 1.568486445171184 0.1167676508908845 1.0 0.4051304029640589 5 Q8NB78,Q9BZK7 2
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.6542781222049067 1.5599134778703871 0.1187803290110927 1.0 0.4110701512864904 6 Q96J02,P61088,Q9Y2Z0,P09601 4
Synthesis of pips at the late endosome membrane 0.640626045564809 1.5553647240603548 0.1198592305177776 1.0 0.4137564851459649 3 Q13614 1
Plasma lipoprotein clearance 0.6743889661335278 1.5359060748595992 0.1245614180199099 1.0 0.4227675880770795 15 P04114,Q8WTV0,O15118,P01130 4
Peptide ligand binding receptors 0.6490643222131572 1.5350871340398915 0.1247624261983908 1.0 0.4227675880770795 6 P42892,P07602 2
Class a 1 rhodopsin like receptors 0.6490643222131572 1.5350871340398915 0.1247624261983908 1.0 0.4227675880770795 6 P42892,P07602 2
Cholesterol biosynthesis 0.6771313135556787 1.5319374810149826 0.1255378632301171 1.0 0.4227675880770795 17 Q15392,Q14739,P37268,O76062 4
Programmed cell death 0.3015358528534237 1.52186490913466 0.1280429333355028 1.0 0.4258751578336556 94 P28072,Q16625,P60900,P28074,Q07021,P49721,P28070,P25788,P31751,P41440,P20618,Q14126,P26583 13
Eukaryotic translation elongation 0.4609542298789064 1.518263314204097 0.128948032006525 1.0 0.4268086192564642 76 Q05639,P62701,P15880,P62081,P61254,P62829,P62280,P62273,P83881,P62244,P62249,P61353,P62913,P46777,P18621,P62753,P13639,P24534,P62263,P23396,P61513,P61927,P18124,P62841,P61313,P84098,P39023,P62847,Q02878,P60866,P63220,P62241,P62750,P46783,P18077,P08865,P27635,P46776,P25398,P32969,P62851,P08708,P46779,Q9Y3U8,P83731,Q02543,P62266,P35268,P26373,P26641 50
Interleukin 15 signaling 0.6263020833333377 1.509343511540071 0.1312110206905501 1.0 0.431166983855745 2 P62993 1
Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members 0.6263020833333329 1.5093435115400484 0.1312110206905559 1.0 0.431166983855745 2 Q13794 1
Dcc mediated attractive signaling 0.6246744791666687 1.5016199864930364 0.1331952786474883 1.0 0.4355931720361641 2 P63000 1
Vitamin b5 pantothenate metabolism 0.6370464381809806 1.4971542217824656 0.1343531338240695 1.0 0.4383311072494107 5 P49327,Q9NRN7,Q9Y289 3
Negative regulation of fgfr2 signaling 0.6261935867601178 1.4868585104071392 0.1370521842081931 1.0 0.438759568647775 3 P30153 1
Negative regulation of fgfr1 signaling 0.6261935867601178 1.4868585104071392 0.1370521842081931 1.0 0.438759568647775 3 P30153 1
Negative regulation of fgfr3 signaling 0.6261935867601178 1.4868585104071392 0.1370521842081931 1.0 0.438759568647775 3 P30153 1
Signaling by fgfr3 0.6261935867601178 1.4868585104071392 0.1370521842081931 1.0 0.438759568647775 3 P30153 1
Signaling by fgfr4 0.6261935867601178 1.4868585104071392 0.1370521842081931 1.0 0.438759568647775 3 P30153 1
Signaling by fgfr1 0.6261935867601178 1.4868585104071392 0.1370521842081931 1.0 0.438759568647775 3 P30153 1
Spry regulation of fgf signaling 0.6261935867601178 1.4868585104071392 0.1370521842081931 1.0 0.438759568647775 3 P30153 1
Negative regulation of fgfr4 signaling 0.6261935867601178 1.4868585104071392 0.1370521842081931 1.0 0.438759568647775 3 P30153 1
Tgf beta receptor signaling activates smads 0.6427494748750847 1.4717655930006264 0.1410841878791058 1.0 0.4484057465947177 8 O14980,P62140,Q96PU5,P62136 4
Negative regulation of mapk pathway 0.6410584656643985 1.4636556216071466 0.1432880667648219 1.0 0.4484057465947177 8 Q99956,P30153,P30086 3
Cd28 dependent vav1 pathway 0.6250814332247507 1.4604041384112378 0.1441790360928041 1.0 0.4484057465947177 4 P63000,Q16512,P62993 3
Cdc6 association with the orc origin complex 0.6250723646815225 1.460360949821066 0.1441908991176115 1.0 0.4484057465947177 4 Q9Y619 1
Interleukin 37 signaling 0.6139322916666706 1.4505880781973752 0.1468945969756769 1.0 0.4493857703956599 2 P40763 1
Recycling of eif2 gdp 0.6259617941897713 1.444312956342268 0.1486509628814907 1.0 0.4515685916866617 5 Q14232,P05198 2
Response of eif2ak4 gcn2 to amino acid deficiency 0.4608881884863834 1.4369191130164924 0.1507409783938667 1.0 0.4558914103195039 75 P62701,P15880,P62081,P61254,P62829,P62280,P62273,P83881,P62244,P05198,P62249,P61353,P62913,P46777,P18621,P62753,P23396,P62263,P61513,P61927,P18124,P62841,P08243,P61313,P84098,P39023,P62847,Q02878,P60866,P63220,P62241,P62750,P46783,P18077,Q92616,P08865,P27635,P46776,P25398,P32969,P62851,P08708,P46779,Q9Y3U8,P83731,Q02543,P62266,P35268,P26373 49
Erks are inactivated 0.6178140619172456 1.4054269204844487 0.1598943662639151 1.0 0.4741336197023255 5 P30153 1
Amino acid transport across the plasma membrane 0.6083725674483512 1.4020418283450298 0.1609027564051695 1.0 0.4750888240938065 3 P30825 1
Beta catenin phosphorylation cascade 0.6155247530038084 1.3944958489222794 0.1631679221563948 1.0 0.4776243031858496 5 P48729,P30154,P30153 3
Disassembly of the destruction complex and recruitment of axin to the membrane 0.6155247530038084 1.3944958489222794 0.1631679221563948 1.0 0.4776243031858496 5 P48729,P30154,P30153 3
Signaling by ctnnb1 phospho site mutants 0.6155247530038084 1.3944958489222794 0.1631679221563948 1.0 0.4776243031858496 5 P48729,P30154,P30153 3
Gpcr ligand binding 0.6262850088362782 1.3927495530883514 0.1636955381888925 1.0 0.4780639627344208 8 P42892,P07602 2
Ptk6 regulates rho gtpases ras gtpase and map kinases 0.6106646287510107 1.3916858282641926 0.164017555612614 1.0 0.4780639627344208 4 P61586,Q96JJ3 2
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.6158838663721748 1.376642473273394 0.1686228124892355 1.0 0.4863024993096728 6 Q14181,P30154,P30153,P49642 4
Rna polymerase iii transcription initiation from type 3 promoter 0.6062238566866917 1.3705007307893116 0.1705306474335719 1.0 0.4887115200035489 4 O15160 1
Rna polymerase iii chain elongation 0.6062238566866917 1.3705007307893116 0.1705306474335719 1.0 0.4887115200035489 4 O15160 1
Metabolism of lipids 0.275476048976991 1.3608305275638186 0.1735672521990749 1.0 0.4943050703252823 202 P67870,Q9UMR5,Q9NPH0,Q14739,P37268,P23786,Q15392,Q8NCC3,O76062,P09960,Q99538,Q8IV08,Q96G23,P06280,Q8IY17,P06865,O43772,Q13614,Q15185,P50897,P16278,Q9UBM7,Q8TBX8,P07602 24
Glycogen metabolism 0.6150580846334592 1.3388320042069957 0.1806253693971045 1.0 0.498817939324933 8 P06737,P13807,P35573,P46976 4
Rho gtpase effectors 0.2942145270057163 1.331696794818402 0.1829598429278311 1.0 0.499021603314173 102 Q96EE3,Q9UQB8,P30153,P50748,Q53HL2,P07737,Q7Z460,Q96F07,P30154,Q2NKX8,Q96IY1,Q07866,Q13526,Q6IPU0,Q7L576,O15145,Q6P1K2,P61586,P62140,Q92747,O60566,Q99570,Q9BZD4 23
Ticam1 rip1 mediated ikk complex recruitment 0.5885416666666731 1.3296928023329466 0.1836195072911695 1.0 0.499021603314173 2 P61088 1
Ikk complex recruitment mediated by rip1 0.5885416666666731 1.3296928023329466 0.1836195072911695 1.0 0.499021603314173 2 P61088 1
Caspase activation via death receptors in the presence of ligand 0.588541666666673 1.329692802332946 0.1836195072911697 1.0 0.499021603314173 2 P49327 1
Caspase activation via extrinsic apoptotic signalling pathway 0.588541666666673 1.329692802332946 0.1836195072911697 1.0 0.499021603314173 2 P49327 1
Regulation by c flip 0.588541666666673 1.329692802332946 0.1836195072911697 1.0 0.499021603314173 2 P49327 1
Regulation of tnfr1 signaling 0.5885416666666728 1.329692802332946 0.1836195072911697 1.0 0.499021603314173 2 P63244 1
Regulation of innate immune responses to cytosolic dna 0.5852864583333393 1.3141793731619174 0.1887858481826523 1.0 0.5064257115926969 2 Q9UJV9 1
Tnfr1 induced nfkappab signaling pathway 0.5887333116248704 1.3084149788540695 0.1907325948160323 1.0 0.5064257115926969 3 P63244,Q15750 2
Signaling by alk 0.5963580551805359 1.3029391069873066 0.1925955513605344 1.0 0.5064257115926969 5 Q92769,O00459 2
Pi5p regulates tp53 acetylation 0.586769630713386 1.2990511614497064 0.1939263720246415 1.0 0.506878299345478 3 Q8TBX8 1
Signaling by wnt 0.3853950555557858 1.2945888605258933 0.1954620971712874 1.0 0.5099173412846374 82 P28072,P67870,P49720,P30153,P60900,P61586,O75436,P28074,P07737,P49721,P28070,P25788,P31751,P20618,Q9HCE1 15
Tnf signaling 0.5889250814332206 1.2879493256810637 0.197763603525876 1.0 0.5139597833077426 4 P63244,O95429,Q15750 3
Cd28 co stimulation 0.6074912501355264 1.2866873028777714 0.1982033004065451 1.0 0.5141250695554974 9 P42345,P31751 2
Signaling by erbb2 ecd mutants 0.5879167402702251 1.2831380068755045 0.1994437302882503 1.0 0.5144143005736571 4 Q16543,P62993 2
Constitutive signaling by overexpressed erbb2 0.5879167402702251 1.2831380068755045 0.1994437302882503 1.0 0.5144143005736571 4 Q16543,P62993 2
Signaling by erbb2 in cancer 0.5879167402702251 1.2831380068755045 0.1994437302882503 1.0 0.5144143005736571 4 Q16543,P62993 2
Class b 2 secretin family receptors 0.5777994791666727 1.2784988121832817 0.2010736033182714 1.0 0.5166684506317237 2 Q9Y3E5 1
Membrane trafficking 0.2653955080891911 1.2770587900692725 0.2015814924195227 1.0 0.5170016888132976 220 Q9H3P7,Q9UNS2,O00743,P24390,Q9UIQ6,P53634,Q8TAG9,P31751,O14976,O60499,Q9UP83,Q9BVA1,O75976,Q5VZ89,Q96KP1,P11717,Q10471,P04114,O60476,P02786,Q92905,Q14108,O15027,O94979,O60749,Q9UJW0,Q07866,Q15102,O43731,Q9BXS5,Q8NC96,O15145,P01130,Q92734,Q92538,Q9NVG8,O00461,Q92747,Q9BUF5,Q9H2M9,Q7Z392,P50570,P02792,P15586,Q86Y91,O00471,Q13637,P47755,Q12981,Q9Y3B3 50
Glycogen breakdown glycogenolysis 0.5941533261495802 1.2727103039654082 0.2031208598896383 1.0 0.5179111228557322 6 P06737,P35573,P46976 3
Generation of second messenger molecules 0.5764973958333404 1.2722941938998489 0.2032686107487635 1.0 0.5179111228557322 2 Q16512 1
Uptake and function of diphtheria toxin 0.5837133550488529 1.2630845091675016 0.2065588104596494 1.0 0.523442342084066 4 P13639,Q16881,P07900 3
Signaling by insulin receptor 0.6185063069787384 1.2621157826796074 0.2069071269133067 1.0 0.523442342084066 15 O00459,Q9Y487,P31751,Q99570 4
Negative regulation of the pi3k akt network 0.6106976798876076 1.2595122987959737 0.2078453507698268 1.0 0.523442342084066 12 P31751,P30153,Q8TBX8,O00459 4
G beta gamma signalling through cdc42 0.5779876261803886 1.2571821286972258 0.2086876930766759 1.0 0.523442342084066 3 P60953,Q16512 2
Sema3a pak dependent axon repulsion 0.5839035516454932 1.2434675833697992 0.2136955792847983 1.0 0.5320980999678019 5 P63000,Q16512,P07900,P23528 4
Uptake and actions of bacterial toxins 0.5839035516454917 1.2434675833697912 0.2136955792848012 1.0 0.5320980999678019 5 P13639,Q8WUM4,Q16881,P07900 4
Ldl clearance 0.6070054967670306 1.228952576582394 0.2190895870720171 1.0 0.5386609092220277 13 P04114,O15118,P01130 3
Regulation of pten stability and activity 0.6083246426531808 1.2155730597086902 0.2241476018959542 1.0 0.5483418278693097 41 P28072,P67870,P60900,P49721,P28070,P25788,P31751,P20618 8
Costimulation by the cd28 family 0.6042031069675973 1.2153556079820111 0.2242304914257089 1.0 0.5483418278693097 13 P30153,O00459,P41240,P30154,Q16512,P31751,P42345 7
Cyclin a b1 b2 associated events during g2 m transition 0.591050169413218 1.207678527914793 0.227170940359888 1.0 0.5545404919142267 9 O14980,P30153,P14635,P63151,P06493,P30154 6
Mismatch repair 0.5926546708528 1.2002288819892848 0.2300504612693448 1.0 0.5569862145067194 10 P52701,P49005,Q9UQ84,P28340,P27694 5
Glycogen storage diseases 0.5693811074918332 1.194772190097092 0.2321760485774544 1.0 0.55779377575638 4 P13807,O43826,P46976 3
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.587321692255003 1.1897926883782517 0.2341278840639464 1.0 0.5598190657282887 9 P46379,P50402,P09601 3
Transferrin endocytosis and recycling 0.5912376544920575 1.179031482915562 0.2383856397067891 1.0 0.5667359469203145 11 P02786,Q9Y487 2
Assembly and cell surface presentation of nmda receptors 0.5695274470358123 1.1749309864365398 0.2400223275022641 1.0 0.569636322388186 5 Q9BUF5,Q9BVA1,O14936 3
Neutrophil degranulation 0.2774588069565935 1.163155231667614 0.2447665264975502 1.0 0.5762544612200338 165 P67870,P17858,P09110,P53634,Q5T4S7,Q93050,O15126,Q9Y376,P07437,P42785,O00571,P10321,Q14019,Q8N1F8,P11717,P04439,P09960,O43242,O00754,P06756,Q8WVQ1,P06280,O00584,P61916,P78371,P27105,Q7L576,O75874,P20618,P61586,P04066,P02792,P15586,Q9BTY2,Q9NQX7,Q99536,P16278,P30519,P07686,O43681,P07602 41
Iron uptake and transport 0.604118203074284 1.1630092373598546 0.2448257546003405 1.0 0.5762544612200338 18 P02792,Q9Y487,P02786,P30519,P09601 5
Pi3k akt signaling in cancer 0.5763197359907981 1.153142572084992 0.248851870288854 1.0 0.5823055605306328 8 P42345,P31751 2
Visual phototransduction 0.568705662833749 1.151271934997407 0.2496203792764819 1.0 0.5823055605306328 6 P01130 1
Cross presentation of soluble exogenous antigens endosomes 0.6046279599558758 1.1462821432219903 0.2516784290381231 1.0 0.5851095450597181 36 P28072,P60900,P49721,P28070,P25788,Q9UBG0,P20618 7
Developmental biology 0.2530506668384693 1.1424122333167075 0.2532827086619766 1.0 0.5878394953156572 245 P49721,P28070,Q9UBL3,Q7Z460,P31751,P61353,P61513,O43242,Q9NVC6,P84098,P62847,O94813,Q86X55,P46783,P27635,Q00535,Q92747,Q9BUF5,Q9NR77,Q92600,P46779,O00231,P28072,P67870,P62829,P62280,Q9BVA1,P48556,P18621,P51812,P62753,P62263,Q9UL46,P46939,O75448,P60866,P63220,Q9NPJ6,P20618,P62495,Q9BPU6,Q9BZK7,Q99436,Q16512,P25788,P60900,P28074,P07737,O00330,Q99460,P24941,P52298,P62993,Q15370,P62841,Q14126,P51665,P13591,P39023,P62241,Q96S59,Q15375,P61586,P46776,P16104,P19387,Q96CW1,P62266,P35268,Q9Y2X0,P11802,P49720,P15880,P62195,P62244,P62273,P83881,Q93074,P62913,P23396,O75832,O00459,P07900,Q96P70,P61927,P18124,P06756,O15145,Q15369,P50570,P08708,Q9Y3U8,P83731,Q13617 94
Dna replication initiation 0.5737944948860476 1.141086621532152 0.253833878031775 1.0 0.5881201885922652 8 Q9NR33,P49642,P56282,Q14181,Q07864,P49643 6
E2f mediated regulation of dna replication 0.5858209279322346 1.1393143750728951 0.2545720547897041 1.0 0.5881315272706203 12 P30153,P14635,Q9Y619,P06493,P30154,Q9UBD5 6
Signaling by egfr 0.5618743022697055 1.138527289004499 0.2549003705828792 1.0 0.5881315272706203 5 P42566,P62993,P41240 3
Mtor signalling 0.5882156937593639 1.1379784584741108 0.2551294774480452 1.0 0.5881315272706203 13 P06730,P23588,P31751,Q9Y376,P42345 5
Stat3 nuclear events downstream of alk signaling 0.5553412591966603 1.1280233105916158 0.2593100746563532 1.0 0.5957594488323276 4 Q92769 1
Interleukin 23 signaling 0.5436197916666743 1.115944867835552 0.2644457345588449 1.0 0.6055231476414422 2 P40763 1
Signaling by interleukins 0.2762058866099174 1.1015255803489776 0.2706679775688707 1.0 0.6143359442317525 97 P28072,P49720,P30153,P60900,Q13277,P28074,O00170,O00459,P49721,Q53EL6,P28070,P25788,Q9H3K6,Q13126,P20618,P09601 16
Processive synthesis on the lagging strand 0.574728358954717 1.0997517166807915 0.2714403147885724 1.0 0.6143359442317525 11 P49642,P49005,Q14181,P27694,P28340,P49643,Q9Y2S7,P12004 8
Rna polymerase iii transcription termination 0.5522971652003802 1.0930853538501757 0.2743563259093315 1.0 0.6151914471531941 5 P05455,O15160,O14802,P19388 4
Cyclin d associated events in g1 0.568761958096904 1.0857465202734684 0.2775911528849326 1.0 0.6155389409112688 10 P30153,P63151,P11802,P42771,P30154,Q13309 6
Vitamin d calciferol metabolism 0.5459900278529422 1.0837106812277597 0.2784930982339828 1.0 0.6160195231162695 4 Q99538 1
Nr1h2 and nr1h3 mediated signaling 0.5553856821221159 1.0703760123781274 0.2844500921159043 1.0 0.6222781647454553 7 Q8NB78,Q9BZK7 2
Cyclin a cdk2 associated events at s phase entry 0.5791140888538264 1.062123371338722 0.2881796813706323 1.0 0.6292997195425789 42 P28072,P49720,P60900,P28074,Q99460,P49721,P28070,P31751,P24941,Q13309,P48556,O43242,Q9UL46,P20618,Q99436,O00231,P25788,Q5TKA1,P11802 19
Rho gtpases activate wasps and waves 0.5785361213358866 1.0570185053797987 0.2905031419150872 1.0 0.6333617145102459 16 Q9UQB8,Q96F07 2
Telomere c strand synthesis initiation 0.5479928784148148 1.053024133026446 0.2923299316613539 1.0 0.6353027794760391 6 Q14181,Q9NYB0,P49642,P49643 4
Polo like kinase mediated events 0.5391645854690323 1.051463908857463 0.2930455769994688 1.0 0.6353027794760391 4 P14635 1
Coenzyme a biosynthesis 0.5299479166666763 1.0512946432911103 0.2931232865633062 1.0 0.6353027794760391 2 Q9NVE7 1
Signaling by cytosolic fgfr1 fusion mutants 0.5512953774695667 1.0510134406031684 0.293252416861288 1.0 0.6353027794760391 7 Q9UBW7 1
Gap junction trafficking and regulation 0.5541010298379175 1.0474430927956644 0.2948952655482486 1.0 0.6362907363077869 8 Q9BUF5,P50570,Q07157,Q96CW1,Q9BVA1 5
Oncogene induced senescence 0.5425470749347123 1.0469885747150247 0.2951048477096831 1.0 0.6362907363077869 5 Q9HCE1,P11802 2
Egfr downregulation 0.5328438990929784 1.021689154946165 0.3069280456377932 1.0 0.6576342294464942 4 P42566,P62993 2
G2 m dna replication checkpoint 0.5278089355188522 1.0192185187151377 0.308099236828028 1.0 0.658080713662366 3 P14635 1
Interferon alpha beta signaling 0.5443039876459181 1.0180076210343003 0.3086743343357747 1.0 0.6582805226786335 7 P04439,P10321 2
Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.5224609375000102 1.0160422973253498 0.309609245036236 1.0 0.6592458535273125 2 P63000 1
Ephrin signaling 0.5256203957593936 1.0089352526880515 0.3130056871108415 1.0 0.6607656511699167 3 Q16512 1
Nef mediated downregulation of mhc class i complex cell surface expression 0.5344143106332266 1.0086969663988652 0.3131199871053176 1.0 0.6607656511699167 5 P04439 1
Synthesis of pips at the plasma membrane 0.5444847153911493 1.0020279593071666 0.3163300894299188 1.0 0.6652665111549215 8 Q13614,Q8TBX8 2
Activation of the pre replicative complex 0.5742620003477887 0.993912414056353 0.3202655100912985 1.0 0.6704486252600385 21 P33992,Q9NR33,P49642,P56282,Q14181,Q9Y619,P27694,P33991,P33993,P49643,Q14566,Q9UBD5,P25205,P24941 14
Dna replication pre initiation 0.5034609217947899 0.988579350747802 0.3228689932624065 1.0 0.673834982885053 60 P28072,P49720,P60900,P28074,P62195,Q99460,P49721,P28070,P33993,P24941,P48556,Q9NR33,Q14181,O75832,O43242,Q14566,P51665,Q9UL46,Q9UBD5,P33992,P49642,Q9Y619,P49643,P20618,P25205,P16104,P56282,Q99436,O00231,P25788,P27694,P33991 32
Gap junction degradation 0.526397430406344 0.9711203236575512 0.3314883642910375 1.0 0.6876245735748837 5 Q96CW1,P50570,Q00610 3
Orc1 removal from chromatin 0.5440392059139902 0.9659226174333736 0.3340829038726576 1.0 0.6919565599907923 49 P28072,P49720,P60900,P28074,Q99460,P49721,P28070,P33993,P24941,Q13309,P48556,O43242,Q9UL46,Q9UBD5,P33992,Q9Y619,P20618,P25205,Q99436,O00231,P25788,P33991 22
Cellular response to hypoxia 0.5674472912174323 0.9593984305592744 0.3373580654471619 1.0 0.6976830188597132 38 P28072,P48556,P49720,Q15369,P60900,P28074,Q15370,Q13617,Q99460,P49721,Q99436,P28070,O43242,O00231,P25788,P20618,Q9UL46 17
Mitotic prometaphase 0.3102087231552178 0.9550403318790818 0.3395573013627162 1.0 0.698007264605764 87 P67870,Q96EE3,P30153,P50748,Q53HL2,O75935,P06493,O43264,P43034,Q9BSJ2,Q7Z460,Q12769,Q9BVA1,P07437,Q7Z5K2,Q9H6D7,P57740,P30154,Q2NKX8,Q9NTJ3,Q7Z4H7,Q96IY1,P41208,P14635,Q96CW5,Q6IPU0,Q6P1K2,Q9BUF5,O14980,O43684,O60566,O94927,Q9BZD4,Q15021,Q8TD19 35
Energy dependent regulation of mtor by lkb1 ampk 0.529969830052647 0.9507580655246268 0.3417272044951942 1.0 0.701413045863259 7 Q9Y376 1
Mtorc1 mediated signalling 0.532758976952858 0.9470132377464476 0.3436320334708389 1.0 0.7027159398746082 8 P42345,P06730,P23588 3
Diseases of signal transduction by growth factor receptors and second messengers 0.2757564192967834 0.9462432412659092 0.3440245356452003 1.0 0.7027159398746082 134 P28072,P49589,P49720,P30153,P60900,P28074,P49721,P28070,P31751,P42345,Q99956,Q9UBW7,O00459,Q92614,P30154,Q92734,P20618,P51114,Q6WCQ1,P35269,O43252,Q9BZK7,P25788,P30086 24
Vegfr2 mediated vascular permeability 0.5315045041319941 0.9251418352965038 0.3548921341339963 1.0 0.7180136798040482 9 P31751 1
Deubiquitination 0.3425159201215023 0.9248047454477047 0.355067481746552 1.0 0.7180136798040482 83 P28072,Q9NXR7,P49720,P61586,P60900,P85037,P28074,P06493,O94966,P45974,Q9NZL9,Q96K76,P49721,P28070,Q8NB78,P25788,P20618,Q9HBM6 18
Regulation of hmox1 expression and activity 0.5466771475341556 0.9173761043706796 0.3589455899511349 1.0 0.7237147809191762 45 P28072,P67870,P60900,P49721,P28070,P25788,P20618,P09601 8
Cargo recognition for clathrin mediated endocytosis 0.5634920944583572 0.9107480590460824 0.3624281356170167 1.0 0.7276014629550875 30 P11717,P04114,Q8NC96,P01130,P02786,Q92905,Q14108 7
Regulation of runx3 expression and activity 0.5601888451389284 0.9087112469049652 0.3635025658513364 1.0 0.7286041165964471 36 P28072,P48556,P49720,P60900,P28074,P42771,Q99460,P49721,Q99436,P28070,O43242,O00231,P25788,P20618,Q9UL46 15
Cdt1 association with the cdc6 orc origin complex 0.554868307701466 0.8994711598109189 0.368401750813681 1.0 0.7369491654331638 39 P28072,P60900,Q9Y619,P49721,P28070,P25788,P20618 7
Metabolism of polyamines 0.5578715820924084 0.8966095816732266 0.3699272834161833 1.0 0.7380439572074398 36 P28072,P48556,P49720,P60900,P28074,Q99460,P49721,Q99436,P28070,O43242,O00231,P25788,P20618,Q9UL46,P19623 15
Rora activates gene expression 0.5054439625386304 0.893910996630335 0.3713695136254125 1.0 0.7389550584074802 4 Q9BZK7 1
Uch proteinases 0.541675103901699 0.8766373032092925 0.3806836709044101 1.0 0.7535042515753215 44 P28072,P60900,P28074,P49721,P28070,Q8NB78,P25788,P20618 8
Scf skp2 mediated degradation of p27 p21 0.5485586305456533 0.8736794452624921 0.3822928478136305 1.0 0.7535042515753215 40 P28072,P48556,P49720,P60900,P28074,P11802,Q99460,P49721,Q99436,P28070,O43242,P24941,O00231,P25788,P20618,Q9UL46,Q13309 17
Degradation of axin 0.5542378748045507 0.8733903150562966 0.3824503680886433 1.0 0.7535042515753215 35 P28072,P48556,P49720,P60900,P28074,Q99460,P49721,Q99436,P28070,O43242,O00231,P25788,P20618,Q9UL46 14
Flt3 signaling in disease 0.5034026321574565 0.8645327975275576 0.3872952714075661 1.0 0.7560351724061805 5 Q9UBW7 1
Signaling by flt3 fusion proteins 0.5034026321574565 0.8645327975275576 0.3872952714075661 1.0 0.7560351724061805 5 Q9UBW7 1
Regulation of ras by gaps 0.5511650413175664 0.8617914569412757 0.3888022869067629 1.0 0.7560351724061805 36 P28072,P60900,P49721,P28070,P25788,P20618 6
Degradation of dvl 0.5511650413175664 0.8617914569412757 0.3888022869067629 1.0 0.7560351724061805 36 P28072,P60900,P49721,P28070,P25788,P20618 6
Antigen processing cross presentation 0.5246043817224963 0.8520781234887999 0.3941707330615633 1.0 0.7642998469434852 49 P28072,P60900,P28074,Q9UIQ6,P49721,P28070,P25788,Q9UBG0,P20618,P10321 10
Asymmetric localization of pcp proteins 0.5475407936078465 0.8431106146110942 0.3991665828080277 1.0 0.7719781008062471 36 P28072,P60900,P49721,P28070,P25788,P20618 6
Cell cycle 0.2360173944418868 0.8429434505974804 0.3992600711558278 1.0 0.7719781008062471 289 P28072,P67870,Q96EE3,Q9NXR7,Q14739,P50748,P30153,P60900,P28074,P06493,Q13472,P49005,P11802,Q53HL2,P40938,O00743,P49721,P30260,P28070,Q5TKA1,P33993,P31751,Q7Z460,P49720,Q9BVA1,P04818,P07437,Q13309,P48556,Q7Z5K2,Q9H6D7,Q9NR33,P63151,Q14181,P42771,P62826,P31350,P30154,O43242,Q2NKX8,P41440,Q9NTJ3,Q9UBD5,Q7Z4H7,Q9UL46,Q96IY1,P33992,P50402,P14635,Q96CW5,Q9Y619,Q6IPU0,Q6P1K2,Q16763,P28340,P62140,P20618,Q9BRT9,Q9BUF5,Q9BRX5,P00374,Q9H1A4,Q86Y07,Q8WXE1,Q9Y6X3,O60566,Q9UQ84,O00231,P25788,O94927,P56282,Q9BZD4,Q92973,Q8TD19 74
Diseases of glycosylation 0.5421098666928965 0.8391724640617797 0.4013725369287773 1.0 0.7727735698953226 21 P16278,P06865,Q8NCH0,O43505 4
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.5219449384257807 0.8367705357407071 0.4027215622404083 1.0 0.7727735698953226 49 Q04637,P62701,P15880,P62081,O15371,P62280,P23588,P62273,P62244,P05198,P62249,P06730,P62753,P23396,Q14240,P62263,P62841,P60228,P62847,P62241,P60866,P63220,Q13347,P46783,Q9Y262,P08865,P25398,P62851,Q14152,P08708,Q7L2H7,P11940,P62266,O75822,O15372 35
Dna strand elongation 0.5448488086666164 0.829778609460998 0.4066639669237442 1.0 0.7785849338722105 25 P33992,P49642,Q9BRX5,P49005,Q14181,P27694,P40938,Q9BRT9,P49643,P33993,P41440,P28340,P49736,Q14566,Q9Y2S7,P25205,P33991 17
Pten regulation 0.4491078502140216 0.8273477990386756 0.4080399587335765 1.0 0.7801267462780408 66 P28072,P67870,P60900,P28074,P49721,P28070,P25788,P31751,P20618 9
Formation of tubulin folding intermediates by cct tric 0.5130002042485637 0.8244809167066219 0.4096663545631192 1.0 0.7821423277762346 10 Q9BUF5,P50990,P78371,P17987,Q9BVA1,Q99832 6
M phase 0.2529651682755065 0.8177209397594956 0.413516550885072 1.0 0.7883920851602418 184 P28072,P67870,Q96EE3,P30153,Q14739,P50748,P60900,P28074,P49720,P06493,Q53HL2,P49721,P30260,P28070,Q7Z460,P07437,Q7Z5K2,Q9H6D7,P63151,P62826,P30154,O43242,Q2NKX8,Q96IY1,P50402,P14635,Q96CW5,Q6IPU0,Q6P1K2,Q16763,P20618,Q9H1A4,Q86Y07,Q9Y6X3,O60566,P25788,O94927,Q9BZD4,Q92973 39
Interleukin 1 signaling 0.5369459650329736 0.8121610993796596 0.416699197696563 1.0 0.7933534864222864 40 P28072,P49720,P60900,P28074,P62195,Q99460,P49721,P61088,P28070,Q15750,P48556,O43242,P51665,Q9UL46,P20618,P09429,Q99436,O00231,P25788 19
Tcr signaling 0.5316087193244912 0.8105584065687026 0.4176193109709696 1.0 0.7939994410254736 43 P28072,P49720,P60900,P28074,P62195,P41240,Q99460,P49721,P61088,P28070,P48556,O00459,O43242,P51665,Q9UL46,P20618,Q99436,O00231,P25788,Q16512 20
Switching of origins to a post replicative state 0.4844564832868717 0.8036953386497536 0.4215729468424722 1.0 0.799292951919084 58 P28072,P49720,P60900,P28074,Q99460,P49721,P30260,P28070,P33993,P24941,Q13309,P48556,O43242,Q9UL46,Q9UBD5,P33992,Q9Y619,Q16763,P20618,P25205,Q9H1A4,Q99436,O00231,P25788,P33991 25
Met activates ras signaling 0.4841206109302426 0.7964932812732997 0.4257453791341938 1.0 0.8060857801612784 4 Q96S59,Q96P70 2
Plasma lipoprotein assembly remodeling and clearance 0.5284381855887508 0.7907738588115949 0.4290759670948256 1.0 0.8112681148252098 19 P04114,Q8WTV0,O15118,P01130 4
Signaling by erbb2 0.5070771972672377 0.7831913054844679 0.4335147798207437 1.0 0.816180655538758 11 P31751 1
Tnfr2 non canonical nf kb pathway 0.5336829367262605 0.7821004741544547 0.4341555281170461 1.0 0.816180655538758 38 P28072,P60900,P49721,P28070,P25788,P20618 6
Dectin 1 mediated noncanonical nf kb signaling 0.5336829367262605 0.7821004741544547 0.4341555281170461 1.0 0.816180655538758 38 P28072,P60900,P49721,P28070,P25788,P20618 6
Golgi associated vesicle biogenesis 0.5354678662051381 0.7810905224755319 0.4347492557212282 1.0 0.816180655538758 26 O60749,Q9H3P7,P50570,P02792,P11717,Q8NC96,P02786,O14976,O75976 9
Negative regulation of notch4 signaling 0.5333167850944038 0.7802282351265603 0.4352565456384452 1.0 0.816180655538758 38 P28072,P60900,P49721,P28070,P25788,P20618 6
Transcriptional regulation by runx2 0.5139590094334595 0.7760294681124423 0.43773158677526 1.0 0.8185760316303426 48 P28072,P60900,P14635,P28074,P49721,P28070,P25788,P31751,P20618,P11802 10
Parasite infection 0.5274233724631365 0.7635993967248859 0.4451060088999572 1.0 0.8297772309412375 22 Q9UQB8,Q96F07 2
Stabilization of p53 0.5293877683320065 0.7552658380877113 0.4500894919025193 1.0 0.8297772309412375 37 P28072,P48556,P49720,P60900,P28074,P42771,Q99460,P49721,Q99436,P28070,O43242,O00231,P25788,P20618,Q9UL46 15
Ion channel transport 0.5318625484141701 0.7547368171468527 0.4504069110577797 1.0 0.8297772309412375 32 P27105,Q96PU5,Q9C0H2,Q9HD20,P51790 5
Processing and activation of sumo 0.4703049220783439 0.7546730038001797 0.4504452084291159 1.0 0.8297772309412375 3 Q9UBT2 1
Sumo is transferred from e1 to e2 ube2i ubc9 0.4703049220783439 0.7546730038001797 0.4504452084291159 1.0 0.8297772309412375 3 Q9UBT2 1
Sumo is conjugated to e1 uba2 sae1 0.4703049220783439 0.7546730038001797 0.4504452084291159 1.0 0.8297772309412375 3 Q9UBT2 1
Regulation of runx2 expression and activity 0.5247098298069957 0.7486528287989846 0.4540664818925308 1.0 0.8306572961402728 40 P28072,P48556,P49720,P60900,P28074,Q99460,P49721,Q99436,P28070,O43242,O00231,P25788,P20618,Q9UL46,Q13309 15
G1 s dna damage checkpoints 0.5257425662612911 0.7474283461908116 0.4548050401112848 1.0 0.8306572961402728 39 P28072,P48556,P49720,P60900,P28074,P42771,Q99460,P49721,Q99436,P28070,O43242,O00231,P25788,P20618,Q9UL46,P24941 16
Interleukin 1 family signaling 0.5207999889810607 0.7439440878232261 0.4569103015750415 1.0 0.8306572961402728 42 P28072,P49720,P60900,P28074,P62195,Q99460,P49721,P61088,P28070,Q15750,P48556,O43242,P51665,Q9UL46,P20618,P09429,Q99436,O00231,P25788 19
Hedgehog on state 0.5237773198970002 0.7438740757783008 0.4569526603492941 1.0 0.8306572961402728 40 P28072,P48729,P49720,P48556,P60900,P28074,Q99460,P49721,Q96J02,P28070,O43242,Q99436,O00231,P25788,P20618,Q9UL46 16
The role of gtse1 in g2 m progression after g2 checkpoint 0.5167169865876606 0.7414006283953326 0.4584505635947067 1.0 0.8322734667117716 44 P28072,P49720,P60900,P28074,P06493,P62195,Q99460,P49721,P28070,Q9BVA1,P48556,O75832,O43242,P51665,Q9UL46,P14635,P20618,Q9BUF5,Q99436,O00231,P25788 21
Gap filling dna repair synthesis and ligation in gg ner 0.5141618292437726 0.734280057667647 0.4627780695298471 1.0 0.8379041338374849 18 P18887,Q9NR33,P49005,P40938,P28340,P56282,P41440 7
Clec7a dectin 1 signaling 0.5167389210860597 0.7229030570105891 0.4697394452776011 1.0 0.8450547515002896 42 P28072,P48556,P49720,P60900,P28074,P62195,Q99460,P49721,Q99436,P61088,P28070,O43242,Q15750,O00231,P25788,P20618,P51665,Q9UL46 18
Downstream signaling events of b cell receptor bcr 0.5217195213172766 0.7216038674416274 0.4705380607129268 1.0 0.8450547515002896 38 P28072,P60900,P49721,P28070,P25788,P20618 6
Bbsome mediated cargo targeting to cilium 0.4751207568816356 0.718287272626486 0.4725801760757755 1.0 0.8466803416718023 6 P17987,P50990,P78371 3
Fc epsilon receptor fceri signaling 0.5045942408459361 0.7112183171675099 0.4769489594938438 1.0 0.8505849392510528 47 P28072,P49720,P60900,P28074,P62195,Q99460,P49721,P61088,P28070,Q15750,P48556,O00232,P62993,O75832,O00459,P63000,Q13616,O43242,P51665,Q9UL46,P20618,Q99436,O00231,P25788,Q16512,Q15008 26
Trna modification in the nucleus and cytosol 0.4833594984323753 0.7064252505602527 0.4799237226584245 1.0 0.8514816400453954 9 Q9H974,Q5VV42 2
Degradation of beta catenin by the destruction complex 0.5058445636590592 0.7057613594124773 0.4803365555798233 1.0 0.8514816400453954 46 P28072,P48729,P49720,P30153,P60900,P48556,P28074,Q99460,P49721,Q99436,P28070,P30154,O43242,O00231,P25788,P20618,Q9UL46 17
Ripk1 mediated regulated necrosis 0.4895210475592438 0.7047911250669394 0.4809402323912839 1.0 0.8514816400453954 11 P49327,Q8WUM4,Q16543,P41440 4
Protein protein interactions at synapses 0.4862604576758929 0.7044846390094565 0.481131012907565 1.0 0.8514816400453954 10 P41440 1
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.4823783283998548 0.7021171364271376 0.4826061163190429 1.0 0.8523547299846663 9 Q16763,P45974 2
Synthesis of pg 0.4549523473611793 0.6869293334657047 0.4921272609818239 1.0 0.8638216400640476 3 Q8IV08 1
Fceri mediated nf kb activation 0.5109465745064431 0.6857111098763174 0.4928952995060613 1.0 0.8638306082369049 41 P28072,P48556,P49720,P60900,P28074,P62195,Q99460,P49721,Q99436,P61088,P28070,O43242,Q15750,O00231,P25788,P20618,P51665,Q9UL46 18
Heme signaling 0.4748628332906301 0.6845567850261783 0.4936236448153099 1.0 0.8639993885563749 8 P04114,P09601 2
Hedgehog off state 0.5047485025220411 0.678965231054616 0.4971598923764524 1.0 0.8683860877072346 44 P28072,P48729,P49720,P48556,P60900,Q9BUF5,P28074,Q99460,P49721,Q96J02,P28070,O43242,Q99436,O00231,P25788,P20618,Q9BVA1,Q9UL46 18
Epha mediated growth cone collapse 0.4698389091709675 0.6785857558808527 0.4974003706472309 1.0 0.8683860877072346 7 Q15375 1
Signaling by the b cell receptor bcr 0.5058641976496339 0.6675183988962703 0.5044410613016357 1.0 0.8768815166469649 42 P28072,P48556,P49720,P60900,P62993,P28074,Q99460,P49721,Q99436,P28070,O43242,O00231,P25788,Q13586,P20618,Q9UL46 16
G2 m checkpoints 0.3321254620534564 0.6669058098704174 0.5048322996350851 1.0 0.8768815166469649 81 P28072,Q9NXR7,P49720,P60900,P28074,P06493,Q13472,P40938,Q99460,P49721,P28070,P33993,P48556,O43242,Q9UL46,Q9UBD5,P33992,P14635,Q9Y619,P20618,P25205,Q8WXE1,Q9UQ84,O00231,Q99436,P25788,P27694,P33991 28
Role of lat2 ntal lab on calcium mobilization 0.4500637159517087 0.665714545481092 0.5055935745307221 1.0 0.8770893608927628 3 O00459 1
Nucleotide biosynthesis 0.4782747588032031 0.6557793829721887 0.5119660836471596 1.0 0.8847757728769495 11 P22102,P31939,P22234,Q06203,P12268,P27708,P30520,P11172 8
Glycosphingolipid metabolism 0.4871952436826766 0.6453403108664448 0.518706675081672 1.0 0.8902054933797008 15 P16278,P06280,P06865 3
Folding of actin by cct tric 0.4649807011526313 0.641946294090855 0.5209080543968057 1.0 0.8902054933797008 8 P50990,P50991,P78371,P40227,P17987,Q99832 6
Recognition of dna damage by pcna containing replication complex 0.4909653333538256 0.6409559870522659 0.5215512789402454 1.0 0.8902054933797008 17 Q9NR33,P49005,P40938,P28340,P56282,P41440 6
Platelet homeostasis 0.474039409627473 0.6375991210869448 0.5237346679568118 1.0 0.8902054933797008 11 P04114,P30153,Q13586 3
Degradation of gli1 by the proteasome 0.5033289883753377 0.6362127045644069 0.5246377936011655 1.0 0.8902054933797008 39 P28072,P48556,P49720,P60900,P28074,Q99460,P49721,Q96J02,P28070,O43242,Q99436,O00231,P25788,P20618,Q9UL46 15
Platelet aggregation plug formation 0.4516914517713511 0.6349232651366289 0.5254784627035183 1.0 0.8902054933797008 5 P41240 1
Integrin signaling 0.4516914517713511 0.6349232651366289 0.5254784627035183 1.0 0.8902054933797008 5 P41240 1
Termination of translesion dna synthesis 0.4891459528359541 0.6330898821037577 0.5266749491587084 1.0 0.8902054933797008 17 Q9NR33,P49005,P40938,P28340,P56282,P41440 6
Polymerase switching 0.4803408977853061 0.627140825497972 0.5305669280161844 1.0 0.8942081988544271 14 P49642,P49005,Q14181,P40938,P28340,P49643,P41440,Q9Y2S7 8
Condensation of prometaphase chromosomes 0.4662379274138655 0.6181017409097603 0.5365082747971179 1.0 0.8957231408306593 10 P67870,P14635,P06493,Q9BPX3,Q9NTJ3,Q15021 6
Cdc42 gtpase cycle 0.5009815823076875 0.6155190257353749 0.5382120085866535 1.0 0.8957231408306593 28 Q9Y4F1,Q9UQB8,Q14739,P02786 4
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.4718315382222633 0.6151723572224608 0.5384409010986424 1.0 0.8957231408306593 12 P67870,P19784,P50990,P50991,P78371,P17987,Q99832 7
Purine ribonucleoside monophosphate biosynthesis 0.4618015023789977 0.6135776877284247 0.5394944314335623 1.0 0.8957231408306593 9 P22102,P31939,P22234,Q06203,P12268,P30520 6
Synthesis of substrates in n glycan biosythesis 0.4630299529899798 0.6045940024814949 0.5454487926626836 1.0 0.9005409558420405 10 P16278 1
Tcf dependent signaling in response to wnt 0.4472062963533361 0.6022812609687056 0.5469869322729459 1.0 0.9012841990474252 59 P28072,P67870,P30153,P60900,P49721,P28070,P25788,P31751,P20618 9
G0 and early g1 0.4474573971445258 0.5994581786813443 0.5488673905712469 1.0 0.9025625967897598 6 P06493,Q5TKA1 2
Signaling by notch4 0.4926800331804171 0.5960176279998721 0.551163450478686 1.0 0.903405799525616 41 P28072,P60900,P49721,P28070,P25788,P20618 6
Polymerase switching on the c strand of the telomere 0.4774902298242555 0.5933569427486399 0.5529422979665526 1.0 0.9052360734374578 16 Q9NYB0,P49642,Q14181,P49005,P40938,P28340,P49643,P41440,Q9Y2S7 9
Beta catenin independent wnt signaling 0.470849337588388 0.5862233465354234 0.5577254346548044 1.0 0.908515041138911 51 P28072,P49720,P60900,P28074,P07737,P49721,P28070,P25788,P61586,P20618 10
Activation of gene expression by srebf srebp 0.4818938241599478 0.5840648017034467 0.559176714808735 1.0 0.908515041138911 19 Q9UBM7,P37268,O76062 3
Intra golgi traffic 0.4751714647729544 0.5836242849169008 0.5594731177952212 1.0 0.908515041138911 16 O00461,O60476 2
Sulfur amino acid metabolism 0.4567211985974324 0.5783264744047444 0.5630437236943586 1.0 0.91275082657798 10 Q9BV20,Q99707,Q16762,Q13126 4
Host interactions of hiv factors 0.2355206880046066 0.5775809390574809 0.5635470788197183 1.0 0.91275082657798 93 P28072,Q96EE3,P49720,P60900,P28074,Q99460,P49721,P28070,Q12769,P48556,P57740,P04439,Q15370,P62826,O43242,Q9UL46,Q9BXS5,P20618,O14980,Q15369,P50750,O00231,Q99436,P25788,P43487 25
Lagging strand synthesis 0.475845226541626 0.5766002277349982 0.564209545324355 1.0 0.91275082657798 17 P49642,P49005,Q14181,P27694,P40938,P28340,P49643,P41440,Q9Y2S7 9
Deadenylation of mrna 0.4564849825699134 0.5640682678217741 0.5727076726908931 1.0 0.9226001083569026 11 A5YKK6,P06730,Q04637,Q14240,Q92600,P23588,Q9HBH5,P11940 8
Pcna dependent long patch base excision repair 0.4747932959348816 0.5630001632847271 0.5734347727527478 1.0 0.9226001083569026 18 Q9NR33,P49005,P40938,P28340,P56282,P41440 6
Pcp ce pathway 0.4736248474583105 0.5626513144376629 0.5736723424311392 1.0 0.9226001083569026 48 P28072,P60900,P28074,P07737,P49721,P28070,P25788,P61586,P20618 9
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.4757173769071661 0.5582227523338873 0.576692286172368 1.0 0.9263670448855782 19 Q92890,Q9NR33,P56282,P49005,P27694,P40938,P41440,P28340,Q9Y2S7 9
Cytosolic trna aminoacylation 0.4810981136840329 0.5520175042847868 0.5809363605777202 1.0 0.930514654066694 23 P07814,P49589,Q13155,P56192,O43324,Q9P2J5,P49591,P26639,P41250,P47897,P26640,P23381,O43776,Q9NSD9 14
Apoptotic factor mediated response 0.4313882849346502 0.5504927794582882 0.5819814280147138 1.0 0.930514654066694 5 Q07021 1
Runx1 regulates transcription of genes involved in differentiation of hscs 0.4845118180163104 0.5478786900492781 0.5837752020168128 1.0 0.9321419226693356 39 P28072,P48556,P49720,P60900,P16104,P28074,P62195,Q99460,P49721,Q96J02,P28070,O43242,Q99436,O00231,P25788,P20618,P51665,Q9UL46 18
Trans golgi network vesicle budding 0.4861063150339313 0.5430411382804657 0.5871014783606832 1.0 0.9321419226693356 33 Q9H3P7,P15586,P11717,Q8NC96,P02786,O75976 6
Interleukin 2 family signaling 0.4250695691999961 0.5423507112708982 0.5875769272845504 1.0 0.9321419226693356 4 O00459,P62993 2
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.4250695691999961 0.5423507112708982 0.5875769272845504 1.0 0.9321419226693356 4 O00459,P62993 2
Rip mediated nfkb activation via zbp1 0.4197329859980326 0.5387861493333278 0.5900344217633751 1.0 0.9328174394359914 3 Q13546,Q9NZI8 2
Zbp1 dai mediated induction of type i ifns 0.4197329859980326 0.5387861493333278 0.5900344217633751 1.0 0.9328174394359914 3 Q13546,Q9NZI8 2
Neddylation 0.3799431914479994 0.5379306268559431 0.5906249433052111 1.0 0.9328174394359914 71 P28072,P49720,Q9UNS2,P60900,Q13098,P28074,Q99460,P49721,P28070,Q13564,Q13309,P48556,Q15370,O43242,Q92905,Q7L5N1,Q9UL46,Q9Y5A7,P20618,Q15369,Q99436,O00231,P25788,Q13617 24
Activation of ampk downstream of nmdars 0.4276367025754334 0.535353564045976 0.5924053937402516 1.0 0.9328174394359914 5 Q9BUF5,Q9BVA1,Q13131 3
Fcgamma receptor fcgr dependent phagocytosis 0.4829746957745848 0.5345166099183253 0.5929841608198738 1.0 0.9328174394359914 29 Q9UQB8,O00459,Q7L576,Q96F07,Q8IV08 5
Regulation of tp53 activity through acetylation 0.4579285161359235 0.5339945589004105 0.5933452985621392 1.0 0.9328174394359914 14 P31751 1
Transcriptional regulation by runx3 0.4793252750705509 0.5335207767668545 0.5936731326330011 1.0 0.9328174394359914 41 P28072,P49720,P60900,P28074,P49721,P28070,P25788,P20618 8
Nuclear events kinase and transcription factor activation 0.4431895889323159 0.5234167409140914 0.6006842767540079 1.0 0.940180013197884 10 Q00535,P30154,P30153,P50570 4
Gamma carboxylation hypusine formation and arylsulfatase activation 0.4393776927377763 0.5217039471594225 0.6018764760078477 1.0 0.940180013197884 9 P63241,P49366,Q9HA64,P38435,O43681 5
C type lectin receptors clrs 0.4709652242689456 0.5213591652945337 0.6021165922151033 1.0 0.940180013197884 45 P28072,P49720,P60900,P28074,P62195,Q99460,P49721,P61088,P28070,Q15750,P48556,O43242,P51665,Q9UL46,P20618,Q99436,O00231,P25788,Q16512 19
Rho gtpases activate rocks 0.4319701490518199 0.5208295591347966 0.6024855095547523 1.0 0.940180013197884 7 P61586,P62140,Q16512 3
Apoptosis 0.308067574995559 0.519811443230116 0.6031950027813284 1.0 0.9402138754869738 82 P28072,Q16625,P49720,P60900,P28074,Q07021,P49721,P28070,P25788,O00429,P31751,P20618,Q14126,P26583 14
Antigen activates b cell receptor bcr leading to generation of second messengers 0.4190624634683163 0.5182954783861444 0.6042521272185655 1.0 0.9407889042229828 4 Q13586 1
Rac1 gtpase cycle 0.4767757094370072 0.5171580499517526 0.605045833397273 1.0 0.940924089716012 40 Q9Y4F1,Q9UQB8,Q14739,P50402,P02786,Q96F07 6
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.4534850480712034 0.51619878213732 0.6057155807974328 1.0 0.940924089716012 14 Q9BUF5,P50990,P78371,P17987,Q99471,Q9BVA1,P61758,Q99832 8
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.4179428141790459 0.5138575372956486 0.6073515971742842 1.0 0.9413261148948372 4 P30153 1
Clathrin mediated endocytosis 0.4627004228031658 0.5094928486606964 0.6104068097234443 1.0 0.9449899307949584 48 Q9UNS2,P11717,P04114,Q8NC96,O15145,P01130,P02786,Q92905,O14976,Q14108 10
Methylation 0.4235400137438573 0.5025969004860456 0.6152477089004931 1.0 0.9514068077680704 6 Q99707 1
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.4562816344327368 0.4971459474593014 0.6190861351782435 1.0 0.9545487794454048 17 Q02818,Q9BTY2,P04114,O43852,Q06481 5
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.4625302480718113 0.496737218841919 0.6193743726174645 1.0 0.9545487794454048 20 Q9NR33,P56282,P49005,P27694,Q07864,P40938,Q9UGN5,P41440,P28340,P40937,P27695,Q9Y2S7 12
Dna damage bypass 0.4623391420945723 0.4887031077573142 0.6250519032693653 1.0 0.9585832975681532 21 Q92890,Q9NR33,P56282,P49005,P27694,P40938,P41440,P28340,Q9Y2S7 9
Infectious disease 0.2093937542014096 0.4882781575897731 0.6253528306579552 1.0 0.9585832975681532 322 Q96EE3,Q9UQB8,P19525,P49721,P28070,P61353,P07437,Q8WUM4,Q99720,P62826,P61513,O43242,Q96PU5,P84098,P83916,P62847,Q9BXS5,P46783,P27635,Q92747,Q9BUF5,P46779,O00231,P43487,P09601,P28072,P62829,P62280,Q96F07,Q9BVA1,P48556,P18621,P62753,P62263,Q9UL46,Q92804,P60866,P63220,Q7L576,P20618,O14980,Q15185,Q9H267,Q9BZK7,Q99436,P25788,P48729,P60900,P28074,Q13724,P04899,Q99460,Q12769,P52298,P57740,P62993,P04439,Q15370,P62841,Q02790,P51665,P39023,P62241,Q96JJ3,Q99873,Q9Y5B9,P46776,P19387,P35269,Q16881,Q99570,Q96CW1,Q9Y2Z0,P62266,P35268,P42566,P49720,P15880,P62195,P62244,P62273,P83881,Q96SB4,P18615,P62913,P23396,O75832,O95639,P07900,P61927,P18124,Q8IXH7,O15145,Q9HBM6,Q15369,P50750,P08708,O00410,Q9Y3U8,P83731 100
Apc c mediated degradation of cell cycle proteins 0.4358212944409554 0.4668674359914586 0.6405947246584072 1.0 0.9740745145806924 55 P28072,P49720,P60900,P28074,P06493,Q99460,P49721,P30260,P28070,P24941,Q13309,P48556,O43242,P51665,Q9UL46,P14635,Q16763,P20618,Q9UJX3,O43684,Q9H1A4,Q99436,O00231,P25788,O60566 25
Activation of atr in response to replication stress 0.4540468401503447 0.4635697162566167 0.6429560554874305 1.0 0.9744203181795208 20 P33992,Q9Y619,Q8WXE1,P40938,P33991,P33993,P27694,P49736,Q14566,Q9UBD5,P25205,P24941 12
Rho gtpase cycle 0.2391781921527541 0.4612642144318281 0.6446090559728177 1.0 0.9747436476370142 144 Q9Y4F1,Q9UQB8,Q14739,P50402,Q07021,P27105,P02786,Q13505,P41440,Q9BXS4,Q96F07,O75976 12
Transcriptional regulation by mecp2 0.440313365119805 0.4546925535047237 0.6493304388093122 1.0 0.978649073707089 15 Q9HCE1,Q14739,Q8WYQ5,Q9BZK7 4
Hedgehog ligand biogenesis 0.4617939907025367 0.4520770431302051 0.6512134812411905 1.0 0.9804061991813956 40 P28072,P60900,P49721,P28070,P25788,P20618 6
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.459749205406266 0.450480357379736 0.6523641144475536 1.0 0.981058024697256 26 Q9UJW0,Q9BUF5,P54652,O75935,P47756,Q15185,Q13451,P07900,P61163,O60884,P47755,Q02790,Q9BVA1 13
Miscellaneous transport and binding events 0.4085765690006973 0.4454350946899434 0.6560053550892206 1.0 0.9822191356847754 6 Q9UEY8 1
Metabolism of folate and pterines 0.4158654225793287 0.444787946345205 0.6564730059762354 1.0 0.9822191356847754 8 P41440 1
Regulation of mecp2 expression and activity 0.4257351908877114 0.4436705445481574 0.6572807944542436 1.0 0.9822191356847754 11 Q14739,Q9BZK7 2
Intraflagellar transport 0.4114870379970947 0.4286513644273829 0.6681769596051992 1.0 0.993854146828252 8 Q9BUF5,A0AVF1,Q9BVA1,Q92973 4
Dual incision in gg ner 0.4465475801065146 0.4280926309407457 0.668583681620871 1.0 0.993854146828252 21 Q9NR33,P56282,Q86WJ1,P49005,P27694,Q07864,P40938,Q9UGN5,P41440,P28340,P40937,Q9Y2S7 12
Signaling by vegf 0.4513016160626624 0.4278070142270075 0.6687916297916074 1.0 0.993854146828252 24 Q9UQB8,O00459,Q7L576,P31751,Q96F07,P61586,P42345 7
Cytosolic iron sulfur cluster assembly 0.3979840423620587 0.4217027583443314 0.673241990859635 1.0 0.9970983764952556 5 Q96T76,P28340 2
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.4425439194165311 0.4178811407093548 0.6760340219022536 1.0 0.9991726779411252 48 P28072,P49720,P60900,Q9H1A4,P28074,P49721,P28070,Q16763,P25788,P20618 10
Mitochondrial protein import 0.4557653836949947 0.4177138349713163 0.6761563558009991 1.0 0.9991726779411252 35 O60830,Q99595,Q9Y584 3
Regulation of bach1 activity 0.387685943610593 0.4157864753264548 0.6775662563653424 1.0 0.9991726779411252 3 Q13309 1
Rna polymerase iii transcription initiation from type 1 promoter 0.4072726054129483 0.4008027913451657 0.6885653236062539 1.0 1.0 9 Q9UKN8,O15160 2
Signaling by receptor tyrosine kinases 0.2280470950296768 0.3976888945706801 0.6908595245499243 1.0 1.0 106 Q9UQB8,P30153,Q01085,P35269,Q7L576,Q9Y487,O00459,Q99570,Q96P70,P30154,Q96S59,P31751,Q96F07,P61586,P42345 15
Rhoc gtpase cycle 0.4464958156193361 0.3965306781818038 0.6917135807622756 1.0 1.0 27 Q07021,P02786,Q14739,P41440 4
Platelet calcium homeostasis 0.3901030613611178 0.3935143486736279 0.6939396283525672 1.0 1.0 5 Q13586 1
Polb dependent long patch base excision repair 0.39002932551319 0.393255015215339 0.6941311398045551 1.0 1.0 5 P39748,P18858,Q9UGN5,P27695 4
Ros and rns production in phagocytes 0.4047440236417756 0.3919020294281697 0.6951306034276536 1.0 1.0 9 Q9Y487 1
Pi metabolism 0.4279726606684322 0.3913167379023431 0.6955631282590833 1.0 1.0 17 Q8IY17,Q9C0I1,Q99570,Q8TBX8,Q13614 5
Cytoprotection by hmox1 0.387598531279223 0.3871220042486127 0.6986658881797303 1.0 1.0 64 P28072,P67870,P60900,Q9BZK7,P49721,P28070,P25788,P30519,O43819,P20618,P09601 11
Fatty acyl coa biosynthesis 0.4256081405701976 0.3674111975422351 0.7133123203562928 1.0 1.0 19 Q9UMR5 1
Leishmania infection 0.4418555506764842 0.3653359206138598 0.7148606679656906 1.0 1.0 34 Q9UQB8,P09601,Q96F07,Q7L576 4
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.3731683490719564 0.3647729212005589 0.7152809201024792 1.0 1.0 3 P61009,Q15005 2
Synthesis secretion and deacylation of ghrelin 0.3731683490719564 0.3647729212005589 0.7152809201024792 1.0 1.0 3 P61009,Q15005 2
Metabolism of steroids 0.4314495285158097 0.3644317480002241 0.7155356315889883 1.0 1.0 47 Q15392,Q14739,P37268,O76062,Q9BZK7,Q9UBM7,Q99538 7
Signaling by rho gtpases miro gtpases and rhobtb3 0.2135308557241593 0.3641683009410554 0.7157323363293899 1.0 1.0 233 Q9UQB8,Q14739,P50748,P30153,Q53HL2,P07737,Q99707,Q96F07,O75976,Q9Y4F1,Q07021,O00459,P02786,P30154,Q2NKX8,P41440,Q14126,Q96IY1,Q07866,P50402,Q13526,Q6IPU0,P27105,Q7L576,Q6P1K2,P61586,Q13505,Q86Y07,Q9UEY8,Q99570,P30519,Q03001,Q9BXS4,Q9BZD4 34
Signalling to erks 0.3885724882708542 0.3610537847671681 0.7180592405673867 1.0 1.0 7 P62993,Q9ULH0 2
Signaling by wnt in cancer 0.3876907417624012 0.3580972370535502 0.7202705466551551 1.0 1.0 7 P30154,P30153 2
Rnd1 gtpase cycle 0.4145356375845593 0.3536856103201408 0.7235745077540119 1.0 1.0 16 P02786,O75976 2
Incretin synthesis secretion and inactivation 0.373289902280126 0.3504968657714785 0.7259658419164912 1.0 1.0 4 P61009,Q15005,P35222 3
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.373289902280126 0.3504968657714785 0.7259658419164912 1.0 1.0 4 P61009,Q15005,P35222 3
Rhob gtpase cycle 0.4170941805496301 0.3461890678136719 0.7292006299909755 1.0 1.0 18 P02786,P41440 2
Rac3 gtpase cycle 0.4350469058825064 0.3447557114730878 0.7302780311116588 1.0 1.0 31 Q9UQB8,P50402,Q14739,Q86Y07,Q7L576,P02786,Q14126 7
Apc c cdc20 mediated degradation of cyclin b 0.3970701182730882 0.3433916344714584 0.7313038520868678 1.0 1.0 11 P30260,Q16763,Q9H1A4,P14635 4
Insulin receptor recycling 0.3926902439270466 0.3397491368263056 0.734045454597817 1.0 1.0 10 Q9Y487 1
Translocation of slc2a4 glut4 to the plasma membrane 0.4339514589339717 0.3381321486430284 0.7352636047557208 1.0 1.0 33 Q9UIQ6 1
Dna damage recognition in gg ner 0.4071242507295107 0.3378805971891895 0.7354531697697055 1.0 1.0 15 P54727,Q9UNS2,P41208,Q13098,Q9UGN5,Q92905,Q99627,Q7L5N1 8
Phase i functionalization of compounds 0.4052939642022667 0.3319682896963319 0.7399132036246308 1.0 1.0 15 Q9NUB1,Q15185,P07099,O43169,Q5VT66 5
Auf1 hnrnp d0 binds and destabilizes mrna 0.4298259942205542 0.3281301944360736 0.7428132248814288 1.0 1.0 40 P28072,P60900,P49721,P28070,P25788,P20618 6
Regulation of cholesterol biosynthesis by srebp srebf 0.4255533926401689 0.3278272650052528 0.7430422710281159 1.0 1.0 26 Q9UBM7,P37268,O76062 3
Map2k and mapk activation 0.3816483521967196 0.3264690165936398 0.7440695274319411 1.0 1.0 8 P30086 1
Intrinsic pathway for apoptosis 0.4130351697332536 0.3257707286262789 0.7445978268073561 1.0 1.0 19 P31751 1
Gpvi mediated activation cascade 0.3738980342001524 0.3254120699053926 0.7448692217359336 1.0 1.0 6 P61586 1
Resolution of abasic sites ap sites 0.4209594308623657 0.3218073876663478 0.7475986172375753 1.0 1.0 24 P18887,Q9NR33,P56282,P49005,P27694,Q07864,P40938,P78549,Q9UGN5,P41440,P28340,P40937,P27695,Q9Y2S7 14
Srp dependent cotranslational protein targeting to membrane 0.2332193956154175 0.3210872228026558 0.7481442928081774 1.0 1.0 89 P62701,P15880,P62081,P61254,P62829,P62280,P62244,P62273,P83881,P61353,Q9UHB9,P62913,P18621,P62753,P23396,P62263,P61513,P61927,P62841,P18124,P61313,P84098,P62847,P39023,P60468,P60866,P63220,P62241,Q02878,P62750,Q15005,P46783,P18077,P08865,P27635,P46776,P25398,P32969,P62851,P08708,P46779,Q9Y3U8,P83731,Q02543,P62266,P35268,Q15629 47
Mapk family signaling cascades 0.3098396270169402 0.3122642390979918 0.7548397152223241 1.0 1.0 77 P28072,P49720,P30153,P60900,P28074,Q13555,P06493,P41240,Q99460,P49721,P28070,Q9HCE1,P48556,Q99956,P62993,O00459,Q96P70,P30154,O43242,P51665,Q9UL46,Q96S59,P62140,P20618,O14980,O00231,Q99436,Q16512,P25788,P30086 30
Recruitment of mitotic centrosome proteins and complexes 0.4201320234620321 0.3103602882306367 0.7562869895005742 1.0 1.0 26 P30153,Q9H6D7,O75935,Q7Z4H7,P41208,Q96CW5,P06493,P43034,P61163,Q9BSJ2,O94927,Q7Z460,P07437 13
Signaling by pdgf 0.3687960896757175 0.3094167616282493 0.7570045216288548 1.0 1.0 6 P40763,O00459,P62993 3
Downstream signal transduction 0.3687960896757175 0.3094167616282493 0.7570045216288548 1.0 1.0 6 P40763,O00459,P62993 3
Rho gtpases activate cit 0.368316380445633 0.2964747309844432 0.7668675617586072 1.0 1.0 7 P61586 1
Ion transport by p type atpases 0.3869061146962422 0.2924516388485168 0.7699413309027785 1.0 1.0 13 Q13555,P35670,P98194,Q04656,Q9NQ11,Q9HD20 6
Signaling by hedgehog 0.4024558241177473 0.2908782566606703 0.7711444313059321 1.0 1.0 52 P28072,P48729,P49720,P48556,P60900,Q9BUF5,Q9UBV2,P28074,Q99436,P49721,Q96J02,P28070,O43242,O00231,P25788,P20618,Q9BVA1,Q9UL46 18
Phosphorylation of the apc c 0.3831220925024172 0.2901464135775461 0.7717042293270859 1.0 1.0 12 P30260,Q16763,Q9H1A4,P14635 4
Mrna decay by 3 to 5 exoribonuclease 0.3891301348293657 0.2823911839343289 0.7776435742362313 1.0 1.0 15 Q9Y3B2,Q9GZS3,Q9Y450,Q6PGP7 4
Rna polymerase iii transcription 0.3726562705543583 0.2782326592969669 0.7808337657594013 1.0 1.0 10 Q9UKN8,O15160 2
Darpp 32 events 0.3649295292144708 0.2758150088349384 0.7826901553206962 1.0 1.0 8 P30153,P30154,Q14738,P62136,Q00535 5
Cilium assembly 0.3963860071980687 0.2695082848568215 0.7875385676123408 1.0 1.0 52 P30153,O75935,Q15019,P06493,P43034,P61163,Q8TAG9,Q7Z460,Q9BVA1,P07437,Q96KP1,Q9H6D7,Q10713,A6NIH7,A0AVF1,Q7Z4H7,P41208,P36405,P78371,Q92538,Q9BUF5,P18085,O00471,O94927,Q92973 25
Signaling by tgf beta receptor complex 0.3919541740302949 0.268889134694488 0.7880149984146141 1.0 1.0 18 O14980,P50750,Q93008,Q9Y3F4,P62140,P62136,P61586,Q96PU5,Q9Y624 9
Signaling by tgfb family members 0.3919541740302949 0.268889134694488 0.7880149984146141 1.0 1.0 18 O14980,P50750,Q93008,Q9Y3F4,P62140,P62136,P61586,Q96PU5,Q9Y624 9
Slc mediated transmembrane transport 0.4040005439783762 0.2657865407613861 0.7904036094240872 1.0 1.0 25 Q70HW3,Q9Y2D2,O00400,P30825,P11166 5
Ub specific processing proteases 0.3518910966533197 0.2620277720680879 0.7933000309969074 1.0 1.0 66 P28072,P49720,P60900,P28074,O94966,Q99460,P49721,P28070,Q13309,P48556,P45974,Q96K76,O43242,P51665,Q9UL46,Q9NZL9,P20618,Q9HBM6,Q93008,Q99436,O00231,P25788 22
Mapk6 mapk4 signaling 0.4013588442458285 0.2527167757990108 0.8004870833787301 1.0 1.0 46 P28072,P48556,P49720,O14980,P60900,P28074,P06493,Q99436,P49721,O00231,P28070,O43242,P25788,Q16512,P20618,Q9HCE1,Q9UL46 17
Toll like receptor 9 tlr9 cascade 0.3728972884250378 0.2448604270363823 0.8065645036908828 1.0 1.0 14 P30153,P09429,P51812,Q99570,P61088,Q13616,P30154,Q15750 8
Erk mapk targets 0.349826593088293 0.2440266096634359 0.8072102112486845 1.0 1.0 7 P30154,P30153 2
Mapk targets nuclear events mediated by map kinases 0.349826593088293 0.2440266096634359 0.8072102112486845 1.0 1.0 7 P30154,P30153 2
Cellular response to chemical stress 0.3057029137993519 0.2388358498268183 0.8112328703872844 1.0 1.0 75 P28072,P67870,P60900,Q9BZK7,P49721,P28070,P25788,P30519,O43819,P20618,P09601 11
Signaling by fgfr1 in disease 0.354344988221984 0.2372287174360386 0.8124793588011163 1.0 1.0 9 Q9UBW7,Q16630,O95429,Q92614 4
Fgfr1 mutant receptor activation 0.354344988221984 0.2372287174360386 0.8124793588011163 1.0 1.0 9 Q9UBW7,Q16630,O95429,Q92614 4
Cargo trafficking to the periciliary membrane 0.3815271413672552 0.2289598733868055 0.8189001040981001 1.0 1.0 20 P50990,Q10713,P36405,P78371,P18085,P17987,A6NIH7,O00471,Q8TAG9,Q92538,Q9UPT5,Q96KP1 12
Sphingolipid metabolism 0.3918090980325981 0.2288528143495926 0.8189833159694155 1.0 1.0 26 P06280,Q96G23,P16278,P06865 4
Toll like receptor cascades 0.3785996078763411 0.2270015312147472 0.8204225515113945 1.0 1.0 19 P30153,P50570,P09429,P51812,P04114,Q99570,P61088,P30154,Q13616,Q15750,Q99538 11
Reduction of cytosolic ca levels 0.3302931596091237 0.2241841611085594 0.82261400744038 1.0 1.0 4 P23634,P20020,P16615 3
Nephrin family interactions 0.3451898876792126 0.2227892573394586 0.8236995292977567 1.0 1.0 8 O14936 1
Prolonged erk activation events 0.3300749429781732 0.2134328001406004 0.8309893990356851 1.0 1.0 5 P28482,Q9ULH0,P46108,P46109 4
Defective cftr causes cystic fibrosis 0.3876159016502958 0.203406320728976 0.8388174598514271 1.0 1.0 42 P28072,P60900,P49721,P28070,P25788,P20618 6
Regulation of signaling by cbl 0.32865004260717 0.2005714803924205 0.8410336602228483 1.0 1.0 6 O00459 1
Amino acids regulate mtorc1 0.3459668170053291 0.2005244885872385 0.8410704077938729 1.0 1.0 11 P42345 1
Response to elevated platelet cytosolic ca2 0.386649910200811 0.1999062375898597 0.8415539120201623 1.0 1.0 33 P07737,O43852,Q06481,Q08380,Q9NTK5,P07602 6
Cohesin loading onto chromatin 0.3412564002414918 0.1971580936341887 0.843703823336968 1.0 1.0 10 Q7Z5K2 1
Retrograde transport at the trans golgi network 0.3606652797246682 0.19540895369134 0.8450728076942478 1.0 1.0 17 O60499,P11717 2
Rac2 gtpase cycle 0.383867853827953 0.1933679422676122 0.846670819966262 1.0 1.0 33 P50402,Q14739,Q86Y07,Q7L576,P02786,Q14126,Q13505 7
Recruitment of numa to mitotic centrosomes 0.3781341461159291 0.1874430609642802 0.8513132630939826 1.0 1.0 29 Q9BUF5,P30153,Q9H6D7,O75935,Q7Z4H7,P41208,Q96CW5,P06493,P43034,P61163,Q9BSJ2,O94927,Q7Z460,Q9BVA1,P07437 15
Signaling by notch 0.3552647459384689 0.1863167009508121 0.8521964113057394 1.0 1.0 58 P28072,P49720,P67809,P60900,P28074,Q9BZK7,P49721,P28070,P25788,P20618 10
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.3322361967072124 0.1846032123544676 0.8535402661568656 1.0 1.0 9 Q16763,Q9H1A4 2
Regulation of lipid metabolism by pparalpha 0.3693375999029499 0.1794628269203851 0.8575743032578802 1.0 1.0 25 P37268 1
Cytokine signaling in immune system 0.2037305273774673 0.1761741769145446 0.8601571073061236 1.0 1.0 158 P28072,Q96EE3,P30153,P60900,P49720,P19525,P28074,Q13555,O00170,P41240,Q99460,P49721,P28070,P31751,Q12769,P10321,P48556,P57740,P62993,P06730,P51812,Q13277,P04439,Q14240,Q15370,O00459,P61221,Q9H3K6,P30154,O43242,Q99439,Q13126,P51665,Q9UL46,P11233,Q13526,P20618,Q15369,P09429,O00231,Q99436,Q53EL6,P25788,P09601 44
Telomere c strand lagging strand synthesis 0.358378987279519 0.1756419277733807 0.8605752607704382 1.0 1.0 20 Q9NYB0,P49642,P49005,Q14181,P27694,P40938,P49643,P41440,P28340,Q9Y2S7 10
Hiv infection 0.2075046967942887 0.1741240888944109 0.8617679421756717 1.0 1.0 132 P28072,Q96EE3,P49720,P60900,P28074,P49721,P28070,P18615,Q8WUM4,P04439,P62826,O43242,Q96PU5,Q92804,Q8IXH7,Q9BXS5,P20618,Q9HBM6,Q15369,P50750,P35269,O00231,P25788 23
Cell surface interactions at the vascular wall 0.3507297580594514 0.1741027996786325 0.8617846729792265 1.0 1.0 17 P78310,P04114,O00459,P06756,Q92896,Q9Y624 6
Diseases of metabolism 0.3738768912765139 0.1738820342112514 0.8619581721585496 1.0 1.0 44 O43505,P06865,P15586,P13807,Q99707,O75874,P16278,Q8NCH0,P54802,P48506,O94766 11
Rho gtpases activate iqgaps 0.3233004616641826 0.1730678731431138 0.8625980773708626 1.0 1.0 8 Q9BUF5,P63000,Q9BVA1 3
Extra nuclear estrogen signaling 0.3335217106003143 0.1672855282700985 0.8671453904551818 1.0 1.0 12 P04899,Q99873,P31751 3
Myd88 independent tlr4 cascade 0.333223989292609 0.1609025377608852 0.8721701635065218 1.0 1.0 13 P30153,P09429,P51812,P61088,Q13616,P30154,Q15750 7
Toll like receptor tlr1 tlr2 cascade 0.333223989292609 0.1609025377608852 0.8721701635065218 1.0 1.0 13 P30153,P09429,P51812,P61088,Q13616,P30154,Q15750 7
Interleukin 17 signaling 0.32710639518375 0.1608405103766096 0.8722190179234688 1.0 1.0 11 P30153,P51812,P61088,Q13616,P30154,Q15750 6
Regulation of mrna stability by proteins that bind au rich elements 0.3442715154008493 0.1585579334251632 0.8740171736830458 1.0 1.0 58 P28072,P60900,P49721,Q9Y3B2,P28070,P25788,P20618,Q92973 8
Rhoa gtpase cycle 0.3675366831946255 0.157636736034882 0.8747430543017398 1.0 1.0 42 Q9Y4F1,Q14739,Q07021,P27105,P02786,P41440 6
Neurexins and neuroligins 0.3082059659498753 0.1574906824895445 0.8748581505579294 1.0 1.0 6 Q9HCM4,O14936,Q96HC4 3
Abc transporter disorders 0.3667887371873742 0.1572404138214578 0.875055378810417 1.0 1.0 43 P28072,P60900,P49721,P28070,P25788,P20618 6
Transcriptional regulation by ventx 0.336826899905454 0.1570732436709266 0.8751871242629556 1.0 1.0 15 P30260,Q9HCE1,Q9H1A4,Q16763 4
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.3192272223594727 0.1521175680897102 0.8790942081257374 1.0 1.0 10 P14635 1
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3218363815318854 0.1510441306164326 0.8799409040216317 1.0 1.0 11 P30260,Q16763,Q9H1A4 3
Apc cdc20 mediated degradation of nek2a 0.3218363815318854 0.1510441306164326 0.8799409040216317 1.0 1.0 11 P30260,Q16763,Q9H1A4 3
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.3149357047946953 0.1503382173332708 0.880497782538558 1.0 1.0 9 P06493,Q99873,P14635 3
Sensory perception 0.3509483454857984 0.1500315389388608 0.8807397323993789 1.0 1.0 23 P04114,P01130,P47755,Q00013,Q6NUM9,O14936 6
Ephb mediated forward signaling 0.3216189455080058 0.140119302709054 0.8885657296898057 1.0 1.0 13 O15145,P63000,Q16512,P61586,Q92747,P23528 6
Signal transduction by l1 0.3058945266229362 0.1348351396600539 0.892742222092032 1.0 1.0 9 P67870,P63000,Q16512,P06756,P13591 5
Base excision repair 0.349398466677513 0.1345439372441761 0.8929724700072286 1.0 1.0 28 Q9NYB0,P18887,P16104,Q9NR33,P56282,P49005,P27694,P40938,P78549,Q9UGN5,P41440,P28340,Q9Y2S7 13
Response of mtb to phagocytosis 0.3121123081945868 0.1344302320893814 0.8930623768447352 1.0 1.0 11 P51149,Q9H267,P28482,P52294,P20339,P14373,Q14974,P23246,P00558,Q9UI12 10
Infection with mycobacterium tuberculosis 0.3121123081945868 0.1344302320893814 0.8930623768447352 1.0 1.0 11 P51149,Q9H267,P28482,P52294,P20339,P14373,Q14974,P23246,P00558,Q9UI12 10
Cytosolic sensors of pathogen associated dna 0.318758781963624 0.1308731709855317 0.8958756385623015 1.0 1.0 14 P62875,P78527,P19388,Q13546,Q9UJV9,O14802,P13010,O15160,Q9NZI8,Q9H2U1 10
Death receptor signalling 0.3232297013839559 0.1294645418047642 0.8969900803266417 1.0 1.0 16 P49327,Q92974,O95429,P63244,P63000,Q15750,P61586,P52565,Q92769 9
Fceri mediated mapk activation 0.2871785573889077 0.1278508658424565 0.8982669952098559 1.0 1.0 5 Q16512,P62993 2
Rho gtpases activate ktn1 0.2932542641915175 0.12576549853691 0.8999175530521297 1.0 1.0 7 P61586 1
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.2990921980709658 0.1194747894625038 0.9048992120526969 1.0 1.0 10 Q16763,Q9H1A4 2
Pentose phosphate pathway 0.2848761408083454 0.1186650645255832 0.9055407154004098 1.0 1.0 6 P37837,P52209,O95336,Q96G03,P11413 5
Hdr through homologous recombination hrr 0.3343702209363829 0.1142851695607886 0.909011738444536 1.0 1.0 27 P49005,Q9UQ84,P41440 3
Mitotic spindle checkpoint 0.3255857228190664 0.1139349383613734 0.9092893690842814 1.0 1.0 56 Q96EE3,P30153,Q53HL2,P50748,Q9H1A4,Q9BZD4,Q6IPU0,Q6P1K2,P30260,P30154,Q16763,Q2NKX8,O60566,Q96IY1 14
Resolution of sister chromatid cohesion 0.3165740843005847 0.113801527468659 0.909395127716598 1.0 1.0 60 Q96EE3,P30153,Q7Z5K2,Q53HL2,P50748,P14635,P06493,Q6IPU0,Q9BZD4,Q6P1K2,P30154,Q2NKX8,O60566,Q96IY1 14
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.3169884177945311 0.1134860376139918 0.9096452319372772 1.0 1.0 18 P16278 1
Anchoring of the basal body to the plasma membrane 0.3308468170385086 0.11152233963055 0.9112021516316128 1.0 1.0 26 P30153,Q9H6D7,O75935,Q15019,Q7Z4H7,P41208,P06493,P43034,P61163,O94927,Q7Z460,P07437 12
Copi independent golgi to er retrograde traffic 0.3236981113090547 0.111083055234279 0.911550485539445 1.0 1.0 22 Q9UJW0,Q9BUF5,Q9H2M9,Q15102,O75935,P47756,Q10471,P43034,P47755,Q9BVA1 10
Rhou gtpase cycle 0.3069936838744174 0.1102872470292028 0.9121815709610612 1.0 1.0 15 O43396,P60953,P62993,Q93008,O00459,Q03001,Q16512,Q9NNW5 8
Signaling by ptk6 0.2984947256349037 0.1102616908591132 0.9122018382295768 1.0 1.0 12 Q96JJ3,P63000,P24941,P61586,P11802 5
Processive synthesis on the c strand of the telomere 0.2921555621602731 0.110041773842701 0.9123762453293516 1.0 1.0 10 P49005,Q9Y2S7,P28340,P27694 4
Circadian clock 0.2959143508230225 0.1069917659904007 0.914795512046424 1.0 1.0 12 Q9BZK7,Q86X55,Q9BWF3,P62140,P43490 5
Intra golgi and retrograde golgi to er traffic 0.2134273179862803 0.1054724052506029 0.916000965257153 1.0 1.0 85 O43731,P11717,P24390,O60476,O60499,O00461 6
Aurka activation by tpx2 0.3254727487864564 0.1048307594512332 0.9165101020047616 1.0 1.0 26 P30153,Q9H6D7,O75935,Q7Z4H7,P41208,P06493,P43034,P61163,O94927,Q7Z460,P07437 11
Disorders of transmembrane transporters 0.2471094802048877 0.1031303512569591 0.9178595166290237 1.0 1.0 78 P28072,P60900,P28074,Q9Y2D2,P49721,O00400,P28070,P25788,P20618 9
Interconversion of nucleotide di and triphosphates 0.3032001961369855 0.1024511159243271 0.9183986124418606 1.0 1.0 16 P17812,Q9NRF8,P31350,Q9H773,P23919,P04818 6
Triglyceride catabolism 0.2708465212830127 0.1003920888266333 0.9200330502391952 1.0 1.0 6 P62140,P41247 2
Metabolism of nitric oxide nos3 activation and regulation 0.2670961058180356 0.1003864956733055 0.9200374904989236 1.0 1.0 5 P50570,P07900 2
Regulation of plk1 activity at g2 m transition 0.3266873977061955 0.1003392831915947 0.920074971366062 1.0 1.0 30 P30153,Q9H6D7,O75935,Q7Z4H7,P41208,P14635,P06493,P43034,Q15691,P07900,P61163,Q13616,O94927,Q7Z460,P62140,P07437 16
Vxpx cargo targeting to cilium 0.2801006227858793 0.095734921411907 0.923731104993114 1.0 1.0 10 O00471,Q96KP1,Q92538 3
Protein folding 0.3227096381279024 0.0940063635460388 0.9251041017461324 1.0 1.0 32 Q9BUF5,P67870,P78371,Q99471,Q15477,Q15813,Q9BTW9,Q9BVA1,Q99426,O95302 10
Signaling by csf3 g csf 0.2680954287467433 0.0934320476674502 0.9255603315074088 1.0 1.0 7 Q15369,P62993 2
Rho gtpases activate formins 0.3064579068264225 0.0892187003784094 0.9289081038898686 1.0 1.0 56 P60953,P30153,Q96EE3,Q53HL2,P50748,P07737,O43264,P43034,Q9BW27,Q9Y266,Q12769,Q7Z460,Q9BVA1,P57740,P63000,P30154,Q14738,Q2NKX8,Q96IY1,Q6IPU0,Q15691,Q15005,Q6P1K2,P61586,P46060,O14980,Q9BUF5,O43684,Q92674,Q9BZD4,O60566,P35080 32
Transcriptional regulation by runx1 0.2692820361935742 0.0887604524292342 0.9292722879784624 1.0 1.0 70 P28072,P67870,P49720,Q16625,P60900,P28074,P49721,P28070,P25788,Q99873,P20618 11
Global genome nucleotide excision repair gg ner 0.32050774009652 0.0887559674843619 0.9292758523788353 1.0 1.0 38 P54727,Q9UNS2,Q13098,P49005,P40938,P61088,P12004,Q9NR33,Q92905,P41440,Q99627,Q7L5N1,P41208,P28340,P18887,P56282,Q86WJ1,Q07864,Q9UGN5,P40937,P27694,Q9Y2S7 22
Influenza infection 0.1817386072385158 0.0879181155572136 0.9299417582252764 1.0 1.0 125 Q96EE3,P49790,P19525,P62701,P62081,P61254,P62829,P62280,Q9BW27,P15880,Q99567,P62244,P62273,P83881,Q00610,Q12769,P62249,P61353,P62913,P18621,P57740,P62753,P23396,P62263,P62826,P61513,O95639,P07900,P62841,P61927,P18124,P61313,P84098,P62847,P39023,Q02878,P60866,P63220,P62241,P62750,P46783,P18077,P08865,P27635,P46776,P25398,P32969,P62851,O14980,P19387,P35269,P08708,O00410,P46779,Q9Y3U8,P83731,Q02543,P62266,P35268,P26373 60
Rhoh gtpase cycle 0.2955223656280787 0.0870961527772998 0.9305950834055304 1.0 1.0 19 P02786,Q9BXS4 2
Abc family proteins mediated transport 0.3089127279465156 0.086716302912889 0.9308970173831028 1.0 1.0 53 P28072,P49720,P60900,P28074,P49721,P28070,P25788,P20618,P08183 9
Constitutive signaling by aberrant pi3k in cancer 0.2523708415221829 0.0816407533214992 0.9349323929803712 1.0 1.0 6 O00459,P62993,O43815 3
Signaling by gpcr 0.3092766544657412 0.0797119584221959 0.9364663482750462 1.0 1.0 36 P30153,Q9BYT8,P04899,P42892,O00459,P31751,P61586,Q9NRV9,P07602 9
Antigen presentation folding assembly and peptide loading of class i mhc 0.2749367474851616 0.0779604452800293 0.9378595172829034 1.0 1.0 15 P04439,P10321,Q9NZ08 3
Deadenylation dependent mrna decay 0.3063346532103771 0.0778806128179277 0.9379230212931668 1.0 1.0 35 Q96C86,A5YKK6,P06730,Q14240,Q92600,Q9GZS3,P26196,Q15477,P23588,Q9Y3B2,Q9HBH5,Q9Y450,Q9Y4Y9,Q6PGP7 14
Metabolism of vitamins and cofactors 0.3039554705654389 0.076494270318172 0.9390258722448914 1.0 1.0 46 Q9NRN7,P00374,P04114,Q99707,O75874,Q8NFF5,P01130,P41440,P43490,P11166 10
Mrna decay by 5 to 3 exoribonuclease 0.2556484292011524 0.0763386777799583 0.9391496551868004 1.0 1.0 9 Q9Y4Y9 1
Signaling by kit in disease 0.2457627118644089 0.076268674504903 0.9392053473560524 1.0 1.0 6 P62993,P07947,O00459,P40763,P42224 5
Inactivation of csf3 g csf signaling 0.2457627118644043 0.0762686745048997 0.9392053473560552 1.0 1.0 6 Q15369,Q15370,Q93034,P40763,P42224 5
Signaling by pdgfr in disease 0.2437486947234512 0.07476031903535 0.940405414247136 1.0 1.0 6 O00459,P62993 2
Triglyceride metabolism 0.2401200342464414 0.070017359313884 0.9441798428115684 1.0 1.0 7 P62140,P41247 2
Transport of vitamins nucleosides and related molecules 0.2487768449363632 0.0696063307916749 0.9445069979221395 1.0 1.0 10 O00400 1
Regulation of tp53 activity 0.2830632436033363 0.0686765576259357 0.9452470784416616 1.0 1.0 54 P67870,P30153,Q13472,P06493,P42771,Q13526,Q9HBM6,Q8WXE1,Q9UQ84,Q00535,P30154,Q8TBX8,P31751,P42345,Q92804 15
Dual incision in tc ner 0.2830687008054254 0.0651465464575595 0.9480573204043596 1.0 1.0 33 P41440,P49005,Q9NR33 3
G alpha i signalling events 0.2602697619880373 0.0628551951361558 0.9498818133564646 1.0 1.0 20 P04899,Q9NRV9,P30153,P07602 4
Rhoq gtpase cycle 0.2560758387138697 0.0628131421476634 0.9499153006153522 1.0 1.0 18 P02786 1
Transport to the golgi and subsequent modification 0.2250501705772804 0.060249278098581 0.9519570987216084 1.0 1.0 70 Q9UJW0,P04066,O43731,O00743,P24390,O60476,Q92734,Q92538,Q9UP83,O15027 10
Complex i biogenesis 0.2693839410027727 0.0599786135678443 0.9521726679193409 1.0 1.0 33 O95182,P03886 2
Extension of telomeres 0.2608095201473792 0.0583955698746529 0.9534335434804628 1.0 1.0 29 Q9NYB0,P49642,O00743,P49005,Q14181,P27694,P40938,P41440,P49643,P28340,Q5H9R7,Q9Y2S7,P24941 13
Signaling by ntrks 0.2589668612923554 0.0581666832617603 0.953615858677508 1.0 1.0 28 P30153,P50570,P62993,Q9ULH0,P51812,O00459,P30154,P61586,Q00535,P11233 10
Opioid signalling 0.234544495794175 0.0567351150981116 0.954756201251424 1.0 1.0 16 P30153,Q13555,P04899,P30154,Q00535 5
Transcription coupled nucleotide excision repair tc ner 0.2551081596076384 0.0564635753579671 0.9549725118654382 1.0 1.0 44 P18887,Q9NR33,P49005,Q92905,P41440,Q9ULR0 6
Phospholipid metabolism 0.246932516313713 0.0561167014522206 0.9552488390686444 1.0 1.0 50 P67870,Q8IY17,Q9NPH0,Q8NCC3,Q8TBX8,Q8IV08 6
Biological oxidations 0.2506616808678081 0.0554561747930697 0.9557750436374016 1.0 1.0 41 Q9NUB1,P28161,O00170,Q15185,Q99707,O43252,Q9NZL9,P07099,O43169,Q5VT66 10
Homology directed repair 0.2388352873025182 0.0542712961865607 0.9567190181636313 1.0 1.0 44 Q9NXR7,P18887,Q9NR33,Q9NY27,P56282,P49005,Q13472,Q8WXE1,Q9UQ84,P41440,P28340,Q9UNS1 12
Trna processing 0.1803631963957462 0.0537856228837309 0.9571059642152452 1.0 1.0 56 Q9NXH9,Q9H974,Q5VV42,Q99575,Q5KU26 5
Rho gtpases activate paks 0.2052202283849955 0.053473048383386 0.9573550041918876 1.0 1.0 9 P60953,P21333,P63000,P35579,Q16512,P62140,Q14247,P35580 8
Copi mediated anterograde transport 0.1791341573632484 0.052716020876303 0.9579581739613404 1.0 1.0 48 P35606,O75935,P24390,P61163,Q9UP83,Q9BVA1,Q9Y2V7,Q9Y678,Q8N6T3,P47756,P53618,O95249,Q9UJW0,Q9UBF2,O43731,Q92538,Q9BUF5,O15498,P18085,P47755,Q9Y3B3 21
Sensory processing of sound 0.2169287849357706 0.0525283503099851 0.9581077062306268 1.0 1.0 17 Q00013,O14936,P47756,P47755 4
Transcription of the hiv genome 0.2282084488027696 0.0525100047526964 0.9581223236942268 1.0 1.0 29 P18615,Q15369,Q92804,P35269,Q9HBM6,Q8IXH7 6
Insulin processing 0.204197527234154 0.0523238160635932 0.9582706768318584 1.0 1.0 11 O00471,Q96KP1 2
Trna processing in the nucleus 0.196271310281447 0.052217001475718 0.958355786195184 1.0 1.0 43 Q5KU26 1
Protein ubiquitination 0.2186720869723979 0.0517513479101574 0.9587268223080914 1.0 1.0 24 P04439,P78527,P45974,Q9GZS3,Q16763 5
The role of nef in hiv 1 replication and disease pathogenesis 0.199687749246083 0.0512864051708904 0.9590973009504784 1.0 1.0 12 P04439,Q9BXS5,P63000,Q96CW1,Q10567 5
Semaphorin interactions 0.2045605434068839 0.0512503462924398 0.9591260339864264 1.0 1.0 15 Q9BPU6,P07900,Q16512,P61586,Q00535,P23528 6
Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.1968467663718383 0.0511584833241288 0.9591992340063212 1.0 1.0 11 P04439 1
Potential therapeutics for sars 0.182903043733595 0.0509586137074168 0.9593584991518872 1.0 1.0 34 Q99720 1
Signaling by alk in cancer 0.1579140876549927 0.050313404478986 0.9598726420695344 1.0 1.0 30 O94979,P49589,Q07866,Q14203,P62993,P62753,P10644,Q13616,Q92734,O43815,P26641,P40763,Q9NR09 13
Eph ephrin signaling 0.1893774199891966 0.0502017380650683 0.9599616265266058 1.0 1.0 26 P60953,O15145,P63000,Q96CW1,Q16512,Q15375,P61586,Q92747,P23528 9
Rhov gtpase cycle 0.1918927754168068 0.0499908866634308 0.9601296506318956 1.0 1.0 15 Q13813,O43396,P60953,Q8TAA9,P46940,Q93008,P67936,O96013,Q01082,Q03001,Q16512,Q9NNW5,Q00610,Q96KM6 14
Retrograde neurotrophin signalling 0.1788995306728706 0.0498800125072522 0.9602180051823516 1.0 1.0 7 Q96CW1,P50570,Q00610 3
Eph ephrin mediated repulsion of cells 0.1753755715218836 0.0490225396088821 0.9609013335219848 1.0 1.0 12 Q92542,P09497,P07948,P63000,O94973,Q96CW1,Q00610,Q15375,P63010,O95782,P07947 11
Recycling pathway of l1 0.1652059412774429 0.0488835947738025 0.9610120627052297 1.0 1.0 17 Q9BUF5,Q9BVA1,P50570 3
Peptide hormone metabolism 0.1625245258338717 0.0487449054625253 0.9611225890041356 1.0 1.0 16 P61009,Q86YB8,O60645,Q8TAD4,P35222,P67812,Q9NV70,Q15005,O00471,Q8TAG9,Q8IYI6,P33176,Q9UPT5,O75787,Q96KP1 15